PREFIX obo:
PREFIX rdf:
PREFIX rdfs:
PREFIX xsd:
obo:GO_0009268 a rdfs:Class ;
rdfs:label "response to pH" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution." ;
rdfs:subClassOf obo:GO_0009628 .
obo:BFO_0000062 a rdf:Property ;
rdfs:label "preceded_by" ;
rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002086 .
obo:BFO_0000063 a rdf:Property ;
rdfs:label "precedes"@en ;
rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002222 .
obo:BFO_0000066 a rdf:Property ;
rdfs:label "occurs in" ;
rdfs:comment "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000004 .
obo:RO_0000057 a rdf:Property ;
rdfs:label "has participant"@en ;
rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 .
obo:RO_0019000 a rdf:Property ;
rdfs:label "regulates characteristic" ;
rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:PATO_0000001 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002233 a rdf:Property ;
rdfs:label "has input"@en ;
rdfs:comment "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0000057 .
obo:RO_0002211 a rdf:Property ;
rdfs:label "regulates" ;
rdfs:comment "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002411 .
obo:RO_0002018 a rdf:Property ;
rdfs:label "has component process" ;
rdfs:comment "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002180 .
obo:RO_0002479 a rdf:Property ;
rdfs:label "has part that occurs in" ;
rdfs:comment "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000004 .
obo:BFO_0000050 a rdf:Property ;
rdfs:label "part of" ;
rdfs:comment "a core relation that holds between a part and its whole"@en ;
rdfs:range obo:BFO_0000003 , obo:BFO_0000004 , obo:BFO_0000020 , , obo:BFO_0000017 , obo:BFO_0000002 , obo:BFO_0000019 ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0002295 a rdf:Property ;
rdfs:label "results in developmental progression of"@en ;
rdfs:comment "p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss)." ;
rdfs:domain obo:GO_0008150 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002324 .
obo:RO_0002501 a rdf:Property ;
rdfs:label "causal relation between processes" ;
rdfs:comment "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002222 a rdf:Property ;
rdfs:label "temporally related to"@en ;
rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 .
obo:RO_0002334 a rdf:Property ;
rdfs:label "regulated by"@en ;
rdfs:comment "inverse of regulates" ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002427 .
obo:CHEBI_33673 a rdfs:Class ;
rdfs:label "zinc group molecular entity" ;
rdfs:subClassOf obo:CHEBI_33676 .
obo:BFO_0000051 a rdf:Property ;
rdfs:label "has part" ;
rdfs:comment "a core relation that holds between a whole and its part"@en ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:GO_0110165 a rdfs:Class ;
rdfs:label "cellular anatomical structure" ;
rdfs:comment "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses." ;
rdfs:subClassOf obo:GO_0005575 .
obo:GO_0061643 a rdfs:Class ;
rdfs:label "chemorepulsion of axon" ;
rdfs:comment "The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue." ;
rdfs:subClassOf obo:GO_0050919 .
obo:GO_0043556 a rdfs:Class ;
rdfs:label "regulation of translation in response to oxidative stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0032055 , obo:GO_0065007 .
obo:RO_0002212 a rdf:Property ;
rdfs:label "negatively regulates" ;
rdfs:comment "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002305 , obo:RO_0002211 .
obo:GO_0002182 a rdfs:Class ;
rdfs:label "cytoplasmic translational elongation" ;
rdfs:comment "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm." ;
rdfs:subClassOf obo:GO_0006414 .
obo:WBPhenotype_0002196 a rdfs:Class ;
rdfs:label "outward rectifying current variant" ;
rdfs:comment "The driving force of the outward flow of ions does not exceed the inward flow for the opposite driving force or is otherwise altered when compared to that measured for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002197 .
obo:GO_0006521 a rdfs:Class ;
rdfs:label "regulation of amino acid metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080090 .
obo:GO_0060627 a rdfs:Class ;
rdfs:label "regulation of vesicle-mediated transport" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0051049 , obo:GO_0065007 .
obo:WBPhenotype_0000946 a rdfs:Class ;
rdfs:label "pharyngeal nervous system development variant" ;
rdfs:comment "Variations in the progression of a set of interacting or interdependent entities forming the pharyngeal nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses." ;
rdfs:subClassOf obo:WBPhenotype_0000623 .
obo:WBPhenotype_0001048 a rdfs:Class ;
rdfs:label "odorant chemosensory response variant" ;
rdfs:comment "Animals exhibit variations in the chemosensory response to volatile organic compounds compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001040 .
obo:GO_0043051 a rdfs:Class ;
rdfs:label "regulation of nematode pharyngeal pumping" ;
rdfs:comment "Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903998 .
obo:WBPhenotype_0001679 a rdfs:Class ;
rdfs:label "multipolar neuron" ;
rdfs:comment "Neurons have more than one process extending from the cell body." ;
rdfs:subClassOf obo:WBPhenotype_0000905 .
obo:WBPhenotype_0001648 a rdfs:Class ;
rdfs:label "no posterior pharynx" ;
rdfs:comment "Embryos fail to generate cells that give rise to the posterior portion of the pharynx. In C. elegans, the MS blastomere- derived pharyngeal cells constitute the posterior portion of the pharynx." ;
rdfs:subClassOf obo:WBPhenotype_0001646 , obo:WBPhenotype_0001647 .
obo:CHEBI_16701 a rdfs:Class ;
rdfs:label "nucleoside 5'-phosphate" ;
rdfs:comment "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-5 of the ribose ring is mono-, di-, tri- or tetra-phosphorylated." ;
rdfs:subClassOf obo:CHEBI_29075 .
obo:RO_0018034 a rdf:Property ;
rdfs:label "is conjugate acid of" ;
rdfs:range .
obo:RO_0018038 a rdf:Property ;
rdfs:label "has functional parent" ;
rdfs:range .
obo:WBPhenotype_0002470 a rdfs:Class ;
rdfs:label "cilia length variant" ;
rdfs:comment "Animals exhibit variations in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000615 .
obo:CL_0000025 a rdfs:Class ;
rdfs:label "egg cell" ;
rdfs:comment "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization." ;
rdfs:subClassOf obo:CL_0000675 .
obo:RO_0002450 a rdf:Property ;
rdfs:label "directly positively regulates activity of" ;
rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.""" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002448 .
obo:RO_0002162 a rdf:Property ;
rdfs:range .
obo:RO_0002449 a rdf:Property ;
rdfs:label "directly negatively regulates activity of" ;
rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.""" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002448 .
obo:RO_0002448 a rdf:Property ;
rdfs:label "directly regulates activity of" ;
rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.
A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.""" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0011002 , obo:RO_0002436 .
obo:RO_0020105 a rdf:Property ;
rdfs:label "is anatomical entity" ;
rdfs:comment "This property only applies to anatomical entities." ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range .
obo:RO_0002254 a rdf:Property ;
rdfs:label "has developmental contribution from"@en ;
rdfs:comment "x has developmental contribution from y iff x has some part z such that z develops from y"@en ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002258 .
obo:RO_0002202 a rdf:Property ;
rdfs:label "develops_from" ;
rdfs:comment "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y" ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002258 , obo:RO_0002254 .
obo:RO_0002566 a rdf:Property ;
rdfs:label "causally influences" ;
rdfs:comment "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002506 .
obo:RO_0000087 a rdf:Property ;
rdfs:label "has role" ;
rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000023 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0002215 a rdf:Property ;
rdfs:label "capable of"@en ;
rdfs:comment "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002216 .
obo:RO_0000085 a rdf:Property ;
rdfs:label "has function"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000034 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0000053 a rdf:Property ;
rdfs:label "has characteristic"@en ;
rdfs:comment "Inverse of characteristic_of"@en ;
rdfs:range obo:BFO_0000020 .
obo:RO_0002595 a rdf:Property ;
rdfs:label "causal relation between material entity and a process" ;
rdfs:comment "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002258 a rdf:Property ;
rdfs:label "developmentally preceded by"@en ;
rdfs:comment "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p" ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002324 .
obo:RO_0000091 a rdf:Property ;
rdfs:label "has disposition"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000016 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0000056 a rdf:Property ;
rdfs:label "participates in"@en ;
rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000003 .
obo:RO_0002434 a rdf:Property ;
rdfs:label "interacts with" ;
rdfs:comment "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 .
obo:RO_0002216 a rdf:Property ;
rdfs:label "capable of part of"@en ;
rdfs:comment "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002500 , obo:RO_0002328 .
obo:RO_0002506 a rdf:Property ;
rdfs:label "causal relation between entities" ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002384 a rdf:Property ;
rdfs:label "has developmental potential involving"@en ;
rdfs:comment "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)."@en ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002324 .
obo:RO_0011002 a rdf:Property ;
rdfs:label "regulates activity of" ;
rdfs:comment "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002566 .
obo:WBPhenotype_0000908 a rdfs:Class ;
rdfs:label "cloacal morphology variant" ;
rdfs:comment "Any variation in the structural appearance of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000598 , obo:WBPhenotype_0000605 .
obo:PATO_0000689 a rdfs:Class ;
rdfs:label "continuous" ;
rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's being uninterrupted in time, sequence, substance, or extent." ;
rdfs:subClassOf obo:PATO_0000057 .
obo:RO_0002573 a rdf:Property ;
rdfs:label "has modifier" ;
rdfs:comment "A relation that holds between an attribute or a qualifier and another attribute." ;
rdfs:domain obo:BFO_0000020 ;
rdfs:range obo:BFO_0000020 .
obo:WBPhenotype_0001600 a rdfs:Class ;
rdfs:label "contraction response to ouabain resistant" ;
rdfs:comment "Animals require increased concentration or longer exposure to ouabain to elicit the rapid muscular contractions seen in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001599 .
obo:CHEBI_26416 a rdfs:Class ;
rdfs:label "pyridine alkaloid" ;
rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_26421 .
obo:WBPhenotype_0001585 a rdfs:Class ;
rdfs:label "asymmetric cell division variant" ;
rdfs:comment "Any variation in a cell's ability to divide asymmetrically to produce two daughter cells with different developmental potentials compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001235 .
obo:WBPhenotype_0002269 a rdfs:Class ;
rdfs:label "oxygen consumption increased" ;
rdfs:comment "Animals exhibit an increased rate of oxygen utilization compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002141 .
obo:GO_0098609 a rdfs:Class ;
rdfs:label "cell-cell adhesion" ;
rdfs:comment "The attachment of one cell to another cell via adhesion molecules." ;
rdfs:subClassOf obo:GO_0007155 .
obo:CHEBI_29360 a rdfs:Class ;
rdfs:label "methanediide" ;
rdfs:subClassOf obo:CHEBI_38222 .
obo:RO_0018033 a rdf:Property ;
rdfs:label "is conjugate base of" ;
rdfs:range .
obo:WBPhenotype_0000535 a rdfs:Class ;
rdfs:label "organism morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000520 .
obo:GO_0007411 a rdfs:Class ;
rdfs:label "axon guidance" ;
rdfs:comment "The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues." ;
rdfs:subClassOf obo:GO_0097485 .
obo:WBPhenotype_0001007 a rdfs:Class ;
rdfs:label "other abnormality early emb" ;
rdfs:comment "Unclassified abnormality in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001100 .
obo:WBPhenotype_0002210 a rdfs:Class ;
rdfs:label "extra rays" ;
rdfs:comment "Animals exhibit an extra number of the finger-like sensory sensilla that project from the tail and embed in the male fan." ;
rdfs:subClassOf obo:WBPhenotype_0000199 .
obo:GO_0044773 a rdfs:Class ;
rdfs:label "mitotic DNA damage checkpoint signaling" ;
rdfs:comment "A signal transduction process involved in mitotic DNA damage checkpoint." ;
rdfs:subClassOf obo:GO_0000077 , obo:GO_0044774 .
obo:WBPhenotype_0002605 a rdfs:Class ;
rdfs:label "dipeptide repeat protein toxicity suppressed"@en ;
rdfs:comment "Normally toxic dipeptide repeat proteins appear to be less toxic to animals, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002604 .
obo:GO_0042176 a rdfs:Class ;
rdfs:label "regulation of protein catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0051246 , obo:GO_0065007 .
obo:GO_1902119 a rdfs:Class ;
rdfs:label "regulation of meiotic spindle elongation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of meiotic spindle elongation." ;
rdfs:subClassOf obo:GO_0032887 , obo:GO_0065007 , obo:GO_2000241 .
obo:WBPhenotype_0001093 a rdfs:Class ;
rdfs:label "intestinal physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the intestine to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000606 .
obo:CHEBI_51689 a rdfs:Class ;
rdfs:label "enone" ;
rdfs:comment "An α,β-unsaturated ketone of general formula R1R2C=CR3‒C(=O)R4 (R4 ≠ H) in which the C=O function is conjugated to a C=C double bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_51721 , obo:CHEBI_78840 .
obo:WBPhenotype_0000078 a rdfs:Class ;
rdfs:label "seam cells stacked" ;
rdfs:comment "The hypodermal cells, which lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, are misplaced such that they are stacked along the dorsal-ventral axis rather than forming a continuous row of adjacent cells ." ;
rdfs:subClassOf obo:WBPhenotype_0000703 .
obo:WBPhenotype_0002130 a rdfs:Class ;
rdfs:label "post mating variant" ;
rdfs:comment "Males exhibit variations of the behaviors observed in control animals that follow the completion of mating." ;
rdfs:subClassOf obo:WBPhenotype_0000648 .
obo:WBPhenotype_0001574 a rdfs:Class ;
rdfs:label "ATP levels variant" ;
rdfs:comment "Animals exhibit variations in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:GO_0090298 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial DNA replication" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090296 , obo:GO_1901859 , obo:GO_2000104 .
obo:WBPhenotype_0000003 a rdfs:Class ;
rdfs:label "obsolete flattened locomotion path" ;
rdfs:comment "OBSOLETE." .
obo:GO_0031116 a rdfs:Class ;
rdfs:label "positive regulation of microtubule polymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." ;
rdfs:subClassOf obo:GO_0031112 , obo:GO_0031113 , obo:GO_0032273 , obo:GO_0065007 , obo:GO_1902905 .
obo:RO_0002213 a rdf:Property ;
rdfs:label "positively regulates" ;
rdfs:comment "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002304 , obo:RO_0002211 .
obo:WBPhenotype_0001615 a rdfs:Class ;
rdfs:label "anticonvulsant resistant" ;
rdfs:comment "Animals fail to respond to the concentration of compounds that act as anticonvulsants that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001614 .
obo:GO_2000624 a rdfs:Class ;
rdfs:label "positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay." ;
rdfs:subClassOf obo:GO_0061014 , obo:GO_0065007 , obo:GO_2000622 .
obo:CHEBI_29202 a rdfs:Class ;
rdfs:label "isocyanic acid" ;
rdfs:comment "A colourless, volatile, poisonous inorganic compound with the formula HNCO; the simplest stable chemical compound that contains carbon, hydrogen, nitrogen, and oxygen, the four most commonly-found elements in organic chemistry and biology." ;
rdfs:subClassOf obo:CHEBI_33405 , obo:CHEBI_64708 .
obo:RO_0018036 a rdf:Property ;
rdfs:label "is tautomer of" ;
rdfs:range .
obo:WBPhenotype_0000840 a rdfs:Class ;
rdfs:label "Z4 hermaphrodite lineage variant" ;
rdfs:comment "Z4 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000837 .
obo:WBPhenotype_0000793 a rdfs:Class ;
rdfs:label "posterior body morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of the anatomy contained in the posterior region, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000072 , obo:WBPhenotype_0000581 .
obo:WBPhenotype_0001278 a rdfs:Class ;
rdfs:label "transgene expression reduced" ;
rdfs:comment "Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000962 .
obo:WBPhenotype_0000721 a rdfs:Class ;
rdfs:label "obsolete level of reporter gene expression variant" ;
rdfs:comment "OBSOLETE." .
obo:GO_0070160 a rdfs:Class ;
rdfs:label "tight junction" ;
rdfs:comment "A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." ;
rdfs:subClassOf obo:GO_0005911 .
obo:WBls_0000005 a rdfs:Class ;
rdfs:label "blastula embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage until the start of gastrulation." ;
rdfs:subClassOf obo:WBls_0000813 .
obo:GO_1905558 a rdfs:Class ;
rdfs:label "negative regulation of mitotic nuclear envelope disassembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0051129 , obo:GO_0065007 , obo:GO_1905557 .
obo:WBPhenotype_0000416 a rdfs:Class ;
rdfs:label "yolk synthesis variant" ;
rdfs:comment "Variations in the generation of the nutrient protein produced by intestinal cells and secreted by them into the pseudocoelom, from which it can be shared with other tissues in the body compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001093 .
obo:WBPhenotype_0000339 a rdfs:Class ;
rdfs:label "transient bloating" ;
rdfs:comment "Worms sporatically appear turgid or swollen as a result of an excess number of eggs being retained in the uterus." ;
rdfs:subClassOf obo:WBPhenotype_0000862 .
obo:GO_0005488 a rdfs:Class ;
rdfs:label "binding" ;
rdfs:comment "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf obo:GO_0003674 .
obo:CHEBI_33554 a rdfs:Class ;
rdfs:label "organosulfonate oxoanion" ;
rdfs:comment "An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:CHEBI_64256 a rdfs:Class ;
rdfs:label "tunicamycin C1" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 14-methylpentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:WBPhenotype_0000895 a rdfs:Class ;
rdfs:label "obsolete spermatocyte germ cell differentiation abnormal" ;
rdfs:comment "OBSOLETE." .
obo:GO_1904951 a rdfs:Class ;
rdfs:label "positive regulation of establishment of protein localization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of establishment of protein localization." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0065007 , obo:GO_0070201 .
obo:GO_0051494 a rdfs:Class ;
rdfs:label "negative regulation of cytoskeleton organization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0051493 , obo:GO_0065007 .
obo:CHEBI_79008 a rdfs:Class ;
rdfs:label "(R)-nicotinium(1+)" ;
rdfs:comment "The conjugate acid of (R)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:RO_0018039 a rdf:Property ;
rdfs:label "is enantiomer of" ;
rdfs:range .
obo:RO_0018040 a rdf:Property ;
rdfs:label "has parent hydride" ;
rdfs:range .
obo:WBPhenotype_0000789 a rdfs:Class ;
rdfs:label "fluoxetine hypersensitive" ;
rdfs:comment "Animals respond to fluoxetine at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001918 .
obo:GO_0007548 a rdfs:Class ;
rdfs:label "sex differentiation" ;
rdfs:comment "The establishment of the sex of an organism by physical differentiation." ;
rdfs:subClassOf obo:GO_0003006 .
obo:CHEBI_51373 a rdfs:Class ;
rdfs:label "GABA agonist" ;
rdfs:comment "A drug that binds to and activates γ-aminobutyric acid receptors." ;
rdfs:subClassOf obo:CHEBI_51374 .
obo:GO_1905268 a rdfs:Class ;
rdfs:label "negative regulation of chromatin organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1902275 .
obo:CHEBI_38215 a rdfs:Class ;
rdfs:label "calcium channel blocker" ;
rdfs:comment "One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools." ;
rdfs:subClassOf obo:CHEBI_38808 , obo:CHEBI_48706 .
obo:GO_0045764 a rdfs:Class ;
rdfs:label "positive regulation of amino acid metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." ;
rdfs:subClassOf obo:GO_0006521 , obo:GO_0009893 , obo:GO_0065007 .
obo:GO_0051174 a rdfs:Class ;
rdfs:label "regulation of phosphorus metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_1901161 a rdfs:Class ;
rdfs:label "primary amino compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of primary amino compound." ;
rdfs:subClassOf obo:GO_0009056 .
obo:CHEBI_63046 a rdfs:Class ;
rdfs:label "emulsifier" ;
rdfs:comment "The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:CHEBI_33318 a rdfs:Class ;
rdfs:label "main group element atom" ;
rdfs:comment "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:WBbt_0006795 a rdfs:Class ;
rdfs:label "proctodeum" ;
rdfs:comment "Essensially a modified rectum, junction between the alimentary and genital tracts in the male." ;
rdfs:subClassOf obo:WBbt_0005757 , obo:WBbt_0005773 .
obo:BFO_0000034 a rdfs:Class ;
rdfs:label "function"@en ;
rdfs:subClassOf obo:BFO_0000016 .
obo:RO_0000079 a rdf:Property ;
rdfs:label "function of"@en ;
rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000034 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:WBPhenotype_0002431 a rdfs:Class ;
rdfs:label "alternative lengthening of telomeres" ;
rdfs:comment "A telomerase-independent telomere maintenance pathway that allows for strains to survive in the absence of telomerase." ;
rdfs:subClassOf obo:WBPhenotype_0000879 .
obo:WBPhenotype_0000922 a rdfs:Class ;
rdfs:label "male longitudinal muscle development variant" ;
rdfs:comment "Any variation in the progression of somatic (striated) muscles that run longitudinally in males over time from its initial formation to its mature form compared to control. In C. elegans males have 3 additional sets of sex-specific longitudinal muscles (anterior and posterior outer, anterior and posterior inner, and caudal) that contribute to the body wall musculature (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000860 , obo:WBPhenotype_0000921 , obo:WBPhenotype_0000930 .
obo:WBbt_0005760 a rdfs:Class ;
rdfs:label "somatic nervous system" ;
rdfs:comment "Part of the nervous system that lies completely outside the pharynx." ;
rdfs:subClassOf obo:WBbt_0005746 .
obo:WBPhenotype_0002156 a rdfs:Class ;
rdfs:label "temperature learning variant" ;
rdfs:comment "Wild-type animals will exhibit an altered temperature preference based on food/temperature conditioning. Temperature learning variants do not exhibit altered responses to temperature after conditioning compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001780 .
obo:GO_0098657 a rdfs:Class ;
rdfs:label "import into cell" ;
rdfs:comment "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." ;
rdfs:subClassOf obo:GO_0006810 .
obo:WBPhenotype_0001047 a rdfs:Class ;
rdfs:label "aqueous positive chemotaxis variant" ;
rdfs:comment "Animals exhibit variations in the movement towards typically attractive water-soluble chemicals compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000635 , obo:WBPhenotype_0001443 .
obo:GO_1903748 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to mitochondrion" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitochondrion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903747 , obo:GO_1903828 .
obo:CHEBI_64255 a rdfs:Class ;
rdfs:label "tunicamycin B3" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 13-methyltetradecanoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:CHEBI_50905 a rdfs:Class ;
rdfs:label "teratogenic agent" ;
rdfs:comment "A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:WBPhenotype_0001004 a rdfs:Class ;
rdfs:label "pharyngeal relaxation variant" ;
rdfs:comment "Any variation in the relaxation of pharyngeal muscles after contraction events compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000634 .
obo:GO_2001243 a rdfs:Class ;
rdfs:label "negative regulation of intrinsic apoptotic signaling pathway" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902532 , obo:GO_2001234 , obo:GO_2001242 .
obo:WBls_0000018 a rdfs:Class ;
rdfs:label "1.5-fold embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000806 .
obo:RO_0002087 a rdf:Property ;
rdfs:label "starts_at_end_of" ;
rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:BFO_0000062 .
obo:GO_0007084 a rdfs:Class ;
rdfs:label "mitotic nuclear membrane reassembly" ;
rdfs:comment "The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge." ;
rdfs:subClassOf obo:GO_0031468 , obo:GO_0101024 .
obo:WBPhenotype_0001087 a rdfs:Class ;
rdfs:label "acetone chemotaxis defective" ;
rdfs:comment "Failure to execute characteristic response to acetone compared to control. In C. elegans, animals move towards typically attractive concentrations of acetone." ;
rdfs:subClassOf obo:WBPhenotype_0001438 , obo:WBPhenotype_0001465 .
obo:BFO_0000017 a rdfs:Class ;
rdfs:label "realizable entity"@en ;
rdfs:comment "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
rdfs:subClassOf obo:BFO_0000020 .
obo:WBPhenotype_0002035 a rdfs:Class ;
rdfs:label "resistant to lectin" ;
rdfs:comment "Exposure to lectin has no affect on the behavior, growth, or development of the animal compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002031 .
obo:GO_0007091 a rdfs:Class ;
rdfs:label "metaphase/anaphase transition of mitotic cell cycle" ;
rdfs:comment "The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ;
rdfs:subClassOf obo:GO_0044772 , obo:GO_0044784 .
obo:WBPhenotype_0000067 a rdfs:Class ;
rdfs:label "organism stress response variant" ;
rdfs:comment "Animals exhibit variations in response to stress stimuli compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:PATO_0002303 a rdfs:Class ;
rdfs:label "decreased object quality" ;
rdfs:comment "A quality of an object that has a value that is decreased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0001241 , obo:PATO_0002301 .
obo:RO_0015008 a rdf:Property ;
rdfs:range .
obo:CHEBI_26456 a rdfs:Class ;
rdfs:label "pyrrolidine alkaloid" ;
rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_38260 .
obo:GO_0040021 a rdfs:Class ;
rdfs:label "hermaphrodite germ-line sex determination" ;
rdfs:comment "The determination of sex and sexual phenotype in the germ line of a hermaphrodite." ;
rdfs:subClassOf obo:GO_0018992 .
obo:CHEBI_16235 a rdfs:Class ;
rdfs:label "guanine" ;
rdfs:comment "A 2-aminopurine carrying a 6-oxo substituent." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_20702 , obo:CHEBI_25810 , obo:CHEBI_26386 .
obo:GO_0006998 a rdfs:Class ;
rdfs:label "nuclear envelope organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." ;
rdfs:subClassOf obo:GO_0061024 .
obo:GO_1900408 a rdfs:Class ;
rdfs:label "negative regulation of cellular response to oxidative stress" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0065007 , obo:GO_1900407 , obo:GO_1902883 .
obo:WBPhenotype_0001415 a rdfs:Class ;
rdfs:label "pathogen adherence variant" ;
rdfs:comment "Animals exhibit variations that result in variations in the ability of or extent to which pathogens adhere to the surface of animals, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001012 .
obo:WBPhenotype_0002104 a rdfs:Class ;
rdfs:label "recycling endosome localization variant" ;
rdfs:comment "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
rdfs:subClassOf obo:WBPhenotype_0002100 .
obo:WBPhenotype_0000031 a rdfs:Class ;
rdfs:label "slow growth" ;
rdfs:comment "Any variation that causes a reduction in growth rate compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000043 , obo:WBPhenotype_0000438 , obo:WBPhenotype_0000676 .
obo:GO_1905037 a rdfs:Class ;
rdfs:label "autophagosome organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome." ;
rdfs:subClassOf obo:GO_0007033 .
obo:WBPhenotype_0001462 a rdfs:Class ;
rdfs:label "sodium chloride chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium chloride. In C. elegans, at specific concentrations, sodium chloride is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001047 .
obo:WBPhenotype_0001964 a rdfs:Class ;
rdfs:label "dopaminergic fate atypical" ;
rdfs:comment "Animals exhibit differential regulation of the dopaminergic fate among the various classes of dopaminergic neurons." ;
rdfs:subClassOf obo:WBPhenotype_0001510 .
obo:UBERON_0000465 a rdfs:Class ;
rdfs:label "material anatomical entity" ;
rdfs:comment "Anatomical entity that has mass." ;
rdfs:subClassOf obo:BFO_0000040 , obo:UBERON_0001062 .
obo:WBPhenotype_0000319 a rdfs:Class ;
rdfs:label "large" ;
rdfs:comment "Animals have increased girth and increased length compared to control animals at the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0000231 , obo:WBPhenotype_0002555 .
obo:WBPhenotype_0000346 a rdfs:Class ;
rdfs:label "adult pigmentation variant" ;
rdfs:comment "Adult animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001009 .
obo:WBPhenotype_0002602 a rdfs:Class ;
rdfs:label "reduced frequency of spontaneous reversal initiation"@en ;
rdfs:comment "Animals exhibit a decrease in the rate at which spontaneous backward locomotion is initiated compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001506 .
obo:PATO_0000964 a rdfs:Class ;
rdfs:label "transparent" ;
rdfs:comment "A optical quality inhering in a bearer by virtue of the bearer's lacking opacity." ;
rdfs:subClassOf obo:PATO_0000957 .
obo:WBPhenotype_0000692 a rdfs:Class ;
rdfs:label "male sterile" ;
rdfs:comment "X0 animals fail to generate viable cross-progeny." ;
rdfs:subClassOf obo:WBPhenotype_0000688 , obo:WBPhenotype_0000863 .
obo:WBPhenotype_0002046 a rdfs:Class ;
rdfs:label "iron homeostasis variant" ;
rdfs:comment "Variations in the regulation of levels, transport, and metabolism of iron within an organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002029 .
obo:CHEBI_25216 a rdfs:Class ;
rdfs:label "metalloporphyrin" ;
rdfs:subClassOf obo:CHEBI_26214 , obo:CHEBI_33240 , obo:CHEBI_33909 .
obo:WBPhenotype_0000732 a rdfs:Class ;
rdfs:label "DNA metabolism variant" ;
rdfs:comment "Variations in any process that involves the maintenance, biosynthesis or accumulation of DNA in the organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000463 , obo:WBPhenotype_0000585 .
obo:GO_0019336 a rdfs:Class ;
rdfs:label "phenol-containing compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0018958 .
obo:WBPhenotype_0001149 a rdfs:Class ;
rdfs:label "obsolete polar body reabsorbed first early emb" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0002510 a rdfs:Class ;
rdfs:label "fewer neurons"@en ;
rdfs:comment "Animals exhibit fewer neurons compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000623 , obo:WBPhenotype_0002174 .
obo:GO_0032062 a rdfs:Class ;
rdfs:label "positive regulation of translation in response to osmotic stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ;
rdfs:subClassOf obo:GO_0032056 , obo:GO_0043557 , obo:GO_0065007 .
obo:GO_1905941 a rdfs:Class ;
rdfs:label "positive regulation of gonad development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of gonad development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1905939 , obo:GO_2000243 .
obo:GO_0140640 a rdfs:Class ;
rdfs:label "catalytic activity, acting on a nucleic acid" ;
rdfs:comment "Catalytic activity that acts to modify a nucleic acid." ;
rdfs:subClassOf obo:GO_0003824 .
obo:CHEBI_86991 a rdfs:Class ;
rdfs:label "(R)-fluoxetine" ;
rdfs:comment "An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has R configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine]." ;
rdfs:subClassOf obo:CHEBI_86990 .
obo:GO_0060283 a rdfs:Class ;
rdfs:label "negative regulation of oocyte development" ;
rdfs:comment "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0060281 , obo:GO_0065007 , obo:GO_2000242 .
obo:WBPhenotype_0000749 a rdfs:Class ;
rdfs:label "embryonic development variant" ;
rdfs:comment "Variations in the progression of an embryo over time, from zygote formation to hatching compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000531 .
obo:PATO_0001029 a rdfs:Class ;
rdfs:label "efficiency" ;
rdfs:comment "A physical quality inhering in a bearer by virtue of ratio of the bearer's output to the bearer's input." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:CHEBI_74634 a rdfs:Class ;
rdfs:label "cardenolides" ;
rdfs:comment "Any steroid lactone that is a C23 steroid with a five-membered lactone ring at C-17 and its substituted derivatives. They form the aglycone constituents of cardiac glycosides." ;
rdfs:subClassOf obo:CHEBI_26766 , obo:CHEBI_50523 .
obo:WBPhenotype_0000989 a rdfs:Class ;
rdfs:label "marginal cell physiology variant" ;
rdfs:comment "Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for a marginal cell to carry out its normal function and activities or be able to perceive and respond to stimuli." ;
rdfs:subClassOf obo:WBPhenotype_0000986 , obo:WBPhenotype_0001190 .
obo:CHEBI_33405 a rdfs:Class ;
rdfs:label "hydracid" ;
rdfs:comment "A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33608 .
obo:WBPhenotype_0000565 a rdfs:Class ;
rdfs:label "coiler" ;
rdfs:comment "The body of an animal assumes a coil-like shape when it attempts to move." ;
rdfs:subClassOf obo:WBPhenotype_0002297 , obo:WBPhenotype_0004017 .
obo:GO_0008610 a rdfs:Class ;
rdfs:label "lipid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." ;
rdfs:subClassOf obo:GO_0006629 , obo:GO_0009058 .
obo:WBPhenotype_0000252 a rdfs:Class ;
rdfs:label "caffeine resistant" ;
rdfs:comment "Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 .
obo:WBPhenotype_0001365 a rdfs:Class ;
rdfs:label "male bursa development variant" ;
rdfs:comment "Any variation in the process whose specific outcome is the progression of the male bursa over time, from its formation to the mature structure, compared to control. The male bursa consists of the lateral fan and rays (WormAtlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001297 .
obo:GO_0007057 a rdfs:Class ;
rdfs:label "spindle assembly involved in female meiosis I" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0007056 , obo:GO_0051225 .
obo:GO_0018958 a rdfs:Class ;
rdfs:label "phenol-containing compound metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ;
rdfs:subClassOf obo:GO_0008152 .
obo:CHEBI_78017 a rdfs:Class ;
rdfs:label "food propellant" ;
rdfs:comment "A propellant that is used to expel foods from an aerosol container." ;
rdfs:subClassOf obo:CHEBI_64047 , obo:CHEBI_76414 .
obo:GO_0060097 a rdfs:Class ;
rdfs:label "cytoskeletal rearrangement involved in phagocytosis, engulfment" ;
rdfs:comment "The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ;
rdfs:subClassOf obo:GO_0007010 .
obo:GO_1905166 a rdfs:Class ;
rdfs:label "negative regulation of lysosomal protein catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904351 , obo:GO_1905165 .
obo:WBPhenotype_0001929 a rdfs:Class ;
rdfs:label "linker cell absent" ;
rdfs:comment "The gonads of male animals do not produce the linker cell involved in guiding the developing male gonad to the sex organs in the male tail." ;
rdfs:subClassOf obo:WBPhenotype_0001675 , obo:WBPhenotype_0002174 , obo:WBPhenotype_0002552 .
obo:CHEBI_35623 a rdfs:Class ;
rdfs:label "anticonvulsant" ;
rdfs:comment "A drug used to prevent seizures or reduce their severity." ;
rdfs:subClassOf obo:CHEBI_35488 .
obo:WBPhenotype_0001354 a rdfs:Class ;
rdfs:label "actin cytoskeleton filament morphology phenotype" ;
rdfs:comment "Animals exhibit variations in the form, structure, composition or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001587 .
obo:WBPhenotype_0000241 a rdfs:Class ;
rdfs:label "accumulated cell corpses" ;
rdfs:comment "Animals exhibit an increase in the quantity of cells that have undergone programmed cell death but have not been engulfed." ;
rdfs:subClassOf obo:WBPhenotype_0000590 .
obo:WBPhenotype_0000812 a rdfs:Class ;
rdfs:label "germ cell development variant" ;
rdfs:comment "Variations in the progression of the immature germ cell over time, from its formation from precursors to the mature structure (gamete) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000774 .
obo:CHEBI_33457 a rdfs:Class ;
rdfs:label "phosphorus oxoacid" ;
rdfs:comment "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." ;
rdfs:subClassOf obo:CHEBI_33408 , obo:CHEBI_36360 .
obo:WBls_0000029 a rdfs:Class ;
rdfs:label "L2-L3 molt Ce" ;
rdfs:comment "The stage when an animal shifts from L2 larva to L3 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000824 .
obo:WBPhenotype_0001336 a rdfs:Class ;
rdfs:label "male mating efficiency eliminated" ;
rdfs:comment "Males sire no cross progeny." ;
rdfs:subClassOf obo:WBPhenotype_0000843 .
obo:GO_1904411 a rdfs:Class ;
rdfs:label "positive regulation of secretory granule organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of secretory granule organization." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0065007 , obo:GO_1904409 .
obo:WBPhenotype_0002504 a rdfs:Class ;
rdfs:label "pathogen release reduced"@en ;
rdfs:comment "Infected animals exhibit a reduction in the release of pathogens back into the environment, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002172 .
obo:CHEBI_22728 a rdfs:Class ;
rdfs:label "benzopyrrole" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 , obo:CHEBI_38180 .
obo:CHEBI_25701 a rdfs:Class ;
rdfs:label "organic oxide" ;
rdfs:comment "An oxide in which the oxygen atom is bonded to a carbon atom." ;
rdfs:subClassOf obo:CHEBI_25741 , obo:CHEBI_72695 .
obo:CHEBI_25693 a rdfs:Class ;
rdfs:label "organic heteromonocyclic compound" ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33670 .
obo:GO_0005515 a rdfs:Class ;
rdfs:label "protein binding" ;
rdfs:comment "Binding to a protein." ;
rdfs:subClassOf obo:GO_0005488 .
obo:CHEBI_17137 a rdfs:Class ;
rdfs:label "hydrogensulfite" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33482 .
obo:CL_0000154 a rdfs:Class ;
rdfs:label "protein secreting cell" ;
rdfs:comment "Any secretory cell that is capable of some protein secretion." ;
rdfs:subClassOf obo:CL_0000151 .
obo:WBPhenotype_0000562 a rdfs:Class ;
rdfs:label "body levamisole resistant" ;
rdfs:comment "The bodies of animals fail to respond to the concentration of levamisole that elicits a response in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000421 .
obo:WBPhenotype_0002050 a rdfs:Class ;
rdfs:label "abamectin sensitive" ;
rdfs:comment "Animals are do not survive, or become paralyzed in the presence of abamectin." ;
rdfs:subClassOf obo:WBPhenotype_0001918 , obo:WBPhenotype_0002049 .
obo:CHEBI_84735 a rdfs:Class ;
rdfs:label "algal metabolite" ;
rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." ;
rdfs:subClassOf obo:CHEBI_75763 .
obo:WBbt_0005237 a rdfs:Class ;
rdfs:label "touch receptor neuron" ;
rdfs:comment "neurons that sense body touch, have specialized microtubules in processes." ;
rdfs:subClassOf obo:WBbt_0008431 .
obo:WBPhenotype_0000298 a rdfs:Class ;
rdfs:label "rays displaced" ;
rdfs:comment "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are shifted from their customary place." ;
rdfs:subClassOf obo:WBPhenotype_0000505 .
obo:WBPhenotype_0001745 a rdfs:Class ;
rdfs:label "adherens junction variant" ;
rdfs:comment "Any variation in a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001658 .
obo:CHEBI_28790 a rdfs:Class ;
rdfs:label "serotonin" ;
rdfs:comment "A primary amino compound that is the 5-hydroxy derivative of tryptamine." ;
rdfs:subClassOf obo:CHEBI_25375 , obo:CHEBI_27162 , obo:CHEBI_33853 , obo:CHEBI_50994 , obo:CHEBI_84729 .
obo:CHEBI_58942 a rdfs:Class ;
rdfs:label "cationic amino-acid residue" ;
rdfs:comment "An amino-acid residue protonated on nitrogen." ;
rdfs:subClassOf obo:CHEBI_64769 .
obo:WBPhenotype_0000119 a rdfs:Class ;
rdfs:label "protein expression increased" ;
rdfs:comment "Any change that results in higher than normal levels of protein expression compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001400 .
obo:GO_0007517 a rdfs:Class ;
rdfs:label "muscle organ development" ;
rdfs:comment "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0061061 .
obo:WBPhenotype_0001835 a rdfs:Class ;
rdfs:label "energy expenditure variant" ;
rdfs:comment "Variations in the amount of energy consumed by an organism compared to control. Energy expenditure is often determined by assaying oxygen consumption." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0000122 a rdfs:Class ;
rdfs:label "post translational processing variant" ;
rdfs:comment "Any variation in the posttranslational modification of a protein (which may include cleavage of peptide bonds) leading to the attainment of the full functional capacity of the protein compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0000424 a rdfs:Class ;
rdfs:label "antibody staining variant" ;
rdfs:comment "Any variation in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000112 .
obo:WBPhenotype_0002658 a rdfs:Class ;
rdfs:label "muscle strength phenotype"@en ;
rdfs:comment "Animals exhibit variations in muscle strength, as measured by a strength determining assay, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000611 .
obo:WBbt_0004017 a rdfs:Class ;
rdfs:label "Cell" ;
rdfs:comment "a cellular object that consists of subcellular components, expresses genes or functions." ;
rdfs:subClassOf obo:WBbt_0000100 .
obo:GO_0006264 a rdfs:Class ;
rdfs:label "mitochondrial DNA replication" ;
rdfs:comment "The process in which new strands of DNA are synthesized in the mitochondrion." ;
rdfs:subClassOf obo:GO_0006260 , obo:GO_0006261 , obo:GO_0032042 .
obo:GO_0045806 a rdfs:Class ;
rdfs:label "negative regulation of endocytosis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis." ;
rdfs:subClassOf obo:GO_0030100 , obo:GO_0051051 , obo:GO_0051129 , obo:GO_0065007 .
obo:WBPhenotype_0001380 a rdfs:Class ;
rdfs:label "anoxia hypersensitive" ;
rdfs:comment "Animals respond to anoxic (trace oxygen levels) stress after a shorter exposure time compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002424 .
obo:GO_0070586 a rdfs:Class ;
rdfs:label "cell-cell adhesion involved in gastrulation" ;
rdfs:comment "The attachment of one cell to another cell affecting gastrulation." ;
rdfs:subClassOf obo:GO_0098609 .
obo:CHEBI_27134 a rdfs:Class ;
rdfs:label "trimethylxanthine" ;
rdfs:subClassOf obo:CHEBI_25348 .
obo:WBPhenotype_0001118 a rdfs:Class ;
rdfs:label "cell position defective early emb" ;
rdfs:comment "Cell position is abnormal in the early embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0002402 .
obo:WBPhenotype_0001231 a rdfs:Class ;
rdfs:label "intraflagellar transport accelerated" ;
rdfs:comment "The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is increased compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000853 .
obo:CHEBI_18243 a rdfs:Class ;
rdfs:label "dopamine" ;
rdfs:comment "Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group." ;
rdfs:subClassOf obo:CHEBI_33567 .
obo:WBPhenotype_0001875 a rdfs:Class ;
rdfs:label "anaphase bridging" ;
rdfs:comment "Chromosomal masses fail to fully separate and remained linked during anaphase." ;
rdfs:subClassOf obo:WBPhenotype_0001378 .
obo:GO_0009408 a rdfs:Class ;
rdfs:label "response to heat" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0009266 .
obo:WBPhenotype_0000681 a rdfs:Class ;
rdfs:label "DMPP response variant" ;
rdfs:comment "Animals exhibit variations in their response to DMPP compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0001794 a rdfs:Class ;
rdfs:label "cytoplasmic processing body variant" ;
rdfs:comment "Discrete foci within the cytoplasm containing congregations of mRNA translational suppression and degradation mechanisms vary in their arrangement, clustering or are otherwise not well-defined compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001300 .
obo:GO_1900120 a rdfs:Class ;
rdfs:label "regulation of receptor binding" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor." ;
rdfs:subClassOf obo:GO_0043393 , obo:GO_0065007 .
obo:WBPhenotype_0001756 a rdfs:Class ;
rdfs:label "UV induced apoptosis decreased" ;
rdfs:comment "Programmed cell death caused by UV radiation is reduced compared to control animals. In C. elegans, this is often measured in the pachytene region of the gonad." ;
rdfs:subClassOf obo:WBPhenotype_0000100 .
obo:PATO_0000381 a rdfs:Class ;
rdfs:label "decreased frequency" ;
rdfs:comment "A frequency which is relatively low." ;
rdfs:subClassOf obo:PATO_0000044 , obo:PATO_0055004 .
obo:CHEBI_22928 a rdfs:Class ;
rdfs:label "bromine molecular entity" ;
rdfs:subClassOf obo:CHEBI_24471 .
obo:WBPhenotype_0002221 a rdfs:Class ;
rdfs:label "pharyngeal vacuole" ;
rdfs:comment "The pharynx contains cavities, possibly indicative of inappropriate cell death." ;
rdfs:subClassOf obo:WBPhenotype_0001363 , obo:WBPhenotype_0002615 .
obo:WBPhenotype_0002669 a rdfs:Class ;
rdfs:label "diminished motivation after food deprivation"@en ;
rdfs:comment "Animals exhibit diminished motivation after food deprivation/starvation as indicated by, for example, reduced foraging and immobility, compared to controls" ;
rdfs:subClassOf obo:WBPhenotype_0000147 .
obo:GO_0042335 a rdfs:Class ;
rdfs:label "cuticle development" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0055080 a rdfs:Class ;
rdfs:label "monoatomic cation homeostasis" ;
rdfs:comment "Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." ;
rdfs:subClassOf obo:GO_0050801 .
obo:GO_0141187 a rdfs:Class ;
rdfs:label "nucleic acid biosynthetic process" ;
rdfs:comment "The biosynthetic process resulting in the formation of a nucleic acid." ;
rdfs:subClassOf obo:GO_0009059 , obo:GO_0034654 , obo:GO_0090304 .
obo:GO_0006338 a rdfs:Class ;
rdfs:label "chromatin remodeling" ;
rdfs:comment "A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication." ;
rdfs:subClassOf obo:GO_0006325 .
obo:WBPhenotype_0002330 a rdfs:Class ;
rdfs:label "obsolete temporal frequency of sinusoidal movement decreased" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000576 a rdfs:Class ;
rdfs:label "organism physiology phenotype" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the organism to carry out its normal function or be able to perceive and respond to stimuli." ;
rdfs:subClassOf obo:WBPhenotype_0000519 .
obo:CHEBI_64271 a rdfs:Class ;
rdfs:label "tunicamycin D1" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a heptadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:CHEBI_76967 a rdfs:Class ;
rdfs:label "human xenobiotic metabolite" ;
rdfs:comment "Any human metabolite produced by metabolism of a xenobiotic compound in humans." ;
rdfs:subClassOf obo:CHEBI_76206 , obo:CHEBI_77746 .
obo:WBPhenotype_0000919 a rdfs:Class ;
rdfs:label "body wall muscle cell spindle development variant" ;
rdfs:comment "Any variation in the progression of the region of a body wall muscle cell that contains the myofilament lattice (adjacent to the hypodermis) over time, from its initial state to the fully differentiated state compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000087 .
obo:GO_0010968 a rdfs:Class ;
rdfs:label "regulation of microtubule nucleation" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." ;
rdfs:subClassOf obo:GO_0031113 , obo:GO_0065007 .
obo:WBPhenotype_0000287 a rdfs:Class ;
rdfs:label "obsolete vulval invagination L4 abnormal" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0002097 a rdfs:Class ;
rdfs:label "lysosome morphology variant" ;
rdfs:comment "Any variation in the form or composition of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002089 .
obo:WBls_0000803 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during embryogenesis"@en ;
rdfs:comment "A C. elegans life stage that occurs during embryogenesis" ;
rdfs:subClassOf obo:WBls_0000825 .
obo:GO_0055037 a rdfs:Class ;
rdfs:label "recycling endosome" ;
rdfs:comment "An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane." ;
rdfs:subClassOf obo:GO_0005768 .
obo:PATO_0001819 a rdfs:Class ;
rdfs:label "atretic" ;
rdfs:comment "A morphological quality inhering in a bearer by virtue of the bearer's absence or closure of a normal body orifice or tubular passage." ;
rdfs:subClassOf obo:PATO_0000608 .
obo:WBPhenotype_0001284 a rdfs:Class ;
rdfs:label "coenzyme Q depleted" ;
rdfs:comment "Animals contain a lower level of coenzyme Q, an oil-soluble vitamin-like substance present in most eukaryotic cells, primarily in the mitochondria, compared to control. It is a component of the electron transport chain and participates in aerobic cellular respiration." ;
rdfs:subClassOf obo:WBPhenotype_0000026 , obo:WBPhenotype_0001282 .
obo:CHEBI_79020 a rdfs:Class ;
rdfs:label "alpha,beta-unsaturated monocarboxylic acid" ;
rdfs:comment "A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C≡C bond." ;
rdfs:subClassOf obo:CHEBI_25384 .
obo:GO_0071684 a rdfs:Class ;
rdfs:label "organism emergence from protective structure" ;
rdfs:comment "The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0032109 a rdfs:Class ;
rdfs:label "positive regulation of response to nutrient levels" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a response to nutrient levels." ;
rdfs:subClassOf obo:GO_0032107 , obo:GO_0048584 , obo:GO_0065007 .
obo:WBPhenotype_0002376 a rdfs:Class ;
rdfs:label "mRNA poly-A tail length decreased" ;
rdfs:comment "Animals exhibit one or more mRNAs with decreased length of the 3' polyadenine tail, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001827 .
obo:GO_0032298 a rdfs:Class ;
rdfs:label "positive regulation of DNA-templated DNA replication initiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication." ;
rdfs:subClassOf obo:GO_0030174 , obo:GO_0065007 , obo:GO_2000105 .
obo:GO_0045904 a rdfs:Class ;
rdfs:label "negative regulation of translational termination" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination." ;
rdfs:subClassOf obo:GO_0006449 , obo:GO_0017148 , obo:GO_0043242 , obo:GO_0065007 .
obo:CHEBI_72695 a rdfs:Class ;
rdfs:label "organic molecule" ;
rdfs:comment "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." ;
rdfs:subClassOf obo:CHEBI_25367 , obo:CHEBI_50860 .
obo:WBPhenotype_0001105 a rdfs:Class ;
rdfs:label "P0 spindle position abnormal" ;
rdfs:comment "Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal." ;
rdfs:subClassOf obo:WBPhenotype_0000762 .
obo:CHEBI_38324 a rdfs:Class ;
rdfs:label "cholinergic agonist" ;
rdfs:comment "Any drug that binds to and activates cholinergic receptors." ;
rdfs:subClassOf obo:CHEBI_38323 .
obo:WBPhenotype_0002339 a rdfs:Class ;
rdfs:label "body proportion increased" ;
rdfs:comment "Animals exhibit increases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002338 .
obo:GO_0043484 a rdfs:Class ;
rdfs:label "regulation of RNA splicing" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0065007 , obo:GO_0080090 .
obo:CHEBI_36895 a rdfs:Class ;
rdfs:label "monoatomic fluorine" ;
rdfs:subClassOf obo:CHEBI_36892 .
obo:CHEBI_33848 a rdfs:Class ;
rdfs:label "polycyclic arene" ;
rdfs:comment "A polycyclic aromatic hydrocarbon." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33658 , obo:CHEBI_33666 .
obo:WBPhenotype_0000888 a rdfs:Class ;
rdfs:label "male behavior variant" ;
rdfs:comment "Animals exhibit variations in male-specific behaviors compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000821 .
obo:WBPhenotype_0002437 a rdfs:Class ;
rdfs:label "repetitive transgene expression variant" ;
rdfs:comment "Animals exhibit variations in the expression of repetitive exogenous DNA compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000306 .
obo:WBPhenotype_0002257 a rdfs:Class ;
rdfs:label "iron hypersensitive" ;
rdfs:comment "Animals respond to iron at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000591 , obo:WBPhenotype_0001918 .
obo:GO_0048285 a rdfs:Class ;
rdfs:label "organelle fission" ;
rdfs:comment "The creation of two or more organelles by division of one organelle." ;
rdfs:subClassOf obo:GO_0006996 .
obo:WBPhenotype_0001267 a rdfs:Class ;
rdfs:label "induced contraction rate variant" ;
rdfs:comment "Any variation in the frequency of gonad sheath contractions triggered by internal or external stimuli compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001199 .
obo:CL_0000075 a rdfs:Class ;
rdfs:label "columnar/cuboidal epithelial cell" ;
rdfs:comment "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ;
rdfs:subClassOf obo:CL_0000066 .
obo:GO_0019786 a rdfs:Class ;
rdfs:label "protein-phosphatidylethanolamide deconjugating activity" ;
rdfs:comment "Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue." ;
rdfs:subClassOf obo:GO_0016787 , obo:GO_0140096 .
obo:GO_0005876 a rdfs:Class ;
rdfs:label "spindle microtubule" ;
rdfs:comment "Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole." ;
rdfs:subClassOf obo:GO_0005874 .
obo:WBPhenotype_0000713 a rdfs:Class ;
rdfs:label "obsolete spermatocyte division abnormal" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000632 a rdfs:Class ;
rdfs:label "axon fasciculation variant" ;
rdfs:comment "The ability of axons to converge and form a bundle of nerve fibres (fascicle) is compromised." ;
rdfs:subClassOf obo:WBPhenotype_0000880 .
obo:GO_0007010 a rdfs:Class ;
rdfs:label "cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0006996 .
obo:WBPhenotype_0001728 a rdfs:Class ;
rdfs:label "mating plug production variant" ;
rdfs:comment "Males differ from control animals in their ability to form copulatory plugs or their placement of these plugs. In C. elegans, males of the Hawaiian strain (CB4856) typically form mating plugs." ;
rdfs:subClassOf obo:WBPhenotype_0000928 .
obo:GO_0022411 a rdfs:Class ;
rdfs:label "cellular component disassembly" ;
rdfs:comment "A cellular process that results in the breakdown of a cellular component." ;
rdfs:subClassOf obo:GO_0016043 .
obo:WBPhenotype_0001767 a rdfs:Class ;
rdfs:label "commissure handedness defective" ;
rdfs:comment "Outgrowth of the commissure occurs on the side of the body different from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000181 , obo:WBPhenotype_0000384 .
obo:GO_0050768 a rdfs:Class ;
rdfs:label "negative regulation of neurogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0050767 , obo:GO_0051961 , obo:GO_0065007 .
obo:GO_1905557 a rdfs:Class ;
rdfs:label "regulation of mitotic nuclear envelope disassembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly." ;
rdfs:subClassOf obo:GO_0010549 , obo:GO_0010564 , obo:GO_0065007 .
obo:WBPhenotype_0002317 a rdfs:Class ;
rdfs:label "dwelling increased" ;
rdfs:comment "Animals exhibit an increase in the low-speed/high turning movement that usually restricts them to a confined region compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000238 , obo:WBPhenotype_0001213 , obo:WBPhenotype_0002316 .
obo:WBPhenotype_0002232 a rdfs:Class ;
rdfs:label "synaptic remodeling variant" ;
rdfs:comment "The polarity reversal process by which synaptic components are removed from one side of the synapse and then reformed on the opposite cell does not occur or occurs in a different manner than in controls. In C. elegans, at the end of the L1 stage, the DD neurons undergo a complete polarity reversal such that the ventral synapses disappear and new synapses are formed on opposing dorsal body muscles." ;
rdfs:subClassOf obo:WBPhenotype_0000625 .
obo:GO_0032206 a rdfs:Class ;
rdfs:label "positive regulation of telomere maintenance" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." ;
rdfs:subClassOf obo:GO_0032204 , obo:GO_0051054 , obo:GO_0065007 , obo:GO_2001252 .
obo:GO_0160307 a rdfs:Class ;
rdfs:label "protein biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of protein." ;
rdfs:subClassOf obo:GO_0009059 , obo:GO_0019538 .
obo:CHEBI_35568 a rdfs:Class ;
rdfs:label "mancude ring" ;
rdfs:comment "Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:GO_0022604 a rdfs:Class ;
rdfs:label "regulation of cell morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0065007 .
obo:WBPhenotype_0000702 a rdfs:Class ;
rdfs:label "epithelial cell fusion failure" ;
rdfs:comment "Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development." ;
rdfs:subClassOf obo:WBPhenotype_0000165 , obo:WBPhenotype_0000701 .
obo:WBPhenotype_0001251 a rdfs:Class ;
rdfs:label "amphid channel axoneme short" ;
rdfs:comment "The microtuble-based fibrillar-bundles of the amphid sensory cilia are reduced in length compared to those in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001250 .
obo:WBPhenotype_0000884 a rdfs:Class ;
rdfs:label "AWB morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of either of a set of two ciliated wing neurons, AWBL or AWBR, of the amphid sensilla, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000256 , obo:WBPhenotype_0001526 .
obo:WBPhenotype_0001959 a rdfs:Class ;
rdfs:label "spindle pole pulling force variant" ;
rdfs:comment "Pulling forces on the astral microtubules at the spindle poles vary from that observed for control spindles." ;
rdfs:subClassOf obo:WBPhenotype_0002414 .
obo:CHEBI_26562 a rdfs:Class ;
rdfs:label "ribose phosphate" ;
rdfs:subClassOf obo:CHEBI_25900 .
obo:CHEBI_30145 a rdfs:Class ;
rdfs:label "lithium atom" ;
rdfs:subClassOf obo:CHEBI_22314 .
obo:WBbt_0004780 a rdfs:Class ;
rdfs:label "G1" ;
rdfs:comment "Postembryonic blast cell, excretory socket in embryo" ;
rdfs:subClassOf obo:WBbt_0007028 , obo:WBbt_0008599 .
obo:WBPhenotype_0002291 a rdfs:Class ;
rdfs:label "body posture amplitude variant" ;
rdfs:comment "Animals exhibit variations in body posture with regard to the extent of displacement measured from the mean position to an extreme position compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000001 .
obo:CHEBI_22977 a rdfs:Class ;
rdfs:label "cadmium atom" ;
rdfs:subClassOf obo:CHEBI_33340 .
obo:GO_0043170 a rdfs:Class ;
rdfs:label "macromolecule metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0008152 .
obo:WBPhenotype_0001903 a rdfs:Class ;
rdfs:label "centrosome biogenesis variant" ;
rdfs:comment "Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix). The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression." ;
rdfs:subClassOf obo:WBPhenotype_0001344 .
obo:WBbt_0003670 a rdfs:Class ;
rdfs:label "gland cell" ;
rdfs:comment "A variety of very different cell types which share cytoplasmic features (such as large membrane-bound granules) that suggest a role in secretion, thus termed gland cells." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:PATO_0001550 a rdfs:Class ;
rdfs:label "decreased sensitivity toward" ;
rdfs:comment "A sensitivity toward an external stimulus which is lower than normal/average." ;
rdfs:subClassOf obo:PATO_0000516 , obo:PATO_0002303 .
obo:WBPhenotype_0001886 a rdfs:Class ;
rdfs:label "cleavage furrow termination defective early emb" ;
rdfs:comment "Embryos exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ;
rdfs:subClassOf obo:WBPhenotype_0001129 .
obo:GO_0022008 a rdfs:Class ;
rdfs:label "neurogenesis" ;
rdfs:comment "Generation of cells within the nervous system." ;
rdfs:subClassOf obo:GO_0030154 .
obo:WBPhenotype_0001385 a rdfs:Class ;
rdfs:label "precocious oogenesis" ;
rdfs:comment "Relatively unspecialized germ cells prematurely acquire the specialized properties of mature oocytes." ;
rdfs:subClassOf obo:WBPhenotype_0000186 , obo:WBPhenotype_0000439 .
obo:CHEBI_51867 a rdfs:Class ;
rdfs:label "methyl ketone" ;
rdfs:comment "A ketone of formula RC(=O)CH3 (R ≠ H)." ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:CHEBI_36688 a rdfs:Class ;
rdfs:label "heterotricyclic compound" ;
rdfs:subClassOf obo:CHEBI_33671 .
obo:CHEBI_60895 a rdfs:Class ;
rdfs:label "D-alpha-amino acid anion" ;
rdfs:comment "Any α-amino acid anion in which the parent amino acid has D-configuration." ;
rdfs:subClassOf obo:CHEBI_33558 .
obo:WBPhenotype_0000587 a rdfs:Class ;
rdfs:label "obsolete lectin staining variant" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0001406 a rdfs:Class ;
rdfs:label "protein expression reduced male" ;
rdfs:comment "Variations that result in a decrease in protein expression in male animals compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000120 .
obo:WBPhenotype_0002145 a rdfs:Class ;
rdfs:label "siRNA processing defective" ;
rdfs:comment "Animals are unable to produce or maintain short interfering RNA (siRNA) from double stranded RNA (dsRNA). siRNAs are required to initiate interference of gene expression." ;
rdfs:subClassOf obo:WBPhenotype_0000743 , obo:WBPhenotype_0001776 .
obo:WBPhenotype_0001786 a rdfs:Class ;
rdfs:label "neuronal ion channel clustering defective" ;
rdfs:comment "Animals exhibit variations in the targeting, clustering and or maintenance of ion channels in distinct subcellular domains of the neuron compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002563 .
obo:CHEBI_60798 a rdfs:Class ;
rdfs:label "excitatory amino acid antagonist" ;
rdfs:comment "Any substance which inhibits the action of receptors for excitatory amino acids." ;
rdfs:subClassOf obo:CHEBI_48706 .
obo:CHEBI_26395 a rdfs:Class ;
rdfs:label "purine nucleotide" ;
rdfs:comment "Any nucleotide that has a purine nucleobase." ;
rdfs:subClassOf obo:CHEBI_26401 , obo:CHEBI_36976 .
obo:GO_1901990 a rdfs:Class ;
rdfs:label "regulation of mitotic cell cycle phase transition" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0065007 , obo:GO_1901987 .
obo:WBPhenotype_0000262 a rdfs:Class ;
rdfs:label "axoneme morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In C. elegans, the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center." ;
rdfs:subClassOf obo:WBPhenotype_0000615 .
obo:CHEBI_77307 a rdfs:Class ;
rdfs:label "cardioprotective agent" ;
rdfs:comment "Any protective agent that is able to prevent damage to the heart." ;
rdfs:subClassOf obo:CHEBI_50267 .
obo:WBPhenotype_0000591 a rdfs:Class ;
rdfs:label "metal response variant" ;
rdfs:comment "Animals exhibit variations in their response to a specific metal compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:WBPhenotype_0001076 a rdfs:Class ;
rdfs:label "vulval muscle homeostasis metabolism variant" ;
rdfs:comment "Variations in the chemical reactions and pathways involved in the maintenance of an internal equilibrium within the vulval muscles compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001075 .
obo:GO_1904358 a rdfs:Class ;
rdfs:label "positive regulation of telomere maintenance via telomere lengthening" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening." ;
rdfs:subClassOf obo:GO_0032206 , obo:GO_0065007 , obo:GO_1904356 .
obo:WBPhenotype_0002011 a rdfs:Class ;
rdfs:label "bivulva" ;
rdfs:comment "Animals exhibit a secondary vulval invagination that is anterior or posterior to the primary opening depending on the the inappropriate placement of daughter cells along the anterior/posterior axis during vulval development." ;
rdfs:subClassOf obo:WBPhenotype_0000695 .
obo:GO_0007618 a rdfs:Class ;
rdfs:label "mating" ;
rdfs:comment "The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes." ;
rdfs:subClassOf obo:GO_0044703 .
obo:WBPhenotype_0000873 a rdfs:Class ;
rdfs:label "G1 checkpoint variant" ;
rdfs:comment "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G1 phase of the mitotic cell cycle just before entry into S phase, compared to control cells." ;
rdfs:subClassOf obo:WBPhenotype_0000741 , obo:WBPhenotype_0001743 .
obo:WBPhenotype_0001036 a rdfs:Class ;
rdfs:label "sterile F1" ;
rdfs:comment "Any variation that compromises the reproductive ability of an F1 generation animal." ;
rdfs:subClassOf obo:WBPhenotype_0001037 .
obo:GO_0046825 a rdfs:Class ;
rdfs:label "regulation of protein export from nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm." ;
rdfs:subClassOf obo:GO_0033157 , obo:GO_0046822 , obo:GO_0065007 .
obo:GO_0036491 a rdfs:Class ;
rdfs:label "regulation of translation initiation in response to endoplasmic reticulum stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress." ;
rdfs:subClassOf obo:GO_0036490 , obo:GO_0043558 , obo:GO_0065007 .
obo:WBPhenotype_0000551 a rdfs:Class ;
rdfs:label "omega turns variant" ;
rdfs:comment "Animals exhibit variations in the rate of sharp head to tail turns compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002311 .
obo:CHEBI_59814 a rdfs:Class ;
rdfs:label "L-alpha-amino acid anion" ;
rdfs:comment "Conjugate base of an L-α-amino acid arising from deprotonation of the C-1 carboxy group." ;
rdfs:subClassOf obo:CHEBI_33558 .
obo:GO_1903306 a rdfs:Class ;
rdfs:label "negative regulation of regulated secretory pathway" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway." ;
rdfs:subClassOf obo:GO_0045920 , obo:GO_0065007 , obo:GO_1903305 .
obo:WBPhenotype_0000621 a rdfs:Class ;
rdfs:label "excretory system development variant" ;
rdfs:comment "Variations in the progression of the excretory system over time, from its formation to the mature structure. The excretory system is required for the elimination of metabolic waste. In C. elegans, the excretory system is comprised of the excretory cell, excretory duct cell and excretory socket cell." ;
rdfs:subClassOf obo:WBPhenotype_0000620 .
obo:WBPhenotype_0002185 a rdfs:Class ;
rdfs:label "cell fate transformation to endoderm" ;
rdfs:comment "Animals develop endodermal cells/tissue from precursor cells that do not normally produce endodermal cells/tissue." ;
rdfs:subClassOf obo:WBPhenotype_0000414 .
obo:GO_0044091 a rdfs:Class ;
rdfs:label "membrane biogenesis" ;
rdfs:comment "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." ;
rdfs:subClassOf obo:GO_0044085 .
obo:CHEBI_78115 a rdfs:Class ;
rdfs:label "fatty acid anion 4:0" ;
rdfs:comment "Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_58951 , obo:CHEBI_58953 .
obo:GO_2000542 a rdfs:Class ;
rdfs:label "negative regulation of gastrulation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." ;
rdfs:subClassOf obo:GO_0010470 , obo:GO_0045992 , obo:GO_0065007 .
obo:CHEBI_30512 a rdfs:Class ;
rdfs:label "silver atom" ;
rdfs:subClassOf obo:CHEBI_33366 .
obo:PATO_0000569 a rdfs:Class ;
rdfs:label "decreased height" ;
rdfs:comment "A height which is relatively low." ;
rdfs:subClassOf obo:PATO_0000119 , obo:PATO_0000587 .
obo:WBPhenotype_0000230 a rdfs:Class ;
rdfs:label "tail withered" ;
rdfs:comment "The girth of the region posterior to the vulva is reduced compared to that anterior to the vulva (the Wit phenotype). In C. elegans this phenotype is associated with anteriorward misplacement of the CAN neurons." ;
rdfs:subClassOf obo:WBPhenotype_0000073 .
obo:WBPhenotype_0000308 a rdfs:Class ;
rdfs:label "dauer development phenotype" ;
rdfs:comment "Any variation in the processes that govern development of the dauer larva, a developmentally arrested, larval stage that is specialized for survival under harsh, or otherwise unfavorable, environmental conditions. In C. elegans this is an alternative third larval stage." ;
rdfs:subClassOf obo:WBPhenotype_0000750 , obo:WBPhenotype_0002527 .
obo:WBPhenotype_0002494 a rdfs:Class ;
rdfs:label "ectopic endoderm"@en ;
rdfs:comment "Animals exhibit one or more endodermal cells in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0002493 .
obo:CHEBI_50795 a rdfs:Class ;
rdfs:label "nanostructure" ;
rdfs:comment "A nanometre sized object." ;
rdfs:subClassOf obo:CHEBI_36357 .
obo:GO_0008356 a rdfs:Class ;
rdfs:label "asymmetric cell division" ;
rdfs:comment "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." ;
rdfs:subClassOf obo:GO_0051301 .
obo:CHEBI_64018 a rdfs:Class ;
rdfs:label "protein kinase C agonist" ;
rdfs:comment "An agonist that selectively binds to and activates a protein kinase C receptor" ;
rdfs:subClassOf obo:CHEBI_64106 .
obo:WBPhenotype_0001037 a rdfs:Class ;
rdfs:label "sterile progeny" ;
rdfs:comment "Any variation that compromises the reproductive ability of the progeny of an animal." ;
rdfs:subClassOf obo:WBPhenotype_0000069 , obo:WBPhenotype_0000688 .
obo:CHEBI_23981 a rdfs:Class ;
rdfs:label "ethanolamines" ;
rdfs:subClassOf obo:CHEBI_22478 .
obo:GO_0030857 a rdfs:Class ;
rdfs:label "negative regulation of epithelial cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." ;
rdfs:subClassOf obo:GO_0030856 , obo:GO_0045596 , obo:GO_0065007 .
obo:WBPhenotype_0001289 a rdfs:Class ;
rdfs:label "acetylcholinesterase inhibitor resistant" ;
rdfs:comment "Animals fail to respond to the concentration of acetylcholinesterase inhibitor that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001290 .
obo:WBPhenotype_0001846 a rdfs:Class ;
rdfs:label "phagosome maturation defective" ;
rdfs:comment "Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes." ;
rdfs:subClassOf obo:WBPhenotype_0000885 .
obo:GO_0051130 a rdfs:Class ;
rdfs:label "positive regulation of cellular component organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0051128 , obo:GO_0065007 .
obo:PATO_0000502 a rdfs:Class ;
rdfs:label "delayed" ;
rdfs:comment "A quality of a process which starts later than the natural start time or the reference process." ;
rdfs:subClassOf obo:PATO_0002325 .
obo:CHEBI_68452 a rdfs:Class ;
rdfs:label "azole" ;
rdfs:comment "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen." ;
rdfs:subClassOf obo:CHEBI_38101 , obo:CHEBI_38179 .
obo:WBPhenotype_0002190 a rdfs:Class ;
rdfs:label "fewer hypodermal cells" ;
rdfs:comment "The population of hypodermal cells is reduced compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002174 .
obo:WBPhenotype_0002068 a rdfs:Class ;
rdfs:label "astral microtubule asymmetry defective" ;
rdfs:comment "There is significantly less difference between the number of astral microtubles or other component(s) of the spindle microtuble organizing center at the anterior versus posterior poles of the spindle, than observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002419 .
obo:CHEBI_30185 a rdfs:Class ;
rdfs:label "zinc(0)" ;
rdfs:subClassOf obo:CHEBI_37253 .
obo:WBbt_0008209 a rdfs:Class ;
rdfs:label "male gonadal cell" ;
rdfs:comment "cell of male gonad." ;
rdfs:subClassOf obo:WBbt_0004017 , obo:WBbt_0005757 .
obo:CHEBI_50047 a rdfs:Class ;
rdfs:label "organic amino compound" ;
rdfs:comment "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35352 .
obo:WBPhenotype_0001706 a rdfs:Class ;
rdfs:label "nuclear export defective" ;
rdfs:comment "The directed movement of substances out of the nucleus is impaired." ;
rdfs:subClassOf obo:WBPhenotype_0001705 .
obo:PATO_0055004 a rdfs:Class ;
rdfs:label "decreased rate of occurrence" ;
rdfs:comment "A rate of occurrence that is relatively low." ;
rdfs:subClassOf obo:PATO_0000911 , obo:PATO_0050000 .
obo:CHEBI_61557 a rdfs:Class ;
rdfs:label "nucleoside 5'-triphoshate(4-)" ;
rdfs:comment "A ribonucleoside triphosphate oxoanion arising from global deprotonation of the triphosphate groups of any nucleoside triphosphate; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_59724 .
obo:GO_0120034 a rdfs:Class ;
rdfs:label "positive regulation of plasma membrane bounded cell projection assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly." ;
rdfs:subClassOf obo:GO_0031346 , obo:GO_0044089 , obo:GO_0065007 , obo:GO_0120032 .
obo:GO_0010032 a rdfs:Class ;
rdfs:label "meiotic chromosome condensation" ;
rdfs:comment "Compaction of chromatin structure prior to meiosis in eukaryotic cells." ;
rdfs:subClassOf obo:GO_0030261 , obo:GO_0070192 .
obo:GO_2000300 a rdfs:Class ;
rdfs:label "regulation of synaptic vesicle exocytosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis." ;
rdfs:subClassOf obo:GO_0046928 , obo:GO_0065007 , obo:GO_1903305 .
obo:WBPhenotype_0002515 a rdfs:Class ;
rdfs:label "organism pathogen response defective"@en ;
rdfs:comment "Animals exhibit a defective response to pathogens." ;
rdfs:subClassOf obo:WBPhenotype_0001012 .
obo:PATO_0001227 a rdfs:Class ;
rdfs:label "variant" ;
rdfs:comment "A variability quality inhering in a bearer by virtue of whether the bearer exhibits variation or change." ;
rdfs:subClassOf obo:PATO_0001303 .
obo:WBPhenotype_0001734 a rdfs:Class ;
rdfs:label "starvation suppressed pumping defective" ;
rdfs:comment "Animals deprived of food do not exhibit a decrease in pumping rate similar to that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001287 .
obo:WBPhenotype_0000801 a rdfs:Class ;
rdfs:label "ventral region development variant" ;
rdfs:comment "Variations in the progression of an animal's anatomy contained in the ventral region over time, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000578 .
obo:WBPhenotype_0001918 a rdfs:Class ;
rdfs:label "chemical hypersensitive" ;
rdfs:comment "Animals respond to a specific chemical at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:GO_2000292 a rdfs:Class ;
rdfs:label "regulation of defecation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of defecation." ;
rdfs:subClassOf obo:GO_0044058 , obo:GO_0044062 , obo:GO_0065007 .
obo:CHEBI_33792 a rdfs:Class ;
rdfs:label "canonical ribonucleoside residue" ;
rdfs:subClassOf obo:CHEBI_33791 .
obo:GO_2000241 a rdfs:Class ;
rdfs:label "regulation of reproductive process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of reproductive process." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:GO_1902533 a rdfs:Class ;
rdfs:label "positive regulation of intracellular signal transduction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." ;
rdfs:subClassOf obo:GO_0009967 , obo:GO_0065007 , obo:GO_1902531 .
obo:WBPhenotype_0002280 a rdfs:Class ;
rdfs:label "organism osmotic stress resistant" ;
rdfs:comment "Animals exhibit resistance to osmotic stress compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000876 .
obo:WBPhenotype_0000862 a rdfs:Class ;
rdfs:label "bloated" ;
rdfs:comment "Worms appears turgid or swollen as a result of an excess number of eggs being retained in the uterus." ;
rdfs:subClassOf obo:WBPhenotype_0000545 .
obo:CHEBI_84087 a rdfs:Class ;
rdfs:label "human urinary metabolite" ;
rdfs:comment "Any metabolite (endogenous or exogenous) found in human urine samples." ;
rdfs:subClassOf obo:CHEBI_77746 .
obo:WBPhenotype_0000014 a rdfs:Class ;
rdfs:label "cord commissures variant" ;
rdfs:comment "Variations in the structure, organization or path of axon tracts that grow circumferentially around the animal in a single, directed trajectory to bridge the ventral and dorsal cords, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001226 .
obo:WBPhenotype_0000278 a rdfs:Class ;
rdfs:label "body region pigmentation phenotype" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency or translucency of a particular body region." ;
rdfs:subClassOf obo:WBPhenotype_0000521 , obo:WBPhenotype_0000532 .
obo:GO_1905845 a rdfs:Class ;
rdfs:label "positive regulation of cellular response to gamma radiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0065007 , obo:GO_1905843 , obo:GO_2001230 .
obo:WBPhenotype_0000108 a rdfs:Class ;
rdfs:label "obsolete severe dumpy" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000580 a rdfs:Class ;
rdfs:label "organism segment behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of a certain body region of an animal in response to external or internal stimuli compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000522 .
obo:CHEBI_50266 a rdfs:Class ;
rdfs:label "prodrug" ;
rdfs:comment "A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug." ;
rdfs:subClassOf obo:CHEBI_136859 , obo:CHEBI_23888 .
obo:WBPhenotype_0000223 a rdfs:Class ;
rdfs:label "acetylcholine metabolism variant" ;
rdfs:comment "Animals exhibit variations in any chemical reaction or pathway involving acetylcholine, compared to control. Acetylcholine is the acetic acid ester of the organic base choline." ;
rdfs:subClassOf obo:WBPhenotype_0000221 .
obo:CL_0011115 a rdfs:Class ;
rdfs:label "precursor cell" ;
rdfs:comment "A cell that, by division or terminal differentiation, can give rise to other cell types." ;
rdfs:subClassOf obo:CL_0000000 .
obo:CHEBI_48561 a rdfs:Class ;
rdfs:label "dopaminergic antagonist" ;
rdfs:comment "A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists." ;
rdfs:subClassOf obo:CHEBI_48560 , obo:CHEBI_48706 .
obo:WBPhenotype_0000540 a rdfs:Class ;
rdfs:label "muscle arm development variant" ;
rdfs:comment "Variations in the progression of the process extension from the muscle belly by which the muscle cells reach to the nerve cords to obtain innervation over time from initial formation to mature structure compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000087 .
obo:CHEBI_32877 a rdfs:Class ;
rdfs:label "primary amine" ;
rdfs:comment "A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group." ;
rdfs:subClassOf obo:CHEBI_32952 , obo:CHEBI_50994 .
obo:WBPhenotype_0002647 a rdfs:Class ;
rdfs:label "dendrite morphology variant"@en ;
rdfs:comment "Animals display variations in the structure, organization of components, or spatial pattern of the neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001398 .
obo:CHEBI_33543 a rdfs:Class ;
rdfs:label "sulfonate" ;
rdfs:comment "The sulfur oxoanion formed by deprotonation of sulfonic acid." ;
rdfs:subClassOf obo:CHEBI_33482 .
obo:GO_0043933 a rdfs:Class ;
rdfs:label "protein-containing complex organization" ;
rdfs:comment "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." ;
rdfs:subClassOf obo:GO_0016043 .
obo:WBPhenotype_0002000 a rdfs:Class ;
rdfs:label "recovery from enhanced locomotion variant" ;
rdfs:comment "Animals that exhibit an increase in locomotion activity do not return to basal level locomotion activity at the same rate as that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000641 .
obo:WBPhenotype_0000273 a rdfs:Class ;
rdfs:label "thrashing reduced" ;
rdfs:comment "The number of body thrashes within an aqueous environment in a given period of time are reduced compared with control worms." ;
rdfs:subClassOf obo:WBPhenotype_0001700 .
obo:CHEBI_37096 a rdfs:Class ;
rdfs:label "adenosine 5'-phosphate" ;
rdfs:subClassOf obo:CHEBI_22256 .
obo:WBPhenotype_0001262 a rdfs:Class ;
rdfs:label "vulval development incomplete" ;
rdfs:comment "The developmental progression of the egg-laying organ of female and hermaphrodite nematodes is halted prior to the formation of the mature structure." ;
rdfs:subClassOf obo:WBPhenotype_0000699 .
obo:GO_0045926 a rdfs:Class ;
rdfs:label "negative regulation of growth" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." ;
rdfs:subClassOf obo:GO_0040008 , obo:GO_0048519 , obo:GO_0065007 .
obo:CHEBI_47499 a rdfs:Class ;
rdfs:label "imipramine" ;
rdfs:comment "A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_47804 .
obo:PATO_0070060 a rdfs:Class ;
rdfs:label "quality of interaction of a substance with electromagnetic radiation" ;
rdfs:comment "A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength." ;
rdfs:subClassOf obo:PATO_0002198 .
obo:UBERON_0000922 a rdfs:Class .
obo:WBPhenotype_0002420 a rdfs:Class ;
rdfs:label "chromatin modification variant" ;
rdfs:comment "Animals exhibit variations in the nature and/or extent of chromatin modification, including but not limited to acetylation and/or methylation of histones, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001382 .
obo:WBPhenotype_0001031 a rdfs:Class ;
rdfs:label "pronuclear migration reduced early emb" ;
rdfs:comment "Any variation in the movement/fusion of pronuclei in the fertilized oocyte compared to control. For example, lack of male pronuclear migration, female pronuclear migration variable, sometimes multiple female pronuclei, no or small spindle." ;
rdfs:subClassOf obo:WBPhenotype_0000511 , obo:WBPhenotype_0001152 .
obo:GO_1901978 a rdfs:Class ;
rdfs:label "positive regulation of cell cycle checkpoint" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901976 , obo:GO_1902533 .
obo:CHEBI_77023 a rdfs:Class ;
rdfs:label "EC 2.3.3.1 [citrate (Si)-synthase] inhibitor" ;
rdfs:comment "An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of citrate (Si)-synthase, EC 2.3.3.1." ;
rdfs:subClassOf obo:CHEBI_77022 .
obo:CHEBI_63332 a rdfs:Class ;
rdfs:label "EC 3.1.3.1 (alkaline phosphatase) inhibitor" ;
rdfs:comment "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1)." ;
rdfs:subClassOf obo:CHEBI_76775 .
obo:CHEBI_29108 a rdfs:Class ;
rdfs:label "calcium(2+)" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_30412 , obo:CHEBI_39123 , obo:CHEBI_60240 .
obo:CL_1100001 a rdfs:Class ;
rdfs:label "secretory epithelial cell"@en ;
rdfs:comment "An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0000151 .
obo:WBPhenotype_0000446 a rdfs:Class ;
rdfs:label "supernumerary molt" ;
rdfs:comment "Animals execute extra larval molts compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002041 .
obo:PATO_0001754 a rdfs:Class ;
rdfs:label "predisplaced growth" ;
rdfs:comment "A peramorphic growth quality which is due to an earlier onset." ;
rdfs:subClassOf obo:PATO_0001752 .
obo:GO_0030182 a rdfs:Class ;
rdfs:label "neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuron." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0000961 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial RNA catabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ;
rdfs:subClassOf obo:GO_0000960 , obo:GO_0065007 , obo:GO_1902369 .
obo:WBPhenotype_0001347 a rdfs:Class ;
rdfs:label "intestinal calcium signaling variant" ;
rdfs:comment "Any variation in the series of molecular signals in which an intestinal cell uses calcium ions to convert an extracellular signal into a response, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001093 , obo:WBPhenotype_0002170 .
obo:GO_0090232 a rdfs:Class ;
rdfs:label "positive regulation of spindle checkpoint" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090231 , obo:GO_1901978 .
obo:WBPhenotype_0000507 a rdfs:Class ;
rdfs:label "acetylcholine levels variant" ;
rdfs:comment "Animals exhibit variations in the amount of acetylcholine compared to control animals at a defined stage. Acetylcholine is the acetic acid ester of the organic base choline." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0001484 a rdfs:Class ;
rdfs:label "ammonium acetate chemotaxis defective" ;
rdfs:comment "Animals fail to execute directed movement in response to ammonium acetate. In C. elegans, ammonium acetate is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0000265 , obo:WBPhenotype_0001441 .
obo:WBPhenotype_0001123 a rdfs:Class ;
rdfs:label "synchronous second division early emb" ;
rdfs:comment "AB and P1 divide synchronously." ;
rdfs:subClassOf obo:WBPhenotype_0001120 .
obo:CHEBI_50319 a rdfs:Class ;
rdfs:label "nucleotide residue" ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:GO_0007077 a rdfs:Class ;
rdfs:label "mitotic nuclear membrane disassembly" ;
rdfs:comment "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis." ;
rdfs:subClassOf obo:GO_0051081 , obo:GO_1903047 .
obo:GO_0032467 a rdfs:Class ;
rdfs:label "positive regulation of cytokinesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." ;
rdfs:subClassOf obo:GO_0032465 , obo:GO_0051781 , obo:GO_0065007 , obo:GO_0090068 .
obo:CHEBI_48909 a rdfs:Class ;
rdfs:label "imidazothiazole" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 , obo:CHEBI_38106 .
obo:PATO_0001434 a rdfs:Class ;
rdfs:label "reproductive quality" ;
rdfs:comment "An organismal quality inhering in a bearer by virtue of the bearer's ability to produce new life or offspring." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:GO_0005694 a rdfs:Class ;
rdfs:label "chromosome" ;
rdfs:comment "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." ;
rdfs:subClassOf obo:GO_0043232 .
obo:GO_0007289 a rdfs:Class ;
rdfs:label "spermatid nucleus differentiation" ;
rdfs:comment "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization." ;
rdfs:subClassOf obo:GO_0006997 .
obo:WBPhenotype_0000547 a rdfs:Class ;
rdfs:label "starved" ;
rdfs:comment "Animals exhibit morphological characteristics that are the outcome of nutrient deprivation. In C. elegans, starved worms have fewer refractile granules in intestinal cells, making them appear pale. Strongly starved mutants are small and thin, and tend to retain fewer eggs than control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:WBPhenotype_0000926 a rdfs:Class ;
rdfs:label "body wall muscle morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the body wall muscle compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000924 .
obo:WBPhenotype_0000371 a rdfs:Class ;
rdfs:label "cell division incomplete" ;
rdfs:comment "The physical partitioning and separation of a cell into daughter cells is interupted." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:GO_0032352 a rdfs:Class ;
rdfs:label "positive regulation of hormone metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0032350 , obo:GO_0065007 .
obo:WBPhenotype_0000771 a rdfs:Class ;
rdfs:label "centrosome attachment defective early emb" ;
rdfs:comment "Centrosomes detach from the male pronucleus." ;
rdfs:subClassOf obo:WBPhenotype_0000770 , obo:WBPhenotype_0001100 , obo:WBPhenotype_0001903 .
obo:WBPhenotype_0001256 a rdfs:Class ;
rdfs:label "DNA damage induced focus formation variant" ;
rdfs:comment "Variations in the aggregation of molecules at the site of DNA strand breakage or damage compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000739 .
obo:GO_0000423 a rdfs:Class ;
rdfs:label "mitophagy" ;
rdfs:comment "The selective autophagy process in which a mitochondrion is degraded by macroautophagy." ;
rdfs:subClassOf obo:GO_0000422 , obo:GO_0016236 .
obo:WBPhenotype_0002365 a rdfs:Class ;
rdfs:label "regenerative axonal fusion defective" ;
rdfs:comment "Following axon damage, animals do not undergo axonal fusion after reconnection between the regrowing axon and its separated segment to the same extent as observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001911 .
obo:GO_0005794 a rdfs:Class ;
rdfs:label "Golgi apparatus" ;
rdfs:comment "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways." ;
rdfs:subClassOf obo:GO_0043231 .
obo:WBPhenotype_0000933 a rdfs:Class ;
rdfs:label "MS lineage variant" ;
rdfs:comment "The descendants of the MS blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000824 .
obo:GO_1905165 a rdfs:Class ;
rdfs:label "regulation of lysosomal protein catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904350 .
obo:WBPhenotype_0002086 a rdfs:Class ;
rdfs:label "crossover distribution variant" ;
rdfs:comment "The location-specific frequency of crossover events differs from that of observed in control animals, while the total number of crossover events does not significantly differ." ;
rdfs:subClassOf obo:WBPhenotype_0002083 .
obo:GO_0061659 a rdfs:Class ;
rdfs:label "ubiquitin-like protein ligase activity" ;
rdfs:comment "Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate." ;
rdfs:subClassOf obo:GO_0019787 .
obo:WBPhenotype_0001138 a rdfs:Class ;
rdfs:label "nucleus defective early emb" ;
rdfs:comment "Nucleus is abnormal in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0000764 .
obo:GO_2000252 a rdfs:Class ;
rdfs:label "negative regulation of feeding behavior" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior." ;
rdfs:subClassOf obo:GO_0048521 , obo:GO_0060259 , obo:GO_0065007 .
obo:CHEBI_35287 a rdfs:Class ;
rdfs:label "acylcholine" ;
rdfs:comment "A choline ester formed from choline and a carboxylic acid." ;
rdfs:subClassOf obo:CHEBI_35267 .
obo:WBPhenotype_0002275 a rdfs:Class ;
rdfs:label "plugged excretory pore" ;
rdfs:comment "Males receive copulatory plugs from other males, deposited on their excretory pores. This phenotype is polymorphic among C. elegans strains and also in C. briggsae." ;
rdfs:subClassOf obo:WBPhenotype_0001728 .
obo:WBPhenotype_0001296 a rdfs:Class ;
rdfs:label "lannate resistant" ;
rdfs:comment "Animals fail to respond to the concentration of lannate that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001289 , obo:WBPhenotype_0001502 .
obo:WBPhenotype_0002246 a rdfs:Class ;
rdfs:label "endogenous zinc levels increased" ;
rdfs:comment "Animals exhibit increased levels of endogenous zinc compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001849 .
obo:WBPhenotype_0001596 a rdfs:Class ;
rdfs:label "tail bobbed" ;
rdfs:comment "Swelling of the tail hypodermis resulting in a prematurely-truncated and thickened appearance of the tail. In C. elegans, this is usually applies to hermaphrodites." ;
rdfs:subClassOf obo:WBPhenotype_0000073 .
obo:WBbt_0005758 a rdfs:Class ;
rdfs:label "hermaphrodite-specific anatomical entity" ;
rdfs:comment "cells or anatomical parts specific to the hermaphrodite sex" ;
rdfs:subClassOf obo:WBbt_0005752 .
obo:WBPhenotype_0001042 a rdfs:Class ;
rdfs:label "neuron function reduced" ;
rdfs:comment "Neurons show impaired ability in the detection, transmission, coordination or their response to information about an animal's internal and external environments." ;
rdfs:subClassOf obo:WBPhenotype_0002552 , obo:WBPhenotype_0002563 .
obo:NCBITaxon_131567 a rdfs:Class .
obo:GO_0007163 a rdfs:Class ;
rdfs:label "establishment or maintenance of cell polarity" ;
rdfs:comment "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0000357 a rdfs:Class ;
rdfs:label "unfertilized oocytes laid" ;
rdfs:comment "Animals lay inactivated oocytes. In C elegans this may be due to perturbations that eliminate spermatogenesis or result in the production of defective sperm." ;
rdfs:subClassOf obo:WBPhenotype_0000640 .
obo:WBbt_0006837 a rdfs:Class ;
rdfs:label "serotonergic neuron" ;
rdfs:comment "neuron that uses serotonin as a vesicular neurotransmitter." ;
rdfs:subClassOf obo:WBbt_0003679 .
obo:GO_0032095 a rdfs:Class ;
rdfs:label "regulation of response to food" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a response to a food stimulus." ;
rdfs:subClassOf obo:GO_0032107 , obo:GO_0065007 .
obo:WBPhenotype_0002512 a rdfs:Class ;
rdfs:label "thermosensory behavior variant"@en ;
rdfs:comment "Variations in behavior that is dependent upon the sensation of temperature, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000146 , obo:WBPhenotype_0000525 .
obo:WBPhenotype_0000457 a rdfs:Class ;
rdfs:label "organism starvation hypersensitive" ;
rdfs:comment "Animals show enhanced suceptibility to deprivation of nourishment, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000147 .
obo:CHEBI_37143 a rdfs:Class ;
rdfs:label "organofluorine compound" ;
rdfs:comment "An organofluorine compound is a compound containing at least one carbon-fluorine bond." ;
rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_24062 .
obo:CHEBI_26714 a rdfs:Class ;
rdfs:label "sodium salt" ;
rdfs:comment "Any alkali metal salt having sodium(1+) as the cation." ;
rdfs:subClassOf obo:CHEBI_26712 , obo:CHEBI_35479 .
obo:GO_0040038 a rdfs:Class ;
rdfs:label "polar body extrusion after meiotic divisions" ;
rdfs:comment "The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes." ;
rdfs:subClassOf obo:GO_0033206 .
obo:CHEBI_33599 a rdfs:Class ;
rdfs:label "spiro compound" ;
rdfs:comment "A compound having one atom as the only common member of two rings." ;
rdfs:subClassOf obo:CHEBI_33635 .
obo:CHEBI_64204 a rdfs:Class ;
rdfs:label "methiothepin(2+)" ;
rdfs:comment "A doubly-charged organic cation arising from protonation of the two tertiary amino functions of methiothepin." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:WBPhenotype_0002616 a rdfs:Class ;
rdfs:label "cellular calcium level abnormal"@en ;
rdfs:comment "Cells exhibit an abnormal intracellular level (amount) of calcium, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:PATO_0000082 a rdfs:Class ;
rdfs:label "persistence" ;
rdfs:comment "A rhythm quality inhering in a bearer by virtue of the repetitiveness of bearer's rhythm." ;
rdfs:subClassOf obo:PATO_0000078 .
obo:WBPhenotype_0002585 a rdfs:Class ;
rdfs:label "predatory behavior abnormal"@en ;
rdfs:comment "Pristionchus pacificus: Animals exhibit abnormal predatory behavior, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:GO_0140096 a rdfs:Class ;
rdfs:label "catalytic activity, acting on a protein" ;
rdfs:comment "Catalytic activity that acts to modify a protein." ;
rdfs:subClassOf obo:GO_0003824 .
obo:GO_2000426 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic cell clearance" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance." ;
rdfs:subClassOf obo:GO_0050765 , obo:GO_0065007 , obo:GO_2000425 .
obo:CHEBI_17754 a rdfs:Class ;
rdfs:label "glycerol" ;
rdfs:comment "A triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_17522 , obo:CHEBI_27136 .
obo:WBPhenotype_0001199 a rdfs:Class ;
rdfs:label "gonad sheath contractions variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the contraction of a thin continuous tube surrounding the proximal portions of the ovary and covering the maturing oocytes to the near portion of the distal gonad arm, compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001198 .
obo:WBPhenotype_0002532 a rdfs:Class ;
rdfs:label "allophagy defective"@en ;
rdfs:comment "Animals exhibit defects in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded." ;
rdfs:subClassOf obo:WBPhenotype_0002531 .
obo:WBPhenotype_0001637 a rdfs:Class ;
rdfs:label "no Intestine" ;
rdfs:comment "Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells." ;
rdfs:subClassOf obo:WBPhenotype_0000708 , obo:WBPhenotype_0002174 , obo:WBPhenotype_0002553 .
obo:WBPhenotype_0001473 a rdfs:Class ;
rdfs:label "pentanol chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanol. In C. elegans, at specific concentrations, pentanol is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0000265 .
obo:GO_0031577 a rdfs:Class ;
rdfs:label "spindle checkpoint signaling" ;
rdfs:comment "A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle." ;
rdfs:subClassOf obo:GO_0000075 .
obo:WBPhenotype_0001626 a rdfs:Class ;
rdfs:label "locomotion rate serotonin variant" ;
rdfs:comment "Any variation in the locomotion rate after application of exogenous serotonin compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001232 .
obo:GO_0005730 a rdfs:Class ;
rdfs:label "nucleolus" ;
rdfs:comment "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." ;
rdfs:subClassOf obo:GO_0043232 .
obo:WBPhenotype_0000085 a rdfs:Class ;
rdfs:label "swollen intestinal lumen" ;
rdfs:comment "The intestinal lumen is expanded and can often be shown to be filled with bacteria. This swelling is distinct from distension of the entire intestine (intestinal edema)." ;
rdfs:subClassOf obo:WBPhenotype_0000710 .
obo:WBPhenotype_0000524 a rdfs:Class ;
rdfs:label "bleach response variant" ;
rdfs:comment "Animals exhibit variations in their response to bleach compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001379 , obo:WBPhenotype_0001620 .
obo:WBPhenotype_0002264 a rdfs:Class ;
rdfs:label "ATP levels increased" ;
rdfs:comment "Animals exhibit an increase in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." ;
rdfs:subClassOf obo:WBPhenotype_0001574 .
obo:CHEBI_47019 a rdfs:Class ;
rdfs:label "dihydroxytetrahydrofuran" ;
rdfs:subClassOf obo:CHEBI_47017 .
obo:CHEBI_35474 a rdfs:Class ;
rdfs:label "anxiolytic drug" ;
rdfs:comment "Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions." ;
rdfs:subClassOf obo:CHEBI_35473 .
obo:WBls_0000101 a rdfs:Class ;
rdfs:label "Nematode life stage" ;
rdfs:comment "Any developmental stage in a nematode, including embryo, larva and adult stage." ;
rdfs:subClassOf obo:WBls_0000075 .
obo:WBPhenotype_0001998 a rdfs:Class ;
rdfs:label "hypersensitive to laser ablation" ;
rdfs:comment "Animals respond more severely to laser ablation than control animals subjected to the same laser ablation conditions." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:WBPhenotype_0000328 a rdfs:Class ;
rdfs:label "terminal bulb contraction variant" ;
rdfs:comment "Variations in the rhythmic contractions of the posterior pharynx (terminal bulb), such as timing, strength etc. In C. elegans contraction of the terminal bulb inverts the grinder, allowing bacteria in front of the grinder to be broken up and transported to the intestine." ;
rdfs:subClassOf obo:WBPhenotype_0000980 .
obo:PATO_0000915 a rdfs:Class ;
rdfs:label "thickness" ;
rdfs:comment "A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width." ;
rdfs:subClassOf obo:PATO_0001708 .
obo:WBPhenotype_0000360 a rdfs:Class ;
rdfs:label "cytoplasmic streaming defective" ;
rdfs:comment "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is impaired." ;
rdfs:subClassOf obo:WBPhenotype_0002612 .
obo:CHEBI_27376 a rdfs:Class ;
rdfs:label "methanesulfonic acid" ;
rdfs:comment "An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_47901 , obo:CHEBI_64708 .
obo:WBPhenotype_0001775 a rdfs:Class ;
rdfs:label "hormetic temperature induced life span extension defective" ;
rdfs:comment "Pre-treatment with stress-inducing temperatures does not result in a life-span extension as it does in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000039 , obo:WBPhenotype_0000146 .
obo:GO_0051310 a rdfs:Class ;
rdfs:label "metaphase chromosome alignment" ;
rdfs:comment "A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division." ;
rdfs:subClassOf obo:GO_0050000 .
obo:GO_1902882 a rdfs:Class ;
rdfs:label "regulation of response to oxidative stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of response to oxidative stress." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080134 .
obo:WBPhenotype_0000760 a rdfs:Class ;
rdfs:label "spindle orientation defective early emb" ;
rdfs:comment "The alignment of the spindle relative to other cellular structures in the cells of an embryo varies from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000761 , obo:WBPhenotype_0001681 .
obo:GO_0005930 a rdfs:Class ;
rdfs:label "axoneme" ;
rdfs:comment "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0006913 a rdfs:Class ;
rdfs:label "nucleocytoplasmic transport" ;
rdfs:comment "The directed movement of molecules between the nucleus and the cytoplasm." ;
rdfs:subClassOf obo:GO_0051169 .
obo:WBPhenotype_0000405 a rdfs:Class ;
rdfs:label "giant oocytes" ;
rdfs:comment "The size of haploid female germ cells (oocytes) are significantly larger compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001260 .
obo:WBPhenotype_0000957 a rdfs:Class ;
rdfs:label "posterior lateral ganglion development variant" ;
rdfs:comment "Any variation in the progression of the neuron somata associated with the post-deirid over time from its initial formation to its mature form compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000943 .
obo:WBPhenotype_0000494 a rdfs:Class ;
rdfs:label "two fold arrest" ;
rdfs:comment "Cessation of development that normally occurs in C. elegans 460-520 min after the first cleavage at 20C, the stage between the 1.5-fold and 3-fold embryo." ;
rdfs:subClassOf obo:WBPhenotype_0000779 .
obo:GO_1903008 a rdfs:Class ;
rdfs:label "organelle disassembly" ;
rdfs:comment "The disaggregation of an organelle into its constituent components." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0022411 .
obo:CHEBI_36340 a rdfs:Class ;
rdfs:label "fermion" ;
rdfs:comment "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." ;
rdfs:subClassOf obo:CHEBI_36342 .
obo:WBPhenotype_0001161 a rdfs:Class ;
rdfs:label "maternal pronucleus indistinct early emb" ;
rdfs:comment "Maternal pronucleus has a blurry appearance. The nuclear envelope does not have a crisp circular shape." ;
rdfs:subClassOf obo:WBPhenotype_0001160 .
obo:WBPhenotype_0002014 a rdfs:Class ;
rdfs:label "current measurement variant" ;
rdfs:comment "Any observed variation in the measurement of current across the cell membrane compared to measurements in control animals. Current is a flow of electric charge through a medium." ;
rdfs:subClassOf obo:WBPhenotype_0001315 .
obo:CHEBI_33424 a rdfs:Class ;
rdfs:label "sulfur oxoacid derivative" ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_33241 .
obo:CHEBI_22951 a rdfs:Class ;
rdfs:label "butanone" ;
rdfs:comment "Any ketone that is butane substituted by an oxo group at unspecified position." ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:GO_1902803 a rdfs:Class ;
rdfs:label "regulation of synaptic vesicle transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of synaptic vesicle transport." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0051049 , obo:GO_0065007 .
obo:WBPhenotype_0000608 a rdfs:Class ;
rdfs:label "epithelial system physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the epithelial system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000575 .
obo:WBPhenotype_0001581 a rdfs:Class ;
rdfs:label "X linked gene expression enhanced" ;
rdfs:comment "Levels of transcripts associated with genes on the X chromosome are increased compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000718 .
obo:GO_0055085 a rdfs:Class ;
rdfs:label "transmembrane transport" ;
rdfs:comment "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 .
obo:GO_1905672 a rdfs:Class ;
rdfs:label "negative regulation of lysosome organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0065007 , obo:GO_1905671 .
obo:WBPhenotype_0000342 a rdfs:Class ;
rdfs:label "bursa morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the adult male tail including the lateral fan and rays compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000070 .
obo:CHEBI_71232 a rdfs:Class ;
rdfs:label "adenosine receptor antagonist" ;
rdfs:comment "An antagonist at any adenosine receptor." ;
rdfs:subClassOf obo:CHEBI_48706 .
obo:WBPhenotype_0002270 a rdfs:Class ;
rdfs:label "metabolite content decreased" ;
rdfs:comment "Animals exhibit a decrease in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism" ;
rdfs:subClassOf obo:WBPhenotype_0000463 .
obo:WBPhenotype_0002593 a rdfs:Class ;
rdfs:label "short term plate tap habituation variant"@en ;
rdfs:comment "Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s)." ;
rdfs:subClassOf obo:WBPhenotype_0002469 , obo:WBPhenotype_0002600 .
obo:GO_0043393 a rdfs:Class ;
rdfs:label "regulation of protein binding" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein binding." ;
rdfs:subClassOf obo:GO_0051098 , obo:GO_0065007 .
obo:CHEBI_37526 a rdfs:Class ;
rdfs:label "tigliane" ;
rdfs:subClassOf obo:CHEBI_35190 , obo:CHEBI_35662 .
obo:CHEBI_26932 a rdfs:Class ;
rdfs:label "tetrapyrrole" ;
rdfs:comment "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." ;
rdfs:subClassOf obo:CHEBI_33833 , obo:CHEBI_38077 .
obo:WBPhenotype_0000950 a rdfs:Class ;
rdfs:label "neuronal sheath cell development variant" ;
rdfs:comment "Any variation in the progression of a neuronal sheath cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A neuronal sheath cell is a structural cell that forms a specialized environment surrounding the sensory endings of a neuron." ;
rdfs:subClassOf obo:WBPhenotype_0000942 .
obo:WBPhenotype_0001322 a rdfs:Class ;
rdfs:label "obsolete vesicle number reduced" ;
rdfs:comment "OBSOLETE. Total presynaptic vesicle number is reduced, possibly refecting a defect in the replenishment of synaptic vesicles compared to control." .
obo:WBbt_0006830 a rdfs:Class ;
rdfs:label "HSN" ;
rdfs:comment "Neuron class of two motoneurons that innervate vulval muscles in the hermaphrodite." ;
rdfs:subClassOf obo:WBbt_0005409 , obo:WBbt_0006837 , obo:WBbt_0006840 .
obo:WBPhenotype_0001553 a rdfs:Class ;
rdfs:label "dauer excretory gland variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000914 , obo:WBPhenotype_0001545 .
obo:GO_0060623 a rdfs:Class ;
rdfs:label "regulation of chromosome condensation" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." ;
rdfs:subClassOf obo:GO_0033044 , obo:GO_0065007 .
obo:CHEBI_33558 a rdfs:Class ;
rdfs:label "alpha-amino-acid anion" ;
rdfs:comment "An amino-acid anion obtained by deprotonation of any α-amino acid." ;
rdfs:subClassOf obo:CHEBI_37022 .
obo:GO_1902669 a rdfs:Class ;
rdfs:label "positive regulation of axon guidance" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of axon guidance." ;
rdfs:subClassOf obo:GO_0010976 , obo:GO_0065007 , obo:GO_1902667 .
obo:WBPhenotype_0001391 a rdfs:Class ;
rdfs:label "gamma ray induced apoptosis increased" ;
rdfs:comment "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000183 , obo:WBPhenotype_0001326 .
obo:GO_0045727 a rdfs:Class ;
rdfs:label "positive regulation of translation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0010628 , obo:GO_0051247 , obo:GO_0065007 .
obo:WBPhenotype_0000531 a rdfs:Class ;
rdfs:label "organism development variant" ;
rdfs:comment "Any variation in the progression of a worm at any time from its fertilization to adulthood compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000518 .
obo:GO_0033554 a rdfs:Class ;
rdfs:label "cellular response to stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0051716 .
obo:GO_0048534 a rdfs:Class ;
rdfs:label "hematopoietic or lymphoid organ development" ;
rdfs:comment "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." ;
rdfs:subClassOf obo:GO_0048513 .
obo:WBPhenotype_0001525 a rdfs:Class ;
rdfs:label "terminal bulb morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of the posterior region of the pharynx compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000709 .
obo:GO_0051231 a rdfs:Class ;
rdfs:label "spindle elongation" ;
rdfs:comment "The cell cycle process in which the distance is lengthened between poles of the spindle." ;
rdfs:subClassOf obo:GO_0007017 , obo:GO_0022402 .
obo:CHEBI_33352 a rdfs:Class ;
rdfs:label "manganese group element atom" ;
rdfs:subClassOf obo:CHEBI_33561 .
obo:GO_0007623 a rdfs:Class ;
rdfs:label "circadian rhythm" ;
rdfs:comment "Any biological process in an organism that recurs with a regularity of approximately 24 hours." ;
rdfs:subClassOf obo:GO_0048511 .
obo:CHEBI_39213 a rdfs:Class ;
rdfs:label "avermectin insecticide" ;
rdfs:subClassOf obo:CHEBI_39209 , obo:CHEBI_39220 .
obo:WBPhenotype_0001069 a rdfs:Class ;
rdfs:label "increased egg laying events during active" ;
rdfs:comment "More eggs are laid during the active phase compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ;
rdfs:subClassOf obo:WBPhenotype_0001067 .
obo:GO_0032388 a rdfs:Class ;
rdfs:label "positive regulation of intracellular transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0048522 , obo:GO_0051050 , obo:GO_0065007 .
obo:GO_1903828 a rdfs:Class ;
rdfs:label "negative regulation of protein localization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0048519 , obo:GO_0065007 .
obo:WBPhenotype_0001448 a rdfs:Class ;
rdfs:label "odorant negative chemotaxis defective" ;
rdfs:comment "Animals fail to move away from repellant volatile organic chemicals." ;
rdfs:subClassOf obo:WBPhenotype_0001455 .
obo:WBPhenotype_0001932 a rdfs:Class ;
rdfs:label "myopodia present" ;
rdfs:comment "Animals exhibit ectopic plasma membrane extensions from muscle, these extensions are random projections that are thinner than the typical muscle arm." ;
rdfs:subClassOf obo:WBPhenotype_0000904 .
obo:WBPhenotype_0001101 a rdfs:Class ;
rdfs:label "egg laying response to drug variant" ;
rdfs:comment "Characteristic response to drugs with respect to egg-laying behavior varies compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000631 , obo:WBPhenotype_0000640 .
obo:WBPhenotype_0000216 a rdfs:Class ;
rdfs:label "cell fate specification variant" ;
rdfs:comment "Any variation in the processes that govern acquisition of particular cell fates compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:WBPhenotype_0002347 a rdfs:Class ;
rdfs:label "forward locomotion decreased" ;
rdfs:comment "Animals spend less time in forward locomotion, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002345 .
obo:WBPhenotype_0001195 a rdfs:Class ;
rdfs:label "generation calcium signal defective pharynx" ;
rdfs:comment "Rhythmic calcium increases in the pharynx are observed less often than in control animals. In C. elegans, rhythmic increases in intracellular calcium are often observed using a transgenically expressed cameleon, a ratiometric calcium indicator." ;
rdfs:subClassOf obo:WBPhenotype_0001192 .
obo:WBPhenotype_0001891 a rdfs:Class ;
rdfs:label "M line variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of a planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001889 .
obo:WBPhenotype_0000126 a rdfs:Class ;
rdfs:label "general pace of development defective early emb" ;
rdfs:comment "Variations in the time from pronuclei meeting to furrow initiation during the first cell division compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000043 .
obo:WBPhenotype_0000643 a rdfs:Class ;
rdfs:label "locomotion variant" ;
rdfs:comment "Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001206 .
obo:GO_1903369 a rdfs:Class ;
rdfs:label "negative regulation of foraging behavior" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior." ;
rdfs:subClassOf obo:GO_0048521 , obo:GO_0065007 , obo:GO_1903368 .
obo:GO_0060109 a rdfs:Class ;
rdfs:label "medial layer of collagen and cuticulin-based cuticle extracellular matrix" ;
rdfs:comment "The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0001611 a rdfs:Class ;
rdfs:label "halothane hypersensitive" ;
rdfs:comment "Animals respond to the lipid-soluble anesthetic halothane at lower concentrations or shorter response times compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000008 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001717 a rdfs:Class ;
rdfs:label "centroid velocity variant" ;
rdfs:comment "Animals exhibit variations in the translocation of the mean position of the rear two-thirds (centroid position) of the animal over time, from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0004025 .
obo:CL_0000086 a rdfs:Class ;
rdfs:label "obsolete germ line stem cell (sensu Nematoda and Protostomia)" ;
rdfs:comment "Obsoleted as there is no need for a term specific for nematods and protostomes." .
obo:GO_0051093 a rdfs:Class ;
rdfs:label "negative regulation of developmental process" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0050793 , obo:GO_0065007 .
obo:WBPhenotype_0000074 a rdfs:Class ;
rdfs:label "genetic pathway variant" ;
rdfs:comment "Any variation in the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000576 .
obo:PATO_0001159 a rdfs:Class ;
rdfs:label "concentrated" ;
rdfs:comment "A concentration quality inhering in a bearer by virtue of the bearer's exhibiting concentration." ;
rdfs:subClassOf obo:PATO_0000033 .
obo:RO_0015012 a rdf:Property ;
rdfs:range .
obo:WBPhenotype_0000996 a rdfs:Class ;
rdfs:label "expulsion defective" ;
rdfs:comment "Animals exhibit defects in the expulsion of gut contents. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion." ;
rdfs:subClassOf obo:WBPhenotype_0000205 .
obo:WBPhenotype_0001155 a rdfs:Class ;
rdfs:label "pronuclei meet centrally early emb" ;
rdfs:comment "The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001152 .
obo:GO_0071763 a rdfs:Class ;
rdfs:label "nuclear membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." ;
rdfs:subClassOf obo:GO_0061024 .
obo:WBPhenotype_0001116 a rdfs:Class ;
rdfs:label "absolute cell cycle timing defective early emb" ;
rdfs:comment "Absolute cell cycle timing during the first four cell divisions is aberrant." ;
rdfs:subClassOf obo:WBPhenotype_0001115 .
obo:WBPhenotype_0001830 a rdfs:Class ;
rdfs:label "response to multiple stressors variant" ;
rdfs:comment "Any variation in an animal's response to exposure to multiple stressors occuring simultaneously or during an overlapping temporal window compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:WBPhenotype_0000020 a rdfs:Class ;
rdfs:label "pharyngeal pumping irregular" ;
rdfs:comment "Pharyngeal pumping motion occurs at intervals that vary from control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001006 .
obo:WBPhenotype_0001451 a rdfs:Class ;
rdfs:label "garlic chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of garlic compared to control. In C. elegans, garlic is typically a repellant." ;
rdfs:subClassOf obo:WBPhenotype_0001450 .
obo:PATO_0000617 a rdfs:Class ;
rdfs:label "bent" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the bearer's having one or more angle(s) in its length." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:GO_0140499 a rdfs:Class ;
rdfs:label "negative regulation of mitotic spindle assembly checkpoint signaling" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0045842 , obo:GO_0062033 , obo:GO_0065007 , obo:GO_0090233 , obo:GO_0090266 .
obo:GO_0071695 a rdfs:Class ;
rdfs:label "anatomical structure maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0021700 .
obo:WBPhenotype_0000904 a rdfs:Class ;
rdfs:label "muscle cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of muscle cells compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000603 , obo:WBPhenotype_0002108 .
obo:GO_0032502 a rdfs:Class ;
rdfs:label "developmental process" ;
rdfs:comment "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." ;
rdfs:subClassOf obo:GO_0008150 .
obo:WBPhenotype_0000090 a rdfs:Class ;
rdfs:label "epidermis cuticle detached" ;
rdfs:comment "Animals are deficient in the adhesion of the cuticle to the epidermal surface of the animal." ;
rdfs:subClassOf obo:WBPhenotype_0000075 , obo:WBPhenotype_0000076 .
obo:WBPhenotype_0002554 a rdfs:Class ;
rdfs:label "organ system phenotype"@en ;
rdfs:comment "A phenotype affecting a particular organ system." ;
rdfs:subClassOf obo:WBPhenotype_0002551 .
obo:WBPhenotype_0001880 a rdfs:Class ;
rdfs:label "endoplasmic reticulum morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ;
rdfs:subClassOf obo:WBPhenotype_0002089 .
obo:CHEBI_37404 a rdfs:Class ;
rdfs:label "elemental copper" ;
rdfs:subClassOf obo:CHEBI_23377 .
obo:GO_0051447 a rdfs:Class ;
rdfs:label "negative regulation of meiotic cell cycle" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0045786 , obo:GO_0051445 , obo:GO_0065007 , obo:GO_2000242 .
obo:GO_1903421 a rdfs:Class ;
rdfs:label "regulation of synaptic vesicle recycling" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of synaptic vesicle recycling." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:GO_0007144 a rdfs:Class ;
rdfs:label "female meiosis I" ;
rdfs:comment "The cell cycle process in which the first meiotic division occurs in the female germline." ;
rdfs:subClassOf obo:GO_0007127 , obo:GO_0007143 .
obo:RO_0002093 a rdf:Property ;
rdfs:label "ends during" ;
rdfs:range .
obo:GO_0043455 a rdfs:Class ;
rdfs:label "regulation of secondary metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_0045143 a rdfs:Class ;
rdfs:label "homologous chromosome segregation" ;
rdfs:comment "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." ;
rdfs:subClassOf obo:GO_0045132 , obo:GO_0098813 .
obo:CHEBI_33703 a rdfs:Class ;
rdfs:label "amino-acid cation" ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_33702 .
obo:GO_0051703 a rdfs:Class ;
rdfs:label "biological process involved in intraspecies interaction between organisms" ;
rdfs:comment "Any process in which an organism has an effect on an organism of the same species." ;
rdfs:subClassOf obo:GO_0008150 .
obo:PATO_0001632 a rdfs:Class ;
rdfs:label "anterior to" ;
rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's being located toward the front of an organism relative to another entity." ;
rdfs:subClassOf obo:PATO_0000140 .
obo:WBPhenotype_0001570 a rdfs:Class ;
rdfs:label "body wall muscle actin organization defective" ;
rdfs:comment "The characteristic organization of actin filaments into I-bands is disrupted. In C. elegans, actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants." ;
rdfs:subClassOf obo:WBPhenotype_0000781 .
obo:WBPhenotype_0004004 a rdfs:Class ;
rdfs:label "male response to contact defective" ;
rdfs:comment "The inability of a male to respond properly to a potential mate after contact. In C.elegans, proper response includes apposing the ventral side of his tail to the hermaphrodite's body and swimming backward." ;
rdfs:subClassOf obo:WBPhenotype_0001414 , obo:WBPhenotype_0004006 , obo:WBPhenotype_0004030 .
obo:WBPhenotype_0001972 a rdfs:Class ;
rdfs:label "germ cell compartment multinucleate" ;
rdfs:comment "Germ cell compartments contain multiple nuclei." ;
rdfs:subClassOf obo:WBPhenotype_0001970 .
obo:WBPhenotype_0001290 a rdfs:Class ;
rdfs:label "acetylcholinesterase inhibitor response variant" ;
rdfs:comment "Animals exhibit variations in their response to a specific acetylcholinesterase inhibitor compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBbt_0005024 a rdfs:Class ;
rdfs:label "Z4.appp male" ;
rdfs:comment "Inner seminal vesicle cell of pedigree Z4.appap." ;
rdfs:subClassOf obo:WBbt_0008189 .
obo:GO_0031645 a rdfs:Class ;
rdfs:label "negative regulation of nervous system process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." ;
rdfs:subClassOf obo:GO_0031644 , obo:GO_0051241 , obo:GO_0065007 .
obo:PATO_0000169 a rdfs:Class ;
rdfs:label "viability" ;
rdfs:comment "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:WBPhenotype_0001829 a rdfs:Class ;
rdfs:label "premature spermatid activation" ;
rdfs:comment "Any variation that results in the premature differentiation of spermatids into motile spermatozoa compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000670 .
obo:WBPhenotype_0004031 a rdfs:Class ;
rdfs:label "mate searching variant" ;
rdfs:comment "Any variation in the ability of an animal to search for a mate compared to control. In C. elegans, this is defined by failure of the leaving assay." ;
rdfs:subClassOf obo:WBPhenotype_0004005 .
obo:WBPhenotype_0002113 a rdfs:Class ;
rdfs:label "synapsis formation variant" ;
rdfs:comment "Animals differ from controls in respect to the formation of paired chromosome loci." ;
rdfs:subClassOf obo:WBPhenotype_0002012 .
obo:GO_0034059 a rdfs:Class ;
rdfs:label "response to anoxia" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0036293 .
obo:GO_1901989 a rdfs:Class ;
rdfs:label "positive regulation of cell cycle phase transition" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell cycle phase transition." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090068 , obo:GO_1901987 .
obo:PATO_0002076 a rdfs:Class ;
rdfs:label "movement behavioral quality" ;
rdfs:comment "A behavioral quality inhering in a bearer by virtue of the bearer's movement." ;
rdfs:subClassOf obo:PATO_0000186 .
obo:CHEBI_35294 a rdfs:Class ;
rdfs:label "carbopolycyclic compound" ;
rdfs:comment "A polyclic compound in which all of the ring members are carbon atoms." ;
rdfs:subClassOf obo:CHEBI_33598 , obo:CHEBI_35295 .
obo:WBPhenotype_0000063 a rdfs:Class ;
rdfs:label "terminal arrest variable" ;
rdfs:comment "Variations that cause developmental progression to cease at different stages of the lifecycle." ;
rdfs:subClassOf obo:WBPhenotype_0000062 .
obo:CHEBI_35571 a rdfs:Class ;
rdfs:label "mancude organic heterocyclic parent" ;
rdfs:subClassOf obo:CHEBI_35552 , obo:CHEBI_35573 .
obo:WBls_0000014 a rdfs:Class ;
rdfs:label "late cleavage stage embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 210-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage before the fast cleavage of cells finishes." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000812 .
obo:CARO_0010004 a rdfs:Class .
obo:WBPhenotype_0001177 a rdfs:Class ;
rdfs:label "embryo osmotic pressure sensitive early emb" ;
rdfs:comment "Embryos rupture when placed on a 2% agar pad and covered with a coverslip." ;
rdfs:subClassOf obo:WBPhenotype_0001178 .
obo:GO_0007141 a rdfs:Class ;
rdfs:label "male meiosis I" ;
rdfs:comment "A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline." ;
rdfs:subClassOf obo:GO_0007127 , obo:GO_0007140 .
obo:CHEBI_48378 a rdfs:Class ;
rdfs:label "carboximidic acid" ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_48377 .
obo:WBPhenotype_0002158 a rdfs:Class ;
rdfs:label "P granule degradation defective" ;
rdfs:comment "The selective elimination of P granule components and subsequent aggregation of degraded components into PGL granules is disrupted." ;
rdfs:subClassOf obo:WBPhenotype_0001301 .
obo:GO_0048667 a rdfs:Class ;
rdfs:label "cell morphogenesis involved in neuron differentiation" ;
rdfs:comment "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." ;
rdfs:subClassOf obo:GO_0000902 .
obo:WBPhenotype_0001497 a rdfs:Class ;
rdfs:label "mitotic metaphase to anaphase transition defect" ;
rdfs:comment "Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids separate and migrate towards the poles of the spindle." ;
rdfs:subClassOf obo:WBPhenotype_0001496 .
obo:GO_0071027 a rdfs:Class ;
rdfs:label "nuclear RNA surveillance" ;
rdfs:comment "A process that identifies and degrades defective or aberrant RNAs within the nucleus." ;
rdfs:subClassOf obo:GO_0071025 .
obo:WBPhenotype_0000170 a rdfs:Class ;
rdfs:label "precocious alae" ;
rdfs:comment "Formation of alae occurs earlier in development compared to control animals; In C. elegans, adult lateral alae are typically generated during the late L4 stage." ;
rdfs:subClassOf obo:WBPhenotype_0000168 , obo:WBPhenotype_0000439 .
obo:WBbt_0007849 a rdfs:Class ;
rdfs:label "hermaphrodite" ;
rdfs:comment "Multi-cellular organism that can produce both male and female gametes." ;
rdfs:subClassOf obo:WBbt_0007833 .
obo:CHEBI_24129 a rdfs:Class ;
rdfs:label "furans" ;
rdfs:comment "Compounds containing at least one furan ring." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 .
obo:WBbt_0005829 a rdfs:Class ;
rdfs:label "ventral nerve cord" ;
rdfs:comment "a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:WBPhenotype_0001965 a rdfs:Class ;
rdfs:label "cell membrane physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of the cell, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0000180 a rdfs:Class ;
rdfs:label "axon morphology variant" ;
rdfs:comment "Animals display variations in the structure, organization of components, or spatial pattern of the projection that conducts signal away from the cell body, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001398 .
obo:WBPhenotype_0001058 a rdfs:Class ;
rdfs:label "potassium chemotaxis defective" ;
rdfs:comment "Animals fail to exhibit the same taxis behavior as control animals in response to potassium. In C. elegans, this is characterized by the failure of the animals to move towards potassium." ;
rdfs:subClassOf obo:WBPhenotype_0001440 .
obo:CHEBI_22917 a rdfs:Class ;
rdfs:label "phytogenic insecticide" ;
rdfs:comment "An insecticide compound naturally occurring in plants." ;
rdfs:subClassOf obo:CHEBI_24852 .
obo:WBPhenotype_0002639 a rdfs:Class ;
rdfs:label "microbiome composition abnormal"@en ;
rdfs:comment "Animals exhibit specific or general variations in the composition of the microbiome at a body site compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:WBPhenotype_0001369 a rdfs:Class ;
rdfs:label "protein interaction variant" ;
rdfs:comment "Variations in the selective and non-covalent physical association between two or more proteins, or a protein and nucleic acid/macromolecular complex, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBbt_0003760 a rdfs:Class ;
rdfs:label "organ" ;
rdfs:comment "a collection of cells or cell groups that collectively perform a function" ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:WBPhenotype_0002227 a rdfs:Class ;
rdfs:label "lead response variant" ;
rdfs:comment "Animals exhibit variations in their response to lead compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 , obo:WBPhenotype_0000591 .
obo:WBPhenotype_0002560 a rdfs:Class ;
rdfs:label "burrowing in response to high population density increased"@en ;
rdfs:comment "Greater quantities of worms burrow into and stay below the surface of the agar when high densities of nematodes are maintained on agar compared to controls (Hodgkin and Doniach, 1997)." ;
rdfs:subClassOf obo:WBPhenotype_0002559 .
obo:GO_1902230 a rdfs:Class ;
rdfs:label "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902229 , obo:GO_2001243 .
obo:WBPhenotype_0000985 a rdfs:Class ;
rdfs:label "blast cell physiology phenotype" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the blast cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:GO_0005773 a rdfs:Class ;
rdfs:label "vacuole" ;
rdfs:comment "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." ;
rdfs:subClassOf obo:GO_0043231 .
obo:WBPhenotype_0001970 a rdfs:Class ;
rdfs:label "germ cell compartment nuclei number variant" ;
rdfs:comment "Germ cell compartments contain an an atypical number on nuclei compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001969 .
obo:GO_0000398 a rdfs:Class ;
rdfs:label "mRNA splicing, via spliceosome" ;
rdfs:comment "The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." ;
rdfs:subClassOf obo:GO_0000377 , obo:GO_0006397 .
obo:CHEBI_24833 a rdfs:Class ;
rdfs:label "oxoacid" ;
rdfs:comment "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_24651 .
obo:WBPhenotype_0001242 a rdfs:Class ;
rdfs:label "intraflagellar transport slow" ;
rdfs:comment "The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is lower compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000854 .
obo:CHEBI_86995 a rdfs:Class ;
rdfs:label "(S)-fluoxetine(1+)" ;
rdfs:comment "An organic cation resulting from the protonation of the amino group of (S)-fluoxetine." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_0050848 a rdfs:Class ;
rdfs:label "regulation of calcium-mediated signaling" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902531 .
obo:CHEBI_35790 a rdfs:Class ;
rdfs:label "oxazole" ;
rdfs:comment "An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom." ;
rdfs:subClassOf obo:CHEBI_38104 , obo:CHEBI_68452 .
obo:WBPhenotype_0001605 a rdfs:Class ;
rdfs:label "extended life span response to mianserin resistant" ;
rdfs:comment "Animals do not live longer in response to mianserin compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001604 .
obo:PATO_0000937 a rdfs:Class ;
rdfs:label "disorganized" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer's lacking organisation." ;
rdfs:subClassOf obo:PATO_0002264 .
obo:GO_0010037 a rdfs:Class ;
rdfs:label "response to carbon dioxide" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus." ;
rdfs:subClassOf obo:GO_1901700 .
obo:CHEBI_38924 a rdfs:Class ;
rdfs:label "dibenzothiepine" ;
rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38106 .
obo:WBPhenotype_0001937 a rdfs:Class ;
rdfs:label "hypersensitive to protein aggregation induced paralysis" ;
rdfs:comment "Animals respond to protein aggregation at a lower concentration of aggregates or in less time compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001935 .
obo:CHEBI_28087 a rdfs:Class ;
rdfs:label "glycogen" ;
rdfs:comment "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in α(1→4) glycosidic linkage, joined together by α(1→6) glycosidic linkages. A small number of α(1→3) glycosidic linkages and some cumulative α(1→6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_24384 .
obo:WBPhenotype_0000688 a rdfs:Class ;
rdfs:label "sterile" ;
rdfs:comment "Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce." ;
rdfs:subClassOf obo:WBPhenotype_0001384 .
obo:WBPhenotype_0001818 a rdfs:Class ;
rdfs:label "neuron activation variant" ;
rdfs:comment "Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes." ;
rdfs:subClassOf obo:WBPhenotype_0002563 .
obo:GO_0006270 a rdfs:Class ;
rdfs:label "DNA replication initiation" ;
rdfs:comment "The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding." ;
rdfs:subClassOf obo:GO_0006259 .
obo:GO_0030659 a rdfs:Class ;
rdfs:label "cytoplasmic vesicle membrane" ;
rdfs:comment "The lipid bilayer surrounding a cytoplasmic vesicle." ;
rdfs:subClassOf obo:GO_0012506 , obo:GO_0016020 .
obo:WBPhenotype_0002643 a rdfs:Class ;
rdfs:label "chemical accumulation increased"@en ;
rdfs:comment "Animals exposed to an exogenous chemical exhibit an abnormal increase in accumulation of this chemical in the body of the animals, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002642 .
obo:WBPhenotype_0002169 a rdfs:Class ;
rdfs:label "reproductive longevity shortened" ;
rdfs:comment "Animals stop producing progeny significantly before the time reproduction stops in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001739 .
obo:GO_0030003 a rdfs:Class ;
rdfs:label "intracellular monoatomic cation homeostasis" ;
rdfs:comment "A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." ;
rdfs:subClassOf obo:GO_0006873 , obo:GO_0055080 .
obo:CHEBI_30297 a rdfs:Class ;
rdfs:label "antimonite" ;
rdfs:comment "A trivalent inorganic anion obtained by removal of all three protons from antimonous acid." ;
rdfs:subClassOf obo:CHEBI_36921 , obo:CHEBI_79387 .
obo:WBPhenotype_0001081 a rdfs:Class ;
rdfs:label "cytoplasmic morphology defective early emb" ;
rdfs:comment "Morphology of the cytoplasm differs from control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000769 .
obo:GO_0097091 a rdfs:Class ;
rdfs:label "synaptic vesicle clustering" ;
rdfs:comment "The process that results in grouping synaptic vesicles in presynaptic structures." ;
rdfs:subClassOf obo:GO_0097479 .
obo:WBPhenotype_0002301 a rdfs:Class ;
rdfs:label "nose movement variant" ;
rdfs:comment "The extreme anterior of the animal exhibits variations in its movement compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000662 , obo:WBPhenotype_0001699 .
obo:WBPhenotype_0002489 a rdfs:Class ;
rdfs:label "intestinal integrity reduced"@en ;
rdfs:comment "Animals exhibit a reduction in the integrity of the intestine, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002487 .
obo:GO_0033243 a rdfs:Class ;
rdfs:label "positive regulation of amine catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0033240 , obo:GO_0033241 , obo:GO_0065007 .
obo:WBPhenotype_0000603 a rdfs:Class ;
rdfs:label "muscle system morphology variant" ;
rdfs:comment "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the muscle system, compared to control. The muscle system consists of tissues made up of various elongated cells that are specialized to contract and produce movement and mechanical work." ;
rdfs:subClassOf obo:WBPhenotype_0000534 .
obo:WBbt_0008439 a rdfs:Class ;
rdfs:label "M lineage cell" ;
rdfs:comment "A cell that is the M blast cell or is a lineal descendant of M." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBPhenotype_0002654 a rdfs:Class ;
rdfs:label "exopher production in muscle phenotype"@en ;
rdfs:comment "Muscle cells exhibit an abnormal production of exophers compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000990 , obo:WBPhenotype_0002651 .
obo:GO_1904352 a rdfs:Class ;
rdfs:label "positive regulation of protein catabolic process in the vacuole" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole." ;
rdfs:subClassOf obo:GO_0045732 , obo:GO_0065007 , obo:GO_1904350 .
obo:WBPhenotype_0001797 a rdfs:Class ;
rdfs:label "pachytene arrested germline nuclei" ;
rdfs:comment "Germline nuclei do not progress through pachytene to diplotene." ;
rdfs:subClassOf obo:WBPhenotype_0001946 .
obo:WBPhenotype_0001015 a rdfs:Class ;
rdfs:label "developmental growth variant" ;
rdfs:comment "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during any development stages compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000030 .
obo:GO_0051321 a rdfs:Class ;
rdfs:label "meiotic cell cycle" ;
rdfs:comment "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." ;
rdfs:subClassOf obo:GO_0007049 , obo:GO_0022414 .
obo:WBPhenotype_0000115 a rdfs:Class ;
rdfs:label "anterior pharynx variant" ;
rdfs:comment "Any variation in the progression of the anterior portion of the pharynx over time compared to control. In C. elegans the anterior region includes the corpus (procorpus and metacorpus - first bulb)." ;
rdfs:subClassOf obo:WBPhenotype_0000707 .
obo:GO_0007088 a rdfs:Class ;
rdfs:label "regulation of mitotic nuclear division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitosis." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0010564 , obo:GO_0051783 , obo:GO_0065007 .
obo:GO_0034620 a rdfs:Class ;
rdfs:label "cellular response to unfolded protein" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus." ;
rdfs:subClassOf obo:GO_0006986 , obo:GO_0035967 .
obo:PATO_0000718 a rdfs:Class ;
rdfs:label "lethal (sensu genetics)" ;
rdfs:comment "A viability quality inhering in a population by virtue of the bearer's long term survival inability." ;
rdfs:subClassOf obo:PATO_0000169 .
obo:GO_0031112 a rdfs:Class ;
rdfs:label "positive regulation of microtubule polymerization or depolymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." ;
rdfs:subClassOf obo:GO_0031110 , obo:GO_0051495 , obo:GO_0065007 .
obo:GO_0043230 a rdfs:Class ;
rdfs:label "extracellular organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." ;
rdfs:subClassOf obo:GO_0043226 .
obo:GO_1901970 a rdfs:Class ;
rdfs:label "positive regulation of mitotic sister chromatid separation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation." ;
rdfs:subClassOf obo:GO_0010965 , obo:GO_0065007 , obo:GO_1905820 .
obo:WBbt_0006920 a rdfs:Class ;
rdfs:label "cephalic sensillum" ;
rdfs:comment "sensillum in the head, each with a CEP receptor neuron." ;
rdfs:subClassOf obo:WBbt_0006929 .
obo:WBPhenotype_0001868 a rdfs:Class ;
rdfs:label "meiotic spindle defective" ;
rdfs:comment "Cells undergoing meiosis exhibit defects in the overall function or activity of the meiotic spindle." ;
rdfs:subClassOf obo:WBPhenotype_0000775 .
obo:WBbt_0006804 a rdfs:Class ;
rdfs:label "body wall muscle cell" ;
rdfs:comment "type of 95 cells that make up muscles of the body wall." ;
rdfs:subClassOf obo:WBbt_0005779 , obo:WBbt_0007810 .
obo:WBPhenotype_0001712 a rdfs:Class ;
rdfs:label "circadian rhythm behavior variant" ;
rdfs:comment "Animals exhibit variations in the actions or reactions that recur with a periodicity associated with light/dark cycles, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001711 .
obo:GO_0006974 a rdfs:Class ;
rdfs:label "DNA damage response" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism." ;
rdfs:subClassOf obo:GO_0033554 .
obo:WBPhenotype_0001549 a rdfs:Class ;
rdfs:label "dauer gut variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion." ;
rdfs:subClassOf obo:WBPhenotype_0001545 .
obo:WBPhenotype_0000816 a rdfs:Class ;
rdfs:label "neuron development variant" ;
rdfs:comment "Variations in the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000529 , obo:WBPhenotype_0000623 .
obo:WBPhenotype_0001925 a rdfs:Class ;
rdfs:label "oocytes disorganized" ;
rdfs:comment "Oocytes are no longer arranged in the gonad in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001260 .
obo:WBPhenotype_0002044 a rdfs:Class ;
rdfs:label "hermaphrodite mating efficiency eliminated" ;
rdfs:comment "Hermaphrodites do not produce cross progeny." ;
rdfs:subClassOf obo:WBPhenotype_0002043 .
obo:WBPhenotype_0001668 a rdfs:Class ;
rdfs:label "oocyte accumulation" ;
rdfs:comment "An increased number of oocytes are retained in the gonad without becoming endomitotic, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001260 .
obo:WBPhenotype_0001273 a rdfs:Class ;
rdfs:label "organism heat response variant" ;
rdfs:comment "Any variation in the state or activity of an organism (in terms of movement, gene expression, etc.) in response to heat (high temperatures above the optimal temperature for that organism), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000146 .
obo:WBbt_0006979 a rdfs:Class ;
rdfs:label "tail spike" ;
rdfs:comment "An acellular thin cuticle whip formed at the very end of the tail during embryogenesis." ;
rdfs:subClassOf obo:WBbt_0005732 .
obo:CHEBI_25384 a rdfs:Class ;
rdfs:label "monocarboxylic acid" ;
rdfs:comment "An oxoacid containing a single carboxy group." ;
rdfs:subClassOf obo:CHEBI_33575 .
obo:CHEBI_83925 a rdfs:Class ;
rdfs:label "non-proteinogenic alpha-amino acid" ;
rdfs:comment "Any α-amino acid which is not a member of the group of 23 proteinogenic amino acids." ;
rdfs:subClassOf obo:CHEBI_33704 , obo:CHEBI_83820 .
obo:GO_0051963 a rdfs:Class ;
rdfs:label "regulation of synapse assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ;
rdfs:subClassOf obo:GO_0050807 , obo:GO_0065007 , obo:GO_1901888 .
obo:GO_0044843 a rdfs:Class ;
rdfs:label "cell cycle G1/S phase transition" ;
rdfs:comment "The cell cycle process by which a cell in G1 phase commits to S phase." ;
rdfs:subClassOf obo:GO_0044770 .
obo:CL_0002242 a rdfs:Class ;
rdfs:label "nucleate cell" ;
rdfs:comment "A cell containing at least one nucleus." ;
rdfs:subClassOf obo:CL_0000000 .
obo:WBPhenotype_0001981 a rdfs:Class ;
rdfs:label "germ cell compartment expansion absent" ;
rdfs:comment "The compartments of the germline do not increase in size." ;
rdfs:subClassOf obo:WBPhenotype_0001980 .
obo:WBPhenotype_0001752 a rdfs:Class ;
rdfs:label "vesicle trafficking variant" ;
rdfs:comment "Animals exhibit variations in vesicle-based directed movement of substances into, out of, or within a cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:GO_0051302 a rdfs:Class ;
rdfs:label "regulation of cell division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0001879 a rdfs:Class ;
rdfs:label "hydroxyurea hypersensitive" ;
rdfs:comment "Animals respond to hydroxyurea at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001878 , obo:WBPhenotype_0001918 .
obo:GO_1903034 a rdfs:Class ;
rdfs:label "regulation of response to wounding" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of response to wounding." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080134 .
obo:WBPhenotype_0001070 a rdfs:Class ;
rdfs:label "inactive phase short" ;
rdfs:comment "The period during which a worm usually does not lay eggs is short compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ;
rdfs:subClassOf obo:WBPhenotype_0001066 .
obo:GO_0019725 a rdfs:Class ;
rdfs:label "cellular homeostasis" ;
rdfs:comment "Any process involved in the maintenance of an internal steady state at the level of the cell." ;
rdfs:subClassOf obo:GO_0042592 .
obo:WBPhenotype_0002344 a rdfs:Class ;
rdfs:label "backing decreased" ;
rdfs:comment "Animals spend less time backing compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001005 .
obo:CHEBI_33853 a rdfs:Class ;
rdfs:label "phenols" ;
rdfs:comment "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_33822 .
obo:PATO_0000303 a rdfs:Class ;
rdfs:label "increased speed" ;
rdfs:comment "A speed which is relatively high." ;
rdfs:subClassOf obo:PATO_0000008 , obo:PATO_0002305 .
obo:RO_0015007 a rdf:Property ;
rdfs:range .
obo:WBbt_0007809 a rdfs:Class ;
rdfs:label "vulval precursor cell" ;
rdfs:comment "cell that has the potential to form structural part of a vulva." ;
rdfs:subClassOf obo:WBbt_0006783 .
obo:GO_0036293 a rdfs:Class ;
rdfs:label "response to decreased oxygen levels" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." ;
rdfs:subClassOf obo:GO_0070482 .
