PREFIX obo:
PREFIX rdf:
PREFIX rdfs:
PREFIX xsd:
obo:REO_0000552 a rdfs:Class ;
rdfs:label "obsolete_analog reagent role" ;
rdfs:comment "a reagent role inhering in a synthetic material entity that is designed to exhibit structural similarity to a naturally occurring material. This similarity is such that the bearer can mimic some attributes or activity activity of this material entity, while also exhibiting specified structural differences that allow it to probe or alter the environment of the bearer in some way." ;
rdfs:subClassOf .
obo:CL_0002131 a rdfs:Class ;
rdfs:label "regular ventricular cardiac myocyte" ;
rdfs:comment "Regular cardiac myocyte of a cardiac ventricle." ;
rdfs:subClassOf obo:CL_0002098 .
obo:REO_0000729 a rdf:Property ;
rdfs:label "aggregate part of" ;
rdfs:comment "relationship between an object and a collection of which it is a separable part" ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf .
a rdf:Property ;
rdfs:label "transformation_of"@en ;
rdfs:comment "When an embryonic oenocyte (a type of insect cell) is transformed into a larval oenocyte, one and the same continuant entity preserves its identity while instantiating distinct classes at distinct times. The class-level relation transformation_of obtains between continuant classes C and C1 wherever each instance of the class C is such as to have existed at some earlier time as an instance of the distinct class C1 (see Figure 2 in paper). This relation is illustrated first of all at the molecular level of granularity by the relation between mature RNA and the pre-RNA from which it is processed, or between (UV-induced) thymine-dimer and thymine dinucleotide. At coarser levels of granularity it is illustrated by the transformations involved in the creation of red blood cells, for example, from reticulocyte to erythrocyte, and by processes of development, for example, from larva to pupa, or from (post-gastrular) embryo to fetus or from child to adult. It is also manifest in pathological transformations, for example, of normal colon into carcinomatous colon. In each such case, one and the same continuant entity instantiates distinct classes at different times in virtue of phenotypic changes." ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000697 .
obo:REO_0000679 a rdf:Property ;
rdfs:label "bears_concretization_of" ;
rdfs:comment "a relation between a material information bearer or material genetic sequence bearer and generically dependent continuant that carries information or sequence content that the bearer encodes" ;
rdfs:domain ;
rdfs:range , obo:REO_0000953 .
a rdf:Property ;
rdfs:label "has_proper_part"@en ;
rdfs:comment "a has_part relation that is transitive but not reflexive (such that no entity can be a proper_part_of itself)" ;
rdfs:range , obo:SO_0000110 , obo:REO_0000988 , obo:REO_0000952 ;
rdfs:subPropertyOf .
obo:REO_0000963 a rdf:Property ;
rdfs:label "has cardinal part" ;
rdfs:comment "a has_part property that is reflexive but not transitive, and relates an entity to its core components at the level of granularity at which the whole entity itself exists (similar to has direct part in this way). Thus, a cell can be said to 'have cardinal part' itself (because the property is reflexive), or a nucleus or other organelle (because these exist at same level of granularity as the cell), but not a DNA molecule or potassium ion (because these are not components at the same level of granularity as the cell)" ;
rdfs:range obo:CL_0000000 , ;
rdfs:subPropertyOf .
obo:RO_0002205 a rdf:Property ;
rdfs:label "has gene product"@en ;
rdfs:comment "x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y" ;
rdfs:domain ;
rdfs:range .
a rdf:Property ;
rdfs:label "proper_part_of"@en ;
rdfs:range ;
rdfs:subPropertyOf .
a rdf:Property ;
rdfs:label "located_in"@en ;
rdfs:comment "Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus" ;
rdfs:domain ;
rdfs:range .
obo:RO_0002204 a rdf:Property ;
rdfs:label "gene product of"@en ;
rdfs:comment "definition \"x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x\"" ;
rdfs:domain ;
rdfs:range .
a rdf:Property ;
rdfs:label "transformed_into"@en ;
rdfs:comment "Obsoleted" ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf .
a rdf:Property ;
rdfs:label "part_of"@en ;
rdfs:comment "Parthood as a relation between instances: The primitive instance-level relation p part_of p1 is illustrated in assertions such as: this instance of rhodopsin mediated phototransduction part_of this instance of visual perception. This relation satisfies at least the following standard axioms of mereology: reflexivity (for all p, p part_of p); anti-symmetry (for all p, p1, if p part_of p1 and p1 part_of p then p and p1 are identical); and transitivity (for all p, p1, p2, if p part_of p1 and p1 part_of p2, then p part_of p2). Analogous axioms hold also for parthood as a relation between spatial regions. For parthood as a relation between continuants, these axioms need to be modified to take account of the incorporation of a temporal argument. Thus for example the axiom of transitivity for continuants will assert that if c part_of c1 at t and c1 part_of c2 at t, then also c part_of c2 at t. Parthood as a relation between classes: To define part_of as a relation between classes we again need to distinguish the two cases of continuants and processes, even though the explicit reference to instants of time now falls away. For continuants, we have C part_of C1 if and only if any instance of C at any time is an instance-level part of some instance of C1 at that time, as for example in: cell nucleus part_ of cell." ;
rdfs:range .
a rdf:Property ;
rdfs:label "output_of" ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf .
obo:BFO_0000053 a rdf:Property ;
rdfs:label "is bearer of"@en ;
rdfs:domain ;
rdfs:range .
a rdf:Property ;
rdfs:label "contained_in"@en ;
rdfs:comment "Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):" ;
rdfs:domain ;
rdfs:range .
a rdf:Property ;
rdfs:label "participates_in"@en ;
rdfs:domain ;
rdfs:range .
a rdf:Property ;
rdfs:label "location_of"@en ;
rdfs:domain ;
rdfs:range .
obo:REO_0000109 a rdf:Property ;
rdfs:label "contains_process"@en ;
rdfs:comment "A relation between a continuant and a process that occurs within the continuant, but in which the continuant is not a participant. The continuant stands in a 'contains' relation to each of the participants in the process." ;
rdfs:domain ;
rdfs:range .
obo:REO_0000325 a rdf:Property ;
rdfs:label "is_subject_of" ;
rdfs:comment """a relation holding between an entity and an information artifact that is about that entity (ie specifies, describes, denotes, mentions that entity).
Used as inverse property of 'is about'.""" ;
rdfs:domain ;
rdfs:range obo:IAO_0000030 .
a rdf:Property ;
rdfs:label "derived_into"@en ;
rdfs:domain ;
rdfs:range .
obo:REO_0000591 a rdf:Property ;
rdfs:label "participation_specified_by" ;
rdfs:comment "a relation holding between an independent continuant and a directive information entity that specifies the participation of this independent continuant in some process" ;
rdfs:domain ;
rdfs:range obo:IAO_0000033 ;
rdfs:subPropertyOf obo:REO_0000326 .
a rdf:Property ;
rdfs:label "derives_from"@en ;
rdfs:comment "Derivation as a relation between instances. The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Derivation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant." ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000697 .
obo:REO_0000090 a rdf:Property ;
rdfs:label "capable_of"@en ;
rdfs:comment "A relation between a material entity (such as a cell) and a process in which some realizable entity inhereing in the material entity is realized." ;
rdfs:domain ;
rdfs:range .
obo:REO_0000326 a rdf:Property ;
rdfs:label "is_specified_by" ;
rdfs:comment "a relation holding between an entity and a directive information entity that prescribes a use, application, or occurrence of the entity)" ;
rdfs:domain ;
rdfs:range obo:IAO_0000033 ;
rdfs:subPropertyOf obo:REO_0000325 .
obo:REO_0000327 a rdf:Property ;
rdfs:label "is_denoted_by" ;
rdfs:comment "a relation holding between an entity and an information artifact that references this entity (but does not prescribe a use, application, or occurrence of the entity)" ;
rdfs:domain ;
rdfs:range obo:IAO_0000030 ;
rdfs:subPropertyOf obo:REO_0000325 .
a rdf:Property ;
rdfs:label "agent_in"@en ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf .
obo:CL_0002054 a rdfs:Class ;
rdfs:label "Fraction E immature B cell" ;
rdfs:comment "An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive." ;
rdfs:subClassOf obo:CL_0000816 .
obo:OBI_0000681 a rdfs:Class ;
rdfs:label "separation into different composition objective" ;
rdfs:comment "is the objective to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities)" ;
rdfs:subClassOf obo:OBI_0000639 .
obo:REO_0000716 a rdf:Property ;
rdfs:label "encoded_in_material_bearer" ;
rdfs:comment """a shorcut relation linking an information content entity or genetic sequence region to a material information bearer or informatioon macromolecule, respectively.
is shortcut for: 'is concretized as' some ('inheres in' some (material information bearer' or 'information macromolecule')""" ;
rdfs:domain ;
rdfs:range .
obo:REO_0000315 a rdf:Property ;
rdfs:label "specifies_execution_of" ;
rdfs:comment "is this property (and its children) a shortcut relation, expanding to specifies_occurrence_of some (has_participant some . . .)" ;
rdfs:domain obo:IAO_0000033 ;
rdfs:range obo:OBI_0000011 ;
rdfs:subPropertyOf obo:REO_0000593 .
obo:REO_0000588 a rdf:Property ;
rdfs:label "specifies_occurrence_of" ;
rdfs:comment "relation between some action specification an a processual entitiy whose occurrence it specifies." ;
rdfs:domain obo:IAO_0000033 ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000313 .
obo:IAO_0000136 a rdf:Property ;
rdfs:label "is about"@en ;
rdfs:comment "is_about is a (currently) primitive relation that relates an information artifact to an entity."@en ;
rdfs:domain obo:IAO_0000030 ;
rdfs:range .
obo:OBI_0000833 a rdf:Property ;
rdfs:label "objective_achieved_by" ;
rdfs:comment "This relation obtains between a a objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process." ;
rdfs:domain obo:IAO_0000033 ;
rdfs:range obo:OBI_0000011 ;
rdfs:subPropertyOf obo:REO_0000411 .
obo:REO_0000411 a rdf:Property ;
rdfs:label "specification_achieved_by" ;
rdfs:domain obo:IAO_0000033 ;
rdfs:range obo:OBI_0000011 .
obo:REO_0000314 a rdf:Property ;
rdfs:label "specifies_use_of" ;
rdfs:comment """relation between some action specification and some processed material bearing some function or role that is realized in the execution of the specified action
Ex: the action specifications outlined in an immunization protocol would specify the participation of some T cell or B cell, but specifies the use of some syringe and some immunogenic material.""" ;
rdfs:domain obo:IAO_0000033 ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000589 .
obo:REO_0000589 a rdf:Property ;
rdfs:label "specifies_participation_of" ;
rdfs:comment """relation between some action specification and a material entity whose participation is specified.
Ex: the action specifications outlined in an immunization protocol would specify the participation of some T cell or B cell, but specifies the use of some syringe and some immunogenic material.""" ;
rdfs:domain obo:IAO_0000033 ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000313 .
obo:BFO_0000052 a rdf:Property ;
rdfs:label "inheres in"@en ;
rdfs:comment "A relation between a dependent continuant D and an entity E. D inheres_in E iff: given any d that instantiates D at t, there exists some e that instantiates E at t and d *inheres_in* e at t. Here *inheres_in* is the primitive instance level relation." ;
rdfs:domain ;
rdfs:range .
obo:REO_0000313 a rdf:Property ;
rdfs:label "specifies" ;
rdfs:comment """relation between some action specification and entities it specifies.
These entities can include material entities whose participation or intentional application/use is specified, or processes whose occurrence or intentional execution is specified.""" ;
rdfs:domain obo:IAO_0000033 ;
rdfs:range ;
rdfs:subPropertyOf obo:IAO_0000136 .
obo:REO_0000704 a rdf:Property ;
rdfs:label "has numeric value" ;
rdfs:domain obo:IAO_0000030 ;
rdfs:range xsd:float .
obo:BFO_0000058 a rdf:Property ;
rdfs:label "concretization of"@en ;
rdfs:comment "Is a relationship between a generically dependent continuant and a specifically dependent continuant. A generically dependent continuant may inhere in more than one entity. It does so by virtue of the fact that there is, for each entity that it inheres, a specifically dependent *concretization* of the generically dependent continuant that is specifically dependent. For instance, consider a story, which is an information artifact that inheres in some number of books. Each book bears some quality that carries the story. The relation between this quality and the generically dependent continuant is that the former is the concretization of the latter." ;
rdfs:domain ;
rdfs:range .
obo:REO_0000566 a rdf:Property ;
rdfs:label "has unit label" ;
rdfs:domain obo:IAO_0000030 ;
rdfs:range ;
rdfs:subPropertyOf .
obo:IAO_0000219 a rdf:Property ;
rdfs:label "denotes"@en ;
rdfs:comment "denotes is a primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically"@en ;
rdfs:domain obo:IAO_0000030 ;
rdfs:range ;
rdfs:subPropertyOf obo:IAO_0000136 .
obo:REO_0000544 a rdf:Property ;
rdfs:label "towards" ;
rdfs:comment "a relation between a relational dependent continuant and an independent continuant, that distinguishes the main bearers of the relational dependent continuant from additional dependents." ;
rdfs:domain ;
rdfs:range .
obo:IAO_0000418 a rdf:Property ;
rdfs:label "is quality specification of"@en ;
rdfs:comment "a relation between a data item and a quality of a material entity where the material entity is the specified output of a material transformation which achieves an objective specification that indicates the intended value of the specified quality."@en ;
rdfs:domain obo:IAO_0000005 ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000713 .
obo:REO_0000713 a rdf:Property ;
rdfs:label "is quality information about" ;
rdfs:comment "a relation between an information content entity (a measurement datum or an objective specification) and a quality of a material entity that this information content entity either measures or specifies." ;
rdfs:domain obo:IAO_0000030 ;
rdfs:range ;
rdfs:subPropertyOf obo:IAO_0000136 .
obo:CL_0000525 a rdfs:Class ;
rdfs:label "syncytiotrophoblast cell" ;
rdfs:comment "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy." ;
rdfs:subClassOf obo:CL_0000351 .
obo:SO_0000801 a rdfs:Class ;
rdfs:label "assortment_derived_deficiency_plus_duplication" ;
rdfs:comment "A multi-chromosome aberration generated by reassortment of other aberration components; presumed to have a deficiency and a duplication." ;
rdfs:subClassOf obo:SO_0001504 .
obo:CL_0000900 a rdfs:Class ;
rdfs:label "naive thymus-derived CD8-positive, alpha-beta T cell" ;
rdfs:comment "A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." ;
rdfs:subClassOf obo:CL_0000898 .
a rdfs:Class ;
rdfs:label "dependent_continuant" ;
rdfs:comment "Definition: A continuant [snap:Continuant] that is either dependent on one or other independent continuant [snap:IndependentContinuant] bearers or inheres in or is borne by other entities." ;
rdfs:subClassOf .
obo:NCBITaxon_11786 a rdfs:Class ;
rdfs:label "Murine leukemia virus" ;
rdfs:subClassOf obo:NCBITaxon_11632 .
obo:ERO_0000233 a rdf:Property ;
rdfs:label "model_of" ;
rdfs:comment "Disease or condition for which the organism presents some or all defining characteristics." ;
rdfs:range obo:DOID_4 .
obo:REO_0000088 a rdf:Property ;
rdfs:label "used_to_study"@en ;
rdfs:comment "a relation holding between a continuant (e.g. a reagent) and a biological process it is used to investigate" ;
rdfs:range obo:GO_0008150 .
obo:REO_0000501 a rdfs:Class ;
rdfs:label "monoclonal antibody" ;
rdfs:comment "An antibody reagent produced by clonal hybridoma cells deriving from the fusion of a single activasted B-cell with a neoplastic cell, such that antibodies isolated from such cells are monospecific for a single epitope. A collection of such antibodies has specificity for a single epitopes on its target antigen - versus a collection of 'polyclonal antibodies', which recognize various different epitopes. But at the structural level of the individual molecular reagent, there is of course no distinction between mono- and poly-clonal antibodies." ;
rdfs:subClassOf obo:REO_0000002 , obo:REO_0000690 .
obo:REO_0000091 a rdf:Property ;
rdfs:label "used_to_generate"@en ;
rdfs:comment "a relation that holds between a reagent and a organism, construct, cell culture, or antibody that the reagent is used to generate" ;
rdfs:domain obo:REO_0000000 ;
rdfs:range xsd:string .
obo:REO_0000641 a rdf:Property ;
rdfs:label "created_by" ;
rdfs:comment "a relation between some agent and a processed material that is produced by the agent through some planned process." ;
rdfs:domain obo:OBI_0000047 ;
rdfs:range obo:REO_0000230 .
obo:BFO_0000087 a rdf:Property ;
rdfs:label "has role"@en ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf obo:BFO_0000053 .
obo:REO_0000511 a rdf:Property ;
rdfs:label "recognizes" ;
rdfs:comment "a type of targeting relation reserved to describe the relation between an adaptive immune receptor complex and its antigenic target, as antibodies are generated with the function of targeting a specific antigen. For example, antibody x 'recognizes' antigen y if x interacts with an epitope part of y (above some threshhold affinity), and thereby realizes the binding function of the antibody." ;
rdfs:domain obo:OBI_1110022 ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000823 .
obo:REO_0000823 a rdf:Property ;
rdfs:label "targets" ;
rdfs:comment "a relation between molecular entities, whereby molecular entity x 'targets' molecular entity y if x interacts with y (above some threshhold affinity), and x bears some function or role realized in this interaction that is is created or applied to facilitate. Thus, x has evolved to, been engineered to, or is applied and perceived by some agent to play an 'active' role in facilitating the interaction." ;
rdfs:range .
obo:OBI_0000312 a rdf:Property ;
rdfs:label "is_specified_output_of"@en ;
rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
rdfs:range , obo:REO_0000375 ;
rdfs:subPropertyOf .
obo:RO_0002180 a rdf:Property ;
rdfs:label "has component"@en ;
rdfs:comment "a non-transitive, irreflexive relation between a material entiy and its constituent components based upon a non-overlapping and exhaustive partition, like a protein chain is related to its constituent amino acid monomers. The sortal identity of a compound changes as soon as a single component is added or removed (e.g., when we remove an amino acid from the peptide chain of a protein this might change the over-all nature of the protein)." ;
rdfs:range , obo:REO_0000567 ;
rdfs:subPropertyOf .
obo:BFO_0000085 a rdf:Property ;
rdfs:label "has function"@en ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf obo:BFO_0000053 .
obo:REO_0000862 a rdf:Property ;
rdfs:label "developed_by" ;
rdfs:domain obo:OBI_0000047 ;
rdfs:range obo:REO_0000859 .
obo:REO_0000696 a rdf:Property ;
rdfs:label "has_disposition" ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf obo:BFO_0000053 .
obo:RO_0003001 a rdf:Property ;
rdfs:label "produced by"@en ;
rdfs:range .
obo:REO_0000874 a rdfs:Class ;
rdfs:label "material to be removed role" ;
rdfs:subClassOf obo:REO_0000248 .
obo:BFO_0000059 a rdf:Property ;
rdfs:label "concretizes"@en ;
rdfs:comment "Is a relationship between a specifically dependent continuant and a generically dependent continuant. A generically dependent continuant may inhere in more than one entity. It does so by virtue of the fact that there is, for each entity that it inheres, a specifically dependent *concretization* of the generically dependent continuant that is specifically dependent. For instance, consider a story, which is an information artifact that inheres in some number of books. Each book bears some quality that carries the story. The relation between this quality and the generically dependent continuant is that the former is the concretization of the latter." ;
rdfs:domain ;
rdfs:range .
obo:REO_0000252 a rdf:Property ;
rdfs:label "gained_through" ;
rdfs:comment "a relation holding between a realizable entity and some process through which the role begins to inhere in an independent continuant bearer" ;
rdfs:domain ;
rdfs:range .
obo:CL_0002253 a rdfs:Class ;
rdfs:label "epithelial cell of large intestine" ;
rdfs:comment "An epithelial cell of the large intestine." ;
rdfs:subClassOf obo:CL_0002251 .
obo:REO_0000435 a rdfs:Class ;
rdfs:label "metalloid atomic reagent" ;
rdfs:comment "a metalloid atomic molecular entity that bears a reagent role" ;
rdfs:subClassOf obo:REO_0000284 , obo:REO_0000790 .
a rdf:Property ;
rdfs:label "has_part"@en ;
rdfs:comment "This relation can hold across granularities, such that entities existing at finer levels can be considered (e.g. a cell or organism can have part a protein, small molecule, or atom)" ;
rdfs:range obo:REO_0000432 , obo:REO_0000135 , , obo:CHEBI_25585 , obo:CHEBI_33521 .
obo:CLO_0000003 a rdfs:Class ;
rdfs:label "adherent cell line culturing" ;
rdfs:comment "adherent cell line culturing is a cell line culturing method where cells require a surface for growth and differentiation." ;
rdfs:subClassOf obo:CLO_0000000 .
obo:OBI_0000299 a rdf:Property ;
rdfs:label "has_specified_output"@en ;
rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
rdfs:domain ;
rdfs:range obo:OBI_0000047 , obo:IAO_0000027 , obo:REO_0000007 , obo:IAO_0000030 , ;
rdfs:subPropertyOf obo:RO_0002234 .
obo:OBI_0000417 a rdf:Property ;
rdfs:label "achieves_planned_objective" ;
rdfs:comment "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process." ;
rdfs:domain obo:OBI_0000011 ;
rdfs:range obo:IAO_0000005 , obo:OBI_0000678 , obo:OBI_0000796 ;
rdfs:subPropertyOf obo:REO_0000335 .
obo:REO_0000328 a rdf:Property ;
rdfs:label "execution_specified_by" ;
rdfs:comment "a relation holding between a planned process and a directive information entity that specifies the performance of this process by some agent" ;
rdfs:domain obo:OBI_0000011 ;
rdfs:range obo:IAO_0000033 ;
rdfs:subPropertyOf obo:REO_0000590 .
obo:REO_0000335 a rdf:Property ;
rdfs:label "achieves_specification" ;
rdfs:domain obo:OBI_0000011 ;
rdfs:range obo:IAO_0000033 .
obo:OBI_0000293 a rdf:Property ;
rdfs:label "has_specified_input"@en ;
rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
rdfs:domain ;
rdfs:range , obo:IAO_0000027 , ;
rdfs:subPropertyOf obo:RO_0002233 .
a rdf:Property ;
rdfs:label "has_agent"@en ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf .
obo:REO_0000337 a rdf:Property ;
rdfs:label "achieves_plan_specification" ;
rdfs:comment "According to OBI, this could be a shortcut relation for 'realizes some (concretizes some 'plan specification'). But as noted in feedback annotaitn, I have concerns about the use of the 'realizes' relation in this way." ;
rdfs:domain obo:OBI_0000011 ;
rdfs:range obo:IAO_0000104 ;
rdfs:subPropertyOf obo:REO_0000335 .
obo:NCBITaxon_5207 a rdfs:Class ;
rdfs:label "Cryptococcus neoformans" ;
rdfs:subClassOf obo:NCBITaxon_4751 .
obo:CL_0002037 a rdfs:Class ;
rdfs:label "CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell" ;
rdfs:comment "Intraepithelial T cells with a memory phenotype of CD2-positive, CD5-positive, and CD44-positive." ;
rdfs:subClassOf obo:CL_0000793 .
obo:REO_0000099 a rdfs:Class ;
rdfs:label "primer pair"@en ;
rdfs:comment "a reagent comprised of two primers that are complementary to a specified stretch of nucleic acid sequence, and used in a polymerase chain reaction to amplify this segment of nucleic acid" ;
rdfs:subClassOf obo:REO_0000000 , .
obo:REO_0000728 a rdf:Property ;
rdfs:label "has aggregate part" ;
rdfs:comment "a non-transitive, irreflexive has_part relation between a collection or object aggregate and an object that is an individual, separable part of the collection" ;
rdfs:range obo:REO_0000514 , obo:CHEBI_23367 ;
rdfs:subPropertyOf .
obo:NCBITaxon_666 a rdfs:Class ;
rdfs:label "Vibrio cholerae" ;
rdfs:subClassOf obo:NCBITaxon_2 .
obo:REO_0000365 a rdfs:Class ;
rdfs:label "obsolete_cell modification objective" ;
rdfs:subClassOf .
obo:NCBITaxon_12058 a rdfs:Class ;
rdfs:label "Picornaviridae" ;
rdfs:subClassOf obo:NCBITaxon_10239 .
obo:CHEBI_16467 a rdfs:Class ;
rdfs:label "L-arginine" ;
rdfs:comment "An L-alpha-amino acid that is the L-isomer of arginine." ;
rdfs:subClassOf obo:REO_0000545 .
obo:BFO_0000086 a rdf:Property ;
rdfs:label "has quality"@en ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf obo:BFO_0000053 .
obo:REO_0000885 a rdfs:Class ;
rdfs:label "green fluorescent protein reagent" ;
rdfs:subClassOf obo:REO_0000291 , obo:REO_0000691 , obo:REO_0000864 .
obo:REO_0000117 a rdf:Property ;
rdfs:label "has_entrez_gene_symbol"@en ;
rdfs:comment "Note that the information macromolecule need not contain the entire sequence held in the entrez gene record, but only a significant portion of it." ;
rdfs:range xsd:string .
obo:REO_0000833 a rdf:Property ;
rdfs:label "genetically_derives_from" ;
rdfs:comment "a relation between sequence molecules (DNA, RNA, protein) wherein one serves as a template for the transmission of genetic information through the processes of transcription and translation (specifically, DNA or RNA to RNA or protein)." ;
rdfs:range xsd:string .
obo:REO_0000906 a rdf:Property ;
rdfs:label "has_monomeric_unit" ;
rdfs:range obo:CHEBI_33708 , obo:REO_0000456 , obo:REO_0000817 , obo:REO_0000838 , obo:REO_0000513 ;
rdfs:subPropertyOf obo:RO_0002180 .
obo:REO_0000866 a rdf:Property ;
rdfs:label "translated_from" ;
rdfs:comment """shortcut relation for:
is_output_of (translation and (realizes some ('information template role' and ('inheres in' some RNA))))""" ;
rdfs:domain obo:PR_000000001 ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:REO_0000833 .
obo:REO_0000114 a rdf:Property ;
rdfs:label "has_entrez_gene_id"@en ;
rdfs:comment "relates an amino acid chain or nucleic acid or SO:region to an entrez_gene record that describes a sequence that is represented in the sequence of the amino acid chain, nucleic acid, or region. " ;
rdfs:range xsd:string .
obo:REO_0000784 a rdfs:Class ;
rdfs:label "student role" ;
rdfs:subClassOf obo:REO_0000700 .
obo:BFO_0000054 a rdf:Property ;
rdfs:label "is realized by"@en ;
rdfs:range , obo:OBI_0001152 , obo:OBI_0000685 , obo:OBI_0000443 , obo:OBI_0600064 , obo:OBI_0000070 , obo:OBI_0000471 .
obo:NCBITaxon_12333 a rdfs:Class ;
rdfs:label "unclassified phages" ;
rdfs:subClassOf obo:NCBITaxon_10239 .
obo:OBI_0000094 a rdfs:Class ;
rdfs:label "material processing"@en ;
rdfs:comment "A planned process which results in physical changes in a specified input material"@en ;
rdfs:subClassOf obo:OBI_0000011 .
obo:NCBITaxon_8400 a rdfs:Class ;
rdfs:label "Rana catesbeiana" ;
rdfs:subClassOf obo:NCBITaxon_8342 .
obo:SO_0001218 a rdfs:Class ;
rdfs:label "transgenic_insertion" ;
rdfs:comment "An insertion that derives from another organism, via the use of recombinant DNA technology." ;
rdfs:subClassOf obo:SO_0000667 .
obo:CARO_0000043 a rdfs:Class ;
rdfs:label "portion of tissue" ;
rdfs:comment "Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships." ;
rdfs:subClassOf obo:CARO_0000003 .
obo:REO_0000846 a rdfs:Class ;
rdfs:label "obsolete_cytidine" ;
rdfs:subClassOf .
obo:GO_0005488 a rdfs:Class ;
rdfs:label "binding" ;
rdfs:comment "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf .
obo:CL_0000036 a rdfs:Class ;
rdfs:label "epithelial fate stem cell" ;
rdfs:subClassOf obo:CL_0000035 .
obo:REO_0000324 a rdfs:Class ;
rdfs:label "obsolete_indicator reagent" ;
rdfs:comment "a molecular entity that is able to generate a detectable signal, and is intended to be used as a proxy for measuring some relative characteristic of an analyte in an analyte assay (e.g. its presence in, abundance in, location in, or processing by some evaluant), or for the activity of an evaluant in an activity assay." ;
rdfs:subClassOf obo:REO_0000982 .
obo:CL_0000896 a rdfs:Class ;
rdfs:label "activated CD4-positive, alpha-beta T cell" ;
rdfs:comment "A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive." ;
rdfs:subClassOf obo:CL_0000624 .
obo:CL_0002014 a rdfs:Class ;
rdfs:label "Kit-negative, Ly-76 high basophilic erythroblast" ;
rdfs:comment "A basophilic erythroblast that is Lyg 76-high and is Kit-negative." ;
rdfs:subClassOf obo:CL_0000549 .
obo:NCBITaxon_95486 a rdfs:Class ;
rdfs:label "Burkholderia cenocepacia" ;
rdfs:subClassOf obo:NCBITaxon_32008 .
obo:CL_0000192 a rdfs:Class ;
rdfs:label "smooth muscle cell" ;
rdfs:comment "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." ;
rdfs:subClassOf obo:CL_0000187 .
obo:REO_0000045 a rdfs:Class ;
rdfs:label "complementary DNA"@en ;
rdfs:comment "a DNA moelcule representing sequence reverse transcribed from a messenger RNA template, in a reaction catalyzed by the enzyme reverse transcriptase and the enzyme DNA polymerase." ;
rdfs:subClassOf obo:CHEBI_16991 .
obo:REO_0000886 a rdf:Property ;
rdfs:label "genetically_derived_into" ;
rdfs:comment "a relation between a nucleic acid or mRNA molecule and an RNA or protein molecule for which it serves as a template for transmission of genetic information through the processes of transcription and translation." ;
rdfs:range xsd:string .
obo:NCBITaxon_7778 a rdfs:Class ;
rdfs:label "Elasmobranchii" ;
rdfs:subClassOf obo:NCBITaxon_7777 .
obo:OBI_0000268 a rdfs:Class ;
rdfs:label "organism feature identification objective"@en ;
rdfs:comment "Organism_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the level of the organism, e.g. height, weight, stage of development, stage of life cycle."@en ;
rdfs:subClassOf obo:OBI_0000015 .
obo:REO_0000582 a rdfs:Class ;
rdfs:label "obsolete_epitope binding by adaptive immune receptor" ;
rdfs:comment "is the process in which an adaptive immune receptor binds to a material entity (realizing its disposition). The binding affinity is significant enough to trigger an immune response. Specifically, transient non-specific binding of adaptive immune receptors occurring during immune surveillance is not considered significant binding." ;
rdfs:subClassOf .
obo:CARO_0000050 a rdfs:Class ;
rdfs:label "protogynous hermaphroditic organism" ;
rdfs:comment "Sequential hermaphroditic organism that produces\\ngametes first of the female sex, and then later of the\\nmale sex." ;
rdfs:subClassOf obo:CARO_0000045 .
obo:NCBITaxon_10404 a rdfs:Class ;
rdfs:label "Hepadnaviridae" ;
rdfs:subClassOf obo:NCBITaxon_10239 .
obo:CL_0000425 a rdfs:Class ;
rdfs:label "pore cell" ;
rdfs:comment "Forms the terminal part of the cuticle-lined excretory duct of C. elegans." ;
rdfs:subClassOf obo:CL_0000658 .
obo:REO_0000205 a rdfs:Class ;
rdfs:label "molecular target role" ;
rdfs:comment "a role inhereing in a molecular entity that is specifically bound by some molecular probe (e.g. a molecular label, a chemical inhibitor) in the process of some assay or material processing technique." ;
rdfs:subClassOf obo:REO_0000248 .
obo:CL_0000992 a rdfs:Class ;
rdfs:label "immature CD11c-low plasmacytoid dendritic cell" ;
rdfs:comment "Immature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD80-low and CD86-low." ;
rdfs:subClassOf obo:CL_0000989 .
obo:CL_0000704 a rdfs:Class ;
rdfs:label "endothelial tip cell" ;
rdfs:comment "A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels." ;
rdfs:subClassOf obo:CL_0000071 .
obo:CL_0000200 a rdfs:Class ;
rdfs:label "touch receptor cell" ;
rdfs:subClassOf obo:CL_0000199 .
obo:UBERON_0000070 a rdfs:Class ;
rdfs:label "pupal stage" ;
rdfs:comment "A life stage of some insects undergoing transformation. The pupal stage is found only in holometabolous insects, those that undergo a complete metamorphosis, going through four life stages; embryo, larva, pupa and imago." ;
rdfs:subClassOf obo:UBERON_0000092 .
a rdf:Property ;
rdfs:label "precedes"@en ;
rdfs:domain ;
rdfs:range .
a rdf:Property ;
rdfs:label "has_participant"@en ;
rdfs:comment "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time." ;
rdfs:domain ;
rdfs:range .
a rdf:Property ;
rdfs:label "preceded_by"@en ;
rdfs:comment "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other." ;
rdfs:domain ;
rdfs:range .
a rdf:Property ;
rdfs:domain ;
rdfs:range ;
rdfs:subPropertyOf .
obo:REO_0000387 a rdfs:Class ;
rdfs:label "experimentally modified unicellular organism in environment" ;
rdfs:comment "an experimentally modified unicellular organism that is found in a native setting (i.e. in a natural environment, and not re-located by some intentional agent to a controlled artificial setting for use in some investigation or study)" ;
rdfs:subClassOf obo:REO_0000363 , obo:REO_0000521 .
obo:CL_0000598 a rdfs:Class ;
rdfs:label "pyramidal cell" ;
rdfs:comment "A projection neuron in the cerebral cortex and the hippocampus. Pyramidal cells have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their cortical region." ;
rdfs:subClassOf obo:CL_0000117 .
obo:CHEBI_29236 a rdfs:Class ;
rdfs:label "protium atom" ;
rdfs:comment "The stable isotope of hydrogen with relative atomic mass 1.007825 and a natural abundance of 99.9885 atom percent (from Greek pirhoomegatauomicronsigma, first)." ;
rdfs:subClassOf obo:CHEBI_49637 .
obo:OBI_0200081 a rdfs:Class ;
rdfs:label "sequence analysis objective"@en ;
rdfs:comment "A sequence analysis objective is a data transformation objective which aims to analyse some ordered biological data for sequential patterns."@en ;
rdfs:subClassOf obo:OBI_0200166 .
obo:NCBITaxon_30640 a rdfs:Class ;
rdfs:label "Sciurus carolinensis" ;
rdfs:subClassOf obo:NCBITaxon_9989 .
obo:SO_0000512 a rdfs:Class ;
rdfs:label "inversion_derived_deficiency_plus_aneuploid" ;
rdfs:comment "A chromosomal deletion whereby a chromosome generated by recombination between two inversions; has a deficiency at one end and presumed to have a deficiency or duplication at the other end of the inversion." ;
rdfs:subClassOf obo:SO_1000029 .
obo:REO_0000332 a rdfs:Class ;
rdfs:label "obsolete_fluorescent stain role" ;
rdfs:subClassOf .
obo:REO_0000334 a rdfs:Class ;
rdfs:label "molecular tracker" ;
rdfs:comment "a molecular label that is not capable of producing a detectable signal" ;
rdfs:subClassOf obo:CHEBI_23367 , obo:REO_0000280 .
obo:CL_0002351 a rdfs:Class ;
rdfs:label "progenitor cell of endocrine pancreas" ;
rdfs:comment "A multi-fate stem cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 andĀ Isl-1." ;
rdfs:subClassOf obo:CL_0000048 .
obo:REO_0000605 a rdfs:Class ;
rdfs:label "IgG1 immunoglobulin complex, circulating" ;
rdfs:subClassOf obo:GO_0042571 .
obo:CHEBI_50308 a rdfs:Class ;
rdfs:label "CMP residue" ;
rdfs:subClassOf obo:CHEBI_50299 .
obo:REO_0000137 a rdf:Property ;
rdfs:label "is component part of"@en ;
rdfs:comment "Inverse of has_component, for use in recording part_of with a cardinality constraint." ;
rdfs:range ;
rdfs:subPropertyOf .
obo:REO_0000907 a rdf:Property ;
rdfs:label "is_monomeric_unit_of" ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000137 .
a rdf:Property ;
rdfs:label "is substituent group from" ;
rdfs:comment """Indicates the relationship between a substituent group (or atom) and its parent molecular entity, from which it is formed by loss of one or more protons or simple groups such as hydroxy groups. E.g.
Definition: A is_substituent_group_from B if and only if A is a group and B is a molecular entity; given any a that instantiates A, a has molecular graph ag and specified attachment point agap, and there is some b that instantiates B and has molecular graph bg, then it is the case that bg is the result of a graph transformation process on ag resulting in the replacement of agap by some group bgg (which may be a hydrogen atom or a more complex group).""" ;
rdfs:range .
obo:REO_0000631 a rdfs:Class ;
rdfs:label "IgD monoclonal antibody reagent" ;
rdfs:subClassOf obo:REO_0000501 , obo:REO_0000612 .
obo:SO_0000207 a rdfs:Class ;
rdfs:label "simple_sequence_length_variation" ;
rdfs:subClassOf obo:SO_0000248 .
obo:CL_0000961 a rdfs:Class ;
rdfs:label "Bm1 B cell" ;
rdfs:comment "A follicular B cell that expresses IgD, but not CD23 or CD38. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells." ;
rdfs:subClassOf obo:CL_0000843 .
obo:REO_0000424 a rdfs:Class ;
rdfs:label "DNA oligonucleotide reagent" ;
rdfs:comment "a DNA reagent consisting of a short, linear string of typically 100 or fewer nucleotides" ;
rdfs:subClassOf obo:REO_0000030 , obo:REO_0000031 .
obo:CL_0000863 a rdfs:Class ;
rdfs:label "inflammatory macrophage" ;
rdfs:comment "An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity." ;
rdfs:subClassOf obo:CL_0000861 .
obo:CL_0002148 a rdfs:Class ;
rdfs:label "dental pulp cell" ;
rdfs:comment "A cell found within the dental pulp." ;
rdfs:subClassOf obo:CL_0002159 .
obo:CL_0001002 a rdfs:Class ;
rdfs:label "mature CD8_alpha-negative CD11b-negative dendritic cell" ;
rdfs:comment "Mature CD8_alpha-negative CD11b-negative dendritic cell is a CD8_alpha-negative CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive." ;
rdfs:subClassOf obo:CL_0000998 .
a rdfs:Class ;
rdfs:label "temporal_region" ;
rdfs:comment "Comment: Time and temporal region [span:TemporalRegion] entities are entities in their own rights which exist independently of any entities which can be located at them. This view of time can be called \"absolutist\" or \"the container view\" in analogy to what is traditionally the case with space (see spatial region [snap:SpatialRegion]." ;
rdfs:subClassOf .
obo:CL_1000082 a rdfs:Class ;
rdfs:label "stretch receptor cell" ;
rdfs:subClassOf obo:CL_0000006 .
obo:REO_0000709 a rdfs:Class ;
rdfs:label "obsolete_inputting of a material participant" ;
rdfs:subClassOf .
obo:REO_0000200 a rdfs:Class ;
rdfs:label "interleukin-3 reagent"@en ;
rdfs:subClassOf obo:REO_0000840 .
obo:CL_0000806 a rdfs:Class ;
rdfs:label "DN2 thymocyte" ;
rdfs:comment "A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive." ;
rdfs:subClassOf obo:CL_0000893 .
obo:CL_0000126 a rdfs:Class ;
rdfs:label "macroglial cell" ;
rdfs:comment "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together." ;
rdfs:subClassOf obo:CL_0000243 .
obo:REO_0000124 a rdfs:Class ;
rdfs:label "primer library"@en ;
rdfs:comment "a nucleic acid library consisting of a collection of primers, stored as uniform aliquots of primers of a given sequence used for amplification of target nucleic acid sequences." ;
rdfs:subClassOf obo:REO_0000768 .
obo:REO_0000178 a rdfs:Class ;
rdfs:label "covalent reporter role"@en ;
rdfs:comment "a molecular reporter role inhering in a molecular entity that is capable of producing a detectable signal, but not capable of autonomous non-covalent association with a molecular target (such that it must be covalenly attached to an analyte of interest, or to a targeted molecular label that can direct it to an analyte)." ;
rdfs:subClassOf obo:REO_0000339 .
obo:ERO_0000581 a rdfs:Class ;
rdfs:label "Prokaryota" ;
rdfs:subClassOf obo:CARO_0000064 , obo:NCBITaxon_131567 .
obo:CL_0000756 a rdfs:Class ;
rdfs:label "type 4 cone bipolar cell (sensu Mus)" ;
rdfs:comment "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell has a diffuse axon terminal with varicosities in sublaminae 1 and 2 of the inner plexiform layer." ;
rdfs:subClassOf obo:CL_0000752 .
obo:CL_0002234 a rdfs:Class ;
rdfs:label "basal cell of prostatic acinus" ;
rdfs:comment "A cell of the basal layer of the epithelium in the prostatic acinus." ;
rdfs:subClassOf obo:CL_0002341 .
obo:CL_0000911 a rdfs:Class ;
rdfs:label "effector T cell" ;
rdfs:comment "A differentiated T cell with ability to traffic to peripheral tissues and is capable of mounting a specific immune response." ;
rdfs:subClassOf obo:CL_0002419 .
a rdfs:Class ;
rdfs:label "fiat_object_part" ;
rdfs:comment "Definition: A material entity [snap:MaterialEntity] that is part of an object [snap:Object] but is not demarcated by any physical discontinuities." ;
rdfs:subClassOf .
obo:REO_0000539 a rdfs:Class ;
rdfs:label "obsoelte_polar polarity" ;
rdfs:comment "A molecular quality that inheres in a molecular entity by virtue of the bearer exhibiting a separation of electric charge which leads to the it having an electric dipole." ;
rdfs:subClassOf obo:REO_0000537 .
obo:CL_0000205 a rdfs:Class ;
rdfs:label "thermoreceptor cell" ;
rdfs:comment "A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain." ;
rdfs:subClassOf obo:CL_0000006 .
obo:REO_0000463 a rdfs:Class ;
rdfs:label "antibody production" ;
rdfs:comment "a material processing technique with the goal of generating antibody reagents for applicaiton in some scientific technique. This is a multi-step process that requires immunization of some organism to activate the adaptive immune response, and collection of antibodies either from the immunized organism directly, of from hybridoma cells that are generated by fusing activated B-cells from the immunized organism with myeloma cells" ;
rdfs:subClassOf obo:REO_0000159 .
obo:REO_0000989 a rdfs:Class ;
rdfs:label "establishing biomaterial culture" ;
rdfs:comment "a process which results in creating an in vitro environment in which some virus or cell-based biomaterial (cells, tissue, organisms) is sustained " ;
rdfs:subClassOf obo:REO_0000575 .
obo:IAO_0000009 a rdfs:Class ;
rdfs:label "label"@en ;
rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:CL_0002048 a rdfs:Class ;
rdfs:label "late pro-B cell" ;
rdfs:comment "A pre-B cell precursor is CD19-low, CD22-positive , CD34-positive, CD38-positive." ;
rdfs:subClassOf obo:CL_0000817 .
obo:CL_0001009 a rdfs:Class ;
rdfs:label "immature dermal dendritic cell" ;
rdfs:comment "Immature dermal dendritic cell is a dermal dendritic cell that is CD80-low, CD86-low, and MHCII-low." ;
rdfs:subClassOf obo:CL_0001006 .
obo:REO_0000372 a rdfs:Class ;
rdfs:label "obsolete_cultured multicellular organism cell" ;
rdfs:comment "a multicellular organism cell that is maintained (propagated or held metabolically active) in vitro as part of a cell culture" ;
rdfs:subClassOf .
obo:IAO_0000443 a rdfs:Class ;
rdfs:label "data item extraction from journal article" ;
rdfs:comment "a planned process in which journal articles are read or processed and data items are extracted, typically for further analysis or indexing" ;
rdfs:subClassOf obo:IAO_0000027 .
obo:CHEBI_36936 a rdfs:Class ;
rdfs:label "nitrogen-16 atom" ;
rdfs:subClassOf obo:CHEBI_25555 .
obo:CL_0002398 a rdfs:Class ;
rdfs:label "Gr1-positive, CD43-positive monocyte" ;
rdfs:comment "An intermediate monocyte that is Gr1-positive, CD43-positive." ;
rdfs:subClassOf obo:CL_0002393 .
obo:REO_0000668 a rdfs:Class ;
rdfs:label "obsolete_material decontamination objective" ;
rdfs:subClassOf .
obo:REO_0000215 a rdfs:Class ;
rdfs:label "obsolete_specimen collection" ;
rdfs:comment "a material collection technique in which some material is obtained form its natural environment as an example of some class of material entity. Specimens are often used as input into some assay or material processing technique as part of an investigation." ;
rdfs:subClassOf .
obo:SO_0000704 a rdfs:Class ;
rdfs:label "gene" ;
rdfs:comment "A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions." ;
rdfs:subClassOf obo:REO_0000079 .
obo:REO_0000868 a rdf:Property ;
rdfs:label "sequence_derives_from" ;
rdfs:comment "relation between two genetic sequence regions (GDCs) that describes the 'mapping' of genetic sequence information from RNA sequence to DNA sequence, amino acid sequence to RNA sequence, or amino acid sequence ot DNA sequence" ;
rdfs:range obo:REO_0000714 .
obo:REO_0000887 a rdf:Property ;
rdfs:label "sequence_derives_into" ;
rdfs:comment "relation between two genetic sequence regions (GDCs) that describes the 'mapping' of genetic sequence information from DNA sequence to RNA sequence, RNA sequence to amino acid sequence, or DNA to amino acid sequence" ;
rdfs:domain obo:REO_0000714 ;
rdfs:range xsd:string .
obo:CL_0002324 a rdfs:Class ;
rdfs:label "myoepithelial cell of mammary gland" ;
rdfs:comment "A myoepithelial cell that surrounds milk-secreting luminal epithelial cells. This cell type contracts under the stimulation of oxytocin and is attached to the basement membrane by hemidesmosomes and to the adjacent luminal cells by desmosomes. This cell type expresses high level of keratin-14 and is estrogen receptor alpha negative." ;
rdfs:subClassOf obo:CL_0002327 .
obo:REO_0000690 a rdfs:Class ;
rdfs:label "bioengineered protein reagent" ;
rdfs:subClassOf obo:REO_0000858 .
obo:REO_0000113 a rdfs:Class ;
rdfs:label "obsolete_in vitro cell morphology"@en ;
rdfs:subClassOf .
obo:OBI_0001331 a rdfs:Class ;
rdfs:label "transcription profiling identification objective"@en ;
rdfs:comment "A molecular feature identification objective that aims to characterize the abundance of transcripts"@en ;
rdfs:subClassOf obo:OBI_0000131 .
obo:CL_0000075 a rdfs:Class ;
rdfs:label "columnar/cuboidal epithelial cell" ;
rdfs:subClassOf obo:CL_0000066 .
obo:NCBITaxon_632 a rdfs:Class ;
rdfs:label "Yersinia pestis" ;
rdfs:subClassOf obo:NCBITaxon_2 .
obo:CL_0000402 a rdfs:Class ;
rdfs:label "CNS interneuron" ;
rdfs:subClassOf obo:CL_0000117 .
obo:IAO_0000313 a rdfs:Class ;
rdfs:label "patent"@en ;
rdfs:comment "A document that has been accepted by a patent authority"@en ;
rdfs:subClassOf obo:IAO_0000310 .
obo:REO_0000528 a rdfs:Class ;
rdfs:label "unmodified unicellular organism in environment" ;
rdfs:comment "an unmodified unicellular organism that is part of a native setting (i.e. in a natural environment, and not re-located by some intentional agent to a controlled artificial setting for use in some investigation or study)" ;
rdfs:subClassOf obo:REO_0000530 , obo:REO_0000701 .
obo:CL_0000148 a rdfs:Class ;
rdfs:label "melanocyte" ;
rdfs:comment "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance." ;
rdfs:subClassOf obo:CL_0000710 .
obo:OBI_0200183 a rdfs:Class ;
rdfs:label "scaling objective"@en ;
rdfs:comment "is a data transformation objective where all, or some of a data set is adjusted by some data transformation according to some scale, for example a user defined minimum or maximum" ;
rdfs:subClassOf obo:OBI_0200166 .
obo:MOD_00045 a rdfs:Class ;
rdfs:label "3'-phospho-L-histidine" ;
rdfs:comment "A protein modification that effectively converts an L-histidine residue to pros-phospho-L-histidine (N-pi-phospho-L-histidine, 3'-phospho-L-histidine)." ;
rdfs:subClassOf obo:MOD_00696 .
obo:CL_0000885 a rdfs:Class ;
rdfs:label "gut-associated lymphoid tissue macrophage" ;
rdfs:comment "A mucosa-associated lymphoid tissue macrophage found in the mucosa-associated lymphoid tissues of the gut." ;
rdfs:subClassOf obo:CL_0000884 .
obo:NCBITaxon_10088 a rdfs:Class ;
rdfs:label "Mus" ;
rdfs:subClassOf obo:NCBITaxon_9989 .
obo:MOD_01150 a rdfs:Class ;
rdfs:label "neddylated lysine" ;
rdfs:comment "A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a nedd8 protein." ;
rdfs:subClassOf obo:PR_000025513 .
obo:IAO_0000055 a rdfs:Class ;
rdfs:label "rule"@en ;
rdfs:comment "a rule is an executable which guides, defines, restricts actions"@en ;
rdfs:subClassOf obo:IAO_0000001 .
obo:PATO_0002188 a rdfs:Class ;
rdfs:label "nonpolar polarity" ;
rdfs:comment "A molecular quality which inheres in a molecular entity when the molecular entity does not possess an electrical dipole." ;
rdfs:subClassOf obo:PATO_0002186 .
obo:REO_0000732 a rdf:Property ;
rdfs:label "has quality value" ;
rdfs:comment "range is a string so that units can be recorded as part of a numeric value" ;
rdfs:domain ;
rdfs:range xsd:string .
obo:REO_0000705 a rdf:Property ;
rdfs:label "is quality described by" ;
rdfs:domain ;
rdfs:range obo:IAO_0000030 .
obo:REO_0000496 a rdf:Property ;
rdfs:label "is quality specified as" ;
rdfs:domain ;
rdfs:range obo:REO_0000497 ;
rdfs:subPropertyOf obo:REO_0000705 .
obo:IAO_0000417 a rdf:Property ;
rdfs:label "is quality measured as"@en ;
rdfs:comment "inverse of the relation of is quality measurement of"@en ;
rdfs:domain ;
rdfs:range obo:IAO_0000109 ;
rdfs:subPropertyOf obo:REO_0000705 .
obo:SO_0001025 a rdfs:Class ;
rdfs:label "polymorphic_sequence_variant" ;
rdfs:comment "A sequence variant that is segregating in one or more natural populations of a species." ;
rdfs:subClassOf obo:SO_0001023 .
obo:CL_0005011 a rdfs:Class ;
rdfs:label "renal alpha-intercalated cell" ;
rdfs:comment "A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs base to regulate acid/base balance." ;
rdfs:subClassOf obo:CL_0005010 .
obo:CL_0000100 a rdfs:Class ;
rdfs:label "motor neuron" ;
rdfs:comment "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." ;
rdfs:subClassOf obo:CL_0000527 .
obo:REO_0000620 a rdfs:Class ;
rdfs:label "IgG2a polyclonal antibody reagent" ;
rdfs:subClassOf .
obo:REO_0000157 a rdfs:Class ;
rdfs:label "transgenic material"@en ;
rdfs:comment "a material entity, arising from an organism, cell, or cell line, which has been modified through some transgenic technique to contain exogenous genetic material from a different cell or organism (i.e. genetic material that is not normally part of the target material)" ;
rdfs:subClassOf obo:OBI_0001151 .
obo:ERO_0001193 a rdfs:Class ;
rdfs:label "transgenic adeno-associated virus" ;
rdfs:comment "A transgenic virus derived from an andeno-associated virus that is engineered to serve as a vehicle to carry foreign genetic material, which it can transfer into cells or organisms." ;
rdfs:subClassOf obo:ERO_0001188 .
obo:SO_1000010 a rdfs:Class ;
rdfs:label "pyrimidine_transition" ;
rdfs:comment "A substitution of a pyrimidine, C or T, for another pyrimidine." ;
rdfs:subClassOf obo:SO_1000009 .
obo:OBI_0600060 a rdfs:Class ;
rdfs:label "DNA transfection"@en ;
rdfs:comment "a transfection which relies on the use of physical, electrical and chemical phenomena to introduce DNA into a cell"@en ;
rdfs:subClassOf obo:OBI_0001152 .
obo:REO_0000563 a rdfs:Class ;
rdfs:label "obsolete_endogenously-produced" ;
rdfs:comment "a quality inhering in a biolgocial material that is output of a naturally occuring biological process (ie one that occurs in nature without human intention)" ;
rdfs:subClassOf .
obo:REO_0000978 a rdfs:Class ;
rdfs:label "natural organic small molecule reagent" ;
rdfs:comment "a chemical reagent that is an organic small molecule that is 'natural', in that it exhibits a structure that is found in nature. Such molecules can be isolated from natural sources, or produced through some directed chemical synthesis or engineering technique." ;
rdfs:subClassOf obo:REO_0000446 , obo:REO_0000977 .
obo:NCBITaxon_7509 a rdfs:Class ;
rdfs:label "Siphonaptera" ;
rdfs:subClassOf obo:NCBITaxon_50557 .
obo:CHEBI_17188 a rdfs:Class ;
rdfs:label "nucleoside monophosphate" ;
rdfs:subClassOf obo:CHEBI_25608 .
obo:REO_0000657 a rdfs:Class ;
rdfs:label "obsolete_selected material role" ;
rdfs:subClassOf obo:REO_0000651 .
obo:REO_0000568 a rdfs:Class ;
rdfs:label "obsolete_solvent reagent" ;
rdfs:comment "a solvent that bears a reagent role" ;
rdfs:subClassOf .
obo:CHEBI_30015 a rdfs:Class ;
rdfs:label "L-valine residue" ;
rdfs:subClassOf obo:CHEBI_33700 .
obo:SO_0000183 a rdfs:Class ;
rdfs:label "non_transcribed_region" ;
rdfs:comment "A region of the gene which is not transcribed." ;
rdfs:subClassOf obo:SO_0000842 .
obo:OBI_0200172 a rdfs:Class ;
rdfs:label "partitioning objective"@en ;
rdfs:comment "A partitioning objective is a data transformation objective where the aim is to generate a collection of disjoint non-empty subsets whose union equals a non-empty input set."@en ;
rdfs:subClassOf obo:OBI_0200166 .
obo:IAO_0000416 a rdfs:Class ;
rdfs:label "time measurement datum"@en ;
rdfs:comment "A scalar measurement datum that is the result of measuring a temporal interval"@en ;
rdfs:subClassOf obo:IAO_0000032 .
obo:IAO_0000004 a rdf:Property ;
rdfs:label "has measurement value"@en ;
rdfs:domain obo:IAO_0000032 ;
rdfs:range xsd:float ;
rdfs:subPropertyOf obo:REO_0000704 .
obo:IAO_0000039 a rdf:Property ;
rdfs:label "has measurement unit label"@en ;
rdfs:domain obo:IAO_0000032 ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000566 .
obo:IAO_0000221 a rdf:Property ;
rdfs:label "is quality measurement of"@en ;
rdfs:comment "a relation between a measurement datum and a quality of a material entity that this datum measures." ;
rdfs:domain obo:IAO_0000109 ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000713 .
obo:CL_0000485 a rdfs:Class ;
rdfs:label "mucosal type mast cell" ;
rdfs:comment "Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype." ;
rdfs:subClassOf obo:CL_0000097 .
obo:REO_0000354 a rdfs:Class ;
rdfs:label "tissue microarray" ;
rdfs:comment "a microarray that consists of paraffin blocks in which up to multiple separate tissue cores are assembled in array fashion to allow multiplex histological analysis" ;
rdfs:subClassOf obo:OBI_0400147 .
obo:NCBITaxon_4932 a rdfs:Class ;
rdfs:label "Saccharomyces cerevisiae" ;
rdfs:subClassOf obo:NCBITaxon_4751 .
obo:CL_0002137 a rdfs:Class ;
rdfs:label "type III cell of adrenal cortex" ;
rdfs:comment "A cell in the zona reticularis that produce sex hormones." ;
rdfs:subClassOf obo:CL_0002097 .
obo:REO_0000402 a rdfs:Class ;
rdfs:label "unpassaged mortal cell culture" ;
rdfs:comment "a mortal cell culture that has not been passaged" ;
rdfs:subClassOf obo:CLO_0000018 , obo:REO_0000480 .
obo:OBI_0000643 a rdf:Property ;
rdfs:label "has grain" ;
rdfs:comment "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car." ;
rdfs:range obo:REO_0000131 , obo:REO_0000158 , obo:CARO_0000064 , obo:REO_0000121 ;
rdfs:subPropertyOf .
obo:CL_0002189 a rdfs:Class ;
rdfs:label "granular cell of epidermis" ;
rdfs:comment "A keratinocyte of the epidermis that is characterized by containing granules of keratohyalin and lamellar granules." ;
rdfs:subClassOf obo:CL_0000312 .
obo:CL_0000767 a rdfs:Class ;
rdfs:label "basophil" ;
rdfs:comment "Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive." ;
rdfs:subClassOf obo:CL_0000094 .
obo:NCBITaxon_9913 a rdfs:Class ;
rdfs:label "Bos taurus" ;
rdfs:subClassOf obo:NCBITaxon_40674 .
obo:NCBITaxon_7711 a rdfs:Class ;
rdfs:label "Chordata" ;
rdfs:subClassOf obo:NCBITaxon_131567 .
obo:CL_0002346 a rdfs:Class ;
rdfs:label "Dx5-negative, NK1.1-positive immature natural killer cell" ;
rdfs:comment "An immature natural killer cell that is NK1.1-positive and DX-5 negative." ;
rdfs:subClassOf obo:CL_0000823 .
obo:NCBITaxon_6535 a rdfs:Class ;
rdfs:label "Helix aspersa" ;
rdfs:subClassOf obo:NCBITaxon_6448 .
obo:CL_0000831 a rdfs:Class ;
rdfs:label "mast cell progenitor" ;
rdfs:comment "A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative." ;
rdfs:subClassOf obo:CL_0000839 .
obo:REO_0000452 a rdfs:Class ;
rdfs:comment "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." ;
rdfs:subClassOf obo:REO_0000450 .
obo:NCBITaxon_6239 a rdfs:Class ;
rdfs:label "Caenorhabditis elegans" ;
rdfs:subClassOf obo:NCBITaxon_6231 .
obo:REO_0000001 a rdfs:Class ;
rdfs:label "reagent role"@en ;
rdfs:comment "a role inhering in a material entity intended to be applied in a scientific technique and participate in a chemical interaction that facilitates the generation of knowledge about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer." ;
rdfs:subClassOf obo:REO_0000248 .
obo:CL_0000060 a rdfs:Class ;
rdfs:label "odontoblast" ;
rdfs:comment "Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell." ;
rdfs:subClassOf obo:CL_0002159 .
obo:SO_1000149 a rdfs:Class ;
rdfs:label "bipartite_duplication" ;
rdfs:comment "An interchromosomal mutation whereby the (large) region between the first two breaks listed is lost, and the two flanking segments (one of them centric) are joined as a translocation to the free ends resulting from the third break." ;
rdfs:subClassOf obo:SO_1000038 .
obo:GO_0030182 a rdfs:Class ;
rdfs:label "neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuron." ;
rdfs:subClassOf obo:GO_0008150 .
obo:IAO_0000319 a rdfs:Class ;
rdfs:label "discussion section of a publication about an investigation"@en ;
rdfs:comment "A part of a publication about an investigation that is about the study interpretation of the investigation"@en ;
rdfs:subClassOf obo:IAO_0000314 .
obo:CHEBI_36928 a rdfs:Class ;
rdfs:label "carbon-13 atom" ;
rdfs:comment "A carbon atom that has formula C." ;
rdfs:subClassOf obo:CHEBI_27594 .
obo:REO_0000383 a rdfs:Class ;
rdfs:label "cancer cell in vivo" ;
rdfs:comment "a cell that is the output of some malignant cell transformation process whereby a cell in vivo becomes capable of causing cancer in an organism. Such cells are typically able to proliferate indefinitely if cultured in vitro." ;
rdfs:subClassOf obo:CL_0000003 , obo:OGMS_0000078 , obo:REO_0000149 , obo:REO_0000371 .
obo:CL_0002076 a rdfs:Class ;
rdfs:label "endo-epithelial cell" ;
rdfs:comment "An epithelial cell derived from endoderm." ;
rdfs:subClassOf obo:CL_0000066 .
obo:REO_0000571 a rdfs:Class ;
rdfs:label "obsolete_unmodified amino acid" ;
rdfs:subClassOf .
obo:REO_0000238 a rdfs:Class ;
rdfs:label "obsolete_significant incorporant" ;
rdfs:comment "an incorporant role inhering in an input material entity, that is (1) GAINED through an agent's intention for it be input into some material processing where it will contribute a significant amount of material to the composition of the specified output, and where this contributed material represents a significant part of the input material entity; and (2) REALIZED in the execution of such a material processing event." ;
rdfs:subClassOf .
obo:CHEBI_30415 a rdfs:Class ;
rdfs:label "astatine atom" ;
rdfs:comment "A halogen that has formula At." ;
rdfs:subClassOf obo:CHEBI_24473 .
obo:CHEBI_50319 a rdfs:Class ;
rdfs:label "nucleotide residue" ;
rdfs:subClassOf obo:REO_0000456 , obo:REO_0000943 .
obo:REO_0000264 a rdfs:Class ;
rdfs:label "obsolete_immortalized cell line cell" ;
rdfs:comment "a cultured multicellular organism cell that is part of an immortal cell culture having the capacity to proliferate indefinitely if given appropriate space and nutrients" ;
rdfs:subClassOf .
obo:UBERON_0007236 a rdfs:Class ;
rdfs:label "8 cell stage" ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:SO_0001504 a rdfs:Class ;
rdfs:label "assortment_derived_variation" ;
rdfs:comment "A chromosome variation derived from an event during meiosis." ;
rdfs:subClassOf obo:SO_0000240 .
obo:CL_0002029 a rdfs:Class ;
rdfs:label "Fc-epsilon RIalpha-low mast cell progenitor" ;
rdfs:comment "A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low." ;
rdfs:subClassOf obo:CL_0000831 .
obo:SO_0001784 a rdfs:Class ;
rdfs:label "complex_structural_alteration" ;
rdfs:comment "A structural sequence alteration where there are multiple equally plausible explanations for the change." ;
rdfs:subClassOf obo:SO_0001785 .
obo:CL_0000419 a rdfs:Class ;
rdfs:label "seam cell" ;
rdfs:comment "An epithelial fate stem cell found in flatworms." ;
rdfs:subClassOf obo:CL_0000036 .
obo:REO_0000349 a rdfs:Class ;
rdfs:label "synthesis objective" ;
rdfs:comment "a material combination objective to physically assemble more than one simpler input component into some larger product that bears some function, and wherein the autonomous identify of none of the specified inputs is retained (ie the specified output is distinct in identity from any of the specified inputs)" ;
rdfs:subClassOf obo:OBI_0000686 , obo:REO_0000688 .
obo:REO_0000841 a rdfs:Class ;
rdfs:label "obsolete_glucose" ;
rdfs:comment "monosaccharide sugar that is an important energy source in living organisms and is a component of many carbohydrates" ;
rdfs:subClassOf .
obo:GO_0005694 a rdfs:Class ;
rdfs:label "chromosome" ;
rdfs:comment "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." ;
rdfs:subClassOf obo:CARO_0000014 .
obo:REO_0000343 a rdfs:Class ;
rdfs:label "microarray RNA probe" ;
rdfs:comment "an RNA oligonucleotide that is immobilized on the surface of a microarray support substrate, to sequester and allow for the quantification of complementary target oligonucleotides from some nucleic acid sample under investigation" ;
rdfs:subClassOf obo:REO_0000274 , obo:REO_0000852 .
obo:REO_0000867 a rdf:Property ;
rdfs:label "transcribed_from" ;
rdfs:comment """shortcut relation for:
is_output_of (transcription and (realizes some ('information template role' and ('inheres in' some DNA))))""" ;
rdfs:domain obo:CHEBI_33697 ;
rdfs:range obo:CHEBI_33696 ;
rdfs:subPropertyOf obo:REO_0000833 .
obo:NCBITaxon_10016 a rdfs:Class ;
rdfs:label "Dipodomys" ;
rdfs:subClassOf obo:NCBITaxon_9989 .
obo:NCBITaxon_9544 a rdfs:Class ;
rdfs:label "Macaca mulatta" ;
rdfs:subClassOf obo:NCBITaxon_9539 .
obo:CHEBI_52457 a rdfs:Class ;
rdfs:label "selenium-77 atom" ;
rdfs:comment "The stable isotope of selenium with relative atomic mass 76.919915, 7.60 atom percent natural abundance and nuclear spin 1/2." ;
rdfs:subClassOf obo:CHEBI_27568 .
obo:CARO_0000032 a rdfs:Class ;
rdfs:label "organism subdivision" ;
rdfs:comment "Anatomical structure which is a primary subdivision of whole organism. The mereological sum of these is the whole organism." ;
rdfs:subClassOf obo:CARO_0000003 .
obo:NCBITaxon_131567 a rdfs:Class ;
rdfs:label "cellular organisms" ;
rdfs:subClassOf obo:OBI_0100026 .
obo:SO_1000161 a rdfs:Class ;
rdfs:label "unoriented_interchromosomal_transposition" ;
rdfs:comment "An interchromosomal transposition whereby a copy of the segment between the first two breaks listed is inserted at the third break; the orientation of the insertion with respect to its flanking segments is not recorded." ;
rdfs:subClassOf obo:SO_1000155 .
obo:CL_0000111 a rdfs:Class ;
rdfs:label "peripheral neuron" ;
rdfs:comment "A neuron that is part of nerve found outside the central nervous system." ;
rdfs:subClassOf obo:CL_0000029 .
obo:REO_0000146 a rdfs:Class ;
rdfs:label "cell subculturing"@en ;
rdfs:comment "a technique that takes a cell culture as input and removes some subset of cell culture cells (either through some non-selective splitting, or some cell selection process), and outputs one or more cell culture containers containing this subset of input cell culture cells." ;
rdfs:subClassOf obo:REO_0000135 .
obo:NCBITaxon_51754 a rdfs:Class ;
rdfs:label "Chamaeleo" ;
rdfs:subClassOf obo:NCBITaxon_8504 .
obo:REO_0000295 a rdfs:Class ;
rdfs:label "buffer" ;
rdfs:comment "A molecular reagent which is added to an acidic or basic solution in order to modify or maintain its pH value in a specified range" ;
rdfs:subClassOf obo:CHEBI_23367 , obo:REO_0000242 .
obo:REO_0000484 a rdfs:Class ;
rdfs:label "nucleic acid synthesis" ;
rdfs:comment "a molecular synthesis technique whereby a nucleic acid is constructed from simpler chemical entities, typically individual nucleotide monomers" ;
rdfs:subClassOf obo:OBI_0600040 .
obo:CL_0000874 a rdfs:Class ;
rdfs:label "splenic red pulp macrophage" ;
rdfs:comment "A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low." ;
rdfs:subClassOf obo:CL_0000871 .
obo:CL_0000503 a rdfs:Class ;
rdfs:label "theca cell" ;
rdfs:comment "A flattened stroma cell forming a sheath or theca outside the basal lamina lining the mature ovarian follicle. Thecal interstitial or stromal cells are steroidogenic, and produce primarily androgens which serve as precusors of estrogens in the granulosa cells." ;
rdfs:subClassOf obo:CL_0000499 .
obo:CL_0000533 a rdfs:Class ;
rdfs:label "primary motor neuron" ;
rdfs:subClassOf obo:CL_0000530 .
obo:REO_0000017 a rdfs:Class ;
rdfs:label "cDNA plasmid" ;
rdfs:comment "A plasmid with an insert derived from a cDNA molecule." ;
rdfs:subClassOf obo:REO_0000012 , obo:REO_0000975 .
obo:NCBITaxon_6997 a rdfs:Class ;
rdfs:label "Acheta domesticus" ;
rdfs:subClassOf obo:NCBITaxon_6993 .
obo:OBI_0000894 a rdfs:Class ;
rdfs:label "protein extract" ;
rdfs:comment "a protein extract is the output of an extraction process from tissues or cell cultures resulting in a solution of cellular and/or organellar proteins in buffer solution used to prevent degradation," ;
rdfs:subClassOf obo:OBI_0000423 .
obo:REO_0000884 a rdf:Property ;
rdfs:label "has_principal_part" ;
rdfs:comment "a non-transitive, irreflexive has_part relation between some material entity and a component or granular part that represents a specified element of high import, and wherein all other grains or components serve some secondary function in support of this principal part" ;
rdfs:range obo:PR_000000001 , obo:CHEBI_16516 , obo:CHEBI_33696 ;
rdfs:subPropertyOf .
obo:REO_0000892 a rdfs:Class ;
rdfs:label "biomolecular entity" ;
rdfs:comment "an organic molecular entity that is biologically-occurring (ie of a type produced or derived from an organism)" ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:CL_0000730 a rdfs:Class ;
rdfs:label "leading edge cell" ;
rdfs:comment "A cell at the front of a migrating epithelial sheet." ;
rdfs:subClassOf obo:CL_0000066 .
obo:CL_0000047 a rdfs:Class ;
rdfs:label "neuronal stem cell" ;
rdfs:comment "Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors." ;
rdfs:subClassOf obo:CL_0000048 .
obo:REO_0000835 a rdfs:Class ;
rdfs:label "recombinant protein production" ;
rdfs:subClassOf obo:REO_0000161 , obo:REO_0000834 .
obo:CHEBI_27560 a rdfs:Class ;
rdfs:label "boron atom" ;
rdfs:comment "A boron group element atom that has formula B." ;
rdfs:subClassOf obo:CHEBI_25585 .
obo:NCBITaxon_6762 a rdfs:Class ;
rdfs:label "Callinectes" ;
rdfs:subClassOf obo:NCBITaxon_6657 .