obo:GO_0050808 a rdfs:Class ;
rdfs:label "synapse organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ;
rdfs:subClassOf obo:GO_0034330 .
obo:WBPhenotype_0002084 a rdfs:Class ;
rdfs:label "crossover interference variant" ;
rdfs:comment "Animals differ from controls in respect to the frequency of expected double crossover events observed." ;
rdfs:subClassOf obo:WBPhenotype_0002083 .
obo:CHEBI_33658 a rdfs:Class ;
rdfs:label "arene" ;
rdfs:comment "Any monocyclic or polycyclic aromatic hydrocarbon." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_33663 .
obo:GO_0045120 a rdfs:Class ;
rdfs:label "pronucleus" ;
rdfs:comment "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." ;
rdfs:subClassOf obo:GO_0005634 .
obo:WBPhenotype_0001898 a rdfs:Class ;
rdfs:label "meiotic sister chromatid segregation variant" ;
rdfs:comment "Variations in the process by which sister chromatids, identical chromosomes resulting from DNA replication, are physically separated during the meiotic cell cycle, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001499 .
obo:WBbt_0005062 a rdfs:Class ;
rdfs:label "linker cell" ;
rdfs:comment "male gonad cell, leads gonad during morphogenesis and initiates union with cloaca" ;
rdfs:subClassOf obo:WBbt_0008209 .
obo:WBbt_0004804 a rdfs:Class ;
rdfs:label "E" ;
rdfs:comment "Embryonic founder cell" ;
rdfs:subClassOf obo:WBbt_0005208 , obo:WBbt_0007028 .
obo:WBPhenotype_0000164 a rdfs:Class ;
rdfs:label "thin" ;
rdfs:comment "Animals exhibit a reduced girth compared to a control animal of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0001727 .
obo:WBPhenotype_0000915 a rdfs:Class ;
rdfs:label "pale adult" ;
rdfs:comment "Adults show deficiencies in chroma resulting in increased translucency." ;
rdfs:subClassOf obo:WBPhenotype_0000346 , obo:WBPhenotype_0001261 .
obo:GO_0099098 a rdfs:Class ;
rdfs:label "microtubule polymerization based movement" ;
rdfs:comment "The movement of a cellular component as a result of microtubule polymerization." ;
rdfs:subClassOf obo:GO_0007018 .
obo:CHEBI_51422 a rdfs:Class ;
rdfs:label "organodiyl group" ;
rdfs:comment "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." ;
rdfs:subClassOf obo:CHEBI_51446 .
obo:GO_0140039 a rdfs:Class ;
rdfs:label "cell-cell adhesion in response to extracellular stimulus" ;
rdfs:comment "The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus." ;
rdfs:subClassOf obo:GO_0098609 .
obo:GO_0071478 a rdfs:Class ;
rdfs:label "cellular response to radiation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." ;
rdfs:subClassOf obo:GO_0009314 , obo:GO_0071214 .
obo:GO_1905134 a rdfs:Class ;
rdfs:label "positive regulation of meiotic chromosome separation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905132 , obo:GO_1905820 , obo:GO_2000243 .
obo:WBPhenotype_0001184 a rdfs:Class ;
rdfs:label "fat content increased" ;
rdfs:comment "Animals exhibit a greater amount of fat or lipids than observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001182 .
obo:WBPhenotype_0002003 a rdfs:Class ;
rdfs:label "hydrogen peroxide homeostasis variant" ;
rdfs:comment "Animals exhibit variations in steady-state levels of hydrogen peroxide (H2O2) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:GO_0045910 a rdfs:Class ;
rdfs:label "negative regulation of DNA recombination" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination." ;
rdfs:subClassOf obo:GO_0000018 , obo:GO_0051053 , obo:GO_0065007 .
obo:CHEBI_137982 a rdfs:Class ;
rdfs:label "tertiary ammonium ion" ;
rdfs:comment "An organic cation obtained by protonation of the amino group of any tertiary amino compound." ;
rdfs:subClassOf obo:CHEBI_25697 .
obo:WBPhenotype_0001841 a rdfs:Class ;
rdfs:label "second messenger mediated signaling variant" ;
rdfs:comment "Any variation in a series of molecular signals that help relay a receptor mediated signal within the cell, compared to control. Second messengers often comprise of ions (eg: Ca2+) or small molecules (cGMP, cAMP etc) that are formed or released into the cytosol." ;
rdfs:subClassOf obo:WBPhenotype_0000463 .
obo:GO_0007040 a rdfs:Class ;
rdfs:label "lysosome organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases." ;
rdfs:subClassOf obo:GO_0080171 .
obo:GO_0042417 a rdfs:Class ;
rdfs:label "dopamine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ;
rdfs:subClassOf obo:GO_0006584 .
obo:WBPhenotype_0001144 a rdfs:Class ;
rdfs:label "polar body number size early emb" ;
rdfs:comment "Defects are either seen in the number or size of the polar bodies in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001147 .
obo:CHEBI_48154 a rdfs:Class ;
rdfs:label "sulfur oxide" ;
rdfs:subClassOf obo:CHEBI_24836 , obo:CHEBI_26835 .
obo:WBPhenotype_0000169 a rdfs:Class ;
rdfs:label "early exit cell cycle" ;
rdfs:comment "Cells leave the M phase (mitosis and cytokinesis) at an earlier time than sister or other control cells." ;
rdfs:subClassOf obo:WBPhenotype_0001995 .
obo:GO_0007019 a rdfs:Class ;
rdfs:label "microtubule depolymerization" ;
rdfs:comment "The removal of tubulin heterodimers from one or both ends of a microtubule." ;
rdfs:subClassOf obo:GO_0031109 , obo:GO_0051261 , obo:GO_0097435 .
obo:CL_0010017 a rdfs:Class ;
rdfs:label "zygote"@en ;
rdfs:comment "A zygote in a plant or an animal." ;
rdfs:subClassOf obo:CL_0000000 .
obo:WBPhenotype_0004018 a rdfs:Class ;
rdfs:label "sinusoidal movement variant" ;
rdfs:comment "Any variation in the propagation of the contraction sine wave along the body while an animal travels from one location to another, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0004017 .
obo:WBPhenotype_0001396 a rdfs:Class ;
rdfs:label "pumping absent" ;
rdfs:comment "Animals completely lack any pharyngeal pumping motion." ;
rdfs:subClassOf obo:WBPhenotype_0001006 .
obo:GO_0031981 a rdfs:Class ;
rdfs:label "nuclear lumen" ;
rdfs:comment "The volume enclosed by the nuclear inner membrane." ;
rdfs:subClassOf obo:GO_0070013 .
obo:GO_0047484 a rdfs:Class ;
rdfs:label "regulation of response to osmotic stress" ;
rdfs:comment "Any process that modulates the rate or extent of the response to osmotic stress." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080134 .
obo:WBPhenotype_0002360 a rdfs:Class ;
rdfs:label "cold hypersensitive" ;
rdfs:comment "Animals respond more severely to cold than control animals subjected to the same cold conditions." ;
rdfs:subClassOf obo:WBPhenotype_0000146 .
obo:GO_0045785 a rdfs:Class ;
rdfs:label "positive regulation of cell adhesion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell adhesion." ;
rdfs:subClassOf obo:GO_0030155 , obo:GO_0048522 , obo:GO_0065007 .
obo:WBPhenotype_0001783 a rdfs:Class ;
rdfs:label "ligand gated channel activity variant" ;
rdfs:comment "Animals exhibit variations in the actions of a channel that catalyses the transmembrane transfer of a cation when acetylcholine has been bound by the channel complex or one of its constituent parts compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 , obo:WBPhenotype_0000656 , obo:WBPhenotype_0001833 .
obo:GO_0040007 a rdfs:Class ;
rdfs:label "growth" ;
rdfs:comment "The increase in size or mass of an entire organism, a part of an organism or a cell." ;
rdfs:subClassOf obo:GO_0008150 .
obo:WBPhenotype_0001763 a rdfs:Class ;
rdfs:label "uptake by intestinal cell defective" ;
rdfs:comment "Uptake of subtances from the intestine is altered from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000986 .
obo:WBPhenotype_0000654 a rdfs:Class ;
rdfs:label "synaptic vesicle exocytosis variant" ;
rdfs:comment "Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000728 , obo:WBPhenotype_0001684 .
obo:GO_1905819 a rdfs:Class ;
rdfs:label "negative regulation of chromosome separation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation." ;
rdfs:subClassOf obo:GO_0051985 , obo:GO_0065007 , obo:GO_1905818 .
obo:GO_0051047 a rdfs:Class ;
rdfs:label "positive regulation of secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ;
rdfs:subClassOf obo:GO_0051046 , obo:GO_0051050 , obo:GO_0065007 .
obo:GO_0098813 a rdfs:Class ;
rdfs:label "nuclear chromosome segregation" ;
rdfs:comment "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." ;
rdfs:subClassOf obo:GO_0007059 .
obo:GO_0030424 a rdfs:Class ;
rdfs:label "axon" ;
rdfs:comment "The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter." ;
rdfs:subClassOf obo:GO_0043005 .
obo:GO_0021700 a rdfs:Class ;
rdfs:label "developmental maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0032502 .
obo:PATO_0103000 a rdfs:Class ;
rdfs:label "quantitative" ;
rdfs:comment "A quality of an entity that can be represented numerically, including anything that can be counted, measured, or given a numerical value." ;
rdfs:subClassOf obo:PATO_0000001 .
obo:WBPhenotype_0001220 a rdfs:Class ;
rdfs:label "cell death sexually dimorphic increased" ;
rdfs:comment "Animals exhibit in increase in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations." ;
rdfs:subClassOf obo:WBPhenotype_0001218 .
obo:WBPhenotype_0002355 a rdfs:Class ;
rdfs:label "increased susceptibility to bacterial pathogens" ;
rdfs:comment "Animals are more prone to infection by bacterial pathogens compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001013 , obo:WBPhenotype_0002545 .
obo:CHEBI_76832 a rdfs:Class ;
rdfs:label "EC 4.3.1.* (ammonia-lyase) inhibitor" ;
rdfs:comment "An EC 4.3.* (C‒N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*)." ;
rdfs:subClassOf obo:CHEBI_76713 .
obo:GO_0071480 a rdfs:Class ;
rdfs:label "cellular response to gamma radiation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum." ;
rdfs:subClassOf obo:GO_0010332 , obo:GO_0071479 .
obo:CHEBI_68495 a rdfs:Class ;
rdfs:label "apoptosis inducer" ;
rdfs:comment "Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms." ;
rdfs:subClassOf obo:CHEBI_52206 .
obo:WBPhenotype_0001182 a rdfs:Class ;
rdfs:label "fat content variant" ;
rdfs:comment "Animals exhibit variations in the amount of fat or lipids present in the organism compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000725 .
obo:WBPhenotype_0002102 a rdfs:Class ;
rdfs:label "golgi apparatus localization variant" ;
rdfs:comment "Any variation in the subcellular localization of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002098 .
obo:CHEBI_26214 a rdfs:Class ;
rdfs:label "porphyrins" ;
rdfs:comment "Natural pigments containing a fundamental skeleton of four pyrrole nuclei united through the α-positions by four methine groups to form a macrocyclic structure." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_36309 .
obo:PATO_0000117 a rdfs:Class ;
rdfs:label "size" ;
rdfs:comment "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:CHEBI_26816 a rdfs:Class ;
rdfs:label "carbohydrate phosphate" ;
rdfs:subClassOf obo:CHEBI_25703 , obo:CHEBI_37734 , obo:CHEBI_63299 .
obo:WBPhenotype_0001994 a rdfs:Class ;
rdfs:label "left right handedness variant" ;
rdfs:comment "Any variation in the establishment of left-right asymmetry of the body axis compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000578 .
obo:WBPhenotype_0002333 a rdfs:Class ;
rdfs:label "track length increased" ;
rdfs:comment "Animals exhibit increased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope." ;
rdfs:subClassOf obo:WBPhenotype_0002332 .
obo:GO_0051984 a rdfs:Class ;
rdfs:label "positive regulation of chromosome segregation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ;
rdfs:subClassOf obo:GO_0051983 , obo:GO_0065007 , obo:GO_0090068 .
obo:GO_0006909 a rdfs:Class ;
rdfs:label "phagocytosis" ;
rdfs:comment "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." ;
rdfs:subClassOf obo:GO_0006897 .
obo:CHEBI_36587 a rdfs:Class ;
rdfs:label "organic oxo compound" ;
rdfs:comment "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." ;
rdfs:subClassOf obo:CHEBI_72695 .
obo:GO_0042053 a rdfs:Class ;
rdfs:label "regulation of dopamine metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ;
rdfs:subClassOf obo:GO_0042069 , obo:GO_0065007 .
obo:WBPhenotype_0001358 a rdfs:Class ;
rdfs:label "male nervous system morphology variant" ;
rdfs:comment "Male animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000604 , obo:WBPhenotype_0001024 .
obo:WBPhenotype_0002328 a rdfs:Class ;
rdfs:label "amplitude of sinusoidal movement increased" ;
rdfs:comment "Animals exhibit an increase in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0004022 .
obo:CHEBI_52208 a rdfs:Class ;
rdfs:label "biophysical role" ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:WBPhenotype_0001311 a rdfs:Class ;
rdfs:label "protein expression reduced hermaphrodite" ;
rdfs:comment "Variations that result in a decrease in protein expression in hermaphrodites compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000120 .
obo:WBPhenotype_0000520 a rdfs:Class ;
rdfs:label "morphology phenotype" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any of its parts compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002551 .
obo:GO_0048869 a rdfs:Class ;
rdfs:label "cellular developmental process" ;
rdfs:comment "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0032502 .
obo:GO_1902513 a rdfs:Class ;
rdfs:label "regulation of organelle transport along microtubule" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of organelle transport along microtubule." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0060632 , obo:GO_0065007 .
obo:GO_0048640 a rdfs:Class ;
rdfs:label "negative regulation of developmental growth" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." ;
rdfs:subClassOf obo:GO_0045926 , obo:GO_0048638 , obo:GO_0051093 , obo:GO_0065007 .
obo:GO_2000104 a rdfs:Class ;
rdfs:label "negative regulation of DNA-templated DNA replication" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication." ;
rdfs:subClassOf obo:GO_0008156 , obo:GO_0065007 , obo:GO_0090329 .
obo:CHEBI_76414 a rdfs:Class ;
rdfs:label "propellant" ;
rdfs:comment "A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:CHEBI_35441 a rdfs:Class ;
rdfs:label "antiinfective agent" ;
rdfs:comment "A substance used in the prophylaxis or therapy of infectious diseases." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0034609 a rdfs:Class ;
rdfs:label "spicule insertion" ;
rdfs:comment "Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva." ;
rdfs:subClassOf obo:GO_0060179 .
obo:WBPhenotype_0002609 a rdfs:Class ;
rdfs:label "hammerhead"@en ;
rdfs:comment "An anterior enclosure defect in which the anterior portion of the embryo, unenclosed by the hypodermis, bulges to form a hammerhead shape." ;
rdfs:subClassOf obo:WBPhenotype_0002571 .
obo:WBPhenotype_0002483 a rdfs:Class ;
rdfs:label "fungal resistance increased" ;
rdfs:comment "Animals are less prone to infection by a fungus compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001014 .
obo:WBPhenotype_0002029 a rdfs:Class ;
rdfs:label "metal homeostasis variant" ;
rdfs:comment "Variations in the regulation of levels, transport, and metabolism of metal ions within an organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:GO_0001705 a rdfs:Class ;
rdfs:label "ectoderm formation" ;
rdfs:comment "The formation of ectoderm during gastrulation." ;
rdfs:subClassOf obo:GO_0001704 .
obo:WBPhenotype_0002249 a rdfs:Class ;
rdfs:label "reduced protein oxidation levels" ;
rdfs:comment "Protein oxidation levels, as measured by carbonylated protein levels for example, are reduced compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000068 .
obo:WBPhenotype_0000193 a rdfs:Class ;
rdfs:label "dominant negative enzyme" ;
rdfs:comment "Any variation within an enzyme that causes it to act antagonistically towards the wild-type enzymatic product. These mutations usually result in an altered molecular function (often inactive) and are characterized by a dominant or semi-dominant phenotype." ;
rdfs:subClassOf obo:WBPhenotype_0000727 .
obo:GO_0036276 a rdfs:Class ;
rdfs:label "response to antidepressant" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug." ;
rdfs:subClassOf obo:GO_0042221 .
obo:PATO_0000586 a rdfs:Class ;
rdfs:label "increased size" ;
rdfs:comment "A size quality which is relatively high." ;
rdfs:subClassOf obo:PATO_0000117 , obo:PATO_0002305 .
obo:GO_0042430 a rdfs:Class ;
rdfs:label "indole-containing compound metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0048523 a rdfs:Class ;
rdfs:label "negative regulation of cellular process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0001723 a rdfs:Class ;
rdfs:label "pathogen infected pharynx decrease" ;
rdfs:comment "Animals exhibit a lesser extent of pathogen invasion into the pharynx compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001721 .
obo:WBPhenotype_0002582 a rdfs:Class ;
rdfs:label "miniature inhibitory post-synaptic current phenotype"@en ;
rdfs:comment "Animals exhibit variations in miniature inhibitory post-synaptic currents (mIPSC), compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002014 .
obo:GO_1903465 a rdfs:Class ;
rdfs:label "positive regulation of mitotic cell cycle DNA replication" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication." ;
rdfs:subClassOf obo:GO_0010571 , obo:GO_0045931 , obo:GO_0065007 , obo:GO_1903463 .
obo:WBbt_0005754 a rdfs:Class ;
rdfs:label "interfacial epithelial cell" ;
rdfs:comment "an epithelial cell that serves either to bridge two neighboring epithelial tissues or to form an opening in the epithelium." ;
rdfs:subClassOf obo:WBbt_0003672 .
obo:GO_0000781 a rdfs:Class ;
rdfs:label "chromosome, telomeric region" ;
rdfs:comment "The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres)." ;
rdfs:subClassOf obo:GO_0098687 .
obo:WBPhenotype_0002371 a rdfs:Class ;
rdfs:label "vesicle maturation defective" ;
rdfs:comment "Vesicles, including those in cells, cell bodies, or synaptic terminals, do not properly form or maintain an intermediate state, such as remain coated with a clathrin coat." ;
rdfs:subClassOf obo:WBPhenotype_0001321 .
obo:GO_0104004 a rdfs:Class ;
rdfs:label "cellular response to environmental stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus." ;
rdfs:subClassOf obo:GO_0051716 .
obo:WBPhenotype_0004029 a rdfs:Class ;
rdfs:label "sexually dimorphic mechanosensation variant" ;
rdfs:comment "Any variation with respect to perception or response to mechanical stimuli in a sex dependent manner compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:CHEBI_25512 a rdfs:Class ;
rdfs:label "neurotransmitter" ;
rdfs:comment "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." ;
rdfs:subClassOf obo:CHEBI_33280 .
obo:CHEBI_36982 a rdfs:Class ;
rdfs:label "cyclic purine nucleotide" ;
rdfs:subClassOf obo:CHEBI_23447 , obo:CHEBI_26395 .
obo:PATO_0000592 a rdfs:Class ;
rdfs:label "decreased thickness" ;
rdfs:comment "A thickness which is relatively low." ;
rdfs:subClassOf obo:PATO_0000587 , obo:PATO_0000915 .
obo:WBPhenotype_0002148 a rdfs:Class ;
rdfs:label "somatic RNAi resistant" ;
rdfs:comment "Animals show reduced susceptibility to gene silencing in somatic cells triggered by double stranded RNA (dsRNA), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001208 .
obo:GO_1902805 a rdfs:Class ;
rdfs:label "positive regulation of synaptic vesicle transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0051050 , obo:GO_0065007 , obo:GO_1902803 .
obo:GO_1901190 a rdfs:Class ;
rdfs:label "regulation of formation of translation initiation ternary complex" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0065007 .
obo:WBPhenotype_0001171 a rdfs:Class ;
rdfs:label "shortened life span" ;
rdfs:comment "The duration of viability in the adult phase of the life-cycle is less than that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000039 .
obo:WBPhenotype_0000877 a rdfs:Class ;
rdfs:label "amphid sheath cell development variant" ;
rdfs:comment "Any variation in the progression of a sheath cell of the amphid sensillum over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000950 .
obo:WBPhenotype_0000137 a rdfs:Class ;
rdfs:label "mRNA levels reduced" ;
rdfs:comment "Animals exhibit decreased levels of messenger RNA compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000114 .
obo:WBPhenotype_0001564 a rdfs:Class ;
rdfs:label "duration of self fertility variant" ;
rdfs:comment "The window of production of self-fertilized eggs exceeds or does not extend to the same length as control." ;
rdfs:subClassOf obo:WBPhenotype_0000806 .
obo:CHEBI_39745 a rdfs:Class ;
rdfs:label "dihydrogenphosphate" ;
rdfs:comment "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." ;
rdfs:subClassOf obo:CHEBI_35780 , obo:CHEBI_79389 .
obo:GO_0000084 a rdfs:Class ;
rdfs:label "mitotic S phase" ;
rdfs:comment "The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0051320 .
obo:GO_0010557 a rdfs:Class ;
rdfs:label "positive regulation of macromolecule biosynthetic process" ;
rdfs:comment "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0010556 , obo:GO_0010604 , obo:GO_0065007 .
obo:WBPhenotype_0002358 a rdfs:Class ;
rdfs:label "transdifferentiation defective" ;
rdfs:comment "The conversion of one differentiated cell type into another does not occur as it does in control animals. In C. elegans, the Y cell undergoes a dramatic redifferentiation from being a cell in of the rectum to a PDA neuron. This transdifferentiation requires the cell to withdraw from its established position, migrate, and then become a motor neuron." ;
rdfs:subClassOf obo:WBPhenotype_0001510 .
obo:WBPhenotype_0001942 a rdfs:Class ;
rdfs:label "rachis absent" ;
rdfs:comment "The nucleus-free core of germline cytoplasm in the gonad is missing." ;
rdfs:subClassOf obo:WBPhenotype_0001940 .
obo:GO_0002683 a rdfs:Class ;
rdfs:label "negative regulation of immune system process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0048519 , obo:GO_0065007 .
obo:WBPhenotype_0000831 a rdfs:Class ;
rdfs:label "Y lineage variant" ;
rdfs:comment "The descendants of the Y cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000809 .
obo:WBPhenotype_0001538 a rdfs:Class ;
rdfs:label "mRNA surveillance defective" ;
rdfs:comment "Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia." ;
rdfs:subClassOf obo:WBPhenotype_0000028 .
obo:CHEBI_231930 a rdfs:Class ;
rdfs:label "pent-2-enoate" ;
rdfs:comment "A pentenoate having the double bond at the 2-position." ;
rdfs:subClassOf obo:CHEBI_36030 .
obo:CHEBI_35703 a rdfs:Class ;
rdfs:label "xenobiotic" ;
rdfs:comment "A xenobiotic (Greek, xenos \"foreign\"; bios \"life\") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:WBPhenotype_0002312 a rdfs:Class ;
rdfs:label "turning frequency variant" ;
rdfs:comment "Animals exhibit variations in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." ;
rdfs:subClassOf obo:WBPhenotype_0002311 .
obo:WBbt_0005098 a rdfs:Class ;
rdfs:label "lumbar ganglion left" ;
rdfs:comment "lumbar ganglion, left side." ;
rdfs:subClassOf obo:WBbt_0005830 .
obo:WBPhenotype_0002322 a rdfs:Class ;
rdfs:label "forward point velocity increased" ;
rdfs:comment "Animals exhibit increased velocity of forward translocation of any point along the animal's track from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001716 .
obo:GO_0030990 a rdfs:Class ;
rdfs:label "intraciliary transport particle" ;
rdfs:comment "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." ;
rdfs:subClassOf obo:GO_0032991 .
obo:WBPhenotype_0001657 a rdfs:Class ;
rdfs:label "cell junction variant" ;
rdfs:comment "Animals exhibit variations in the specialized region of connection between two cells or between a cell and the extracellular matrix compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001399 .
obo:CHEBI_62488 a rdfs:Class ;
rdfs:label "signalling molecule" ;
rdfs:comment "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell." ;
rdfs:subClassOf obo:CHEBI_33280 .
obo:CHEBI_45379 a rdfs:Class ;
rdfs:label "methylcarbamic acid" ;
rdfs:comment "An amino acid consisting of carbamic acid having an N-methyl substituent." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:WBPhenotype_0000227 a rdfs:Class ;
rdfs:label "male turning defective" ;
rdfs:comment "The inability of a male to properly turn during mating behavior. In C. elegans, males typically turn via a sharp ventral arch of the tail, as he approaches either the hermaphrodite head or tail." ;
rdfs:subClassOf obo:WBPhenotype_0004006 .
obo:GO_0007586 a rdfs:Class ;
rdfs:label "digestion" ;
rdfs:comment "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0032501 .
obo:WBPhenotype_0000182 a rdfs:Class ;
rdfs:label "apoptosis reduced" ;
rdfs:comment "Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000730 , obo:WBPhenotype_0002620 .
obo:WBPhenotype_0000614 a rdfs:Class ;
rdfs:label "GLR development variant" ;
rdfs:comment "Any variation in the progression of the GLR accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000942 .
obo:CHEBI_35480 a rdfs:Class ;
rdfs:label "analgesic" ;
rdfs:comment "An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_52210 .
obo:CHEBI_25255 a rdfs:Class ;
rdfs:label "methyl methanesulfonate" ;
rdfs:comment "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25223 .
obo:GO_0048639 a rdfs:Class ;
rdfs:label "positive regulation of developmental growth" ;
rdfs:comment "Any process that activates, maintains or increases the rate of developmental growth." ;
rdfs:subClassOf obo:GO_0045927 , obo:GO_0048638 , obo:GO_0051094 , obo:GO_0065007 .
obo:WBPhenotype_0001343 a rdfs:Class ;
rdfs:label "meiotic spindle defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a meiotic cell cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000759 , obo:WBPhenotype_0001868 .
obo:WBPhenotype_0002415 a rdfs:Class ;
rdfs:label "spindle assembly defective" ;
rdfs:comment "Cells exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ;
rdfs:subClassOf obo:WBPhenotype_0002414 .
obo:WBPhenotype_0001857 a rdfs:Class ;
rdfs:label "pathogen induced gene expression variant" ;
rdfs:comment "Gene expression of an animal is not influenced by the exposure to disease causing agents in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000717 , obo:WBPhenotype_0001012 .
obo:CHEBI_16199 a rdfs:Class ;
rdfs:label "urea" ;
rdfs:comment "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O)." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_29347 , obo:CHEBI_64708 .
obo:WBPhenotype_0001166 a rdfs:Class ;
rdfs:label "excess paternal pronucleus variant centrosome early emb" ;
rdfs:comment "More than one paternal pronucleus is present in the inviable one-cell embryo or there is a defect in centrosome structure." ;
rdfs:subClassOf obo:WBPhenotype_0001164 .
obo:GO_0035770 a rdfs:Class ;
rdfs:label "ribonucleoprotein granule" ;
rdfs:comment "A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions." ;
rdfs:subClassOf obo:GO_0043232 , obo:GO_0099080 .
obo:WBPhenotype_0000805 a rdfs:Class ;
rdfs:label "tail development variant" ;
rdfs:comment "Any variation in the process whose specific outcome is the progression of the tail over time, from its formation to the mature structure, compared to control. The tail includes the posterior region that spans from the rectum to the end." ;
rdfs:subClassOf obo:WBPhenotype_0000528 , obo:WBPhenotype_0000579 .
obo:PATO_0001810 a rdfs:Class ;
rdfs:label "wrinkled" ;
rdfs:comment "A grooved texture quality inhering in a bearer by virtue of the bearer's being marked by one or more creases in a normally smooth surface." ;
rdfs:subClassOf obo:PATO_0002255 .
obo:WBPhenotype_0001127 a rdfs:Class ;
rdfs:label "EMS anterior extension fails early emb" ;
rdfs:comment "The EMS blastomere fails to extend anteriorly and make extensive contact (hug) with the ABa blastomere." ;
rdfs:subClassOf obo:WBPhenotype_0001118 .
obo:WBPhenotype_0000150 a rdfs:Class ;
rdfs:label "starvation induced dauer formation defective" ;
rdfs:comment "Animals do not enter dauer under nutrient-poor conditions that induce dauer formation in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000013 , obo:WBPhenotype_0000148 .
obo:CHEBI_28112 a rdfs:Class ;
rdfs:label "nickel atom" ;
rdfs:comment "Chemical element (nickel group element atom) with atomic number 28." ;
rdfs:subClassOf obo:CHEBI_33362 , obo:CHEBI_88184 .
obo:WBPhenotype_0001914 a rdfs:Class ;
rdfs:label "fewer pharyngeal cells" ;
rdfs:comment "Animals contain fewer pharyngeal cells compared to control animals. In C. elegans, pharyngeal cells are derived from MS-blastomere." ;
rdfs:subClassOf obo:WBPhenotype_0000707 , obo:WBPhenotype_0002174 .
obo:CHEBI_15318 a rdfs:Class ;
rdfs:label "xanthine" ;
rdfs:comment "A purine nucleobase found in humans and other organisms." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25810 , obo:CHEBI_26386 .
obo:WBPhenotype_0000041 a rdfs:Class ;
rdfs:label "osmotic integrity variant" ;
rdfs:comment "Any variation in the process involved in the maintenance of an internal equilibrium of water within an organism, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:GO_0045595 a rdfs:Class ;
rdfs:label "regulation of cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0050794 , obo:GO_0065007 .
obo:CHEBI_64250 a rdfs:Class ;
rdfs:label "tunicamycin B2" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 13-methyltetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:CL_0000064 a rdfs:Class ;
rdfs:label "ciliated cell" ;
rdfs:comment "A cell that has a filiform extrusion of the cell surface." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:WBPhenotype_0001983 a rdfs:Class ;
rdfs:label "lawn leaving behavior variant" ;
rdfs:comment "Variation of the time an individual spent on a patch of food (bacterial lawn) before leaving, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000662 .
obo:GO_1902584 a rdfs:Class ;
rdfs:label "positive regulation of response to water deprivation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of response to water deprivation." ;
rdfs:subClassOf obo:GO_0048584 , obo:GO_0065007 , obo:GO_2000070 .
obo:CHEBI_26036 a rdfs:Class ;
rdfs:label "phosphatidylinositol monophosphate" ;
rdfs:subClassOf obo:CHEBI_28765 .
obo:WBPhenotype_0002543 a rdfs:Class ;
rdfs:label "spontaneous mitochondrial DNA mutation rate increased"@en ;
rdfs:comment "Animals accumulate a greater number of mitochondrial genetic lesions than control animals in the absence of an externally controlled mutagen." ;
rdfs:subClassOf obo:WBPhenotype_0000228 .
obo:GO_0042428 a rdfs:Class ;
rdfs:label "serotonin metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ;
rdfs:subClassOf obo:GO_0018958 , obo:GO_0042430 .
obo:CHEBI_26191 a rdfs:Class ;
rdfs:label "polyol" ;
rdfs:comment "A compound that contains two or more hydroxy groups." ;
rdfs:subClassOf obo:CHEBI_33822 .
obo:WBPhenotype_0000323 a rdfs:Class ;
rdfs:label "head swollen" ;
rdfs:comment "The most anterior portion of the animal appears bloated or distended." ;
rdfs:subClassOf obo:WBPhenotype_0000071 .
obo:CHEBI_33576 a rdfs:Class ;
rdfs:label "sulfur-containing carboxylic acid" ;
rdfs:comment "Any carboxylic acid having a sulfur substituent." ;
rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_33575 .
obo:GO_0048026 a rdfs:Class ;
rdfs:label "positive regulation of mRNA splicing, via spliceosome" ;
rdfs:comment "Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism." ;
rdfs:subClassOf obo:GO_0033120 , obo:GO_0048024 , obo:GO_0050685 , obo:GO_0065007 .
obo:WBPhenotype_0001300 a rdfs:Class ;
rdfs:label "germ cell cytoplasmic morphology variant" ;
rdfs:comment "Any variation in the composition or structure of the contents within a germ cell, excluding the plasma membrane and nucleus, compared to control. Germ cells include sperm, oocytes, and their precursors." ;
rdfs:subClassOf obo:WBPhenotype_0000900 , obo:WBPhenotype_0002089 .
obo:PATO_0000078 a rdfs:Class ;
rdfs:label "rhythm quality" ;
rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's movement or variation characterized by the regular recurrence or alternation of different quantities or conditions." ;
rdfs:subClassOf obo:PATO_0002323 .
obo:WBPhenotype_0000096 a rdfs:Class ;
rdfs:label "cloacal development variant" ;
rdfs:comment "Variations in the progression of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) over time compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000617 , obo:WBPhenotype_0000930 .
obo:CHEBI_22315 a rdfs:Class ;
rdfs:label "alkaloid" ;
rdfs:comment "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35352 .
obo:WBPhenotype_0000450 a rdfs:Class ;
rdfs:label "obsolete swollen male tail" ;
rdfs:comment "OBSOLETE." .
obo:GO_0048584 a rdfs:Class ;
rdfs:label "positive regulation of response to stimulus" ;
rdfs:comment "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0048583 , obo:GO_0065007 .
obo:GO_2000019 a rdfs:Class ;
rdfs:label "negative regulation of male gonad development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905940 , obo:GO_2000018 .
obo:WBPhenotype_0000937 a rdfs:Class ;
rdfs:label "W lineage variant" ;
rdfs:comment "The descendants of the W precursor cell exhibit any variation in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000825 .
obo:WBPhenotype_0000104 a rdfs:Class ;
rdfs:label "cell polarity variant" ;
rdfs:comment "Contents or structures of a cell are no longer restricted/localized to their typical positions within the cell." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:CHEBI_33482 a rdfs:Class ;
rdfs:label "sulfur oxoanion" ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_33485 .
obo:GO_0006468 a rdfs:Class ;
rdfs:label "protein phosphorylation" ;
rdfs:comment "The process of introducing a phosphate group on to a protein." ;
rdfs:subClassOf obo:GO_0016310 , obo:GO_0036211 .
obo:WBPhenotype_0002199 a rdfs:Class ;
rdfs:label "neuron calcium transient levels variant" ;
rdfs:comment "The degree of stimulus-evoked calcium concentration changes differs from that of controls." ;
rdfs:subClassOf obo:WBPhenotype_0002563 .
obo:WBPhenotype_0000364 a rdfs:Class ;
rdfs:label "gut granule birefringence misplaced" ;
rdfs:comment "The birefringent inclusions typically found in the intestinal cytoplasm accumulate extracellularly in the intestinal lumen." ;
rdfs:subClassOf obo:WBPhenotype_0002240 .
obo:WBPhenotype_0001133 a rdfs:Class ;
rdfs:label "division axis defective" ;
rdfs:comment "The cell division axis is not normal." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:WBPhenotype_0000866 a rdfs:Class ;
rdfs:label "germ cell arrest" ;
rdfs:comment "Germ cells fail to undergo meiotic differentiation to form mature gametes." ;
rdfs:subClassOf obo:WBPhenotype_0000823 .
obo:WBbt_0003734 a rdfs:Class ;
rdfs:label "isthmus" ;
rdfs:comment "a section of pharynx of which muscles contract with a peristaltic motion." ;
rdfs:subClassOf obo:WBbt_0005789 .
obo:WBPhenotype_0001954 a rdfs:Class ;
rdfs:label "diplotene absent during oogenesis" ;
rdfs:comment "The diplotene stage is not observed in developing oocytes. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." ;
rdfs:subClassOf obo:WBPhenotype_0001947 .
obo:PATO_0001018 a rdfs:Class ;
rdfs:label "physical quality" ;
rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:WBPhenotype_0001173 a rdfs:Class ;
rdfs:label "non apoptotic cell death variant" ;
rdfs:comment "Animals exhibit variations in the specific activation or halting of processes within a cell that occur through necrosis or programmed cell death pathways different from apoptosis, so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001172 .
obo:WBPhenotype_0000820 a rdfs:Class ;
rdfs:label "embryonic behavior variant" ;
rdfs:comment "Activity characteristic of an embryo is altered compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001000 .
obo:WBPhenotype_0002095 a rdfs:Class ;
rdfs:label "lysosome-related organelle morphology variant" ;
rdfs:comment "Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002089 .
obo:WBPhenotype_0000483 a rdfs:Class ;
rdfs:label "no gut granules" ;
rdfs:comment "Animals lack the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000103 .
obo:WBPhenotype_0001000 a rdfs:Class ;
rdfs:label "developmental behavior variant" ;
rdfs:comment "Any variation in the behavior characteristic during certain developmental stage(s) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:WBPhenotype_0001931 a rdfs:Class ;
rdfs:label "muscle arm axon connection variant" ;
rdfs:comment "The morphology or number of connections between muscle arms and commissural motor axons varies from control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000540 .
obo:WBPhenotype_0002628 a rdfs:Class ;
rdfs:label "in vitro attachment to substrate reduced"@en ;
rdfs:comment "Animals exhibit a reduced attachment to a substrate in vitro, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002627 .
obo:WBPhenotype_0002508 a rdfs:Class ;
rdfs:label "extra neuron"@en ;
rdfs:comment "Animals produce an excess number of neurons compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002175 .
obo:WBPhenotype_0001480 a rdfs:Class ;
rdfs:label "grinder relaxation variant" ;
rdfs:comment "Variations in the rhythmic relaxations of the a highly specialized cuticle region of the pharynx inside the lumen of the second bulb, compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000336 .
obo:GO_0090325 a rdfs:Class ;
rdfs:label "regulation of locomotion involved in locomotory behavior" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ;
rdfs:subClassOf obo:GO_0040012 , obo:GO_0050795 , obo:GO_0065007 .
obo:PATO_0001309 a rdfs:Class ;
rdfs:label "duration" ;
rdfs:comment "A process quality inhering in a bearer by virtue of the bearer's magnitude of the temporal extent between the starting and ending point." ;
rdfs:subClassOf obo:PATO_0002062 .
obo:GO_0051590 a rdfs:Class ;
rdfs:label "positive regulation of neurotransmitter transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051050 , obo:GO_0051588 , obo:GO_0065007 .
obo:GO_0033059 a rdfs:Class ;
rdfs:label "cellular pigmentation" ;
rdfs:comment "The deposition or aggregation of coloring matter in a cell." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0043473 .
obo:CHEBI_33695 a rdfs:Class ;
rdfs:label "information biomacromolecule" ;
rdfs:subClassOf obo:CHEBI_33694 .
obo:WBPhenotype_0001150 a rdfs:Class ;
rdfs:label "polar body reabsorbed one two early emb" ;
rdfs:comment "A polar body is reabsorbed in either the one cell- or the two-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001148 .
obo:WBPhenotype_0002404 a rdfs:Class ;
rdfs:label "cell cell contacts abnormal" ;
rdfs:comment "Cell-cell contacts are abnormal, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000533 .
obo:GO_0034329 a rdfs:Class ;
rdfs:label "cell junction assembly" ;
rdfs:comment "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0034330 .
obo:CHEBI_17790 a rdfs:Class ;
rdfs:label "methanol" ;
rdfs:comment "The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_134179 , obo:CHEBI_15734 , obo:CHEBI_50584 , obo:CHEBI_64708 .
obo:WBPhenotype_0002589 a rdfs:Class ;
rdfs:label "neuron degeneration reduced"@en ;
rdfs:comment "Animals exhibit a reduction in neuron degeneration, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000636 .
obo:WBPhenotype_0000234 a rdfs:Class ;
rdfs:label "dopamine deficient" ;
rdfs:comment "Animals do not contain or are unable to maintain a the level of dopamine capable of initiating or maintaining dopamine-dependent cell activity compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000233 .
obo:WBPhenotype_0000490 a rdfs:Class ;
rdfs:label "pharynx disorganized" ;
rdfs:comment "The components of the feeding organ fail to be arranged in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000707 .
obo:CHEBI_37176 a rdfs:Class ;
rdfs:label "mononuclear parent hydride" ;
rdfs:subClassOf obo:CHEBI_33692 .
obo:CHEBI_30985 a rdfs:Class ;
rdfs:label "4,4'-bipyridine" ;
rdfs:comment "A bipyridine in which the two pyridine moieties are linked by a bond between positions C-4 and C-4'." ;
rdfs:subClassOf obo:CHEBI_35545 .
obo:CHEBI_35939 a rdfs:Class ;
rdfs:label "pent-2-enoic acid" ;
rdfs:comment "A pentenoic acid having the double bond at position 2." ;
rdfs:subClassOf obo:CHEBI_25897 , obo:CHEBI_79020 .
obo:WBPhenotype_0002057 a rdfs:Class ;
rdfs:label "Bacillus thuringiensis toxin hypersensitive" ;
rdfs:comment "Animals respond to Bacillus thuringiensis toxins (Bt toxins) at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 .
obo:WBPhenotype_0001943 a rdfs:Class ;
rdfs:label "rachis wide" ;
rdfs:comment "The width of the nucleus-free core of germline cytoplasm in the gonad is larger compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001940 .
obo:CHEBI_22984 a rdfs:Class ;
rdfs:label "calcium atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_22313 .
obo:GO_0051129 a rdfs:Class ;
rdfs:label "negative regulation of cellular component organization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0051128 , obo:GO_0065007 .
obo:CHEBI_33595 a rdfs:Class ;
rdfs:label "cyclic compound" ;
rdfs:comment "Any molecule that consists of a series of atoms joined together to form a ring." ;
rdfs:subClassOf obo:CHEBI_25367 .
obo:CHEBI_63941 a rdfs:Class ;
rdfs:label "22,23-dihydroavermectin B1a" ;
rdfs:comment "A macrocyclic lactone that is avermectin B1a in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the major component of ivermectin." ;
rdfs:subClassOf obo:CHEBI_63944 , obo:CHEBI_72600 .
obo:GO_0040011 a rdfs:Class ;
rdfs:label "locomotion" ;
rdfs:comment "Self-propelled movement of a cell or organism from one location to another." ;
rdfs:subClassOf obo:GO_0008150 .
obo:WBPhenotype_0001514 a rdfs:Class ;
rdfs:label "synaptic vesicle endocytosis variant" ;
rdfs:comment "Variations in the uptake of a small membrane-bound organelle, filled with neurotransmitter(s) and/or neuropeptides, by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle compared to control(Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001422 , obo:WBPhenotype_0001684 .
obo:WBPhenotype_0001503 a rdfs:Class ;
rdfs:label "ventral nerve cord maintenance variant" ;
rdfs:comment "Any variation in the mechanisms used to ensure that axons in the ventral nerve cord maintain their correct positioning after termination of axonal outgrowth and target recognition compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000515 .
obo:WBPhenotype_0000375 a rdfs:Class ;
rdfs:label "later divisions prolonged" ;
rdfs:comment "The time interval in which late embryonic cell divisions occur is increased compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:GO_1902315 a rdfs:Class ;
rdfs:label "nuclear cell cycle DNA replication initiation" ;
rdfs:comment "Any DNA replication initiation that is involved in nuclear cell cycle DNA replication." ;
rdfs:subClassOf obo:GO_0006270 , obo:GO_1902292 .
obo:WBPhenotype_0001437 a rdfs:Class ;
rdfs:label "octanol chemotaxis hypersensitive" ;
rdfs:comment "Animals execute a response, via directed movement to octanol at a lower concentration or shorter exposure time compared to control. In C. elegans, animals avoid octanol." ;
rdfs:subClassOf obo:WBPhenotype_0001452 .
obo:WBPhenotype_0002188 a rdfs:Class ;
rdfs:label "male somatic gonad development variant" ;
rdfs:comment "Any variation in the progression of the components of the male gonad that are separate from the germline proper over time, from its formation to its mature structure compared to control. In C. elegans, the male somatic gonad consists of three tissues: distal tip cells (DTCs), the seminal vesicle, and the vas deferens (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000399 , obo:WBPhenotype_0001675 .
obo:WBbt_0006908 a rdfs:Class ;
rdfs:label "gubernacular muscle" ;
rdfs:comment "specialized muscle type in male sex organ." ;
rdfs:subClassOf obo:WBbt_0005757 , obo:WBbt_0005780 , obo:WBbt_0007810 .
obo:CHEBI_26151 a rdfs:Class ;
rdfs:label "piperidines" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:WBls_0000105 a rdfs:Class ;
rdfs:label "nematode larval stage" ;
rdfs:comment "The stage that begins after hatching and ends when the nematode becomes adult." ;
rdfs:subClassOf obo:WBls_0000101 .
obo:GO_0045161 a rdfs:Class ;
rdfs:label "neuronal ion channel clustering" ;
rdfs:comment "The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation." ;
rdfs:subClassOf obo:GO_0061024 .
obo:GO_0008283 a rdfs:Class ;
rdfs:label "cell population proliferation" ;
rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a cell population." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0000010 a rdfs:Class ;
rdfs:label "drug hypersensitive" ;
rdfs:comment "Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:PATO_0000628 a rdfs:Class ;
rdfs:label "mislocalised" ;
rdfs:comment "A positional quality inhering in a bearer by virtue the bearer's being changed in abnormal position." ;
rdfs:subClassOf obo:PATO_0002181 .
obo:GO_0045934 a rdfs:Class ;
rdfs:label "negative regulation of nucleobase-containing compound metabolic process" ;
rdfs:comment "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0019219 , obo:GO_0065007 .
obo:GO_0007610 a rdfs:Class ;
rdfs:label "behavior" ;
rdfs:comment "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." ;
rdfs:subClassOf obo:GO_0032501 .
obo:WBPhenotype_0000205 a rdfs:Class ;
rdfs:label "expulsion variant" ;
rdfs:comment "Any variation in the expulsion of gut contents compared to control. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion." ;
rdfs:subClassOf obo:WBPhenotype_0000210 .
obo:WBPhenotype_0001026 a rdfs:Class ;
rdfs:label "nuclear morphology variation early emb" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of the membrane enclosed organelle which contains most of the cell's genetic material during the early embryonic stage compared to control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001028 , obo:WBPhenotype_0001035 .
obo:PATO_0000017 a rdfs:Class ;
rdfs:label "color saturation" ;
rdfs:comment "A scalar chromatic property that is the degree of purity of perceived light." ;
rdfs:subClassOf obo:PATO_0001301 .
obo:WBPhenotype_0002596 a rdfs:Class ;
rdfs:label "sleep deprivation-induced brood size reduction suppressed"@en ;
rdfs:comment "The reduction in brood size caused by sleep deprivation is suppressed, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000154 .
obo:GO_0060090 a rdfs:Class ;
rdfs:label "molecular adaptor activity" ;
rdfs:comment "The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way." ;
rdfs:subClassOf obo:GO_0003674 .
obo:WBPhenotype_0001907 a rdfs:Class ;
rdfs:label "dorsal intercalation defective" ;
rdfs:comment "Animals exhibit defects in the generation of the dorsal epithelial sheet, which entails distinct cell shape changes and movements to affect the interdigitation of two rows of dorsal cells resulting in a single row of cells across the dorsal midline." ;
rdfs:subClassOf obo:WBPhenotype_0002569 .
obo:WBPhenotype_0000974 a rdfs:Class ;
rdfs:label "accessory cell physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required by a subset of interfacial cells to carry out its normal function or be able to perceive and respond to stimuli, compared to control. It can refer to socket cells, sheath cells and structural cells or their processes (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000612 .
obo:GO_0040024 a rdfs:Class ;
rdfs:label "dauer larval development" ;
rdfs:comment "The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ;
rdfs:subClassOf obo:GO_0002119 .
obo:WBPhenotype_0001622 a rdfs:Class ;
rdfs:label "egg laying serotonin hypersensitive" ;
rdfs:comment "Animals lay eggs at a greater rate in response to exogenous serotonin compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000023 , obo:WBPhenotype_0001629 .
obo:WBPhenotype_0002055 a rdfs:Class ;
rdfs:label "photocurrent defective" ;
rdfs:comment "Animals do not exhibit light-induced currrents to the same extent or with the same quality as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002014 .
obo:CHEBI_38068 a rdfs:Class ;
rdfs:label "antimalarial" ;
rdfs:comment "A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human." ;
rdfs:subClassOf obo:CHEBI_64915 .
obo:CHEBI_138015 a rdfs:Class ;
rdfs:label "endocrine disruptor" ;
rdfs:comment "Any compound that can disrupt the functions of the endocrine (hormone) system" ;
rdfs:subClassOf obo:CHEBI_51061 .
obo:WBPhenotype_0000089 a rdfs:Class ;
rdfs:label "alpha amanitin resistant" ;
rdfs:comment "Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 .
obo:GO_0001939 a rdfs:Class ;
rdfs:label "female pronucleus" ;
rdfs:comment "The pronucleus originating from the ovum that is being fertilized." ;
rdfs:subClassOf obo:GO_0045120 .
obo:GO_0008021 a rdfs:Class ;
rdfs:label "synaptic vesicle" ;
rdfs:comment "A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane." ;
rdfs:subClassOf obo:GO_0070382 .
obo:GO_0046959 a rdfs:Class ;
rdfs:label "habituation" ;
rdfs:comment "A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented." ;
rdfs:subClassOf obo:GO_0046958 .
obo:GO_0042133 a rdfs:Class ;
rdfs:label "obsolete neurotransmitter metabolic process" ;
rdfs:comment "OBSOLETE. The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." .
obo:GO_0016321 a rdfs:Class ;
rdfs:label "female meiosis chromosome segregation" ;
rdfs:comment "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." ;
rdfs:subClassOf obo:GO_0045132 , obo:GO_0098813 .
obo:GO_0016740 a rdfs:Class ;
rdfs:label "transferase activity" ;
rdfs:comment "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." ;
rdfs:subClassOf obo:GO_0003824 .
obo:GO_0009629 a rdfs:Class ;
rdfs:label "response to gravity" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus." ;
rdfs:subClassOf obo:GO_0009628 .
obo:CHEBI_76988 a rdfs:Class ;
rdfs:label "xenoestrogen" ;
rdfs:comment "A synthetic or semi-synthetic compound that has oestrogenic activity." ;
rdfs:subClassOf obo:CHEBI_138015 , obo:CHEBI_50114 .
obo:CHEBI_24061 a rdfs:Class ;
rdfs:label "fluorine atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_24473 .
obo:GO_0007274 a rdfs:Class ;
rdfs:label "neuromuscular synaptic transmission" ;
rdfs:comment "The process of synaptic transmission from a neuron to a muscle, across a synapse." ;
rdfs:subClassOf obo:GO_0007268 .
obo:WBPhenotype_0001314 a rdfs:Class ;
rdfs:label "vulval muscle variant" ;
rdfs:comment "Any variation in the progression of the sex-specific muscles in the hermaphrodite, over time, that are specialized for egg-laying compared to control. In C. elegans the contractions of the vulval muscles open the lips of the vulva to help in expelling an egg from the uterus (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000282 , obo:WBPhenotype_0002551 .
obo:CHEBI_18291 a rdfs:Class ;
rdfs:label "manganese atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33352 .
obo:CHEBI_52845 a rdfs:Class ;
rdfs:label "cyclic organic group" ;
rdfs:comment "An organic group that consists of a closed ring. It may be a substituent or a skeleton." ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:CHEBI_52290 a rdfs:Class ;
rdfs:label "mitogen" ;
rdfs:comment "A chemical substance that encourages a cell to commence cell division, triggering mitosis." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_33306 a rdfs:Class ;
rdfs:label "carbon group element atom" ;
rdfs:subClassOf obo:CHEBI_33560 .
obo:GO_0007155 a rdfs:Class ;
rdfs:label "cell adhesion" ;
rdfs:comment "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0002159 a rdfs:Class ;
rdfs:label "increased pathogen accumulation" ;
rdfs:comment "Animals exhibit an increase in pathogen accumulation, persistent colonization, and luminal distension of the intestine." ;
rdfs:subClassOf obo:WBPhenotype_0001819 .
obo:WBPhenotype_0001151 a rdfs:Class ;
rdfs:label "pronucleus centrosomes defective early emb" ;
rdfs:comment "Pronucleus is abnormal in the inviable embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001034 .
obo:GO_0006402 a rdfs:Class ;
rdfs:label "mRNA catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." ;
rdfs:subClassOf obo:GO_0006401 , obo:GO_0010629 , obo:GO_0016071 .
obo:WBPhenotype_0002047 a rdfs:Class ;
rdfs:label "muscimol response variant" ;
rdfs:comment "Animals exhibit variations in their response to muscimol compared to that observed in control animals. Muscimol is a GABA-A receptor agonist." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0001493 a rdfs:Class ;
rdfs:label "VPC cell division precocious" ;
rdfs:comment "VPCs (vulval precursor cells) divide at an earlier stage of development compared to control animals; in C. elegans, VPCs divide in the mid-L3 stage to generate the 22 cells that comprise the vulva." ;
rdfs:subClassOf obo:WBPhenotype_0000345 , obo:WBPhenotype_0001495 .
obo:GO_0061564 a rdfs:Class ;
rdfs:label "axon development" ;
rdfs:comment "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)." ;
rdfs:subClassOf obo:GO_0031175 .
obo:GO_0045921 a rdfs:Class ;
rdfs:label "positive regulation of exocytosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of exocytosis." ;
rdfs:subClassOf obo:GO_0017157 , obo:GO_0065007 , obo:GO_1903532 .
obo:WBPhenotype_0001961 a rdfs:Class ;
rdfs:label "reproductive longevity extended" ;
rdfs:comment "Animals continue to produce progeny significantly past the time reproduction stops in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001739 .
obo:CHEBI_59203 a rdfs:Class ;
rdfs:label "straight-chain fatty acid anion" ;
rdfs:comment "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:WBPhenotype_0000472 a rdfs:Class ;
rdfs:label "endoderm absent" ;
rdfs:comment "Animals lack the early blast cells that give rise to the gut tissue (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:GO_0032982 a rdfs:Class ;
rdfs:label "myosin filament" ;
rdfs:comment "A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament." ;
rdfs:subClassOf obo:GO_0099512 .
obo:GO_0043066 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0043069 , obo:GO_0065007 .
obo:PATO_0001796 a rdfs:Class ;
rdfs:label "decreased coiling" ;
rdfs:comment "A coiling which is relatively low." ;
rdfs:subClassOf obo:PATO_0000404 , obo:PATO_0002303 .
obo:PATO_0050000 a rdfs:Class ;
rdfs:label "rate of occurence" ;
rdfs:comment "The number of repeated events per unit time, occurring in a repeating series. (e.g. the number of heart beats occurring over 1 minute)" ;
rdfs:subClassOf obo:PATO_0000161 .
obo:WBbt_0005736 a rdfs:Class ;
rdfs:label "excretory system" ;
rdfs:subClassOf obo:WBbt_0006850 .
obo:GO_1903464 a rdfs:Class ;
rdfs:label "negative regulation of mitotic cell cycle DNA replication" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication." ;
rdfs:subClassOf obo:GO_0045930 , obo:GO_0065007 , obo:GO_1902576 , obo:GO_1903463 .
obo:GO_1900195 a rdfs:Class ;
rdfs:label "positive regulation of oocyte maturation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of oocyte maturation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900193 , obo:GO_1903431 , obo:GO_2000243 .
obo:WBPhenotype_0000000 a rdfs:Class ;
rdfs:label "chromosome instability" ;
rdfs:comment "Variations in the frequencies of translocations, inversions, deletions, or gene amplifications and variations in chromosome fusion events and or chromosomal loss compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000585 .
obo:GO_0031113 a rdfs:Class ;
rdfs:label "regulation of microtubule polymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of microtubule polymerization." ;
rdfs:subClassOf obo:GO_0031110 , obo:GO_0032271 , obo:GO_0065007 , obo:GO_1902903 .
obo:GO_0005880 a rdfs:Class ;
rdfs:label "nuclear microtubule" ;
rdfs:comment "Any microtubule in the nucleus of a cell." ;
rdfs:subClassOf obo:GO_0005874 .
obo:GO_0015629 a rdfs:Class ;
rdfs:label "actin cytoskeleton" ;
rdfs:comment "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." ;
rdfs:subClassOf obo:GO_0005856 .
obo:WBPhenotype_0002300 a rdfs:Class ;
rdfs:label "coiling frequency increased" ;
rdfs:comment "Animals spend more time with their body posture in a coil or they increase the frequency with which they form coils compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002298 .
obo:GO_0043473 a rdfs:Class ;
rdfs:label "pigmentation" ;
rdfs:comment "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_0045839 a rdfs:Class ;
rdfs:label "negative regulation of mitotic nuclear division" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." ;
rdfs:subClassOf obo:GO_0007088 , obo:GO_0010948 , obo:GO_0045930 , obo:GO_0051784 , obo:GO_0065007 .
obo:WBPhenotype_0000766 a rdfs:Class ;
rdfs:label "centrosome pair and associated pronuclear rotation variant" ;
rdfs:comment "Any variation in the rotation of the centrosome-pronuclear complex after its migration toward the center of the embryo, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000764 .
obo:GO_0060255 a rdfs:Class ;
rdfs:label "regulation of macromolecule metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_2000381 a rdfs:Class ;
rdfs:label "negative regulation of mesoderm development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0065007 , obo:GO_2000380 .
obo:WBPhenotype_0000461 a rdfs:Class ;
rdfs:label "paraquat resistant" ;
rdfs:comment "Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000460 , obo:WBPhenotype_0001502 .
obo:CHEBI_35757 a rdfs:Class ;
rdfs:label "monocarboxylic acid anion" ;
rdfs:comment "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:CHEBI_60466 a rdfs:Class ;
rdfs:label "peptide zwitterion" ;
rdfs:comment "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:GO_0051346 a rdfs:Class ;
rdfs:label "negative regulation of hydrolase activity" ;
rdfs:comment "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds." ;
rdfs:subClassOf obo:GO_0043086 , obo:GO_0051336 , obo:GO_0065007 .
obo:GO_0007267 a rdfs:Class ;
rdfs:label "cell-cell signaling" ;
rdfs:comment "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." ;
rdfs:subClassOf obo:GO_0007154 , obo:GO_0023052 .
obo:CHEBI_35618 a rdfs:Class ;
rdfs:label "aromatic ether" ;
rdfs:comment "Any ether in which the oxygen is attached to at least one aryl substituent." ;
rdfs:subClassOf obo:CHEBI_25698 , obo:CHEBI_33659 .
obo:WBPhenotype_0000212 a rdfs:Class ;
rdfs:label "body constriction" ;
rdfs:comment "Animals contain body regions that are more narrow or drawn together than adjacent body regions." ;
rdfs:subClassOf obo:WBPhenotype_0000072 .
obo:WBPhenotype_0001325 a rdfs:Class ;
rdfs:label "backing not sustained" ;
rdfs:comment "Animals initiate but do not continue backward movement, similar to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001005 .
obo:WBPhenotype_0002407 a rdfs:Class ;
rdfs:label "egg size variant" ;
rdfs:comment "Any variation in the overall size of fertilized oocytes that are laid compared to those laid by control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000037 .
obo:WBPhenotype_0001132 a rdfs:Class ;
rdfs:label "extra cleavage furrow early emb" ;
rdfs:comment "One or more extra cleavage furrows are seen in one or more cells of a one-cell to four-cell embryo" ;
rdfs:subClassOf obo:WBPhenotype_0001129 .
obo:WBPhenotype_0002442 a rdfs:Class ;
rdfs:label "pharyngeal pump duration increased" ;
rdfs:comment "The duration of the contraction of the pharyngeal muscle during pumping is increased compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000634 .
obo:GO_0010604 a rdfs:Class ;
rdfs:label "positive regulation of macromolecule metabolic process" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0060255 , obo:GO_0065007 .
obo:WBPhenotype_0002571 a rdfs:Class ;
rdfs:label "anterior enclosure defective"@en ;
rdfs:comment "Embryos exhibit a failure to enclose the anterior embryo region with hypodermis during the comma to early elongation stage of embryonic development." ;
rdfs:subClassOf obo:WBPhenotype_0001566 .
obo:WBPhenotype_0001239 a rdfs:Class ;
rdfs:label "mating latency increased" ;
rdfs:comment "Any increase in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva." ;
rdfs:subClassOf obo:WBPhenotype_0001238 , obo:WBPhenotype_0001414 .
obo:GO_0099518 a rdfs:Class ;
rdfs:label "vesicle cytoskeletal trafficking" ;
rdfs:comment "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0030705 , obo:GO_0051650 .
obo:PATO_0002300 a rdfs:Class ;
rdfs:label "increased quality" ;
rdfs:comment "A quality that has a value that is increased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0000001 , obo:PATO_0000069 .
obo:CHEBI_24472 a rdfs:Class ;
rdfs:label "halohydrocarbon" ;
rdfs:comment "A compound derived from a hydrocarbon by replacing a hydrogen atom with a halogen atom." ;
rdfs:subClassOf obo:CHEBI_17792 .
obo:WBPhenotype_0000381 a rdfs:Class ;
rdfs:label "serotonin reuptake inhibitor resistant" ;
rdfs:comment "Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 .
obo:WBPhenotype_0001172 a rdfs:Class ;
rdfs:label "programmed cell death variant" ;
rdfs:comment "Developmentally regulated termination of a cell or cell group does not occur as in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000729 .
obo:WBPhenotype_0001444 a rdfs:Class ;
rdfs:label "aqueous adaptation defective" ;
rdfs:comment "Animals do not exhibit characteristic desensitization to a water-soluble chemo-attractive signal in a time-concentration dependent and reversible manner compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001443 .
obo:WBbt_0005776 a rdfs:Class ;
rdfs:label "excretory gland cell" ;
rdfs:comment "gland cell of the secretory-excretory system, sends processes to ring, opens into excretory duct." ;
rdfs:subClassOf obo:WBbt_0003670 , obo:WBbt_0008074 .
obo:PATO_0000957 a rdfs:Class ;
rdfs:label "opacity" ;
rdfs:comment "An optical quality which obtains by virtue of the ability of the bearer to absorb visible light." ;
rdfs:subClassOf obo:PATO_0001300 .
obo:GO_0048488 a rdfs:Class ;
rdfs:label "synaptic vesicle endocytosis" ;
rdfs:comment "A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms." ;
rdfs:subClassOf obo:GO_0140238 .
obo:CHEBI_23359 a rdfs:Class ;
rdfs:label "colchicine" ;
rdfs:comment "An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum." ;
rdfs:subClassOf obo:CHEBI_22160 , obo:CHEBI_22315 , obo:CHEBI_35618 , obo:CHEBI_38032 .
obo:GO_0070587 a rdfs:Class ;
rdfs:label "regulation of cell-cell adhesion involved in gastrulation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation." ;
rdfs:subClassOf obo:GO_0022407 , obo:GO_0065007 .
obo:GO_0140546 a rdfs:Class ;
rdfs:label "defense response to symbiont" ;
rdfs:comment "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host." ;
rdfs:subClassOf obo:GO_0098542 .
obo:WBPhenotype_0001422 a rdfs:Class ;
rdfs:label "endocytic transport defect" ;
rdfs:comment "Animals exhibit defects in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling." ;
rdfs:subClassOf obo:WBPhenotype_0001421 .
obo:GO_0000902 a rdfs:Class ;
rdfs:label "cell morphogenesis" ;
rdfs:comment "The developmental process in which the size or shape of a cell is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_35236 a rdfs:Class ;
rdfs:label "D-cysteine zwitterion" ;
rdfs:subClassOf obo:CHEBI_35237 .
obo:GO_0098693 a rdfs:Class ;
rdfs:label "regulation of synaptic vesicle cycle" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle." ;
rdfs:subClassOf obo:GO_0060627 , obo:GO_0065007 .
obo:PATO_0002000 a rdfs:Class ;
rdfs:label "lacks all parts of type" ;
rdfs:comment "A quality of physical entities inhering in a bearer by virtue of the bearer's lacking a physical part as specified by the additional entity." ;
rdfs:subClassOf obo:PATO_0001999 .
obo:GO_0007530 a rdfs:Class ;
rdfs:label "sex determination" ;
rdfs:comment "Any process that establishes and transmits the specification of sexual status of an individual organism." ;
rdfs:subClassOf obo:GO_0003006 .
obo:CHEBI_22307 a rdfs:Class ;
rdfs:label "aldoxime" ;
rdfs:comment "Oximes of aldehydes RCH=NOH." ;
rdfs:subClassOf obo:CHEBI_25750 .
obo:GO_0043207 a rdfs:Class ;
rdfs:label "response to external biotic stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." ;
rdfs:subClassOf obo:GO_0009605 , obo:GO_0009607 .
obo:GO_0060142 a rdfs:Class ;
rdfs:label "regulation of syncytium formation by plasma membrane fusion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0070507 a rdfs:Class ;
rdfs:label "regulation of microtubule cytoskeleton organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." ;
rdfs:subClassOf obo:GO_0032886 , obo:GO_0051493 , obo:GO_0065007 .
obo:WBPhenotype_0000392 a rdfs:Class ;
rdfs:label "intestinal fluorescence increased" ;
rdfs:comment "Animals exhibit an increase in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine." ;
rdfs:subClassOf obo:WBPhenotype_0000293 .
obo:WBPhenotype_0000954 a rdfs:Class ;
rdfs:label "dorsorectal ganglia development variant" ;
rdfs:comment "Any variation in the progression of the ganglion which lies above and behind the rectum in the tail, in close continuity with the anal hypodermal ridge over time from its initial formation to its mature form compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000943 .
obo:CHEBI_132717 a rdfs:Class ;
rdfs:label "bleaching agent" ;
rdfs:comment "A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties." ;
rdfs:subClassOf obo:CHEBI_33893 .
obo:WBPhenotype_0001521 a rdfs:Class ;
rdfs:label "body elongation retracted" ;
rdfs:comment "Embryos retract after the embryonic elongation process." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:WBPhenotype_0001143 a rdfs:Class ;
rdfs:label "multiple nuclei early emb" ;
rdfs:comment "Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0000746 , obo:WBPhenotype_0001142 , obo:WBPhenotype_0002413 .
obo:WBPhenotype_0002119 a rdfs:Class ;
rdfs:label "alternative splicing defective" ;
rdfs:comment "The process of generating multiple mRNA molecules from differential use of exons in a primary transcript(s) does not occur or occurs with outcomes not observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001807 .
obo:WBPhenotype_0001508 a rdfs:Class ;
rdfs:label "anchor cell fusion defective" ;
rdfs:comment "Any perturbation that disrupts the fusion between the anchor cell and the surrounding utse syncytium. Such variations result in the loss of uterine-vulval connectivity and continuity." ;
rdfs:subClassOf obo:WBPhenotype_0000165 , obo:WBPhenotype_0000283 .
obo:WBPhenotype_0000439 a rdfs:Class ;
rdfs:label "precocious heterochronic variations" ;
rdfs:comment "Variations that result in the acceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000033 .
obo:GO_1901858 a rdfs:Class ;
rdfs:label "regulation of mitochondrial DNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process." ;
rdfs:subClassOf obo:GO_0051052 , obo:GO_0065007 .
obo:WBPhenotype_0001976 a rdfs:Class ;
rdfs:comment "OBSOLETE." .
obo:CHEBI_50847 a rdfs:Class ;
rdfs:label "immunological adjuvant" ;
rdfs:comment "A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity." ;
rdfs:subClassOf obo:CHEBI_50846 , obo:CHEBI_60809 .
obo:GO_0048638 a rdfs:Class ;
rdfs:label "regulation of developmental growth" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of developmental growth." ;
rdfs:subClassOf obo:GO_0040008 , obo:GO_0050793 , obo:GO_0065007 .
obo:GO_1904803 a rdfs:Class ;
rdfs:label "regulation of translation involved in cellular response to UV" ;
rdfs:comment "Any regulation of translation that is involved in cellular response to UV." ;
rdfs:subClassOf obo:GO_0006417 .
obo:GO_1901991 a rdfs:Class ;
rdfs:label "negative regulation of mitotic cell cycle phase transition" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition." ;
rdfs:subClassOf obo:GO_0045930 , obo:GO_0065007 , obo:GO_1901988 , obo:GO_1901990 .
obo:GO_0005635 a rdfs:Class ;
rdfs:label "nuclear envelope" ;
rdfs:comment "The double lipid bilayer that encloses the nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore complexes, which regulate molecular transport." ;
rdfs:subClassOf obo:GO_0031967 .
obo:WBPhenotype_0000479 a rdfs:Class ;
rdfs:label "egg pale" ;
rdfs:comment "Eggs show deficiencies in chroma resulting in increased translucency." ;
rdfs:subClassOf obo:WBPhenotype_0000970 , obo:WBPhenotype_0001261 .
obo:WBPhenotype_0001948 a rdfs:Class ;
rdfs:label "diakinesis progression during oogenesis variant" ;
rdfs:comment "Developing oocytes show defects in their entry, progression through or exit from the diakinesis stage compared to control animals. Diakinesis is a cell cycle process comprising the steps by which a cell progresses through the final stage of prophase I in meiosis; the transition to meiotic metaphase I." ;
rdfs:subClassOf obo:WBPhenotype_0001824 .
obo:CHEBI_73333 a rdfs:Class ;
rdfs:label "scabicide" ;
rdfs:comment "An acaricide that kills mites of the genus Sarcoptes." ;
rdfs:subClassOf obo:CHEBI_22153 .
obo:WBPhenotype_0002538 a rdfs:Class ;
rdfs:label "calcium signaling in spermatheca variant"@en ;
rdfs:comment "Any variation in the series of molecular signals in which the spermatheca uses calcium ions to convert an extracellular signal into a response, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000978 , obo:WBPhenotype_0002170 .
obo:GO_0048025 a rdfs:Class ;
rdfs:label "negative regulation of mRNA splicing, via spliceosome" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism." ;
rdfs:subClassOf obo:GO_0033119 , obo:GO_0048024 , obo:GO_0050686 , obo:GO_0065007 .
obo:GO_0006275 a rdfs:Class ;
rdfs:label "regulation of DNA replication" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of DNA replication." ;
rdfs:subClassOf obo:GO_0051052 , obo:GO_0065007 .
obo:WBPhenotype_0001588 a rdfs:Class ;
rdfs:label "microtubule organization biogenesis variant" ;
rdfs:comment "Animals exhibit variations in the form, structure, composition or arrangement of a robust macromolecular array, composed primarily of tubulin, which forms long extended cytoskeletal elements compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001345 .
obo:WBPhenotype_0002650 a rdfs:Class ;
rdfs:label "egg laying response to pathogen lipopolysaccharide variant"@en ;
rdfs:comment "Characteristic response to extracted lipopolysaccharide from pathogens with respect to egg-laying behavior varies compared to control conditions." ;
rdfs:subClassOf obo:WBPhenotype_0002649 .
obo:CHEBI_61115 a rdfs:Class ;
rdfs:label "EC 3.5.1.98 (histone deacetylase) inhibitor" ;
rdfs:comment "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98)." ;
rdfs:subClassOf obo:CHEBI_76807 .
obo:WBPhenotype_0000312 a rdfs:Class ;
rdfs:label "dauer pheromone production defective" ;
rdfs:comment "Animals are incapable of synthesizing pheromones that induce dauer formation in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000191 , obo:WBPhenotype_0001547 .
obo:GO_0080154 a rdfs:Class ;
rdfs:label "regulation of fertilization" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000241 .
obo:CHEBI_24859 a rdfs:Class ;
rdfs:label "iodine atom" ;
rdfs:comment "Chemical element with atomic number 53." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_24473 .
obo:CHEBI_15986 a rdfs:Class ;
rdfs:label "polynucleotide" ;
rdfs:comment "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." ;
rdfs:subClassOf obo:CHEBI_33695 , obo:CHEBI_61120 .
obo:CHEBI_83820 a rdfs:Class ;
rdfs:label "non-proteinogenic amino acid" ;
rdfs:comment "Any amino-acid that is not naturally encoded in the genetic code of any organism." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:WBPhenotype_0002635 a rdfs:Class ;
rdfs:label "epidermal shedding"@en ;
rdfs:comment "Animals shed fragments of epidermis into the surrounding environment, unlike controls. In embryos, these fragments can be seen in the extra-embryonic space." ;
rdfs:subClassOf obo:WBPhenotype_0000619 .
obo:WBPhenotype_0001183 a rdfs:Class ;
rdfs:label "fat content reduced" ;
rdfs:comment "Animals exhibit less fat or lipid than observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001182 .
obo:GO_1905852 a rdfs:Class ;
rdfs:label "positive regulation of backward locomotion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of backward locomotion." ;
rdfs:subClassOf obo:GO_0040017 , obo:GO_0043058 , obo:GO_0065007 .
obo:WBPhenotype_0000631 a rdfs:Class ;
rdfs:label "drug response variant" ;
rdfs:comment "Any variation in the characteristic response(s) to drug(s) as defined by control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:GO_0006984 a rdfs:Class ;
rdfs:label "ER-nucleus signaling pathway" ;
rdfs:comment "The series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation." ;
rdfs:subClassOf obo:GO_0035556 .
obo:WBPhenotype_0002239 a rdfs:Class ;
rdfs:label "reduced levels of reactive oxygen species" ;
rdfs:comment "Animals exhibit reduced endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002182 .
obo:GO_1900242 a rdfs:Class ;
rdfs:label "regulation of synaptic vesicle endocytosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis." ;
rdfs:subClassOf obo:GO_0030100 , obo:GO_0065007 , obo:GO_1903421 .
obo:WBPhenotype_0000792 a rdfs:Class ;
rdfs:label "anterior body morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of the anatomy contained in the anterior region, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000072 , obo:WBPhenotype_0000581 .
obo:WBPhenotype_0000826 a rdfs:Class ;
rdfs:label "H lineages variant" ;
rdfs:comment "The descendants of H1 or H2 cells exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000825 .
obo:WBPhenotype_0001277 a rdfs:Class ;
rdfs:label "transformer" ;
rdfs:comment "XX animals are transformed into males or pseudomales ." ;
rdfs:subClassOf obo:WBPhenotype_0001572 .
obo:GO_0018991 a rdfs:Class ;
rdfs:label "egg-laying behavior" ;
rdfs:comment "A reproductive behavior that results in the deposition of eggs (either fertilized or not) upon a surface or into a medium such as water." ;
rdfs:subClassOf obo:GO_0019098 .
obo:GO_0099503 a rdfs:Class ;
rdfs:label "secretory vesicle" ;
rdfs:comment "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." ;
rdfs:subClassOf obo:GO_0031410 .
obo:WBPhenotype_0002167 a rdfs:Class ;
rdfs:label "transgenerational accumulation of histone methylation" ;
rdfs:comment "The amount of histone methylation, for example as measured by the amount of H3K4me2, increases over successive generations" ;
rdfs:subClassOf obo:WBPhenotype_0002078 .
obo:WBPhenotype_0002258 a rdfs:Class ;
rdfs:label "nickel toxicity resistant" ;
rdfs:comment "Animals fail to exhibit toxicity to the concentration of nickel that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to nickel include delayed development or lethality." ;
rdfs:subClassOf obo:WBPhenotype_0000591 , obo:WBPhenotype_0001502 .
obo:WBPhenotype_0002527 a rdfs:Class ;
rdfs:label "dauer larva physiology variant"@en ;
rdfs:comment "Animals in the dauer larval stage exhibit variations in their physiology (any biological process including but not limited to development, behavior, or metabolism) compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001293 .
obo:WBPhenotype_0000343 a rdfs:Class ;
rdfs:label "obsolete cloaca morphology abnormal" ;
rdfs:comment "OBSOLETE." .
obo:CHEBI_83565 a rdfs:Class ;
rdfs:label "(trifluoromethyl)benzenes" ;
rdfs:comment "An organofluorine compound that is (trifluoromethyl)benzene and derivatives arising from substitution of one or more of the phenyl hydrogens." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_37143 .
obo:WBPhenotype_0001864 a rdfs:Class ;
rdfs:label "protein transport variant" ;
rdfs:comment "Any variation in the processes that modulate the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001644 , obo:WBPhenotype_0001833 .
obo:WBPhenotype_0001059 a rdfs:Class ;
rdfs:label "magnesium chemotaxis defective" ;
rdfs:comment "Animals fail to exhibit the same taxis behavior as control animals in response to magnesium. In C. elegans, this is characterized by the failure to move towards magnesium." ;
rdfs:subClassOf obo:WBPhenotype_0001440 .
obo:GO_0140014 a rdfs:Class ;
rdfs:label "mitotic nuclear division" ;
rdfs:comment "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." ;
rdfs:subClassOf obo:GO_0000280 , obo:GO_1903047 .
obo:CHEBI_58953 a rdfs:Class ;
rdfs:label "saturated fatty acid anion" ;
rdfs:comment "Any fatty acid anion in which there is no C‒C unsaturation." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:WBPhenotype_0000160 a rdfs:Class ;
rdfs:label "cleavage furrow not discrete early emb" ;
rdfs:comment "Embryos do not form a defined shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ;
rdfs:subClassOf obo:WBPhenotype_0001129 .
obo:WBPhenotype_0002394 a rdfs:Class ;
rdfs:label "phagosome sealing defective" ;
rdfs:comment "The closure of a phagosome does not occur and it remains connected with the plasma membrane, leaving the lumen open to the outside. Complete closure usually occurs once an apoptotic cell has been surrounded by an engulfing cell." ;
rdfs:subClassOf obo:WBPhenotype_0000885 .
obo:GO_0060560 a rdfs:Class ;
rdfs:label "developmental growth involved in morphogenesis" ;
rdfs:comment "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." ;
rdfs:subClassOf obo:GO_0048589 .
obo:WBPhenotype_0000181 a rdfs:Class ;
rdfs:label "axon trajectory variant" ;
rdfs:comment "Animals display variations in the directed path taken by the axon compared to the path the nerve fiber follows in the nervous system in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000180 .
obo:CHEBI_37699 a rdfs:Class ;
rdfs:label "protein kinase inhibitor" ;
rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases." ;
rdfs:subClassOf obo:CHEBI_76668 .
obo:CHEBI_36683 a rdfs:Class ;
rdfs:label "organochlorine compound" ;
rdfs:comment "An organochlorine compound is a compound containing at least one carbon-chlorine bond." ;
rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_23117 .
obo:GO_0032228 a rdfs:Class ;
rdfs:label "regulation of synaptic transmission, GABAergic" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 .
obo:GO_1905552 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to endoplasmic reticulum" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903829 , obo:GO_1905550 .
obo:GO_0032501 a rdfs:Class ;
rdfs:label "multicellular organismal process" ;
rdfs:comment "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_0045132 a rdfs:Class ;
rdfs:label "meiotic chromosome segregation" ;
rdfs:comment "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0098813 , obo:GO_1903046 .
obo:WBbt_0008423 a rdfs:Class ;
rdfs:label "male genital" ;
rdfs:comment "antomical structure of the male involved in sexual reproduction." ;
rdfs:subClassOf obo:WBbt_0005757 , obo:WBbt_0008422 .
obo:WBPhenotype_0001054 a rdfs:Class ;
rdfs:label "cGMP chemotaxis defective" ;
rdfs:comment "Animals fail to exhibit the same taxis behavior as control animals in response to cGMP. In C. elegans, this is characterized by the failure to move towards cGMP." ;
rdfs:subClassOf obo:WBPhenotype_0001441 , obo:WBPhenotype_0001464 .
obo:GO_0050926 a rdfs:Class ;
rdfs:label "regulation of positive chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." ;
rdfs:subClassOf obo:GO_0050920 , obo:GO_0065007 .
obo:GO_0042330 a rdfs:Class ;
rdfs:label "taxis" ;
rdfs:comment "The directed movement of a motile cell or organism in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0040011 .
obo:CHEBI_149484 a rdfs:Class ;
rdfs:label "chloroquine(2+)" ;
rdfs:comment "A quinolinium ion obtained by protonation of the quinoline nitrogen and tertiary amino group of the antimalarial drug chloroquine. It is the major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_137982 , obo:CHEBI_52837 .
obo:GO_0005881 a rdfs:Class ;
rdfs:label "cytoplasmic microtubule" ;
rdfs:comment "Any microtubule in the cytoplasm of a cell." ;
rdfs:subClassOf obo:GO_0005874 .
obo:WBPhenotype_0000175 a rdfs:Class ;
rdfs:label "hypercontracted" ;
rdfs:comment "Excessive and often uncoordinated body wall muscle contraction leading to shortening of the body." ;
rdfs:subClassOf obo:WBPhenotype_0000001 .
obo:WBPhenotype_0002488 a rdfs:Class ;
rdfs:label "intestinal integrity increased"@en ;
rdfs:comment "Animals exhibit an increase in the integrity of the intestine, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002487 .
obo:CHEBI_15693 a rdfs:Class ;
rdfs:label "aldose" ;
rdfs:comment "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n ≥ 2) and their intramolecular hemiacetals." ;
rdfs:subClassOf obo:CHEBI_35381 .
obo:WBPhenotype_0002116 a rdfs:Class ;
rdfs:label "subviable" ;
rdfs:comment "Animals are barely alive, but not entirely dead." ;
rdfs:subClassOf obo:WBPhenotype_0000531 , obo:WBPhenotype_0000576 .
obo:CHEBI_36902 a rdfs:Class ;
rdfs:label "chalcogen hydride" ;
rdfs:subClassOf obo:CHEBI_33242 , obo:CHEBI_33304 .
obo:WBPhenotype_0000301 a rdfs:Class ;
rdfs:label "distal tip cell reflex failure" ;
rdfs:comment "A migrating distal tip cell (DTC) fails to follow the stereotypical path. In C. elegans this path is U-shaped and results in the formation of reflexed gonadal arm." ;
rdfs:subClassOf obo:WBPhenotype_0000195 .
obo:WBPhenotype_0001014 a rdfs:Class ;
rdfs:label "pathogen resistance increased" ;
rdfs:comment "Animals are less prone to infection compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001012 .
obo:GO_0010454 a rdfs:Class ;
rdfs:label "negative regulation of cell fate commitment" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ;
rdfs:subClassOf obo:GO_0010453 , obo:GO_0045596 , obo:GO_0065007 .
obo:GO_0051785 a rdfs:Class ;
rdfs:label "positive regulation of nuclear division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0051783 , obo:GO_0065007 .
obo:CHEBI_86315 a rdfs:Class ;
rdfs:label "methyl sulfide" ;
rdfs:comment "Any aliphatic sulfide in which at least one of the organyl groups attached to the sulfur is a methyl group." ;
rdfs:subClassOf obo:CHEBI_16385 .
obo:GO_0043264 a rdfs:Class ;
rdfs:label "extracellular membraneless organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." ;
rdfs:subClassOf obo:GO_0043228 , obo:GO_0043230 .
obo:WBPhenotype_0004015 a rdfs:Class ;
rdfs:label "pre male contact variant" ;
rdfs:comment "Any variation in the specific actions or reactions of a hermaphrodite prior to male contact during mating compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0004001 .
obo:WBPhenotype_0001671 a rdfs:Class ;
rdfs:label "vesicle organization variant" ;
rdfs:comment "Animals display variations in the distribution of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000519 , obo:WBPhenotype_0002089 .
obo:GO_1902667 a rdfs:Class ;
rdfs:label "regulation of axon guidance" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of axon guidance." ;
rdfs:subClassOf obo:GO_0010975 , obo:GO_0050920 , obo:GO_0065007 .
obo:WBPhenotype_0001686 a rdfs:Class ;
rdfs:label "postsynaptic region physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process in the region, opposite to the presynaptic region, which is required for receiving signals from the other side of the synapse compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000584 .
obo:WBPhenotype_0002076 a rdfs:Class ;
rdfs:label "cortical granule exocytosis variant" ;
rdfs:comment "The process of secretion by a cell that results in the release of intracellular molecules contained within a specialized secretory vesicle that fuses with the plasma membrane during egg activation." ;
rdfs:subClassOf obo:WBPhenotype_0002075 .
obo:WBPhenotype_0000943 a rdfs:Class ;
rdfs:label "ganglion development variant" ;
rdfs:comment "Any variation in the progression of a cluster of neuron cell bodies (somata) over time from its initial formation to its mature form compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000623 .
obo:WBPhenotype_0001060 a rdfs:Class ;
rdfs:label "AWC odorant chemotaxis defective" ;
rdfs:comment "In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWC compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001438 .
obo:CHEBI_32876 a rdfs:Class ;
rdfs:label "tertiary amine" ;
rdfs:comment "A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups." ;
rdfs:subClassOf obo:CHEBI_32952 , obo:CHEBI_50996 .
obo:CHEBI_24471 a rdfs:Class ;
rdfs:label "halogen molecular entity" ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:WBPhenotype_0001333 a rdfs:Class ;
rdfs:label "neuron cell body absent misplaced" ;
rdfs:comment "The body of a neuron is not where it should be when compared to control animals; it is absent or misplaced." ;
rdfs:subClassOf obo:WBPhenotype_0000816 .
obo:CHEBI_39447 a rdfs:Class ;
rdfs:label "pyrimidines" ;
rdfs:comment "Any compound having a pyrimidine as part of its structure." ;
rdfs:subClassOf obo:CHEBI_38313 .
obo:WBPhenotype_0001545 a rdfs:Class ;
rdfs:label "dauer body morphology variant" ;
rdfs:comment "Any variation in the overall structure or appearance of an animal progressing through an alternative larval stage in response to environmental stresses compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000934 , obo:WBPhenotype_0002555 .
obo:PATO_0000570 a rdfs:Class ;
rdfs:label "increased height" ;
rdfs:comment "A height which is relatively high." ;
rdfs:subClassOf obo:PATO_0000119 , obo:PATO_0000586 .
obo:GO_1903532 a rdfs:Class ;
rdfs:label "positive regulation of secretion by cell" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of secretion by cell." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0051047 , obo:GO_0065007 , obo:GO_1903530 .
obo:WBls_0000669 a rdfs:Class ;
rdfs:label "unfertilized egg Ce" ;
rdfs:comment "A developmental life stage of the nematode Caenorhabditis elegans that occurs in an egg (oocyte), before fertilization by sperm." ;
rdfs:subClassOf obo:WBls_0000825 .
obo:GO_0050789 a rdfs:Class ;
rdfs:label "regulation of biological process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ;
rdfs:subClassOf obo:GO_0065007 .
obo:GO_0032878 a rdfs:Class ;
rdfs:label "regulation of establishment or maintenance of cell polarity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0002297 a rdfs:Class ;
rdfs:label "coiling variant" ;
rdfs:comment "Animals exhibit variations in the occurrence of a coil-like body posture compared to control animals. This includes the amount of time spent in a coil, the frequency with which coils form and the inappropriate formation of a coil, for example when attempting to locomote." ;
rdfs:subClassOf obo:WBPhenotype_0000001 .
obo:PATO_0000016 a rdfs:Class ;
rdfs:label "color brightness" ;
rdfs:comment "A scalar optical property that is the intensity, value or amount of perceived light." ;
rdfs:subClassOf obo:PATO_0001300 .
obo:PATO_0000760 a rdfs:Class ;
rdfs:label "increased behavioural activity" ;
rdfs:comment "A behavioral quality of a process inhering in a bearer by virtue of the bearer's exhibiting increased activity." ;
rdfs:subClassOf obo:PATO_0001707 , obo:PATO_0002305 .
obo:GO_2000105 a rdfs:Class ;
rdfs:label "positive regulation of DNA-templated DNA replication" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication." ;
rdfs:subClassOf obo:GO_0045740 , obo:GO_0065007 , obo:GO_0090329 .
obo:GO_0042592 a rdfs:Class ;
rdfs:label "homeostatic process" ;
rdfs:comment "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." ;
rdfs:subClassOf obo:GO_0008150 .
obo:WBPhenotype_0002349 a rdfs:Class ;
rdfs:label "phosphatidylinositol 3-phosphate levels reduced" ;
rdfs:comment "The levels of phosphatidylinositol 3-phosphate (a.k.a. PtdIns3P or PI3P) are reduced compared to those of control animals" ;
rdfs:subClassOf obo:WBPhenotype_0000138 , obo:WBPhenotype_0001183 .
obo:CHEBI_132992 a rdfs:Class ;
rdfs:label "radiosensitizing agent" ;
rdfs:comment "A drug that makes increases the sensitivity of tumour cells to radiation therapy." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:CHEBI_33958 a rdfs:Class ;
rdfs:label "halide salt" ;
rdfs:subClassOf obo:CHEBI_24866 , obo:CHEBI_37578 .
obo:WBPhenotype_0001824 a rdfs:Class ;
rdfs:label "meiotic progression prophase variant" ;
rdfs:comment "Animals exhibit variations in any process necessary for the progression through prophase during meiosis compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000313 , obo:WBPhenotype_0000775 .
obo:CHEBI_2814 a rdfs:Class ;
rdfs:label "arecoline" ;
rdfs:comment "A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine." ;
rdfs:subClassOf obo:CHEBI_25248 , obo:CHEBI_26416 , obo:CHEBI_26921 , obo:CHEBI_51702 .
obo:CHEBI_26144 a rdfs:Class ;
rdfs:label "piperazines" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:WBPhenotype_0002462 a rdfs:Class ;
rdfs:label "pathogen adherence increased" ;
rdfs:comment "Pathogens exhibit increased adherence to the surface of host animals." ;
rdfs:subClassOf obo:WBPhenotype_0001415 .
obo:GO_0040027 a rdfs:Class ;
rdfs:label "negative regulation of vulval development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ;
rdfs:subClassOf obo:GO_0040028 , obo:GO_0061064 , obo:GO_0065007 .
obo:GO_0007269 a rdfs:Class ;
rdfs:label "neurotransmitter secretion" ;
rdfs:comment "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." ;
rdfs:subClassOf obo:GO_0006836 , obo:GO_0051649 , obo:GO_0099643 .
obo:GO_1900117 a rdfs:Class ;
rdfs:label "regulation of execution phase of apoptosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of execution phase of apoptosis." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0001188 a rdfs:Class ;
rdfs:label "radial filament structure variant pharynx" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of radial arrangement of actin within the pharyngeal muscle compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001046 .
obo:WBPhenotype_0000855 a rdfs:Class ;
rdfs:label "pseudocoelom development variant" ;
rdfs:comment "Variations in the progression of the fluid-filled space which separates the body wall from internal organs over time from its initial formation to its mature form compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000200 , obo:WBPhenotype_0000528 .
obo:CHEBI_64228 a rdfs:Class ;
rdfs:label "tunicamycin A0" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 11-methyldodec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:CHEBI_50177 a rdfs:Class ;
rdfs:label "dermatologic drug" ;
rdfs:comment "A drug used to treat or prevent skin disorders or for the routine care of skin." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:WBPhenotype_0002383 a rdfs:Class ;
rdfs:label "light touch habituation variant" ;
rdfs:comment "Any variation in the decreased behavioral response to repeated light head or tail touch compared to control. A gentle touch to the animal's head causes backward movement, whereas a gentle touch to the animal's tail causes forward movement. When wild-type animals are touched repeatedly on the head or tail, after some repetition they stop responding to the touch stimulus." ;
rdfs:subClassOf obo:WBPhenotype_0000626 .
obo:WBPhenotype_0000112 a rdfs:Class ;
rdfs:label "protein expression variant" ;
rdfs:comment "Variations in the biogenesis and stability of protein molecules compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:GO_1901698 a rdfs:Class ;
rdfs:label "response to nitrogen compound" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." ;
rdfs:subClassOf obo:GO_0042221 .
obo:CHEBI_26766 a rdfs:Class ;
rdfs:label "steroid lactone" ;
rdfs:subClassOf obo:CHEBI_25000 , obo:CHEBI_35341 .
obo:WBPhenotype_0000647 a rdfs:Class ;
rdfs:label "copulation variant" ;
rdfs:comment "Animals exhibit variations in any processes that lead to the successful transfer of sperm from one organism to another." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:WBPhenotype_0002065 a rdfs:Class ;
rdfs:label "basement membrane remodeling variant" ;
rdfs:comment "Animals display variations in the manner in which the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) is remodeled, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000200 , obo:WBPhenotype_0002588 .
obo:GO_0045700 a rdfs:Class ;
rdfs:label "regulation of spermatid nuclear differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 , obo:GO_1903353 .
obo:GO_0033363 a rdfs:Class ;
rdfs:label "secretory granule organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." ;
rdfs:subClassOf obo:GO_0016050 .
obo:CHEBI_48706 a rdfs:Class ;
rdfs:label "antagonist" ;
rdfs:comment "Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:WBPhenotype_0000699 a rdfs:Class ;
rdfs:label "vulva development variant" ;
rdfs:comment "Variations in the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure compared to control. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ;
rdfs:subClassOf obo:WBPhenotype_0000624 .
obo:GO_0002684 a rdfs:Class ;
rdfs:label "positive regulation of immune system process" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of an immune system process." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0048518 , obo:GO_0065007 .
obo:GO_0030030 a rdfs:Class ;
rdfs:label "cell projection organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." ;
rdfs:subClassOf obo:GO_0016043 .
obo:WBPhenotype_0002008 a rdfs:Class ;
rdfs:label "glycation variant" ;
rdfs:comment "Animals exhibit variations in the non-enzymatic glycosylation process of attaching a protein or lipid to a sugar molecule, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0001268 a rdfs:Class ;
rdfs:label "induced cell death variant" ;
rdfs:comment "Animals exhibit variations in the extent of activation of programmed cell death, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000729 .
obo:CHEBI_33240 a rdfs:Class ;
rdfs:label "coordination entity" ;
rdfs:comment "An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands)." ;
rdfs:subClassOf obo:CHEBI_37577 .
obo:WBPhenotype_0001392 a rdfs:Class ;
rdfs:label "cell cycle arrest" ;
rdfs:comment "Cells of the animals cease during one of its replicative phases (G1, S, G2, M)." ;
rdfs:subClassOf obo:WBPhenotype_0001995 .
obo:WBPhenotype_0000921 a rdfs:Class ;
rdfs:label "striated muscle development variant" ;
rdfs:comment "Variations in the progression of muscle cells that contain fibers that are divided by transverse bands into striations, over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000622 , obo:WBPhenotype_0000990 .
obo:WBPhenotype_0000869 a rdfs:Class ;
rdfs:label "obsolete mitochondria morphology variant muscle" ;
rdfs:comment "OBSOLETE." .
obo:CHEBI_36586 a rdfs:Class ;
rdfs:label "carbonyl compound" ;
rdfs:comment "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." ;
rdfs:subClassOf obo:CHEBI_36587 , obo:CHEBI_36963 .
obo:CHEBI_33280 a rdfs:Class ;
rdfs:label "molecular messenger" ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:GO_2000747 a rdfs:Class ;
rdfs:label "negative regulation of defecation rhythm" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000293 , obo:GO_2000746 .
obo:WBPhenotype_0000259 a rdfs:Class ;
rdfs:label "sheath cell secretion variant" ;
rdfs:comment "Variations in the regulated release of substances by nonneuronal cells that enclose or ensheath the tips of the sensory dendrites compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000258 .
obo:WBPhenotype_0000619 a rdfs:Class ;
rdfs:label "epithelial system development variant" ;
rdfs:comment "Any variation in the progression of the epithelial system over time, from its formation to its mature state compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000530 .
obo:CL_0000586 a rdfs:Class ;
rdfs:label "germ cell" ;
rdfs:comment "The reproductive cell in multicellular organisms." ;
rdfs:subClassOf obo:CL_0000039 .
obo:WBPhenotype_0001370 a rdfs:Class ;
rdfs:label "protein protein interaction variant" ;
rdfs:comment "Variations in the selective and non-covalent physical association between two or more proteins, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001369 .
obo:WBPhenotype_0000201 a rdfs:Class ;
rdfs:label "cuticle development variant" ;
rdfs:comment "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time compared to control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000200 .
obo:WBPhenotype_0001433 a rdfs:Class ;
rdfs:label "precocious cell fusion" ;
rdfs:comment "Two or more individual cells form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes at an earlier stage of development compared to comparable cells in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000165 , obo:WBPhenotype_0000439 .
obo:CHEBI_33909 a rdfs:Class ;
rdfs:label "metallotetrapyrrole" ;
rdfs:subClassOf obo:CHEBI_36309 .
obo:GO_1903379 a rdfs:Class ;
rdfs:label "regulation of mitotic chromosome condensation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0060623 , obo:GO_0065007 .
obo:WBPhenotype_0000727 a rdfs:Class ;
rdfs:label "enzyme activity variant" ;
rdfs:comment "Any variation in the function of naturally occurring macromolecular substances known as enzymes compared to control. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0000658 a rdfs:Class ;
rdfs:label "neuromuscular synaptic transmission variant" ;
rdfs:comment "Any variation in the process of communication across a synapse between a neuron and a target muscle cell compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000584 .
obo:GO_0140513 a rdfs:Class ;
rdfs:label "nuclear protein-containing complex" ;
rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus." ;
rdfs:subClassOf obo:GO_0032991 .
obo:WBPhenotype_0002507 a rdfs:Class ;
rdfs:label "pathogen infection clearance rate decreased"@en ;
rdfs:comment "Infected animals exhibit a decreased rate of clearance of pathogen infection compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002505 .
obo:WBPhenotype_0001813 a rdfs:Class ;
rdfs:label "synapsis defective" ;
rdfs:comment "Animals exhibit defects in the stabilization of homologue pairing, which occurs through the initiation and formation of the synaptonemal complex, during meiosis." ;
rdfs:subClassOf obo:WBPhenotype_0002012 .
obo:CHEBI_33575 a rdfs:Class ;
rdfs:label "carboxylic acid" ;
rdfs:comment "A carbon oxoacid acid carrying at least one ‒C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." ;
rdfs:subClassOf obo:CHEBI_35605 , obo:CHEBI_36586 , obo:CHEBI_64709 .
obo:WBPhenotype_0000777 a rdfs:Class ;
rdfs:label "polar body extrusion defective early emb" ;
rdfs:comment "Unextruded or resorbed polar body(ies) leading to an extra PNs in P0 and/or extra karyomeres in AB/P1." ;
rdfs:subClassOf obo:WBPhenotype_0000775 , obo:WBPhenotype_0001147 .
obo:CHEBI_60832 a rdfs:Class ;
rdfs:label "tubulin modulator" ;
rdfs:comment "Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:CL_0000219 a rdfs:Class ;
rdfs:label "motile cell" ;
rdfs:comment "A cell that moves by its own activities." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0060280 a rdfs:Class ;
rdfs:label "negative regulation of ovulation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." ;
rdfs:subClassOf obo:GO_0051241 , obo:GO_0060278 , obo:GO_0065007 , obo:GO_2000242 .
obo:WBPhenotype_0001693 a rdfs:Class ;
rdfs:label "male posterior alae" ;
rdfs:comment "Males have alae that extend into the tail region. Alae are small linear ridges running along the lateral lines of the cuticle. In C. elegans alae do not extend into the tail region (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000202 , obo:WBPhenotype_0001240 .
obo:GO_0072667 a rdfs:Class ;
rdfs:label "maintenance of protein location in vacuole" ;
rdfs:comment "Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0072595 .
obo:WBPhenotype_0002087 a rdfs:Class ;
rdfs:label "hydrogen sulfide hypersensitive" ;
rdfs:comment "Animals respond to hydrogen sulfide at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001918 .
obo:GO_0030307 a rdfs:Class ;
rdfs:label "positive regulation of cell growth" ;
rdfs:comment "Any process that activates or increases the frequency, rate, extent or direction of cell growth." ;
rdfs:subClassOf obo:GO_0001558 , obo:GO_0045927 , obo:GO_0048522 , obo:GO_0065007 .
obo:WBbt_0008429 a rdfs:Class ;
rdfs:label "polar body" ;
rdfs:comment "One of two small cells produced, each during one of the two meiotic cell divisions, which are then discarded in the creation of the haploid germ cell." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBPhenotype_0000963 a rdfs:Class ;
rdfs:label "male pigmentation variant" ;
rdfs:comment "Males exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000527 , obo:WBPhenotype_0001024 .
obo:PATO_0001558 a rdfs:Class ;
rdfs:label "lacking processual parts" ;
rdfs:comment "A quality of a process inhering in a bearer by virtue of the bearer's lacking a processual part as specified by the additional entity." ;
rdfs:subClassOf obo:PATO_0001564 .
obo:WBPhenotype_0000249 a rdfs:Class ;
rdfs:label "osmotic avoidance defective" ;
rdfs:comment "Failure to execute the characteristic avoidance response to solutions of high osmotic strength as defined by control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000663 .
obo:GO_0098797 a rdfs:Class ;
rdfs:label "plasma membrane protein complex" ;
rdfs:comment "Any protein complex that is part of the plasma membrane." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0098796 .
obo:WBPhenotype_0001772 a rdfs:Class ;
rdfs:label "endogenous transposase levels increased" ;
rdfs:comment "Animals exhibit an increase in the levels of transposase mRNA, from endogenous transposons, over that measured in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000745 .
obo:WBPhenotype_0002147 a rdfs:Class ;
rdfs:label "small RNA somatic expression variant" ;
rdfs:comment "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in somatic cells. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs)." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:WBPhenotype_0002205 a rdfs:Class ;
rdfs:label "hypersensitive to galactose" ;
rdfs:comment "Animals exhibit negative effects on growth, development, or metabolism when exposed to a galactose-rich diet, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000027 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001162 a rdfs:Class ;
rdfs:label "pronuclear number defective early emb" ;
rdfs:comment "There are more than two pronuclei in the inviable embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001142 , obo:WBPhenotype_0001151 .
obo:GO_0061067 a rdfs:Class ;
rdfs:label "negative regulation of dauer larval development" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ;
rdfs:subClassOf obo:GO_0061064 , obo:GO_0061065 , obo:GO_0065007 .
obo:GO_0000279 a rdfs:Class ;
rdfs:label "M phase" ;
rdfs:comment "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase." ;
rdfs:subClassOf obo:GO_0022403 .
obo:WBPhenotype_0000238 a rdfs:Class ;
rdfs:label "foraging reduced" ;
rdfs:comment "Animals decrease intensity or rate of roaming and or dwelling activity compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000662 .
obo:GO_0044088 a rdfs:Class ;
rdfs:label "regulation of vacuole organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:PATO_0001677 a rdfs:Class ;
rdfs:label "inefficient" ;
rdfs:comment "An efficiency quality inhering in a bearer by virtue of the bearer's lacking efficiency." ;
rdfs:subClassOf obo:PATO_0001029 .
obo:WBPhenotype_0000197 a rdfs:Class ;
rdfs:label "cell induction variant" ;
rdfs:comment "Variations in a cell's ability to influence the fate of another cell (often of different developmental potential or ancestry via short range signaling)." ;
rdfs:subClassOf obo:WBPhenotype_0000216 .
obo:WBPhenotype_0000809 a rdfs:Class ;
rdfs:label "male specific lineage variant" ;
rdfs:comment "The descendants of a male specific precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000825 .
obo:CHEBI_17062 a rdfs:Class ;
rdfs:label "primary aliphatic amine" ;
rdfs:subClassOf obo:CHEBI_32877 .
obo:GO_1901995 a rdfs:Class ;
rdfs:label "positive regulation of meiotic cell cycle phase transition" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition." ;
rdfs:subClassOf obo:GO_0051446 , obo:GO_0065007 , obo:GO_1901989 , obo:GO_1901993 .
obo:GO_0006584 a rdfs:Class ;
rdfs:label "catecholamine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ;
rdfs:subClassOf obo:GO_0006576 , obo:GO_0009712 .
obo:WBPhenotype_0000530 a rdfs:Class ;
rdfs:label "organ system development variant" ;
rdfs:comment "Any variation in the progression of an organismal system from its formation to the mature structure when compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000518 .
obo:NCBITaxon_33208 a rdfs:Class .
obo:WBPhenotype_0001853 a rdfs:Class ;
rdfs:label "AAD response variant" ;
rdfs:comment "Animals exhibit variations in their response to the amino-acetonitrile derivatives (AADs) class of synthetic anthelmintics, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001852 .
obo:CL_0000151 a rdfs:Class ;
rdfs:label "secretory cell" ;
rdfs:comment "A cell that specializes in controlled release of one or more substances." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0045893 a rdfs:Class ;
rdfs:label "positive regulation of DNA-templated transcription" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription." ;
rdfs:subClassOf obo:GO_0006355 , obo:GO_0065007 , obo:GO_1902680 .
obo:GO_0006279 a rdfs:Class ;
rdfs:label "premeiotic DNA replication" ;
rdfs:comment "The replication of DNA that precedes meiotic cell division." ;
rdfs:subClassOf obo:GO_0033260 , obo:GO_1903046 .
obo:WBbt_0008593 a rdfs:Class ;
rdfs:label "Q lineage cell" ;
rdfs:comment "A cell that is QL or QR blast cell or is a lineal descendant of QL or QR." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_2000785 a rdfs:Class ;
rdfs:label "regulation of autophagosome assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of autophagosome assembly." ;
rdfs:subClassOf obo:GO_0044088 , obo:GO_0065007 , obo:GO_1902115 .
obo:GO_2000003 a rdfs:Class ;
rdfs:label "positive regulation of DNA damage checkpoint" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901978 , obo:GO_2000001 .
obo:WBPhenotype_0001309 a rdfs:Class ;
rdfs:label "amplitude of sinusoidal movement decreased" ;
rdfs:comment "Animals exhibit a decrease in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0004022 .
obo:WBPhenotype_0000154 a rdfs:Class ;
rdfs:label "reduced brood size" ;
rdfs:comment "The characteristic number of offspring produced is lower compared to that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000673 .
obo:CHEBI_65296 a rdfs:Class ;
rdfs:label "primary ammonium ion" ;
rdfs:comment "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:WBPhenotype_0000186 a rdfs:Class ;
rdfs:label "oogenesis variant" ;
rdfs:comment "Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000812 , obo:WBPhenotype_0000894 .
obo:WBPhenotype_0001534 a rdfs:Class ;
rdfs:label "neuronal ECM variant" ;
rdfs:comment "Any variation in makeup, density or area of the ECM lending structure to neurons compared to control animals. In C. elegans, the neuronal ECM is sometimes referred to as a mantle." ;
rdfs:subClassOf obo:WBPhenotype_0001523 .
obo:WBPhenotype_0000011 a rdfs:Class ;
rdfs:label "drug resistant" ;
rdfs:comment "Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0000554 a rdfs:Class ;
rdfs:label "hypoosmotic shock hypersensitive" ;
rdfs:comment "Any variation in the ability to adjust to a decline in ambient solute concentrations, thereby causing the body to swell and explode." ;
rdfs:subClassOf obo:WBPhenotype_0000041 .
obo:CHEBI_4887 a rdfs:Class ;
rdfs:label "ethosuximide" ;
rdfs:comment "A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35356 , obo:CHEBI_38275 .
obo:WBPhenotype_0002672 a rdfs:Class ;
rdfs:label "shortened healthspan"@en ;
rdfs:comment "Animals exhibit a shortening of healthspan, the period within which animals are or appear to be generally healthy as indicated, for example, by mobility, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002670 .
obo:WBPhenotype_0000701 a rdfs:Class ;
rdfs:label "epithelial development variant" ;
rdfs:comment "Any variation in the progression of the epithelia over time, from its formation to its mature state compared to control. This process involves autonomously generated changes in epidermal cell shape and position, and interactions with internal tissues, including the developing nervous system and body wall muscles to affect epidermal enclosure, cell intercalation, and epidermal elongation." ;
rdfs:subClassOf obo:WBPhenotype_0000619 .
obo:GO_0048580 a rdfs:Class ;
rdfs:label "regulation of post-embryonic development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000026 .
obo:WBPhenotype_0002624 a rdfs:Class ;
rdfs:label "EdU incorporation reduced"@en ;
rdfs:comment "Cells display reduced incorporation of the thymidine analogue 5-Ethynyl-2'-deoxyuridine (EdU), suggesting reduced cell proliferation. Incorporation of EdU is an indication of active DNA synthesis and thus an indication of cells proceeding through the cell cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000173 .
obo:PATO_0001707 a rdfs:Class ;
rdfs:label "behavioural active" ;
rdfs:comment "A behavioral quality of a process inhering in a bearer by virtue of the bearer's exhibiting marked activity." ;
rdfs:subClassOf obo:PATO_0002265 .
obo:CHEBI_63299 a rdfs:Class ;
rdfs:label "carbohydrate derivative" ;
rdfs:comment "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." ;
rdfs:subClassOf obo:CHEBI_78616 .
obo:WBPhenotype_0002286 a rdfs:Class ;
rdfs:label "head bend angle increased" ;
rdfs:comment "Animals exhibit an increase in the extent of the maximum flex of the most anterior portion of the animal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002284 .
obo:CHEBI_35190 a rdfs:Class ;
rdfs:label "diterpene" ;
rdfs:comment "A C20 terpene." ;
rdfs:subClassOf obo:CHEBI_35186 .
obo:CHEBI_23423 a rdfs:Class ;
rdfs:label "pseudohalogen oxoacid" ;
rdfs:subClassOf obo:CHEBI_24833 .
obo:GO_0060408 a rdfs:Class ;
rdfs:label "regulation of acetylcholine metabolic process" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ;
rdfs:subClassOf obo:GO_0033238 , obo:GO_0065007 , obo:GO_0080090 .
obo:WBPhenotype_0001987 a rdfs:Class ;
rdfs:label "acetylcholinesterase activity variant" ;
rdfs:comment "Any variation in the measured levels of acetylcholinesterase (AChE) activity compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000124 .
obo:CHEBI_39216 a rdfs:Class ;
rdfs:label "antibiotic acaricide" ;
rdfs:subClassOf obo:CHEBI_22153 , obo:CHEBI_39215 .
obo:WBPhenotype_0001096 a rdfs:Class ;
rdfs:label "protrusion at vulval region" ;
rdfs:comment "Large protrusion at the normal position of the vulva, as seen in C. elegans lin-12 null animals." ;
rdfs:subClassOf obo:WBPhenotype_0000695 .
obo:GO_0042424 a rdfs:Class ;
rdfs:label "catecholamine catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ;
rdfs:subClassOf obo:GO_0006584 , obo:GO_0019614 , obo:GO_0042402 .
obo:GO_1903353 a rdfs:Class ;
rdfs:label "regulation of nucleus organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of nucleus organization." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:CHEBI_22712 a rdfs:Class ;
rdfs:label "benzenes" ;
rdfs:comment "Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_33836 .
obo:GO_0042692 a rdfs:Class ;
rdfs:label "muscle cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0044706 a rdfs:Class ;
rdfs:label "multi-multicellular organism process" ;
rdfs:comment "A multicellular organism process which involves another multicellular organism of the same or different species." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0030705 a rdfs:Class ;
rdfs:label "cytoskeleton-dependent intracellular transport" ;
rdfs:comment "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." ;
rdfs:subClassOf obo:GO_0046907 .
obo:WBPhenotype_0000045 a rdfs:Class ;
rdfs:label "developmental delay postembryonic" ;
rdfs:comment "The developmental progression of an animal after the embryonic stage, over time, from its formation to its mature structure is delayed compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000049 , obo:WBPhenotype_0000848 .
obo:GO_0012501 a rdfs:Class ;
rdfs:label "programmed cell death" ;
rdfs:comment "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." ;
rdfs:subClassOf obo:GO_0008219 .
obo:GO_0050778 a rdfs:Class ;
rdfs:label "positive regulation of immune response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ;
rdfs:subClassOf obo:GO_0002684 , obo:GO_0048584 , obo:GO_0050776 , obo:GO_0065007 .
obo:CHEBI_59779 a rdfs:Class ;
rdfs:label "cyclic ketal" ;
rdfs:comment "A ketal in the molecule of which the ketal carbon and one or both oxygen atoms thereon are members of a ring." ;
rdfs:subClassOf obo:CHEBI_38104 , obo:CHEBI_59777 .
obo:GO_1902412 a rdfs:Class ;
rdfs:label "regulation of mitotic cytokinesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic cytokinesis." ;
rdfs:subClassOf obo:GO_0032465 , obo:GO_0065007 .
obo:CHEBI_50184 a rdfs:Class ;
rdfs:label "ion transport inhibitor" ;
rdfs:comment "A compound which inhibits the movement of an ion across an energy-transducing cell membrane." ;
rdfs:subClassOf obo:CHEBI_38632 .
obo:WBbt_0005409 a rdfs:Class ;
rdfs:label "motor neuron" ;
rdfs:comment "neuron making synapse on an effector (muscle, gland)." ;
rdfs:subClassOf obo:WBbt_0003679 .
obo:WBPhenotype_0000320 a rdfs:Class ;
rdfs:label "reduced viability after freezing" ;
rdfs:comment "Animals show a decrease in survivorship after thawing compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000141 .
obo:WBPhenotype_0000101 a rdfs:Class ;
rdfs:label "UV induced apoptosis increased" ;
rdfs:comment "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, UV irradiation, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000100 , obo:WBPhenotype_0000183 .
obo:GO_1901074 a rdfs:Class ;
rdfs:label "regulation of engulfment of apoptotic cell" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell." ;
rdfs:subClassOf obo:GO_0060099 , obo:GO_0065007 .
obo:CHEBI_29347 a rdfs:Class ;
rdfs:label "monocarboxylic acid amide" ;
rdfs:comment "A carboxamide derived from a monocarboxylic acid." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:GO_0006576 a rdfs:Class ;
rdfs:label "biogenic amine metabolic process" ;
rdfs:comment "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ;
rdfs:subClassOf obo:GO_0009308 .
obo:GO_0016877 a rdfs:Class ;
rdfs:label "ligase activity, forming carbon-sulfur bonds" ;
rdfs:comment "Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." ;
rdfs:subClassOf obo:GO_0016874 .
obo:WBPhenotype_0001307 a rdfs:Class ;
rdfs:label "reduced body bend" ;
rdfs:comment "The maximum ventral and dorsal flex of the animal is reduced compared to that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001703 .
obo:WBPhenotype_0002325 a rdfs:Class ;
rdfs:label "backward point velocity increased" ;
rdfs:comment "Animals exhibit increased velocity of backward translocation of any point along the animal's track from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002323 .
obo:CHEBI_84055 a rdfs:Class ;
rdfs:label "pentose phosphate" ;
rdfs:comment "Any phospho sugar that is the phosphate derivative of pentose." ;
rdfs:subClassOf obo:CHEBI_33447 , obo:CHEBI_63409 .
obo:WBPhenotype_0000367 a rdfs:Class ;
rdfs:label "comma arrest emb" ;
rdfs:comment "Cessation of development during the middle stage in embryogenesis of the worm in which the embryo is slightly folded within the eggshell (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000864 .
obo:GO_0000280 a rdfs:Class ;
rdfs:label "nuclear division" ;
rdfs:comment "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." ;
rdfs:subClassOf obo:GO_0048285 .
obo:CHEBI_33636 a rdfs:Class ;
rdfs:label "bicyclic compound" ;
rdfs:comment "A molecule that features two fused rings." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:WBPhenotype_0000949 a rdfs:Class ;
rdfs:label "pseudocoelom morphology variant" ;
rdfs:comment "Any variation in the appearance of the body cavity compared to control. In C. elegans , an aberrancy in the psedocoelom can involve an accumulation of fluids or fluorescent reporters." ;
rdfs:subClassOf obo:WBPhenotype_0000532 , obo:WBPhenotype_0000912 , obo:WBPhenotype_0002558 .
obo:WBPhenotype_0001510 a rdfs:Class ;
rdfs:label "neuronal cell fate specification variant" ;
rdfs:comment "Any variation in the processes that govern acquisition of neuronal cell fates compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000216 , obo:WBPhenotype_0000816 .
obo:WBPhenotype_0001257 a rdfs:Class ;
rdfs:label "cross link induced focus formation variant" ;
rdfs:comment "Variations in the generation of foci that mark sites of aberrant bonding of molecules to the DNA strand, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001256 .
obo:GO_0033206 a rdfs:Class ;
rdfs:label "meiotic cytokinesis" ;
rdfs:comment "A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells." ;
rdfs:subClassOf obo:GO_0061640 , obo:GO_1903046 .
obo:CHEBI_33408 a rdfs:Class ;
rdfs:label "pnictogen oxoacid" ;
rdfs:subClassOf obo:CHEBI_24833 , obo:CHEBI_33302 .
obo:WBPhenotype_0002247 a rdfs:Class ;
rdfs:label "copper homeostasis variant" ;
rdfs:comment "Variations in the regulation of levels, transport, and metabolism of copper ions within an organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002029 .
obo:CHEBI_33699 a rdfs:Class ;
rdfs:label "messenger RNA" ;
rdfs:comment "An RNA molecule that transfers the coding information for protein synthesis from the chromosomes to the ribosomes mRNA is formed from a DNA template by transcription. It may be a copy of a single gene or of several adjacent genes (polycistronic mRNA). On the ribosome, the sequence is converted into the programmed amino acid sequence through translation." ;
rdfs:subClassOf obo:CHEBI_33697 .
obo:GO_0045911 a rdfs:Class ;
rdfs:label "positive regulation of DNA recombination" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of DNA recombination." ;
rdfs:subClassOf obo:GO_0000018 , obo:GO_0051054 , obo:GO_0065007 .
obo:WBPhenotype_0001950 a rdfs:Class ;
rdfs:label "diplotene region organization variant" ;
rdfs:comment "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file." ;
rdfs:subClassOf obo:WBPhenotype_0001355 , obo:WBPhenotype_0001947 .
obo:PATO_0001652 a rdfs:Class ;
rdfs:label "alignment" ;
rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's spatial positioning with respect to an additional entity." ;
rdfs:subClassOf obo:PATO_0000140 .
obo:GO_0010562 a rdfs:Class ;
rdfs:label "positive regulation of phosphorus metabolic process" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0051174 , obo:GO_0065007 .
obo:GO_0009056 a rdfs:Class ;
rdfs:label "catabolic process" ;
rdfs:comment "A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." ;
rdfs:subClassOf obo:GO_0008152 .
obo:WBPhenotype_0000354 a rdfs:Class ;
rdfs:label "cell differentiation variant" ;
rdfs:comment "Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:GO_0045931 a rdfs:Class ;
rdfs:label "positive regulation of mitotic cell cycle" ;
rdfs:comment "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0045787 , obo:GO_0065007 .
obo:GO_0006417 a rdfs:Class ;
rdfs:label "regulation of translation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ;
rdfs:subClassOf obo:GO_0010608 , obo:GO_0051246 , obo:GO_0065007 .
obo:CHEBI_22256 a rdfs:Class ;
rdfs:label "adenosine phosphate" ;
rdfs:subClassOf obo:CHEBI_61296 .
obo:WBPhenotype_0002381 a rdfs:Class ;
rdfs:label "pheromone production variant" ;
rdfs:comment "Animals exhibit variations in the amount and/or quality of pheromone produced compared to control animals at a defined stage." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0002178 a rdfs:Class ;
rdfs:label "plasma membrane leaflet composition variant" ;
rdfs:comment "Any variation in the components that make up either of the two leaflets of the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002177 .
obo:GO_1904747 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic process involved in development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0051094 , obo:GO_0065007 , obo:GO_1904748 .
obo:WBPhenotype_0000052 a rdfs:Class ;
rdfs:label "maternal effect lethal emb" ;
rdfs:comment "Lethality caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis." ;
rdfs:subClassOf obo:WBPhenotype_0000050 .
obo:GO_0033157 a rdfs:Class ;
rdfs:label "regulation of intracellular protein transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0051223 , obo:GO_0065007 .
obo:WBPhenotype_0001065 a rdfs:Class ;
rdfs:label "fewer egg laying events during active" ;
rdfs:comment "Fewer egg-laying events occur within the active phase of egg laying, based on the analysis of the distribution of the log intervals of egg-laying events, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000006 , obo:WBPhenotype_0001067 .
obo:WBPhenotype_0000192 a rdfs:Class ;
rdfs:label "constitutive enzyme activity" ;
rdfs:comment "Any variation that results in the misregulation of enzymatic activity such that catalysis occurs at a constant rate regardless of physiological demand or the concentration of a substrate." ;
rdfs:subClassOf obo:WBPhenotype_0000125 .
obo:PATO_0001835 a rdfs:Class ;
rdfs:label "increased fertility" ;
rdfs:comment "A fertility which is relatively high." ;
rdfs:subClassOf obo:PATO_0000955 , obo:PATO_0002305 .
obo:PATO_0000052 a rdfs:Class ;
rdfs:label "shape" ;
rdfs:comment "A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc)." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:WBPhenotype_0000149 a rdfs:Class ;
rdfs:label "starvation induced dauer formation increased" ;
rdfs:comment "Animals are more likely to form dauers under nutrient conditions that do not induce dauer entry in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000148 .
obo:WBPhenotype_0000331 a rdfs:Class ;
rdfs:label "inhibitors of na k atpase resistant" ;
rdfs:comment "Animals fail to respond to the concentration of sodium potassium ATPase antagonists that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 .
obo:CHEBI_46345 a rdfs:Class ;
rdfs:label "5-fluorouracil" ;
rdfs:comment "A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_37143 , obo:CHEBI_67142 .
obo:WBPhenotype_0004026 a rdfs:Class ;
rdfs:label "nose touch variant" ;
rdfs:comment "Variations in the ability of an animal to respond with characteristic backward movement after a nose-on collision with an object compared to control. In C. elegans, this phenotype is usually assayed via stroking with a hair or similar fiber on the anterior most tip of the animal." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:WBPhenotype_0001025 a rdfs:Class ;
rdfs:label "hermaphrodite morphology variant" ;
rdfs:comment "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a hermaphrodite in the population, from that observed for control hermaphrodites." ;
rdfs:subClassOf obo:WBPhenotype_0001023 , obo:WBPhenotype_0002555 .
obo:CHEBI_34905 a rdfs:Class ;
rdfs:label "paraquat" ;
rdfs:comment "An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25697 .
obo:CHEBI_51721 a rdfs:Class ;
rdfs:label "alpha,beta-unsaturated ketone" ;
rdfs:comment "A ketone of general formula R1R2C=CR3‒C(=O)R4 (R4 ≠ H) or R1C≡C‒C(=O)R2 (R2 ≠ H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:GO_0010044 a rdfs:Class ;
rdfs:label "response to aluminum ion" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus." ;
rdfs:subClassOf obo:GO_0010038 .
obo:WBPhenotype_0001556 a rdfs:Class ;
rdfs:label "dauer sensillum variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000299 , obo:WBPhenotype_0001555 .
obo:WBPhenotype_0001563 a rdfs:Class ;
rdfs:label "dauer cephalic sensillum variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake." ;
rdfs:subClassOf obo:WBPhenotype_0001530 , obo:WBPhenotype_0001556 .
obo:WBPhenotype_0000978 a rdfs:Class ;
rdfs:label "spermatheca physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the spermatheca to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000929 , obo:WBPhenotype_0001197 .
obo:WBPhenotype_0002107 a rdfs:Class ;
rdfs:label "RAB-11 recycling endosome localization variant" ;
rdfs:comment "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
rdfs:subClassOf obo:WBPhenotype_0002104 .
obo:WBPhenotype_0002499 a rdfs:Class ;
rdfs:label "ectopic vulva"@en ;
rdfs:comment "Animals exhibit one or more vulvae in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0002498 .
obo:GO_0051296 a rdfs:Class ;
rdfs:label "establishment of meiotic spindle orientation" ;
rdfs:comment "Any process that set the alignment of meiotic spindle relative to other cellular structures." ;
rdfs:subClassOf obo:GO_0051294 , obo:GO_0051295 .
obo:WBPhenotype_0001344 a rdfs:Class ;
rdfs:label "organelle organization biogenesis variant" ;
rdfs:comment "Intracellular membrane bound compartments vary in shape or size from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0010002 .
obo:GO_1905083 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial translational elongation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation." ;
rdfs:subClassOf obo:GO_0045900 , obo:GO_0065007 , obo:GO_0070130 , obo:GO_1905082 .
obo:WBPhenotype_0002370 a rdfs:Class ;
rdfs:label "noxious heat avoidance defective" ;
rdfs:comment "Animals fail to execute their characteristic movements to avoid noxious heat in a manner consistent with controls." ;
rdfs:subClassOf obo:WBPhenotype_0001273 .
obo:GO_0051588 a rdfs:Class ;
rdfs:label "regulation of neurotransmitter transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:WBbt_0008608 a rdfs:Class ;
rdfs:label "B lineage cell" ;
rdfs:comment "A cell that is the B post-embryonic blast cell or is a lineal descendant of B, in male." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_0010629 a rdfs:Class ;
rdfs:label "negative regulation of gene expression" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0010558 , obo:GO_0065007 .
obo:GO_0042810 a rdfs:Class ;
rdfs:label "pheromone metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process." ;
rdfs:subClassOf obo:GO_0019748 , obo:GO_0042445 .
obo:WBPhenotype_0000781 a rdfs:Class ;
rdfs:label "body wall muscle thin filament variant" ;
rdfs:comment "Any variation in the extremely thin elongated cytoplasmic filament, usually composed principally of actin protein to form a myofilament lattice, as in muscle cells compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001889 .
obo:WBPhenotype_0002453 a rdfs:Class ;
rdfs:label "recovery pumping response to light variant" ;
rdfs:comment "Animals exhibit variations in the recovery pharyngeal pumping response to light, during which the pharyngeal pumping rate slowly increases during the 0-10 seconds afterremoval of light exposure, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002446 .
obo:WBPhenotype_0002127 a rdfs:Class ;
rdfs:label "intraflagellar transport velocity variant" ;
rdfs:comment "Animals exhibit variation rate of directed movement of organelles or molecules along microtubules in nerve cell axons, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000853 .
obo:WBbt_0007846 a rdfs:Class ;
rdfs:label "hypodermal cell" ;
rdfs:comment "primary cell type that forms the hypodermis." ;
rdfs:subClassOf obo:WBbt_0003672 .
obo:CHEBI_17359 a rdfs:Class ;
rdfs:label "sulfite" ;
rdfs:comment "A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3)." ;
rdfs:subClassOf obo:CHEBI_33482 , obo:CHEBI_48154 , obo:CHEBI_79388 .
obo:GO_1902115 a rdfs:Class ;
rdfs:label "regulation of organelle assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of organelle assembly." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0044087 , obo:GO_0065007 .
obo:GO_0060259 a rdfs:Class ;
rdfs:label "regulation of feeding behavior" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food." ;
rdfs:subClassOf obo:GO_0050795 , obo:GO_0065007 .
obo:WBPhenotype_0002387 a rdfs:Class ;
rdfs:label "supernumerary asters" ;
rdfs:comment "Dividing cells exhibit additional arrays of microtubules emanating from a spindle pole that do not connect to kinetochores, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002419 .
obo:WBPhenotype_0000385 a rdfs:Class ;
rdfs:label "sperm excess" ;
rdfs:comment "Animals produce an increased sperm population compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000670 , obo:WBPhenotype_0002552 .
obo:WBPhenotype_0002601 a rdfs:Class ;
rdfs:label "short-term associative memory phenotype"@en ;
rdfs:comment "Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the short term, compared to controls. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s)." ;
rdfs:subClassOf obo:WBPhenotype_0002564 .
obo:GO_0006406 a rdfs:Class ;
rdfs:label "mRNA export from nucleus" ;
rdfs:comment "The directed movement of mRNA from the nucleus to the cytoplasm." ;
rdfs:subClassOf obo:GO_0006405 , obo:GO_0051028 .
obo:WBPhenotype_0001274 a rdfs:Class ;
rdfs:label "organism heat hypersensitive" ;
rdfs:comment "Animals respond to heat at a lower temperature or a shorter exposure time compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001273 .
obo:GO_1900247 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translational elongation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation." ;
rdfs:subClassOf obo:GO_0006448 , obo:GO_0065007 .
obo:CHEBI_33429 a rdfs:Class ;
rdfs:label "monoatomic monoanion" ;
rdfs:subClassOf obo:CHEBI_23905 , obo:CHEBI_36830 .
obo:GO_0070265 a rdfs:Class ;
rdfs:label "obsolete necrotic cell death" ;
rdfs:comment "OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues." .
obo:WBPhenotype_0000007 a rdfs:Class ;
rdfs:label "bag of worms" ;
rdfs:comment "A worm carcass is formed with retained eggs that hatch inside." ;
rdfs:subClassOf obo:WBPhenotype_0000862 .
obo:GO_0140694 a rdfs:Class ;
rdfs:label "membraneless organelle assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle." ;
rdfs:subClassOf obo:GO_0070925 .
obo:WBPhenotype_0000412 a rdfs:Class ;
rdfs:label "octanol chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to 1-octanol as defined by control animals. In C.elegans 1-octanol is typically a repellant." ;
rdfs:subClassOf obo:WBPhenotype_0001448 , obo:WBPhenotype_0001452 .
obo:WBPhenotype_0000844 a rdfs:Class ;
rdfs:label "serotonin induced pumping variant" ;
rdfs:comment "Pharyngeal pumping is not influenced by serotonin treatment in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000024 , obo:WBPhenotype_0001232 , obo:WBPhenotype_0001285 .
obo:WBPhenotype_0001644 a rdfs:Class ;
rdfs:label "protein metabolism variant" ;
rdfs:comment "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of proteins in the organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000463 , obo:WBPhenotype_0000585 .
obo:GO_0000022 a rdfs:Class ;
rdfs:label "mitotic spindle elongation" ;
rdfs:comment "The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B." ;
rdfs:subClassOf obo:GO_0051231 , obo:GO_1903047 .
obo:GO_0060404 a rdfs:Class ;
rdfs:label "axonemal microtubule depolymerization" ;
rdfs:comment "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." ;
rdfs:subClassOf obo:GO_0007019 , obo:GO_0010938 , obo:GO_0061523 .
obo:CHEBI_37045 a rdfs:Class ;
rdfs:label "purine ribonucleoside 5'-triphosphate" ;
rdfs:subClassOf obo:CHEBI_26398 , obo:CHEBI_26400 , obo:CHEBI_37076 .
obo:CHEBI_26878 a rdfs:Class ;
rdfs:label "tertiary alcohol" ;
rdfs:comment "A tertiary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:CHEBI_36892 a rdfs:Class ;
rdfs:label "elemental fluorine" ;
rdfs:subClassOf obo:CHEBI_33434 .
obo:CHEBI_25750 a rdfs:Class ;
rdfs:label "oxime" ;
rdfs:comment "Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes." ;
rdfs:subClassOf obo:CHEBI_50860 , obo:CHEBI_51143 .
obo:WBPhenotype_0001279 a rdfs:Class ;
rdfs:label "transgene expression reduced male" ;
rdfs:comment "Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the male, that has been introduced into the organism compared to its expression in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001278 .
obo:WBPhenotype_0000529 a rdfs:Class ;
rdfs:label "cell development variant" ;
rdfs:comment "Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000518 .
obo:GO_0019722 a rdfs:Class ;
rdfs:label "calcium-mediated signaling" ;
rdfs:comment "Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions." ;
rdfs:subClassOf obo:GO_0141124 .
obo:WBPhenotype_0000123 a rdfs:Class ;
rdfs:label "enzyme expression level reduced" ;
rdfs:comment "Variations that cause a decrease in the expression level of a biological catalyst, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000120 .
obo:WBPhenotype_0002565 a rdfs:Class ;
rdfs:label "associative olfactory memory phenotype"@en ;
rdfs:comment "Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002564 .
obo:CHEBI_29699 a rdfs:Class ;
rdfs:label "tunicamycin" ;
rdfs:comment "A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_60004 .
obo:WBPhenotype_0001530 a rdfs:Class ;
rdfs:label "cephalic sensillum morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake." ;
rdfs:subClassOf obo:WBPhenotype_0000299 .
obo:GO_0010608 a rdfs:Class ;
rdfs:label "post-transcriptional regulation of gene expression" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." ;
rdfs:subClassOf obo:GO_0010468 .
obo:GO_0014042 a rdfs:Class ;
rdfs:label "positive regulation of neuron maturation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuron maturation." ;
rdfs:subClassOf obo:GO_0014041 , obo:GO_0065007 , obo:GO_1903431 .
obo:PATO_0001662 a rdfs:Class ;
rdfs:label "fragility" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer's disposition to being damaged or destroyed." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:WBPhenotype_0000502 a rdfs:Class ;
rdfs:label "right handed roller" ;
rdfs:comment "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the right-handed direction. In liquid media, wave propogation is helical rather than planar." ;
rdfs:subClassOf obo:WBPhenotype_0000645 .
obo:GO_1900087 a rdfs:Class ;
rdfs:label "positive regulation of G1/S transition of mitotic cell cycle" ;
rdfs:comment "Any signaling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901992 , obo:GO_1902808 , obo:GO_2000045 .
obo:GO_2000765 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic translation." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:CHEBI_30052 a rdfs:Class ;
rdfs:label "copper(0)" ;
rdfs:subClassOf obo:CHEBI_37404 .
obo:WBPhenotype_0002134 a rdfs:Class ;
rdfs:label "predator escape defective" ;
rdfs:comment "Animals are less successful than controls in evading predators during predator-prey interactions." ;
rdfs:subClassOf obo:WBPhenotype_0002135 .
obo:WBPhenotype_0001329 a rdfs:Class ;
rdfs:label "curly" ;
rdfs:comment "Animals exhibit a greater number of bends in their body compared to control. C. elegans posture assumes more than a single sine wave." ;
rdfs:subClassOf obo:WBPhenotype_0000001 .
obo:WBPhenotype_0000468 a rdfs:Class ;
rdfs:label "age associated fluorescence reduced" ;
rdfs:comment "Animals exhibit a decrease in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001009 .
obo:WBPhenotype_0000785 a rdfs:Class ;
rdfs:label "body part pigmentation variant" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular body part compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000278 .
obo:CHEBI_32445 a rdfs:Class ;
rdfs:label "L-cysteinium" ;
rdfs:comment "The L-enantiomer of cysteinium." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_32458 .
obo:WBPhenotype_0001113 a rdfs:Class ;
rdfs:label "P1 aster defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the P1 cell." ;
rdfs:subClassOf obo:WBPhenotype_0001110 .
obo:CHEBI_36963 a rdfs:Class ;
rdfs:label "organooxygen compound" ;
rdfs:comment "An organochalcogen compound containing at least one carbon-oxygen bond." ;
rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_36962 .
obo:WBPhenotype_0001762 a rdfs:Class ;
rdfs:label "uptake of yolk defective" ;
rdfs:comment "Yolk is not taken up by oocytes in the same manner or to the same degree as observed for control animals. This often leads to an accumulation of yolk in the pseudocoelom." ;
rdfs:subClassOf obo:WBPhenotype_0001422 , obo:WBPhenotype_0001424 .
obo:CHEBI_33273 a rdfs:Class ;
rdfs:label "polyatomic anion" ;
rdfs:comment "An anion consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_36358 .
obo:PATO_0000625 a rdfs:Class ;
rdfs:label "inverted" ;
rdfs:comment "An oriented quality inhering in a bearer by virtue of the bearer's being reversed in position, order, or condition." ;
rdfs:subClassOf obo:PATO_0000614 .
obo:GO_0048634 a rdfs:Class ;
rdfs:label "regulation of muscle organ development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of muscle development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:CHEBI_29192 a rdfs:Class ;
rdfs:label "hydrogenperoxide(1-)" ;
rdfs:subClassOf obo:CHEBI_33693 .
obo:WBPhenotype_0004007 a rdfs:Class ;
rdfs:label "periodic spicule prodding defective" ;
rdfs:comment "Males exhibit defects in the continuous prodding of spicule tips at the vulva prior to prolonged spicule insertion." ;
rdfs:subClassOf obo:WBPhenotype_0000279 .
obo:CHEBI_38104 a rdfs:Class ;
rdfs:label "oxacycle" ;
rdfs:comment "Any organic heterocyclic compound containing at least one ring oxygen atom." ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_36963 .
obo:WBPhenotype_0001043 a rdfs:Class ;
rdfs:label "interphase entry defective early emb" ;
rdfs:comment "Embryos do not enter or take longer to enter first interphase compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000740 , obo:WBPhenotype_0001100 .
obo:WBPhenotype_0000881 a rdfs:Class ;
rdfs:label "cilia mislocalized" ;
rdfs:comment "Animals exhibit variations in the placement of the microtuble-based dendritic projections in relation to the sensillum neuron, from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001526 .
obo:GO_0045732 a rdfs:Class ;
rdfs:label "positive regulation of protein catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0042176 , obo:GO_0051247 , obo:GO_0065007 .
obo:GO_0006446 a rdfs:Class ;
rdfs:label "regulation of translational initiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translational initiation." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:GO_0045836 a rdfs:Class ;
rdfs:label "positive regulation of meiotic nuclear division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of meiosis." ;
rdfs:subClassOf obo:GO_0040020 , obo:GO_0051446 , obo:GO_0051785 , obo:GO_0065007 , obo:GO_0090068 .
obo:WBls_0000041 a rdfs:Class ;
rdfs:label "adult Ce" ;
rdfs:comment "The stage that begins when a C.elegans individual is fully-developed and has reached maturity." ;
rdfs:subClassOf obo:WBls_0000104 , obo:WBls_0000816 .
obo:WBPhenotype_0008003 a rdfs:Class ;
rdfs:label "odorant imprinting variant" ;
rdfs:comment "Any variation in a learned olfactory response whereby exposure of animals to odorants during specific developmental times or physiological states results in a lasting memory compared to control. In control animals, this imprinting determines the animal's behavior upon encountering the same odorant at a later time." ;
rdfs:subClassOf obo:WBPhenotype_0001048 .
obo:GO_0030421 a rdfs:Class ;
rdfs:label "defecation" ;
rdfs:comment "The expulsion of feces from the rectum." ;
rdfs:subClassOf obo:GO_0007588 , obo:GO_0022600 .
obo:GO_0099536 a rdfs:Class ;
rdfs:label "synaptic signaling" ;
rdfs:comment "Cell-cell signaling to, from or within a synapse." ;
rdfs:subClassOf obo:GO_0007267 .
obo:WBPhenotype_0001426 a rdfs:Class ;
rdfs:label "coelomocyte endocytosis defective" ;
rdfs:comment "Fluid-phase endocytosis by coelomocytes is less frequent or efficient compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001422 , obo:WBPhenotype_0001423 .
obo:WBbt_0003681 a rdfs:Class ;
rdfs:label "pharynx" ;
rdfs:comment "the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine." ;
rdfs:subClassOf obo:WBbt_0003760 .