obo:CARO_0000021 a rdfs:Class ;
rdfs:label "simple organ" ;
rdfs:comment "Multi-tissue structure that is not part of a compound organ." ;
rdfs:subClassOf obo:CARO_0000055 .
obo:CL_0000091 a rdfs:Class ;
rdfs:label "Kupffer cell" ;
rdfs:comment "A tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system." ;
rdfs:subClassOf obo:CL_0000864 .
obo:CLO_0000032 a rdfs:Class ;
rdfs:label "mixed adherent and suspension cell line culturing" ;
rdfs:subClassOf obo:CLO_0000000 .
obo:CL_0000494 a rdfs:Class ;
rdfs:label "UV sensitive photoreceptor cell" ;
rdfs:comment "A photoreceptor cell that detects ultraviolet light." ;
rdfs:subClassOf obo:CL_0000210 .
obo:CL_0000933 a rdfs:Class ;
rdfs:label "type II NK T cell secreting interleukin-4" ;
rdfs:comment "A type II NK T cell that has been recently activated, secretes interleukin-4, and has the phenotype CD69-positive and downregulated NK markers." ;
rdfs:subClassOf obo:CL_0000922 .
obo:CHEBI_37974 a rdfs:Class ;
rdfs:label "silicon-29 atom" ;
rdfs:comment "The stable isotope of silicon with relative atomic mass 28.9764947, 4.683 atom percent natural abundancy, and nuclear spin (1)/2." ;
rdfs:subClassOf obo:CHEBI_27573 .
obo:CL_0002082 a rdfs:Class ;
rdfs:label "type II cell of adrenal medulla" ;
rdfs:comment "A chromaffin cell of the adrenal medulla that produces epinephrine." ;
rdfs:subClassOf obo:CL_0000336 .
obo:NCBITaxon_9615 a rdfs:Class ;
rdfs:label "Canis lupus familiaris" ;
rdfs:subClassOf obo:NCBITaxon_40674 .
obo:CL_0002343 a rdfs:Class ;
rdfs:label "decidual natural killer cell" ;
rdfs:comment "A natural killer cell subset that is found in the decidual of the uterus and is CD56-high, Galectin-1-positive and CD16-negative. This cell type represents the most abundant immune cell type in the decidual during the first trimester of pregnancy." ;
rdfs:subClassOf obo:CL_0000824 .
obo:IAO_0000013 a rdfs:Class ;
rdfs:label "journal article"@en ;
rdfs:comment "a report that is published in a journal"@en ;
rdfs:subClassOf obo:IAO_0000088 .
obo:SO_0001254 a rdfs:Class ;
rdfs:label "polyploid" ;
rdfs:comment "A kind of chromosome variation where the chromosome complement is an exact multiple of the haploid number and is greater than the diploid number." ;
rdfs:subClassOf obo:SO_1000182 .
obo:REO_0000274 a rdfs:Class ;
rdfs:label "unlabeled RNA probe" ;
rdfs:subClassOf obo:REO_0000041 .
obo:REO_0000776 a rdfs:Class ;
rdfs:label "lambda phage library" ;
rdfs:comment "An organism library containing trangenic lambda phage." ;
rdfs:subClassOf obo:REO_0000727 .
obo:CL_0002007 a rdfs:Class ;
rdfs:label "Kit-low, CD34-positive eosinophil progenitor cell" ;
rdfs:comment "A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell." ;
rdfs:subClassOf obo:CL_0000611 .
obo:CL_0000981 a rdfs:Class ;
rdfs:label "double negative memory B cell" ;
rdfs:comment "A memory B cell with the phenotype IgD-negative and CD27-negative." ;
rdfs:subClassOf obo:CL_0000787 .
obo:REO_0000923 a rdfs:Class ;
rdfs:label "short oligonucleotide DNA microarray" ;
rdfs:comment "a DNA microarray that is comprised of numerous collections of short DNA oligonucleotides (typically 25-30 nculeotides in length), which are spotted in a two-dimensional array onto a solid support matrix. The arrayed short oligo 'probes' are used to determine the identity or quantity of 'target' nucleic acid molecules (or nucleic acid-associated molecules) in some biological specimen of interest, based on quantification of hybridization between specimen nucleic acid targets and immobilized microarray oligos." ;
rdfs:subClassOf obo:OBI_0400148 .
a rdfs:Class ;
rdfs:label "occurrent" ;
rdfs:comment "Examples: the life of an organism, a surgical operation as processual context for a nosocomical infection, the spatiotemporal context occupied by a process of cellular meiosis, the most interesting part of Van Gogh's life, the spatiotemporal region occupied by the development of a cancer tumor" ;
rdfs:subClassOf .
obo:REO_0000242 a rdfs:Class ;
rdfs:label "molecular reagent" ;
rdfs:comment "a molecular entity that bears a reagent role in virtue of its being intended for application in a scientific technique to participate in a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material output." ;
rdfs:subClassOf obo:CHEBI_23367 , obo:REO_0000000 .
obo:IAO_0000302 a rdfs:Class ;
rdfs:label "author identification"@en ;
rdfs:comment "A textual entity intended to identify a particular author"@en ;
rdfs:subClassOf obo:IAO_0000300 .
obo:CL_0002335 a rdfs:Class ;
rdfs:label "brown preadipocyte" ;
rdfs:comment "A preadipocyte that is capable of differentiating into a brown adipocyte. This cell type expresses uncoupling protein-1, PPAR-gamma, PR-domain-containing 16; and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha)." ;
rdfs:subClassOf obo:CL_0002334 .
obo:REO_0000104 a rdfs:Class ;
rdfs:label "expression cell line"@en ;
rdfs:comment "a cell line that exhibits stable expression of an exogenous gene introduced in some DNA construct via some genetic transformation technique " ;
rdfs:subClassOf obo:CLO_0000019 , obo:REO_0000156 .
obo:IAO_0000183 a rdfs:Class ;
rdfs:label "dendrogram"@en ;
rdfs:subClassOf obo:IAO_0000038 .
obo:REO_0000376 a rdfs:Class ;
rdfs:label "material selection objective" ;
rdfs:comment "a material processing objective to separate a subset of some collection of material entities away from some total input collection, based on a specified attribute or set of attributes borne by the selected entities, and such that only the selected entities will be used for some subsequent planned process" ;
rdfs:subClassOf obo:OBI_0000681 .
obo:REO_0000361 a rdfs:Class ;
rdfs:label "obsolete_phosphorus-33 reagent" ;
rdfs:subClassOf .
obo:OBI_0500000 a rdfs:Class ;
rdfs:label "study design"@en ;
rdfs:comment "A study design is a plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution." ;
rdfs:subClassOf obo:IAO_0000104 .
obo:REO_0000401 a rdfs:Class ;
rdfs:label "selected passaged mortal cell culture" ;
rdfs:comment "a mortal cell culture that has been both passaged and output from some cell culture cell selection process whereby a specified subset of cells from an input cell culture is selected based on their exhibiting some desired feature, and propagated as a new cell culture." ;
rdfs:subClassOf obo:CLO_0000018 , obo:REO_0000399 , obo:REO_0000400 .
obo:REO_0000393 a rdfs:Class ;
rdfs:label "virus culture" ;
rdfs:subClassOf obo:REO_0000388 .
obo:CL_0000130 a rdfs:Class ;
rdfs:label "neuron associated cell (sensu Nematoda and Protostomia)" ;
rdfs:subClassOf obo:CL_0000095 .
obo:REO_0000855 a rdfs:Class ;
rdfs:label "data processing technique" ;
rdfs:comment "a technique which produces output data from input data" ;
rdfs:subClassOf obo:OBI_0200000 , obo:REO_0000075 .
obo:NCBITaxon_10442 a rdfs:Class ;
rdfs:label "Baculoviridae" ;
rdfs:subClassOf obo:NCBITaxon_10239 .
obo:CHEBI_17625 a rdfs:Class ;
rdfs:label "dUTP" ;
rdfs:comment "A pyrimidine 2'-deoxyribonucleoside 5'-triphosphate that has formula C9H15N2O14P3." ;
rdfs:subClassOf obo:CHEBI_16516 .
obo:REO_0000723 a rdfs:Class ;
rdfs:label "hydrocarbon reagent" ;
rdfs:comment "an organic small molecule reagent comprised only of carbon and hydrogen atoms. Hydrocarbons classify as lipids as they are soluble in non-polar solvents." ;
rdfs:subClassOf obo:REO_0000559 , obo:REO_0000720 .
obo:CL_0000929 a rdfs:Class ;
rdfs:label "CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma" ;
rdfs:comment "A mature NK T cell that secretes interferon-gamma and enhances Th1 immune responses." ;
rdfs:subClassOf obo:CL_0000924 .
obo:CL_0002444 a rdfs:Class ;
rdfs:label "Ly49H-positive natural killer cell" ;
rdfs:comment "A NK1.1-positive T cell that is Ly49H-positive." ;
rdfs:subClassOf obo:CL_0002438 .
obo:REO_0000758 a rdfs:Class ;
rdfs:label "genomic DNA construct" ;
rdfs:comment "a DNA construct that contains a construct insert that encodes only some natural genomic sequence from some organism." ;
rdfs:subClassOf obo:OBI_0000731 , obo:REO_0000007 .
obo:CL_0002018 a rdfs:Class ;
rdfs:label "CD71-negative, GlyA-positive orthochromatic erythroblast" ;
rdfs:comment "An erythroblast that is GlyA-positive and CD71-negative." ;
rdfs:subClassOf obo:CL_0000552 .
obo:CL_0002301 a rdfs:Class ;
rdfs:label "type B synovial cell" ;
rdfs:comment "A synovial cell type that resembles fibroblasts,has abundant granular endoplasmic reticulum but contains fewer vacuoles and vesicles. This cell type secretes glycoproteins and hyaluronic acid." ;
rdfs:subClassOf obo:CL_0000214 .
obo:REO_0000162 a rdfs:Class ;
rdfs:label "fibroblast-derived cell line"@en ;
rdfs:comment "an immortal cell line that is derived from a fibroblast cell type" ;
rdfs:subClassOf obo:CLO_0000019 .
obo:REO_0000168 a rdfs:Class ;
rdfs:label "inducible-expression cell line"@en ;
rdfs:comment "an immortal cell line that is capable of varied levels of expression of some exogenous genetic material in response to some environmetnal condition or chemical agent." ;
rdfs:subClassOf obo:CLO_0000019 , obo:REO_0000104 .
obo:REO_0000635 a rdfs:Class ;
rdfs:label "IgM monoclonal antibody reagent" ;
rdfs:subClassOf obo:REO_0000501 , obo:REO_0000614 .
obo:CHEBI_36080 a rdfs:Class ;
rdfs:label "protein" ;
rdfs:comment "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." ;
rdfs:subClassOf .
obo:PATO_0000169 a rdfs:Class ;
rdfs:label "viability" ;
rdfs:comment "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:UO_0000006 a rdfs:Class ;
rdfs:label "substance unit" ;
rdfs:comment "A unit which is a standardised quantity of an element or compound with uniform composition." ;
rdfs:subClassOf obo:REO_0000707 .
obo:SO_1000043 a rdfs:Class ;
rdfs:label "Robertsonian_fusion" ;
rdfs:comment "A non reciprocal translocation whereby the participating chromosomes break at their centromeres and the long arms fuse to form a single chromosome with a single centromere." ;
rdfs:subClassOf obo:SO_1000044 .
obo:CHEBI_37056 a rdfs:Class ;
rdfs:label "nucleoside tetraphosphate" ;
rdfs:subClassOf obo:CHEBI_25608 .
obo:CL_0000648 a rdfs:Class ;
rdfs:label "kidney granular cell" ;
rdfs:comment "A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation." ;
rdfs:subClassOf obo:CL_0000192 .
obo:CL_0000773 a rdfs:Class ;
rdfs:label "eosinophilic metamyelocyte" ;
rdfs:comment "A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative." ;
rdfs:subClassOf obo:CL_0002192 .
obo:CL_0000829 a rdfs:Class ;
rdfs:label "basophilic myeloblast" ;
rdfs:comment "A myeloblast committed to the basophil lineage." ;
rdfs:subClassOf obo:CL_0000835 .
obo:CHEBI_30217 a rdfs:Class ;
rdfs:label "helium atom" ;
rdfs:comment "A s-block element atom that has formula He." ;
rdfs:subClassOf obo:CHEBI_33309 .
obo:REO_0000417 a rdfs:Class ;
rdfs:label "molecular mass" ;
rdfs:subClassOf obo:PATO_0000125 , obo:PATO_0002182 .
obo:REO_0000931 a rdfs:Class ;
rdfs:label "obsolete_stable DNA transfection" ;
rdfs:subClassOf .
obo:REO_0000722 a rdfs:Class ;
rdfs:label "complex lipid reagent" ;
rdfs:comment "a lipid reagent comprised of carbon, hydrogen, oxygen, and at least one more type of atom (nitrogen, phosphorus, sulfur, etc) or containing some complex moiety such as a sugar or protein." ;
rdfs:subClassOf obo:REO_0000559 , obo:REO_0000721 .
obo:PATO_0001827 a rdfs:Class ;
rdfs:label "pseudohermaphrodite" ;
rdfs:comment "A biological sex quality inhering in an individual or a population by virtue of having internal reproductive organs of one sex and external sexual characteristics of the other sex." ;
rdfs:subClassOf obo:PATO_0001894 .
obo:REO_0000434 a rdfs:Class ;
rdfs:label "non-metal atomic reagent" ;
rdfs:comment "a non-metal atomic molecular entitu that bears a reagent role" ;
rdfs:subClassOf obo:REO_0000284 , obo:REO_0000789 .
obo:SO_0001746 a rdfs:Class ;
rdfs:label "paternal_uniparental_disomy" ;
rdfs:comment "Uniparental disomy is a sequence_alteration where a diploid individual receives two copies for all or part of a chromosome from the father and no copies of the same chromosome or region from the mother." ;
rdfs:subClassOf obo:SO_0001744 .
obo:CL_0002107 a rdfs:Class ;
rdfs:label "IgD-negative CD38-positive IgG memory B cell" ;
rdfs:comment "An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive." ;
rdfs:subClassOf obo:CL_0002105 .
obo:CL_0002191 a rdfs:Class ;
rdfs:label "granulocytopoietic cell" ;
rdfs:comment "A cell involved in the formation of a granulocyte." ;
rdfs:subClassOf obo:CL_0000839 .
obo:REO_0000191 a rdfs:Class ;
rdfs:label "obsolete_molecular label"@en ;
rdfs:comment "a molecular entity bearing a reagent role that is realized in a detection of label assay, where the molecular label associates directly or indirectly with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of label assay. A label may associate covalently or non-covalently with its target, and may or may not yield some detectable signal. In the latter case, the label is capable of binding to some moelcular entity bearing a reporter that is able to yield some detectable signal." ;
rdfs:subClassOf .
obo:CL_0002144 a rdfs:Class ;
rdfs:label "capillary endothelial cell" ;
rdfs:comment "An endothelial cell found in capillaries." ;
rdfs:subClassOf obo:CL_0000071 .
obo:REO_0000769 a rdfs:Class ;
rdfs:label "RNA interference oligonucleotide library" ;
rdfs:comment "A nucleic acid molecule library containing RNA oligonucleotides used to silence gene expression in cells through the RNAi pathway." ;
rdfs:subClassOf obo:REO_0000767 , obo:REO_0000768 .
obo:REO_0000947 a rdfs:Class ;
rdfs:label "genomic sequence region" ;
rdfs:comment "a genomic sequence feature with an extent fo one or more, that represents part of the genome of some cell or virion" ;
rdfs:subClassOf obo:REO_0000714 , obo:REO_0000988 .
obo:REO_0000822 a rdfs:Class ;
rdfs:label "molecular captor role" ;
rdfs:comment "a molecular probe role inhereing in a molecular entity used to capture specified target molecules from a complex mixture as part of some isolation technique" ;
rdfs:subClassOf obo:REO_0000510 .
obo:CHEBI_37982 a rdfs:Class ;
rdfs:label "sulfur-36 atom" ;
rdfs:comment "The stable isotope of sulfur with relative atomic mass 35.9670809. The least abundant (0.02 atom percent) isotope of naturally occurring sulfur." ;
rdfs:subClassOf obo:CHEBI_26833 .
obo:REO_0000219 a rdfs:Class ;
rdfs:label "experimental objective" ;
rdfs:subClassOf obo:IAO_0000005 .
obo:IAO_0000323 a rdfs:Class ;
rdfs:label "author contributions section"@en ;
rdfs:comment "A part of a publication that is about the specific contributions of each author"@en ;
rdfs:subClassOf obo:IAO_0000314 .
obo:IAO_0000422 a rdfs:Class ;
rdfs:label "postal address"@en ;
rdfs:comment "A textual entity that is used as directive to deliver something to a person, or organization" ;
rdfs:subClassOf obo:IAO_0000300 .
obo:REO_0000586 a rdfs:Class ;
rdfs:label "obsolete_T cell receptor complex" ;
rdfs:subClassOf .
obo:CL_0000842 a rdfs:Class ;
rdfs:label "mononuclear cell" ;
rdfs:comment "A leukocyte with a single non-segmented nucleus in the mature form." ;
rdfs:subClassOf obo:CL_0002087 .
obo:REO_0000950 a rdfs:Class ;
rdfs:label "material information macromolecule span" ;
rdfs:comment "a span of one or more linearly adjacent nucleotide residues (ie a continuous stretch or primary sequence) that comprise part of an information macromolecule" ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:CL_0000740 a rdfs:Class ;
rdfs:label "retinal ganglion cell" ;
rdfs:comment "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." ;
rdfs:subClassOf obo:CL_0000117 .
obo:REO_0000055 a rdfs:Class ;
rdfs:label "epithelial morphology"@en ;
rdfs:comment "Cells with epithelial morphology are polygonal in shape with more regular dimensions, and grow attached to a substrate in discrete patches." ;
rdfs:subClassOf obo:REO_0000138 .
obo:CL_0000879 a rdfs:Class ;
rdfs:label "meningeal macrophage" ;
rdfs:comment "A central nervous system macrophage found in the meninges (the three membranes that surround the brain). This macrophage types is highly phagocytic and expresses scavenger receptors." ;
rdfs:subClassOf obo:CL_0000878 .
obo:CL_0002184 a rdfs:Class ;
rdfs:label "basal proper cell of olfactory epithelium" ;
rdfs:comment "A flat or angular epithelial cell with condensed nuclei and darkly staining cytoplasm containing numerous intermediate filaments inserted into desmosomes contacting surrounding supporting cells; lie in contact with the basal lamina of olfactory epithelium." ;
rdfs:subClassOf obo:CL_0002169 .
obo:IAO_0000580 a rdfs:Class ;
rdfs:label "looking up a CRID"@en ;
rdfs:comment "A planned process in which a request to a CRID registry is made to return the information associated with a CRID symbol"@en ;
rdfs:subClassOf obo:OBI_0000011 .
obo:CL_0000789 a rdfs:Class ;
rdfs:label "alpha-beta T cell" ;
rdfs:comment "A T cell that expresses an alpha-beta T cell receptor complex." ;
rdfs:subClassOf obo:CL_0000084 .
obo:GO_0003823 a rdfs:Class ;
rdfs:label "antigen binding" ;
rdfs:comment "Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen." ;
rdfs:subClassOf obo:GO_0005488 .
obo:CL_0000071 a rdfs:Class ;
rdfs:label "blood vessel endothelial cell" ;
rdfs:comment "An endothelial cell that lines the vasculature." ;
rdfs:subClassOf obo:CL_0002139 .
obo:CL_0000957 a rdfs:Class ;
rdfs:label "large pre-B-II cell" ;
rdfs:comment "A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative." ;
rdfs:subClassOf obo:CL_0000955 .
obo:CHEBI_52451 a rdfs:Class ;
rdfs:label "boron-11" ;
rdfs:comment "The stable isotope of boron with relative atomic mass 11.009306, 80.1 atom percent natural abundance and nuclear spin 3/2." ;
rdfs:subClassOf obo:CHEBI_27560 .
obo:CL_0000710 a rdfs:Class ;
rdfs:label "neurecto-epithelial cell" ;
rdfs:comment "Epithelial cells derived from neural plate and neural crest." ;
rdfs:subClassOf obo:CL_0002077 .
obo:REO_0000322 a rdfs:Class ;
rdfs:label "obsolete_proxy role" ;
rdfs:comment "a role inhering in a material entity that is intended to be measured in some assay as a surrogate for some other material entity bearing an evaluant role realilzed in the assay" ;
rdfs:subClassOf .
obo:CHEBI_33493 a rdfs:Class ;
rdfs:label "radon-219 atom" ;
rdfs:comment "A radon atom that has formula Rn." ;
rdfs:subClassOf obo:CHEBI_33314 .
obo:REO_0000391 a rdfs:Class ;
rdfs:label "organism culture maintenance" ;
rdfs:subClassOf obo:REO_0000389 .
obo:CL_0000069 a rdfs:Class ;
rdfs:label "branched duct epithelial cell" ;
rdfs:subClassOf obo:CL_0000068 .
obo:NCBITaxon_675071 a rdfs:Class ;
rdfs:label "Virgaviridae" ;
rdfs:subClassOf obo:NCBITaxon_10239 .
obo:REO_0000172 a rdfs:Class ;
rdfs:label "obsolete_analyte label role"@en ;
rdfs:comment "a detector role that inheres in a molecular entity, and is realized in a material labeling technique in which it binds or is incorporated into an analyte of interest in some specimen that will serve as the evaluant in an anaytel assay" ;
rdfs:subClassOf .
obo:CL_0002120 a rdfs:Class ;
rdfs:label "CD24-positive CD38-negative IgG-negative class switched memory B cell" ;
rdfs:comment "An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative." ;
rdfs:subClassOf obo:CL_0002118 .
obo:SO_1000042 a rdfs:Class ;
rdfs:label "compound_chromosome" ;
rdfs:comment "A chromosome structure variant where a monocentric element is caused by the fusion of two chromosome arms." ;
rdfs:subClassOf obo:SO_1000183 .
obo:CL_0000122 a rdfs:Class ;
rdfs:label "stellate cell" ;
rdfs:subClassOf obo:CL_0000117 .
obo:REO_0000664 a rdfs:Class ;
rdfs:label "obsolete_contextual material separation technique" ;
rdfs:subClassOf .
obo:CL_0002447 a rdfs:Class ;
rdfs:label "CD94-negative natural killer cell" ;
rdfs:comment "A NK1.1-positive T cell that is CD94-negative." ;
rdfs:subClassOf obo:CL_0002438 .
obo:CL_0000853 a rdfs:Class ;
rdfs:label "olfactory epithelial support cell" ;
rdfs:comment "Olfactory epithelial support cell is a columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium. This cell type has a large, vertically, elongate, euchromatic nucleus, along with other nuclei, forms a layer superficial to the cell body of the receptor cell; sends long somewhat irregular microvilli into the mucus layer; at the base, with expanded end-feet containing numerous lamellated dense bodies resembling lipofuscin of neurons." ;
rdfs:subClassOf obo:CL_0002167 .
obo:CL_0002151 a rdfs:Class ;
rdfs:label "late promyelocyte" ;
rdfs:comment "A promyelocyte that is considerably smaller, with more condensed chromatin, and nucleoli are no longer conspicuous." ;
rdfs:subClassOf obo:CL_0000836 .
obo:CHEBI_46858 a rdfs:Class ;
rdfs:label "L-tyrosine residue" ;
rdfs:subClassOf obo:CHEBI_33700 .
obo:NCBITaxon_6693 a rdfs:Class ;
rdfs:label "lobster" ;
rdfs:subClassOf obo:NCBITaxon_6657 .
obo:SO_0001506 a rdfs:Class ;
rdfs:label "variant_genome" ;
rdfs:comment "A collection of sequences (often chromosomes) of an individual." ;
rdfs:subClassOf obo:SO_0001026 .
obo:so_genome_of a rdf:Property ;
rdfs:label "genome_of" ;
rdfs:domain obo:SO_0001026 ;
rdfs:range obo:OBI_0100026 .
obo:CL_0000609 a rdfs:Class ;
rdfs:label "vestibular hair cell" ;
rdfs:comment "A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem." ;
rdfs:subClassOf obo:CL_0002374 .
obo:REO_0000860 a rdfs:Class ;
rdfs:label "group" ;
rdfs:subClassOf obo:OBI_0000245 .
obo:CL_0000385 a rdfs:Class ;
rdfs:label "prohemocyte (sensu Nematoda and Protostomia)" ;
rdfs:subClassOf obo:CL_0000390 .
obo:CL_0000558 a rdfs:Class ;
rdfs:label "reticulocyte" ;
rdfs:comment "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." ;
rdfs:subClassOf obo:CL_0000764 .
obo:REO_0000653 a rdfs:Class ;
rdfs:label "target of material removal role" ;
rdfs:comment "a target of modification role that inheres in an entity from which material is removed in a material component separation process. This component separation process is 'asymmetric', in that the separated material exhibits a differential composition from the target from which it was removed (ie one or more specified parts of the target become discriminately and differentially segregated between the outputs of this separation process)" ;
rdfs:subClassOf obo:REO_0000828 .
obo:REO_0000830 a rdfs:Class ;
rdfs:label "structural rearrangement objective" ;
rdfs:comment "a material processing objective to structural rearrange the existing components of some material entity, such that no new material becomes physically associated, and no material is removed (ie no net gain or loss of matter)." ;
rdfs:subClassOf obo:OBI_0000456 .
obo:REO_0000458 a rdfs:Class ;
rdfs:label "nucleoside triphosphate reagent" ;
rdfs:comment "a nucleobasic reagent that is a nucleoside containing three phosphate groups bound to its sugar ring" ;
rdfs:subClassOf obo:CHEBI_17326 , obo:REO_0000805 , obo:REO_0000978 .
obo:REO_0000888 a rdfs:Class ;
rdfs:label "obsolete_experimental antibody target 0" ;
rdfs:comment """This class allows us to talk about the material entity which an antibody is used to target in an experiment, even in cases where the actual antigen is not known (e.g. antibodies known to recognize a certain cell or organelle type, for example, but where the actual molecular antigen associated with these targets is not known).
As the part_of relation is reflexive, it is acceptible for antigens themselves to be experimental antibody targets (ie they are still part_of some experimental antigen, in that they are part_of themselves)""" ;
rdfs:subClassOf .
obo:CL_0002032 a rdfs:Class ;
rdfs:label "hematopoietic oligopotent progenitor cell" ;
rdfs:comment "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers." ;
rdfs:subClassOf obo:CL_0000988 .
obo:OBI_0001151 a rdfs:Class ;
rdfs:label "genetically modified material"@en ;
rdfs:comment "a material entity, organism or cell, that is the output of a genetic transformation process. "@en ;
rdfs:subClassOf obo:OBI_0000047 , .
obo:CL_0002170 a rdfs:Class ;
rdfs:label "keratinized cell of the oral mucosa" ;
rdfs:comment "A keratinized cell located in the hard palate or gingiva." ;
rdfs:subClassOf obo:CL_0002336 .
obo:REO_0000961 a rdfs:Class ;
rdfs:label "gene mutation objective" ;
rdfs:comment "a genetic modification objective to introduce a sequence alteration into a specified gene of interest, typically in order to alter the activity of the target gene" ;
rdfs:subClassOf obo:OBI_0001153 .
obo:REO_0000034 a rdfs:Class ;
rdfs:label "RNA reagent" ;
rdfs:comment "a ribonucleic acid or a ribonucleic acid analog that bears a reagent role" ;
rdfs:subClassOf obo:CHEBI_33697 , obo:REO_0000003 .
obo:CL_0000968 a rdfs:Class ;
rdfs:label "Be cell" ;
rdfs:comment "A mature B cell that produces cytokines that can influence CD4 T cell differentiation." ;
rdfs:subClassOf obo:CL_0000785 .
obo:CL_0000762 a rdfs:Class ;
rdfs:label "nucleated thrombocyte" ;
rdfs:comment "A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates." ;
rdfs:subClassOf obo:CL_0000763 .
obo:REO_0000102 a rdfs:Class ;
rdfs:label "molecular binding disposition"@en ;
rdfs:comment "a disposition inhering in a molecular entity to form selective, non-covalent, often stoichiometric, interactions with one or more specific sites on another molecule." ;
rdfs:subClassOf .
obo:CL_0000977 a rdfs:Class ;
rdfs:label "IgG short lived plasma cell" ;
rdfs:comment "A short lived plasma cell that secretes IgG." ;
rdfs:subClassOf obo:CL_0000975 .
obo:CL_0000576 a rdfs:Class ;
rdfs:label "monocyte" ;
rdfs:comment "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells." ;
rdfs:subClassOf obo:CL_0002087 .
obo:CL_0000950 a rdfs:Class ;
rdfs:label "IgE plasmablast" ;
rdfs:comment "A plasmablast that secretes IgE." ;
rdfs:subClassOf obo:CL_0000980 .
obo:OBI_0001204 a rdfs:Class ;
rdfs:label "SNP microarray"@en ;
rdfs:comment "a DNA microarray used to detect polymorphisms in DNA samples" ;
rdfs:subClassOf obo:OBI_0400148 .
obo:PATO_0000117 a rdfs:Class ;
rdfs:label "size" ;
rdfs:comment "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:CL_0000104 a rdfs:Class ;
rdfs:label "multipolar neuron" ;
rdfs:comment "Neuron with an axon and two or more dendrites." ;
rdfs:subClassOf obo:CL_0000540 .
obo:DOID_12858 a rdfs:Class ;
rdfs:label "Huntington's disease" ;
rdfs:comment "A neurodegenerative disease that has_material_basis_in expansion of CAG repeats resulting in neuron degeneration affecting muscle coordination, cognitive abilities." ;
rdfs:subClassOf obo:DOID_1289 .
obo:CL_0002162 a rdfs:Class ;
rdfs:label "internal epithelial cell of tympanic membrane" ;
rdfs:comment "An extremely flattened cell type found on the inner side of the tympanic membrane. The surface of this cell type carries sparse pleomorphic microvilli that are more common near the junctional zones." ;
rdfs:subClassOf obo:CL_0002076 .
obo:CL_0001024 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-negative hematopoietic stem cell" ;
rdfs:comment "CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive." ;
rdfs:subClassOf obo:CL_0000037 .
obo:DOID_305 a rdfs:Class ;
rdfs:label "carcinoma" ;
rdfs:comment "A cell type cancer that has_material_basis_in abnormally proliferating cells derived_from epithelial cells." ;
rdfs:subClassOf obo:DOID_0050687 .
obo:REO_0000440 a rdfs:Class ;
rdfs:label "bioactive molecular entity" ;
rdfs:comment "a molecular entity thatbears a disposition to interact with, be processed by, or affect the function or activity of one or more biological molecules in the context of a cell, tissue, or organism" ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:REO_0000253 a rdfs:Class ;
rdfs:label "research material specification" ;
rdfs:comment "an action specification indicating an agent's intent to use a material entity as a research material in some technique as part of an investigation" ;
rdfs:subClassOf obo:IAO_0000007 .
obo:CHEBI_25362 a rdfs:Class ;
rdfs:label "elemental molecule" ;
rdfs:comment "A molecule all atoms of which have the same atomic number." ;
rdfs:subClassOf obo:CHEBI_33259 .
obo:REO_0000790 a rdfs:Class ;
rdfs:label "metalloid atomic molecular entity" ;
rdfs:subClassOf obo:CHEBI_33238 , obo:REO_0000432 .
obo:REO_0000151 a rdfs:Class ;
rdfs:label "transgenic cell line"@en ;
rdfs:comment "a cell line which or derives from some transgenic organism or has itself been modified through some transgenic technique, such that it contains exogenous genetic material from a different cell or organism than that from which it was derived. This exogenous genetic material is capable of being stably replicated and inherited through subsequent generations of the transgenic cell line." ;
rdfs:subClassOf obo:CLO_0000019 , obo:REO_0000156 , obo:REO_0000157 .
obo:CL_0000584 a rdfs:Class ;
rdfs:label "enterocyte" ;
rdfs:comment "An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen." ;
rdfs:subClassOf obo:CL_0000239 .
obo:CL_0000446 a rdfs:Class ;
rdfs:label "chief cell of parathyroid gland" ;
rdfs:comment "An epithelial cell of the parathyroid gland that is arranged in wide, irregular interconnecting columns; responsible for the synthesis and secretion of parathyroid hormone." ;
rdfs:subClassOf obo:CL_0002260 .
obo:REO_0000231 a rdfs:Class ;
rdfs:label "chemical reaction" ;
rdfs:comment "a process in which chemical entities under go some transformation, transport or binding event whereby chemical bonds between atoms are rearranged." .
obo:CL_0001032 a rdfs:Class ;
rdfs:label "cortical granule cell" ;
rdfs:comment "Granule cell that is part of the cerebral cortex." ;
rdfs:subClassOf obo:CL_0000120 .
obo:REO_0000877 a rdfs:Class ;
rdfs:label "linear epitope" ;
rdfs:subClassOf obo:CHEBI_24433 , obo:OBI_1110001 .
obo:REO_0000637 a rdf:Property ;
rdfs:label "is_recognized_by" ;
rdfs:range .
obo:REO_0000285 a rdfs:Class ;
rdfs:label "covalent reporter" ;
rdfs:comment "a molecular reporter that is not capable of autonomous non-covalent association with a molecular target, such that it must be covalenly attached to an analyte of interest, or to a targeted molecular label that can direct it to an analyte" ;
rdfs:subClassOf obo:REO_0000323 , obo:REO_0000972 .
a rdfs:Class ;
rdfs:label "function" ;
rdfs:comment "Definition: A realizable entity [snap:RealizableEntity] the manifestation of which is an essentially end-directed activity of a continuant [snap:Continuant] entity in virtue of that continuant [snap:Continuant] entity being a specific kind of entity in the kind or kinds of contexts that it is made for." ;
rdfs:subClassOf .
obo:CL_0002133 a rdfs:Class ;
rdfs:label "stromal cell of ovorain cortex" ;
rdfs:comment "A stromal cell of the ovarian cortex." ;
rdfs:subClassOf obo:CL_0002132 .
a rdfs:Class ;
rdfs:label "role" ;
rdfs:comment "Definition: A realizable entity [snap:RealizableEntity] the manifestation of which brings about some result or end that is not essential to a continuant [snap:Continuant] in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant [snap:Continuant] in some kinds of natural, social or institutional contexts." ;
rdfs:subClassOf .
obo:NCBITaxon_8293 a rdfs:Class ;
rdfs:label "Caudata" ;
rdfs:subClassOf obo:NCBITaxon_8292 .
obo:REO_0000811 a rdfs:Class ;
rdfs:label "GTP reagent" ;
rdfs:subClassOf obo:CHEBI_15996 , obo:REO_0000457 .
obo:NCBITaxon_8782 a rdfs:Class ;
rdfs:label "Aves" ;
rdfs:subClassOf obo:NCBITaxon_7742 .
obo:OGMS_0000082 a rdfs:Class ;
rdfs:label "pathological invasion" ;
rdfs:comment "TODO: Define."@en ;
rdfs:subClassOf obo:OGMS_0000061 .
obo:OBI_0200168 a rdfs:Class ;
rdfs:label "correction objective"@en ;
rdfs:comment "A correction objective is a data transformation objective where the aim is to correct for error, noise or other impairments to the input of the data transformation or derived from the data transformation itself"@en ;
rdfs:subClassOf obo:OBI_0200166 .
obo:REO_0000446 a rdfs:Class ;
rdfs:label "organic small molecule reagent" ;
rdfs:comment "an organic molecular reagent of low molecular weight, which is by definition not a polymer, and can interact with and affect the function or activity of one or more biological molecules in the context of a cell, tissue, or organism." ;
rdfs:subClassOf obo:REO_0000186 , obo:REO_0000445 .
obo:SO_1000037 a rdfs:Class ;
rdfs:label "chromosomal_duplication" ;
rdfs:comment "An extra chromosome." ;
rdfs:subClassOf obo:SO_1000183 .
obo:REO_0000953 a rdfs:Class ;
rdfs:label "cDNA sequence region" ;
rdfs:comment "a DNA sequence that represents exon sequences of a gene, joined in the order they appear in the full gene sequence. This sequence is typically represented in a cDNA molecule, which is synthesized by reverse transcriptase using RNA as a template, and reflects the seqeunce of some mRNA transcribable from the gene. Thus, cDNA sequence is constrained to represent the complement of some mRNA sequence that can be transcribed from a particular gene." ;
rdfs:subClassOf obo:SO_0000831 .
obo:CL_0000827 a rdfs:Class ;
rdfs:label "pro-T cell" ;
rdfs:comment "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." ;
rdfs:subClassOf obo:CL_0000838 .
obo:CL_0002173 a rdfs:Class ;
rdfs:label "extraglomerular mesangial cell" ;
rdfs:comment "A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells." ;
rdfs:subClassOf obo:CL_0002320 .
obo:OBI_0666667 a rdfs:Class ;
rdfs:label "nucleic acid extraction"@en ;
rdfs:comment "a material separation to recover the nucleic acid fraction of an input material"@en ;
rdfs:subClassOf obo:OBI_0302884 .
obo:BFO_0000055 a rdf:Property ;
rdfs:label "realizes"@en ;
rdfs:comment "Relation between a process and a function, where the unfolding of the process requires the execution of the function. Class level: P realizes F iff: given any p that instantiates P, there exists some f, t such that f instantiates F at t and p *realizes* f. Here, *realizes* is the primitive instance level relation" ;
rdfs:range .
obo:NCBITaxon_1305 a rdfs:Class ;
rdfs:label "Streptococcus sanguinis" ;
rdfs:subClassOf obo:NCBITaxon_1300 .
obo:REO_0000350 a rdfs:Class ;
rdfs:label "obsolete_protein microarray" ;
rdfs:comment "a molecular microarray that is used to measure protein abundance in a specimen of interest, which consists of fixed substrate (typically glass or silicon) onto which different molecules of protein (typically antibodies) have been affixed at separate locations in an ordered manner thus forming a microscopic array. Alternatively, an array of non-protein molecules, such as DNA promoter sequences, can be fixed to the array as capture probes for a protein mixture that is incubated with the array. " ;
rdfs:subClassOf .
obo:UBERON_0007232 a rdfs:Class ;
rdfs:label "2 cell stage" ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:REO_0000006 a rdfs:Class ;
rdfs:label "reagent library" ;
rdfs:comment "a reagent that is a collection of reagents of the same type. Each member of this collection is either a single reagent (e.g. an organism or cell line), or, more typically, each member of the collection is itself a collection of a single type of molecule (e.g. a collection of identical molecules, or genetically identical bacteria)." ;
rdfs:subClassOf obo:REO_0000000 , .
obo:CL_0000778 a rdfs:Class ;
rdfs:label "mononuclear osteoclast" ;
rdfs:comment "A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts." ;
rdfs:subClassOf obo:CL_0000092 .
obo:NCBITaxon_8090 a rdfs:Class ;
rdfs:label "Oryzias latipes" ;
rdfs:subClassOf obo:NCBITaxon_32443 .
obo:CL_0000898 a rdfs:Class ;
rdfs:label "naive T cell" ;
rdfs:comment "Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." ;
rdfs:subClassOf obo:CL_0002419 .
obo:REO_0000683 a rdfs:Class ;
rdfs:label "synthetic" ;
rdfs:subClassOf obo:REO_0000682 .
obo:REO_0000311 a rdfs:Class ;
rdfs:label "obsolete_non-molecular reagent role 2" ;
rdfs:comment """a role inhering in a processed non-molecular entity (includes objects, aggregates, and mixtures, collections) that has as parts (winston component_parts or stuff_parts?) only molecular entities intended to be immediately consumed in a chemical reaction as part of some scientific technique, where it facilitates the generation of data about some other entity, or facilitates the production of some material entity that does not derive from the bearer of the reagent role.