obo:GO_0035047 a rdfs:Class ;
rdfs:label "centrosomal and pronuclear rotation" ;
rdfs:comment "The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0048869 .
obo:GO_0006139 a rdfs:Class ;
rdfs:label "nucleobase-containing compound metabolic process" ;
rdfs:comment "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0044238 .
obo:CHEBI_27682 a rdfs:Class ;
rdfs:label "3',5'-cyclic dGMP" ;
rdfs:subClassOf obo:CHEBI_19834 .
obo:WBPhenotype_0002019 a rdfs:Class ;
rdfs:label "fewer eggs in utero" ;
rdfs:comment "Adult animals display a smaller number of eggs inside the uterus compared to controls" ;
rdfs:subClassOf obo:WBPhenotype_0000624 .
obo:GO_0061640 a rdfs:Class ;
rdfs:label "cytoskeleton-dependent cytokinesis" ;
rdfs:comment "A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton." ;
rdfs:subClassOf obo:GO_0000910 .
obo:PATO_0001241 a rdfs:Class ;
rdfs:label "physical object quality" ;
rdfs:comment "A quality which inheres in a continuant." ;
rdfs:subClassOf obo:BFO_0000019 , obo:PATO_0000001 .
obo:UBERON_0001062 a rdfs:Class ;
rdfs:label "anatomical entity" ;
rdfs:comment "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ;
rdfs:subClassOf obo:BFO_0000004 .
obo:CHEBI_38809 a rdfs:Class ;
rdfs:label "ryanodine receptor modulator" ;
rdfs:subClassOf obo:CHEBI_38808 .
obo:WBPhenotype_0001993 a rdfs:Class ;
rdfs:label "fewer gonadal sheath cells" ;
rdfs:comment "Animals exhibit fewer somatic sheath cells surrounding each gonad arm, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000399 , obo:WBPhenotype_0002174 .
obo:GO_0048870 a rdfs:Class ;
rdfs:label "cell motility" ;
rdfs:comment "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0000796 a rdfs:Class ;
rdfs:label "posterior body uncoordinated" ;
rdfs:comment "The movement of the posterior part of the worm is not coordinated with the rest of the body." ;
rdfs:subClassOf obo:WBPhenotype_0000797 .
obo:WBPhenotype_0000718 a rdfs:Class ;
rdfs:label "dosage compensation variant" ;
rdfs:comment "Variations in the process of normalizing the expression level of X-linked genes between XX and XO animals compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:CHEBI_24866 a rdfs:Class ;
rdfs:label "salt" ;
rdfs:comment "A salt is an assembly of cations and anions." ;
rdfs:subClassOf obo:CHEBI_37577 .
obo:WBPhenotype_0000035 a rdfs:Class ;
rdfs:label "larval body morphology variant" ;
rdfs:comment "Any variation in the overall structure or appearance of the animal as it progresses from hatching to adult compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000072 , obo:WBPhenotype_0000934 , obo:WBPhenotype_0002555 .
obo:WBPhenotype_0001160 a rdfs:Class ;
rdfs:label "pronuclear envelope morphology defective early emb" ;
rdfs:comment "Morphology of the pronuclear envelope is atypical in the inviable embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001159 .
obo:WBPhenotype_0002520 a rdfs:Class ;
rdfs:label "gap junction plaque morphology abnormal"@en ;
rdfs:comment "One or more cells exhibit variations in the morphology of one or more gap junction plaques, sets of associated gap junctions, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001658 .
obo:WBPhenotype_0000910 a rdfs:Class ;
rdfs:label "rectal morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the rectum compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000598 .
obo:WBPhenotype_0002152 a rdfs:Class ;
rdfs:label "mutagen induced apoptosis variant" ;
rdfs:comment "Programmed cell death of germ cells caused by exposure to physical or chemical DNA-damaging agents does not occur to the same extent as it does in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:WBPhenotype_0000316 a rdfs:Class ;
rdfs:label "touch resistant tail" ;
rdfs:comment "Failure to execute a characteristic response when struck or stroked in the posterior region. In C. elegans, animals move forward movement when struck or stroked in the posterior region, usually with a hair or similar fiber. The posterior region lies between the vulva and the tail." ;
rdfs:subClassOf obo:WBPhenotype_0000456 .
obo:GO_0042127 a rdfs:Class ;
rdfs:label "regulation of cell population proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell proliferation." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0000435 a rdfs:Class ;
rdfs:label "obsolete protein localization abnormal" ;
rdfs:comment "OBSOLETE. Any change in the subcellular localization of a protein." .
obo:GO_0007080 a rdfs:Class ;
rdfs:label "mitotic metaphase chromosome alignment" ;
rdfs:comment "A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division." ;
rdfs:subClassOf obo:GO_0051310 , obo:GO_1903047 .
obo:CHEBI_46883 a rdfs:Class ;
rdfs:label "carboxy group" ;
rdfs:subClassOf obo:CHEBI_33249 .
obo:WBPhenotype_0002033 a rdfs:Class ;
rdfs:label "lectin binding occurs" ;
rdfs:comment "Animals contain targets for exogenously applied lectins." ;
rdfs:subClassOf obo:WBPhenotype_0002031 .
obo:WBPhenotype_0000396 a rdfs:Class ;
rdfs:label "non reflexed gonad arms" ;
rdfs:comment "Gonadal arms do not bend or curve. In C. elegans gonad arms normally reflex to form a stereotypical U-shaped pattern." ;
rdfs:subClassOf obo:WBPhenotype_0000399 .
obo:WBPhenotype_0001541 a rdfs:Class ;
rdfs:label "dauer gonad arrest variant" ;
rdfs:comment "Variations in the execution of the developmentally-regulated cell cycle arrest in the gonad during the dauer stage, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000637 .
obo:WBPhenotype_0000837 a rdfs:Class ;
rdfs:label "hermaphrodite gonadal lineage variant" ;
rdfs:comment "The descendants of a gonadal precursor cell exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000836 .
obo:CHEBI_39209 a rdfs:Class ;
rdfs:label "macrolide insecticide" ;
rdfs:subClassOf obo:CHEBI_39221 .
obo:CHEBI_55373 a rdfs:Class ;
rdfs:label "isoxazoles" ;
rdfs:comment "Oxazoles in which the N and O atoms are adjacent." ;
rdfs:subClassOf obo:CHEBI_35790 .
obo:PATO_0001927 a rdfs:Class ;
rdfs:label "decreased fluorescence" ;
rdfs:comment "A fluorescence which is lower than normal." ;
rdfs:subClassOf obo:PATO_0001290 , obo:PATO_0002303 .
obo:CHEBI_77974 a rdfs:Class ;
rdfs:label "food packaging gas" ;
rdfs:comment "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." ;
rdfs:subClassOf obo:CHEBI_64047 .
obo:WBbt_0006870 a rdfs:Class ;
rdfs:label "seminal vesicle" ;
rdfs:comment "part of male gonad that holds mature sperm, made of a total of 12 nuclei." ;
rdfs:subClassOf obo:WBbt_0005729 .
obo:WBPhenotype_0002630 a rdfs:Class ;
rdfs:label "epithelial system degeneration"@en ;
rdfs:comment "Animals exhibit degeneration of the epithelial system (skin, integument or tegument), compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000600 .
obo:GO_0140352 a rdfs:Class ;
rdfs:label "export from cell" ;
rdfs:comment "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 .
obo:PATO_0000614 a rdfs:Class ;
rdfs:label "oriented" ;
rdfs:comment "A pattern where all the repeated elements are oriented in the same direction." ;
rdfs:subClassOf obo:PATO_0000440 .
obo:WBPhenotype_0001411 a rdfs:Class ;
rdfs:label "cuticle carbohydrate surface variant" ;
rdfs:comment "Animals exhibit an altered display of glycosylated proteins or lipids or altered access to glycosylated moieties along their surface from that observed in control animals of the same developmental stage. In C. elegans, variations in surface accessible glycosylated species are often revealed by altered lectin-binding from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001210 .
obo:WBPhenotype_0001228 a rdfs:Class ;
rdfs:label "alae absent" ;
rdfs:comment "Animals lack the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000202 , obo:WBPhenotype_0002558 .
obo:CHEBI_64769 a rdfs:Class ;
rdfs:label "organic cationic group" ;
rdfs:comment "A cationic group that contains carbon." ;
rdfs:subClassOf obo:CHEBI_64766 .
obo:WBPhenotype_0000870 a rdfs:Class ;
rdfs:label "obsolete mitochondria morphology variant epithelial" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0001741 a rdfs:Class ;
rdfs:label "spontaneous spicule protraction" ;
rdfs:comment "Males exhibit spicule-muscle seizures leading to inappropriately timed protraction compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002443 .
obo:WBPhenotype_0002123 a rdfs:Class ;
rdfs:label "histone acetylation variant" ;
rdfs:comment "The pattern or state of acetylation modifications of histones varies from that of controls." ;
rdfs:subClassOf obo:WBPhenotype_0001917 .
obo:WBbt_0004583 a rdfs:Class ;
rdfs:label "W cell" ;
rdfs:comment "Postembryonic neuroblast, analogous to Pn.a cells, also known as P0." ;
rdfs:subClassOf obo:WBbt_0006783 .
obo:WBPhenotype_0001361 a rdfs:Class ;
rdfs:label "chromosome condensation variant" ;
rdfs:comment "Any variation in the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0000283 a rdfs:Class ;
rdfs:label "vulva uterus connection defective" ;
rdfs:comment "Animals exhibit defects in the continuity of lumen between the vulva and uterus compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000624 .
obo:WBPhenotype_0001010 a rdfs:Class ;
rdfs:label "clear" ;
rdfs:comment "Animals appear unusually transparent when compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000527 .
obo:WBPhenotype_0000305 a rdfs:Class ;
rdfs:label "pheromone sensation variant" ;
rdfs:comment "Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that influences behavior in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:GO_1905911 a rdfs:Class ;
rdfs:label "positive regulation of dauer entry" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dauer entry." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_1905909 .
obo:GO_0042303 a rdfs:Class ;
rdfs:label "molting cycle" ;
rdfs:comment "The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc." ;
rdfs:subClassOf obo:GO_0032501 .
obo:WBPhenotype_0000636 a rdfs:Class ;
rdfs:label "neuron degeneration variant" ;
rdfs:comment "Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000612 .
obo:WBPhenotype_0001459 a rdfs:Class ;
rdfs:label "iodide chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of iodide." ;
rdfs:subClassOf obo:WBPhenotype_0001052 .
obo:WBPhenotype_0002306 a rdfs:Class ;
rdfs:label "tail movement decreased" ;
rdfs:comment "Animals exhibit a decrease in the movement of the most posterior portion of the body to a new location compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000597 , obo:WBPhenotype_0002287 .
obo:WBPhenotype_0004011 a rdfs:Class ;
rdfs:label "sperm transfer cessation defective" ;
rdfs:comment "Any variation in the retraction of spicules after all sperm that exit the seminal vesicle have been released compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000284 .
obo:CHEBI_197506 a rdfs:Class ;
rdfs:label "medium-chain fatty alcohol" ;
rdfs:comment "Any fatty alcohol with a chain length between C6 and C12." ;
rdfs:subClassOf obo:CHEBI_24026 .
obo:CHEBI_17561 a rdfs:Class ;
rdfs:label "L-cysteine" ;
rdfs:comment "An optically active form of cysteine having L-configuration." ;
rdfs:subClassOf obo:CHEBI_15356 , obo:CHEBI_15705 , obo:CHEBI_26650 , obo:CHEBI_83813 .
obo:CHEBI_18179 a rdfs:Class ;
rdfs:label "phosphoinositide" ;
rdfs:comment "Any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol." ;
rdfs:subClassOf obo:CHEBI_28874 .
obo:WBbt_0007815 a rdfs:Class ;
rdfs:label "hermaphrodite somatic gonadal cell" ;
rdfs:comment "somatic (not germline) cell of the hermaphrodite gonad." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBPhenotype_0002473 a rdfs:Class ;
rdfs:label "autophagy block" ;
rdfs:comment "Animals fail to undergo the cellular catabolic process in which cells digest parts of their own cytoplasm." ;
rdfs:subClassOf obo:WBPhenotype_0002283 .
obo:GO_0050803 a rdfs:Class ;
rdfs:label "regulation of synapse structure or activity" ;
rdfs:comment "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ;
rdfs:subClassOf obo:GO_0065008 .
obo:WBPhenotype_0000755 a rdfs:Class ;
rdfs:label "L1 L2 molt defect" ;
rdfs:comment "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L1 to L2 transition." ;
rdfs:subClassOf obo:WBPhenotype_0000638 .
obo:CHEBI_37415 a rdfs:Class ;
rdfs:label "alpha-amanitin" ;
rdfs:comment "A heterodetic cyclic peptide consisting of eight amino acid residues and containing a thioether bridge between a cysteine and a tryptophan residue. It is found in a number of poisonous mushrooms, including Amanita phalloides (the death cap), Galerina marginata, and and Conocybe filaris." ;
rdfs:subClassOf obo:CHEBI_24533 .
obo:WBPhenotype_0000220 a rdfs:Class ;
rdfs:label "vulva cell fate specification variant" ;
rdfs:comment "Any aberrancy in the processes that govern acquisition of vulval cell fates compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000216 , obo:WBPhenotype_0000699 .
obo:GO_1902904 a rdfs:Class ;
rdfs:label "negative regulation of supramolecular fiber organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1902903 .
obo:CHEBI_36828 a rdfs:Class ;
rdfs:label "pseudohalide anion" ;
rdfs:subClassOf obo:CHEBI_36829 .
obo:WBPhenotype_0000428 a rdfs:Class ;
rdfs:label "no adult cuticle" ;
rdfs:comment "Adult animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000427 .
obo:PATO_0001301 a rdfs:Class ;
rdfs:label "chromatic property" ;
rdfs:comment "An optical quality that is the mixture, purity or pattern of wavelengths of light perceived by the observer." ;
rdfs:subClassOf obo:PATO_0001300 .
obo:WBPhenotype_0000707 a rdfs:Class ;
rdfs:label "pharyngeal development variant" ;
rdfs:comment "Variations in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure compared to control. In C. elegans the pharynx is divided into the anterior and posterior regions. The anterior region includes the corpus (procorpus and metacorpus - first bulb) and the posterior region includes the isthmus and terminal bulb (second bulb)." ;
rdfs:subClassOf obo:WBPhenotype_0000617 .
obo:CHEBI_64237 a rdfs:Class ;
rdfs:label "EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor" ;
rdfs:comment "An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins." ;
rdfs:subClassOf obo:CHEBI_76816 .
obo:WBPhenotype_0000569 a rdfs:Class ;
rdfs:label "axon varicosities" ;
rdfs:comment "Animals display markedly swollen areas along their axons, which are larger than synaptic varicosities in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000568 .
obo:WBPhenotype_0001820 a rdfs:Class ;
rdfs:label "bordering" ;
rdfs:comment "Animals tend to accumulate at the thickest part of the bacterial lawn." ;
rdfs:subClassOf obo:WBPhenotype_0000662 , obo:WBPhenotype_0001291 .
obo:GO_0010623 a rdfs:Class ;
rdfs:label "programmed cell death involved in cell development" ;
rdfs:comment "The activation of endogenous cellular processes that result in the death of a cell as part of its development." ;
rdfs:subClassOf obo:GO_0012501 , obo:GO_0048869 .
obo:WBPhenotype_0001790 a rdfs:Class ;
rdfs:label "thermoreceptor currents absent" ;
rdfs:comment "Cooling or warming evoked changes in membrane currents are not observed." ;
rdfs:subClassOf obo:WBPhenotype_0002563 .
obo:WBls_0000806 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during 1.5-fold embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the 1.5-fold embryo life stage" ;
rdfs:subClassOf obo:WBls_0000805 .
obo:CHEBI_33670 a rdfs:Class ;
rdfs:label "heteromonocyclic compound" ;
rdfs:subClassOf obo:CHEBI_33661 , obo:CHEBI_5686 .
obo:GO_0042981 a rdfs:Class ;
rdfs:label "regulation of apoptotic process" ;
rdfs:comment "Any process that modulates the occurrence or rate of cell death by apoptotic process." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0065007 .
obo:WBPhenotype_0000294 a rdfs:Class ;
rdfs:label "intestine dark" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that decrease the transparency/translucency of the intestine." ;
rdfs:subClassOf obo:WBPhenotype_0000293 .
obo:CL_0000413 a rdfs:Class ;
rdfs:label "haploid cell" ;
rdfs:comment "A cell whose nucleus contains a single haploid genome." ;
rdfs:subClassOf obo:CL_0000000 .
obo:WBPhenotype_0001831 a rdfs:Class ;
rdfs:label "intestinal microvilli variant" ;
rdfs:comment "Any variation in the formation of intestinal microvilli. Microvilli are actin-based cellular structures that form plasma membrane projections into the extracellular space and whose specialized shape provides increased cellular surface area. Microvilli are a crucial component of the terminal differentiation process for many epithelial cell types, usually ones that play an absorptive or filtering role." ;
rdfs:subClassOf obo:WBPhenotype_0000705 .
obo:WBPhenotype_0002163 a rdfs:Class ;
rdfs:label "oxygen consumption decreased" ;
rdfs:comment "Animals exhibit a decreased rate of oxygen utilization compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002141 .
obo:PATO_0000297 a rdfs:Class ;
rdfs:label "arrested" ;
rdfs:comment "A quality of a process which ends earlier than the natural end time or reference process." ;
rdfs:subClassOf obo:PATO_0002052 , obo:PATO_0002324 .
obo:CHEBI_155837 a rdfs:Class ;
rdfs:label "tripeptide zwitterion" ;
rdfs:comment "A peptide zwitterion obtained from the tranfer of a proton from the carboxy group to the amino group of any tripeptide. It contains an equal number of positively-charged and negatively-charged functional groups. Major structure at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_60466 .
obo:WBPhenotype_0001806 a rdfs:Class ;
rdfs:label "protein stabilization variant" ;
rdfs:comment "Any variation in the ability of a protein to resist disintegration via chemical or physical modifications compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001644 .
obo:WBPhenotype_0000268 a rdfs:Class ;
rdfs:label "P cell cleavage delayed" ;
rdfs:comment "Any variation that causes a delay in the stereotypical cleavage pattern of the P cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000267 .
obo:CHEBI_50893 a rdfs:Class ;
rdfs:label "azaarene" ;
rdfs:subClassOf obo:CHEBI_33833 , obo:CHEBI_38101 .
obo:GO_0019098 a rdfs:Class ;
rdfs:label "reproductive behavior" ;
rdfs:comment "The specific behavior of an organism that is associated with reproduction." ;
rdfs:subClassOf obo:GO_0007610 , obo:GO_0048609 .
obo:WBPhenotype_0000899 a rdfs:Class ;
rdfs:label "epithelial cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of epithelial cells compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002108 .
obo:WBPhenotype_0002061 a rdfs:Class ;
rdfs:label "chromosome decondensation variant" ;
rdfs:comment "Any variation in the progressive decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:CHEBI_71300 a rdfs:Class ;
rdfs:label "EC 2.* (transferase) inhibitor" ;
rdfs:comment "An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)" ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:CHEBI_75771 a rdfs:Class ;
rdfs:label "mouse metabolite" ;
rdfs:comment "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." ;
rdfs:subClassOf obo:CHEBI_75768 .
obo:WBPhenotype_0001520 a rdfs:Class ;
rdfs:label "posterior neuron migration variant" ;
rdfs:comment "Any variation in the orderly movement of neurons along the posterior axis of the animal(abolished, misdirected or incomplete) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001140 , obo:WBPhenotype_0001519 .
obo:WBPhenotype_0002500 a rdfs:Class ;
rdfs:label "ectopic cleavage furrow"@en ;
rdfs:comment "One or more cells exhibit one or more cleavage furrows in locations not normally found in control cells." ;
rdfs:subClassOf obo:WBPhenotype_0002410 .
obo:CHEBI_53121 a rdfs:Class ;
rdfs:label "adenosine A2A receptor antagonist" ;
rdfs:comment "An antagonist at the A2A receptor." ;
rdfs:subClassOf obo:CHEBI_71232 .
obo:CHEBI_33216 a rdfs:Class ;
rdfs:label "bisphenol A" ;
rdfs:comment "A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_22901 .
obo:GO_0050684 a rdfs:Class ;
rdfs:label "regulation of mRNA processing" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903311 .
obo:CHEBI_33917 a rdfs:Class ;
rdfs:label "aldohexose" ;
rdfs:comment "A hexose with a (potential) aldehyde group at one end." ;
rdfs:subClassOf obo:CHEBI_15693 , obo:CHEBI_18133 .
obo:GO_1901524 a rdfs:Class ;
rdfs:label "regulation of mitophagy" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of macromitophagy." ;
rdfs:subClassOf obo:GO_0016241 , obo:GO_0065007 , obo:GO_1903146 .
obo:GO_0048086 a rdfs:Class ;
rdfs:label "negative regulation of developmental pigmentation" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ;
rdfs:subClassOf obo:GO_0048070 , obo:GO_0048519 , obo:GO_0065007 .
obo:GO_0046833 a rdfs:Class ;
rdfs:label "positive regulation of RNA export from nucleus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0032241 , obo:GO_0046824 , obo:GO_0046831 , obo:GO_0065007 .
obo:PATO_0001375 a rdfs:Class .
obo:CHEBI_39220 a rdfs:Class ;
rdfs:label "avermectin pesticide" ;
rdfs:subClassOf obo:CHEBI_39221 .
obo:WBPhenotype_0001701 a rdfs:Class ;
rdfs:label "spastic locomotion" ;
rdfs:comment "Animals exhibit uncharacteristic muscle contractions during the process by which they travel from one location to another." ;
rdfs:subClassOf obo:WBPhenotype_0004017 .
obo:GO_2000807 a rdfs:Class ;
rdfs:label "regulation of synaptic vesicle clustering" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of synaptic vesicle clustering." ;
rdfs:subClassOf obo:GO_0032879 , obo:GO_0065007 .
obo:WBPhenotype_0002226 a rdfs:Class ;
rdfs:label "cobalt hypersensitive" ;
rdfs:comment "Animals respond to cobalt at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000591 , obo:WBPhenotype_0001918 .
obo:CHEBI_37948 a rdfs:Class ;
rdfs:label "oxaspiro compound" ;
rdfs:comment "A spiro compound in which at least one of the cyclic components is an oxygen heterocyle." ;
rdfs:subClassOf obo:CHEBI_33599 .
obo:CHEBI_35337 a rdfs:Class ;
rdfs:label "central nervous system stimulant" ;
rdfs:comment "Any drug that enhances the activity of the central nervous system." ;
rdfs:subClassOf obo:CHEBI_35470 .
obo:WBPhenotype_0001350 a rdfs:Class ;
rdfs:label "protein phosphorylation increased" ;
rdfs:comment "Animals exhibit higher levels of protein phosphorylation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001349 .
obo:WBPhenotype_0000171 a rdfs:Class ;
rdfs:label "cell proliferation variant" ;
rdfs:comment "Any aberrancy in the processes that govern expansion of cell populations compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:CHEBI_30751 a rdfs:Class ;
rdfs:label "formic acid" ;
rdfs:comment "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects." ;
rdfs:subClassOf obo:CHEBI_25384 .
obo:CHEBI_24782 a rdfs:Class ;
rdfs:label "imide" ;
rdfs:subClassOf obo:CHEBI_33257 .
obo:WBPhenotype_0002665 a rdfs:Class ;
rdfs:label "RNA condensate variant"@en ;
rdfs:comment "Any variation in the properties of an RNA condensate within a cell or cellular compartment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002664 .
obo:WBbt_0005747 a rdfs:Class ;
rdfs:label "reproductive system" ;
rdfs:subClassOf obo:WBbt_0005746 .
obo:CHEBI_75763 a rdfs:Class ;
rdfs:label "eukaryotic metabolite" ;
rdfs:comment "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:WBPhenotype_0000851 a rdfs:Class ;
rdfs:label "ciliated neuron physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the ciliated neuron to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002563 .
obo:WBPhenotype_0002216 a rdfs:Class ;
rdfs:label "pattern antibody staining variant" ;
rdfs:comment "Any variation in the cellular or subcellular distribution of a gene product, as detected by antibody staining, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000424 .
obo:WBPhenotype_0002253 a rdfs:Class ;
rdfs:label "22G RNA expression reduced" ;
rdfs:comment "Animals exhibit lowered levels of any or all of the clades of 22G RNA molecules, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:WBPhenotype_0000573 a rdfs:Class ;
rdfs:label "obsolete neuronal branching variant" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0002350 a rdfs:Class ;
rdfs:label "hydrogen peroxide levels increased" ;
rdfs:comment "Animals exhibit increases in steady-state levels of hydrogen peroxide (H2O2) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002003 , obo:WBPhenotype_0002238 .
obo:CHEBI_33284 a rdfs:Class ;
rdfs:label "nutrient" ;
rdfs:comment "A nutrient is a food component that an organism uses to survive and grow." ;
rdfs:subClassOf obo:CHEBI_78295 .
obo:WBPhenotype_0001107 a rdfs:Class ;
rdfs:label "spindle rotation defective early emb" ;
rdfs:comment "Rotation of the embryonic spindle is aberrant." ;
rdfs:subClassOf obo:WBPhenotype_0001102 , obo:WBPhenotype_0002417 .
obo:WBPhenotype_0001682 a rdfs:Class ;
rdfs:label "organism UV resistant" ;
rdfs:comment "Organisms respond to UV at a higer dose or a longer exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000143 .
obo:GO_0045900 a rdfs:Class ;
rdfs:label "negative regulation of translational elongation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." ;
rdfs:subClassOf obo:GO_0006448 , obo:GO_0017148 , obo:GO_0065007 .
obo:WBPhenotype_0000037 a rdfs:Class ;
rdfs:label "egg morphology variant" ;
rdfs:comment "Any variation in the overall structure or appearance of fertilized oocytes that are laid compared to those laid by control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000934 .
a rdfs:Class .
obo:GO_1904093 a rdfs:Class ;
rdfs:label "negative regulation of autophagic cell death" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death." ;
rdfs:subClassOf obo:GO_0043069 , obo:GO_0065007 , obo:GO_1904092 .
obo:GO_0007054 a rdfs:Class ;
rdfs:label "spindle assembly involved in male meiosis I" ;
rdfs:comment "The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0007053 , obo:GO_0051225 .
obo:CHEBI_32456 a rdfs:Class ;
rdfs:label "cysteinate(1-)" ;
rdfs:comment "A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group." ;
rdfs:subClassOf obo:CHEBI_33558 , obo:CHEBI_63470 .
obo:CHEBI_35488 a rdfs:Class ;
rdfs:label "central nervous system depressant" ;
rdfs:comment "A loosely defined group of drugs that tend to reduce the activity of the central nervous system." ;
rdfs:subClassOf obo:CHEBI_35470 .
obo:GO_0007631 a rdfs:Class ;
rdfs:label "feeding behavior" ;
rdfs:comment "Behavior associated with the intake of food." ;
rdfs:subClassOf obo:GO_0007610 .
obo:WBPhenotype_0002072 a rdfs:Class ;
rdfs:label "carbohydrate metabolism variant" ;
rdfs:comment "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of carbohydrates within the organism or cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:GO_0043069 a rdfs:Class ;
rdfs:label "negative regulation of programmed cell death" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0048523 , obo:GO_0065007 .
obo:CHEBI_60330 a rdfs:Class ;
rdfs:label "2-methyl-2-(methylsulfanyl)propanal oxime" ;
rdfs:comment "The oxime resulting from the formal condensation of 2-methyl-2-(methylsulfanyl)propanal with hydroxylamine. Addition of the oxime group to methyl isocyanate forms the final step in the synthesis of the systemic insecticide aldicarb." ;
rdfs:subClassOf obo:CHEBI_82744 , obo:CHEBI_86315 .
obo:WBPhenotype_0000324 a rdfs:Class ;
rdfs:label "short" ;
rdfs:comment "Animals exhibit a decreased body length compared to control animals of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0000229 .
obo:WBbt_0005212 a rdfs:Class ;
rdfs:label "dorso-rectal ganglion" ;
rdfs:comment "the ganglion that lies above and behind the rectum in the tail, in close continuity with the anal hypodermal ridge. It contains 3 neuron cell bodies (DVA, DVB and DVC) that send their neuronal processes into the ventral nerve cord via dorso-rectal commissures that encircle the anus. The ganglion contains no local neuropil in the hermaphrodite. In the adult male tail, this ganglion gains additional neurons and some local neuropil." ;
rdfs:subClassOf obo:WBbt_0006977 .
obo:PATO_0002325 a rdfs:Class ;
rdfs:label "onset quality" ;
rdfs:comment "The temporal relation between the start of the process with respect to a reference process." ;
rdfs:subClassOf obo:PATO_0002323 .
obo:WBPhenotype_0002022 a rdfs:Class ;
rdfs:label "no synaptic spike frequency" ;
rdfs:comment "Calcium transients at presynaptic regions do not occur." ;
rdfs:subClassOf obo:WBPhenotype_0002021 .
obo:WBPhenotype_0001124 a rdfs:Class ;
rdfs:label "ABa ABp EMS synchronous division early emb" ;
rdfs:comment "EMS divides at the same time that ABa and ABp divide." ;
rdfs:subClassOf obo:WBPhenotype_0001120 .
obo:WBls_0000824 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during larval molt"@en ;
rdfs:comment "C. elegans life stage that occurs during a larval molt" ;
rdfs:subClassOf obo:WBls_0000817 .
obo:WBbt_0004432 a rdfs:Class ;
rdfs:label "P7.pppp" ;
rdfs:comment "Posterior daughter cell of P7.ppp, fuses into hermaphrodite vulA syncytium." ;
rdfs:subClassOf obo:WBbt_0008289 .
obo:GO_0042327 a rdfs:Class ;
rdfs:label "positive regulation of phosphorylation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." ;
rdfs:subClassOf obo:GO_0042325 , obo:GO_0045937 , obo:GO_0065007 .
obo:GO_0045702 a rdfs:Class ;
rdfs:label "positive regulation of spermatid nuclear differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0045597 , obo:GO_0045700 , obo:GO_0065007 , obo:GO_2000243 .
obo:WBPhenotype_0000967 a rdfs:Class ;
rdfs:label "obsolete male tail spike" ;
rdfs:comment "OBSOLETE." .
obo:PATO_0001583 a rdfs:Class ;
rdfs:label "decreased variability" ;
rdfs:comment "A variability which is relatively low." ;
rdfs:subClassOf obo:PATO_0001227 , obo:PATO_0002301 .
obo:GO_0046822 a rdfs:Class ;
rdfs:label "regulation of nucleocytoplasmic transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0065007 .
obo:CHEBI_29922 a rdfs:Class ;
rdfs:label "sulfo group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:RO_0018037 a rdf:Property ;
rdfs:label "is substituent group from" ;
rdfs:range .
obo:GO_0044784 a rdfs:Class ;
rdfs:label "metaphase/anaphase transition of cell cycle" ;
rdfs:comment "The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle." ;
rdfs:subClassOf obo:GO_0033045 , obo:GO_0044770 .
obo:WBPhenotype_0001842 a rdfs:Class ;
rdfs:label "drug withdrawal response variant" ;
rdfs:comment "Any variation in the state or activity of an organism as a result of abrupt discontinuation or decreased dosage of a drug, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0001374 a rdfs:Class ;
rdfs:label "pronuclear nuclear appearance variant emb" ;
rdfs:comment "The shape and size of nuclei as well as the distribution of nucleoporins are strongly affected." ;
rdfs:subClassOf obo:WBPhenotype_0000764 .
obo:WBPhenotype_0000595 a rdfs:Class ;
rdfs:label "head behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of the head in response to external or internal stimuli compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000580 .
obo:CHEBI_33692 a rdfs:Class ;
rdfs:label "hydrides" ;
rdfs:comment "Hydrides are chemical compounds of hydrogen with other chemical elements." ;
rdfs:subClassOf obo:CHEBI_33608 , obo:CHEBI_37577 .
obo:WBPhenotype_0000892 a rdfs:Class ;
rdfs:label "hermaphrodite germline proliferation variant" ;
rdfs:comment "Nuclear divisions in the germ line of hermaphrodites are either expanded are reduced compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000823 .
obo:CHEBI_50326 a rdfs:Class ;
rdfs:label "sulfanylmethyl group" ;
rdfs:subClassOf obo:CHEBI_50325 .
obo:CHEBI_33238 a rdfs:Class ;
rdfs:label "monoatomic entity" ;
rdfs:comment "A monoatomic entity is a molecular entity consisting of a single atom." ;
rdfs:subClassOf obo:CHEBI_33259 .
obo:WBPhenotype_0002141 a rdfs:Class ;
rdfs:label "oxygen consumption variant" ;
rdfs:comment "Variations in the process of gaseous oxygen intake between an organism and its environment compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001835 .
obo:GO_0065003 a rdfs:Class ;
rdfs:label "protein-containing complex assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0043933 .
obo:WBPhenotype_0001219 a rdfs:Class ;
rdfs:label "cell survival sexually dimorphic increased" ;
rdfs:comment "Animals exhibit a decrease in the rate or extent of programmed cell death and thus an increase in cell survival, as it pertains to a sex-specific feature, compared to control populations." ;
rdfs:subClassOf obo:WBPhenotype_0001218 .
obo:WBPhenotype_0001255 a rdfs:Class ;
rdfs:label "wing cilia bulbous" ;
rdfs:comment "Animals exhibit wing cell sensory cilia that are truncated and swollen unlike that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001248 .
obo:WBPhenotype_0000018 a rdfs:Class ;
rdfs:label "pharyngeal pumping increased" ;
rdfs:comment "The contraction and relaxation movements of the pharynx occur at a greater frequency compared to that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001006 .
obo:PATO_0000488 a rdfs:Class ;
rdfs:label "unresponsive to" ;
rdfs:comment "A response quality inhering in a bearer by virtue of the bearer's lack of reaction to a stimulus or an agent." ;
rdfs:subClassOf obo:PATO_0000077 .
obo:WBPhenotype_0002549 a rdfs:Class ;
rdfs:label "increased frequency of spontaneous reversal initiation"@en ;
rdfs:comment "Animals exhibit an increase in the rate at which spontaneous backward locomotion is initiated compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001506 .
obo:WBPhenotype_0000143 a rdfs:Class ;
rdfs:label "organism UV response variant" ;
rdfs:comment "Animals exhibit variations in their response to ultraviolet radiation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 , obo:WBPhenotype_0001897 .
obo:WBPhenotype_0001295 a rdfs:Class ;
rdfs:label "body twisted" ;
rdfs:comment "Any portion of the animal, between the head and the tail, appears distorted, usually due to uncharacteristic winding." ;
rdfs:subClassOf obo:WBPhenotype_0000072 .
obo:WBPhenotype_0002209 a rdfs:Class ;
rdfs:label "hook development variant" ;
rdfs:comment "Any variation in the development of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating." ;
rdfs:subClassOf obo:WBPhenotype_0000624 , obo:WBPhenotype_0001297 .
obo:GO_1903745 a rdfs:Class ;
rdfs:label "negative regulation of nematode pharyngeal pumping" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of nematode pharyngeal pumping." ;
rdfs:subClassOf obo:GO_0043051 , obo:GO_0065007 , obo:GO_1903999 .
obo:GO_0006351 a rdfs:Class ;
rdfs:label "DNA-templated transcription" ;
rdfs:comment "The synthesis of an RNA transcript from a DNA template." ;
rdfs:subClassOf obo:GO_0032774 .
obo:WBPhenotype_0000666 a rdfs:Class ;
rdfs:label "ovulation variant" ;
rdfs:comment "Any variation that disrupts the release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:GO_0032351 a rdfs:Class ;
rdfs:label "negative regulation of hormone metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0032350 , obo:GO_0065007 .
obo:GO_0009894 a rdfs:Class ;
rdfs:label "regulation of catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:WBPhenotype_0002676 a rdfs:Class ;
rdfs:label "hypersensitive to allyl alcohol"@en ;
rdfs:comment "Animals respond to allyl alcohol at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001918 .
obo:WBPhenotype_0002024 a rdfs:Class ;
rdfs:label "cell body spike frequency variant" ;
rdfs:comment "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed in cell bodies, which are independent of presynaptic inputs." ;
rdfs:subClassOf obo:WBPhenotype_0002023 .
obo:WBPhenotype_0001032 a rdfs:Class ;
rdfs:label "larval behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of a larvae in response to external or internal stimuli compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000819 .
obo:WBPhenotype_0001803 a rdfs:Class ;
rdfs:label "endosome biogenesis variant" ;
rdfs:comment "Animals exhibit variations in the formation or disassembly of membrane bound organelles that traffic material between the plasma membrane and internal compartments of the cell, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001344 .
obo:GO_0140253 a rdfs:Class ;
rdfs:label "cell-cell fusion" ;
rdfs:comment "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0000266 a rdfs:Class ;
rdfs:label "cell cleavage variant" ;
rdfs:comment "Variations that disrupt stereotypical cleavage patterns (such as cleavage rate, division axes or asymmetric division) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:WBPhenotype_0001217 a rdfs:Class ;
rdfs:label "germ cell mitosis metaphase to anaphase transition block" ;
rdfs:comment "Germ line cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001215 , obo:WBPhenotype_0001497 .
obo:CHEBI_17326 a rdfs:Class ;
rdfs:label "nucleoside 5'-triphoshate" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25608 .
obo:WBPhenotype_0002090 a rdfs:Class ;
rdfs:label "endosome morphology variant" ;
rdfs:comment "Any variation in the form or composition of membrane bound organelles, known as endosomes, that traffic material between the plasma membrane and internal compartments of the cell, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001323 .
obo:GO_0016049 a rdfs:Class ;
rdfs:label "cell growth" ;
rdfs:comment "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0040007 .
obo:WBPhenotype_0000543 a rdfs:Class ;
rdfs:label "forward kinker" ;
rdfs:comment "Forward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves forward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000002 .
obo:GO_0023061 a rdfs:Class ;
rdfs:label "signal release" ;
rdfs:comment "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." ;
rdfs:subClassOf obo:GO_0032940 .
obo:CHEBI_51074 a rdfs:Class ;
rdfs:label "(R)-colchicine" ;
rdfs:comment "A colchicine that has (R)-configuration." ;
rdfs:subClassOf obo:CHEBI_23359 .
obo:WBPhenotype_0000625 a rdfs:Class ;
rdfs:label "synaptogenesis variant" ;
rdfs:comment "Any variation in the biosynthesis of a synapse compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000623 .
obo:WBbt_0008611 a rdfs:Class ;
rdfs:label "AB lineage cell" ;
rdfs:comment "A cell that is the AB blast cell or is a lineal descendant of AB." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_0140047 a rdfs:Class ;
rdfs:label "specialized extracellular matrix" ;
rdfs:comment "Species or cell-type specific extracellular matrices that are different from the two main types of extracellular matrices: the interstitial ECM and the basement membrane ECM in metazoa." ;
rdfs:subClassOf obo:GO_0031012 .
obo:WBPhenotype_0000518 a rdfs:Class ;
rdfs:label "development phenotype" ;
rdfs:comment "Variations in the progression of an integrated living unit (a cell, tissue, organ or organism) over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000519 .
obo:WBls_0000813 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during blastula embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the blastula embryo life stage" ;
rdfs:subClassOf obo:WBls_0000812 .
obo:WBPhenotype_0002398 a rdfs:Class ;
rdfs:label "starved L1 larvae aggregation variant" ;
rdfs:comment "Animals exhibit variations in the aggregation behavior of starved L1 larvae, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001032 .
obo:WBPhenotype_0000744 a rdfs:Class ;
rdfs:label "transgene induced cosuppression variant" ;
rdfs:comment "Animals exhibit variations in the silencing of endogenous genes after introduction of repetitive exogenous cognate DNA compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002063 .
obo:WBPhenotype_0002511 a rdfs:Class ;
rdfs:label "fewer glutamatergic neurons"@en ;
rdfs:comment "Animals exhibit fewer glutamatergic neurons compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002510 .
obo:CHEBI_33666 a rdfs:Class ;
rdfs:label "polycyclic hydrocarbon" ;
rdfs:subClassOf obo:CHEBI_33663 , obo:CHEBI_35294 .
obo:GO_1902104 a rdfs:Class ;
rdfs:label "positive regulation of metaphase/anaphase transition of meiotic cell cycle" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901995 , obo:GO_1902101 , obo:GO_1902102 , obo:GO_1905134 .
obo:GO_0072710 a rdfs:Class ;
rdfs:label "response to hydroxyurea" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus." ;
rdfs:subClassOf obo:GO_1901698 .
obo:WBbt_0006749 a rdfs:Class ;
rdfs:label "nerve ring" ;
rdfs:comment "the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:CHEBI_167559 a rdfs:Class ;
rdfs:label "glycan" ;
rdfs:comment "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." ;
rdfs:subClassOf obo:CHEBI_78616 .
obo:GO_0051253 a rdfs:Class ;
rdfs:label "negative regulation of RNA metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." ;
rdfs:subClassOf obo:GO_0010605 , obo:GO_0045934 , obo:GO_0051252 , obo:GO_0065007 .
obo:GO_0070124 a rdfs:Class ;
rdfs:label "mitochondrial translational initiation" ;
rdfs:comment "The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA." ;
rdfs:subClassOf obo:GO_0006413 .
obo:CHEBI_35552 a rdfs:Class ;
rdfs:label "heterocyclic organic fundamental parent" ;
rdfs:subClassOf obo:CHEBI_33245 .
obo:WBPhenotype_0001303 a rdfs:Class ;
rdfs:label "extra and ectopic cell" ;
rdfs:comment "Animals have one or more extra cells of a particular type, which are present in places they are normally not found, when compared to the number and location of these cells in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002175 , obo:WBPhenotype_0002493 .
obo:WBPhenotype_0002279 a rdfs:Class ;
rdfs:label "fat associated body size decreased" ;
rdfs:comment "Animals exhibit a decrease in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining." ;
rdfs:subClassOf obo:WBPhenotype_0001901 .
obo:CHEBI_38313 a rdfs:Class ;
rdfs:label "diazines" ;
rdfs:comment "Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure)." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:WBPhenotype_0002138 a rdfs:Class ;
rdfs:label "acquired thermotolerance variant" ;
rdfs:comment "Animals are altered in their capacity to survive a normally lethal temperature treatment as a consequence of pretreatment at an elevated but sublethal temperature." ;
rdfs:subClassOf obo:WBPhenotype_0000146 .
obo:WBPhenotype_0001285 a rdfs:Class ;
rdfs:label "induced pharyngeal pumping variant" ;
rdfs:comment "Pharyngeal pumping is not influenced by treatment with specific compounds (eg: serotonin) in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001006 .
obo:CHEBI_35942 a rdfs:Class ;
rdfs:label "neurotransmitter agent" ;
rdfs:comment "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_52210 .
obo:WBPhenotype_0001381 a rdfs:Class ;
rdfs:label "anoxia resistant" ;
rdfs:comment "Animals fail to respond to trace amounts of oxygen that elicit a response in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002424 .
obo:GO_0030968 a rdfs:Class ;
rdfs:label "endoplasmic reticulum unfolded protein response" ;
rdfs:comment "The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation." ;
rdfs:subClassOf obo:GO_0034976 , obo:GO_0035556 .
obo:WBPhenotype_0000584 a rdfs:Class ;
rdfs:label "synaptic transmission variant" ;
rdfs:comment "Any variation in the process of communication across a synapse between a neuron and a target cell (neuron, muscle, or secretory cell) compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002020 .
obo:CHEBI_47857 a rdfs:Class ;
rdfs:label "ureas" ;
rdfs:subClassOf obo:CHEBI_33256 .
obo:CHEBI_50860 a rdfs:Class ;
rdfs:label "organic molecular entity" ;
rdfs:comment "Any molecular entity that contains carbon." ;
rdfs:subClassOf obo:CHEBI_33582 .
obo:WBPhenotype_0001208 a rdfs:Class ;
rdfs:label "RNAi resistant" ;
rdfs:comment "Animals show reduced susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:WBPhenotype_0001660 a rdfs:Class ;
rdfs:label "loss of asymmetry ASE" ;
rdfs:comment "The two morphologically bilaterally symmetric gustatory neurons ASE left (ASEL) and ASE right (ASER) fail to undergo a left/right asymmetric diversification in cell fate." ;
rdfs:subClassOf obo:WBPhenotype_0001510 , obo:WBPhenotype_0001512 .
obo:WBPhenotype_0001266 a rdfs:Class ;
rdfs:label "genetic pathway activation variant" ;
rdfs:comment "Any variation in triggering of the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000074 .
obo:GO_0035966 a rdfs:Class ;
rdfs:label "response to topologically incorrect protein" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." ;
rdfs:subClassOf obo:GO_0006950 .
obo:WBPhenotype_0000134 a rdfs:Class ;
rdfs:label "gene expression level reduced" ;
rdfs:comment "Animals exhibit a decrease in the intensity of expression of a gene product compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002575 .
obo:WBPhenotype_0001402 a rdfs:Class ;
rdfs:label "connected mitochondria" ;
rdfs:comment "Mitochondria are interconnected by thin tubules of mitochondrial inner or outer membrane." ;
rdfs:subClassOf obo:WBPhenotype_0001401 .
obo:CHEBI_17688 a rdfs:Class ;
rdfs:label "(S)-nicotine" ;
rdfs:comment "A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum." ;
rdfs:subClassOf obo:CHEBI_138000 .
obo:WBPhenotype_0001730 a rdfs:Class ;
rdfs:label "mating plug deficient" ;
rdfs:comment "Males do not form copulatory mating plug." ;
rdfs:subClassOf obo:WBPhenotype_0001728 .
obo:GO_1904690 a rdfs:Class ;
rdfs:label "positive regulation of cytoplasmic translational initiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation." ;
rdfs:subClassOf obo:GO_0045948 , obo:GO_0065007 , obo:GO_1904688 .
obo:GO_0032153 a rdfs:Class ;
rdfs:label "cell division site" ;
rdfs:comment "The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0009607 a rdfs:Class ;
rdfs:label "response to biotic stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." ;
rdfs:subClassOf obo:GO_0050896 .
obo:WBPhenotype_0000277 a rdfs:Class ;
rdfs:label "rhythm slow" ;
rdfs:comment "The timing of a biological cycle that recurs with regularity is delayed compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:CHEBI_26385 a rdfs:Class ;
rdfs:label "purine alkaloid" ;
rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_26401 .
obo:GO_0009966 a rdfs:Class ;
rdfs:label "regulation of signal transduction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of signal transduction." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0023051 , obo:GO_0048583 , obo:GO_0065007 .
obo:WBPhenotype_0000558 a rdfs:Class ;
rdfs:label "calcium channel modulator response variant" ;
rdfs:comment "Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 , obo:WBPhenotype_0001833 , obo:WBPhenotype_0002170 .
obo:CHEBI_26079 a rdfs:Class ;
rdfs:label "phosphoric acid derivative" ;
rdfs:subClassOf obo:CHEBI_36359 .
obo:PATO_0000499 a rdfs:Class ;
rdfs:label "decreased duration" ;
rdfs:comment "A duration quality of a process which is relatively low." ;
rdfs:subClassOf obo:PATO_0001309 , obo:PATO_0002302 .
obo:CHEBI_33892 a rdfs:Class ;
rdfs:label "iron coordination entity" ;
rdfs:subClassOf obo:CHEBI_24873 , obo:CHEBI_33861 .
obo:CHEBI_35315 a rdfs:Class ;
rdfs:label "deoxy hexoside" ;
rdfs:subClassOf obo:CHEBI_24400 .
obo:WBPhenotype_0000677 a rdfs:Class ;
rdfs:label "chemosensation defective" ;
rdfs:comment "Animals fail to receive, process or recognize a sensory chemical stimulus in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001050 .
obo:WBPhenotype_0001751 a rdfs:Class ;
rdfs:label "organism hypertonic lethality increased" ;
rdfs:comment "Animals exhibit increased lethality as a result of exposure to environments with a higher solute concentration than their own internal environment, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000141 , obo:WBPhenotype_0000876 .
obo:WBPhenotype_0000598 a rdfs:Class ;
rdfs:label "alimentary system morphology variant" ;
rdfs:comment "Variations in the form, structure or composition of the series of related tissues lying within the body cavity and devoted to feeding and digestion compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000534 .
obo:GO_0032102 a rdfs:Class ;
rdfs:label "negative regulation of response to external stimulus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." ;
rdfs:subClassOf obo:GO_0032101 , obo:GO_0048585 , obo:GO_0065007 .
obo:PATO_0001178 a rdfs:Class ;
rdfs:label "resistant to" ;
rdfs:comment "A resistance quality inhering in a bearer by virtue of the bearer's resistance to a stimulus." ;
rdfs:subClassOf obo:PATO_0001046 .
obo:GO_0006986 a rdfs:Class ;
rdfs:label "response to unfolded protein" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus." ;
rdfs:subClassOf obo:GO_0035966 .
obo:GO_0051653 a rdfs:Class ;
rdfs:label "spindle localization" ;
rdfs:comment "Any process in which is the spindle is transported to, and/or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0022402 , obo:GO_0051640 .
obo:GO_0043229 a rdfs:Class ;
rdfs:label "intracellular organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0043226 .
obo:GO_0043462 a rdfs:Class ;
rdfs:label "regulation of ATP-dependent activity" ;
rdfs:comment "Any process that modulates the rate of an ATP-dependent activity." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:WBPhenotype_0002429 a rdfs:Class ;
rdfs:label "protein glycosylation variant" ;
rdfs:comment "Animals exhibit variations in the degree to which some proteins are glycosylated, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001382 .
obo:WBPhenotype_0000513 a rdfs:Class ;
rdfs:label "obsolete touch response abnormal" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0001592 a rdfs:Class ;
rdfs:label "fainter" ;
rdfs:comment "Alternating periods of stopping and moving; Motion is interrupted by periods of inactivity lasting several seconds." ;
rdfs:subClassOf obo:WBPhenotype_0002308 .
obo:GO_0033045 a rdfs:Class ;
rdfs:label "regulation of sister chromatid segregation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of sister chromatid segregation." ;
rdfs:subClassOf obo:GO_0033044 , obo:GO_0051983 , obo:GO_0065007 .
obo:GO_0106049 a rdfs:Class ;
rdfs:label "regulation of cellular response to osmotic stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress." ;
rdfs:subClassOf obo:GO_0047484 , obo:GO_0065007 , obo:GO_0080135 .
obo:GO_0048519 a rdfs:Class ;
rdfs:label "negative regulation of biological process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:PATO_0000918 a rdfs:Class ;
rdfs:label "volume" ;
rdfs:comment "A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies." ;
rdfs:subClassOf obo:PATO_0001710 .
obo:WBPhenotype_0000056 a rdfs:Class ;
rdfs:label "late larval arrest" ;
rdfs:comment "Larvae arrest during late larval development. In C. elegans, larval arrest occurs during the L3 or L4 stages of larval development." ;
rdfs:subClassOf obo:WBPhenotype_0000059 .
obo:GO_0043296 a rdfs:Class ;
rdfs:label "apical junction complex" ;
rdfs:comment "A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability." ;
rdfs:subClassOf obo:GO_0005911 .
obo:GO_0060106 a rdfs:Class ;
rdfs:label "cortical layer of collagen and cuticulin-based cuticle extracellular matrix" ;
rdfs:comment "The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_33744 a rdfs:Class ;
rdfs:label "iron group molecular entity" ;
rdfs:subClassOf obo:CHEBI_33676 .
obo:CHEBI_50315 a rdfs:Class ;
rdfs:label "chloronium" ;
rdfs:subClassOf obo:CHEBI_50313 .
obo:WBPhenotype_0001407 a rdfs:Class ;
rdfs:label "protein expression reduced cell specific" ;
rdfs:comment "Variations that result in a decrease in protein expression in specific cells compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000120 .
obo:WBPhenotype_0002242 a rdfs:Class ;
rdfs:label "hypersensitive to iron deficiency" ;
rdfs:comment "Animals exhibit detrimental responses to iron deficiency more readily than control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002046 .
obo:GO_0031966 a rdfs:Class ;
rdfs:label "mitochondrial membrane" ;
rdfs:comment "Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031090 .
obo:CHEBI_28694 a rdfs:Class ;
rdfs:label "copper atom" ;
rdfs:subClassOf obo:CHEBI_33366 , obo:CHEBI_88184 .
obo:GO_0051781 a rdfs:Class ;
rdfs:label "positive regulation of cell division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell division." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0051302 , obo:GO_0065007 .
obo:CHEBI_26386 a rdfs:Class ;
rdfs:label "purine nucleobase" ;
rdfs:comment "A nucleobase whose skeleton is derived from purine." ;
rdfs:subClassOf obo:CHEBI_18282 , obo:CHEBI_26401 .
obo:WBPhenotype_0000026 a rdfs:Class ;
rdfs:label "lipid depleted" ;
rdfs:comment "Animals are unable to take up or store lipids. In C. elegans, this defect results in pale, skinny and arrested larva." ;
rdfs:subClassOf obo:WBPhenotype_0001183 .
obo:GO_0044085 a rdfs:Class ;
rdfs:label "cellular component biogenesis" ;
rdfs:comment "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." ;
rdfs:subClassOf obo:GO_0071840 .
obo:WBPhenotype_0001900 a rdfs:Class ;
rdfs:label "reduced levels of reduced glutathione" ;
rdfs:comment "Animals exhibit a decrease in the cellular levels of reduced glutathione (GSH), compared to control. Reduced levels of GSH may be an indication of susceptibility to oxidative stress." ;
rdfs:subClassOf obo:WBPhenotype_0001899 .
obo:GO_0050923 a rdfs:Class ;
rdfs:label "regulation of negative chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." ;
rdfs:subClassOf obo:GO_0050920 , obo:GO_0065007 .
obo:WBPhenotype_0002531 a rdfs:Class ;
rdfs:label "allophagy abnormal"@en ;
rdfs:comment "Animals exhibit variations in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded." ;
rdfs:subClassOf obo:WBPhenotype_0000736 .
obo:CHEBI_50803 a rdfs:Class ;
rdfs:label "nanoparticle" ;
rdfs:comment "A nanosized spherical or capsule-shaped structure." ;
rdfs:subClassOf obo:CHEBI_50795 .
obo:GO_0016071 a rdfs:Class ;
rdfs:label "mRNA metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." ;
rdfs:subClassOf obo:GO_0016070 .
obo:GO_1901031 a rdfs:Class ;
rdfs:label "regulation of response to reactive oxygen species" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of response to reactive oxygen species." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902882 .
obo:WBPhenotype_0001633 a rdfs:Class ;
rdfs:label "lethal gamete" ;
rdfs:comment "Animals produce ova/sperm that contain lethal factors as a result of chromosomal disjunction defects." ;
rdfs:subClassOf obo:WBPhenotype_0001174 .
obo:GO_0010972 a rdfs:Class ;
rdfs:label "negative regulation of G2/M transition of mitotic cell cycle" ;
rdfs:comment "Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0010389 , obo:GO_0065007 , obo:GO_1901991 , obo:GO_1902750 .
obo:WBPhenotype_0000743 a rdfs:Class ;
rdfs:label "RNAi response variant" ;
rdfs:comment "Animals exhibit variations in their response to gene silencing triggered by double stranded RNA (RNAi), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:CHEBI_30953 a rdfs:Class ;
rdfs:label "pyrazine" ;
rdfs:comment "A diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_38314 , obo:CHEBI_38627 .
obo:WBls_0000006 a rdfs:Class ;
rdfs:label "1-cell embryo Ce" ;
rdfs:comment "Also called zygote. -50min till 0min of first cleavage at 20 Centigrade. Contains 1 cell." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000813 , obo:WBls_0000823 .
obo:CHEBI_24757 a rdfs:Class ;
rdfs:label "hypochlorous acid" ;
rdfs:comment "A chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water." ;
rdfs:subClassOf obo:CHEBI_26523 , obo:CHEBI_33426 .
obo:WBPhenotype_0002661 a rdfs:Class ;
rdfs:label "constitutive expression of innate immune response genes"@en ;
rdfs:comment "Genes, whose expression is typically induced by an innate immune response, are actively expressed under conditions which would not normally induce an innate immune response gene expression program." ;
rdfs:subClassOf obo:WBPhenotype_0000135 .
obo:GO_0007620 a rdfs:Class ;
rdfs:label "copulation" ;
rdfs:comment "The act of sexual union between male and female, involving the transfer of sperm." ;
rdfs:subClassOf obo:GO_0007617 .
obo:CHEBI_47958 a rdfs:Class ;
rdfs:label "nicotinic acetylcholine receptor agonist" ;
rdfs:comment "An agonist that selectively binds to and activates a nicotinic acetylcholine receptor." ;
rdfs:subClassOf obo:CHEBI_38324 .
obo:GO_1903368 a rdfs:Class ;
rdfs:label "regulation of foraging behavior" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of foraging behavior." ;
rdfs:subClassOf obo:GO_0050795 , obo:GO_0065007 .
obo:GO_0060101 a rdfs:Class ;
rdfs:label "negative regulation of phagocytosis, engulfment" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ;
rdfs:subClassOf obo:GO_0050765 , obo:GO_0060099 , obo:GO_0065007 , obo:GO_1905154 .
obo:WBbt_0004421 a rdfs:Class ;
rdfs:label "Psub4" ;
rdfs:comment "Embryonic founder cell of germ line" ;
rdfs:subClassOf obo:WBbt_0008448 .
obo:GO_0043058 a rdfs:Class ;
rdfs:label "regulation of backward locomotion" ;
rdfs:comment "Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism." ;
rdfs:subClassOf obo:GO_0040012 , obo:GO_0065007 .
obo:GO_0009566 a rdfs:Class ;
rdfs:label "fertilization" ;
rdfs:comment "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ;
rdfs:subClassOf obo:GO_0022414 .
obo:PATO_0001476 a rdfs:Class ;
rdfs:label "decreased position" ;
rdfs:comment "A positional which is relatively low." ;
rdfs:subClassOf obo:PATO_0000140 , obo:PATO_0002303 .
obo:CHEBI_35470 a rdfs:Class ;
rdfs:label "central nervous system drug" ;
rdfs:comment "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:WBPhenotype_0001740 a rdfs:Class ;
rdfs:label "organ senescence variant" ;
rdfs:comment "Any variation in the preprogrammed process that occurs in an organism that is associated with the dismantling of an organ and an overall decline in metabolic function compared to control animals. This may include variations in the rate or extent of morphological disarray and of the breakdown or organelles, membranes and other cellular components." ;
rdfs:subClassOf obo:WBPhenotype_0000530 , obo:WBPhenotype_0000534 , obo:WBPhenotype_0000575 , obo:WBPhenotype_0001739 .
obo:WBPhenotype_0000738 a rdfs:Class ;
rdfs:label "organism environmental stimulus response variant" ;
rdfs:comment "The response to a change in the environment is altered compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:WBPhenotype_0000231 a rdfs:Class ;
rdfs:label "body size variant" ;
rdfs:comment "Animals exhibit variations in the physical dimensions of its body compared to control animals of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0000072 .
obo:CHEBI_30513 a rdfs:Class ;
rdfs:label "antimony atom" ;
rdfs:subClassOf obo:CHEBI_137980 , obo:CHEBI_33300 .
obo:CHEBI_149548 a rdfs:Class ;
rdfs:label "emetine(2+)" ;
rdfs:comment "An ammonium ion derivative obtained from protonation of the nitrogens of emetine. It is the major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35274 .
obo:WBPhenotype_0002418 a rdfs:Class ;
rdfs:label "spindle absent" ;
rdfs:comment "Cells lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ;
rdfs:subClassOf obo:WBPhenotype_0002414 .
obo:WBPhenotype_0000335 a rdfs:Class ;
rdfs:label "pharynx slippery" ;
rdfs:comment "Failure of pharyngeal contractions to trap and transport bacteria posteriorly. In C. elegans this defect results in a distention of the pharyngeal lumen." ;
rdfs:subClassOf obo:WBPhenotype_0000634 .
obo:GO_0006952 a rdfs:Class ;
rdfs:label "defense response" ;
rdfs:comment "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." ;
rdfs:subClassOf obo:GO_0006950 .
obo:GO_1904512 a rdfs:Class ;
rdfs:label "regulation of initiation of premeiotic DNA replication" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication." ;
rdfs:subClassOf obo:GO_0030174 , obo:GO_0033262 , obo:GO_0051445 , obo:GO_0065007 .
obo:GO_0051783 a rdfs:Class ;
rdfs:label "regulation of nuclear division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:CHEBI_29537 a rdfs:Class ;
rdfs:label "avermectin B1b" ;
rdfs:subClassOf obo:CHEBI_50344 .
obo:WBPhenotype_0002581 a rdfs:Class ;
rdfs:label "cell position variability increased"@en ;
rdfs:comment "One or more cells exhibit increases in the variability of cell position, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002580 .
obo:GO_0061651 a rdfs:Class ;
rdfs:label "Atg12 conjugating enzyme activity" ;
rdfs:comment "Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue." ;
rdfs:subClassOf obo:GO_0019777 , obo:GO_0061650 .
obo:GO_0170070 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial transcription" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription occurring in the mitochondrion." ;
rdfs:subClassOf obo:GO_0045892 , obo:GO_0065007 , obo:GO_1903108 .
obo:WBPhenotype_0002612 a rdfs:Class ;
rdfs:label "cytoplasmic streaming phenotype"@en ;
rdfs:comment "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is abnormal compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0002174 a rdfs:Class ;
rdfs:label "cell number decreased" ;
rdfs:comment "The number of cells in the organism is reduced compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002173 .
obo:WBPhenotype_0001567 a rdfs:Class ;
rdfs:label "nuclei enlarged" ;
rdfs:comment "Nuclei of specific cells are larger compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002607 .
obo:GO_0048520 a rdfs:Class ;
rdfs:label "positive regulation of behavior" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ;
rdfs:subClassOf obo:GO_0050795 , obo:GO_0051240 , obo:GO_0065007 .
obo:CHEBI_28616 a rdfs:Class ;
rdfs:label "carbamic acid" ;
rdfs:comment "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_35605 , obo:CHEBI_64708 .
obo:GO_0007285 a rdfs:Class ;
rdfs:label "primary spermatocyte growth" ;
rdfs:comment "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0048588 .
obo:CHEBI_26547 a rdfs:Class ;
rdfs:label "rhamnoside" ;
rdfs:subClassOf obo:CHEBI_35315 .
obo:CHEBI_2571 a rdfs:Class ;
rdfs:label "aliphatic alcohol" ;
rdfs:comment "An alcohol derived from an aliphatic compound." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:CHEBI_64248 a rdfs:Class ;
rdfs:label "tunicamycin B1" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a pentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:GO_0120031 a rdfs:Class ;
rdfs:label "plasma membrane bounded cell projection assembly" ;
rdfs:comment "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." ;
rdfs:subClassOf obo:GO_0030031 , obo:GO_0120036 .
obo:CHEBI_15837 a rdfs:Class ;
rdfs:label "isoamylol" ;
rdfs:comment "An primary alcohol that is butan-1-ol in which a hydrogen at position 3 has been replaced by a methyl group." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_134179 , obo:CHEBI_15734 , obo:CHEBI_50584 .
obo:CHEBI_75767 a rdfs:Class ;
rdfs:label "animal metabolite" ;
rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." ;
rdfs:subClassOf obo:CHEBI_75763 .
obo:GO_1905833 a rdfs:Class ;
rdfs:label "negative regulation of microtubule nucleation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation." ;
rdfs:subClassOf obo:GO_0010968 , obo:GO_0031115 , obo:GO_0065007 .
obo:WBPhenotype_0004022 a rdfs:Class ;
rdfs:label "amplitude of sinusoidal movement variant" ;
rdfs:comment "Any variation in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001703 .
obo:GO_0030335 a rdfs:Class ;
rdfs:label "positive regulation of cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 , obo:GO_2000147 .
obo:CHEBI_36359 a rdfs:Class ;
rdfs:label "phosphorus oxoacid derivative" ;
rdfs:subClassOf obo:CHEBI_33241 , obo:CHEBI_36360 .
obo:CHEBI_36709 a rdfs:Class ;
rdfs:label "aminoquinoline" ;
rdfs:comment "Any member of the class of quinolines in which the quinoline skeleton is substituted by one or more amino or substituted-amino groups." ;
rdfs:subClassOf obo:CHEBI_26513 , obo:CHEBI_33860 .
obo:WBPhenotype_0001021 a rdfs:Class ;
rdfs:label "male sexual development variant" ;
rdfs:comment "Genetically male animals exhibit deviations in the sexual program specific to males. In C. elegans, this often refers to XO animals being transformed into fertile hermaphrodites." ;
rdfs:subClassOf obo:WBPhenotype_0000822 .
obo:GO_0010467 a rdfs:Class ;
rdfs:label "gene expression" ;
rdfs:comment "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes." ;
rdfs:subClassOf obo:GO_0009059 .
obo:CHEBI_15705 a rdfs:Class ;
rdfs:label "L-alpha-amino acid" ;
rdfs:comment "Any α-amino acid having L-configuration at the α-carbon." ;
rdfs:subClassOf obo:CHEBI_33704 .
obo:WBPhenotype_0000401 a rdfs:Class ;
rdfs:label "no uterus" ;
rdfs:comment "Animals lack the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000624 , obo:WBPhenotype_0002556 .
obo:CHEBI_35506 a rdfs:Class ;
rdfs:label "alkaloid fundamental parent" ;
rdfs:subClassOf obo:CHEBI_35507 .
obo:CHEBI_36030 a rdfs:Class ;
rdfs:label "pentenoate" ;
rdfs:comment "A short-chain, saturated fatty acid anion that is the conjugate base of any pentenoic acid, formed by deprotonation of the carboxylic acid group." ;
rdfs:subClassOf obo:CHEBI_2580 , obo:CHEBI_58951 , obo:CHEBI_59203 .
obo:WBPhenotype_0000804 a rdfs:Class ;
rdfs:label "body development variant" ;
rdfs:comment "Variations in the progression of the overall structure or appearance of the animal over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000579 .
obo:WBPhenotype_0000378 a rdfs:Class ;
rdfs:label "pharyngeal pumping shallow" ;
rdfs:comment "Pharyngeal muscle contractions show less displacement than that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000634 .
obo:BFO_0000040 a rdfs:Class ;
rdfs:label "material entity"@en ;
rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
rdfs:subClassOf obo:BFO_0000004 .
obo:GO_0098764 a rdfs:Class ;
rdfs:label "meiosis I cell cycle phase" ;
rdfs:comment "A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs." ;
rdfs:subClassOf obo:GO_0098762 .
obo:RO_0002092 a rdf:Property ;
rdfs:label "happens during" ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002093 .
obo:CHEBI_32563 a rdfs:Class ;
rdfs:label "lysinate" ;
rdfs:comment "An α-amino-acid anion that is the conjugate base of lysine, arising from deprotonation of the carboxy group." ;
rdfs:subClassOf obo:CHEBI_33558 .
obo:GO_0031573 a rdfs:Class ;
rdfs:label "mitotic intra-S DNA damage checkpoint signaling" ;
rdfs:comment "A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression." ;
rdfs:subClassOf obo:GO_0044773 .
obo:GO_0016787 a rdfs:Class ;
rdfs:label "hydrolase activity" ;
rdfs:comment "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc." ;
rdfs:subClassOf obo:GO_0003824 .
obo:GO_0000377 a rdfs:Class ;
rdfs:label "RNA splicing, via transesterification reactions with bulged adenosine as nucleophile" ;
rdfs:comment "Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure." ;
rdfs:subClassOf obo:GO_0000375 .
obo:GO_1900101 a rdfs:Class ;
rdfs:label "regulation of endoplasmic reticulum unfolded protein response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902531 , obo:GO_1905897 .
obo:PATO_0001457 a rdfs:Class ;
rdfs:label "sensitivity of a process" ;
rdfs:comment "A quality of a process inhering in bearer by virtue of the bearer's disposition to respond to stimulation." ;
rdfs:subClassOf obo:PATO_0002062 .
obo:WBPhenotype_0002268 a rdfs:Class ;
rdfs:label "mitochondrial content decreased" ;
rdfs:comment "Animals exhibit decreases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining." ;
rdfs:subClassOf obo:WBPhenotype_0002266 .
obo:GO_0010977 a rdfs:Class ;
rdfs:label "negative regulation of neuron projection development" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ;
rdfs:subClassOf obo:GO_0010975 , obo:GO_0031345 , obo:GO_0065007 .
obo:CHEBI_33402 a rdfs:Class ;
rdfs:label "sulfur oxoacid" ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_33484 .
obo:CHEBI_50267 a rdfs:Class ;
rdfs:label "protective agent" ;
rdfs:comment "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0006413 a rdfs:Class ;
rdfs:label "translational initiation" ;
rdfs:comment "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0010506 a rdfs:Class ;
rdfs:label "regulation of autophagy" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0065007 .
obo:CHEBI_24532 a rdfs:Class ;
rdfs:label "organic heterocyclic compound" ;
rdfs:comment "A cyclic compound having as ring members atoms of carbon and at least of one other element." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_33832 , obo:CHEBI_5686 .
obo:GO_0007296 a rdfs:Class ;
rdfs:label "vitellogenesis" ;
rdfs:comment "The production of yolk. Yolk is a mixture of materials used for embryonic nutrition." ;
rdfs:subClassOf obo:GO_0007028 .
obo:WBPhenotype_0001165 a rdfs:Class ;
rdfs:label "excess maternal pronucleus early emb" ;
rdfs:comment "One-cell embryos have two or more maternal pronuclei." ;
rdfs:subClassOf obo:WBPhenotype_0001164 .
obo:GO_0071897 a rdfs:Class ;
rdfs:label "DNA biosynthetic process" ;
rdfs:comment "The biosynthetic process resulting in the formation of DNA." ;
rdfs:subClassOf obo:GO_0006259 , obo:GO_0141187 .
obo:WBPhenotype_0002576 a rdfs:Class ;
rdfs:label "gene expression level variation reduced"@en ;
rdfs:comment "Animals exhibit reduced amounts of variation in gene expression level between individual animals, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002574 .
obo:WBPhenotype_0000279 a rdfs:Class ;
rdfs:label "spicule insertion defective" ;
rdfs:comment "Males exhibit defects in the insertion of the male copulatory spicules into the mating partner. In C. elegan spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva." ;
rdfs:subClassOf obo:WBPhenotype_0001414 , obo:WBPhenotype_0004006 .
obo:GO_0048512 a rdfs:Class ;
rdfs:label "circadian behavior" ;
rdfs:comment "The specific behavior of an organism that recurs with a regularity of approximately 24 hours." ;
rdfs:subClassOf obo:GO_0007622 , obo:GO_0007623 .
obo:WBPhenotype_0001318 a rdfs:Class ;
rdfs:label "endogenous synaptic events variant" ;
rdfs:comment "Any variation in the currents observed in the absence of presynaptic action potentials and that are elicited by fusion of a single endogenous vesicle of transmitter compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002014 .
obo:WBPhenotype_0001440 a rdfs:Class ;
rdfs:label "cation positive chemotaxis defective" ;
rdfs:comment "Animals fail to move towards attractive cations." ;
rdfs:subClassOf obo:WBPhenotype_0001051 , obo:WBPhenotype_0001441 .
obo:GO_1901977 a rdfs:Class ;
rdfs:label "negative regulation of cell cycle checkpoint" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901976 , obo:GO_1901989 , obo:GO_1902532 .
obo:CHEBI_27081 a rdfs:Class ;
rdfs:label "transition element atom" ;
rdfs:comment "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell." ;
rdfs:subClassOf obo:CHEBI_33521 .
obo:WBPhenotype_0000693 a rdfs:Class ;
rdfs:label "male sperm fertilization defect" ;
rdfs:comment "Any perturbation that renders male derived sperm ineffective at fertilizing an oocyte." ;
rdfs:subClassOf obo:WBPhenotype_0000692 .
obo:WBPhenotype_0001662 a rdfs:Class ;
rdfs:label "spermatheca development variant" ;
rdfs:comment "Any variation in the progression of the somatic gonad structure that connects the distal gonad arm to the uterus over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000399 , obo:WBPhenotype_0000930 .
obo:PATO_0001433 a rdfs:Class ;
rdfs:label "growth quality of occurrent" ;
rdfs:comment "A quality of a single process which describes the growth of an organism, structure, or group of organisms." ;
rdfs:subClassOf obo:PATO_0001236 .
obo:GO_0031339 a rdfs:Class ;
rdfs:label "negative regulation of vesicle fusion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0031338 , obo:GO_0051051 , obo:GO_0065007 .
obo:GO_0008088 a rdfs:Class ;
rdfs:label "axo-dendritic transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules in neuron projections." ;
rdfs:subClassOf obo:GO_0010970 .
obo:WBPhenotype_0002578 a rdfs:Class ;
rdfs:label "basement membrane laminin level phenotype"@en ;
rdfs:comment "Animals exhibit variations in the amount of laminin in basement membranes, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002577 .
obo:WBPhenotype_0000253 a rdfs:Class ;
rdfs:label "movement erratic" ;
rdfs:comment "Animals exhibit a lack of consistency, regularity, or uniformity while traveling from one location to another." ;
rdfs:subClassOf obo:WBPhenotype_0001701 .
obo:GO_0006399 a rdfs:Class ;
rdfs:label "tRNA metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established." ;
rdfs:subClassOf obo:GO_0016070 .
obo:CHEBI_22527 a rdfs:Class ;
rdfs:label "aminopurine" ;
rdfs:comment "Any purine having at least one amino substituent." ;
rdfs:subClassOf obo:CHEBI_26401 .
obo:WBPhenotype_0000936 a rdfs:Class ;
rdfs:label "P4 lineage variant" ;
rdfs:comment "The descendants of the P4 blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000824 .
obo:WBPhenotype_0000095 a rdfs:Class ;
rdfs:label "M lineage variant" ;
rdfs:comment "The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals. In C. elegans the M lineage is a postembryonic mesodermal lineage." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000825 .
obo:WBbt_0005813 a rdfs:Class ;
rdfs:label "body wall musculature" ;
rdfs:comment "Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion." ;
rdfs:subClassOf obo:WBbt_0005737 .
obo:WBPhenotype_0000988 a rdfs:Class ;
rdfs:label "gland cell physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the gland cell to carry out its normal functions or activities or be able to perceive and respond to signals, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0000209 a rdfs:Class ;
rdfs:label "short defecation cycle" ;
rdfs:comment "The mean time between the onset of the defecation motor program is shorter than that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000207 .
obo:WBPhenotype_0002122 a rdfs:Class ;
rdfs:label "persistence of paternal mitochondria" ;
rdfs:comment "Mitochondria from spermatazoa persist in the developing embryo and animal as a result of bypassing the degradation mechanism that normally destroys paternal mitochondria immediately after fertilization. This can often lead to a form of heteroplasmy." ;
rdfs:subClassOf obo:WBPhenotype_0002121 .
obo:GO_0016874 a rdfs:Class ;
rdfs:label "ligase activity" ;
rdfs:comment "Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient." ;
rdfs:subClassOf obo:GO_0003824 .
obo:CHEBI_29075 a rdfs:Class ;
rdfs:label "mononucleotide" ;
rdfs:subClassOf obo:CHEBI_36976 .
obo:GO_0048585 a rdfs:Class ;
rdfs:label "negative regulation of response to stimulus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0048583 , obo:GO_0065007 .
obo:CHEBI_26834 a rdfs:Class ;
rdfs:label "sulfur-containing amino acid" ;
rdfs:subClassOf obo:CHEBI_33576 , obo:CHEBI_33709 .
obo:WBPhenotype_0000506 a rdfs:Class ;
rdfs:label "bursa swollen" ;
rdfs:comment "The adult male tail, including the lateral fan and rays, appears bloated or distended." ;
rdfs:subClassOf obo:WBPhenotype_0000342 .
obo:WBPhenotype_0000372 a rdfs:Class ;
rdfs:label "no polar body formation" ;
rdfs:comment "Animals lack the two small cells produced, each during one of the two meiotic cell divisions (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000775 , obo:WBPhenotype_0002552 .
obo:WBPhenotype_0002245 a rdfs:Class ;
rdfs:label "endogenous zinc levels reduced" ;
rdfs:comment "Animals exhibit reduced levels of endogenous zinc compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001849 .
obo:WBPhenotype_0001053 a rdfs:Class ;
rdfs:label "cyclic nucleotide positive chemotaxis variant" ;
rdfs:comment "Animals exhibit variations in the characteristic movement towards cyclic nucleotides compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001047 .
obo:CHEBI_26650 a rdfs:Class ;
rdfs:label "serine family amino acid" ;
rdfs:comment "An α-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class." ;
rdfs:subClassOf obo:CHEBI_33704 .
obo:GO_0050804 a rdfs:Class ;
rdfs:label "modulation of chemical synaptic transmission" ;
rdfs:comment "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0099177 .
obo:GO_0030010 a rdfs:Class ;
rdfs:label "establishment of cell polarity" ;
rdfs:comment "The specification and formation of anisotropic intracellular organization or cell growth patterns." ;
rdfs:subClassOf obo:GO_0007163 .
obo:WBPhenotype_0001926 a rdfs:Class ;
rdfs:label "gonad sheath contraction rate increased" ;
rdfs:comment "Basal contraction rate and or peak contraction rate of the gonadal sheath is increased relative to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001199 .
obo:WBPhenotype_0000929 a rdfs:Class ;
rdfs:label "hermaphrodite physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required to carry out hermaphrodite-specific activities or to be able to perceive and respond to hermaphrodite-specific stimuli compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000889 .
obo:GO_0060538 a rdfs:Class ;
rdfs:label "skeletal muscle organ development" ;
rdfs:comment "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." ;
rdfs:subClassOf obo:GO_0007517 .
obo:WBPhenotype_0000024 a rdfs:Class ;
rdfs:label "serotonin resistant" ;
rdfs:comment "Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 .
obo:GO_0032230 a rdfs:Class ;
rdfs:label "positive regulation of synaptic transmission, GABAergic" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ;
rdfs:subClassOf obo:GO_0032228 , obo:GO_0050806 , obo:GO_0065007 .
obo:CHEBI_57887 a rdfs:Class ;
rdfs:label "tryptaminium" ;
rdfs:comment "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_65296 .
obo:WBPhenotype_0002657 a rdfs:Class ;
rdfs:label "dietary saturated fatty acid intolerant"@en ;
rdfs:comment "Animals exhibit intolerance (e.g. lethality or significant growth defect) when exposed to saturated fatty acids via the diet, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001072 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000604 a rdfs:Class ;
rdfs:label "nervous system morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000534 .
obo:WBPhenotype_0001796 a rdfs:Class ;
rdfs:label "organism hypersensitive interstrand cross link agents" ;
rdfs:comment "Animals exhibit increased sensitivity to interstrand cross-linking agents, such as HN2 (nitrogen mustard) and CDDP (cisplatin) compared to control. In C. elegans, increased sensitivity to these agents is often observed as a decrease in survival compared to control animals after exposure to the agent." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBPhenotype_0002114 a rdfs:Class ;
rdfs:label "swimming induced paralysis" ;
rdfs:comment "Animals become paralyzed after a measured amount of time swimming. In C. elegans, more then 80 percent of wild-type animals continue swimming vigorously in liquid even after 30 minutes." ;
rdfs:subClassOf obo:WBPhenotype_0001700 .
obo:WBPhenotype_0002309 a rdfs:Class ;
rdfs:label "pausing decreased" ;
rdfs:comment "Animals exhibit a decrease in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002308 .
obo:WBPhenotype_0001597 a rdfs:Class ;
rdfs:label "muscle missing" ;
rdfs:comment "Any variation that results in a fewer than control number of muscle cells." ;
rdfs:subClassOf obo:WBPhenotype_0000622 , obo:WBPhenotype_0002174 , obo:WBPhenotype_0002552 .
obo:WBbt_0005175 a rdfs:Class ;
rdfs:label "gonad" ;
rdfs:comment "organ producing either sperm or ova." ;
rdfs:subClassOf obo:WBbt_0003760 .
obo:GO_1905628 a rdfs:Class ;
rdfs:label "negative regulation of serotonin biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0065007 , obo:GO_1905627 .
obo:WBPhenotype_0002136 a rdfs:Class ;
rdfs:label "no anchor cell" ;
rdfs:comment "Animals are missing the anchor cell. In C. elegans the anchor cell is a key organizer of vulval patterning and morphogenesis." ;
rdfs:subClassOf obo:WBPhenotype_0000399 , obo:WBPhenotype_0002174 , obo:WBPhenotype_0002552 .
obo:PATO_0000033 a rdfs:Class ;
rdfs:label "concentration of" ;
rdfs:comment "A quality inhering in a substance by virtue of the amount of the bearer's there is mixed with another substance." ;
rdfs:subClassOf obo:PATO_0000070 .
obo:GO_0034504 a rdfs:Class ;
rdfs:label "protein localization to nucleus" ;
rdfs:comment "A process in which a protein transports or maintains the localization of another protein to the nucleus." ;
rdfs:subClassOf obo:GO_0033365 .
obo:CHEBI_25698 a rdfs:Class ;
rdfs:label "ether" ;
rdfs:comment "An organooxygen compound with formula ROR, where R is not hydrogen." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:WBPhenotype_0002274 a rdfs:Class ;
rdfs:label "plugged on body" ;
rdfs:comment "Males receive copulatory plugs from other males, deposited elsewhere on their bodies, in the absence of any orifice. This typically involves penetration of the depositing male's spicules directly through the cuticle of the recipient male." ;
rdfs:subClassOf obo:WBPhenotype_0001728 .
obo:WBPhenotype_0001013 a rdfs:Class ;
rdfs:label "pathogen susceptibility increased" ;
rdfs:comment "Animals are more prone to infection compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001012 .
obo:WBPhenotype_0001238 a rdfs:Class ;
rdfs:label "male mating latency variant" ;
rdfs:comment "Any variation in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva." ;
rdfs:subClassOf obo:WBPhenotype_0000648 , obo:WBPhenotype_0002551 .
obo:WBPhenotype_0002162 a rdfs:Class ;
rdfs:label "multipolar mitotic spindle" ;
rdfs:comment "Cells exhibit mitotic spindles with more than two poles." ;
rdfs:subClassOf obo:WBPhenotype_0001215 , obo:WBPhenotype_0001743 .
obo:PATO_0000761 a rdfs:Class ;
rdfs:label "decreased behavioural activity" ;
rdfs:comment "A behavioral quality of a process inhering in a bearer by virtue of the bearer's exhibiting reduced activity." ;
rdfs:subClassOf obo:PATO_0001707 , obo:PATO_0002303 .
obo:WBPhenotype_0001548 a rdfs:Class ;
rdfs:label "dauer axial ratio variant" ;
rdfs:comment "Any variation in the ratio of the body length to body width in a dauer stage animal, compared to control. Long thin animals will have a high axial ratio." ;
rdfs:subClassOf obo:WBPhenotype_0001545 .
obo:GO_0065009 a rdfs:Class ;
rdfs:label "regulation of molecular function" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ;
rdfs:subClassOf obo:GO_0065007 .
obo:GO_1905940 a rdfs:Class ;
rdfs:label "negative regulation of gonad development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1905939 , obo:GO_2000242 .
obo:GO_0045807 a rdfs:Class ;
rdfs:label "positive regulation of endocytosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endocytosis." ;
rdfs:subClassOf obo:GO_0030100 , obo:GO_0051050 , obo:GO_0051130 , obo:GO_0065007 .
obo:CHEBI_50511 a rdfs:Class ;
rdfs:label "bipyridines" ;
rdfs:comment "Compounds containing a bipyridine group." ;
rdfs:subClassOf obo:CHEBI_36820 , obo:CHEBI_38101 , obo:CHEBI_64459 .
obo:WBPhenotype_0001969 a rdfs:Class ;
rdfs:label "germ cell compartment morphology variant" ;
rdfs:comment "Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis). These compartments eventually undergo cellularization and become oocytes." ;
rdfs:subClassOf obo:WBPhenotype_0000900 .
obo:CHEBI_78295 a rdfs:Class ;
rdfs:label "food component" ;
rdfs:comment "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." ;
rdfs:subClassOf obo:CHEBI_52211 .
obo:PATO_0000947 a rdfs:Class ;
rdfs:label "elliptic" ;
rdfs:comment "A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section." ;
rdfs:subClassOf obo:PATO_0002318 .
obo:WBPhenotype_0000898 a rdfs:Class ;
rdfs:label "blast cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of blast cells compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002108 .
obo:CHEBI_64257 a rdfs:Class ;
rdfs:label "tunicamycin C2" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a hexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:CHEBI_60240 a rdfs:Class ;
rdfs:label "divalent metal cation" ;
rdfs:comment "A metal cation with a valence of two." ;
rdfs:subClassOf obo:CHEBI_25213 , obo:CHEBI_64641 .
obo:GO_1904291 a rdfs:Class ;
rdfs:label "positive regulation of mitotic DNA damage checkpoint" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090068 , obo:GO_1904289 , obo:GO_2000003 .
obo:CHEBI_33707 a rdfs:Class ;
rdfs:label "gamma-amino acid" ;
rdfs:comment "A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position γ to the carboxy group." ;
rdfs:subClassOf obo:CHEBI_83820 .
obo:WBbt_0008074 a rdfs:Class ;
rdfs:label "syncytium" ;
rdfs:comment "cell that has more than one nucleus." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:CHEBI_9727 a rdfs:Class ;
rdfs:label "trimethadione" ;
rdfs:comment "An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_55374 .
obo:WBPhenotype_0000644 a rdfs:Class ;
rdfs:label "paralyzed" ;
rdfs:comment "Animals do not move and are not responsive to external mechanical stimulation." ;
rdfs:subClassOf obo:WBPhenotype_0001213 .
obo:WBPhenotype_0002617 a rdfs:Class ;
rdfs:label "cytosolic calcium levels increased"@en ;
rdfs:comment "Cells exhibit a higher level of calcium in the cytosol, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002616 .
obo:CHEBI_33566 a rdfs:Class ;
rdfs:label "catechols" ;
rdfs:comment "Any compound containing an o-diphenol component." ;
rdfs:subClassOf obo:CHEBI_33570 .
obo:WBPhenotype_0001638 a rdfs:Class ;
rdfs:label "obsolete endosome fusion defective" ;
rdfs:comment "OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes." .
obo:WBPhenotype_0000456 a rdfs:Class ;
rdfs:label "touch resistant" ;
rdfs:comment "Variations in characteristic response with respect to perception or transmission of a touch stimulus compared to responses in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:GO_0000768 a rdfs:Class ;
rdfs:label "syncytium formation by cell-cell fusion" ;
rdfs:comment "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ;
rdfs:subClassOf obo:GO_0140253 .
obo:GO_0032055 a rdfs:Class ;
rdfs:label "negative regulation of translation in response to stress" ;
rdfs:comment "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0017148 , obo:GO_0043555 , obo:GO_0065007 .
obo:WBPhenotype_0000575 a rdfs:Class ;
rdfs:label "organ system physiology phenotype" ;
rdfs:comment "Animals exhibit variations in a physical or chemical process required for organs or tissues to carry out their normal functions or for their ability to perceive and respond to stimuli compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000519 .
obo:CHEBI_48355 a rdfs:Class ;
rdfs:label "non-polar solvent" ;
rdfs:subClassOf obo:CHEBI_46787 .
obo:WBPhenotype_0001071 a rdfs:Class ;
rdfs:label "active phase switch defective" ;
rdfs:comment "Activation of the active phase of egg laying is defective, leading to an abnormally long inactive phase, based on the analysis of the distribution of the log intervals of egg-laying events." ;
rdfs:subClassOf obo:WBPhenotype_0001064 .
obo:GO_2000623 a rdfs:Class ;
rdfs:label "negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902373 , obo:GO_2000622 .
obo:GO_0032092 a rdfs:Class ;
rdfs:label "positive regulation of protein binding" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein binding." ;
rdfs:subClassOf obo:GO_0043393 , obo:GO_0051099 , obo:GO_0065007 .
obo:GO_0141060 a rdfs:Class ;
rdfs:label "disruption of anatomical structure in another organism" ;
rdfs:comment "The disruption of an anatomical structure of another organism, leading to damage or temporary subversion of that structure." ;
rdfs:subClassOf obo:GO_0044419 .
obo:GO_0005777 a rdfs:Class ;
rdfs:label "peroxisome" ;
rdfs:comment "A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism." ;
rdfs:subClassOf obo:GO_0042579 .
obo:WBbt_0005465 a rdfs:Class ;
rdfs:label "posterior lateral ganglion" ;
rdfs:comment "ganglion on the lateral side, in postior portion of the body, associated with posterior deirid." ;
rdfs:subClassOf obo:WBbt_0005332 .
obo:WBPhenotype_0000914 a rdfs:Class ;
rdfs:label "excretory gland cell morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000601 , obo:WBPhenotype_0000901 .
obo:GO_1905516 a rdfs:Class ;
rdfs:label "positive regulation of fertilization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of fertilization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080154 , obo:GO_2000243 .
obo:WBPhenotype_0000525 a rdfs:Class ;
rdfs:label "organism behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of an organism in response to external or internal stimuli compared to that observed in control organisms." ;
rdfs:subClassOf obo:WBPhenotype_0000517 .
obo:WBPhenotype_0000850 a rdfs:Class ;
rdfs:label "touch resistant anterior body" ;
rdfs:comment "Animal does not respond to stroking in the anterior body region with a hair or similar fiber compared to control. In C. elegans, the anterior region is defined as the body region that lies between the posterior bulb of the pharynx and the vulva." ;
rdfs:subClassOf obo:WBPhenotype_0000456 .
obo:WBPhenotype_0002597 a rdfs:Class ;
rdfs:label "gustatory learning abnormal"@en ;
rdfs:comment "Variations in the behavioral plasticity induced by the integration of two sensory signals (one of which is gustation (taste)) compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype have an abnormal response to the trained stimuli compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001780 .
obo:WBbt_0005425 a rdfs:Class ;
rdfs:label "phasmid sensillum" ;
rdfs:comment "bilateral sensory organ in the tail, similar to the amphid in the head." ;
rdfs:subClassOf obo:WBbt_0006929 .
obo:GO_0051311 a rdfs:Class ;
rdfs:label "meiotic metaphase chromosome alignment" ;
rdfs:comment "A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division." ;
rdfs:subClassOf obo:GO_0051310 , obo:GO_1903046 .
obo:CL_0000365 a rdfs:Class ;
rdfs:label "animal zygote" ;
rdfs:comment "Diploid cell produced by the fusion of sperm cell nucleus and egg cell." ;
rdfs:subClassOf obo:CL_0000007 , obo:CL_0000255 , obo:CL_0010017 .
obo:WBPhenotype_0001485 a rdfs:Class ;
rdfs:label "ER stress response variant" ;
rdfs:comment "Animals exhibit variations in their response to the presence of unfolded proteins in the endoplasmic reticulum (ER) or to other ER-related stressors compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000142 .
obo:WBPhenotype_0001313 a rdfs:Class ;
rdfs:label "uterine muscle variant" ;
rdfs:comment "Any variation in the progression of the sex-specific muscles of the hermaphrodite, over time, whose contractions squeeze on the uterus to help move eggs towards the vulval opening compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000282 , obo:WBPhenotype_0002551 .
obo:WBPhenotype_0001164 a rdfs:Class ;
rdfs:label "excess pronucleus early emb" ;
rdfs:comment "There is either more than one maternal or paternal pronucleus in the inviable embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001162 , obo:WBPhenotype_0002175 .
obo:WBPhenotype_0001500 a rdfs:Class ;
rdfs:label "pentanedione chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanedione." ;
rdfs:subClassOf obo:WBPhenotype_0001467 .
obo:PATO_0001551 a rdfs:Class ;
rdfs:label "increased sensitivity of a process" ;
rdfs:comment "A sensitivity of a process which is higher than normal or average." ;
rdfs:subClassOf obo:PATO_0001457 , obo:PATO_0002304 .
obo:WBPhenotype_0001366 a rdfs:Class ;
rdfs:label "male fan development variant" ;
rdfs:comment "Any variation in the process whose specific outcome is the progression of the male fan over time, from its formation to the mature structure, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001365 .
obo:CHEBI_35406 a rdfs:Class ;
rdfs:label "oxoanion" ;
rdfs:comment "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." ;
rdfs:subClassOf obo:CHEBI_25741 , obo:CHEBI_33273 .
obo:WBPhenotype_0002125 a rdfs:Class ;
rdfs:label "growth inhibition response to chemical" ;
rdfs:comment "Animals do not grow fast or the quality of growth is decreased when exposed to a specific chemical compound when compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:CHEBI_33443 a rdfs:Class ;
rdfs:label "halogen oxoanion" ;
rdfs:subClassOf obo:CHEBI_24471 , obo:CHEBI_24834 , obo:CHEBI_35406 .
obo:WBPhenotype_0002256 a rdfs:Class ;
rdfs:label "selenium response variant" ;
rdfs:comment "Animals exhibit variations in their response to selenium compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 , obo:WBPhenotype_0000591 .
obo:GO_0045168 a rdfs:Class ;
rdfs:label "cell-cell signaling involved in cell fate commitment" ;
rdfs:comment "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." ;
rdfs:subClassOf obo:GO_0007267 .
obo:WBPhenotype_0000714 a rdfs:Class ;
rdfs:label "obsolete disorganized muscle" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0001283 a rdfs:Class ;
rdfs:label "organelle metabolism variant" ;
rdfs:comment "Variations in the chemical reactions and pathways of an organelle compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000585 .
obo:WBPhenotype_0001249 a rdfs:Class ;
rdfs:label "amphid channel cilia morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or composition of the dendritic projections of the amphid sensory neurons that traverse the sensillum pore to connect with the outside of the animal, compared to that observed in control animals. In C. elegans, amphid channel cilia morphology is frequently assayed by dye-filling experiments using FITC, DiI or DiO." ;
rdfs:subClassOf obo:WBPhenotype_0000615 .
obo:CHEBI_47017 a rdfs:Class ;
rdfs:label "tetrahydrofuranol" ;
rdfs:subClassOf obo:CHEBI_26912 .
obo:GO_0000235 a rdfs:Class ;
rdfs:label "astral microtubule" ;
rdfs:comment "Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." ;
rdfs:subClassOf obo:GO_0005876 , obo:GO_0005881 .
obo:CHEBI_33674 a rdfs:Class ;
rdfs:label "s-block molecular entity" ;
rdfs:comment "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." ;
rdfs:subClassOf obo:CHEBI_33579 .
obo:WBPhenotype_0001768 a rdfs:Class ;
rdfs:label "commissure number variant" ;
rdfs:comment "Variations in the quantity of circumferential axonal tracts from the number observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001226 .
obo:CHEBI_26513 a rdfs:Class ;
rdfs:label "quinolines" ;
rdfs:comment "A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_38101 .
obo:GO_0008152 a rdfs:Class ;
rdfs:label "metabolic process" ;
rdfs:comment "A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0001649 a rdfs:Class ;
rdfs:label "Fluorouracil resistant" ;
rdfs:comment "Animals fail to respond to the concentration of Fluorouracil (5-FU) that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. Elegans Fluorouracil induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 .
obo:WBPhenotype_0001586 a rdfs:Class ;
rdfs:label "multiple anchor cells" ;
rdfs:comment "Animals contain more than one anchor cell. In C. elegans, presumptive ventral uterine cells undergo fate transformation and instead acquire the properties of an anchor cell (often due to defects in lateral signaling)." ;
rdfs:subClassOf obo:WBPhenotype_0002175 .
obo:GO_0051048 a rdfs:Class ;
rdfs:label "negative regulation of secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ;
rdfs:subClassOf obo:GO_0051046 , obo:GO_0051051 , obo:GO_0065007 .
obo:WBPhenotype_0001601 a rdfs:Class ;
rdfs:label "biogenic amine receptor antagonist resistant" ;
rdfs:comment "Animals fail to respond to the concentration of biogenic amine receptor antagonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 .
obo:WBPhenotype_0002480 a rdfs:Class ;
rdfs:label "heme levels variant" ;
rdfs:comment "Animals exhibit variations in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:CHEBI_26082 a rdfs:Class ;
rdfs:label "phosphorus molecular entity" ;
rdfs:subClassOf obo:CHEBI_33302 .
obo:WBPhenotype_0000592 a rdfs:Class ;
rdfs:label "copper response variant" ;
rdfs:comment "Animals exhibit variations in their response to copper compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000591 .
obo:WBPhenotype_0001442 a rdfs:Class ;
rdfs:label "sodium acetate chemotaxis defective" ;
rdfs:comment "Failure in directed movement in response to sodium acetate. In C. elegans, sodium acetate is an attractant. Sodium acetate has also subsequently been used to assay for Na+ attraction in C. elegans." ;
rdfs:subClassOf obo:WBPhenotype_0001441 , obo:WBPhenotype_0001461 .
obo:GO_0048666 a rdfs:Class ;
rdfs:label "neuron development" ;
rdfs:comment "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0048468 .
obo:WBPhenotype_0001933 a rdfs:Class ;
rdfs:label "synaptic vesicle tag abnormal in mechanosensory neurons" ;
rdfs:comment "The pattern of localization of presynaptic markers is disrupted compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000847 .
obo:CHEBI_25608 a rdfs:Class ;
rdfs:label "nucleoside phosphate" ;
rdfs:comment "A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates." ;
rdfs:subClassOf obo:CHEBI_25703 , obo:CHEBI_37734 , obo:CHEBI_61120 .
obo:GO_0032205 a rdfs:Class ;
rdfs:label "negative regulation of telomere maintenance" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." ;
rdfs:subClassOf obo:GO_0032204 , obo:GO_0051053 , obo:GO_0065007 , obo:GO_2001251 .
obo:CL_0002371 a rdfs:Class ;
rdfs:label "obsolete somatic cell" ;
rdfs:comment "OBSOLETE. A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell)." .
obo:WBPhenotype_0001550 a rdfs:Class ;
rdfs:label "dauer buccal cavity morphology variant" ;
rdfs:comment "Variations in the form or composition of the cuticle-lined lumenal region which lies just behind the lips at the entrance to the pharyngeal lumen in dauer stage animals compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001545 , obo:WBPhenotype_0002558 .
obo:CHEBI_48278 a rdfs:Class ;
rdfs:label "serotonergic drug" ;
rdfs:subClassOf obo:CHEBI_35942 .
obo:WBPhenotype_0002608 a rdfs:Class ;
rdfs:label "humpback"@en ;
rdfs:comment "A body elongation defect in which embryos develop abnormally bulged dorsal surfaces." ;
rdfs:subClassOf obo:WBPhenotype_0000242 , obo:WBPhenotype_0001136 .
obo:WBPhenotype_0001008 a rdfs:Class ;
rdfs:label "male nervous system development variant" ;
rdfs:comment "Variations in the progression of a set of interacting or interdependent entities forming the male nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses." ;
rdfs:subClassOf obo:WBPhenotype_0000623 .
obo:WBPhenotype_0000125 a rdfs:Class ;
rdfs:label "enzyme activity increased" ;
rdfs:comment "Any variation that results in an increase in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ;
rdfs:subClassOf obo:WBPhenotype_0000727 .
obo:WBPhenotype_0002346 a rdfs:Class ;
rdfs:label "forward locomotion increased" ;
rdfs:comment "Animals spend more time in forward locomotion, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002345 .
obo:WBPhenotype_0001452 a rdfs:Class ;
rdfs:label "octanol chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of octanol. In C. elegans, octanol is typically a repellant." ;
rdfs:subClassOf obo:WBPhenotype_0001455 .
obo:WBPhenotype_0000219 a rdfs:Class ;
rdfs:label "vulval cell induction reduced" ;
rdfs:comment "Vulval precursor cells receive a decrease in inductive signal leading to fewer VPCs adopting vulval fates compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001272 .
obo:GO_0051985 a rdfs:Class ;
rdfs:label "negative regulation of chromosome segregation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0051983 , obo:GO_0065007 .
obo:WBPhenotype_0000536 a rdfs:Class ;
rdfs:label "cell physiology phenotype" ;
rdfs:comment "Animals exhibit variations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal functions or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000519 .
obo:WBPhenotype_0001785 a rdfs:Class ;
rdfs:label "associative memory defective" ;
rdfs:comment "Animals are deficient in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms." ;
rdfs:subClassOf obo:WBPhenotype_0002564 .
obo:WBPhenotype_0001068 a rdfs:Class ;
rdfs:label "egg laying serotonin resistant" ;
rdfs:comment "Animals are not induced to lay eggs in reponse to exogenous serotonin. Serotonin stimulates egg-laying in C. elegans." ;
rdfs:subClassOf obo:WBPhenotype_0000024 , obo:WBPhenotype_0001629 .
obo:WBPhenotype_0000552 a rdfs:Class ;
rdfs:label "GABA levels variant" ;
rdfs:comment "Animals exhibit variations in the amount of GABA compared to control animals at a defined stage." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0002410 a rdfs:Class ;
rdfs:label "cleavage furrow defective" ;
rdfs:comment "Cells exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ;
rdfs:subClassOf obo:WBPhenotype_0002408 .
obo:WBPhenotype_0000586 a rdfs:Class ;
rdfs:label "bleach hypersensitive" ;
rdfs:comment "Animals respond to bleach at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000524 , obo:WBPhenotype_0001918 .
obo:GO_0045740 a rdfs:Class ;
rdfs:label "positive regulation of DNA replication" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of DNA replication." ;
rdfs:subClassOf obo:GO_0006275 , obo:GO_0051054 , obo:GO_0065007 .
obo:WBPhenotype_0000703 a rdfs:Class ;
rdfs:label "epithelial morphology variant" ;
rdfs:comment "Variations in the form, composition or structure of the layer of cells that cover the external surface of an organism and form the inner lining between the tissues and organs of that organism and the external environment compared to control. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000600 .
obo:WBPhenotype_0002010 a rdfs:Class ;
rdfs:label "protein turnover variant" ;
rdfs:comment "The dynamics of the replacement of old proteins by newly synthesized or modified proteins varies from that of control animals. This phenotype is often measured by fluorescence recovery after photobleaching (FRAP)." ;
rdfs:subClassOf obo:WBPhenotype_0001644 .
obo:CHEBI_46787 a rdfs:Class ;
rdfs:label "solvent" ;
rdfs:comment "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." ;
rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_51086 .
obo:GO_1905146 a rdfs:Class ;
rdfs:label "lysosomal protein catabolic process" ;
rdfs:comment "Any cellular protein catabolic process that takes place in a lysosome." ;
rdfs:subClassOf obo:GO_0007039 , obo:GO_0030163 .
obo:WBPhenotype_0002567 a rdfs:Class ;
rdfs:label "long-term associative olfactory memory defective"@en ;
rdfs:comment "Animals are deficient in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s)." ;
rdfs:subClassOf obo:WBPhenotype_0001785 , obo:WBPhenotype_0002566 .
obo:CHEBI_74213 a rdfs:Class ;
rdfs:label "EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor" ;
rdfs:comment "An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1)." ;
rdfs:subClassOf obo:CHEBI_76848 .
obo:GO_0046824 a rdfs:Class ;
rdfs:label "positive regulation of nucleocytoplasmic transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0046822 , obo:GO_0065007 .
obo:CHEBI_233500 a rdfs:Class ;
rdfs:label "post-transition metal atom" ;
rdfs:comment "A group of metal atoms that are located in the periodic table between transition metals and metalloids." ;
rdfs:subClassOf obo:CHEBI_33521 .
obo:GO_0048332 a rdfs:Class ;
rdfs:label "mesoderm morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the mesoderm are generated and organized." ;
rdfs:subClassOf obo:GO_0048729 .
obo:GO_0043050 a rdfs:Class ;
rdfs:label "nematode pharyngeal pumping" ;
rdfs:comment "The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes." ;
rdfs:subClassOf obo:GO_0042755 .
obo:CHEBI_25414 a rdfs:Class ;
rdfs:label "monoatomic monocation" ;
rdfs:subClassOf obo:CHEBI_23906 .
obo:GO_0090139 a rdfs:Class ;
rdfs:label "mitochondrial chromosome packaging" ;
rdfs:comment "A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure." ;
rdfs:subClassOf obo:GO_0051276 .
obo:WBPhenotype_0001716 a rdfs:Class ;
rdfs:label "forward point velocity variant" ;
rdfs:comment "Animals exhibit variations in the velocity of forward translocation of any point along the animal's track from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0004025 .
obo:GO_0016192 a rdfs:Class ;
rdfs:label "vesicle-mediated transport" ;
rdfs:comment "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 .
obo:GO_0007143 a rdfs:Class ;
rdfs:label "female meiotic nuclear division" ;
rdfs:comment "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." ;
rdfs:subClassOf obo:GO_0000280 , obo:GO_0140013 .
obo:CHEBI_79388 a rdfs:Class ;
rdfs:label "divalent inorganic anion" ;
rdfs:comment "Any inorganic anion with a valency of two." ;
rdfs:subClassOf obo:CHEBI_24834 .
obo:WBPhenotype_0002425 a rdfs:Class ;
rdfs:label "protein aggregation induced behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions in response to external or internal stimuli in response to the aggregation of proteins." ;
rdfs:subClassOf obo:WBPhenotype_0001405 .
obo:CHEBI_33521 a rdfs:Class ;
rdfs:label "metal atom" ;
rdfs:comment "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:WBbt_0006794 a rdfs:Class ;
rdfs:label "male gonad" ;
rdfs:comment "gonad of a male animal, produces sperm." ;
rdfs:subClassOf obo:WBbt_0005175 .
obo:GO_0090592 a rdfs:Class ;
rdfs:label "DNA synthesis involved in DNA replication" ;
rdfs:comment "Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA." ;
rdfs:subClassOf obo:GO_0071897 .
obo:GO_2001141 a rdfs:Class ;
rdfs:label "regulation of RNA biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010556 , obo:GO_0051252 , obo:GO_0065007 .
obo:CHEBI_15355 a rdfs:Class ;
rdfs:label "acetylcholine" ;
rdfs:comment "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35287 , obo:CHEBI_47622 .
obo:CHEBI_24432 a rdfs:Class ;
rdfs:label "biological role" ;
rdfs:comment "A role played by the molecular entity or part thereof within a biological context." ;
rdfs:subClassOf obo:CHEBI_50906 .
obo:WBls_0000812 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during proliferating embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the proliferating embryo life stage" ;
rdfs:subClassOf obo:WBls_0000803 .
obo:GO_0006937 a rdfs:Class ;
rdfs:label "regulation of muscle contraction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of muscle contraction." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090257 .
obo:WBPhenotype_0001892 a rdfs:Class ;
rdfs:label "glycogen levels variant" ;
rdfs:comment "Any variation in the levels of the polymerized form of glucose throughout the body of the animal as compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0000546 a rdfs:Class ;
rdfs:label "early eggs laid" ;
rdfs:comment "Eggs are laid at an earlier stage of development when compared with control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000005 , obo:WBPhenotype_0000439 .
obo:GO_0061063 a rdfs:Class ;
rdfs:label "positive regulation of nematode larval development" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ;
rdfs:subClassOf obo:GO_0048582 , obo:GO_0061062 , obo:GO_0065007 .
obo:CHEBI_29195 a rdfs:Class ;
rdfs:label "cyanate" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35352 , obo:CHEBI_36828 .
obo:WBPhenotype_0001291 a rdfs:Class ;
rdfs:label "social behavior variant" ;
rdfs:comment "Animals exhibit variations in actions and responses that occurs predominantly, or only, in individuals that are part of a group, from that observed for animals in a control group." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:CHEBI_38222 a rdfs:Class ;
rdfs:label "hydrocarbyl anion" ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:CHEBI_6835 a rdfs:Class ;
rdfs:label "methomyl" ;
rdfs:comment "A carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_22327 , obo:CHEBI_23003 .
obo:WBPhenotype_0000309 a rdfs:Class ;
rdfs:label "SDS sensitive dauer" ;
rdfs:comment "Any variation that decreases the ability of dauer larva to tolerate the exposure to sodium dodecyl sulfate (a detergent) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001546 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001705 a rdfs:Class ;
rdfs:label "nucleocytoplasmic transport defective" ;
rdfs:comment "The directed movement of molecules between the nucleus and the cytoplasm is impaired." ;
rdfs:subClassOf obo:WBPhenotype_0001283 .
obo:CHEBI_33704 a rdfs:Class ;
rdfs:label "alpha-amino acid" ;
rdfs:comment "An amino acid in which the amino group is located on the carbon atom at the position α to the carboxy group." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:WBPhenotype_0001973 a rdfs:Class ;
rdfs:label "germ cell compartment size variant" ;
rdfs:comment "Any variation in germ cell compartment size compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001969 .
obo:WBPhenotype_0001499 a rdfs:Class ;
rdfs:label "meiotic chromosome segregation variant" ;
rdfs:comment "Variations in the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000773 .
obo:WBPhenotype_0001425 a rdfs:Class ;
rdfs:label "receptor mediated endocytosis defective" ;
rdfs:comment "Animals exhibit defects in the cell-mediated uptake of external materials via receptor activity. Receptor-mediated endocytosis ensures specificity of transport and generally occurs via clathrin-coated pits and vesicles. In C. elegans, this is often judged by the lack of yolk uptake in oocytes." ;
rdfs:subClassOf obo:WBPhenotype_0001422 , obo:WBPhenotype_0001424 .
obo:GO_0005102 a rdfs:Class ;
rdfs:label "signaling receptor binding" ;
rdfs:comment "Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." ;
rdfs:subClassOf obo:GO_0005515 .
obo:GO_1901588 a rdfs:Class ;
rdfs:label "dendritic microtubule" ;
rdfs:comment "Any microtubule in a dendrite, a neuron projection." ;
rdfs:subClassOf obo:GO_0005874 .
obo:GO_1901988 a rdfs:Class ;
rdfs:label "negative regulation of cell cycle phase transition" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0065007 , obo:GO_1901987 .
obo:WBPhenotype_0002211 a rdfs:Class ;
rdfs:label "phasmid neuron dye filling defect" ;
rdfs:comment "Animals exhibit defects in dye-filling of the neuronal cells of the phasmid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." ;
rdfs:subClassOf obo:WBPhenotype_0000257 , obo:WBPhenotype_0002535 .
obo:GO_0007320 a rdfs:Class ;
rdfs:label "insemination" ;
rdfs:comment "The introduction of semen or sperm into the genital tract of a female." ;
rdfs:subClassOf obo:GO_0044703 , obo:GO_0044706 , obo:GO_0048609 .
obo:GO_0051054 a rdfs:Class ;
rdfs:label "positive regulation of DNA metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." ;
rdfs:subClassOf obo:GO_0010604 , obo:GO_0051052 , obo:GO_0065007 .
obo:WBPhenotype_0002110 a rdfs:Class ;
rdfs:label "RME-1 recycling endosome morphology variant" ;
rdfs:comment "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
rdfs:subClassOf obo:WBPhenotype_0002093 .
obo:WBPhenotype_0000189 a rdfs:Class ;
rdfs:label "hypodermis disorganized" ;
rdfs:comment "Hypodermal cells fail to be organized in the same manner as observed in control animals. In C. elegans, hypodermal cells typically organize into distinct dorsal, lateral and ventral rows and cover the entire body." ;
rdfs:subClassOf obo:WBPhenotype_0000703 .
obo:GO_0050877 a rdfs:Class ;
rdfs:label "nervous system process" ;
rdfs:comment "An organ system process carried out by any of the organs or tissues of the neurological system." ;
rdfs:subClassOf obo:GO_0003008 .
obo:WBPhenotype_0000861 a rdfs:Class ;
rdfs:label "body wall muscle development variant" ;
rdfs:comment "Any variation in the progression of the principal muscle cell type whose contractile activity generates body motion in the nematode over time compared to control. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000921 , obo:WBPhenotype_0001292 .
obo:GO_0030174 a rdfs:Class ;
rdfs:label "regulation of DNA-templated DNA replication initiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090329 .
obo:WBPhenotype_0001561 a rdfs:Class ;
rdfs:label "dauer inner labial sensillum variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2." ;
rdfs:subClassOf obo:WBPhenotype_0001532 , obo:WBPhenotype_0001557 .
obo:WBPhenotype_0001915 a rdfs:Class ;
rdfs:label "mRNA expression ectopic" ;
rdfs:comment "Any variation that results in the cellular expression of an mRNA in cells/tissues, that is otherwise not observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000114 .
obo:CHEBI_173084 a rdfs:Class ;
rdfs:label "ferroptosis inhibitor" ;
rdfs:comment "Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms." ;
rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 .
obo:WBPhenotype_0000136 a rdfs:Class ;
rdfs:label "mRNA levels increased" ;
rdfs:comment "Animals exhibit elevated levels of messenger RNA compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000114 .
obo:WBPhenotype_0004005 a rdfs:Class ;
rdfs:label "pre hermaphrodite contact variant" ;
rdfs:comment "Males exhibit variations in mating behavior prior to contacting its mate compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000648 .
obo:CHEBI_62081 a rdfs:Class ;
rdfs:label "1,1-diunsubstituted alkanesulfonate" ;
rdfs:comment "An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_134249 .
obo:WBPhenotype_0000759 a rdfs:Class ;
rdfs:label "spindle defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000764 , obo:WBPhenotype_0001100 , obo:WBPhenotype_0002414 .
obo:PATO_0000133 a rdfs:Class ;
rdfs:label "orientation" ;
rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's placement which is defined by the angle between the bearer and an axis, or the angle between the bearer and another object." ;
rdfs:subClassOf obo:PATO_0000140 .
obo:GO_0009414 a rdfs:Class ;
rdfs:label "response to water deprivation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0009415 .
obo:WBPhenotype_0000272 a rdfs:Class ;
rdfs:label "egg laying irregular" ;
rdfs:comment "The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate does not conform to the pattern observed in control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000640 .
obo:WBPhenotype_0000783 a rdfs:Class ;
rdfs:label "M line absent" ;
rdfs:comment "Animals lack the planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001891 .
obo:CHEBI_76812 a rdfs:Class ;
rdfs:label "EC 2.7.11.* (protein-serine/threonine kinase) inhibitor" ;
rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*)." ;
rdfs:subClassOf obo:CHEBI_37699 .
obo:WBPhenotype_0001368 a rdfs:Class ;
rdfs:label "spermatheca absent" ;
rdfs:comment "Animals lack the somatic gonad structure that connects the distal gonad arm to the uterus." ;
rdfs:subClassOf obo:WBPhenotype_0001662 , obo:WBPhenotype_0002551 .
obo:WBPhenotype_0000799 a rdfs:Class ;
rdfs:label "anterior region development variant" ;
rdfs:comment "Variations in the progression of an animal's anatomy contained in the anterior region over time, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000578 .
obo:GO_1905897 a rdfs:Class ;
rdfs:label "regulation of response to endoplasmic reticulum stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080135 .
obo:WBPhenotype_0000062 a rdfs:Class ;
rdfs:label "lethal" ;
rdfs:comment "Animals die prematurely at any stage of the life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000531 .
obo:CHEBI_29067 a rdfs:Class ;
rdfs:label "carboxylic acid anion" ;
rdfs:comment "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_35406 .
obo:WBPhenotype_0000445 a rdfs:Class ;
rdfs:label "yolk synthesis in males" ;
rdfs:comment "Males generate yolk, the nutrient protein, normally produced and secreted by hermaphrodite or female intestinal cells." ;
rdfs:subClassOf obo:WBPhenotype_0000416 .
obo:CHEBI_83057 a rdfs:Class ;
rdfs:label "Daphnia metabolite" ;
rdfs:comment "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" ;
rdfs:subClassOf obo:CHEBI_83039 .
obo:PATO_0002323 a rdfs:Class ;
rdfs:label "temporal distribution quality" ;
rdfs:comment "A temporal distribution pattern of process occurrences within a regulation/reference process." ;
rdfs:subClassOf obo:PATO_0002062 .
obo:GO_0031129 a rdfs:Class ;
rdfs:label "inductive cell-cell signaling" ;
rdfs:comment "Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate." ;
rdfs:subClassOf obo:GO_0031128 .
obo:WBPhenotype_0001836 a rdfs:Class ;
rdfs:label "eggshell morphology variant" ;
rdfs:comment "Any variation in the overall structure or appearance of the protective barrier which isolates the embryo from the external environment, compared to control ." ;
rdfs:subClassOf obo:WBPhenotype_0000037 , obo:WBPhenotype_0002558 .
obo:CHEBI_77024 a rdfs:Class ;
rdfs:label "EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor" ;
rdfs:comment "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41)." ;
rdfs:subClassOf obo:CHEBI_76775 .
obo:WBPhenotype_0002421 a rdfs:Class ;
rdfs:label "cold resistant" ;
rdfs:comment "Animals exhibit increased ability to survive at low temperatures compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000146 .
obo:CHEBI_50491 a rdfs:Class ;
rdfs:label "haloalkyl group" ;
rdfs:comment "A group derived from a haloalkane by removal of a hydrogen atom." ;
rdfs:subClassOf obo:CHEBI_33249 .
obo:WBPhenotype_0000564 a rdfs:Class ;
rdfs:label "echo defecation cycle" ;
rdfs:comment "Muscle contractions that make up the defecation motor program are repeated before the onset of the next cycle unlike in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000207 .
obo:GO_1903573 a rdfs:Class ;
rdfs:label "negative regulation of response to endoplasmic reticulum stress" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0048585 , obo:GO_0065007 , obo:GO_1905897 .
obo:WBPhenotype_0000748 a rdfs:Class ;
rdfs:label "asymmetric cell division defective early emb" ;
rdfs:comment "Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes)." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0001585 .
obo:WBPhenotype_0001414 a rdfs:Class ;
rdfs:label "male mating defective" ;
rdfs:comment "Males exhibit defects in the specific actions or reactions that are associated with reproduction." ;
rdfs:subClassOf obo:WBPhenotype_0000648 .
obo:GO_0042069 a rdfs:Class ;
rdfs:label "regulation of catecholamine metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." ;
rdfs:subClassOf obo:GO_0033238 , obo:GO_0065007 , obo:GO_0080090 .
obo:GO_0043412 a rdfs:Class ;
rdfs:label "macromolecule modification" ;
rdfs:comment "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." ;
rdfs:subClassOf obo:GO_0043170 .
obo:PATO_0000374 a rdfs:Class ;
rdfs:label "increased distance" ;
rdfs:comment "A distance which is greater relative to the normal or average." ;
rdfs:subClassOf obo:PATO_0000040 , obo:PATO_0002305 .
obo:WBPhenotype_0001346 a rdfs:Class ;
rdfs:label "actin cytoskeleton dynamics phenotype" ;
rdfs:comment "Any variation in the dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001587 .
obo:GO_0050794 a rdfs:Class ;
rdfs:label "regulation of cellular process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:WBbt_0003711 a rdfs:Class ;
rdfs:label "metacorpus" ;
rdfs:comment "posterior segment of pharyngeal corpus." ;
rdfs:subClassOf obo:WBbt_0005789 .
obo:CL_0000000 a rdfs:Class ;
rdfs:label "cell" ;
rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:WBPhenotype_0002094 a rdfs:Class ;
rdfs:label "RAB-11 recycling endosome morphology variant" ;
rdfs:comment "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
rdfs:subClassOf obo:WBPhenotype_0002093 .
obo:GO_0000212 a rdfs:Class ;
rdfs:label "meiotic spindle organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0007051 , obo:GO_1903046 .
obo:WBPhenotype_0001807 a rdfs:Class ;
rdfs:label "alternative splicing variant" ;
rdfs:comment "Any variation in the process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000028 .
obo:WBPhenotype_0002586 a rdfs:Class ;
rdfs:label "reduced predatory feeding behavior"@en ;
rdfs:comment "Pristionchus pacificus: Animals exhibit reduced predatory feeding behavior, indicated by reduced predation success, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002585 .
obo:WBPhenotype_0002505 a rdfs:Class ;
rdfs:label "pathogen infection clearance variant"@en ;
rdfs:comment "Infected animals exhibit variations in the clearance of pathogen infection compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002164 .
obo:CHEBI_51151 a rdfs:Class ;
rdfs:label "dipolar compound" ;
rdfs:comment "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." ;
rdfs:subClassOf obo:CHEBI_72695 .
obo:WBPhenotype_0001355 a rdfs:Class ;
rdfs:label "gonad morphology variant" ;
rdfs:comment "Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000605 , obo:WBPhenotype_0002553 .
obo:GO_0090233 a rdfs:Class ;
rdfs:label "negative regulation of spindle checkpoint" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090231 , obo:GO_1901977 .
obo:GO_0071216 a rdfs:Class ;
rdfs:label "cellular response to biotic stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." ;
rdfs:subClassOf obo:GO_0009607 , obo:GO_0051716 .
obo:PATO_0000404 a rdfs:Class ;
rdfs:label "coiled" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the bearer's being curled or wound (especially in concentric rings or spirals)." ;
rdfs:subClassOf obo:PATO_0001794 .
obo:CHEBI_22333 a rdfs:Class ;
rdfs:label "alkylating agent" ;
rdfs:comment "Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases." ;
rdfs:subClassOf obo:CHEBI_25435 .
obo:WBPhenotype_0001082 a rdfs:Class ;
rdfs:label "large cytoplasmic granules early emb" ;
rdfs:comment "Abnormally large granules are observed in the cytoplasm of P0." ;
rdfs:subClassOf obo:WBPhenotype_0001081 .
obo:WBPhenotype_0001153 a rdfs:Class ;
rdfs:label "pronuclear migration failure early emb" ;
rdfs:comment "Neither of the pronuclei migrate and they never meet." ;
rdfs:subClassOf obo:WBPhenotype_0001152 .
obo:GO_1905167 a rdfs:Class ;
rdfs:label "positive regulation of lysosomal protein catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904352 , obo:GO_1905165 .
obo:GO_0033044 a rdfs:Class ;
rdfs:label "regulation of chromosome organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:WBPhenotype_0002051 a rdfs:Class ;
rdfs:label "ascaroside biosynthesis variant" ;
rdfs:comment "The production or regulation of ascaroside molecule populations differs from that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:CHEBI_25696 a rdfs:Class ;
rdfs:label "organic anion" ;
rdfs:comment "Any organic ion with a net negative charge." ;
rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_25699 .
obo:CHEBI_35662 a rdfs:Class ;
rdfs:label "terpenoid fundamental parent" ;
rdfs:subClassOf obo:CHEBI_35507 .
obo:WBPhenotype_0001272 a rdfs:Class ;
rdfs:label "vulval cell induction variant" ;
rdfs:comment "Vulval precursor cells inappropriately adopt fates that are normally restricted to other vulval precursor cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000220 .
obo:CHEBI_16247 a rdfs:Class ;
rdfs:label "phospholipid" ;
rdfs:comment "A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides." ;
rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_25703 , obo:CHEBI_37734 .
obo:WBbt_0006761 a rdfs:Class ;
rdfs:label "head muscle" ;
rdfs:comment "body wall muscle in the head, including first eight cells of each muscle quadrants which are innervated by nerve ring neurons." ;
rdfs:subClassOf obo:WBbt_0005813 .
obo:WBPhenotype_0001746 a rdfs:Class ;
rdfs:label "tight junction defective" ;
rdfs:comment "Any perturbation in the belt-like region of very close contact between the plasma membranes of adjacent cells that results in the complete occlusion of the intercellular space." ;
rdfs:subClassOf obo:WBPhenotype_0001658 .
obo:PATO_0002266 a rdfs:Class ;
rdfs:label "3-D shape" ;
rdfs:comment "A shape that inheres in a 3 dimensional entity." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:WBPhenotype_0002364 a rdfs:Class ;
rdfs:label "axonal degeneration" ;
rdfs:comment "Spontaneous axon breaks leading to degeneration of separated segments." ;
rdfs:subClassOf obo:WBPhenotype_0000179 , obo:WBPhenotype_0000180 .
obo:WBPhenotype_0002625 a rdfs:Class ;
rdfs:label "head degeneration"@en ;
rdfs:comment "Animals exhibit visible, structural degeneration of the head, unlike control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000071 .
obo:WBPhenotype_0001519 a rdfs:Class ;
rdfs:label "posterior cell migration variant" ;
rdfs:comment "Any variation in the orderly movement of cells along the posterior axis of the animal (abolished, misdirected or incomplete) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000594 .
obo:GO_0048477 a rdfs:Class ;
rdfs:label "oogenesis" ;
rdfs:comment "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0007281 , obo:GO_0007292 .
obo:GO_0031982 a rdfs:Class ;
rdfs:label "vesicle" ;
rdfs:comment "Any small, fluid-filled, spherical organelle enclosed by membrane." ;
rdfs:subClassOf obo:GO_0043227 .
obo:GO_0046785 a rdfs:Class ;
rdfs:label "microtubule polymerization" ;
rdfs:comment "The addition of tubulin heterodimers to one or both ends of a microtubule." ;
rdfs:subClassOf obo:GO_0031109 , obo:GO_0051258 , obo:GO_0097435 .
obo:GO_0042048 a rdfs:Class ;
rdfs:label "olfactory behavior" ;
rdfs:comment "The behavior of an organism in response to an odor." ;
rdfs:subClassOf obo:GO_0007635 .
obo:WBPhenotype_0001876 a rdfs:Class ;
rdfs:label "centriole biogenesis variant" ;
rdfs:comment "Any variation in the formation or disassembly of the cylindrical structures that are composed of groupings of microtubules found close to the nucleus (centrioles) compared to control. Centrioles are arranged perpendicularly and are surrounded by an amorphous mass of dense material (the pericentriolar material). The centrioles and the pericentriolar material constitute the compound structure known as the centrosome." ;
rdfs:subClassOf obo:WBPhenotype_0001903 .
obo:CHEBI_43254 a rdfs:Class ;
rdfs:label "(4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one" ;
rdfs:subClassOf obo:CHEBI_38337 .
obo:WBPhenotype_0001560 a rdfs:Class ;
rdfs:label "obsolete dauer sensory system plug variant" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000114 a rdfs:Class ;
rdfs:label "mRNA expression variant" ;
rdfs:comment "Variations in the biogenesis and stability of messenger RNA molecules compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:PATO_0001651 a rdfs:Class ;
rdfs:label "decreased resistance to" ;
rdfs:comment "A resistance to a stimulus which is relatively low." ;
rdfs:subClassOf obo:PATO_0001178 , obo:PATO_0002303 .
obo:CHEBI_15347 a rdfs:Class ;
rdfs:label "acetone" ;
rdfs:comment "A methyl ketone that consists of propane bearing an oxo group at C2." ;
rdfs:subClassOf obo:CHEBI_134179 , obo:CHEBI_26292 , obo:CHEBI_51867 , obo:CHEBI_73693 .
obo:WBPhenotype_0000682 a rdfs:Class ;
rdfs:label "feminization of germline" ;
rdfs:comment "Hermaphrodites are transformed into fertile females; In C. elegans, XO fog animals are somatically male but produce oocytes instead of, or in addition to, sperm." ;
rdfs:subClassOf obo:WBPhenotype_0000687 , obo:WBPhenotype_0000812 .
obo:CHEBI_26020 a rdfs:Class ;
rdfs:label "phosphate" ;
rdfs:comment "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." ;
rdfs:subClassOf obo:CHEBI_26079 .
obo:WBPhenotype_0001474 a rdfs:Class ;
rdfs:label "pyrazine chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of pyrazine. In C. elegans, at specific concentrations, pyrazine is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001466 .
obo:GO_0007283 a rdfs:Class ;
rdfs:label "spermatogenesis" ;
rdfs:comment "The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0048232 .
obo:GO_1905866 a rdfs:Class ;
rdfs:label "positive regulation of Atg1/ULK1 kinase complex assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly." ;
rdfs:subClassOf obo:GO_0031334 , obo:GO_0065007 , obo:GO_1905864 .
obo:CHEBI_64203 a rdfs:Class ;
rdfs:label "methiothepin" ;
rdfs:comment "A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively)." ;
rdfs:subClassOf obo:CHEBI_35683 , obo:CHEBI_38924 , obo:CHEBI_46845 .
obo:WBPhenotype_0000242 a rdfs:Class ;
rdfs:label "body elongation defective" ;
rdfs:comment "The epidermal cells of the embryo fail to elongate. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm." ;
rdfs:subClassOf obo:WBPhenotype_0001478 .
obo:WBPhenotype_0001795 a rdfs:Class ;
rdfs:label "microsatellite instability" ;
rdfs:comment "Animals exhibit variations in repeat lengths of microsatellite genomic sequences compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000000 .
obo:PATO_0001908 a rdfs:Class .
obo:WBPhenotype_0000084 a rdfs:Class ;
rdfs:label "L4 arrest" ;
rdfs:comment "The developmental program of the animals does not continue past the fourth larval stage (L4)." ;
rdfs:subClassOf obo:WBPhenotype_0000056 , obo:WBPhenotype_0000754 .
obo:CHEBI_35238 a rdfs:Class ;
rdfs:label "amino-acid zwitterion" ;
rdfs:comment "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:WBPhenotype_0002040 a rdfs:Class ;
rdfs:label "asymmetric chromosome segregation" ;
rdfs:comment "Chromosomes are not segregated symmetrically during mitosis." ;
rdfs:subClassOf obo:WBPhenotype_0001378 .
obo:PATO_0002014 a rdfs:Class ;
rdfs:label "structure, cavities" ;
rdfs:comment "A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:WBPhenotype_0001999 a rdfs:Class ;
rdfs:label "conflicting sensory integration variant" ;
rdfs:comment "Animals behave differently from control animals in assays testing for the ability to resolve or respond to conflicting sensory inputs." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:WBPhenotype_0000327 a rdfs:Class ;
rdfs:label "corpus contraction defect" ;
rdfs:comment "Any defect in the muscle contractions of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000747 .
obo:WBPhenotype_0001029 a rdfs:Class ;
rdfs:label "patchy coloration" ;
rdfs:comment "Animals exhibit an uneven distribution of biochromes or any other substances that cause disparate transparency/translucency compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000527 .
obo:GO_0006897 a rdfs:Class ;
rdfs:label "endocytosis" ;
rdfs:comment "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." ;
rdfs:subClassOf obo:GO_0016192 , obo:GO_0098657 .
obo:WBPhenotype_0000406 a rdfs:Class ;
rdfs:label "lumpy" ;
rdfs:comment "Animals have protrusions or bumps on their exterior which are not characteristic of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000535 .
obo:GO_0022407 a rdfs:Class ;
rdfs:label "regulation of cell-cell adhesion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." ;
rdfs:subClassOf obo:GO_0030155 , obo:GO_0065007 .
obo:WBPhenotype_0000610 a rdfs:Class ;
rdfs:label "excretory system physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000609 .
obo:CHEBI_472805 a rdfs:Class ;
rdfs:label "ouabain" ;
rdfs:comment "A steroid hormone that is a multi-hydroxylated α-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na+/K+-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus ." ;
rdfs:subClassOf obo:CHEBI_19129 , obo:CHEBI_26764 , obo:CHEBI_27848 , obo:CHEBI_36862 , obo:CHEBI_38092 , obo:CHEBI_38195 .
obo:WBPhenotype_0002375 a rdfs:Class ;
rdfs:label "reversion of swimming paralysis" ;
rdfs:comment "Animals that exhibit paralysis (reduced thrashing) revert back to normal swimming behavior that can be tabulated as a reversion index (number revertants/number paralysis) and reversion probability (time in reversion/time after paralysis)." ;
rdfs:subClassOf obo:WBPhenotype_0002114 .
obo:CHEBI_193111 a rdfs:Class ;
rdfs:label "methylcarbamate" ;
rdfs:comment "The conjugate base of methylcarbamic acid; major microspecies at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_37022 .
obo:WBPhenotype_0002054 a rdfs:Class ;
rdfs:label "magnesium hypersensitivity" ;
rdfs:comment "Animals exhibit an exaggerated response to magnesium compared to control animals exposed to similar concentrations." ;
rdfs:subClassOf obo:WBPhenotype_0000591 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000887 a rdfs:Class ;
rdfs:label "hermaphrodite behavior variant" ;
rdfs:comment "Animals exhibit variations in hermaphrodite-specific behaviors compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000821 .
obo:WBPhenotype_0002436 a rdfs:Class ;
rdfs:label "high susceptibility to induced DNA damage" ;
rdfs:comment "Nematodes exposed to DNA damaging agents or conditions exhibit greater susceptibility to DNA damage than other animals." ;
rdfs:subClassOf obo:WBPhenotype_0000739 .
obo:WBPhenotype_0000361 a rdfs:Class ;
rdfs:label "lima bean arrest" ;
rdfs:comment "Cessation of development at an intermediate stage in embryogenesis, immediately following the completion of gastrulation. In C. elegans this occurs around 350-390 minutes after first cleavage, cell number is at approximately 560 cells. At this time cell proliferation ceases and the embryo begins morphogenesis and elongation. The shape of the entire embryo within the eggshell resembles a lima bean (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000867 .
obo:WBPhenotype_0002459 a rdfs:Class ;
rdfs:label "hyperinduction of antimicrobial peptide expression after infection" ;
rdfs:comment "Animals exhibit hyperinduction of expression of an antimicrobial peptide after an infection, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001800 , obo:WBPhenotype_0002539 .
obo:WBPhenotype_0000956 a rdfs:Class ;
rdfs:label "lumbar ganglia development variant" ;
rdfs:comment "Any variation in the progression of the left and right lumbar ganglia which lie behind the pre-anal ganglion in the tail, in lateral positions over time from its initial formation to its mature form compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000943 .
obo:WBPhenotype_0000289 a rdfs:Class ;
rdfs:label "uterus morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001335 , obo:WBPhenotype_0002556 .
obo:WBPhenotype_0001727 a rdfs:Class ;
rdfs:label "body width variant" ;
rdfs:comment "Animals vary in the distance between dorsal and ventral sides when measured across the body at right angles to the length, from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000231 .
obo:WBPhenotype_0002263 a rdfs:Class ;
rdfs:label "mitochondrial membrane potential increased" ;
rdfs:comment "Any increase in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001282 .
obo:GO_1905639 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial mRNA catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process." ;
rdfs:subClassOf obo:GO_0000962 , obo:GO_0061014 , obo:GO_0065007 , obo:GO_1905637 .
obo:WBPhenotype_0000633 a rdfs:Class ;
rdfs:label "axon branching variant" ;
rdfs:comment "Animals display variations in the number or pattern of axonal tracts stemming from the neuron cell body, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000180 , obo:WBPhenotype_0001224 .
obo:WBbt_0005759 a rdfs:Class ;
rdfs:label "sensory neuron" ;
rdfs:comment "neuron that senses external stimuli and transduce them to signals internal to the organism." ;
rdfs:subClassOf obo:WBbt_0003679 .
obo:GO_0007611 a rdfs:Class ;
rdfs:label "learning or memory" ;
rdfs:comment "The acquisition and processing of information and/or the storage and retrieval of this information over time." ;
rdfs:subClassOf obo:GO_0007610 , obo:GO_0050890 .
obo:GO_0030017 a rdfs:Class ;
rdfs:label "sarcomere" ;
rdfs:comment "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_50584 a rdfs:Class ;
rdfs:label "alkyl alcohol" ;
rdfs:comment "An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position." ;
rdfs:subClassOf obo:CHEBI_2571 .
obo:GO_0034606 a rdfs:Class ;
rdfs:label "response to hermaphrodite contact" ;
rdfs:comment "The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate." ;
rdfs:subClassOf obo:GO_0060179 .
obo:WBPhenotype_0001154 a rdfs:Class ;
rdfs:label "paternal pronucleus migrates early emb" ;
rdfs:comment "Instead of the maternal pronucleus migrating to the posterior end of the one-cell embryo, the paternal pronucleus migrates to meet the maternal pronucleus in the anterior end." ;
rdfs:subClassOf obo:WBPhenotype_0001152 .
obo:WBPhenotype_0002002 a rdfs:Class ;
rdfs:label "supernumerary centrosomes" ;
rdfs:comment "A cell or cell of the animal exhibits extra centrosomes (a subcellular body consisting of two centrioles embedded in a protein matrix) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001903 .
obo:WBPhenotype_0002195 a rdfs:Class ;
rdfs:label "food dependent growth variant" ;
rdfs:comment "Animals exhibit variations in growth rate or the outcome of growth in response to food compared to control. In C. elegans, animals exhibit an increase or decrease in growth rate depending on the type of bacteria they are fed." ;
rdfs:subClassOf obo:WBPhenotype_0001072 .
obo:CHEBI_29438 a rdfs:Class ;
rdfs:label "methanide" ;
rdfs:subClassOf obo:CHEBI_38222 .
obo:GO_0035882 a rdfs:Class ;
rdfs:label "defecation rhythm" ;
rdfs:comment "The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated." ;
rdfs:subClassOf obo:GO_0007624 .
obo:PATO_0001046 a rdfs:Class ;
rdfs:label "resistance to" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's disposition to resist to a stimulus." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:WBPhenotype_0001774 a rdfs:Class ;
rdfs:label "gut on the exterior" ;
rdfs:comment "An epidermal enclosure defect that results in internal organs lying on the outside of the embryo." ;
rdfs:subClassOf obo:WBPhenotype_0000047 .
obo:WBPhenotype_0001616 a rdfs:Class ;
rdfs:label "trimethadione resistant" ;
rdfs:comment "Animals fail to respond to the concentration of trimethadione, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001615 .
obo:WBPhenotype_0001904 a rdfs:Class ;
rdfs:label "manganese toxicity resistant" ;
rdfs:comment "Animals fail to exhibit toxicity to the concentration of manganese that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to manganese include dopamine (DA) neuron neurodegeneration." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001863 .
obo:WBPhenotype_0000794 a rdfs:Class ;
rdfs:label "posterior body thin" ;
rdfs:comment "The posterior part of the worm exhibits a reduced girth compared to a control animal of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0000793 .
obo:GO_0060341 a rdfs:Class ;
rdfs:label "regulation of cellular localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." ;
rdfs:subClassOf obo:GO_0032879 , obo:GO_0050794 , obo:GO_0065007 .
obo:CHEBI_22478 a rdfs:Class ;
rdfs:label "amino alcohol" ;
rdfs:comment "An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group." ;
rdfs:subClassOf obo:CHEBI_30879 , obo:CHEBI_50047 .