'Immediate consumption' requires that the bearer's molecular parts are 'significantly altered' during the execution of a single experiment, such that any re-use would require some processing to restore them to a usable state (e.g. washing of bound probes and contaminants from a microarray plate, washing and re-culturing of a cell line)""" ;
rdfs:subClassOf obo:REO_0000309 .
obo:OBI_0000047 a rdfs:Class ;
rdfs:label "processed material"@en ;
rdfs:comment "Is a material entity that is created or changed during material processing."@en ;
rdfs:subClassOf .
obo:REO_0000575 a rdfs:Class ;
rdfs:label "experimental modification" ;
rdfs:comment "a material processing technique whereby physical alterations (ie structural or compositional changes) are made to a specified input material, to produce some output that represents a modified version of the specified input material." ;
rdfs:subClassOf obo:REO_0000159 .
obo:CL_0000918 a rdfs:Class ;
rdfs:label "Tc2 cell" ;
rdfs:comment "A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4." ;
rdfs:subClassOf obo:CL_0000908 .
obo:REO_0000260 a rdfs:Class ;
rdfs:label "fluorescent molecular reporter" ;
rdfs:comment "a molecular label that is capable of producing a fluorescent detectable signal" ;
rdfs:subClassOf obo:REO_0000323 .
obo:CL_0002059 a rdfs:Class ;
rdfs:label "CD8alpha-positive thymic conventional dendritic cell" ;
rdfs:comment "A conventional thymic dendritic cell that is CD8alpha-positive." ;
rdfs:subClassOf obo:CL_0000941 .
obo:CL_0000690 a rdfs:Class ;
rdfs:label "R2 photoreceptor cell" ;
rdfs:subClassOf obo:CL_0000488 .
obo:REO_0000072 a rdfs:Class ;
rdfs:label "spindle-like morphology"@en ;
rdfs:subClassOf obo:REO_0000138 .
obo:CL_0000595 a rdfs:Class ;
rdfs:label "enucleate erythrocyte" ;
rdfs:comment "An erythrocyte lacking a nucleus." ;
rdfs:subClassOf obo:CL_0000232 .
obo:CHEBI_52661 a rdfs:Class ;
rdfs:label "Alexa Fluor 488" ;
rdfs:comment "A fluorescent dye of absorption wavelength 495 nm and emission wavelength 519 nm, derived from a 3,6-diaminoxanthenium-4,5-disulfate." ;
rdfs:subClassOf obo:REO_0000258 .
obo:CL_0002353 a rdfs:Class ;
rdfs:label "fetal liver hematopoietic progenitor cell" ;
rdfs:comment "A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative." ;
rdfs:subClassOf obo:CL_0002352 .
obo:SO_1000151 a rdfs:Class ;
rdfs:label "bipartite_inversion" ;
rdfs:comment "A chromosomal inversion caused by three breaks in the same chromosome; both central segments are inverted in place (i.e., they are not transposed)." ;
rdfs:subClassOf obo:SO_1000030 .
obo:MOD_01240 a rdfs:Class ;
rdfs:label "ubiquitination signature tetrapeptidyl lysine" ;
rdfs:comment "A protein modification that crosslinks the N6-amino of a peptidyl lysine with the carboxyl of leucyl-arginyl-glycyl-glycine, the C-terminal tetrapeptide of ubiquitin." ;
rdfs:subClassOf obo:MOD_00033 .
obo:REO_0000423 a rdfs:Class ;
rdfs:label "metalloid elemental molecule" ;
rdfs:comment "a molecule comprised only of a single type of metalloid atom" ;
rdfs:subClassOf obo:CHEBI_25362 .
obo:REO_0000964 a rdfs:Class ;
rdfs:label "DNA construct engineering" ;
rdfs:comment "a material processing technique with the objective to engineer and produce a DNA construct capable of carrying nucleic acids sequences for delivery to and propagation in cells" ;
rdfs:subClassOf obo:REO_0000159 .
obo:REO_0000629 a rdfs:Class ;
rdfs:label "IgA monoclonal antibody reagent" ;
rdfs:subClassOf obo:REO_0000501 , obo:REO_0000611 .
obo:IAO_0000403 a rdfs:Class ;
rdfs:label "three dimensional cartesian spatial coordinate datum"@en ;
rdfs:comment "A cartesion spatial coordinate datum that uses three values to specify a position within a three dimensional spatial region"@en ;
rdfs:subClassOf obo:IAO_0000400 .
obo:CL_0000816 a rdfs:Class ;
rdfs:label "immature B cell" ;
rdfs:comment "An immature B cell is a precursor B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation." ;
rdfs:subClassOf obo:CL_0000817 .
obo:PATO_0001018 a rdfs:Class ;
rdfs:label "physical quality" ;
rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:CL_0000379 a rdfs:Class ;
rdfs:label "sensory processing neuron" ;
rdfs:subClassOf obo:CL_0000540 .
obo:MOD_00048 a rdfs:Class ;
rdfs:label "O4'-phospho-L-tyrosine" ;
rdfs:comment "A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine." ;
rdfs:subClassOf obo:MOD_00696 .
obo:CL_0000468 a rdfs:Class ;
rdfs:label "neuroglioblast" ;
rdfs:subClassOf obo:CL_0000047 .
obo:CL_0000003 a rdfs:Class ;
rdfs:label "native cell" ;
rdfs:comment "A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment)." ;
rdfs:subClassOf obo:CARO_0000003 , obo:CL_0000000 .
obo:OBI_0000835 a rdfs:Class ;
rdfs:label "manufacturer" ;
rdfs:comment "A person or organization that has a manufacturer role" ;
rdfs:subClassOf obo:REO_0000230 , .
obo:CHEBI_16311 a rdfs:Class ;
rdfs:label "dCTP" ;
rdfs:comment "A 2'-deoxycytidine phosphate having cytosine as the nucleobase." ;
rdfs:subClassOf obo:CHEBI_16516 .
obo:CL_0000349 a rdfs:Class ;
rdfs:label "extraembryonic cell" ;
rdfs:subClassOf obo:CL_0002371 .
obo:REO_0000598 a rdfs:Class ;
rdfs:label "obsolete_disposition to be bound by an adaptive immune receptor" ;
rdfs:subClassOf .
obo:REO_0000672 a rdfs:Class ;
rdfs:label "obsolete_material attachment objective" ;
rdfs:subClassOf obo:REO_0000667 .
obo:CL_0000880 a rdfs:Class ;
rdfs:label "choroid-plexus macrophage" ;
rdfs:comment "A central nervous system macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This cell expresses scavenger receptors." ;
rdfs:subClassOf obo:CL_0000878 .
obo:REO_0000406 a rdfs:Class ;
rdfs:label "unpassaged unicellular organism culture" ;
rdfs:comment "a unicellular organism culture that has not been passaged" ;
rdfs:subClassOf obo:REO_0000125 , obo:REO_0000480 .
obo:REO_0000220 a rdfs:Class ;
rdfs:label "obsolete_goat serum albumin" ;
rdfs:subClassOf .
obo:UBERON_0000110 a rdfs:Class ;
rdfs:label "neurula stage" ;
rdfs:comment "Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:PATO_0001396 a rdfs:Class ;
rdfs:label "cellular quality" ;
rdfs:comment "A monadic quality of continuant that exists at the cellular level of organisation." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:CL_0000637 a rdfs:Class ;
rdfs:label "chromophil cell of anterior pituitary gland" ;
rdfs:comment "A cell that stains readily in the anterior pituitary gland." ;
rdfs:subClassOf obo:CL_0000166 .
obo:REO_0000023 a rdfs:Class ;
rdfs:label "viral shuttle plasmid" ;
rdfs:comment "A recombinant plasmid into which a gene of interest can be inserted, and which contains flanking sequence elements that allow for packaging of this genetic cargo into viral capsids. Viral shuttle plasmids may contain additional genes required for capsid protein production and assembly, or may require helper plasmids which produce these proteins. Cloning the gene of interest into a shuttle vector allows transferring the gene into the viral genome by means of homologous recombination in an viral packaging cell line." ;
rdfs:subClassOf obo:REO_0000975 .
obo:CL_0002361 a rdfs:Class ;
rdfs:label "primitive erythroid progenitor" ;
rdfs:comment "A progenitor cell that is capable of forming colonies of primitive erythrocytes in the blood island of the yolk sac. First arrive at E7.5 in mouse and expresses CD41." ;
rdfs:subClassOf obo:CL_0002417 .
obo:REO_0000083 a rdfs:Class ;
rdfs:label "obsolete_gene trapping " ;
rdfs:comment "A technique that is used to introduce insertional mutations across the mammalian genome using a gene trap vector. " ;
rdfs:subClassOf .
obo:CL_0000751 a rdfs:Class ;
rdfs:label "rod bipolar cell" ;
rdfs:comment "A bipolar neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer." ;
rdfs:subClassOf obo:CL_0000749 .
obo:NCBITaxon_9539 a rdfs:Class ;
rdfs:label "Macaca" ;
rdfs:subClassOf obo:NCBITaxon_9443 .
obo:CL_0002072 a rdfs:Class ;
rdfs:label "nodal myocyte" ;
rdfs:comment "A specialized cardiac myocyte in the sinuatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery." ;
rdfs:subClassOf obo:CL_0002086 .
obo:CL_0000626 a rdfs:Class ;
rdfs:label "olfactory granule cell" ;
rdfs:comment "Granule cell that is part of the olfactory bulb." ;
rdfs:subClassOf obo:CL_0000120 .
obo:IAO_0000132 a rdfs:Class ;
rdfs:label "lot number"@en ;
rdfs:comment "A lot number is an information content entity which is an identical sequence of character borne by part of manufactured product or its packaging for each instances of a product class in a discrete batch of an item. Lot numbers are usually assigned to each separate production run of an item. Manufacturing as a lot might be due to a variety of reasons, for example, a single process during which many individuals are made from the same portion of source material. Lot numbers can be encoded in a pattern of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
rdfs:subClassOf obo:IAO_0000028 .
obo:NCBITaxon_7994 a rdfs:Class ;
rdfs:label "Astyanax mexicanus" ;
rdfs:subClassOf obo:NCBITaxon_32443 .
obo:CL_0000143 a rdfs:Class ;
rdfs:label "guidepost cell" ;
rdfs:subClassOf obo:CL_0000130 .
obo:CL_0002122 a rdfs:Class ;
rdfs:label "B220-positive CD38-positive IgG-negative class switched memory B cell" ;
rdfs:comment "A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative." ;
rdfs:subClassOf obo:CL_0002119 .
obo:REO_0000899 a rdfs:Class ;
rdfs:label "nucleic acid antibody target" ;
rdfs:subClassOf obo:CHEBI_33696 , obo:REO_0000893 .
obo:CHEBI_60003 a rdfs:Class ;
rdfs:label "pure substance" ;
rdfs:comment "A pure substance is a chemical substance composed of multiple molecules, which are all of the same kind." ;
rdfs:subClassOf obo:CHEBI_59999 .
obo:REO_0000754 a rdfs:Class ;
rdfs:label "miRNA cDNA construct library" ;
rdfs:comment "A cDNA construct library that carries small cDNA inserts from a pool of size-selected cDNAs, representing putative endogenous miRNAs." ;
rdfs:subClassOf obo:REO_0000753 .
obo:REO_0000103 a rdfs:Class ;
rdfs:label "hybridizing disposition"@en ;
rdfs:comment "a disposition, inhering in a single-stranded nucleic acid or nucleic acid analog, to form a non-covalent, sequence-specific interaction with other single-stranded nucleic acids or analogs exhibitiing a complementary sequence " ;
rdfs:subClassOf obo:REO_0000102 .
obo:CL_0000566 a rdfs:Class ;
rdfs:label "angioblastic mesenchymal cell" ;
rdfs:comment "A mesenchymal stem cell capable of developing into blood vessel endothelium." ;
rdfs:subClassOf obo:CL_0000048 .
obo:CL_0002180 a rdfs:Class ;
rdfs:label "mucous cell of stomach" ;
rdfs:comment "A mucous cell in the epithelium of the stomach." ;
rdfs:subClassOf obo:CL_0002178 .
obo:SO_0000549 a rdfs:Class ;
rdfs:label "inversion_derived_duplication_plus_aneuploid" ;
rdfs:comment "A chromosome generated by recombination between two inversions; has a duplication at one end and presumed to have a deficiency or duplication at the other end of the inversion." ;
rdfs:subClassOf obo:SO_1000038 .
obo:CL_0000924 a rdfs:Class ;
rdfs:label "CD4-negative, CD8-negative type I NK T cell" ;
rdfs:comment "A type I NK T cell that has the phenotype CD4-negative and CD8-negative." ;
rdfs:subClassOf obo:CL_0000921 .
obo:REO_0000597 a rdfs:Class ;
rdfs:label "experimental antibody target" ;
rdfs:comment "a material which represents an intended target of some antibody reagent in some scientific technique" ;
rdfs:subClassOf obo:REO_0000644 , .
obo:IAO_0000017 a rdfs:Class ;
rdfs:label "model number"@en ;
rdfs:comment "A model number is an information content entity specifically borne by catalogs, design specifications, advertising materials, inventory systems and similar that is about manufactured objects of the same class. The model number is an alternative term for the class. The manufactered objects may or may not also bear the model number. Model numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
rdfs:subClassOf obo:IAO_0000028 .
obo:CHEBI_24061 a rdfs:Class ;
rdfs:label "fluorine atom" ;
rdfs:comment "A halogen that has formula F." ;
rdfs:subClassOf obo:CHEBI_24473 .
obo:OBI_0302884 a rdfs:Class ;
rdfs:label "extraction"@en ;
rdfs:comment "A material separation in which a desired component of an input material is separated from the remainder" ;
rdfs:subClassOf obo:OBI_0600014 , obo:REO_0000159 .
obo:REO_0000908 a rdfs:Class ;
rdfs:label "bio-organic small molecule" ;
rdfs:subClassOf obo:REO_0000445 , obo:REO_0000892 , obo:REO_0000977 .
obo:REO_0000013 a rdfs:Class ;
rdfs:label "RNA interference plasmid" ;
rdfs:comment "A recombinant plasmid expressing transcripts that are processed into small RNA molecules which target genes for post-transcriptional silencing through the RNAi pathway." ;
rdfs:subClassOf obo:REO_0000012 , obo:REO_0000096 , obo:REO_0000097 , obo:REO_0000975 .
obo:CL_0000082 a rdfs:Class ;
rdfs:label "epithelial cell of lung" ;
rdfs:subClassOf obo:CL_0000066 .
obo:CL_0002003 a rdfs:Class ;
rdfs:label "CD34-positive, GlyA-negative erythroid progenitor cell" ;
rdfs:comment "An erythroid progenitor cell that is CD34-positive and is GlyA-negative." ;
rdfs:subClassOf obo:CL_0000038 .
obo:REO_0000576 a rdfs:Class ;
rdfs:label "non-canonical amino acid" ;
rdfs:comment "any amino acid that is not in the set of 22 canonical amino acids that are naturally incorporated into proteins during translation" ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:CL_0000845 a rdfs:Class ;
rdfs:label "marginal zone B cell" ;
rdfs:comment "A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD23-negative, CD21/35-high." ;
rdfs:subClassOf obo:CL_0000785 .
obo:CL_0000469 a rdfs:Class ;
rdfs:label "ganglion mother cell" ;
rdfs:subClassOf obo:CL_0000468 .
obo:CL_0000913 a rdfs:Class ;
rdfs:label "effector memory CD8-positive, alpha-beta T cell" ;
rdfs:comment "A CD8-positive, alpha beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative." ;
rdfs:subClassOf obo:CL_0000909 .
obo:CL_0002043 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-negative multipotent progenitor cell" ;
rdfs:comment "A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative." ;
rdfs:subClassOf obo:CL_0000837 .
obo:IAO_0000001 a rdfs:Class ;
rdfs:label "conditional specification"@en ;
rdfs:comment "a directive information entity that specifies what should happen if the trigger condition is fulfilled"@en ;
rdfs:subClassOf obo:IAO_0000033 .
obo:NCBITaxon_562 a rdfs:Class ;
rdfs:label "Escherichia coli" ;
rdfs:subClassOf obo:NCBITaxon_2 .
obo:REO_0000445 a rdfs:Class ;
rdfs:label "organic small molecule" ;
rdfs:comment "An organic small molecule is an organic molecule of low molecular weight, which is by definition not a polymer, and can interact with and affect the function or activity of one or more biological molecules in the context of a cell, tissue, or organism." ;
rdfs:subClassOf obo:CHEBI_50860 , obo:REO_0000440 .
obo:CHEBI_16633 a rdfs:Class ;
rdfs:label "L-selenocysteine" ;
rdfs:comment "A selenocysteine that has formula C3H7NO2Se." ;
rdfs:subClassOf obo:REO_0000545 .
obo:REO_0000397 a rdfs:Class ;
rdfs:label "clonal cell line" ;
rdfs:comment "an immortal cell line that derives from a single multicellular organism cell that is isolated from some population of cells, propagated, and immortalized to create a new immortal cell line" ;
rdfs:subClassOf obo:CLO_0000019 , obo:REO_0000648 .
obo:CL_0002000 a rdfs:Class ;
rdfs:label "Kit-positive erythroid progenitor cell" ;
rdfs:comment "An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative." ;
rdfs:subClassOf obo:CL_0000038 .
obo:PR_000002968 a rdfs:Class ;
rdfs:label "post-translationally modified amino-acid residue" ;
rdfs:comment "A modified amino-acid residue that was modified after its incorporation into an amino acid chain." ;
rdfs:subClassOf .
obo:UO_0000003 a rdfs:Class ;
rdfs:label "time unit" ;
rdfs:comment "A unit which is a standard measure of the dimension in which events occur in sequence." ;
rdfs:subClassOf obo:REO_0000707 .
obo:CHEBI_17677 a rdfs:Class ;
rdfs:label "CTP" ;
rdfs:comment "A pyrimidine ribonucleoside 5'-triphosphate that has formula C9H16N3O14P3." ;
rdfs:subClassOf obo:CHEBI_17972 .
obo:DOID_14566 a rdfs:Class ;
rdfs:label "disease of cellular proliferation" ;
rdfs:comment "A disease that is characterized by abnormally rapid cell division." ;
rdfs:subClassOf obo:DOID_4 .
obo:REO_0000608 a rdfs:Class ;
rdfs:label "IgG2c immunoglobulin complex, circulating" ;
rdfs:subClassOf obo:GO_0042571 .
obo:REO_0000618 a rdfs:Class ;
rdfs:label "IgG1 monoclonal antibody reagent" ;
rdfs:subClassOf obo:REO_0000501 , obo:REO_0000605 .
obo:REO_0000048 a rdfs:Class ;
rdfs:label "pathological cell"@en ;
rdfs:comment "a cell in vivo that has undergone a pathological transformation that contributes to or results from the disease course processes of some disease" ;
rdfs:subClassOf obo:OGMS_0000078 , obo:REO_0000520 .
obo:NCBITaxon_6608 a rdfs:Class ;
rdfs:label "Sepiidae" ;
rdfs:subClassOf obo:NCBITaxon_6605 .
obo:REO_0000248 a rdfs:Class ;
rdfs:label "ascribed role" ;
rdfs:comment "a role assigned unilaterally by an intentional agent to an entity that plays no active part in its bearing of the role (ie it is not earned or chosen by the bearer). This role is conferred through some planning process which specifies some intended use by the agent, and is realized through the bearer's participation in a process achieving this intended use." ;
rdfs:subClassOf obo:REO_0000699 .
obo:CL_0000843 a rdfs:Class ;
rdfs:label "follicular B cell" ;
rdfs:comment "A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative." ;
rdfs:subClassOf obo:CL_0000822 .
obo:CHEBI_18019 a rdfs:Class ;
rdfs:label "L-lysine" ;
rdfs:comment "An L-alpha-amino acid; the L-isomer of lysine." ;
rdfs:subClassOf obo:REO_0000545 .
obo:CL_0002086 a rdfs:Class ;
rdfs:label "specialized cardiac myocyte" ;
rdfs:comment "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart." ;
rdfs:subClassOf obo:CL_0000746 .
obo:REO_0000367 a rdfs:Class ;
rdfs:label "clonal unicellular organism culture" ;
rdfs:comment "a unicellular organism culture that derives from a single unicellular organism that is isolated from some population of cells and propagated to create a new culture" ;
rdfs:subClassOf obo:REO_0000125 , obo:REO_0000648 .
obo:NCBITaxon_10508 a rdfs:Class ;
rdfs:label "Adenoviridae" ;
rdfs:subClassOf obo:NCBITaxon_10239 .
obo:CL_0000922 a rdfs:Class ;
rdfs:label "type II NK T cell" ;
rdfs:comment "An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d." ;
rdfs:subClassOf obo:CL_0000814 .
obo:CL_0002305 a rdfs:Class ;
rdfs:label "epithelial cell of distal tubule" ;
rdfs:comment "An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH." ;
rdfs:subClassOf obo:CL_0002078 .
obo:CL_0000908 a rdfs:Class ;
rdfs:label "CD8-positive, alpha-beta cytokine secreting effector T cell" ;
rdfs:comment "A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines." ;
rdfs:subClassOf obo:CL_0000912 .
obo:CHEBI_24859 a rdfs:Class ;
rdfs:label "iodine atom" ;
rdfs:comment "Chemical element with atomic number 53." ;
rdfs:subClassOf obo:CHEBI_24473 .
obo:OBI_0000576 a rdfs:Class ;
rdfs:label "scattered molecular aggregate"@en ;
rdfs:comment "A scattered molecular aggregate is a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates"@en ;
rdfs:subClassOf obo:REO_0000863 .
obo:REO_0000470 a rdfs:Class ;
rdfs:label "obsolete_non-information biomacromolecule" ;
rdfs:subClassOf obo:REO_0000465 .
obo:CL_0002208 a rdfs:Class ;
rdfs:label "brush cell of bronchus" ;
rdfs:comment "A brush cell found in the epithelium of bronchus." ;
rdfs:subClassOf obo:CL_0002328 .
obo:CHEBI_33818 a rdfs:Class ;
rdfs:label "oxygen-16 atom" ;
rdfs:comment "The stable isotope of oxygen with relative atomic mass 15.994914. The most abundant (99.76 atom percent) isotope of naturally occurring oxygen." ;
rdfs:subClassOf obo:CHEBI_25805 .
obo:REO_0000765 a rdfs:Class ;
rdfs:label "phagemid genomic library" ;
rdfs:comment " A genomic library that contains discrete collections of phagemid constructs carrying DNA inserts from a source organism, such that the collection of DNA inserts represents the entire genome of the source organism. " ;
rdfs:subClassOf obo:REO_0000757 .
obo:REO_0000061 a rdfs:Class ;
rdfs:label "stem cell-like morphology"@en ;
rdfs:subClassOf obo:REO_0000138 .
obo:CL_0000958 a rdfs:Class ;
rdfs:label "T1 B cell" ;
rdfs:comment "A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative." ;
rdfs:subClassOf obo:CL_0000818 .
obo:REO_0000871 a rdfs:Class ;
rdfs:label "biomaterial" ;
rdfs:comment "a material entity or organismal origin, ie is part of, derives from, or is produced by an organism, or is part of, derives from, or is produced by some material that derives from an organism (such as a cell line)" ;
rdfs:subClassOf .
obo:CL_0002195 a rdfs:Class ;
rdfs:label "hepatic stem cell" ;
rdfs:comment "A stem cell that can give rise to the cells of the liver." ;
rdfs:subClassOf obo:CL_0000048 .
obo:CHEBI_51760 a rdfs:Class ;
rdfs:label "Alexa Fluor 546" ;
rdfs:comment "An organic heteropentacyclic compound that has formula C44H46Cl3N4NaO14S3." ;
rdfs:subClassOf obo:REO_0000258 .
obo:CL_0002364 a rdfs:Class ;
rdfs:label "cortical thymic epithelial cell" ;
rdfs:comment "An epithelial cell of the cortical portion of the thymus. Epithelial cells in this region are required for positive selection of CD8-positive T cells." ;
rdfs:subClassOf obo:CL_0002293 .
obo:CL_0000555 a rdfs:Class ;
rdfs:label "neuronal brush cell" ;
rdfs:subClassOf obo:CL_0000117 .
obo:CL_0000659 a rdfs:Class ;
rdfs:label "eggshell secreting cell" ;
rdfs:comment "An extracellular matrix secreting cell that secretes eggshell." ;
rdfs:subClassOf obo:CL_0000500 .
obo:REO_0000903 a rdfs:Class ;
rdfs:label "cell component antibody target" ;
rdfs:subClassOf obo:CARO_0000014 , obo:REO_0000872 .
obo:CL_0000745 a rdfs:Class ;
rdfs:label "horizontal cell" ;
rdfs:comment "A neuron that laterally connects other neurons in the inner nuclear layer of the retina." ;
rdfs:subClassOf obo:CL_0000099 .
obo:UBERON_0000104 a rdfs:Class ;
rdfs:label "life cycle" ;
rdfs:comment "An entire span of an organism's life, commencing with the zygote stage and ending in the death of the organism." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:CL_0000107 a rdfs:Class ;
rdfs:label "autonomic neuron" ;
rdfs:comment "A neruon whose cell body is within an autonomic ganglion." ;
rdfs:subClassOf obo:CL_0000029 .
obo:CL_0000065 a rdfs:Class ;
rdfs:label "ependymal cell" ;
rdfs:comment "A neurectoderm derived cell that lines the neural lumen." ;
rdfs:subClassOf obo:CL_0000710 .
obo:IAO_0000320 a rdfs:Class ;
rdfs:label "references section"@en ;
rdfs:comment "A part of a document that has citations as parts"@en ;
rdfs:subClassOf obo:IAO_0000314 .
obo:REO_0000828 a rdfs:Class ;
rdfs:label "target of physical modification role" ;
rdfs:comment "a role realized by a planned process in which the bearer is physically modified by some agent, through the addition or removal of material, or the alteration of its internal structure" ;
rdfs:subClassOf obo:REO_0000248 .
obo:GO_0001171 a rdfs:Class ;
rdfs:label "reverse transcription" ;
rdfs:comment "A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis." ;
rdfs:subClassOf obo:GO_0008150 .
obo:NCBITaxon_5890 a rdfs:Class ;
rdfs:label "Tetrahymena" ;
rdfs:subClassOf obo:NCBITaxon_5878 .
obo:CL_0002429 a rdfs:Class ;
rdfs:label "CD69-positive double-positive thymocyte" ;
rdfs:comment "A double-positive thymocyte that is CD69-positive and has begun positive selection." ;
rdfs:subClassOf obo:CL_0000809 .
obo:CL_0002167 a rdfs:Class ;
rdfs:label "olfactory epithelial cell" ;
rdfs:comment "A specialized cell involved in sensory perception of smell." ;
rdfs:subClassOf obo:CL_0000710 .
obo:NCBITaxon_59729 a rdfs:Class ;
rdfs:label "Taeniopygia guttata" ;
rdfs:subClassOf obo:NCBITaxon_8782 .
obo:GO_0017145 a rdfs:Class ;
rdfs:label "stem cell division" ;
rdfs:comment "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." ;
rdfs:subClassOf obo:GO_0008150 .
obo:REO_0000469 a rdfs:Class ;
rdfs:label "monoclonal antibody production" ;
rdfs:subClassOf obo:REO_0000463 , obo:REO_0000834 .
obo:GO_0019815 a rdfs:Class ;
rdfs:label "B cell receptor complex" ;
rdfs:comment "An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." ;
rdfs:subClassOf obo:GO_0019814 .
obo:CHEBI_51231 a rdfs:Class ;
rdfs:label "DAPI" ;
rdfs:comment "An indole that has formula C16H15N5." ;
rdfs:subClassOf obo:REO_0000288 , obo:REO_0000445 , obo:REO_0000976 .
obo:SO_1000015 a rdfs:Class ;
rdfs:label "A_to_G_transition" ;
rdfs:comment "A transition of an adenine to a guanine." ;
rdfs:subClassOf obo:SO_1000014 .
obo:CL_0000420 a rdfs:Class ;
rdfs:label "syncytial epithelial cell" ;
rdfs:subClassOf obo:CL_0000066 .
obo:CL_0002443 a rdfs:Class ;
rdfs:label "Ly49CI-positive natural killer cell" ;
rdfs:comment "A NK1.1-positive T cell that is Ly49Cl-positive." ;
rdfs:subClassOf obo:CL_0002438 .
obo:OBI_0200157 a rdfs:Class ;
rdfs:label "data vector reduction objective"@en ;
rdfs:comment "Data vector reduction is a data transformation objective in which k m-dimensional input vectors are reduced to j m-dimensional output vectors, where j is smaller than k."@en ;
rdfs:subClassOf obo:OBI_0200166 .
obo:CL_0000166 a rdfs:Class ;
rdfs:label "chromaffin cell" ;
rdfs:comment "A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system." ;
rdfs:subClassOf obo:CL_0000710 .
obo:REO_0000184 a rdfs:Class ;
rdfs:label "obsolete_chemical reagent role"@en ;
rdfs:comment "a reagent role played by a non-protein or nucleic acid molecular entity, and realized during an investigation through its participation in a chemical reaction that detects, measures, modifies, or produces other molecular entities." ;
rdfs:subClassOf .
obo:CL_0002292 a rdfs:Class ;
rdfs:label "type I cell of carotid body" ;
rdfs:comment "A round or oval neuroepithelial cell that contacts other type I cells or capillaries. They occur in clusters that are surrounded by sheath cells (type-II cells) in the carotid body. This cell type is capable of secreting a number of neurotransmitters." ;
rdfs:subClassOf obo:CL_0000710 .
obo:OBI_0600036 a rdfs:Class ;
rdfs:label "establishing cell culture"@en ;
rdfs:comment "establishing a cell culture is a process which results in creating an in vitro environment in which cells are sustained from input material containing cells. input: cell-containing material, output cell culture, part of cell culturing. Cells are originally plated at a certain concentration referred to as seeding density."@en ;
rdfs:subClassOf obo:REO_0000135 , obo:REO_0000159 , obo:REO_0000366 , obo:REO_0000989 .
obo:OBI_0000678 a rdfs:Class ;
rdfs:label "portioning objective" ;
rdfs:comment "is the objective to separate material into multiple portions, each of which contains a similar composition of the input material." ;
rdfs:subClassOf obo:OBI_0000639 .
obo:MOD_00033 a rdfs:Class ;
rdfs:label "crosslinked residues" ;
rdfs:comment "A protein modification that crosslinks two or more amino acid residues with covalent bonds." ;
rdfs:subClassOf obo:PR_000025513 .
obo:MOD_00723 a rdfs:Class ;
rdfs:label "N-acetylated L-lysine" ;
rdfs:comment "A protein modification that effectively converts an L-lysine residue to either N2-acetyl-L-lysine, or N6-acetyl-L-lysine." ;
rdfs:subClassOf obo:MOD_00394 .
obo:NCBITaxon_8314 a rdfs:Class ;
rdfs:label "Salamandridae" ;
rdfs:subClassOf obo:NCBITaxon_8293 .
obo:CL_0000338 a rdfs:Class ;
rdfs:label "neuroblast (sensu Nematoda and Protostomia)" ;
rdfs:subClassOf obo:CL_0000031 .
obo:NCBITaxon_1336 a rdfs:Class ;
rdfs:label "Streptococcus equi" ;
rdfs:subClassOf obo:NCBITaxon_1300 .
obo:REO_0000626 a rdfs:Class ;
rdfs:label "IgG3 polyclonal antibody reagent" ;
rdfs:subClassOf .
obo:CL_0002126 a rdfs:Class ;
rdfs:label "CD25-positive, CD27-positive immature gamma-delta T cell" ;
rdfs:comment "A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low)." ;
rdfs:subClassOf obo:CL_0002405 .
obo:REO_0000982 a rdfs:Class ;
rdfs:label "APotentiallyUsefulObsoleteClass" ;
rdfs:subClassOf .
obo:CL_0002212 a rdfs:Class ;
rdfs:label "type II muscle cell" ;
rdfs:comment "A fast muscle fiber cell that stores energy in the form of glycogen and creatine phosphate." ;
rdfs:subClassOf obo:CL_0000190 .
obo:CL_0000453 a rdfs:Class ;
rdfs:label "Langerhans cell" ;
rdfs:comment "Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus." ;
rdfs:subClassOf obo:CL_0000990 .
obo:REO_0000194 a rdfs:Class ;
rdfs:label "obsolete_molecular probe"@en ;
rdfs:comment """a molecular label capable of targeted, non-covalent binding to some moelcular entity of interest, to facilitate the target's association with a reporter and allow its detection.
Molecular probes contain some structural element that targets them to associate non-covalently with an analyte (or with a label associated with an analyte). As probes themselves do no produce a signal, they must recruit some molecular reporter in order to be detected.""" ;
rdfs:subClassOf obo:REO_0000191 .
obo:CL_0002354 a rdfs:Class ;
rdfs:label "yolk sac hematopoietic stem cell" ;
rdfs:comment "A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive." ;
rdfs:subClassOf obo:CL_0002352 .
obo:CHEBI_36935 a rdfs:Class ;
rdfs:label "nitrogen-13 atom" ;
rdfs:comment "The radioactive isotope of nitrogen with relative atomic mass 13.0057386. The longest-lived nitrogen radionuclide with half-life of 9.965 min." ;
rdfs:subClassOf obo:CHEBI_25555 .
obo:REO_0000130 a rdfs:Class ;
rdfs:label "cell culture transformation"@en ;
rdfs:comment "a process by which cultured cells are manipulated to undergo genetic modifications, such that they display properties of cancer, including the ability to grow in the absence of survival factors and the ability to divide without being specifically instructed to do so from outside the cell." ;
rdfs:subClassOf obo:REO_0000135 , obo:REO_0000366 , obo:REO_0000974 .
obo:REO_0000409 a rdfs:Class ;
rdfs:label "obsolete_information biomacromolecule" ;
rdfs:comment """This class represents natural or artificial polymers that carry sequence information of a genetic nature (ie, information that is translatale to a nucleic acid sequence in a defined way - such that it can be aligned with or related to or translated into a sequence of nucleic acids). In this sense, in encompasses a broader set of instances than ChEBI 'information biomacromolecule', which could be imported as a subclass of ReO:information macromolecule.
So, for ex, a morpholino is a synthetic oligo that is not made of nucleic acids, but it carries sequence information that relates each monomer to some specific nucleic acid or set of nucleic acids, allowing it to bind a nucleic acid an a sequence specific manner.
Other examples of 'genetic sequence macromolecules' are other nucleic acid analogs such as locked nucleic acids or peptide nucleic acids, and synthetic primers or peptides, etc.""" ;
rdfs:subClassOf obo:REO_0000465 .
obo:CL_0000500 a rdfs:Class ;
rdfs:label "follicular epithelial cell" ;
rdfs:subClassOf obo:CL_0000066 .
obo:REO_0000542 a rdfs:Class ;
rdfs:label "polar solvent" ;
rdfs:subClassOf obo:REO_0000541 .
obo:CL_0000464 a rdfs:Class ;
rdfs:label "epidermoblast" ;
rdfs:comment "An epidermal progenitor cell that arises from neuroectoderm and in turn gives rise to the epidermal sheath of ventral and cephalic regions." ;
rdfs:subClassOf obo:CL_0000710 .
obo:REO_0000569 a rdfs:Class ;
rdfs:label "obsolete_non-polar solvent reagent" ;
rdfs:comment "a non-polar solvent that bears a reagent role" ;
rdfs:subClassOf .
obo:REO_0000882 a rdfs:Class ;
rdfs:label "preservative reagent role" ;
rdfs:comment "a reagent role inhering in a material entity that serves to preserve the integrity, stability, conformation, or activity of some other material with which it interacts" ;
rdfs:subClassOf obo:REO_0000001 .
obo:REO_0000919 a rdfs:Class ;
rdfs:label "nucleobase reagent" ;
rdfs:comment "a nucleobase molecule that has a reagent role" ;
rdfs:subClassOf obo:CHEBI_18282 , obo:REO_0000805 , obo:REO_0000978 .
obo:SO_1000155 a rdfs:Class ;
rdfs:label "interchromosomal_transposition" ;
rdfs:comment "A chromosome structure variation whereby a transposition occurred between chromosomes." ;
rdfs:subClassOf obo:SO_1000031 .
obo:CL_0002424 a rdfs:Class ;
rdfs:label "DN2b thymocyte" ;
rdfs:comment "A DN2 thymocyte that is Kit-low." ;
rdfs:subClassOf obo:CL_0000806 .
obo:NCBITaxon_30259 a rdfs:Class ;
rdfs:label "Psocoptera" ;
rdfs:subClassOf obo:NCBITaxon_50557 .
obo:CHEBI_36930 a rdfs:Class ;
rdfs:label "carbon-10 atom" ;
rdfs:comment "A carbon atom that has formula C." ;
rdfs:subClassOf obo:CHEBI_27594 .
obo:CARO_0000028 a rdfs:Class ;
rdfs:label "female organism" ;
rdfs:comment "Gonochoristic organism that can produce female gametes." ;
rdfs:subClassOf obo:CARO_0000048 .
obo:CL_0002285 a rdfs:Class ;
rdfs:label "type III taste bud cell" ;
rdfs:comment "A taste receptor cell that is characterized by morphologically identifiable synaptic contacts with the gustatory nerve fibers and expression of the synaptic membrane protein-25 (SNAP-25) and NCAM." ;
rdfs:subClassOf obo:CL_0000209 .
obo:MOD_01148 a rdfs:Class ;
rdfs:label "ubiquitinylated lysine" ;
rdfs:comment "A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin." ;
rdfs:subClassOf obo:PR_000025513 .
obo:CL_0000014 a rdfs:Class ;
rdfs:label "germ line stem cell" ;
rdfs:subClassOf obo:CL_0000034 .
obo:CL_0001028 a rdfs:Class ;
rdfs:label "CD7-positive lymphoid progenitor cell" ;
rdfs:comment "CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative." ;
rdfs:subClassOf obo:CL_0000051 .
obo:REO_0000523 a rdfs:Class ;
rdfs:label "obsolete_experimentally modified cell in vitro" ;
rdfs:comment "a cell in vitro that is output from a cell modification technique that introduces physical changes to the cell" ;
rdfs:subClassOf .
obo:NCBITaxon_8830 a rdfs:Class ;
rdfs:label "Anatidae" ;
rdfs:subClassOf obo:NCBITaxon_8782 .
obo:CL_0000097 a rdfs:Class ;
rdfs:label "mast cell" ;
rdfs:comment "A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development." ;
rdfs:subClassOf obo:CL_0000766 .
obo:REO_0000129 a rdfs:Class ;
rdfs:label "selective cell subculturing"@en ;
rdfs:comment "A material processing technique whereby a specified subset of cells from an input cell culture is selected based on their exhibiting some desired feature, and propagated into a new cell culture. Selection can be based on physical cell separation, drug selection, environmental selection, or other approaches." ;
rdfs:subClassOf obo:REO_0000146 .
obo:REO_0000834 a rdfs:Class ;
rdfs:label "bioengineered protein production" ;
rdfs:comment "a material processing technique whereby some protein synthesis biological process is intentionally and manipulated by an agent in such a way as to determine or impact the sequence of the specified protein output from this process. The sequence of the desired output protein is in some way designed or engineered by an intentional agent. " ;
rdfs:subClassOf obo:REO_0000159 .
obo:CL_0000823 a rdfs:Class ;
rdfs:label "immature natural killer cell" ;
rdfs:comment "A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR)." ;
rdfs:subClassOf obo:CL_0000623 .
obo:REO_0000560 a rdfs:Class ;
rdfs:label "obsolete_lipid small molecule reagent" ;
rdfs:comment "a lipid reagent that does not contain a long hydrocarbon chain comprised primarily of a repeating carbon backbone saturted with bonds to hydrogen, or unsaturated and containing C=C double bonds." ;
rdfs:subClassOf .
obo:REO_0000852 a rdfs:Class ;
rdfs:label "microarray oligonucleotide probe" ;
rdfs:comment "an oligonucleotide that is immobilized on the surface of a microarray support substrate, to sequester and allow for the quantification of complementary target oligonucleotides from some nucleic acid sample under investigation" ;
rdfs:subClassOf obo:REO_0000281 , obo:REO_0000821 .
obo:CHEBI_63299 a rdfs:Class ;
rdfs:label "carbohydrate derivative" ;
rdfs:comment "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:CL_0000199 a rdfs:Class ;
rdfs:label "mechanoreceptor cell" ;
rdfs:comment "A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system." ;
rdfs:subClassOf obo:CL_0000006 .
obo:REO_0000901 a rdfs:Class ;
rdfs:label "polypeptide antibody target" ;
rdfs:subClassOf obo:REO_0000892 , obo:REO_0000893 .
obo:NCBITaxon_12637 a rdfs:Class ;
rdfs:label "Dengue virus" ;
rdfs:subClassOf obo:NCBITaxon_11051 .
obo:NCBITaxon_10633 a rdfs:Class ;
rdfs:label "Simian virus 40" ;
rdfs:subClassOf obo:NCBITaxon_10624 .
obo:REO_0000676 a rdfs:Class ;
rdfs:label "test class 3" ;
rdfs:subClassOf .
obo:SO_1000140 a rdfs:Class ;
rdfs:label "hetero_compound_chromosome" ;
rdfs:comment "A compound chromosome whereby two arms from different chromosomes are connected through the centromere of one of them." ;
rdfs:subClassOf obo:SO_1000042 .
obo:REO_0000066 a rdfs:Class ;
rdfs:label "large multinucleate morphology"@en ;
rdfs:subClassOf obo:REO_0000138 .
obo:NCBITaxon_263 a rdfs:Class ;
rdfs:label "Francisella tularensis" ;
rdfs:subClassOf obo:NCBITaxon_2 .
obo:CL_0000966 a rdfs:Class ;
rdfs:label "Bm4 B cell" ;
rdfs:comment "A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor." ;
rdfs:subClassOf obo:CL_0000844 .
obo:REO_0000026 a rdfs:Class ;
rdfs:label "baculoviral shuttle plasmid" ;
rdfs:comment "A viral plasmid carrying sequence elements that allow for packaging of genetic cargo into baculoviral capsids for expression in target cells. Baculoviral expression systems are used for transient and stable protein expression in insect cells (and related invertebrates such as arachnids and crustaceans). " ;
rdfs:subClassOf obo:REO_0000023 .
obo:MOD_00215 a rdfs:Class ;
rdfs:label "heparan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine" ;
rdfs:comment "A protein modification that effectively cross-links an L-serine residue to the polymer heparan sulfate by a D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl tetrasaccharide." ;
rdfs:subClassOf obo:MOD_00693 .
obo:CL_0002357 a rdfs:Class ;
rdfs:label "fetal derived definitive erythrocyte" ;
rdfs:comment "A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins." ;
rdfs:subClassOf obo:CL_0000595 .
obo:CL_0000118 a rdfs:Class ;
rdfs:label "basket cell" ;
rdfs:subClassOf obo:CL_0000117 .
obo:REO_0000531 a rdfs:Class ;
rdfs:label "unmodified multicellular organism cell" ;
rdfs:comment "a multicellular organism cell that has not been experimentally modified through some cell modification technique, and thus exhibits a physical structure and internal biochemical metabolism that are the result of natural processes" ;
rdfs:subClassOf obo:REO_0000371 .
obo:CL_0002436 a rdfs:Class ;
rdfs:label "mature CD4 single-positive thymocyte" ;
rdfs:comment "A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor." ;
rdfs:subClassOf obo:CL_0000624 .
obo:SO_1000009 a rdfs:Class ;
rdfs:label "transition" ;
rdfs:comment "Change of a pyrimidine nucleotide, C or T, into an other pyrimidine nucleotide, or change of a purine nucleotide, A or G, into an other purine nucleotide." ;
rdfs:subClassOf obo:SO_0001483 .
obo:IAO_0000303 a rdfs:Class ;
rdfs:label "institutional identification"@en ;
rdfs:comment "A textual entity intended to identify a particular institution"@en ;
rdfs:subClassOf obo:IAO_0000300 .
obo:CL_0002022 a rdfs:Class ;
rdfs:label "Ly-76 high positive erythrocyte" ;
rdfs:comment "An enucleate erythrocyte that is Lyg-76-high." ;
rdfs:subClassOf obo:CL_0000595 .
obo:CL_0001025 a rdfs:Class ;
rdfs:label "Kit-positive, Sca1-positive common lymphoid progenitor" ;
rdfs:comment "A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low." ;
rdfs:subClassOf obo:CL_0000051 .
obo:MOD_01187 a rdfs:Class ;
rdfs:label "L-pyrrolysine residue" ;
rdfs:comment "A protein modification that inserts or replaces a residue with an L-pyrrolysine residue, a natural pretranslational modification." ;
rdfs:subClassOf obo:PR_000025513 .
obo:REO_0000971 a rdfs:Class ;
rdfs:label "establishing selected cell culture" ;
rdfs:comment "an establishing cell culture process whereby a culture is established from some selected population of cells. In this process, some initial, uniform populaiton of like cells of a certain type are isolated from a biological specimen, and then a selection process is applied on this population input cells to isolate only some subpopulation exhibitiing specified attributes (e.g. T-cells expression of certain cell surface marker)." ;
rdfs:subClassOf obo:OBI_0600036 .
obo:OGMS_0000081 a rdfs:Class ;
rdfs:label "pathological derivation" ;
rdfs:comment "A pathological bodily process in which matter is reorganized in such a way as to give rise to new pathological formations which take the place of entities existing earlier."@en ;
rdfs:subClassOf obo:OGMS_0000061 .
obo:REO_0000687 a rdfs:Class ;
rdfs:label "synthetic homo-polyamino acid" ;
rdfs:comment "a synthetic polyamino acid made up of a single amino acid residue as the repeating unit" ;
rdfs:subClassOf obo:REO_0000686 .
obo:CL_0002141 a rdfs:Class ;
rdfs:label "active chief cell of parathyroid gland" ;
rdfs:comment "A parathyroid chief cell that is actively secreting hormone. Have large Golgi complexes with numerous vesicles and small membrane-bound granules; secretory granules are rare, cytoplasmic glycogen sparse, much of the cytoplasm being occupied by flat sacs of granular endoplasmic reticulum in parallel arrays; in normal humans, inactive chief cells outnumber active chief cells in a ratio of 3-5:1" ;
rdfs:subClassOf obo:CL_0000446 .
obo:CHEBI_30009 a rdfs:Class ;
rdfs:label "L-isoleucine residue" ;
rdfs:subClassOf obo:CHEBI_33700 .
obo:CL_0005007 a rdfs:Class ;
rdfs:label "Kolmer-Agduhr neuron" ;
rdfs:comment "Kolmer-Agduhr neurons are ciliated GABAergic neurons that contact the central canal of the spinal cord and have ipsilateral ascending axons." ;
rdfs:subClassOf obo:CL_0005000 .
obo:CHEBI_33699 a rdfs:Class ;
rdfs:label "messenger RNA" ;
rdfs:comment "An RNA molecule that transfers the coding information for protein synthesis from the chromosomes to the ribosomes mRNA is formed from a DNA template by transcription. It may be a copy of a single gene or of several adjacent genes (polycistronic mRNA). On the ribosome, the sequence is converted into the programmed amino acid sequence through translation." ;
rdfs:subClassOf obo:CHEBI_33697 .
obo:CHEBI_2038 a rdfs:Class ;
rdfs:label "5-azacytidine" ;
rdfs:comment "A N-glycosyl-1,3,5-triazine that has formula C8H12N4O5." ;
rdfs:subClassOf obo:CHEBI_33838 , obo:REO_0000490 , obo:REO_0000853 , obo:REO_0000917 .
obo:IAO_0000314 a rdfs:Class ;
rdfs:label "document part"@en ;
rdfs:comment "an information content entity that is part of a document"@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:MOD_00078 a rdfs:Class ;
rdfs:label "omega-N-methyl-L-arginine" ;
rdfs:comment "A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine." ;
rdfs:subClassOf obo:MOD_00427 .
obo:OBI_0000684 a rdfs:Class ;
rdfs:label "specimen creation objective" ;
rdfs:comment "A specimen creation objective is to obtain a material entity for potential use as an input during an investigation" ;
rdfs:subClassOf obo:IAO_0000005 .
obo:REO_0000801 a rdfs:Class ;
rdfs:label "tunicamycin reagent" ;
rdfs:subClassOf obo:REO_0000201 , obo:REO_0000978 .
obo:CL_0002306 a rdfs:Class ;
rdfs:label "epithelial cell of proximal tubule" ;
rdfs:comment "An epithelial cell of the proximal tubule of the kidney." ;
rdfs:subClassOf obo:CL_0002078 .
obo:OBI_0000847 a rdfs:Class ;
rdfs:label "test substance role" ;
rdfs:comment "A role born by a material entity and realized in a process where the substance is used as specified as the independent variable for an investigation" ;
rdfs:subClassOf obo:REO_0000248 .
obo:CL_0000660 a rdfs:Class ;
rdfs:label "glycocalyx secreting cell" ;
rdfs:comment "An extracellular matrix secreting cell that secretes glycocalyx." ;
rdfs:subClassOf obo:CL_0000327 .
obo:REO_0000302 a rdfs:Class ;
rdfs:label "obsolete_experimental modification objective" ;
rdfs:comment "the objective of a material processing to make physical changes to a specified input material (whereby structural or compositional alterations are made), to produce some output that represents a modified version of the specified input material." ;
rdfs:subClassOf .
obo:IAO_0000098 a rdfs:Class ;
rdfs:label "data format specification"@en ;
rdfs:subClassOf obo:IAO_0000033 .
obo:REO_0000492 a rdfs:Class ;
rdfs:label "modified nucleoside" ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:CL_0002061 a rdfs:Class ;
rdfs:label "T-helper 9 cell" ;
rdfs:comment "A T-helper cell that is characterized by secreting interleukin 9 and responding to helminth infections. This cell-type can derives from Th2 cells in the presence of TGF-beta and interleukin 4. TH2 cytokine production is surpressed." ;
rdfs:subClassOf obo:CL_0000492 .
obo:NCBITaxon_10407 a rdfs:Class ;
rdfs:label "Hepatitis B virus" ;
rdfs:subClassOf obo:NCBITaxon_10404 .
obo:CARO_0000072 a rdfs:Class ;
rdfs:label "cavitated compound organ" ;
rdfs:comment "Compound organ that contains one or more macroscopic anatomical spaces." ;
rdfs:subClassOf obo:CARO_0000024 .
obo:CL_0001017 a rdfs:Class ;
rdfs:label "mature CD1a-positive Langerhans cell" ;
rdfs:comment "Mature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive." ;
rdfs:subClassOf obo:CL_0001014 .
obo:REO_0000743 a rdfs:Class ;
rdfs:label "obsolete_transgenomic sequence 2" ;
rdfs:comment "a nucleic acid sequence that is encoded by a 'foreign', heritable nucleic acid (ie the physical nucleic acid bearing this sequence is experimentally added to a host cell), where the sequence of this nucleic acid is not represented in a reference genome of the host cell's source organism." ;
rdfs:subClassOf obo:REO_0000737 .
obo:OBI_0000377 a rdfs:Class ;
rdfs:label "perturb function"@en ;
rdfs:comment "A perturb function is a function that disrupts the normal function of a system induced through either internal or external means. External means of perturbation include: (1) displacement fields in the physical sense - e.g., temperature change, osmotic shock, pressure change; (2) application of small molecules such as drugs or toxins to perturb the function of specific pathways or application of surfactants to perturb the normal function of plasma membrane. Internal means of perturbation include: (1) manipulation of gene function via gene knockout or transcript knockdown via RNAi; (2) directed genetic mutation leading to minimal aa alterations that interfere with peptide function."@en ;
rdfs:subClassOf .
obo:CL_0002205 a rdfs:Class ;
rdfs:label "brush cell of lobular bronchiole" ;
rdfs:comment "A brush cell found in the epithelium of lobular bronchiole." ;
rdfs:subClassOf obo:CL_0002075 .
obo:CL_0002097 a rdfs:Class ;
rdfs:label "cortical cell of adrenal gland" ;
rdfs:comment "A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol." ;
rdfs:subClassOf obo:CL_0002078 .
obo:CL_0000834 a rdfs:Class ;
rdfs:label "neutrophil progenitor cell" ;
rdfs:comment "A progenitor cell of the neutrophil lineage." ;
rdfs:subClassOf obo:CL_0002191 .
obo:CL_0001014 a rdfs:Class ;
rdfs:label "CD1a-positive Langerhans cell" ;
rdfs:comment "CD1a-positive Langerhans cell is a Langerhans_cell that is CD1a-positive and CD324-positive." ;
rdfs:subClassOf obo:CL_0000453 .
obo:CL_0000700 a rdfs:Class ;
rdfs:label "dopaminergic neuron" ;
rdfs:comment "A neuron that releases dopamine as a neurotransmitter." ;
rdfs:subClassOf obo:CL_0000107 .
obo:NCBITaxon_9522 a rdfs:Class ;
rdfs:label "Callicebus" ;
rdfs:subClassOf obo:NCBITaxon_9443 .
obo:CL_0005000 a rdfs:Class ;
rdfs:label "spinal cord interneuron" ;
rdfs:comment "A CNS interneuron located in the spinal cord." ;
rdfs:subClassOf obo:CL_0000402 .
obo:CL_0000944 a rdfs:Class ;
rdfs:label "Be2 cell" ;
rdfs:comment "A Be cell that facilitates development of T-helper 2 (Th2) phenotype T cells, and secretes high levels of interleukin-2, interleukin-10, interleukin-4, and interleukin-6." ;
rdfs:subClassOf obo:CL_0000968 .
obo:SO_1000027 a rdfs:Class ;
rdfs:label "G_to_T_transversion" ;
rdfs:comment "A transversion from guanine to thymine." ;
rdfs:subClassOf obo:SO_1000023 .
obo:NCBITaxon_9031 a rdfs:Class ;
rdfs:label "Gallus gallus" ;
rdfs:subClassOf obo:NCBITaxon_8782 .
obo:REO_0000558 a rdfs:Class ;
rdfs:label "obsolete_lipid macromolecule reagent" ;
rdfs:comment "a lipid reagent that contains one or more long hydrocarbon chains, comprised primarily of a repeating carbon backbone saturted with bonds to hydrogen, or unsaturated and containing C=C double bonds. While technincally not macromolecules in the sense that they are not polymers comprised of repeating monomeric subunits, the repeating structure in the hydrocarbon chain resembles this feature of macromolecules." ;
rdfs:subClassOf .
obo:NCBITaxon_4754 a rdfs:Class ;
rdfs:label "Pneumocystis carinii" ;
rdfs:subClassOf obo:NCBITaxon_4751 .
obo:REO_0000736 a rdfs:Class ;
rdfs:label "transfection agent role" ;
rdfs:comment "a reagent role inhereing in some molecular entity that is used to deliver foreign material (typically DNA) into a cell or organism." ;
rdfs:subClassOf obo:REO_0000001 .
obo:CL_0000529 a rdfs:Class ;
rdfs:label "pigmented epithelial cell" ;
rdfs:subClassOf obo:CL_0000710 .
obo:REO_0000699 a rdfs:Class ;
rdfs:label "social role" ;
rdfs:comment "a role that inheres in a bearer in virtue of its context in a social order or set of conventions, that is conferred through the intentions of one or more social agents. A social role can be gained 'actively' by an agent through the agents own actions or intentions (an 'achieved role'), or 'passively' by an entity as a result of the bearer being assigned the role by some external agent or social convention that specifies some intended use by the agent or some status conferred by the agent (an 'ascribed role')." ;
rdfs:subClassOf .
obo:REO_0000439 a rdfs:Class ;
rdfs:label "bioactive" ;
rdfs:comment "a disposition to interact with, be processed by, or affect the function or activity of one or more biological molecules in the context of a cell, tissue, or organism" ;
rdfs:subClassOf .
obo:MOD_00237 a rdfs:Class ;
rdfs:label "L-beta-methylthioaspartic acid" ;
rdfs:comment "A protein modification that effectively converts an L-aspartic acid residue to L-beta-methylthioaspartic acid." ;
rdfs:subClassOf obo:PR_000025513 .
obo:REO_0000895 a rdfs:Class ;
rdfs:label "carbohydrate group" ;
rdfs:comment "an organic chemical group that consists of some carbohydrate moiety derived from a carbohydrate molecular entity" ;
rdfs:subClassOf obo:CHEBI_33247 , obo:REO_0000900 .
obo:CL_1000083 a rdfs:Class ;
rdfs:label "stratified keratinized epithelial stem cell" ;
rdfs:subClassOf obo:CL_0000357 .
obo:REO_0000118 a rdfs:Class ;
rdfs:label "Huntington gene"@en ;
rdfs:comment "a gene that includes all of the sequence elements in a geneome necessary to encode a functional transcript that can be translated into a Huntingtin protein by de novo ribosome-mediated translation." ;
rdfs:subClassOf obo:SO_0000704 .
obo:MOD_00814 a rdfs:Class ;
rdfs:label "O-xylosyl-L-serine" ;
rdfs:comment "A protein modification that effectively converts an L-serine residue to O3-xylosylserine." ;
rdfs:subClassOf obo:MOD_00693 .
obo:CL_0002413 a rdfs:Class ;
rdfs:label "mature Vgamma1.1-positive, Vdelta6.3-negative thymocyte" ;
rdfs:comment "A Vgamma1.1-positive, Vdelta6.3-negative thymocyte that is CD24-negative." ;
rdfs:subClassOf obo:CL_0002411 .
obo:REO_0000780 a rdfs:Class ;
rdfs:label "overlapping peptide peptide library" ;
rdfs:comment "A peptide library in which peptide sequences are engineered to exhibit a specified degree of overlap with other peptides in the library. The library generation process is characterized by two parameters, fragment length and offset number, each library is generated by breaking the original protein or peptide into many equal-length overlapping fragment, each has 8 to 20 residues in size." ;
rdfs:subClassOf obo:REO_0000777 .
obo:REO_0000279 a rdfs:Class ;
rdfs:label "obsolete_colorimetric reporter" ;
rdfs:subClassOf obo:REO_0000195 .
obo:CL_0000059 a rdfs:Class ;
rdfs:label "ameloblast" ;
rdfs:comment "Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell." ;
rdfs:subClassOf obo:CL_0002159 .
obo:CL_0002219 a rdfs:Class ;
rdfs:label "anchoring trophoblasts" ;
rdfs:comment "A trophoblast found at the junction of the placenta. This cell type makes a unique fibronectin-trophouteronectin junction that helps mediate attachment of the placenta to the uterus. This cell type is also found junction of the chorion layer of the external membranes and the decidua." ;
rdfs:subClassOf obo:CL_0000351 .
obo:CL_0000204 a rdfs:Class ;
rdfs:label "acceleration receptive cell" ;
rdfs:subClassOf obo:CL_0000006 .
obo:OBI_0100055 a rdfs:Class ;
rdfs:label "cell line cell"@en ;
rdfs:comment "A material entity that represents generations of a primary culture."@en ;
rdfs:subClassOf .
obo:CL_0000682 a rdfs:Class ;
rdfs:label "M cell" ;
rdfs:comment "An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes." ;
rdfs:subClassOf obo:CL_0000066 .
obo:CHEBI_16516 a rdfs:Class ;
rdfs:label "2'-deoxyribonucleoside triphosphate" ;
rdfs:subClassOf obo:CHEBI_17326 .
obo:REO_0000587 a rdfs:Class ;
rdfs:label "obsolete_B cell receptor complex" ;
rdfs:subClassOf .
obo:CL_0000955 a rdfs:Class ;
rdfs:label "pre-B-II cell" ;
rdfs:comment "A pre-B-II cell is a precursor B cell that expresses immunoglobulin mu heavy chain (IgHmu+), and lack expression of CD34, TdT, immunoglobulin kappa light chain and immunoglobulin lambda light chain." ;
rdfs:subClassOf obo:CL_0000817 .
obo:PATO_0001241 a rdfs:Class ;
rdfs:label "physical object quality" ;
rdfs:comment "A quality which inheres in a continuant." ;
rdfs:subClassOf .
obo:REO_0000946 a rdfs:Class ;
rdfs:label "natural genome" ;
rdfs:comment "a sequence collection representing the naturally-occuring genome of a cell or virion, that not been experimentally modified to contain specified mutations, insertions, deletions, epi-chromosomal elements, etc" ;
rdfs:subClassOf obo:SO_0001026 .
obo:CL_0000137 a rdfs:Class ;
rdfs:label "osteocyte" ;
rdfs:comment "A mature osteoblast that has become embedded in the bone matrix. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi." ;
rdfs:subClassOf obo:CL_0002320 .
obo:CL_0000839 a rdfs:Class ;
rdfs:label "myeloid lineage restricted progenitor cell" ;
rdfs:comment "A progenitor cell restricted to the myeloid lineage." ;
rdfs:subClassOf obo:CL_0002031 .
obo:OBI_0000113 a rdfs:Class ;
rdfs:label "sequence feature identification objective"@en ;
rdfs:comment "Sequence_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features exhibited at the level of a macromolecular sequence, e.g. nucleic acid, protein, polysaccharide."@en ;
rdfs:subClassOf obo:OBI_0000015 .
obo:CL_0002050 a rdfs:Class ;
rdfs:label "Fraction C' precursor B cell" ;
rdfs:comment "A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive." ;
rdfs:subClassOf obo:CL_0000817 .
obo:SO_1000048 a rdfs:Class ;
rdfs:label "reciprocal_chromosomal_translocation" ;
rdfs:comment "A chromosomal translocation with two breaks; two chromosome segments have simply been exchanged." ;
rdfs:subClassOf obo:SO_1000044 .
obo:CL_0002340 a rdfs:Class ;
rdfs:label "luminal cell of prostate epithelium" ;
rdfs:comment "The exocrine cell of the prostate, this epithelial cell secretes prostatic acid phosphotase and PSA, and is dependent on androgen hormones for survival." ;
rdfs:subClassOf obo:CL_0002231 .
obo:REO_0000799 a rdfs:Class ;
rdfs:label "L-methionine[S35]" ;
rdfs:comment "a methionine amino acid engineered to contain the sulfur-35 radioisotope" ;
rdfs:subClassOf obo:CHEBI_16643 , obo:REO_0000292 , obo:REO_0000556 .
obo:CL_0000749 a rdfs:Class ;
rdfs:label "ON-bipolar cell" ;
rdfs:comment "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors." ;
rdfs:subClassOf obo:CL_0000748 .
obo:CL_0000162 a rdfs:Class ;
rdfs:label "parietal cell" ;
rdfs:comment "A large, oval stomach epithelial cell with a central nucleus; source of gastric acid. Secretes HCl." ;
rdfs:subClassOf obo:CL_0002178 .
obo:CHEBI_37971 a rdfs:Class ;
rdfs:label "phosphorus-31 atom" ;
rdfs:comment "The stable isotope of phosphorus with relative atomic mass 30.973762 and nuclear spin (1)/2." ;
rdfs:subClassOf obo:CHEBI_28659 .
obo:CHEBI_17196 a rdfs:Class ;
rdfs:label "L-asparagine" ;
rdfs:comment "An optically active form of asparagine having L-configuration." ;
rdfs:subClassOf obo:REO_0000545 .
obo:REO_0000839 a rdfs:Class ;
rdfs:label "PNA nucleotide" ;
rdfs:subClassOf obo:REO_0000489 .
obo:REO_0000338 a rdfs:Class ;
rdfs:label "molecular tracker role" ;
rdfs:comment "a molecular label role inhering in a molecular entity that is not capable of producing a detectable signal (such that to allow detection of some target analyte, it must associate with some molecular reporter that does produce a detectable signel)" ;
rdfs:subClassOf obo:REO_0000171 .
obo:CHEBI_29967 a rdfs:Class ;
rdfs:label "L-lysine residue" ;
rdfs:subClassOf obo:CHEBI_33700 .
obo:UBERON_0000107 a rdfs:Class ;
rdfs:label "cleavage stage" ;
rdfs:comment "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." ;
rdfs:subClassOf obo:UBERON_0000067 .
obo:CL_0001006 a rdfs:Class ;
rdfs:label "dermal dendritic cell" ;
rdfs:comment "Dermal dendritic cell is a conventional dendritic cell that is CD11b-positive, CD205-positive and CD8 alpha-negative." ;
rdfs:subClassOf obo:CL_0000990 .
obo:CL_1000191 a rdfs:Class ;
rdfs:label "pillar cell" ;
rdfs:comment "A rod-like cell in the inner ear, having their heads joined and their bases on the basilar membrane widely separated so as to form a spiral tunnel known as the tunnel of Corti." ;
rdfs:subClassOf obo:CL_0002315 .
obo:CHEBI_17561 a rdfs:Class ;
rdfs:label "L-cysteine" ;
rdfs:comment "An optically active form of cysteine having L-configuration." ;
rdfs:subClassOf obo:REO_0000545 .
obo:REO_0000107 a rdfs:Class ;
rdfs:label "myeloma"@en ;
rdfs:comment "a neoplasm resulting from the uncontrolled proliferation of plasma cells, a type of white blood cell normally responsible for the production of antibodies." ;
rdfs:subClassOf obo:MPATH_218 .
obo:CL_0000868 a rdfs:Class ;
rdfs:label "lymph node macrophage" ;
rdfs:comment "A secondary lymphoid organ macrophage found in a lymph node. This cell is CD169-high." ;
rdfs:subClassOf obo:CL_0000867 .
obo:IAO_0000415 a rdfs:Class ;
rdfs:label "hypothesis textual entity"@en ;
rdfs:comment "A textual entity that expresses an assertion that is intended to be tested."@en ;
rdfs:subClassOf obo:IAO_0000300 .
obo:CARO_0000011 a rdfs:Class ;
rdfs:label "anatomical system" ;
rdfs:comment "Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity." ;
rdfs:subClassOf obo:CARO_0000054 .
obo:CL_0000996 a rdfs:Class ;
rdfs:label "mature CD11c-negative plasmacytoid dendritic cell" ;
rdfs:comment "Mature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive." ;
rdfs:subClassOf obo:CL_0000991 .
obo:CL_0000536 a rdfs:Class ;
rdfs:label "secondary motor neuron" ;
rdfs:subClassOf obo:CL_0000535 .