obo:WBPhenotype_0000006 a rdfs:Class ;
rdfs:label "egg laying defective" ;
rdfs:comment "Eggs are not laid, laid at a slower rate or eggs are laid at a later stage of development compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000640 .
obo:GO_0003367 a rdfs:Class ;
rdfs:label "cell-cell adhesion involved in ameboidal cell migration" ;
rdfs:comment "The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells." ;
rdfs:subClassOf obo:GO_0098609 .
obo:WBPhenotype_0000073 a rdfs:Class ;
rdfs:label "tail morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any portion of the most posterior region of the body compared to control. The anterior bound of the tail is not well defined though it might range from the position of the post-deirids to the opening of the anus (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000532 , obo:WBPhenotype_0000582 .
obo:GO_0043292 a rdfs:Class ;
rdfs:label "contractile muscle fiber" ;
rdfs:comment "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." ;
rdfs:subClassOf obo:GO_0043232 , obo:GO_0099512 .
obo:WBPhenotype_0002144 a rdfs:Class ;
rdfs:label "mitochondrial respiratory complex I variant" ;
rdfs:comment "The protein complex located in the mitochondrial inner membrane that is the first entry point for electrons into the electron transport chain and catalyzes proton translocation coupled to the oxidation of NADH by ubiquinone, differs in activity, composition, or organization from that of controls." ;
rdfs:subClassOf obo:WBPhenotype_0002142 .
obo:GO_0044770 a rdfs:Class ;
rdfs:label "cell cycle phase transition" ;
rdfs:comment "The cell cycle process by which a cell commits to entering the next cell cycle phase." ;
rdfs:subClassOf obo:GO_0022402 .
obo:WBPhenotype_0000800 a rdfs:Class ;
rdfs:label "posterior region development variant" ;
rdfs:comment "Variations in the progression of an animal's anatomy contained in the posterior region over time, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000578 .
obo:WBPhenotype_0001216 a rdfs:Class ;
rdfs:label "meiosis metaphase to anaphase transition block" ;
rdfs:comment "Oocyte chromosomes arrest in metaphase of meiosis I without transitioning to anaphase or producing polar bodies." ;
rdfs:subClassOf obo:WBPhenotype_0000775 , obo:WBPhenotype_0001496 .
obo:WBPhenotype_0001599 a rdfs:Class ;
rdfs:label "ouabain resistant" ;
rdfs:comment "Animals fail to respond to the concentration of ouabain that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, resistance to ouabain is often assayed via body contraction response." ;
rdfs:subClassOf obo:WBPhenotype_0000331 , obo:WBPhenotype_0001502 .
obo:WBPhenotype_0001958 a rdfs:Class ;
rdfs:label "gonad degenerate" ;
rdfs:comment "Animals contain a gonad that initially functioned, but subsequently stopped. In hermaphrodites or females there is often the presence old embryos and/or hatched larva, but no young embryos, in the uterus." ;
rdfs:subClassOf obo:WBPhenotype_0001355 .
obo:WBPhenotype_0000622 a rdfs:Class ;
rdfs:label "muscle system development variant" ;
rdfs:comment "Any variation in the progression of the muscle system over time, from its formation to its mature state compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000530 .
obo:GO_0044785 a rdfs:Class ;
rdfs:label "metaphase/anaphase transition of meiotic cell cycle" ;
rdfs:comment "The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis." ;
rdfs:subClassOf obo:GO_0044771 , obo:GO_0044784 .
obo:WBPhenotype_0002448 a rdfs:Class ;
rdfs:label "enhanced acute pharyngeal pumping response to light" ;
rdfs:comment "Animals exhibit an enhanced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a greater extent than in controls during the first 0-5 seconds after light exposure onset." ;
rdfs:subClassOf obo:WBPhenotype_0002447 .
obo:WBPhenotype_0000903 a rdfs:Class ;
rdfs:label "marginal cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of marginal cells compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000899 .
obo:PATO_0000274 a rdfs:Class ;
rdfs:label "fertility" ;
rdfs:comment "A reproductive quality inhering in a bearer by virtue of the bearer's initiating, sustaining, or supporting reproduction." ;
rdfs:subClassOf obo:PATO_0001434 .
obo:CHEBI_27364 a rdfs:Class ;
rdfs:label "zinc molecular entity" ;
rdfs:subClassOf obo:CHEBI_33673 .
obo:CL_0002319 a rdfs:Class ;
rdfs:label "neural cell" ;
rdfs:comment "A cell that is part of the nervous system." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_0032271 a rdfs:Class ;
rdfs:label "regulation of protein polymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0065007 .
obo:WBPhenotype_0000261 a rdfs:Class ;
rdfs:label "amphid sheath secretion failure" ;
rdfs:comment "Amphid sheath cells lack the ability to secrete vesicles and their contents within the amphid pocket." ;
rdfs:subClassOf obo:WBPhenotype_0000260 .
obo:GO_0042177 a rdfs:Class ;
rdfs:label "negative regulation of protein catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0042176 , obo:GO_0051248 , obo:GO_0065007 .
obo:WBPhenotype_0000417 a rdfs:Class ;
rdfs:label "cell division failure" ;
rdfs:comment "The process of physical partitioning and separation of a cell into daughter cells is abolished." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:WBPhenotype_0001194 a rdfs:Class ;
rdfs:label "extra and ectopic neuron" ;
rdfs:comment "Animals have one or more extra neurons, which are present in places they are normally not found, when compared to the number and location of these neurons in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001303 .
obo:GO_0014043 a rdfs:Class ;
rdfs:label "negative regulation of neuron maturation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." ;
rdfs:subClassOf obo:GO_0014041 , obo:GO_0065007 , obo:GO_1903430 .
obo:GO_0051345 a rdfs:Class ;
rdfs:label "positive regulation of hydrolase activity" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." ;
rdfs:subClassOf obo:GO_0043085 , obo:GO_0051336 , obo:GO_0065007 .
obo:GO_0044818 a rdfs:Class ;
rdfs:label "mitotic G2/M transition checkpoint" ;
rdfs:comment "A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0007093 , obo:GO_0010972 .
obo:WBPhenotype_0002341 a rdfs:Class ;
rdfs:label "bent posture variant" ;
rdfs:comment "Animals exhibit variations in instantaneous posture with regards to eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends." ;
rdfs:subClassOf obo:WBPhenotype_0001703 .
obo:WBbt_0006840 a rdfs:Class ;
rdfs:label "cholinergic neuron" ;
rdfs:comment "neuron that uses vesicular acetylcholine as a neurotransmitter." ;
rdfs:subClassOf obo:WBbt_0003679 .
obo:WBPhenotype_0002013 a rdfs:Class ;
rdfs:label "univalent meiotic chromosomes" ;
rdfs:comment "Chromosomes fails to pair with homologous chromosomes during the prophase stage of meiosis." ;
rdfs:subClassOf obo:WBPhenotype_0002012 .
obo:GO_0010558 a rdfs:Class ;
rdfs:label "negative regulation of macromolecule biosynthetic process" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0010556 , obo:GO_0010605 , obo:GO_0065007 .
obo:PATO_0002198 a rdfs:Class ;
rdfs:label "quality of a substance" ;
rdfs:comment "A quality inhering in a bearer by virtue of its constitution." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:WBPhenotype_0000872 a rdfs:Class ;
rdfs:label "obsolete connected mitochodria muscle" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000894 a rdfs:Class ;
rdfs:label "germ cell differentiation variant" ;
rdfs:comment "Variations in the ability of a relatively unspecialized cell to acquire the specialized features of a mature gamete compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000774 .
obo:WBPhenotype_0000517 a rdfs:Class ;
rdfs:label "behavior phenotype" ;
rdfs:comment "Variations in the specific actions or reactions in response to external or internal stimuli compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000519 .
obo:GO_0048856 a rdfs:Class ;
rdfs:label "anatomical structure development" ;
rdfs:comment "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ;
rdfs:subClassOf obo:GO_0032502 .
obo:PATO_0001625 a rdfs:Class ;
rdfs:label "increased functionality" ;
rdfs:comment "A functional quality held by the bearer when the latter exhibits increased ability to perform a regular function(s)." ;
rdfs:subClassOf obo:PATO_0001510 , obo:PATO_0001559 .
obo:WBPhenotype_0000788 a rdfs:Class ;
rdfs:label "anterior pale" ;
rdfs:comment "Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the anterior body axis compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000971 , obo:WBPhenotype_0001261 .
obo:WBbt_0005753 a rdfs:Class ;
rdfs:label "seam cell" ;
rdfs:comment "a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail" ;
rdfs:subClassOf obo:WBbt_0007846 .
obo:WBPhenotype_0000999 a rdfs:Class ;
rdfs:label "athermotactic" ;
rdfs:comment "The responses of an animal towards temperature are not influenced by its cultivation temperature." ;
rdfs:subClassOf obo:WBPhenotype_0000478 .
obo:WBPhenotype_0002278 a rdfs:Class ;
rdfs:label "acute functional tolerance to alcohol defective" ;
rdfs:comment "Animals do not develop acute functional tolerance to alcohol after a short exposure, unlike that observed in control animals" ;
rdfs:subClassOf obo:WBPhenotype_0000555 .
obo:GO_1903466 a rdfs:Class ;
rdfs:label "regulation of mitotic DNA replication initiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication." ;
rdfs:subClassOf obo:GO_0030174 , obo:GO_0065007 , obo:GO_1903463 .
obo:PATO_0002265 a rdfs:Class ;
rdfs:label "behavioural activity" ;
rdfs:comment "A behavioral quality of a process inhering in a bearer by virtue of the bearer's disposition to exhibit marked activity." ;
rdfs:subClassOf obo:PATO_0000186 .
obo:BFO_0000023 a rdfs:Class ;
rdfs:label "role"@en ;
rdfs:comment "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts."@en ;
rdfs:subClassOf obo:BFO_0000017 .
obo:WBPhenotype_0002641 a rdfs:Class ;
rdfs:label "cuticle permeability increased"@en ;
rdfs:comment "The cuticle of animals becomes more permeable to dyes or stains, such as Hoechst 33258, or other substances compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002640 .
obo:WBPhenotype_0001575 a rdfs:Class ;
rdfs:label "ATP levels reduced" ;
rdfs:comment "Animals exhibit a decrease in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." ;
rdfs:subClassOf obo:WBPhenotype_0001574 .
obo:CHEBI_49637 a rdfs:Class ;
rdfs:label "hydrogen atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_24835 , obo:CHEBI_25585 , obo:CHEBI_33559 .
obo:CHEBI_35293 a rdfs:Class ;
rdfs:label "fused compound" ;
rdfs:comment "A polycyclic compound that contains more than one ring with at least two common atoms (also known as bridgehead carbons) that are adjacent to each other." ;
rdfs:subClassOf obo:CHEBI_33635 .
obo:WBPhenotype_0001057 a rdfs:Class ;
rdfs:label "lithium chemotaxis defective" ;
rdfs:comment "Animals fail to exhibit the same taxis behavior as control animals in response to lithium. In C. elegans, this is characterized by the failure to move towards lithium." ;
rdfs:subClassOf obo:WBPhenotype_0001440 .
obo:GO_0051333 a rdfs:Class ;
rdfs:label "meiotic nuclear membrane reassembly" ;
rdfs:comment "The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs." ;
rdfs:subClassOf obo:GO_0031468 , obo:GO_1903046 .
obo:CHEBI_38808 a rdfs:Class ;
rdfs:label "calcium channel modulator" ;
rdfs:comment "A membrane transport modulator that is able to regulate intracellular calcium levels." ;
rdfs:subClassOf obo:CHEBI_38632 .
obo:WBPhenotype_0002491 a rdfs:Class ;
rdfs:label "ectopic neurite outgrowth"@en ;
rdfs:comment "Neurons exhibit neurite outgrowth in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0000572 .
obo:CHEBI_26401 a rdfs:Class ;
rdfs:label "purines" ;
rdfs:comment "A class of imidazopyrimidines that consists of purine and its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_35875 .
obo:GO_0061064 a rdfs:Class ;
rdfs:label "negative regulation of nematode larval development" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ;
rdfs:subClassOf obo:GO_0048581 , obo:GO_0061062 , obo:GO_0065007 .
obo:WBPhenotype_0002200 a rdfs:Class ;
rdfs:label "oviduct muscle defective" ;
rdfs:comment "Variations in the progression of the muscles of the adult hermaphrodite oviduct over time from their initial formation to their mature structure compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000282 .
obo:WBPhenotype_0000017 a rdfs:Class ;
rdfs:label "aldicarb resistant" ;
rdfs:comment "Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000680 , obo:WBPhenotype_0001289 , obo:WBPhenotype_0001502 .
obo:WBPhenotype_0001335 a rdfs:Class ;
rdfs:label "hermaphrodite reproductive system morphology variant" ;
rdfs:comment "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the hermaphrodite reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." ;
rdfs:subClassOf obo:WBPhenotype_0000605 .
obo:WBPhenotype_0002155 a rdfs:Class ;
rdfs:label "pre miRNA processing defective" ;
rdfs:comment "The production of mature miRNA from pre-miRNA is significantly deficient compared to controls. Deficiencies in this process can result in the accumulation of pre-miRNA species and or the absence or smaller amount of mature miRNA compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000028 , obo:WBPhenotype_0002528 .
obo:CHEBI_59888 a rdfs:Class ;
rdfs:label "gamma-aminobutyric acid zwitterion" ;
rdfs:comment "Zwitterionic form of γ-aminobutyric acid having an anionic carboxy group and a protonated amino group." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:GO_0016477 a rdfs:Class ;
rdfs:label "cell migration" ;
rdfs:comment "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." ;
rdfs:subClassOf obo:GO_0048870 .
obo:GO_1903749 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to mitochondrion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to mitochondrion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903747 , obo:GO_1903829 .
obo:WBPhenotype_0000830 a rdfs:Class ;
rdfs:label "B lineage variant" ;
rdfs:comment "The descendants of the B cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000809 .
obo:GO_0006858 a rdfs:Class ;
rdfs:label "extracellular transport" ;
rdfs:comment "The transport of substances that occurs outside cells." ;
rdfs:subClassOf obo:GO_0006810 .
obo:WBPhenotype_0001496 a rdfs:Class ;
rdfs:label "metaphase to anaphase transition defect" ;
rdfs:comment "Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle." ;
rdfs:subClassOf obo:WBPhenotype_0000740 .
obo:CHEBI_35522 a rdfs:Class ;
rdfs:label "beta-adrenergic agonist" ;
rdfs:comment "An agent that selectively binds to and activates β-adrenergic receptors." ;
rdfs:subClassOf obo:CHEBI_37886 , obo:CHEBI_48540 .
obo:GO_0000087 a rdfs:Class ;
rdfs:label "mitotic M phase" ;
rdfs:comment "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0000279 , obo:GO_0098763 .
obo:WBPhenotype_0001463 a rdfs:Class ;
rdfs:label "cAMP chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of cAMP." ;
rdfs:subClassOf obo:WBPhenotype_0001053 .
obo:CHEBI_25676 a rdfs:Class ;
rdfs:label "oligopeptide" ;
rdfs:comment "A peptide containing a relatively small number of amino acids." ;
rdfs:subClassOf obo:CHEBI_16670 .
obo:GO_0015630 a rdfs:Class ;
rdfs:label "microtubule cytoskeleton" ;
rdfs:comment "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." ;
rdfs:subClassOf obo:GO_0005856 .
obo:CHEBI_23114 a rdfs:Class ;
rdfs:label "chloride salt" ;
rdfs:subClassOf obo:CHEBI_23117 , obo:CHEBI_33958 .
obo:GO_0016236 a rdfs:Class ;
rdfs:label "macroautophagy" ;
rdfs:comment "The autophagic process that proceeds via the formation of an autophagosome." ;
rdfs:subClassOf obo:GO_0006914 .
obo:GO_0032387 a rdfs:Class ;
rdfs:label "negative regulation of intracellular transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0048523 , obo:GO_0051051 , obo:GO_0065007 .
obo:WBPhenotype_0001735 a rdfs:Class ;
rdfs:label "muscle cell activity variant" ;
rdfs:comment "Animals exhibit variations in the frequency, rate or extent of muscle contraction compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000990 .
obo:GO_0009306 a rdfs:Class ;
rdfs:label "protein secretion" ;
rdfs:comment "The controlled release of proteins from a cell." ;
rdfs:subClassOf obo:GO_0015031 , obo:GO_0032940 , obo:GO_0035592 , obo:GO_0071692 .
obo:WBPhenotype_0000557 a rdfs:Class ;
rdfs:label "dopamine adaptation defective" ;
rdfs:comment "Animals do not exhibit decreased responsiveness after prolonged or repeated exposure to dopamine." ;
rdfs:subClassOf obo:WBPhenotype_0000556 .
obo:CHEBI_78840 a rdfs:Class ;
rdfs:label "olefinic compound" ;
rdfs:comment "Any organic molecular entity that contains at least one C=C bond." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:WBPhenotype_0000774 a rdfs:Class ;
rdfs:label "gametogenesis variant" ;
rdfs:comment "Any variation in the processes that govern the generation and maintenance of gametes compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000529 , obo:WBPhenotype_0000624 .
obo:PATO_0000004 a rdfs:Class ;
rdfs:label "mobility" ;
rdfs:comment "A quality of inhering in a bearer by virtue of the bearer's disposition to move freely." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:WBPhenotype_0000030 a rdfs:Class ;
rdfs:label "growth variant" ;
rdfs:comment "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:PATO_0001584 a rdfs:Class ;
rdfs:label "increased variability" ;
rdfs:comment "A variability which is relatively high." ;
rdfs:subClassOf obo:PATO_0001227 , obo:PATO_0002300 .
obo:WBPhenotype_0000541 a rdfs:Class ;
rdfs:label "cord commissures fail to reach target" ;
rdfs:comment "Axon tracts fail to complete the connection between nerve cords. In C. elegans, these tracts grow circumferentially around the animal, completing the connection between the ventral and dorsal nerve cords." ;
rdfs:subClassOf obo:WBPhenotype_0000014 .
obo:CHEBI_16236 a rdfs:Class ;
rdfs:label "ethanol" ;
rdfs:comment "A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_134179 , obo:CHEBI_23982 , obo:CHEBI_50584 .
obo:CHEBI_77035 a rdfs:Class ;
rdfs:label "expectorant" ;
rdfs:comment "Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:WBPhenotype_0000597 a rdfs:Class ;
rdfs:label "tail behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of the tail in response to external or internal stimuli compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000580 .
obo:WBls_0000818 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during L1 larval stage"@en ;
rdfs:comment "A C. elegans life stage that occurs during the L1 larval life stage" ;
rdfs:subClassOf obo:WBls_0000817 .
obo:GO_1903186 a rdfs:Class ;
rdfs:label "regulation of vitellogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vitellogenesis." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0051239 , obo:GO_0065007 .
obo:WBls_0000823 a rdfs:Class ;
rdfs:label "C. elegans life stage by number of cells"@en ;
rdfs:comment "C. elegans life stage classified by the number of cells in the organism." ;
rdfs:subClassOf obo:WBls_0000825 .
obo:WBPhenotype_0000734 a rdfs:Class ;
rdfs:label "hypodermal cell physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the hypodermal system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000986 .
obo:GO_0110166 a rdfs:Class ;
rdfs:label "DNA synthesis involved in mitochondrial DNA replication" ;
rdfs:comment "Any DNA biosynthetic process that is involved in mitochondrial DNA replication." ;
rdfs:subClassOf obo:GO_0032042 , obo:GO_0071897 , obo:GO_0090592 .
obo:WBPhenotype_0002184 a rdfs:Class ;
rdfs:label "starvation induced apoptosis variant" ;
rdfs:comment "Any variation in the amount of cells undergoing apoptosis in organism as a result of deprivation of nourishment, compared to control. In C. elegans, starvation normally causes increased apoptosis." ;
rdfs:subClassOf obo:WBPhenotype_0000147 , obo:WBPhenotype_0000730 .
obo:WBPhenotype_0000581 a rdfs:Class ;
rdfs:label "body axis morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of a discrete axis (dorsal/ventral/anterior/posterior/transverse) of their anatomy, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000532 .
obo:GO_0120035 a rdfs:Class ;
rdfs:label "regulation of plasma membrane bounded cell projection organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." ;
rdfs:subClassOf obo:GO_0031344 , obo:GO_0065007 .
obo:CHEBI_22221 a rdfs:Class ;
rdfs:label "acyl group" ;
rdfs:comment "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l ≠ 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:WBPhenotype_0000322 a rdfs:Class ;
rdfs:label "nose rounded" ;
rdfs:comment "The extreme anterior part of the body appears blunted in shape." ;
rdfs:subClassOf obo:WBPhenotype_0000321 .
obo:GO_0010269 a rdfs:Class ;
rdfs:label "response to selenium ion" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion." ;
rdfs:subClassOf obo:GO_0042221 .
obo:WBPhenotype_0001984 a rdfs:Class ;
rdfs:label "long range axon migration variant" ;
rdfs:comment "Animals exhibit axons with migration behaviors that differ from those observed in control animals after the axons cross a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords." ;
rdfs:subClassOf obo:WBPhenotype_0001224 .
obo:GO_0072686 a rdfs:Class ;
rdfs:label "mitotic spindle" ;
rdfs:comment "A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules." ;
rdfs:subClassOf obo:GO_0005819 .
obo:GO_0008150 a rdfs:Class ;
rdfs:label "biological_process" ;
rdfs:comment "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:GO_0031175 a rdfs:Class ;
rdfs:label "neuron projection development" ;
rdfs:comment "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ;
rdfs:subClassOf obo:GO_0120036 .
obo:WBPhenotype_0001030 a rdfs:Class ;
rdfs:label "pronuclear envelope defective early emb" ;
rdfs:comment "Any deficiency in the lipid bilayer, the equivalent of the nuclear envelope, that surrounds each pronucleus within gametes and within the early zygote after pronuclear reformation (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001151 .
obo:GO_0090169 a rdfs:Class ;
rdfs:label "regulation of spindle assembly" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090224 , obo:GO_1902115 .
obo:WBPhenotype_0000345 a rdfs:Class ;
rdfs:label "VPC cell division variant" ;
rdfs:comment "Any variation that alters the physical partitioning and separation of a vulval precursor cell into daughter cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:CL_0000021 a rdfs:Class ;
rdfs:label "female germ cell" ;
rdfs:comment "Female germ cell is a germ cell that supports female gamete production." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000586 .
obo:CHEBI_28659 a rdfs:Class ;
rdfs:label "phosphorus atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25585 , obo:CHEBI_33300 .
obo:CHEBI_64708 a rdfs:Class ;
rdfs:label "one-carbon compound" ;
rdfs:comment "An organic molecular entity containing a single carbon atom (C1)." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:GO_0007094 a rdfs:Class ;
rdfs:label "mitotic spindle assembly checkpoint signaling" ;
rdfs:comment "A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signaling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC)." ;
rdfs:subClassOf obo:GO_0045841 , obo:GO_0071173 , obo:GO_0071174 .
obo:GO_0048609 a rdfs:Class ;
rdfs:label "multicellular organismal reproductive process" ;
rdfs:comment "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." ;
rdfs:subClassOf obo:GO_0022414 .
obo:GO_0070382 a rdfs:Class ;
rdfs:label "exocytic vesicle" ;
rdfs:comment "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." ;
rdfs:subClassOf obo:GO_0030133 , obo:GO_0099503 .
obo:GO_0006836 a rdfs:Class ;
rdfs:label "neurotransmitter transport" ;
rdfs:comment "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." ;
rdfs:subClassOf obo:GO_0006810 .
obo:CHEBI_50996 a rdfs:Class ;
rdfs:label "tertiary amino compound" ;
rdfs:comment "A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:CHEBI_28024 a rdfs:Class ;
rdfs:label "cyanic acid" ;
rdfs:subClassOf obo:CHEBI_23423 , obo:CHEBI_64708 .
obo:WBPhenotype_0001481 a rdfs:Class ;
rdfs:label "thrashing increased" ;
rdfs:comment "The number of body thrashes within an aqueous environment in a given period of time is increased, compared with control worms." ;
rdfs:subClassOf obo:WBPhenotype_0001700 .
obo:GO_2001242 a rdfs:Class ;
rdfs:label "regulation of intrinsic apoptotic signaling pathway" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902531 , obo:GO_2001233 .
obo:GO_1905551 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to endoplasmic reticulum" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903828 , obo:GO_1905550 .
obo:WBPhenotype_0001001 a rdfs:Class ;
rdfs:label "dauer behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of dauer stage animals in response to external or internal stimuli compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000819 .
obo:PATO_0000077 a rdfs:Class ;
rdfs:label "response to" ;
rdfs:comment "A quality inhering in a bearer by virtue of the whether the bearer's disposition to react to a stimulus or an agent." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:GO_0098590 a rdfs:Class ;
rdfs:label "plasma membrane region" ;
rdfs:comment "A membrane that is a (regional) part of the plasma membrane." ;
rdfs:subClassOf obo:GO_0016020 .
obo:GO_0036477 a rdfs:Class ;
rdfs:label "somatodendritic compartment" ;
rdfs:comment "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0001469 a rdfs:Class ;
rdfs:label "butanone chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of butanone. In C. elegans, at specific concentrations, butanone is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001467 .
obo:WBPhenotype_0002474 a rdfs:Class ;
rdfs:label "viral resistance increased" ;
rdfs:comment "Animals are less prone to infection by virus compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001014 .
obo:CHEBI_16240 a rdfs:Class ;
rdfs:label "hydrogen peroxide" ;
rdfs:comment "An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond." ;
rdfs:subClassOf obo:CHEBI_24837 , obo:CHEBI_26523 .
obo:GO_0048699 a rdfs:Class ;
rdfs:label "generation of neurons" ;
rdfs:comment "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." ;
rdfs:subClassOf obo:GO_0022008 .
obo:WBPhenotype_0000865 a rdfs:Class ;
rdfs:label "amphid sheath cell physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for a amphid sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000849 , obo:WBPhenotype_0000975 .
obo:WBbt_0003679 a rdfs:Class ;
rdfs:label "neuron" ;
rdfs:comment "Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_0033242 a rdfs:Class ;
rdfs:label "negative regulation of amine catabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0033239 , obo:GO_0033241 , obo:GO_0065007 .
obo:GO_0072656 a rdfs:Class ;
rdfs:label "maintenance of protein location in mitochondrion" ;
rdfs:comment "Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0072595 .
obo:WBPhenotype_0000817 a rdfs:Class ;
rdfs:label "uterine vulval cell development variant" ;
rdfs:comment "Variations in the progression of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) over time from an initial condition to a later condition compared to control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000529 , obo:WBPhenotype_0000624 .
obo:GO_0005884 a rdfs:Class ;
rdfs:label "actin filament" ;
rdfs:comment "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." ;
rdfs:subClassOf obo:GO_0099513 .
obo:WBPhenotype_0001577 a rdfs:Class ;
rdfs:label "mitochondria alignment variant" ;
rdfs:comment "Animals exhibit variations in the parallel arrangement of mitochondria within a cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001576 .
obo:WBPhenotype_0000484 a rdfs:Class ;
rdfs:label "embryo small" ;
rdfs:comment "The organism's size during the embryonic developmental stage is decreased compared to that observed in control." ;
rdfs:subClassOf obo:WBPhenotype_0001136 .
obo:GO_0051960 a rdfs:Class ;
rdfs:label "regulation of nervous system development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000026 .
obo:CHEBI_48379 a rdfs:Class ;
rdfs:label "isourea" ;
rdfs:comment "A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives." ;
rdfs:subClassOf obo:CHEBI_48378 .
obo:CHEBI_59869 a rdfs:Class ;
rdfs:label "L-alpha-amino acid zwitterion" ;
rdfs:comment "Zwitterionic form of an L-α-amino acid having an anionic carboxy group and a protonated amino group." ;
rdfs:subClassOf obo:CHEBI_78608 .
obo:PATO_0001510 a rdfs:Class ;
rdfs:label "functional" ;
rdfs:comment "A functionality quality held by the bearer when the latter is able to perform a regular function(s)." ;
rdfs:subClassOf obo:PATO_0001509 .
obo:WBPhenotype_0001869 a rdfs:Class ;
rdfs:label "meiotic spindle positioning defective" ;
rdfs:comment "Cells undergoing meiosis exhibit defects in the positioning of the meiotic spindle." ;
rdfs:subClassOf obo:WBPhenotype_0001868 .
obo:CHEBI_3638 a rdfs:Class ;
rdfs:label "chloroquine" ;
rdfs:comment "An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis." ;
rdfs:subClassOf obo:CHEBI_36683 , obo:CHEBI_36709 , obo:CHEBI_50995 , obo:CHEBI_50996 .
obo:GO_0043233 a rdfs:Class ;
rdfs:label "organelle lumen" ;
rdfs:comment "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." ;
rdfs:subClassOf obo:GO_0031974 .
obo:WBPhenotype_0002149 a rdfs:Class ;
rdfs:label "X cluster small RNA expression variant" ;
rdfs:comment "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of the small X-chromosome derived RNAs (X cluster) species of small RNA." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:CHEBI_22260 a rdfs:Class ;
rdfs:label "adenosines" ;
rdfs:comment "Any purine ribonucleoside that is a derivative of adenosine." ;
rdfs:subClassOf obo:CHEBI_26399 .
obo:GO_0044281 a rdfs:Class ;
rdfs:label "small molecule metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." ;
rdfs:subClassOf obo:GO_0008152 .
obo:PATO_0000648 a rdfs:Class ;
rdfs:label "obstructed" ;
rdfs:comment "A morphological quality inhering in a bearer by virtue of the bearer's being blocked or filled with obstacles or an obstacle." ;
rdfs:subClassOf obo:PATO_0000608 .
obo:GO_0051640 a rdfs:Class ;
rdfs:label "organelle localization" ;
rdfs:comment "Any process in which an organelle is transported to, and/or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051179 .
obo:GO_1903047 a rdfs:Class ;
rdfs:label "mitotic cell cycle process" ;
rdfs:comment "A process that is part of the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0022402 .
obo:GO_0000184 a rdfs:Class ;
rdfs:label "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ;
rdfs:comment "The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins." ;
rdfs:subClassOf obo:GO_0000956 .
obo:PATO_0001422 a rdfs:Class ;
rdfs:label "dead" ;
rdfs:comment "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life." ;
rdfs:subClassOf obo:PATO_0000169 .
obo:GO_2000385 a rdfs:Class ;
rdfs:label "positive regulation of ectoderm development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of ectoderm development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_2000383 .
obo:GO_0051327 a rdfs:Class ;
rdfs:label "meiotic M phase" ;
rdfs:comment "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0000279 , obo:GO_0098762 .
obo:WBPhenotype_0001232 a rdfs:Class ;
rdfs:label "serotonin response variant" ;
rdfs:comment "Animals exhibit variations in the response to the addition of serotonin compared to that observed in control animals. Serotonin is a monoamine neurotransmitter." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0001944 a rdfs:Class ;
rdfs:label "oocyte number decreased" ;
rdfs:comment "A decreased number of celullarized haploid female germ cells (oocytes) are present in the gonad compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000186 , obo:WBPhenotype_0001260 .
obo:WBPhenotype_0001757 a rdfs:Class ;
rdfs:label "neuropeptide metabolism variant" ;
rdfs:comment "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of signalling peptides in the organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:GO_2000543 a rdfs:Class ;
rdfs:label "positive regulation of gastrulation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of gastrulation." ;
rdfs:subClassOf obo:GO_0010470 , obo:GO_0040019 , obo:GO_0065007 .
obo:CL_0000300 a rdfs:Class ;
rdfs:label "gamete" ;
rdfs:comment "A mature sexual reproductive cell having a single set of unpaired chromosomes." ;
rdfs:subClassOf obo:CL_0000413 , obo:CL_0000586 .
obo:CHEBI_60258 a rdfs:Class ;
rdfs:label "EC 3.4.* (hydrolases acting on peptide bond) inhibitor" ;
rdfs:comment "A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*)." ;
rdfs:subClassOf obo:CHEBI_76759 .
obo:WBbt_0005368 a rdfs:Class ;
rdfs:label "anterior spermatheca" ;
rdfs:comment "spermatheca in anterior gonad arm." ;
rdfs:subClassOf obo:WBbt_0005319 .
obo:GO_0005783 a rdfs:Class ;
rdfs:label "endoplasmic reticulum" ;
rdfs:comment "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ;
rdfs:subClassOf obo:GO_0043231 .
obo:WBPhenotype_0001431 a rdfs:Class ;
rdfs:label "pointed tail tip male" ;
rdfs:comment "Male tails fail to undergo tip retraction thereby forming a 'leptoderan' or 'pointed' adult tail." ;
rdfs:subClassOf obo:WBPhenotype_0000070 .
obo:CHEBI_27171 a rdfs:Class ;
rdfs:label "organic heterobicyclic compound" ;
rdfs:subClassOf obo:CHEBI_33672 , obo:CHEBI_38166 .
obo:WBPhenotype_0000521 a rdfs:Class ;
rdfs:label "pigmentation phenotype" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency." ;
rdfs:subClassOf obo:WBPhenotype_0000520 , obo:WBPhenotype_0002555 .
obo:WBPhenotype_0000047 a rdfs:Class ;
rdfs:label "gastrulation variant" ;
rdfs:comment "Variations in the process by which the germ layers become positioned in an embryo compared to control animals. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:GO_1904172 a rdfs:Class ;
rdfs:label "positive regulation of bleb assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of bleb assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120034 , obo:GO_1904170 .
obo:WBPhenotype_0002305 a rdfs:Class ;
rdfs:label "head movement increased" ;
rdfs:comment "Animals exhibit an increase in the movement of the most anterior portion of the body to a new location compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000595 , obo:WBPhenotype_0001265 .
obo:PATO_0001595 a rdfs:Class ;
rdfs:label "depth" ;
rdfs:comment "A 1-D extent quality inhering in a bearer by virtue of the bearer's downward or backward or inward dimension." ;
rdfs:subClassOf obo:PATO_0001708 .
obo:CHEBI_60643 a rdfs:Class ;
rdfs:label "NMDA receptor antagonist" ;
rdfs:comment "Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs." ;
rdfs:subClassOf obo:CHEBI_60798 .
obo:WBPhenotype_0001504 a rdfs:Class ;
rdfs:label "maternal effect sterile" ;
rdfs:comment "Sterility caused by aberrant maternal components required for normal postembryonic development and/or function of the germ line." ;
rdfs:subClassOf obo:WBPhenotype_0001037 .
obo:WBPhenotype_0000918 a rdfs:Class ;
rdfs:label "excretory socket cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the excretory socket cell compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000601 , obo:WBPhenotype_0000899 .
obo:WBbt_0005178 a rdfs:Class ;
rdfs:label "hermaphrodite gonad" ;
rdfs:comment "organ in hermaphrodite animal that produces both ova and sperm." ;
rdfs:subClassOf obo:WBbt_0005175 , obo:WBbt_0005758 .
obo:WBPhenotype_0001104 a rdfs:Class ;
rdfs:label "P0 spindle absent early emb" ;
rdfs:comment "No mitotic spindle is seen in P0." ;
rdfs:subClassOf obo:WBPhenotype_0001103 .
obo:GO_0032108 a rdfs:Class ;
rdfs:label "negative regulation of response to nutrient levels" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels." ;
rdfs:subClassOf obo:GO_0032107 , obo:GO_0048585 , obo:GO_0065007 .
obo:WBPhenotype_0000376 a rdfs:Class ;
rdfs:label "no uterine cavity" ;
rdfs:comment "Animals lack the inner space of the uterus through which the fertilized egg passes on its way out of the nematode via the vulva (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000289 .
obo:WBls_0000106 a rdfs:Class ;
rdfs:label "L1 larval stage" ;
rdfs:comment "The first stage larva of nematodes." ;
rdfs:subClassOf obo:WBls_0000105 .
obo:WBPhenotype_0001064 a rdfs:Class ;
rdfs:label "inactive phase long" ;
rdfs:comment "Animals display uncharacteristically long periods during which they do not lay eggs compared to control, usually based on the analysis of the distribution of the log intervals of egg-laying events. In C. elegans, long inactive phases can be observed in HSN-ablated and serotonin-deficient animals." ;
rdfs:subClassOf obo:WBPhenotype_0000006 , obo:WBPhenotype_0001066 .
obo:GO_0045770 a rdfs:Class ;
rdfs:label "positive regulation of asymmetric cell division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." ;
rdfs:subClassOf obo:GO_0009786 , obo:GO_0051781 , obo:GO_0065007 .
obo:GO_0120039 a rdfs:Class ;
rdfs:label "plasma membrane bounded cell projection morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." ;
rdfs:subClassOf obo:GO_0048858 .
obo:WBbt_0005342 a rdfs:Class ;
rdfs:label "uterine muscle" ;
rdfs:comment "muscle lining of the uterine wall." ;
rdfs:subClassOf obo:WBbt_0005758 , obo:WBbt_0005781 .
obo:GO_0003674 a rdfs:Class ;
rdfs:label "molecular_function" ;
rdfs:comment "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:WBPhenotype_0000648 a rdfs:Class ;
rdfs:label "male mating variant" ;
rdfs:comment "Any variation in the specific actions or reactions of the male that are associated with reproduction compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000647 , obo:WBPhenotype_0000888 .
obo:WBPhenotype_0001024 a rdfs:Class ;
rdfs:label "male morphology variant" ;
rdfs:comment "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a male in the population, from that observed for control males." ;
rdfs:subClassOf obo:WBPhenotype_0001023 , obo:WBPhenotype_0002555 .
obo:GO_0046958 a rdfs:Class ;
rdfs:label "nonassociative learning" ;
rdfs:comment "A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment." ;
rdfs:subClassOf obo:GO_0007612 .
obo:GO_0030100 a rdfs:Class ;
rdfs:label "regulation of endocytosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endocytosis." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0060627 , obo:GO_0065007 .
obo:WBPhenotype_0002619 a rdfs:Class ;
rdfs:label "cell death increased"@en ;
rdfs:comment "Animals exhibit increased occurrence of cell death, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000729 .
obo:GO_0051651 a rdfs:Class ;
rdfs:label "maintenance of location in cell" ;
rdfs:comment "Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0051235 .
obo:GO_1905951 a rdfs:Class ;
rdfs:label "mitochondrion DNA recombination" ;
rdfs:comment "Any DNA recombination that takes place in mitochondrion." ;
rdfs:subClassOf obo:GO_0006310 , obo:GO_0032042 .
obo:GO_0034599 a rdfs:Class ;
rdfs:label "cellular response to oxidative stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0006979 , obo:GO_0062197 .
obo:WBPhenotype_0000973 a rdfs:Class ;
rdfs:label "homologous recombination increased" ;
rdfs:comment "Animals exhibit an increased frequency of exchange of genetic material between non-sister chromatids of a pair of homologues." ;
rdfs:subClassOf obo:WBPhenotype_0000742 .
obo:WBPhenotype_0000286 a rdfs:Class ;
rdfs:label "embryo disorganized" ;
rdfs:comment "Embryos fail to be organized in the same manner as observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:CHEBI_83347 a rdfs:Class ;
rdfs:label "organosulfonic ester" ;
rdfs:comment "An ester resulting from the formal condensation of the hydroxy group of an alcohol, phenol, heteroarenol, or enol with an organosulfonic acid." ;
rdfs:subClassOf obo:CHEBI_33424 , obo:CHEBI_35701 .
obo:GO_0040025 a rdfs:Class ;
rdfs:label "vulval development" ;
rdfs:comment "The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ;
rdfs:subClassOf obo:GO_0048513 .
obo:GO_0045701 a rdfs:Class ;
rdfs:label "negative regulation of spermatid nuclear differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0045596 , obo:GO_0045700 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_2000242 .
obo:GO_0110029 a rdfs:Class ;
rdfs:label "negative regulation of meiosis I" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ;
rdfs:subClassOf obo:GO_0045835 , obo:GO_0060631 , obo:GO_0065007 .
obo:CHEBI_33249 a rdfs:Class ;
rdfs:label "organyl group" ;
rdfs:comment "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." ;
rdfs:subClassOf obo:CHEBI_51447 .
obo:CHEBI_41550 a rdfs:Class ;
rdfs:label "fluoroform" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_39281 .
obo:GO_0051169 a rdfs:Class ;
rdfs:label "nuclear transport" ;
rdfs:comment "The directed movement of substances into, out of, or within the nucleus." ;
rdfs:subClassOf obo:GO_0046907 .
obo:GO_0050769 a rdfs:Class ;
rdfs:label "positive regulation of neurogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0050767 , obo:GO_0051962 , obo:GO_0065007 .
obo:GO_0061523 a rdfs:Class ;
rdfs:label "cilium disassembly" ;
rdfs:comment "A cellular process that results in the breakdown of a cilium." ;
rdfs:subClassOf obo:GO_0044782 , obo:GO_1903008 .
obo:PATO_0000574 a rdfs:Class ;
rdfs:label "decreased length" ;
rdfs:comment "A length quality which is relatively small." ;
rdfs:subClassOf obo:PATO_0000122 , obo:PATO_0000587 .
obo:WBPhenotype_0001582 a rdfs:Class ;
rdfs:label "X linked gene expression reduced" ;
rdfs:comment "Levels of transcripts associated with genes on the X chromosome are decreased compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000718 .
obo:GO_0016050 a rdfs:Class ;
rdfs:label "vesicle organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." ;
rdfs:subClassOf obo:GO_0006996 .
obo:WBbt_0006783 a rdfs:Class ;
rdfs:label "blast cell" ;
rdfs:comment "precursor cell destined to divide some time after hatching." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_0045088 a rdfs:Class ;
rdfs:label "regulation of innate immune response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." ;
rdfs:subClassOf obo:GO_0002831 , obo:GO_0031347 , obo:GO_0032101 , obo:GO_0050776 , obo:GO_0065007 .
obo:WBPhenotype_0001250 a rdfs:Class ;
rdfs:label "amphid channel axoneme morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or composition of the microtuble-based fibrillar core, axoneme, of the cilia of the neurons that project through the sensillum pore to the outside of the animal, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000262 , obo:WBPhenotype_0001249 .
obo:GO_1901673 a rdfs:Class ;
rdfs:label "regulation of mitotic spindle assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic spindle assembly." ;
rdfs:subClassOf obo:GO_0060236 , obo:GO_0065007 , obo:GO_0090169 .
obo:GO_0090329 a rdfs:Class ;
rdfs:label "regulation of DNA-templated DNA replication" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized." ;
rdfs:subClassOf obo:GO_0006275 , obo:GO_0065007 .
obo:CHEBI_35683 a rdfs:Class ;
rdfs:label "aryl sulfide" ;
rdfs:comment "Any organic sulfide in which the sulfur is attached to at least one aromatic group." ;
rdfs:subClassOf obo:CHEBI_16385 .
obo:WBPhenotype_0000655 a rdfs:Class ;
rdfs:label "GABA synaptic transmission variant" ;
rdfs:comment "Animals exhibit variations in the process of GABA neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000584 .
obo:CHEBI_76710 a rdfs:Class ;
rdfs:label "EC 4.* (lyase) inhibitor" ;
rdfs:comment "An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C‒C, C‒O, C‒N and other bonds by other means than by hydrolysis or oxidation." ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:WBPhenotype_0001764 a rdfs:Class ;
rdfs:label "carbon dioxide response variant" ;
rdfs:comment "Animals exhibit variations in their response to carbon dioxide compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:GO_0035592 a rdfs:Class ;
rdfs:label "establishment of protein localization to extracellular region" ;
rdfs:comment "The directed movement of a protein to a specific location within the extracellular region." ;
rdfs:subClassOf obo:GO_0045184 .
obo:WBPhenotype_0001221 a rdfs:Class ;
rdfs:label "nose touch defective" ;
rdfs:comment "Animal fails to exhibit characteristic response after a nose-on collision with an object compared to control. In C. elegans, this is usually assayed with a hair or similar fiber. The nose is the anterior most tip of the animal." ;
rdfs:subClassOf obo:WBPhenotype_0000456 , obo:WBPhenotype_0004026 .
obo:WBPhenotype_0000066 a rdfs:Class ;
rdfs:label "XX lethal" ;
rdfs:comment "XX-bearing individuals die preferentially over other animals in the population. In C.elegans, XX animals die preferentially over X0 animals." ;
rdfs:subClassOf obo:WBPhenotype_0000064 .
obo:GO_0090297 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial DNA replication" ;
rdfs:comment "Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090296 , obo:GO_1901860 , obo:GO_2000105 .
obo:GO_0000375 a rdfs:Class ;
rdfs:label "RNA splicing, via transesterification reactions" ;
rdfs:comment "Splicing of RNA via a series of two transesterification reactions." ;
rdfs:subClassOf obo:GO_0008380 .
obo:CHEBI_25212 a rdfs:Class ;
rdfs:label "metabolite" ;
rdfs:comment "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." ;
rdfs:subClassOf obo:CHEBI_52206 .
obo:GO_0048102 a rdfs:Class ;
rdfs:label "autophagic cell death" ;
rdfs:comment "A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells." ;
rdfs:subClassOf obo:GO_0012501 .
obo:WBPhenotype_0002606 a rdfs:Class ;
rdfs:label "necrotic cell death decreased"@en ;
rdfs:comment "Animals exhibit reduced necrotic cell death, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000415 .
obo:WBPhenotype_0000532 a rdfs:Class ;
rdfs:label "body region morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of a discrete region of their anatomy compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000535 , obo:WBPhenotype_0002557 .
obo:WBPhenotype_0000248 a rdfs:Class ;
rdfs:label "obsolete sensory neuroanatomy variant" ;
rdfs:comment "OBSOLETE." .
obo:GO_0030071 a rdfs:Class ;
rdfs:label "regulation of mitotic metaphase/anaphase transition" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901990 , obo:GO_1902099 .
obo:WBPhenotype_0002469 a rdfs:Class ;
rdfs:label "plate tap habituation variant" ;
rdfs:comment "Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000626 .
obo:GO_1902116 a rdfs:Class ;
rdfs:label "negative regulation of organelle assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0065007 , obo:GO_1902115 .
obo:CHEBI_33253 a rdfs:Class ;
rdfs:label "nucleon" ;
rdfs:comment "Heavy nuclear particle: proton or neutron." ;
rdfs:subClassOf obo:CHEBI_36339 , obo:CHEBI_36347 .
obo:PATO_0002009 a rdfs:Class ;
rdfs:label "branchiness" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:GO_0072347 a rdfs:Class ;
rdfs:label "response to anesthetic" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation." ;
rdfs:subClassOf obo:GO_0042221 .
obo:WBbt_0008592 a rdfs:Class ;
rdfs:label "secondary spermatocyte" ;
rdfs:comment "A haploid immature germ cell which forms in the gonad by the division of a diploid primary spermatocyte. It undergoes a second meiotic division to complete meiosis, at which time the daughter cells detach from the residual body to become spermatids." ;
rdfs:subClassOf obo:WBbt_0006799 .
obo:WBPhenotype_0000822 a rdfs:Class ;
rdfs:label "sex determination variant" ;
rdfs:comment "Any variation in the processes that govern the sexually dimorphic development of germline or somatic tissue compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000930 .
obo:GO_0031644 a rdfs:Class ;
rdfs:label "regulation of nervous system process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." ;
rdfs:subClassOf obo:GO_0044057 , obo:GO_0065007 .
obo:PATO_0000585 a rdfs:Class ;
rdfs:label "hypotrophic" ;
rdfs:comment "A decreased size quality inhering in a bearer by virtue of the bearer's exhibiting reduced size of a cell or constituent group of cells (for example, organ)." ;
rdfs:subClassOf obo:PATO_0000596 .
obo:WBbt_0005740 a rdfs:Class ;
rdfs:label "midbody" ;
rdfs:comment "body region posterior to the head and anterior to the tail" ;
rdfs:subClassOf obo:WBbt_0005738 .
obo:WBPhenotype_0000356 a rdfs:Class ;
rdfs:label "spermatogenesis delayed" ;
rdfs:comment "The progression of immature germ cells to functional sperm is retarded compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000670 , obo:WBPhenotype_0000848 .
obo:CHEBI_51446 a rdfs:Class ;
rdfs:label "organic divalent group" ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:WBPhenotype_0001357 a rdfs:Class ;
rdfs:label "male gonad morphology variant" ;
rdfs:comment "Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male gametes compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001024 , obo:WBPhenotype_0001355 .
obo:WBls_0000001 a rdfs:Class ;
rdfs:label "free-living nematode stage" ;
rdfs:comment "The nematode life-cycle stage that occurs entirely outside of a host organism." ;
rdfs:subClassOf obo:WBls_0000101 .
obo:CHEBI_28868 a rdfs:Class ;
rdfs:label "fatty acid anion" ;
rdfs:comment "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid." ;
rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_35757 .
obo:WBPhenotype_0002529 a rdfs:Class ;
rdfs:label "proteasome defective"@en ;
rdfs:comment "Animals exhibit defects or impairments in the functioning of the proteasome." ;
rdfs:subClassOf obo:WBPhenotype_0002009 .
obo:CHEBI_35640 a rdfs:Class ;
rdfs:label "adrenergic uptake inhibitor" ;
rdfs:comment "Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin." ;
rdfs:subClassOf obo:CHEBI_37962 .
obo:WBPhenotype_0000091 a rdfs:Class ;
rdfs:label "epidermis muscle detached" ;
rdfs:comment "The cell(s) whose principal function is to provide contractile forces, is separated from the adjacent epidermis." ;
rdfs:subClassOf obo:WBPhenotype_0000076 , obo:WBPhenotype_0000475 .
obo:WBPhenotype_0002390 a rdfs:Class ;
rdfs:label "variable cell division timing" ;
rdfs:comment "Animals exhibit larger variations in cell division timing events than in controls." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:GO_0051046 a rdfs:Class ;
rdfs:label "regulation of secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:CHEBI_76413 a rdfs:Class ;
rdfs:label "greenhouse gas" ;
rdfs:comment "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:GO_0000323 a rdfs:Class ;
rdfs:label "lytic vacuole" ;
rdfs:comment "A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases." ;
rdfs:subClassOf obo:GO_0005773 .
obo:CHEBI_77941 a rdfs:Class ;
rdfs:label "EC 3.5.1.4 (amidase) inhibitor" ;
rdfs:comment "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." ;
rdfs:subClassOf obo:CHEBI_76807 .
obo:WBPhenotype_0001419 a rdfs:Class ;
rdfs:label "emetine hypersensitive" ;
rdfs:comment "Animals respond to emetine at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001131 a rdfs:Class ;
rdfs:label "loose mitotic furrow early emb" ;
rdfs:comment "Once formed, the mitotic furrow can \"slide\"laterally." ;
rdfs:subClassOf obo:WBPhenotype_0001129 .
obo:GO_0070972 a rdfs:Class ;
rdfs:label "protein localization to endoplasmic reticulum" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum." ;
rdfs:subClassOf obo:GO_0033365 .
obo:WBPhenotype_0001839 a rdfs:Class ;
rdfs:label "phorbol ester resistant" ;
rdfs:comment "Animals fail to respond to the concentration of phorbol esters that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Phorbol esters such as PMA act as DAG mimetics." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 .
obo:GO_0070585 a rdfs:Class ;
rdfs:label "protein localization to mitochondrion" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within the mitochondrion." ;
rdfs:subClassOf obo:GO_0033365 .
obo:WBPhenotype_0001288 a rdfs:Class ;
rdfs:comment "OBSOLETE." .
obo:CHEBI_76816 a rdfs:Class ;
rdfs:label "EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor" ;
rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category." ;
rdfs:subClassOf obo:CHEBI_76668 .
obo:WBPhenotype_0001724 a rdfs:Class ;
rdfs:label "tunicamycin hypersensitive" ;
rdfs:comment "Animals respond to tunicamycin at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000359 , obo:WBPhenotype_0001918 .
obo:CHEBI_25223 a rdfs:Class ;
rdfs:label "methanesulfonate ester" ;
rdfs:comment "An organosulfonic ester resulting from the formal condensation of methanesulfonic acid with the hydroxy group of an alcohol, phenol, heteroarenol, or enol." ;
rdfs:subClassOf obo:CHEBI_48544 , obo:CHEBI_83347 .
obo:WBPhenotype_0000660 a rdfs:Class ;
rdfs:label "social feeding increased" ;
rdfs:comment "Worms are found in clumps and/or crowded at the border of the bacterial lawn more frequently than control animals. This behavior is not due to mobility defects." ;
rdfs:subClassOf obo:WBPhenotype_0000659 , obo:WBPhenotype_0001291 .
obo:PATO_0001930 a rdfs:Class ;
rdfs:label "variant shape" ;
rdfs:comment "A quality inhering in a bearer by virtue the bearer's having or exhibiting variation its shape." ;
rdfs:subClassOf obo:PATO_0001929 .
obo:RO_0002503 a rdf:Property ;
rdfs:label "towards" ;
rdfs:comment "q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2" ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002502 .
obo:WBPhenotype_0000859 a rdfs:Class ;
rdfs:label "excretory socket cell development variant" ;
rdfs:comment "Variations in the progression of an interfacial epithelial cell which links excretory duct to hypodermis, over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000621 .
obo:WBPhenotype_0001458 a rdfs:Class ;
rdfs:label "chloride chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of chloride." ;
rdfs:subClassOf obo:WBPhenotype_0001052 .
obo:WBPhenotype_0002281 a rdfs:Class ;
rdfs:label "organism osmotic stress hypersensitive" ;
rdfs:comment "Animals exhibit hypersensitivty to osmotic stress compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000876 .
obo:CHEBI_60911 a rdfs:Class ;
rdfs:label "racemate" ;
rdfs:comment "A racemate is an equimolar mixture of a pair of enantiomers." ;
rdfs:subClassOf obo:CHEBI_60004 .
obo:WBPhenotype_0004030 a rdfs:Class ;
rdfs:label "male response to hermaphrodite variant" ;
rdfs:comment "Any variation in the response by the male to a hermaphrodite after initial contact following mate finding compared to control. In C. elegans the male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate." ;
rdfs:subClassOf obo:WBPhenotype_0000648 , obo:WBPhenotype_0004029 .
obo:WBPhenotype_0001828 a rdfs:Class ;
rdfs:label "RNAi persistence variant" ;
rdfs:comment "Variations in the persistence of an RNAi induced phenotype compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:CHEBI_58945 a rdfs:Class ;
rdfs:label "organophosphate oxoanion" ;
rdfs:comment "An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_26079 .
obo:WBPhenotype_0001302 a rdfs:Class ;
rdfs:label "P granule localization defective" ;
rdfs:comment "The restricted localization of P granules to germ cells or germ cell precursors is altered compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001301 .
obo:GO_1903431 a rdfs:Class ;
rdfs:label "positive regulation of cell maturation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell maturation." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0065007 , obo:GO_1903429 .
obo:WBPhenotype_0000925 a rdfs:Class ;
rdfs:label "sex muscle morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the sex muscles compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000923 .
obo:WBPhenotype_0001102 a rdfs:Class ;
rdfs:label "mitotic spindle defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a mitotic cell cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000759 .
obo:WBls_0000013 a rdfs:Class ;
rdfs:label "enclosing embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 290-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage when embryo just finished gastrulation and is enclosing." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000815 .
obo:CHEBI_17883 a rdfs:Class ;
rdfs:label "hydrogen chloride" ;
rdfs:comment "A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms." ;
rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18140 , obo:CHEBI_23117 , obo:CHEBI_37176 .
obo:CHEBI_67114 a rdfs:Class ;
rdfs:label "ryanodine receptor agonist" ;
rdfs:comment "A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction." ;
rdfs:subClassOf obo:CHEBI_38809 .
obo:WBPhenotype_0002334 a rdfs:Class ;
rdfs:label "track length decreased" ;
rdfs:comment "Animals exhibit decreased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope." ;
rdfs:subClassOf obo:WBPhenotype_0002332 .
obo:BFO_0000016 a rdfs:Class ;
rdfs:label "disposition"@en ;
rdfs:subClassOf obo:BFO_0000017 .
obo:WBPhenotype_0002646 a rdfs:Class ;
rdfs:label "thermorecovery reduced"@en ;
rdfs:comment "Animals exhibit reduced recovery from heat stress compared to controls. Reduced recovery may be indicated, for example, by a decrease in normal movement, such as uncoordinated or jerky movement or paralysis, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002645 .
obo:WBPhenotype_0002357 a rdfs:Class ;
rdfs:label "metabolite content increased" ;
rdfs:comment "Animals exhibit an increase in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism." ;
rdfs:subClassOf obo:WBPhenotype_0000463 .
obo:WBPhenotype_0000806 a rdfs:Class ;
rdfs:label "hermaphrodite fertility variant" ;
rdfs:comment "Hermaphrodites exhibit variations in the time of onset or duration of the fertile period, or variations in the production of viable offspring, including number and state of fertilized eggs laid, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000145 .
obo:CHEBI_35702 a rdfs:Class ;
rdfs:label "diethyl ether" ;
rdfs:comment "An ether in which the oxygen atom is linked to two ethyl groups." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_134179 , obo:CHEBI_25698 .
obo:WBPhenotype_0004001 a rdfs:Class ;
rdfs:label "hermaphrodite mating variant" ;
rdfs:comment "Any variation in the specific actions or reactions of a hermaphrodite during mating compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000647 , obo:WBPhenotype_0000887 .
obo:GO_2000301 a rdfs:Class ;
rdfs:label "negative regulation of synaptic vesicle exocytosis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903306 , obo:GO_2000300 .
obo:WBPhenotype_0002439 a rdfs:Class ;
rdfs:label "repetitive transgene expression increased" ;
rdfs:comment "Animals exhibit increased expression of repetitive exogenous DNA compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002437 .
obo:WBPhenotype_0000185 a rdfs:Class ;
rdfs:label "apoptosis protracted" ;
rdfs:comment "Animals exhibit a decreased pace of the programmed cell death pathway, compared to that observed for control cells." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:CHEBI_85046 a rdfs:Class ;
rdfs:label "skin lightening agent" ;
rdfs:comment "Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin." ;
rdfs:subClassOf obo:CHEBI_64857 .
obo:GO_0050764 a rdfs:Class ;
rdfs:label "regulation of phagocytosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." ;
rdfs:subClassOf obo:GO_0030100 , obo:GO_0065007 .
obo:GO_0005912 a rdfs:Class ;
rdfs:label "adherens junction" ;
rdfs:comment "A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules." ;
rdfs:subClassOf obo:GO_0005911 .
obo:GO_0000278 a rdfs:Class ;
rdfs:label "mitotic cell cycle" ;
rdfs:comment "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." ;
rdfs:subClassOf obo:GO_0007049 .
obo:PATO_0000591 a rdfs:Class ;
rdfs:label "increased thickness" ;
rdfs:comment "A thickness which is relatively high." ;
rdfs:subClassOf obo:PATO_0000586 , obo:PATO_0000915 .
obo:WBPhenotype_0002414 a rdfs:Class ;
rdfs:label "spindle variant" ;
rdfs:comment "Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000746 , obo:WBPhenotype_0001588 .
obo:GO_0048589 a rdfs:Class ;
rdfs:label "developmental growth" ;
rdfs:comment "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." ;
rdfs:subClassOf obo:GO_0040007 .
obo:GO_1902532 a rdfs:Class ;
rdfs:label "negative regulation of intracellular signal transduction" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." ;
rdfs:subClassOf obo:GO_0009968 , obo:GO_0065007 , obo:GO_1902531 .
obo:WBPhenotype_0001977 a rdfs:Class ;
rdfs:label "germ cell partition morphology variant" ;
rdfs:comment "Any variation in the form or composition of the compartment partitions in the germline of females/hermaphrodites that exist when nuclei are still connected to a common cytoplasm (rachis), compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001969 .
obo:WBPhenotype_0002493 a rdfs:Class ;
rdfs:label "ectopic cell"@en ;
rdfs:comment "Animals exhibit one or more cells of a particular type in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0000529 , obo:WBPhenotype_0002552 .
obo:WBPhenotype_0000615 a rdfs:Class ;
rdfs:label "cilia morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals. In C. elegans, cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of control animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of control animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside." ;
rdfs:subClassOf obo:WBPhenotype_0001526 , obo:WBPhenotype_0002089 .
obo:GO_0001667 a rdfs:Class ;
rdfs:label "ameboidal-type cell migration" ;
rdfs:comment "Cell migration that is accomplished by extension and retraction of a pseudopodium." ;
rdfs:subClassOf obo:GO_0016477 .
obo:CHEBI_42485 a rdfs:Class ;
rdfs:label "formyl group" ;
rdfs:subClassOf obo:CHEBI_27207 .
obo:GO_1902742 a rdfs:Class ;
rdfs:label "apoptotic process involved in development" ;
rdfs:comment "Any apoptotic process that is involved in anatomical structure development." ;
rdfs:subClassOf obo:GO_0006915 .
obo:WBPhenotype_0001858 a rdfs:Class ;
rdfs:label "suppression of head oscillations defective" ;
rdfs:comment "Animals fail to suppress head oscillations in response to anterior touch. In C. elegans, this behavior is a result of tyraminergic signaling." ;
rdfs:subClassOf obo:WBPhenotype_0000595 .
obo:CHEBI_61951 a rdfs:Class ;
rdfs:label "microtubule-destabilising agent" ;
rdfs:comment "Any substance that interacts with tubulin to inhibit polymerisation of microtubules." ;
rdfs:subClassOf obo:CHEBI_60832 , obo:CHEBI_64911 .
obo:WBPhenotype_0000984 a rdfs:Class ;
rdfs:label "posterior pigmentation variant" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the posterior body axis compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000786 .
obo:WBPhenotype_0000058 a rdfs:Class ;
rdfs:label "late larval lethal" ;
rdfs:comment "Animals die during late larval development. In C. elegans, this occurs during the L3- L4 larval stages of the life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000054 .
obo:PATO_0001495 a rdfs:Class ;
rdfs:label "notched" ;
rdfs:comment "A concave quality inhering in a bearer by virtue of the bearer's shape being a V-shaped cut." ;
rdfs:subClassOf obo:PATO_0001857 .
obo:PATO_0000911 a rdfs:Class ;
rdfs:label "decreased rate" ;
rdfs:comment "A rate which is relatively low." ;
rdfs:subClassOf obo:PATO_0000161 , obo:PATO_0002302 .
obo:WBPhenotype_0000226 a rdfs:Class ;
rdfs:label "serotonin catabolism defective" ;
rdfs:comment "Animals are unable to carry out any chemical reaction or pathway resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter." ;
rdfs:subClassOf obo:WBPhenotype_0000222 .
obo:WBPhenotype_0002043 a rdfs:Class ;
rdfs:label "hermaphrodite mating efficiency reduced" ;
rdfs:comment "The number of cross progeny produced by hermaphrodites is reduced compared to control hermaphrodites." ;
rdfs:subClassOf obo:WBPhenotype_0004001 .
obo:WBPhenotype_0001243 a rdfs:Class ;
rdfs:label "intraflagellar transport distance short" ;
rdfs:comment "The bidirectional transport of molecules (cargo) along axonemal microtubules is reduced compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001247 .
obo:CHEBI_15422 a rdfs:Class ;
rdfs:label "ATP" ;
rdfs:comment "An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways." ;
rdfs:subClassOf obo:CHEBI_37045 , obo:CHEBI_37096 .
obo:IAO_0000030 a rdfs:Class ;
rdfs:label "information content entity"@en ;
rdfs:comment "A generically dependent continuant that is about some thing."@en ;
rdfs:subClassOf obo:BFO_0000031 .
obo:IAO_0000136 a rdf:Property ;
rdfs:label "is about"@en ;
rdfs:comment "A (currently) primitive relation that relates an information artifact to an entity."@en ;
rdfs:domain obo:IAO_0000030 ;
rdfs:range .
obo:CHEBI_63248 a rdfs:Class ;
rdfs:label "oxidising agent" ;
rdfs:comment "A substance that removes electrons from another reactant in a redox reaction." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:GO_0098793 a rdfs:Class ;
rdfs:label "presynapse" ;
rdfs:comment "The part of a synapse that is part of the presynaptic cell." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0002038 a rdfs:Class ;
rdfs:label "ciliary localization defective" ;
rdfs:comment "Proteins show defects in their localization in the cilia compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000851 .
obo:GO_0051309 a rdfs:Class ;
rdfs:label "female meiosis chromosome separation" ;
rdfs:comment "The process in which paired chromosomes are physically detached from each other during female meiosis." ;
rdfs:subClassOf obo:GO_0016321 , obo:GO_0051304 , obo:GO_0051307 .
obo:GO_0016079 a rdfs:Class ;
rdfs:label "synaptic vesicle exocytosis" ;
rdfs:comment "Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft." ;
rdfs:subClassOf obo:GO_0045055 , obo:GO_0051649 , obo:GO_0099003 , obo:GO_0099643 .
obo:PATO_0000025 a rdfs:Class ;
rdfs:label "composition" ;
rdfs:comment "A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:WBbt_0005749 a rdfs:Class ;
rdfs:label "coelomic system" ;
rdfs:subClassOf obo:WBbt_0005746 .
obo:GO_0017111 a rdfs:Class ;
rdfs:label "ribonucleoside triphosphate phosphatase activity" ;
rdfs:comment "Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate." ;
rdfs:subClassOf obo:GO_0016462 .
obo:WBPhenotype_0001817 a rdfs:Class ;
rdfs:label "enhanced taste aversion defective" ;
rdfs:comment "The conditioned aversion to a specific chemical compound as a result of that compound being coupled with an unfavorable condition, such as starvation, does not increase to the same extent as observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000147 , obo:WBPhenotype_0001444 .
obo:WBPhenotype_0001190 a rdfs:Class ;
rdfs:label "pharyngeal physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the pharynx to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000606 .
obo:CHEBI_86990 a rdfs:Class ;
rdfs:label "N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ;
rdfs:comment "An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group." ;
rdfs:subClassOf obo:CHEBI_35618 , obo:CHEBI_50995 , obo:CHEBI_83565 .
obo:GO_1905909 a rdfs:Class ;
rdfs:label "regulation of dauer entry" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dauer entry." ;
rdfs:subClassOf obo:GO_0061065 , obo:GO_0065007 .
obo:WBPhenotype_0001420 a rdfs:Class ;
rdfs:label "biofilm absent head" ;
rdfs:comment "Animals can move thorough a lawn of bacterially produced biofilm without accumulating an enormous amount of biofilm on its nose. When C. elegans is exposed to certain bacteria (e.g., Y. pestis), a biofilm accumulates on a worm's head. The presence of this biofilm inhibits feeding by the worm, and thereby prevents growth." ;
rdfs:subClassOf obo:WBPhenotype_0001415 .
obo:GO_0000793 a rdfs:Class ;
rdfs:label "condensed chromosome" ;
rdfs:comment "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure." ;
rdfs:subClassOf obo:GO_0005694 .
obo:GO_0006796 a rdfs:Class ;
rdfs:label "phosphate-containing compound metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." ;
rdfs:subClassOf obo:GO_0006793 .
obo:WBPhenotype_0000103 a rdfs:Class ;
rdfs:label "gut granule development variant" ;
rdfs:comment "Any variation in the progression of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes over time compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000705 .
obo:CHEBI_22698 a rdfs:Class ;
rdfs:label "benzaldehydes" ;
rdfs:comment "Any arenecarbaldehyde that consists of a formyl substituted benzene ring and its substituted derivatives thereof." ;
rdfs:subClassOf obo:CHEBI_33855 .
obo:CHEBI_27369 a rdfs:Class ;
rdfs:label "zwitterion" ;
rdfs:comment "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." ;
rdfs:subClassOf obo:CHEBI_51151 .
obo:CHEBI_23509 a rdfs:Class ;
rdfs:label "cysteine derivative" ;
rdfs:comment "An amino acid derivative resulting from reaction of cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of cysteine by a heteroatom. The definition normally excludes peptides containing cysteine residues." ;
rdfs:subClassOf obo:CHEBI_83821 .
obo:GO_0019777 a rdfs:Class ;
rdfs:label "Atg12 transferase activity" ;
rdfs:comment "Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages." ;
rdfs:subClassOf obo:GO_0019787 .
obo:WBls_0000024 a rdfs:Class ;
rdfs:label "L1 larva Ce" ;
rdfs:comment "The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000106 , obo:WBls_0000818 .
obo:WBPhenotype_0002403 a rdfs:Class ;
rdfs:label "P cell misalignment at ventral midline" ;
rdfs:comment "Ventral midline blastomeres (P cells) are misaligned (not properly paired) along the ventral midline of larval animals." ;
rdfs:subClassOf obo:WBPhenotype_0002402 .
obo:WBPhenotype_0000811 a rdfs:Class ;
rdfs:label "epithelial cell development variant" ;
rdfs:comment "Any variation in the progression of an epithelial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:WBPhenotype_0001955 a rdfs:Class ;
rdfs:label "multiple nuclei oocyte" ;
rdfs:comment "Haploid female germ cells (oocytes) contain more than one nucleus." ;
rdfs:subClassOf obo:WBPhenotype_0000186 , obo:WBPhenotype_0001260 , obo:WBPhenotype_0002413 .
obo:GO_0045666 a rdfs:Class ;
rdfs:label "positive regulation of neuron differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuron differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0045664 , obo:GO_0065007 .
obo:GO_0031143 a rdfs:Class ;
rdfs:label "pseudopodium" ;
rdfs:comment "A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding." ;
rdfs:subClassOf obo:GO_0120025 .
obo:CHEBI_63470 a rdfs:Class ;
rdfs:label "sulfur-containing amino-acid anion" ;
rdfs:comment "A sulfur-containing amino acid whose α-carboxylic acid group is ionized (not protonated)." ;
rdfs:subClassOf obo:CHEBI_37022 .
obo:WBPhenotype_0002463 a rdfs:Class ;
rdfs:label "hookless" ;
rdfs:comment "Male animals lack a copulatory hook." ;
rdfs:subClassOf obo:WBPhenotype_0002209 , obo:WBPhenotype_0002551 .
obo:CHEBI_23849 a rdfs:Class ;
rdfs:label "diterpenoid" ;
rdfs:comment "Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." ;
rdfs:subClassOf obo:CHEBI_26873 .
obo:PATO_0000411 a rdfs:Class ;
rdfs:label "circular" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center." ;
rdfs:subClassOf obo:PATO_0000947 .
obo:CHEBI_46998 a rdfs:Class ;
rdfs:label "ribofuranose" ;
rdfs:comment "A cyclic ribose having a 5-membered tetrahydrofuran ring; the predominant (C3'-endo) form of the two cyclic structures (the other is the \"C2'-endo\" form, having a 6-membered ring) adopted by ribose in aqueous solution." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33942 .
obo:WBPhenotype_0000770 a rdfs:Class ;
rdfs:label "embryonic cell morphology variant" ;
rdfs:comment "Animals exhibit variations in the appearance of embryonic cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002108 .
obo:CHEBI_48356 a rdfs:Class ;
rdfs:label "protic solvent" ;
rdfs:comment "A polar solvent that is capable of acting as a hydron (proton) donor." ;
rdfs:subClassOf obo:CHEBI_39141 , obo:CHEBI_48354 .
obo:CHEBI_25579 a rdfs:Class ;
rdfs:label "nonanone" ;
rdfs:comment "Any ketone that is nonane substituted by an oxo group at unspecified position." ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:WBPhenotype_0000297 a rdfs:Class ;
rdfs:label "rays fused" ;
rdfs:comment "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are joined to one another." ;
rdfs:subClassOf obo:WBPhenotype_0000165 , obo:WBPhenotype_0000199 , obo:WBPhenotype_0000505 .
obo:GO_0045995 a rdfs:Class ;
rdfs:label "regulation of embryonic development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of embryonic development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000026 .
obo:PATO_0000330 a rdfs:Class ;
rdfs:label "irregular spatial pattern" ;
rdfs:comment "A spatial pattern inhering in a bearer by virtue of the bearer's magnitude of or the relationships between its repeated parts lack consistency." ;
rdfs:subClassOf obo:PATO_0000060 .
obo:CHEBI_36347 a rdfs:Class ;
rdfs:label "nuclear particle" ;
rdfs:comment "A nucleus or any of its constituents in any of their energy states." ;
rdfs:subClassOf obo:CHEBI_36342 .
obo:WBPhenotype_0001115 a rdfs:Class ;
rdfs:label "cell cycle timing defective early emb" ;
rdfs:comment "Cell cycle timing is abnormal during the first four cell divisions." ;
rdfs:subClassOf obo:WBPhenotype_0001114 .
obo:GO_0051964 a rdfs:Class ;
rdfs:label "negative regulation of synapse assembly" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ;
rdfs:subClassOf obo:GO_0051961 , obo:GO_0051963 , obo:GO_0065007 , obo:GO_1901889 , obo:GO_1905809 .
obo:GO_0045932 a rdfs:Class ;
rdfs:label "negative regulation of muscle contraction" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." ;
rdfs:subClassOf obo:GO_0006937 , obo:GO_0051241 , obo:GO_0065007 .
obo:GO_0046662 a rdfs:Class ;
rdfs:label "regulation of egg-laying behavior" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium." ;
rdfs:subClassOf obo:GO_0050795 , obo:GO_0065007 , obo:GO_2000241 .
obo:WBPhenotype_0000333 a rdfs:Class ;
rdfs:label "pharyngeal pumps brief" ;
rdfs:comment "The time interval of the stereotyped sequence of muscle contractions by individual pharyngeal muscles that act to draw food into the pharynx is shorter compared to that observed in control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001006 .
obo:WBPhenotype_0004023 a rdfs:Class ;
rdfs:label "frequency of body bend variant" ;
rdfs:comment "Animals exhibit variations in the frequency of oscillations between adjacent body segments from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001703 .
obo:GO_0016462 a rdfs:Class ;
rdfs:label "pyrophosphatase activity" ;
rdfs:comment "Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups." ;
rdfs:subClassOf obo:GO_0016818 .
obo:WBPhenotype_0001041 a rdfs:Class ;
rdfs:label "meiosis defective early emb" ;
rdfs:comment "Animals exhibit defects in the progression of meiosis which ultimately result in embryonic lethality." ;
rdfs:subClassOf obo:WBPhenotype_0000775 , obo:WBPhenotype_0001100 .
obo:WBPhenotype_0002417 a rdfs:Class ;
rdfs:label "spindle rotation variant" ;
rdfs:comment "Any variation in the rotation of the spindle compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002416 .
obo:WBbt_0005738 a rdfs:Class ;
rdfs:label "body region" ;
rdfs:comment "region of the body by which tissues, cells or cell parts are classified" ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:WBPhenotype_0000495 a rdfs:Class ;
rdfs:label "ray ectopic" ;
rdfs:comment "Animals have finger-like sensory sensilla (rays) that are present in places they are normally not found, when compared to the location in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000199 , obo:WBPhenotype_0002498 .
obo:GO_1903035 a rdfs:Class ;
rdfs:label "negative regulation of response to wounding" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding." ;
rdfs:subClassOf obo:GO_0048585 , obo:GO_0065007 , obo:GO_1903034 .
obo:PATO_0001995 a rdfs:Class ;
rdfs:label "organismal quality" ;
rdfs:comment "A quality that inheres in an entire organism or part of an organism." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:WBPhenotype_0001447 a rdfs:Class ;
rdfs:label "ammonium chloride adaptation defective" ;
rdfs:comment "Animals do not exhibit characteristic chemoattractive desensitization to ammonium chloride in a time-concentration dependent and reversible manner compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001444 .
obo:WBPhenotype_0000237 a rdfs:Class ;
rdfs:label "foraging hyperactive" ;
rdfs:comment "Animals extend intensity of roaming and or dwelling activity compared to control animals. In C. elegans, hyperactivity may include an increase in nose-lifts per minute." ;
rdfs:subClassOf obo:WBPhenotype_0000662 .
obo:GO_2000746 a rdfs:Class ;
rdfs:label "regulation of defecation rhythm" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of defecation rhythm." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000292 .
obo:GO_0007165 a rdfs:Class ;
rdfs:label "signal transduction" ;
rdfs:comment "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0050794 .
obo:PATO_0000122 a rdfs:Class ;
rdfs:label "length" ;
rdfs:comment "A 1-D extent quality which is equal to the distance between two points." ;
rdfs:subClassOf obo:PATO_0001708 .
obo:WBbt_0006977 a rdfs:Class ;
rdfs:label "tail ganglion" ;
rdfs:comment "ganglion in the tail region (posterior to rectum)." ;
rdfs:subClassOf obo:WBbt_0005189 .
obo:GO_0040012 a rdfs:Class ;
rdfs:label "regulation of locomotion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:GO_0080090 a rdfs:Class ;
rdfs:label "regulation of primary metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:WBPhenotype_0001515 a rdfs:Class ;
rdfs:label "struts variant" ;
rdfs:comment "Animals exhibit variations in the quantity or patterning of electron-dense columnar structures that join the basal and cortical cuticle layers, from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000948 , obo:WBPhenotype_0002089 .
obo:PATO_0000763 a rdfs:Class ;
rdfs:label "paralysed" ;
rdfs:comment "A behavioral quality inhering in a bearer by virtue of the bearer's being affected by loss of the ability to move a body part." ;
rdfs:subClassOf obo:PATO_0002076 .
obo:CHEBI_5686 a rdfs:Class ;
rdfs:label "heterocyclic compound" ;
rdfs:comment "A cyclic compound having as ring members atoms of at least two different elements." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:WBPhenotype_0001627 a rdfs:Class ;
rdfs:label "locomotion rate serotonin hypersensitive" ;
rdfs:comment "The decrease in locomotion rate in the presence of serotonin is greater than control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000023 , obo:WBPhenotype_0001626 .
obo:WBPhenotype_0000365 a rdfs:Class ;
rdfs:label "embryo osmotic integrity defective early emb" ;
rdfs:comment "Variations in the ability of an embryo to maintain osmotic balance. In C.elegans this can result in an embryo filling the egg shell and lysing." ;
rdfs:subClassOf obo:WBPhenotype_0001178 .
obo:PATO_0000304 a rdfs:Class ;
rdfs:label "decreased speed" ;
rdfs:comment "A speed which is relatively low." ;
rdfs:subClassOf obo:PATO_0000008 , obo:PATO_0002303 .
obo:CHEBI_58025 a rdfs:Class ;
rdfs:label "octopaminium" ;
rdfs:comment "The conjugate acid of octopamine; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:WBPhenotype_0001995 a rdfs:Class ;
rdfs:label "cell cycle progression variant" ;
rdfs:comment "Cells of the animals exhibit variations in the progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000740 .
obo:CHEBI_35444 a rdfs:Class ;
rdfs:label "antinematodal drug" ;
rdfs:comment "A substance used in the treatment or control of nematode infestations." ;
rdfs:subClassOf obo:CHEBI_25491 , obo:CHEBI_35443 .
obo:PATO_0001303 a rdfs:Class ;
rdfs:label "variability" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's disposition to varying or changing." ;
rdfs:subClassOf obo:PATO_0000001 .
obo:WBPhenotype_0001027 a rdfs:Class ;
rdfs:label "nuclear position defective early emb" ;
rdfs:comment "Embryos show defects in the placement of the nucleus to a specific location within the cell." ;
rdfs:subClassOf obo:WBPhenotype_0000511 , obo:WBPhenotype_0001138 .
obo:WBPhenotype_0001227 a rdfs:Class ;
rdfs:label "commissure absent" ;
rdfs:comment "Animals are missing any one of its commissures, an axon tract that connects one body part to another." ;
rdfs:subClassOf obo:WBPhenotype_0001226 .
obo:GO_0009628 a rdfs:Class ;
rdfs:label "response to abiotic stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." ;
rdfs:subClassOf obo:GO_0050896 .
obo:WBPhenotype_0002668 a rdfs:Class ;
rdfs:label "abnormal formation of mitochondrial stress granules (mitoSGs)"@en ;
rdfs:comment "Animals or cells exhibit abnormal formation of mitochondrial stress granules (mitoSGs) compared to controls. mitoSGs are ethidium bromide (EtBr)-staining granules within mitochondria." ;
rdfs:subClassOf obo:WBPhenotype_0002434 .
obo:CHEBI_140601 a rdfs:Class ;
rdfs:label "fatty acid 4:0" ;
rdfs:comment "Any saturated fatty acid containing 4 carbons." ;
rdfs:subClassOf obo:CHEBI_26666 .
obo:WBPhenotype_0002009 a rdfs:Class ;
rdfs:label "proteasome core activity variant" ;
rdfs:comment "Animals exhibit variations from controls in their protein degradation machinery, which functions through the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain." ;
rdfs:subClassOf obo:WBPhenotype_0001644 .
obo:GO_0008284 a rdfs:Class ;
rdfs:label "positive regulation of cell population proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0048522 , obo:GO_0065007 .
obo:WBbt_0005789 a rdfs:Class ;
rdfs:label "pharyngeal segment" ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:WBbt_0005391 a rdfs:Class ;
rdfs:label "amphid sensillum" ;
rdfs:comment "Bilaterally symmetric chemosensory specializations located on the two lateral lips in the head involving a large hole in the anterior cuticle." ;
rdfs:subClassOf obo:WBbt_0006929 .
obo:GO_2000573 a rdfs:Class ;
rdfs:label "positive regulation of DNA biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010557 , obo:GO_0051054 , obo:GO_0065007 , obo:GO_2000278 .
obo:WBPhenotype_0002083 a rdfs:Class ;
rdfs:label "crossover variant" ;
rdfs:comment "The frequency and distribution of crossover events differs from that observed for controls." ;
rdfs:subClassOf obo:WBPhenotype_0002012 .
obo:GO_0007052 a rdfs:Class ;
rdfs:label "mitotic spindle organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0007051 , obo:GO_1902850 .
obo:GO_0140101 a rdfs:Class ;
rdfs:label "catalytic activity, acting on a tRNA" ;
rdfs:comment "Catalytic activity that acts to modify a tRNA." ;
rdfs:subClassOf obo:GO_0140098 .
obo:WBPhenotype_0002498 a rdfs:Class ;
rdfs:label "ectopic organ"@en ;
rdfs:comment "Animals exhibit one or more organs of a particular type in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0000530 , obo:WBPhenotype_0002553 .
obo:GO_2000425 a rdfs:Class ;
rdfs:label "regulation of apoptotic cell clearance" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of apoptotic cell clearance." ;
rdfs:subClassOf obo:GO_0050764 , obo:GO_0065007 .
obo:WBPhenotype_0002336 a rdfs:Class ;
rdfs:label "path curvature increased" ;
rdfs:comment "Animals exhibit increases in the extent to which the overall path of movement is curved, producing tighter and more frequent curves compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002335 .
obo:CHEBI_15740 a rdfs:Class ;
rdfs:label "formate" ;
rdfs:comment "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35757 .
obo:WBPhenotype_0002098 a rdfs:Class ;
rdfs:label "cell component localization variant" ;
rdfs:comment "Any variation in the subcellular localization of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles." ;
rdfs:subClassOf obo:WBPhenotype_0000533 .
obo:WBPhenotype_0000080 a rdfs:Class ;
rdfs:label "no anterior pharynx" ;
rdfs:comment "Animals lack the anterior portion of the pharynx." ;
rdfs:subClassOf obo:WBPhenotype_0000115 , obo:WBPhenotype_0001646 .
obo:WBls_0000035 a rdfs:Class ;
rdfs:label "L3 larva Ce" ;
rdfs:comment "The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch." ;
rdfs:subClassOf obo:WBls_0000108 , obo:WBls_0000820 .
obo:GO_0060756 a rdfs:Class ;
rdfs:label "foraging behavior" ;
rdfs:comment "Behavior by which an organism locates food." ;
rdfs:subClassOf obo:GO_0007610 .
obo:GO_1902883 a rdfs:Class ;
rdfs:label "negative regulation of response to oxidative stress" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress." ;
rdfs:subClassOf obo:GO_0048585 , obo:GO_0065007 , obo:GO_1902882 .
obo:GO_0042660 a rdfs:Class ;
rdfs:label "positive regulation of cell fate specification" ;
rdfs:comment "Any process that activates or enables a cell to adopt a specific fate." ;
rdfs:subClassOf obo:GO_0010455 , obo:GO_0042659 , obo:GO_0065007 .
obo:WBPhenotype_0000510 a rdfs:Class ;
rdfs:label "vulval invagination variant L4" ;
rdfs:comment "The characteristic Christmas-tree shaped invagination formed by the terminal vulval cells at the mid-late L4 stage is altered." ;
rdfs:subClassOf obo:WBPhenotype_0000695 , obo:WBPhenotype_0000699 .
obo:GO_0044840 a rdfs:Class ;
rdfs:label "gut granule" ;
rdfs:comment "A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage." ;
rdfs:subClassOf obo:GO_0031410 .
obo:GO_0016242 a rdfs:Class ;
rdfs:label "negative regulation of macroautophagy" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy." ;
rdfs:subClassOf obo:GO_0010507 , obo:GO_0016241 , obo:GO_0065007 .
obo:WBPhenotype_0001470 a rdfs:Class ;
rdfs:label "diacetyl chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of diacetyl. In C. elegans, at specific concentrations, diacetyl is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001466 .
obo:WBbt_0006909 a rdfs:Class ;
rdfs:label "longitudinal male muscle" ;
rdfs:comment "specialized muscle type in the posterior of adult male." ;
rdfs:subClassOf obo:WBbt_0005757 , obo:WBbt_0005780 , obo:WBbt_0005786 , obo:WBbt_0007810 .
obo:CHEBI_44423 a rdfs:Class ;
rdfs:label "hydroxyurea" ;
rdfs:comment "A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_47857 , obo:CHEBI_64708 .
obo:CHEBI_38323 a rdfs:Class ;
rdfs:label "cholinergic drug" ;
rdfs:comment "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." ;
rdfs:subClassOf obo:CHEBI_35942 .
obo:GO_0019787 a rdfs:Class ;
rdfs:label "ubiquitin-like protein transferase activity" ;
rdfs:comment "Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein." ;
rdfs:subClassOf obo:GO_0016755 , obo:GO_0140096 .
obo:WBPhenotype_0001908 a rdfs:Class ;
rdfs:label "ventral closure defective" ;
rdfs:comment "The animal displays defects in any step of the ventral enclosure process resulting an embryo that is not enclosed and or with interior cells protruding out of the embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001566 .
obo:GO_1900119 a rdfs:Class ;
rdfs:label "positive regulation of execution phase of apoptosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0065007 , obo:GO_1900117 .
obo:CHEBI_24062 a rdfs:Class ;
rdfs:label "fluorine molecular entity" ;
rdfs:subClassOf obo:CHEBI_24471 .
obo:WBPhenotype_0002271 a rdfs:Class ;
rdfs:label "food absorption rate variant" ;
rdfs:comment "Animals exhibit variations in the rate at which food is absorbed by the intestine, as determined by a time-course recording of fat staining (by C1-BODIPY-C12, for example) normalized to controls" ;
rdfs:subClassOf obo:WBPhenotype_0000659 .
obo:GO_0006520 a rdfs:Class ;
rdfs:label "amino acid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups." ;
rdfs:subClassOf obo:GO_0044238 .
obo:GO_0002183 a rdfs:Class ;
rdfs:label "cytoplasmic translational initiation" ;
rdfs:comment "The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." ;
rdfs:subClassOf obo:GO_0006413 .
obo:GO_1904860 a rdfs:Class ;
rdfs:label "DNA synthesis involved in mitotic DNA replication" ;
rdfs:comment "Any DNA biosynthetic process that is involved in mitotic DNA replication." ;
rdfs:subClassOf obo:GO_0071897 , obo:GO_0090592 , obo:GO_1903047 .
obo:WBPhenotype_0002292 a rdfs:Class ;
rdfs:label "body posture amplitude decreased" ;
rdfs:comment "Animals exhibit variations in body posture caused by a decrease in the extent of displacement measured from the mean position to an extreme position compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002291 .
obo:WBbt_0008289 a rdfs:Class ;
rdfs:label "vulval syncytia precursor" ;
rdfs:comment "precursor cell of, before fusion to form vulval syncytia vulA(4), vulC(4), vulD(2), vulE(4) and vulF(4)." ;
rdfs:subClassOf obo:WBbt_0008073 .
obo:GO_0061642 a rdfs:Class ;
rdfs:label "chemoattraction of axon" ;
rdfs:comment "The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal." ;
rdfs:subClassOf obo:GO_0050918 .
obo:WBbt_0005189 a rdfs:Class ;
rdfs:label "ganglion" ;
rdfs:comment "A cluster of nerve cells and associated glial cells (nuclear location)." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:WBPhenotype_0000883 a rdfs:Class ;
rdfs:label "nerve ring development variant" ;
rdfs:comment "Variations in the progression of the major zone of overlapping axons in the head, which encircles the isthmus of the pharynx to form a tightly packed ring-like structure on the outside of the pharynx, over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000945 .
obo:WBPhenotype_0002599 a rdfs:Class ;
rdfs:label "long-term habituation phenotype"@en ;
rdfs:comment "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s)." ;
rdfs:subClassOf obo:WBPhenotype_0000626 .
obo:GO_0051338 a rdfs:Class ;
rdfs:label "regulation of transferase activity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." ;
rdfs:subClassOf obo:GO_0050790 , obo:GO_0065007 .
obo:GO_0051707 a rdfs:Class ;
rdfs:label "response to other organism" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." ;
rdfs:subClassOf obo:GO_0043207 , obo:GO_0044419 .
obo:WBPhenotype_0000907 a rdfs:Class ;
rdfs:label "anus morphology variant" ;
rdfs:comment "Any variation in the structural appearance of the caudal opening of the rectum in the tail compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000598 , obo:WBPhenotype_0002558 .
obo:WBPhenotype_0000671 a rdfs:Class ;
rdfs:label "resistant to copper" ;
rdfs:comment "Animals fail to respond to the concentration of copper that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to copper to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000592 , obo:WBPhenotype_0001502 .
obo:GO_0072664 a rdfs:Class ;
rdfs:label "maintenance of protein location in peroxisome" ;
rdfs:comment "Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0072595 .
obo:WBPhenotype_0001897 a rdfs:Class ;
rdfs:label "light response variant" ;
rdfs:comment "Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus (electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:CHEBI_61692 a rdfs:Class ;
rdfs:label "pyridoisoquinoline" ;
rdfs:comment "An organic heterotricyclic compound with a skeleton derived from a pyridine ring fused to an isoquinoline." ;
rdfs:subClassOf obo:CHEBI_26979 .
obo:CHEBI_23117 a rdfs:Class ;
rdfs:label "chlorine molecular entity" ;
rdfs:comment "A halogen molecular entity containing one or more atoms of chlorine." ;
rdfs:subClassOf obo:CHEBI_24471 .
obo:GO_0010817 a rdfs:Class ;
rdfs:label "regulation of hormone levels" ;
rdfs:comment "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." ;
rdfs:subClassOf obo:GO_0065008 .
obo:WBPhenotype_0001673 a rdfs:Class ;
rdfs:label "telomere homeostasis variant" ;
rdfs:comment "Animals exhibit variations in the processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA, which allow the chromosome to persist from generation to generation, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000585 .
obo:WBPhenotype_0001526 a rdfs:Class ;
rdfs:label "ciliated neuron morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of any one of the specialized sensory receptor cells of the nervous system that compared to control animals. In C. elegans, these specialized cells are characterized as having axoneme containing dendritic projections emanating from their cell body." ;
rdfs:subClassOf obo:WBPhenotype_0000299 , obo:WBPhenotype_0000905 .
obo:WBls_0000804 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring post embryogenesis"@en ;
rdfs:comment "A C. elegans life stage that occurs after embryogenesis" ;
rdfs:subClassOf obo:WBls_0000825 .
obo:CHEBI_33242 a rdfs:Class ;
rdfs:label "inorganic hydride" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_33692 .
obo:GO_0006886 a rdfs:Class ;
rdfs:label "intracellular protein transport" ;
rdfs:comment "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." ;
rdfs:subClassOf obo:GO_0015031 , obo:GO_0046907 .
obo:CHEBI_59724 a rdfs:Class ;
rdfs:label "ribonucleoside triphosphate oxoanion" ;
rdfs:comment "An organophosphate anion resulting from deprotonation of at least one of the acidic hydroxy groups from the triphosphate moiety of a nucleoside triphosphate." ;
rdfs:subClassOf obo:CHEBI_58945 .
obo:GO_0045055 a rdfs:Class ;
rdfs:label "regulated exocytosis" ;
rdfs:comment "A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand." ;
rdfs:subClassOf obo:GO_0006887 .
obo:WBPhenotype_0000196 a rdfs:Class ;
rdfs:label "distal tip cell morphology variant" ;
rdfs:comment "The morphological appearance of distal tip cells is varied compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002108 .
obo:WBPhenotype_0001092 a rdfs:Class ;
rdfs:label "larval defecation defect" ;
rdfs:comment "Animals fail to expel fecal matter during the larval stage." ;
rdfs:subClassOf obo:WBPhenotype_0001091 .
obo:GO_0046890 a rdfs:Class ;
rdfs:label "regulation of lipid biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0019216 , obo:GO_0065007 .
obo:WBPhenotype_0001075 a rdfs:Class ;
rdfs:label "vulval muscle physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the vulva muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000613 , obo:WBPhenotype_0000929 , obo:WBPhenotype_0000990 .
obo:GO_2001235 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic signaling pathway" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway." ;
rdfs:subClassOf obo:GO_0009967 , obo:GO_0043065 , obo:GO_0065007 , obo:GO_2001233 .
obo:CHEBI_23677 a rdfs:Class ;
rdfs:label "diazole" ;
rdfs:comment "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." ;
rdfs:subClassOf obo:CHEBI_68452 .
obo:CHEBI_76668 a rdfs:Class ;
rdfs:label "EC 2.7.* (P-containing group transferase) inhibitor" ;
rdfs:comment "A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*)." ;
rdfs:subClassOf obo:CHEBI_71300 .
obo:WBPhenotype_0001035 a rdfs:Class ;
rdfs:label "nuclear appearance number defective early emb" ;
rdfs:comment "The size, number and organization of the components of the nuclei in the early embryo deviate from control . In C. elegans, this is characterized by nuclei that are completely missing or are significantly smaller than normal; often accompanied by spindle and cytokinesis defects." ;
rdfs:subClassOf obo:WBPhenotype_0000770 , obo:WBPhenotype_0001138 .
obo:WBPhenotype_0000962 a rdfs:Class ;
rdfs:label "level of transgene expression variant" ;
rdfs:comment "Any variation in the measured expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000306 , obo:WBPhenotype_0002575 .
obo:GO_0045920 a rdfs:Class ;
rdfs:label "negative regulation of exocytosis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." ;
rdfs:subClassOf obo:GO_0017157 , obo:GO_0065007 , obo:GO_1903531 .
obo:WBPhenotype_0000338 a rdfs:Class ;
rdfs:label "tail swelling" ;
rdfs:comment "Swelling in the post anal region compared to control. In C. elegans this swelling can be associated with infection from the nematode-specific bacterial pathogen, Microbacterium nematophilum." ;
rdfs:subClassOf obo:WBPhenotype_0000073 .
obo:WBPhenotype_0002482 a rdfs:Class ;
rdfs:label "heme levels increased" ;
rdfs:comment "Animals exhibit an increase in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring." ;
rdfs:subClassOf obo:WBPhenotype_0002480 .
obo:GO_0042645 a rdfs:Class ;
rdfs:label "mitochondrial nucleoid" ;
rdfs:comment "The region of a mitochondrion to which the DNA is confined." ;
rdfs:subClassOf obo:GO_0009295 , obo:GO_0043232 .
obo:WBPhenotype_0000077 a rdfs:Class ;
rdfs:label "cuticle shedding defect" ;
rdfs:comment "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement." ;
rdfs:subClassOf obo:WBPhenotype_0000638 .
obo:PATO_0001798 a rdfs:Class ;
rdfs:label "kinked" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the bearer's having multiple angles in its length." ;
rdfs:subClassOf obo:PATO_0000617 .
obo:GO_0031110 a rdfs:Class ;
rdfs:label "regulation of microtubule polymerization or depolymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070507 .
obo:GO_0002164 a rdfs:Class ;
rdfs:label "larval development" ;
rdfs:comment "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." ;
rdfs:subClassOf obo:GO_0007275 , obo:GO_0009791 .
obo:GO_0032239 a rdfs:Class ;
rdfs:label "regulation of nucleobase-containing compound transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:CHEBI_35620 a rdfs:Class ;
rdfs:label "vasodilator agent" ;
rdfs:comment "A drug used to cause dilation of the blood vessels." ;
rdfs:subClassOf obo:CHEBI_35554 .
obo:GO_0005643 a rdfs:Class ;
rdfs:label "nuclear pore" ;
rdfs:comment "A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined." ;
rdfs:subClassOf obo:GO_0140513 .
obo:CHEBI_37957 a rdfs:Class ;
rdfs:label "histaminergic drug" ;
rdfs:comment "Drugs used for their actions on histaminergic systems." ;
rdfs:subClassOf obo:CHEBI_35942 .
obo:GO_0106030 a rdfs:Class ;
rdfs:label "neuron projection fasciculation" ;
rdfs:comment "The collection of neuronal projections into a bundle of rods, known as a fascicle." ;
rdfs:subClassOf obo:GO_0031175 .
obo:GO_0098798 a rdfs:Class ;
rdfs:label "mitochondrial protein-containing complex" ;
rdfs:comment "A protein complex that is part of a mitochondrion." ;
rdfs:subClassOf obo:GO_0032991 .
obo:GO_0099517 a rdfs:Class ;
rdfs:label "synaptic vesicle transport along microtubule" ;
rdfs:comment "The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors." ;
rdfs:subClassOf obo:GO_0047496 , obo:GO_0099514 .
obo:GO_0032094 a rdfs:Class ;
rdfs:label "response to food" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat." ;
rdfs:subClassOf obo:GO_0031667 , obo:GO_0042221 .
obo:CHEBI_26959 a rdfs:Class ;
rdfs:label "thiocarboxylic ester" ;
rdfs:comment "An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur." ;
rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_35701 .
obo:WBPhenotype_0001612 a rdfs:Class ;
rdfs:label "ethanol resistant" ;
rdfs:comment "Animals fail to respond to the concentration of ethanol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to ethanol to elicit the response compared to control animals. In C.elegans the phenotype designation Jud is short for JUDang, which is Korean for resistant to alcohol." ;
rdfs:subClassOf obo:WBPhenotype_0000009 , obo:WBPhenotype_0001502 .
obo:GO_0030163 a rdfs:Class ;
rdfs:label "protein catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ;
rdfs:subClassOf obo:GO_0009057 , obo:GO_0019538 .
obo:WBPhenotype_0002049 a rdfs:Class ;
rdfs:label "abamectin repsonse variant" ;
rdfs:comment "Animals are not affected to the same degree as control animals under similar conditions of abamectin exposure." ;
rdfs:subClassOf obo:WBPhenotype_0000631 , obo:WBPhenotype_0001852 .
obo:WBPhenotype_0002588 a rdfs:Class ;
rdfs:label "basement membrane phenotype"@en ;
rdfs:comment "Animals exhibit variations or abnormalities in the structure, integrity, function, or quality of basement membranes, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001210 .
obo:GO_0051232 a rdfs:Class ;
rdfs:label "meiotic spindle elongation" ;
rdfs:comment "The lengthening of the distance between poles of the spindle during a meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0051231 , obo:GO_1903046 .
obo:WBbt_0005792 a rdfs:Class ;
rdfs:label "intestinal cell" ;
rdfs:comment "any of 20 large epithelial cells which form a tube and are mostly situated as bilaterally symmetric pairs around the tubular lumen. Each of these cell pairs forms an intestinal ring ( II-IX int rings). The most anterior intestinal ring (int ring I), however, is made of four cells. Intestinal cells contain large nuclei with large nucleoli and numerous autofluorescent granules in their cytoplasm." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_1903305 a rdfs:Class ;
rdfs:label "regulation of regulated secretory pathway" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of regulated secretory pathway." ;
rdfs:subClassOf obo:GO_0017157 , obo:GO_0065007 .
obo:WBPhenotype_0000292 a rdfs:Class ;
rdfs:label "organ system pigmentation phenotype" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a organ system." ;
rdfs:subClassOf obo:WBPhenotype_0000521 , obo:WBPhenotype_0000534 .
obo:GO_0048841 a rdfs:Class ;
rdfs:label "regulation of axon extension involved in axon guidance" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance." ;
rdfs:subClassOf obo:GO_0030516 , obo:GO_0065007 .
obo:WBPhenotype_0000310 a rdfs:Class ;
rdfs:label "cilia absent" ;
rdfs:comment "Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000615 .
obo:GO_0034242 a rdfs:Class ;
rdfs:label "negative regulation of syncytium formation by plasma membrane fusion" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0060142 , obo:GO_0065007 .
obo:WBPhenotype_0000118 a rdfs:Class ;
rdfs:label "L2 lethal" ;
rdfs:comment "L2 lethal: Animals die at the L2 stage of the life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000057 , obo:WBPhenotype_0000116 .
obo:PATO_0001444 a rdfs:Class ;
rdfs:label "broken" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer's components no longer being in a single contiguous unit." ;
rdfs:subClassOf obo:PATO_0001442 .
obo:CHEBI_73693 a rdfs:Class ;
rdfs:label "ketone body" ;
rdfs:comment "A carbonyl compound produced as a water-soluble byproduct when fatty acids are broken down for energy in the liver. There are three endogenous ketone bodies: acetone, acetoacetic acid, and (R)-3-hydroxybutyric acid; others may be produced as a result of the metabolism of synthetic triglycerides." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_36586 , obo:CHEBI_61697 .
obo:CHEBI_38870 a rdfs:Class ;
rdfs:label "inhalation anaesthetic" ;
rdfs:subClassOf obo:CHEBI_38869 .
obo:WBPhenotype_0001571 a rdfs:Class ;
rdfs:label "body wall muscle cell polarization variant" ;
rdfs:comment "Variations in the accumulation of muscle proteins at membranes where adjacent muscle cells contact each other and the hypodermis compared to control. In C. elegans, during early embryonic body wall muscle development, muscle, basement membrane, and hypodermal components are all colocalized in a continuous linear structure at the site of muscle-hypodermal contact." ;
rdfs:subClassOf obo:WBPhenotype_0000926 .
obo:WBPhenotype_0001018 a rdfs:Class ;
rdfs:label "cytokinesis variant emb" ;
rdfs:comment "Any variation that disrupts the cytoplasmic division of a cell during embryonic development compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000050 , obo:WBPhenotype_0002408 .
obo:WBPhenotype_0000995 a rdfs:Class ;
rdfs:comment "OBSOLETE." .
obo:GO_0010720 a rdfs:Class ;
rdfs:label "positive regulation of cell development" ;
rdfs:comment "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0060284 , obo:GO_0065007 .
obo:PATO_0001633 a rdfs:Class ;
rdfs:label "posterior to" ;
rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's being located toward the rear of an organism relative to another entity." ;
rdfs:subClassOf obo:PATO_0000140 .
obo:GO_0005788 a rdfs:Class ;
rdfs:label "endoplasmic reticulum lumen" ;
rdfs:comment "The volume enclosed by the membranes of the endoplasmic reticulum." ;
rdfs:subClassOf obo:GO_0031974 , obo:GO_0070013 .
obo:GO_0140237 a rdfs:Class ;
rdfs:label "translation at presynapse, modulating chemical synaptic transmission" ;
rdfs:comment "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission." ;
rdfs:subClassOf obo:GO_0006412 , obo:GO_0140236 .
obo:CHEBI_37733 a rdfs:Class ;
rdfs:label "EC 3.1.1.8 (cholinesterase) inhibitor" ;
rdfs:comment "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8)." ;
rdfs:subClassOf obo:CHEBI_76773 .
obo:WBPhenotype_0000876 a rdfs:Class ;
rdfs:label "organism osmotic stress response variant" ;
rdfs:comment "Animals exhibit variations in their response to osmotic stress compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBls_0000809 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during bean embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the bean embryo life stage" ;
rdfs:subClassOf obo:WBls_0000805 .
obo:PATO_0000460 a rdfs:Class ;
rdfs:label "abnormal" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's deviation from normal or average." ;
rdfs:subClassOf obo:PATO_0000069 .
obo:CHEBI_28938 a rdfs:Class ;
rdfs:label "ammonium" ;
rdfs:comment "An onium cation obtained by protonation of ammonia." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35106 , obo:CHEBI_50313 , obo:CHEBI_60242 .
obo:CHEBI_33432 a rdfs:Class ;
rdfs:label "monoatomic chlorine" ;
rdfs:subClassOf obo:CHEBI_33431 , obo:CHEBI_33433 .
obo:GO_0045773 a rdfs:Class ;
rdfs:label "positive regulation of axon extension" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of axon extension." ;
rdfs:subClassOf obo:GO_0030307 , obo:GO_0030516 , obo:GO_0048639 , obo:GO_0050772 , obo:GO_0065007 .
obo:WBPhenotype_0002432 a rdfs:Class ;
rdfs:label "EGF-induced sleep variant" ;
rdfs:comment "Animals do not respond with sleeping behavior induced through the EGF pathway. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals." ;
rdfs:subClassOf obo:WBPhenotype_0001524 .
obo:CHEBI_35589 a rdfs:Class ;
rdfs:label "9H-purine" ;
rdfs:comment "The 9H-tautomer of purine." ;
rdfs:subClassOf obo:CHEBI_35584 .
obo:WBPhenotype_0001684 a rdfs:Class ;
rdfs:label "synaptic vesicle homeostasis variant" ;
rdfs:comment "The rates of synaptic vesicle exocytosis and endocytosis vary from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000846 .
obo:WBPhenotype_0001739 a rdfs:Class ;
rdfs:label "aging variant" ;
rdfs:comment "Any variation in an organism's decline over time from its optimal fertility and viability compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000576 .
obo:WBPhenotype_0002516 a rdfs:Class ;
rdfs:label "burrowing assay distance abnormal"@en ;
rdfs:comment "Animals exhibit variations, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Variations in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect variations in neuromuscular efficacy of locomotion." ;
rdfs:subClassOf obo:WBPhenotype_0002559 .
obo:GO_0030517 a rdfs:Class ;
rdfs:label "negative regulation of axon extension" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth." ;
rdfs:subClassOf obo:GO_0030308 , obo:GO_0030516 , obo:GO_0048640 , obo:GO_0050771 , obo:GO_0065007 .
obo:CHEBI_38147 a rdfs:Class ;
rdfs:label "cardiotonic drug" ;
rdfs:comment "A drug that has a strengthening effect on the heart or that can increase cardiac output." ;
rdfs:subClassOf obo:CHEBI_35554 .
obo:CHEBI_25900 a rdfs:Class ;
rdfs:label "aldopentose phosphate" ;
rdfs:subClassOf obo:CHEBI_35131 , obo:CHEBI_84055 .
obo:PATO_0002264 a rdfs:Class ;
rdfs:label "organization quality" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer's being arranged in a systematic fashion." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:WBPhenotype_0001086 a rdfs:Class ;
rdfs:label "trimethylthiazole chemotaxis defective" ;
rdfs:comment "Failure to execute characteristic response to trimethylthiazole compared to control. In C. elegans, animals move towards typically attractive concentrations of trimethylthiazole." ;
rdfs:subClassOf obo:WBPhenotype_0001438 , obo:WBPhenotype_0001475 .
obo:CHEBI_76848 a rdfs:Class ;
rdfs:label "EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor" ;
rdfs:comment "An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*)." ;
rdfs:subClassOf obo:CHEBI_76744 .
obo:WBPhenotype_0001210 a rdfs:Class ;
rdfs:label "pericellular component physiology phenotype" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process taking place in extracellular spaces within or associated with the organism, from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000519 .
obo:PATO_0001767 a rdfs:Class ;
rdfs:label "semi-fertile" ;
rdfs:subClassOf obo:PATO_0000274 .
obo:WBPhenotype_0001779 a rdfs:Class ;
rdfs:label "miRNA expression variant" ;
rdfs:comment "Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:GO_0007127 a rdfs:Class ;
rdfs:label "meiosis I" ;
rdfs:comment "The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei." ;
rdfs:subClassOf obo:GO_0061982 , obo:GO_0140013 .
obo:CHEBI_35481 a rdfs:Class ;
rdfs:label "non-narcotic analgesic" ;
rdfs:comment "A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors." ;
rdfs:subClassOf obo:CHEBI_35480 .
obo:GO_0032459 a rdfs:Class ;
rdfs:label "regulation of protein oligomerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein oligomerization." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0065007 .
obo:WBPhenotype_0002323 a rdfs:Class ;
rdfs:label "backward point velocity variant" ;
rdfs:comment "Animals exhibit variations in the velocity of backward translocation of any point along the animal's track from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0004025 .
obo:WBbt_0005828 a rdfs:Class ;
rdfs:label "gonadal sheath cell" ;
rdfs:comment "five pairs of thin gonadal sheath cells form a single layer covering the germ line component of each arm, each pair occupying a stereotyped position along the gonad proximal-distal axis." ;
rdfs:subClassOf obo:WBbt_0005781 , obo:WBbt_0005786 , obo:WBbt_0007815 .
obo:CHEBI_50904 a rdfs:Class ;
rdfs:label "allergen" ;
rdfs:comment "A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:WBPhenotype_0002518 a rdfs:Class ;
rdfs:label "axon length abnormal"@en ;
rdfs:comment "The length of one or more axons is abnormal compared to the length of the corresponding axon(s) in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000180 .
obo:WBPhenotype_0001966 a rdfs:Class ;
rdfs:label "cell endomembrane physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of within the cell, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001965 .
obo:WBPhenotype_0001126 a rdfs:Class ;
rdfs:label "cell cell contacts abnormal in four cell embryo" ;
rdfs:comment "Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos." ;
rdfs:subClassOf obo:WBPhenotype_0001117 .
obo:WBPhenotype_0001142 a rdfs:Class ;
rdfs:label "nuclear number defective early emb" ;
rdfs:comment "Nuclear number is abnormal in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001035 , obo:WBPhenotype_0001894 .
obo:CHEBI_36915 a rdfs:Class ;
rdfs:label "inorganic cation" ;
rdfs:subClassOf obo:CHEBI_36914 , obo:CHEBI_36916 .
obo:WBPhenotype_0001690 a rdfs:Class ;
rdfs:label "constitutive larval display" ;
rdfs:comment "Animals display surface antigens throughout all larval stages, unlike Bristol N2 worms, which display the antigens only during one larval stage." ;
rdfs:subClassOf obo:WBPhenotype_0001677 .
obo:CHEBI_36862 a rdfs:Class ;
rdfs:label "14beta-hydroxy steroid" ;
rdfs:comment "A 14-hydroxy steroid in which the hydroxy group has a β-configuration." ;
rdfs:subClassOf obo:CHEBI_36860 .
obo:WBPhenotype_0001339 a rdfs:Class ;
rdfs:label "egg laying levamisole resistant" ;
rdfs:comment "Animals are not induced to lay eggs in reponse to exogenous levamisole. In C. elegans, levamisole stimulates egg-laying." ;
rdfs:subClassOf obo:WBPhenotype_0000421 , obo:WBPhenotype_0001101 .
obo:CHEBI_78675 a rdfs:Class ;
rdfs:label "fundamental metabolite" ;
rdfs:comment "Any metabolite produced by all living cells." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:WBPhenotype_0001046 a rdfs:Class ;
rdfs:label "pharyngeal muscle morphology variant" ;
rdfs:comment "Any variations associated with the characteristic morphology of the pharyngeal muscle such as shape, birefringence etc compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000923 .
obo:WBPhenotype_0002260 a rdfs:Class ;
rdfs:label "gamete necrotic death increased" ;
rdfs:comment "Ooctyes and or sperm appear vacuolated and degenerated compared to gametes in control animals. This degeneration is not due to normal programmed cell death." ;
rdfs:subClassOf obo:WBPhenotype_0001397 .
obo:GO_0008584 a rdfs:Class ;
rdfs:label "male gonad development" ;
rdfs:comment "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0008406 .
obo:WBPhenotype_0001261 a rdfs:Class ;
rdfs:label "pale" ;
rdfs:comment "Animals show deficiencies in chroma resulting in increased translucency." ;
rdfs:subClassOf obo:WBPhenotype_0000527 .
obo:WBPhenotype_0001936 a rdfs:Class ;
rdfs:label "resistant to protein aggregation induced paralysis" ;
rdfs:comment "Animals fail to respond to the aggregation of proteins that elicits a paralysis response in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001935 .
obo:WBPhenotype_0000221 a rdfs:Class ;
rdfs:label "neurotransmitter metabolism variant" ;
rdfs:comment "Animals exhibit variations in any chemical reaction or pathway involving neurotransmitters compared to control animals. Neurotransmitters are any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0000827 a rdfs:Class ;
rdfs:label "V lineages variant" ;
rdfs:comment "The descendants of any of the V precursor cells (V1-V6) exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000825 .
obo:GO_1900407 a rdfs:Class ;
rdfs:label "regulation of cellular response to oxidative stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cellular response to oxidative stress." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080135 , obo:GO_1902882 .
obo:GO_1903036 a rdfs:Class ;
rdfs:label "positive regulation of response to wounding" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of response to wounding." ;
rdfs:subClassOf obo:GO_0048584 , obo:GO_0065007 , obo:GO_1903034 .
obo:GO_0010892 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial translation in response to stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0032056 , obo:GO_0065007 , obo:GO_0070131 .
obo:WBPhenotype_0000871 a rdfs:Class ;
rdfs:label "obsolete connected mitochondria epithelial" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000480 a rdfs:Class ;
rdfs:label "pyrazine chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to pyrazine as defined by control animals. In C. elegans pyrazine is typically an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001438 , obo:WBPhenotype_0001474 .
obo:WBPhenotype_0002285 a rdfs:Class ;
rdfs:label "head bend angle decreased" ;
rdfs:comment "Animals exhibit a decrease in the extent of the maximum flex of the most anterior portion of the animal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002284 .
obo:GO_0045933 a rdfs:Class ;
rdfs:label "positive regulation of muscle contraction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of muscle contraction." ;
rdfs:subClassOf obo:GO_0006937 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0032222 a rdfs:Class ;
rdfs:label "regulation of synaptic transmission, cholinergic" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 .
obo:WBPhenotype_0001533 a rdfs:Class ;
rdfs:label "outer labial morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum." ;
rdfs:subClassOf obo:WBPhenotype_0001531 .
obo:WBPhenotype_0001865 a rdfs:Class ;
rdfs:label "protein ubiquitination variant" ;
rdfs:comment "Variations in the process by which one or more ubiquitin moieties are added to a protein, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001382 .
obo:WBPhenotype_0000687 a rdfs:Class ;
rdfs:label "feminization of XX and XO animals" ;
rdfs:comment "Both hermaphrodites and males develop into fertile females." ;
rdfs:subClassOf obo:WBPhenotype_0000049 , obo:WBPhenotype_0000624 , obo:WBPhenotype_0000822 .
obo:WBPhenotype_0001988 a rdfs:Class ;
rdfs:label "detergent hypersensitive" ;
rdfs:comment "Animals respond to a detergent at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001918 .
obo:PATO_0001603 a rdfs:Class ;
rdfs:label "increased life span" ;
rdfs:comment "A life span which is relatively high." ;
rdfs:subClassOf obo:PATO_0000050 , obo:PATO_0002305 .
obo:WBPhenotype_0001713 a rdfs:Class ;
rdfs:label "locomotory rhythm variant" ;
rdfs:comment "Animals exhibit variations in locomotor activity during its light/dark cycle from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001711 .
obo:CHEBI_39217 a rdfs:Class ;
rdfs:label "antibiotic nematicide" ;
rdfs:subClassOf obo:CHEBI_25491 , obo:CHEBI_39215 .
obo:WBPhenotype_0002550 a rdfs:Class ;
rdfs:label "conflicted kinker with gradual backward movement"@en ;
rdfs:comment "Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves, and over time has a tendency to move slowly backward due to a dominating reversal neural circuit." ;
rdfs:subClassOf obo:WBPhenotype_0002548 .
obo:CHEBI_23493 a rdfs:Class ;
rdfs:label "cyclopentanes" ;
rdfs:comment "Cyclopentane and its derivatives formed by substitution." ;
rdfs:subClassOf obo:CHEBI_33598 .
obo:WBPhenotype_0000911 a rdfs:Class ;
rdfs:label "coelomocyte morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of coelomocytes compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000533 , obo:WBPhenotype_0000599 .
obo:CHEBI_25000 a rdfs:Class ;
rdfs:label "lactone" ;
rdfs:comment "Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." ;
rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_38104 .
obo:GO_0042402 a rdfs:Class ;
rdfs:label "biogenic amine catabolic process" ;
rdfs:comment "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ;
rdfs:subClassOf obo:GO_0009310 .
obo:WBPhenotype_0002393 a rdfs:Class ;
rdfs:label "anterior posterior neurite growth variant" ;
rdfs:comment "Any variation in the processes that govern the directed extension of neurite projections along the anteroposterior axis of the animal compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000572 .
obo:CHEBI_33245 a rdfs:Class ;
rdfs:label "organic fundamental parent" ;
rdfs:comment "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." ;
rdfs:subClassOf obo:CHEBI_37175 , obo:CHEBI_50860 .
obo:GO_1903490 a rdfs:Class ;
rdfs:label "positive regulation of mitotic cytokinesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis." ;
rdfs:subClassOf obo:GO_0032467 , obo:GO_0065007 , obo:GO_1902412 .
obo:WBPhenotype_0001395 a rdfs:Class ;
rdfs:label "body vacuole" ;
rdfs:comment "Vacuoles accumulate in the body. A vacuole is a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material." ;
rdfs:subClassOf obo:WBPhenotype_0000072 , obo:WBPhenotype_0002615 .
obo:GO_0010453 a rdfs:Class ;
rdfs:label "regulation of cell fate commitment" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0050794 , obo:GO_0065007 .
obo:CHEBI_24922 a rdfs:Class ;
rdfs:label "isoquinolines" ;
rdfs:comment "A class of organic heteropolycyclic compound consisting of isoquinoline and its substitution derivatives." ;
rdfs:subClassOf obo:CHEBI_38101 , obo:CHEBI_38166 .
obo:WBbt_0005374 a rdfs:Class ;
rdfs:label "anterior gonad arm" ;
rdfs:comment "Anterior lobe of the bi-lobbed hermaphrodite gonad." ;
rdfs:subClassOf obo:WBbt_0008629 .
obo:CHEBI_17568 a rdfs:Class ;
rdfs:label "uracil" ;
rdfs:comment "A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_26432 , obo:CHEBI_38337 .
obo:CHEBI_26292 a rdfs:Class ;
rdfs:label "propanones" ;
rdfs:comment "A ketone that is propane carrying at least one oxo substituent." ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:WBPhenotype_0000366 a rdfs:Class ;
rdfs:label "three fold arrest" ;
rdfs:comment "Cessation of development that normally occurs in C. elegans 520-620min after the first cleavage at 20C, the stage between the 2-fold and fully elongated embryo." ;
rdfs:subClassOf obo:WBPhenotype_0000779 .
obo:GO_0000077 a rdfs:Class ;
rdfs:label "DNA damage checkpoint signaling" ;
rdfs:comment "A signal transduction process that contributes to a DNA damage checkpoint." ;
rdfs:subClassOf obo:GO_0031570 , obo:GO_0042770 .
obo:WBPhenotype_0002519 a rdfs:Class ;
rdfs:label "axon length reduced"@en ;
rdfs:comment "The length of one or more axons is reduced compared to the length of the corresponding axon(s) in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002518 .
obo:WBls_0000057 a rdfs:Class ;
rdfs:label "adult hermaphrodite Ce" ;
rdfs:comment "The stage after an hermaphrodite animal is fully-developed and reaches maturity." ;
rdfs:subClassOf obo:WBls_0000041 .
obo:GO_0006479 a rdfs:Class ;
rdfs:label "protein methylation" ;
rdfs:comment "The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom." ;
rdfs:subClassOf obo:GO_0008213 , obo:GO_0043414 .
obo:WBPhenotype_0000900 a rdfs:Class ;
rdfs:label "germ cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of germ cells compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002108 .
obo:GO_0006885 a rdfs:Class ;
rdfs:label "regulation of pH" ;
rdfs:comment "Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell." ;
rdfs:subClassOf obo:GO_0055080 , obo:GO_0065007 .
obo:WBPhenotype_0002340 a rdfs:Class ;
rdfs:label "body proportion decreased" ;
rdfs:comment "Animals exhibit decreases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002338 .
obo:WBPhenotype_0000055 a rdfs:Class ;
rdfs:label "early larval arrest" ;
rdfs:comment "Larvae arrest during early larval development. In C. elegans, this occurs during the L1 or L2 stages of larval development." ;
rdfs:subClassOf obo:WBPhenotype_0000059 .
obo:WBPhenotype_0000427 a rdfs:Class ;
rdfs:label "no cuticle" ;
rdfs:comment "Animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000201 , obo:WBPhenotype_0002558 .
obo:CHEBI_33296 a rdfs:Class ;
rdfs:label "alkali metal molecular entity" ;
rdfs:comment "A molecular entity containing one or more atoms of an alkali metal." ;
rdfs:subClassOf obo:CHEBI_33674 .
obo:GO_1902806 a rdfs:Class ;
rdfs:label "regulation of cell cycle G1/S phase transition" ;
rdfs:comment "Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901987 .
obo:WBPhenotype_0002428 a rdfs:Class ;
rdfs:label "intestinal degeneration" ;
rdfs:comment "Animals exhibit degeneration of the intestine, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000710 .
obo:WBbt_0005767 a rdfs:Class ;
rdfs:label "pharyngeal-intestinal valve" ;
rdfs:comment "A group of six equivalent cells forms a tightly constructed 'valve' that links the posterior bulb of the pharynx to the anterior four cells of the intestine. These six cells comprise a small epithelial channel with a cuticular lining in continuity with the pharyngeal cuticle and link the lumen of the pharynx to the large lumen of the anterior intestine." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:BFO_0000001 a rdfs:Class ;
rdfs:label "entity"@en .
obo:CL_0001061 a rdfs:Class ;
rdfs:label "abnormal cell" ;
rdfs:comment "A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models." ;
rdfs:subClassOf obo:CL_0000000 .
obo:WBPhenotype_0000269 a rdfs:Class ;
rdfs:label "obsolete unclassified" ;
rdfs:comment "OBSOLETE. Animals display a phenotype that has not yet been assigned to a current classification." .
obo:CHEBI_33860 a rdfs:Class ;
rdfs:label "aromatic amine" ;
rdfs:comment "An amino compound in which the amino group is linked directly to an aromatic system." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_50047 .
obo:GO_0007026 a rdfs:Class ;
rdfs:label "negative regulation of microtubule depolymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." ;
rdfs:subClassOf obo:GO_0031111 , obo:GO_0031114 , obo:GO_0065007 , obo:GO_1901880 , obo:GO_1902904 .
obo:WBPhenotype_0000247 a rdfs:Class ;
rdfs:label "sodium chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to sodium as defined by control animals. In C. elegans, sodium is typically an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001440 .
obo:GO_0000281 a rdfs:Class ;
rdfs:label "mitotic cytokinesis" ;
rdfs:comment "A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells." ;
rdfs:subClassOf obo:GO_0061640 , obo:GO_1903047 .
obo:WBPhenotype_0001020 a rdfs:Class ;
rdfs:label "embryonic lethal late emb" ;
rdfs:comment "Animals die during the final stages of embryogenesis. In C. elegans, this lethality refers to death during the last (3-fold) stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation." ;
rdfs:subClassOf obo:WBPhenotype_0000050 .
obo:WBPhenotype_0001753 a rdfs:Class ;
rdfs:label "coelomocyte uptake increased" ;
rdfs:comment "Animals exhibit intensified accumulation of fluids or fluorescent markers etc. within their coelomocytes compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001423 .
obo:PATO_0000070 a rdfs:Class ;
rdfs:label "amount" ;
rdfs:comment "The number of entities of this type that are part of the whole organism." ;
rdfs:subClassOf obo:PATO_0103000 .
obo:WBPhenotype_0000174 a rdfs:Class ;
rdfs:label "basal lamina development variant" ;
rdfs:comment "Any variation in the progression of the layer of connective tissue over the surface of tissues that serves to separate it from neighboring tissues, from its formation to its mature structure compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000619 .
obo:GO_0045901 a rdfs:Class ;
rdfs:label "positive regulation of translational elongation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translational elongation." ;
rdfs:subClassOf obo:GO_0006448 , obo:GO_0045727 , obo:GO_0065007 .
obo:GO_0071826 a rdfs:Class ;
rdfs:label "protein-RNA complex organization" ;
rdfs:comment "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." ;
rdfs:subClassOf obo:GO_0043933 .
obo:WBPhenotype_0002296 a rdfs:Class ;
rdfs:label "body posture wavelength increased" ;
rdfs:comment "Animals exhibit variations in body posture caused by an increase in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal." ;
rdfs:subClassOf obo:WBPhenotype_0002294 .
obo:GO_0099500 a rdfs:Class ;
rdfs:label "vesicle fusion to plasma membrane" ;
rdfs:comment "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." ;
rdfs:subClassOf obo:GO_0006906 , obo:GO_0140029 .
obo:WBPhenotype_0002282 a rdfs:Class ;
rdfs:label "autophagy increased" ;
rdfs:comment "Animals exhibit increased levels of the process by which their cells digest parts of their own cytoplasm, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000736 .
obo:WBPhenotype_0002303 a rdfs:Class ;
rdfs:label "nose movement increased" ;
rdfs:comment "Animals exhibit an increase in the movement of the extreme anterior portion of the body to a new location compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002301 .
obo:GO_0003824 a rdfs:Class ;
rdfs:label "catalytic activity" ;
rdfs:comment "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." ;
rdfs:subClassOf obo:GO_0003674 .
obo:WBPhenotype_0000440 a rdfs:Class ;
rdfs:label "excretory canals long" ;
rdfs:comment "The structure made by the processes of the excretory canal cell is increased in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000704 .
obo:CHEBI_52210 a rdfs:Class ;
rdfs:label "pharmacological role" ;
rdfs:comment "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:GO_0012506 a rdfs:Class ;
rdfs:label "vesicle membrane" ;
rdfs:comment "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031090 .
obo:WBPhenotype_0002177 a rdfs:Class ;
rdfs:label "plasma membrane composition variant" ;
rdfs:comment "Any variation in the components that make up the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:GO_0051647 a rdfs:Class ;
rdfs:label "nucleus localization" ;
rdfs:comment "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." ;
rdfs:subClassOf obo:GO_0051640 .
obo:WBPhenotype_0000232 a rdfs:Class ;
rdfs:label "CAN cell migration variant" ;
rdfs:comment "Variation in the migration pattern of CAN neurons. In C. elegans, CAN neurons move posteriorly from their birthplace in the head to positions near the middle of the embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001520 .
obo:GO_0010976 a rdfs:Class ;
rdfs:label "positive regulation of neuron projection development" ;
rdfs:comment "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ;
rdfs:subClassOf obo:GO_0010975 , obo:GO_0031346 , obo:GO_0065007 .
obo:GO_0009299 a rdfs:Class ;
rdfs:label "mRNA transcription" ;
rdfs:comment "The cellular synthesis of messenger RNA (mRNA) from a DNA template." ;
rdfs:subClassOf obo:GO_0006351 , obo:GO_0016071 .
obo:WBPhenotype_0001825 a rdfs:Class ;
rdfs:label "rudimentary gonad" ;
rdfs:comment "Animals have very few or no germline nuclei and gonad arms that are very small or missing." ;
rdfs:subClassOf obo:WBPhenotype_0001355 .
obo:WBPhenotype_0001689 a rdfs:Class ;
rdfs:label "surface antigen negative" ;
rdfs:comment "Cuticles or cuticular extracts do not bind antibodies that are observed to bind the surfaces or cuticular extracts of Bristol N2 animals of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0001687 .
obo:WBPhenotype_0001222 a rdfs:Class ;
rdfs:label "transposon mutator" ;
rdfs:comment "Animals exhibit an increase in frequency of transposition events (DNA movement to different positions within the genome of a single cell) causing an accumulation of lesions within the genome, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000228 .
obo:CHEBI_64459 a rdfs:Class ;
rdfs:label "biaryl" ;
rdfs:comment "An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond." ;
rdfs:subClassOf obo:CHEBI_33659 .
obo:WBls_0000820 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during L3 larval stage"@en ;
rdfs:comment "A C. elegans life stage that occurs during the L3 larval life stage" ;
rdfs:subClassOf obo:WBls_0000817 .
obo:WBPhenotype_0000070 a rdfs:Class ;
rdfs:label "male tail morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of the somatic reproductive components of the posterior segment of the male from that observed in control males. In C. elegans, this region of the male includes the terminal canals of the reproductive tract, the digestive tract, and spicule channels along with the male specific sensilla (ray, post-cloacal, hook and spicule) and extends to the tip of the acellular fan." ;
rdfs:subClassOf obo:WBPhenotype_0000073 , obo:WBPhenotype_0001024 .
obo:WBPhenotype_0000858 a rdfs:Class ;
rdfs:label "excretory duct cell development variant" ;
rdfs:comment "Variations in the progression of an interfacial epithelial cell which forms a lumen to receive the outflow of the excretory gland and excretory canal cells, over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000621 .
obo:CHEBI_48219 a rdfs:Class ;
rdfs:label "disinfectant" ;
rdfs:comment "An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity." ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:GO_1902099 a rdfs:Class ;
rdfs:label "regulation of metaphase/anaphase transition of cell cycle" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle." ;
rdfs:subClassOf obo:GO_0033045 , obo:GO_0065007 , obo:GO_1901987 .
obo:GO_0005911 a rdfs:Class ;
rdfs:label "cell-cell junction" ;
rdfs:comment "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." ;
rdfs:subClassOf obo:GO_0070161 .
obo:GO_0045947 a rdfs:Class ;
rdfs:label "negative regulation of translational initiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0017148 , obo:GO_0065007 .
obo:CHEBI_36358 a rdfs:Class ;
rdfs:label "polyatomic ion" ;
rdfs:comment "An ion consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_24870 , obo:CHEBI_36357 .
obo:PATO_0001549 a rdfs:Class ;
rdfs:label "increased sensitivity toward" ;
rdfs:comment "A sensitivity toward an external stimulus which is higher than normal/average." ;
rdfs:subClassOf obo:PATO_0000516 , obo:PATO_0002305 .
obo:WBPhenotype_0000332 a rdfs:Class ;
rdfs:label "inhibitors of sodium potassium ATPase hypersensitive" ;
rdfs:comment "Animals respond to inhibitors of sodium potassium ATPase at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 .
obo:WBPhenotype_0002331 a rdfs:Class ;
rdfs:label "obsolete temporal frequency of sinusoidal movement increased" ;
rdfs:comment "OBSOLETE." .
obo:GO_0016788 a rdfs:Class ;
rdfs:label "hydrolase activity, acting on ester bonds" ;
rdfs:comment "Catalysis of the hydrolysis of any ester bond." ;
rdfs:subClassOf obo:GO_0016787 .
obo:GO_1903326 a rdfs:Class ;
rdfs:label "regulation of tRNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of tRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051252 , obo:GO_0065007 .
obo:WBPhenotype_0002215 a rdfs:Class ;
rdfs:label "fewer body wall muscles" ;
rdfs:comment "Any variation that results in a fewer than control number of body wall muscle cells." ;
rdfs:subClassOf obo:WBPhenotype_0001597 .
obo:CHEBI_33285 a rdfs:Class ;
rdfs:label "heteroorganic entity" ;
rdfs:comment "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:GO_0005604 a rdfs:Class ;
rdfs:label "basement membrane" ;
rdfs:comment "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." ;
rdfs:subClassOf obo:GO_0031012 .
obo:WBPhenotype_0000977 a rdfs:Class ;
rdfs:label "somatic gonad morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of the components of the gonad that are separate from the germline proper compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001355 .
obo:CHEBI_23449 a rdfs:Class ;
rdfs:label "cyclic peptide" ;
rdfs:subClassOf obo:CHEBI_16670 .
obo:CL_0000404 a rdfs:Class ;
rdfs:label "electrically signaling cell" ;
rdfs:comment "A cell that initiates an electrical signal and passes that signal to another cell." ;
rdfs:subClassOf obo:CL_0000211 .
obo:GO_2000147 a rdfs:Class ;
rdfs:label "positive regulation of cell motility" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell motility." ;
rdfs:subClassOf obo:GO_0040017 , obo:GO_0048522 , obo:GO_0065007 , obo:GO_2000145 .
obo:GO_0099575 a rdfs:Class ;
rdfs:label "regulation of protein catabolic process at presynapse, modulating synaptic transmission" ;
rdfs:comment "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." ;
rdfs:subClassOf obo:GO_0042176 , obo:GO_0099171 .
obo:WBPhenotype_0000282 a rdfs:Class ;
rdfs:label "hermaphrodite sex muscle development variant" ;
rdfs:comment "Variations in the progression of the muscles of the adult hermaphrodite reproductive system over time form their initial formation to their mature structure compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000669 .
obo:WBls_0000010 a rdfs:Class ;
rdfs:label "gastrulating embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 100-290min after first cleavage at 20 Centigrade. Proliferate from 28 cells to 421 cells. Referring to the whole period of gastrulation." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000814 .
obo:PATO_0001192 a rdfs:Class ;
rdfs:label "hyperresponsive to" ;
rdfs:comment "A response quality inhering in a bearer by virtue of the bearer's excessive reaction to a stimulus or an agent." ;
rdfs:subClassOf obo:PATO_0000487 , obo:PATO_0002305 .
obo:WBPhenotype_0002187 a rdfs:Class ;
rdfs:label "cell fate transformation to body wall muscle" ;
rdfs:comment "Animals develop body wall muscle from precursor cells that do not normally produce body wall muscle." ;
rdfs:subClassOf obo:WBPhenotype_0000414 .
obo:GO_2000020 a rdfs:Class ;
rdfs:label "positive regulation of male gonad development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of male gonad development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905941 , obo:GO_2000018 .
obo:CHEBI_18059 a rdfs:Class ;
rdfs:label "lipid" ;
rdfs:comment "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:WBPhenotype_0000204 a rdfs:Class ;
rdfs:label "anterior body contraction defecation cycle variant" ;
rdfs:comment "Variations in the anterior body muscle contraction (aBoc) step of the defecation cycle compared to control animals. Under normal conditions, anterior body wall muscles contract and pressurize the intestinal contents during the aBoc step." ;
rdfs:subClassOf obo:WBPhenotype_0001476 .
obo:CHEBI_33461 a rdfs:Class ;
rdfs:label "phosphorus oxoanion" ;
rdfs:subClassOf obo:CHEBI_24834 , obo:CHEBI_26082 , obo:CHEBI_33459 .
obo:WBPhenotype_0000726 a rdfs:Class ;
rdfs:label "ligand binding variant" ;
rdfs:comment "Any variation of the specific binding of a molecule to its partner, which typically results in a change in cell activity, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000727 .
obo:WBPhenotype_0002314 a rdfs:Class ;
rdfs:label "turning frequency reduced" ;
rdfs:comment "Animals exhibit a decrease in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." ;
rdfs:subClassOf obo:WBPhenotype_0002312 .
obo:CHEBI_38462 a rdfs:Class ;
rdfs:label "EC 3.1.1.7 (acetylcholinesterase) inhibitor" ;
rdfs:comment "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid." ;
rdfs:subClassOf obo:CHEBI_76773 .
obo:GO_0043558 a rdfs:Class ;
rdfs:label "regulation of translational initiation in response to stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0043555 , obo:GO_0065007 .
obo:WBPhenotype_0000751 a rdfs:Class ;
rdfs:label "L1 larval development variant" ;
rdfs:comment "Variations in the progression of a newly hatched animal through the first larval molt compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000750 .
obo:WBPhenotype_0002598 a rdfs:Class ;
rdfs:label "gustatory aversive learning abnormal"@en ;
rdfs:comment "Variations in the aversion of animals to substances sensed by gustation (taste) previously associated with an aversive stimuli during a gustation training protocol, compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype will not exhibit the same aversion to the substance as compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002597 .
obo:GO_0032465 a rdfs:Class ;
rdfs:label "regulation of cytokinesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0051302 , obo:GO_0065007 .
obo:GO_0050765 a rdfs:Class ;
rdfs:label "negative regulation of phagocytosis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis." ;
rdfs:subClassOf obo:GO_0045806 , obo:GO_0050764 , obo:GO_0065007 .
obo:GO_0042326 a rdfs:Class ;
rdfs:label "negative regulation of phosphorylation" ;
rdfs:comment "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." ;
rdfs:subClassOf obo:GO_0042325 , obo:GO_0045936 , obo:GO_0065007 .
obo:CHEBI_38070 a rdfs:Class ;
rdfs:label "anti-arrhythmia drug" ;
rdfs:comment "A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres." ;
rdfs:subClassOf obo:CHEBI_35554 .
obo:GO_0032839 a rdfs:Class ;
rdfs:label "dendrite cytoplasm" ;
rdfs:comment "All of the contents of a dendrite, excluding the surrounding plasma membrane." ;
rdfs:subClassOf obo:GO_0005737 , obo:GO_0120111 .
obo:CHEBI_37750 a rdfs:Class ;
rdfs:label "chlorine oxide" ;
rdfs:subClassOf obo:CHEBI_37749 .
obo:WBPhenotype_0000659 a rdfs:Class ;
rdfs:label "feeding behavior variant" ;
rdfs:comment "Behavior associated with the intake of food is altered compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:WBPhenotype_0001388 a rdfs:Class ;
rdfs:label "organism hypersensitive gamma irradiation" ;
rdfs:comment "Organisms respond to a lower dosage of gamma rays or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000497 , obo:WBPhenotype_0000711 .
obo:GO_0050714 a rdfs:Class ;
rdfs:label "positive regulation of protein secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." ;
rdfs:subClassOf obo:GO_0050708 , obo:GO_0051222 , obo:GO_0065007 , obo:GO_1903532 .