obo:IAO_0000129 a rdfs:Class ;
rdfs:label "version number"@en ;
rdfs:comment "A version number is an information content entity which is a sequence of characters borne by part of each of a class of manufactured products or its packaging and indicates its order within a set of other products having the same name."@en ;
rdfs:subClassOf obo:IAO_0000028 .
obo:REO_0000547 a rdfs:Class ;
rdfs:label "incorporant disposition" ;
rdfs:comment "a disposition to be incorporated into the output of some synthetic process (be it an endogenous biological process or a planned process), such that the output derives some significant portion of material from the bearer of the incorporant role." ;
rdfs:subClassOf .
obo:CL_0000832 a rdfs:Class ;
rdfs:label "eosinophilic myeloblast" ;
rdfs:comment "A myeloblast committed to the eosinophil lineage." ;
rdfs:subClassOf obo:CL_0000835 .
obo:CLO_0000000 a rdfs:Class ;
rdfs:label "cell line culturing" ;
rdfs:comment "a processual entity that is the collection of all processes directly involved in maintenance of an active cell culture, following its initial establishment " ;
rdfs:subClassOf obo:REO_0000135 , obo:REO_0000389 .
obo:CL_0000802 a rdfs:Class ;
rdfs:label "CD8-alpha alpha positive, gamma-delta intraepithelial T cell" ;
rdfs:comment "A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive." ;
rdfs:subClassOf obo:CL_0000801 .
obo:IAO_0000178 a rdfs:Class ;
rdfs:label "material information bearer"@en ;
rdfs:comment "An information bearer is a material_entity in which a concretization of an information content entity inheres."@en ;
rdfs:subClassOf .
obo:CHEBI_16857 a rdfs:Class ;
rdfs:label "L-threonine" ;
rdfs:comment "An optically active form of threonine having L-configuration." ;
rdfs:subClassOf obo:REO_0000545 .
obo:REO_0000428 a rdfs:Class ;
rdfs:label "non-metal elemental molecule reagent" ;
rdfs:comment "an elemental molecule that is comprised only of a single type of non-metal atom and that bears a reagent role" ;
rdfs:subClassOf obo:REO_0000358 , obo:REO_0000791 .
obo:REO_0000044 a rdfs:Class ;
rdfs:label "RNA primer"@en ;
rdfs:comment "a RNA oligonucleotide that binds to some complementary nucleic acid template to serve as a starting point for nucleic acid synthesis" ;
rdfs:subClassOf obo:REO_0000035 , obo:REO_0000094 .
obo:CL_0000783 a rdfs:Class ;
rdfs:label "multinucleated phagocyte" ;
rdfs:comment "A phagocyte formed by the fusion of mononuclear phagocytes." ;
rdfs:subClassOf obo:CL_0000518 .
obo:CL_0002118 a rdfs:Class ;
rdfs:label "CD38-negative IgG-negative class switched memory B cell" ;
rdfs:comment "A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative." ;
rdfs:subClassOf obo:CL_0002117 .
obo:CL_0002270 a rdfs:Class ;
rdfs:label "type EC2 enteroendocrine cell" ;
rdfs:comment "A type EC enteroendocrine cell in the duodenum and jejunum that stores and secretes motilin and 5-hydroxytryptamine." ;
rdfs:subClassOf obo:CL_0000577 .
obo:CL_0002320 a rdfs:Class ;
rdfs:label "connective tissue cell" ;
rdfs:comment "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." ;
rdfs:subClassOf obo:CL_0002371 .
obo:REO_0000545 a rdfs:Class ;
rdfs:label "canonical amino acid" ;
rdfs:comment "an alpha amino acid that is one of the set of all alpha-amino acids that naturally are incorporated into protein chains by the ribosome." ;
rdfs:subClassOf obo:CHEBI_33709 , obo:REO_0000908 .
obo:REO_0000378 a rdfs:Class ;
rdfs:label "selection technique" ;
rdfs:comment "a material processing technique with the objective to separate a subset of some collection of material entities away from some total input collection, based on a specified attribute or set of attributes borne by the selected entities, and such that only the selected entities will be used for some subsequent planned process" ;
rdfs:subClassOf obo:OBI_0600014 , obo:REO_0000159 .
obo:OBI_0302732 a rdfs:Class ;
rdfs:label "solvent role"@en ;
rdfs:comment "solvent role is a role which inheres in a molecular entity capable of ensuring the dissolution of another chemical entity and realized by the process of solvation"@en ;
rdfs:subClassOf obo:REO_0000001 .
obo:REO_0000520 a rdfs:Class ;
rdfs:label "unmodified multicellular organism cell in vivo" ;
rdfs:comment "an unmodified multicellular organism cell that is part of an organism" ;
rdfs:subClassOf obo:REO_0000531 , obo:REO_0000701 .
obo:CL_0000188 a rdfs:Class ;
rdfs:label "skeletal muscle cell" ;
rdfs:comment "A somatic cell located in skeletal muscle." ;
rdfs:subClassOf obo:CL_0000737 .
obo:NCBITaxon_7664 a rdfs:Class ;
rdfs:label "Strongylocentrotus" ;
rdfs:subClassOf obo:NCBITaxon_131567 .
obo:REO_0000624 a rdfs:Class ;
rdfs:label "IgG2c polyclonal antibody reagent" ;
rdfs:subClassOf .
obo:CL_0000357 a rdfs:Class ;
rdfs:label "stratified epithelial stem cell" ;
rdfs:subClassOf obo:CL_0000036 .
obo:CL_0000972 a rdfs:Class ;
rdfs:label "class switched memory B cell" ;
rdfs:comment "A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are usually CD27-positive and have either IgG, IgE, or IgA on the cell surface." ;
rdfs:subClassOf obo:CL_0000787 .
obo:CL_0000307 a rdfs:Class ;
rdfs:label "tracheal epithelial cell" ;
rdfs:comment "An epithelial cell found in the trachea." ;
rdfs:subClassOf obo:CL_0002202 .
obo:REO_0000694 a rdfs:Class ;
rdfs:label "obsolete_bioengineering technique" ;
rdfs:comment "a material processing technique whereby a natural biological process is intentionally and specifically triggered or manipulated by some agent to produce some specified product that is output from this biological process" ;
rdfs:subClassOf .
obo:CL_0002402 a rdfs:Class ;
rdfs:label "Peyer's patch B cell" ;
rdfs:comment "A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative." ;
rdfs:subClassOf obo:CL_0000822 .
obo:NCBITaxon_2157 a rdfs:Class ;
rdfs:label "Archaea" ;
rdfs:subClassOf obo:ERO_0000581 .
obo:REO_0000747 a rdfs:Class ;
rdfs:label "stem cell-derived cell line" ;
rdfs:comment "A cell line that is derived from a stem cell." ;
rdfs:subClassOf obo:CLO_0000019 .
obo:CL_0000820 a rdfs:Class ;
rdfs:label "B-1a B cell" ;
rdfs:comment "A B-1 B cell that has the phenotype CD5-positive." ;
rdfs:subClassOf obo:CL_0000819 .
obo:REO_0000029 a rdfs:Class ;
rdfs:label "yeast two-hybrid construct" ;
rdfs:comment "A construct used for yeast two hybrid screening assays, which is engineered to express a protein of interest fused to either the DNA-binding domain (BD) fragment or activation domain (AD) of a transcription factor. Yeast two hybrid constructs are typically plasmids or phagemids." ;
rdfs:subClassOf obo:REO_0000096 .
obo:CL_0000693 a rdfs:Class ;
rdfs:label "neuroglioform cell" ;
rdfs:comment "A stellate interneuron having 7-10 dendrites that may branch." ;
rdfs:subClassOf obo:CL_0000691 .
obo:REO_0000292 a rdfs:Class ;
rdfs:label "radioactive covalent reporter" ;
rdfs:subClassOf obo:REO_0000268 , obo:REO_0000285 .
obo:CL_0000881 a rdfs:Class ;
rdfs:label "perivascular macrophage" ;
rdfs:comment "A central nervous system macrophage found in small blood vessels in the brain. Markers include CD14+CD16+CD163+." ;
rdfs:subClassOf obo:CL_0000878 .
obo:CL_0002296 a rdfs:Class ;
rdfs:label "type-4 epithelial cell of thymus" ;
rdfs:comment "An epithelial cell with high nuclear and cytoplasmic electron-density. This cell type is found in the deeper portions of the cortex but is more abundant in the medulla of the thymus." ;
rdfs:subClassOf obo:CL_0002365 .
obo:CL_0000807 a rdfs:Class ;
rdfs:label "DN3 thymocyte" ;
rdfs:comment "A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain." ;
rdfs:subClassOf obo:CL_0000893 .
obo:REO_0000237 a rdfs:Class ;
rdfs:label "obsolete_minor incorporant role" ;
rdfs:comment "an incorporant role inhering in an input material entity gained through an agent's intention for it be input into some material processing where it will not contribute the most significant amount of material to the composition of the specified output relative to other incorporants, and realized in the exection of such a material processing event" ;
rdfs:subClassOf .
obo:REO_0000613 a rdfs:Class ;
rdfs:label "IgE immunoglobulin complex, circulating" ;
rdfs:subClassOf obo:GO_0042571 .
obo:CHEBI_33238 a rdfs:Class ;
rdfs:label "monoatomic entity" ;
rdfs:comment "A monoatomic entity is a molecular entity consisting of a single atom." ;
rdfs:subClassOf obo:CHEBI_33259 .
obo:REO_0000356 a rdfs:Class ;
rdfs:label "obsolete_buffer role" ;
rdfs:comment """a reagent role that exploits some buffering disposition in its realization
through the process of buffering""" ;
rdfs:subClassOf .
obo:CL_0000418 a rdfs:Class ;
rdfs:label "arcade cell" ;
rdfs:comment "An epithelial cell found in C. elegans that firmly hold the outer body wall and the lips to the inner cylinder of the pharynx in a manner that keeps these organs from breaking apart, while still giving each organ freedom of movement during feeding." ;
rdfs:subClassOf obo:CL_0000066 .
obo:CL_0002216 a rdfs:Class ;
rdfs:label "intermediate muscle cell" ;
rdfs:comment "An intermediate muscle cell that has characteristics of both fast and slow muscle cells." ;
rdfs:subClassOf obo:CL_0000188 .
obo:CHEBI_37985 a rdfs:Class ;
rdfs:label "sulfur-38 atom" ;
rdfs:comment "The radioactive isotope of sulfur with relative atomic mass 37.97116 and half-life of 170.3 min." ;
rdfs:subClassOf obo:CHEBI_26833 .
obo:CL_0002439 a rdfs:Class ;
rdfs:label "NKGA2-positive natural killer cell" ;
rdfs:comment "A NK1.1-positive T cell that is NKGA2-positive." ;
rdfs:subClassOf obo:CL_0002438 .
obo:CHEBI_37586 a rdfs:Class ;
rdfs:label "sodium phosphate" ;
rdfs:subClassOf obo:CHEBI_24839 .
obo:GO_0006351 a rdfs:Class ;
rdfs:label "transcription, DNA-dependent" ;
rdfs:comment "The cellular synthesis of RNA on a template of DNA." ;
rdfs:subClassOf obo:GO_0008150 .
obo:REO_0000420 a rdfs:Class ;
rdfs:label "high molecular weight" ;
rdfs:comment "a chemical mass quality inhereing in a molecular entity with a molecular weight of greater than 800 daltons." ;
rdfs:subClassOf obo:REO_0000417 .
obo:CL_0000518 a rdfs:Class ;
rdfs:label "phagocyte (sensu Vertebrata)" ;
rdfs:comment "A phagocyte in vertebrates that is able to phagocytosis." ;
rdfs:subClassOf obo:CL_0000766 .
obo:CHEBI_25359 a rdfs:Class ;
rdfs:label "modified amino acid" ;
rdfs:comment """Note that here the notion of 'modified' is distinct from our notion of 'experimentally modified' (where the latter holds that there is some experimental modification process that takes as input some unmodified material entity and outputs a modified variant of this same material entity). Being 'modified' merely reflects some physical variation with respect to some reference object or structure- so modified amino acids can be synthesized de novo, such that there is not necessarily some experimental modification process that takes as input some unmodified amino acid and outputs a modified variant.
For now we have only claimed the 'reference' set of unmodified amino acids to contain the set of canonical amino acid structures. As canonical amino acids are defined strictly by their molecular structures, any modifications will result in a modified, non-canonical amino acid (e.g. even a natural modification such as a phosphorylation).""" ;
rdfs:subClassOf obo:REO_0000576 .
a rdf:Property ;
rdfs:label "has functional parent" ;
rdfs:comment """Used to denote the relationship between two molecular entities (or classes of entities), one of which possesses one or more chacteristic groups from which the other CAN be derived by functional modification.
Definition: A has_functional_parent B if and only if given any a, a instantiates A , has molecular graph ag and a obo:has_part some functional group fg, then there is some b such that b instantiates B, has molecular graph bg and has functional group fgā such that bg is the result of a graph transformation process on ag resulting in the conversion of fg into fgā.""" ;
rdfs:range ;
rdfs:subPropertyOf obo:REO_0000941 .
obo:GO_0042648 a rdfs:Class ;
rdfs:label "chloroplast chromosome" ;
rdfs:comment "A circular DNA molecule containing chloroplast encoded genes." ;
rdfs:subClassOf obo:GO_0009508 .
obo:REO_0000485 a rdfs:Class ;
rdfs:label "target of structural rearrangement role" ;
rdfs:comment "a role realized by a planned process in which the bearer is physically modified through the structural re-arrangement of its existing components. No new material is physically associated with the bearer, and no material is removed from the bearer in this process (ie no net gain or loss of matter)." ;
rdfs:subClassOf obo:REO_0000828 .
obo:CL_0000129 a rdfs:Class ;
rdfs:label "microglial cell" ;
rdfs:comment "A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive." ;
rdfs:subClassOf obo:CL_0000878 .
obo:CL_0000544 a rdfs:Class ;
rdfs:label "slowly adapting mechanoreceptor cell" ;
rdfs:subClassOf obo:CL_0000199 .
obo:CL_0000919 a rdfs:Class ;
rdfs:label "CD8-positive, CD25-positive, alpha-beta regulatory T cell" ;
rdfs:comment "A CD8-positive alpha beta-positive T cell with the phenotype FoxP3-positive and having suppressor function." ;
rdfs:subClassOf obo:CL_0000795 .
obo:CL_0000947 a rdfs:Class ;
rdfs:label "IgE plasma cell" ;
rdfs:comment "A long lived plasma cell that secretes IgE." ;
rdfs:subClassOf obo:CL_0000974 .
obo:CL_0000810 a rdfs:Class ;
rdfs:label "CD4-positive, alpha-beta thymocyte" ;
rdfs:comment "An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative." ;
rdfs:subClassOf obo:CL_0000893 .
obo:SO_0001028 a rdfs:Class ;
rdfs:label "diplotype" ;
rdfs:comment "A diplotype is a pair of haplotypes from a given individual. It is a genotype where the phase is known." ;
rdfs:subClassOf obo:SO_0001507 .
obo:REO_0000534 a rdfs:Class ;
rdfs:label "obsolete_molecular quality" ;
rdfs:comment "A quality which inheres in a molecular entity, a single molecule, atom, ion, radical etc." ;
rdfs:subClassOf .
obo:CL_0000312 a rdfs:Class ;
rdfs:label "keratinocyte" ;
rdfs:comment "An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell." ;
rdfs:subClassOf obo:CL_0000362 .
obo:CHEBI_17326 a rdfs:Class ;
rdfs:label "nucleoside triphosphate" ;
rdfs:comment "a nucleoside phosphate containing three phosphate groups bound to its sugar ring" ;
rdfs:subClassOf obo:CHEBI_25608 .
obo:CL_0000738 a rdfs:Class ;
rdfs:label "leukocyte" ;
rdfs:comment "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ;
rdfs:subClassOf obo:CL_0000988 .
obo:REO_0000727 a rdfs:Class ;
rdfs:label "organism library" ;
rdfs:comment "A reagent library consisting of a collection of organism reagents" ;
rdfs:subClassOf obo:REO_0000006 .
obo:CHEBI_36939 a rdfs:Class ;
rdfs:label "fluorine-18 atom" ;
rdfs:comment "The radioactive isotope of fluorine with relative atomic mass 18.000938. The longest-lived fluorine radionuclide with half-life of 109.77 min." ;
rdfs:subClassOf obo:CHEBI_24061 .
obo:REO_0000986 a rdfs:Class ;
rdfs:label "gene knock out" ;
rdfs:subClassOf obo:SO_1000032 .
obo:SO_1000032 a rdfs:Class ;
rdfs:label "indel" ;
rdfs:comment "A sequence alteration which included an insertion and a deletion, affecting 2 or more bases." ;
rdfs:subClassOf obo:SO_0001059 .
obo:IAO_0000327 a rdfs:Class ;
rdfs:label "table of contents"@en ;
rdfs:comment "A table that relates document parts to specific locations in a document (usually page numbers). This is also a document part (subsumption there should be inferred)."@en ;
rdfs:subClassOf obo:IAO_0000306 .
obo:CL_0005014 a rdfs:Class ;
rdfs:label "auditory epithelial support cell" ;
rdfs:comment "A non-sensory cell that extends from the basement membrane to the apical surface of the auditory epithelium and provides support for auditory hair cells." ;
rdfs:subClassOf obo:CL_0000710 .
obo:CHEBI_30011 a rdfs:Class ;
rdfs:label "L-glutamine residue" ;
rdfs:subClassOf obo:CHEBI_33700 .
obo:CHEBI_50860 a rdfs:Class ;
rdfs:label "organic molecular entity" ;
rdfs:comment "Any molecular entity that contains carbon." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:CL_0002407 a rdfs:Class ;
rdfs:label "mature Vgamma2-positive thymocyte" ;
rdfs:comment "A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4- negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus." ;
rdfs:subClassOf obo:CL_0002405 .
obo:REO_0000037 a rdfs:Class ;
rdfs:label "dsRNA oligonucleotide reagent" ;
rdfs:comment "an RNA interference oligonucleotide reagent comprised of complementary strands of RNA that form double-stranded duplexes, and can be processed through the RNAi pathway into short interfering RNA (siRNA) molecules used to silence target gene expression." ;
rdfs:subClassOf obo:REO_0000036 , obo:REO_0000518 .
obo:CL_0000496 a rdfs:Class ;
rdfs:label "green sensitive photoreceptor cell" ;
rdfs:comment "A photoreceptor cell that is sensitive to green light." ;
rdfs:subClassOf obo:CL_0000490 .
obo:REO_0000125 a rdfs:Class ;
rdfs:label "unicellular organism culture"@en ;
rdfs:comment "a cell culture consisting of unicellular organisms (e.g. bacteria, yeast, protists) maintained in vitro" ;
rdfs:subClassOf obo:OBI_0100060 .
obo:REO_0000180 a rdfs:Class ;
rdfs:label "obsolete_tracker labeling technique"@en ;
rdfs:subClassOf .
obo:UBERON_0008264 a rdfs:Class ;
rdfs:label "echinopluteus larval stage" ;
rdfs:comment "Larval stage in echinoderms characterized by a planktonic and feeding larval form that possesses limb-like outgrowths bearing ciliated bands." ;
rdfs:subClassOf obo:UBERON_0000069 .
obo:CL_0000902 a rdfs:Class ;
rdfs:label "induced T-regulatory cell" ;
rdfs:comment "CD4-positive alpha-beta T cell with the phenotype CD25-positive, CTLA-4-positive, and FoxP3-positive with regulatory function." ;
rdfs:subClassOf obo:CL_0000792 .
obo:CL_0002260 a rdfs:Class ;
rdfs:label "epithelial cell of parathyroid gland" ;
rdfs:comment "An epithelial cell of the parathyroid gland." ;
rdfs:subClassOf obo:CL_0002076 .
obo:REO_0000975 a rdfs:Class ;
rdfs:label "plasmid construct" ;
rdfs:comment "A plasmid engineered in vitro to be capable of delivering, replicating, and often expressing exogenous DNA sequences in some host cell. These sequences, called 'construct inserts' or 'cloned inserts', are are maintained in some host cell through the action of various functional elements in the construct that facilitate plasmid amplification, selection, and antibiotic resistance." ;
rdfs:subClassOf obo:OBI_0000430 , obo:REO_0000007 .
obo:CL_0000794 a rdfs:Class ;
rdfs:label "CD8-positive, alpha-beta cytotoxic T cell" ;
rdfs:comment "A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive." ;
rdfs:subClassOf obo:CL_0000910 .
obo:CL_0002178 a rdfs:Class ;
rdfs:label "epithelial cell of stomach" ;
rdfs:comment "An epithelial cell found in the lining of the stomach." ;
rdfs:subClassOf obo:CL_0002251 .
obo:SO_1000021 a rdfs:Class ;
rdfs:label "T_to_A_transversion" ;
rdfs:comment "A transversion from T to A." ;
rdfs:subClassOf obo:SO_1000018 .
obo:CL_0000010 a rdfs:Class ;
rdfs:label "cell culture cell" ;
rdfs:comment "A cell in vitro that is propagated as part of a cell culture." ;
rdfs:subClassOf obo:REO_0000131 , obo:REO_0000527 .
obo:OBI_0000645 a rdf:Property ;
rdfs:label "is grain of"@en ;
rdfs:comment "replace with BFO2:'is granular part of'?" ;
rdfs:range ;
rdfs:subPropertyOf .
obo:REO_0000156 a rdfs:Class ;
rdfs:label "genetically modified cell line"@en ;
rdfs:comment "an immortal cell line which has been intentionally modified through some genetic modification technique intended to alter the sequence of its genetic material, or introduce exogenous genetic material that is capable of being stably replicated and inherited through subsequent generations of cells." ;
rdfs:subClassOf obo:CLO_0000019 , obo:OBI_0001151 .
obo:PATO_0002182 a rdfs:Class ;
rdfs:label "molecular quality" ;
rdfs:comment "A quality which inheres in a molecular entity, a single molecule, atom, ion, radical etc." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:REO_0000149 a rdfs:Class ;
rdfs:label "transformed cell"@en ;
rdfs:comment "a cell that has undergone genetic modifications that confer upon it properties of cancer, including the capacity for uncontrolled growth, invasion into adjacent tissues, and metastasis to distant sites in the body. When cultured in vitro, transformed cells have the ability to replicate indefinitely." ;
rdfs:subClassOf obo:REO_0000371 .
obo:REO_0000189 a rdfs:Class ;
rdfs:label "obsolete_bioactive small molecule"@en ;
rdfs:comment "an organic molecule of low molecular weight, which is by definition not a polymer, and can interact with and affect the function or activity of one or more biological molecules in the context of a cell, tissue, or organism." ;
rdfs:subClassOf obo:REO_0000982 .
obo:NCBITaxon_7129 a rdfs:Class ;
rdfs:label "Manduca" ;
rdfs:subClassOf obo:NCBITaxon_7088 .
obo:CL_0002313 a rdfs:Class ;
rdfs:label "endocrine-paracrine cell of prostate gland" ;
rdfs:comment "An ecto-epithelial cell of the prostate gland that secretes hormones." ;
rdfs:subClassOf obo:CL_0002159 .
obo:SO_1000144 a rdfs:Class ;
rdfs:label "free_duplication" ;
rdfs:comment "A chromosome structure variation whereby the duplicated sequences are carried as a free centric element." ;
rdfs:subClassOf obo:SO_1000037 .
obo:CL_0000076 a rdfs:Class ;
rdfs:label "squamous epithelial cell" ;
rdfs:subClassOf obo:CL_0000066 .
obo:CL_0000547 a rdfs:Class ;
rdfs:label "proerythroblast" ;
rdfs:comment "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." ;
rdfs:subClassOf obo:CL_0000764 .
obo:CL_0000429 a rdfs:Class ;
rdfs:label "imaginal disc cell" ;
rdfs:subClassOf obo:CL_0000146 .
obo:NCBITaxon_10255 a rdfs:Class ;
rdfs:label "Variola virus" ;
rdfs:subClassOf obo:NCBITaxon_10240 .
obo:CL_0002025 a rdfs:Class ;
rdfs:label "CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell" ;
rdfs:comment "A megakaryocyte progenitor cell that is CD34-positive, CD41-positive, and CD42-negative." ;
rdfs:subClassOf obo:CL_0000553 .
obo:IAO_0000006 a rdfs:Class ;
rdfs:label "narrative object"@en ;
rdfs:comment "A narrative object is an information content entity that is a set of propositions."@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:CHEBI_52631 a rdfs:Class ;
rdfs:label "iodine-127 atom" ;
rdfs:comment "The stable isotope of iodine with relative atomic mass 126.904468, 100 atom percent natural abundance and nuclear spin 5/2." ;
rdfs:subClassOf obo:CHEBI_24859 .
obo:IAO_0000308 a rdfs:Class ;
rdfs:label "figure"@en ;
rdfs:comment "An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something."@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:REO_0000863 a rdfs:Class ;
rdfs:label "uniform collection" ;
rdfs:comment "an object aggregate that is a collection of material entities that are of the same type and exhibit similar or identical structure " ;
rdfs:subClassOf .
obo:REO_0000077 a rdfs:Class ;
rdfs:label "gene knockdown function"@en ;
rdfs:comment "a perturb function that inheres in molecular entities that are directly capable of reducing expression levels of some target gene in eukaryotic cells, or in plasmids created to produce such molecules" ;
rdfs:subClassOf obo:OBI_0000377 .
obo:SO_0000567 a rdfs:Class ;
rdfs:label "inversion_derived_aneuploid_chromosome" ;
rdfs:comment "A chromosome may be generated by recombination between two inversions; presumed to have a deficiency or duplication at each end of the inversion." ;
rdfs:subClassOf obo:SO_0000550 .
obo:SO_1000038 a rdfs:Class ;
rdfs:label "intrachromosomal_duplication" ;
rdfs:comment "A duplication that occurred within a chromosome." ;
rdfs:subClassOf obo:SO_1000037 .
obo:REO_0000226 a rdfs:Class ;
rdfs:label "obsolete_DAPI" ;
rdfs:subClassOf .
obo:CL_0002201 a rdfs:Class ;
rdfs:label "renal beta-intercalated cell" ;
rdfs:comment "A renal intercalated cell that secretes base and reabsorbs acid in the coritcal collecting duct to mantain acid/base balance." ;
rdfs:subClassOf obo:CL_0005010 .
obo:CL_0002393 a rdfs:Class ;
rdfs:label "intermediate monocyte" ;
rdfs:comment "A monocyte that has characteristics of both patrolling and inflammatory monocytes." ;
rdfs:subClassOf obo:CL_0000576 .
obo:NCBITaxon_5658 a rdfs:Class ;
rdfs:label "Leishmania" ;
rdfs:subClassOf obo:NCBITaxon_33682 .
obo:NCBITaxon_9540 a rdfs:Class ;
rdfs:label "Macaca arctoides" ;
rdfs:subClassOf obo:NCBITaxon_9539 .
obo:IAO_0000028 a rdfs:Class ;
rdfs:label "symbol"@en ;
rdfs:comment "a smallish, word-like datum..."@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:CHEBI_17295 a rdfs:Class ;
rdfs:label "L-phenylalanine" ;
rdfs:comment "The L-enantiomer of phenylalanine." ;
rdfs:subClassOf obo:REO_0000545 .
obo:CL_0000115 a rdfs:Class ;
rdfs:label "endothelial cell" ;
rdfs:comment "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." ;
rdfs:subClassOf obo:CL_0002078 .
obo:REO_0000807 a rdfs:Class ;
rdfs:label "deoxyribonucleotide mix" ;
rdfs:comment "a reagent mixture that contains a mix of dNTP molecules (typically dATP, dCTP, dGTP, and dTTP to be used in PCR reactions)" ;
rdfs:subClassOf obo:CHEBI_60004 , obo:REO_0000806 .
obo:CARO_0000065 a rdfs:Class ;
rdfs:label "basal lamina" ;
rdfs:comment "Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue." ;
rdfs:subClassOf obo:CARO_0000040 .
obo:GO_0010467 a rdfs:Class ;
rdfs:label "gene expression" ;
rdfs:comment "The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CHEBI_33815 a rdfs:Class ;
rdfs:label "oxygen-18 atom" ;
rdfs:comment "The stable isotope of oxygen with relative atomic mass 17.999160 and 0.205 atom percent natural abundance." ;
rdfs:subClassOf obo:CHEBI_25805 .
obo:CL_0000821 a rdfs:Class ;
rdfs:label "B-1b B cell" ;
rdfs:comment "A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell." ;
rdfs:subClassOf obo:CL_0000819 .
obo:CL_0000985 a rdfs:Class ;
rdfs:label "IgG plasma cell" ;
rdfs:comment "A fully differentiated plasma cell that secretes IgG." ;
rdfs:subClassOf obo:CL_0000974 .
obo:CL_0002248 a rdfs:Class ;
rdfs:label "pluripotent stem cell" ;
rdfs:comment "A pluripotent stem cell has the ability to form cells from all three germ layers (ectoderm, mesoderm, and endoderm). However, unlike totipotent stem cells, they cell can not generate all the cells of the whole organism such as placenta." ;
rdfs:subClassOf obo:CL_0000723 .
obo:CL_0002432 a rdfs:Class ;
rdfs:label "CD24-positive, CD4 single-positive thymocyte" ;
rdfs:comment "A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor." ;
rdfs:subClassOf obo:CL_0000810 .
obo:REO_0000306 a rdfs:Class ;
rdfs:label "material sampling objective" ;
rdfs:subClassOf obo:REO_0000304 .
obo:CARO_0000055 a rdfs:Class ;
rdfs:label "multi-tissue structure" ;
rdfs:comment "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." ;
rdfs:subClassOf obo:CARO_0000003 .
obo:REO_0000345 a rdfs:Class ;
rdfs:label "obsoleted_RNA microarray" ;
rdfs:subClassOf .
obo:CL_0000936 a rdfs:Class ;
rdfs:label "early lymphoid progenitor" ;
rdfs:comment "A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative." ;
rdfs:subClassOf obo:CL_0000837 .
obo:OBI_0600042 a rdfs:Class ;
rdfs:label "recombinant plasmid cloning"@en ;
rdfs:comment "the insertion of a particular DNA fragment into a plasmid in order to make copies of a biomaterial"@en ;
rdfs:subClassOf obo:OBI_0600064 .
obo:CL_0002011 a rdfs:Class ;
rdfs:label "Kit-positive macrophage dendritic cell progenitor" ;
rdfs:comment "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative." ;
rdfs:subClassOf obo:CL_0002009 .
obo:MOD_00113 a rdfs:Class ;
rdfs:label "S-geranylgeranyl-L-cysteine" ;
rdfs:comment "A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine." ;
rdfs:subClassOf obo:MOD_00703 .
obo:CL_0000043 a rdfs:Class ;
rdfs:label "mature basophil" ;
rdfs:comment "A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation." ;
rdfs:subClassOf obo:CL_0000767 .
obo:REO_0000557 a rdfs:Class ;
rdfs:label "amino acid reagent" ;
rdfs:comment "an organic small molecule reagent that is a carboxylic acid containing one or more amino groups, or an chemical analog engineered to mimic such an amino acid" ;
rdfs:subClassOf obo:REO_0000446 .
obo:NCBITaxon_57975 a rdfs:Class ;
rdfs:label "Burkholderia thailandensis" ;
rdfs:subClassOf obo:NCBITaxon_32008 .
obo:CL_0001003 a rdfs:Class ;
rdfs:label "mature CD8_alpha-negative CD11b-positive dendritic cell" ;
rdfs:comment "Mature CD8_alpha-negative CD11b-positive dendritic cell is a CD8_alpha-negative CD11b-positive dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive." ;
rdfs:subClassOf obo:CL_0000999 .
obo:NCBITaxon_8364 a rdfs:Class ;
rdfs:label "Xenopus (Silurana) tropicalis" ;
rdfs:subClassOf obo:NCBITaxon_8342 .
obo:REO_0000000 a rdfs:Class ;
rdfs:label "reagent"@en ;
rdfs:comment "a material entity that bears a reagent role, such that it is intended to be applied in a scientific technique to participate in a chemical interaction facilitating the generation of knowledge about some distinct entity, or the generation of some distinct material specified output" ;
rdfs:subClassOf obo:OBI_0000047 , .
obo:MOD_00696 a rdfs:Class ;
rdfs:label "phosphorylated residue" ;
rdfs:comment "A protein modification that effectively replaces a hydrogen atom with a phosphono group (H2PO3 or 'phosphate')." ;
rdfs:subClassOf obo:PR_000025513 .
obo:OBI_0000070 a rdfs:Class ;
rdfs:label "assay"@en ;
rdfs:comment "A planned process with the objective to produce information about some evaluant"@en ;
rdfs:subClassOf obo:REO_0000075 .
obo:NCBITaxon_11234 a rdfs:Class ;
rdfs:label "Measles virus" ;
rdfs:subClassOf obo:NCBITaxon_11158 .
obo:CL_0000795 a rdfs:Class ;
rdfs:label "CD8-positive, alpha-beta regulatory T cell" ;
rdfs:comment "A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release." ;
rdfs:subClassOf obo:CL_0000815 .
obo:SO_1000046 a rdfs:Class ;
rdfs:label "pericentric_inversion" ;
rdfs:comment "A chromosomal inversion that includes the centromere." ;
rdfs:subClassOf obo:SO_1000030 .
obo:CL_0002077 a rdfs:Class ;
rdfs:label "ecto-epithelial cell" ;
rdfs:comment "An epithelial cell derived from ectoderm." ;
rdfs:subClassOf obo:CL_0000066 .
obo:CHEBI_17562 a rdfs:Class ;
rdfs:label "cytidine" ;
rdfs:comment "A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:CHEBI_29075 a rdfs:Class ;
rdfs:label "mononucleotide" ;
rdfs:subClassOf obo:CHEBI_36976 .
obo:SO_1000031 a rdfs:Class ;
rdfs:label "interchromosomal_mutation" ;
rdfs:comment "A chromosomal structure variation whereby more than one chromosome is involved." ;
rdfs:subClassOf obo:SO_1000183 .
obo:IAO_0000402 a rdfs:Class ;
rdfs:label "two dimensional cartesian spatial coordinate datum"@en ;
rdfs:comment "A cartesion spatial coordinate datum that uses two values to specify a position within a two dimensional spatial region"@en ;
rdfs:subClassOf obo:IAO_0000400 .
obo:OBI_0000275 a rdfs:Class ;
rdfs:label "analyte role"@en ;
rdfs:comment "Analyte role is a role borne by a molecular entity and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role"@en ;
rdfs:subClassOf obo:REO_0000248 .
obo:MOD_00047 a rdfs:Class ;
rdfs:label "O-phospho-L-threonine" ;
rdfs:comment "A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine." ;
rdfs:subClassOf obo:MOD_00696 .
obo:CL_0000741 a rdfs:Class ;
rdfs:label "spinal accessory motor neuron" ;
rdfs:comment "A motor neuron that is located in the cervical region of the spinal cord and selectively innervates the sternocleidmastoid or trapezius muscle. Unlike other motor neurons, they extend axons dorsally along lateral margins of the spinal cord." ;
rdfs:subClassOf obo:CL_0000100 .
obo:SO_0000453 a rdfs:Class ;
rdfs:label "chromosomal_transposition" ;
rdfs:comment "A chromosome structure variant whereby a region of a chromosome has been transferred to another position. Among interchromosomal rearrangements, the term transposition is reserved for that class in which the telomeres of the chromosomes involved are coupled (that is to say, form the two ends of a single DNA molecule) as in wild-type." ;
rdfs:subClassOf obo:SO_1000183 .
obo:CHEBI_37978 a rdfs:Class ;
rdfs:label "silicon-32 atom" ;
rdfs:comment "The radioactive isotope of silicon with relative atomic mass 31.974148. The longest-lived silicon radionuclide with half-life of 172 years." ;
rdfs:subClassOf obo:CHEBI_27573 .
obo:NCBITaxon_9545 a rdfs:Class ;
rdfs:label "Macaca nemestrina" ;
rdfs:subClassOf obo:NCBITaxon_9539 .
obo:REO_0000462 a rdfs:Class ;
rdfs:label "obsolete_bioactive organic small molecule" ;
rdfs:subClassOf .
obo:REO_0000538 a rdfs:Class ;
rdfs:label "obsolete_non-polar polarity" ;
rdfs:comment "A molecular quality that inheres in a molecular entity by virtue of the bearer not exhibiting sufficient separation of electric charge such that it does not exhibit an electric dipole moment." ;
rdfs:subClassOf obo:REO_0000537 .
obo:NCBITaxon_10090 a rdfs:Class ;
rdfs:label "Mus musculus" ;
rdfs:subClassOf obo:NCBITaxon_10088 .
obo:REO_0000024 a rdfs:Class ;
rdfs:label "adeno-associated virus shuttle plasmid" ;
rdfs:comment "A viral plasmid carrying sequence elements that allow for packaging of genetic cargo into baculoviral capsids for expression in target cells. Adeno-associated viral expression systems can be used with non-dividing cells, and cargo DNA has the ability to stably integrate into the host cell genome at a specific site (designated AAVS1) in the human chromosome 19." ;
rdfs:subClassOf obo:REO_0000023 .
obo:CL_0000619 a rdfs:Class ;
rdfs:label "support cell (sensu Nematoda)" ;
rdfs:subClassOf obo:CL_0000124 .
obo:REO_0000988 a rdfs:Class ;
rdfs:label "genomic sequence feature" ;
rdfs:comment "a sequence feature that represents an extent of nucleic acid sequence (zero or greater) from the genome of some cell or virion" ;
rdfs:subClassOf obo:SO_0000110 .
obo:REO_0000612 a rdfs:Class ;
rdfs:label "IgD immunoglobulin complex, circulating" ;
rdfs:subClassOf obo:GO_0042571 .
obo:CL_0001010 a rdfs:Class ;
rdfs:label "mature dermal dendritic cell" ;
rdfs:comment "Mature dermal dendritic cell is a dermal dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive." ;
rdfs:subClassOf obo:CL_0001006 .
obo:IAO_0000577 a rdfs:Class ;
rdfs:label "CRID symbol"@en ;
rdfs:comment "A symbol that is part_of a CRID and that is sufficient to look up a record from the CRID's registry."@en ;
rdfs:subClassOf obo:IAO_0000028 .
obo:REO_0000309 a rdfs:Class ;
rdfs:label "obsolete_reagent role 2" ;
rdfs:comment """v4 def (newest, 12-10-11):
a role inhering in a material entity that is (1) intended to be input into some scientific technique to facilitate the generation of data about some other entity, or the production of a material output that does not derive from the bearer of the reagent role unless the output is itself a reagent, and (2) comprised (only) of molecular-scale parts intended to participate in a chemical reaction or interaction during this technique
Note that if we say a reagent now consists only of the components of a material intended to participate in some reaction . . . we may now be able to say that a reagent is:
a role inhereing in a molecular entity (single or multi-chain entiteis or mixtures), or in the combined molecular parts of some larger material entity, that are intended to participate in a chemical reaction or interaction as part of a scientific technique to generate data about some other entity, or produce some material output that does not derive from the bearer unless the output is itself a reagent.