obo:WBPhenotype_0002651 a rdfs:Class ;
rdfs:label "exopher production phenotype"@en ;
rdfs:comment "Cells exhibit an abnormal production of exophers, large (approximately four microns in diameter) membrane-bound extracellular vesicles that are released by budding out of cells into the extracellular space, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000258 .
obo:WBPhenotype_0001814 a rdfs:Class ;
rdfs:label "crossover defective" ;
rdfs:comment "Animals exhibit defects in the number or extent of connections between chromatids that occur during the process of genetic material exchange between homologous segments of non-sister chromatids." ;
rdfs:subClassOf obo:WBPhenotype_0002012 .
obo:CHEBI_64049 a rdfs:Class ;
rdfs:label "food acidity regulator" ;
rdfs:comment "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." ;
rdfs:subClassOf obo:CHEBI_64047 .
obo:WBPhenotype_0001121 a rdfs:Class ;
rdfs:label "exaggerated asynchrony early emb" ;
rdfs:comment "Asynchrony of the second division is exaggerated and P1 divides more slowly than normal." ;
rdfs:subClassOf obo:WBPhenotype_0001120 .
obo:CHEBI_48540 a rdfs:Class ;
rdfs:label "beta-adrenergic drug" ;
rdfs:comment "Any of the drugs that act on β-adrenergic receptors." ;
rdfs:subClassOf obo:CHEBI_37962 .
obo:WBPhenotype_0002386 a rdfs:Class ;
rdfs:label "fibrous body-membranous organelle (FB-MO) assembly variant" ;
rdfs:comment "Animals exhibit variations in the assembly of the fibrous body-membranous organelle (FB-MO), a nematode sperm-specific organelle involved in cytoplasmic partitioning during spermatogenesis, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001344 .
obo:CHEBI_17792 a rdfs:Class ;
rdfs:label "organohalogen compound" ;
rdfs:comment "A compound containing at least one carbon-halogen bond (where X is a halogen atom)." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_37578 .
obo:GO_0045833 a rdfs:Class ;
rdfs:label "negative regulation of lipid metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0019216 , obo:GO_0065007 .
obo:WBbt_0005786 a rdfs:Class ;
rdfs:label "muscle of the reproductive system" ;
rdfs:subClassOf obo:WBbt_0003675 .
obo:GO_0000048 a rdfs:Class ;
rdfs:label "peptidyltransferase activity" ;
rdfs:comment "Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme." ;
rdfs:subClassOf obo:GO_0016755 , obo:GO_0140096 , obo:GO_0140101 .
obo:WBPhenotype_0001576 a rdfs:Class ;
rdfs:label "mitochondria spacing variant" ;
rdfs:comment "Variations in the spatial distribution of the mitochondria within the cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001401 , obo:WBPhenotype_0002098 .
obo:WBPhenotype_0001609 a rdfs:Class ;
rdfs:label "isoflurane hypersensitive" ;
rdfs:comment "Animals respond to the anesthetic isoflurane at lower concentrations or shorter response times than control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000008 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000467 a rdfs:Class ;
rdfs:label "age associated fluorescence increased" ;
rdfs:comment "Animals exhibit an increase in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001009 .
obo:GO_0008038 a rdfs:Class ;
rdfs:label "neuron recognition" ;
rdfs:comment "The process in which a neuronal cell in a multicellular organism interprets its surroundings." ;
rdfs:subClassOf obo:GO_0008037 .
obo:WBPhenotype_0001294 a rdfs:Class ;
rdfs:label "head bent" ;
rdfs:comment "The most anterior portion of the animal is not aligned with the axis of the body." ;
rdfs:subClassOf obo:WBPhenotype_0000071 .
obo:GO_1902437 a rdfs:Class ;
rdfs:label "positive regulation of male mating behavior" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of male mating behavior." ;
rdfs:subClassOf obo:GO_0048520 , obo:GO_0065007 , obo:GO_1902435 , obo:GO_2000243 .
obo:GO_0051094 a rdfs:Class ;
rdfs:label "positive regulation of developmental process" ;
rdfs:comment "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0006970 a rdfs:Class ;
rdfs:label "response to osmotic stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0009628 .
obo:GO_0007097 a rdfs:Class ;
rdfs:label "nuclear migration" ;
rdfs:comment "The directed movement of the nucleus to a specific location within a cell." ;
rdfs:subClassOf obo:GO_0046907 , obo:GO_0051647 , obo:GO_0051656 .
obo:GO_0031399 a rdfs:Class ;
rdfs:label "regulation of protein modification process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ;
rdfs:subClassOf obo:GO_0051246 , obo:GO_0065007 .
obo:CHEBI_35705 a rdfs:Class ;
rdfs:label "immunosuppressive agent" ;
rdfs:comment "An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response." ;
rdfs:subClassOf obo:CHEBI_50846 .
obo:WBPhenotype_0001254 a rdfs:Class ;
rdfs:label "amphid channel cilia bulbous" ;
rdfs:comment "The dendritic processes that normally extend through the amphid sensillum pore to the outside are truncated and have swollen ends as opposed to the extended and finger-like tips of channel cilia in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001249 .
obo:PATO_0000300 a rdfs:Class ;
rdfs:label "immobile" ;
rdfs:comment "A mobility quality inhering in a bearer by virtue of the bearer's being incapable to move freely." ;
rdfs:subClassOf obo:PATO_0000004 .
obo:WBls_0000021 a rdfs:Class ;
rdfs:label "fully-elongated embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000811 .
obo:WBPhenotype_0001328 a rdfs:Class ;
rdfs:label "posterior body dumpy" ;
rdfs:comment "The posterior part of the worm is shorter and stouter compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000793 .
obo:CHEBI_33838 a rdfs:Class ;
rdfs:label "nucleoside" ;
rdfs:comment "An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents." ;
rdfs:subClassOf obo:CHEBI_21731 , obo:CHEBI_26912 , obo:CHEBI_61120 .
obo:WBPhenotype_0002088 a rdfs:Class ;
rdfs:label "hypersensitive to dauer pheromone" ;
rdfs:comment "Animals respond to dauer pheromone at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001479 .
obo:WBPhenotype_0000607 a rdfs:Class ;
rdfs:label "coelomic system physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the coelomic system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000575 .
obo:PATO_0001490 a rdfs:Class ;
rdfs:label "heterochronic growth" ;
rdfs:comment "A growth quality of a process inhering in an organism, structure, or group of organisms by virtue of the bearer's reduced or increased growth." ;
rdfs:subClassOf obo:PATO_0001433 .
obo:WBPhenotype_0002027 a rdfs:Class ;
rdfs:label "gonad independent vulva differentiation" ;
rdfs:comment "VPCs differentiate in the absence of inductive signals coming from the gonad." ;
rdfs:subClassOf obo:WBPhenotype_0000354 , obo:WBPhenotype_0001272 .
obo:GO_0046929 a rdfs:Class ;
rdfs:label "negative regulation of neurotransmitter secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." ;
rdfs:subClassOf obo:GO_0046928 , obo:GO_0051589 , obo:GO_0065007 , obo:GO_1903531 .
obo:WBPhenotype_0002139 a rdfs:Class ;
rdfs:label "linker cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the linker cell compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002108 .
obo:CHEBI_33719 a rdfs:Class ;
rdfs:label "alpha-amino-acid cation" ;
rdfs:subClassOf obo:CHEBI_33703 .
obo:WBPhenotype_0001854 a rdfs:Class ;
rdfs:label "benomyl response variant" ;
rdfs:comment "Animals exhibit variations in their response to the microtubule-depolymerizing drug benomyl, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:CHEBI_22323 a rdfs:Class ;
rdfs:label "alkyl group" ;
rdfs:comment "A univalent group ‒CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom." ;
rdfs:subClassOf obo:CHEBI_33248 .
obo:WBPhenotype_0002587 a rdfs:Class ;
rdfs:label "Pluronic gel burrowing impaired"@en ;
rdfs:comment "Animals are impaired in their burrowing ability compared to control animals in a Pluronic gel-based burrowing assay." ;
rdfs:subClassOf obo:WBPhenotype_0002559 .
obo:WBPhenotype_0002208 a rdfs:Class ;
rdfs:label "antibody temporal expression variant" ;
rdfs:comment "The expression of a protein, as determined by antibody staining, varied from controls with respect to timing such that the protein was observed to be expressed at earlier timepoints or later timepoints than controls." ;
rdfs:subClassOf obo:WBPhenotype_0000424 .
obo:WBPhenotype_0000048 a rdfs:Class ;
rdfs:label "hatching variant" ;
rdfs:comment "Variations in the ability of an animal to emerge from the protective egg shell compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:CHEBI_33256 a rdfs:Class ;
rdfs:label "primary amide" ;
rdfs:comment "A derivative of an oxoacid RkE(=O)l(OH)m (l ≠ 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ;
rdfs:subClassOf obo:CHEBI_32988 .
obo:WBPhenotype_0001110 a rdfs:Class ;
rdfs:label "aster defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0002419 .
obo:WBPhenotype_0001802 a rdfs:Class ;
rdfs:label "body wall muscle relaxation defective" ;
rdfs:comment "Animals fail to relax their body wall muscles to the same extent as muscles in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000596 .
obo:WBPhenotype_0001773 a rdfs:Class ;
rdfs:label "enhanced locomotion defective" ;
rdfs:comment "Animals do not exhibit an increase in speed when placed in an environment that relies on a combination of swimming and crawling behaviors compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001206 .
obo:GO_1905809 a rdfs:Class ;
rdfs:label "negative regulation of synapse organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization." ;
rdfs:subClassOf obo:GO_0050807 , obo:GO_0051129 , obo:GO_0065007 .
obo:WBPhenotype_0001921 a rdfs:Class ;
rdfs:label "meiotic DNA double strand break formation variant" ;
rdfs:comment "Any variation in the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination." ;
rdfs:subClassOf obo:WBPhenotype_0000775 .
obo:GO_0007635 a rdfs:Class ;
rdfs:label "chemosensory behavior" ;
rdfs:comment "Behavior that is dependent upon the sensation of chemicals." ;
rdfs:subClassOf obo:GO_0007610 .
obo:CHEBI_24469 a rdfs:Class ;
rdfs:label "haloalkane" ;
rdfs:comment "A halohydrocarbon that is an alkane in which at least one hydrogen atom has been replaced by with a halogen atom." ;
rdfs:subClassOf obo:CHEBI_24472 .
obo:WBPhenotype_0002324 a rdfs:Class ;
rdfs:label "backward point velocity decreased" ;
rdfs:comment "Animals exhibit decreased velocity of backward translocation of any point along the animal's track from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002323 .
obo:GO_0033048 a rdfs:Class ;
rdfs:label "negative regulation of mitotic sister chromatid segregation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." ;
rdfs:subClassOf obo:GO_0033046 , obo:GO_0033047 , obo:GO_0065007 .
obo:GO_0034762 a rdfs:Class ;
rdfs:label "regulation of transmembrane transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0051049 , obo:GO_0065007 .
obo:CHEBI_36810 a rdfs:Class ;
rdfs:label "(trifluoromethyl)benzene" ;
rdfs:comment "A fluorohydrocarbon that is fluoroform in which the hydrogen is substituted by a phenyl group." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_46695 , obo:CHEBI_83565 .
obo:GO_0031987 a rdfs:Class ;
rdfs:label "locomotion involved in locomotory behavior" ;
rdfs:comment "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ;
rdfs:subClassOf obo:GO_0040011 .
obo:PATO_0001242 a rdfs:Class ;
rdfs:label "wavelength" ;
rdfs:comment "A physical quality which is equal to the distance between repeating units of a wave pattern." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:WBbt_0006754 a rdfs:Class ;
rdfs:label "amphid sheath cell" ;
rdfs:comment "sheath cell of amphid sensillum." ;
rdfs:subClassOf obo:WBbt_0005811 .
obo:CHEBI_33561 a rdfs:Class ;
rdfs:label "d-block element atom" ;
rdfs:subClassOf obo:CHEBI_27081 .
obo:CHEBI_78433 a rdfs:Class ;
rdfs:label "refrigerant" ;
rdfs:comment "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:UBERON_0000483 a rdfs:Class .
obo:WBPhenotype_0001002 a rdfs:Class ;
rdfs:label "head muscle behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of the head muscles in response to external or internal stimuli compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000595 .
obo:WBPhenotype_0000391 a rdfs:Class ;
rdfs:label "defecation missing motor steps" ;
rdfs:comment "Animals lack one or more of the stereotyped muscle contractions that result in defecation compared to control. In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp)." ;
rdfs:subClassOf obo:WBPhenotype_0000650 .
obo:CHEBI_51737 a rdfs:Class ;
rdfs:label "alpha,beta-unsaturated carboxylic ester" ;
rdfs:comment "A carboxylic ester of general formula R1R2C=CR3‒C(=O)OR4 (R4 ≠ H) or R1C≡C‒C(=O)OR2 (R2 ≠ H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_33308 .
obo:CHEBI_7035 a rdfs:Class ;
rdfs:label "muscimol" ;
rdfs:comment "A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita." ;
rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_50994 , obo:CHEBI_55373 .
obo:CHEBI_46800 a rdfs:Class ;
rdfs:label "ethanethioic O-acid" ;
rdfs:subClassOf obo:CHEBI_26952 .
obo:WBPhenotype_0000473 a rdfs:Class ;
rdfs:label "progressive paralysis" ;
rdfs:comment "Animals become increasingly sluggish/immobilized as they age." ;
rdfs:subClassOf obo:WBPhenotype_0000644 .
obo:WBPhenotype_0001720 a rdfs:Class ;
rdfs:label "spermatozoa retro location defective" ;
rdfs:comment "Spermatozoa do not crawl back into the spermatheca after being swept into the uterus by passing oocytes." ;
rdfs:subClassOf obo:WBPhenotype_0000389 , obo:WBPhenotype_0001386 .
obo:GO_0052689 a rdfs:Class ;
rdfs:label "carboxylic ester hydrolase activity" ;
rdfs:comment "Catalysis of the hydrolysis of a carboxylic ester bond." ;
rdfs:subClassOf obo:GO_0016788 .
obo:GO_0110028 a rdfs:Class ;
rdfs:label "positive regulation of mitotic spindle organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic spindle organization." ;
rdfs:subClassOf obo:GO_0045931 , obo:GO_0051495 , obo:GO_0060236 , obo:GO_0065007 , obo:GO_0090068 .
obo:WBPhenotype_0000311 a rdfs:Class ;
rdfs:label "obsolete semi sterile" ;
rdfs:comment "OBSOLETE." .
obo:CHEBI_33497 a rdfs:Class ;
rdfs:label "transition element molecular entity" ;
rdfs:comment "A molecular entity containing one or more atoms of a transition element." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:WBPhenotype_0002537 a rdfs:Class ;
rdfs:label "P granule number reduced"@en ;
rdfs:comment "Animals exhibit germ cells with a reduced number of P granules compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002536 .
obo:WBPhenotype_0002233 a rdfs:Class ;
rdfs:label "osmolarity modulated swimming variant" ;
rdfs:comment "The swimming behavior of animals are influenced or modulate by the osmolarity of the swimming buffer. The swimming of wild-type C. elegans animals are not affected by the osmolarity of the swimming liquid." ;
rdfs:subClassOf obo:WBPhenotype_0000876 .
obo:GO_0005634 a rdfs:Class ;
rdfs:label "nucleus" ;
rdfs:comment "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." ;
rdfs:subClassOf obo:GO_0043231 .
obo:CHEBI_50320 a rdfs:Class ;
rdfs:label "nucleoside residue" ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:WBPhenotype_0002561 a rdfs:Class ;
rdfs:label "homotypic endosome fusion defective"@en ;
rdfs:comment "Cells exhibit defects in the homotypic fusion of endosomes." ;
rdfs:subClassOf obo:WBPhenotype_0001422 .
obo:GO_0060409 a rdfs:Class ;
rdfs:label "positive regulation of acetylcholine metabolic process" ;
rdfs:comment "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ;
rdfs:subClassOf obo:GO_0033240 , obo:GO_0060408 , obo:GO_0065007 .
obo:WBPhenotype_0000038 a rdfs:Class ;
rdfs:label "exploded through vulva" ;
rdfs:comment "The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture." ;
rdfs:subClassOf obo:WBPhenotype_0000619 .
obo:GO_0016310 a rdfs:Class ;
rdfs:label "phosphorylation" ;
rdfs:comment "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." ;
rdfs:subClassOf obo:GO_0006796 .
obo:GO_0008406 a rdfs:Class ;
rdfs:label "gonad development" ;
rdfs:comment "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048608 .
obo:CHEBI_24533 a rdfs:Class ;
rdfs:label "heterodetic cyclic peptide" ;
rdfs:comment "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." ;
rdfs:subClassOf obo:CHEBI_23449 .
obo:PATO_0000596 a rdfs:Class ;
rdfs:label "decreased volume" ;
rdfs:comment "A volume which is relatively low." ;
rdfs:subClassOf obo:PATO_0000587 , obo:PATO_0000918 .
obo:GO_0045089 a rdfs:Class ;
rdfs:label "positive regulation of innate immune response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." ;
rdfs:subClassOf obo:GO_0002833 , obo:GO_0031349 , obo:GO_0032103 , obo:GO_0045088 , obo:GO_0050778 , obo:GO_0065007 .
obo:GO_0062125 a rdfs:Class ;
rdfs:label "regulation of mitochondrial gene expression" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0065007 .
obo:WBPhenotype_0000629 a rdfs:Class ;
rdfs:label "excess neurite outgrowth" ;
rdfs:comment "Any variation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated." ;
rdfs:subClassOf obo:WBPhenotype_0000572 .
obo:CHEBI_33639 a rdfs:Class ;
rdfs:label "ortho- and peri-fused compound" ;
rdfs:comment "A polycyclic compound in which one ring contains two, and only two, atoms in common with each of two or more rings of a contiguous series of rings. Such compounds have n common faces and less than 2n common atoms." ;
rdfs:subClassOf obo:CHEBI_35293 .
obo:WBPhenotype_0000451 a rdfs:Class ;
rdfs:label "head protrusion" ;
rdfs:comment "Any irregular swelling in discrete regions of the head." ;
rdfs:subClassOf obo:WBPhenotype_0000071 .
obo:WBPhenotype_0004012 a rdfs:Class ;
rdfs:label "sperm transfer continuation defective" ;
rdfs:comment "Any variation in the continued movement of sperm through the vas deferens, exiting the cloaca, compared to control. In C. elegans, when all sperm that exit the seminal vesicle have been released, the spicules retract into the male." ;
rdfs:subClassOf obo:WBPhenotype_0000284 .
obo:WBPhenotype_0000514 a rdfs:Class ;
rdfs:label "rubber band" ;
rdfs:comment "When prodded on the head, worm contracts and then relaxes along its entire body without moving backwards, compared to a control worm which contracts its anterior end and backs away in response to prodding." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:GO_0003012 a rdfs:Class ;
rdfs:label "muscle system process" ;
rdfs:comment "An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." ;
rdfs:subClassOf obo:GO_0003008 .
obo:GO_1905821 a rdfs:Class ;
rdfs:label "positive regulation of chromosome condensation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chromosome condensation." ;
rdfs:subClassOf obo:GO_0060623 , obo:GO_0065007 , obo:GO_2001252 .
obo:WBPhenotype_0001910 a rdfs:Class ;
rdfs:label "kinetochore organization variant" ;
rdfs:comment "Animals exhibit variations in the assembly, arrangement, orientation, or disassembly of the kinetochore, a multisubunit protein complex on chromosomes where the spindle fibers attach during cell division to pull the chromosomes apart." ;
rdfs:subClassOf obo:WBPhenotype_0001348 .
obo:WBPhenotype_0002526 a rdfs:Class ;
rdfs:label "response to molybdenum cofactor depletion abnormal"@en ;
rdfs:comment "Animals exhibit variations in the response to the depletion of molybdenum cofactor from the diet compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002525 .
obo:WBPhenotype_0001120 a rdfs:Class ;
rdfs:label "relative cell cycle timing defective early emb" ;
rdfs:comment "Relative cell cycle timing during the first four cell divisions is aberrant." ;
rdfs:subClassOf obo:WBPhenotype_0001115 .
obo:GO_0051295 a rdfs:Class ;
rdfs:label "establishment of meiotic spindle localization" ;
rdfs:comment "The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs." ;
rdfs:subClassOf obo:GO_0051293 , obo:GO_1903046 .
obo:GO_1903046 a rdfs:Class ;
rdfs:label "meiotic cell cycle process" ;
rdfs:comment "A process that is part of the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0022402 , obo:GO_0022414 .
obo:WBPhenotype_0000163 a rdfs:Class ;
rdfs:label "clear larva" ;
rdfs:comment "Larva appear unusually transparent when compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000890 , obo:WBPhenotype_0001010 .
obo:GO_2000114 a rdfs:Class ;
rdfs:label "regulation of establishment of cell polarity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of establishment of cell polarity." ;
rdfs:subClassOf obo:GO_0032878 , obo:GO_0065007 .
obo:GO_0040019 a rdfs:Class ;
rdfs:label "positive regulation of embryonic development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of embryonic development." ;
rdfs:subClassOf obo:GO_0045995 , obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0031965 a rdfs:Class ;
rdfs:label "nuclear membrane" ;
rdfs:comment "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031090 .
obo:WBPhenotype_0002545 a rdfs:Class ;
rdfs:label "response to bacteria variant"@en ;
rdfs:comment "Animals exhibit variations in their response to bacteria (pathogenic or non-pathogenic), compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:GO_0005623 a rdfs:Class ;
rdfs:label "obsolete cell" ;
rdfs:comment "OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." .
obo:WBPhenotype_0001299 a rdfs:Class ;
rdfs:label "cell division variant male" ;
rdfs:comment "Any variation that alters the physical partitioning and separation of a cell into daughter cells in male animals compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:WBPhenotype_0001306 a rdfs:Class ;
rdfs:label "male reproductive system morphology variant" ;
rdfs:comment "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the male reproductive system compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." ;
rdfs:subClassOf obo:WBPhenotype_0000605 .
obo:PATO_0000328 a rdfs:Class ;
rdfs:label "low saturation" ;
rdfs:comment "A color saturation which is of low purity." ;
rdfs:subClassOf obo:PATO_0000017 .
obo:GO_0050927 a rdfs:Class ;
rdfs:label "positive regulation of positive chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." ;
rdfs:subClassOf obo:GO_0050921 , obo:GO_0050926 , obo:GO_0065007 .
obo:GO_1900193 a rdfs:Class ;
rdfs:label "regulation of oocyte maturation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of oocyte maturation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903429 , obo:GO_2000241 .
obo:CHEBI_29228 a rdfs:Class ;
rdfs:label "hydrogen fluoride" ;
rdfs:comment "A diatomic molecule containing covalently bonded hydrogen and fluorine atoms." ;
rdfs:subClassOf obo:CHEBI_18140 , obo:CHEBI_37176 .
obo:WBPhenotype_0002198 a rdfs:Class ;
rdfs:label "neuromuscular junction organization variant" ;
rdfs:comment "The proper localization and assembly of components at the junction of a neuron with a muscle cell varies from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000625 .
obo:GO_0099550 a rdfs:Class ;
rdfs:label "trans-synaptic signaling, modulating synaptic transmission" ;
rdfs:comment "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0099537 .
obo:CHEBI_76971 a rdfs:Class ;
rdfs:label "Escherichia coli metabolite" ;
rdfs:comment "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." ;
rdfs:subClassOf obo:CHEBI_76969 .
obo:WBPhenotype_0002487 a rdfs:Class ;
rdfs:label "intestinal integrity variant"@en ;
rdfs:comment "Animals exhibit variations in the integrity of the intestine, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001093 .
obo:WBPhenotype_0001511 a rdfs:Class ;
rdfs:label "linker cell migration variant" ;
rdfs:comment "Variations in the stereotypical migration pattern of the linker cell in a developing male compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000594 .
obo:CHEBI_35678 a rdfs:Class ;
rdfs:label "histamine agonist" ;
rdfs:comment "A drug that binds to and activates histamine receptors. Although they have been suggested for a variety of clinical applications, histamine agonists have so far been more widely used in research than therapeutically." ;
rdfs:subClassOf obo:CHEBI_37957 .
obo:WBPhenotype_0000670 a rdfs:Class ;
rdfs:label "spermatogenesis variant" ;
rdfs:comment "Any variation in the processes that influence the generation and maturation of spermatozoa (motile sperm) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000894 .
obo:CHEBI_85234 a rdfs:Class ;
rdfs:label "human blood serum metabolite" ;
rdfs:comment "Any metabolite (endogenous or exogenous) found in human blood serum samples." ;
rdfs:subClassOf obo:CHEBI_77746 .
obo:GO_1901075 a rdfs:Class ;
rdfs:label "negative regulation of engulfment of apoptotic cell" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell." ;
rdfs:subClassOf obo:GO_0060101 , obo:GO_0065007 , obo:GO_1901074 , obo:GO_2000426 .
obo:WBPhenotype_0001453 a rdfs:Class ;
rdfs:label "high sodium chloride concentration osmotic avoidance variant" ;
rdfs:comment "Animals exhibit variations in their avoidance response to high concentrations of sodium chloride solution compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000663 .
obo:WBPhenotype_0000930 a rdfs:Class ;
rdfs:label "sexually dimorphic development variant" ;
rdfs:comment "Variations in the progression of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000531 .
obo:WBPhenotype_0000321 a rdfs:Class ;
rdfs:label "nose morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000071 .
obo:WBPhenotype_0001016 a rdfs:Class ;
rdfs:label "larval growth variant" ;
rdfs:comment "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the larval stages compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001015 .
obo:GO_0099636 a rdfs:Class ;
rdfs:label "cytoplasmic streaming" ;
rdfs:comment "The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains." ;
rdfs:subClassOf obo:GO_0046907 .
obo:WBPhenotype_0000293 a rdfs:Class ;
rdfs:label "alimentary system pigmentation variant" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the alimentary system." ;
rdfs:subClassOf obo:WBPhenotype_0000292 , obo:WBPhenotype_0000598 .
obo:GO_0090174 a rdfs:Class ;
rdfs:label "organelle membrane fusion" ;
rdfs:comment "The joining of two lipid bilayers to form a single organelle membrane." ;
rdfs:subClassOf obo:GO_0048284 , obo:GO_0061025 .
obo:PATO_0001472 a rdfs:Class ;
rdfs:label "decreased depth" ;
rdfs:comment "A depth which is relatively low." ;
rdfs:subClassOf obo:PATO_0000587 , obo:PATO_0001595 .
obo:WBPhenotype_0000491 a rdfs:Class ;
rdfs:label "isthmus morphology defective" ;
rdfs:comment "Any observed morphological defects of the isthmus." ;
rdfs:subClassOf obo:WBPhenotype_0000709 .
obo:WBPhenotype_0000737 a rdfs:Class ;
rdfs:label "germ cell resistant ionizing radiation" ;
rdfs:comment "Germ cells fail to respond to the dosage of ion producing radiation that elicits a response in control animals. Alternatively, germ cells require a higher dosage or a longer exposure to ion producing radiation to elicit the same response as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000712 .
obo:GO_0016818 a rdfs:Class ;
rdfs:label "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides" ;
rdfs:comment "Catalysis of the hydrolysis of any acid anhydride which contains phosphorus." ;
rdfs:subClassOf obo:GO_0016817 .
obo:CHEBI_27780 a rdfs:Class ;
rdfs:label "detergent" ;
rdfs:comment "A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions." ;
rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_35195 .
obo:GO_0051128 a rdfs:Class ;
rdfs:label "regulation of cellular component organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0009057 a rdfs:Class ;
rdfs:label "macromolecule catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0043170 .
obo:GO_0030336 a rdfs:Class ;
rdfs:label "negative regulation of cell migration" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 , obo:GO_2000146 .
obo:WBbt_0005319 a rdfs:Class ;
rdfs:label "spermatheca" ;
rdfs:comment "an accordion-like tube that contains sperm and is the site of oocyte fertilization." ;
rdfs:subClassOf obo:WBbt_0005758 .
obo:PATO_0001834 a rdfs:Class ;
rdfs:label "decreased fertility" ;
rdfs:comment "A fertility which is relatively low." ;
rdfs:subClassOf obo:PATO_0000955 , obo:PATO_0002303 .
obo:WBPhenotype_0002382 a rdfs:Class ;
rdfs:label "resistant to bioactive compound" ;
rdfs:comment "Animals fail to respond to the concentration of a bioactive compound that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. A bioactive compound is a chemical found in small amounts in organisms or, synthetically produced, that has effects on biological processes in another organism." ;
rdfs:subClassOf obo:WBPhenotype_0001502 .
obo:CHEBI_64106 a rdfs:Class ;
rdfs:label "protein kinase agonist" ;
rdfs:comment "An agonist that selectively binds to and activates a protein kinase receptor." ;
rdfs:subClassOf obo:CHEBI_48705 .
obo:PATO_0000051 a rdfs:Class ;
rdfs:label "morphology" ;
rdfs:comment "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:GO_0140236 a rdfs:Class ;
rdfs:label "translation at presynapse" ;
rdfs:comment "Translation that occurs at the presynapse." ;
rdfs:subClassOf obo:GO_0006412 , obo:GO_0140241 .
obo:GO_0050000 a rdfs:Class ;
rdfs:label "chromosome localization" ;
rdfs:comment "Any process in which a chromosome is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051640 .
obo:WBls_0000808 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during 3-fold embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the 3-fold embryo life stage" ;
rdfs:subClassOf obo:WBls_0000805 .
obo:WBbt_0005431 a rdfs:Class ;
rdfs:label "phasmid left sensillum" ;
rdfs:comment "the left one in the pair of phasmid sensilla." ;
rdfs:subClassOf obo:WBbt_0005425 .
obo:CHEBI_75768 a rdfs:Class ;
rdfs:label "mammalian metabolite" ;
rdfs:comment "Any animal metabolite produced during a metabolic reaction in mammals." ;
rdfs:subClassOf obo:CHEBI_75767 .
obo:WBPhenotype_0000767 a rdfs:Class ;
rdfs:label "integrity of membranous organelles defective early emb" ;
rdfs:comment "Sparse or enlarged yolk granules." ;
rdfs:subClassOf obo:WBPhenotype_0000585 , obo:WBPhenotype_0001100 .
obo:CHEBI_51069 a rdfs:Class ;
rdfs:label "organic halide salt" ;
rdfs:subClassOf obo:CHEBI_24868 .
obo:GO_1903999 a rdfs:Class ;
rdfs:label "negative regulation of eating behavior" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903998 , obo:GO_2000252 .
obo:GO_1900194 a rdfs:Class ;
rdfs:label "negative regulation of oocyte maturation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900193 , obo:GO_1903430 , obo:GO_2000242 .
obo:GO_0003008 a rdfs:Class ;
rdfs:label "system process" ;
rdfs:comment "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0051784 a rdfs:Class ;
rdfs:label "negative regulation of nuclear division" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0051783 , obo:GO_0065007 .
obo:WBPhenotype_0004027 a rdfs:Class ;
rdfs:label "plate tap reflex variant" ;
rdfs:comment "Animals exhibit variations in their response to substrate vibration compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:WBPhenotype_0001951 a rdfs:Class ;
rdfs:label "pachytene region organization variant" ;
rdfs:comment "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001355 , obo:WBPhenotype_0001946 .
obo:CHEBI_33431 a rdfs:Class ;
rdfs:label "elemental chlorine" ;
rdfs:subClassOf obo:CHEBI_23117 , obo:CHEBI_33434 .
obo:GO_0099080 a rdfs:Class ;
rdfs:label "supramolecular complex" ;
rdfs:comment "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0000130 a rdfs:Class ;
rdfs:label "pheromone induced dauer formation enhanced" ;
rdfs:comment "Animals enter the dauer stage when exposed to lower concentrations or shorter exposure times of chemicals that induce dauer formation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000132 .
obo:CHEBI_16988 a rdfs:Class ;
rdfs:label "D-ribose" ;
rdfs:comment "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in D-glyceraldehyde." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33942 .
obo:CHEBI_78616 a rdfs:Class ;
rdfs:label "carbohydrates and carbohydrate derivatives" ;
rdfs:comment "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:WBPhenotype_0000377 a rdfs:Class ;
rdfs:label "canal lumen morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of the internal space of the excretory canal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000704 .
obo:WBPhenotype_0000044 a rdfs:Class ;
rdfs:label "egg size defective early emb" ;
rdfs:comment "Egg is smaller or larger compared to eggs of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0002407 .
obo:GO_1903423 a rdfs:Class ;
rdfs:label "positive regulation of synaptic vesicle recycling" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling." ;
rdfs:subClassOf obo:GO_0051050 , obo:GO_0065007 , obo:GO_1903421 .
obo:GO_1900075 a rdfs:Class ;
rdfs:label "positive regulation of neuromuscular synaptic transmission" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission." ;
rdfs:subClassOf obo:GO_0050806 , obo:GO_0065007 , obo:GO_1900073 .
obo:GO_0031468 a rdfs:Class ;
rdfs:label "nuclear membrane reassembly" ;
rdfs:comment "The reformation of the nuclear membranes following their breakdown in the context of a normal process." ;
rdfs:subClassOf obo:GO_0071709 , obo:GO_0071763 .
obo:GO_0140243 a rdfs:Class ;
rdfs:label "regulation of translation at synapse" ;
rdfs:comment "Any process that regulates translation occurring at the synapse." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:GO_0090664 a rdfs:Class ;
rdfs:label "response to high population density" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0032501 .
obo:WBPhenotype_0002351 a rdfs:Class ;
rdfs:label "hydrogen peroxide levels reduced" ;
rdfs:comment "Animals exhibit reductions in steady-state levels of hydrogen peroxide (H2O2) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002003 , obo:WBPhenotype_0002239 .
obo:GO_1905671 a rdfs:Class ;
rdfs:label "regulation of lysosome organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lysosome organization." ;
rdfs:subClassOf obo:GO_0044088 , obo:GO_0065007 .
obo:GO_0050776 a rdfs:Class ;
rdfs:label "regulation of immune response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0048583 , obo:GO_0065007 .
obo:CHEBI_50325 a rdfs:Class ;
rdfs:label "proteinogenic amino-acid side-chain group" ;
rdfs:comment "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid." ;
rdfs:subClassOf obo:CHEBI_33249 .
obo:CHEBI_22586 a rdfs:Class ;
rdfs:label "antioxidant" ;
rdfs:comment "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:WBPhenotype_0000698 a rdfs:Class ;
rdfs:label "vulvaless" ;
rdfs:comment "No vulval tissue is produced. In C. elegans, this is usually a result of all six vulval precursor cells adopting a tertiary fate." ;
rdfs:subClassOf obo:WBPhenotype_0000219 , obo:WBPhenotype_0002553 .
obo:WBbt_0007810 a rdfs:Class ;
rdfs:label "body muscle cell" ;
rdfs:comment "Any muscle cell that is not pharyngeal." ;
rdfs:subClassOf obo:WBbt_0003675 .
obo:WBPhenotype_0001623 a rdfs:Class ;
rdfs:label "male tail curling serotonin variant" ;
rdfs:comment "Any variation in the posture of the male tail after application of exogenous serotonin compared to control. In C. elegans, males respond with a tight ventral curling of the male tail in response to serotonin." ;
rdfs:subClassOf obo:WBPhenotype_0001232 .
obo:CHEBI_36914 a rdfs:Class ;
rdfs:label "inorganic ion" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_24870 .
obo:WBPhenotype_0001464 a rdfs:Class ;
rdfs:label "cGMP chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of cGMP." ;
rdfs:subClassOf obo:WBPhenotype_0001053 .
obo:GO_0006414 a rdfs:Class ;
rdfs:label "translational elongation" ;
rdfs:comment "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." ;
rdfs:subClassOf obo:GO_0009059 .
obo:WBPhenotype_0001436 a rdfs:Class ;
rdfs:label "nose touch hypersensitive" ;
rdfs:comment "Animals tend to initiate a response more often, compared to control, after nose-on collisions with an object. In C. elegans, animals initiate backwards movement in response to nose touch." ;
rdfs:subClassOf obo:WBPhenotype_0004026 .
obo:WBPhenotype_0000570 a rdfs:Class ;
rdfs:label "axon cisternae" ;
rdfs:comment "Axons of animals contain flattened membrane-bound compartments. In C. elegans, these cisternae-like structures are typically absent." ;
rdfs:subClassOf obo:WBPhenotype_0000568 .
obo:CHEBI_26469 a rdfs:Class ;
rdfs:label "quaternary nitrogen compound" ;
rdfs:comment "A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:WBPhenotype_0001559 a rdfs:Class ;
rdfs:label "dauer deirid sensillum variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC." ;
rdfs:subClassOf obo:WBPhenotype_0001535 , obo:WBPhenotype_0001556 .
obo:WBPhenotype_0010002 a rdfs:Class ;
rdfs:label "cell organization biogenesis variant" ;
rdfs:comment "Variations in the process(es) involved in the assembly and arrangement of cell structures compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002089 .
obo:WBPhenotype_0000618 a rdfs:Class ;
rdfs:label "coelomic system development variant" ;
rdfs:comment "Any variation in the progression of the coelomic system over time, from its formation to its mature state compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000530 .
obo:WBPhenotype_0000258 a rdfs:Class ;
rdfs:label "cell secretion variant" ;
rdfs:comment "Variations in the regulated release of substances by a cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:GO_1900182 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to nucleus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900180 , obo:GO_1903829 .
obo:CHEBI_76834 a rdfs:Class ;
rdfs:label "EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor" ;
rdfs:comment "An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*)." ;
rdfs:subClassOf obo:CHEBI_71300 .
obo:CHEBI_63161 a rdfs:Class ;
rdfs:label "glycosyl compound" ;
rdfs:comment "A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity." ;
rdfs:subClassOf obo:CHEBI_63299 .
obo:GO_0001764 a rdfs:Class ;
rdfs:label "neuron migration" ;
rdfs:comment "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." ;
rdfs:subClassOf obo:GO_0016477 .
obo:GO_1903531 a rdfs:Class ;
rdfs:label "negative regulation of secretion by cell" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0051048 , obo:GO_0065007 , obo:GO_1903530 .
obo:WBPhenotype_0002005 a rdfs:Class ;
rdfs:label "actomyosin cytoskeletal tension variant" ;
rdfs:comment "The tension of the cytoskeleton comprised of the actomyosin network differs from controls. This tension can be measured by laser-cutting of the actomyosin cytoskeleton and observing any differences the recoil velocity of cortex adjacent to the cut site." ;
rdfs:subClassOf obo:WBPhenotype_0001346 .
obo:WBPhenotype_0001784 a rdfs:Class ;
rdfs:label "obsolete lysosome homeostasis deficient" ;
rdfs:comment "OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes." .
obo:GO_0009786 a rdfs:Class ;
rdfs:label "regulation of asymmetric cell division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of asymmetric cell division." ;
rdfs:subClassOf obo:GO_0051302 , obo:GO_0065007 .
obo:GO_0098631 a rdfs:Class ;
rdfs:label "cell adhesion mediator activity" ;
rdfs:comment "The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0050839 .
obo:WBPhenotype_0001678 a rdfs:Class ;
rdfs:label "cuticle physiology variant" ;
rdfs:comment "Animals produce cuticles that vary in components such as proteins or carbohydrates, observed in control animals of the same developmental stage and raised under the same conditions." ;
rdfs:subClassOf obo:WBPhenotype_0001210 .
obo:CHEBI_29369 a rdfs:Class ;
rdfs:label "peroxy group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:GO_0033313 a rdfs:Class ;
rdfs:label "meiotic cell cycle checkpoint signaling" ;
rdfs:comment "A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage." ;
rdfs:subClassOf obo:GO_0000075 , obo:GO_1903046 .
obo:GO_0061673 a rdfs:Class ;
rdfs:label "mitotic spindle astral microtubule" ;
rdfs:comment "Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." ;
rdfs:subClassOf obo:GO_0000235 .
obo:GO_0030261 a rdfs:Class ;
rdfs:label "chromosome condensation" ;
rdfs:comment "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." ;
rdfs:subClassOf obo:GO_0051276 .
obo:CHEBI_33425 a rdfs:Class ;
rdfs:label "halogen oxoacid" ;
rdfs:subClassOf obo:CHEBI_24471 , obo:CHEBI_24833 .
obo:BFO_0000004 a rdfs:Class ;
rdfs:label "independent continuant"@en ;
rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:WBPhenotype_0000966 a rdfs:Class ;
rdfs:label "germline mortal" ;
rdfs:comment "Progressive decrease in brood size culminating, over generations, in the loss of reproductive ability and thus becoming effectively sterile." ;
rdfs:subClassOf obo:WBPhenotype_0000987 .
obo:GO_0034654 a rdfs:Class ;
rdfs:label "nucleobase-containing compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0006139 , obo:GO_0009058 .
obo:GO_0045824 a rdfs:Class ;
rdfs:label "negative regulation of innate immune response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response." ;
rdfs:subClassOf obo:GO_0002832 , obo:GO_0031348 , obo:GO_0032102 , obo:GO_0045088 , obo:GO_0050777 , obo:GO_0065007 .
obo:WBPhenotype_0002572 a rdfs:Class ;
rdfs:label "mitophagy abnormal"@en ;
rdfs:comment "Animals exhibit variations in mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000736 .
obo:GO_1990574 a rdfs:Class ;
rdfs:label "meiotic spindle astral microtubule" ;
rdfs:comment "Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." ;
rdfs:subClassOf obo:GO_0000235 .
obo:WBPhenotype_0001962 a rdfs:Class ;
rdfs:label "missing distal tip cells" ;
rdfs:comment "Animals produce less distal tip cells compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001656 , obo:WBPhenotype_0002174 .
obo:WBPhenotype_0000847 a rdfs:Class ;
rdfs:label "presynaptic component localization variant" ;
rdfs:comment "Animals display variations in the distribution of the constituents that make up the synaptic machinery such as those required for priming, docking or fusion of vesicles at the active zone, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001321 .
obo:GO_0007624 a rdfs:Class ;
rdfs:label "ultradian rhythm" ;
rdfs:comment "The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours." ;
rdfs:subClassOf obo:GO_0048511 .
obo:WBPhenotype_0001843 a rdfs:Class ;
rdfs:label "hormone metabolism variant" ;
rdfs:comment "Animals exhibit variations in any process that involves the degradation, biosynthesis or accumulation of hormones within the organism compared to control. Hormones are naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:GO_0051308 a rdfs:Class ;
rdfs:label "male meiosis chromosome separation" ;
rdfs:comment "The process in which paired chromosomes are physically detached from each other during male meiosis." ;
rdfs:subClassOf obo:GO_0007060 , obo:GO_0051304 , obo:GO_0051307 .
obo:CHEBI_17087 a rdfs:Class ;
rdfs:label "ketone" ;
rdfs:comment "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." ;
rdfs:subClassOf obo:CHEBI_36586 .
obo:CHEBI_24651 a rdfs:Class ;
rdfs:label "hydroxides" ;
rdfs:comment "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH−)." ;
rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_33608 , obo:CHEBI_37577 .
obo:GO_0032780 a rdfs:Class ;
rdfs:label "negative regulation of ATP-dependent activity" ;
rdfs:comment "Any process that stops or reduces the rate of an ATP-dependent activity." ;
rdfs:subClassOf obo:GO_0043462 , obo:GO_0044092 , obo:GO_0065007 .
obo:GO_0009295 a rdfs:Class ;
rdfs:label "nucleoid" ;
rdfs:comment "The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_39144 a rdfs:Class ;
rdfs:label "Lewis base" ;
rdfs:comment "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." ;
rdfs:subClassOf obo:CHEBI_17891 , obo:CHEBI_22695 .
obo:GO_2000382 a rdfs:Class ;
rdfs:label "positive regulation of mesoderm development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mesoderm development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_2000380 .
obo:WBPhenotype_0000462 a rdfs:Class ;
rdfs:label "paraquat hypersensitive" ;
rdfs:comment "Animals respond to paraquat at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000460 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000380 a rdfs:Class ;
rdfs:label "expulsion infrequent" ;
rdfs:comment "The final step of the defecation motor program does not occur at each cycle, but is activated occasionally. During this step in C. elegans specialized enteric muscles contract to expel the contents of the gut through the anus." ;
rdfs:subClassOf obo:WBPhenotype_0000996 .
obo:GO_0033120 a rdfs:Class ;
rdfs:label "positive regulation of RNA splicing" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of RNA splicing." ;
rdfs:subClassOf obo:GO_0010628 , obo:GO_0043484 , obo:GO_0065007 .
obo:GO_0031114 a rdfs:Class ;
rdfs:label "regulation of microtubule depolymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of microtubule depolymerization." ;
rdfs:subClassOf obo:GO_0031110 , obo:GO_0065007 , obo:GO_1901879 , obo:GO_1902903 .
obo:CHEBI_35498 a rdfs:Class ;
rdfs:label "diuretic" ;
rdfs:comment "An agent that promotes the excretion of urine through its effects on kidney function." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:WBPhenotype_0002201 a rdfs:Class ;
rdfs:label "apoptotic DNA degradation defective" ;
rdfs:comment "Dying animals cells exhibit defects in the fragmentation of chromosomal DNA into oligonucleosomal-length fragments compared to control animals. This process can be monitored by the quantity and quality of TUNEL (TdT-mediated dUTP nick end labeling)-positive nuclei." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:GO_1903463 a rdfs:Class ;
rdfs:label "regulation of mitotic cell cycle DNA replication" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0033262 , obo:GO_0065007 .
obo:WBPhenotype_0001079 a rdfs:Class ;
rdfs:label "cytoplasmic dynamics defective early emb" ;
rdfs:comment "Cytoplasmic movements are atypical." ;
rdfs:subClassOf obo:WBPhenotype_0000360 , obo:WBPhenotype_0000769 .
obo:WBbt_0007833 a rdfs:Class ;
rdfs:label "organism" ;
rdfs:comment "Anatomical structure that is an individual member of a species and consists of more than one cell." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:WBPhenotype_0002640 a rdfs:Class ;
rdfs:label "cuticle integrity decreased"@en ;
rdfs:comment "The physical strength or integrity of the cuticle is decreased compared to that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001211 .
obo:GO_0032350 a rdfs:Class ;
rdfs:label "regulation of hormone metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ;
rdfs:subClassOf obo:GO_0010817 , obo:GO_0019222 , obo:GO_0065007 .
obo:GO_0006403 a rdfs:Class ;
rdfs:label "RNA localization" ;
rdfs:comment "A process in which RNA is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0033036 .
obo:CHEBI_30776 a rdfs:Class ;
rdfs:label "hexanoic acid" ;
rdfs:comment "A C6, straight-chain saturated fatty acid." ;
rdfs:subClassOf obo:CHEBI_39418 , obo:CHEBI_59554 .
obo:GO_1902850 a rdfs:Class ;
rdfs:label "microtubule cytoskeleton organization involved in mitosis" ;
rdfs:comment "Any microtubule cytoskeleton organization that is involved in mitosis." ;
rdfs:subClassOf obo:GO_0000226 , obo:GO_1903047 .
obo:WBPhenotype_0001352 a rdfs:Class ;
rdfs:label "endoplasmic reticulum metabolism variant" ;
rdfs:comment "Variations in the chemical reactions and pathways of the endoplasmic reticulum compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001283 .
obo:WBPhenotype_0001083 a rdfs:Class ;
rdfs:label "multiple cytoplasmic cavities early emb" ;
rdfs:comment "Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis." ;
rdfs:subClassOf obo:WBPhenotype_0001081 .
obo:WBPhenotype_0002327 a rdfs:Class ;
rdfs:label "velocity of movement increased" ;
rdfs:comment "Animals exhibit an increase in the net velocity of an animal" ;
rdfs:subClassOf obo:WBPhenotype_0004025 .
obo:GO_0044089 a rdfs:Class ;
rdfs:label "positive regulation of cellular component biogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." ;
rdfs:subClassOf obo:GO_0044087 , obo:GO_0048522 , obo:GO_0065007 .
obo:GO_0044419 a rdfs:Class ;
rdfs:label "biological process involved in interspecies interaction between organisms" ;
rdfs:comment "Any process evolved to enable an interaction with an organism of a different species." ;
rdfs:subClassOf obo:GO_0008150 .
obo:BFO_0000015 a rdfs:Class ;
rdfs:label "process"@en ;
rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
rdfs:subClassOf obo:BFO_0000003 .
obo:GO_0045665 a rdfs:Class ;
rdfs:label "negative regulation of neuron differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0045664 , obo:GO_0065007 .
obo:CHEBI_36315 a rdfs:Class ;
rdfs:label "glycerophosphoinositol" ;
rdfs:comment "Any glycerophospholipid having the polar alcohol inositol esterified to the phosphate group at the sn-3 position of the glycerol backbone." ;
rdfs:subClassOf obo:CHEBI_37739 .
obo:GO_0097485 a rdfs:Class ;
rdfs:label "neuron projection guidance" ;
rdfs:comment "The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues." ;
rdfs:subClassOf obo:GO_0031175 .
obo:GO_1903744 a rdfs:Class ;
rdfs:label "positive regulation of anterograde synaptic vesicle transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901610 , obo:GO_1902805 , obo:GO_1903742 .
obo:PATO_0000044 a rdfs:Class ;
rdfs:label "frequency" ;
rdfs:comment "A physical quality which inheres in a bearer by virtue of the number of the bearer's repetitive actions in a particular time." ;
rdfs:subClassOf obo:PATO_0050000 .
obo:GO_1901889 a rdfs:Class ;
rdfs:label "negative regulation of cell junction assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1901888 .
obo:WBbt_0005775 a rdfs:Class ;
rdfs:label "excretory canal" ;
rdfs:comment "Four processes (canals) of the excretory canal cell each contain a central collecting lumen which feeds to a central lumenal canal in the cell body; the central canal forms a specialized membrane to release fluids into the excretory duct. These five canals form a continuous H-shaped channel which extends almost the full length of the body, generally in contact with the lateral hypodermis and the pseudocoelom." ;
rdfs:subClassOf obo:WBbt_0005732 .
obo:CHEBI_50949 a rdfs:Class ;
rdfs:label "serotonin uptake inhibitor" ;
rdfs:comment "A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent." ;
rdfs:subClassOf obo:CHEBI_48278 .
obo:WBPhenotype_0000334 a rdfs:Class ;
rdfs:label "isthmus corpus slippery" ;
rdfs:comment "Failure of muscle contractions in the corpus and isthmus to trap and transport bacteria posteriorly in the pharynx." ;
rdfs:subClassOf obo:WBPhenotype_0000335 .
obo:WBPhenotype_0000740 a rdfs:Class ;
rdfs:label "cell cycle variant" ;
rdfs:comment "Cells of the animals exhibit variations in the initiation, progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:GO_1901525 a rdfs:Class ;
rdfs:label "negative regulation of mitophagy" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy." ;
rdfs:subClassOf obo:GO_0016242 , obo:GO_0065007 , obo:GO_1901524 , obo:GO_1903147 .
obo:CHEBI_60004 a rdfs:Class ;
rdfs:label "mixture" ;
rdfs:comment "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." ;
rdfs:subClassOf obo:CHEBI_59999 .
obo:WBPhenotype_0000069 a rdfs:Class ;
rdfs:label "progeny variant" ;
rdfs:comment "Any variation in the progression of the progeny of an animal at any time from its fertilization to adulthood compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000531 .
obo:WBPhenotype_0000669 a rdfs:Class ;
rdfs:label "sex muscle development variant" ;
rdfs:comment "Variations in the progression of the muscles of the adult reproductive system over time form their initial formation to their mature structure compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000624 , obo:WBPhenotype_0000860 .
obo:CHEBI_26979 a rdfs:Class ;
rdfs:label "organic heterotricyclic compound" ;
rdfs:comment "An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms." ;
rdfs:subClassOf obo:CHEBI_36688 , obo:CHEBI_38166 , obo:CHEBI_51959 .
obo:GO_1903530 a rdfs:Class ;
rdfs:label "regulation of secretion by cell" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of secretion by cell." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0051046 , obo:GO_0065007 .
obo:PATO_0001570 a rdfs:Class ;
rdfs:label "having decreased processual parts" ;
rdfs:comment "A quality of a process inhering in a bearer by virtue of the bearer's having fewer processual parts." ;
rdfs:subClassOf obo:PATO_0001564 .
obo:WBbt_0005656 a rdfs:Class ;
rdfs:label "retrovesicular ganglion" ;
rdfs:comment "Ganglion that lies at the anterior limit of the ventral nerve cord, near the ventral ganglion and nerve ring in the head posterior to the excretory pore. It is open and continuous with the region containing the motoneurons of the ventral cord. In the early L1 this ganglion holds 12 neuron cell bodies plus one neuroblast (Sulston and Horvitz, 1977; White et al., 1986). In the adult animal, the ganglion holds 20 neuron cell bodies." ;
rdfs:subClassOf obo:WBbt_0005332 .
obo:WBPhenotype_0000300 a rdfs:Class ;
rdfs:label "amphid sheath cell morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or composition of the amphid sensillum cell that ensheathes the dendrite tips of channel neurons and wing cell dedritic processes, from that observed in control animals. Sheath cells in C.elegans have highly invaginated and vesiculated surfaces, which provide a specialized environment for the dendritic structures." ;
rdfs:subClassOf obo:WBPhenotype_0000972 , obo:WBPhenotype_0001527 .
obo:CHEBI_51372 a rdfs:Class ;
rdfs:label "neuromuscular agent" ;
rdfs:comment "A drug used for its actions on skeletal muscle." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:CHEBI_48357 a rdfs:Class ;
rdfs:label "aprotic solvent" ;
rdfs:subClassOf obo:CHEBI_46787 .
obo:PATO_0000014 a rdfs:Class ;
rdfs:label "color" ;
rdfs:comment "A composite chromatic quality composed of hue, saturation and intensity parts." ;
rdfs:subClassOf obo:PATO_0000051 , obo:PATO_0001300 .
obo:CHEBI_36841 a rdfs:Class ;
rdfs:label "11-hydroxy steroid" ;
rdfs:subClassOf obo:CHEBI_35350 .
obo:WBPhenotype_0001377 a rdfs:Class ;
rdfs:label "break induced focus formation variant" ;
rdfs:comment "Variations in the generation of foci that mark crossover recombination events, compared to control. These foci mark the boundary of asymmetric synaptonemal complex disassembly." ;
rdfs:subClassOf obo:WBPhenotype_0001256 , obo:WBPhenotype_0001324 .
obo:GO_0043414 a rdfs:Class ;
rdfs:label "macromolecule methylation" ;
rdfs:comment "The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule." ;
rdfs:subClassOf obo:GO_0032259 , obo:GO_0043412 .
obo:CHEBI_76725 a rdfs:Class ;
rdfs:label "EC 1.* (oxidoreductase) inhibitor" ;
rdfs:comment "An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*)." ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:WBPhenotype_0001694 a rdfs:Class ;
rdfs:label "spermatogenesis to oogenesis switch defective" ;
rdfs:comment "Hermaphrodites continue to produce sperm past the time at which the transition to oogenesis normally occurs. Thus, germ cells that would normally become oocytes are transformed into sperm instead." ;
rdfs:subClassOf obo:WBPhenotype_0001572 .
obo:CHEBI_50846 a rdfs:Class ;
rdfs:label "immunomodulator" ;
rdfs:comment "Biologically active substance whose activity affects or plays a role in the functioning of the immune system." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_24432 .
obo:WBPhenotype_0001522 a rdfs:Class ;
rdfs:label "spicules protrude" ;
rdfs:comment "The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) constitutively extend into the external environment through the cloacal opening. In C. elegans males there are two copulatory spicules." ;
rdfs:subClassOf obo:WBPhenotype_0000908 .
obo:GO_1901992 a rdfs:Class ;
rdfs:label "positive regulation of mitotic cell cycle phase transition" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition." ;
rdfs:subClassOf obo:GO_0045931 , obo:GO_0065007 , obo:GO_1901989 , obo:GO_1901990 .
obo:WBPhenotype_0002356 a rdfs:Class ;
rdfs:label "sickened by nonpathogenic bacteria" ;
rdfs:comment "Animals are negatively affected by bacteria that is nonpathogenic to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002545 .
obo:WBPhenotype_0001507 a rdfs:Class ;
rdfs:label "Bacillus thuringiensis toxin resistant" ;
rdfs:comment "Animals fail to be affected by toxins produced by Bacillus thuringiensis (Bt toxins) in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 .
obo:CHEBI_38825 a rdfs:Class ;
rdfs:label "tetrafluoromethane" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_38824 , obo:CHEBI_39281 .
obo:GO_0010212 a rdfs:Class ;
rdfs:label "response to ionizing radiation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays." ;
rdfs:subClassOf obo:GO_0009314 .
obo:WBPhenotype_0001191 a rdfs:Class ;
rdfs:label "pharyngeal muscle physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for muscles in the pharynx to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000990 , obo:WBPhenotype_0001190 .
obo:WBPhenotype_0001403 a rdfs:Class ;
rdfs:label "antibody subcellular localization variant" ;
rdfs:comment "Any variation in the placement of a protein, as detected by antibody staining, within in a cell or cellular compartment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000424 .
obo:WBPhenotype_0000438 a rdfs:Class ;
rdfs:label "retarded heterochronic variations" ;
rdfs:comment "Variations that result in the deceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000033 .
obo:GO_0090306 a rdfs:Class ;
rdfs:label "meiotic spindle assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis." ;
rdfs:subClassOf obo:GO_0000212 , obo:GO_0051225 .
obo:GO_0071028 a rdfs:Class ;
rdfs:label "nuclear mRNA surveillance" ;
rdfs:comment "A process that identifies and degrades defective or aberrant mRNAs within the nucleus." ;
rdfs:subClassOf obo:GO_0000956 , obo:GO_0071027 .
obo:GO_0009967 a rdfs:Class ;
rdfs:label "positive regulation of signal transduction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of signal transduction." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0010647 , obo:GO_0023056 , obo:GO_0048584 , obo:GO_0065007 .
obo:WBPhenotype_0000349 a rdfs:Class ;
rdfs:label "flaccid" ;
rdfs:comment "A semi-paralysed body phenotype in which muscle tone is lost and the animal fails to actively control its body shape (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000001 .
obo:CHEBI_139592 a rdfs:Class ;
rdfs:label "tertiary alpha-hydroxy ketone" ;
rdfs:comment "An α-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups." ;
rdfs:subClassOf obo:CHEBI_139588 , obo:CHEBI_26878 .
obo:WBPhenotype_0000478 a rdfs:Class ;
rdfs:label "isothermal tracking behavior variant" ;
rdfs:comment "Variations in the ability of an animal to remain within a defined temperature. In C. elegans, animals tend to track and stay within a temperature that is most closely related to their cultivation temperature." ;
rdfs:subClassOf obo:WBPhenotype_0002513 .
obo:WBPhenotype_0002335 a rdfs:Class ;
rdfs:label "path curvature variant" ;
rdfs:comment "Animals exhibit variations in the extent to which the overall path of movement is curved, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0004017 .
obo:WBPhenotype_0000838 a rdfs:Class ;
rdfs:label "male gonadal lineage variant" ;
rdfs:comment "The descendants of a gonadal precursor cell exhibit altered developmental programs in the male compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000809 , obo:WBPhenotype_0000836 .
obo:GO_0045927 a rdfs:Class ;
rdfs:label "positive regulation of growth" ;
rdfs:comment "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." ;
rdfs:subClassOf obo:GO_0040008 , obo:GO_0048518 , obo:GO_0065007 .
obo:CHEBI_39279 a rdfs:Class ;
rdfs:label "halomethane" ;
rdfs:comment "A haloalkane that is methane in which one (or more) of the hydrogens have been replaced by a halogen atom/halogen atoms." ;
rdfs:subClassOf obo:CHEBI_24469 , obo:CHEBI_64708 .
obo:GO_0051334 a rdfs:Class ;
rdfs:label "meiosis I nuclear membrane reassembly" ;
rdfs:comment "The reformation of the nuclear membranes during meiosis I." ;
rdfs:subClassOf obo:GO_0031468 , obo:GO_0051333 .
obo:WBPhenotype_0001265 a rdfs:Class ;
rdfs:label "head movement variant" ;
rdfs:comment "The anterior portion of the animal exhibits variations in its movement compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001699 .
obo:CHEBI_35131 a rdfs:Class ;
rdfs:label "aldose phosphate" ;
rdfs:subClassOf obo:CHEBI_33447 .
obo:WBPhenotype_0001947 a rdfs:Class ;
rdfs:label "diplotene progression during oogenesis variant" ;
rdfs:comment "Developing oocytes show defects in their entry, progression through or exit from the diplotene stage compared to control animals. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." ;
rdfs:subClassOf obo:WBPhenotype_0001824 .
obo:WBPhenotype_0002099 a rdfs:Class ;
rdfs:label "lysosome-related organelle localization variant" ;
rdfs:comment "Any variation in the subcellular localization of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002098 .
obo:WBPhenotype_0001587 a rdfs:Class ;
rdfs:label "actin organization biogenesis phenotype" ;
rdfs:comment "Animals exhibit variations in the formation and/or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001345 .
obo:WBPhenotype_0002632 a rdfs:Class ;
rdfs:label "chromatin accessibility abnormal"@en ;
rdfs:comment "Animals exhibit cells with an abnormal degree of chromatin accessibility, compared to controls, detected using techniques such as ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing)." ;
rdfs:subClassOf obo:WBPhenotype_0001348 .
obo:CHEBI_17478 a rdfs:Class ;
rdfs:label "aldehyde" ;
rdfs:comment "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group." ;
rdfs:subClassOf obo:CHEBI_36586 .
obo:CHEBI_48377 a rdfs:Class ;
rdfs:label "imidic acid" ;
rdfs:comment "Compounds derived from oxoacids RkE(=O)l(OH)m (l ≠ 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH)." ;
rdfs:subClassOf obo:CHEBI_33241 , obo:CHEBI_51143 .
obo:CHEBI_138675 a rdfs:Class ;
rdfs:label "gas molecular entity" ;
rdfs:comment "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0°C and 100 kPa)." ;
rdfs:subClassOf obo:CHEBI_33579 .
obo:GO_0097014 a rdfs:Class ;
rdfs:label "ciliary plasm" ;
rdfs:comment "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." ;
rdfs:subClassOf obo:GO_0005737 .
obo:GO_0032880 a rdfs:Class ;
rdfs:label "regulation of protein localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0032879 , obo:GO_0065007 .
obo:GO_0032200 a rdfs:Class ;
rdfs:label "telomere organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins." ;
rdfs:subClassOf obo:GO_0051276 .
obo:GO_0006810 a rdfs:Class ;
rdfs:label "transport" ;
rdfs:comment "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." ;
rdfs:subClassOf obo:GO_0051234 .
obo:WBPhenotype_0001656 a rdfs:Class ;
rdfs:label "distal tip cell development variant" ;
rdfs:comment "Any variation in the progression of the leader cell that guides and shapes the outgrowth of the gonad while crawling along the body wall to force the germline to extend into a long tubular shape over time from its formation to its mature structure compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000399 .
obo:WBPhenotype_0000107 a rdfs:Class ;
rdfs:label "inhibition of ovulation variant" ;
rdfs:comment "Any variation that alters the control mechanisms that inhibit oocyte maturation and release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000666 .
obo:GO_0048513 a rdfs:Class ;
rdfs:label "animal organ development" ;
rdfs:comment "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0048581 a rdfs:Class ;
rdfs:label "negative regulation of post-embryonic development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ;
rdfs:subClassOf obo:GO_0048580 , obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 .
obo:CHEBI_26830 a rdfs:Class ;
rdfs:label "sulfonium compound" ;
rdfs:subClassOf obo:CHEBI_26835 .
obo:WBPhenotype_0001097 a rdfs:Class ;
rdfs:label "premature spermatocyte germ cell differentiation" ;
rdfs:comment "Unspecialized male germ cells (spermatocytes) prematurely acquire the specialized properties of functional sperm." ;
rdfs:subClassOf obo:WBPhenotype_0000670 .
obo:PATO_0001926 a rdfs:Class ;
rdfs:label "increased fluorescence" ;
rdfs:comment "A fluorescence which is higher than normal." ;
rdfs:subClassOf obo:PATO_0001290 , obo:PATO_0002305 .
obo:CHEBI_33281 a rdfs:Class ;
rdfs:label "antimicrobial agent" ;
rdfs:comment "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:GO_0010793 a rdfs:Class ;
rdfs:label "regulation of mRNA export from nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm." ;
rdfs:subClassOf obo:GO_0046831 , obo:GO_0065007 , obo:GO_2000197 .
obo:WBbt_0006750 a rdfs:Class ;
rdfs:label "dorsal nerve cord" ;
rdfs:comment "a bundle of nerve processes that runs along the dorsal mid-line of the animal." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:GO_0010628 a rdfs:Class ;
rdfs:label "positive regulation of gene expression" ;
rdfs:comment "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0010557 , obo:GO_0065007 .
obo:WBPhenotype_0001280 a rdfs:Class ;
rdfs:label "transgene expression reduced hermaphrodite" ;
rdfs:comment "Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the hermaphrodite, that has been introduced into the organism compared to its expression in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001278 .
obo:GO_0010324 a rdfs:Class ;
rdfs:label "membrane invagination" ;
rdfs:comment "The infolding of a membrane." ;
rdfs:subClassOf obo:GO_0061024 .
obo:GO_0071479 a rdfs:Class ;
rdfs:label "cellular response to ionizing radiation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays." ;
rdfs:subClassOf obo:GO_0010212 , obo:GO_0071478 .
obo:CHEBI_57925 a rdfs:Class ;
rdfs:label "glutathionate(1-)" ;
rdfs:comment "A peptide anion obtained by deprotonation of both carboxy groups and protonation of the glutamyl amino group of glutathione; major species at pH 7.3." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_60334 .
obo:CHEBI_46640 a rdfs:Class ;
rdfs:label "diketone" ;
rdfs:comment "A compound that contains two ketone functionalities." ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:GO_0051239 a rdfs:Class ;
rdfs:label "regulation of multicellular organismal process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:WBPhenotype_0001593 a rdfs:Class ;
rdfs:label "transgene silencing variant" ;
rdfs:comment "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control. In C. elegans this silencing occurs only in the germline." ;
rdfs:subClassOf obo:WBPhenotype_0002063 .
obo:GO_0009453 a rdfs:Class ;
rdfs:label "energy taxis" ;
rdfs:comment "The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates." ;
rdfs:subClassOf obo:GO_0042330 .
obo:WBPhenotype_0001362 a rdfs:Class ;
rdfs:label "chromosome condensation failure" ;
rdfs:comment "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis in eukaryotic cells is abolished." ;
rdfs:subClassOf obo:WBPhenotype_0001361 .
obo:WBPhenotype_0000756 a rdfs:Class ;
rdfs:label "L2 L3 molt defect" ;
rdfs:comment "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L2 to L3 transition." ;
rdfs:subClassOf obo:WBPhenotype_0000638 .
obo:GO_0062033 a rdfs:Class ;
rdfs:label "positive regulation of mitotic sister chromatid segregation" ;
rdfs:comment "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." ;
rdfs:subClassOf obo:GO_0033047 , obo:GO_0051984 , obo:GO_0065007 , obo:GO_2001252 .
obo:WBPhenotype_0002289 a rdfs:Class ;
rdfs:label "tail bend angle increased" ;
rdfs:comment "Animals exhibit an increase in the extent of the maximum flex of the most posterior portion of the animal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002288 .
obo:GO_1901046 a rdfs:Class ;
rdfs:label "positive regulation of egg-laying behavior" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of oviposition." ;
rdfs:subClassOf obo:GO_0046662 , obo:GO_0048520 , obo:GO_0065007 , obo:GO_2000243 .
obo:WBPhenotype_0001330 a rdfs:Class ;
rdfs:label "egg laying event infrequent" ;
rdfs:comment "The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate is reduced compared to that observed in control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000006 , obo:WBPhenotype_0000272 .
obo:GO_0045835 a rdfs:Class ;
rdfs:label "negative regulation of meiotic nuclear division" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0040020 , obo:GO_0051447 , obo:GO_0051784 , obo:GO_0065007 .
obo:CHEBI_32564 a rdfs:Class ;
rdfs:label "lysinium(1+)" ;
rdfs:comment "An α-amino-acid cation that is the conjugate acid of lysine, having two cationic amino groups and an anionic carboxy group." ;
rdfs:subClassOf obo:CHEBI_33719 .
obo:WBPhenotype_0001619 a rdfs:Class ;
rdfs:label "isoflurane resistant" ;
rdfs:comment "Animals fail to respond to the concentration of the volatile anesthetic isoflurane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000009 , obo:WBPhenotype_0001502 .
obo:CHEBI_76924 a rdfs:Class ;
rdfs:label "plant metabolite" ;
rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." ;
rdfs:subClassOf obo:CHEBI_75763 .
obo:WBPhenotype_0000942 a rdfs:Class ;
rdfs:label "accessory cell development variant" ;
rdfs:comment "Any variation in the progression of an accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. An accessory cell supports sensory neurons." ;
rdfs:subClassOf obo:WBPhenotype_0000623 .
obo:WBPhenotype_0001429 a rdfs:Class ;
rdfs:label "granules cytoplasm" ;
rdfs:comment "Animals accumulate an excess of vesicle-like structures in cells." ;
rdfs:subClassOf obo:WBPhenotype_0001427 .
obo:CHEBI_25107 a rdfs:Class ;
rdfs:label "magnesium atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_22313 .
obo:WBPhenotype_0002241 a rdfs:Class ;
rdfs:label "feeding reduced" ;
rdfs:comment "Animals consume less food than control animals" ;
rdfs:subClassOf obo:WBPhenotype_0000659 .
obo:WBPhenotype_0001634 a rdfs:Class ;
rdfs:label "organism electrophilic stress hypersensitive" ;
rdfs:comment "Animals respond to compounds that elicit electrophilic stress at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:GO_0140392 a rdfs:Class ;
rdfs:label "extracellular protein-containing complex" ;
rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together outside a cell." ;
rdfs:subClassOf obo:GO_0032991 .
obo:CHEBI_25367 a rdfs:Class ;
rdfs:label "molecule" ;
rdfs:comment "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_36357 .
obo:GO_0035967 a rdfs:Class ;
rdfs:label "cellular response to topologically incorrect protein" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." ;
rdfs:subClassOf obo:GO_0033554 , obo:GO_0035966 .
obo:WBPhenotype_0000099 a rdfs:Class ;
rdfs:label "P lineages variant" ;
rdfs:comment "The descendants of any of the P precursor cells exhibit variations in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000825 .
obo:CHEBI_50314 a rdfs:Class ;
rdfs:label "fluoronium" ;
rdfs:subClassOf obo:CHEBI_50313 .
obo:WBPhenotype_0001821 a rdfs:Class ;
rdfs:label "non bordering" ;
rdfs:comment "Animals do not accumulate at the thickest part of the bacterial lawn. Animals do not preferentially deplete bacterial food at the thicker parts of the lawn." ;
rdfs:subClassOf obo:WBPhenotype_0000662 , obo:WBPhenotype_0001291 .
obo:GO_0043244 a rdfs:Class ;
rdfs:label "regulation of protein-containing complex disassembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:WBPhenotype_0001544 a rdfs:Class ;
rdfs:label "dauer sensory response variant" ;
rdfs:comment "Variations in the state or activity of a dauer stage organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001001 .
obo:CHEBI_33252 a rdfs:Class ;
rdfs:label "atomic nucleus" ;
rdfs:comment "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." ;
rdfs:subClassOf obo:CHEBI_36347 .
obo:GO_0050922 a rdfs:Class ;
rdfs:label "negative regulation of chemotaxis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ;
rdfs:subClassOf obo:GO_0032102 , obo:GO_0040013 , obo:GO_0050920 , obo:GO_0065007 .
obo:GO_0000819 a rdfs:Class ;
rdfs:label "sister chromatid segregation" ;
rdfs:comment "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." ;
rdfs:subClassOf obo:GO_0051276 , obo:GO_0098813 .
obo:CHEBI_25016 a rdfs:Class ;
rdfs:label "lead atom" ;
rdfs:subClassOf obo:CHEBI_233500 , obo:CHEBI_33306 .
obo:WBPhenotype_0000762 a rdfs:Class ;
rdfs:label "spindle position defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ;
rdfs:subClassOf obo:WBPhenotype_0000761 , obo:WBPhenotype_0002416 .
obo:GO_0141124 a rdfs:Class ;
rdfs:label "intracellular signaling cassette" ;
rdfs:comment "An intracellular signaling module that is part of larger signaling pathways that can be initiated either intracellularly or by cell surface receptors. Intracellular signaling cassettes are discrete signaling units that are often shared by multiple signaling pathways." ;
rdfs:subClassOf obo:GO_0035556 .
obo:WBPhenotype_0001061 a rdfs:Class ;
rdfs:label "AWA odorant chemotaxis defective" ;
rdfs:comment "In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWA compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001438 .
obo:WBPhenotype_0002166 a rdfs:Class ;
rdfs:label "muscle membrane potential variant" ;
rdfs:comment "The difference in electrical potential between the interior and the exterior of the muscle cell either in the resting state or during evoked stimulation differs from controls." ;
rdfs:subClassOf obo:WBPhenotype_0000990 , obo:WBPhenotype_0001965 .
obo:WBPhenotype_0000823 a rdfs:Class ;
rdfs:label "germline proliferation variant" ;
rdfs:comment "Nuclear divisions in the germ line are either expanded are reduced compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000812 .
obo:WBbt_0006926 a rdfs:Class ;
rdfs:label "deirid sensillum" ;
rdfs:comment "LINKOUT::WORMATLAS::" ;
rdfs:subClassOf obo:WBbt_0006929 .
obo:GO_0051446 a rdfs:Class ;
rdfs:label "positive regulation of meiotic cell cycle" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0045787 , obo:GO_0051445 , obo:GO_0065007 , obo:GO_2000243 .
obo:GO_0060278 a rdfs:Class ;
rdfs:label "regulation of ovulation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 , obo:GO_2000241 .
obo:WBPhenotype_0001672 a rdfs:Class ;
rdfs:label "commisure growth variant" ;
rdfs:comment "Animals exhibit variations in the extension of the part of the axon that forms a bridge between body regions, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001224 .
obo:CHEBI_25094 a rdfs:Class ;
rdfs:label "lysine" ;
rdfs:comment "A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6." ;
rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 , obo:CHEBI_35987 .
obo:CHEBI_33745 a rdfs:Class ;
rdfs:label "copper group molecular entity" ;
rdfs:subClassOf obo:CHEBI_33676 .
obo:GO_1903429 a rdfs:Class ;
rdfs:label "regulation of cell maturation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell maturation." ;
rdfs:subClassOf obo:GO_0060284 , obo:GO_0065007 .
obo:WBPhenotype_0001566 a rdfs:Class ;
rdfs:label "ventral enclosure variant" ;
rdfs:comment "Any variation in the process that regulates the migration of ventral epidermal cells toward the ventral midline (to encase underlying cells in an epithelial monolayer) in developing embryos compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:CHEBI_50127 a rdfs:Class ;
rdfs:label "trifluoromethyl group" ;
rdfs:subClassOf obo:CHEBI_50491 .
obo:WBPhenotype_0000854 a rdfs:Class ;
rdfs:label "intraflagellar transport defective" ;
rdfs:comment "Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is disrupted." ;
rdfs:subClassOf obo:WBPhenotype_0000853 .
obo:GO_1902339 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic process involved in morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904747 .
obo:GO_1900116 a rdfs:Class ;
rdfs:label "extracellular negative regulation of signal transduction" ;
rdfs:comment "Any negative regulation of signal transduction that takes place in extracellular region." ;
rdfs:subClassOf obo:GO_0009968 , obo:GO_1900115 .
obo:CHEBI_35471 a rdfs:Class ;
rdfs:label "psychotropic drug" ;
rdfs:comment "A loosely defined grouping of drugs that have effects on psychological function." ;
rdfs:subClassOf obo:CHEBI_35470 .
obo:GO_0032097 a rdfs:Class ;
rdfs:label "positive regulation of response to food" ;
rdfs:comment "Any process that activates, maintains, or increases the rate of a response to a food stimulus." ;
rdfs:subClassOf obo:GO_0032095 , obo:GO_0032109 , obo:GO_0065007 .
obo:GO_0009896 a rdfs:Class ;
rdfs:label "positive regulation of catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0009894 , obo:GO_0065007 .
obo:WBPhenotype_0001761 a rdfs:Class ;
rdfs:label "axon midline crossing variant" ;
rdfs:comment "Regulated ventral midline crossing by axons vary either in the frequency of crossing events or the maintenance through development of process positions compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000384 .
obo:WBPhenotype_0001287 a rdfs:Class ;
rdfs:label "suppressed pharyngeal pumping defective" ;
rdfs:comment "Animals do not exhibit a decrease in pumping rate when treated with specific compounds (such as pheromones) as is observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001006 .
obo:PATO_0001477 a rdfs:Class ;
rdfs:label "retracted" ;
rdfs:comment "A positional quality inhering in a bearer by virtue of the bearer's being drawn in or pulled back from any given point." ;
rdfs:subClassOf obo:PATO_0000140 .
obo:WBPhenotype_0000860 a rdfs:Class ;
rdfs:label "nonstriated muscle development variant" ;
rdfs:comment "Variations in the progression of muscle cells that lack transverse striations in its constituent fibers and are almost always involuntary, over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000622 .
obo:WBPhenotype_0002662 a rdfs:Class ;
rdfs:label "transgene silencing increased"@en ;
rdfs:comment "Animals exhibit an increase in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001593 .
obo:CHEBI_33241 a rdfs:Class ;
rdfs:label "oxoacid derivative" ;
rdfs:subClassOf obo:CHEBI_37577 .
obo:CHEBI_32457 a rdfs:Class ;
rdfs:label "cysteinate(2-)" ;
rdfs:subClassOf obo:CHEBI_33558 .
obo:CHEBI_35221 a rdfs:Class ;
rdfs:label "antimetabolite" ;
rdfs:comment "A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization." ;
rdfs:subClassOf obo:CHEBI_52206 .
obo:GO_1905629 a rdfs:Class ;
rdfs:label "positive regulation of serotonin biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0065007 , obo:GO_1905627 .
obo:WBPhenotype_0002426 a rdfs:Class ;
rdfs:label "protein aggregation induced reduction of life span" ;
rdfs:comment "The duration of viability in the adult phase of the life-cycle is lowered in response to the aggregation of proteins." ;
rdfs:subClassOf obo:WBPhenotype_0002425 .
obo:WBPhenotype_0002613 a rdfs:Class ;
rdfs:label "meiotic cytoplasmic streaming phenotype"@en ;
rdfs:comment "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is abnormal compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002612 .
obo:WBPhenotype_0002173 a rdfs:Class ;
rdfs:label "cell number variant" ;
rdfs:comment "Animals exhibit variations in the number of cells that make up the organism compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000531 .
obo:GO_0097060 a rdfs:Class ;
rdfs:label "synaptic membrane" ;
rdfs:comment "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." ;
rdfs:subClassOf obo:GO_0098590 .
obo:CHEBI_33916 a rdfs:Class ;
rdfs:label "aldopentose" ;
rdfs:comment "A pentose with a (potential) aldehyde group at one end." ;
rdfs:subClassOf obo:CHEBI_15693 , obo:CHEBI_25901 .
obo:WBPhenotype_0000600 a rdfs:Class ;
rdfs:label "epithelial system morphology variant" ;
rdfs:comment "Variations in the form, composition or structure of the epithelial system that serves to protect the organism from the external environment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000534 .
obo:WBPhenotype_0000051 a rdfs:Class ;
rdfs:label "embryonic terminal arrest variable emb" ;
rdfs:comment "The developmental program does not continue past embryogenesis; stage of arrest is not consistent from animal to animal." ;
rdfs:subClassOf obo:WBPhenotype_0000063 , obo:WBPhenotype_0000749 .
obo:GO_0044062 a rdfs:Class ;
rdfs:label "regulation of excretion" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." ;
rdfs:subClassOf obo:GO_0044057 , obo:GO_0051046 , obo:GO_0065007 .
obo:GO_0030133 a rdfs:Class ;
rdfs:label "transport vesicle" ;
rdfs:comment "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." ;
rdfs:subClassOf obo:GO_0031410 .
obo:WBPhenotype_0000563 a rdfs:Class ;
rdfs:label "shrinker" ;
rdfs:comment "The whole body undergoes longitudinal shortening in response to head touch or tail touch (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001701 .
obo:WBPhenotype_0001258 a rdfs:Class ;
rdfs:label "RNAi enhanced" ;
rdfs:comment "Animals show increased susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:CHEBI_15138 a rdfs:Class ;
rdfs:label "sulfide(2-)" ;
rdfs:comment "A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide." ;
rdfs:subClassOf obo:CHEBI_79388 .
obo:GO_0060465 a rdfs:Class ;
rdfs:label "pharynx development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0040026 a rdfs:Class ;
rdfs:label "positive regulation of vulval development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ;
rdfs:subClassOf obo:GO_0040028 , obo:GO_0051094 , obo:GO_0065007 .
obo:WBbt_0005741 a rdfs:Class ;
rdfs:label "tail" ;
rdfs:comment "posterior region, from rectum to the end" ;
rdfs:subClassOf obo:WBbt_0005738 .
obo:CHEBI_18140 a rdfs:Class ;
rdfs:label "hydrogen halide" ;
rdfs:subClassOf obo:CHEBI_33405 .
obo:GO_1904746 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic process involved in development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0051093 , obo:GO_0065007 , obo:GO_1904748 .
obo:WBPhenotype_0000178 a rdfs:Class ;
rdfs:label "cell degeneration" ;
rdfs:comment "Cells are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles." ;
rdfs:subClassOf obo:WBPhenotype_0000533 , obo:WBPhenotype_0000729 .
obo:GO_0031647 a rdfs:Class ;
rdfs:label "regulation of protein stability" ;
rdfs:comment "Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation." ;
rdfs:subClassOf obo:GO_0065008 .
obo:GO_0065004 a rdfs:Class ;
rdfs:label "protein-DNA complex assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex." ;
rdfs:subClassOf obo:GO_0065003 , obo:GO_0071824 .
obo:CHEBI_38867 a rdfs:Class ;
rdfs:label "anaesthetic" ;
rdfs:comment "Substance which produces loss of feeling or sensation." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:WBPhenotype_0000579 a rdfs:Class ;
rdfs:label "organism segment development variant" ;
rdfs:comment "Variations in the progression of the overall structure or appearance of any anterior/posterior section of an animal's anatomy over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000531 .
obo:WBbt_0000100 a rdfs:Class ;
rdfs:label "C. elegans anatomical entity" ;
rdfs:comment "An anatomical entity of the nematode Caenorhabditis elegans." .
obo:GO_0045937 a rdfs:Class ;
rdfs:label "positive regulation of phosphate metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ;
rdfs:subClassOf obo:GO_0010562 , obo:GO_0065007 .
obo:GO_0032543 a rdfs:Class ;
rdfs:label "mitochondrial translation" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code." ;
rdfs:subClassOf obo:GO_0006412 .
obo:GO_0070192 a rdfs:Class ;
rdfs:label "chromosome organization involved in meiotic cell cycle" ;
rdfs:comment "A process of chromosome organization that is involved in a meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0051276 , obo:GO_1903046 .
obo:CHEBI_25710 a rdfs:Class ;
rdfs:label "organophosphorus compound" ;
rdfs:comment "An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters." ;
rdfs:subClassOf obo:CHEBI_26082 , obo:CHEBI_33285 .
obo:WBPhenotype_0001187 a rdfs:Class ;
rdfs:label "division EMS before P2 early emb" ;
rdfs:comment "EMS divides before P2." ;
rdfs:subClassOf obo:WBPhenotype_0001120 .
obo:GO_0032063 a rdfs:Class ;
rdfs:label "negative regulation of translational initiation in response to osmotic stress" ;
rdfs:comment "Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ;
rdfs:subClassOf obo:GO_0032057 , obo:GO_0032061 , obo:GO_0043561 , obo:GO_0065007 .
obo:GO_1990580 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translational termination" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic translational termination." ;
rdfs:subClassOf obo:GO_0006449 , obo:GO_0050789 , obo:GO_2000765 .
obo:WBPhenotype_0000539 a rdfs:Class ;
rdfs:label "dorsal nerve cord development variant" ;
rdfs:comment "Variations in the progression of the anatomical structures that consist of processes of ventral cord motor neurons that send commissures to the dorsal side, as well as processes of certain head and tail neurons, over time from initial formation to mature structure compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000945 .
obo:WBPhenotype_0001441 a rdfs:Class ;
rdfs:label "aqueous positive chemotaxis defective" ;
rdfs:comment "Animals fail to move towards attractive water-soluble chemicals." ;
rdfs:subClassOf obo:WBPhenotype_0000015 , obo:WBPhenotype_0001047 .
obo:CHEBI_16042 a rdfs:Class ;
rdfs:label "halide anion" ;
rdfs:comment "A monoatomic monoanion resulting from the addition of an electron to any halogen atom." ;
rdfs:subClassOf obo:CHEBI_33429 , obo:CHEBI_79389 .
obo:WBPhenotype_0001399 a rdfs:Class ;
rdfs:label "cell membrane morphology variant" ;
rdfs:comment "Any variation in the structure, form or composition of the semipermeable lipid bilayer that creates a boundary between the interior and exterior environment for cells, cellular organelles and tissues, within an organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002089 .
obo:WBPhenotype_0002079 a rdfs:Class ;
rdfs:label "delayed reproductive maturity" ;
rdfs:comment "The animal's ability to reproduce, or start of reproduction occurs later than that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000045 .
obo:WBPhenotype_0002252 a rdfs:Class ;
rdfs:label "increased susceptibility to viral infection" ;
rdfs:comment "Animals are more prone to infection by virus compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001013 .
obo:GO_0034263 a rdfs:Class ;
rdfs:label "positive regulation of autophagy in response to ER overload" ;
rdfs:comment "The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy." ;
rdfs:subClassOf obo:GO_0006983 , obo:GO_0010508 .
obo:WBPhenotype_0000157 a rdfs:Class ;
rdfs:label "posterior body wall contraction defecation cycle variant" ;
rdfs:comment "Animals exhibit variations in the sustained posterior body muscle contractions that precede the remaining contractions of the defecation cycle compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000210 .
obo:WBPhenotype_0002454 a rdfs:Class ;
rdfs:label "enhanced recovery pumping response to light" ;
rdfs:comment "Animals exhibit an enhanced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increases to a greater extent than in controls." ;
rdfs:subClassOf obo:WBPhenotype_0002453 .
obo:WBPhenotype_0002534 a rdfs:Class ;
rdfs:label "antimicrobial gene expression variant"@en ;
rdfs:comment "Animals exhibit variations in the expression of one or more known, endogenous, antimicrobial genes, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:GO_0097194 a rdfs:Class ;
rdfs:label "execution phase of apoptosis" ;
rdfs:comment "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0045905 a rdfs:Class ;
rdfs:label "positive regulation of translational termination" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translational termination." ;
rdfs:subClassOf obo:GO_0006449 , obo:GO_0043243 , obo:GO_0045727 , obo:GO_0065007 .
obo:GO_0048588 a rdfs:Class ;
rdfs:label "developmental cell growth" ;
rdfs:comment "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." ;
rdfs:subClassOf obo:GO_0016049 , obo:GO_0048589 .
obo:GO_0032103 a rdfs:Class ;
rdfs:label "positive regulation of response to external stimulus" ;
rdfs:comment "Any process that activates, maintains or increases the rate of a response to an external stimulus." ;
rdfs:subClassOf obo:GO_0032101 , obo:GO_0048584 , obo:GO_0065007 .
obo:WBPhenotype_0002219 a rdfs:Class ;
rdfs:label "fluoranthene hypersensitive" ;
rdfs:comment "Animals respond to fluoranthene at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001341 a rdfs:Class ;
rdfs:label "egg laying phentolamine resistant" ;
rdfs:comment "Animals are not induced to lay eggs in reponse to exogenous phentolamine. In C. elegans, phentolamine stimulates egg-laying." ;
rdfs:subClassOf obo:WBPhenotype_0001101 , obo:WBPhenotype_0001338 .
obo:WBPhenotype_0000782 a rdfs:Class ;
rdfs:label "body wall muscle thick filament variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of a robust elongated cytoplasmic filament composed principally of myosin protein compared to control animals. In C. elegans, thick filaments also contain paramyosin and twitchin (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001889 .
obo:WBPhenotype_0000208 a rdfs:Class ;
rdfs:label "long defecation cycle" ;
rdfs:comment "The mean time between the onset of the defecation motor program is greater than that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000207 .
obo:WBPhenotype_0002064 a rdfs:Class ;
rdfs:label "maintenance of gene silencing defective" ;
rdfs:comment "Animals express genes that had been targeted for heritable silencing in previous generations." ;
rdfs:subClassOf obo:WBPhenotype_0002063 .
obo:WBPhenotype_0001317 a rdfs:Class ;
rdfs:label "evoked postsynaptic amplitude reduced" ;
rdfs:comment "The amplitudes of synaptic currents that are elicited by firing an action potential in a population of axons are decreased, compared to those observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001316 .
obo:GO_0061919 a rdfs:Class ;
rdfs:label "process utilizing autophagic mechanism" ;
rdfs:comment "A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0001269 a rdfs:Class ;
rdfs:label "pathogen induced cell death variant" ;
rdfs:comment "Animals exhibit variations in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001268 .
obo:GO_0051053 a rdfs:Class ;
rdfs:label "negative regulation of DNA metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." ;
rdfs:subClassOf obo:GO_0010605 , obo:GO_0045934 , obo:GO_0051052 , obo:GO_0065007 .
obo:WBPhenotype_0002073 a rdfs:Class ;
rdfs:label "cation homeostasis variant" ;
rdfs:comment "Animals exhibit variations in the regulation of levels, transport, and metabolism of cations within a cell or between a cell and its external environment, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:CHEBI_33447 a rdfs:Class ;
rdfs:label "phospho sugar" ;
rdfs:comment "Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid." ;
rdfs:subClassOf obo:CHEBI_26816 , obo:CHEBI_63367 .
obo:WBPhenotype_0001050 a rdfs:Class ;
rdfs:label "chemosensation variant" ;
rdfs:comment "Animals exhibit variations in any of a series of events in which an organism receives a sensory chemical stimulus, converts it to a molecular signal, and recognizes and characterizes the signal, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001049 .
obo:GO_0000956 a rdfs:Class ;
rdfs:label "nuclear-transcribed mRNA catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells." ;
rdfs:subClassOf obo:GO_0006402 .
obo:WBPhenotype_0002021 a rdfs:Class ;
rdfs:label "synaptic spike frequency variant" ;
rdfs:comment "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed at the synapse, which are independent of presynaptic inputs." ;
rdfs:subClassOf obo:WBPhenotype_0000584 , obo:WBPhenotype_0002023 .
obo:PATO_0002301 a rdfs:Class ;
rdfs:label "decreased quality" ;
rdfs:comment "A quality that has a value that is decreased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0000001 , obo:PATO_0000069 .
obo:CHEBI_5615 a rdfs:Class ;
rdfs:label "halothane" ;
rdfs:comment "A haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_24469 , obo:CHEBI_36683 , obo:CHEBI_37141 , obo:CHEBI_37143 .
obo:CHEBI_37076 a rdfs:Class ;
rdfs:label "ribonucleoside 5'-triphosphate" ;
rdfs:subClassOf obo:CHEBI_37015 .
obo:GO_0035188 a rdfs:Class ;
rdfs:label "hatching" ;
rdfs:comment "The emergence of an immature organism from a protective structure." ;
rdfs:subClassOf obo:GO_0071684 .
obo:WBPhenotype_0002670 a rdfs:Class ;
rdfs:label "healthspan phenotype"@en ;
rdfs:comment "Animals exhibit variations in healthspan, the period within which animals are or appear to be generally healthy as indicated, for example, by mobility, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000576 .
obo:GO_0099177 a rdfs:Class ;
rdfs:label "regulation of trans-synaptic signaling" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0023051 , obo:GO_0065007 .
obo:GO_1903380 a rdfs:Class ;
rdfs:label "positive regulation of mitotic chromosome condensation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090068 , obo:GO_1903379 , obo:GO_1905821 .
obo:WBPhenotype_0001542 a rdfs:Class ;
rdfs:label "dauer feeding suppressed variant" ;
rdfs:comment "Any variation in the inhibition of feeding which is induced/occurs during the dauer stage compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001001 .
obo:WBPhenotype_0001645 a rdfs:Class ;
rdfs:label "protein degradation variant" ;
rdfs:comment "Variations in the chemical reactions and pathways resulting in the directed breakdown of a protein (via the destruction of its native, active configuration) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001644 .
obo:GO_0051452 a rdfs:Class ;
rdfs:label "intracellular pH reduction" ;
rdfs:comment "Any process that reduces the internal pH of a cell, corresponding to an increase in hydrogen ion concentration." ;
rdfs:subClassOf obo:GO_0051453 .
obo:CHEBI_26188 a rdfs:Class ;
rdfs:label "polyketide" ;
rdfs:comment "Natural and synthetic compounds containing alternating carbonyl and methylene groups ('β-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:WBPhenotype_0000142 a rdfs:Class ;
rdfs:label "cell stress response variant" ;
rdfs:comment "Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:WBPhenotype_0000067 , obo:WBPhenotype_0000585 .
obo:GO_0070129 a rdfs:Class ;
rdfs:label "regulation of mitochondrial translation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0062125 , obo:GO_0065007 .
obo:GO_1905844 a rdfs:Class ;
rdfs:label "negative regulation of cellular response to gamma radiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0065007 , obo:GO_1905843 , obo:GO_2001229 .
obo:GO_0043067 a rdfs:Class ;
rdfs:label "regulation of programmed cell death" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0051726 a rdfs:Class ;
rdfs:label "regulation of cell cycle" ;
rdfs:comment "Any process that modulates the rate or extent of progression through the cell cycle." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0000129 a rdfs:Class ;
rdfs:label "temperature induced dauer formation defective" ;
rdfs:comment "Animals do not enter dauer at a temperature that induces dauer formation in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000013 , obo:WBPhenotype_0000639 .
obo:WBbt_0007030 a rdfs:Class ;
rdfs:label "post-embryonic cell" ;
rdfs:comment "a cell that is born in a worm after hatching." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_0097708 a rdfs:Class ;
rdfs:label "intracellular vesicle" ;
rdfs:comment "Any vesicle that is part of the intracellular region." ;
rdfs:subClassOf obo:GO_0031982 , obo:GO_0043231 .
obo:CHEBI_25697 a rdfs:Class ;
rdfs:label "organic cation" ;
rdfs:comment "Any organic ion with a net positive charge." ;
rdfs:subClassOf obo:CHEBI_25699 , obo:CHEBI_36916 .
obo:WBPhenotype_0002204 a rdfs:Class ;
rdfs:label "procorpus contraction defective" ;
rdfs:comment "Animals exhibit defects in the muscle contractions of the anterior region of corpus, the area responsible for allowing food to enter the corpus." ;
rdfs:subClassOf obo:WBPhenotype_0000327 .
obo:CHEBI_22633 a rdfs:Class ;
rdfs:label "arsenite ion" ;
rdfs:comment "An arsenic oxoanion resulting from the removal of one or more protons from arsenous acid." ;
rdfs:subClassOf obo:CHEBI_24834 , obo:CHEBI_35776 .
obo:WBPhenotype_0002548 a rdfs:Class ;
rdfs:label "kinker from conflicting forward and backward body bend propagation"@en ;
rdfs:comment "Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves." ;
rdfs:subClassOf obo:WBPhenotype_0000002 .
obo:CHEBI_52092 a rdfs:Class ;
rdfs:label "ethoxide" ;
rdfs:comment "An organic anion that is the conjugate base of ethanol." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25696 .
obo:WBPhenotype_0002016 a rdfs:Class ;
rdfs:label "biotin chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to biotin as defined by control animals. In C. elegans, biotin is typically an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001441 .
obo:WBPhenotype_0002320 a rdfs:Class ;
rdfs:label "reversal variant" ;
rdfs:comment "Variations in the behavior by which an organism shifts from forward to backward movements." ;
rdfs:subClassOf obo:WBPhenotype_0001702 .
obo:WBbt_0005737 a rdfs:Class ;
rdfs:label "muscular system" ;
rdfs:comment "the organ system that allows the animal move, includes all muscles." ;
rdfs:subClassOf obo:WBbt_0005746 .
obo:CHEBI_23367 a rdfs:Class ;
rdfs:label "molecular entity" ;
rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ;
rdfs:subClassOf obo:CHEBI_24431 .
obo:CHEBI_142513 a rdfs:Class ;
rdfs:label "oxime anion" ;
rdfs:comment "A organic ion resulting from the deprotonation of the hydroxy group of any oxime." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:CHEBI_61697 a rdfs:Class ;
rdfs:label "fatty acid derivative" ;
rdfs:comment "Any organic molecular entity derived from a fatty acid." ;
rdfs:subClassOf obo:CHEBI_18059 .
obo:WBPhenotype_0000023 a rdfs:Class ;
rdfs:label "serotonin hypersensitive" ;
rdfs:comment "Animals respond to serotonin at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000722 a rdfs:Class ;
rdfs:label "nucleolus variant" ;
rdfs:comment "Animals exhibit variations in the appearance of nucleoli compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001028 .
obo:WBPhenotype_0000001 a rdfs:Class ;
rdfs:label "body posture variant" ;
rdfs:comment "Animals exhibit variations in body posture compared to control animals. For example, in C. elegans characteristic sinusoidal body posture is altered." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:WBbt_0005781 a rdfs:Class ;
rdfs:label "smooth muscle" ;
rdfs:subClassOf obo:WBbt_0005780 , obo:WBbt_0007810 .
obo:GO_0030856 a rdfs:Class ;
rdfs:label "regulation of epithelial cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 , obo:GO_2000026 .
obo:GO_1905213 a rdfs:Class ;
rdfs:label "negative regulation of mitotic chromosome condensation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0065007 , obo:GO_1902340 , obo:GO_1903379 .
obo:WBPhenotype_0002133 a rdfs:Class ;
rdfs:label "ooplasmic streaming slow" ;
rdfs:comment "The bulk flow of cytoplasm in the egg, that facilitates mixing of ooplasm, occurs at a reduced rate compared to that measured for controls." ;
rdfs:subClassOf obo:WBPhenotype_0000360 .
obo:WBPhenotype_0001699 a rdfs:Class ;
rdfs:label "localized movement variant" ;
rdfs:comment "Specific body regions of an animal display variations in movement compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001206 .
obo:CHEBI_73541 a rdfs:Class ;
rdfs:label "organic heterobicyclic ring" ;
rdfs:comment "A bicyclic organic group that contains both carbon and hetero atoms." ;
rdfs:subClassOf obo:CHEBI_52845 .
obo:GO_0044839 a rdfs:Class ;
rdfs:label "cell cycle G2/M phase transition" ;
rdfs:comment "The cell cycle process by which a cell in G2 phase commits to M phase." ;
rdfs:subClassOf obo:GO_0044770 .
obo:CHEBI_35586 a rdfs:Class ;
rdfs:label "1H-purine" ;
rdfs:comment "The 1H-tautomer of purine." ;
rdfs:subClassOf obo:CHEBI_35584 .
obo:GO_0009895 a rdfs:Class ;
rdfs:label "negative regulation of catabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0009894 , obo:GO_0065007 .
obo:WBPhenotype_0002523 a rdfs:Class ;
rdfs:label "slow recovery from starvation-induced L1 arrest"@en ;
rdfs:comment "Animals exhibit a slow recovery from starvation-induced L1 arrest, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002522 .
obo:GO_0032507 a rdfs:Class ;
rdfs:label "maintenance of protein location in cell" ;
rdfs:comment "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0051651 .
obo:WBPhenotype_0002222 a rdfs:Class ;
rdfs:label "uterus vacuole" ;
rdfs:comment "The uterus contains cavities, possibly indicative of inappropriate cell death." ;
rdfs:subClassOf obo:WBPhenotype_0001395 .
obo:CHEBI_33292 a rdfs:Class ;
rdfs:label "fuel" ;
rdfs:comment "An energy-rich substance that can be transformed with release of usable energy." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:WBPhenotype_0000215 a rdfs:Class ;
rdfs:label "no germ line" ;
rdfs:comment "Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline." ;
rdfs:subClassOf obo:WBPhenotype_0000812 , obo:WBPhenotype_0002556 .
obo:WBPhenotype_0001324 a rdfs:Class ;
rdfs:label "cell ionizing radiation response variant" ;
rdfs:comment "Cells exhibit variations in their response to ionizing radiation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000142 , obo:WBPhenotype_0000686 .
obo:GO_0051495 a rdfs:Class ;
rdfs:label "positive regulation of cytoskeleton organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0051493 , obo:GO_0065007 .
obo:CHEBI_22327 a rdfs:Class ;
rdfs:label "aliphatic sulfide" ;
rdfs:subClassOf obo:CHEBI_16385 .
obo:WBPhenotype_0002443 a rdfs:Class ;
rdfs:label "spicule protraction variant" ;
rdfs:comment "Any variation in the specific actions or reactions of the male that are associated with the protraction of the male copulatory spicules compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000279 .
obo:GO_0051098 a rdfs:Class ;
rdfs:label "regulation of binding" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:WBPhenotype_0000423 a rdfs:Class ;
rdfs:label "head muscle contraction variant" ;
rdfs:comment "Any variation in the contractions of the muscles in the most anterior body region of the animal compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000611 .
obo:GO_0030855 a rdfs:Class ;
rdfs:label "epithelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0042023 a rdfs:Class ;
rdfs:label "DNA endoreduplication" ;
rdfs:comment "Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes." ;
rdfs:subClassOf obo:GO_0044786 .
obo:GO_0050890 a rdfs:Class ;
rdfs:label "cognition" ;
rdfs:comment "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." ;
rdfs:subClassOf obo:GO_0050877 .
obo:WBPhenotype_0000745 a rdfs:Class ;
rdfs:label "transposon silencing variant" ;
rdfs:comment "Animals exhibit variations in the activity of endogenous transposons compared to control. In C. elegans transposon activity is often measured by the rate of reversion of mutations induced by transposon insertions." ;
rdfs:subClassOf obo:WBPhenotype_0002063 .
obo:WBbt_0006798 a rdfs:Class ;
rdfs:label "sperm" ;
rdfs:comment "Male haploid germ cell." ;
rdfs:subClassOf obo:WBbt_0006796 .
obo:CL_0000618 a rdfs:Class ;
rdfs:label "sheath cell" ;
rdfs:subClassOf obo:CL_0000075 .
obo:CHEBI_59558 a rdfs:Class ;
rdfs:label "medium-chain fatty acid anion" ;
rdfs:comment "A fatty acid anion resulting from the deprotonation of the carboxylic acid moiety of a medium-chain fatty acid." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:GO_0048260 a rdfs:Class ;
rdfs:label "positive regulation of receptor-mediated endocytosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." ;
rdfs:subClassOf obo:GO_0045807 , obo:GO_0048259 , obo:GO_0065007 .
obo:GO_0050772 a rdfs:Class ;
rdfs:label "positive regulation of axonogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of axonogenesis." ;
rdfs:subClassOf obo:GO_0031346 , obo:GO_0050769 , obo:GO_0050770 , obo:GO_0065007 .
obo:WBPhenotype_0000542 a rdfs:Class ;
rdfs:label "fat" ;
rdfs:comment "Animals exhibit an increased girth compared to a control animal of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0001727 .
obo:WBPhenotype_0002397 a rdfs:Class ;
rdfs:label "tumor prolapse frequency increased" ;
rdfs:comment "Animals with a tumorous germline exhibit an increased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000038 .
obo:CHEBI_16136 a rdfs:Class ;
rdfs:label "hydrogen sulfide" ;
rdfs:comment "A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen." ;
rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_33405 , obo:CHEBI_33535 , obo:CHEBI_37176 .
obo:CHEBI_24828 a rdfs:Class ;
rdfs:label "indoles" ;
rdfs:comment "Any compound containing an indole skeleton." ;
rdfs:subClassOf obo:CHEBI_22728 .
obo:WBPhenotype_0001176 a rdfs:Class ;
rdfs:label "one cell shape defective early emb" ;
rdfs:comment "One-cell embryos have an altered shape." ;
rdfs:subClassOf obo:WBPhenotype_0001135 .
obo:WBbt_0008627 a rdfs:Class ;
rdfs:label "MS lineage cell" ;
rdfs:comment "A cell that is the MS blast cell or is a lineal descendant of MS." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBbt_0008431 a rdfs:Class ;
rdfs:label "mechanosensory neuron" ;
rdfs:comment "neuron that senses and responds to mechanical stimuli, such as touch." ;
rdfs:subClassOf obo:WBbt_0005759 .
obo:GO_0000302 a rdfs:Class ;
rdfs:label "response to reactive oxygen species" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." ;
rdfs:subClassOf obo:GO_0006979 , obo:GO_1901700 .
obo:PATO_0001005 a rdfs:Class ;
rdfs:label "latency" ;
rdfs:comment "A time quality inhering in a bearer by virtue of the time it elapses for the bearer to respond to a stimulus." ;
rdfs:subClassOf obo:PATO_0000502 .
obo:WBPhenotype_0001038 a rdfs:Class ;
rdfs:label "tumorous germline" ;
rdfs:comment "Germ cells do not exit the mitotic cycle, resulting in a expansion of the unspecialized germ cell population compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000823 , obo:WBPhenotype_0002175 .
obo:WBPhenotype_0001384 a rdfs:Class ;
rdfs:label "fertility reduced" ;
rdfs:comment "Animals exhibit a reduction in the production of new individuals that contain some portion of their genetic material inherited from that organism as a result of defective gametes." ;
rdfs:subClassOf obo:WBPhenotype_0000145 .
obo:WBls_0000816 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during adulthood"@en ;
rdfs:comment "A C. elegans life stage that occurs during the adult life stage" ;
rdfs:subClassOf obo:WBls_0000804 .
obo:WBPhenotype_0001810 a rdfs:Class ;
rdfs:label "oocyte septum formation variant" ;
rdfs:comment "Animals exhibit variations in the partitioning of oocytes from each other compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000399 .
obo:CHEBI_231587 a rdfs:Class ;
rdfs:label "cephaeline(2+)" ;
rdfs:subClassOf obo:CHEBI_35274 .
obo:WBPhenotype_0001205 a rdfs:Class ;
rdfs:label "muscimol hypersensitive" ;
rdfs:comment "Animals respond to muscimol at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001918 , obo:WBPhenotype_0002047 .
obo:WBPhenotype_0000717 a rdfs:Class ;
rdfs:label "gene expression variant" ;
rdfs:comment "Variations in the processes that convert a gene's sequence into a mature gene product or products (proteins or RNA), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001696 .
obo:WBPhenotype_0001919 a rdfs:Class ;
rdfs:label "gut granules enlarged" ;
rdfs:comment "Animals exhibit larger inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0002240 .
obo:CHEBI_50925 a rdfs:Class ;
rdfs:label "EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor" ;
rdfs:comment "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine." ;
rdfs:subClassOf obo:CHEBI_76812 .
obo:WBPhenotype_0001661 a rdfs:Class ;
rdfs:label "loss of asymmetry AWC" ;
rdfs:comment "The two morphologically bilaterally symmetric olfactory neurons AWC left (AWCL) and AWC right (AWCR) fail to undergo a left/right asymmetric diversification in cell fate." ;
rdfs:subClassOf obo:WBPhenotype_0001510 , obo:WBPhenotype_0001512 .
obo:WBPhenotype_0000795 a rdfs:Class ;
rdfs:label "body axis behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of one of the longitudinal axes of the extended body of the worm in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000522 .
obo:GO_1990611 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translational initiation in response to stress" ;
rdfs:comment "Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0043558 , obo:GO_0065007 , obo:GO_1904688 , obo:GO_1990497 .
obo:CHEBI_64898 a rdfs:Class ;
rdfs:label "anionic amino-acid residue" ;
rdfs:comment "An amino-acid residue carrying an overall negative charge." ;
rdfs:subClassOf obo:CHEBI_64775 .
obo:WBPhenotype_0001537 a rdfs:Class ;
rdfs:label "mRNA surveillance variant" ;
rdfs:comment "Any variation in the ability of cells to monitor the quality of their mRNAs and degrade any transcripts that are poorly or incompletely translated compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001283 , obo:WBPhenotype_0001826 .
obo:GO_0001940 a rdfs:Class ;
rdfs:label "male pronucleus" ;
rdfs:comment "The pronucleus originating from the spermatozoa that was involved in fertilization." ;
rdfs:subClassOf obo:GO_0045120 .
obo:GO_0051050 a rdfs:Class ;
rdfs:label "positive regulation of transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0051049 , obo:GO_0065007 .
obo:WBPhenotype_0000315 a rdfs:Class ;
rdfs:label "mechanosensation variant" ;
rdfs:comment "Any variation with respect to perception or response to mechanical stimuli compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000525 , obo:WBPhenotype_0000738 .
obo:WBPhenotype_0000596 a rdfs:Class ;
rdfs:label "body behavior variant" ;
rdfs:comment "Activity characteristic of the body is altered compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000580 .
obo:WBPhenotype_0001418 a rdfs:Class ;
rdfs:label "organism hypersensitive desiccation" ;
rdfs:comment "Animals respond to less severe drought-like conditions or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001417 .
obo:GO_1905904 a rdfs:Class ;
rdfs:label "positive regulation of mesoderm formation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mesoderm formation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905902 , obo:GO_2000382 .
obo:CHEBI_33893 a rdfs:Class ;
rdfs:label "reagent" ;
rdfs:comment "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_1904745 a rdfs:Class ;
rdfs:label "Atg1/ULK1 kinase complex assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex." ;
rdfs:subClassOf obo:GO_0065003 .
obo:WBPhenotype_0002316 a rdfs:Class ;
rdfs:label "dwelling variant" ;
rdfs:comment "Animals exhibit variations in the low-speed/high turning movement that restricts them to a confined region compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000641 , obo:WBPhenotype_0000662 .
obo:CL_0000675 a rdfs:Class ;
rdfs:label "female gamete" ;
rdfs:comment "A mature sexual reproductive cell of the female germline." ;
rdfs:subClassOf obo:CL_0000021 , obo:CL_0000300 .
obo:WBPhenotype_0002032 a rdfs:Class ;
rdfs:label "lectin binding variant" ;
rdfs:comment "Animals differ from controls in the range, specificity, or presence of targets for exogenously applied lectins." ;
rdfs:subClassOf obo:WBPhenotype_0002031 .
obo:WBPhenotype_0001049 a rdfs:Class ;
rdfs:label "chemosensory behavior variant" ;
rdfs:comment "Variations in behavior that is dependent upon the sensation of chemicals, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:WBPhenotype_0000276 a rdfs:Class ;
rdfs:label "organism X ray response variant" ;
rdfs:comment "Animals exhibit variations in their response to X-ray radiation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000686 .
obo:GO_0062197 a rdfs:Class ;
rdfs:label "cellular response to chemical stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0033554 , obo:GO_0070887 .
obo:WBPhenotype_0001750 a rdfs:Class ;
rdfs:label "zinc toxicity resistant" ;
rdfs:comment "Animals fail to exhibit toxicity to the concentration of zinc that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to zinc include delayed development or lethality." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001747 .
obo:WBPhenotype_0001486 a rdfs:Class ;
rdfs:label "unfolded protein accumulation" ;
rdfs:comment "Animals accumulate unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria." ;
rdfs:subClassOf obo:WBPhenotype_0000142 , obo:WBPhenotype_0001644 .
obo:CHEBI_33302 a rdfs:Class ;
rdfs:label "pnictogen molecular entity" ;
rdfs:comment "A p-block molecular entity containing any pnictogen." ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:WBPhenotype_0000012 a rdfs:Class ;
rdfs:label "dauer constitutive" ;
rdfs:comment "Formation of dauer larvae under conditions that do not favor dauer formation." ;
rdfs:subClassOf obo:WBPhenotype_0000637 .
obo:UBERON_0002606 a rdfs:Class .
obo:WBPhenotype_0000676 a rdfs:Class ;
rdfs:label "growth rate variant" ;
rdfs:comment "The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000030 .
obo:GO_0051259 a rdfs:Class ;
rdfs:label "protein complex oligomerization" ;
rdfs:comment "The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer." ;
rdfs:subClassOf obo:GO_0065003 .
obo:CHEBI_36830 a rdfs:Class ;
rdfs:label "monoanion" ;
rdfs:subClassOf obo:CHEBI_22563 .
obo:GO_0000910 a rdfs:Class ;
rdfs:label "cytokinesis" ;
rdfs:comment "The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells." ;
rdfs:subClassOf obo:GO_0022402 .
obo:GO_0051149 a rdfs:Class ;
rdfs:label "positive regulation of muscle cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0051147 , obo:GO_0065007 .
obo:WBPhenotype_0000395 a rdfs:Class ;
rdfs:label "no differentiated gametes" ;
rdfs:comment "Animals are agametic (lack mature germ cells)." ;
rdfs:subClassOf obo:WBPhenotype_0000894 .
obo:PATO_0055003 a rdfs:Class ;
rdfs:label "increased rate of occurrence" ;
rdfs:comment "A rate of occurrence that is relatively high." ;
rdfs:subClassOf obo:PATO_0000912 , obo:PATO_0050000 .
obo:CHEBI_25585 a rdfs:Class ;
rdfs:label "nonmetal atom" ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:WBPhenotype_0002117 a rdfs:Class ;
rdfs:label "occurences of decapitation" ;
rdfs:comment "Animals exhibit constrictions in the anterior portion of the head that result in decapitation." ;
rdfs:subClassOf obo:WBPhenotype_0000212 .
obo:WBPhenotype_0002501 a rdfs:Class ;
rdfs:label "ectopic cleavage furrow early emb"@en ;
rdfs:comment "One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells." ;
rdfs:subClassOf obo:WBPhenotype_0001129 .
obo:GO_2000198 a rdfs:Class ;
rdfs:label "negative regulation of ribonucleoprotein complex localization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0065007 , obo:GO_2000197 .
obo:WBPhenotype_0002062 a rdfs:Class ;
rdfs:label "chromosome decondensation failure" ;
rdfs:comment "The process of decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form is abolished." ;
rdfs:subClassOf obo:WBPhenotype_0002061 .
obo:WBPhenotype_0002621 a rdfs:Class ;
rdfs:label "antimicrobial gene expression reduced"@en ;
rdfs:comment "Animals exhibit a decrease in the expression of one or more known, endogenous, antimicrobial genes, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002534 .
obo:WBPhenotype_0002673 a rdfs:Class ;
rdfs:label "nucleolar vacuole phenotype"@en ;
rdfs:comment "Animals exhibit variations in the formation, appearance or functioning of nucleolar vacuoles, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000722 .
obo:GO_0050790 a rdfs:Class ;
rdfs:label "regulation of catalytic activity" ;
rdfs:comment "Any process that modulates the activity of an enzyme." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:GO_0032272 a rdfs:Class ;
rdfs:label "negative regulation of protein polymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." ;
rdfs:subClassOf obo:GO_0031333 , obo:GO_0032271 , obo:GO_0065007 .
obo:WBPhenotype_0001276 a rdfs:Class ;
rdfs:label "ectopic expression transgene" ;
rdfs:comment "Any variation in the cellular expression of a gene product produced by exogenous DNA that has been introduced into the organism such that it now expresses in cells/tissues not seen when compared to the expression of that gene product in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000961 .
obo:GO_0050921 a rdfs:Class ;
rdfs:label "positive regulation of chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ;
rdfs:subClassOf obo:GO_0032103 , obo:GO_0040017 , obo:GO_0050920 , obo:GO_0065007 .
obo:GO_1902845 a rdfs:Class ;
rdfs:label "negative regulation of mitotic spindle elongation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0032888 , obo:GO_0065007 .
obo:WBPhenotype_0001742 a rdfs:Class ;
rdfs:label "lipid synthesis increased" ;
rdfs:comment "The endogenous anabolism of any lipid species has been increased compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000725 , obo:WBPhenotype_0001696 .
obo:GO_0033058 a rdfs:Class ;
rdfs:label "directional locomotion" ;
rdfs:comment "Self-propelled movement of a cell or organism from one location to another along an axis." ;
rdfs:subClassOf obo:GO_0040011 .
obo:GO_0048518 a rdfs:Class ;
rdfs:label "positive regulation of biological process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:CHEBI_59999 a rdfs:Class ;
rdfs:label "chemical substance" ;
rdfs:comment "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." ;
rdfs:subClassOf obo:CHEBI_24431 .
obo:CHEBI_47622 a rdfs:Class ;
rdfs:label "acetate ester" ;
rdfs:comment "Any carboxylic ester where the carboxylic acid component is acetic acid." ;
rdfs:subClassOf obo:CHEBI_33308 .
obo:GO_0019614 a rdfs:Class ;
rdfs:label "catechol-containing compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." ;
rdfs:subClassOf obo:GO_0009712 , obo:GO_0019336 .
obo:WBPhenotype_0000637 a rdfs:Class ;
rdfs:label "dauer formation variant" ;
rdfs:comment "Characteristic entry into the dauer stage is altered compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000308 .
obo:GO_0060561 a rdfs:Class ;
rdfs:label "apoptotic process involved in morphogenesis" ;
rdfs:comment "Any apoptotic process that contributes to the shaping of an anatomical structure." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_1902742 .
obo:WBbt_0008422 a rdfs:Class ;
rdfs:label "sex organ" ;
rdfs:comment "anatomical part of the body which is involved in sexual reproduction and constitutes the reproductive system." ;
rdfs:subClassOf obo:WBbt_0003760 .
obo:GO_0009996 a rdfs:Class ;
rdfs:label "negative regulation of cell fate specification" ;
rdfs:comment "Any process that restricts, stops or prevents a cell from adopting a specific cell fate." ;
rdfs:subClassOf obo:GO_0010454 , obo:GO_0042659 , obo:GO_0065007 .
obo:GO_0002520 a rdfs:Class ;
rdfs:label "immune system development" ;
rdfs:comment "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0048731 .
obo:CHEBI_4046 a rdfs:Class ;
rdfs:label "cyproheptadine" ;
rdfs:comment "The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia." ;
rdfs:subClassOf obo:CHEBI_26151 , obo:CHEBI_32876 .
obo:GO_0043561 a rdfs:Class ;
rdfs:label "regulation of translational initiation in response to osmotic stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ;
rdfs:subClassOf obo:GO_0043557 , obo:GO_0043558 , obo:GO_0065007 .
obo:CHEBI_24839 a rdfs:Class ;
rdfs:label "inorganic salt" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_24866 .
obo:WBPhenotype_0000304 a rdfs:Class ;
rdfs:label "isoamyl alcohol chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to isoamyl alcohol as defined by control animals. In C.elegans isoamyl alcohol is typically attractive." ;
rdfs:subClassOf obo:WBPhenotype_0001438 , obo:WBPhenotype_0001472 .
obo:WBPhenotype_0000040 a rdfs:Class ;
rdfs:label "one cell arrest early emb" ;
rdfs:comment "Embryos fail to divide and arrest as one-cell embryos." ;
rdfs:subClassOf obo:WBPhenotype_0001100 .
obo:WBPhenotype_0001832 a rdfs:Class ;
rdfs:label "nuclear pore variant" ;
rdfs:comment "Any variation that disrupts the assembly, distribution, localization or organization of any of the numerous similar discrete openings in the nuclear envelope, where the inner and outer nuclear membranes are joined." ;
rdfs:subClassOf obo:WBPhenotype_0002037 .
obo:GO_0051248 a rdfs:Class ;
rdfs:label "negative regulation of protein metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." ;
rdfs:subClassOf obo:GO_0010605 , obo:GO_0051246 , obo:GO_0065007 .
obo:GO_1901880 a rdfs:Class ;
rdfs:label "negative regulation of protein depolymerization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." ;
rdfs:subClassOf obo:GO_0043242 , obo:GO_0065007 , obo:GO_1901879 .
obo:CHEBI_19834 a rdfs:Class ;
rdfs:label "3',5'-cyclic purine nucleotide" ;
rdfs:subClassOf obo:CHEBI_18375 , obo:CHEBI_36982 .
obo:WBbt_0005255 a rdfs:Class ;
rdfs:label "buccal cavity" ;
rdfs:comment "cuticle-lined lumenal region surrounded by pharyngeal epithelium, situated at the anterior end of pharynx." ;
rdfs:subClassOf obo:WBbt_0005732 .
obo:CHEBI_35737 a rdfs:Class ;
rdfs:label "monothiocarboxylic acid" ;
rdfs:comment "Compounds in which one oxygen of a carboxy group has been replaced by divalent sulfur; RC(=O)SH or RC(=S)OH." ;
rdfs:subClassOf obo:CHEBI_33307 .
obo:WBPhenotype_0000568 a rdfs:Class ;
rdfs:label "axon ultrastructure variant" ;
rdfs:comment "Animals display variations in the structure or organization of the components of the axon, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000180 .
obo:WBPhenotype_0001791 a rdfs:Class ;
rdfs:label "defecation cycle temperature compensation variant" ;
rdfs:comment "Animals exhibit variations in temperature dependent differences in the length of their defecation cycle. In C. elegans the length of the cycle is the same at different temperatures, showing temperature compensation." ;
rdfs:subClassOf obo:WBPhenotype_0000207 .
obo:WBPhenotype_0000706 a rdfs:Class ;
rdfs:label "gut granule biogenesis reduced" ;
rdfs:comment "Animals lack birefringent containing compartments in embryonic intestinal cells; however, these compartments appear in adult stages." ;
rdfs:subClassOf obo:WBPhenotype_0000103 , obo:WBPhenotype_0001430 .
obo:CHEBI_35274 a rdfs:Class ;
rdfs:label "ammonium ion derivative" ;
rdfs:comment "A derivative of ammonium, NH4+, in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." ;
rdfs:subClassOf obo:CHEBI_33702 , obo:CHEBI_51143 .
obo:GO_0062014 a rdfs:Class ;
rdfs:label "negative regulation of small molecule metabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0062012 , obo:GO_0065007 .
obo:CHEBI_46845 a rdfs:Class ;
rdfs:label "N-alkylpiperazine" ;
rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_50996 .
obo:WBPhenotype_0001667 a rdfs:Class ;
rdfs:label "methyl methanesulfonate hypersensitive" ;
rdfs:comment "Animals respond to the chemical mutagen methyl methanesulfonate (MMS) a methanesulfonate ester and alkylating agent at a lower concentration or a shorter exposure compared to control animals. In C. elegans, increased sensitivity to MMS can be observed as a decrease in egg hatch upon acute exposure or inhibition of growth after chronic exposure compared to control animals given the same treatment." ;
rdfs:subClassOf obo:WBPhenotype_0000498 , obo:WBPhenotype_0001918 .
obo:GO_0010833 a rdfs:Class ;
rdfs:label "telomere maintenance via telomere lengthening" ;
rdfs:comment "Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA." ;
rdfs:subClassOf obo:GO_0000723 .
obo:WBPhenotype_0000027 a rdfs:Class ;
rdfs:label "organism metabolism processing variant" ;
rdfs:comment "Variations in the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:WBPhenotype_0001430 a rdfs:Class ;
rdfs:label "lysosome organization biogenesis variant" ;
rdfs:comment "Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:CHEBI_50857 a rdfs:Class ;
rdfs:label "anti-allergic agent" ;
rdfs:comment "A drug used to treat allergic reactions." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:WBPhenotype_0002075 a rdfs:Class ;
rdfs:label "eggshell formation variant" ;
rdfs:comment "Embryos exhibit variations in the processes that lead to the construction of the eggshell, a protective structure that minimizes water loss whilst allowing gas exchanges essential for embryonic respiration, compared to controls" ;
rdfs:subClassOf obo:WBPhenotype_0000041 , obo:WBPhenotype_0000258 .
obo:PATO_0001752 a rdfs:Class ;
rdfs:label "peramorphic growth" ;
rdfs:comment "A heterochronic growth quality inhering in an organism, structure, or group of organisms by virtue of the bearer's increased growth." ;
rdfs:subClassOf obo:PATO_0001490 .
obo:GO_0019748 a rdfs:Class ;
rdfs:label "secondary metabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0010639 a rdfs:Class ;
rdfs:label "negative regulation of organelle organization" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0051129 , obo:GO_0065007 .
obo:GO_0043525 a rdfs:Class ;
rdfs:label "positive regulation of neuron apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0043523 , obo:GO_0065007 .
obo:GO_0099024 a rdfs:Class ;
rdfs:label "plasma membrane invagination" ;
rdfs:comment "An infolding of the plasma membrane." ;
rdfs:subClassOf obo:GO_0010324 .
obo:CHEBI_59561 a rdfs:Class ;
rdfs:label "diamino acid anion" ;
rdfs:comment "An organic anion that is the conjugate base of diamino acid." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:WBPhenotype_0001198 a rdfs:Class ;
rdfs:label "somatic sheath physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic sheath system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000929 , obo:WBPhenotype_0000990 , obo:WBPhenotype_0001197 .
obo:CHEBI_33598 a rdfs:Class ;
rdfs:label "carbocyclic compound" ;
rdfs:comment "A homocyclic compound in which all of the ring members are carbon atoms." ;
rdfs:subClassOf obo:CHEBI_33597 , obo:CHEBI_33832 .
obo:WBPhenotype_0001139 a rdfs:Class ;
rdfs:label "nuclear envelope assembly variant early emb" ;
rdfs:comment "Nuclear envelope does not reassemble properly." ;
rdfs:subClassOf obo:WBPhenotype_0001138 , obo:WBPhenotype_0002037 .
obo:PATO_0001818 a rdfs:Class ;
rdfs:label "progressive" ;
rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's increasing over time." ;
rdfs:subClassOf obo:PATO_0000057 .
obo:GO_1904351 a rdfs:Class ;
rdfs:label "negative regulation of protein catabolic process in the vacuole" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole." ;
rdfs:subClassOf obo:GO_0042177 , obo:GO_0065007 , obo:GO_1904350 .
obo:CHEBI_62643 a rdfs:Class ;
rdfs:label "anionic phospholipid" ;
rdfs:comment "Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1−), phosphatidate(2−), phosphatidylglycerol(1−)." ;
rdfs:subClassOf obo:CHEBI_58945 .
obo:CHEBI_29101 a rdfs:Class ;
rdfs:label "sodium(1+)" ;
rdfs:comment "A monoatomic monocation obtained from sodium." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25414 , obo:CHEBI_33504 , obo:CHEBI_37246 , obo:CHEBI_60242 .
obo:WBPhenotype_0001683 a rdfs:Class ;
rdfs:label "spermatogenesis defective hermaphrodite" ;
rdfs:comment "Variations that specifically disrupt sperm production in XX hermaphrodites. By contrast, spermatogenesis in XO males remains unaffected." ;
rdfs:subClassOf obo:WBPhenotype_0000670 .
obo:CHEBI_50299 a rdfs:Class ;
rdfs:label "canonical ribonucleotide residue" ;
rdfs:subClassOf obo:CHEBI_50297 .
obo:WBPhenotype_0001351 a rdfs:Class ;
rdfs:label "protein phosphorylation reduced" ;
rdfs:comment "Animals exhibit decreased levels of protein phosphorylation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001349 .
obo:WBPhenotype_0001702 a rdfs:Class ;
rdfs:label "directionality variant" ;
rdfs:comment "Animals exhibit variations in the directional changes that separate consecutive runs, from that observed for control animals. In C. elegans, these aberrations include variations in the form or extent of omega turns or reversals (shifts from forward to backward movements)." ;
rdfs:subClassOf obo:WBPhenotype_0004017 .
obo:CHEBI_35195 a rdfs:Class ;
rdfs:label "surfactant" ;
rdfs:comment "A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces." ;
rdfs:subClassOf obo:CHEBI_63046 .
obo:GO_0090317 a rdfs:Class ;
rdfs:label "negative regulation of intracellular protein transport" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0033157 , obo:GO_0051224 , obo:GO_0065007 .
obo:CHEBI_37956 a rdfs:Class ;
rdfs:label "histamine antagonist" ;
rdfs:comment "Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists." ;
rdfs:subClassOf obo:CHEBI_37957 , obo:CHEBI_48706 .
obo:WBPhenotype_0004016 a rdfs:Class ;
rdfs:label "dauer nictation behavior variant" ;
rdfs:comment "Any variation in the behavior exhibited by dauer larva in which they crawl up upon the substrate and wave back and forth while standing on their tail compared to control. Nictation is often associated with the search for a new host." ;
rdfs:subClassOf obo:WBPhenotype_0001001 .
obo:WBPhenotype_0002490 a rdfs:Class ;
rdfs:label "ectopic axon outgrowth"@en ;
rdfs:comment "Neurons exhibit axon outgrowth in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0001224 , obo:WBPhenotype_0002491 .
obo:WBPhenotype_0000167 a rdfs:Class ;
rdfs:label "precocious seam cell fusion" ;
rdfs:comment "Seam cells fuse to form a continuous syncytium along the body wall at an earlier stage of development compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000166 , obo:WBPhenotype_0001433 .
obo:WBPhenotype_0002267 a rdfs:Class ;
rdfs:label "mitochondrial content increased" ;
rdfs:comment "Animals exhibit increases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining." ;
rdfs:subClassOf obo:WBPhenotype_0002266 .
obo:CHEBI_16865 a rdfs:Class ;
rdfs:label "gamma-aminobutyric acid" ;
rdfs:comment "A γ-amino acid that is butanoic acid with the amino substituent located at C-4." ;
rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_33707 .
obo:WBbt_0005748 a rdfs:Class ;
rdfs:label "alimentary system" ;
rdfs:subClassOf obo:WBbt_0005746 .
obo:WBPhenotype_0002559 a rdfs:Class ;
rdfs:label "burrowing abnormal"@en ;
rdfs:comment "Animals exhibit abnormalities in their burrowing behavior, in which animals burrow into a solid medium, such as agar, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000643 .
obo:GO_0017148 a rdfs:Class ;
rdfs:label "negative regulation of translation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0010629 , obo:GO_0051248 , obo:GO_0065007 .
obo:GO_1905832 a rdfs:Class ;
rdfs:label "positive regulation of spindle assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of spindle assembly." ;
rdfs:subClassOf obo:GO_0051495 , obo:GO_0065007 , obo:GO_0090068 , obo:GO_0090169 , obo:GO_1902117 .
obo:WBPhenotype_0000088 a rdfs:Class ;
rdfs:label "body muscle displaced" ;
rdfs:comment "The arrangement of the principal muscle cell type whose contractile activity generates body motion in the nematode differs from that observed in control animals. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000861 .
obo:WBbt_0005830 a rdfs:Class ;
rdfs:label "lumbar ganglion" ;
rdfs:comment "The left and right lumbar ganglia lie behind the pre-anal ganglion in the tail, in lateral positions. Each contains 12 neuron cell bodies that send most of their neuronal processes into the ventral nerve cord via lumbar commissures and the pre-anal ganglion. There is no local neuropil in these ganglia in the hermaphrodite, instead they form most synapses in the pre-anal ganglion. Most lumbar neurons have sensory functions. In the adult male tail, these two ganglia gain many additional neurons and have some local neuropil. The lumbar neurons lie in close association with the lateral hypodermis, and most are posterior to the anus." ;
rdfs:subClassOf obo:WBbt_0006977 .
obo:GO_0032297 a rdfs:Class ;
rdfs:label "negative regulation of DNA-templated DNA replication initiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication." ;
rdfs:subClassOf obo:GO_0030174 , obo:GO_0065007 , obo:GO_2000104 .
obo:CHEBI_23014 a rdfs:Class ;
rdfs:label "carbon oxide" ;
rdfs:subClassOf obo:CHEBI_25701 , obo:CHEBI_36963 .
obo:WBPhenotype_0000402 a rdfs:Class ;
rdfs:label "avoids bacterial lawn" ;
rdfs:comment "Lawn avoidance refers to behavior in which animals initially enter the bacterial lawn but later exit and remain near the edge of the bacteria. Lawn avoidance is often a response to bacterial food, that is pathogenic or low quality to the animal." ;
rdfs:subClassOf obo:WBPhenotype_0000659 , obo:WBPhenotype_0002545 .
obo:GO_0090267 a rdfs:Class ;
rdfs:label "positive regulation of mitotic cell cycle spindle assembly checkpoint" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090068 , obo:GO_0090232 , obo:GO_0090266 .
obo:WBPhenotype_0002128 a rdfs:Class ;
rdfs:label "leaving assay defective" ;
rdfs:comment "Males remain on food in the absence of mates, a defect in male mate-searching behavior observed in control males." ;
rdfs:subClassOf obo:WBPhenotype_0001983 , obo:WBPhenotype_0004031 .
obo:CHEBI_24431 a rdfs:Class ;
rdfs:label "chemical entity" ;
rdfs:comment "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." .
obo:WBPhenotype_0004009 a rdfs:Class ;
rdfs:label "approximate vulval location variant" ;
rdfs:comment "Any variation in the mating process that includes the male stopping at the vulva (usually after backing) compared to control. In C. elegans general vulva location (stopping) requires the hook sensillum." ;
rdfs:subClassOf obo:WBPhenotype_0000649 .
obo:CL_0002321 a rdfs:Class ;
rdfs:label "embryonic cell (metazoa)" ;
rdfs:comment "A cell of the embryo." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_1903742 a rdfs:Class ;
rdfs:label "regulation of anterograde synaptic vesicle transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901608 , obo:GO_1902803 .
obo:WBPhenotype_0000773 a rdfs:Class ;
rdfs:label "chromosome segregation variant" ;
rdfs:comment "Any variation in the processes that regulate the apportionment of chromosomes to each of two daughter cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000585 .
obo:GO_1905082 a rdfs:Class ;
rdfs:label "regulation of mitochondrial translational elongation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitochondrial translational elongation." ;
rdfs:subClassOf obo:GO_0006448 , obo:GO_0065007 .
obo:WBPhenotype_0000990 a rdfs:Class ;
rdfs:label "muscle cell physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the muscle cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000611 .
obo:WBPhenotype_0000574 a rdfs:Class ;
rdfs:label "excretory canal short" ;
rdfs:comment "The structure made by the processes of the excretory canal cell is reduced in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000704 .
obo:CHEBI_39141 a rdfs:Class ;
rdfs:label "Bronsted acid" ;
rdfs:comment "A molecular entity capable of donating a hydron to an acceptor (Brønsted base)." ;
rdfs:subClassOf obo:CHEBI_17891 , obo:CHEBI_37527 .
obo:WBPhenotype_0000733 a rdfs:Class ;
rdfs:label "catalysis variant" ;
rdfs:comment "Any variation in the catalysis of a biochemical reaction compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ;
rdfs:subClassOf obo:WBPhenotype_0000727 .
obo:WBPhenotype_0002338 a rdfs:Class ;
rdfs:label "body proportion variant" ;
rdfs:comment "Animals exhibit variations in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000231 .
obo:GO_0016459 a rdfs:Class ;
rdfs:label "myosin complex" ;
rdfs:comment "A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes." ;
rdfs:subClassOf obo:GO_0032991 .
obo:GO_1904092 a rdfs:Class ;
rdfs:label "regulation of autophagic cell death" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of autophagic cell death." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0065007 .
obo:CHEBI_50218 a rdfs:Class ;
rdfs:label "EC 3.1.4.* (phosphoric diester hydrolase) inhibitor" ;
rdfs:comment "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*)." ;
rdfs:subClassOf obo:CHEBI_76760 .
obo:CHEBI_26921 a rdfs:Class ;
rdfs:label "tetrahydropyridine" ;
rdfs:subClassOf obo:CHEBI_26421 .
obo:CHEBI_79387 a rdfs:Class ;
rdfs:label "trivalent inorganic anion" ;
rdfs:comment "Any inorganic anion with a valency of three." ;
rdfs:subClassOf obo:CHEBI_24834 .
obo:GO_0048599 a rdfs:Class ;
rdfs:label "oocyte development" ;
rdfs:comment "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0007281 .
obo:WBPhenotype_0002406 a rdfs:Class ;
rdfs:label "aberrant posteriorly-directed neurite" ;
rdfs:comment "Any neurite that is extended towards the posterior of the animal from neurons that in wild-type animals make only anterior projections (e.g. D-type neurons in C. elegans)." ;
rdfs:subClassOf obo:WBPhenotype_0002393 .
obo:WBPhenotype_0000893 a rdfs:Class ;
rdfs:label "male germline proliferation variant" ;
rdfs:comment "Nuclear divisions in the germ line of male animals are either expanded are reduced compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000823 .
obo:WBPhenotype_0000265 a rdfs:Class ;
rdfs:label "odorant positive chemotaxis variant" ;
rdfs:comment "Movement towards typically attractive volatile organic chemicals is altered as defined by control animals. In C. elegans, these odorants are typically sensed by the AWA and AWC neurons." ;
rdfs:subClassOf obo:WBPhenotype_0000635 , obo:WBPhenotype_0001048 .
obo:CHEBI_38869 a rdfs:Class ;
rdfs:label "general anaesthetic" ;
rdfs:comment "Substance that produces loss of consciousness." ;
rdfs:subClassOf obo:CHEBI_38867 .
obo:GO_1905559 a rdfs:Class ;
rdfs:label "positive regulation of mitotic nuclear envelope disassembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_0090068 , obo:GO_1905557 .
obo:WBPhenotype_0001340 a rdfs:Class ;
rdfs:label "egg laying imipramine resistant" ;
rdfs:comment "Animals are not induced to lay eggs in reponse to exogenous imipramine. In C. elegans, imipramine stimulates egg-laying." ;
rdfs:subClassOf obo:WBPhenotype_0000340 , obo:WBPhenotype_0001101 .
obo:CHEBI_10545 a rdfs:Class ;
rdfs:label "electron" ;
rdfs:comment "Elementary particle not affected by the strong force having a spin ½, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." ;
rdfs:subClassOf obo:CHEBI_36338 .
obo:WBPhenotype_0001555 a rdfs:Class ;
rdfs:label "dauer sensory system morphology variant" ;
rdfs:comment "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the dauer sensory system, compared to control. The dauer sensory system is used to perceive the physical and chemical environment during the dauer larval stage." ;
rdfs:subClassOf obo:WBPhenotype_0001545 .
obo:WBPhenotype_0002352 a rdfs:Class ;
rdfs:label "tRNA expression increased" ;
rdfs:comment "Animals exhibit elevated levels of transfer RNA compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000135 .
obo:CHEBI_83821 a rdfs:Class ;
rdfs:label "amino-acid derivative" ;
rdfs:comment "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:WBPhenotype_0001244 a rdfs:Class ;
rdfs:label "intraflagellar transport absent" ;
rdfs:comment "Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is completely abolished." ;
rdfs:subClassOf obo:WBPhenotype_0000854 .
obo:WBPhenotype_0000384 a rdfs:Class ;
rdfs:label "axon guidance variant" ;
rdfs:comment "Variations in the cue-directed extension of an axon towards a specific target site compared to control. (Axon guidance often depends on a combination of attractive and repulsive cues)." ;
rdfs:subClassOf obo:WBPhenotype_0000944 , obo:WBPhenotype_0001224 .
obo:CHEBI_76661 a rdfs:Class ;
rdfs:label "EC 2.3.* (acyltransferase) inhibitor" ;
rdfs:comment "A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*)." ;
rdfs:subClassOf obo:CHEBI_71300 .
obo:GO_2001224 a rdfs:Class ;
rdfs:label "positive regulation of neuron migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuron migration." ;
rdfs:subClassOf obo:GO_0030335 , obo:GO_0065007 , obo:GO_2001222 .
obo:WBPhenotype_0000843 a rdfs:Class ;
rdfs:label "male mating efficiency reduced" ;
rdfs:comment "The number of cross progeny sired by males is reduced compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000648 .
obo:CHEBI_36093 a rdfs:Class ;
rdfs:label "inorganic chloride" ;
rdfs:subClassOf obo:CHEBI_23114 , obo:CHEBI_24839 .
obo:WBPhenotype_0002180 a rdfs:Class ;
rdfs:label "apoptotic cell shedding variant" ;
rdfs:comment "Animals exhibit variations in the process by which cells having undergone programmed cell death are shed or extruded into the extracellular environment." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:GO_0071025 a rdfs:Class ;
rdfs:label "RNA surveillance" ;
rdfs:comment "A process that identifies and degrades defective or aberrant RNAs." ;
rdfs:subClassOf obo:GO_0006401 .
obo:WBbt_0008589 a rdfs:Class ;
rdfs:label "D lineage cell" ;
rdfs:comment "A cell that is the D blast cell or is a lineal descendant of D." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBPhenotype_0000413 a rdfs:Class ;
rdfs:label "pharyngeal muscle paralyzed" ;
rdfs:comment "Pharyngeal muscle is immobilized resulting in lack of pumping or lack of response to external stimulation." ;
rdfs:subClassOf obo:WBPhenotype_0000980 .
obo:WBPhenotype_0001373 a rdfs:Class ;
rdfs:label "protein RNA interaction abolished" ;
rdfs:comment "Animals lack a specific protein-RNA interaction observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001371 .
obo:GO_1904289 a rdfs:Class ;
rdfs:label "regulation of mitotic DNA damage checkpoint" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0065007 , obo:GO_2000001 .
obo:CHEBI_47882 a rdfs:Class ;
rdfs:label "cyclic polypyrrole" ;
rdfs:subClassOf obo:CHEBI_38077 .
obo:CHEBI_48705 a rdfs:Class ;
rdfs:label "agonist" ;
rdfs:comment "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:GO_0050850 a rdfs:Class ;
rdfs:label "positive regulation of calcium-mediated signaling" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling." ;
rdfs:subClassOf obo:GO_0050848 , obo:GO_0065007 , obo:GO_1902533 .
obo:WBPhenotype_0001887 a rdfs:Class ;
rdfs:label "excess seam cells" ;
rdfs:comment "Animals execute supernumerary cell divisions during the development of the lateral, alae-producing epithelial cells, resulting in a larger number of these cells than control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002175 , obo:WBPhenotype_0002569 .
obo:WBPhenotype_0000778 a rdfs:Class ;
rdfs:label "feeding inefficient" ;
rdfs:comment "Animals are unable to ingest nutrients at a rate similar to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000659 .
obo:GO_0046823 a rdfs:Class ;
rdfs:label "negative regulation of nucleocytoplasmic transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0046822 , obo:GO_0065007 .
obo:CHEBI_3533 a rdfs:Class ;
rdfs:label "cephaeline" ;
rdfs:comment "A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions." ;
rdfs:subClassOf obo:CHEBI_61692 .
obo:WBPhenotype_0001492 a rdfs:Class ;
rdfs:label "no back end" ;
rdfs:comment "Animals lack a properly developed posterior region compared to control. In C. elegans, mutants exhibit a severely deformed posterior region with a variable knob-like shape; accompanied by arrest at about the time of hatching with fairly normal pharyngeal and anterior development. Most mutants arrest as L1 larvae, and 5% do not hatch." ;
rdfs:subClassOf obo:WBPhenotype_0000081 , obo:WBPhenotype_0000793 , obo:WBPhenotype_0000800 , obo:WBPhenotype_0000867 .
obo:WBPhenotype_0000784 a rdfs:Class ;
rdfs:label "male fertility variant" ;
rdfs:comment "Males exhibit variations in the time of onset or duration of the fertile period owing to differences in sperm competence and/or function compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000145 .
obo:GO_0050821 a rdfs:Class ;
rdfs:label "protein stabilization" ;
rdfs:comment "Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation." ;
rdfs:subClassOf obo:GO_0031647 .
obo:CHEBI_76946 a rdfs:Class ;
rdfs:label "fungal metabolite" ;
rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." ;
rdfs:subClassOf obo:CHEBI_75763 .
obo:GO_0055082 a rdfs:Class ;
rdfs:label "intracellular chemical homeostasis" ;
rdfs:comment "A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell." ;
rdfs:subClassOf obo:GO_0019725 , obo:GO_0048878 .
obo:GO_0032875 a rdfs:Class ;
rdfs:label "regulation of DNA endoreduplication" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of DNA endoreduplication." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0065007 , obo:GO_0090329 .
obo:CHEBI_138103 a rdfs:Class ;
rdfs:label "inorganic acid" ;
rdfs:comment "A Brønsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." ;
rdfs:subClassOf obo:CHEBI_39141 .
obo:GO_0030308 a rdfs:Class ;
rdfs:label "negative regulation of cell growth" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." ;
rdfs:subClassOf obo:GO_0001558 , obo:GO_0045926 , obo:GO_0048523 , obo:GO_0065007 .
obo:GO_1902120 a rdfs:Class ;
rdfs:label "negative regulation of meiotic spindle elongation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation." ;
rdfs:subClassOf obo:GO_0045835 , obo:GO_0065007 , obo:GO_1902119 .
obo:GO_0002064 a rdfs:Class ;
rdfs:label "epithelial cell development" ;
rdfs:comment "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." ;
rdfs:subClassOf obo:GO_0048468 .
obo:WBPhenotype_0000503 a rdfs:Class ;
rdfs:label "endoreduplication variant" ;
rdfs:comment "Any variation in the multiple rounds of DNA replication that take place without chromosome condensation, segregation or cytokinesis compared to control. In C. elegans this process is normally seen in intestinal nuclei during each larval lethargus which results in adult intestinal nuclei with 32 copies (32C) of each chromosome(Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000433 .
obo:WBbt_0005730 a rdfs:Class ;
rdfs:label "epithelial system" ;
rdfs:comment "lies within the body wall, in close relation to nervous system and excretory system." ;
rdfs:subClassOf obo:WBbt_0005746 .
obo:GO_0019538 a rdfs:Class ;
rdfs:label "protein metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a protein. Includes protein modification." ;
rdfs:subClassOf obo:GO_0043170 , obo:GO_0044238 .
obo:GO_0044774 a rdfs:Class ;
rdfs:label "mitotic DNA integrity checkpoint signaling" ;
rdfs:comment "A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction." ;
rdfs:subClassOf obo:GO_0007093 , obo:GO_0031570 .
obo:WBPhenotype_0001531 a rdfs:Class ;
rdfs:label "labial sensillum morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth." ;
rdfs:subClassOf obo:WBPhenotype_0000299 .
obo:PATO_0000040 a rdfs:Class ;
rdfs:label "distance" ;
rdfs:comment "A quality that is the extent of space between two entities." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:GO_0005929 a rdfs:Class ;
rdfs:label "cilium" ;
rdfs:comment "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." ;
rdfs:subClassOf obo:GO_0043227 , obo:GO_0120025 .
obo:GO_0005712 a rdfs:Class ;
rdfs:label "chiasma" ;
rdfs:comment "A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0055001 a rdfs:Class ;
rdfs:label "muscle cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." ;
rdfs:subClassOf obo:GO_0048468 .
obo:WBPhenotype_0000528 a rdfs:Class ;
rdfs:label "body region development variant" ;
rdfs:comment "Variations in the progression of the overall structure or appearance of a discrete region of an animal's anatomy over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000531 .
obo:WBPhenotype_0001650 a rdfs:Class ;
rdfs:label "germ cell death response to 5 FU resistant" ;
rdfs:comment "Germ cell death fails in response to the concentration of 5-FU that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, in addition to cell death, 5-FU exposed animals exhibit condensed germ cell nuclei or unhealthy nuclei." ;
rdfs:subClassOf obo:WBPhenotype_0001649 .
obo:WBPhenotype_0002140 a rdfs:Class ;
rdfs:label "male attraction response variant" ;
rdfs:comment "Males do not respond to small molecules or compounds that have been shown to attract control males. This phenotype is often measured by an increase in reversal frequency or time spent in a specified scoring region" ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:WBPhenotype_0000665 a rdfs:Class ;
rdfs:label "connection of gonad variant" ;
rdfs:comment "Any variation that disrupts the connectivity between the somatic gonad and the adjoining tissues compared to control. In C. elegans this connnection is between the somatic gonad and the vulva in hermaphrodites and between the somatic gonad and proctodeum in males." ;
rdfs:subClassOf obo:WBPhenotype_0000605 .
obo:WBPhenotype_0002345 a rdfs:Class ;
rdfs:label "forward locomotion variant" ;
rdfs:comment "Variations in the spontaneous or induced forward crawling locomotion of an animal compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000643 .
obo:GO_0051301 a rdfs:Class ;
rdfs:label "cell division" ;
rdfs:comment "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." ;
rdfs:subClassOf obo:GO_0009987 .
obo:CHEBI_5924 a rdfs:Class ;
rdfs:label "EC 3.4.21.* (serine endopeptidase) inhibitor" ;
rdfs:comment "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*)." ;
rdfs:subClassOf obo:CHEBI_60258 .
obo:WBPhenotype_0002464 a rdfs:Class ;
rdfs:label "multiple hooks" ;
rdfs:comment "Male animals exhibit multiple copulatory hooks. In wild type C. elegans males, a single hook is normally present." ;
rdfs:subClassOf obo:WBPhenotype_0002209 .
obo:CHEBI_33083 a rdfs:Class ;
rdfs:label "fluoranthene" ;
rdfs:comment "An ortho- and peri-fused polycyclic arene consisting of a naphthalene and benzene unit connected by a five-membered ring." ;
rdfs:subClassOf obo:CHEBI_35300 .
obo:WBPhenotype_0000350 a rdfs:Class ;
rdfs:label "hermaphrodite tail spike variant" ;
rdfs:comment "Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the hermaphrodite tail compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000968 .
obo:GO_0048812 a rdfs:Class ;
rdfs:label "neuron projection morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." ;
rdfs:subClassOf obo:GO_0120039 .
obo:CHEBI_62031 a rdfs:Class ;
rdfs:label "polar amino acid zwitterion" ;
rdfs:comment "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:WBPhenotype_0001072 a rdfs:Class ;
rdfs:label "response to food variant" ;
rdfs:comment "Any variation in the state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to a food stimulus, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:WBPhenotype_0001233 a rdfs:Class ;
rdfs:label "DAPI staining variant" ;
rdfs:comment "Animals exhibit variations in the pattern of a chemical nuclear stain which is commonly used in fixed specimens and produces a bright blue label, compared to control. DAPI (4'-6-Diamidino-2-phenylindole) forms fluorescent complexes with natural double-stranded DNA (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0010002 .
obo:GO_0016203 a rdfs:Class ;
rdfs:label "muscle attachment" ;
rdfs:comment "The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall)." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_1900064 a rdfs:Class ;
rdfs:label "positive regulation of peroxisome organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of peroxisome organization." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0065007 , obo:GO_1900063 .
obo:WBPhenotype_0002191 a rdfs:Class ;
rdfs:label "fewer sex myoblasts" ;
rdfs:comment "Animals produce a reduced number of sex myoblasts compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002174 .
obo:CHEBI_76773 a rdfs:Class ;
rdfs:label "EC 3.1.1.* (carboxylic ester hydrolase) inhibitor" ;
rdfs:comment "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*)." ;
rdfs:subClassOf obo:CHEBI_76760 .
obo:CHEBI_50826 a rdfs:Class ;
rdfs:label "silver nanoparticle" ;
rdfs:comment "A nanoparticle consisting of silver atoms." ;
rdfs:subClassOf obo:CHEBI_33966 , obo:CHEBI_52855 .
obo:GO_0040001 a rdfs:Class ;
rdfs:label "establishment of mitotic spindle localization" ;
rdfs:comment "The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs." ;
rdfs:subClassOf obo:GO_0051293 , obo:GO_1902850 .
obo:WBPhenotype_0001847 a rdfs:Class ;
rdfs:label "sterol induced dauer formation variant" ;
rdfs:comment "Variations in the processes that facilitate/permit dauer entry when exposed to specific sterol molecules, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001539 .
obo:CHEBI_35235 a rdfs:Class ;
rdfs:label "L-cysteine zwitterion" ;
rdfs:subClassOf obo:CHEBI_35237 .
obo:WBPhenotype_0000585 a rdfs:Class ;
rdfs:label "cell homeostasis metabolism variant" ;
rdfs:comment "Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0000626 a rdfs:Class ;
rdfs:label "habituation variant" ;
rdfs:comment "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 , obo:WBPhenotype_0000738 .
obo:WBbt_0005460 a rdfs:Class ;
rdfs:label "pharyngeal cell" ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_0042659 a rdfs:Class ;
rdfs:label "regulation of cell fate specification" ;
rdfs:comment "Any process that mediates the adoption of a specific fate by a cell." ;
rdfs:subClassOf obo:GO_0010453 , obo:GO_0065007 .
obo:WBPhenotype_0000882 a rdfs:Class ;
rdfs:label "dendrite development variant" ;
rdfs:comment "Any variation in the processes that influence the generation of neuronal extensions, that carry afferent (incoming) action potentials towards the cell body compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000944 .
obo:GO_0051254 a rdfs:Class ;
rdfs:label "positive regulation of RNA metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." ;
rdfs:subClassOf obo:GO_0010604 , obo:GO_0051252 , obo:GO_0065007 .
obo:GO_0051457 a rdfs:Class ;
rdfs:label "maintenance of protein location in nucleus" ;
rdfs:comment "Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0072595 .
obo:WBPhenotype_0000953 a rdfs:Class ;
rdfs:label "dorsal ganglion development variant" ;
rdfs:comment "Any variation in the progression of the ganglion that lies dorsally beside the nerve ring in the head over time from its initial formation to its mature form compared to control. In C. elegans, It contains neuron cell bodies that send their neuronal processes into the ring and longitudinal nerves, but form no local neuropil separate from the nerve ring. The dorsal ganglion is in close contact with the dorsal hypodermal cord (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000943 .
obo:CHEBI_35267 a rdfs:Class ;
rdfs:label "quaternary ammonium ion" ;
rdfs:comment "A derivative of ammonium, NH4+, in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:WBPhenotype_0002521 a rdfs:Class ;
rdfs:label "gap junction plaque number increased"@en ;
rdfs:comment "One or more cells exhibit an increase in number of gap junction plaques, sets of associated gap junctions, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002520 .
obo:WBPhenotype_0000081 a rdfs:Class ;
rdfs:label "L1 arrest" ;
rdfs:comment "The developmental program of the animals does not continue past the first larval stage (L1)." ;
rdfs:subClassOf obo:WBPhenotype_0000055 , obo:WBPhenotype_0000751 .
obo:CHEBI_25806 a rdfs:Class ;
rdfs:label "oxygen molecular entity" ;
rdfs:subClassOf obo:CHEBI_33304 .
obo:GO_1901562 a rdfs:Class ;
rdfs:label "response to paraquat" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus." ;
rdfs:subClassOf obo:GO_0042221 .
obo:WBPhenotype_0000034 a rdfs:Class ;
rdfs:label "embryonic polarity variant" ;
rdfs:comment "Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:GO_0030016 a rdfs:Class ;
rdfs:label "myofibril" ;
rdfs:comment "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." ;
rdfs:subClassOf obo:GO_0043292 .
obo:WBPhenotype_0001992 a rdfs:Class ;
rdfs:label "extra gonadal sheath cells" ;
rdfs:comment "Animals exhibit an increase in the number of somatic sheath cells surrounding each gonad arm compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000399 , obo:WBPhenotype_0002175 .
obo:WBPhenotype_0002151 a rdfs:Class ;
rdfs:label "mRNA deadenylation variant" ;
rdfs:comment "Animals exhibit variations in the extent to which polyadenylated mRNA transcripts become deadenylated" ;
rdfs:subClassOf obo:WBPhenotype_0001827 .
obo:CHEBI_27136 a rdfs:Class ;
rdfs:label "triol" ;
rdfs:comment "A chemical compound containing three hydroxy groups." ;
rdfs:subClassOf obo:CHEBI_26191 .
obo:GO_0007154 a rdfs:Class ;
rdfs:label "cell communication" ;
rdfs:comment "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0002556 a rdfs:Class ;
rdfs:label "tissue phenotype"@en ;
rdfs:comment "A phenotype affecting a particular tissue." ;
rdfs:subClassOf obo:WBPhenotype_0002551 .
obo:WBPhenotype_0000153 a rdfs:Class ;
rdfs:label "body wall muscle contraction abnormal" ;
rdfs:comment "Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000596 , obo:WBPhenotype_0000611 .
obo:GO_0090266 a rdfs:Class ;
rdfs:label "regulation of mitotic cell cycle spindle assembly checkpoint" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." ;
rdfs:subClassOf obo:GO_0007088 , obo:GO_0010965 , obo:GO_0030071 , obo:GO_0033047 , obo:GO_0065007 , obo:GO_1903504 .
obo:GO_1905865 a rdfs:Class ;
rdfs:label "negative regulation of Atg1/ULK1 kinase complex assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly." ;
rdfs:subClassOf obo:GO_0031333 , obo:GO_0065007 , obo:GO_1905864 .
obo:GO_0032204 a rdfs:Class ;
rdfs:label "regulation of telomere maintenance" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." ;
rdfs:subClassOf obo:GO_0033044 , obo:GO_0051052 , obo:GO_0065007 .
obo:WBPhenotype_0001731 a rdfs:Class ;
rdfs:label "thermal bias in tracking variant" ;
rdfs:comment "Animals exhibit variations in the duration of the trajectory of the forward track in a thermal gradient compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000478 .
obo:GO_2000786 a rdfs:Class ;
rdfs:label "positive regulation of autophagosome assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly." ;
rdfs:subClassOf obo:GO_0016239 , obo:GO_0044090 , obo:GO_0065007 , obo:GO_1902117 , obo:GO_2000785 .
obo:CHEBI_37532 a rdfs:Class ;
rdfs:label "phorbol ester" ;
rdfs:comment "Esters of phorbol, originally found in croton oil (from Croton tiglium, of the family Euphorbiaceae). A number of phorbol esters possess activity as tumour promoters and activate the mechanisms associated with cell growth. Some of these are used in experiments as activators of protein kinase C." ;
rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_52557 .
obo:GO_2000002 a rdfs:Class ;
rdfs:label "negative regulation of DNA damage checkpoint" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901977 , obo:GO_2000001 .
obo:WBPhenotype_0000434 a rdfs:Class ;
rdfs:label "sexual maturation defective" ;
rdfs:comment "The developmental process by which a progressive change in the state of some part of an organism specifically contributing to its ability to form offspring is impaired." ;
rdfs:subClassOf obo:WBPhenotype_0000624 .
obo:CHEBI_36344 a rdfs:Class ;
rdfs:label "hadron" ;
rdfs:comment "Hadron is a subatomic particle which experiences the strong force." ;
rdfs:subClassOf obo:CHEBI_36343 .
obo:WBls_0000032 a rdfs:Class ;
rdfs:label "dauer larva Ce" ;
rdfs:comment "A third stage larva specialized for dispersal and long term survival." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000817 .
obo:GO_0008213 a rdfs:Class ;
rdfs:label "protein alkylation" ;
rdfs:comment "The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom." ;
rdfs:subClassOf obo:GO_0036211 .
obo:WBPhenotype_0001780 a rdfs:Class ;
rdfs:label "associative learning variant" ;
rdfs:comment "Variations in the behavioral plasticity induced by the integration of two sensory signals compared to control. In C. elegans animals exhibit enhancement of butanone chemotaxis by preexposure to butanone and food." ;
rdfs:subClassOf obo:WBPhenotype_0000517 , obo:WBPhenotype_0000738 .
obo:WBPhenotype_0000553 a rdfs:Class ;
rdfs:label "muscle birefringence variant" ;
rdfs:comment "Animals exhibit a weak and abnormal birefringency pattern in muscle fibers when examined using polarized optics." ;
rdfs:subClassOf obo:WBPhenotype_0000926 .
obo:WBPhenotype_0002475 a rdfs:Class ;
rdfs:label "pharynx length variant" ;
rdfs:comment "Animals vary in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000709 .
obo:WBPhenotype_0000834 a rdfs:Class ;
rdfs:label "E lineage variant" ;
rdfs:comment "The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000824 .
obo:CHEBI_33791 a rdfs:Class ;
rdfs:label "canonical nucleoside residue" ;
rdfs:subClassOf obo:CHEBI_50320 .
obo:CHEBI_38166 a rdfs:Class ;
rdfs:label "organic heteropolycyclic compound" ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33671 .
obo:CHEBI_33655 a rdfs:Class ;
rdfs:label "aromatic compound" ;
rdfs:comment "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekulé structure) is said to possess aromatic character." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:PATO_0000956 a rdfs:Class ;
rdfs:label "sterile" ;
rdfs:comment "A fertility quality inhering in a bearer by virtue of the bearer's being incapable of initiating, sustaining, or supporting reproduction." ;
rdfs:subClassOf obo:PATO_0000274 .
obo:WBPhenotype_0002636 a rdfs:Class ;
rdfs:label "detachment of chromatin from nuclear periphery"@en ;
rdfs:comment "One or more cells of the animal exhibit chromatin that has become detached from the nuclear periphery, unlike controls." ;
rdfs:subClassOf obo:WBPhenotype_0002542 .
obo:GO_0048842 a rdfs:Class ;
rdfs:label "positive regulation of axon extension involved in axon guidance" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance." ;
rdfs:subClassOf obo:GO_0045773 , obo:GO_0048841 , obo:GO_0050921 , obo:GO_0065007 .
obo:WBPhenotype_0001248 a rdfs:Class ;
rdfs:label "wing cilia morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of the microtuble-based projections that in control animals invaginate individually into the sheath cell of the neuronal sensillum rather than projecting through the socket cell to the outside. In C. elegans, the cilia of each wing cell has its own unique shape and as they are not exposed to the outside, they do not typically take up dyes." ;
rdfs:subClassOf obo:WBPhenotype_0000615 .
obo:GO_0045664 a rdfs:Class ;
rdfs:label "regulation of neuron differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuron differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:WBbt_0005214 a rdfs:Class ;
rdfs:label "dorsal ganglion" ;
rdfs:comment "ganglion that lies beside the nerve ring in the head. It contains neuron cell bodies that send their neuronal processes into the ring and longitudinal nerves, but form no local neuropil separate from the nerve ring. The dorsal ganglion is in close contact with the dorsal hypodermal cord." ;
rdfs:subClassOf obo:WBbt_0005135 .
obo:GO_0098542 a rdfs:Class ;
rdfs:label "defense response to other organism" ;
rdfs:comment "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." ;
rdfs:subClassOf obo:GO_0006952 , obo:GO_0051707 .
obo:GO_1905939 a rdfs:Class ;
rdfs:label "regulation of gonad development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gonad development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 , obo:GO_2000241 .
obo:WBPhenotype_0001654 a rdfs:Class ;
rdfs:label "cadmium resistant" ;
rdfs:comment "Animals fail to respond to the concentration of cadmium that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to cadmium to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001653 .
obo:WBPhenotype_0002170 a rdfs:Class ;
rdfs:label "calcium mediated signaling variant" ;
rdfs:comment "Any variation in the series of molecular signals in which a cell or tissue uses calcium ions to convert a signal into a response, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:CHEBI_38275 a rdfs:Class ;
rdfs:label "pyrrolidinone" ;
rdfs:subClassOf obo:CHEBI_38260 .
obo:WBbt_0007832 a rdfs:Class ;
rdfs:label "cuticular ala" ;
rdfs:comment "Small linear ridges running along the lateral lines of the cuticle, lengthwise along the body; these thickenings lie in register with the seam cells which likely produce them and are present in the cuticle of the L1, dauer and adult stages, but not in other larval stages. The alae are suspected to provide better traction when the animal generates a bodywave. Since the animal usually lies on its side, the alae are in perfect position to catch against the substrate." ;
rdfs:subClassOf obo:WBbt_0005732 .
obo:GO_0071482 a rdfs:Class ;
rdfs:label "cellular response to light stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." ;
rdfs:subClassOf obo:GO_0009416 , obo:GO_0071478 .
obo:WBPhenotype_0001765 a rdfs:Class ;
rdfs:label "carbon dioxide avoidance variant" ;
rdfs:comment "Variations in the characteristic movement away from specific CO2 levels compared to control. C. elegans avoids high levels of CO2." ;
rdfs:subClassOf obo:WBPhenotype_0001764 .
obo:GO_0051049 a rdfs:Class ;
rdfs:label "regulation of transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032879 , obo:GO_0065007 .
obo:WBPhenotype_0001180 a rdfs:Class ;
rdfs:label "accumulated germline cell corpses" ;
rdfs:comment "Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed." ;
rdfs:subClassOf obo:WBPhenotype_0000241 .
obo:WBPhenotype_0000141 a rdfs:Class ;
rdfs:label "stress induced lethality increased" ;
rdfs:comment "Animal populations exhibit a further decrease in survival when exposed to stress stimuli compared to the lethality rate observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000139 .
obo:WBPhenotype_0002353 a rdfs:Class ;
rdfs:label "tRNA expression decreased" ;
rdfs:comment "Animals exhibit reduced levels of transfer RNA compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000134 .
obo:CHEBI_22562 a rdfs:Class ;
rdfs:label "anilines" ;
rdfs:comment "Any aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_33860 .
obo:GO_1905902 a rdfs:Class ;
rdfs:label "regulation of mesoderm formation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mesoderm formation." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0045087 a rdfs:Class ;
rdfs:label "innate immune response" ;
rdfs:comment "Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." ;
rdfs:subClassOf obo:GO_0006955 , obo:GO_0140546 .
obo:GO_0009891 a rdfs:Class ;
rdfs:label "positive regulation of biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0009893 , obo:GO_0065007 .
obo:GO_0048070 a rdfs:Class ;
rdfs:label "regulation of developmental pigmentation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120305 .
obo:GO_0007498 a rdfs:Class ;
rdfs:label "mesoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." ;
rdfs:subClassOf obo:GO_0009888 .
obo:WBPhenotype_0008002 a rdfs:Class ;
rdfs:label "embryonic somatic cell fate specification variant" ;
rdfs:comment "Any variation in the processes that govern acquisition of somatic cell fates in the embryo, from the time of zygote formation until hatching compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0008001 .
obo:GO_0061014 a rdfs:Class ;
rdfs:label "positive regulation of mRNA catabolic process" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0061013 , obo:GO_0065007 , obo:GO_1903313 .
obo:GO_0009611 a rdfs:Class ;
rdfs:label "response to wounding" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism." ;
rdfs:subClassOf obo:GO_0006950 .
obo:CHEBI_21731 a rdfs:Class ;
rdfs:label "N-glycosyl compound" ;
rdfs:comment "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond." ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_63161 .
obo:GO_0072665 a rdfs:Class ;
rdfs:label "protein localization to vacuole" ;
rdfs:comment "A process in which a protein is transported to, or maintained at, a location in a vacuole." ;
rdfs:subClassOf obo:GO_0033365 .
obo:WBPhenotype_0001788 a rdfs:Class ;
rdfs:label "resistant to mutagens" ;
rdfs:comment "Animals survive longer than control animals after or during exposure to DNA damaging agents." ;
rdfs:subClassOf obo:WBPhenotype_0000739 .
obo:WBPhenotype_0002607 a rdfs:Class ;
rdfs:label "nuclear size abnormal"@en ;
rdfs:comment "One or more cellular nuclei exhibit an abnormal size, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001028 .
obo:GO_0055115 a rdfs:Class ;
rdfs:label "entry into diapause" ;
rdfs:comment "The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." ;
rdfs:subClassOf obo:GO_0022611 .
obo:WBPhenotype_0000672 a rdfs:Class ;
rdfs:label "presynaptic vesicle cluster localization variant" ;
rdfs:comment "Animals display variations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000102 .
obo:WBPhenotype_0001034 a rdfs:Class ;
rdfs:label "pronuclear nuclear appearance defective early emb" ;
rdfs:comment "The morphology of pronuclei and nuclei are defective in the early embryo. In C. elegans, this defect is often characterized by pronuclei and nuclei that are small or missing altogether and are often accompanied by spindle defects." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0001374 .
obo:WBPhenotype_0000146 a rdfs:Class ;
rdfs:label "organism temperature response variant" ;
rdfs:comment "Animals do not respond to changes in temperature or thermal stress in the same manner as control animals. In C.elegans this is often measured by changes in the expression of stress proteins or changes in life span." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBPhenotype_0001372 a rdfs:Class ;
rdfs:label "protein DNA interaction variant" ;
rdfs:comment "Variations in the selective and non-covalent physical association between a protein and a specific DNA sequence, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001369 .
obo:WBPhenotype_0001074 a rdfs:Class ;
rdfs:label "vulval muscle unresponsive to serotonin" ;
rdfs:comment "The vulval muscle does not respond to serotonin in the same manner as control animals. This phenotype is often assayed by imaging of calcium transients in response to serotonin." ;
rdfs:subClassOf obo:WBPhenotype_0001068 , obo:WBPhenotype_0001076 .
obo:WBPhenotype_0001215 a rdfs:Class ;
rdfs:label "germ cell mitosis variant" ;
rdfs:comment "Variations in the mitotic expansion of germ cell populations or in the appearance of nuclei during development in the premeiotic region of the germline compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000823 .
obo:GO_0007039 a rdfs:Class ;
rdfs:label "protein catabolic process in the vacuole" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." ;
rdfs:subClassOf obo:GO_0030163 .
obo:WBPhenotype_0000199 a rdfs:Class ;
rdfs:label "male tail sensory ray development variant" ;
rdfs:comment "Any variation in the progression of the finger-like sensory sensilla that project from the tail and embed in the male fan from its formation to the mature structure when compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000930 , obo:WBPhenotype_0001008 .
obo:GO_0044786 a rdfs:Class ;
rdfs:label "cell cycle DNA replication" ;
rdfs:comment "The DNA-dependent DNA replication that takes place as part of the cell cycle." ;
rdfs:subClassOf obo:GO_0006261 , obo:GO_0022402 .
obo:WBPhenotype_0001356 a rdfs:Class ;
rdfs:label "male sex muscle morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the muscles of the adult male reproductive system compared to control. In C. elegans males, the M myoblast gives rise to a much larger set of specialized muscles, compared to hermaphrodites, which differentiate within the tail region (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001024 .
obo:GO_0060102 a rdfs:Class ;
rdfs:label "cuticular extracellular matrix" ;
rdfs:comment "A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans." ;
rdfs:subClassOf obo:GO_0140047 .
obo:WBPhenotype_0002362 a rdfs:Class ;
rdfs:label "protein sumoylation variant" ;
rdfs:comment "Variations in the process by which one or more SUMO moieties are added to a protein, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001382 .
obo:WBbt_0003672 a rdfs:Class ;
rdfs:label "epithelial cell" ;
rdfs:comment "cell of epithelium, the layer of cells that cover the external surface of an organism as well as forming an inner lining between the tissues and organs of that organism and the external environment. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_0051351 a rdfs:Class ;
rdfs:label "positive regulation of ligase activity" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate." ;
rdfs:subClassOf obo:GO_0043085 , obo:GO_0065007 .
obo:CHEBI_63726 a rdfs:Class ;
rdfs:label "neuroprotective agent" ;
rdfs:comment "Any compound that can be used for the treatment of neurodegenerative disorders." ;
rdfs:subClassOf obo:CHEBI_50267 .
obo:GO_1904356 a rdfs:Class ;
rdfs:label "regulation of telomere maintenance via telomere lengthening" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening." ;
rdfs:subClassOf obo:GO_0032204 , obo:GO_0065007 .
obo:GO_0035295 a rdfs:Class ;
rdfs:label "tube development" ;
rdfs:comment "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." ;
rdfs:subClassOf obo:GO_0048856 .
obo:WBPhenotype_0002547 a rdfs:Class ;
rdfs:label "gut Enterobacteriaceae bloom"@en ;
rdfs:comment "Animals exhibit a greater abundance of bacteria of the Enterobacteriaceae family in the gut, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002546 .
obo:WBPhenotype_0002468 a rdfs:Class ;
rdfs:label "translation rate reduced" ;
rdfs:comment "Animals exhibit a reduction in the rate of the chemical reactions and pathways resulting in the formation of a protein, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000121 .
obo:CHEBI_27363 a rdfs:Class ;
rdfs:label "zinc atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33340 .
obo:GO_0007020 a rdfs:Class ;
rdfs:label "microtubule nucleation" ;
rdfs:comment "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." ;
rdfs:subClassOf obo:GO_0000226 .
obo:WBPhenotype_0000639 a rdfs:Class ;
rdfs:label "temperature induced dauer formation variant" ;
rdfs:comment "Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C." ;
rdfs:subClassOf obo:WBPhenotype_0000146 , obo:WBPhenotype_0001539 .
obo:GO_2001252 a rdfs:Class ;
rdfs:label "positive regulation of chromosome organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chromosome organization." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0033044 , obo:GO_0065007 .
obo:WBPhenotype_0001260 a rdfs:Class ;
rdfs:label "oocyte morphology variant" ;
rdfs:comment "Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000900 .
obo:GO_1903430 a rdfs:Class ;
rdfs:label "negative regulation of cell maturation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0065007 , obo:GO_1903429 .
obo:CHEBI_76895 a rdfs:Class ;
rdfs:label "EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor" ;
rdfs:comment "An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*)." ;
rdfs:subClassOf obo:CHEBI_73216 .
obo:GO_0031672 a rdfs:Class ;
rdfs:label "A band" ;
rdfs:comment "The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_64365 a rdfs:Class ;
rdfs:label "aralkylamino compound" ;
rdfs:comment "An organic amino compound in which an aminoalkyl group is linked to an arene." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:WBPhenotype_0001652 a rdfs:Class ;
rdfs:label "anchor cell invasion variant" ;
rdfs:comment "Any variation in the process by which the gonad anchor cell makes contact with vulval cells in order to create a uterine-vulval connection. In C. elegans, this includes the loss of the basement membranes between these cells and the crossing of the basolateral portion of the anchor cell through this gap." ;
rdfs:subClassOf obo:WBPhenotype_0000283 .
obo:GO_0097190 a rdfs:Class ;
rdfs:label "apoptotic signaling pathway" ;
rdfs:comment "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." ;
rdfs:subClassOf obo:GO_0007165 .
obo:CHEBI_76815 a rdfs:Class ;
rdfs:label "EC 2.7.7.* (nucleotidyltransferase) inhibitor" ;
rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*)." ;
rdfs:subClassOf obo:CHEBI_76668 .
obo:CHEBI_35476 a rdfs:Class ;
rdfs:label "antipsychotic agent" ;
rdfs:comment "Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect." ;
rdfs:subClassOf obo:CHEBI_35473 .
obo:WBPhenotype_0002642 a rdfs:Class ;
rdfs:label "chemical accumulation abnormal"@en ;
rdfs:comment "Animals exposed to an exogenous chemical exhibit an abnormal accumulation of this chemical in the body of the animals, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:CHEBI_17972 a rdfs:Class ;
rdfs:label "ribonucleoside triphosphate" ;
rdfs:subClassOf obo:CHEBI_17326 .
obo:WBPhenotype_0000661 a rdfs:Class ;
rdfs:label "solitary feeding increased" ;
rdfs:comment "Animals disperse across a bacterial lawn and feed alone. When food is limiting, they can aggregate into swarms or clumps, but disperse once again when food is absent." ;
rdfs:subClassOf obo:WBPhenotype_0000659 , obo:WBPhenotype_0001291 .
obo:WBbt_0005451 a rdfs:Class ;
rdfs:label "pharyngeal muscle cell" ;
rdfs:comment "type of cells that make up muscle layers in the pharynx." ;
rdfs:subClassOf obo:WBbt_0005460 , obo:WBbt_0005820 .
obo:WBbt_0005752 a rdfs:Class ;
rdfs:label "Sex specific entity" ;
rdfs:comment "anatomical or cell objects that exist in only one, male or hermaphrodite, sex." ;
rdfs:subClassOf obo:WBbt_0005763 .
obo:WBPhenotype_0001708 a rdfs:Class ;
rdfs:label "protein export from nucleus defective" ;
rdfs:comment "The directed movement of a protein from the nucleus into the cytoplasm is impaired." ;
rdfs:subClassOf obo:WBPhenotype_0001706 .
obo:WBPhenotype_0001695 a rdfs:Class ;
rdfs:label "glycosyltransferase activity variant" ;
rdfs:comment "Animals exhibit variations in their catalytic ability the transfer glycolsyl groups from one compound (donor) to another (acceptor) often measured by a reduction in the amount of glycosylated products compared to that observed in control animals of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0000733 .
obo:GO_0101024 a rdfs:Class ;
rdfs:label "mitotic nuclear membrane organization" ;
rdfs:comment "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis." ;
rdfs:subClassOf obo:GO_0071763 , obo:GO_1903047 .
obo:GO_1904576 a rdfs:Class ;
rdfs:label "obsolete response to tunicamycin" ;
rdfs:comment "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus." .
obo:GO_0048521 a rdfs:Class ;
rdfs:label "negative regulation of behavior" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ;
rdfs:subClassOf obo:GO_0050795 , obo:GO_0051241 , obo:GO_0065007 .
obo:PATO_0000069 a rdfs:Class ;
rdfs:label "deviation (from_normal)" ;
rdfs:comment "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." ;
rdfs:subClassOf obo:PATO_0000068 .
obo:WBPhenotype_0000879 a rdfs:Class ;
rdfs:label "telomere length regulation variant" ;
rdfs:comment "Animals exhibit variations in the processes that are required to maintain the length of telomeric DNA from generation to generation compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001673 .
obo:WBPhenotype_0001562 a rdfs:Class ;
rdfs:label "dauer outer labial sensillum variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum." ;
rdfs:subClassOf obo:WBPhenotype_0001533 , obo:WBPhenotype_0001557 .
obo:GO_0099643 a rdfs:Class ;
rdfs:label "signal release from synapse" ;
rdfs:comment "Any signal release from a synapse." ;
rdfs:subClassOf obo:GO_0023061 .
obo:WBPhenotype_0000016 a rdfs:Class ;
rdfs:label "aldicarb hypersensitive" ;
rdfs:comment "Animals respond to aldicarb at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000500 , obo:WBPhenotype_0000680 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001912 a rdfs:Class ;
rdfs:label "fewer coelomocytes" ;
rdfs:comment "The number of coelomocytes are reduced compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds." ;
rdfs:subClassOf obo:WBPhenotype_0000618 , obo:WBPhenotype_0002174 .
obo:WBPhenotype_0001383 a rdfs:Class ;
rdfs:label "protein methylation variant" ;
rdfs:comment "Variations in the processes that incorporate methyl groups to one or more amino acids within a protein, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001382 .
obo:GO_0070126 a rdfs:Class ;
rdfs:label "mitochondrial translational termination" ;
rdfs:comment "The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa)." ;
rdfs:subClassOf obo:GO_0006415 .
obo:GO_0009605 a rdfs:Class ;
rdfs:label "response to external stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." ;
rdfs:subClassOf obo:GO_0050896 .
obo:WBPhenotype_0001536 a rdfs:Class ;
rdfs:label "embryonic cell patterning variant" ;
rdfs:comment "Embryos exhibit variations in the patterning of differentiated cell types, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000050 .
obo:WBPhenotype_0002645 a rdfs:Class ;
rdfs:label "thermorecovery abnormal"@en ;
rdfs:comment "Animals exhibit an abnormal recovery from heat stress, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000146 .
obo:GO_0120032 a rdfs:Class ;
rdfs:label "regulation of plasma membrane bounded cell projection assembly" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly." ;
rdfs:subClassOf obo:GO_0060491 , obo:GO_0065007 , obo:GO_0120035 .
obo:WBPhenotype_0001940 a rdfs:Class ;
rdfs:label "rachis morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis." ;
rdfs:subClassOf obo:WBPhenotype_0001355 .
obo:GO_2000294 a rdfs:Class ;
rdfs:label "positive regulation of defecation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of defecation." ;
rdfs:subClassOf obo:GO_0051047 , obo:GO_0060456 , obo:GO_0065007 , obo:GO_2000292 .
obo:GO_0007588 a rdfs:Class ;
rdfs:label "excretion" ;
rdfs:comment "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." ;
rdfs:subClassOf obo:GO_0003008 .
obo:CHEBI_77746 a rdfs:Class ;
rdfs:label "human metabolite" ;
rdfs:comment "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." ;
rdfs:subClassOf obo:CHEBI_75768 .
obo:WBPhenotype_0000184 a rdfs:Class ;
rdfs:label "apoptosis fails to occur" ;
rdfs:comment "Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes." ;
rdfs:subClassOf obo:WBPhenotype_0000182 .
obo:GO_0000086 a rdfs:Class ;
rdfs:label "G2/M transition of mitotic cell cycle" ;
rdfs:comment "The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex." ;
rdfs:subClassOf obo:GO_0044772 , obo:GO_0044839 .
obo:GO_0006412 a rdfs:Class ;
rdfs:label "translation" ;
rdfs:comment "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." ;
rdfs:subClassOf obo:GO_0009059 , obo:GO_0019538 .
obo:WBPhenotype_0001404 a rdfs:Class ;
rdfs:label "ectopic expression antibody" ;
rdfs:comment "Any variation that results in the detection of protein expression in cells/tissues through antibody staining, that is otherwise not observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000424 .
obo:WBPhenotype_0000135 a rdfs:Class ;
rdfs:label "gene expression level high" ;
rdfs:comment "Animals exhibit an increase in the intensity of expression of a gene product compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002575 .
obo:CHEBI_47804 a rdfs:Class ;
rdfs:label "dibenzoazepine" ;
rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38101 .
obo:WBbt_0008447 a rdfs:Class ;
rdfs:label "somatic blastomere" ;
rdfs:comment "Embryonic cell which descends from the same parent cell as a germline blastomere." ;
rdfs:subClassOf obo:WBbt_0007028 .
obo:WBbt_0005364 a rdfs:Class ;
rdfs:label "anus" ;
rdfs:comment "openning of the rectum" ;
rdfs:subClassOf obo:WBbt_0005732 .
obo:GO_1903311 a rdfs:Class ;
rdfs:label "regulation of mRNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051252 , obo:GO_0065007 .
obo:WBPhenotype_0001529 a rdfs:Class ;
rdfs:label "obsolete sensilium sheath cell variant" ;
rdfs:comment "OBSOLETE: Any variation in the form, structure or composition of an interfacial epithelial cell which forms a specialized environment surrounding the ciliated sensory ending(s) of one or more neurons and is often accompanied by a more distal socket cell compared to control (Wormatlas)." .
obo:WBPhenotype_0000612 a rdfs:Class ;
rdfs:label "nervous system physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the nervous system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000575 .
obo:WBPhenotype_0001725 a rdfs:Class ;
rdfs:label "cellular osmotic stress response variant" ;
rdfs:comment "Cells exhibit variations in the response to osmotic stress compared to control. In C. elegans, exposure to stress-inducing osmotic conditions invokes cellular changes, including transcriptional up or down-regulation of genes." ;
rdfs:subClassOf obo:WBPhenotype_0000142 , obo:WBPhenotype_0000523 , obo:WBPhenotype_0000876 .
obo:CHEBI_82680 a rdfs:Class ;
rdfs:label "monounsaturated fatty acid anion" ;
rdfs:comment "Any unsaturated fatty acid anion with one double or triple bond in the fatty acid chain." ;
rdfs:subClassOf obo:CHEBI_2580 .
obo:GO_0010948 a rdfs:Class ;
rdfs:label "negative regulation of cell cycle process" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0045786 , obo:GO_0065007 .
obo:GO_0005879 a rdfs:Class ;
rdfs:label "axonemal microtubule" ;
rdfs:comment "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." ;
rdfs:subClassOf obo:GO_0005874 , obo:GO_0005881 .
obo:CHEBI_25901 a rdfs:Class ;
rdfs:label "pentose" ;
rdfs:comment "A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose)." ;
rdfs:subClassOf obo:CHEBI_35381 .
obo:WBPhenotype_0001844 a rdfs:Class ;
rdfs:label "lipid hydrolysis regulation variant" ;
rdfs:comment "Variations in the process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000725 .
obo:WBPhenotype_0002380 a rdfs:Class ;
rdfs:label "neuron degeneration enhanced" ;
rdfs:comment "Neurons undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles at a faster rate or greater extent than those under conditions that elicit this response in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000636 .
obo:WBPhenotype_0000652 a rdfs:Class ;
rdfs:label "sensory system variant" ;
rdfs:comment "Variations in the progression of a set of interacting or interdependent entities forming the sensory system over time from an initial condition to a later condition compared to control animals. The sensory system is involved in the perception of a stimuli, its conversion into a signal and the recognition and characterization of the resulting signal." ;
rdfs:subClassOf obo:WBPhenotype_0000612 .
obo:WBPhenotype_0000679 a rdfs:Class ;
rdfs:label "transgene subcellular localization variant" ;
rdfs:comment "Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000961 .
obo:WBPhenotype_0001736 a rdfs:Class ;
rdfs:label "acetate chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to acetate compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000015 .
obo:WBPhenotype_0000152 a rdfs:Class ;
rdfs:label "no cleavage furrow first division early emb" ;
rdfs:comment "One-cell embryos do not form the shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ;
rdfs:subClassOf obo:WBPhenotype_0001129 .
obo:GO_0005818 a rdfs:Class ;
rdfs:label "aster" ;
rdfs:comment "An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores." ;
rdfs:subClassOf obo:GO_0043232 , obo:GO_0099080 .
obo:WBPhenotype_0002422 a rdfs:Class ;
rdfs:label "tunicamycin resistant" ;
rdfs:comment "Animals respond to tunicamycin at a higher concentration or a longer exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000359 , obo:WBPhenotype_0001502 .
obo:CHEBI_39218 a rdfs:Class ;
rdfs:label "macrolide acaricide" ;
rdfs:subClassOf obo:CHEBI_39221 .
obo:WBPhenotype_0001985 a rdfs:Class ;
rdfs:label "short range axon migration variant" ;
rdfs:comment "Animals exhibit axons with migration behaviors that differ from those observed in control animals before the axons reach a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords." ;
rdfs:subClassOf obo:WBPhenotype_0001224 .
obo:BFO_0000002 a rdfs:Class ;
rdfs:label "continuant"@en ;
rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
rdfs:subClassOf obo:BFO_0000001 .
obo:CHEBI_33248 a rdfs:Class ;
rdfs:label "hydrocarbyl group" ;
rdfs:comment "A univalent group formed by removing a hydrogen atom from a hydrocarbon." ;
rdfs:subClassOf obo:CHEBI_33249 .
obo:CHEBI_26952 a rdfs:Class ;
rdfs:label "thioacetic acid" ;
rdfs:subClassOf obo:CHEBI_35737 .
obo:WBPhenotype_0000229 a rdfs:Class ;
rdfs:label "small" ;
rdfs:comment "Animals are shorter and thinner than control animals at the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0001726 , obo:WBPhenotype_0001727 , obo:WBPhenotype_0002555 .
obo:CHEBI_32565 a rdfs:Class ;
rdfs:label "lysinium(2+)" ;
rdfs:comment "An α-amino-acid cation obtained by protonation of both amino groups of lysine." ;
rdfs:subClassOf obo:CHEBI_33719 .
obo:WBPhenotype_0002558 a rdfs:Class ;
rdfs:label "extracellular component phenotype"@en ;
rdfs:comment "A phenotype affecting a particular extracellular component." ;
rdfs:subClassOf obo:WBPhenotype_0002551 .
obo:CHEBI_73216 a rdfs:Class ;
rdfs:label "EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor" ;
rdfs:comment "Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*)." ;
rdfs:subClassOf obo:CHEBI_76759 .
obo:WBbt_0003675 a rdfs:Class ;
rdfs:label "muscle cell" ;
rdfs:comment "Contractile cell that makes up muscle tissue." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_0022403 a rdfs:Class ;
rdfs:label "cell cycle phase" ;
rdfs:comment "One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ;
rdfs:subClassOf obo:GO_0044848 .
obo:WBPhenotype_0002577 a rdfs:Class ;
rdfs:label "basement membrane composition phenotype"@en ;
rdfs:comment "Animals exhibit variations in the composition of basement membranes, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002588 .
obo:CHEBI_35545 a rdfs:Class ;
rdfs:label "bipyridine" ;
rdfs:subClassOf obo:CHEBI_50511 .
obo:GO_1902229 a rdfs:Class ;
rdfs:label "regulation of intrinsic apoptotic signaling pathway in response to DNA damage" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080135 , obo:GO_2001242 .
obo:WBPhenotype_0000094 a rdfs:Class ;
rdfs:label "anus development variant" ;
rdfs:comment "Any variation in the progression of the caudal opening of the rectum in the tail over time compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000617 .
obo:WBPhenotype_0000935 a rdfs:Class ;
rdfs:label "D lineage variant" ;
rdfs:comment "The descendants of the D blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000824 .
obo:GO_0000070 a rdfs:Class ;
rdfs:label "mitotic sister chromatid segregation" ;
rdfs:comment "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." ;
rdfs:subClassOf obo:GO_0000819 , obo:GO_0098813 , obo:GO_1903047 .
obo:GO_0014076 a rdfs:Class ;
rdfs:label "response to fluoxetine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor." ;
rdfs:subClassOf obo:GO_0036276 .
obo:CHEBI_36921 a rdfs:Class ;
rdfs:label "antimony oxoanion" ;
rdfs:subClassOf obo:CHEBI_24834 , obo:CHEBI_33459 , obo:CHEBI_50007 .
obo:CHEBI_55324 a rdfs:Class ;
rdfs:label "gastrointestinal drug" ;
rdfs:comment "A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:CHEBI_33559 a rdfs:Class ;
rdfs:label "s-block element atom" ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:CHEBI_88188 a rdfs:Class ;
rdfs:label "drug allergen" ;
rdfs:comment "Any drug which causes the onset of an allergic reaction." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_50904 .
obo:WBPhenotype_0000373 a rdfs:Class ;
rdfs:label "egg shape variable" ;
rdfs:comment "The overall structure or appearance of fertilized oocytes that are laid exhibit nonconsistent and significant deviation from that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000037 .
obo:WBPhenotype_0000924 a rdfs:Class ;
rdfs:label "striated muscle morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the striated muscle compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000904 .
obo:WBPhenotype_0001345 a rdfs:Class ;
rdfs:label "cytoskeleton organization biogenesis variant" ;
rdfs:comment "Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." ;
rdfs:subClassOf obo:WBPhenotype_0000519 , obo:WBPhenotype_0001344 .
obo:CHEBI_36357 a rdfs:Class ;
rdfs:label "polyatomic entity" ;
rdfs:comment "Any molecular entity consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:WBPhenotype_0001135 a rdfs:Class ;
rdfs:label "embryonic morphology defective early emb" ;
rdfs:comment "Animals exhibit defects in the form, structure or composition of any of its parts during the early embryonic stage." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0001136 .
obo:WBPhenotype_0000485 a rdfs:Class ;
rdfs:label "dauer death increased" ;
rdfs:comment "The survival of animals in the alternative larval stage which they enter when placed under conditions of environmental stress is reduced." ;
rdfs:subClassOf obo:WBPhenotype_0002527 .
obo:CHEBI_24632 a rdfs:Class ;
rdfs:label "hydrocarbon" ;
rdfs:comment "A compound consisting of carbon and hydrogen only." ;
rdfs:subClassOf obo:CHEBI_33245 .
obo:GO_0090224 a rdfs:Class ;
rdfs:label "regulation of spindle organization" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0065007 , obo:GO_0070507 .
obo:GO_0000794 a rdfs:Class ;
rdfs:label "condensed nuclear chromosome" ;
rdfs:comment "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome." ;
rdfs:subClassOf obo:GO_0000228 , obo:GO_0000793 .
obo:CHEBI_37578 a rdfs:Class ;
rdfs:label "halide" ;
rdfs:comment "Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements." ;
rdfs:subClassOf obo:CHEBI_24471 , obo:CHEBI_37577 .
obo:CHEBI_35273 a rdfs:Class ;
rdfs:label "quaternary ammonium salt" ;
rdfs:comment "Derivatives of ammonium compounds, (NH4+)Y−, in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." ;
rdfs:subClassOf obo:CHEBI_26469 , obo:CHEBI_46850 .
obo:CHEBI_6078 a rdfs:Class ;
rdfs:label "ivermectin" ;
rdfs:comment "A mixture consisting of ≥ 90% 22,23-dihydroavermectin B1a (R = Me) and ≤ 10% 22,23-dihydroavermectin B1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_60004 .
obo:CHEBI_38325 a rdfs:Class ;
rdfs:label "muscarinic agonist" ;
rdfs:comment "Any drug that binds to and activates a muscarinic cholinergic receptor." ;
rdfs:subClassOf obo:CHEBI_38324 .
obo:CHEBI_35987 a rdfs:Class ;
rdfs:label "diamino acid" ;
rdfs:comment "Any amino acid carrying two amino groups." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:CHEBI_64775 a rdfs:Class ;
rdfs:label "organic anionic group" ;
rdfs:comment "An anionic group that contains carbon." ;
rdfs:subClassOf obo:CHEBI_64767 .
obo:WBPhenotype_0002367 a rdfs:Class ;
rdfs:label "non-living barrier escape defective" ;
rdfs:comment "Animals are less successful than controls in extracting themselves from mesh or other non-living obstructing obstacles." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:WBPhenotype_0001475 a rdfs:Class ;
rdfs:label "trimethylthiazole chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of trimethylthiazole. In C. elegans, at specific concentrations, trimethylthiazole is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0000265 .
obo:CHEBI_83811 a rdfs:Class ;
rdfs:label "proteinogenic amino acid derivative" ;
rdfs:comment "Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom." ;
rdfs:subClassOf obo:CHEBI_83821 .
obo:GO_1904514 a rdfs:Class ;
rdfs:label "positive regulation of initiation of premeiotic DNA replication" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication." ;
rdfs:subClassOf obo:GO_0010571 , obo:GO_0032298 , obo:GO_0065007 , obo:GO_1904512 , obo:GO_2000243 .
obo:WBbt_0008587 a rdfs:Class ;
rdfs:label "egg-laying apparatus" ;
rdfs:comment "An apparatus for laying eggs of the hermaphrodite reproductive system, consists of the uterus, the uterine muscles, the vulva, the vulval muscles, and a local neuropil formed by the egg-laying neurons." ;
rdfs:subClassOf obo:WBbt_0008422 .
obo:CL_0000540 a rdfs:Class ;
rdfs:label "neuron" ;
rdfs:comment "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." ;
rdfs:subClassOf obo:CL_0000393 , obo:CL_0000404 , obo:CL_0002319 .
obo:RO_0002100 a rdf:Property ;
rdfs:label "has soma location"@en ;
rdfs:comment "Relation between a neuron and a material anatomical entity that its soma is part of."@en ;
rdfs:domain obo:CL_0000540 ;
rdfs:range obo:UBERON_0000465 ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0020104 a rdf:Property ;
rdfs:label "is neuron" ;
rdfs:comment "This property only applies to neurons" ;
rdfs:domain obo:CL_0000540 ;
rdfs:range .
obo:CHEBI_26034 a rdfs:Class ;
rdfs:label "phosphatidylinositol 3-phosphate" ;
rdfs:comment "A phosphatidylinositol monophosphate carrying the phosphate group at the 3-position." ;
rdfs:subClassOf obo:CHEBI_26036 .
obo:CHEBI_48539 a rdfs:Class ;
rdfs:label "alpha-adrenergic drug" ;
rdfs:comment "Any drug that acts on an α-adrenergic receptor." ;
rdfs:subClassOf obo:CHEBI_37962 .
obo:WBPhenotype_0001631 a rdfs:Class ;
rdfs:label "nullo X gamete" ;
rdfs:comment "Animals produce ova/sperm that contain no X chromosome in a nonmendelian segregation pattern." ;
rdfs:subClassOf obo:WBPhenotype_0001664 .
obo:WBPhenotype_0002273 a rdfs:Class ;
rdfs:label "dietary sugar response variant" ;
rdfs:comment "Animals exhibit enhanced negative effects on growth, health, development or metabolism, in response to dietary sugar-rich diets, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002525 .
obo:WBPhenotype_0002626 a rdfs:Class ;
rdfs:label "attachment to substrate abnormal"@en ;
rdfs:comment "Animals exhibit an abnormal attachment (or lack thereof) to a substrate, compared to controls. For some parasitic worms, attachment to host tissue surfaces, like endothelium, is a necessary behavior for their life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000576 .
obo:WBPhenotype_0001175 a rdfs:Class ;
rdfs:label "high incidence male progeny" ;
rdfs:comment "Higher numbers of male progeny occur in the population compared to control populations. In C. elegans, the high incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an increase in X chromosome nondisjunction." ;
rdfs:subClassOf obo:WBPhenotype_0001664 .
obo:CHEBI_29256 a rdfs:Class ;
rdfs:label "thiol" ;
rdfs:comment "An organosulfur compound in which a thiol group, ‒SH, is attached to a carbon atom of any aliphatic or aromatic moiety." ;
rdfs:subClassOf obo:CHEBI_33261 .
obo:PATO_0002324 a rdfs:Class ;
rdfs:label "offset quality" ;
rdfs:comment "The temporal relation between the end of the process with respect to a reference process." ;
rdfs:subClassOf obo:PATO_0002323 .
obo:CHEBI_59202 a rdfs:Class ;
rdfs:label "straight-chain fatty acid" ;
rdfs:comment "Any fatty acid whose skeletal carbon atoms form an unbranched open chain." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:WBPhenotype_0002402 a rdfs:Class ;
rdfs:label "cell position defective" ;
rdfs:comment "A cell (or group of cells) is not found in the correct body position compared the placement in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000533 .
obo:GO_0043226 a rdfs:Class ;
rdfs:label "organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0023057 a rdfs:Class ;
rdfs:label "negative regulation of signaling" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." ;
rdfs:subClassOf obo:GO_0023051 , obo:GO_0048519 , obo:GO_0065007 .
obo:GO_0060100 a rdfs:Class ;
rdfs:label "positive regulation of phagocytosis, engulfment" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ;
rdfs:subClassOf obo:GO_0050766 , obo:GO_0060099 , obo:GO_0065007 , obo:GO_1905155 .
obo:WBPhenotype_0001665 a rdfs:Class ;
rdfs:label "low incidence male progeny" ;
rdfs:comment "Lower numbers of male progeny occur in the population compared to control populations. In C. elegans, the low incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an decrease in X chromosome nondisjunction." ;
rdfs:subClassOf obo:WBPhenotype_0001664 .
obo:GO_1903747 a rdfs:Class ;
rdfs:label "regulation of protein localization to mitochondrion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to mitochondrion." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_0070125 a rdfs:Class ;
rdfs:label "mitochondrial translational elongation" ;
rdfs:comment "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion." ;
rdfs:subClassOf obo:GO_0006414 .
obo:WBPhenotype_0001197 a rdfs:Class ;
rdfs:label "somatic gonad physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic gonad to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000613 .
obo:PATO_0001710 a rdfs:Class ;
rdfs:label "3-D extent" ;
rdfs:comment "A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions." ;
rdfs:subClassOf obo:PATO_0000117 .
obo:GO_0035177 a rdfs:Class ;
rdfs:label "larval foraging behavior" ;
rdfs:comment "The movement of a larva through a feeding substrate whilst feeding on food." ;
rdfs:subClassOf obo:GO_0030537 , obo:GO_0060756 .
obo:CHEBI_4792 a rdfs:Class ;
rdfs:label "enflurane" ;
rdfs:comment "An ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25698 , obo:CHEBI_36683 , obo:CHEBI_37143 .
obo:WBPhenotype_0001512 a rdfs:Class ;
rdfs:label "loss of left right asymmetry" ;
rdfs:comment "Bilaterally symmetric cell fail to acquire specific left-right asymmetric properties such as L/R specific cell position, cell death or gene expression." ;
rdfs:subClassOf obo:WBPhenotype_0000216 .
obo:WBPhenotype_0000496 a rdfs:Class ;
rdfs:label "male postdeirid sensilla absent" ;
rdfs:comment "Males lack the specialized sensory papillae that lie along the posterior half of the body." ;
rdfs:subClassOf obo:WBPhenotype_0001008 .
obo:WBPhenotype_0001432 a rdfs:Class ;
rdfs:label "over retracted male tail" ;
rdfs:comment "Adult males exhibit a truncated tail, often without a fan or have well-developed fans but squarish, truncated back ends compared to control. In C. elegans this is due to precocious male tail tip retraction beginning in the early L3 stage (normally retraction begins in the L4 stage). Condition can be lethal if the function of the anus is affected." ;
rdfs:subClassOf obo:WBPhenotype_0000070 , obo:WBPhenotype_0001297 .
obo:CHEBI_29222 a rdfs:Class ;
rdfs:label "hypochlorite" ;
rdfs:subClassOf obo:CHEBI_33437 , obo:CHEBI_37750 , obo:CHEBI_79389 .
obo:GO_0007568 a rdfs:Class ;
rdfs:label "obsolete aging" ;
rdfs:comment "OBSOLETE. A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700)." .
obo:PATO_0000487 a rdfs:Class ;
rdfs:label "responsive to" ;
rdfs:comment "A response quality inhering in a bearer by virtue of the bearer's disposition to react to a stimulus or an agent." ;
rdfs:subClassOf obo:PATO_0000077 .
obo:WBPhenotype_0000522 a rdfs:Class ;
rdfs:label "organism region behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of a certain defined body area of an animal in response to external or internal stimuli compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:CHEBI_18375 a rdfs:Class ;
rdfs:label "nucleoside 3',5'-cyclic phosphate" ;
rdfs:comment "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-3 and C-5 of the ribose ring are engaged in formation of a cyclic mono-, di-, tri- or tetra-phosphate." ;
rdfs:subClassOf obo:CHEBI_23447 .
obo:WBPhenotype_0000455 a rdfs:Class ;
rdfs:label "jerky movement" ;
rdfs:comment "Animals exhibit abrupt transitions while traveling from one location to another." ;
rdfs:subClassOf obo:WBPhenotype_0001701 .
obo:WBPhenotype_0000083 a rdfs:Class ;
rdfs:label "L3 arrest" ;
rdfs:comment "The developmental program of the animals does not continue past the third larval stage (L3)." ;
rdfs:subClassOf obo:WBPhenotype_0000056 , obo:WBPhenotype_0000753 , obo:WBPhenotype_0001019 .
obo:CHEBI_36961 a rdfs:Class ;
rdfs:label "chalcocarbonic acid" ;
rdfs:subClassOf obo:CHEBI_36962 .
obo:GO_0045936 a rdfs:Class ;
rdfs:label "negative regulation of phosphate metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ;
rdfs:subClassOf obo:GO_0010563 , obo:GO_0065007 .
obo:WBPhenotype_0000511 a rdfs:Class ;
rdfs:label "nuclear positioning variant" ;
rdfs:comment "Variations in the directed movement of the nucleus to a specific location within a cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0001344 .
obo:WBPhenotype_0002497 a rdfs:Class ;
rdfs:label "ectopic pharyngeal muscle"@en ;
rdfs:comment "Animals exhibit one or more pharyngeal muscle cells in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0002493 .
obo:WBbt_0000101 a rdfs:Class ;
rdfs:label "Lineage" ;
rdfs:comment "pedigree of nuclei, lineal descent from P0, the founder." ;
rdfs:subClassOf obo:WBbt_0000100 .
obo:CHEBI_48354 a rdfs:Class ;
rdfs:label "polar solvent" ;
rdfs:comment "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." ;
rdfs:subClassOf obo:CHEBI_46787 .
obo:GO_0006898 a rdfs:Class ;
rdfs:label "receptor-mediated endocytosis" ;
rdfs:comment "An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles." ;
rdfs:subClassOf obo:GO_0006897 .
obo:WBPhenotype_0000403 a rdfs:Class ;
rdfs:label "sperm transfer initiation defective" ;
rdfs:comment "Any defect in the movement of sperm out of the seminal vesicle and into the vas deferens following tonic insertion of spicules into the mating partner compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000284 .
obo:WBPhenotype_0000326 a rdfs:Class ;
rdfs:label "arecoline resistant" ;
rdfs:comment "Animals fail to respond to the concentration of arecoline that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001578 .
obo:GO_0046546 a rdfs:Class ;
rdfs:label "development of primary male sexual characteristics" ;
rdfs:comment "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion." ;
rdfs:subClassOf obo:GO_0045137 .
obo:GO_0040013 a rdfs:Class ;
rdfs:label "negative regulation of locomotion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." ;
rdfs:subClassOf obo:GO_0040012 , obo:GO_0048519 , obo:GO_0065007 .
obo:GO_0040022 a rdfs:Class ;
rdfs:label "feminization of hermaphroditic germ-line" ;
rdfs:comment "The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite." ;
rdfs:subClassOf obo:GO_0040021 .
obo:WBPhenotype_0001505 a rdfs:Class ;
rdfs:label "spontaneous reversal variant" ;
rdfs:comment "Any variation in the processes that govern spontaneous backward locomotion compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002320 .
obo:GO_0016043 a rdfs:Class ;
rdfs:label "cellular component organization" ;
rdfs:comment "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." ;
rdfs:subClassOf obo:GO_0071840 .
obo:WBPhenotype_0001909 a rdfs:Class ;
rdfs:label "obsolete translational repression variant" ;
rdfs:comment "OBSOLETE. Any variation in the prevention of mRNA translation that normally occurs in certain cells, compared to control." .
obo:CHEBI_50007 a rdfs:Class ;
rdfs:label "antimony coordination entity" ;
rdfs:subClassOf obo:CHEBI_36919 .
obo:GO_1905880 a rdfs:Class ;
rdfs:label "negative regulation of oogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1905879 , obo:GO_2000242 .
obo:WBPhenotype_0000611 a rdfs:Class ;
rdfs:label "muscle system physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000575 .
obo:PATO_0001552 a rdfs:Class ;
rdfs:label "decreased sensitivity of a process" ;
rdfs:comment "A sensitivity of a process which is lower than normal or average." ;
rdfs:subClassOf obo:PATO_0001457 , obo:PATO_0002302 .
obo:GO_1902884 a rdfs:Class ;
rdfs:label "positive regulation of response to oxidative stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of response to oxidative stress." ;
rdfs:subClassOf obo:GO_0048584 , obo:GO_0065007 , obo:GO_1902882 .
obo:WBPhenotype_0001028 a rdfs:Class ;
rdfs:label "nuclear appearance variant" ;
rdfs:comment "The morphological appearance of nuclei differs from control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002089 .
obo:WBPhenotype_0002458 a rdfs:Class ;
rdfs:label "maternal effect morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of any part of an animal caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis." ;
rdfs:subClassOf obo:WBPhenotype_0000535 .
obo:WBPhenotype_0002539 a rdfs:Class ;
rdfs:label "antimicrobial gene expression increased"@en ;
rdfs:comment "Animals exhibit an increase in the expression of one or more known, endogenous, antimicrobial genes, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002534 .
obo:WBPhenotype_0000207 a rdfs:Class ;
rdfs:label "defecation cycle variant" ;
rdfs:comment "Any variation in the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control ." ;
rdfs:subClassOf obo:WBPhenotype_0000650 .
obo:CHEBI_48218 a rdfs:Class ;
rdfs:label "antiseptic drug" ;
rdfs:comment "A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body)." ;
rdfs:subClassOf obo:CHEBI_35441 .
obo:GO_0060632 a rdfs:Class ;
rdfs:label "regulation of microtubule-based movement" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0032886 , obo:GO_0065007 .
obo:WBPhenotype_0001945 a rdfs:Class ;
rdfs:label "oocytes small" ;
rdfs:comment "The size of haploid female germ cells (oocytes) are significantly smaller compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001260 .
obo:WBPhenotype_0002176 a rdfs:Class ;
rdfs:label "seam cell morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure, organization or placement of the population of the lateral, alae-producing epithelial cells (seam cells), compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000899 .
obo:WBbt_0005107 a rdfs:Class ;
rdfs:label "labial sensillum" ;
rdfs:comment "sensillum of inner or outer labial." ;
rdfs:subClassOf obo:WBbt_0006929 .
obo:CHEBI_38314 a rdfs:Class ;
rdfs:label "pyrazines" ;
rdfs:subClassOf obo:CHEBI_38313 .
obo:WBPhenotype_0002391 a rdfs:Class ;
rdfs:label "cytokinesis failure" ;
rdfs:comment "Cells attempt to divide but fail to form two daughter cells." ;
rdfs:subClassOf obo:WBPhenotype_0002408 .
obo:WBPhenotype_0002405 a rdfs:Class ;
rdfs:label "pheromone behavioral response variant" ;
rdfs:comment "Animals exhibit variations in the behavioral response to pheromones, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001049 .
obo:WBPhenotype_0000470 a rdfs:Class ;
rdfs:label "HSN migration variant" ;
rdfs:comment "Any variation in the normal anterior movement of the HSN motor neurons from their birthplace in the tail to positions near the middle of the embryo compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001229 .
obo:GO_0071981 a rdfs:Class ;
rdfs:label "exit from diapause" ;
rdfs:comment "The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." ;
rdfs:subClassOf obo:GO_0022611 .
obo:CHEBI_33299 a rdfs:Class ;
rdfs:label "alkaline earth molecular entity" ;
rdfs:comment "An alkaline earth molecular entity is a molecular entity containing one or more atoms of an alkaline earth metal." ;
rdfs:subClassOf obo:CHEBI_33674 .
obo:GO_0060236 a rdfs:Class ;
rdfs:label "regulation of mitotic spindle organization" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090224 .
obo:WBPhenotype_0000388 a rdfs:Class ;
rdfs:label "sperm morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the mature male gamete, which merges with an oocyte to create a fertilized embryo copared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000900 .
obo:CHEBI_35845 a rdfs:Class ;
rdfs:label "gout suppressant" ;
rdfs:comment "A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout." ;
rdfs:subClassOf obo:CHEBI_35842 .
obo:GO_0061024 a rdfs:Class ;
rdfs:label "membrane organization" ;
rdfs:comment "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." ;
rdfs:subClassOf obo:GO_0016043 .
obo:WBbt_0006850 a rdfs:Class ;
rdfs:label "excretory secretory system" ;
rdfs:comment "An organ system consists of the excretory system and associated glands." ;
rdfs:subClassOf obo:WBbt_0005746 .
obo:WBPhenotype_0000340 a rdfs:Class ;
rdfs:label "imipramine resistant" ;
rdfs:comment "Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 , obo:WBPhenotype_0001598 .
obo:GO_0042995 a rdfs:Class ;
rdfs:label "cell projection" ;
rdfs:comment "A prolongation or process extending from a cell, e.g. a flagellum or axon." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0016358 a rdfs:Class ;
rdfs:label "dendrite development" ;
rdfs:comment "The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0031175 , obo:GO_0048856 .
obo:GO_0000075 a rdfs:Class ;
rdfs:label "cell cycle checkpoint signaling" ;
rdfs:comment "A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction." ;
rdfs:subClassOf obo:GO_0035556 , obo:GO_1901988 .
obo:PATO_0000513 a rdfs:Class ;
rdfs:label "insensitive toward" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's lacking sensitivity toward an external stimulus." ;
rdfs:subClassOf obo:PATO_0000085 .
obo:GO_0016755 a rdfs:Class ;
rdfs:label "aminoacyltransferase activity" ;
rdfs:comment "Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor)." ;
rdfs:subClassOf obo:GO_0016746 .
obo:WBPhenotype_0001063 a rdfs:Class ;
rdfs:label "egg laying phases variant" ;
rdfs:comment "Fluctuation pattern between inactive, active, and egg-laying states is atypical, based on the analysis of the distribution of the log intervals of egg-laying events compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000272 .
obo:WBPhenotype_0002389 a rdfs:Class ;
rdfs:label "anaphase variant" ;
rdfs:comment "Any variation in the stage of meiotic or mitotic cell division in which the chromosomes move away from one another to opposite poles of the spindle." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:CHEBI_48279 a rdfs:Class ;
rdfs:label "serotonergic antagonist" ;
rdfs:comment "Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists." ;
rdfs:subClassOf obo:CHEBI_48278 .
obo:WBPhenotype_0000005 a rdfs:Class ;
rdfs:label "hyperactive egg laying" ;
rdfs:comment "Eggs are laid at an earlier stage of development, eggs are laid in the presence of inhibitors of egg laying, or the inactive phase of the egg-laying cycle is significantly shorter when compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000640 .
obo:PATO_0000279 a rdfs:Class ;
rdfs:label "male fertility" ;
rdfs:comment "A fertility quality of inhering in a male by virtue of the bearer's disposition to initiate, sustain, or support reproduction." ;
rdfs:subClassOf obo:PATO_0000274 .
obo:WBPhenotype_0001443 a rdfs:Class ;
rdfs:label "aqueous chemosensory response variant" ;
rdfs:comment "Animals exhibit variations in response to water-soluble chemicals, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001040 .
obo:WBPhenotype_0000463 a rdfs:Class ;
rdfs:label "metabolic pathway variant" ;
rdfs:comment "Animals exhibit variations in processes that are responsible for chemical changes compared to control animals. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0000124 a rdfs:Class ;
rdfs:label "enzyme activity reduced" ;
rdfs:comment "Any variation that results in a decrease in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ;
rdfs:subClassOf obo:WBPhenotype_0000727 .
obo:WBPhenotype_0002411 a rdfs:Class ;
rdfs:label "cleavage furrow initiation defective" ;
rdfs:comment "Cells exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ;
rdfs:subClassOf obo:WBPhenotype_0002410 .
obo:WBPhenotype_0000533 a rdfs:Class ;
rdfs:label "cell morphology variant" ;
rdfs:comment "Any variation in the form or composition of the basic structural and functional unit of all organisms compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
rdfs:subClassOf obo:WBPhenotype_0000520 , obo:WBPhenotype_0002552 .
obo:GO_0044771 a rdfs:Class ;
rdfs:label "meiotic cell cycle phase transition" ;
rdfs:comment "The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase." ;
rdfs:subClassOf obo:GO_0044770 , obo:GO_1903046 .
obo:GO_0070131 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial translation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ;
rdfs:subClassOf obo:GO_0045727 , obo:GO_0065007 , obo:GO_0070129 .
obo:WBPhenotype_0000218 a rdfs:Class ;
rdfs:label "vulval cell induction increased" ;
rdfs:comment "An excess number of vulval precursor cells receive an inductive signal leading to an increased number of VPCs adopting vulval fates compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001272 .
obo:GO_0007413 a rdfs:Class ;
rdfs:label "axonal fasciculation" ;
rdfs:comment "The collection of axons into a bundle of rods, known as a fascicle." ;
rdfs:subClassOf obo:GO_0008038 , obo:GO_0106030 .
obo:GO_0060457 a rdfs:Class ;
rdfs:label "negative regulation of digestive system process" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0044058 , obo:GO_0051241 , obo:GO_0065007 .
obo:WBPhenotype_0001572 a rdfs:Class ;
rdfs:label "masculinized" ;
rdfs:comment "Animals that are not ordinarily male, exhibit male-specific attributes. In C. elegans, XX animals exhibit male-specific attributes." ;
rdfs:subClassOf obo:WBPhenotype_0001022 .
obo:WBls_0000805 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during elongating embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the elongating embryo life stage" ;
rdfs:subClassOf obo:WBls_0000803 .
obo:CHEBI_38515 a rdfs:Class ;
rdfs:label "isoquinoline alkaloid fundamental parent" ;
rdfs:subClassOf obo:CHEBI_35506 .
obo:WBPhenotype_0001551 a rdfs:Class ;
rdfs:label "dauer cuticle variant" ;
rdfs:comment "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) during the dauer larva stage, compared to control animals (Wormatlas). The dauer larval stage is a developmentally arrested larval stage that is specialized for survival under harsh, or otherwise unfavorable environmental conditions." ;
rdfs:subClassOf obo:WBPhenotype_0000948 , obo:WBPhenotype_0001545 .
obo:GO_0008156 a rdfs:Class ;
rdfs:label "negative regulation of DNA replication" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication." ;
rdfs:subClassOf obo:GO_0006275 , obo:GO_0051053 , obo:GO_0065007 .
obo:WBPhenotype_0000994 a rdfs:Class ;
rdfs:label "intestinal contractions variant" ;
rdfs:comment "Any variations in the contraction of the enteric muscles that are involved in defecation motor program compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000210 .
obo:WBPhenotype_0000414 a rdfs:Class ;
rdfs:label "cell fate transformation" ;
rdfs:comment "The cell takes on a different identity from which it was initially committed." ;
rdfs:subClassOf obo:WBPhenotype_0000216 .
obo:WBPhenotype_0001009 a rdfs:Class ;
rdfs:label "developmental pigmentation variant" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular developmental stage of the amimal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000519 , obo:WBPhenotype_0000527 .
obo:GO_0140013 a rdfs:Class ;
rdfs:label "meiotic nuclear division" ;
rdfs:comment "One of the two nuclear divisions that occur as part of the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0000280 , obo:GO_1903046 .
obo:WBPhenotype_0001598 a rdfs:Class ;
rdfs:label "inhibitor of serotonin uptake variant" ;
rdfs:comment "Treatment with inhibitors of serotonin reuptake does not elicit the same response as observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0000500 a rdfs:Class ;
rdfs:label "acetylcholinesterase inhibitor hypersensitive" ;
rdfs:comment "Animals respond to an acetylcholinesterase inhibitor at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001290 .
obo:CHEBI_61296 a rdfs:Class ;
rdfs:label "adenyl ribonucleotide" ;
rdfs:comment "A purine riboncleotide where adenine is the purine." ;
rdfs:subClassOf obo:CHEBI_26400 , obo:CHEBI_61293 .
obo:GO_0070201 a rdfs:Class ;
rdfs:label "regulation of establishment of protein localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_0032888 a rdfs:Class ;
rdfs:label "regulation of mitotic spindle elongation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle." ;
rdfs:subClassOf obo:GO_0032887 , obo:GO_0065007 .
obo:WBPhenotype_0000337 a rdfs:Class ;
rdfs:label "grinder relaxation defective" ;
rdfs:comment "Failure of the grinder to come to a full relaxed position between pumps compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001480 .
obo:WBPhenotype_0002566 a rdfs:Class ;
rdfs:label "long-term associative olfactory memory phenotype"@en ;
rdfs:comment "Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s)." ;
rdfs:subClassOf obo:WBPhenotype_0002565 , obo:WBPhenotype_0002568 .
obo:WBPhenotype_0000092 a rdfs:Class ;
rdfs:label "intestinal cell proliferation variant" ;
rdfs:comment "Any variation in the processes that govern the expansion of intestinal cell populations compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000171 , obo:WBPhenotype_0000536 , obo:WBPhenotype_0000705 , obo:WBPhenotype_0001093 .
obo:WBPhenotype_0002342 a rdfs:Class ;
rdfs:label "bent posture increased" ;
rdfs:comment "Animals exhibit increased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends." ;
rdfs:subClassOf obo:WBPhenotype_0002341 .
obo:WBPhenotype_0000641 a rdfs:Class ;
rdfs:label "activity level variant" ;
rdfs:comment "Any variation in the degree of movement compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000643 .
obo:WBPhenotype_0001934 a rdfs:Class ;
rdfs:label "vulval muscle extension variant" ;
rdfs:comment "Any variation in the extension of vulval muscles compared to control. In C. elegans contralateral vulval muscles fail to meet at the midline." ;
rdfs:subClassOf obo:WBPhenotype_0001314 .
obo:PATO_0000085 a rdfs:Class ;
rdfs:label "sensitivity toward" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's disposition to detect or perceive external stimulation." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:UBERON_0000061 a rdfs:Class ;
rdfs:label "anatomical structure" ;
rdfs:comment "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:WBPhenotype_0002132 a rdfs:Class ;
rdfs:label "protein complex organization variant" ;
rdfs:comment "The formation, organization, or stability of a protein complex is altered in comparison to corresponding complexes in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001370 .
obo:WBPhenotype_0002447 a rdfs:Class ;
rdfs:label "acute pumping response to light variant" ;
rdfs:comment "Animals exhibit variations in the acute pharyngeal pumping response to light, during which the pharyngeal pumping rate initially (0-5 seconds after light exposure onset) decreases in response to light, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002446 .
obo:WBPhenotype_0000902 a rdfs:Class ;
rdfs:label "intestinal cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of intestinal cells compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000710 , obo:WBPhenotype_0002108 .
obo:CHEBI_33675 a rdfs:Class ;
rdfs:label "p-block molecular entity" ;
rdfs:comment "A main group molecular entity that contains one or more atoms of a p-block element." ;
rdfs:subClassOf obo:CHEBI_33579 .
obo:WBPhenotype_0001873 a rdfs:Class ;
rdfs:label "meiotic spindle assembly defective" ;
rdfs:comment "Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the meiotic spindle, the array of microtubules and associated molecules that serves to move duplicated and/or homologous chromosomes apart." ;
rdfs:subClassOf obo:WBPhenotype_0001868 .
obo:GO_0098632 a rdfs:Class ;
rdfs:label "cell-cell adhesion mediator activity" ;
rdfs:comment "The binding by a cell-adhesion protein on the cell surface to an extracellular component of a different cell, to mediate adhesion of the cell to another cell." ;
rdfs:subClassOf obo:GO_0005515 , obo:GO_0098631 .
obo:CHEBI_58165 a rdfs:Class ;
rdfs:label "3',5'-cyclic AMP(1-)" ;
rdfs:comment "An organophosphate oxoanion that is the conjugate base of 3',5'-cyclic AMP arising from deprotonation of the free phosphate OH group; major species at pH 7.3." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_58945 .
obo:WBPhenotype_0000430 a rdfs:Class ;
rdfs:label "male copulatory structure development variant" ;
rdfs:comment "Any variation in the progression of the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm over time from its formation to its mature structure compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000429 .
obo:WBPhenotype_0000650 a rdfs:Class ;
rdfs:label "defecation variant" ;
rdfs:comment "Animals exhibit variations in the processes involved in eliminating gut contents compared to control animals. In C. elegans the sequence of events during defecation includes posterior body contraction (pBoc), relaxation, anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp), and intercycle period (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:WBPhenotype_0002433 a rdfs:Class ;
rdfs:label "EGF-induced sleep resistant" ;
rdfs:comment "Animals respond with sleeping behavior induced through the EGF pathway, more rigorously than control animals. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals." ;
rdfs:subClassOf obo:WBPhenotype_0001524 .
obo:WBPhenotype_0000897 a rdfs:Class ;
rdfs:label "connective tissue development variant" ;
rdfs:comment "Variations in the material made up of fibers forming a framework and support structure for body tissues and organs compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000200 .
obo:PATO_0000608 a rdfs:Class ;
rdfs:label "closed" ;
rdfs:comment "A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view." ;
rdfs:subClassOf obo:PATO_0000136 .
obo:PATO_0000461 a rdfs:Class ;
rdfs:label "normal" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." ;
rdfs:subClassOf obo:PATO_0000068 .
obo:GO_0060903 a rdfs:Class ;
rdfs:label "positive regulation of meiosis I" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ;
rdfs:subClassOf obo:GO_0045836 , obo:GO_0060631 , obo:GO_0065007 .
obo:GO_0033119 a rdfs:Class ;
rdfs:label "negative regulation of RNA splicing" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing." ;
rdfs:subClassOf obo:GO_0010629 , obo:GO_0043484 , obo:GO_0065007 .
obo:CHEBI_39281 a rdfs:Class ;
rdfs:label "fluoromethanes" ;
rdfs:comment "A halomethane that is methane in which one or more hydrogens has been replaced by fluorine." ;
rdfs:subClassOf obo:CHEBI_24067 , obo:CHEBI_39279 .
obo:WBPhenotype_0001974 a rdfs:Class ;
rdfs:label "germ cell compartment small" ;
rdfs:comment "Germ cell compartments are smaller than that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001973 .
obo:GO_0016301 a rdfs:Class ;
rdfs:label "kinase activity" ;
rdfs:comment "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ;
rdfs:subClassOf obo:GO_0003674 .
obo:PATO_0001564 a rdfs:Class ;
rdfs:label "extra or missing processual parts" ;
rdfs:comment "A quality of a process inhering in a bearer by virtue of the bearer's processual parts." ;
rdfs:subClassOf obo:PATO_0001236 .
obo:GO_0040034 a rdfs:Class ;
rdfs:label "regulation of development, heterochronic" ;
rdfs:comment "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." ;
rdfs:subClassOf obo:GO_0050793 .
obo:GO_0071824 a rdfs:Class ;
rdfs:label "protein-DNA complex organization" ;
rdfs:comment "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex." ;
rdfs:subClassOf obo:GO_0043933 .
obo:WBbt_0005022 a rdfs:Class ;
rdfs:label "Z1.paapp male" ;
rdfs:comment "Seminal vesicle, outer; cell of pedigree Z1.paapp in male." ;
rdfs:subClassOf obo:WBbt_0007030 , obo:WBbt_0008249 .
obo:WBPhenotype_0000709 a rdfs:Class ;
rdfs:label "pharyngeal morphology variant" ;
rdfs:comment "Variations in the form or composition of the mouthparts at the anterior end of the digestive tract which contain a series of radial muscles, related neurons and epithelial cells, and several gland cells which may aid in digestion compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000598 , obo:WBPhenotype_0002553 .
obo:GO_0042445 a rdfs:Class ;
rdfs:label "hormone metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0010817 .
obo:CHEBI_23357 a rdfs:Class ;
rdfs:label "cofactor" ;
rdfs:comment "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." ;
rdfs:subClassOf obo:CHEBI_52206 .
obo:GO_0009309 a rdfs:Class ;
rdfs:label "amine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0009308 .
obo:PATO_0002002 a rdfs:Class ;
rdfs:label "has extra parts of type" ;
rdfs:comment "The bearer of this quality has_part > n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part." ;
rdfs:subClassOf obo:PATO_0000470 , obo:PATO_0002083 , obo:PATO_0002305 .
obo:WBPhenotype_0000351 a rdfs:Class ;
rdfs:label "failure to hatch" ;
rdfs:comment "Animals fail to emerge from an egg shell." ;
rdfs:subClassOf obo:WBPhenotype_0000048 , obo:WBPhenotype_0000050 .
obo:GO_0045842 a rdfs:Class ;
rdfs:label "positive regulation of mitotic metaphase/anaphase transition" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ;
rdfs:subClassOf obo:GO_0030071 , obo:GO_0045840 , obo:GO_0065007 , obo:GO_1901970 , obo:GO_1901992 , obo:GO_1902101 .
obo:WBPhenotype_0001091 a rdfs:Class ;
rdfs:label "larval defecation variant" ;
rdfs:comment "Animals exhibit variations in the elimination of fecal matter during the larval stage compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000650 .
obo:GO_0030534 a rdfs:Class ;
rdfs:label "adult behavior" ;
rdfs:comment "Behavior in a fully developed and mature organism." ;
rdfs:subClassOf obo:GO_0007610 .
obo:WBPhenotype_0001424 a rdfs:Class ;
rdfs:label "oocyte physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the oocyte to carry out its normal functions or activities, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000929 , obo:WBPhenotype_0000987 .
obo:CHEBI_15356 a rdfs:Class ;
rdfs:label "cysteine" ;
rdfs:comment "A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3." ;
rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_26834 , obo:CHEBI_33704 .
obo:CHEBI_26523 a rdfs:Class ;
rdfs:label "reactive oxygen species" ;
rdfs:comment "Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." ;
rdfs:subClassOf obo:CHEBI_25806 .
obo:WBPhenotype_0001045 a rdfs:Class ;
rdfs:label "sporadic pumping" ;
rdfs:comment "Pharyngeal pumping contractions are brief and occur arhythmically in response to stimulus compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000019 .
obo:WBPhenotype_0000314 a rdfs:Class ;
rdfs:label "scrawny" ;
rdfs:comment "Animals are slight or meager in body size compared to control animals at the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0000231 .
obo:WBPhenotype_0001334 a rdfs:Class ;
rdfs:label "hermaphrodite sex muscle morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the muscles of the adult hermaphrodite reproductive system compared to control. In C. elegans hermaphrodites these muscles include the vulval and uterine muscles, located near the vulva in the midbody, which all derive from the M myoblast (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001335 .
obo:CHEBI_49870 a rdfs:Class ;
rdfs:label "antimonous acid" ;
rdfs:subClassOf obo:CHEBI_36920 .
obo:WBbt_0008426 a rdfs:Class ;
rdfs:label "nose" ;
rdfs:comment "The extreme anterior portion of the body." ;
rdfs:subClassOf obo:WBbt_0005738 .
obo:CHEBI_28976 a rdfs:Class ;
rdfs:label "carbonic acid" ;
rdfs:subClassOf obo:CHEBI_35605 , obo:CHEBI_36961 .
obo:GO_0032877 a rdfs:Class ;
rdfs:label "positive regulation of DNA endoreduplication" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of DNA endoreduplication." ;
rdfs:subClassOf obo:GO_0032875 , obo:GO_0065007 , obo:GO_0090068 , obo:GO_2000105 .
obo:GO_0030516 a rdfs:Class ;
rdfs:label "regulation of axon extension" ;
rdfs:comment "Any process that modulates the rate, direction or extent of axon extension." ;
rdfs:subClassOf obo:GO_0048638 , obo:GO_0061387 , obo:GO_0065007 .
obo:CHEBI_16375 a rdfs:Class ;
rdfs:label "D-cysteine" ;
rdfs:comment "An optically active form of cysteine having D-configuration." ;
rdfs:subClassOf obo:CHEBI_15356 , obo:CHEBI_16733 .
obo:GO_0006936 a rdfs:Class ;
rdfs:label "muscle contraction" ;
rdfs:comment "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." ;
rdfs:subClassOf obo:GO_0003012 .
obo:PATO_0001999 a rdfs:Class ;
rdfs:label "lacks parts or has fewer parts of type" ;
rdfs:comment "The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type." ;
rdfs:subClassOf obo:PATO_0002083 .
obo:CHEBI_26421 a rdfs:Class ;
rdfs:label "pyridines" ;
rdfs:comment "Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:WBPhenotype_0000429 a rdfs:Class ;
rdfs:label "copulatory structure development variant" ;
rdfs:comment "Any variation in the progression of the specialized structures of the animal which allow the successful transfer of sperm from one organism to another, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000624 .
obo:WBPhenotype_0004006 a rdfs:Class ;
rdfs:label "post hermaphrodite contact variant" ;
rdfs:comment "Males exhibit variations in mating behavior after contacting its mate compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000648 .
obo:WBPhenotype_0001523 a rdfs:Class ;
rdfs:label "extracellular matrix variant" ;
rdfs:comment "Any variation in the makeup, density or area of the ECM compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000912 , obo:WBPhenotype_0002089 .
obo:CHEBI_50339 a rdfs:Class ;
rdfs:label "4-aminobutyl group" ;
rdfs:subClassOf obo:CHEBI_50325 .
obo:GO_0032386 a rdfs:Class ;
rdfs:label "regulation of intracellular transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0060341 , obo:GO_0065007 .
obo:GO_0019222 a rdfs:Class ;
rdfs:label "regulation of metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0042074 a rdfs:Class ;
rdfs:label "cell migration involved in gastrulation" ;
rdfs:comment "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." ;
rdfs:subClassOf obo:GO_0001667 , obo:GO_0016477 .
obo:WBPhenotype_0000399 a rdfs:Class ;
rdfs:label "somatic gonad development variant" ;
rdfs:comment "Any variation in the progression of the components of the gonad that are separate from the germline proper over time from its formation to its mature structure compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000691 .
obo:GO_0023052 a rdfs:Class ;
rdfs:label "signaling" ;
rdfs:comment "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." ;
rdfs:subClassOf obo:GO_0050789 .
obo:WBPhenotype_0000394 a rdfs:Class ;
rdfs:label "electrophoretic variant protein" ;
rdfs:comment "Any variation in the movement of a protein through a gel matrix when an electric field is applied compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000112 .
obo:PATO_0001509 a rdfs:Class ;
rdfs:label "functionality" ;
rdfs:comment "A quality of a single physical entity that arises by virtue of whether the bearer exhibits the ability to perform a regular function(s)." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:GO_0007346 a rdfs:Class ;
rdfs:label "regulation of mitotic cell cycle" ;
rdfs:comment "Any process that modulates the rate or extent of progress through the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0051726 , obo:GO_0065007 .
obo:GO_0031349 a rdfs:Class ;
rdfs:label "positive regulation of defense response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a defense response." ;
rdfs:subClassOf obo:GO_0031347 , obo:GO_0048584 , obo:GO_0065007 .
obo:CHEBI_43451 a rdfs:Class ;
rdfs:label "hydrogen iodide" ;
rdfs:comment "A diatomic molecule containing covalently bonded hydrogen and iodine atoms." ;
rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18140 , obo:CHEBI_37176 .
obo:GO_0009415 a rdfs:Class ;
rdfs:label "response to water" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water." ;
rdfs:subClassOf obo:GO_0001101 , obo:GO_0009628 , obo:GO_1901700 .
obo:CHEBI_35295 a rdfs:Class ;
rdfs:label "homopolycyclic compound" ;
rdfs:subClassOf obo:CHEBI_33597 , obo:CHEBI_33635 .
obo:GO_0048540 a rdfs:Class ;
rdfs:label "bursa of Fabricius development" ;
rdfs:comment "The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation." ;
rdfs:subClassOf obo:GO_0048534 .
obo:PATO_0002305 a rdfs:Class ;
rdfs:label "increased object quality" ;
rdfs:comment "A quality of an object that has a value that is increased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0001241 , obo:PATO_0002300 .
obo:WBPhenotype_0000061 a rdfs:Class ;
rdfs:label "extended life span" ;
rdfs:comment "The duration of viability in the adult phase of the life-cycle surpasses that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000039 .
obo:WBPhenotype_0002637 a rdfs:Class ;
rdfs:label "iron levels decreased"@en ;
rdfs:comment "Animals (or cells of the animal) exhibit reduced levels of iron in the body (or cells) compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002046 .
obo:WBPhenotype_0001085 a rdfs:Class ;
rdfs:label "butanone chemotaxis defective" ;
rdfs:comment "Failure to execute characteristic response to butanone compared to control. In C. elegans, animals move towards typically attractive concentrations of butanone." ;
rdfs:subClassOf obo:WBPhenotype_0001438 , obo:WBPhenotype_0001469 .
obo:CHEBI_23924 a rdfs:Class ;
rdfs:label "enzyme inhibitor" ;
rdfs:comment "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." ;
rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 .
obo:WBPhenotype_0002479 a rdfs:Class ;
rdfs:label "axon regeneration enhanced" ;
rdfs:comment "Any increase in regenerative regrowth of axons compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000880 .
obo:WBPhenotype_0001642 a rdfs:Class ;
rdfs:label "cell cleavage variant emb" ;
rdfs:comment "Variations that disrupt stereotypical embryonic cleavage patterns (such as cleavage rate, division axes or asymmetric division)." ;
rdfs:subClassOf obo:WBPhenotype_0000266 .
obo:WBPhenotype_0001367 a rdfs:Class ;
rdfs:label "proctodeum development variant" ;
rdfs:comment "Any variation in the process whose specific outcome is the progression of the male proctodeum over time, from its formation to the mature structure, compared to control. The union of the vas deferens and the intestine give rise to the proctodeum which contains copulatory spicules." ;
rdfs:subClassOf obo:WBPhenotype_0000347 , obo:WBPhenotype_0000930 , obo:WBPhenotype_0001297 .
obo:CHEBI_35573 a rdfs:Class ;
rdfs:label "organic mancude parent" ;
rdfs:subClassOf obo:CHEBI_33245 , obo:CHEBI_35568 .
obo:CHEBI_23003 a rdfs:Class ;
rdfs:label "carbamate ester" ;
rdfs:comment "Any ester of carbamic acid or its N-substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_33308 .
obo:PATO_0000912 a rdfs:Class ;
rdfs:label "increased rate" ;
rdfs:comment "A rate which is relatively high." ;
rdfs:subClassOf obo:PATO_0000161 , obo:PATO_0002304 .
obo:CHEBI_52217 a rdfs:Class ;
rdfs:label "pharmaceutical" ;
rdfs:comment "Any substance introduced into a living organism with therapeutic or diagnostic purpose." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_0031338 a rdfs:Class ;
rdfs:label "regulation of vesicle fusion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vesicle fusion." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0060627 , obo:GO_0065007 .
obo:GO_0023051 a rdfs:Class ;
rdfs:label "regulation of signaling" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a signaling process." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:GO_0060456 a rdfs:Class ;
rdfs:label "positive regulation of digestive system process" ;
rdfs:comment "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0044058 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0008089 a rdfs:Class ;
rdfs:label "anterograde axonal transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons." ;
rdfs:subClassOf obo:GO_0098930 .
obo:GO_0032060 a rdfs:Class ;
rdfs:label "bleb assembly" ;
rdfs:comment "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." ;
rdfs:subClassOf obo:GO_0120031 .
obo:WBPhenotype_0002653 a rdfs:Class ;
rdfs:label "exopher production decreased"@en ;
rdfs:comment "Cells exhibit a decrease in production of exophers compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002651 .
obo:WBPhenotype_0000250 a rdfs:Class ;
rdfs:label "octopamine metabolism variant" ;
rdfs:comment "Animals exhibit variations in any chemical reaction or pathway involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000221 , obo:WBPhenotype_0001518 .
obo:WBPhenotype_0002165 a rdfs:Class ;
rdfs:label "muscle excitability variant" ;
rdfs:comment "The extent or other quality of the excitatory postsynaptic potential (EPSP) induced by in vitro stimuli differs from that of controls." ;
rdfs:subClassOf obo:WBPhenotype_0001735 , obo:WBPhenotype_0002014 .
obo:GO_0072687 a rdfs:Class ;
rdfs:label "meiotic spindle" ;
rdfs:comment "A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle." ;
rdfs:subClassOf obo:GO_0005819 .
obo:CHEBI_23905 a rdfs:Class ;
rdfs:label "monoatomic anion" ;
rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_24867 .
obo:GO_1903146 a rdfs:Class ;
rdfs:label "regulation of autophagy of mitochondrion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process." ;
rdfs:subClassOf obo:GO_0010506 , obo:GO_0065007 .
obo:WBPhenotype_0001413 a rdfs:Class ;
rdfs:label "bacterially unswollen" ;
rdfs:comment "Animals do not exhibit tail-swelling in response to infection by a bacterial pathogen (such as Microbacterium nematophilum) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000073 , obo:WBPhenotype_0001014 , obo:WBPhenotype_0002545 .
obo:PATO_0000375 a rdfs:Class ;
rdfs:label "decreased distance" ;
rdfs:comment "A distance which is lesser relative to the normal or average." ;
rdfs:subClassOf obo:PATO_0000040 , obo:PATO_0002303 .
obo:PATO_0000161 a rdfs:Class ;
rdfs:label "rate" ;
rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time." ;
rdfs:subClassOf obo:PATO_0002062 .
obo:WBPhenotype_0002486 a rdfs:Class ;
rdfs:label "persistent primordial germ cell lobes"@en ;
rdfs:comment "Animals exhibit persistent cellular lobes of the primordial germ cells Z2 and/or Z3 at the L1 larval stage or later, in contrast to wild type animals" ;
rdfs:subClassOf obo:WBPhenotype_0002485 .
obo:GO_0070925 a rdfs:Class ;
rdfs:label "organelle assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0022607 .
obo:CHEBI_76507 a rdfs:Class ;
rdfs:label "marine metabolite" ;
rdfs:comment "Any metabolite produced during a metabolic reaction in marine macro- and microorganisms." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:GO_0050686 a rdfs:Class ;
rdfs:label "negative regulation of mRNA processing" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing." ;
rdfs:subClassOf obo:GO_0050684 , obo:GO_0065007 , obo:GO_1903312 .
obo:WBPhenotype_0001663 a rdfs:Class ;
rdfs:label "organism oxidative stress resistant" ;
rdfs:comment "Animals fail to respond to the levels of reactive oxygen species that elicit a response in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001620 .
obo:GO_0051148 a rdfs:Class ;
rdfs:label "negative regulation of muscle cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0051147 , obo:GO_0065007 .
obo:GO_0001933 a rdfs:Class ;
rdfs:label "negative regulation of protein phosphorylation" ;
rdfs:comment "Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein." ;
rdfs:subClassOf obo:GO_0001932 , obo:GO_0031400 , obo:GO_0042326 , obo:GO_0065007 .
obo:CHEBI_33286 a rdfs:Class ;
rdfs:label "agrochemical" ;
rdfs:comment "An agrochemical is a substance that is used in agriculture or horticulture." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:WBbt_0005763 a rdfs:Class ;
rdfs:label "Functional system" ;
rdfs:comment "concerns with functional aspects of cells and anatomical parts" ;
rdfs:subClassOf obo:WBbt_0000100 .
obo:WBls_0000027 a rdfs:Class ;
rdfs:label "L2 larva Ce" ;
rdfs:comment "The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch." ;
rdfs:subClassOf obo:WBls_0000107 , obo:WBls_0000819 .
obo:GO_0050924 a rdfs:Class ;
rdfs:label "positive regulation of negative chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." ;
rdfs:subClassOf obo:GO_0050921 , obo:GO_0050923 , obo:GO_0065007 .
obo:WBbt_0005116 a rdfs:Class ;
rdfs:label "inner labial sensillum" ;
rdfs:comment "sensory organ of the inner labial." ;
rdfs:subClassOf obo:WBbt_0005107 .
obo:WBPhenotype_0002396 a rdfs:Class ;
rdfs:label "tumor prolapse frequency decreased" ;
rdfs:comment "Animals with a tumorous germline exhibit a decreased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000038 .
obo:CHEBI_25106 a rdfs:Class ;
rdfs:label "macrolide" ;
rdfs:comment "A macrocyclic lactone with a ring of twelve or more members derived from a polyketide." ;
rdfs:subClassOf obo:CHEBI_26188 , obo:CHEBI_63944 .
obo:GO_1901890 a rdfs:Class ;
rdfs:label "positive regulation of cell junction assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell junction assembly." ;
rdfs:subClassOf obo:GO_0044089 , obo:GO_0051130 , obo:GO_0065007 , obo:GO_1901888 .
obo:WBPhenotype_0002308 a rdfs:Class ;
rdfs:label "pausing variant" ;
rdfs:comment "Animals exhibit variations in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001213 .
obo:WBPhenotype_0001714 a rdfs:Class ;
rdfs:label "pirouette variant" ;
rdfs:comment "Animals exhibit variations in turning bouts, consisting of one or more sharp turning events separating consecutive runs, which serve to orient the animal within a gradient, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002311 .
obo:CHEBI_35584 a rdfs:Class ;
rdfs:label "purine" ;
rdfs:comment "A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_26401 , obo:CHEBI_35570 .
obo:WBPhenotype_0002656 a rdfs:Class ;
rdfs:label "exopher production in muscle increased"@en ;
rdfs:comment "Muscle cells exhibit an increase in production of exophers compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002652 , obo:WBPhenotype_0002654 .
obo:GO_0005856 a rdfs:Class ;
rdfs:label "cytoskeleton" ;
rdfs:comment "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." ;
rdfs:subClassOf obo:GO_0043232 .
obo:WBPhenotype_0000243 a rdfs:Class ;
rdfs:label "engulfment failure by killer cell" ;
rdfs:comment "Removal of cell corpses through a dedicated engulfment pathway is defective." ;
rdfs:subClassOf obo:WBPhenotype_0000885 .
obo:WBPhenotype_0001923 a rdfs:Class ;
rdfs:label "fewer seam cells" ;
rdfs:comment "The population of the lateral, alae-producing epithelial cells (seam cells) is reduced compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002174 , obo:WBPhenotype_0002569 .
obo:GO_0009712 a rdfs:Class ;
rdfs:label "catechol-containing compound metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." ;
rdfs:subClassOf obo:GO_0018958 .
obo:GO_1902373 a rdfs:Class ;
rdfs:label "negative regulation of mRNA catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process." ;
rdfs:subClassOf obo:GO_0010628 , obo:GO_0061013 , obo:GO_0065007 , obo:GO_1902369 , obo:GO_1903312 .
obo:WBPhenotype_0002525 a rdfs:Class ;
rdfs:label "diet response variant"@en ;
rdfs:comment "Animals exhibit variations in their response to diet, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:PATO_0001492 a rdfs:Class ;
rdfs:label "growth rate" ;
rdfs:comment "The rate or speed of the change in size of an individual entity or change in number of a population." ;
rdfs:subClassOf obo:PATO_0000161 .
obo:WBPhenotype_0001747 a rdfs:Class ;
rdfs:label "zinc response variant" ;
rdfs:comment "Animals exhibit variations in the change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000591 .
obo:CHEBI_24835 a rdfs:Class ;
rdfs:label "inorganic molecular entity" ;
rdfs:comment "A molecular entity that contains no carbon." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:WBbt_0005812 a rdfs:Class ;
rdfs:label "excretory cell" ;
rdfs:comment "H-shaped cell associated with the excretory system, largest cell in C. elegans." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:CHEBI_18133 a rdfs:Class ;
rdfs:label "hexose" ;
rdfs:comment "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." ;
rdfs:subClassOf obo:CHEBI_35381 .
obo:WBPhenotype_0001833 a rdfs:Class ;
rdfs:label "membrane trafficking variant" ;
rdfs:comment "Any variation in the directed movement of substances in a cell, from one side of a membrane to another, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0001804 a rdfs:Class ;
rdfs:label "fat associated bodies reduced" ;
rdfs:comment "Animals exhibit a decrease in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by decreases in the number of Nile Red or BODIPY 493/503 staining bodies." ;
rdfs:subClassOf obo:WBPhenotype_0001901 .
obo:WBbt_0006760 a rdfs:Class ;
rdfs:label "uterus" ;
rdfs:comment "The organ in which the eggs are developed and protected until laid." ;
rdfs:subClassOf obo:WBbt_0005729 .
obo:WBPhenotype_0000296 a rdfs:Class ;
rdfs:label "spicules crumpled" ;
rdfs:comment "The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) are deformed. In C. elegans males there are two copulatory spicules." ;
rdfs:subClassOf obo:WBPhenotype_0000443 .
obo:WBPhenotype_0000601 a rdfs:Class ;
rdfs:label "excretory secretory system morphology variant" ;
rdfs:comment "Variations in the form, structure or composition of related tissues that allow the animal to secrete saline fluid and maintain a proper salt balance compared to control. In C. elegans, four cell types (1 pore cell, 1 duct cell, 1 canal cell and a fused pair of gland cells) make up the excretory system (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000534 .
obo:CHEBI_16555 a rdfs:Class ;
rdfs:label "ethanethioic S-acid" ;
rdfs:comment "A thioacetic acid that is acetic acid in which the oxygen atom of the hydroxy group has been replaced by a sulfur atom." ;
rdfs:subClassOf obo:CHEBI_26952 .
obo:WBPhenotype_0001547 a rdfs:Class ;
rdfs:label "dauer metabolism phenotype" ;
rdfs:comment "Animals exhibit variations in the chemical reactions and pathways that occur during the dauer life stage, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002527 .
obo:CHEBI_50910 a rdfs:Class ;
rdfs:label "neurotoxin" ;
rdfs:comment "A poison that interferes with the functions of the nervous system." ;
rdfs:subClassOf obo:CHEBI_52209 , obo:CHEBI_64909 .
obo:GO_0030334 a rdfs:Class ;
rdfs:label "regulation of cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000145 .
obo:GO_1905627 a rdfs:Class ;
rdfs:label "regulation of serotonin biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0065007 .
obo:WBPhenotype_0001518 a rdfs:Class ;
rdfs:label "biogenic amine physiology variant" ;
rdfs:comment "Any variation in the levels and/or localization of biogenic amines compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:WBPhenotype_0001017 a rdfs:Class ;
rdfs:label "adult growth variant" ;
rdfs:comment "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the adult stage compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001015 .
obo:WBPhenotype_0000941 a rdfs:Class ;
rdfs:label "male M lineage variant" ;
rdfs:comment "The descendants of the M precursor cell in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000809 .
obo:WBPhenotype_0001237 a rdfs:Class ;
rdfs:label "excess axon outgrowth" ;
rdfs:comment "Any perturbation that causes an increase in the frequency of axon outgrowth compared to control. As a result, an excess number of axonal projections are generated." ;
rdfs:subClassOf obo:WBPhenotype_0000629 , obo:WBPhenotype_0001224 .
obo:WBPhenotype_0001680 a rdfs:Class ;
rdfs:label "adoption of fused vulval cell fate" ;
rdfs:comment "Vulval precursor cells forgo further cell division and fuse to the hypodermis instead of adopting their intended fate (becoming primary, secondary or tertiary vulval cells)." ;
rdfs:subClassOf obo:WBPhenotype_0001272 .
obo:GO_0031012 a rdfs:Class ;
rdfs:label "extracellular matrix" ;
rdfs:comment "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." ;
rdfs:subClassOf obo:GO_0030312 .
obo:GO_0033238 a rdfs:Class ;
rdfs:label "regulation of amine metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:CHEBI_33259 a rdfs:Class ;
rdfs:label "elemental molecular entity" ;
rdfs:comment "A molecular entity all atoms of which have the same atomic number." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:WBPhenotype_0000578 a rdfs:Class ;
rdfs:label "body axis development variant" ;
rdfs:comment "Variations in the progression of a discrete axis of an animal's anatomy over time, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000528 .
obo:CHEBI_78298 a rdfs:Class ;
rdfs:label "environmental contaminant" ;
rdfs:comment "Any minor or unwanted substance introduced into the environment that can have undesired effects." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:WBPhenotype_0001754 a rdfs:Class ;
rdfs:label "endosome to lysosome trafficking defective" ;
rdfs:comment "Contents of endosomes fail to be transported to lysosomal compartments." ;
rdfs:subClassOf obo:WBPhenotype_0001421 .
obo:GO_0090304 a rdfs:Class ;
rdfs:label "nucleic acid metabolic process" ;
rdfs:comment "Any cellular metabolic process involving nucleic acids." ;
rdfs:subClassOf obo:GO_0006139 , obo:GO_0043170 .
obo:CHEBI_59683 a rdfs:Class ;
rdfs:label "antipruritic drug" ;
rdfs:comment "A drug, usually applied topically, that relieves pruritus (itching)." ;
rdfs:subClassOf obo:CHEBI_50177 .
obo:CHEBI_171664 a rdfs:Class ;
rdfs:label "antiamoebic agent" ;
rdfs:comment "An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae." ;
rdfs:subClassOf obo:CHEBI_35442 .
obo:WBbt_0004578 a rdfs:Class ;
rdfs:label "Y cell" ;
rdfs:comment "Rectal cell at hatching, becomes PDA in hermaphrodite, postembryonic blast cell in male" ;
rdfs:subClassOf obo:WBbt_0006783 , obo:WBbt_0008182 .
obo:GO_1903538 a rdfs:Class ;
rdfs:label "regulation of meiotic cell cycle process involved in oocyte maturation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0065007 , obo:GO_2000241 .
obo:WBPhenotype_0000810 a rdfs:Class ;
rdfs:label "blast cell development variant" ;
rdfs:comment "Any variation in the progression of a blast cell (precursor cell) over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:WBPhenotype_0000683 a rdfs:Class ;
rdfs:label "masculinization of germline" ;
rdfs:comment "The germ line is sexually transformed from hermaphrodite to male. In C. elegans, XX mog animals are somatically hermaphrodite, but germ cells that normally would become oocytes are transformed into sperm." ;
rdfs:subClassOf obo:WBPhenotype_0000812 , obo:WBPhenotype_0001572 .
obo:WBPhenotype_0001226 a rdfs:Class ;
rdfs:label "commissure variant" ;
rdfs:comment "Animals display variations in the structure, organization or path of the part of the axon that forms a bridge between body regions, compared to that in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000181 .
obo:GO_0032241 a rdfs:Class ;
rdfs:label "positive regulation of nucleobase-containing compound transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032239 , obo:GO_0051050 , obo:GO_0065007 .
obo:GO_0005874 a rdfs:Class ;
rdfs:label "microtubule" ;
rdfs:comment "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." ;
rdfs:subClassOf obo:GO_0099513 .
obo:GO_0051650 a rdfs:Class ;
rdfs:label "establishment of vesicle localization" ;
rdfs:comment "The directed movement of a vesicle to a specific location." ;
rdfs:subClassOf obo:GO_0051648 , obo:GO_0051649 , obo:GO_0051656 .
obo:WBPhenotype_0002400 a rdfs:Class ;
rdfs:label "glucose intolerant" ;
rdfs:comment "Animals do not live or live poorly in the presence of glucose concentrations that normally do not have an effect on control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000027 , obo:WBPhenotype_0001072 .
obo:CHEBI_35718 a rdfs:Class ;
rdfs:label "antifungal agent" ;
rdfs:comment "An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce." ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:WBbt_0004499 a rdfs:Class ;
rdfs:label "K cell" ;
rdfs:comment "Rectal cell, postembryonic blast cell" ;
rdfs:subClassOf obo:WBbt_0006783 , obo:WBbt_0008182 .
obo:CHEBI_33567 a rdfs:Class ;
rdfs:label "catecholamine" ;
rdfs:comment "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." ;
rdfs:subClassOf obo:CHEBI_25375 , obo:CHEBI_33566 .
obo:CHEBI_26764 a rdfs:Class ;
rdfs:label "steroid hormone" ;
rdfs:comment "Any steroid that acts as hormone." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35341 .
obo:WBPhenotype_0000886 a rdfs:Class ;
rdfs:label "nematode phenotype" ;
rdfs:comment "Animals exhibit variations compared to a given control." .
obo:CHEBI_51143 a rdfs:Class ;
rdfs:label "nitrogen molecular entity" ;
rdfs:subClassOf obo:CHEBI_33302 .
obo:WBPhenotype_0001146 a rdfs:Class ;
rdfs:label "polar body size defective early emb" ;
rdfs:comment "Polar body size is abnormal in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001144 .
obo:GO_0007053 a rdfs:Class ;
rdfs:label "spindle assembly involved in male meiosis" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0051225 , obo:GO_0090306 .
obo:GO_0032107 a rdfs:Class ;
rdfs:label "regulation of response to nutrient levels" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a response to nutrient levels." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 .
obo:GO_1903561 a rdfs:Class ;
rdfs:label "extracellular vesicle" ;
rdfs:comment "Any vesicle that is part of the extracellular region." ;
rdfs:subClassOf obo:GO_0031982 , obo:GO_0065010 .
obo:GO_0044841 a rdfs:Class ;
rdfs:label "gut granule membrane" ;
rdfs:comment "The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans." ;
rdfs:subClassOf obo:GO_0030659 , obo:GO_0031090 .
obo:WBPhenotype_0002378 a rdfs:Class ;
rdfs:label "pathogen avoidance variant" ;
rdfs:comment "Variations in the characteristic movement away from specific disease causing agents (pathogens) compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001012 .
obo:CHEBI_22587 a rdfs:Class ;
rdfs:label "antiviral agent" ;
rdfs:comment "A substance that destroys or inhibits replication of viruses." ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:WBPhenotype_0001186 a rdfs:Class ;
rdfs:label "embryo delayed at pronuclear contact early emb" ;
rdfs:comment "Embryos are either delayed or arrested at pronuclear contact." ;
rdfs:subClassOf obo:WBPhenotype_0001185 .
obo:CHEBI_75787 a rdfs:Class ;
rdfs:label "prokaryotic metabolite" ;
rdfs:comment "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:CHEBI_228364 a rdfs:Class ;
rdfs:label "NMR chemical shift reference compound" ;
rdfs:comment "Any compound that produces a peak used as reference frequency in the δ chemical shift scale." ;
rdfs:subClassOf obo:CHEBI_747204 .
obo:WBPhenotype_0002293 a rdfs:Class ;
rdfs:label "body posture amplitude increased" ;
rdfs:comment "Animals exhibit variations in body posture caused by an increase in the extent of displacement measured from the mean position to an extreme position compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002291 .
obo:GO_0006325 a rdfs:Class ;
rdfs:label "chromatin organization" ;
rdfs:comment "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA." ;
rdfs:subClassOf obo:GO_0016043 .
obo:CHEBI_46849 a rdfs:Class ;
rdfs:label "piperazinium salt" ;
rdfs:subClassOf obo:CHEBI_46850 .
obo:GO_1990625 a rdfs:Class ;
rdfs:label "negative regulation of cytoplasmic translational initiation in response to stress" ;
rdfs:comment "Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0032055 , obo:GO_0032057 , obo:GO_0065007 , obo:GO_1904689 , obo:GO_1990611 .
obo:WBPhenotype_0001777 a rdfs:Class ;
rdfs:label "pre mRNA levels increased" ;
rdfs:comment "Animals exhibit an increase in the levels of nuclear mRNA species compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:CHEBI_50523 a rdfs:Class ;
rdfs:label "butenolide" ;
rdfs:comment "A γ-lactone that consists of a 2-furanone skeleton and its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_24129 , obo:CHEBI_37581 .
obo:WBPhenotype_0001769 a rdfs:Class ;
rdfs:label "cytoplasmic RNAi defective" ;
rdfs:comment "Animals fail to silence cytoplasmic-localized RNAs. Nuclear-localized RNAs may still be sensitive to RNAi." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:GO_0042579 a rdfs:Class ;
rdfs:label "microbody" ;
rdfs:comment "Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2)." ;
rdfs:subClassOf obo:GO_0043231 .
obo:GO_0000374 a rdfs:Class ;
rdfs:label "Group III intron splicing" ;
rdfs:comment "The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved." ;
rdfs:subClassOf obo:GO_0000377 .
obo:GO_0044782 a rdfs:Class ;
rdfs:label "cilium organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0120036 .
obo:GO_0048846 a rdfs:Class ;
rdfs:label "axon extension involved in axon guidance" ;
rdfs:comment "The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues." ;
rdfs:subClassOf obo:GO_0048675 .
obo:GO_0046333 a rdfs:Class ;
rdfs:label "octopamine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species." ;
rdfs:subClassOf obo:GO_0006066 , obo:GO_0018958 .
obo:GO_0050777 a rdfs:Class ;
rdfs:label "negative regulation of immune response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ;
rdfs:subClassOf obo:GO_0002683 , obo:GO_0048585 , obo:GO_0050776 , obo:GO_0065007 .
obo:WBPhenotype_0001996 a rdfs:Class ;
rdfs:label "cell cycle quiescence variant" ;
rdfs:comment "Any variation in the cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence before entering the S phase, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001995 .
obo:GO_1901879 a rdfs:Class ;
rdfs:label "regulation of protein depolymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein depolymerization." ;
rdfs:subClassOf obo:GO_0043244 , obo:GO_0065007 .
obo:GO_0090326 a rdfs:Class ;
rdfs:label "positive regulation of locomotion involved in locomotory behavior" ;
rdfs:comment "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ;
rdfs:subClassOf obo:GO_0040017 , obo:GO_0048520 , obo:GO_0050789 , obo:GO_0090325 .
obo:WBPhenotype_0001811 a rdfs:Class ;
rdfs:label "serotonin induced fat reduction variant" ;
rdfs:comment "Animals retain a significantly greater proportion of their fat upon serotonin treatment, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000024 , obo:WBPhenotype_0001232 .
obo:WBPhenotype_0000260 a rdfs:Class ;
rdfs:label "sheath cell secretion failure" ;
rdfs:comment "The regulated release of materials by sheath cells is disrupted." ;
rdfs:subClassOf obo:WBPhenotype_0000259 .
obo:WBPhenotype_0001905 a rdfs:Class ;
rdfs:label "fewer eggs laid" ;
rdfs:comment "Animals lay fewer total number of eggs over the lifetime of the animal." ;
rdfs:subClassOf obo:WBPhenotype_0000640 .
obo:WBPhenotype_0000195 a rdfs:Class ;
rdfs:label "distal tip cell migration variant" ;
rdfs:comment "Variations in the migration pattern of distal tip cells compared to control animals. In C. elegans, DTCs located on the anterior and posterior ends of the gonad primordium typically migrate in a symmetrical U-shaped pattern." ;
rdfs:subClassOf obo:WBPhenotype_0000594 .
obo:WBPhenotype_0000200 a rdfs:Class ;
rdfs:label "pericellular component development variant" ;
rdfs:comment "Variations in the progression of structures/tissues surrounding a cell over time from its initial formation to its mature form compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000518 .
obo:CHEBI_73398 a rdfs:Class ;
rdfs:label "indole skeleton" ;
rdfs:comment "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." ;
rdfs:subClassOf obo:CHEBI_73541 .
obo:GO_0009653 a rdfs:Class ;
rdfs:label "anatomical structure morphogenesis" ;
rdfs:comment "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." ;
rdfs:subClassOf obo:GO_0032502 .
obo:WBPhenotype_0002089 a rdfs:Class ;
rdfs:label "cell component morphology variant" ;
rdfs:comment "Any variation in the form or composition of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles." ;
rdfs:subClassOf obo:WBPhenotype_0000533 .
obo:WBbt_0005739 a rdfs:Class ;
rdfs:label "head" ;
rdfs:comment "anterior-most body region containing the pharynx." ;
rdfs:subClassOf obo:WBbt_0005738 .
obo:WBPhenotype_0001479 a rdfs:Class ;
rdfs:label "dauer pheromone sensation variant" ;
rdfs:comment "Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that induces dauer formation in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000132 , obo:WBPhenotype_0000305 , obo:WBPhenotype_0001847 .
obo:UBERON_0002048 a rdfs:Class .
obo:GO_0050766 a rdfs:Class ;
rdfs:label "positive regulation of phagocytosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of phagocytosis." ;
rdfs:subClassOf obo:GO_0045807 , obo:GO_0050764 , obo:GO_0065007 .
obo:CHEBI_15339 a rdfs:Class ;
rdfs:label "acceptor" ;
rdfs:comment "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:WBPhenotype_0000117 a rdfs:Class ;
rdfs:label "L1 lethal" ;
rdfs:comment "Animals die at the L1 stage of the life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000057 .
obo:CHEBI_33433 a rdfs:Class ;
rdfs:label "monoatomic halogen" ;
rdfs:subClassOf obo:CHEBI_33238 .
obo:WBls_0000819 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during L2 larval stage"@en ;
rdfs:comment "A C. elegans life stage that occurs during the L2 larval life stage" ;
rdfs:subClassOf obo:WBls_0000817 .
obo:GO_0120111 a rdfs:Class ;
rdfs:label "neuron projection cytoplasm" ;
rdfs:comment "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." ;
rdfs:subClassOf obo:GO_0005737 .
obo:WBPhenotype_0000875 a rdfs:Class ;
rdfs:label "S phase checkpoint variant" ;
rdfs:comment "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the S phase of the mitotic cell cycle, which ensures DNA replication is complete, compared to control cells." ;
rdfs:subClassOf obo:WBPhenotype_0000741 , obo:WBPhenotype_0001743 .
obo:CHEBI_79389 a rdfs:Class ;
rdfs:label "monovalent inorganic anion" ;
rdfs:comment "Any inorganic anion with a valency of one." ;
rdfs:subClassOf obo:CHEBI_24834 .
obo:CHEBI_26393 a rdfs:Class ;
rdfs:label "purine nucleoside triphosphate" ;
rdfs:subClassOf obo:CHEBI_17326 .
obo:CHEBI_17891 a rdfs:Class ;
rdfs:label "donor" ;
rdfs:comment "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:WBPhenotype_0001691 a rdfs:Class ;
rdfs:label "germ nuclei rachis" ;
rdfs:comment "Germ nuclei are misplaced in the gonad and are observed in the rachis. Sheath cells are observed protruding between these nuclei. Meiotic or mitotic specification of germ nuclei is not affected." ;
rdfs:subClassOf obo:WBPhenotype_0001940 .
obo:CHEBI_35442 a rdfs:Class ;
rdfs:label "antiparasitic agent" ;
rdfs:comment "A substance used to treat or prevent parasitic infections." ;
rdfs:subClassOf obo:CHEBI_35441 .
obo:WBPhenotype_0001732 a rdfs:Class ;
rdfs:label "organism response to pH variant" ;
rdfs:comment "Animals exhibit variations in their response and ability to survive over a range of pH conditions compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBPhenotype_0001685 a rdfs:Class ;
rdfs:label "postsynaptic region morphology variant" ;
rdfs:comment "The region opposite to the presynaptic region deviates in the structure, configuration or ratio of its components specific for receiving signals from the other side of the synapse compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000616 .
obo:GO_2000001 a rdfs:Class ;
rdfs:label "regulation of DNA damage checkpoint" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a DNA damage checkpoint." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080135 , obo:GO_1901976 .
obo:CHEBI_37734 a rdfs:Class ;
rdfs:label "phosphoric ester" ;
rdfs:subClassOf obo:CHEBI_26079 , obo:CHEBI_35701 .
obo:GO_0071705 a rdfs:Class ;
rdfs:label "nitrogen compound transport" ;
rdfs:comment "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 .
obo:WBPhenotype_0001851 a rdfs:Class ;
rdfs:label "radiation induced reproductive cell death variant" ;
rdfs:comment "Animals exhibit variations in radiation induced non-apoptotic death of multipotential precursor cells or tissues (clonogens) compared to control. Elimination of clonogens results in normal tissue damage as well as solid-tumor eradication." ;
rdfs:subClassOf obo:WBPhenotype_0001173 , obo:WBPhenotype_0001268 .
obo:CHEBI_32988 a rdfs:Class ;
rdfs:label "amide" ;
rdfs:comment "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l ≠ 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ;
rdfs:subClassOf obo:CHEBI_51143 .
obo:CHEBI_35588 a rdfs:Class ;
rdfs:label "3H-purine" ;
rdfs:comment "The 3H-tautomer of purine." ;
rdfs:subClassOf obo:CHEBI_35584 .
obo:GO_0051168 a rdfs:Class ;
rdfs:label "nuclear export" ;
rdfs:comment "The directed movement of substances out of the nucleus." ;
rdfs:subClassOf obo:GO_0006913 , obo:GO_0010496 .
obo:WBPhenotype_0002277 a rdfs:Class ;
rdfs:label "dauer lifespan extended" ;
rdfs:comment "The life span of dauer-staged animals is longer than that observed in control dauer animals." ;
rdfs:subClassOf obo:WBPhenotype_0001540 .
obo:GO_1903467 a rdfs:Class ;
rdfs:label "negative regulation of mitotic DNA replication initiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication." ;
rdfs:subClassOf obo:GO_0032297 , obo:GO_0065007 , obo:GO_1903464 , obo:GO_1903466 .
obo:WBPhenotype_0001301 a rdfs:Class ;
rdfs:label "P granule abnormal" ;
rdfs:comment "Localization or structural appearance of P-granules is altered compared to control. P-granules are cytoplasmic structures associated with germ nuclei in the C. elegans gonad, and are localized exclusively to germ cells, or germ cell precursors, throughout the life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0001300 .
obo:GO_1902531 a rdfs:Class ;
rdfs:label "regulation of intracellular signal transduction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of intracellular signal transduction." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0065007 .
obo:WBPhenotype_0000735 a rdfs:Class ;
rdfs:label "endoreduplication of hypodermal nuclei variant" ;
rdfs:comment "Any variation in the regulated re-replication of DNA in the hypodermal cells during a single cell cycle, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000734 .
obo:WBPhenotype_0001211 a rdfs:Class ;
rdfs:label "cuticle integrity variant" ;
rdfs:comment "The physical strength or function of the cuticle varies from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001678 .
obo:GO_0010038 a rdfs:Class ;
rdfs:label "response to metal ion" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." ;
rdfs:subClassOf obo:GO_0042221 .
obo:WBPhenotype_0001400 a rdfs:Class ;
rdfs:label "level of protein expression variant" ;
rdfs:comment "Animals exhibit variations in the measured expression of a protein compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000112 .
obo:WBPhenotype_0000775 a rdfs:Class ;
rdfs:label "meiosis variant" ;
rdfs:comment "Variations in the specialized nuclear and cytoplasmic divisions of a single diploid cell, whose specific outcome is the formation of four haploid daughter cells compared to control. Meiosis occurs during the formation of gametes." ;
rdfs:subClassOf obo:WBPhenotype_0000740 , obo:WBPhenotype_0000746 , obo:WBPhenotype_0000812 .
obo:CHEBI_52206 a rdfs:Class ;
rdfs:label "biochemical role" ;
rdfs:comment "A biological role played by the molecular entity or part thereof within a biochemical context." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:GO_0000228 a rdfs:Class ;
rdfs:label "nuclear chromosome" ;
rdfs:comment "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." ;
rdfs:subClassOf obo:GO_0005694 .
obo:WBPhenotype_0001125 a rdfs:Class ;
rdfs:label "P2 EMS synchronous division early emb" ;
rdfs:comment "P2 and EMS divide synchronously." ;
rdfs:subClassOf obo:WBPhenotype_0001120 .
obo:WBPhenotype_0000710 a rdfs:Class ;
rdfs:label "intestinal morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000598 , obo:WBPhenotype_0002553 .
obo:CHEBI_23994 a rdfs:Class ;
rdfs:label "ethyl methanesulfonate" ;
rdfs:comment "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25223 .
obo:WBPhenotype_0001168 a rdfs:Class ;
rdfs:label "pseudocleavage absent early emb" ;
rdfs:comment "No pseudocleavage is observed before or during pronuclear migration." ;
rdfs:subClassOf obo:WBPhenotype_0001167 .
obo:WBPhenotype_0002310 a rdfs:Class ;
rdfs:label "pausing increased" ;
rdfs:comment "Animals exhibit an increase in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002308 .
obo:PATO_0002016 a rdfs:Class ;
rdfs:label "magnitude" ;
rdfs:subClassOf obo:PATO_0000068 .
obo:WBPhenotype_0001659 a rdfs:Class ;
rdfs:label "spermatheca morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the somatic gonad structure that connects the distal gonad arm to the uterus compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000977 .
obo:GO_0009790 a rdfs:Class ;
rdfs:label "embryo development" ;
rdfs:comment "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." ;
rdfs:subClassOf obo:GO_0007275 .
obo:GO_0007613 a rdfs:Class ;
rdfs:label "memory" ;
rdfs:comment "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." ;
rdfs:subClassOf obo:GO_0007611 .
obo:GO_0048878 a rdfs:Class ;
rdfs:label "chemical homeostasis" ;
rdfs:comment "Any biological process involved in the maintenance of an internal steady state of a chemical." ;
rdfs:subClassOf obo:GO_0042592 .
obo:WBPhenotype_0001916 a rdfs:Class ;
rdfs:label "increased pathogen survival" ;
rdfs:comment "Pathogens internally associated with the animal exhibit an increase in survival compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001819 .
obo:CHEBI_64911 a rdfs:Class ;
rdfs:label "antimitotic" ;
rdfs:comment "Any compound that inhibits cell division (mitosis)." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:GO_1902369 a rdfs:Class ;
rdfs:label "negative regulation of RNA catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0051253 , obo:GO_0065007 .
obo:WBPhenotype_0002413 a rdfs:Class ;
rdfs:label "multiple nuclei" ;
rdfs:comment "Animals have more than one nucleus in a particular cell type." ;
rdfs:subClassOf obo:WBPhenotype_0001894 .
obo:GO_0044093 a rdfs:Class ;
rdfs:label "positive regulation of molecular function" ;
rdfs:comment "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:GO_0030054 a rdfs:Class ;
rdfs:label "cell junction" ;
rdfs:comment "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0002649 a rdfs:Class ;
rdfs:label "egg laying response to chemical abnormal"@en ;
rdfs:comment "Characteristic response to chemicals with respect to egg-laying behavior varies compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:GO_0048469 a rdfs:Class ;
rdfs:label "cell maturation" ;
rdfs:comment "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0048869 , obo:GO_0071695 .
obo:WBPhenotype_0002373 a rdfs:Class ;
rdfs:label "conditional attraction to bacterial lawn" ;
rdfs:comment "Animals show a stronger preference for a particular bacterium that has been grown under conditions that differ from a control lawn." ;
rdfs:subClassOf obo:WBPhenotype_0000659 , obo:WBPhenotype_0002545 .
obo:WBPhenotype_0000891 a rdfs:Class ;
rdfs:label "clear adult" ;
rdfs:comment "Adult animals appear unusually transparent when compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000346 , obo:WBPhenotype_0001010 .
obo:WBPhenotype_0001490 a rdfs:Class ;
rdfs:label "obsolete posterior region morphology abnormal" ;
rdfs:comment "OBSOLETE." .
obo:GO_0001706 a rdfs:Class ;
rdfs:label "endoderm formation" ;
rdfs:comment "The formation of the endoderm during gastrulation." ;
rdfs:subClassOf obo:GO_0001704 .
obo:CHEBI_50112 a rdfs:Class ;
rdfs:label "sex hormone" ;
rdfs:comment "Any hormone that is responsible for controlling sexual characteristics and reproductive function." ;
rdfs:subClassOf obo:CHEBI_24621 .
obo:WBPhenotype_0001098 a rdfs:Class ;
rdfs:label "no rectum" ;
rdfs:comment "Animals lack the passage connecting the posterior intestine to the rectal valve." ;
rdfs:subClassOf obo:WBPhenotype_0000910 .
obo:NCBITaxon_6237 a rdfs:Class .
obo:CHEBI_30413 a rdfs:Class ;
rdfs:label "heme" ;
rdfs:comment "A heme is any tetrapyrrolic chelate of iron." ;
rdfs:subClassOf obo:CHEBI_25216 , obo:CHEBI_33892 .
obo:WBPhenotype_0000059 a rdfs:Class ;
rdfs:label "larval arrest" ;
rdfs:comment "The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." ;
rdfs:subClassOf obo:WBPhenotype_0000750 , obo:WBPhenotype_0001016 .
obo:CHEBI_47867 a rdfs:Class ;
rdfs:label "indicator" ;
rdfs:comment "Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_2000622 a rdfs:Class ;
rdfs:label "regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay." ;
rdfs:subClassOf obo:GO_0061013 , obo:GO_0065007 .
obo:CHEBI_46775 a rdfs:Class ;
rdfs:label "N-alkylpyrrolidine" ;
rdfs:subClassOf obo:CHEBI_38260 , obo:CHEBI_50996 .
obo:WBPhenotype_0000968 a rdfs:Class ;
rdfs:label "tail spike variant" ;
rdfs:comment "Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the tail compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000073 , obo:WBPhenotype_0002558 .
obo:GO_1905851 a rdfs:Class ;
rdfs:label "negative regulation of backward locomotion" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion." ;
rdfs:subClassOf obo:GO_0040013 , obo:GO_0043058 , obo:GO_0065007 .
obo:GO_1902010 a rdfs:Class ;
rdfs:label "negative regulation of translation in response to endoplasmic reticulum stress" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." ;
rdfs:subClassOf obo:GO_0032055 , obo:GO_0036490 , obo:GO_0065007 .
obo:GO_1901033 a rdfs:Class ;
rdfs:label "positive regulation of response to reactive oxygen species" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901031 , obo:GO_1902884 .
obo:WBPhenotype_0001789 a rdfs:Class ;
rdfs:label "temperature influenced life span variant" ;
rdfs:comment "Life span of the animal is not influenced by changes in temperature in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000039 , obo:WBPhenotype_0000146 .
obo:GO_0050793 a rdfs:Class ;
rdfs:label "regulation of developmental process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:GO_0019216 a rdfs:Class ;
rdfs:label "regulation of lipid metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080090 .
obo:GO_0010970 a rdfs:Class ;
rdfs:label "transport along microtubule" ;
rdfs:comment "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." ;
rdfs:subClassOf obo:GO_0007018 , obo:GO_0030705 , obo:GO_0099111 .
obo:WBPhenotype_0000102 a rdfs:Class ;
rdfs:label "presynaptic vesicle cluster variant" ;
rdfs:comment "Animals display variations in the organization, accumulation or distribution of transmitter-containing membrane-bound organelles (synaptic vesicles) compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000846 , obo:WBPhenotype_0001321 .
obo:CHEBI_33484 a rdfs:Class ;
rdfs:label "chalcogen oxoacid" ;
rdfs:subClassOf obo:CHEBI_24833 .
obo:WBPhenotype_0000444 a rdfs:Class ;
rdfs:label "bursa elongated" ;
rdfs:comment "The length of the adult male tail, including the lateral fan and rays, is extended compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000342 .
obo:PATO_0002056 a rdfs:Class ;
rdfs:label "decreased fragility" ;
rdfs:comment "A fragility which is relatively low." ;
rdfs:subClassOf obo:PATO_0001362 , obo:PATO_0002303 .