This last part assures that things like dNTPs and P32 incorporated into an oligo probe bear reagent roles, as they are not used on their own in a reagent capacity, but rather are always incorported into some other molecular entity which has a reagent role. So this means that ANY input into a material processing technique with a reagent creation objective (be it an incorporant or non-incorporant) realizes a reagent role in this process? Or is the reagent role of dNTPs realized only when the reagent role of the resulting PCR product (ie probe, construct/insert etc) is realized? Same goes for construct inserts - are these reagents?
So may say something like : \". . . and realized in a scientific technique whereby the bearer (or a larger reagent of which it is a part) . . . \"""" ;
rdfs:subClassOf .
obo:REO_0000375 a rdfs:Class ;
rdfs:label "cell selection technique" ;
rdfs:comment "a material processing technique in which a subset of cells is separated from some total population of input cells, based on a specified attribute or set of attributes they bear " ;
rdfs:subClassOf obo:REO_0000159 , obo:REO_0000378 .
obo:NCBITaxon_94988 a rdfs:Class ;
rdfs:label "Lethenteron" ;
rdfs:subClassOf obo:NCBITaxon_7746 .
obo:CHEBI_36937 a rdfs:Class ;
rdfs:label "nitrogen-17 atom" ;
rdfs:subClassOf obo:CHEBI_25555 .
obo:CL_0000534 a rdfs:Class ;
rdfs:label "primary interneuron" ;
rdfs:subClassOf obo:CL_0000530 .
obo:OBI_0600043 a rdfs:Class ;
rdfs:label "genetic transformation"@en ;
rdfs:comment "the introduction. alteration or integration of genetic material into a cell or organism"@en ;
rdfs:subClassOf .
obo:CL_0002448 a rdfs:Class ;
rdfs:label "Ly49H-negative natural killer cell" ;
rdfs:comment "A NK1.1-positive T cell that is Ly49H-negative." ;
rdfs:subClassOf obo:CL_0002438 .
obo:REO_0000216 a rdfs:Class ;
rdfs:label "obsolete_specimen" ;
rdfs:comment "a 'specimen' is considered as a single instance of a class of entities, and unlike a 'sample', is not necessarily considered as representative of some larger population" ;
rdfs:subClassOf .
obo:CL_0002109 a rdfs:Class ;
rdfs:label "B220-positive CD38-positive naive B cell" ;
rdfs:comment "A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery." ;
rdfs:subClassOf obo:CL_0002101 .
obo:CL_0000673 a rdfs:Class ;
rdfs:label "Kenyon cell" ;
rdfs:subClassOf obo:CL_0000117 .
obo:CL_0000998 a rdfs:Class ;
rdfs:label "CD8_alpha-negative CD11b-negative dendritic cell" ;
rdfs:comment "CD8_alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8_alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells." ;
rdfs:subClassOf obo:CL_0000990 .
obo:REO_0000451 a rdfs:Class ;
rdfs:label "obsolete_group" ;
rdfs:comment "A defined linked collection of atoms or a single atom within a molecular entity" ;
rdfs:subClassOf obo:REO_0000449 .
obo:CL_0002171 a rdfs:Class ;
rdfs:label "globose cell of olfactory epithelium" ;
rdfs:comment "A rounded or elliptical epithelial cell, with pale-staining open face nucleus and pale cytoplasm rich in free ribosomes and clusters of centrioles; form a distinct basal zone spaced slightly from the basal surface of the epithelium." ;
rdfs:subClassOf obo:CL_0002169 .
obo:CL_0002344 a rdfs:Class ;
rdfs:label "CD56-negative, CD161-positive immature natural killer cell" ;
rdfs:comment "A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive." ;
rdfs:subClassOf obo:CL_0000823 .
obo:REO_0000527 a rdfs:Class ;
rdfs:label "experimentally modified multicellular organsim cell in vitro" ;
rdfs:comment "an experimentally modified multicellular organism cell that is not part of some organism, but rather is part of a controlled artificial environment for use in some investigation." ;
rdfs:subClassOf obo:CL_0000578 , obo:REO_0000371 , obo:REO_0000373 .
obo:CL_0000101 a rdfs:Class ;
rdfs:label "sensory neuron" ;
rdfs:comment "Any neuron having a sensory function; an afferent neuron conveying sensory impulses." ;
rdfs:subClassOf obo:CL_0000526 .
obo:REO_0000436 a rdfs:Class ;
rdfs:label "obsolete_polynucleotide" ;
rdfs:comment "molecule is a biopolymer composed of 13 or more nucleotide monomers covalently bonded in a chain" ;
rdfs:subClassOf .
obo:REO_0000277 a rdfs:Class ;
rdfs:label "fluorescent stain" ;
rdfs:subClassOf obo:REO_0000218 .
obo:CHEBI_25608 a rdfs:Class ;
rdfs:label "nucleoside phosphate" ;
rdfs:comment "a nucleoside-containing small molecule that contains at least one phosphate group bound to its sugar ring" ;
rdfs:subClassOf obo:REO_0000803 .
obo:SO_0001742 a rdfs:Class ;
rdfs:label "copy_number_gain" ;
rdfs:comment "A sequence alteration whereby the copy number of a given regions is greater than the reference sequence." ;
rdfs:subClassOf obo:SO_0001019 .
obo:CL_0002252 a rdfs:Class ;
rdfs:label "epithelial cell of esophagus" ;
rdfs:comment "An epithelial cell of the esophagus." ;
rdfs:subClassOf obo:CL_0002251 .
obo:CL_0002371 a rdfs:Class ;
rdfs:label "somatic cell" ;
rdfs:comment "A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell)." ;
rdfs:subClassOf obo:REO_0000520 .
obo:SO_0001026 a rdfs:Class ;
rdfs:label "genome" ;
rdfs:comment "A genome is the sum of genetic material within a cell or virion." ;
rdfs:subClassOf obo:SO_0001260 .
obo:CL_0002008 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-positive eosinophil progenitor cell" ;
rdfs:comment "A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell." ;
rdfs:subClassOf obo:CL_0000611 .
obo:UBERON_0007222 a rdfs:Class ;
rdfs:label "late adult stage" ;
rdfs:subClassOf obo:UBERON_0000113 .
obo:REO_0000685 a rdfs:Class ;
rdfs:label "synthetic oligopeptide" ;
rdfs:comment "a synthetic polypeptide of relatively low molecular weight, typically consisting of 50 or fewer amino acid residues" ;
rdfs:subClassOf obo:OBI_0100065 .
obo:CL_0000354 a rdfs:Class ;
rdfs:label "blastemal cell" ;
rdfs:subClassOf obo:CL_0000048 .
obo:UO_0000095 a rdfs:Class ;
rdfs:label "volume unit" ;
rdfs:comment "A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas." ;
rdfs:subClassOf obo:REO_0000707 .
obo:CL_0000614 a rdfs:Class ;
rdfs:label "basophilic myelocyte" ;
rdfs:comment "A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive." ;
rdfs:subClassOf obo:CL_0000768 .
obo:CARO_0000040 a rdfs:Class ;
rdfs:label "acellular anatomical structure" ;
rdfs:comment "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." ;
rdfs:subClassOf obo:CARO_0000003 .
obo:REO_0000152 a rdfs:Class ;
rdfs:label "targeting construct"@en ;
rdfs:comment "a DNA construct that is able to take part in homologous recombination in a host with the intent of introducing site specific genomic modifications." ;
rdfs:subClassOf obo:REO_0000007 .
obo:MOD_00783 a rdfs:Class ;
rdfs:label "dimethylated L-arginine" ;
rdfs:comment "A protein modification that effectively replaces two hydrogen atoms of an L-arginine residue with two methyl groups." ;
rdfs:subClassOf obo:MOD_00427 .
obo:CL_0000886 a rdfs:Class ;
rdfs:label "nasal and broncial associated lymphoid tissue macrophage" ;
rdfs:comment "A mucosa-associated lymphoid tissue macrophage found in the nasal and bronchial mucosa-associated lymphoid tissues." ;
rdfs:subClassOf obo:CL_0000884 .
obo:CHEBI_37102 a rdfs:Class ;
rdfs:label "nucleoside pentaphosphate" ;
rdfs:subClassOf obo:CHEBI_25608 .
obo:CL_0000784 a rdfs:Class ;
rdfs:label "plasmacytoid dendritic cell" ;
rdfs:comment "A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection." ;
rdfs:subClassOf obo:CL_0000451 .
obo:CHEBI_37975 a rdfs:Class ;
rdfs:label "silicon-28 atom" ;
rdfs:comment "The stable isotope of silicon with relative atomic mass 27.9769265. The most abundant (92.23 atom percent) isotope of naturally occurring silicon." ;
rdfs:subClassOf obo:CHEBI_27573 .
obo:CL_0000662 a rdfs:Class ;
rdfs:label "neuroglioblast (sensu Nematoda)" ;
rdfs:subClassOf obo:CL_0000468 .
obo:CL_0000897 a rdfs:Class ;
rdfs:label "CD4-positive, alpha-beta memory T cell" ;
rdfs:comment "CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122- high." ;
rdfs:subClassOf obo:CL_0000813 .
obo:REO_0000757 a rdfs:Class ;
rdfs:label "genomic library" ;
rdfs:comment "A DNA construct library comprised of constructs that carry insert DNA fragments covering the entire genome of a source organism. " ;
rdfs:subClassOf obo:REO_0000748 .
obo:CHEBI_33521 a rdfs:Class ;
rdfs:label "metal atom" ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:MOD_00703 a rdfs:Class ;
rdfs:label "isoprenylated residue" ;
rdfs:comment "A protein modification that effectively replaces a hydrogen atom with a group derived from an isoprene polymer, such as a geranyl (C10), farnesyl (C15) or geranylgeranyl (C20) group." ;
rdfs:subClassOf obo:PR_000025513 .
obo:SO_1000157 a rdfs:Class ;
rdfs:label "uninverted_interchromosomal_transposition" ;
rdfs:comment "An interchromosomal transition where the segment between the first two breaks listed is removed and inserted at the third break; the insertion is in cytologically the same orientation as its flanking segments." ;
rdfs:subClassOf obo:SO_1000155 .
obo:CHEBI_49696 a rdfs:Class ;
rdfs:label "krypton atom" ;
rdfs:comment "A noble gas atom that has formula Kr." ;
rdfs:subClassOf obo:CHEBI_33309 .
obo:CL_0002083 a rdfs:Class ;
rdfs:label "type I cell of adrenal medulla" ;
rdfs:comment "A chromaffin cell of the adrenal medulla that produces norepinephrine." ;
rdfs:subClassOf obo:CL_0000336 .
obo:CL_0000583 a rdfs:Class ;
rdfs:label "alveolar macrophage" ;
rdfs:comment "A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative." ;
rdfs:subClassOf obo:CL_0000864 .
obo:NCBITaxon_162425 a rdfs:Class ;
rdfs:label "Emericella nidulans" ;
rdfs:subClassOf obo:NCBITaxon_4751 .
obo:CL_0002263 a rdfs:Class ;
rdfs:label "transitional cell of parathyroid gland" ;
rdfs:comment "One of three types of epithelial cells that populate the parathyroid gland; cytological characteristics intermediate between those of the chief cell and of the oxyphil cell. Because only one hormone is produced, the three cell forms are widely believed to be different phases in the life cycle of a single cell type, with the chief cell being its physiologically active stage." ;
rdfs:subClassOf obo:CL_0002260 .
obo:CL_0002430 a rdfs:Class ;
rdfs:label "CD4-intermediate, CD8-positive double-positive thymocyte" ;
rdfs:comment "A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor." ;
rdfs:subClassOf obo:CL_0000809 .
obo:CHEBI_33704 a rdfs:Class ;
rdfs:label "alpha-amino acid" ;
rdfs:subClassOf .
obo:CL_0000705 a rdfs:Class ;
rdfs:label "R6 photoreceptor cell" ;
rdfs:subClassOf obo:CL_0000488 .
obo:CL_0000754 a rdfs:Class ;
rdfs:label "type 2 cone bipolar cell (sensu Mus)" ;
rdfs:comment "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is not well filled and the dendrites are more delicate than in type 1 cells. The axon terminal is bushier and exhibits a dense plexus of varicosities in the inner part of sublamina 1." ;
rdfs:subClassOf obo:CL_0000752 .
obo:OBI_0000796 a rdfs:Class ;
rdfs:label "purification objective" ;
rdfs:comment "The objective to separate a material entity into different compositions of which one or more have are purified fractions that contain higher concentration of a desired component, while others contain impurities and are not of interest" ;
rdfs:subClassOf obo:OBI_0000681 .
obo:CL_0002347 a rdfs:Class ;
rdfs:label "CD27-high, CD11b-high natural killer cell" ;
rdfs:comment "A mature natural killer cell that is CD27-high and CD11b-high. This cell type is capable of interferon-gamma secretion." ;
rdfs:subClassOf obo:CL_0002426 .
obo:REO_0000386 a rdfs:Class ;
rdfs:label "unmodified unicellular organism ex environment" ;
rdfs:comment "an unmodified unicellular organism that is not part of a natural environment, but instead part of some controlled artificial environment for use in some investigation." ;
rdfs:subClassOf obo:REO_0000522 , obo:REO_0000530 .
obo:SO_1000020 a rdfs:Class ;
rdfs:label "C_to_G_transversion" ;
rdfs:subClassOf obo:SO_1000018 .
obo:CL_0002188 a rdfs:Class ;
rdfs:label "glomerular endothelial cell" ;
rdfs:comment "An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate." ;
rdfs:subClassOf obo:CL_0000666 .
obo:NCBITaxon_9534 a rdfs:Class ;
rdfs:label "Chlorocebus aethiops" ;
rdfs:subClassOf obo:NCBITaxon_9443 .
obo:CL_0000359 a rdfs:Class ;
rdfs:label "vascular associated smooth muscle cell" ;
rdfs:comment "A smooth muscle cell assocatiated with the vasculature." ;
rdfs:subClassOf obo:CL_0000192 .
obo:IAO_0000316 a rdfs:Class ;
rdfs:label "introduction to a publication about an investigation"@en ;
rdfs:comment "A part of a publication about an investigation that is about the objective specification (why the investigation is being done)"@en ;
rdfs:subClassOf obo:IAO_0000314 .
obo:REO_0000138 a rdfs:Class ;
rdfs:label "cellular morphology"@en ;
rdfs:comment "a morphology quality that describes the appearance of a cell" ;
rdfs:subClassOf obo:PATO_0000051 , obo:PATO_0001396 .
obo:REO_0000859 a rdfs:Class ;
rdfs:label "person" ;
rdfs:subClassOf obo:NCBITaxon_9606 , obo:REO_0000230 .
obo:UBERON_0000112 a rdfs:Class ;
rdfs:label "juvenile stage" ;
rdfs:comment "The stage of being a sexually immature adult animal." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:OBI_0000747 a rdfs:Class ;
rdfs:label "material sample" ;
rdfs:comment "A material entity that has the material sample role" ;
rdfs:subClassOf obo:OBI_0000047 , obo:OBI_0100051 , .
obo:NCBITaxon_31033 a rdfs:Class ;
rdfs:label "Takifugu rubripes" ;
rdfs:subClassOf obo:NCBITaxon_32443 .
obo:CL_0000116 a rdfs:Class ;
rdfs:label "pioneer neuron" ;
rdfs:comment "Pioneer neurons establish a pathway in the developing central nervous system and then undergo programmed cell death once the adult axons, which follow them, have made connections with the target site. Thus, they are a transient cell type involved in axon guidance." ;
rdfs:subClassOf obo:CL_0000540 .
obo:CL_0000545 a rdfs:Class ;
rdfs:label "T-helper 1 cell" ;
rdfs:comment "A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma." ;
rdfs:subClassOf obo:CL_0000492 .
obo:CARO_0000019 a rdfs:Class ;
rdfs:label "compound organ component" ;
rdfs:comment "Multi-tissue structure that is part of a compound organ." ;
rdfs:subClassOf obo:CARO_0000055 .
obo:CL_0002069 a rdfs:Class ;
rdfs:label "type II vestibular sensory cell" ;
rdfs:comment "Mostly cylindrical, resemble Type 1 in their contents and the presence of a kinocilium and stereocilium apically; much greater variation in size, some almost span the entire thickness of the sensory epithelium, while others are smaller than Type 1; receive multiple efferent nerve boutons around their bases as well as afferent endings, which are small expansions rather than chalices." ;
rdfs:subClassOf obo:CL_0000609 .
obo:REO_0000416 a rdfs:Class ;
rdfs:label "obsolete_non-information organic molecular entity" ;
rdfs:subClassOf .
obo:REO_0000570 a rdfs:Class ;
rdfs:label "obsolete_polar solvent reagent" ;
rdfs:comment "a polar solvent that bears a reagent role" ;
rdfs:subClassOf .
obo:OBI_1110094 a rdfs:Class ;
rdfs:label "immunization"@en ;
rdfs:comment "The process of an epitope that is part of or derived from an immunogen coming into contact with adaptive immune cells resulting in these cells acquiring immune effector functions specific for the epitope."@en ;
rdfs:subClassOf obo:GO_0008150 .
obo:NCBITaxon_7088 a rdfs:Class ;
rdfs:label "Lepidoptera" ;
rdfs:subClassOf obo:NCBITaxon_50557 .
obo:REO_0000768 a rdfs:Class ;
rdfs:label "oligonucleotide library" ;
rdfs:comment "A nucleic acid library that is a collection of nucleic acid molecules, stored in pools containing a single species of nucleic acid." ;
rdfs:subClassOf obo:REO_0000123 .
obo:OBI_0200031 a rdfs:Class ;
rdfs:label "differential expression analysis objective"@en ;
rdfs:comment "A differential expression analysis objective is a data transformation objective whose input consists of expression levels of entities (such as transcripts or proteins), or of sets of such expression levels, under two or more conditions and whose output reflects which of these are likely to have different expression across such conditions."@en ;
rdfs:subClassOf obo:OBI_0200166 .
obo:CHEBI_37981 a rdfs:Class ;
rdfs:label "sulfur-34 atom" ;
rdfs:comment "The stable isotope of sulfur with relative atomic mass 33.9678668 and 4.21 atom percent natural abundance." ;
rdfs:subClassOf obo:CHEBI_26833 .
obo:CL_0001019 a rdfs:Class ;
rdfs:label "CD115-positive monocyte OR common dendritic progenitor" ;
rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1111000)(PMID: 19243617)." ;
rdfs:subClassOf obo:CL_0002031 .
obo:CL_0002177 a rdfs:Class ;
rdfs:label "folliculostellate cell of pars distalis of adenohypophysis" ;
rdfs:comment "A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature." ;
rdfs:subClassOf obo:CL_0000710 .
obo:CL_0000803 a rdfs:Class ;
rdfs:label "CD4-negative CD8-negative gamma-delta intraepithelial T cell" ;
rdfs:comment "A gamma-delta intraepithelial T cell that has the phenotype CD4-negative and CD8-negative." ;
rdfs:subClassOf obo:CL_0000801 .
obo:REO_0000595 a rdfs:Class ;
rdfs:label "obsolete_epitope" ;
rdfs:subClassOf .
obo:CL_0000570 a rdfs:Class ;
rdfs:label "parafollicular cell" ;
rdfs:comment "A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. Expresses a form of the neural cell adhesion molecule (N-CAM) on their surface. Secrets calcitonin, 5-hydroxytryptamine and dopamine." ;
rdfs:subClassOf obo:CL_0000710 .
obo:UBERON_0000071 a rdfs:Class ;
rdfs:label "death stage" ;
rdfs:comment "End of the life of an organism." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:NCBITaxon_3041 a rdfs:Class ;
rdfs:label "Chlorophyta" ;
rdfs:subClassOf obo:NCBITaxon_131567 .
obo:CL_0002314 a rdfs:Class ;
rdfs:label "external supporting cell of vestibular epithelium" ;
rdfs:comment "An auditory epithelial support cell located in the vestibular epithelium that has many hallmarks of glial cells. This cell type express glial markers such as vimentin, S100, glutamate-aspartate transporter, low affinity neurotrophin receptor p75, glial fibrillary acidic protein, and proteolipid protein." ;
rdfs:subClassOf obo:CL_0002316 .
obo:CL_0000000 a rdfs:Class ;
rdfs:label "cell" ;
rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
rdfs:subClassOf .
obo:GO_0002250 a rdfs:Class ;
rdfs:label "adaptive immune response" ;
rdfs:comment "An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory)." ;
rdfs:subClassOf obo:GO_0006955 .
obo:CL_0000755 a rdfs:Class ;
rdfs:label "type 3 cone bipolar cell (sensu Mus)" ;
rdfs:comment "An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is delicate and the dendritic tips appear small when compared with type 1 cells. The axon terminal is stratified and restricted to sublamina 2 of the inner plexiform layer." ;
rdfs:subClassOf obo:CL_0000752 .
obo:CL_0002149 a rdfs:Class ;
rdfs:label "epithelial cell of uterus" ;
rdfs:comment "An epithelial cell of the uterus." ;
rdfs:subClassOf obo:CL_0002076 .
obo:CL_0000546 a rdfs:Class ;
rdfs:label "T-helper 2 cell" ;
rdfs:comment "A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4." ;
rdfs:subClassOf obo:CL_0000492 .
obo:CL_0000864 a rdfs:Class ;
rdfs:label "tissue-resident macrophage" ;
rdfs:comment "A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." ;
rdfs:subClassOf obo:CL_0000235 .
obo:CL_0000350 a rdfs:Class ;
rdfs:label "amnioserosal cell" ;
rdfs:subClassOf obo:CL_0000349 .
obo:SO_1000146 a rdfs:Class ;
rdfs:label "complex_chromosomal_mutation" ;
rdfs:comment "A chromosome structure variant with 4 or more breakpoints." ;
rdfs:subClassOf obo:SO_1000183 .
obo:CL_0002182 a rdfs:Class ;
rdfs:label "surface mucosal cell of stomach" ;
rdfs:comment "A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall." ;
rdfs:subClassOf obo:CL_0002180 .
obo:CL_0001008 a rdfs:Class ;
rdfs:label "Kit and Sca1-positive hematopoietic stem cell" ;
rdfs:comment "A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative." ;
rdfs:subClassOf obo:CL_0000037 .
obo:IAO_0000309 a rdfs:Class ;
rdfs:label "diagram"@en ;
rdfs:comment "A figure that expresses one or more propositions"@en ;
rdfs:subClassOf obo:IAO_0000308 .
obo:CHEBI_29999 a rdfs:Class ;
rdfs:label "L-serine residue" ;
rdfs:subClassOf obo:CHEBI_33700 .
obo:REO_0000425 a rdfs:Class ;
rdfs:label "DNA primer reagent" ;
rdfs:comment "a DNA oligonucleotide reagent that is applied in a technique (typically PCR) to bind to some complementary nucleic acid template and serve as a starting point for nucleic acid synthesis" ;
rdfs:subClassOf obo:REO_0000033 , obo:REO_0000424 , obo:REO_0000514 .
obo:CL_0002235 a rdfs:Class ;
rdfs:label "luminal cell of prostatic acinus" ;
rdfs:comment "A cell of the luminal layer of the epithelium in the prostatic acinus." ;
rdfs:subClassOf obo:CL_0002340 .
obo:CL_0000127 a rdfs:Class ;
rdfs:label "astrocyte" ;
rdfs:comment "A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury." ;
rdfs:subClassOf obo:CL_0000126 .
obo:OBI_0000785 a rdfs:Class ;
rdfs:label "controlled variable specification"@en ;
rdfs:comment "Controlled variable specification is a part of a study design. They are the entities that could vary, but are kept constant to prevent their influence on the effect of the independent variable on the dependent."@en ;
rdfs:subClassOf obo:IAO_0000033 .
obo:REO_0000112 a rdfs:Class ;
rdfs:label "PC12 HD-Q74"@en ;
rdfs:comment "a stable inducible rat phaeochromocytoma (PC12) cell line expressing GFP-tagged exon 1 of the huntingtin gene with 74 glutamine repeats, driven by a doxycycline-dependent Tet-On promoter. This cell line can be used for in vitro studies to evaluate compounds to treat Huntingtonās disease." ;
rdfs:subClassOf obo:REO_0000116 , obo:REO_0000119 , obo:REO_0000120 .
obo:CL_0000206 a rdfs:Class ;
rdfs:label "chemoreceptor cell" ;
rdfs:comment "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood." ;
rdfs:subClassOf obo:CL_0000006 .
obo:REO_0000179 a rdfs:Class ;
rdfs:label "obsolete_analyte labeling technique"@en ;
rdfs:comment "a technique that attaches or incorporates some molecular label into a molecular entity intended to serve as an analyte in some assay" ;
rdfs:subClassOf .
obo:CL_0002394 a rdfs:Class ;
rdfs:label "CD141-positive myeloid dendritic cell" ;
rdfs:comment "A myeloid dendritic cell found in the blood, lymph nodes, tonsil, bone marrow, and spleen that is CD141-positive (BDCA-3), XCR1-positive, and Clec9A-positive. This cell-type can cross-present antigen to CD8-positive T cells and can produce inteferon-beta." ;
rdfs:subClassOf obo:CL_0000784 .
obo:IAO_0000100 a rdfs:Class ;
rdfs:label "data set"@en ;
rdfs:comment "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ;
rdfs:subClassOf obo:IAO_0000027 .
obo:REO_0000786 a rdfs:Class ;
rdfs:label "obsolete_material transfer function" ;
rdfs:comment "a function to to deliver some 'material to be combined' to a new location within or attached to some 'target of material combination'" ;
rdfs:subClassOf .
obo:REO_0000957 a rdfs:Class ;
rdfs:label "material genome" ;
rdfs:comment "a material entity that represents all genetic material in a cell or virion. The material genome is typically molecular aggregate of all the chromosomal DNA and epi-chromosomal DNA that represents all sequences that are heritable by progeny of a cell or virion." ;
rdfs:subClassOf .
obo:NCBITaxon_10114 a rdfs:Class ;
rdfs:label "Rattus" ;
rdfs:subClassOf obo:NCBITaxon_9989 .
obo:UBERON_0004707 a rdfs:Class ;
rdfs:label "pharyngula stage" ;
rdfs:comment "A stage that follows the blastula, gastrula and neurula stages. At the pharyngula stage, all vertebrate embryos show remarkable similarities." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:REO_0000296 a rdfs:Class ;
rdfs:label "obsolete_creating a mixture of molecules in solution" ;
rdfs:subClassOf .
obo:NCBITaxon_6499 a rdfs:Class ;
rdfs:label "Aplysia" ;
rdfs:subClassOf obo:NCBITaxon_6447 .
obo:REO_0000893 a rdfs:Class ;
rdfs:label "biomolecule antibody target" ;
rdfs:comment "a molecular entity that is biologically-occurring (ie of a type produced or derived from an organism), and is the intended experimental target of some antibody reagent in virtue of its containing as part some molecular antigen" ;
rdfs:subClassOf obo:CHEBI_24431 , obo:REO_0000872 .
obo:CL_0002397 a rdfs:Class ;
rdfs:label "CD14-positive, CD16-positive monocyte" ;
rdfs:comment "An intermediate monocyte that is CD14-positive, CD16-positive." ;
rdfs:subClassOf obo:CL_0002393 .
obo:CL_0000906 a rdfs:Class ;
rdfs:label "activated CD8-positive, alpha-beta T cell" ;
rdfs:comment "A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative." ;
rdfs:subClassOf obo:CL_0000625 .
obo:REO_0000873 a rdfs:Class ;
rdfs:label "obsolete_biologically-based material" ;
rdfs:subClassOf .
obo:REO_0000303 a rdfs:Class ;
rdfs:label "obsolete_contextual re-location objective" ;
rdfs:comment """the objective for a material processing technique to yield a specified output that has undergone a change in context or location, but to which no internal physical changes have been made (ie no material added or removed, and/or structural rearrangements)
Alt: an objective for a material processing technique to yield a specified output that has undergone a change in context or location, but to which no changes have been made affecting its inherent physical structure (ie no material added or removed, and/or structural rearrangements)""" ;
rdfs:subClassOf .
obo:SO_1000041 a rdfs:Class ;
rdfs:label "intrachromosomal_transposition" ;
rdfs:comment "A chromosome structure variation whereby a transposition occurred within a chromosome." ;
rdfs:subClassOf obo:SO_1000038 .
obo:OBI_1110014 a rdfs:Class ;
rdfs:label "epitope binding by adaptive immune receptor"@en ;
rdfs:comment "is the process in which an adaptive immune receptor binds to a material entity (realizing its disposition). The binding affinity is significant enough to trigger an immune response. Specifically, transient non-specific binding of adaptive immune receptors occurring during immune surveillance is not considered significant binding."@en ;
rdfs:subClassOf obo:GO_0008150 , obo:REO_0000257 .
obo:OGMS_0000079 a rdfs:Class ;
rdfs:label "portion of pathological body substance" ;
rdfs:comment "TODO: Define, relate to disorder, and place in the OGMS hierarchy."@en ;
rdfs:subClassOf obo:CARO_0000004 , obo:REO_0000049 .
obo:CL_0000048 a rdfs:Class ;
rdfs:label "multi fate stem cell" ;
rdfs:comment "A stem cell that can give rise to multiple lineages of cells." ;
rdfs:subClassOf obo:CL_0000723 .
obo:CL_0002325 a rdfs:Class ;
rdfs:label "mammary alveolar cell" ;
rdfs:comment "The milk-producing cell of the alveolar unit that emerges during pregnancy." ;
rdfs:subClassOf obo:CL_0002327 .
obo:REO_0000623 a rdfs:Class ;
rdfs:label "IgG2c monoclonal antibody reagent" ;
rdfs:subClassOf obo:REO_0000501 , obo:REO_0000608 .
obo:NCBITaxon_28450 a rdfs:Class ;
rdfs:label "Burkholderia pseudomallei" ;
rdfs:subClassOf obo:NCBITaxon_32008 .
obo:SO_0000800 a rdfs:Class ;
rdfs:label "assortment_derived_duplication" ;
rdfs:comment "A multi-chromosome duplication aberration generated by reassortment of other aberration components." ;
rdfs:subClassOf obo:SO_0001504 .
obo:CHEBI_33700 a rdfs:Class ;
rdfs:label "canonical amino-acid residue" ;
rdfs:subClassOf obo:REO_0000460 .
obo:REO_0000394 a rdfs:Class ;
rdfs:label "selected passaged unicellular organism culture" ;
rdfs:comment "a unicellular organism culture that has been passaged, and is the output of some cell culture cell selection technique whereby a specified subset of cells from an input cell culture is selected based on their exhibiting some desired feature, and propagated as a new cell culture." ;
rdfs:subClassOf obo:REO_0000125 , obo:REO_0000382 , obo:REO_0000405 .
obo:REO_0000529 a rdfs:Class ;
rdfs:label "naturally occurring" ;
rdfs:comment "a quality inhereing in any material entity that is OF A TYPE existing in nature (ie represents a type or structural arrangement that exists without human intent or interventions, although a given bearer does not necessarily need to be produced naturally - see comment)." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:REO_0000389 a rdfs:Class ;
rdfs:label "biomaterial culture maintenance" ;
rdfs:comment "a material processing technique that is the collection of all techniques directly involved in maintenance of biomaterial culture in a metabolically active state (ie maintenance of biological processes typical of the given type of culture)." ;
rdfs:subClassOf obo:REO_0000159 .
obo:REO_0000775 a rdfs:Class ;
rdfs:label "bioinorganic reagent" ;
rdfs:comment "A chemical reagent comprised of 2 or more elements combined in a fixed ratio and containing metal, carbon, and hydrogen atoms." ;
rdfs:subClassOf obo:REO_0000004 , obo:REO_0000771 .
obo:REO_0000968 a rdfs:Class ;
rdfs:label "transgenic organism production" ;
rdfs:comment """a material processing technique with the goal of producing an organism that stably carries some transgenic genetic material (ie encoding sequence from the genome of some other organism).