obo:CHEBI_59777 a rdfs:Class ;
rdfs:label "ketal" ;
rdfs:comment "An acetal of formula R2C(OR)2 (R ≠ H) derived from a ketone by replacement of the oxo group by two hydrocarbyloxy groups. The class name 'ketals', once abandoned by IUPAC, has been reinstated as a subclass of acetals." ;
rdfs:subClassOf obo:CHEBI_59769 .
obo:GO_0036465 a rdfs:Class ;
rdfs:label "synaptic vesicle recycling" ;
rdfs:comment "The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0051649 .
obo:WBPhenotype_0001468 a rdfs:Class ;
rdfs:label "benzaldehyde chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of benzaldehyde. In C. elegans, at specific concentrations, benzaldehyde is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001467 .
obo:CHEBI_22313 a rdfs:Class ;
rdfs:label "alkaline earth metal atom" ;
rdfs:subClassOf obo:CHEBI_33318 , obo:CHEBI_33521 , obo:CHEBI_33559 .
obo:GO_0000963 a rdfs:Class ;
rdfs:label "mitochondrial RNA processing" ;
rdfs:comment "The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion." ;
rdfs:subClassOf obo:GO_0006396 , obo:GO_0140053 .
obo:CHEBI_22927 a rdfs:Class ;
rdfs:label "bromine atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_24473 .
obo:WBbt_0004799 a rdfs:Class ;
rdfs:label "F cell" ;
rdfs:comment "Rectal cell, blast cell in male" ;
rdfs:subClassOf obo:WBbt_0006783 , obo:WBbt_0008182 .
obo:CHEBI_4781 a rdfs:Class ;
rdfs:label "emetine" ;
rdfs:comment "A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties." ;
rdfs:subClassOf obo:CHEBI_24921 , obo:CHEBI_61692 .
obo:CHEBI_26432 a rdfs:Class ;
rdfs:label "pyrimidine nucleobase" ;
rdfs:comment "A nucleobase whose skeleton is derived from pyrimidine." ;
rdfs:subClassOf obo:CHEBI_18282 , obo:CHEBI_39447 .
obo:GO_0006401 a rdfs:Class ;
rdfs:label "RNA catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ;
rdfs:subClassOf obo:GO_0016070 , obo:GO_0141188 .
obo:CHEBI_35381 a rdfs:Class ;
rdfs:label "monosaccharide" ;
rdfs:comment "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H‒[CHOH]n‒C(=O)[CHOH]m‒H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." ;
rdfs:subClassOf obo:CHEBI_16646 .
obo:WBPhenotype_0000868 a rdfs:Class ;
rdfs:label "paralyzed body" ;
rdfs:comment "All parts of the animal are immobilized except for the head." ;
rdfs:subClassOf obo:WBPhenotype_0000644 .
obo:CHEBI_50317 a rdfs:Class ;
rdfs:label "iodonium" ;
rdfs:subClassOf obo:CHEBI_50313 .
obo:WBPhenotype_0002093 a rdfs:Class ;
rdfs:label "recycling endosome morphology variant" ;
rdfs:comment "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
rdfs:subClassOf obo:WBPhenotype_0002090 .
obo:WBPhenotype_0001349 a rdfs:Class ;
rdfs:label "protein phosphorylation variant" ;
rdfs:comment "Variations in the processes that incorporate phosphate groups to one or more amino acids within a protein, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001382 .
obo:PATO_0001596 a rdfs:Class ;
rdfs:label "increased depth" ;
rdfs:comment "A depth quality which is relatively high." ;
rdfs:subClassOf obo:PATO_0000586 , obo:PATO_0001595 .
obo:CHEBI_83813 a rdfs:Class ;
rdfs:label "proteinogenic amino acid" ;
rdfs:comment "Any of the 23 α-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:WBPhenotype_0001421 a rdfs:Class ;
rdfs:label "endocytic transport variant" ;
rdfs:comment "Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001752 .
obo:GO_0070013 a rdfs:Class ;
rdfs:label "intracellular organelle lumen" ;
rdfs:comment "An organelle lumen that is part of an intracellular organelle." ;
rdfs:subClassOf obo:GO_0031974 , obo:GO_0043233 .
obo:GO_0051326 a rdfs:Class ;
rdfs:label "telophase" ;
rdfs:comment "The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." ;
rdfs:subClassOf obo:GO_0022403 .
obo:GO_0033047 a rdfs:Class ;
rdfs:label "regulation of mitotic sister chromatid segregation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." ;
rdfs:subClassOf obo:GO_0033045 , obo:GO_0065007 .
obo:CHEBI_32952 a rdfs:Class ;
rdfs:label "amine" ;
rdfs:comment "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:GO_0099111 a rdfs:Class ;
rdfs:label "microtubule-based transport" ;
rdfs:comment "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." ;
rdfs:subClassOf obo:GO_0006810 .
obo:WBPhenotype_0001594 a rdfs:Class ;
rdfs:label "germline transgene silencing variant" ;
rdfs:comment "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the germline, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001593 .
obo:GO_0044087 a rdfs:Class ;
rdfs:label "regulation of cellular component biogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:CHEBI_37246 a rdfs:Class ;
rdfs:label "elemental sodium" ;
rdfs:subClassOf obo:CHEBI_26712 .
obo:CHEBI_137041 a rdfs:Class ;
rdfs:label "quinine(1+)" ;
rdfs:comment "The monoprotonated form of quinine, the predominant species at pH7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_51323 .
obo:GO_1903370 a rdfs:Class ;
rdfs:label "positive regulation of foraging behavior" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of foraging behavior." ;
rdfs:subClassOf obo:GO_0048520 , obo:GO_0065007 , obo:GO_1903368 .
obo:WBPhenotype_0000931 a rdfs:Class ;
rdfs:label "bisphenol A response variant" ;
rdfs:comment "Animals exhibit variations in their response to bisphenol A compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:WBPhenotype_0002244 a rdfs:Class ;
rdfs:label "arsenic hypersensitive" ;
rdfs:comment "Animals respond to arsenic at a lower concentration or at a shorter exposure time compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000591 , obo:WBPhenotype_0001918 .
obo:GO_0033036 a rdfs:Class ;
rdfs:label "macromolecule localization" ;
rdfs:comment "Any process in which a macromolecule is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051179 .
obo:CHEBI_33708 a rdfs:Class ;
rdfs:label "amino-acid residue" ;
rdfs:comment "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:GO_0140098 a rdfs:Class ;
rdfs:label "catalytic activity, acting on RNA" ;
rdfs:comment "Catalytic activity that acts to modify RNA." ;
rdfs:subClassOf obo:GO_0140640 .
obo:WBPhenotype_0001516 a rdfs:Class ;
rdfs:label "helical cuticle" ;
rdfs:comment "Animals exhibit a helically twisted cuticle. In practice the degree of twisting is measured as the number of helical twists the alae make about anterior/posterior axis of the animal." ;
rdfs:subClassOf obo:WBPhenotype_0000948 .
obo:WBls_0000038 a rdfs:Class ;
rdfs:label "L4 larva Ce" ;
rdfs:comment "The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch." ;
rdfs:subClassOf obo:WBls_0000109 , obo:WBls_0000821 .
obo:WBPhenotype_0004024 a rdfs:Class ;
rdfs:label "wavelength of movement variant" ;
rdfs:comment "Any variation in the distance in the line of advance of a body wave from any one point to the next point of corresponding phase compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0004018 .
obo:PATO_0000080 a rdfs:Class ;
rdfs:label "amplitude" ;
rdfs:comment "A physical quality of a process inhering in a bearer by virtue of the size of the bearer's maximum displacement from the 'normal' position, when periodic motion is taking place." ;
rdfs:subClassOf obo:PATO_0002062 .
obo:GO_0090235 a rdfs:Class ;
rdfs:label "regulation of metaphase plate congression" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle." ;
rdfs:subClassOf obo:GO_0032879 , obo:GO_0065007 .
obo:CHEBI_59059 a rdfs:Class ;
rdfs:label "methyl isocyanate" ;
rdfs:comment "The isocyanate that is methane modified by a single isocyanato substituent." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_53212 .
obo:GO_0031345 a rdfs:Class ;
rdfs:label "negative regulation of cell projection organization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ;
rdfs:subClassOf obo:GO_0031344 , obo:GO_0051129 , obo:GO_0065007 .
obo:WBPhenotype_0002416 a rdfs:Class ;
rdfs:label "spindle position variant" ;
rdfs:comment "Any variation in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002414 .
obo:WBPhenotype_0001446 a rdfs:Class ;
rdfs:label "sodium chloride adaptation defective" ;
rdfs:comment "Animals do not exhibit characteristic chemoattractive desensitization to sodium chloride in a time-concentration dependent and reversible manner compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001444 .
obo:GO_0001556 a rdfs:Class ;
rdfs:label "oocyte maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0048469 .
obo:CHEBI_53212 a rdfs:Class ;
rdfs:label "isocyanates" ;
rdfs:comment "Organonitrogen compounds that are derivatives of isocyanic acid; compounds containing the isocyanate functional group ‒N=C=O (as opposed to the cyanate group, -O-C≡N)." ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_36963 .
obo:WBPhenotype_0000236 a rdfs:Class ;
rdfs:label "dopamine catabolism defective" ;
rdfs:comment "Animals are unable to carry outany chemical reaction or pathway resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ;
rdfs:subClassOf obo:WBPhenotype_0000233 .
obo:GO_1904290 a rdfs:Class ;
rdfs:label "negative regulation of mitotic DNA damage checkpoint" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0045931 , obo:GO_0065007 , obo:GO_1904289 , obo:GO_2000002 .
obo:WBPhenotype_0001956 a rdfs:Class ;
rdfs:label "oocytes lack nucleus" ;
rdfs:comment "Haploid female germ cells (oocytes) lack a nucleus." ;
rdfs:subClassOf obo:WBPhenotype_0000186 , obo:WBPhenotype_0001260 .
obo:WBPhenotype_0001023 a rdfs:Class ;
rdfs:label "sexually dimorphic morphology variant" ;
rdfs:comment "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000535 .
obo:GO_0042493 a rdfs:Class .
obo:GO_0032091 a rdfs:Class ;
rdfs:label "negative regulation of protein binding" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding." ;
rdfs:subClassOf obo:GO_0043393 , obo:GO_0051100 , obo:GO_0065007 .
obo:WBPhenotype_0001749 a rdfs:Class ;
rdfs:label "zinc toxicity hypersensitive" ;
rdfs:comment "The toxic response to zinc occurs at a lower concentration or a shorter exposure compared to control animals. In C. elegans hypersensitive animals exhibit delayed development or lethality at concentrations of zinc (e.g. ZnSO4), which has little or no effect on control worms." ;
rdfs:subClassOf obo:WBPhenotype_0001747 , obo:WBPhenotype_0001918 .
obo:GO_1903743 a rdfs:Class ;
rdfs:label "negative regulation of anterograde synaptic vesicle transport" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901609 , obo:GO_1902804 , obo:GO_1903742 .
obo:GO_0010564 a rdfs:Class ;
rdfs:label "regulation of cell cycle process" ;
rdfs:comment "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ;
rdfs:subClassOf obo:GO_0051726 , obo:GO_0065007 .
obo:WBPhenotype_0002614 a rdfs:Class ;
rdfs:label "derepression of heterchromatic gene silencing"@en ;
rdfs:comment "Genes normally silenced within heterochromatin are abnoramally de-repressed and exhibit expression, unlike controls." ;
rdfs:subClassOf obo:WBPhenotype_0000135 .
obo:WBPhenotype_0002262 a rdfs:Class ;
rdfs:label "postsynaptic component localization variant" ;
rdfs:comment "Animals display variations in the distribution of the constituents of the postsynaptic side of the active zone, compared to control animals, that are required for receiving signals from the presynaptic side." ;
rdfs:subClassOf obo:WBPhenotype_0001685 .
obo:GO_1900103 a rdfs:Class ;
rdfs:label "positive regulation of endoplasmic reticulum unfolded protein response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900101 , obo:GO_1902533 , obo:GO_1905898 .
obo:WBPhenotype_0001709 a rdfs:Class ;
rdfs:label "rhythmic tolerance to stress variant" ;
rdfs:comment "Animals exhibit variations in light/dark cycle recurrence of reactions to stress conditions compared to that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 , obo:WBPhenotype_0001711 .
obo:GO_0061660 a rdfs:Class ;
rdfs:label "Atg12 ligase activity" ;
rdfs:comment "Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate." ;
rdfs:subClassOf obo:GO_0019777 , obo:GO_0061659 .
obo:WBPhenotype_0000526 a rdfs:Class ;
rdfs:label "cell pigmentation phenotype" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a cell." ;
rdfs:subClassOf obo:WBPhenotype_0000521 , obo:WBPhenotype_0000533 .
obo:CHEBI_50995 a rdfs:Class ;
rdfs:label "secondary amino compound" ;
rdfs:comment "A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:WBPhenotype_0000489 a rdfs:Class ;
rdfs:label "chloroquine resistant" ;
rdfs:comment "Animals fail to respond to the concentration of chloroquine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 .
obo:GO_0008285 a rdfs:Class ;
rdfs:label "negative regulation of cell population proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0048523 , obo:GO_0065007 .
obo:GO_0099513 a rdfs:Class ;
rdfs:label "polymeric cytoskeletal fiber" ;
rdfs:comment "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." ;
rdfs:subClassOf obo:GO_0099512 .
obo:GO_0050685 a rdfs:Class ;
rdfs:label "positive regulation of mRNA processing" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mRNA processing." ;
rdfs:subClassOf obo:GO_0050684 , obo:GO_0065007 , obo:GO_1903313 .
obo:WBPhenotype_0001501 a rdfs:Class ;
rdfs:label "odorant discrimination defective" ;
rdfs:comment "Animals fail to discriminate between distinct odorants." ;
rdfs:subClassOf obo:WBPhenotype_0001048 .
obo:CHEBI_88184 a rdfs:Class ;
rdfs:label "metal allergen" ;
rdfs:comment "Any metal which causes the onset of an allergic reaction." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33521 .
obo:CL_1000272 a rdfs:Class ;
rdfs:label "lung secretory cell" ;
rdfs:comment "Any secretory cell that is part of some lung." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000255 .
obo:CHEBI_25413 a rdfs:Class ;
rdfs:label "monounsaturated fatty acid" ;
rdfs:comment "Any fatty acid with one double or triple bond in the fatty acid chain and singly bonded carbon atoms in the rest of the chain. MUFAs have positive effects on the cardiovascular system, and in diabetes treatment." ;
rdfs:subClassOf obo:CHEBI_27208 .
obo:GO_2000384 a rdfs:Class ;
rdfs:label "negative regulation of ectoderm development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0065007 , obo:GO_2000383 .
obo:WBls_0000107 a rdfs:Class ;
rdfs:label "L2 larval stage" ;
rdfs:comment "The second stage larva of nematodes." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000105 .
obo:GO_0006915 a rdfs:Class ;
rdfs:label "apoptotic process" ;
rdfs:comment "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." ;
rdfs:subClassOf obo:GO_0012501 .
obo:WBPhenotype_0002109 a rdfs:Class ;
rdfs:label "drug susceptible" ;
rdfs:comment "Animals are affected by exposure to the drug." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0002053 a rdfs:Class ;
rdfs:label "ivermectin resistant" ;
rdfs:comment "Animals fail to respond to or exhibit an attenuated response to ivermectin under conditions that elicits a response in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 , obo:WBPhenotype_0001856 .
obo:WBPhenotype_0001620 a rdfs:Class ;
rdfs:label "organism oxidative stress response variant" ;
rdfs:comment "Animals exhibit variations in their response to oxidative stress compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBbt_0005756 a rdfs:Class ;
rdfs:label "basal lamina" ;
rdfs:subClassOf obo:WBbt_0005732 .
obo:WBPhenotype_0002540 a rdfs:Class ;
rdfs:label "lawn leaving reduced"@en ;
rdfs:comment "Animals exhibit a reduced rate of lawn/food leaving events, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001983 .
obo:CHEBI_16670 a rdfs:Class ;
rdfs:label "peptide" ;
rdfs:comment "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from α-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ;
rdfs:subClassOf obo:CHEBI_37622 , obo:CHEBI_50047 .
obo:GO_1902101 a rdfs:Class ;
rdfs:label "positive regulation of metaphase/anaphase transition of cell cycle" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901989 , obo:GO_1902099 .
obo:CHEBI_23447 a rdfs:Class ;
rdfs:label "cyclic nucleotide" ;
rdfs:subClassOf obo:CHEBI_36976 .
obo:WBPhenotype_0001157 a rdfs:Class ;
rdfs:label "pronuclear breakdown defective early emb" ;
rdfs:comment "Pronuclear breakdown is atypical in the inviable embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001151 .
obo:CHEBI_37622 a rdfs:Class ;
rdfs:label "carboxamide" ;
rdfs:comment "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the ‒C(=O)NH2 group including its carbon atom." ;
rdfs:subClassOf obo:CHEBI_33256 , obo:CHEBI_35352 , obo:CHEBI_36963 .
obo:GO_0000132 a rdfs:Class ;
rdfs:label "establishment of mitotic spindle orientation" ;
rdfs:comment "A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures." ;
rdfs:subClassOf obo:GO_0040001 , obo:GO_0051294 .
obo:CHEBI_27563 a rdfs:Class ;
rdfs:label "arsenic atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_137980 , obo:CHEBI_33300 .
obo:WBPhenotype_0000906 a rdfs:Class ;
rdfs:label "uterine vulval cell morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) compared to control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0002108 .
obo:WBPhenotype_0002573 a rdfs:Class ;
rdfs:label "mitophagy reduced"@en ;
rdfs:comment "Animals exhibit reduced levels of mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002572 .
obo:WBPhenotype_0001719 a rdfs:Class ;
rdfs:label "unfolded protein response variant" ;
rdfs:comment "Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones." ;
rdfs:subClassOf obo:WBPhenotype_0000142 , obo:WBPhenotype_0001644 .
obo:GO_0002184 a rdfs:Class ;
rdfs:label "cytoplasmic translational termination" ;
rdfs:comment "The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon." ;
rdfs:subClassOf obo:GO_0006415 .
obo:WBPhenotype_0001320 a rdfs:Class ;
rdfs:label "endogenous synaptic amplitude variant" ;
rdfs:comment "The amplitude (magnitude) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is altered compared to control. Changes in amplitude are often interpreted as alterations of postsynaptic responsiveness to the transmitter." ;
rdfs:subClassOf obo:WBPhenotype_0001318 .
obo:CHEBI_47704 a rdfs:Class ;
rdfs:label "ammonium salt" ;
rdfs:subClassOf obo:CHEBI_35276 .
obo:WBPhenotype_0001583 a rdfs:Class ;
rdfs:label "XXX progeny" ;
rdfs:comment "Animals segregate progeny with 3 X chromosomes." ;
rdfs:subClassOf obo:WBPhenotype_0001664 .
obo:WBPhenotype_0000410 a rdfs:Class ;
rdfs:label "no defecation cycle" ;
rdfs:comment "Animals lack the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000207 .
obo:CHEBI_64577 a rdfs:Class ;
rdfs:label "flour treatment agent" ;
rdfs:comment "A food additive which is added to flour or dough to improve baking quality and/or colour." ;
rdfs:subClassOf obo:CHEBI_64047 .
obo:WBPhenotype_0000065 a rdfs:Class ;
rdfs:label "X0 lethal" ;
rdfs:comment "XO-bearing individuals die preferentially over other animals in the population. In C.elegans, X0 animals die preferentially over XX animals." ;
rdfs:subClassOf obo:WBPhenotype_0000064 .
obo:GO_0045963 a rdfs:Class ;
rdfs:label "negative regulation of dopamine metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ;
rdfs:subClassOf obo:GO_0033239 , obo:GO_0042053 , obo:GO_0065007 .
obo:GO_0002119 a rdfs:Class ;
rdfs:label "nematode larval development" ;
rdfs:comment "The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ;
rdfs:subClassOf obo:GO_0002164 .
obo:WBPhenotype_0001527 a rdfs:Class ;
rdfs:label "amphid phasmid sensillum morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head or along the tail, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000299 .
obo:WBPhenotype_0002266 a rdfs:Class ;
rdfs:label "mitochondrial content variant" ;
rdfs:comment "Animals exhibit variations in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining." ;
rdfs:subClassOf obo:WBPhenotype_0001344 .
obo:GO_0007276 a rdfs:Class ;
rdfs:label "gamete generation" ;
rdfs:comment "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." ;
rdfs:subClassOf obo:GO_0048609 .
obo:GO_0009266 a rdfs:Class ;
rdfs:label "response to temperature stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus." ;
rdfs:subClassOf obo:GO_0009628 .
obo:GO_1904688 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translational initiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0065007 , obo:GO_2000765 .
obo:GO_0031334 a rdfs:Class ;
rdfs:label "positive regulation of protein-containing complex assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein complex assembly." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0044089 , obo:GO_0051130 , obo:GO_0065007 .
obo:GO_0006887 a rdfs:Class ;
rdfs:label "exocytosis" ;
rdfs:comment "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." ;
rdfs:subClassOf obo:GO_0016192 , obo:GO_0032940 .
obo:WBPhenotype_0001674 a rdfs:Class ;
rdfs:label "telomere morphology variant" ;
rdfs:comment "Animals exhibit variations in the sequence or organization of the components of the terminal region of its chromosome, (i.e. telomere, which serves to stabilize the chromosome) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001348 .
obo:WBPhenotype_0000072 a rdfs:Class ;
rdfs:label "body morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any portion of their anatomy between the head and the tail compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000532 , obo:WBPhenotype_0000582 .
obo:GO_0031340 a rdfs:Class ;
rdfs:label "positive regulation of vesicle fusion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vesicle fusion." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0031338 , obo:GO_0051050 , obo:GO_0065007 .
obo:WBbt_0005733 a rdfs:Class ;
rdfs:label "hypodermis" ;
rdfs:comment "Epidermal layer." ;
rdfs:subClassOf obo:WBbt_0005729 .
obo:CHEBI_29919 a rdfs:Class ;
rdfs:label "hydrosulfide" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33535 .
obo:CHEBI_27848 a rdfs:Class ;
rdfs:label "alpha-L-rhamnoside" ;
rdfs:subClassOf obo:CHEBI_26547 .
obo:GO_0031111 a rdfs:Class ;
rdfs:label "negative regulation of microtubule polymerization or depolymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." ;
rdfs:subClassOf obo:GO_0031110 , obo:GO_0051494 , obo:GO_0065007 .
obo:WBPhenotype_0001067 a rdfs:Class ;
rdfs:label "active phase variant" ;
rdfs:comment "The active phase of egg-laying, the period during which animals are more likely to display multiple egg-laying events, is atypical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ;
rdfs:subClassOf obo:WBPhenotype_0001063 .
obo:WBPhenotype_0000842 a rdfs:Class ;
rdfs:label "Z4 male lineage variant" ;
rdfs:comment "Z4 descendants exhibit altered developmental programs in the male compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000838 .
obo:WBPhenotype_0000355 a rdfs:Class ;
rdfs:label "HSN differentiation precocious" ;
rdfs:comment "Specialization of HSN precursor cells to mature HSN neurons occurs at an earlier stage of development compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000354 , obo:WBPhenotype_0000439 .
obo:GO_0061736 a rdfs:Class ;
rdfs:label "engulfment of target by autophagosome" ;
rdfs:comment "The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy." ;
rdfs:subClassOf obo:GO_0010324 .
obo:WBPhenotype_0000764 a rdfs:Class ;
rdfs:label "embryonic cell organization biogenesis variant" ;
rdfs:comment "Variations in the processes that are carried out at in the embryo which results in its formation or the arrangement of constituent parts, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000749 , obo:WBPhenotype_0000763 , obo:WBPhenotype_0010002 .
obo:CHEBI_71666 a rdfs:Class ;
rdfs:label "gamma-amino acid anion" ;
rdfs:comment "An amino-acid anion in which the amino group is situated γ- to the carboxylate group." ;
rdfs:subClassOf obo:CHEBI_37022 .
obo:GO_0006448 a rdfs:Class ;
rdfs:label "regulation of translational elongation" ;
rdfs:comment "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:WBPhenotype_0002528 a rdfs:Class ;
rdfs:label "miRNA biogenesis defective"@en ;
rdfs:comment "Animals (or cells) exhibit defects in the ability to produce mature microRNAs (miRNAs) from a miRNA locus. The defects could be at the level of miRNA transcription, pri-miRNA processing, and/or pre-miRNA processing." ;
rdfs:subClassOf obo:WBPhenotype_0001779 .
obo:GO_0032774 a rdfs:Class ;
rdfs:label "RNA biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." ;
rdfs:subClassOf obo:GO_0016070 , obo:GO_0141187 .
obo:GO_0032065 a rdfs:Class ;
rdfs:label "maintenance of protein location in cell cortex" ;
rdfs:comment "A process in which a protein or protein complex is maintained in a specific location in the cell cortex." ;
rdfs:subClassOf obo:GO_0032507 , obo:GO_0045185 .
obo:GO_0098930 a rdfs:Class ;
rdfs:label "axonal transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules in axons." ;
rdfs:subClassOf obo:GO_0008088 .
obo:GO_2000243 a rdfs:Class ;
rdfs:label "positive regulation of reproductive process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of reproductive process." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0065007 , obo:GO_2000241 .
obo:PATO_0000150 a rdfs:Class ;
rdfs:label "texture" ;
rdfs:comment "A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:CHEBI_33552 a rdfs:Class ;
rdfs:label "sulfonic acid derivative" ;
rdfs:subClassOf obo:CHEBI_33424 .
obo:GO_0043053 a rdfs:Class ;
rdfs:label "dauer entry" ;
rdfs:comment "Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development." ;
rdfs:subClassOf obo:GO_0055115 .
obo:GO_0060795 a rdfs:Class ;
rdfs:label "cell fate commitment involved in formation of primary germ layer" ;
rdfs:comment "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." ;
rdfs:subClassOf obo:GO_0045165 .
obo:WBPhenotype_0000537 a rdfs:Class ;
rdfs:label "obsolete synaptic input abnormal" ;
rdfs:comment "OBSOLETE." .
obo:GO_0042551 a rdfs:Class ;
rdfs:label "neuron maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0048469 .
obo:WBPhenotype_0002424 a rdfs:Class ;
rdfs:label "anoxia response variant" ;
rdfs:comment "Animals exhibit variations in response to anoxia, trace oxygen conditions, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000067 , obo:WBPhenotype_0000464 .
obo:GO_1900118 a rdfs:Class ;
rdfs:label "negative regulation of execution phase of apoptosis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0065007 , obo:GO_1900117 .
obo:GO_0045840 a rdfs:Class ;
rdfs:label "positive regulation of mitotic nuclear division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitosis." ;
rdfs:subClassOf obo:GO_0007088 , obo:GO_0051785 , obo:GO_0065007 , obo:GO_0090068 .
obo:PATO_0000470 a rdfs:Class ;
rdfs:label "increased amount" ;
rdfs:comment "An amount which is relatively high." ;
rdfs:subClassOf obo:PATO_0000070 , obo:PATO_0000467 , obo:PATO_0002300 .
obo:CHEBI_27207 a rdfs:Class ;
rdfs:label "univalent carboacyl group" ;
rdfs:comment "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." ;
rdfs:subClassOf obo:CHEBI_37838 .
obo:GO_0010721 a rdfs:Class ;
rdfs:label "negative regulation of cell development" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0060284 , obo:GO_0065007 .
obo:WBPhenotype_0002449 a rdfs:Class ;
rdfs:label "reduced acute pharyngeal pumping response to light" ;
rdfs:comment "Animals exhibit a reduced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a lesser extent than in controls during the first 0-5 seconds after light exposure onset." ;
rdfs:subClassOf obo:WBPhenotype_0002447 .
obo:GO_1902974 a rdfs:Class ;
rdfs:label "meiotic DNA replication initiation" ;
rdfs:comment "Any DNA replication initiation involved in meiotic cell cycle DNA replication." ;
rdfs:subClassOf obo:GO_1902315 , obo:GO_1903046 .
obo:WBls_0000056 a rdfs:Class ;
rdfs:label "adult male Ce" ;
rdfs:comment "The stage after an male animal is fully-developed and reaches maturity." ;
rdfs:subClassOf obo:WBls_0000041 .
obo:WBPhenotype_0001457 a rdfs:Class ;
rdfs:label "bromide chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of bromide. In C. elegans, bromide is typically an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001052 .
obo:CHEBI_51371 a rdfs:Class ;
rdfs:label "muscle relaxant" ;
rdfs:comment "A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis." ;
rdfs:subClassOf obo:CHEBI_51372 .
obo:WBPhenotype_0001920 a rdfs:Class ;
rdfs:label "twisted pharynx" ;
rdfs:comment "The growth of pharyngeal components occurs in a radial fashion around the longitudinal axis of the worm as demonstrated by bent radial contractile arrays within the pharyngeal muscle cells. The defect is more pronounced as development progresses resulting in a more obvious twisting phenotype. Depending on the allele, the twist can be right-handed or left-handed" ;
rdfs:subClassOf obo:WBPhenotype_0000707 .
obo:WBbt_0005773 a rdfs:Class ;
rdfs:label "rectum" ;
rdfs:comment "The passageway in the hindgut between the posterior intestine, the rectal valve and the opening to the exterior." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:GO_1904748 a rdfs:Class ;
rdfs:label "regulation of apoptotic process involved in development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of apoptotic process involved in development." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0050793 , obo:GO_0065007 .
obo:WBPhenotype_0002212 a rdfs:Class ;
rdfs:label "amphid neuron dye filling defect" ;
rdfs:comment "Animals exhibit defects in dye-filling of the neuronal cells of the amphid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." ;
rdfs:subClassOf obo:WBPhenotype_0000256 , obo:WBPhenotype_0002535 .
obo:GO_0061062 a rdfs:Class ;
rdfs:label "regulation of nematode larval development" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ;
rdfs:subClassOf obo:GO_0048580 , obo:GO_0065007 .
obo:CHEBI_39215 a rdfs:Class ;
rdfs:label "antibiotic pesticide" ;
rdfs:subClassOf obo:CHEBI_25944 , obo:CHEBI_33281 .
obo:BFO_0000019 a rdfs:Class ;
rdfs:label "quality"@en ;
rdfs:subClassOf obo:BFO_0000020 .
obo:WBPhenotype_0001827 a rdfs:Class ;
rdfs:label "RNA metabolism variant" ;
rdfs:comment "Variations in any process that involves the maintenance, biosynthesis or accumulation of RNA in the organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000463 , obo:WBPhenotype_0000585 .
obo:WBPhenotype_0001410 a rdfs:Class ;
rdfs:label "protein expression absent" ;
rdfs:comment "Animals fail to express a given protein or class of proteins." ;
rdfs:subClassOf obo:WBPhenotype_0000120 .
obo:GO_0009889 a rdfs:Class ;
rdfs:label "regulation of biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:WBPhenotype_0001292 a rdfs:Class ;
rdfs:label "body wall muscle physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the body wall muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000990 .
obo:WBPhenotype_0002603 a rdfs:Class ;
rdfs:label "protein toxicity response abnormal"@en ;
rdfs:comment "Animals exhibit an abnormal response to toxic proteins, either via exposure in the environment or expressed within the organism, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:WBPhenotype_0000979 a rdfs:Class ;
rdfs:label "spermatheca dilation defective" ;
rdfs:comment "Animals exhibit defects in any physical or chemical process involved in the dilation of the distal spermatheca which is required for the oocyte exit from the gonad arm." ;
rdfs:subClassOf obo:WBPhenotype_0000978 .
obo:WBPhenotype_0002562 a rdfs:Class ;
rdfs:label "lysosome homeostasis abnormal"@en ;
rdfs:comment "Cells exhibit variations or abnormalities in their maintenance of lysosome function, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0001738 a rdfs:Class ;
rdfs:label "ammonium chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to ammonium compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000015 .
obo:WBPhenotype_0002037 a rdfs:Class ;
rdfs:label "nuclear envelope organization variant" ;
rdfs:comment "The appearance and association of components along the double lipid bilayer enclosing the nucleus differs from controls. The NE separates nuclear contents from the rest of the cytoplasm and includes the intermembrane space, perinuclear space." ;
rdfs:subClassOf obo:WBPhenotype_0001028 .
obo:GO_1905898 a rdfs:Class ;
rdfs:label "positive regulation of response to endoplasmic reticulum stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0048584 , obo:GO_0065007 , obo:GO_1905897 .
obo:WBPhenotype_0000998 a rdfs:Class ;
rdfs:label "thermophilic" ;
rdfs:comment "Animals tend to track and stay within high temperature environments." ;
rdfs:subClassOf obo:WBPhenotype_0000478 .
obo:GO_0040002 a rdfs:Class ;
rdfs:label "collagen and cuticulin-based cuticle development" ;
rdfs:comment "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans." ;
rdfs:subClassOf obo:GO_0042335 .
obo:WBPhenotype_0004002 a rdfs:Class ;
rdfs:label "attraction signal defective" ;
rdfs:comment "Animals exhibit defects in the production of the sensory signal to attract males." ;
rdfs:subClassOf obo:WBPhenotype_0004015 .
obo:WBPhenotype_0000920 a rdfs:Class ;
rdfs:label "obsolete body wall muscle cell development variant" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0002517 a rdfs:Class ;
rdfs:label "burrowing assay distance reduced"@en ;
rdfs:comment "Animals exhibit a reduction, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Reductions in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect deficits in neuromuscular efficacy of locomotion." ;
rdfs:subClassOf obo:WBPhenotype_0002516 .
obo:WBPhenotype_0001778 a rdfs:Class ;
rdfs:label "nuclear RNAi defective" ;
rdfs:comment "Animals fail to silence nuclear-localized RNAs. Animals still retain sensitivity to RNAi for those RNAs located outside of the nucleus." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:WBPhenotype_0002438 a rdfs:Class ;
rdfs:label "repetitive transgene expression reduced" ;
rdfs:comment "Animals exhibit reduced expression of repetitive exogenous DNA compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002437 .
obo:CHEBI_50903 a rdfs:Class ;
rdfs:label "carcinogenic agent" ;
rdfs:comment "A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:WBPhenotype_0000211 a rdfs:Class ;
rdfs:label "defecation contraction asynchronous" ;
rdfs:comment "The rhythmic contractions of the muscles coordinating the elimination of gut contents are no longer synchronized compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000210 .
obo:GO_0023056 a rdfs:Class ;
rdfs:label "positive regulation of signaling" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." ;
rdfs:subClassOf obo:GO_0023051 , obo:GO_0048518 , obo:GO_0065007 .
obo:WBPhenotype_0000952 a rdfs:Class ;
rdfs:label "anterior ganglion development variant" ;
rdfs:comment "Any variation in the progression of a cluster of neuron somata located close to the nerve ring over time from its initial formation to its mature form compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000943 .
obo:WBPhenotype_0001967 a rdfs:Class ;
rdfs:label "meiotic chromatin reorganization variant" ;
rdfs:comment "Animals differ from control animals in the length of or mechanics of the steps that culminate in the preservation and subsequent disassembly of the synaptonemal complex, the specification of bivalent arms, and proper cohesion of sister chromatids." ;
rdfs:subClassOf obo:WBPhenotype_0002012 .
obo:PATO_0001496 a rdfs:Class ;
rdfs:label "brood quality" ;
rdfs:comment "A reproductive quality inhering in the young of an animal by virtue of the bearer's being cared for at one time." ;
rdfs:subClassOf obo:PATO_0001434 .
obo:WBbt_0006790 a rdfs:Class ;
rdfs:label "uterine-vulval cell" ;
rdfs:comment "monoucleate interfacial cell between the uterus and vulva (uv1-uv3), four sets total (L/R, A/P)" ;
rdfs:subClassOf obo:WBbt_0007815 , obo:WBbt_0008435 .
obo:GO_0008291 a rdfs:Class ;
rdfs:label "acetylcholine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ;
rdfs:subClassOf obo:GO_0008152 .
obo:CHEBI_35155 a rdfs:Class ;
rdfs:label "elemental calcium" ;
rdfs:subClassOf obo:CHEBI_22985 .
obo:CHEBI_83824 a rdfs:Class ;
rdfs:label "L-cysteine derivative" ;
rdfs:comment "A proteinogenic amino acid derivative resulting from the formal reaction of L-cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of L-cysteine by a heteroatom." ;
rdfs:subClassOf obo:CHEBI_23509 , obo:CHEBI_83811 .
obo:WBPhenotype_0002536 a rdfs:Class ;
rdfs:label "P granule number abnormal"@en ;
rdfs:comment "Animals exhibit germ cells with a number of P granules that differs from control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001300 .
obo:WBPhenotype_0001141 a rdfs:Class ;
rdfs:label "nucleus reforms cell division remnant early emb" ;
rdfs:comment "After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant." ;
rdfs:subClassOf obo:WBPhenotype_0001027 .
obo:WBPhenotype_0002106 a rdfs:Class ;
rdfs:label "early endosome localization variant" ;
rdfs:comment "Any variation in the subcellular localization of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002100 .
obo:WBPhenotype_0000983 a rdfs:Class ;
rdfs:label "fertilization defective" ;
rdfs:comment "Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) during sexual reproduction." ;
rdfs:subClassOf obo:WBPhenotype_0000613 .
obo:CHEBI_59806 a rdfs:Class ;
rdfs:label "(S)-nicotinium(1+)" ;
rdfs:comment "The conjugate acid of (S)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35274 .
obo:GO_0009987 a rdfs:Class ;
rdfs:label "cellular process" ;
rdfs:comment "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0008150 .
obo:WBPhenotype_0002250 a rdfs:Class ;
rdfs:label "silver hypersensitive" ;
rdfs:comment "Animals respond to silver at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000591 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001338 a rdfs:Class ;
rdfs:label "phentolamine resistant" ;
rdfs:comment "Animals fail to respond to the concentration of phentolamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001337 , obo:WBPhenotype_0001502 .
obo:GO_1903187 a rdfs:Class ;
rdfs:label "negative regulation of vitellogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1903186 .
obo:WBPhenotype_0000225 a rdfs:Class ;
rdfs:label "serotonin synthesis defective" ;
rdfs:comment "Animals are unable to carry out the chemical reactions and pathways resulting in the formation of serotonin." ;
rdfs:subClassOf obo:WBPhenotype_0000222 .
obo:GO_0032223 a rdfs:Class ;
rdfs:label "negative regulation of synaptic transmission, cholinergic" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ;
rdfs:subClassOf obo:GO_0032222 , obo:GO_0050805 , obo:GO_0065007 .
obo:WBPhenotype_0001363 a rdfs:Class ;
rdfs:label "head cavity" ;
rdfs:comment "The head contains cavities, possibly indicative of inappropriate cell death." ;
rdfs:subClassOf obo:WBPhenotype_0000071 .
obo:GO_0016817 a rdfs:Class ;
rdfs:label "hydrolase activity, acting on acid anhydrides" ;
rdfs:comment "Catalysis of the hydrolysis of any acid anhydride." ;
rdfs:subClassOf obo:GO_0016787 .
obo:CHEBI_17522 a rdfs:Class ;
rdfs:label "alditol" ;
rdfs:comment "A carbohydrate that is an acyclic polyol having the general formula HOCH2[CH(OH)]nCH2OH (formally derivable from an aldose by reduction of the carbonyl group)." ;
rdfs:subClassOf obo:CHEBI_16646 , obo:CHEBI_26191 .
obo:WBPhenotype_0000694 a rdfs:Class ;
rdfs:label "hermaphrodite sterile" ;
rdfs:comment "Hermaphrodites fail to generate viable self-progeny and/or cross-progeny." ;
rdfs:subClassOf obo:WBPhenotype_0000688 , obo:WBPhenotype_0001259 .
obo:WBbt_0008425 a rdfs:Class ;
rdfs:label "hook" ;
rdfs:comment "A small lump on the gubernaculum of the male tail. This structure lies on the ventral surface just anterior and central to the base of the spicule openings and contains a sensory structure called the hook sensillum." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:GO_0048608 a rdfs:Class ;
rdfs:label "reproductive structure development" ;
rdfs:comment "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0048856 .
obo:PATO_0002505 a rdfs:Class .
obo:GO_0010389 a rdfs:Class ;
rdfs:label "regulation of G2/M transition of mitotic cell cycle" ;
rdfs:comment "Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901990 , obo:GO_1902749 .
obo:GO_1904409 a rdfs:Class ;
rdfs:label "regulation of secretory granule organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of secretory granule organization." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:GO_0017157 a rdfs:Class ;
rdfs:label "regulation of exocytosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of exocytosis." ;
rdfs:subClassOf obo:GO_0060627 , obo:GO_0065007 , obo:GO_1903530 .
obo:WBPhenotype_0000344 a rdfs:Class ;
rdfs:label "cloacal structures protrude" ;
rdfs:comment "Any of the contents that comprise the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus extend into the external environment through the cloacal opening." ;
rdfs:subClassOf obo:WBPhenotype_0000908 .
obo:WBPhenotype_0000571 a rdfs:Class ;
rdfs:label "axon vesicle variant" ;
rdfs:comment "Axons of animals exhibit variations in the gross structure or organization of its spherical, membrane-bound, fluid-filled organelles, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000568 .
obo:WBbt_0004873 a rdfs:Class ;
rdfs:label "D" ;
rdfs:comment "Embryonic founder cell" ;
rdfs:subClassOf obo:WBbt_0008447 .
obo:WBPhenotype_0004013 a rdfs:Class ;
rdfs:label "sperm release defective" ;
rdfs:comment "Any variation in the initial movement of sperm through the vas deferens, exiting the cloaca, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000284 .
obo:WBPhenotype_0001799 a rdfs:Class ;
rdfs:label "inhibition of synaptogenesis hyperactive" ;
rdfs:comment "The processes that inhibit the location or frequency of formation of synapses are upregulated compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000944 .
obo:WBPhenotype_0002082 a rdfs:Class ;
rdfs:label "peptide uptake by intestinal cell decreased" ;
rdfs:comment "Animals exhibit a decrease in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002080 .
obo:CHEBI_38631 a rdfs:Class ;
rdfs:label "aminoalkylindole" ;
rdfs:subClassOf obo:CHEBI_24828 .
obo:WBPhenotype_0000790 a rdfs:Class ;
rdfs:label "fluoxetine resistant" ;
rdfs:comment "Animals fail to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 .
obo:WBPhenotype_0001540 a rdfs:Class ;
rdfs:label "dauer lifespan variant" ;
rdfs:comment "The life span of dauer-staged animals is either longer or shorter than that observed in control dauer animals." ;
rdfs:subClassOf obo:WBPhenotype_0000039 , obo:WBPhenotype_0001547 .
obo:WBPhenotype_0000254 a rdfs:Class ;
rdfs:label "chloride chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to chloride. In C. elegans, chloride is typically an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001439 , obo:WBPhenotype_0001458 .
obo:CHEBI_51958 a rdfs:Class ;
rdfs:label "organic polycyclic compound" ;
rdfs:subClassOf obo:CHEBI_33635 , obo:CHEBI_33832 .
obo:CHEBI_16583 a rdfs:Class ;
rdfs:label "butane-2,3-dione" ;
rdfs:comment "An α-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_51869 .
obo:GO_1905673 a rdfs:Class ;
rdfs:label "positive regulation of lysosome organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lysosome organization." ;
rdfs:subClassOf obo:GO_0044090 , obo:GO_0065007 , obo:GO_1905671 .
obo:PATO_0002255 a rdfs:Class ;
rdfs:label "grooved" ;
rdfs:comment "Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels." ;
rdfs:subClassOf obo:PATO_0000150 .
obo:CHEBI_77278 a rdfs:Class ;
rdfs:label "6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole" ;
rdfs:comment "An imidazothiazole that is imidazo[2,1-b][1,3]thiazole in which the double bonds at the 2-3 and 5-6 positions have been reduced to single bonds and in which one of the hydrogens at position 6 is replaced by a phenyl group." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_48909 .
obo:WBPhenotype_0001743 a rdfs:Class ;
rdfs:label "mitosis variant" ;
rdfs:comment "Any variation in the division of the eukaryotic cell nucleus to produce two daughter nuclei that contain the identical chromosome complement of their mother compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:GO_0001560 a rdfs:Class ;
rdfs:label "regulation of cell growth by extracellular stimulus" ;
rdfs:comment "Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time." ;
rdfs:subClassOf obo:GO_0001558 .
obo:WBPhenotype_0001822 a rdfs:Class ;
rdfs:label "dauer pheromone secretion variant" ;
rdfs:comment "Animals produce pheromone but it does not undergo controlled release into the environment." ;
rdfs:subClassOf obo:WBPhenotype_0000258 , obo:WBPhenotype_0000609 .
obo:WBPhenotype_0000567 a rdfs:Class ;
rdfs:label "dorsal coiler" ;
rdfs:comment "A coiling body that bends dorsally." ;
rdfs:subClassOf obo:WBPhenotype_0000565 .
obo:WBbt_0005779 a rdfs:Class ;
rdfs:label "striated muscle" ;
rdfs:comment "A multiple sarcomere muscle cell in which the thin and thick filaments adopt highly ordered patterns, with the thin filaments anchored at dense bodies." ;
rdfs:subClassOf obo:WBbt_0003675 .
obo:WBPhenotype_0001394 a rdfs:Class ;
rdfs:label "cell acidification defective" ;
rdfs:comment "Animals lack the capacity to reduce the internal pH of a cell." ;
rdfs:subClassOf obo:WBPhenotype_0001393 .
obo:GO_0070132 a rdfs:Class ;
rdfs:label "regulation of mitochondrial translational initiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0065007 , obo:GO_0070129 .
obo:GO_0035825 a rdfs:Class ;
rdfs:label "homologous recombination" ;
rdfs:comment "A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules." ;
rdfs:subClassOf obo:GO_0006310 .
obo:GO_0060099 a rdfs:Class ;
rdfs:label "regulation of phagocytosis, engulfment" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ;
rdfs:subClassOf obo:GO_0050764 , obo:GO_0065007 , obo:GO_1905153 .
obo:GO_0051179 a rdfs:Class ;
rdfs:label "localization" ;
rdfs:comment "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_0043232 a rdfs:Class ;
rdfs:label "intracellular membraneless organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." ;
rdfs:subClassOf obo:GO_0043228 , obo:GO_0043229 .
obo:GO_0051079 a rdfs:Class ;
rdfs:label "meiosis I nuclear membrane disassembly" ;
rdfs:comment "The controlled breakdown of the nuclear membranes during the first division of meiosis." ;
rdfs:subClassOf obo:GO_0051078 , obo:GO_0051081 .
obo:GO_0048232 a rdfs:Class ;
rdfs:label "male gamete generation" ;
rdfs:comment "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." ;
rdfs:subClassOf obo:GO_0007276 .
obo:GO_0006873 a rdfs:Class ;
rdfs:label "intracellular monoatomic ion homeostasis" ;
rdfs:comment "A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ;
rdfs:subClassOf obo:GO_0050801 , obo:GO_0055082 .
obo:WBPhenotype_0001927 a rdfs:Class ;
rdfs:label "extra distal tip cells" ;
rdfs:comment "Animals produce an excess number of distal tip cells compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001656 , obo:WBPhenotype_0002175 .
obo:CHEBI_25940 a rdfs:Class ;
rdfs:label "peroxides" ;
rdfs:comment "Compounds of structure ROOR'." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25741 .
obo:WBPhenotype_0001862 a rdfs:Class ;
rdfs:label "manganese homeostasis variant" ;
rdfs:comment "Variations in the regulation of levels, transport, and metabolism of manganese ions within an organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002029 .
obo:GO_0043143 a rdfs:Class ;
rdfs:label "regulation of translation by machinery localization" ;
rdfs:comment "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0008104 .
obo:PATO_0001236 a rdfs:Class ;
rdfs:label "process quality" ;
rdfs:comment "A quality which inheres in an process." ;
rdfs:subClassOf obo:PATO_0000001 .
obo:CHEBI_33861 a rdfs:Class ;
rdfs:label "transition element coordination entity" ;
rdfs:subClassOf obo:CHEBI_33240 , obo:CHEBI_33497 .
obo:GO_0031401 a rdfs:Class ;
rdfs:label "positive regulation of protein modification process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ;
rdfs:subClassOf obo:GO_0031399 , obo:GO_0051247 , obo:GO_0065007 .
obo:CHEBI_33855 a rdfs:Class ;
rdfs:label "arenecarbaldehyde" ;
rdfs:comment "Any aldehyde in which the carbonyl group is attached to an aromatic moiety." ;
rdfs:subClassOf obo:CHEBI_17478 , obo:CHEBI_33659 .
obo:WBPhenotype_0001052 a rdfs:Class ;
rdfs:label "anion positive chemotaxis variant" ;
rdfs:comment "Animals exhibit variations in the characteristic movement towards typically attractive anions compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001047 .
obo:WBPhenotype_0000120 a rdfs:Class ;
rdfs:label "protein expression reduced" ;
rdfs:comment "Any change that results in lower than normal levels of protein expression compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001400 .
obo:CHEBI_25699 a rdfs:Class ;
rdfs:label "organic ion" ;
rdfs:subClassOf obo:CHEBI_24870 , obo:CHEBI_50860 .
obo:WBPhenotype_0002078 a rdfs:Class ;
rdfs:label "histone methylation variant" ;
rdfs:comment "The pattern or state of methyl modifications of histone varies from that of controls." ;
rdfs:subClassOf obo:WBPhenotype_0001383 .
obo:CHEBI_46997 a rdfs:Class ;
rdfs:label "L-ribose" ;
rdfs:comment "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in L-glyceraldehyde." ;
rdfs:subClassOf obo:CHEBI_33942 .
obo:WBPhenotype_0001012 a rdfs:Class ;
rdfs:label "organism pathogen response variant" ;
rdfs:comment "Animals exhibit variations in their response to disease causing agents, compared to control. Pathogen response includes prevention, damage control and recovery from the infection caused by the attack." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBPhenotype_0001271 a rdfs:Class ;
rdfs:label "pathogen induced death increased" ;
rdfs:comment "Animals are more prone to lethality as a result of infection compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001013 .
obo:GO_1904171 a rdfs:Class ;
rdfs:label "negative regulation of bleb assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120033 , obo:GO_1904170 .
obo:GO_0050928 a rdfs:Class ;
rdfs:label "negative regulation of positive chemotaxis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." ;
rdfs:subClassOf obo:GO_0050922 , obo:GO_0050926 , obo:GO_0065007 .
obo:WBPhenotype_0002042 a rdfs:Class ;
rdfs:label "molting arrhythmic" ;
rdfs:comment "Molting cycles do not occur in a temporally controlled manner and cannot be synchronized across a population." ;
rdfs:subClassOf obo:WBPhenotype_0002041 .
obo:WBPhenotype_0001114 a rdfs:Class ;
rdfs:label "cell cycle defective early emb" ;
rdfs:comment "The progression of biochemical and morphological processes that occur during successive replication or nuclear replication events is disrupted during the early embryonic stage." ;
rdfs:subClassOf obo:WBPhenotype_0000740 , obo:WBPhenotype_0001100 .
obo:CHEBI_24473 a rdfs:Class ;
rdfs:label "halogen" ;
rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33560 .
obo:WBPhenotype_0000724 a rdfs:Class ;
rdfs:label "protein secretion variant" ;
rdfs:comment "Variations in the regulated release of proteins from a cell or group of cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000258 .
obo:CHEBI_25703 a rdfs:Class ;
rdfs:label "organic phosphate" ;
rdfs:subClassOf obo:CHEBI_25710 , obo:CHEBI_26020 .
obo:GO_0120025 a rdfs:Class ;
rdfs:label "plasma membrane bounded cell projection" ;
rdfs:comment "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." ;
rdfs:subClassOf obo:GO_0042995 .
obo:GO_0001966 a rdfs:Class ;
rdfs:label "thigmotaxis" ;
rdfs:comment "The directed movement of an organism along a spatial gradient of mechanical contact with solid surfaces, typically manifested as a preference for maintaining proximity to walls, edges, or boundaries." ;
rdfs:subClassOf obo:GO_0007610 .
obo:PATO_0002006 a rdfs:Class ;
rdfs:label "2-D shape" ;
rdfs:comment "A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:WBPhenotype_0000113 a rdfs:Class ;
rdfs:label "RNA expression variant" ;
rdfs:comment "Variations in the biogenesis and stability of any class of RNA molecules (rRNAs, miRNAs, tRNAs etc) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:WBbt_0004942 a rdfs:Class ;
rdfs:label "U cell" ;
rdfs:comment "Rectal cell, postembryonic blast cell in male" ;
rdfs:subClassOf obo:WBbt_0006783 , obo:WBbt_0008182 .
obo:WBPhenotype_0002304 a rdfs:Class ;
rdfs:label "head movement decreased" ;
rdfs:comment "Animals exhibit a decrease in the movement of the most anterior portion of the body to a new location compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000595 , obo:WBPhenotype_0001265 .
obo:GO_0031122 a rdfs:Class ;
rdfs:label "cytoplasmic microtubule organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." ;
rdfs:subClassOf obo:GO_0000226 , obo:GO_0097435 .
obo:WBPhenotype_0001703 a rdfs:Class ;
rdfs:label "body bend variant" ;
rdfs:comment "Any variation in the maximum ventral and dorsal flex of the animal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0004018 .
obo:CHEBI_35341 a rdfs:Class ;
rdfs:label "steroid" ;
rdfs:comment "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." ;
rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_51958 .
obo:GO_0050839 a rdfs:Class ;
rdfs:label "cell adhesion molecule binding" ;
rdfs:comment "Binding to a cell adhesion molecule." ;
rdfs:subClassOf obo:GO_0005515 .
obo:CHEBI_32450 a rdfs:Class ;
rdfs:label "D-cysteinate(2-)" ;
rdfs:comment "The D-enantiomer of cysteinate(2−)." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_32457 .
obo:WBPhenotype_0001800 a rdfs:Class ;
rdfs:label "pathogen induced antimicrobial gene expression variant" ;
rdfs:comment "Changes in the levels of innate immune gene products in response to pathogen exposure are significantly different from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001857 , obo:WBPhenotype_0002164 , obo:WBPhenotype_0002534 .
obo:GO_0007017 a rdfs:Class ;
rdfs:label "microtubule-based process" ;
rdfs:comment "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0000560 a rdfs:Class ;
rdfs:label "calcium channel modulator resistant" ;
rdfs:comment "Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0000558 .
obo:GO_0032594 a rdfs:Class ;
rdfs:label "protein transport within lipid bilayer" ;
rdfs:comment "The directed movement of a protein from one location to another within a lipid bilayer." ;
rdfs:subClassOf obo:GO_0006886 , obo:GO_0015031 , obo:GO_0061024 .
obo:WBPhenotype_0000409 a rdfs:Class ;
rdfs:label "organism morphology variable" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any of its parts at different stages of the lifecycle, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000535 .
obo:WBPhenotype_0000131 a rdfs:Class ;
rdfs:label "pheromone induced dauer formation defective" ;
rdfs:comment "Animals do not enter dauer when exposed to chemicals that induce dauer formation in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000013 , obo:WBPhenotype_0000132 .
obo:GO_1905638 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial mRNA catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process." ;
rdfs:subClassOf obo:GO_0000961 , obo:GO_0065007 , obo:GO_1902373 , obo:GO_1905637 .
obo:WBPhenotype_0001103 a rdfs:Class ;
rdfs:label "spindle absent early emb" ;
rdfs:comment "Early embryos lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ;
rdfs:subClassOf obo:WBPhenotype_0001102 , obo:WBPhenotype_0002418 .
obo:GO_0046903 a rdfs:Class ;
rdfs:label "secretion" ;
rdfs:comment "The controlled release of a substance by a cell or a tissue." ;
rdfs:subClassOf obo:GO_0006810 .
obo:WBPhenotype_0000913 a rdfs:Class ;
rdfs:label "basal lamina morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the basal lamina compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000600 , obo:WBPhenotype_0001523 .
obo:WBPhenotype_0000853 a rdfs:Class ;
rdfs:label "intraflagellar transport variant" ;
rdfs:comment "Variations in the bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000851 .
obo:WBPhenotype_0002667 a rdfs:Class ;
rdfs:label "sodium iodide resistant"@en ;
rdfs:comment "Animals fail to respond to the concentration of sodium iodide that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 .
obo:GO_2001230 a rdfs:Class ;
rdfs:label "positive regulation of response to gamma radiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of response to gamma radiation." ;
rdfs:subClassOf obo:GO_0048584 , obo:GO_0065007 , obo:GO_2001228 .
obo:WBPhenotype_0002385 a rdfs:Class ;
rdfs:label "high pH avoidance defective" ;
rdfs:comment "Animals fail to avoid a high pH (alkaline) environment as compared to control animals. This is at very high pH, for example around pH11." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:WBPhenotype_0000449 a rdfs:Class ;
rdfs:label "second adult cuticle" ;
rdfs:comment "A duplication of the developmental program that forms the adult-type rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells." ;
rdfs:subClassOf obo:WBPhenotype_0000448 .
obo:PATO_0000498 a rdfs:Class ;
rdfs:label "increased duration" ;
rdfs:comment "A duration quality of a process which is relatively high." ;
rdfs:subClassOf obo:PATO_0001309 , obo:PATO_0002304 .
obo:WBPhenotype_0001203 a rdfs:Class ;
rdfs:label "nicotine resistant" ;
rdfs:comment "Animals fail to respond to the concentration of nicotine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001573 , obo:WBPhenotype_0001578 .
obo:CHEBI_67142 a rdfs:Class ;
rdfs:label "nucleobase analogue" ;
rdfs:comment "A molecule that can substitute for a normal nucleobase in nucleic acids." ;
rdfs:subClassOf obo:CHEBI_33832 .
obo:WBPhenotype_0001758 a rdfs:Class ;
rdfs:label "neuropeptide processing variant" ;
rdfs:comment "Variations in the chemical reactions and pathways involved in the formation and maturation of specialized peptidergic neurotransmitters encoded as preproproteins that are posttranslationally processed to yield bioactive neuropeptides compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000122 , obo:WBPhenotype_0001757 .
obo:CHEBI_74783 a rdfs:Class ;
rdfs:label "astringent" ;
rdfs:comment "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:WBPhenotype_0002618 a rdfs:Class ;
rdfs:label "cytosolic calcium levels decreased"@en ;
rdfs:comment "Cells exhibit a lower level of calcium in the cytosol, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002616 .
obo:GO_1904145 a rdfs:Class ;
rdfs:label "negative regulation of meiotic cell cycle process involved in oocyte maturation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0051447 , obo:GO_0065007 , obo:GO_1900194 , obo:GO_1903538 .
obo:WBls_0000019 a rdfs:Class ;
rdfs:label "2-fold embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000807 .
obo:CHEBI_26873 a rdfs:Class ;
rdfs:label "terpenoid" ;
rdfs:comment "Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group." ;
rdfs:subClassOf obo:CHEBI_24913 .
obo:WBPhenotype_0001282 a rdfs:Class ;
rdfs:label "mitochondrial metabolism variant" ;
rdfs:comment "Variations in the chemical reactions and pathways of the mitochondria compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001283 .
obo:WBPhenotype_0000009 a rdfs:Class ;
rdfs:label "anesthetic resistant" ;
rdfs:comment "Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0000627 .
obo:CHEBI_33282 a rdfs:Class ;
rdfs:label "antibacterial agent" ;
rdfs:comment "A substance (or active part thereof) that kills or slows the growth of bacteria." ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:WBPhenotype_0000730 a rdfs:Class ;
rdfs:label "apoptosis variant" ;
rdfs:comment "Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell." ;
rdfs:subClassOf obo:WBPhenotype_0001172 .
obo:CHEBI_38092 a rdfs:Class ;
rdfs:label "cardenolide glycoside" ;
rdfs:comment "Any member of the class of cardenolides with glycosyl residues attached to position 3." ;
rdfs:subClassOf obo:CHEBI_74634 , obo:CHEBI_83970 .
obo:WBPhenotype_0000285 a rdfs:Class ;
rdfs:label "ray tips swollen" ;
rdfs:comment "The extreme ends of any of the finger-like sensory sensilla that project from the tail and embed in the male fan appear bloated or distended." ;
rdfs:subClassOf obo:WBPhenotype_0000505 .
obo:CHEBI_82744 a rdfs:Class ;
rdfs:label "aliphatic aldoxime" ;
rdfs:comment "Any aldoxime derived from an aliphatic aldehyde." ;
rdfs:subClassOf obo:CHEBI_22307 .
obo:WBPhenotype_0002435 a rdfs:Class ;
rdfs:label "less susceptibility to induced DNA damage" ;
rdfs:comment "Nematodes exposed to DNA damaging agents or conditions exhibit lower susceptibility to DNA damage than other animals." ;
rdfs:subClassOf obo:WBPhenotype_0000739 .
obo:WBbt_0004015 a rdfs:Class ;
rdfs:label "AB" ;
rdfs:comment "Embryonic founder cell" ;
rdfs:subClassOf obo:WBbt_0008447 .
obo:WBPhenotype_0002255 a rdfs:Class ;
rdfs:label "amino acid metabolism variant" ;
rdfs:comment "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of amino acids within the organism or cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000463 .
obo:CHEBI_37886 a rdfs:Class ;
rdfs:label "adrenergic agonist" ;
rdfs:comment "An agent that selectively binds to and activates adrenergic receptors." ;
rdfs:subClassOf obo:CHEBI_37962 .
obo:GO_0080134 a rdfs:Class ;
rdfs:label "regulation of response to stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 .
obo:WBPhenotype_0002313 a rdfs:Class ;
rdfs:label "turning frequency increased" ;
rdfs:comment "Animals exhibit an increase in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." ;
rdfs:subClassOf obo:WBPhenotype_0002312 .
obo:GO_0001707 a rdfs:Class ;
rdfs:label "mesoderm formation" ;
rdfs:comment "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0001704 .
obo:CHEBI_24384 a rdfs:Class ;
rdfs:label "glycogens" ;
rdfs:subClassOf obo:CHEBI_37163 .
obo:WBPhenotype_0000729 a rdfs:Class ;
rdfs:label "cell death variant" ;
rdfs:comment "Animals exhibit variations in any of the processes that lead to the termination of vital functions of a cell." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0002485 a rdfs:Class ;
rdfs:label "germline precursor cell morphology variant"@en ;
rdfs:comment "Any variation in the morphological appearance of germline precursor cells compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002108 .
obo:WBPhenotype_0000752 a rdfs:Class ;
rdfs:label "L2 larval development variant" ;
rdfs:comment "Variations in the progression of the second larval stage compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000750 .
obo:CHEBI_27175 a rdfs:Class ;
rdfs:label "tyramines" ;
rdfs:comment "Aralkylamino compounds which contain a tyramine skeleton." ;
rdfs:subClassOf obo:CHEBI_33853 , obo:CHEBI_64365 .
obo:CHEBI_38627 a rdfs:Class ;
rdfs:label "diazine" ;
rdfs:comment "The parent structure of the diazines." ;
rdfs:subClassOf obo:CHEBI_35555 , obo:CHEBI_38179 , obo:CHEBI_38313 , obo:CHEBI_50893 .
obo:WBPhenotype_0001122 a rdfs:Class ;
rdfs:label "reversed asynchrony early emb" ;
rdfs:comment "P1 divides before AB." ;
rdfs:subClassOf obo:WBPhenotype_0001120 .
obo:WBPhenotype_0001080 a rdfs:Class ;
rdfs:label "excessive blebbing early emb" ;
rdfs:comment "Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos." ;
rdfs:subClassOf obo:WBPhenotype_0001079 .
obo:GO_0034655 a rdfs:Class ;
rdfs:label "nucleobase-containing compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0006139 , obo:GO_0009056 .
obo:WBPhenotype_0000890 a rdfs:Class ;
rdfs:label "larval pigmentation variant" ;
rdfs:comment "Larva exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001009 .
obo:GO_0042770 a rdfs:Class ;
rdfs:label "signal transduction in response to DNA damage" ;
rdfs:comment "A cascade of processes induced by the detection of DNA damage within a cell." ;
rdfs:subClassOf obo:GO_0006974 , obo:GO_0035556 .
obo:WBPhenotype_0001212 a rdfs:Class ;
rdfs:label "cuticle fragile" ;
rdfs:comment "The strength of the cuticle is less robust than that observed for control animals. In C. elegans the strength of the cuticle is often assayed by it's ability to protect the animal from exposure to bleach or other compounds." ;
rdfs:subClassOf obo:WBPhenotype_0002640 .
obo:GO_1901700 a rdfs:Class ;
rdfs:label "response to oxygen-containing compound" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." ;
rdfs:subClassOf obo:GO_0042221 .
obo:WBPhenotype_0000965 a rdfs:Class ;
rdfs:label "somatic cell death variant" ;
rdfs:comment "Animals exhibit variations in the programmed cell death pathway that is triggered in cells other than germ cells and that is not subject to upstream checkpoint regulation." ;
rdfs:subClassOf obo:WBPhenotype_0001172 .
obo:GO_0042325 a rdfs:Class ;
rdfs:label "regulation of phosphorylation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." ;
rdfs:subClassOf obo:GO_0051174 , obo:GO_0065007 .
obo:WBPhenotype_0002321 a rdfs:Class ;
rdfs:label "forward point velocity decreased" ;
rdfs:comment "Animals exhibit decreased velocity of forward translocation of any point along the animal's track from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001716 .
obo:CHEBI_36309 a rdfs:Class ;
rdfs:label "cyclic tetrapyrrole" ;
rdfs:subClassOf obo:CHEBI_26932 , obo:CHEBI_47882 .
obo:WBPhenotype_0000848 a rdfs:Class ;
rdfs:label "developmental delay" ;
rdfs:comment "The developmental progression of an animal over time, from its formation to its mature structure is delayed compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000438 .
obo:CHEBI_38958 a rdfs:Class ;
rdfs:label "indole alkaloid" ;
rdfs:comment "An alkaloid containing an indole skeleton." ;
rdfs:subClassOf obo:CHEBI_22315 .
obo:WBPhenotype_0002202 a rdfs:Class ;
rdfs:label "pharynx extension defective" ;
rdfs:comment "Embryos exhibit defects in the extension of pharyngeal cells toward the buccal opening during embryogenesis compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001748 .
obo:GO_0071026 a rdfs:Class ;
rdfs:label "cytoplasmic RNA surveillance" ;
rdfs:comment "The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm." ;
rdfs:subClassOf obo:GO_0071025 .
obo:GO_0032781 a rdfs:Class ;
rdfs:label "positive regulation of ATP-dependent activity" ;
rdfs:comment "Any process that activates or increases the rate of an ATP-dependent activity." ;
rdfs:subClassOf obo:GO_0043462 , obo:GO_0044093 , obo:GO_0065007 .
obo:GO_0051307 a rdfs:Class ;
rdfs:label "meiotic chromosome separation" ;
rdfs:comment "The process in which chromosomes are physically detached from each other during meiosis." ;
rdfs:subClassOf obo:GO_0051304 , obo:GO_1903046 .
obo:GO_0008630 a rdfs:Class ;
rdfs:label "intrinsic apoptotic signaling pathway in response to DNA damage" ;
rdfs:comment "The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered." ;
rdfs:subClassOf obo:GO_0006974 , obo:GO_0097193 .
obo:GO_0070133 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial translational initiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." ;
rdfs:subClassOf obo:GO_0045947 , obo:GO_0065007 , obo:GO_0070132 .
obo:WBPhenotype_0001608 a rdfs:Class ;
rdfs:label "enflurane hypersensitive" ;
rdfs:comment "Animals respond to the anesthetic enflurane at lower concentrations or shorter exposure times than control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000008 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000779 a rdfs:Class ;
rdfs:label "late embryonic arrest" ;
rdfs:comment "Cessation of development during the final stages of embryogenesis. In C. elegans, this stage normally occurs 620-800 min after the first cleavage at 20C and is the stage after elongation." ;
rdfs:subClassOf obo:WBPhenotype_0000867 .
obo:WBPhenotype_0001253 a rdfs:Class ;
rdfs:label "wing cilia axoneme short" ;
rdfs:comment "The microtuble-based fibrillar-bundle, axoneme, of the wing cell cilia are reduced in length and do not extend into the sheath cell as far as they do in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001252 .
obo:GO_0071944 a rdfs:Class ;
rdfs:label "cell periphery" ;
rdfs:comment "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0008354 a rdfs:Class ;
rdfs:label "germ cell migration" ;
rdfs:comment "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." ;
rdfs:subClassOf obo:GO_0016477 .
obo:WBPhenotype_0000664 a rdfs:Class ;
rdfs:label "exaggerated body bends" ;
rdfs:comment "The maximum ventral and dorsal flex of the animal is greater than that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001703 .
obo:GO_0047496 a rdfs:Class ;
rdfs:label "vesicle transport along microtubule" ;
rdfs:comment "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." ;
rdfs:subClassOf obo:GO_0072384 , obo:GO_0099518 .
obo:GO_0035176 a rdfs:Class ;
rdfs:label "social behavior" ;
rdfs:comment "Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group." ;
rdfs:subClassOf obo:GO_0007610 , obo:GO_0051703 .
obo:WBPhenotype_0002450 a rdfs:Class ;
rdfs:label "burst pharyngeal pumping response to light" ;
rdfs:comment "Animals exhibit variations in the burst pharyngeal pumping response to light, during which the pharyngeal pumping rate slightly increases during the5-10 seconds after light exposure onset, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002446 .
obo:GO_0008104 a rdfs:Class ;
rdfs:label "intracellular protein localization" ;
rdfs:comment "Any process in which a protein is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0033036 .
obo:WBPhenotype_0002085 a rdfs:Class ;
rdfs:label "crossover formation variant" ;
rdfs:comment "The number of crossover events differs from that of observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002083 .
obo:CHEBI_33437 a rdfs:Class ;
rdfs:label "chlorine oxoanion" ;
rdfs:subClassOf obo:CHEBI_23117 , obo:CHEBI_33443 .
obo:GO_0090231 a rdfs:Class ;
rdfs:label "regulation of spindle checkpoint" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901976 .
obo:GO_0030312 a rdfs:Class ;
rdfs:label "external encapsulating structure" ;
rdfs:comment "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0001270 a rdfs:Class ;
rdfs:label "pathogen induced cell death reduced" ;
rdfs:comment "Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001269 .
obo:CHEBI_50902 a rdfs:Class ;
rdfs:label "genotoxin" ;
rdfs:comment "A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:WBPhenotype_0000589 a rdfs:Class ;
rdfs:label "obsolete no hermaphrodite variantity scored" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0001039 a rdfs:Class ;
rdfs:label "embryonic growth variant" ;
rdfs:comment "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the embryonic stage compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001015 .
obo:CHEBI_15854 a rdfs:Class ;
rdfs:label "quinine" ;
rdfs:comment "A cinchona alkaloid that is cinchonidine in which the hydrogen at the 6-position of the quinoline ring is substituted by methoxy." ;
rdfs:subClassOf obo:CHEBI_51323 .
obo:CHEBI_88230 a rdfs:Class ;
rdfs:label "autophagy inhibitor" ;
rdfs:comment "Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell)." ;
rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 .
obo:WBPhenotype_0002465 a rdfs:Class ;
rdfs:label "histone ubiquitination variant" ;
rdfs:comment "The pattern or state of ubiquitin modifications of histones varies from that of controls." ;
rdfs:subClassOf obo:WBPhenotype_0001865 .
obo:CHEBI_33485 a rdfs:Class ;
rdfs:label "chalcogen oxoanion" ;
rdfs:subClassOf obo:CHEBI_35406 .
obo:CHEBI_25805 a rdfs:Class ;
rdfs:label "oxygen atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25585 , obo:CHEBI_33303 .
obo:WBPhenotype_0002326 a rdfs:Class ;
rdfs:label "velocity of movement decreased" ;
rdfs:comment "Animals exhibit a decrease in the net velocity of an animal." ;
rdfs:subClassOf obo:WBPhenotype_0004025 .
obo:WBPhenotype_0001293 a rdfs:Class ;
rdfs:label "larval physiology phenotype" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the larva to carry out its normal metabolic functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000576 , obo:WBPhenotype_0002555 .
obo:WBPhenotype_0001569 a rdfs:Class ;
rdfs:label "body wall muscle myosin organization defective" ;
rdfs:comment "The characteristic organization of myosin filaments into discrete A-bands within the muscle cells is disrupted. In C. elegans, myosin filaments no longer appear as continuous longitudinally oriented fibers across the muscle quadrants." ;
rdfs:subClassOf obo:WBPhenotype_0000782 .
obo:WBPhenotype_0000264 a rdfs:Class ;
rdfs:label "cAMP chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to cAMP as defined by control animals. In C. elegans, cAMP is typically an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001441 , obo:WBPhenotype_0001463 .
obo:WBPhenotype_0002020 a rdfs:Class ;
rdfs:label "transmission of nerve impulse variant" ;
rdfs:comment "Transmission of the signal along the neuron varies from control. This process includes the flow of information from the neuron cell body to the synapse and across to the postsynaptic cell." ;
rdfs:subClassOf obo:WBPhenotype_0000612 .
obo:GO_0046827 a rdfs:Class ;
rdfs:label "positive regulation of protein export from nucleus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0046824 , obo:GO_0046825 , obo:GO_0065007 , obo:GO_0090316 .
obo:WBPhenotype_0000741 a rdfs:Class ;
rdfs:label "DNA damage checkpoint variant" ;
rdfs:comment "Mitotic cells exhibit variations in the execution of cell-cycle arrest in response to DNA damage." ;
rdfs:subClassOf obo:WBPhenotype_0000142 , obo:WBPhenotype_0000740 .
obo:GO_0007281 a rdfs:Class ;
rdfs:label "germ cell development" ;
rdfs:comment "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0022412 , obo:GO_0048468 .
obo:WBls_0000815 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during enclosing embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the enclosing embryo life stage" ;
rdfs:subClassOf obo:WBls_0000812 .
obo:CHEBI_27594 a rdfs:Class ;
rdfs:label "carbon atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25585 , obo:CHEBI_33306 .
obo:PATO_0002005 a rdfs:Class ;
rdfs:label "concavity" ;
rdfs:comment "Surface shape that refers to the inward or outward curvature of the surface." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:GO_0051402 a rdfs:Class ;
rdfs:label "neuron apoptotic process" ;
rdfs:comment "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." ;
rdfs:subClassOf obo:GO_0006915 .
obo:CHEBI_3992 a rdfs:Class ;
rdfs:label "cyclic ketone" ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:WBPhenotype_0002207 a rdfs:Class ;
rdfs:label "missing gonad arms" ;
rdfs:comment "Animals are missing one or both gonad arms, the normally U-shaped projections of the gonad that extend into the anterior or posterior of the animal and bends back towards the center of the animal." ;
rdfs:subClassOf obo:WBPhenotype_0000399 .
obo:WBPhenotype_0001353 a rdfs:Class ;
rdfs:label "centration defective early emb" ;
rdfs:comment "The coordinated movement during prophase of the two centrosomes and the two pronuclei towards the center of the one cell embryo is abolished." ;
rdfs:subClassOf obo:WBPhenotype_0001152 .
obo:WBPhenotype_0001801 a rdfs:Class ;
rdfs:label "axodendritic polarity variant" ;
rdfs:comment "Animals fail to establish or maintain characteristics that delineate the dendrite from the axon. The exclusion of presynaptic components from the dendrite is one indication of axodendritic polarity." ;
rdfs:subClassOf obo:WBPhenotype_0000944 .
obo:WBPhenotype_0000746 a rdfs:Class ;
rdfs:label "cell division variant" ;
rdfs:comment "Any variation that alters the physical partitioning and separation of a cell into daughter cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0001214 a rdfs:Class ;
rdfs:label "obsolete metaphase to anaphase transition fails" ;
rdfs:comment "OBSOLETE." .
obo:PATO_0000140 a rdfs:Class ;
rdfs:label "position" ;
rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:GO_1903181 a rdfs:Class ;
rdfs:label "positive regulation of dopamine biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0045964 , obo:GO_0065007 , obo:GO_1903179 .
obo:PATO_0001362 a rdfs:Class ;
rdfs:label "fragile" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer's disposition to being easily damaged or destroyed." ;
rdfs:subClassOf obo:PATO_0001662 .
obo:CHEBI_35842 a rdfs:Class ;
rdfs:label "antirheumatic drug" ;
rdfs:comment "A drug used to treat rheumatoid arthritis." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:PATO_0001290 a rdfs:Class ;
rdfs:label "fluorescent" ;
rdfs:comment "A fluorescence quality inhering in a bearer by virtue of emitting light during exposure to radiation from an external source." ;
rdfs:subClassOf obo:PATO_0000018 .
obo:GO_1905864 a rdfs:Class ;
rdfs:label "regulation of Atg1/ULK1 kinase complex assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0065007 .
obo:WBPhenotype_0000593 a rdfs:Class ;
rdfs:label "copper hypersensitive" ;
rdfs:comment "Animals respond to copper at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000592 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001855 a rdfs:Class ;
rdfs:label "fluoride resistant" ;
rdfs:comment "Animals fail to respond to the concentration of fluoride ions that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to fluoride ions to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 .
obo:WBbt_0005312 a rdfs:Class ;
rdfs:label "copulatory spicule" ;
rdfs:subClassOf obo:WBbt_0005757 .
obo:WBPhenotype_0001630 a rdfs:Class ;
rdfs:label "gut obstructed" ;
rdfs:comment "Any variation in the developmental progression of the intestine that leads to a blockage in the alimentary canal." ;
rdfs:subClassOf obo:WBPhenotype_0000708 , obo:WBPhenotype_0000710 .
obo:GO_0051258 a rdfs:Class ;
rdfs:label "protein polymerization" ;
rdfs:comment "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." ;
rdfs:subClassOf obo:GO_0065003 .
obo:GO_0001101 a rdfs:Class ;
rdfs:label "response to acid chemical" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." ;
rdfs:subClassOf obo:GO_0042221 .
obo:CHEBI_39123 a rdfs:Class ;
rdfs:label "calcium cation" ;
rdfs:subClassOf obo:CHEBI_33513 , obo:CHEBI_39124 .
obo:CHEBI_83039 a rdfs:Class ;
rdfs:label "crustacean metabolite" ;
rdfs:comment "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." ;
rdfs:subClassOf obo:CHEBI_75767 .
obo:GO_0099512 a rdfs:Class ;
rdfs:label "supramolecular fiber" ;
rdfs:comment "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." ;
rdfs:subClassOf obo:GO_0099081 .
obo:GO_0016239 a rdfs:Class ;
rdfs:label "positive regulation of macroautophagy" ;
rdfs:comment "Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation." ;
rdfs:subClassOf obo:GO_0010508 , obo:GO_0016241 , obo:GO_0065007 .
obo:WBPhenotype_0002315 a rdfs:Class ;
rdfs:label "roaming variant" ;
rdfs:comment "Animals exhibit variations in their movement at high-speed in the forward direction with brief backward movement compared to control. During roaming, control animals often traverse wide regions." ;
rdfs:subClassOf obo:WBPhenotype_0000641 , obo:WBPhenotype_0000662 .
obo:CHEBI_17120 a rdfs:Class ;
rdfs:label "hexanoate" ;
rdfs:comment "A short-chain fatty acid anion that is the conjugate base of hexanoic acid (also known as caproic acid)." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_58951 , obo:CHEBI_58954 , obo:CHEBI_78116 .
obo:WBPhenotype_0000807 a rdfs:Class ;
rdfs:label "G lineages variant" ;
rdfs:comment "The descendants of the G1 or G2 exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000825 .
obo:WBPhenotype_0000271 a rdfs:Class ;
rdfs:label "obsolete cell cycle slow" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000864 a rdfs:Class ;
rdfs:label "early elongation arrest" ;
rdfs:comment "Cessation of development during the initial period of elongation. In C. elegans, this period refers to the conversion of the bean-shaped embryo into the two-fold- shaped embryo." ;
rdfs:subClassOf obo:WBPhenotype_0000867 .
obo:CHEBI_16385 a rdfs:Class ;
rdfs:label "organic sulfide" ;
rdfs:comment "Compounds having the structure RSR (R ≠ H). Such compounds were once called thioethers." ;
rdfs:subClassOf obo:CHEBI_26822 , obo:CHEBI_33261 .
obo:WBPhenotype_0002234 a rdfs:Class ;
rdfs:label "increased acidified compartments" ;
rdfs:comment "Animals contain excess acidified intracellular compartments. These compartments are positive for indicators such as Acridine Orange as well as LysoTracker Red, in a lysosome-like manner." ;
rdfs:subClassOf obo:WBPhenotype_0001393 .
obo:WBPhenotype_0002096 a rdfs:Class ;
rdfs:label "golgi apparatus morphology variant" ;
rdfs:comment "Any variation in the form or composition of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002089 .
obo:WBPhenotype_0000833 a rdfs:Class ;
rdfs:label "U lineage variant" ;
rdfs:comment "The descendants of the U cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000809 .
obo:GO_2000302 a rdfs:Class ;
rdfs:label "positive regulation of synaptic vesicle exocytosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis." ;
rdfs:subClassOf obo:GO_0001956 , obo:GO_0065007 , obo:GO_1903307 , obo:GO_2000300 .
obo:WBPhenotype_0001225 a rdfs:Class ;
rdfs:label "phasmid socket absent" ;
rdfs:comment "Animals are missing the interfacial hypodermal cell (socket cell) of the phasmid sensillum pore." ;
rdfs:subClassOf obo:WBPhenotype_0001527 , obo:WBPhenotype_0002552 .
obo:CHEBI_16765 a rdfs:Class ;
rdfs:label "tryptamine" ;
rdfs:comment "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." ;
rdfs:subClassOf obo:CHEBI_27162 , obo:CHEBI_38631 , obo:CHEBI_38958 , obo:CHEBI_64365 .
obo:WBbt_0005757 a rdfs:Class ;
rdfs:label "male-specific anatomical entity" ;
rdfs:comment "cells or anatomical parts specific to the male sex" ;
rdfs:subClassOf obo:WBbt_0005752 .
obo:CHEBI_27882 a rdfs:Class ;
rdfs:label "(S)-colchicine" ;
rdfs:comment "A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions." ;
rdfs:subClassOf obo:CHEBI_23359 .
obo:WBPhenotype_0002457 a rdfs:Class ;
rdfs:label "ectopic vulva in male" ;
rdfs:comment "Formation in the male of the egg-laying organ of female and hermaphrodite nematodes. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ;
rdfs:subClassOf obo:WBPhenotype_0002499 .
obo:WBPhenotype_0001655 a rdfs:Class ;
rdfs:label "cadmium hypersensitive" ;
rdfs:comment "Animals respond to cadmium at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001653 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000106 a rdfs:Class ;
rdfs:label "inhibition of oocyte maturation variant" ;
rdfs:comment "Variations in the processes that negatively regulate the meiotic progression of oocytes (exit from diakinesis) in the absence of a signal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000105 .
obo:WBPhenotype_0002496 a rdfs:Class ;
rdfs:label "ectopic neuron"@en ;
rdfs:comment "Animals exhibit one or more neurons in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0001310 , obo:WBPhenotype_0002493 .
obo:GO_0070887 a rdfs:Class ;
rdfs:label "cellular response to chemical stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ;
rdfs:subClassOf obo:GO_0042221 , obo:GO_0051716 .
obo:WBPhenotype_0002290 a rdfs:Class ;
rdfs:label "tail bend angle decreased" ;
rdfs:comment "Animals exhibit a decrease in the extent of the maximum flex of the most posterior portion of the animal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002288 .
obo:CHEBI_136889 a rdfs:Class ;
rdfs:label "5beta steroid" ;
rdfs:comment "Any steroid that has β-configuration at position 5." ;
rdfs:subClassOf obo:CHEBI_35341 .
obo:CHEBI_27162 a rdfs:Class ;
rdfs:label "tryptamines" ;
rdfs:comment "Tryptamine and its substitution derivatives." ;
rdfs:subClassOf obo:CHEBI_24828 .
obo:WBPhenotype_0001181 a rdfs:Class ;
rdfs:label "accumulated somatic cell corpses" ;
rdfs:comment "Animals exhibit an increase in the quantity of non-germ line cells that have undergone programmed cell death but have not been engulfed." ;
rdfs:subClassOf obo:WBPhenotype_0000241 .
obo:CHEBI_64709 a rdfs:Class ;
rdfs:label "organic acid" ;
rdfs:comment "Any organic molecular entity that is acidic and contains carbon in covalent linkage." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:WBPhenotype_0002674 a rdfs:Class ;
rdfs:label "chil gene expression induction lacking infection"@en ;
rdfs:comment "Animals exhibit, in the absence of infection, induction of chil (chitinase-like) genes (e.g. chil-27), known immune response effectors in response to oomycete infection." ;
rdfs:subClassOf obo:WBPhenotype_0002539 .
obo:GO_0060279 a rdfs:Class ;
rdfs:label "positive regulation of ovulation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." ;
rdfs:subClassOf obo:GO_0051240 , obo:GO_0060278 , obo:GO_0065007 , obo:GO_2000243 .
obo:WBPhenotype_0000912 a rdfs:Class ;
rdfs:label "pericellular component morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of pericellular components compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000520 .
obo:GO_0043243 a rdfs:Class ;
rdfs:label "positive regulation of protein-containing complex disassembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ;
rdfs:subClassOf obo:GO_0043244 , obo:GO_0051130 , obo:GO_0065007 .
obo:CHEBI_24836 a rdfs:Class ;
rdfs:label "inorganic oxide" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_25741 .
obo:WBPhenotype_0001624 a rdfs:Class ;
rdfs:label "male tail curling serotonin resistant" ;
rdfs:comment "Animals fail to respond to the concentration of serotonin that elicits a male tail curling response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body." ;
rdfs:subClassOf obo:WBPhenotype_0000024 , obo:WBPhenotype_0001623 .
obo:WBPhenotype_0002240 a rdfs:Class ;
rdfs:label "gut granule morphology variant" ;
rdfs:comment "Any variation in the morphology of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000902 , obo:WBPhenotype_0001323 .
obo:WBPhenotype_0001281 a rdfs:Class ;
rdfs:label "stuffed pharynx" ;
rdfs:comment "Pharynx becomes clogged with food. In C. elegans, this is often a result of pharyngeal pumping defects." ;
rdfs:subClassOf obo:WBPhenotype_0000634 , obo:WBPhenotype_0000778 .
obo:WBPhenotype_0000509 a rdfs:Class ;
rdfs:label "sperm pseudopod variant" ;
rdfs:comment "Variation in the morphological appearance or composition of the pseudopod, a cellular projection that facilitates motility of the spermatozoa." ;
rdfs:subClassOf obo:WBPhenotype_0000388 .
obo:WBPhenotype_0001590 a rdfs:Class ;
rdfs:label "microtubule depolymerization variant" ;
rdfs:comment "Any variation that alters the characteristic removal of tubulin heterodimers from one or both ends of a microtubule compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001588 .
obo:WBPhenotype_0001482 a rdfs:Class ;
rdfs:label "frequency body bend reduced" ;
rdfs:comment "Animals exhibit a reduction in the frequency of oscillations between adjacent body segments from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001213 , obo:WBPhenotype_0004023 .
obo:WBPhenotype_0002544 a rdfs:Class ;
rdfs:label "hypersensitive to Enterobacter commensals"@en ;
rdfs:comment "Normally beneficial (or otherwise harmless, non-pathogenic) commensal Enterobacter bacteria, for example Enterobacter cloacae, become pathogenic to animals, unlike in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002356 .
obo:WBbt_0005375 a rdfs:Class ;
rdfs:label "anterior ganglion" ;
rdfs:comment "ganglion anterior to the nerve ring" ;
rdfs:subClassOf obo:WBbt_0005135 .
obo:PATO_0000327 a rdfs:Class ;
rdfs:label "low brightness" ;
rdfs:comment "A color brightness which is relatively low." ;
rdfs:subClassOf obo:PATO_0000016 .
obo:CHEBI_24921 a rdfs:Class ;
rdfs:label "isoquinoline alkaloid" ;
rdfs:comment "Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine." ;
rdfs:subClassOf obo:CHEBI_22315 .
obo:WBPhenotype_0001305 a rdfs:Class ;
rdfs:label "hook morphology variant" ;
rdfs:comment "Any variation in the form or composition of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating." ;
rdfs:subClassOf obo:WBPhenotype_0000070 .
obo:GO_0062013 a rdfs:Class ;
rdfs:label "positive regulation of small molecule metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0062012 , obo:GO_0065007 .
obo:WBPhenotype_0000369 a rdfs:Class ;
rdfs:label "pretzel arrest" ;
rdfs:comment "Cessation of development during the final two stages in embryogenesis, 'early pretzel' stage and 'late pretzel' stage, just prior to hatching. The animal now is folded into four lengths within the eggshell and resembles a pretzel. By early pretzel stage, the head begins to move independently from the body (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000779 .
obo:WBPhenotype_0000549 a rdfs:Class ;
rdfs:label "head muscle dystrophy" ;
rdfs:comment "Progressive degeneration of the head muscle." ;
rdfs:subClassOf obo:WBPhenotype_0000548 , obo:WBPhenotype_0001002 .
obo:CHEBI_51702 a rdfs:Class ;
rdfs:label "enoate ester" ;
rdfs:comment "An α,β-unsaturated carboxylic ester of general formula R1R2C=CR3‒C(=O)OR4 (R4 ≠ H) in which the ester C=O function is conjugated to a C=C double bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_51737 , obo:CHEBI_78840 .
obo:WBPhenotype_0000054 a rdfs:Class ;
rdfs:label "larval lethal" ;
rdfs:comment "The animal dies at any time between hatching and onset to adulthood." ;
rdfs:subClassOf obo:WBPhenotype_0000062 .
obo:GO_0051247 a rdfs:Class ;
rdfs:label "positive regulation of protein metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." ;
rdfs:subClassOf obo:GO_0010604 , obo:GO_0051246 , obo:GO_0065007 .
obo:GO_1901993 a rdfs:Class ;
rdfs:label "regulation of meiotic cell cycle phase transition" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901987 , obo:GO_2000241 .
obo:GO_2001228 a rdfs:Class ;
rdfs:label "regulation of response to gamma radiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of response to gamma radiation." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 .
obo:PATO_0000008 a rdfs:Class ;
rdfs:label "speed" ;
rdfs:comment "A physical quality inhering in a bearer by virtue of the bearer's scalar absolute value of the rate of change of the bearer's position." ;
rdfs:subClassOf obo:PATO_0001906 .
obo:WBPhenotype_0001641 a rdfs:Class ;
rdfs:label "posterior body wall contraction defective" ;
rdfs:comment "Animals lack or exhibit defects in the posterior body muscle contractions during the defecation cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000157 .
obo:WBPhenotype_0002551 a rdfs:Class ;
rdfs:label "anatomical phenotype"@en ;
rdfs:comment "A phenotype affecting a particular anatomical entity." ;
rdfs:subClassOf obo:WBPhenotype_0000886 .
obo:GO_0045964 a rdfs:Class ;
rdfs:label "positive regulation of dopamine metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ;
rdfs:subClassOf obo:GO_0033240 , obo:GO_0042053 , obo:GO_0065007 .
obo:CHEBI_26822 a rdfs:Class ;
rdfs:label "sulfide" ;
rdfs:comment "Any sulfur molecular entity that involves either covalently bonded or anionic sulfur." ;
rdfs:subClassOf obo:CHEBI_26835 .
obo:CHEBI_33356 a rdfs:Class ;
rdfs:label "iron group element atom" ;
rdfs:subClassOf obo:CHEBI_33561 .
obo:WBPhenotype_0002427 a rdfs:Class ;
rdfs:label "protein aggregation induced associative learning variant" ;
rdfs:comment "Variations in the behavioral plasticity induced by the integration of two sensory signals in response to the aggregation of proteins." ;
rdfs:subClassOf obo:WBPhenotype_0002425 .
obo:CHEBI_50313 a rdfs:Class ;
rdfs:label "onium cation" ;
rdfs:comment "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." ;
rdfs:subClassOf obo:CHEBI_50312 .
obo:WBPhenotype_0002663 a rdfs:Class ;
rdfs:label "intracellular lipid surveillance response abnormal"@en ;
rdfs:comment "Cells of the animal exhibit variations in the intracellular lipid surveillance response, responsible for responding to and addressing lipid depletion inside of cells, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:PATO_0001559 a rdfs:Class ;
rdfs:label "having extra function" ;
rdfs:comment "A functionality quality which is held by the bearer when the latter is able to perform additional or different function(s)." ;
rdfs:subClassOf obo:PATO_0001509 , obo:PATO_0002305 .
obo:WBPhenotype_0001760 a rdfs:Class ;
rdfs:label "G tract instability" ;
rdfs:comment "Animals exhibit an increase in the rate of deletion events in mono-G or G-rich tracts within the genome compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000000 .
obo:GO_0065008 a rdfs:Class ;
rdfs:label "regulation of biological quality" ;
rdfs:comment "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." ;
rdfs:subClassOf obo:GO_0065007 .
obo:GO_0009892 a rdfs:Class ;
rdfs:label "negative regulation of metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0048523 , obo:GO_0065007 .
obo:CHEBI_33937 a rdfs:Class ;
rdfs:label "macronutrient" ;
rdfs:comment "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." ;
rdfs:subClassOf obo:CHEBI_33284 .
obo:WBPhenotype_0002610 a rdfs:Class ;
rdfs:label "ectopic apoptosis"@en ;
rdfs:comment "Apoptosis occurs in cells or cell types that do not undergo apoptosis in controls." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:GO_0015931 a rdfs:Class ;
rdfs:label "nucleobase-containing compound transport" ;
rdfs:comment "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0071705 .
obo:CHEBI_26394 a rdfs:Class ;
rdfs:label "purine nucleoside" ;
rdfs:subClassOf obo:CHEBI_26401 , obo:CHEBI_33838 .
obo:WBPhenotype_0000290 a rdfs:Class ;
rdfs:label "sperm absent" ;
rdfs:comment "Animals lack fully specialized male gametes that are competent for fertilization." ;
rdfs:subClassOf obo:WBPhenotype_0000395 , obo:WBPhenotype_0002552 .
obo:GO_0007060 a rdfs:Class ;
rdfs:label "male meiosis chromosome segregation" ;
rdfs:comment "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male." ;
rdfs:subClassOf obo:GO_0045132 .
obo:WBPhenotype_0000980 a rdfs:Class ;
rdfs:label "pharyngeal contraction variant" ;
rdfs:comment "Any variation in the muscle contractions that control feeding compared to control. Contractions are necessary for bacterial uptake from the surrounding environment." ;
rdfs:subClassOf obo:WBPhenotype_0000634 .
obo:WBPhenotype_0000976 a rdfs:Class ;
rdfs:label "ventral cord patterning variant" ;
rdfs:comment "Any variation in the developmental process that results in the creation of defined areas or spaces within the ventral cord to which cells respond and eventually are instructed to differentiate compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000515 , obo:WBPhenotype_0002551 .
obo:WBPhenotype_0002026 a rdfs:Class ;
rdfs:label "differential touch sensitivity variant" ;
rdfs:comment "Animals differ from control animals in response to mechanical stimulation targeting different parts of the same cell. In N2 wild-type animals, response to touch near the ALM cell body is reduced compared with touch of the cell area near the second pharyngeal bulb." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:GO_0010975 a rdfs:Class ;
rdfs:label "regulation of neuron projection development" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120035 .
obo:CHEBI_33608 a rdfs:Class ;
rdfs:label "hydrogen molecular entity" ;
rdfs:subClassOf obo:CHEBI_33674 .
obo:GO_1905831 a rdfs:Class ;
rdfs:label "negative regulation of spindle assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0051494 , obo:GO_0065007 , obo:GO_0090169 , obo:GO_1902116 .
obo:WBPhenotype_0001259 a rdfs:Class ;
rdfs:label "hermaphrodite fertility reduced" ;
rdfs:comment "Hermaphrodites exhibit a reduction in the production of new individuals owing to defects in gamete competence and/or function compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000806 .
obo:WBbt_0005784 a rdfs:Class ;
rdfs:label "germ line" ;
rdfs:comment "cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes." ;
rdfs:subClassOf obo:WBbt_0005729 .
obo:CHEBI_26912 a rdfs:Class ;
rdfs:label "oxolanes" ;
rdfs:comment "Any oxacycle having an oxolane (tetrahydrofuran) skeleton." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 .
obo:WBPhenotype_0004028 a rdfs:Class ;
rdfs:label "slowing response on food variant" ;
rdfs:comment "Animals exhibit variations in modulating their locomotory rate in response to its food , compared to control. Basal slowing response refers to when well-fed animals move more slowly in the presence of bacteria than in the absence of bacteria . Second , food-deprived control animals , when transferred to bacteria , display a dramatically enhanced slowing response that ensures that the animals do not leave their newly encountered source of food." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:WBPhenotype_0000233 a rdfs:Class ;
rdfs:label "dopamine metabolism variant" ;
rdfs:comment "Animals exhibit variations in any chemical reaction or pathway involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000221 , obo:WBPhenotype_0001518 .
obo:WBPhenotype_0000071 a rdfs:Class ;
rdfs:label "head morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any portion of their anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000532 , obo:WBPhenotype_0000582 .
obo:GO_0010508 a rdfs:Class ;
rdfs:label "positive regulation of autophagy" ;
rdfs:comment "Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0010506 , obo:GO_0065007 .
obo:CHEBI_64246 a rdfs:Class ;
rdfs:label "tunicamycin A2" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a tetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:CHEBI_25897 a rdfs:Class ;
rdfs:label "pentenoic acid" ;
rdfs:comment "Any C5, straight-chain, monounsaturated fatty acid." ;
rdfs:subClassOf obo:CHEBI_25413 , obo:CHEBI_26666 , obo:CHEBI_59202 .
obo:WBPhenotype_0000043 a rdfs:Class ;
rdfs:label "general pace of development variant" ;
rdfs:comment "Variations in the progression time of an animal from pronuclei meeting to adulthood compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000033 .
obo:GO_0140244 a rdfs:Class ;
rdfs:label "regulation of translation at presynapse" ;
rdfs:comment "Any process that regulates translation occurring at the presynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0140243 .
obo:CHEBI_22901 a rdfs:Class ;
rdfs:label "bisphenol" ;
rdfs:comment "By usage, the methylenediphenols, HOC6H4CH2C6H4OH, commonly p,p-methylenediphenol, and their substitution products (generally derived from condensation of two equivalent amounts of a phenol with an aldehyde or ketone). The term also includes analogues in the the methylene (or substituted methylene) group has been replaced by a heteroatom." ;
rdfs:subClassOf obo:CHEBI_33853 .
obo:CHEBI_24621 a rdfs:Class ;
rdfs:label "hormone" ;
rdfs:comment "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." ;
rdfs:subClassOf obo:CHEBI_33280 , obo:CHEBI_48705 .
obo:GO_1903327 a rdfs:Class ;
rdfs:label "negative regulation of tRNA metabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051253 , obo:GO_0065007 , obo:GO_1903326 .
obo:WBbt_0008182 a rdfs:Class ;
rdfs:label "rectal epithelial cell" ;
rdfs:comment "These cells include: B, F, Y, U, K' and K. All rectal epithelial cells contain secretory membrane stacks along this region facing the lumenal cuticle and produce some portion of the cuticular lining of the rectum. These are interfacial cells that connect the alimentary system to the main body syncytium." ;
rdfs:subClassOf obo:WBbt_0005754 .
obo:WBbt_0008374 a rdfs:Class ;
rdfs:label "stoma" ;
rdfs:comment "Portion of the digestive tract between the oral opening and the definitely tri-radiate beginning of the esophagus (pharynx)." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:GO_1990138 a rdfs:Class ;
rdfs:label "neuron projection extension" ;
rdfs:comment "Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite." ;
rdfs:subClassOf obo:GO_0048588 , obo:GO_0060560 .
obo:CHEBI_35367 a rdfs:Class ;
rdfs:label "thiocarboxylic acid anion" ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:WBPhenotype_0001465 a rdfs:Class ;
rdfs:label "acetone chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of acetone. In C. elegans, at specific concentrations, acetone is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0000265 .
obo:WBPhenotype_0010003 a rdfs:Class ;
rdfs:label "cell corpse appearance delayed" ;
rdfs:comment "Animals exhibit a decreased rate programmed cell death pathway leading to the destruction of the cell, viewable in its terminally dismanteled form of a cell corpse, compared to that observed for control cells." ;
rdfs:subClassOf obo:WBPhenotype_0000185 , obo:WBPhenotype_0000438 .
obo:GO_0031348 a rdfs:Class ;
rdfs:label "negative regulation of defense response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." ;
rdfs:subClassOf obo:GO_0031347 , obo:GO_0048585 , obo:GO_0065007 .
obo:WBPhenotype_0001435 a rdfs:Class ;
rdfs:label "ammonium chloride chemotaxis defective" ;
rdfs:comment "Failure in directed movement in response to ammonium chloride compared to control. In C. elegans, NH4Cl is an attractant. NH4Cl has also subsequently been used to assay for Cl- attraction in C. elegans." ;
rdfs:subClassOf obo:WBPhenotype_0001441 , obo:WBPhenotype_0001460 .
obo:WBPhenotype_0004008 a rdfs:Class ;
rdfs:label "sustained spicule protraction defective" ;
rdfs:comment "Males exhibit defects in the prolonged, tonic, spicule extrusion through the vulva prior to sperm transfer." ;
rdfs:subClassOf obo:WBPhenotype_0002443 .
obo:GO_0009888 a rdfs:Class ;
rdfs:label "tissue development" ;
rdfs:comment "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:WBbt_0008448 a rdfs:Class ;
rdfs:label "germline blastomere" ;
rdfs:comment "Embryonic cell that has the developmental potential to generate a germ cell." ;
rdfs:subClassOf obo:WBbt_0007028 .
obo:CHEBI_16183 a rdfs:Class ;
rdfs:label "methane" ;
rdfs:comment "A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. −161°C)." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_138675 , obo:CHEBI_18310 , obo:CHEBI_37176 , obo:CHEBI_64708 .
obo:CHEBI_78608 a rdfs:Class ;
rdfs:label "alpha-amino-acid zwitterion" ;
rdfs:comment "An amino acid-zwitterion obtained by transfer of a proton from the carboxy to the amino group of any α-amino acid; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:WBPhenotype_0001316 a rdfs:Class ;
rdfs:label "evoked postsynaptic current variant" ;
rdfs:comment "Variations in the synaptic currents that are elicited by firing an action potential in a population of axons, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002014 .
obo:GO_0006911 a rdfs:Class ;
rdfs:label "phagocytosis, engulfment" ;
rdfs:comment "The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis." ;
rdfs:subClassOf obo:GO_0099024 .
obo:CHEBI_33696 a rdfs:Class ;
rdfs:label "nucleic acid" ;
rdfs:comment "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ;
rdfs:subClassOf obo:CHEBI_15986 .
obo:WBPhenotype_0000203 a rdfs:Class ;
rdfs:label "odorant adaptation variant" ;
rdfs:comment "Animals exhibit variations in the characteristic desensitization to a volatile organic chemo-attractive signal in a time-concentration dependent and reversible manner compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001048 .
obo:WBPhenotype_0001602 a rdfs:Class ;
rdfs:label "methiothepin resistant" ;
rdfs:comment "Animals fail to respond to the concentration of methiothepin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001601 .
obo:CHEBI_25435 a rdfs:Class ;
rdfs:label "mutagen" ;
rdfs:comment "An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution." ;
rdfs:subClassOf obo:CHEBI_50902 .
obo:GO_0061387 a rdfs:Class ;
rdfs:label "regulation of extent of cell growth" ;
rdfs:comment "Any process that modulates the extent of cell growth." ;
rdfs:subClassOf obo:GO_0001558 .
obo:CHEBI_33426 a rdfs:Class ;
rdfs:label "chlorine oxoacid" ;
rdfs:subClassOf obo:CHEBI_23117 , obo:CHEBI_33425 .
obo:GO_0090148 a rdfs:Class ;
rdfs:label "membrane fission" ;
rdfs:comment "A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes." ;
rdfs:subClassOf obo:GO_0061024 .
obo:GO_0022408 a rdfs:Class ;
rdfs:label "negative regulation of cell-cell adhesion" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." ;
rdfs:subClassOf obo:GO_0007162 , obo:GO_0022407 , obo:GO_0065007 .
obo:GO_0051222 a rdfs:Class ;
rdfs:label "positive regulation of protein transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051050 , obo:GO_0051223 , obo:GO_0065007 , obo:GO_1903829 , obo:GO_1904951 .
obo:WBPhenotype_0001677 a rdfs:Class ;
rdfs:label "stage specific cuticle antigenicity variant" ;
rdfs:comment "Animals display cuticle components displayed by animals of a different developmental stage, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001687 .
obo:GO_0036464 a rdfs:Class ;
rdfs:label "cytoplasmic ribonucleoprotein granule" ;
rdfs:comment "A ribonucleoprotein granule located in the cytoplasm." ;
rdfs:subClassOf obo:GO_0035770 .
obo:GO_0007292 a rdfs:Class ;
rdfs:label "female gamete generation" ;
rdfs:comment "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." ;
rdfs:subClassOf obo:GO_0007276 .
obo:CHEBI_35352 a rdfs:Class ;
rdfs:label "organonitrogen compound" ;
rdfs:comment "Any heteroorganic entity containing at least one carbon-nitrogen bond." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_51143 .
obo:WBPhenotype_0000387 a rdfs:Class ;
rdfs:label "sperm nonmotile" ;
rdfs:comment "The mature male gametes lack self-propelled movement." ;
rdfs:subClassOf obo:WBPhenotype_0000987 .
obo:WBPhenotype_0001364 a rdfs:Class ;
rdfs:label "male fan morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the flattened structure extending laterally at the extreme tip of the adult male consisting of nine pairs of sensory rays that lie within a web-like cuticle compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000070 .
obo:GO_0043557 a rdfs:Class ;
rdfs:label "regulation of translation in response to osmotic stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ;
rdfs:subClassOf obo:GO_0043555 , obo:GO_0065007 .
obo:GO_0051453 a rdfs:Class ;
rdfs:label "regulation of intracellular pH" ;
rdfs:comment "Any process that modulates the internal pH of a cell, corresponding to a change in hydrogen ion concentration." ;
rdfs:subClassOf obo:GO_0006885 , obo:GO_0030003 , obo:GO_0065008 .
obo:GO_1901608 a rdfs:Class ;
rdfs:label "regulation of vesicle transport along microtubule" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902513 .
obo:GO_1900074 a rdfs:Class ;
rdfs:label "negative regulation of neuromuscular synaptic transmission" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission." ;
rdfs:subClassOf obo:GO_0050805 , obo:GO_0065007 , obo:GO_1900073 .
obo:WBPhenotype_0001491 a rdfs:Class ;
rdfs:label "obsolete anterior region morphology abnormal" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0001896 a rdfs:Class ;
rdfs:label "gamma ray induced apoptosis decreased" ;
rdfs:comment "Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000182 , obo:WBPhenotype_0001326 .
obo:CHEBI_25195 a rdfs:Class ;
rdfs:label "mercury atom" ;
rdfs:subClassOf obo:CHEBI_33340 .
obo:GO_0045185 a rdfs:Class ;
rdfs:label "maintenance of protein location" ;
rdfs:comment "Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away." ;
rdfs:subClassOf obo:GO_0051235 .
obo:WBbt_0005785 a rdfs:Class ;
rdfs:label "somatic gonad" ;
rdfs:comment "The components of the gonad that are separate from the germline proper. In hermaphrodite, these include five tissues which are all derived from the somatic primordium : the distal tip cells, the gonadal sheath, the spermatheca, the spermatheca-uterine valve (sp-ut) and the uterus." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:GO_0033240 a rdfs:Class ;
rdfs:label "positive regulation of amine metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0033238 , obo:GO_0065007 .
obo:GO_1904170 a rdfs:Class ;
rdfs:label "regulation of bleb assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of bleb assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120032 .
obo:GO_0008037 a rdfs:Class ;
rdfs:label "cell recognition" ;
rdfs:comment "The process in which a cell in an organism interprets its surroundings." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0005886 a rdfs:Class ;
rdfs:label "plasma membrane" ;
rdfs:comment "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." ;
rdfs:subClassOf obo:GO_0016020 .
obo:PATO_0001794 a rdfs:Class ;
rdfs:label "coiling" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the bearer's being wound in a continuous series of loops." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:CHEBI_33635 a rdfs:Class ;
rdfs:label "polycyclic compound" ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:GO_0031115 a rdfs:Class ;
rdfs:label "negative regulation of microtubule polymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." ;
rdfs:subClassOf obo:GO_0031111 , obo:GO_0031113 , obo:GO_0032272 , obo:GO_0065007 , obo:GO_1902904 .
obo:WBPhenotype_0002223 a rdfs:Class ;
rdfs:label "manganese hypersensitivity" ;
rdfs:comment "Animals respond at a faster rate or to lower concentrations of manganese that that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001863 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000076 a rdfs:Class ;
rdfs:label "epithelial attachment variant" ;
rdfs:comment "Variations in the adhesion of the layer of cells that cover the external surface of an organism which serves to protect the animal from external environment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000608 .
obo:GO_2001234 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic signaling pathway" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway." ;
rdfs:subClassOf obo:GO_0009968 , obo:GO_0043066 , obo:GO_0065007 , obo:GO_2001233 .
obo:WBPhenotype_0000359 a rdfs:Class ;
rdfs:label "tunicamycin response variant" ;
rdfs:comment "Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0001613 a rdfs:Class ;
rdfs:label "paralysis response to ethanol resistant" ;
rdfs:comment "Animals in the presence of ethanol continue to respond to touch under conditions when control worms have stopped responding to stimuli." ;
rdfs:subClassOf obo:WBPhenotype_0001612 .
obo:GO_1902117 a rdfs:Class ;
rdfs:label "positive regulation of organelle assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of organelle assembly." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0044089 , obo:GO_0065007 , obo:GO_1902115 .
obo:WBPhenotype_0000846 a rdfs:Class ;
rdfs:label "presynaptic region physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process in the region of the vesicle-filled varicosities of the synapse compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000584 .
obo:WBPhenotype_0001456 a rdfs:Class ;
rdfs:label "nonanone chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of nonanone. In C. elegans, nonanone is typically a repellant." ;
rdfs:subClassOf obo:WBPhenotype_0001455 .
obo:WBPhenotype_0000022 a rdfs:Class ;
rdfs:label "long" ;
rdfs:comment "Animals are longer than control animals at the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0000319 , obo:WBPhenotype_0001726 .
obo:WBPhenotype_0000787 a rdfs:Class ;
rdfs:label "posterior pale" ;
rdfs:comment "Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the posterior body axis compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000984 , obo:WBPhenotype_0001261 .
obo:CHEBI_33839 a rdfs:Class ;
rdfs:label "macromolecule" ;
rdfs:comment "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:CHEBI_36357 .
obo:WBls_0000020 a rdfs:Class ;
rdfs:label "3-fold embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000808 .
obo:WBPhenotype_0001327 a rdfs:Class ;
rdfs:label "cell gamma ray hypersensitive" ;
rdfs:comment "Cells respond to a lower dosage of gamma rays or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001326 .
obo:GO_0019219 a rdfs:Class ;
rdfs:label "regulation of nucleobase-containing compound metabolic process" ;
rdfs:comment "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080090 .
obo:WBPhenotype_0000422 a rdfs:Class ;
rdfs:label "twitcher" ;
rdfs:comment "Animals exhibit spasmodic muscle twitching superimposed on normal sinusoidal motion." ;
rdfs:subClassOf obo:WBPhenotype_0001701 .
obo:GO_2000767 a rdfs:Class ;
rdfs:label "positive regulation of cytoplasmic translation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cytoplasmic translation." ;
rdfs:subClassOf obo:GO_0045727 , obo:GO_0065007 , obo:GO_2000765 .
obo:WBPhenotype_0001924 a rdfs:Class ;
rdfs:label "oocytes stacked" ;
rdfs:comment "Oocytes are found one on top of the other in the dorsal to ventral orientation in the gonad." ;
rdfs:subClassOf obo:WBPhenotype_0001260 .
obo:WBPhenotype_0001019 a rdfs:Class ;
rdfs:label "mid larval arrest" ;
rdfs:comment "Animals arrest during the stage between early and late larval development. In C. elegans, mid larval arrest occurs during the L2 to L3 stages of development." ;
rdfs:subClassOf obo:WBPhenotype_0000059 .
obo:CHEBI_51959 a rdfs:Class ;
rdfs:label "organic tricyclic compound" ;
rdfs:subClassOf obo:CHEBI_51958 .
obo:WBbt_0006800 a rdfs:Class ;
rdfs:label "spermatid" ;
rdfs:comment "An immature sperm cell which undergoes morphogenesis to form mature, amoeboid sperm." ;
rdfs:subClassOf obo:WBbt_0006796 .
obo:CHEBI_149552 a rdfs:Class ;
rdfs:label "emetic" ;
rdfs:comment "Any agent that induces nausea and vomiting." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0033262 a rdfs:Class ;
rdfs:label "regulation of nuclear cell cycle DNA replication" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0065007 , obo:GO_0090329 .
obo:WBbt_0004946 a rdfs:Class ;
rdfs:label "TL" ;
rdfs:comment "Tail seam hypodermal cell, postembryonic blast cell, functions as phasmid socket in L1" ;
rdfs:subClassOf obo:WBbt_0005753 , obo:WBbt_0008409 .
obo:WBbt_0005774 a rdfs:Class ;
rdfs:label "cloaca" ;
rdfs:comment "a feature of the male tail, caudal to the proctodeum, where the vas deferens and the intestine open out jointly near the tail tip to discharge their contents." ;
rdfs:subClassOf obo:WBbt_0005757 .
obo:GO_0042754 a rdfs:Class ;
rdfs:label "negative regulation of circadian rhythm" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior." ;
rdfs:subClassOf obo:GO_0042752 , obo:GO_0048519 , obo:GO_0065007 .
obo:PATO_0000955 a rdfs:Class ;
rdfs:label "fertile" ;
rdfs:comment "A fertility quality inhering in a bearer by virtue of the bearer's being capable of initiating, sustaining, or supporting reproduction." ;
rdfs:subClassOf obo:PATO_0000274 .
obo:CHEBI_15366 a rdfs:Class ;
rdfs:label "acetic acid" ;
rdfs:comment "A simple monocarboxylic acid containing two carbons." ;
rdfs:subClassOf obo:CHEBI_25384 .
obo:CHEBI_63490 a rdfs:Class ;
rdfs:label "explosive" ;
rdfs:comment "A substance capable of undergoing rapid and highly exothermic decomposition." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:GO_0051493 a rdfs:Class ;
rdfs:label "regulation of cytoskeleton organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:WBPhenotype_0001893 a rdfs:Class ;
rdfs:label "mitochondrial membrane potential reduced" ;
rdfs:comment "Any reduction in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001282 .
obo:GO_0051318 a rdfs:Class ;
rdfs:label "G1 phase" ;
rdfs:comment "The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis." ;
rdfs:subClassOf obo:GO_0022403 .
obo:GO_1902969 a rdfs:Class ;
rdfs:label "mitotic DNA replication" ;
rdfs:comment "Any nuclear DNA replication that is involved in a mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0033260 , obo:GO_1903047 .
obo:PATO_0000639 a rdfs:Class ;
rdfs:label "degenerate" ;
rdfs:comment "A structural quality inhering in a bearer whose structure deteriorates or is lost over time due to an active pathological process." ;
rdfs:subClassOf obo:PATO_0002037 .
obo:PATO_0000188 a rdfs:Class ;
rdfs:label "coordination" ;
rdfs:comment "A behavioral quality inhering in a bearer by virtue of the bearer's having or lacking skillful and effective interaction of movement." ;
rdfs:subClassOf obo:PATO_0000186 .
obo:GO_1900063 a rdfs:Class ;
rdfs:label "regulation of peroxisome organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of peroxisome organization." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:WBPhenotype_0001056 a rdfs:Class ;
rdfs:label "iodide chemotaxis defective" ;
rdfs:comment "Animals fail to exhibit the same taxis behavior as control animals in response to iodide. In C. elegans, this is characterized by the failure to move towards iodide." ;
rdfs:subClassOf obo:WBPhenotype_0001439 , obo:WBPhenotype_0001459 .
obo:GO_1902100 a rdfs:Class ;
rdfs:label "negative regulation of metaphase/anaphase transition of cell cycle" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901988 , obo:GO_1902099 .
obo:GO_0050771 a rdfs:Class ;
rdfs:label "negative regulation of axonogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis." ;
rdfs:subClassOf obo:GO_0010977 , obo:GO_0050768 , obo:GO_0050770 , obo:GO_0065007 .
obo:CHEBI_8081 a rdfs:Class ;
rdfs:label "phentolamine" ;
rdfs:comment "A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An α-adrenergic antagonist, it is used for the treatment of hypertension." ;
rdfs:subClassOf obo:CHEBI_24780 , obo:CHEBI_33853 , obo:CHEBI_48975 , obo:CHEBI_50996 .
obo:WBPhenotype_0001111 a rdfs:Class ;
rdfs:label "aster AB defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the AB cell." ;
rdfs:subClassOf obo:WBPhenotype_0001110 .
obo:GO_0005863 a rdfs:Class ;
rdfs:label "striated muscle myosin thick filament" ;
rdfs:comment "Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils." ;
rdfs:subClassOf obo:GO_0032982 , obo:GO_0036379 .
obo:GO_0008641 a rdfs:Class ;
rdfs:label "ubiquitin-like modifier activating enzyme activity" ;
rdfs:comment "Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond." ;
rdfs:subClassOf obo:GO_0016877 , obo:GO_0140096 , obo:GO_0140657 .
obo:BFO_0000020 a rdfs:Class ;
rdfs:label "specifically dependent continuant"@en ;
rdfs:comment "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:GO_0034763 a rdfs:Class ;
rdfs:label "negative regulation of transmembrane transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0034762 , obo:GO_0048523 , obo:GO_0051051 , obo:GO_0065007 .
obo:WBPhenotype_0002288 a rdfs:Class ;
rdfs:label "tail bend angle variant" ;
rdfs:comment "Any variation in the extent of the maximum flex of the most posterior portion of the animal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002287 .
obo:GO_0032240 a rdfs:Class ;
rdfs:label "negative regulation of nucleobase-containing compound transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032239 , obo:GO_0051051 , obo:GO_0065007 .
obo:CHEBI_24067 a rdfs:Class ;
rdfs:label "fluoroalkane" ;
rdfs:comment "A haloalkane that is an alkane in which at least one hydrogen atom has been replaced by a fluorine atom." ;
rdfs:subClassOf obo:CHEBI_24469 , obo:CHEBI_37143 .
obo:WBPhenotype_0000033 a rdfs:Class ;
rdfs:label "developmental timing variant" ;
rdfs:comment "The timing of specific developmental events in some tissues is altered relative to the timing of events in other tissues." ;
rdfs:subClassOf obo:WBPhenotype_0000531 .
obo:WBPhenotype_0000987 a rdfs:Class ;
rdfs:label "germ cell physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the germ cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:CHEBI_36339 a rdfs:Class ;
rdfs:label "baryon" ;
rdfs:comment "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek βαρυσ (heavy)." ;
rdfs:subClassOf obo:CHEBI_36340 , obo:CHEBI_36344 .
obo:CHEBI_37838 a rdfs:Class ;
rdfs:label "carboacyl group" ;
rdfs:comment "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." ;
rdfs:subClassOf obo:CHEBI_22221 .
obo:CHEBI_33560 a rdfs:Class ;
rdfs:label "p-block element atom" ;
rdfs:comment "Any main group element atom belonging to the p-block of the periodic table." ;
rdfs:subClassOf obo:CHEBI_33318 .
obo:GO_0007093 a rdfs:Class ;
rdfs:label "mitotic cell cycle checkpoint signaling" ;
rdfs:comment "A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage." ;
rdfs:subClassOf obo:GO_0000075 , obo:GO_0045930 , obo:GO_1903047 .
obo:GO_1905550 a rdfs:Class ;
rdfs:label "regulation of protein localization to endoplasmic reticulum" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_0031344 a rdfs:Class ;
rdfs:label "regulation of cell projection organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:WBPhenotype_0002555 a rdfs:Class ;
rdfs:label "organismal phenotype"@en ;
rdfs:comment "A phenotype affecting the whole organism." ;
rdfs:subClassOf obo:WBPhenotype_0002551 .
obo:WBPhenotype_0001003 a rdfs:Class ;
rdfs:label "L4 lethal" ;
rdfs:comment "Animals die at the L4 stage of the life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000058 .
obo:GO_0090307 a rdfs:Class ;
rdfs:label "mitotic spindle assembly" ;
rdfs:comment "Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied." ;
rdfs:subClassOf obo:GO_0007052 , obo:GO_0051225 .
obo:CHEBI_64915 a rdfs:Class ;
rdfs:label "antiplasmodial drug" ;
rdfs:comment "An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria." ;
rdfs:subClassOf obo:CHEBI_35820 .
obo:GO_0071166 a rdfs:Class ;
rdfs:label "ribonucleoprotein complex localization" ;
rdfs:comment "Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell." ;
rdfs:subClassOf obo:GO_0051641 .
obo:CHEBI_23451 a rdfs:Class ;
rdfs:label "cyclitol" ;
rdfs:comment "A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom." ;
rdfs:subClassOf obo:CHEBI_26191 .
obo:WBPhenotype_0000348 a rdfs:Class ;
rdfs:label "obsolete muscle activation defective" ;
rdfs:comment "OBSOLETE." .
obo:WBls_0000104 a rdfs:Class ;
rdfs:label "nematode adult" ;
rdfs:comment "The nematode life-stage that begins when the organism is fully-developed and has reached maturity." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000101 .
obo:CHEBI_38534 a rdfs:Class ;
rdfs:label "1-(methylsulfanyl)acetaldoxime" ;
rdfs:subClassOf obo:CHEBI_86315 .
obo:CHEBI_37163 a rdfs:Class ;
rdfs:label "glucan" ;
rdfs:comment "A polysaccharide composed of glucose residues." ;
rdfs:subClassOf obo:CHEBI_37164 .
obo:WBPhenotype_0001991 a rdfs:Class ;
rdfs:label "hypoxia response attenuated" ;
rdfs:comment "Response to low levels of oxygen is reduced or weakened compared to the response of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002423 .
obo:GO_0031430 a rdfs:Class ;
rdfs:label "M band" ;
rdfs:comment "The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0002031 a rdfs:Class ;
rdfs:label "lectin response variant" ;
rdfs:comment "Exposure to carbohydrate binding gene products result in an altered action in comparison to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000459 , obo:WBPhenotype_0001210 .
obo:WBPhenotype_0002229 a rdfs:Class ;
rdfs:label "chromium response variant" ;
rdfs:comment "Animals exhibit variations in their response to chromium compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000591 .
obo:WBPhenotype_0002294 a rdfs:Class ;
rdfs:label "body posture wavelength variant" ;
rdfs:comment "Animals exhibit variations in body posture with regard to the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal." ;
rdfs:subClassOf obo:WBPhenotype_0000001 .
obo:WBPhenotype_0000433 a rdfs:Class ;
rdfs:label "DNA synthesis variant" ;
rdfs:comment "Variations in the processes involving the production of new DNA strands compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000732 .
obo:CHEBI_139588 a rdfs:Class ;
rdfs:label "alpha-hydroxy ketone" ;
rdfs:comment "A ketone containing a hydroxy group on the α-carbon relative to the C=O group." ;
rdfs:subClassOf obo:CHEBI_17087 , obo:CHEBI_33822 .
obo:CHEBI_46695 a rdfs:Class ;
rdfs:label "fluorohydrocarbon" ;
rdfs:comment "A compound derived from a hydrocarbon by replacing one or more hydrogen atoms with fluorine atoms." ;
rdfs:subClassOf obo:CHEBI_24472 , obo:CHEBI_37143 .
obo:CHEBI_16646 a rdfs:Class ;
rdfs:label "carbohydrate" ;
rdfs:comment "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." ;
rdfs:subClassOf obo:CHEBI_78616 .
obo:WBPhenotype_0000716 a rdfs:Class ;
rdfs:label "muscle cell attachment variant" ;
rdfs:comment "Any variation in the connection of a cell whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000990 .
obo:WBPhenotype_0002476 a rdfs:Class ;
rdfs:label "pharynx length increased" ;
rdfs:comment "Animals have an increase in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002475 .
obo:WBPhenotype_0010001 a rdfs:Class ;
rdfs:label "cell growth variant" ;
rdfs:comment "Variations in the process(es) by which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000030 , obo:WBPhenotype_0000536 .
obo:GO_1904689 a rdfs:Class ;
rdfs:label "negative regulation of cytoplasmic translational initiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation." ;
rdfs:subClassOf obo:GO_0045947 , obo:GO_0065007 , obo:GO_1904688 .
obo:WBPhenotype_0000757 a rdfs:Class ;
rdfs:label "L3 L4 molt defect" ;
rdfs:comment "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L3 to L4 transition." ;
rdfs:subClassOf obo:WBPhenotype_0000638 .
obo:CHEBI_38032 a rdfs:Class ;
rdfs:label "carbotricyclic compound" ;
rdfs:comment "A carbopolyclic compound comprising of three carbocyclic rings." ;
rdfs:subClassOf obo:CHEBI_35294 , obo:CHEBI_51959 .
obo:WBPhenotype_0000991 a rdfs:Class ;
rdfs:label "obsolete neuron physiology variant" ;
rdfs:comment "OBSOLETE: Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes." .
obo:GO_0010571 a rdfs:Class ;
rdfs:label "positive regulation of nuclear cell cycle DNA replication" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." ;
rdfs:subClassOf obo:GO_0033262 , obo:GO_0065007 , obo:GO_0090068 , obo:GO_2000105 .
obo:PATO_0000616 a rdfs:Class ;
rdfs:label "asymmetrical" ;
rdfs:comment "A symmetry quality inhering in a bearer by virtue of the bearer's lacking symmetry." ;
rdfs:subClassOf obo:PATO_0000965 .
obo:CHEBI_33551 a rdfs:Class ;
rdfs:label "organosulfonic acid" ;
rdfs:comment "An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon." ;
rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_33552 , obo:CHEBI_64709 .
obo:CHEBI_86993 a rdfs:Class ;
rdfs:label "(R)-fluoxetine(1+)" ;
rdfs:comment "An organic cation resulting from the protonation of the amino group of (R)-fluoxetine." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:WBPhenotype_0002471 a rdfs:Class ;
rdfs:label "cilia length increased" ;
rdfs:comment "Animals exhibit an increase in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002470 .
obo:WBPhenotype_0001532 a rdfs:Class ;
rdfs:label "inner labial morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2." ;
rdfs:subClassOf obo:WBPhenotype_0001531 .
obo:WBPhenotype_0001816 a rdfs:Class ;
rdfs:label "egg laying circuit variant" ;
rdfs:comment "Neuromuscular signaling between neurons and egg laying musculature varies from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000929 .
obo:WBbt_0005768 a rdfs:Class ;
rdfs:label "axis" ;
rdfs:comment "spatial axis" ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:CHEBI_36896 a rdfs:Class ;
rdfs:label "monoatomic bromine" ;
rdfs:subClassOf obo:CHEBI_36894 .
obo:GO_0044057 a rdfs:Class ;
rdfs:label "regulation of system process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 .
obo:GO_1902902 a rdfs:Class ;
rdfs:label "negative regulation of autophagosome assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly." ;
rdfs:subClassOf obo:GO_0016242 , obo:GO_0065007 , obo:GO_1902116 , obo:GO_2000785 .
obo:WBbt_0005762 a rdfs:Class ;
rdfs:label "accessory cell" ;
rdfs:comment "cells that support sensory neurons, similar to glial cells in vertebrates. A category which collectively refers to socket cells, sheath cells, and structural cells, or their processes. All of these cells extend long processes which serve a supporting role, rather like glia, to form a protective environment around sensory neuron endings. In addition, some of these cells extend broad thin processes from their somata which wrap around neuronal ganglia, again in a glia-like fashion" ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBPhenotype_0001240 a rdfs:Class ;
rdfs:label "male tail sensory ray differentiation variant" ;
rdfs:comment "Variations in the processes leading to the specialization of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000199 .
obo:GO_0007369 a rdfs:Class ;
rdfs:label "gastrulation" ;
rdfs:comment "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." ;
rdfs:subClassOf obo:GO_0048598 .
obo:CHEBI_83056 a rdfs:Class ;
rdfs:label "Daphnia magna metabolite" ;
rdfs:comment "A Daphnia metabolite produced by the species Daphnia magna." ;
rdfs:subClassOf obo:CHEBI_83057 .
obo:WBPhenotype_0000162 a rdfs:Class ;
rdfs:label "pale larva" ;
rdfs:comment "Larva show deficiencies in chroma resulting in increased translucency." ;
rdfs:subClassOf obo:WBPhenotype_0000890 , obo:WBPhenotype_0001261 .
obo:WBPhenotype_0000222 a rdfs:Class ;
rdfs:label "serotonin metabolism variant" ;
rdfs:comment "Animals exhibit variations in any chemical reaction or pathway involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000221 .
obo:WBPhenotype_0000060 a rdfs:Class ;
rdfs:label "adult lethal" ;
rdfs:comment "Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background." ;
rdfs:subClassOf obo:WBPhenotype_0000062 .
obo:CHEBI_16335 a rdfs:Class ;
rdfs:label "adenosine" ;
rdfs:comment "A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a β‒N9-glycosidic bond." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_142355 , obo:CHEBI_22260 .
obo:WBPhenotype_0000307 a rdfs:Class ;
rdfs:label "dauer pheromone sensation defective" ;
rdfs:comment "Animals fail to detect a pheromone stimulus that induces dauer formation in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001479 .
obo:GO_0050805 a rdfs:Class ;
rdfs:label "negative regulation of synaptic transmission" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." ;
rdfs:subClassOf obo:GO_0010648 , obo:GO_0023057 , obo:GO_0050804 , obo:GO_0065007 .
obo:GO_0050708 a rdfs:Class ;
rdfs:label "regulation of protein secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." ;
rdfs:subClassOf obo:GO_0051223 , obo:GO_0065007 , obo:GO_1903530 .
obo:GO_0045202 a rdfs:Class ;
rdfs:label "synapse" ;
rdfs:comment "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." ;
rdfs:subClassOf obo:GO_0030054 .
obo:CHEBI_146270 a rdfs:Class ;
rdfs:label "oneirogen" ;
rdfs:comment "Any substance that produces or enhances dream-like states of consciousness." ;
rdfs:subClassOf obo:CHEBI_35471 .
obo:GO_2000278 a rdfs:Class ;
rdfs:label "regulation of DNA biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of DNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010556 , obo:GO_0051052 , obo:GO_0065007 .
obo:CHEBI_64767 a rdfs:Class ;
rdfs:label "anionic group" ;
rdfs:comment "A group that carries an overall negative charge." ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:WBPhenotype_0000818 a rdfs:Class ;
rdfs:label "adult behavior variant" ;
rdfs:comment "Activity characteristic of an adult worm is altered compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000819 .
obo:CL_0000228 a rdfs:Class ;
rdfs:label "multinucleate cell" ;
rdfs:comment "A cell with more than one nucleus." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 , obo:CL_0002242 .
obo:WBPhenotype_0001666 a rdfs:Class ;
rdfs:label "organism hypersensitive X ray irradiation" ;
rdfs:comment "Animals respond to iononizing radiation at a lower dose or a shorter exposure compared to control animals. Iononizing radiation has a wavelength in the 10 to 0.01 nanometer range. In C. elegans, increased sensitivity to X-ray irradiation is often observed as a decrease in survival upon exposure compared to control animals given the same treatment." ;
rdfs:subClassOf obo:WBPhenotype_0000276 , obo:WBPhenotype_0000711 .
obo:CHEBI_18099 a rdfs:Class ;
rdfs:label "cyclohexanol" ;
rdfs:comment "An alcohol that consists of cyclohexane bearing a single hydroxy substituent. The parent of the class of cyclohexanols." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_23480 , obo:CHEBI_35681 .
obo:GO_0030590 a rdfs:Class ;
rdfs:label "first cell cycle pseudocleavage" ;
rdfs:comment "A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms." ;
rdfs:subClassOf obo:GO_0030588 .
obo:CHEBI_52557 a rdfs:Class ;
rdfs:label "tetracyclic diterpenoid" ;
rdfs:comment "A diterpenoid with a tetracyclic skeleton." ;
rdfs:subClassOf obo:CHEBI_23849 .
obo:GO_0051445 a rdfs:Class ;
rdfs:label "regulation of meiotic cell cycle" ;
rdfs:comment "Any process that modulates the rate or extent of progression through the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0051726 , obo:GO_0065007 , obo:GO_2000241 .
obo:CHEBI_33459 a rdfs:Class ;
rdfs:label "pnictogen oxoanion" ;
rdfs:subClassOf obo:CHEBI_33302 , obo:CHEBI_35406 .
obo:CL_0000411 a rdfs:Class ;
rdfs:label "Caenorhabditis hypodermal cell" ;
rdfs:comment "An epithelial cell of the hypodermis of Caenorhabditis." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0000228 .
obo:GO_0042221 a rdfs:Class ;
rdfs:label "response to chemical" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ;
rdfs:subClassOf obo:GO_0050896 .
obo:GO_1902807 a rdfs:Class ;
rdfs:label "negative regulation of cell cycle G1/S phase transition" ;
rdfs:comment "Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901988 , obo:GO_1902806 .
obo:WBPhenotype_0001866 a rdfs:Class ;
rdfs:label "reduced pathogen accumulation" ;
rdfs:comment "Animals exhibit a reduction in pathogen accumulation, persistent colonization, and luminal distension of the intestine." ;
rdfs:subClassOf obo:WBPhenotype_0001819 .
obo:GO_0006921 a rdfs:Class ;
rdfs:label "cellular component disassembly involved in execution phase of apoptosis" ;
rdfs:comment "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." ;
rdfs:subClassOf obo:GO_0022411 .
obo:WBPhenotype_0001454 a rdfs:Class ;
rdfs:label "quinine chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of the bitter tastant quinine, a water soluble molecule. In C. elegans, quinine is typically a repellant." ;
rdfs:subClassOf obo:WBPhenotype_0001939 .
obo:GO_1902340 a rdfs:Class ;
rdfs:label "negative regulation of chromosome condensation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation." ;
rdfs:subClassOf obo:GO_0060623 , obo:GO_0065007 , obo:GO_2001251 .
obo:GO_0032273 a rdfs:Class ;
rdfs:label "positive regulation of protein polymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." ;
rdfs:subClassOf obo:GO_0031334 , obo:GO_0032271 , obo:GO_0065007 .
obo:PATO_0001912 a rdfs:Class ;
rdfs:label "physiological state" ;
rdfs:comment "A quality of a single process inhering in a bearer by virtue of the state of bearer's mechanical, physical, and biochemical processes." ;
rdfs:subClassOf obo:PATO_0001236 .
obo:GO_1904350 a rdfs:Class ;
rdfs:label "regulation of protein catabolic process in the vacuole" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole." ;
rdfs:subClassOf obo:GO_0042176 , obo:GO_0065007 .
obo:CHEBI_77022 a rdfs:Class ;
rdfs:label "EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor" ;
rdfs:comment "An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of an acyltransferase which converts the acyl group to an alkyl group on transfer (EC 2.3.3.*)." ;
rdfs:subClassOf obo:CHEBI_76661 .
obo:GO_0042594 a rdfs:Class ;
rdfs:label "response to starvation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0031667 .
obo:GO_0043086 a rdfs:Class ;
rdfs:label "negative regulation of catalytic activity" ;
rdfs:comment "Any process that stops or reduces the activity of an enzyme." ;
rdfs:subClassOf obo:GO_0044092 , obo:GO_0050790 , obo:GO_0065007 .
obo:WBPhenotype_0000173 a rdfs:Class ;
rdfs:label "cell proliferation reduced" ;
rdfs:comment "The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are decreased." ;
rdfs:subClassOf obo:WBPhenotype_0000171 .
obo:GO_0099171 a rdfs:Class ;
rdfs:label "presynaptic modulation of chemical synaptic transmission" ;
rdfs:comment "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." ;
rdfs:subClassOf obo:GO_0050804 .
obo:WBPhenotype_0002460 a rdfs:Class ;
rdfs:label "no induction of antimicrobial peptide expression after infection" ;
rdfs:comment "Animals exhibit no induction of expression of an antimicrobial peptide after an infection, unlike control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001800 , obo:WBPhenotype_0002621 .
obo:CHEBI_36919 a rdfs:Class ;
rdfs:label "antimony molecular entity" ;
rdfs:subClassOf obo:CHEBI_33302 .
obo:GO_1900115 a rdfs:Class ;
rdfs:label "extracellular regulation of signal transduction" ;
rdfs:comment "Any regulation of signal transduction that takes place in the extracellular region." ;
rdfs:subClassOf obo:GO_0009966 .
obo:WBPhenotype_0002302 a rdfs:Class ;
rdfs:label "nose movement decreased" ;
rdfs:comment "Animals exhibit a decrease in the movement of the extreme anterior portion of the body to a new location compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002301 .
obo:PATO_0000047 a rdfs:Class ;
rdfs:label "biological sex" ;
rdfs:comment "An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:CHEBI_65259 a rdfs:Class ;
rdfs:label "GABA antagonist" ;
rdfs:comment "A compound that inhibits the action of γ-aminobutyric acid." ;
rdfs:subClassOf obo:CHEBI_48706 , obo:CHEBI_51374 .
obo:WBPhenotype_0000857 a rdfs:Class ;
rdfs:label "excretory cell development variant" ;
rdfs:comment "Variations in the progression of a protokidney cell with an internal lumen that is suggested to collect and secrete salt solutions outward via the excretory sinus, over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000621 .
obo:WBPhenotype_0001170 a rdfs:Class ;
rdfs:label "sterile F0 48 hours post injection" ;
rdfs:comment "Injected worm stops producing embryos 48 hours after RNAi injection and contains no live/developing embryos at this time." ;
rdfs:subClassOf obo:WBPhenotype_0000689 .