This can be achieved through:
(1) de novo creation of a transgenic organism - using embryonic stem cells into which genomic sequence alterations have been made through addition of exogneous genes from other organisms. In the case of genetically modified virus, this is achieved through the transfection of plasmids encoding a transgene of interest along with viral coat protein, replication, and packaging genes that encode the machinery necessary to assemble a viral capsid containing the transgene and secrete it from the transfected cells;
or
(2) by modification of an existing organism through the stable introduction of an exogneous trasngene into one or more cells from the organism. """ ;
rdfs:subClassOf obo:REO_0000969 .
obo:CL_0002036 a rdfs:Class ;
rdfs:label "Slamf1-positive multipotent progenitor cell" ;
rdfs:comment "A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive." ;
rdfs:subClassOf obo:CL_0000837 .
obo:REO_0000656 a rdfs:Class ;
rdfs:label "obsolete_portioned material role" ;
rdfs:subClassOf obo:REO_0000651 .
obo:OBI_0000962 a rdfs:Class ;
rdfs:label "training objective" ;
rdfs:comment "An training objective which is fulfilled by the provision of some training" ;
rdfs:subClassOf obo:IAO_0000005 .
obo:CL_0000375 a rdfs:Class ;
rdfs:label "osteoprogenitor cell" ;
rdfs:subClassOf obo:CL_0000035 .
obo:REO_0000035 a rdfs:Class ;
rdfs:label "RNA oligonucleotide" ;
rdfs:comment "a ribonucleic acid molecule consisting of a short, linear single strand of typically 100 or fewer nucleotides" ;
rdfs:subClassOf obo:CHEBI_33697 , obo:REO_0000281 .
obo:PATO_0002187 a rdfs:Class ;
rdfs:label "polar polarity" ;
rdfs:comment "Polar polarity is a quality that inheres in a molecular entity when the molecular entity is polar, i.e. does possess an electric dipole." ;
rdfs:subClassOf obo:PATO_0002186 .
obo:NCBITaxon_8316 a rdfs:Class ;
rdfs:label "Notophthalmus viridescens" ;
rdfs:subClassOf obo:NCBITaxon_8315 .
obo:CL_0000790 a rdfs:Class ;
rdfs:label "immature alpha-beta T cell" ;
rdfs:comment "An alpha-beta T cell that has an immature phenotype and has not completed T cell selection." ;
rdfs:subClassOf obo:CL_0002420 .
obo:CL_0002319 a rdfs:Class ;
rdfs:label "neural cell" ;
rdfs:comment "A cell that is part of the nervous system." ;
rdfs:subClassOf obo:CL_0002371 .
obo:OBI_0302729 a rdfs:Class ;
rdfs:label "chemical solution"@en ;
rdfs:comment "A material entity that is made up of at least 2 scattered molecular aggregates, one playing the role of solvent and the other one playing the role of solute."@en ;
rdfs:subClassOf obo:CHEBI_60004 .
obo:CHEBI_17053 a rdfs:Class ;
rdfs:label "L-aspartic acid" ;
rdfs:comment "The L-enantiomer of aspartic acid." ;
rdfs:subClassOf obo:REO_0000545 .
obo:CL_0000979 a rdfs:Class ;
rdfs:label "IgG memory B cell" ;
rdfs:comment "An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface." ;
rdfs:subClassOf obo:CL_0000972 .
obo:CL_0000037 a rdfs:Class ;
rdfs:label "hematopoietic stem cell" ;
rdfs:comment "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." ;
rdfs:subClassOf obo:CL_0000988 .
obo:CL_0002015 a rdfs:Class ;
rdfs:label "Kit-negative, Ly-76 high polychromatophilic erythroblast" ;
rdfs:comment "A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative." ;
rdfs:subClassOf obo:CL_0000550 .
obo:OBI_0200173 a rdfs:Class ;
rdfs:label "background correction objective"@en ;
rdfs:comment "A background correction objective is a data transformation objective where the aim is to remove irrelevant contributions from the measured signal, e.g. those due to instrument noise or sample preparation."@en ;
rdfs:subClassOf obo:OBI_0200168 .
obo:NCBITaxon_37176 a rdfs:Class ;
rdfs:label "Ovibos moschatus" ;
rdfs:subClassOf obo:NCBITaxon_40674 .
obo:REO_0000202 a rdfs:Class ;
rdfs:label "investigation objective" ;
rdfs:subClassOf obo:IAO_0000005 .
obo:CL_0002134 a rdfs:Class ;
rdfs:label "stromal cell of ovarian medulla" ;
rdfs:comment "A stromal cell of the ovarian medulla." ;
rdfs:subClassOf obo:CL_0002132 .
obo:IAO_0000572 a rdfs:Class ;
rdfs:label "documenting"@en ;
rdfs:comment "a planned process in which a document is created or added to by including the specified input in it."@en ;
rdfs:subClassOf obo:OBI_0000011 .
obo:CHEBI_49637 a rdfs:Class ;
rdfs:label "hydrogen atom" ;
rdfs:comment "A s-block element atom that has formula H." ;
rdfs:subClassOf obo:CHEBI_25585 .
obo:REO_0000105 a rdfs:Class ;
rdfs:label "mutant cell line"@en ;
rdfs:comment "a multicellular organism cell culture with an established genetic alteration in a specific gene of interest. This mutation is typiclly made to alter the activity of this target gene in order to study its function." ;
rdfs:subClassOf obo:REO_0000156 .
obo:REO_0000581 a rdfs:Class ;
rdfs:label "obsolete_adaptive immune response" ;
rdfs:subClassOf .
obo:CL_0000322 a rdfs:Class ;
rdfs:label "pneumocyte" ;
rdfs:comment "An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates." ;
rdfs:subClassOf obo:CL_0002368 .
obo:NCBITaxon_633 a rdfs:Class ;
rdfs:label "Yersinia pseudotuberculosis" ;
rdfs:subClassOf obo:NCBITaxon_2 .
obo:CL_0002174 a rdfs:Class ;
rdfs:label "follicular cell of ovary" ;
rdfs:comment "A cell within the follicle of an ovary." ;
rdfs:subClassOf obo:CL_0002078 .
obo:CL_0000499 a rdfs:Class ;
rdfs:label "stromal cell" ;
rdfs:comment "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere." ;
rdfs:subClassOf obo:CL_0002320 .
a rdfs:Class ;
rdfs:label "generically_dependent_continuant" ;
rdfs:comment "Definition: A continuant [snap:Continuant] that is dependent on one or other independent continuant [snap:IndependentContinuant] bearers. For every instance of A requires some instance of (an independent continuant [snap:IndependentContinuant] type) B but which instance of B serves can change from time to time." ;
rdfs:subClassOf .
obo:SO_1000017 a rdfs:Class ;
rdfs:label "transversion" ;
rdfs:comment "Change of a pyrimidine nucleotide, C or T, into a purine nucleotide, A or G, or vice versa." ;
rdfs:subClassOf obo:SO_0001483 .
obo:DOID_1289 a rdfs:Class ;
rdfs:label "neurodegenerative disease" ;
rdfs:comment "A central nervous system disease that results_in the progressive deterioration of tissue or organ function or structure, whether due to normal bodily wear or lifestyle choices." ;
rdfs:subClassOf obo:DOID_331 .
obo:CL_0002055 a rdfs:Class ;
rdfs:label "CD38-negative immature B cell" ;
rdfs:comment "An immature B cell that is CD38-negative, CD10-low, CD21-low, and CD22-high." ;
rdfs:subClassOf obo:CL_0000816 .
obo:ERO_0001189 a rdfs:Class ;
rdfs:label "transgenic baculovirus" ;
rdfs:comment "A transgenic virus derived from a baculovirus that is engineered to serve as a vehicle to carry foreign genetic material, which it can transfer into cells or organisms." ;
rdfs:subClassOf obo:ERO_0001188 .
obo:CL_0000437 a rdfs:Class ;
rdfs:label "gonadtroph" ;
rdfs:comment "A rounded cell that is usually situated next to sinusoids; secretes follicular stimulating hormone (FSH) and luteinizing hormone (LH)." ;
rdfs:subClassOf obo:CL_0000639 .
obo:MOD_00394 a rdfs:Class ;
rdfs:label "acetylated residue" ;
rdfs:comment "A protein modification that effectively replaces a hydrogen atom with an acetyl group." ;
rdfs:subClassOf obo:PR_000025513 .
obo:REO_0000271 a rdfs:Class ;
rdfs:label "radiolabeled DNA probe" ;
rdfs:comment "a DNA probe that contains at least one atom that is a radioactive isotope, such as P-32 or P-33, that emits a radioactive signal to allow detection of the probe and target DNA with which it hybridizes" ;
rdfs:subClassOf obo:REO_0000270 , obo:REO_0000289 .
obo:CL_0000743 a rdfs:Class ;
rdfs:label "hypertrophic chondrocyte" ;
rdfs:comment "Chondrocyte that is terminally differentiated, produces type X collagen, is large in size, and often associated with the replacement of cartilage by bone (endochondral ossification)." ;
rdfs:subClassOf obo:CL_0000138 .
obo:REO_0000682 a rdfs:Class ;
rdfs:label "engineered" ;
rdfs:comment "a quality inhering in a material whose structural composition is at least partially designed or engineered by some intentional agent, and produced as part of some planned process" ;
rdfs:subClassOf obo:PATO_0001241 .
obo:CL_0002058 a rdfs:Class ;
rdfs:label "Gr1-low non-classical monocyte" ;
rdfs:comment "A resident monocyte that is Gr-1 low, CD43-positive, and CX3CR1-positive." ;
rdfs:subClassOf obo:CL_0001022 .
obo:GO_0008150 a rdfs:Class ;
rdfs:label "biological_process" ;
rdfs:comment "Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." .
obo:CL_0002210 a rdfs:Class ;
rdfs:label "red muscle cell" ;
rdfs:comment "A slow muscle cell that contains high levels of myoglobin and oxygen storing proteins giving the cell a red appearance." ;
rdfs:subClassOf obo:CL_0000188 .
obo:CL_0002104 a rdfs:Class ;
rdfs:label "IgG-negative double negative memory B cell" ;
rdfs:comment "An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative." ;
rdfs:subClassOf obo:CL_0000981 .
obo:CL_0002192 a rdfs:Class ;
rdfs:label "metamyelocyte" ;
rdfs:comment "A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare." ;
rdfs:subClassOf obo:CL_0002191 .
obo:CL_0000917 a rdfs:Class ;
rdfs:label "Tc1 cell" ;
rdfs:comment "A CD8-positive, alpha-beta positive T cell expressing T-bet and eomesodermin and secreting interferon-gamma." ;
rdfs:subClassOf obo:CL_0000908 .
obo:CHEBI_28659 a rdfs:Class ;
rdfs:label "phosphorus atom" ;
rdfs:comment "A pnictogen that has formula P." ;
rdfs:subClassOf obo:CHEBI_25585 .
obo:REO_0000382 a rdfs:Class ;
rdfs:label "passaged unicellular organism culture" ;
rdfs:comment "a unicellular cell culture that has been passaged" ;
rdfs:subClassOf obo:REO_0000125 , obo:REO_0000404 .
obo:CHEBI_16977 a rdfs:Class ;
rdfs:label "L-alanine" ;
rdfs:comment "The L-enantiomer of alanine." ;
rdfs:subClassOf obo:REO_0000545 .
obo:OBI_0000639 a rdfs:Class ;
rdfs:label "material separation objective" ;
rdfs:comment "is an objective to transform a material entity into spatially separated components." ;
rdfs:subClassOf obo:OBI_0000456 .
obo:REO_0000604 a rdfs:Class ;
rdfs:label "IgG immunoglobulin complex, circulating" ;
rdfs:subClassOf obo:GO_0042571 .
obo:REO_0000422 a rdfs:Class ;
rdfs:label "obsolete_organic large molecule chemical reagent" ;
rdfs:comment "An organic macromolecule that bears a reagent role " ;
rdfs:subClassOf .
obo:OBI_0000838 a rdfs:Class ;
rdfs:label "material maintenance" ;
rdfs:comment "a process with that achieves the objective to maintain some or all of the characteristics of an input material over time" ;
rdfs:subClassOf obo:OBI_0000011 .
obo:CL_0000397 a rdfs:Class ;
rdfs:label "ganglion interneuron" ;
rdfs:subClassOf obo:CL_0000099 .
obo:REO_0000342 a rdfs:Class ;
rdfs:label "microarray DNA probe" ;
rdfs:comment "a DNA oligonucleotide that is immobilized on the surface of a microarray support substrate, to sequester and allow for the quantification of complementary target oligonucleotides from some nucleic acid sample under investigation" ;
rdfs:subClassOf obo:REO_0000269 , obo:REO_0000852 .
obo:UBERON_0000105 a rdfs:Class ;
rdfs:label "life cycle stage" ;
rdfs:comment "A spatiotemporal region encompassing some part of the life cycle of an organism." ;
rdfs:subClassOf .
obo:UBERON_0007233 a rdfs:Class ;
rdfs:label "4 cell stage" ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:NCBITaxon_1282 a rdfs:Class ;
rdfs:label "Staphylococcus epidermidis" ;
rdfs:subClassOf obo:NCBITaxon_1279 .
obo:REO_0000123 a rdfs:Class ;
rdfs:label "nucleic acid library"@en ;
rdfs:comment "a reagent library comprised of a pools of different nucleic acid molecules, each pool being a uniform collection of one type of molecule. The individual nucleic acid members of such libraries are often stored as cloned in DNA constructs that are propagated in host micro-organisms such as bacteria, yeast, or virus." ;
rdfs:subClassOf obo:REO_0000725 .
obo:CL_0000788 a rdfs:Class ;
rdfs:label "naive B cell" ;
rdfs:comment "A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD27-negative and that has not yet been activated by antigen in the periphery." ;
rdfs:subClassOf obo:CL_0000785 .
obo:PATO_0001536 a rdfs:Class ;
rdfs:label "solubility" ;
rdfs:comment "A molecular quality that inheres in a molecular entity by virtue of the bearer's disposition to dissolve in a liquid." ;
rdfs:subClassOf obo:PATO_0002182 .
obo:CL_0002111 a rdfs:Class ;
rdfs:label "CD38-negative unswitched memory B cell" ;
rdfs:comment "An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative." ;
rdfs:subClassOf obo:CL_0000970 .
obo:REO_0000371 a rdfs:Class ;
rdfs:label "multicellular organism cell" ;
rdfs:comment "a cell that is part of or derives from a multicellular organism" ;
rdfs:subClassOf obo:CL_0000000 .
a rdfs:Class ;
rdfs:label "entity" .
obo:REO_0000984 a rdfs:Class ;
rdfs:label "selectable marker gene" ;
rdfs:comment "a gene is encoded in soem genetic element that encodes some product whose presence or abundance is detected, directly or indirectly, in order to determine is some specified experimental modification has occurred successfully" ;
rdfs:subClassOf obo:SO_0000704 .
obo:CL_0002047 a rdfs:Class ;
rdfs:label "Fraction B precursor B cell" ;
rdfs:comment "A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative." ;
rdfs:subClassOf obo:CL_0002400 .
obo:REO_0000056 a rdfs:Class ;
rdfs:label "endothelial morphology"@en ;
rdfs:subClassOf obo:REO_0000138 .
obo:NCBITaxon_7004 a rdfs:Class ;
rdfs:label "Locusta migratoria" ;
rdfs:subClassOf obo:NCBITaxon_6993 .
obo:CL_0002163 a rdfs:Class ;
rdfs:label "internal pillar cell of cochlea" ;
rdfs:comment "A rod-shpaed cell that forms a single row adjacent to and supporting the inner hair cells." ;
rdfs:subClassOf obo:CL_1000191 .
obo:CL_0000448 a rdfs:Class ;
rdfs:label "white fat cell" ;
rdfs:comment "Fat cells with light coloration and few mitochondria. They contain a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole." ;
rdfs:subClassOf obo:CL_0000136 .
obo:REO_0000082 a rdfs:Class ;
rdfs:label "yeast two hybrid screening" ;
rdfs:comment "A technique used to discover protein-protein interactions and protein-DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively." ;
rdfs:subClassOf obo:OBI_0000070 , obo:REO_0000161 .
obo:CL_0002033 a rdfs:Class ;
rdfs:label "short term hematopoietic stem cell" ;
rdfs:comment "A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Spa-1-positive, CD34-positive, CD150-positive, and is Flt3-negative." ;
rdfs:subClassOf obo:CL_0001008 .
obo:IAO_0000131 a rdfs:Class ;
rdfs:label "serial number"@en ;
rdfs:comment "A serial number is an information content entity which is a unique sequence of characters borne by part of manufactured product or its packaging that is assigned to each individual in some class of products, and so can serve as a way to identify an individual product within the class. Serial numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
rdfs:subClassOf obo:IAO_0000028 .
obo:CL_0002152 a rdfs:Class ;
rdfs:label "columnar cell of endocervix" ;
rdfs:comment "A columnar cell of the cervix uteri." ;
rdfs:subClassOf obo:CL_0002149 .
obo:CL_0002073 a rdfs:Class ;
rdfs:label "transitional myocyte" ;
rdfs:comment "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes." ;
rdfs:subClassOf obo:CL_0002086 .
obo:CL_0000625 a rdfs:Class ;
rdfs:label "CD8-positive, alpha-beta T cell" ;
rdfs:comment "A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor." ;
rdfs:subClassOf obo:CL_0000791 .
obo:NCBITaxon_539 a rdfs:Class ;
rdfs:label "Eikenella corrodens" ;
rdfs:subClassOf obo:NCBITaxon_2 .
obo:GO_0031050 a rdfs:Class ;
rdfs:label "dsRNA fragmentation" ;
rdfs:comment "Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CL_0000242 a rdfs:Class ;
rdfs:label "Merkel cell" ;
rdfs:comment "A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute. Merkel cells are closely associated with an expanded terminal bulb of an afferent myelinated nerve fiber." ;
rdfs:subClassOf obo:CL_0000312 .
obo:CL_0000530 a rdfs:Class ;
rdfs:label "primary neuron" ;
rdfs:subClassOf obo:CL_0000540 .
obo:CL_0000752 a rdfs:Class ;
rdfs:label "cone retinal bipolar cell" ;
rdfs:comment "A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer." ;
rdfs:subClassOf obo:CL_0000748 .
obo:CL_0002004 a rdfs:Class ;
rdfs:label "CD34-negative, GlyA-negative proerythroblast" ;
rdfs:comment "A proerythoblast that is CD34-negative and GlyA-negative." ;
rdfs:subClassOf obo:CL_0000547 .
obo:CL_0000072 a rdfs:Class ;
rdfs:label "non-branched duct epithelial cell" ;
rdfs:subClassOf obo:CL_0000068 .
obo:REO_0000681 a rdfs:Class ;
rdfs:label "obsolete_material genetic sequence bearer" ;
rdfs:comment "a material_entity in which a concretization of some genetic sequence region inheres" ;
rdfs:subClassOf .
obo:REO_0000861 a rdfs:Class ;
rdfs:label "laboratory" ;
rdfs:comment "An organizational unit (as opposed to the physical facility) that performs research, provides services, or processes materials" ;
rdfs:subClassOf obo:OBI_0000245 .
obo:CL_0002123 a rdfs:Class ;
rdfs:label "B220-low CD38-positive IgG-negative class switched memory B cell" ;
rdfs:comment "A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive." ;
rdfs:subClassOf obo:CL_0002119 .
obo:OBI_0000383 a rdfs:Class ;
rdfs:label "transfer function"@en ;
rdfs:comment "A transfer function is a function to displace a material from one location to another."@en ;
rdfs:subClassOf .
obo:REO_0000331 a rdfs:Class ;
rdfs:label "indicator reagent role" ;
rdfs:comment "a reagent role inihering in a molecular entity that is intended to be detected in an assay as a proxy to yield information about some analyte or evaluant of interest" ;
rdfs:subClassOf obo:REO_0000001 .
obo:REO_0000898 a rdfs:Class ;
rdfs:label "lipid group" ;
rdfs:comment "an organic chemical group that consists of some lipid moiety derived from a lipid molecular entity. here we consider only lipids of biological origin." ;
rdfs:subClassOf obo:CHEBI_33247 , obo:REO_0000900 .
obo:OBI_0000131 a rdfs:Class ;
rdfs:label "molecular feature identification objective"@en ;
rdfs:comment "Molecular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features of a biological system, e.g. expression profiling, copy number of molecular components, epigenetic modifications."@en ;
rdfs:subClassOf obo:OBI_0000015 .
obo:OBI_0000751 a rdfs:Class ;
rdfs:label "dependent variable specification"@en ;
rdfs:comment "dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies."@en ;
rdfs:subClassOf obo:IAO_0000033 .
obo:NCBITaxon_10141 a rdfs:Class ;
rdfs:label "Cavia porcellus" ;
rdfs:subClassOf obo:NCBITaxon_9989 .
obo:NCBITaxon_11646 a rdfs:Class ;
rdfs:label "Lentivirus" ;
rdfs:subClassOf obo:NCBITaxon_11632 .
obo:CL_0000557 a rdfs:Class ;
rdfs:label "granulocyte monocyte progenitor cell" ;
rdfs:comment "A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata-1, Gata2 but do express C/EBPa, and Pu.1." ;
rdfs:subClassOf obo:CL_0002032 .
obo:CL_0000969 a rdfs:Class ;
rdfs:label "regulatory B cell" ;
rdfs:comment "A mature B cell that has the phenotype CD1d-positive and expresses interleukin-10. This cell type has been associated with suppression of chronic inflammatory responses and T cell responses." ;
rdfs:subClassOf obo:CL_0000785 .
obo:REO_0000977 a rdfs:Class ;
rdfs:label "natural organic small molecule" ;
rdfs:comment "an organic small molecule that is 'natural', in that it exhibits a structure that is found in nature. Such molecules can be produced naturally or through some directed chemical synthesis or engineering technique." ;
rdfs:subClassOf obo:REO_0000445 .
obo:ERO_0000004 a rdfs:Class ;
rdfs:label "instrument" ;
rdfs:comment "Material entity that is designed to have a function and play a role in scientific investigation." ;
rdfs:subClassOf obo:OBI_0000047 , .
obo:CL_0000575 a rdfs:Class ;
rdfs:label "corneal epithelial cell" ;
rdfs:comment "An epithelial cell of the cornea." ;
rdfs:subClassOf obo:CL_0002159 .
obo:OBI_0600014 a rdfs:Class ;
rdfs:label "material component separation"@en ;
rdfs:comment "a material processing in which components of an input material become segregated in space"@en ;
rdfs:subClassOf obo:REO_0000159 .
obo:CL_0002190 a rdfs:Class ;
rdfs:label "squamous cell of epidermis" ;
rdfs:comment "A flat keratinocyte immediately below the cornified layer." ;
rdfs:subClassOf obo:CL_0000312 .
obo:REO_0000281 a rdfs:Class ;
rdfs:label "oligonucleotide" ;
rdfs:comment "a nucleic acid polymer consisting of a short, linear, single strand of typically 100 or fewer nucleotides" ;
rdfs:subClassOf obo:CHEBI_33696 .
obo:CL_0000489 a rdfs:Class ;
rdfs:label "scotopic photoreceptor cell" ;
rdfs:subClassOf obo:CL_0000210 .
obo:REO_0000562 a rdfs:Class ;
rdfs:label "information macromolecule" ;
rdfs:comment "This class represents natural or artificial polymers that carry sequence information of a genetic nature (ie, information that is translatable to a nucleic acid or protein sequence in some defined way). This includes sequence information naturally part of or encoded by the genomes of organisms, as well as artificially designed and synthesized nucleic acid or polypeptide modleules, and nucleic acid/protein 'analogs', whose sequences map to genetic information carried in natural nucleic acids and proteins." ;
rdfs:subClassOf obo:REO_0000461 .
obo:REO_0000241 a rdfs:Class ;
rdfs:label "obsolete_facilitator role" ;
rdfs:comment "a research material role inhering in a material entiity and realized by the bearer's specified input into some assay or material processing technique, such that : (1) in the case of an assay, the bearer is not the evaluant about which data is generated, but rather facililtates the generation of such data; and (2) in the case of a material processing technique, the bearer does not contribute 'significant' material to the specified output material, but rather facilitates conditions necessary for the generation of this output material." ;
rdfs:subClassOf obo:REO_0000982 .
obo:REO_0000781 a rdfs:Class ;
rdfs:label "phage display peptide library" ;
rdfs:comment "A peptide library that contains phage display, an expression system of peptides, at the surface of phage particles. The construction of a phage display library is accomplished by the incorporation of the nucleotide sequence encoding the peptide to be displayed into a phage genome as a fusion to a gene encoding a phage coat protein. The fusion of the protein with the phage coat protein ensures that the peptide to be displayed is presented at the surface of the mature phage, while the sequence encoding it is contained within the same phage particle, allowing a physical link between the phenotype and genotype of the expressed peptide." ;
rdfs:subClassOf obo:REO_0000777 .
obo:CL_0002044 a rdfs:Class ;
rdfs:label "Kit-positive, integrin beta7-high basophil mast progenitor cell" ;
rdfs:comment "A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive FcRgammaII/III-positive and Sca1-negative." ;
rdfs:subClassOf obo:CL_0002028 .
obo:CL_0002336 a rdfs:Class ;
rdfs:label "buccal mucosa cell" ;
rdfs:comment "An endothelial cell that lines the oral cavitiy including the mucosa of the gums, the palate, the lip, and the cheek." ;
rdfs:subClassOf obo:CL_0002261 .
obo:NCBITaxon_345480 a rdfs:Class ;
rdfs:label "Acrobeloides ellesmerensis" ;
rdfs:subClassOf obo:NCBITaxon_6231 .
obo:SO_0001255 a rdfs:Class ;
rdfs:label "autopolyploid" ;
rdfs:comment "A polyploid where the multiple chromosome set was derived from the same organism." ;
rdfs:subClassOf obo:SO_0001254 .
obo:MOD_00128 a rdfs:Class ;
rdfs:label "N6-pyridoxal phosphate-L-lysine" ;
rdfs:comment "A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine." ;
rdfs:subClassOf obo:PR_000025513 .
obo:CL_0000105 a rdfs:Class ;
rdfs:label "pseudounipolar neuron" ;
rdfs:comment "Neuron with two neurites that are fused grossly when they protrude from the soma and bifurcate a short distance from the soma." ;
rdfs:subClassOf obo:CL_0000540 .
obo:REO_0000850 a rdfs:Class ;
rdfs:label "modified amino acid reagent" ;
rdfs:comment "an amino acid reagent representing a modified version of some amino acid (i.e. is functionally derived from some other amino acid)" ;
rdfs:subClassOf obo:CHEBI_25359 , obo:REO_0000577 .
obo:CL_0002160 a rdfs:Class ;
rdfs:label "basal external epithelial cell of tympanic membrane" ;
rdfs:comment "A cell type found in the basal epithelial layer on the external side of the tympanic membrane. Cell type is flattened with intracellular spaces of variable dimensions." ;
rdfs:subClassOf obo:CL_0002158 .
obo:NCBITaxon_485 a rdfs:Class ;
rdfs:label "Neisseria gonorrhoeae" ;
rdfs:subClassOf obo:NCBITaxon_2 .
obo:CL_0000928 a rdfs:Class ;
rdfs:label "activated CD4-negative, CD8-negative type I NK T cell" ;
rdfs:comment "A type I NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has phenotype CD4-negative, CD8-negative, CD69-positive, and downregulated NK markers." ;
rdfs:subClassOf obo:CL_0000924 .
obo:UO_0000051 a rdfs:Class ;
rdfs:label "concentration unit" ;
rdfs:comment "A unit which represents a standard measurement of how much of a given substance there is mixed with another substance." ;
rdfs:subClassOf obo:REO_0000707 .
obo:IAO_0000180 a rdfs:Class ;
rdfs:label "heatmap"@en ;
rdfs:subClassOf obo:IAO_0000038 .
obo:REO_0000609 a rdfs:Class ;
rdfs:label "IgG3 immunoglobulin complex, circulating" ;
rdfs:subClassOf obo:GO_0042571 .
obo:OBI_0200005 a rdfs:Class ;
rdfs:label "feature extraction objective"@en ;
rdfs:comment "A feature extraction objective is a data transformation objective where the aim of the data transformation is to generate quantified values from a scanned image."@en ;
rdfs:subClassOf obo:OBI_0200166 .
obo:REO_0000447 a rdfs:Class ;
rdfs:label "RNA primer reagent" ;
rdfs:comment "an RNA oligonucleotide reagent that is applied in a technique (typically PCR) to bind to some complementary nucleic acid template and serve as a starting point for nucleic acid synthesiss." ;
rdfs:subClassOf obo:REO_0000044 , obo:REO_0000426 , obo:REO_0000514 .
obo:OBI_0000471 a rdfs:Class ;
rdfs:label "study design execution" ;
rdfs:comment "a planned process that realizes the concretization of a study design" ;
rdfs:subClassOf obo:OBI_0000011 .
obo:REO_0000812 a rdfs:Class ;
rdfs:label "TTP reagent" ;
rdfs:subClassOf obo:CHEBI_63550 , obo:REO_0000457 .
obo:CL_0000828 a rdfs:Class ;
rdfs:label "thromboblast" ;
rdfs:comment "A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates." ;
rdfs:subClassOf obo:CL_0000839 .
obo:CL_0002207 a rdfs:Class ;
rdfs:label "brush cell of trachea" ;
rdfs:comment "Brush cell of the epithelium in the trachea." ;
rdfs:subClassOf obo:CL_0002075 .
obo:IAO_0000330 a rdfs:Class ;
rdfs:label "copyright section"@en ;
rdfs:comment "A document part that describes legal restrictions on making or distributing copies of the document"@en ;
rdfs:subClassOf obo:IAO_0000314 .
obo:NCBITaxon_7159 a rdfs:Class ;
rdfs:label "Aedes aegypti" ;
rdfs:subClassOf obo:NCBITaxon_7157 .
obo:CARO_0000012 a rdfs:Class ;
rdfs:label "multi-cellular organism" ;
rdfs:comment "Anatomical structure that is an individual member of a species and consists of more than one cell." ;
rdfs:subClassOf obo:NCBITaxon_131567 , obo:OBI_0100026 .
obo:REO_0000007 a rdfs:Class ;
rdfs:label "DNA construct" ;
rdfs:comment "A double-stranded DNA molecule capable of autonomous replication, used as a vehicle to transfer foreign genetic material into a host cell. Constructs can be engineered to carry inserts of DNA from external sources, for purposes of cloning and propagation or gene expression in host cells." ;
rdfs:subClassOf obo:CHEBI_4705 , obo:REO_0000030 .
obo:REO_0000674 a rdfs:Class ;
rdfs:label "test class 1" ;
rdfs:subClassOf .
obo:CL_0000777 a rdfs:Class ;
rdfs:label "mesangial phagocyte" ;
rdfs:comment "A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling." ;
rdfs:subClassOf obo:CL_0000864 .
obo:CL_0000658 a rdfs:Class ;
rdfs:label "cuticle secreting cell" ;
rdfs:comment "An epithelial cell that secretes cuticle." ;
rdfs:subClassOf obo:CL_0000327 .
obo:NCBITaxon_746128 a rdfs:Class ;
rdfs:label "Aspergillus fumigatus" ;
rdfs:subClassOf obo:NCBITaxon_5052 .
obo:CL_0000709 a rdfs:Class ;
rdfs:label "R8 photoreceptor cell" ;
rdfs:subClassOf obo:CL_0000488 .
obo:CHEBI_16039 a rdfs:Class ;
rdfs:label "ITP" ;
rdfs:comment "The inosine phosphate that has a triphosphate group at the 5'-position." ;
rdfs:subClassOf obo:CHEBI_17972 .
obo:REO_0000551 a rdfs:Class ;
rdfs:label "unnatural" ;
rdfs:comment "of a type not existing in nature" ;
rdfs:subClassOf obo:PATO_0001241 .
obo:REO_0000282 a rdfs:Class ;
rdfs:label "targeted reporter" ;
rdfs:comment "a molecular reporter that is capable of autonomous, non-covalent association with a molecular target" ;
rdfs:subClassOf obo:REO_0000323 , obo:REO_0000921 .
obo:OBI_0000704 a rdfs:Class ;
rdfs:label "decision tree induction objective" ;
rdfs:comment "A decision tree induction objective is a data transformation objective in which a tree-like graph of edges and nodes is created and from which the selection of each branch requires that some type of logical decision is made." ;
rdfs:subClassOf obo:OBI_0200166 .
obo:REO_0000163 a rdfs:Class ;
rdfs:label "embryonic cell line"@en ;
rdfs:comment "an immortal cell line that derives from cells isolated from an organism during its embryonic life cycle stage" ;
rdfs:subClassOf obo:CLO_0000019 .
obo:NCBITaxon_75939 a rdfs:Class ;
rdfs:label "Dallia pectoralis" ;
rdfs:subClassOf obo:NCBITaxon_32443 .
obo:CL_0000889 a rdfs:Class ;
rdfs:label "myeloid suppressor cell" ;
rdfs:comment "An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive." ;
rdfs:subClassOf obo:CL_0000766 .
obo:REO_0000015 a rdfs:Class ;
rdfs:label "miRNA plasmid" ;
rdfs:comment "An RNA interference plasmid that expresses a short sequence of RNA that includes elements required for processing by endogenous microRNA processing machinery into active microRNA molecules. " ;
rdfs:subClassOf obo:REO_0000013 .
obo:CL_0002350 a rdfs:Class ;
rdfs:label "endocardial cell" ;
rdfs:comment "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin." ;
rdfs:subClassOf obo:CL_0000115 .
obo:SO_1000171 a rdfs:Class ;
rdfs:label "deficient_inversion" ;
rdfs:comment "A chromosomal deletion whereby three breaks occur in the same chromosome; one central region is lost, and the other is inverted." ;
rdfs:subClassOf obo:SO_1000030 .
obo:CL_0000083 a rdfs:Class ;
rdfs:label "epithelial cell of pancreas" ;
rdfs:comment "An epithelial cell of the pancreas." ;
rdfs:subClassOf obo:CL_0000066 .
obo:CL_0002231 a rdfs:Class ;
rdfs:label "epithelial cell of prostate" ;
rdfs:comment "An epithelial cell of the prostate." ;
rdfs:subClassOf obo:CL_0002076 .
obo:CL_0000552 a rdfs:Class ;
rdfs:label "orthochromatic erythroblast" ;
rdfs:comment "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated." ;
rdfs:subClassOf obo:CL_0000765 .
obo:CHEBI_15422 a rdfs:Class ;
rdfs:label "ATP" ;
rdfs:comment "A purine ribonucleoside 5'-triphosphate that has formula C10H16N5O13P3." ;
rdfs:subClassOf obo:CHEBI_17972 .
obo:CHEBI_30218 a rdfs:Class ;
rdfs:label "helium-3 atom" ;
rdfs:comment "The stable isotope of helium with relative atomic mass 3.016029. The least abundant (0.000137 atom percent) isotope of naturally occurring helium." ;
rdfs:subClassOf obo:CHEBI_30217 .
obo:IAO_0000030 a rdfs:Class ;
rdfs:label "information content entity"@en ;
rdfs:comment "an information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity"@en ;
rdfs:subClassOf