obo:GO_0035437 a rdfs:Class ;
rdfs:label "maintenance of protein localization in endoplasmic reticulum" ;
rdfs:comment "Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0072595 .
obo:GO_2000809 a rdfs:Class ;
rdfs:label "positive regulation of synaptic vesicle clustering" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering." ;
rdfs:subClassOf obo:GO_0051050 , obo:GO_0065007 , obo:GO_2000807 .
obo:GO_1902750 a rdfs:Class ;
rdfs:label "negative regulation of cell cycle G2/M phase transition" ;
rdfs:comment "Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901988 , obo:GO_1902749 .
obo:WBPhenotype_0001200 a rdfs:Class ;
rdfs:label "gonad sheath contraction rate reduced" ;
rdfs:comment "Basal contraction rate and or peak contraction rate of the gonadal sheath is reduced relative to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001199 .
obo:WBPhenotype_0001398 a rdfs:Class ;
rdfs:label "neurite morphology variant" ;
rdfs:comment "Animals display variations in the structure, organization of components, or spatial pattern of any projection stemming from a neuronal cell, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000905 , obo:WBPhenotype_0002089 .
obo:GO_0040029 a rdfs:Class ;
rdfs:label "epigenetic regulation of gene expression" ;
rdfs:comment "A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal." ;
rdfs:subClassOf obo:GO_0006338 , obo:GO_0010468 .
obo:GO_0043186 a rdfs:Class ;
rdfs:label "P granule" ;
rdfs:comment "A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes." ;
rdfs:subClassOf obo:GO_0036464 .
obo:GO_0032940 a rdfs:Class ;
rdfs:label "secretion by cell" ;
rdfs:comment "The controlled release of a substance by a cell." ;
rdfs:subClassOf obo:GO_0046903 , obo:GO_0140352 .
obo:GO_0051236 a rdfs:Class ;
rdfs:label "establishment of RNA localization" ;
rdfs:comment "The directed movement of RNA to a specific location." ;
rdfs:subClassOf obo:GO_0051234 .
obo:NCBITaxon_2759 a rdfs:Class .
obo:WBPhenotype_0001688 a rdfs:Class ;
rdfs:label "surface coat variant" ;
rdfs:comment "The electron dense, amorphous envelope that comprises the outermost layer of the cuticle varies in composition from that observed in control animals of the same developmental stage. The integrity of the surface coat is often revealed by an altered antigenicity or biochemical make up." ;
rdfs:subClassOf obo:WBPhenotype_0000201 , obo:WBPhenotype_0001678 .
obo:WBPhenotype_0002213 a rdfs:Class ;
rdfs:label "kinase activity reduced" ;
rdfs:comment "Any variation that results in a decrease in the catalytic phosphorylation activity of a kinase enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component). Kinases are enzymes capable of phosphorylating their respective substrates." ;
rdfs:subClassOf obo:WBPhenotype_0000124 .
obo:WBPhenotype_0004017 a rdfs:Class ;
rdfs:label "locomotor coordination variant" ;
rdfs:comment "Animals exhibit variations in their ability to maintain characteristic and effective locomotion compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000643 .
obo:WBPhenotype_0000768 a rdfs:Class ;
rdfs:label "cytoplasmic structure defective early emb" ;
rdfs:comment "Areas devoid of yolk granules throughout the embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001081 .
obo:CL_0000067 a rdfs:Class ;
rdfs:label "ciliated epithelial cell" ;
rdfs:comment "An epithelial cell that has a cilia." ;
rdfs:subClassOf obo:CL_0000064 , obo:CL_0000066 .
obo:CHEBI_131604 a rdfs:Class ;
rdfs:label "Mycoplasma genitalium metabolite" ;
rdfs:comment "Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium." ;
rdfs:subClassOf obo:CHEBI_76969 .
obo:WBPhenotype_0002299 a rdfs:Class ;
rdfs:label "coiling frequency decreased" ;
rdfs:comment "Animals spend less time with their body posture in a coil or they decrease the frequency with which they form coils compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002298 .
obo:CHEBI_35443 a rdfs:Class ;
rdfs:label "anthelminthic drug" ;
rdfs:comment "Substance intended to kill parasitic worms (helminths)." ;
rdfs:subClassOf obo:CHEBI_35442 .
obo:WBPhenotype_0001792 a rdfs:Class ;
rdfs:label "nuclei small" ;
rdfs:comment "Nuclei of specific cells are smaller compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002607 .
obo:WBbt_0005745 a rdfs:Class ;
rdfs:label "pseudocoelom" ;
rdfs:comment "A fluid-filled space enclosed on the outside by the basal laminae of the bodywall tissues, principally those of the bodywall muscles and the hypodermis. Within this space the digestive tract and reproductive tract lie separately, each enclosed by its own basal lamina. Intercellular signals, nutrients and waste products can travel between all tissues bordering this space." ;
rdfs:subClassOf obo:WBbt_0005732 , obo:WBbt_0005738 .
obo:CHEBI_137980 a rdfs:Class ;
rdfs:label "metalloid atom" ;
rdfs:comment "An atom of an element that exhibits properties that are between those of metals and nonmetals, or that has a mixture of them. The term generally includes boron, silicon, germanium, arsenic, antimony, and tellurium, while carbon, aluminium, selenium, polonium, and astatine are less commonly included." ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:WBPhenotype_0001223 a rdfs:Class ;
rdfs:label "germline RNAi resistant" ;
rdfs:comment "Animals show reduced susceptibility to gene silencing in the germline triggered by double stranded RNA (RNAi), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001208 .
obo:WBbt_0005839 a rdfs:Class ;
rdfs:label "odorsensory neuron" ;
rdfs:comment "neuron that senses volatile odorants" ;
rdfs:subClassOf obo:WBbt_0005759 .
obo:WBbt_0005744 a rdfs:Class ;
rdfs:label "reproductive tract" ;
rdfs:subClassOf obo:WBbt_0005738 .
obo:WBPhenotype_0002251 a rdfs:Class ;
rdfs:label "silver nanoparticle hypersensitive" ;
rdfs:comment "Animals respond to silver nanoparticles (AgNPs) at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002250 .
obo:GO_0008306 a rdfs:Class ;
rdfs:label "associative learning" ;
rdfs:comment "Learning by associating a stimulus (the cause) with a particular outcome (the effect)." ;
rdfs:subClassOf obo:GO_0007612 .
obo:WBPhenotype_0002332 a rdfs:Class ;
rdfs:label "track length variant" ;
rdfs:comment "Animals exhibit variations in the length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope." ;
rdfs:subClassOf obo:WBPhenotype_0000001 .
obo:GO_0033365 a rdfs:Class ;
rdfs:label "protein localization to organelle" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within an organelle." ;
rdfs:subClassOf obo:GO_0008104 .
obo:CHEBI_24780 a rdfs:Class ;
rdfs:label "imidazoles" ;
rdfs:comment "A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." ;
rdfs:subClassOf obo:CHEBI_23677 .
obo:GO_0099081 a rdfs:Class ;
rdfs:label "supramolecular polymer" ;
rdfs:comment "A polymeric supramolecular structure." ;
rdfs:subClassOf obo:GO_0099080 .
obo:GO_0006390 a rdfs:Class ;
rdfs:label "mitochondrial transcription" ;
rdfs:comment "The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase." ;
rdfs:subClassOf obo:GO_0000959 , obo:GO_0006351 .
obo:CHEBI_60809 a rdfs:Class ;
rdfs:label "adjuvant" ;
rdfs:comment "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself." ;
rdfs:subClassOf obo:CHEBI_52217 .
obo:CHEBI_32442 a rdfs:Class ;
rdfs:label "L-cysteinate(1-)" ;
rdfs:comment "The L-enantiomer of cysteinate(1−)." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_32456 , obo:CHEBI_59814 .
obo:WBPhenotype_0000917 a rdfs:Class ;
rdfs:label "excretory duct cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the excretory duct cell compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000601 , obo:WBPhenotype_0000899 .
obo:WBPhenotype_0002214 a rdfs:Class ;
rdfs:label "extra pharyngeal muscle cells" ;
rdfs:comment "Animals contain an excess number of pharyngeal muscle cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate." ;
rdfs:subClassOf obo:WBPhenotype_0001635 .
obo:GO_0051329 a rdfs:Class ;
rdfs:label "mitotic interphase" ;
rdfs:comment "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs." ;
rdfs:subClassOf obo:GO_0051325 , obo:GO_0098763 .
obo:WBPhenotype_0000281 a rdfs:Class ;
rdfs:label "male sex muscle development variant" ;
rdfs:comment "Variations in the progression of the muscles of the adult male reproductive system over time form their initial formation to their mature structure compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000669 .
obo:WBPhenotype_0000210 a rdfs:Class ;
rdfs:label "defecation contraction variant" ;
rdfs:comment "Any variation in the stereotyped muscle contractions that result in defecation compared to control . In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp)." ;
rdfs:subClassOf obo:WBPhenotype_0000650 .
obo:GO_0051965 a rdfs:Class ;
rdfs:label "positive regulation of synapse assembly" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ;
rdfs:subClassOf obo:GO_0051962 , obo:GO_0051963 , obo:GO_0065007 , obo:GO_1901890 .
obo:CHEBI_24026 a rdfs:Class ;
rdfs:label "fatty alcohol" ;
rdfs:comment "An aliphatic alcohol consisting of a chain of 3 to greater than 27 carbon atoms. Fatty alcohols may be saturated or unsaturated and may be branched or unbranched." ;
rdfs:subClassOf obo:CHEBI_30879 , obo:CHEBI_61697 .
obo:GO_0031333 a rdfs:Class ;
rdfs:label "negative regulation of protein-containing complex assembly" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0051129 , obo:GO_0065007 .
obo:WBPhenotype_0001558 a rdfs:Class ;
rdfs:label "dauer amphid sensillum variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000256 , obo:WBPhenotype_0001556 .
obo:CHEBI_36416 a rdfs:Class ;
rdfs:label "mancude organic heterotricyclic parent" ;
rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_35571 .
obo:CHEBI_37890 a rdfs:Class ;
rdfs:label "alpha-adrenergic antagonist" ;
rdfs:comment "An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma." ;
rdfs:subClassOf obo:CHEBI_37887 , obo:CHEBI_48539 .
obo:WBbt_0008410 a rdfs:Class ;
rdfs:label "phasmid socket cell" ;
rdfs:comment "Hypodermal socket cell of the phasmid sensillum." ;
rdfs:subClassOf obo:WBbt_0005750 .
obo:WBPhenotype_0001109 a rdfs:Class ;
rdfs:label "P0 spindle rotation delayed early emb" ;
rdfs:comment "P0 spindle rotates late in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0000438 , obo:WBPhenotype_0001107 .
obo:GO_0051052 a rdfs:Class ;
rdfs:label "regulation of DNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." ;
rdfs:subClassOf obo:GO_0019219 , obo:GO_0060255 , obo:GO_0065007 .
obo:GO_0045787 a rdfs:Class ;
rdfs:label "positive regulation of cell cycle" ;
rdfs:comment "Any process that activates or increases the rate or extent of progression through the cell cycle." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0051726 , obo:GO_0065007 .
obo:WBPhenotype_0001245 a rdfs:Class ;
rdfs:label "no transport middle segment cilia" ;
rdfs:comment "The bidirectional transport of molecules along the middle segment of axonemal microtubules of the cilia is absent." ;
rdfs:subClassOf obo:WBPhenotype_0001243 .
obo:WBPhenotype_0001781 a rdfs:Class ;
rdfs:label "hypersensitivity to mutagen" ;
rdfs:comment "Animals are more susceptible than control animals to the effects of a nucleic acid damaging agent. This increased susceptibility is often measured by an increase in the rate of spontaneous mutations or an increased lethality." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:GO_0000957 a rdfs:Class ;
rdfs:label "mitochondrial RNA catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ;
rdfs:subClassOf obo:GO_0000959 , obo:GO_0006401 .
obo:WBPhenotype_0002081 a rdfs:Class ;
rdfs:label "peptide uptake by intestinal cell increased" ;
rdfs:comment "Animals exhibit an increase in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002080 .
obo:GO_0072595 a rdfs:Class ;
rdfs:label "maintenance of protein localization in organelle" ;
rdfs:comment "Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." ;
rdfs:subClassOf obo:GO_0032507 , obo:GO_0045185 .
obo:GO_0044779 a rdfs:Class ;
rdfs:label "meiotic spindle checkpoint signaling" ;
rdfs:comment "A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle." ;
rdfs:subClassOf obo:GO_0031577 , obo:GO_0033313 , obo:GO_1902103 .
obo:CHEBI_59137 a rdfs:Class ;
rdfs:label "(8xi)-cinchonan" ;
rdfs:comment "Cinchonan or its (8S)-epimer." ;
rdfs:subClassOf obo:CHEBI_26513 .
obo:WBPhenotype_0002319 a rdfs:Class ;
rdfs:label "roaming increased" ;
rdfs:comment "Animals exhibit an increase in their high-speed movement in the forward direction with brief backward movement compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000237 , obo:WBPhenotype_0002315 .
obo:GO_0032466 a rdfs:Class ;
rdfs:label "negative regulation of cytokinesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0032465 , obo:GO_0051782 , obo:GO_0065007 .
obo:CHEBI_136859 a rdfs:Class ;
rdfs:label "pro-agent" ;
rdfs:comment "A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:WBPhenotype_0001554 a rdfs:Class ;
rdfs:label "dauer nose morphology variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001545 .
obo:GO_0031090 a rdfs:Class ;
rdfs:label "organelle membrane" ;
rdfs:comment "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." ;
rdfs:subClassOf obo:GO_0016020 .
obo:WBPhenotype_0001838 a rdfs:Class ;
rdfs:label "drug induced gene expression variant" ;
rdfs:comment "Gene expression of an animal is not influenced by drug treatment in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:WBPhenotype_0002671 a rdfs:Class ;
rdfs:label "extended healthspan"@en ;
rdfs:comment "Animals exhibit an extension of healthspan, the period within which animals are or appear to be generally healthy as indicated, for example, by mobility, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002670 .
obo:GO_0006310 a rdfs:Class ;
rdfs:label "DNA recombination" ;
rdfs:comment "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction." ;
rdfs:subClassOf obo:GO_0006259 .
obo:WBPhenotype_0000656 a rdfs:Class ;
rdfs:label "acetylcholine synaptic transmission variant" ;
rdfs:comment "Animals exhibit variations in the process of acetylcholine neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000584 .
obo:WBbt_0008591 a rdfs:Class ;
rdfs:label "primary spermatocyte" ;
rdfs:comment "A diploid immature germ cell which forms in the gonad when a spermatogonial stem cell buds off from the rachis to form a single cell that quickly enters metaphase I and divides to form secondary spermatocytes attached to a residual body." ;
rdfs:subClassOf obo:WBbt_0006799 .
obo:WBPhenotype_0001387 a rdfs:Class ;
rdfs:label "fertilization defect male" ;
rdfs:comment "Failure of male-derived sperm to fuse with an oocyte during sexual reproduction." ;
rdfs:subClassOf obo:WBPhenotype_0000983 .
obo:GO_1905843 a rdfs:Class ;
rdfs:label "regulation of cellular response to gamma radiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cellular response to gamma radiation." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 , obo:GO_2001228 .
obo:WBPhenotype_0000582 a rdfs:Class ;
rdfs:label "organism segment morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any anterior/posterior section of their anatomy compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000535 .
obo:CHEBI_35107 a rdfs:Class ;
rdfs:label "azane" ;
rdfs:comment "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." ;
rdfs:subClassOf obo:CHEBI_35106 .
obo:WBPhenotype_0001888 a rdfs:Class ;
rdfs:label "fat associated bodies increased" ;
rdfs:comment "Animals exhibit an increase in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by increases in the number of BODIPY 493/503 staining." ;
rdfs:subClassOf obo:WBPhenotype_0001901 .
obo:WBPhenotype_0001078 a rdfs:Class ;
rdfs:label "cytokinesis defective early emb" ;
rdfs:comment "Cytokinesis is abnormal in the first or second stages of cell division." ;
rdfs:subClassOf obo:WBPhenotype_0001018 , obo:WBPhenotype_0001100 .
obo:WBPhenotype_0002203 a rdfs:Class ;
rdfs:label "corpse morphology variant" ;
rdfs:comment "Corpses resulting from programmed cell death appear different in size or shape from those of corpses in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:WBPhenotype_0000145 a rdfs:Class ;
rdfs:label "fertility phenotype" ;
rdfs:comment "Animals exhibit variations in the time of onset or duration of the fertile period, or production of new individuals that contain some portion of their genetic material inherited from that organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000613 , obo:WBPhenotype_0002555 .
obo:GO_2000827 a rdfs:Class ;
rdfs:label "mitochondrial RNA surveillance" ;
rdfs:comment "The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion." ;
rdfs:subClassOf obo:GO_0000957 , obo:GO_0071025 , obo:GO_0071026 .
obo:GO_0003365 a rdfs:Class ;
rdfs:label "establishment of cell polarity involved in ameboidal cell migration" ;
rdfs:comment "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." ;
rdfs:subClassOf obo:GO_0030010 .
obo:GO_0051170 a rdfs:Class ;
rdfs:label "import into nucleus" ;
rdfs:comment "The directed movement of substances into the nucleus." ;
rdfs:subClassOf obo:GO_0006913 , obo:GO_0010496 .
obo:WBPhenotype_0001698 a rdfs:Class ;
rdfs:label "heparan sulfate biosynthesis variant" ;
rdfs:comment "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001696 .
obo:CHEBI_26216 a rdfs:Class ;
rdfs:label "potassium atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_22314 .
obo:GO_0009713 a rdfs:Class ;
rdfs:label "catechol-containing compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." ;
rdfs:subClassOf obo:GO_0009712 , obo:GO_0046189 .
obo:WBbt_0006865 a rdfs:Class ;
rdfs:label "distal tip cell" ;
rdfs:comment "somatic cell that situates at the tip of a gonad arm." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBPhenotype_0002100 a rdfs:Class ;
rdfs:label "endosome localization variant" ;
rdfs:comment "Any variation in the subcellular localization of membrane bound organelles, known as endosomes, that traffic material between the plasma membrane and internal compartments of the cell, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002098 .
obo:WBls_0000811 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during fully-elongated embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the fully-elongating embryo life stage" ;
rdfs:subClassOf obo:WBls_0000803 .
obo:GO_0060282 a rdfs:Class ;
rdfs:label "positive regulation of oocyte development" ;
rdfs:comment "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0060281 , obo:GO_0065007 , obo:GO_2000243 .
obo:GO_0007031 a rdfs:Class ;
rdfs:label "peroxisome organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." ;
rdfs:subClassOf obo:GO_0006996 .
obo:WBPhenotype_0001651 a rdfs:Class ;
rdfs:label "growth arrest response to 5 FU resistant" ;
rdfs:comment "Animals grow well during or after exposure to 5-FU under conditions where control animals are growth inhibited." ;
rdfs:subClassOf obo:WBPhenotype_0001649 .
obo:CHEBI_38702 a rdfs:Class ;
rdfs:label "inorganic sodium salt" ;
rdfs:subClassOf obo:CHEBI_24839 , obo:CHEBI_26714 .
obo:PATO_0002083 a rdfs:Class ;
rdfs:label "altered number of" ;
rdfs:comment "Having extra or fewer parts." ;
rdfs:subClassOf obo:PATO_0000051 , obo:PATO_0001555 .
obo:CHEBI_15858 a rdfs:Class ;
rdfs:label "bromide" ;
rdfs:subClassOf obo:CHEBI_16042 , obo:CHEBI_36896 .
obo:CHEBI_33833 a rdfs:Class ;
rdfs:label "heteroarene" ;
rdfs:comment "A heterocyclic compound formally derived from an arene by replacement of one or more methine (‒C=) and/or vinylene (‒CH=CH‒) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous π-electron system characteristic of aromatic systems and a number of out-of-plane π-electrons corresponding to the Hückel rule (4n+2)." ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33659 .
obo:CHEBI_24400 a rdfs:Class ;
rdfs:label "glycoside" ;
rdfs:comment "A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO‒, RS‒, RSe‒, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively." ;
rdfs:subClassOf obo:CHEBI_63161 .
obo:WBPhenotype_0002143 a rdfs:Class ;
rdfs:label "mitochondrial respiratory complex II variant" ;
rdfs:comment "The part of the respiratory chain that catalyzes the oxidation of succinate and connects the TCA cycle with the respiratory chain, differs in activity, composition, or organization, from that of controls." ;
rdfs:subClassOf obo:WBPhenotype_0002142 .
obo:WBPhenotype_0000668 a rdfs:Class ;
rdfs:label "endomitotic oocytes" ;
rdfs:comment "Any variation that results in the presence of mature oocytes with distended polyploid nuclei. In C. elegans, such oocytes mature and exit diakinesis, but are often not properly ovulated or fertilized." ;
rdfs:subClassOf obo:WBPhenotype_0001260 .
obo:GO_0046928 a rdfs:Class ;
rdfs:label "regulation of neurotransmitter secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0051588 , obo:GO_0065007 , obo:GO_1903530 .
obo:WBPhenotype_0001770 a rdfs:Class ;
rdfs:label "endo siRNA binding variant" ;
rdfs:comment "Animals exhibit variations in their selective interactions with small interfering RNA molecules compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:WBPhenotype_0002092 a rdfs:Class ;
rdfs:label "early endosome morphology variant" ;
rdfs:comment "Any variation in the form or composition of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002090 .
obo:GO_0061065 a rdfs:Class ;
rdfs:label "regulation of dauer larval development" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ;
rdfs:subClassOf obo:GO_0061062 , obo:GO_0065007 .
obo:GO_0034644 a rdfs:Class ;
rdfs:label "cellular response to UV" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." ;
rdfs:subClassOf obo:GO_0009411 , obo:GO_0071482 .
obo:CHEBI_24433 a rdfs:Class ;
rdfs:label "group" ;
rdfs:comment "A defined linked collection of atoms or a single atom within a molecular entity." ;
rdfs:subClassOf obo:CHEBI_24431 .
obo:GO_0043057 a rdfs:Class ;
rdfs:label "backward locomotion" ;
rdfs:comment "Posterior movement of an organism, e.g. following the direction of the tail of an animal." ;
rdfs:subClassOf obo:GO_0033058 .
obo:CHEBI_58464 a rdfs:Class ;
rdfs:label "nucleoside 3',5'-cyclic phosphate anion" ;
rdfs:comment "The conjugate base of a nucleoside 3',5'-cyclic phosphate." ;
rdfs:subClassOf obo:CHEBI_58945 .
obo:GO_0048261 a rdfs:Class ;
rdfs:label "negative regulation of receptor-mediated endocytosis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." ;
rdfs:subClassOf obo:GO_0045806 , obo:GO_0048259 , obo:GO_0065007 .
obo:WBPhenotype_0000958 a rdfs:Class ;
rdfs:label "preanal ganglion development variant" ;
rdfs:comment "Any variation in the progression of the ganglion which lies at the posterior limit of the ventral nerve cord in the tail over time from its initial formation to its mature form compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000943 .
obo:GO_0031400 a rdfs:Class ;
rdfs:label "negative regulation of protein modification process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ;
rdfs:subClassOf obo:GO_0031399 , obo:GO_0051248 , obo:GO_0065007 .
obo:CHEBI_38329 a rdfs:Class ;
rdfs:label "oxazolidines" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 , obo:CHEBI_38104 .
obo:WBPhenotype_0001476 a rdfs:Class ;
rdfs:label "anterior body contraction variant" ;
rdfs:comment "Any variation in the defecation motor program that involves the contraction of the anterior body wall muscles compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000210 .
obo:GO_0022414 a rdfs:Class ;
rdfs:label "reproductive process" ;
rdfs:comment "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." ;
rdfs:subClassOf obo:GO_0008150 .
obo:WBPhenotype_0000545 a rdfs:Class ;
rdfs:label "egg retention" ;
rdfs:comment "Eggs are retained in the uterus at a later stage when compared with control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000006 .
obo:WBPhenotype_0001376 a rdfs:Class ;
rdfs:label "transgene expression undetectable cell specific" ;
rdfs:comment "The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection in specific cells." ;
rdfs:subClassOf obo:WBPhenotype_0001375 .
obo:WBPhenotype_0002192 a rdfs:Class ;
rdfs:label "extra sex myoblasts" ;
rdfs:comment "Animals produce an excess number of sex myoblasts compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002175 .
obo:WBPhenotype_0000901 a rdfs:Class ;
rdfs:label "gland cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of gland cells compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002108 .
obo:CHEBI_29917 a rdfs:Class ;
rdfs:label "thiol group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:WBPhenotype_0000139 a rdfs:Class ;
rdfs:label "stress induced lethality variant" ;
rdfs:comment "Animals exhibit variations in survival when exposed to stress stimuli that induce lethality in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:GO_0006611 a rdfs:Class ;
rdfs:label "protein export from nucleus" ;
rdfs:comment "The directed movement of a protein from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0006886 , obo:GO_0051168 .
obo:GO_0032991 a rdfs:Class ;
rdfs:label "protein-containing complex" ;
rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ;
rdfs:subClassOf obo:GO_0005575 .
obo:WBPhenotype_0000623 a rdfs:Class ;
rdfs:label "nervous system development variant" ;
rdfs:comment "Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000530 .
obo:GO_0036494 a rdfs:Class ;
rdfs:label "positive regulation of translation initiation in response to endoplasmic reticulum stress" ;
rdfs:comment "Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress." ;
rdfs:subClassOf obo:GO_0032058 , obo:GO_0036491 , obo:GO_0036493 , obo:GO_0065007 .
obo:GO_0048565 a rdfs:Class ;
rdfs:label "digestive tract development" ;
rdfs:comment "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." ;
rdfs:subClassOf obo:GO_0035295 .
obo:CHEBI_36848 a rdfs:Class ;
rdfs:label "5-hydroxy steroid" ;
rdfs:subClassOf obo:CHEBI_35350 .
obo:CHEBI_35701 a rdfs:Class ;
rdfs:label "ester" ;
rdfs:comment "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:WBPhenotype_0000156 a rdfs:Class ;
rdfs:label "body wall muscle contraction interval during defecation abnormal" ;
rdfs:comment "Any variation in the time interval between successive contractions of the body wall muscles during the defecation motor program compared to cantrol." ;
rdfs:subClassOf obo:WBPhenotype_0000210 .
obo:WBPhenotype_0000188 a rdfs:Class ;
rdfs:label "gonad arm morphology variant" ;
rdfs:comment "Any variation in the 'arm-like' form, structure or composition of the specialized tissue of the reproductive tract that produces gametes compared to control. In C. elegans the reproductive tract in the hermaphrodite has two equivalent gonad 'arms', while the male has a one-armed gonad." ;
rdfs:subClassOf obo:WBPhenotype_0000977 .
obo:WBPhenotype_0002513 a rdfs:Class ;
rdfs:label "thermotaxis variant"@en ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific temperature gradient compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002512 .
obo:PATO_0001894 a rdfs:Class ;
rdfs:label "phenotypic sex" ;
rdfs:comment "An organismal quality inhering in a bearer by virtue of the bearer's physical expression of sexual characteristics." ;
rdfs:subClassOf obo:PATO_0000047 .
obo:WBPhenotype_0000013 a rdfs:Class ;
rdfs:label "dauer defective" ;
rdfs:comment "Failure to form dauer larvae under dauer-inducing conditions." ;
rdfs:subClassOf obo:WBPhenotype_0000637 .
obo:WBPhenotype_0001204 a rdfs:Class ;
rdfs:label "muscimol resistant" ;
rdfs:comment "Animals fail to respond to the concentration of muscimol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 , obo:WBPhenotype_0002047 .
obo:GO_0042435 a rdfs:Class ;
rdfs:label "indole-containing compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0042430 .
obo:WBPhenotype_0000939 a rdfs:Class ;
rdfs:label "male T lineages variant" ;
rdfs:comment "The descendants of TL or TR cells in male animals exhibit any variation in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000809 .
obo:WBPhenotype_0000082 a rdfs:Class ;
rdfs:label "L2 arrest" ;
rdfs:comment "The developmental program of the animals does not continue past the second larval stage (L2)." ;
rdfs:subClassOf obo:WBPhenotype_0000055 , obo:WBPhenotype_0000752 , obo:WBPhenotype_0001019 .
obo:WBPhenotype_0001721 a rdfs:Class ;
rdfs:label "pathogen infected pharynx variant" ;
rdfs:comment "Animals exhibit variations in the extent of pathogen invasion into the pharynx compared to control. This is often measured as the percentage of animals exhibiting a pathogen-invaded pharynx within a given population." ;
rdfs:subClassOf obo:WBPhenotype_0001012 .
obo:WBPhenotype_0001169 a rdfs:Class ;
rdfs:label "pseudocleavage exaggerated early emb" ;
rdfs:comment "Embryos have more pronounced pseudocleavage than normal." ;
rdfs:subClassOf obo:WBPhenotype_0001167 .
obo:GO_0120036 a rdfs:Class ;
rdfs:label "plasma membrane bounded cell projection organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." ;
rdfs:subClassOf obo:GO_0030030 .
obo:GO_0042429 a rdfs:Class ;
rdfs:label "serotonin catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ;
rdfs:subClassOf obo:GO_0019336 , obo:GO_0042428 , obo:GO_0042436 , obo:GO_1901161 .
obo:WBPhenotype_0000675 a rdfs:Class ;
rdfs:label "zygotic lethal" ;
rdfs:comment "Animals die after fusion of gametes without dividing." ;
rdfs:subClassOf obo:WBPhenotype_0000213 .
obo:GO_0000082 a rdfs:Class ;
rdfs:label "G1/S transition of mitotic cell cycle" ;
rdfs:comment "The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated." ;
rdfs:subClassOf obo:GO_0044772 , obo:GO_0044843 .
obo:GO_0007398 a rdfs:Class ;
rdfs:label "ectoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." ;
rdfs:subClassOf obo:GO_0009888 .
obo:WBPhenotype_0001629 a rdfs:Class ;
rdfs:label "egg laying serotonin variant" ;
rdfs:comment "Any variation in egg laying behavior after application of exogenous serotonin compared to control. In C. elegans, serotonin induces egg laying." ;
rdfs:subClassOf obo:WBPhenotype_0001101 , obo:WBPhenotype_0001232 .
obo:WBPhenotype_0004010 a rdfs:Class ;
rdfs:label "precise vulval location variant" ;
rdfs:comment "Any variation in the mating process that includes the male positioning his tail precisely over the vulva so that he may insert his spicules and ejaculate compared to control. In C. elegans precise vulva location (coordinating movement and tail positioning) requires the post cloacal sensillium and the spicules." ;
rdfs:subClassOf obo:WBPhenotype_0000649 .
obo:GO_1902102 a rdfs:Class ;
rdfs:label "regulation of metaphase/anaphase transition of meiotic cell cycle" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901993 , obo:GO_1902099 , obo:GO_1905132 .
obo:GO_0006396 a rdfs:Class ;
rdfs:label "RNA processing" ;
rdfs:comment "Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules." ;
rdfs:subClassOf obo:GO_0044238 .
obo:GO_0042753 a rdfs:Class ;
rdfs:label "positive regulation of circadian rhythm" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior." ;
rdfs:subClassOf obo:GO_0042752 , obo:GO_0048518 , obo:GO_0065007 .
obo:GO_0060293 a rdfs:Class ;
rdfs:label "germ plasm" ;
rdfs:comment "Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line." ;
rdfs:subClassOf obo:GO_0045495 .
obo:WBPhenotype_0000275 a rdfs:Class ;
rdfs:label "organism UV hypersensitive" ;
rdfs:comment "Organisms respond to UV at a lower dose or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000143 .
obo:WBPhenotype_0000640 a rdfs:Class ;
rdfs:label "egg laying variant" ;
rdfs:comment "Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:GO_0009968 a rdfs:Class ;
rdfs:label "negative regulation of signal transduction" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0010648 , obo:GO_0023057 , obo:GO_0048585 , obo:GO_0065007 .
obo:WBPhenotype_0000556 a rdfs:Class ;
rdfs:label "dopamine adaptation variant" ;
rdfs:comment "Animals show variations in their decreased responsiveness after prolonged or repeated exposure to dopamine compared to that in control." ;
rdfs:subClassOf obo:WBPhenotype_0000555 .
obo:WBPhenotype_0002230 a rdfs:Class ;
rdfs:label "metal accumulation increased" ;
rdfs:comment "Animals exhibited higher amounts of internal metal concentrations compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002029 .
obo:GO_0032042 a rdfs:Class ;
rdfs:label "mitochondrial DNA metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving mitochondrial DNA." ;
rdfs:subClassOf obo:GO_0006259 .
obo:WBPhenotype_0001192 a rdfs:Class ;
rdfs:label "calcium signaling in pharynx variant" ;
rdfs:comment "Any variation in the series of molecular signals in which a pharyngeal cell uses calcium ions to convert an extracellular signal into a response, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001191 , obo:WBPhenotype_0002170 .
obo:GO_0035556 a rdfs:Class ;
rdfs:label "intracellular signal transduction" ;
rdfs:comment "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." ;
rdfs:subClassOf obo:GO_0007165 .
obo:WBPhenotype_0002622 a rdfs:Class ;
rdfs:label "decreased recruitment of actin upon wounding"@en ;
rdfs:comment "Animals exhibit decreased recruitment of actin to a site of injury, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001346 , obo:WBPhenotype_0001840 .
obo:GO_0045597 a rdfs:Class ;
rdfs:label "positive regulation of cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0048522 , obo:GO_0051094 , obo:GO_0065007 .
obo:WBPhenotype_0000947 a rdfs:Class ;
rdfs:label "connective tissue morphology variant" ;
rdfs:comment "Variations in the form, structure or composition of the material made up of fibers forming a framework and support structure for body tissues and organs compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000912 .
obo:GO_0097447 a rdfs:Class ;
rdfs:label "dendritic tree" ;
rdfs:comment "The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches." ;
rdfs:subClassOf obo:GO_0043005 .
obo:GO_0050920 a rdfs:Class ;
rdfs:label "regulation of chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ;
rdfs:subClassOf obo:GO_0032101 , obo:GO_0040012 , obo:GO_0065007 .
obo:GO_0048582 a rdfs:Class ;
rdfs:label "positive regulation of post-embryonic development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ;
rdfs:subClassOf obo:GO_0048580 , obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0071173 a rdfs:Class ;
rdfs:label "spindle assembly checkpoint signaling" ;
rdfs:comment "A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle." ;
rdfs:subClassOf obo:GO_0031577 .
obo:PATO_0001604 a rdfs:Class ;
rdfs:label "decreased life span" ;
rdfs:comment "A life span which is relatively low." ;
rdfs:subClassOf obo:PATO_0000050 , obo:PATO_0002303 .
obo:WBPhenotype_0000452 a rdfs:Class ;
rdfs:label "tail protrusions" ;
rdfs:comment "Any irregular swelling in discrete regions of the tail, usually caused by a local defect in the normal smooth tapering of the hypodermis and/or cuticle (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000073 .
obo:WBPhenotype_0001618 a rdfs:Class ;
rdfs:label "halothane resistant" ;
rdfs:comment "Animals fail to respond to the concentration of the anesthetic halothane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000009 , obo:WBPhenotype_0001502 .
obo:WBPhenotype_0002284 a rdfs:Class ;
rdfs:label "head bend angle variant" ;
rdfs:comment "Any variation in the extent of the maximum flex of the most anterior portion of the animal compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001265 .
obo:GO_0051294 a rdfs:Class ;
rdfs:label "establishment of spindle orientation" ;
rdfs:comment "Any process that set the alignment of spindle relative to other cellular structures." ;
rdfs:subClassOf obo:GO_0051293 .
obo:WBPhenotype_0000459 a rdfs:Class ;
rdfs:label "pesticide response variant" ;
rdfs:comment "Animals exhibit variations in their response to any chemical substance that is used for killing pests, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:GO_0010821 a rdfs:Class ;
rdfs:label "regulation of mitochondrion organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:WBPhenotype_0001989 a rdfs:Class ;
rdfs:label "hypoxia hypersensitive" ;
rdfs:comment "Animals respond to hypoxic (low oxygen levels) stress after a shorter exposure time compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002423 .
obo:GO_0043227 a rdfs:Class ;
rdfs:label "membrane-bounded organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0043226 .
obo:WBPhenotype_0002594 a rdfs:Class ;
rdfs:label "long term plate tap habituation variant"@en ;
rdfs:comment "Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s)." ;
rdfs:subClassOf obo:WBPhenotype_0002469 , obo:WBPhenotype_0002599 .
obo:GO_0022611 a rdfs:Class ;
rdfs:label "dormancy process" ;
rdfs:comment "A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated." ;
rdfs:subClassOf obo:GO_0032502 .
obo:WBPhenotype_0001136 a rdfs:Class ;
rdfs:label "embryonic morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any of its parts during any developmental stage ranging from zygote formation to hatching compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000037 , obo:WBPhenotype_0002555 .
obo:WBPhenotype_0002363 a rdfs:Class ;
rdfs:label "cholesterol depletion resistant" ;
rdfs:comment "Animals are more resistant to the reduction of cholesterol in the environment compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000725 , obo:WBPhenotype_0002525 .
obo:WBPhenotype_0001179 a rdfs:Class ;
rdfs:label "obsolete No variantity scored" ;
rdfs:comment "OBSOLETE. Phenotypic examination of worms did not reveal an obvious abnormality compared with control animals." .
obo:CHEBI_17258 a rdfs:Class ;
rdfs:label "7H-purine" ;
rdfs:comment "The 7H-tautomer of purine." ;
rdfs:subClassOf obo:CHEBI_35584 .
obo:WBPhenotype_0000441 a rdfs:Class ;
rdfs:label "tail rounded" ;
rdfs:comment "Tails change shape and undergo retraction thereby forming a 'peloderan' or 'rounded' adult tail." ;
rdfs:subClassOf obo:WBPhenotype_0000073 .
obo:GO_1901076 a rdfs:Class ;
rdfs:label "positive regulation of engulfment of apoptotic cell" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell." ;
rdfs:subClassOf obo:GO_0060100 , obo:GO_0065007 , obo:GO_1901074 , obo:GO_2000427 .
obo:WBPhenotype_0001428 a rdfs:Class ;
rdfs:label "intestinal vacuole" ;
rdfs:comment "Vacuoles accumulate in the intestine." ;
rdfs:subClassOf obo:WBPhenotype_0000710 , obo:WBPhenotype_0002615 .
obo:GO_0003379 a rdfs:Class ;
rdfs:label "establishment of cell polarity involved in gastrulation cell migration" ;
rdfs:comment "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." ;
rdfs:subClassOf obo:GO_0003365 , obo:GO_0030010 .
obo:CHEBI_35469 a rdfs:Class ;
rdfs:label "antidepressant" ;
rdfs:comment "Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions." ;
rdfs:subClassOf obo:CHEBI_35471 .
obo:GO_0061025 a rdfs:Class ;
rdfs:label "membrane fusion" ;
rdfs:comment "The membrane organization process that joins two lipid bilayers to form a single membrane." ;
rdfs:subClassOf obo:GO_0061024 .
obo:WBPhenotype_0000098 a rdfs:Class ;
rdfs:label "pharyngeal intestinal valve development variant" ;
rdfs:comment "Any variation in the progression of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine over time compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000617 .
obo:WBPhenotype_0001902 a rdfs:Class ;
rdfs:label "fat associated body size increased" ;
rdfs:comment "Animals exhibit an increase in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining." ;
rdfs:subClassOf obo:WBPhenotype_0001901 .
obo:WBbt_0003732 a rdfs:Class ;
rdfs:label "terminal bulb" ;
rdfs:comment "the last, posterior bulb of the pharynx." ;
rdfs:subClassOf obo:WBbt_0005789 .
obo:GO_0050657 a rdfs:Class ;
rdfs:label "nucleic acid transport" ;
rdfs:comment "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0015931 .
obo:CHEBI_38824 a rdfs:Class ;
rdfs:label "fluorocarbon" ;
rdfs:comment "Compounds consisting wholly of fluorine and carbon." ;
rdfs:subClassOf obo:CHEBI_37143 .
obo:WBPhenotype_0001298 a rdfs:Class ;
rdfs:label "hindgut morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of the more posterior portion of the intestine, just anterior to the sphincter valve, which is subject to squeezing by the somatal-intestinal muscles compared to control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000710 .
obo:WBbt_0005332 a rdfs:Class ;
rdfs:label "body ganglion" ;
rdfs:comment "ganglion in the trunk of the body." ;
rdfs:subClassOf obo:WBbt_0005189 .
obo:GO_0007622 a rdfs:Class ;
rdfs:label "rhythmic behavior" ;
rdfs:comment "The specific behavior of an organism that recur with measured regularity." ;
rdfs:subClassOf obo:GO_0007610 .
obo:WBPhenotype_0002368 a rdfs:Class ;
rdfs:label "lysosomal refractile body accumulation" ;
rdfs:comment "Lysosomal refractile bodies are apoptotic-like cell corpse; however, they differ in size and shape and can be described as resembling irregular cell corpses. These bodies have been shown to represent enlarged lysosomes and can occur in conjunction with altered programmed cell death programs." ;
rdfs:subClassOf obo:WBPhenotype_0002562 .
obo:WBPhenotype_0001478 a rdfs:Class ;
rdfs:label "body elongation variant" ;
rdfs:comment "Any variation in the elongation of embryonic epidermal cells compared to control. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:CHEBI_26509 a rdfs:Class ;
rdfs:label "quinoline alkaloid" ;
rdfs:subClassOf obo:CHEBI_22315 .
obo:GO_0036493 a rdfs:Class ;
rdfs:label "positive regulation of translation in response to endoplasmic reticulum stress" ;
rdfs:comment "Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." ;
rdfs:subClassOf obo:GO_0032056 , obo:GO_0036490 , obo:GO_0065007 .
obo:CHEBI_33233 a rdfs:Class ;
rdfs:label "fundamental particle" ;
rdfs:comment "A particle not known to have substructure." ;
rdfs:subClassOf obo:CHEBI_36342 .
obo:WBPhenotype_0000628 a rdfs:Class ;
rdfs:label "spindle assembly defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ;
rdfs:subClassOf obo:WBPhenotype_0001102 , obo:WBPhenotype_0002415 .
obo:WBPhenotype_0000928 a rdfs:Class ;
rdfs:label "male physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required to carry out male-specific activities or to be able to perceive and respond to male-specific stimuli compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000889 .
obo:CHEBI_30362 a rdfs:Class ;
rdfs:label "isopentane" ;
rdfs:comment "An alkane that is butane substituted by a methyl group at position 2." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_18310 .
obo:GO_0061013 a rdfs:Class ;
rdfs:label "regulation of mRNA catabolic process" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0010468 , obo:GO_0065007 , obo:GO_1903311 .
obo:CHEBI_26712 a rdfs:Class ;
rdfs:label "sodium molecular entity" ;
rdfs:subClassOf obo:CHEBI_33296 .
obo:WBPhenotype_0004021 a rdfs:Class ;
rdfs:label "obsolete exaggerated body bends" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000481 a rdfs:Class ;
rdfs:label "negative chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of an animal in response to chemical repellants as defined by control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001434 .
obo:CHEBI_72600 a rdfs:Class ;
rdfs:label "spiroketal" ;
rdfs:comment "A cyclic ketal in which the ketal carbon is the only common atom of two rings." ;
rdfs:subClassOf obo:CHEBI_37948 , obo:CHEBI_59779 .
obo:WBPhenotype_0001565 a rdfs:Class ;
rdfs:label "lysine chemotaxis defective" ;
rdfs:comment "Failure to execute characteristic response to lysine as defined by control animals. In C. elegans, lysine is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001441 .
obo:GO_0010638 a rdfs:Class ;
rdfs:label "positive regulation of organelle organization" ;
rdfs:comment "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0051130 , obo:GO_0065007 .
obo:CHEBI_33663 a rdfs:Class ;
rdfs:label "cyclic hydrocarbon" ;
rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_33598 .
obo:CHEBI_37141 a rdfs:Class ;
rdfs:label "organobromine compound" ;
rdfs:comment "A compound containing at least one carbon-bromine bond." ;
rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_22928 .
obo:GO_0032058 a rdfs:Class ;
rdfs:label "positive regulation of translational initiation in response to stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0045948 , obo:GO_0065007 .
obo:WBPhenotype_0000492 a rdfs:Class ;
rdfs:label "corpus morphology defective" ;
rdfs:comment "Any variation in the form, structure or composition of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000709 .
obo:CHEBI_33597 a rdfs:Class ;
rdfs:label "homocyclic compound" ;
rdfs:comment "A cyclic compound having as ring members atoms of the same element only." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:CHEBI_63943 a rdfs:Class ;
rdfs:label "22,23-dihydroavermectin B1b" ;
rdfs:comment "A macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin." ;
rdfs:subClassOf obo:CHEBI_63944 , obo:CHEBI_72600 .
obo:WBPhenotype_0002583 a rdfs:Class ;
rdfs:label "miniature inhibitory post-synaptic current amplitude increased"@en ;
rdfs:comment "Animals exhibit increased amplitude of miniature inhibitory post-synaptic currents (mIPSC), compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002582 .
obo:CHEBI_35222 a rdfs:Class ;
rdfs:label "inhibitor" ;
rdfs:comment "A substance that diminishes the rate of a chemical reaction." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_33504 a rdfs:Class ;
rdfs:label "alkali metal cation" ;
rdfs:subClassOf obo:CHEBI_25213 .
obo:WBPhenotype_0001635 a rdfs:Class ;
rdfs:label "excess pharyngeal cells" ;
rdfs:comment "Animals contain an excess number of pharyngeal cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate." ;
rdfs:subClassOf obo:WBPhenotype_0000707 , obo:WBPhenotype_0002175 , obo:WBPhenotype_0002552 .
obo:WBPhenotype_0000028 a rdfs:Class ;
rdfs:label "RNA processing variant" ;
rdfs:comment "Variations in the processes involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:WBPhenotype_0001471 a rdfs:Class ;
rdfs:label "hexanol chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of hexanol. In C. elegans, at specific concentrations, hexanol is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0000265 .
obo:WBPhenotype_0000050 a rdfs:Class ;
rdfs:label "embryonic lethal" ;
rdfs:comment "Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." ;
rdfs:subClassOf obo:WBPhenotype_0000062 , obo:WBPhenotype_0000749 .
obo:WBPhenotype_0000147 a rdfs:Class ;
rdfs:label "organism starvation response variant" ;
rdfs:comment "Any variation in the state or activity of an organism as a result of deprivation of nourishment, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBls_0000807 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during 2-fold embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the 2-fold embryo life stage" ;
rdfs:subClassOf obo:WBls_0000805 .
obo:GO_0008219 a rdfs:Class ;
rdfs:label "cell death" ;
rdfs:comment "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_1903998 a rdfs:Class ;
rdfs:label "regulation of eating behavior" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of eating behavior." ;
rdfs:subClassOf obo:GO_0060259 , obo:GO_0065007 .
obo:WBbt_0005105 a rdfs:Class ;
rdfs:label "lateral ganglion" ;
rdfs:comment "The left and right lateral ganglia lie beside the nerve ring in the head. They each contain about (30) neuron cell bodies and send their neuronal processes into the ring at its posterior margin either laterally or ventrally via the amphid commissures and ventral ganglion, but form no local neuropil separate from the nerve ring. The lateral ganglia are in close contact with the lateral hypodermal cords." ;
rdfs:subClassOf obo:WBbt_0005135 .
obo:GO_0012505 a rdfs:Class ;
rdfs:label "endomembrane system" ;
rdfs:comment "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_37022 a rdfs:Class ;
rdfs:label "amino-acid anion" ;
rdfs:subClassOf obo:CHEBI_29067 , obo:CHEBI_35352 .
obo:GO_0009058 a rdfs:Class ;
rdfs:label "biosynthetic process" ;
rdfs:comment "A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0099143 a rdfs:Class ;
rdfs:label "presynaptic actin cytoskeleton" ;
rdfs:comment "The actin cytoskeleton that is part of a presynapse." ;
rdfs:subClassOf obo:GO_0015629 , obo:GO_0099569 .
obo:WBPhenotype_0000499 a rdfs:Class ;
rdfs:label "ethyl methanesulfonate response variant" ;
rdfs:comment "Animals exhibit variations in their response to ethyl methanesulfonate (EMS) compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBPhenotype_0001861 a rdfs:Class ;
rdfs:label "environmental stimuli induced gene expression variant" ;
rdfs:comment "Gene expression of an animal is not influenced by environmental changes in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:WBPhenotype_0000961 a rdfs:Class ;
rdfs:label "pattern of transgene expression variant" ;
rdfs:comment "Any variation in the cellular or subcellular pattern of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000111 , obo:WBPhenotype_0000306 .
obo:WBPhenotype_0000362 a rdfs:Class ;
rdfs:label "blastocoel variant" ;
rdfs:comment "Any variation in the progression of the fluid-filled compartment inside the developing embryo at the onset of gastrulation over time from its formation to its mature structure compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000047 .
obo:WBPhenotype_0002455 a rdfs:Class ;
rdfs:label "reduced recovery pumping response to light" ;
rdfs:comment "Animals exhibit a reduced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increasesto a lesser extent than in controls." ;
rdfs:subClassOf obo:WBPhenotype_0002453 .
obo:GO_1903422 a rdfs:Class ;
rdfs:label "negative regulation of synaptic vesicle recycling" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling." ;
rdfs:subClassOf obo:GO_0051051 , obo:GO_0065007 , obo:GO_1903421 .
obo:WBPhenotype_0000087 a rdfs:Class ;
rdfs:label "body wall cell development variant" ;
rdfs:comment "Any variation in the progression of a body wall muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000815 .
obo:GO_2000146 a rdfs:Class ;
rdfs:label "negative regulation of cell motility" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." ;
rdfs:subClassOf obo:GO_0040013 , obo:GO_0048523 , obo:GO_0065007 , obo:GO_2000145 .
obo:GO_0045137 a rdfs:Class ;
rdfs:label "development of primary sexual characteristics" ;
rdfs:comment "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." ;
rdfs:subClassOf obo:GO_0003006 .
obo:CHEBI_36342 a rdfs:Class ;
rdfs:label "subatomic particle" ;
rdfs:comment "A particle smaller than an atom." .
obo:WBPhenotype_0000972 a rdfs:Class ;
rdfs:label "neuronal sheath cell morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or composition of the glia-like support cell of neuronal sensilla that ensheathes the dendrite tips and or processes of neurons, from that observed in control animals. In C. elegans, sheath cells have highly invaginated and vesiculated surfaces, which provide a specialized environment for dendritic structures." ;
rdfs:subClassOf obo:WBPhenotype_0000899 , obo:WBPhenotype_0000969 , obo:WBPhenotype_0001528 .
obo:WBPhenotype_0001409 a rdfs:Class ;
rdfs:label "protein expression ectopic" ;
rdfs:comment "Any variation that results in the cellular expression of a protein in cells/tissues, that is otherwise not observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001408 .
obo:WBPhenotype_0000515 a rdfs:Class ;
rdfs:label "ventral nerve cord development variant" ;
rdfs:comment "Variations in any process whose specific outcome is the development and/or maintenance of the ventral nerve cord." ;
rdfs:subClassOf obo:WBPhenotype_0000945 .
obo:GO_0002832 a rdfs:Class ;
rdfs:label "negative regulation of response to biotic stimulus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." ;
rdfs:subClassOf obo:GO_0002831 , obo:GO_0048585 , obo:GO_0065007 .
obo:WBPhenotype_0001342 a rdfs:Class ;
rdfs:label "egg laying imipramine hypersensitive" ;
rdfs:comment "Animals respond to exogenous imipramine at a lower concentration or within a shorter time period than control animals under the same conditions." ;
rdfs:subClassOf obo:WBPhenotype_0001101 .
obo:GO_2000070 a rdfs:Class ;
rdfs:label "regulation of response to water deprivation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of response to water deprivation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080134 .
obo:WBPhenotype_0000419 a rdfs:Class ;
rdfs:label "L3 lethal" ;
rdfs:comment "Animals die at the L3 stage of the life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000058 , obo:WBPhenotype_0000116 .
obo:CHEBI_8116 a rdfs:Class ;
rdfs:label "phorbol" ;
rdfs:comment "A diterpenoid with the structure of tigliane hydroxylated at C-4, -9, -12(β), -13 and -20, with an oxo group at C-3 and unsaturation at the 1- and 6-positions." ;
rdfs:subClassOf obo:CHEBI_139592 , obo:CHEBI_3992 , obo:CHEBI_51689 , obo:CHEBI_52557 .
obo:WBPhenotype_0001312 a rdfs:Class ;
rdfs:label "neuron number variant" ;
rdfs:comment "The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000604 , obo:WBPhenotype_0002552 .
obo:CHEBI_33822 a rdfs:Class ;
rdfs:label "organic hydroxy compound" ;
rdfs:comment "An organic compound having at least one hydroxy group attached to a carbon atom." ;
rdfs:subClassOf obo:CHEBI_24651 , obo:CHEBI_50860 .
obo:GO_0098762 a rdfs:Class ;
rdfs:label "meiotic cell cycle phase" ;
rdfs:comment "One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ;
rdfs:subClassOf obo:GO_0022403 .
obo:GO_0009791 a rdfs:Class ;
rdfs:label "post-embryonic development" ;
rdfs:comment "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." ;
rdfs:subClassOf obo:GO_0032501 .
obo:WBPhenotype_0001439 a rdfs:Class ;
rdfs:label "anion positive chemotaxis defective" ;
rdfs:comment "Animals fail to move towards attractive anions." ;
rdfs:subClassOf obo:WBPhenotype_0001052 , obo:WBPhenotype_0001441 .
obo:CHEBI_35237 a rdfs:Class ;
rdfs:label "cysteine zwitterion" ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:GO_0007006 a rdfs:Class ;
rdfs:label "mitochondrial membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion." ;
rdfs:subClassOf obo:GO_0007005 , obo:GO_0061024 .
obo:WBPhenotype_0001489 a rdfs:Class ;
rdfs:label "gubernaculum morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or composition of the sclerotic cuticle that forms the roof of the proctodeum, from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001359 .
obo:GO_0006415 a rdfs:Class ;
rdfs:label "translational termination" ;
rdfs:comment "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)." ;
rdfs:subClassOf obo:GO_0032984 .
obo:WBPhenotype_0001849 a rdfs:Class ;
rdfs:label "zinc homeostasis variant" ;
rdfs:comment "Variations in the regulation of levels, transport, and metabolism of zinc ions within an organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002029 .
obo:GO_0009636 a rdfs:Class ;
rdfs:label "response to toxic substance" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." ;
rdfs:subClassOf obo:GO_0042221 .
obo:WBPhenotype_0001646 a rdfs:Class ;
rdfs:label "no pharynx" ;
rdfs:comment "Embryos fail to generate cells that exhibit pharyngeal specification." ;
rdfs:subClassOf obo:WBPhenotype_0000707 , obo:WBPhenotype_0002553 .
obo:CHEBI_33308 a rdfs:Class ;
rdfs:label "carboxylic ester" ;
rdfs:comment "An ester of a carboxylic acid, R1C(=O)OR2, where R1 = H or organyl and R2 = organyl." ;
rdfs:subClassOf obo:CHEBI_35701 , obo:CHEBI_36586 .
obo:WBPhenotype_0002006 a rdfs:Class ;
rdfs:label "anaphase I progression variant early embryo" ;
rdfs:comment "Compared to controls, embryos exhibit variations in the part meiosis I in which homologous chromosomes separate and migrate away from each other." ;
rdfs:subClassOf obo:WBPhenotype_0000775 , obo:WBPhenotype_0002389 .
obo:WBPhenotype_0002652 a rdfs:Class ;
rdfs:label "exopher production increased"@en ;
rdfs:comment "Cells exhibit a increase in production of exophers compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002651 .
obo:WBPhenotype_0000606 a rdfs:Class ;
rdfs:label "alimentary system physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the alimentary system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000575 .
obo:WBPhenotype_0001850 a rdfs:Class ;
rdfs:label "radiation induced germ cell apoptosis variant" ;
rdfs:comment "Programmed cell death of germ cells caused by exposure to ionizing energy does not occur to the same extent as it does in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000737 , obo:WBPhenotype_0002152 .
obo:GO_0048598 a rdfs:Class ;
rdfs:label "embryonic morphogenesis" ;
rdfs:comment "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_1900249 a rdfs:Class ;
rdfs:label "positive regulation of cytoplasmic translational elongation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation." ;
rdfs:subClassOf obo:GO_0045901 , obo:GO_0065007 , obo:GO_1900247 .
obo:GO_0030155 a rdfs:Class ;
rdfs:label "regulation of cell adhesion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0001460 a rdfs:Class ;
rdfs:label "ammonium chloride chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of ammonium chloride. In C. elegans, at specific concentrations, ammonium chloride is an attractant. NH4Cl has also been used to assay for Cl- attraction." ;
rdfs:subClassOf obo:WBPhenotype_0001047 .
obo:GO_2001223 a rdfs:Class ;
rdfs:label "negative regulation of neuron migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration." ;
rdfs:subClassOf obo:GO_0030336 , obo:GO_0065007 , obo:GO_2001222 .
obo:CHEBI_28765 a rdfs:Class ;
rdfs:label "phosphatidylinositol phosphate" ;
rdfs:comment "Any member of the phosphoinositide family of compounds, of which seven occur naturally." ;
rdfs:subClassOf obo:CHEBI_18179 .
obo:PATO_0002302 a rdfs:Class ;
rdfs:label "decreased process quality" ;
rdfs:comment "A quality of a process that has a value that is decreased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0001236 , obo:PATO_0002301 .
obo:PATO_0001296 a rdfs:Class ;
rdfs:label "luminous flux" ;
rdfs:comment "A scalar optical quality which obtains by the magnitude of the light emitted by the bearer." ;
rdfs:subClassOf obo:PATO_0001300 .
obo:PATO_0001163 a rdfs:Class ;
rdfs:label "decreased concentration" ;
rdfs:comment "A concentration which is lower relative to the normal or average." ;
rdfs:subClassOf obo:PATO_0001159 , obo:PATO_0001997 , obo:PATO_0002303 .
obo:CHEBI_38260 a rdfs:Class ;
rdfs:label "pyrrolidines" ;
rdfs:comment "Any of a class of heterocyclic amines having a saturated five-membered ring." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:WBbt_0005751 a rdfs:Class ;
rdfs:label "coelomocyte" ;
rdfs:comment "A free-floating spherical cell lying in the pseudocoelomic cavity of larvae and adult C. elegans which can endocytose many compounds, possibly for immune surveillance. There are six coelomocytes in adult hermaphrodites, and they display prominent cytoplasmic inclusions and vacuoles." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:CHEBI_23906 a rdfs:Class ;
rdfs:label "monoatomic cation" ;
rdfs:subClassOf obo:CHEBI_24867 , obo:CHEBI_36916 .
obo:WBPhenotype_0002181 a rdfs:Class ;
rdfs:label "extra excretory cells" ;
rdfs:comment "Animals produce an excess number of excretory cells compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000621 , obo:WBPhenotype_0002175 .
obo:GO_0032984 a rdfs:Class ;
rdfs:label "protein-containing complex disassembly" ;
rdfs:comment "The disaggregation of a protein-containing macromolecular complex into its constituent components." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0043933 .
obo:WBPhenotype_0000934 a rdfs:Class ;
rdfs:label "developmental morphology variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any of its parts during a given developmental stage compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000535 .
obo:GO_1905269 a rdfs:Class ;
rdfs:label "positive regulation of chromatin organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chromatin organization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902275 , obo:GO_2001252 .
obo:GO_0043068 a rdfs:Class ;
rdfs:label "positive regulation of programmed cell death" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0048522 , obo:GO_0065007 .
obo:WBPhenotype_0000128 a rdfs:Class ;
rdfs:label "temperature induced dauer formation increased" ;
rdfs:comment "Animals are more likely to form dauers at temperatures that do not induce dauer entry in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000639 .
obo:GO_1905153 a rdfs:Class ;
rdfs:label "regulation of membrane invagination" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of membrane invagination." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:CHEBI_38461 a rdfs:Class ;
rdfs:label "carbamate insecticide" ;
rdfs:comment "Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR1R2, where ROH is an alcohol, oxime, or phenol and R1 is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief." ;
rdfs:subClassOf obo:CHEBI_24852 , obo:CHEBI_38462 .
obo:WBPhenotype_0000474 a rdfs:Class ;
rdfs:label "muscle attachment variant" ;
rdfs:comment "Any variation in the connection of the cell(s) whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000622 .
obo:GO_0051147 a rdfs:Class ;
rdfs:label "regulation of muscle cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:WBPhenotype_0002444 a rdfs:Class ;
rdfs:label "pyrimidine biosynthesis variant" ;
rdfs:comment "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases." ;
rdfs:subClassOf obo:WBPhenotype_0000732 .
obo:GO_0022404 a rdfs:Class ;
rdfs:label "molting cycle process" ;
rdfs:comment "A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin." ;
rdfs:subClassOf obo:GO_0032501 .
obo:WBPhenotype_0000504 a rdfs:Class ;
rdfs:label "nuclear division variant" ;
rdfs:comment "Any variation in the process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0000002 a rdfs:Class ;
rdfs:label "kinker" ;
rdfs:comment "The animal moves or rests with uncharacteristic loss of smooth sinusoidal motion or body posture. Movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control animals." ;
rdfs:subClassOf obo:WBPhenotype_0004017 .
obo:WBPhenotype_0000723 a rdfs:Class ;
rdfs:label "obsolete cellular secretion abnormal" ;
rdfs:comment "OBSOLETE." .
obo:GO_1902436 a rdfs:Class ;
rdfs:label "negative regulation of male mating behavior" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior." ;
rdfs:subClassOf obo:GO_0048521 , obo:GO_0065007 , obo:GO_1902435 , obo:GO_2000242 .
obo:CHEBI_22632 a rdfs:Class ;
rdfs:label "arsenic molecular entity" ;
rdfs:subClassOf obo:CHEBI_33302 .
obo:GO_0051225 a rdfs:Class ;
rdfs:label "spindle assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ;
rdfs:subClassOf obo:GO_0007051 , obo:GO_0140694 .
obo:GO_0006261 a rdfs:Class ;
rdfs:label "DNA-templated DNA replication" ;
rdfs:comment "A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands." ;
rdfs:subClassOf obo:GO_0006260 .
obo:WBPhenotype_0002522 a rdfs:Class ;
rdfs:label "starvation-induced L1 arrest recovery abnormal"@en ;
rdfs:comment "Animals exhibit variations in the recovery from L1 larvae developmental arrest in response to a lack of food (starvation) available in the environment." ;
rdfs:subClassOf obo:WBPhenotype_0000751 .
obo:WBPhenotype_0001158 a rdfs:Class ;
rdfs:label "pronuclear breakdown asynchronous early emb" ;
rdfs:comment "Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001157 .
obo:WBPhenotype_0000383 a rdfs:Class ;
rdfs:label "lipid synthesis defective" ;
rdfs:comment "The de novo synthesis of any lipid species is reduced compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000725 .
obo:PATO_0001650 a rdfs:Class ;
rdfs:label "increased resistance to" ;
rdfs:comment "A resistance to a stimulus which is relatively high." ;
rdfs:subClassOf obo:PATO_0001178 , obo:PATO_0002305 .
obo:GO_0099523 a rdfs:Class ;
rdfs:label "presynaptic cytosol" ;
rdfs:comment "The region of the cytosol consisting of all cytosol that is part of the presynapse." ;
rdfs:subClassOf obo:GO_0005829 .
obo:WBPhenotype_0001579 a rdfs:Class ;
rdfs:label "cholinergic agonist hypersensitive" ;
rdfs:comment "Animals respond to a cholinergic agonist at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 .
obo:WBPhenotype_0000466 a rdfs:Class ;
rdfs:label "high oxygen hypersensitive" ;
rdfs:comment "Animals respond to hyperoxic (high oxygen tension) conditions after a shorter exposure time compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000464 .
obo:GO_1904410 a rdfs:Class ;
rdfs:label "negative regulation of secretory granule organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0065007 , obo:GO_1904409 .
obo:CHEBI_36043 a rdfs:Class ;
rdfs:label "antimicrobial drug" ;
rdfs:comment "A drug used to treat or prevent microbial infections." ;
rdfs:subClassOf obo:CHEBI_33281 , obo:CHEBI_35441 .
obo:GO_0006955 a rdfs:Class ;
rdfs:label "immune response" ;
rdfs:comment "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0050896 .
obo:WBPhenotype_0000651 a rdfs:Class ;
rdfs:label "constipated" ;
rdfs:comment "Animals exhibit delayed or infrequent passage and/or expulsion of fecal matter." ;
rdfs:subClassOf obo:WBPhenotype_0000650 .
obo:WBPhenotype_0000214 a rdfs:Class ;
rdfs:label "alpha amanitin hypersensitive" ;
rdfs:comment "Animals respond to alpha amanitin at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001323 a rdfs:Class ;
rdfs:label "vesicle morphology variant" ;
rdfs:comment "Animals display variations in the shape or size of their vesicles, which are spherical, membrane-bound fluid-filled organelles, compared to vesicles observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001671 .
obo:GO_2001251 a rdfs:Class ;
rdfs:label "negative regulation of chromosome organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0033044 , obo:GO_0065007 .
obo:GO_0090066 a rdfs:Class ;
rdfs:label "regulation of anatomical structure size" ;
rdfs:comment "Any process that modulates the size of an anatomical structure." ;
rdfs:subClassOf obo:GO_0065008 .
obo:WBbt_0006797 a rdfs:Class ;
rdfs:label "oocyte" ;
rdfs:comment "a female haploid germ cell." ;
rdfs:subClassOf obo:WBbt_0005758 , obo:WBbt_0006796 .
obo:CHEBI_63510 a rdfs:Class ;
rdfs:label "EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor" ;
rdfs:comment "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Na+/K+-transporting ATPase (EC 3.6.3.9)." ;
rdfs:subClassOf obo:CHEBI_76895 .
obo:CHEBI_48376 a rdfs:Class ;
rdfs:label "carbamimidic acid" ;
rdfs:subClassOf obo:CHEBI_48379 , obo:CHEBI_64708 .
obo:GO_0035694 a rdfs:Class ;
rdfs:label "mitochondrial protein catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure." ;
rdfs:subClassOf obo:GO_0030163 .
obo:CHEBI_59740 a rdfs:Class ;
rdfs:label "nucleophilic reagent" ;
rdfs:comment "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." ;
rdfs:subClassOf obo:CHEBI_33893 , obo:CHEBI_39144 .
obo:PATO_0001194 a rdfs:Class ;
rdfs:label "hyporesponsive to" ;
rdfs:comment "A response quality inhering in a bearer by virtue of the bearer's limited reaction to a stimulus or an agent." ;
rdfs:subClassOf obo:PATO_0000487 , obo:PATO_0002303 .
obo:WBPhenotype_0002154 a rdfs:Class ;
rdfs:label "polysome mRNA association variant" ;
rdfs:comment "The extent of mRNA ribosome associations varies from controls." ;
rdfs:subClassOf obo:WBPhenotype_0000121 , obo:WBPhenotype_0001371 .
obo:CHEBI_35555 a rdfs:Class ;
rdfs:label "mancude organic heteromonocyclic parent" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_35571 .
obo:GO_0007549 a rdfs:Class ;
rdfs:label "sex-chromosome dosage compensation" ;
rdfs:comment "Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes." ;
rdfs:subClassOf obo:GO_0040029 .
obo:WBPhenotype_0000318 a rdfs:Class ;
rdfs:label "cell cycle delayed" ;
rdfs:comment "Cells of the animals proceed through their replicative phase at a pace slower than observed for control cells." ;
rdfs:subClassOf obo:WBPhenotype_0000438 , obo:WBPhenotype_0001995 .
obo:GO_0048636 a rdfs:Class ;
rdfs:label "positive regulation of muscle organ development" ;
rdfs:comment "Any process that activates, maintains or increases the rate of muscle development." ;
rdfs:subClassOf obo:GO_0048634 , obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 .
obo:CHEBI_84729 a rdfs:Class ;
rdfs:label "hydroxyindoles" ;
rdfs:comment "Any member of the class of indoles carrying at least one hydroxy group." ;
rdfs:subClassOf obo:CHEBI_24828 , obo:CHEBI_33822 .
obo:WBPhenotype_0002569 a rdfs:Class ;
rdfs:label "hypodermis development variant"@en ;
rdfs:comment "Any variation in the progression of the hypodermis over time, from its formation to its mature state compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000701 .
obo:WBPhenotype_0000093 a rdfs:Class ;
rdfs:label "lineage variant" ;
rdfs:comment "The descendants of a particular precursor cell exhibit variations in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:CHEBI_59554 a rdfs:Class ;
rdfs:label "medium-chain fatty acid" ;
rdfs:comment "Any fatty acid with a chain length of between C6 and C12." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:GO_0009411 a rdfs:Class ;
rdfs:label "response to UV" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." ;
rdfs:subClassOf obo:GO_0009416 .
obo:WBPhenotype_0001234 a rdfs:Class ;
rdfs:label "nonanone chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to nonanone compared to control. In C. elegans, nonanone is a repellant." ;
rdfs:subClassOf obo:WBPhenotype_0001448 , obo:WBPhenotype_0001456 .
obo:WBPhenotype_0001978 a rdfs:Class ;
rdfs:label "germ cell partition absent" ;
rdfs:comment "Animals lack germ cell partitions (germ cell compartments)." ;
rdfs:subClassOf obo:WBPhenotype_0001977 .
obo:GO_0045834 a rdfs:Class ;
rdfs:label "positive regulation of lipid metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0019216 , obo:GO_0065007 .
obo:WBPhenotype_0000049 a rdfs:Class ;
rdfs:label "postembryonic development variant" ;
rdfs:comment "Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000531 .
obo:WBbt_0004534 a rdfs:Class ;
rdfs:label "excretory socket cell" ;
rdfs:comment "Excretory socket cell, links duct to hypodermis" ;
rdfs:subClassOf obo:WBbt_0005754 .
obo:WBPhenotype_0001495 a rdfs:Class ;
rdfs:label "cell division precocious" ;
rdfs:comment "Cells divide at an earlier stage of development compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000439 , obo:WBPhenotype_0000746 .
obo:GO_0005768 a rdfs:Class ;
rdfs:label "endosome" ;
rdfs:comment "A vacuole to which materials ingested by endocytosis are delivered." ;
rdfs:subClassOf obo:GO_0031410 .
obo:WBPhenotype_0002111 a rdfs:Class ;
rdfs:label "RME-1 recycling endosome localization variant" ;
rdfs:comment "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
rdfs:subClassOf obo:WBPhenotype_0002104 .
obo:PATO_0001857 a rdfs:Class ;
rdfs:label "concave" ;
rdfs:comment "A shape quality in a bearer by virtue of the bearer's curving inward." ;
rdfs:subClassOf obo:PATO_0002005 .
obo:GO_0060491 a rdfs:Class ;
rdfs:label "regulation of cell projection assembly" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of cell projection assembly." ;
rdfs:subClassOf obo:GO_0031344 , obo:GO_0044087 , obo:GO_0065007 .
obo:WBPhenotype_0000437 a rdfs:Class ;
rdfs:label "obsolete heterochronic defect" ;
rdfs:comment "OBSOLETE." .
obo:CHEBI_36894 a rdfs:Class ;
rdfs:label "elemental bromine" ;
rdfs:subClassOf obo:CHEBI_33434 .
obo:WBPhenotype_0001089 a rdfs:Class ;
rdfs:label "hexanol chemotaxis defective" ;
rdfs:comment "Failure to execute characteristic response to hexanol compared to control. In C. elegans, animals move towards typically attractive concentrations of hexanol." ;
rdfs:subClassOf obo:WBPhenotype_0001438 , obo:WBPhenotype_0001471 .
obo:CHEBI_24868 a rdfs:Class ;
rdfs:label "organic salt" ;
rdfs:subClassOf obo:CHEBI_24866 .
obo:WBPhenotype_0001417 a rdfs:Class ;
rdfs:label "organism desiccation response variant" ;
rdfs:comment "Any variation in the state or activity of an organism in response to extreme dryness or drought-like conditions, compared to control ." ;
rdfs:subClassOf obo:WBPhenotype_0000067 , obo:WBPhenotype_0000523 .
obo:WBPhenotype_0002121 a rdfs:Class ;
rdfs:label "heteroplasmy" ;
rdfs:comment "The presence of a mixture of more than one type of an organellar genome (mitochondrial DNA (mtDNA) or plastid DNA) within a cell or individual." ;
rdfs:subClassOf obo:WBPhenotype_0000576 .
obo:WBPhenotype_0002103 a rdfs:Class ;
rdfs:label "lysosome localization variant" ;
rdfs:comment "Any variation in the subcellular localization of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002098 .
obo:GO_1902749 a rdfs:Class ;
rdfs:label "regulation of cell cycle G2/M phase transition" ;
rdfs:comment "Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901987 .
obo:CHEBI_33303 a rdfs:Class ;
rdfs:label "chalcogen" ;
rdfs:comment "Any p-block element belonging to the group 16 family of the periodic table." ;
rdfs:subClassOf obo:CHEBI_33560 .
obo:WBPhenotype_0002633 a rdfs:Class ;
rdfs:label "pharynx ingressed"@en ;
rdfs:comment "Animals exhibit a pharynx that recedes into the animal's interior such that the animal cannot feed." ;
rdfs:subClassOf obo:WBPhenotype_0001748 .
obo:GO_0034613 a rdfs:Class .
obo:WBPhenotype_0000798 a rdfs:Class ;
rdfs:label "anterior body behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the head of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000795 .
obo:GO_2000816 a rdfs:Class ;
rdfs:label "negative regulation of mitotic sister chromatid separation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation." ;
rdfs:subClassOf obo:GO_0010965 , obo:GO_0033048 , obo:GO_0065007 , obo:GO_1905819 .
obo:WBPhenotype_0001487 a rdfs:Class ;
rdfs:label "male spicule development variant" ;
rdfs:comment "Animals exhibit variations in the development of the male elongated sclerotized structures covered by a hardened layer of cuticle in the tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000430 , obo:WBPhenotype_0000930 .
obo:CL_0000023 a rdfs:Class ;
rdfs:label "oocyte" ;
rdfs:comment "A female germ cell that has entered meiosis." ;
rdfs:subClassOf obo:CL_0000021 .
obo:GO_0045495 a rdfs:Class ;
rdfs:label "pole plasm" ;
rdfs:comment "Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo." ;
rdfs:subClassOf obo:GO_0005737 .
obo:WBls_0000075 a rdfs:Class ;
rdfs:label "worm life stage" ;
rdfs:comment "A developemental life stage of a worm" .
obo:CHEBI_30412 a rdfs:Class ;
rdfs:label "monoatomic dication" ;
rdfs:subClassOf obo:CHEBI_23906 .
obo:WBPhenotype_0000477 a rdfs:Class ;
rdfs:label "nucleolus refraction variant" ;
rdfs:comment "Any variation in the change in direction of a wave of light after passage through the nucleolus compared to control. The nucleolus is a small dense body in the nucleus." ;
rdfs:subClassOf obo:WBPhenotype_0000722 .
obo:WBPhenotype_0000839 a rdfs:Class ;
rdfs:label "Z1 hermaphrodite lineage variant" ;
rdfs:comment "Z1 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000837 .
obo:GO_1900121 a rdfs:Class ;
rdfs:label "negative regulation of receptor binding" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor." ;
rdfs:subClassOf obo:GO_0032091 , obo:GO_0065007 , obo:GO_1900120 .
obo:WBPhenotype_0000398 a rdfs:Class ;
rdfs:label "light body touch resistant" ;
rdfs:comment "Animals do not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000456 .
obo:WBPhenotype_0001872 a rdfs:Class ;
rdfs:label "drug induced locomotion variant" ;
rdfs:comment "Locomotion of the animal is not influenced by drug exposure in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:CHEBI_76759 a rdfs:Class ;
rdfs:label "EC 3.* (hydrolase) inhibitor" ;
rdfs:comment "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:GO_0010256 a rdfs:Class ;
rdfs:label "endomembrane system organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." ;
rdfs:subClassOf obo:GO_0016043 .
obo:CHEBI_134179 a rdfs:Class ;
rdfs:label "volatile organic compound" ;
rdfs:comment "Any organic compound having an initial boiling point less than or equal to 250 °C (482 °F) measured at a standard atmospheric pressure of 101.3 kPa." ;
rdfs:subClassOf obo:CHEBI_72695 .
obo:GO_2000199 a rdfs:Class ;
rdfs:label "positive regulation of ribonucleoprotein complex localization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0065007 , obo:GO_2000197 .
obo:GO_0001932 a rdfs:Class ;
rdfs:label "regulation of protein phosphorylation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein." ;
rdfs:subClassOf obo:GO_0031399 , obo:GO_0042325 , obo:GO_0065007 .
obo:GO_1901191 a rdfs:Class ;
rdfs:label "negative regulation of formation of translation initiation ternary complex" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex." ;
rdfs:subClassOf obo:GO_0031333 , obo:GO_0045947 , obo:GO_0065007 , obo:GO_1901190 .
obo:WBPhenotype_0000634 a rdfs:Class ;
rdfs:label "pharyngeal pumping variant" ;
rdfs:comment "Any variation in the contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002056 .
obo:GO_1901561 a rdfs:Class ;
rdfs:label "obsolete response to benomyl" ;
rdfs:comment "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus." .
obo:CHEBI_26833 a rdfs:Class ;
rdfs:label "sulfur atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25585 , obo:CHEBI_33303 .
obo:GO_0071840 a rdfs:Class ;
rdfs:label "cellular component organization or biogenesis" ;
rdfs:comment "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." ;
rdfs:subClassOf obo:GO_0009987 .
obo:PATO_0001929 a rdfs:Class ;
rdfs:label "variability of shape" ;
rdfs:comment "A variability quality inhering in a bearer by virtue of whether the bearer exhibits shape variation or change." ;
rdfs:subClassOf obo:PATO_0001303 .
obo:WBPhenotype_0001147 a rdfs:Class ;
rdfs:label "polar body defective early emb" ;
rdfs:comment "Polar bodies are abnormal in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001100 .
obo:GO_0032956 a rdfs:Class ;
rdfs:label "regulation of actin cytoskeleton organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ;
rdfs:subClassOf obo:GO_0032970 , obo:GO_0051493 , obo:GO_0065007 .
obo:WBPhenotype_0001913 a rdfs:Class ;
rdfs:label "excess coelomocytes" ;
rdfs:comment "The number of coelomocytes are increased compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds." ;
rdfs:subClassOf obo:WBPhenotype_0000618 , obo:WBPhenotype_0002175 .
obo:GO_1900244 a rdfs:Class ;
rdfs:label "positive regulation of synaptic vesicle endocytosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis." ;
rdfs:subClassOf obo:GO_0045807 , obo:GO_0065007 , obo:GO_1900242 , obo:GO_1903423 .
obo:CHEBI_76744 a rdfs:Class ;
rdfs:label "EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH2 (EC 1.17.*.*)." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:WBPhenotype_0000039 a rdfs:Class ;
rdfs:label "life span phenotype" ;
rdfs:comment "Adult life span is either longer or shorter than typical of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000576 , obo:WBPhenotype_0002555 .
obo:PATO_0001340 a rdfs:Class ;
rdfs:label "hermaphrodite" ;
rdfs:comment "A biological sex quality inhering in an organism or a population with both male and female sexual organs in one individual." ;
rdfs:subClassOf obo:PATO_0001894 .
obo:WBbt_0006770 a rdfs:Class ;
rdfs:label "P1" ;
rdfs:comment "The first (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1." ;
rdfs:subClassOf obo:WBbt_0008115 .
obo:WBbt_0005820 a rdfs:Class ;
rdfs:label "alimentary muscle" ;
rdfs:comment "muscle of the alimentary organ system." ;
rdfs:subClassOf obo:WBbt_0005780 .
obo:CHEBI_16382 a rdfs:Class ;
rdfs:label "iodide" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_16042 , obo:CHEBI_36897 .
obo:CHEBI_26399 a rdfs:Class ;
rdfs:label "purine ribonucleoside" ;
rdfs:comment "A ribonucleoside that has a purine moiety as the nucleobase (the R group in the illustration)." ;
rdfs:subClassOf obo:CHEBI_18254 , obo:CHEBI_26394 .
obo:WBls_0000023 a rdfs:Class ;
rdfs:label "larva Ce" ;
rdfs:comment "A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000105 , obo:WBls_0000817 .
obo:GO_0010770 a rdfs:Class ;
rdfs:label "positive regulation of cell morphogenesis" ;
rdfs:comment "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0022604 , obo:GO_0065007 .
obo:CHEBI_22695 a rdfs:Class ;
rdfs:label "base" ;
rdfs:comment "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Brønsted base) or with the vacant orbital of some other molecular entity (Lewis base)." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:GO_1902576 a rdfs:Class ;
rdfs:label "negative regulation of nuclear cell cycle DNA replication" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0033262 , obo:GO_0065007 , obo:GO_2000104 .
obo:CHEBI_38195 a rdfs:Class ;
rdfs:label "5beta-hydroxy steroid" ;
rdfs:subClassOf obo:CHEBI_136889 , obo:CHEBI_36848 .
obo:GO_1905820 a rdfs:Class ;
rdfs:label "positive regulation of chromosome separation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chromosome separation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090068 , obo:GO_1905818 .
obo:GO_0045992 a rdfs:Class ;
rdfs:label "negative regulation of embryonic development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." ;
rdfs:subClassOf obo:GO_0045995 , obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 .
obo:WBPhenotype_0000246 a rdfs:Class ;
rdfs:label "defecation cycle variable length" ;
rdfs:comment "Animals exhibit variation in the time of onset of the defecation motor program significantly greater than that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000207 .
obo:WBPhenotype_0000303 a rdfs:Class ;
rdfs:label "diacetyl chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to diacetyl as defined by control animals. In C.elegans diacetyl is typically attractive." ;
rdfs:subClassOf obo:WBPhenotype_0001438 , obo:WBPhenotype_0001470 .
obo:CHEBI_30772 a rdfs:Class ;
rdfs:label "butyric acid" ;
rdfs:comment "A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group." ;
rdfs:subClassOf obo:CHEBI_140601 , obo:CHEBI_39418 .
obo:WBPhenotype_0001331 a rdfs:Class ;
rdfs:label "motor neuron morphology variant" ;
rdfs:comment "Animals display variations in the structure or organization of components of the motor neuron, internal to the cell itself or in relation to the cellular environment compared to that observed in control animals. A motor neuron is a neuronal cell that synapses to an effector (muscle, gland etc.)." ;
rdfs:subClassOf obo:WBPhenotype_0000905 .
obo:WBPhenotype_0001808 a rdfs:Class ;
rdfs:label "cell corpse digestion variant" ;
rdfs:comment "The degradation of genomic and or cellular material of the corpse does not occur at the same rate or under the same conditions as observed in control animals undergoing cell death." ;
rdfs:subClassOf obo:WBPhenotype_0000885 .
obo:WBPhenotype_0000705 a rdfs:Class ;
rdfs:label "intestinal cell development variant" ;
rdfs:comment "Any variation in the progression of an intestinal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000529 , obo:WBPhenotype_0000708 .
obo:WBPhenotype_0000763 a rdfs:Class ;
rdfs:label "embryonic cell physiology variant" ;
rdfs:comment "Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for an embryonic cell to carry out its normal function and activities or be able to perceive and respond to stimuli." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:CHEBI_58951 a rdfs:Class ;
rdfs:label "short-chain fatty acid anion" ;
rdfs:comment "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6)." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:WBPhenotype_0001543 a rdfs:Class ;
rdfs:label "dauer reduced locomotion variant" ;
rdfs:comment "Dauer stage animals exhibit a decrease in self-propelled movement on a solid medium compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001001 .
obo:GO_0043523 a rdfs:Class ;
rdfs:label "regulation of neuron apoptotic process" ;
rdfs:comment "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:WBPhenotype_0000945 a rdfs:Class ;
rdfs:label "neuropil development variant" ;
rdfs:comment "Any variation in the progression of a dense feltwork of interwoven cytoplasmic processes of nerve cells (dendrites and axons) and support cells, over time from an initial condition to a later condition, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000623 .
obo:GO_0030037 a rdfs:Class ;
rdfs:label "obsolete actin filament reorganization involved in cell cycle" ;
rdfs:comment "OBSOLETE. The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs." .
obo:CHEBI_17968 a rdfs:Class ;
rdfs:label "butyrate" ;
rdfs:comment "A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_78115 .
obo:GO_0005622 a rdfs:Class ;
rdfs:label "intracellular anatomical structure" ;
rdfs:comment "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0000426 a rdfs:Class ;
rdfs:label "antibody staining increased" ;
rdfs:comment "Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000424 .
obo:WBPhenotype_0000686 a rdfs:Class ;
rdfs:label "organism ionizing radiation response variant" ;
rdfs:comment "Animals exhibit variations in their response ionizing radiation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:GO_0090257 a rdfs:Class ;
rdfs:label "regulation of muscle system process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." ;
rdfs:subClassOf obo:GO_0044057 , obo:GO_0065007 .
obo:GO_0043038 a rdfs:Class ;
rdfs:label "amino acid activation" ;
rdfs:comment "The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule." ;
rdfs:subClassOf obo:GO_0006520 .
obo:WBPhenotype_0000828 a rdfs:Class ;
rdfs:label "T lineages variant" ;
rdfs:comment "The descendants of TL or TR cells exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000825 .
obo:WBPhenotype_0002502 a rdfs:Class ;
rdfs:label "protein acetylation increased"@en ;
rdfs:comment "Animals exhibit an increase in the covalent addition of an acetyl group to one or more native amino acid side chains in proteins." ;
rdfs:subClassOf obo:WBPhenotype_0001917 .
obo:PATO_0001597 a rdfs:Class ;
rdfs:label "everted" ;
rdfs:comment "An oriented quality inhering in a bearer by virtue of the bearer's being turned outward in placement." ;
rdfs:subClassOf obo:PATO_0000614 .
obo:WBbt_0006929 a rdfs:Class ;
rdfs:label "sensillum" ;
rdfs:comment "sensory organ, consists of sensory neurons and supporting cells." ;
rdfs:subClassOf obo:WBbt_0003760 .
obo:CHEBI_37253 a rdfs:Class ;
rdfs:label "elemental zinc" ;
rdfs:subClassOf obo:CHEBI_27364 .
obo:GO_0051304 a rdfs:Class ;
rdfs:label "chromosome separation" ;
rdfs:comment "The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II)." ;
rdfs:subClassOf obo:GO_0022402 .
obo:WBPhenotype_0001939 a rdfs:Class ;
rdfs:label "bitter tastant response variant" ;
rdfs:comment "Animals are not repelled by bitter tastants such as quinine, primaquine quinacrine etc., to the same extent as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001450 .
obo:GO_1900181 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to nucleus" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900180 , obo:GO_1903828 .
obo:GO_0045841 a rdfs:Class ;
rdfs:label "negative regulation of mitotic metaphase/anaphase transition" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ;
rdfs:subClassOf obo:GO_0030071 , obo:GO_0045839 , obo:GO_0065007 , obo:GO_1901991 , obo:GO_1902100 , obo:GO_2000816 .
obo:WBPhenotype_0002295 a rdfs:Class ;
rdfs:label "body posture wavelength decreased" ;
rdfs:comment "Animals exhibit variations in body posture caused by a decrease in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal." ;
rdfs:subClassOf obo:WBPhenotype_0002294 .
obo:CHEBI_32458 a rdfs:Class ;
rdfs:label "cysteinium" ;
rdfs:subClassOf obo:CHEBI_33719 .
obo:WBPhenotype_0001236 a rdfs:Class ;
rdfs:label "transgene expression increased" ;
rdfs:comment "Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000962 .
obo:WBPhenotype_0001980 a rdfs:Class ;
rdfs:label "germ cell compartment expansion variant" ;
rdfs:comment "Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes)." ;
rdfs:subClassOf obo:WBPhenotype_0001969 .
obo:GO_0043524 a rdfs:Class ;
rdfs:label "negative regulation of neuron apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0043523 , obo:GO_0065007 .
obo:GO_0046831 a rdfs:Class ;
rdfs:label "regulation of RNA export from nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm." ;
rdfs:subClassOf obo:GO_0032239 , obo:GO_0046822 , obo:GO_0065007 .
obo:CHEBI_53000 a rdfs:Class ;
rdfs:label "epitope" ;
rdfs:comment "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CL_0000393 a rdfs:Class ;
rdfs:label "electrically responsive cell" ;
rdfs:comment "A cell whose function is determined by its response to an electric signal." ;
rdfs:subClassOf obo:CL_0000211 .
obo:WBPhenotype_0001710 a rdfs:Class ;
rdfs:label "rhythmic tolerance to osmotic stress variant" ;
rdfs:comment "Animals exhibit variations in light/dark cycle recurrence of reactions to osmotic stress compared to that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001709 .
obo:WBPhenotype_0000923 a rdfs:Class ;
rdfs:label "nonstriated muscle morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the nonstriated muscle compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000904 .
obo:GO_0022600 a rdfs:Class ;
rdfs:label "digestive system process" ;
rdfs:comment "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0003008 .
obo:WBPhenotype_0002660 a rdfs:Class ;
rdfs:label "germline stem cell depletion"@en ;
rdfs:comment "Animals exhibit a depletion of germline stem cells, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000684 .
obo:WBPhenotype_0001877 a rdfs:Class ;
rdfs:label "nuclear membrane morphology variant" ;
rdfs:comment "Any variation in the structure, form or composition of the membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002037 .
obo:GO_0000018 a rdfs:Class ;
rdfs:label "regulation of DNA recombination" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents." ;
rdfs:subClassOf obo:GO_0051052 , obo:GO_0065007 .
obo:GO_0033239 a rdfs:Class ;
rdfs:label "negative regulation of amine metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0033238 , obo:GO_0065007 .
obo:WBPhenotype_0000110 a rdfs:Class ;
rdfs:label "obsolete slightly dumpy" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000645 a rdfs:Class ;
rdfs:label "roller" ;
rdfs:comment "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern. In liquid media, wave propogation is helical rather than planar." ;
rdfs:subClassOf obo:WBPhenotype_0004017 .
obo:WBPhenotype_0000177 a rdfs:Class ;
rdfs:label "acetylcholinesterase reduced" ;
rdfs:comment "Any variation that results in a decrease of acetylcholine esterase levels, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000124 .
obo:WBPhenotype_0001100 a rdfs:Class ;
rdfs:label "early embryonic lethal" ;
rdfs:comment "Animal dies prior to the gastrulation stage of embryogenesis." ;
rdfs:subClassOf obo:WBPhenotype_0000050 .
obo:CHEBI_63367 a rdfs:Class ;
rdfs:label "monosaccharide derivative" ;
rdfs:comment "A carbohydrate derivative that is formally obtained from a monosaccharide." ;
rdfs:subClassOf obo:CHEBI_63299 .
obo:WBPhenotype_0000697 a rdfs:Class ;
rdfs:label "protruding vulva" ;
rdfs:comment "Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva." ;
rdfs:subClassOf obo:WBPhenotype_0000695 .
obo:WBPhenotype_0000166 a rdfs:Class ;
rdfs:label "seam cell fusion variant" ;
rdfs:comment "Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation." ;
rdfs:subClassOf obo:WBPhenotype_0000165 .
obo:GO_1901045 a rdfs:Class ;
rdfs:label "negative regulation of egg-laying behavior" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of oviposition." ;
rdfs:subClassOf obo:GO_0046662 , obo:GO_0048521 , obo:GO_0065007 , obo:GO_2000242 .
obo:WBPhenotype_0002374 a rdfs:Class ;
rdfs:label "RNAi transport defective" ;
rdfs:comment "Animals are deficient in the transport of silencing RNAs between cells during the systemic RNAi response process." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:CHEBI_76969 a rdfs:Class ;
rdfs:label "bacterial metabolite" ;
rdfs:comment "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." ;
rdfs:subClassOf obo:CHEBI_75787 .
obo:WBPhenotype_0000158 a rdfs:Class ;
rdfs:label "obsolete posterior body wall shortened interval" ;
rdfs:comment "OBSOLETE." .
obo:CHEBI_38700 a rdfs:Class ;
rdfs:label "organic sodium salt" ;
rdfs:subClassOf obo:CHEBI_24868 , obo:CHEBI_26714 .
obo:CHEBI_83399 a rdfs:Class ;
rdfs:label "marine xenobiotic metabolite" ;
rdfs:comment "Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms." ;
rdfs:subClassOf obo:CHEBI_76206 , obo:CHEBI_76507 .
obo:GO_0051648 a rdfs:Class ;
rdfs:label "vesicle localization" ;
rdfs:comment "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051640 .
obo:GO_0007059 a rdfs:Class ;
rdfs:label "chromosome segregation" ;
rdfs:comment "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." ;
rdfs:subClassOf obo:GO_0022402 .
obo:GO_1901610 a rdfs:Class ;
rdfs:label "positive regulation of vesicle transport along microtubule" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0065007 , obo:GO_1901608 .
obo:GO_0032064 a rdfs:Class ;
rdfs:label "positive regulation of translational initiation in response to osmotic stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ;
rdfs:subClassOf obo:GO_0032058 , obo:GO_0032062 , obo:GO_0043561 , obo:GO_0065007 .
obo:GO_0022613 a rdfs:Class ;
rdfs:label "ribonucleoprotein complex biogenesis" ;
rdfs:comment "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." ;
rdfs:subClassOf obo:GO_0044085 .
obo:WBPhenotype_0000257 a rdfs:Class ;
rdfs:label "phasmid neuron morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the phasmid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." ;
rdfs:subClassOf obo:WBPhenotype_0000255 .
obo:WBPhenotype_0000617 a rdfs:Class ;
rdfs:label "alimentary system development variant" ;
rdfs:comment "Any variation in the progression of the alimentary system over time, from its formation to its mature state compared to control. The alimentary system includes all the body structures involved in preparing food for absorption into the body and excretion of waste products." ;
rdfs:subClassOf obo:WBPhenotype_0000530 .
obo:CHEBI_65255 a rdfs:Class ;
rdfs:label "food preservative" ;
rdfs:comment "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." ;
rdfs:subClassOf obo:CHEBI_64047 .
obo:WBPhenotype_0002379 a rdfs:Class ;
rdfs:label "mitochondria localization variant" ;
rdfs:comment "The subcellular localization of mitochondrial organelles differ from that observed in control cells." ;
rdfs:subClassOf obo:WBPhenotype_0002098 .
obo:WBPhenotype_0002218 a rdfs:Class ;
rdfs:label "arsenite hypersensitive" ;
rdfs:comment "Animals respond to arsenite at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001918 .
obo:GO_0010288 a rdfs:Class ;
rdfs:label "response to lead ion" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus." ;
rdfs:subClassOf obo:GO_0010038 .
obo:CHEBI_35776 a rdfs:Class ;
rdfs:label "arsenic oxoanion" ;
rdfs:subClassOf obo:CHEBI_22632 , obo:CHEBI_33459 .
obo:CHEBI_25375 a rdfs:Class ;
rdfs:label "monoamine molecular messenger" ;
rdfs:comment "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (‒CH2‒CH2‒). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." ;
rdfs:subClassOf obo:CHEBI_63534 .
obo:CHEBI_26710 a rdfs:Class ;
rdfs:label "sodium chloride" ;
rdfs:comment "An inorganic chloride salt having sodium(1+) as the counterion." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_36093 , obo:CHEBI_38702 .
obo:WBPhenotype_0002337 a rdfs:Class ;
rdfs:label "path curvature decreased" ;
rdfs:comment "Animals exhibit decreases in the extent to which the overall path of movement is curved, producing shallower, less frequent curves and an overall straighter path, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002335 .
obo:GO_0043277 a rdfs:Class ;
rdfs:label "apoptotic cell clearance" ;
rdfs:comment "The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte." ;
rdfs:subClassOf obo:GO_0006909 .
obo:GO_0008380 a rdfs:Class ;
rdfs:label "RNA splicing" ;
rdfs:comment "The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." ;
rdfs:subClassOf obo:GO_0006396 .
obo:GO_0051293 a rdfs:Class ;
rdfs:label "establishment of spindle localization" ;
rdfs:comment "The directed movement of the spindle to a specific location in the cell." ;
rdfs:subClassOf obo:GO_0000226 , obo:GO_0051649 , obo:GO_0051653 , obo:GO_0051656 .
obo:CHEBI_37868 a rdfs:Class ;
rdfs:label "octanol" ;
rdfs:comment "A fatty alcohol consisting of a hydroxy function at any position of an unbranched saturated chain of eight carbon atoms." ;
rdfs:subClassOf obo:CHEBI_134179 , obo:CHEBI_197506 , obo:CHEBI_50584 .
obo:GO_0000932 a rdfs:Class ;
rdfs:label "P-body" ;
rdfs:comment "A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing." ;
rdfs:subClassOf obo:GO_0036464 .
obo:WBPhenotype_0002557 a rdfs:Class ;
rdfs:label "body region phenotype"@en ;
rdfs:comment "A phenotype affecting a particular body region." ;
rdfs:subClassOf obo:WBPhenotype_0002551 .
obo:CHEBI_4290 a rdfs:Class ;
rdfs:label "1,1-dimethyl-4-phenylpiperazinium iodide" ;
rdfs:subClassOf obo:CHEBI_35273 , obo:CHEBI_46848 , obo:CHEBI_46849 , obo:CHEBI_50356 .
obo:WBPhenotype_0000731 a rdfs:Class ;
rdfs:label "germ cell hypersensitive ionizing radiation" ;
rdfs:comment "Germ cells exhibit increased sensitivity to the effects of ion producing radiation compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000712 .
obo:GO_0000962 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial RNA catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ;
rdfs:subClassOf obo:GO_0000960 , obo:GO_0009896 , obo:GO_0051254 , obo:GO_0065007 .
obo:GO_0099504 a rdfs:Class ;
rdfs:label "synaptic vesicle cycle" ;
rdfs:comment "A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters." ;
rdfs:subClassOf obo:GO_0051649 , obo:GO_0099003 .
obo:WBPhenotype_0001348 a rdfs:Class ;
rdfs:label "chromosome morphology variant" ;
rdfs:comment "Variations in the form or composition of a structure in the cell nucleus which contains the genetic material encoded as DNA and surrounded by histone proteins and other regulatory elements compared to control. In C. elegans the normal cell contains 5 pairs of 'autosomes' and one or two X chromosomes (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001028 .
obo:GO_0007049 a rdfs:Class ;
rdfs:label "cell cycle" ;
rdfs:comment "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." ;
rdfs:subClassOf obo:GO_0009987 .
obo:PATO_0001624 a rdfs:Class ;
rdfs:label "decreased functionality" ;
rdfs:comment "A functionality quality held by the bearer when the latter exhibits decreased ability to perform a regular function(s)." ;
rdfs:subClassOf obo:PATO_0001510 , obo:PATO_0002303 .
obo:GO_0003990 a rdfs:Class ;
rdfs:label "acetylcholinesterase activity" ;
rdfs:comment "Catalysis of the reaction: acetylcholine + H2O = choline + acetate." ;
rdfs:subClassOf obo:GO_0004104 .
obo:GO_0044703 a rdfs:Class ;
rdfs:label "multi-organism reproductive process" ;
rdfs:comment "A biological process that directly contributes to the process of producing new individuals, involving another organism." ;
rdfs:subClassOf obo:GO_0022414 .
obo:WBPhenotype_0000443 a rdfs:Class ;
rdfs:label "spicule morphology variant" ;
rdfs:comment "Any variation in the appearance of the elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001024 .
obo:GO_0001934 a rdfs:Class ;
rdfs:label "positive regulation of protein phosphorylation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein." ;
rdfs:subClassOf obo:GO_0001932 , obo:GO_0031401 , obo:GO_0042327 , obo:GO_0065007 .
obo:CHEBI_36829 a rdfs:Class ;
rdfs:label "polyatomic monoanion" ;
rdfs:subClassOf obo:CHEBI_33273 , obo:CHEBI_36830 .
obo:PATO_0000587 a rdfs:Class ;
rdfs:label "decreased size" ;
rdfs:comment "A size quality which is relatively low." ;
rdfs:subClassOf obo:PATO_0000117 , obo:PATO_0002303 .
obo:WBls_0000026 a rdfs:Class ;
rdfs:label "L1-L2 molt Ce" ;
rdfs:comment "The stage when an animal shifts from L1 larva to L2 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000824 .
obo:WBbt_0004458 a rdfs:Class ;
rdfs:label "MS" ;
rdfs:comment "Embryonic founder cell" ;
rdfs:subClassOf obo:WBbt_0007028 .
obo:WBPhenotype_0000813 a rdfs:Class ;
rdfs:label "gland cell development variant" ;
rdfs:comment "Any variation in the progression of a gland cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:PATO_0001435 a rdfs:Class ;
rdfs:label "attachment quality" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer's having connection or association with another entity." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:CHEBI_142355 a rdfs:Class ;
rdfs:label "purines D-ribonucleoside" ;
rdfs:comment "A purine ribonucleoside that is a purine derivative attached to a β-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage." ;
rdfs:subClassOf obo:CHEBI_26399 .
obo:WBPhenotype_0002524 a rdfs:Class ;
rdfs:label "molybdenum cofactor depletion hypersensitive"@en ;
rdfs:comment "Animals are more sensitive to the depletion of molybdenum cofactor from the diet compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002526 .
obo:WBPhenotype_0000408 a rdfs:Class ;
rdfs:label "dauer recovery inhibited" ;
rdfs:comment "The process through which a dauer larva reverts to normal developmental programs is blocked." ;
rdfs:subClassOf obo:WBPhenotype_0000127 .
obo:WBPhenotype_0000244 a rdfs:Class ;
rdfs:label "apoptotic arrest" ;
rdfs:comment "Cells fail to complete the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes." ;
rdfs:subClassOf obo:WBPhenotype_0000182 .
obo:CHEBI_16708 a rdfs:Class ;
rdfs:label "adenine" ;
rdfs:comment "The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_20706 , obo:CHEBI_26386 .
obo:GO_0006950 a rdfs:Class ;
rdfs:label "response to stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0050896 .
obo:WBPhenotype_0000627 a rdfs:Class ;
rdfs:label "anesthetic response variant" ;
rdfs:comment "Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0000299 a rdfs:Class ;
rdfs:label "sensillum morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000604 , obo:WBPhenotype_0002553 .
obo:CHEBI_59905 a rdfs:Class ;
rdfs:label "dopaminium(1+)" ;
rdfs:comment "An ammonium ion that is the conjugate acid of dopamine; major species at pH 7.3." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35274 .
obo:WBPhenotype_0001834 a rdfs:Class ;
rdfs:label "mRNA splicing variant" ;
rdfs:comment "Variations in the processes regulating the excision of intervening introns from the primary mRNA transcript, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000028 , obo:WBPhenotype_0001827 .
obo:PATO_0000467 a rdfs:Class ;
rdfs:label "present" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's existence." ;
rdfs:subClassOf obo:PATO_0000070 .
obo:WBPhenotype_0000772 a rdfs:Class ;
rdfs:label "sister chromatid segregation defective early emb" ;
rdfs:comment "Daughter nuclei are deformed and stay close to central cortex, cytokinesis defects." ;
rdfs:subClassOf obo:WBPhenotype_0000773 , obo:WBPhenotype_0001078 .
obo:WBPhenotype_0001748 a rdfs:Class ;
rdfs:label "pharynx unattached" ;
rdfs:comment "The pharynx or pharyngeal muscle does not form a functional connection to the mouth or buccal cavity." ;
rdfs:subClassOf obo:WBPhenotype_0000707 .
obo:CHEBI_24834 a rdfs:Class ;
rdfs:label "inorganic anion" ;
rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_36914 .
obo:CHEBI_52855 a rdfs:Class ;
rdfs:label "inorganic nanoparticle" ;
rdfs:comment "A nanoparticle that contains no carbon." ;
rdfs:subClassOf obo:CHEBI_50803 .
obo:WBPhenotype_0002058 a rdfs:Class ;
rdfs:label "pore forming toxin response variant" ;
rdfs:comment "Animals are not affected to the same degree as control animals under similar conditions of pore forming toxin exposure." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:IAO_0000102 a rdfs:Class ;
rdfs:label "data about an ontology part"@en ;
rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
rdfs:subClassOf obo:IAO_0000027 .
obo:WBPhenotype_0001517 a rdfs:Class ;
rdfs:label "annulae morphology variant" ;
rdfs:comment "Animals exhibit variations in the circumferential pattern of ridges in the outer cortical layer of the cuticle, compared to that observed in control animals of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0000948 , obo:WBPhenotype_0002089 .
obo:GO_0050807 a rdfs:Class ;
rdfs:label "regulation of synapse organization" ;
rdfs:comment "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:WBPhenotype_0001119 a rdfs:Class ;
rdfs:label "cell cycle slow early emb" ;
rdfs:comment "Embryos take longer to divide during the first and second cell divisions." ;
rdfs:subClassOf obo:WBPhenotype_0000438 , obo:WBPhenotype_0001116 .
obo:WBPhenotype_0002343 a rdfs:Class ;
rdfs:label "bent posture decreased" ;
rdfs:comment "Animals exhibit decreased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends." ;
rdfs:subClassOf obo:WBPhenotype_0002341 .
obo:GO_0033043 a rdfs:Class ;
rdfs:label "regulation of organelle organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:GO_1902846 a rdfs:Class ;
rdfs:label "positive regulation of mitotic spindle elongation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation." ;
rdfs:subClassOf obo:GO_0032888 , obo:GO_0062033 , obo:GO_0065007 .
obo:WBPhenotype_0000029 a rdfs:Class ;
rdfs:label "systemic RNAi variant" ;
rdfs:comment "Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:WBbt_0005729 a rdfs:Class ;
rdfs:label "Tissue" ;
rdfs:comment "Association of cells with a common embryological origin or pathway and similar structure and function. Usually, cells of a tissue are contiguous at cell membranes and may be of one or more types. Tissues aggregate to form organs." ;
rdfs:subClassOf obo:WBbt_0005763 .
obo:WBPhenotype_0001681 a rdfs:Class ;
rdfs:label "spindle orientation variant" ;
rdfs:comment "The alignment of the spindle relative to other cellular structures varies from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002414 .
obo:WBPhenotype_0000497 a rdfs:Class ;
rdfs:label "organism gamma ray response variant" ;
rdfs:comment "Animals exhibit variations in their response to gamma ray radiation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000686 .
obo:WBPhenotype_0001957 a rdfs:Class ;
rdfs:label "gonad small" ;
rdfs:comment "A decrease in size of the specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001355 .
obo:GO_0033260 a rdfs:Class ;
rdfs:label "nuclear DNA replication" ;
rdfs:comment "The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." ;
rdfs:subClassOf obo:GO_0006260 , obo:GO_0044786 .
obo:GO_0051078 a rdfs:Class ;
rdfs:label "meiotic nuclear membrane disassembly" ;
rdfs:comment "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs." ;
rdfs:subClassOf obo:GO_0051081 , obo:GO_1903046 .
obo:WBPhenotype_0000363 a rdfs:Class ;
rdfs:label "cell division slow" ;
rdfs:comment "Any variation that delays the physical partitioning and separation of a cell into daughter cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000438 , obo:WBPhenotype_0000746 .
obo:WBPhenotype_0001196 a rdfs:Class ;
rdfs:label "synchronization calcium signal defective pharynx" ;
rdfs:comment "Calcium spikes lack synchrony in the musculature of the corpus and the terminal bulb as seen in control." ;
rdfs:subClassOf obo:WBPhenotype_0001192 .
obo:WBbt_0005843 a rdfs:Class ;
rdfs:label "eggshell" ;
rdfs:comment "The shell or external calcareous covering of an egg" ;
rdfs:subClassOf obo:WBbt_0005732 .
obo:CHEBI_35610 a rdfs:Class ;
rdfs:label "antineoplastic agent" ;
rdfs:comment "A substance that inhibits or prevents the proliferation of neoplasms." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:CHEBI_90710 a rdfs:Class ;
rdfs:label "receptor modulator" ;
rdfs:comment "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:WBPhenotype_0002584 a rdfs:Class ;
rdfs:label "bisphenol A resistant"@en ;
rdfs:comment "Animals survive longer, or do not respond to the same degree as control animals under similar conditions of bisphenol A exposure." ;
rdfs:subClassOf obo:WBPhenotype_0000931 .
obo:CHEBI_57299 a rdfs:Class ;
rdfs:label "ATP(3-)" ;
rdfs:comment "A ribonucleoside triphosphate oxoanion that is the trianion of adenosine 5'-triphosphate arising from deprotonation of three of the four free triphosphate OH groups." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_59724 .
obo:WBPhenotype_0000684 a rdfs:Class ;
rdfs:label "fewer germ cells" ;
rdfs:comment "Germ cell populations are reduced compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000823 , obo:WBPhenotype_0002174 , obo:WBPhenotype_0002552 .
obo:PATO_0001997 a rdfs:Class ;
rdfs:label "decreased amount" ;
rdfs:comment "An amount which is relatively low." ;
rdfs:subClassOf obo:PATO_0000070 , obo:PATO_0000467 , obo:PATO_0002301 .
obo:GO_0141188 a rdfs:Class ;
rdfs:label "nucleic acid catabolic process" ;
rdfs:comment "The cellular DNA metabolic process resulting in the breakdown of a nucleic acid." ;
rdfs:subClassOf obo:GO_0009057 , obo:GO_0034655 , obo:GO_0090304 .
obo:GO_1902292 a rdfs:Class ;
rdfs:label "cell cycle DNA replication initiation" ;
rdfs:comment "Any DNA replication initiation that is involved in cell cycle DNA replication." ;
rdfs:subClassOf obo:GO_0006270 , obo:GO_0022402 .
obo:GO_0032939 a rdfs:Class ;
rdfs:label "positive regulation of translation in response to oxidative stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0032056 , obo:GO_0065007 .
obo:WBbt_0005501 a rdfs:Class ;
rdfs:label "outer labial sensillum" ;
rdfs:subClassOf obo:WBbt_0005107 .
obo:WBPhenotype_0002666 a rdfs:Class ;
rdfs:label "abnormal dissolution of RNA condensate"@en ;
rdfs:comment "An abnormal dissolution of an RNA condensate within a cell or cellular compartment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002665 .
obo:GO_0071709 a rdfs:Class ;
rdfs:label "membrane assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a membrane." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0061024 .
obo:WBPhenotype_0000086 a rdfs:Class ;
rdfs:label "shrunken intestine" ;
rdfs:comment "Intestine is shrunken and may appear constricted." ;
rdfs:subClassOf obo:WBPhenotype_0000710 .
obo:PATO_0000186 a rdfs:Class ;
rdfs:label "behavioral quality" ;
rdfs:comment "An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:CHEBI_26708 a rdfs:Class ;
rdfs:label "sodium atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_22314 .
obo:WBls_0000102 a rdfs:Class ;
rdfs:label "nematode embryo" ;
rdfs:comment "The whole period of embryogenesis in a nematode, from the formation of an egg until hatching." ;
rdfs:subClassOf obo:WBls_0000101 .
obo:CHEBI_29340 a rdfs:Class ;
rdfs:label "hydridonitrate(2-)" ;
rdfs:comment "A divalent inorganic anion resulting from the removal of two protons from ammonia." ;
rdfs:subClassOf obo:CHEBI_35106 , obo:CHEBI_79388 .
obo:WBPhenotype_0000329 a rdfs:Class ;
rdfs:label "pumping asynchronous" ;
rdfs:comment "The rhythmic contractions of pharyngeal compartments are no longer synchronized compared to control. In C. elegans the corpus and terminal bulb normally contract simultaneously." ;
rdfs:subClassOf obo:WBPhenotype_0001006 .
obo:GO_0034976 a rdfs:Class ;
rdfs:label "response to endoplasmic reticulum stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." ;
rdfs:subClassOf obo:GO_0033554 .
obo:CHEBI_23480 a rdfs:Class ;
rdfs:label "cyclohexanols" ;
rdfs:comment "An alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:GO_1905637 a rdfs:Class ;
rdfs:label "regulation of mitochondrial mRNA catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process." ;
rdfs:subClassOf obo:GO_0000960 , obo:GO_0061013 , obo:GO_0065007 .
obo:GO_0060631 a rdfs:Class ;
rdfs:label "regulation of meiosis I" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ;
rdfs:subClassOf obo:GO_0040020 , obo:GO_0065007 .
obo:GO_0016757 a rdfs:Class ;
rdfs:label "glycosyltransferase activity" ;
rdfs:comment "Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor)." ;
rdfs:subClassOf obo:GO_0016740 .
obo:GO_2000045 a rdfs:Class ;
rdfs:label "regulation of G1/S transition of mitotic cell cycle" ;
rdfs:comment "Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901990 , obo:GO_1902806 .
obo:CHEBI_33362 a rdfs:Class ;
rdfs:label "nickel group element atom" ;
rdfs:subClassOf obo:CHEBI_33561 .
obo:GO_0048284 a rdfs:Class ;
rdfs:label "organelle fusion" ;
rdfs:comment "The creation of a single organelle from two or more organelles." ;
rdfs:subClassOf obo:GO_0006996 .
obo:GO_0051081 a rdfs:Class ;
rdfs:label "nuclear membrane disassembly" ;
rdfs:comment "The controlled breakdown of the nuclear membranes, for example during cellular division." ;
rdfs:subClassOf obo:GO_0030397 , obo:GO_0071763 .
obo:WBPhenotype_0000512 a rdfs:Class ;
rdfs:label "VNC nuclear positioning variant" ;
rdfs:comment "Variations in spacing or location were observed between adjacent ventral cord nuclei or between ventral cord nuclei and another nucleus used as a reference point. In C. elegans, these nuclei are distributed equally and predictably, such that they can be unambiguously distinguished by their position." ;
rdfs:subClassOf obo:WBPhenotype_0000511 .
obo:CHEBI_37962 a rdfs:Class ;
rdfs:label "adrenergic agent" ;
rdfs:comment "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." ;
rdfs:subClassOf obo:CHEBI_35942 .
obo:WBPhenotype_0000885 a rdfs:Class ;
rdfs:label "engulfment variant" ;
rdfs:comment "Any variation in the removal of a cell corpse, by a neighboring cell or a phagocyte compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:GO_0032259 a rdfs:Class ;
rdfs:label "methylation" ;
rdfs:comment "The process in which a methyl group is covalently attached to a molecule." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0031128 a rdfs:Class ;
rdfs:label "developmental induction" ;
rdfs:comment "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." ;
rdfs:subClassOf obo:GO_0032502 .
obo:GO_0006405 a rdfs:Class ;
rdfs:label "RNA export from nucleus" ;
rdfs:comment "The directed movement of RNA from the nucleus to the cytoplasm." ;
rdfs:subClassOf obo:GO_0050658 , obo:GO_0051168 .
obo:WBbt_0007028 a rdfs:Class ;
rdfs:label "embryonic cell" ;
rdfs:comment "cell that exists in and is part of an embryo." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:CHEBI_35875 a rdfs:Class ;
rdfs:label "imidazopyrimidine" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_33833 , obo:CHEBI_38101 .
obo:GO_0034608 a rdfs:Class ;
rdfs:label "vulval location" ;
rdfs:comment "Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate." ;
rdfs:subClassOf obo:GO_0060179 .
obo:WBPhenotype_0002590 a rdfs:Class ;
rdfs:label "linker cell detached"@en ;
rdfs:comment "The linker cell of male animals becomes detached from the rest of the male gonad." ;
rdfs:subClassOf obo:WBPhenotype_0001675 .
obo:GO_0007338 a rdfs:Class ;
rdfs:label "single fertilization" ;
rdfs:comment "The union of male and female gametes to form a zygote." ;
rdfs:subClassOf obo:GO_0009566 .
obo:WBPhenotype_0001389 a rdfs:Class ;
rdfs:label "cell gamma ray resistant" ;
rdfs:comment "Cells fail to respond to the dosage of gamma irradiation that elicits a response in control animals. Alternatively, cells require longer exposure times to gamma irradiation to mimic the response observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001326 .
obo:GO_0043555 a rdfs:Class ;
rdfs:label "regulation of translation in response to stress" ;
rdfs:comment "Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:GO_0065010 a rdfs:Class ;
rdfs:label "extracellular membrane-bounded organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." ;
rdfs:subClassOf obo:GO_0043227 , obo:GO_0043230 .
obo:WBPhenotype_0000761 a rdfs:Class ;
rdfs:label "spindle position orientation defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the placement or the alignment of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ;
rdfs:subClassOf obo:WBPhenotype_0001102 .
obo:CHEBI_24860 a rdfs:Class ;
rdfs:label "iodine molecular entity" ;
rdfs:subClassOf obo:CHEBI_24471 .
obo:PATO_0000595 a rdfs:Class ;
rdfs:label "increased volume" ;
rdfs:comment "A volume which is relatively high." ;
rdfs:subClassOf obo:PATO_0000586 , obo:PATO_0000918 .
obo:GO_0030154 a rdfs:Class ;
rdfs:label "cell differentiation" ;
rdfs:comment "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." ;
rdfs:subClassOf obo:GO_0048869 .
obo:WBPhenotype_0001156 a rdfs:Class ;
rdfs:label "pronuclear size defective early emb" ;
rdfs:comment "Maternal or paternal pronucleus is either too small or too large." ;
rdfs:subClassOf obo:WBPhenotype_0001026 , obo:WBPhenotype_0001159 .
obo:WBPhenotype_0001885 a rdfs:Class ;
rdfs:label "cleavage furrow initiation defective early emb" ;
rdfs:comment "Embryos exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ;
rdfs:subClassOf obo:WBPhenotype_0001129 .
obo:GO_0099569 a rdfs:Class ;
rdfs:label "presynaptic cytoskeleton" ;
rdfs:comment "The portion of the cytoskeleton contained within the presynapse." ;
rdfs:subClassOf obo:GO_0005856 .
obo:WBPhenotype_0002354 a rdfs:Class ;
rdfs:label "increased susceptibility to fungal infection" ;
rdfs:comment "Animals are more prone to infection from fungal pathogens compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001013 .
obo:GO_0030425 a rdfs:Class ;
rdfs:label "dendrite" ;
rdfs:comment "A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body." ;
rdfs:subClassOf obo:GO_0043005 .
obo:WBPhenotype_0001776 a rdfs:Class ;
rdfs:label "siRNA expression variant" ;
rdfs:comment "Variations in the biogenesis and stability of the small interfering class of RNA molecules compared to control. In C. elegans these molecules are antisense to mRNA's and may be processed from long double-stranded RNA." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:WBPhenotype_0000008 a rdfs:Class ;
rdfs:label "anesthetic hypersensitive" ;
rdfs:comment "Animals respond to anesthetic at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0000627 .
obo:CHEBI_39142 a rdfs:Class ;
rdfs:label "Bronsted base" ;
rdfs:comment "A molecular entity capable of accepting a hydron from a donor (Brønsted acid)." ;
rdfs:subClassOf obo:CHEBI_15339 , obo:CHEBI_22695 .
obo:CHEBI_38106 a rdfs:Class ;
rdfs:label "organosulfur heterocyclic compound" ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33261 .
obo:WBPhenotype_0002197 a rdfs:Class ;
rdfs:label "voltage gated channel activity variant" ;
rdfs:comment "Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded is altered from that observed for controls." ;
rdfs:subClassOf obo:WBPhenotype_0001315 .
obo:WBPhenotype_0001494 a rdfs:Class ;
rdfs:label "distal tip cell migration precocious" ;
rdfs:comment "DTCs migrate at an earlier stage of development, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000195 , obo:WBPhenotype_0000439 .
obo:WBPhenotype_0001997 a rdfs:Class ;
rdfs:label "nuclear anchoring variant" ;
rdfs:comment "The nucleus or nuclei are not positioned in a similar manner or pattern in the cell or syncytium to that observed in controls." ;
rdfs:subClassOf obo:WBPhenotype_0000511 .
obo:WBPhenotype_0000488 a rdfs:Class ;
rdfs:label "chloroquine hypersensitive" ;
rdfs:comment "Animals respond to chloroquine at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000802 a rdfs:Class ;
rdfs:label "dorsal region development variant" ;
rdfs:comment "Variations in the progression of an animal's anatomy contained in the dorsal region over time, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000578 .
obo:GO_0007033 a rdfs:Class ;
rdfs:label "vacuole organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." ;
rdfs:subClassOf obo:GO_0006996 .
obo:PATO_0000057 a rdfs:Class ;
rdfs:label "occurrence" ;
rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence." ;
rdfs:subClassOf obo:PATO_0002323 .
obo:WBPhenotype_0000448 a rdfs:Class ;
rdfs:label "adult cuticle development variant" ;
rdfs:comment "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time in adults compared to control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000447 .
obo:GO_0051223 a rdfs:Class ;
rdfs:label "regulation of protein transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 , obo:GO_0070201 .
obo:WBPhenotype_0000501 a rdfs:Class ;
rdfs:label "left handed roller" ;
rdfs:comment "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the left-handed direction. In liquid media, wave propogation is helical rather than planar." ;
rdfs:subClassOf obo:WBPhenotype_0000645 .
obo:WBPhenotype_0001033 a rdfs:Class ;
rdfs:label "proximal germ cell proliferation variant" ;
rdfs:comment "Any variation in the spatial pattern of proliferation and differentiation in the germ line compared to control. In C. elegans, this refers to an ectopic mass of proliferating germ cells that occupies the proximal adult germ line, a region normally occupied by gametes." ;
rdfs:subClassOf obo:WBPhenotype_0001215 .
obo:GO_2001222 a rdfs:Class ;
rdfs:label "regulation of neuron migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuron migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:GO_0007129 a rdfs:Class ;
rdfs:label "homologous chromosome pairing at meiosis" ;
rdfs:comment "The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete." ;
rdfs:subClassOf obo:GO_0070192 .
obo:GO_1901881 a rdfs:Class ;
rdfs:label "positive regulation of protein depolymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein depolymerization." ;
rdfs:subClassOf obo:GO_0043243 , obo:GO_0065007 , obo:GO_1901879 .
obo:GO_0038024 a rdfs:Class ;
rdfs:label "cargo receptor activity" ;
rdfs:comment "Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span membranes (for instance the plasma membrane or the endoplasmic reticulum membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit the cargo molecules to nascent vesicles." ;
rdfs:subClassOf obo:GO_0003674 .
obo:WBPhenotype_0000079 a rdfs:Class ;
rdfs:label "branched adult alae" ;
rdfs:comment "The small linear ridges running along the lateral lines of the cuticle of adults are branched as opposed to having an unbiforcated arrangement, lengthwise along the body (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001412 .
obo:WBPhenotype_0000993 a rdfs:Class ;
rdfs:label "anal depressor contraction defect" ;
rdfs:comment "Animals fail to contract the anal depressor muscle." ;
rdfs:subClassOf obo:WBPhenotype_0001092 .
obo:GO_2000380 a rdfs:Class ;
rdfs:label "regulation of mesoderm development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mesoderm development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:WBPhenotype_0000673 a rdfs:Class ;
rdfs:label "brood size variant" ;
rdfs:comment "The number of offspring produced is altered compared to that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000806 .
obo:WBPhenotype_0001573 a rdfs:Class ;
rdfs:label "nicotine response variant" ;
rdfs:comment "Animals exhibit variations in the response to the addition of nicotine compared to that observed in control animals. Nicotine is a cholinergic agonist." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0001073 a rdfs:Class ;
rdfs:label "egg laying response to food variant" ;
rdfs:comment "Animals exhibit variations in egg-laying behavior in response to food compared to control. In C. elegans, well-fed animals lay more eggs compared with starved animals." ;
rdfs:subClassOf obo:WBPhenotype_0000640 , obo:WBPhenotype_0001072 .
obo:WBPhenotype_0002028 a rdfs:Class ;
rdfs:label "mechanoreceptor current variant" ;
rdfs:comment "Animals differ from controls in their electrical response to mechanical stimulus." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:WBPhenotype_0000415 a rdfs:Class ;
rdfs:label "necrotic cell death variant" ;
rdfs:comment "Animals exhibit variations in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000729 .
obo:WBPhenotype_0001117 a rdfs:Class ;
rdfs:label "cell cell contacts abnormal early emb" ;
rdfs:comment "Cell-cell contacts are abnormal in the early embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0002404 .
obo:CHEBI_20702 a rdfs:Class ;
rdfs:label "2-aminopurines" ;
rdfs:comment "Any aminopurine having the amino substituent at the 2-position." ;
rdfs:subClassOf obo:CHEBI_22527 .
obo:CHEBI_33257 a rdfs:Class ;
rdfs:label "secondary amide" ;
rdfs:comment "A derivative of two oxoacids RkE(=O)l(OH)m (l ≠ 0) in which two acyl groups are attached to the amino or substituted amino group." ;
rdfs:subClassOf obo:CHEBI_32988 .
obo:WBPhenotype_0000667 a rdfs:Class ;
rdfs:label "gonad displaced" ;
rdfs:comment "The specialized tissue of the reproductive tract that produces gamete is shifted from its customary place as defined by control." ;
rdfs:subClassOf obo:WBPhenotype_0000977 .
obo:WBPhenotype_0001874 a rdfs:Class ;
rdfs:label "protein neddylation variant" ;
rdfs:comment "Any variation in the conjugation of the ubiquitin-like protein Nedd8 to another protein compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001382 .
obo:GO_0060179 a rdfs:Class ;
rdfs:label "male mating behavior" ;
rdfs:comment "The specific behavior of a male organism that is associated with reproduction." ;
rdfs:subClassOf obo:GO_0007617 .
obo:WBPhenotype_0000896 a rdfs:Class ;
rdfs:label "obsolete oocyte germ cell differentiation abnormal" ;
rdfs:comment "OBSOLETE." .
obo:CHEBI_23982 a rdfs:Class ;
rdfs:label "ethanols" ;
rdfs:comment "Any primary alcohol based on an ethanol skeleton." ;
rdfs:subClassOf obo:CHEBI_15734 .
obo:GO_0036490 a rdfs:Class ;
rdfs:label "regulation of translation in response to endoplasmic reticulum stress" ;
rdfs:comment "Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." ;
rdfs:subClassOf obo:GO_0043555 , obo:GO_0065007 .
obo:CHEBI_25741 a rdfs:Class ;
rdfs:label "oxide" ;
rdfs:comment "An oxide is a chemical compound of oxygen with other chemical elements." ;
rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_37577 .
obo:WBPhenotype_0002015 a rdfs:Class ;
rdfs:label "voltage measurement variant" ;
rdfs:comment "Any observed variation in the measurement of voltage across the cell membrane compared to measurements in control animals. Voltage is the difference in electric potential energy per unit charge between two points." ;
rdfs:subClassOf obo:WBPhenotype_0001315 .
obo:WBPhenotype_0000151 a rdfs:Class ;
rdfs:label "anterior pharynx extra cells" ;
rdfs:comment "Embryos generate an excess number of anterior derived pharyngeal cells. In C. elegans, embryos generate an excess number of AB blastomere-derived pharyngeal cells. This hyperinduction of anterior pharyngeal tissue is associated with defects in fate specification of the ABp blastomere." ;
rdfs:subClassOf obo:WBPhenotype_0000115 , obo:WBPhenotype_0002175 .
obo:GO_0006997 a rdfs:Class ;
rdfs:label "nucleus organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." ;
rdfs:subClassOf obo:GO_0006996 .
obo:GO_0044092 a rdfs:Class ;
rdfs:label "negative regulation of molecular function" ;
rdfs:comment "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:WBPhenotype_0002248 a rdfs:Class ;
rdfs:label "hypersensitive to zinc deficiency" ;
rdfs:comment "Animals exhibit detrimental responses to zinc deficiency more readily than control animals" ;
rdfs:subClassOf obo:WBPhenotype_0001849 .
obo:CHEBI_35604 a rdfs:Class ;
rdfs:label "carbon oxoanion" ;
rdfs:comment "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOyn− for some integers x, y and n." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_35406 , obo:CHEBI_36963 .
obo:GO_1902338 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic process involved in morphogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904746 .
obo:WBPhenotype_0002530 a rdfs:Class ;
rdfs:label "axotomy-induced phosphatidylserine exposure abnormal"@en ;
rdfs:comment "The level of phosphatidylserine exposed on the external axonal membrane following transection (axotomy) is changed compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001399 , obo:WBPhenotype_0002478 .
obo:CHEBI_51374 a rdfs:Class ;
rdfs:label "GABA agent" ;
rdfs:comment "A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems." ;
rdfs:subClassOf obo:CHEBI_35942 .
obo:PATO_0001599 a rdfs:Class ;
rdfs:label "rotated" ;
rdfs:comment "An oriented quality inhering in a bearer by virtue of the bearer's being relocated around an axis." ;
rdfs:subClassOf obo:PATO_0000614 .
obo:WBPhenotype_0002430 a rdfs:Class ;
rdfs:label "mitochondrial DNA damage variant" ;
rdfs:comment "Any variation in the extent of mitochondrial DNA damage observed compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000732 .
obo:GO_0051252 a rdfs:Class ;
rdfs:label "regulation of RNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." ;
rdfs:subClassOf obo:GO_0019219 , obo:GO_0060255 , obo:GO_0065007 .
obo:WBPhenotype_0000464 a rdfs:Class ;
rdfs:label "oxygen response variant" ;
rdfs:comment "Animals exhibit variations in their response to oxygen compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:CHEBI_48001 a rdfs:Class ;
rdfs:label "protein synthesis inhibitor" ;
rdfs:comment "A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein." ;
rdfs:subClassOf obo:CHEBI_76932 .
obo:WBPhenotype_0000352 a rdfs:Class ;
rdfs:label "backing uncoordinated" ;
rdfs:comment "Backward movement is not coordinated as in control. This often causes jerky or spastic backward locomotion." ;
rdfs:subClassOf obo:WBPhenotype_0001005 .
obo:GO_0048522 a rdfs:Class ;
rdfs:label "positive regulation of cellular process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0050925 a rdfs:Class ;
rdfs:label "negative regulation of negative chemotaxis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." ;
rdfs:subClassOf obo:GO_0050922 , obo:GO_0050923 , obo:GO_0065007 .
obo:PATO_0000068 a rdfs:Class ;
rdfs:label "qualitative" ;
rdfs:comment "A quality of an entity that is descriptive or observational, typically not represented numerically." ;
rdfs:subClassOf obo:PATO_0000001 .
obo:GO_0032876 a rdfs:Class ;
rdfs:label "negative regulation of DNA endoreduplication" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0032875 , obo:GO_0065007 , obo:GO_2000104 .
obo:WBPhenotype_0001809 a rdfs:Class ;
rdfs:label "organelle fusion defective" ;
rdfs:comment "The formation of mature intracellular compartments via membrane fusion is disrupted." ;
rdfs:subClassOf obo:WBPhenotype_0001344 .
obo:WBPhenotype_0001952 a rdfs:Class ;
rdfs:label "germline nuclear positioning variant" ;
rdfs:comment "Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000511 .
obo:WBPhenotype_0001088 a rdfs:Class ;
rdfs:label "pentanol chemotaxis defective" ;
rdfs:comment "Failure to execute characteristic response to pentanol compared to control. In C. elegans, animals move towards typically attractive concentrations of pentanol." ;
rdfs:subClassOf obo:WBPhenotype_0001438 , obo:WBPhenotype_0001473 .
obo:WBPhenotype_0001405 a rdfs:Class ;
rdfs:label "protein aggregation variant" ;
rdfs:comment "Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding." ;
rdfs:subClassOf obo:WBPhenotype_0001370 .
obo:GO_0007626 a rdfs:Class ;
rdfs:label "locomotory behavior" ;
rdfs:comment "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." ;
rdfs:subClassOf obo:GO_0007610 .
obo:WBPhenotype_0000190 a rdfs:Class ;
rdfs:label "no dauer recovery" ;
rdfs:comment "Animals fail to exit from the facultative diapause of the dauer larval stage of nematode development." ;
rdfs:subClassOf obo:WBPhenotype_0000127 .
obo:GO_0009308 a rdfs:Class ;
rdfs:label "amine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ;
rdfs:subClassOf obo:GO_0008152 .
obo:WBPhenotype_0001005 a rdfs:Class ;
rdfs:label "backward locomotion variant" ;
rdfs:comment "Variations in the spontaneous or induced backward crawling locomotion of an animal compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002320 .
obo:WBls_0000017 a rdfs:Class ;
rdfs:label "comma embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 390-420min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo looks like a comma. A stage between bean embryo and 1.5-fold embryo." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000810 .
obo:WBPhenotype_0000015 a rdfs:Class ;
rdfs:label "positive chemotaxis defective" ;
rdfs:comment "Variations in the movement towards typically attractive chemicals." ;
rdfs:subClassOf obo:WBPhenotype_0000635 .
obo:GO_0007140 a rdfs:Class ;
rdfs:label "male meiotic nuclear division" ;
rdfs:comment "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline." ;
rdfs:subClassOf obo:GO_0000280 , obo:GO_0140013 .
obo:WBPhenotype_0001524 a rdfs:Class ;
rdfs:label "quiescence variant" ;
rdfs:comment "Exhibition of quiescent behavior under inappropriate conditions and improper recovery from quiescent state. Quiescent behavior is normally coupled with lethargus." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:WBPhenotype_0000938 a rdfs:Class ;
rdfs:label "male V lineages variant" ;
rdfs:comment "The descendants of any of the V precursor cells (V1-V6) in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000809 .
obo:GO_1900409 a rdfs:Class ;
rdfs:label "positive regulation of cellular response to oxidative stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0065007 , obo:GO_1900407 , obo:GO_1902884 .
obo:CHEBI_18154 a rdfs:Class ;
rdfs:label "polysaccharide" ;
rdfs:comment "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." ;
rdfs:subClassOf obo:CHEBI_16646 , obo:CHEBI_167559 , obo:CHEBI_33694 .
obo:WBPhenotype_0001845 a rdfs:Class ;
rdfs:label "lipid modification variant" ;
rdfs:comment "Variations in the covalent alteration of one or more components (eg: fatty acids, sterols etc.) in a lipid, resulting in a change in the properties of the lipid, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000725 .
obo:WBPhenotype_0001167 a rdfs:Class ;
rdfs:label "pseudocleavage defective early emb" ;
rdfs:comment "Pseudocleavage is atypical in the inviable one-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001100 .
obo:GO_0005759 a rdfs:Class ;
rdfs:label "mitochondrial matrix" ;
rdfs:comment "The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation." ;
rdfs:subClassOf obo:GO_0070013 .
obo:GO_0060143 a rdfs:Class ;
rdfs:label "positive regulation of syncytium formation by plasma membrane fusion" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0060142 , obo:GO_0065007 .
obo:GO_0016020 a rdfs:Class ;
rdfs:label "membrane" ;
rdfs:comment "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0002105 a rdfs:Class ;
rdfs:label "late endosome localization variant" ;
rdfs:comment "Any variation in the subcellular localization of membrane bound organelles, known as late endosomes, that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002100 .
obo:WBPhenotype_0002080 a rdfs:Class ;
rdfs:label "peptide uptake by intestinal cell variant" ;
rdfs:comment "Animals exhibit variations in the degree to which or manner in which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001763 .
obo:WBPhenotype_0001140 a rdfs:Class ;
rdfs:label "neuron migration variant" ;
rdfs:comment "Any variation in the normal orderly movement of neurons from one site to another compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000594 , obo:WBPhenotype_0000816 .
obo:WBPhenotype_0000951 a rdfs:Class ;
rdfs:label "socket cell development variant" ;
rdfs:comment "Any variation in the progression of a socket cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000942 .
obo:WBPhenotype_0000224 a rdfs:Class ;
rdfs:label "serotonin deficient" ;
rdfs:comment "Animals do not contain or are unable to maintain a perceivable level of serotonin capable of initiating or maintaining serotonin-dependent cell activity." ;
rdfs:subClassOf obo:WBPhenotype_0000222 .
obo:GO_0007492 a rdfs:Class ;
rdfs:label "endoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." ;
rdfs:subClassOf obo:GO_0009888 .
obo:WBPhenotype_0000109 a rdfs:Class ;
rdfs:label "obsolete moderate dumpy" ;
rdfs:comment "OBSOLETE." .
obo:CL_0000211 a rdfs:Class ;
rdfs:label "electrically active cell" ;
rdfs:comment "A cell whose function is determined by the generation or the reception of an electric signal." ;
rdfs:subClassOf obo:CL_0000000 .
obo:CHEBI_47266 a rdfs:Class ;
rdfs:label "hydrogen bromide" ;
rdfs:comment "A diatomic molecule containing covalently bonded hydrogen and bromine atoms." ;
rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18140 , obo:CHEBI_37176 .
obo:CHEBI_30566 a rdfs:Class ;
rdfs:label "gamma-aminobutyrate" ;
rdfs:comment "An γ-amino acid anion resulting from the deprotonation of the carboxy group of γ-aminobutyric acid." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_71666 .
obo:WBPhenotype_0002157 a rdfs:Class ;
rdfs:label "translation repression variant" ;
rdfs:comment "The extent of translational repression varies from controls." ;
rdfs:subClassOf obo:WBPhenotype_0000121 .
obo:WBPhenotype_0000347 a rdfs:Class ;
rdfs:label "rectal development variant" ;
rdfs:comment "Any variation in the progression of the cuticle-lined sinus opening on the posterior ventral surface of the animal over time from its formation to its mature structure compared to control (Wormatlas). The function of the rectum is to excrete waste products from the alimentary system." ;
rdfs:subClassOf obo:WBPhenotype_0000617 .
obo:CHEBI_37416 a rdfs:Class ;
rdfs:label "EC 2.7.7.6 (RNA polymerase) inhibitor" ;
rdfs:comment "An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6)." ;
rdfs:subClassOf obo:CHEBI_76815 .
obo:GO_0048515 a rdfs:Class ;
rdfs:label "spermatid differentiation" ;
rdfs:comment "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0022412 , obo:GO_0030154 .
obo:GO_0048583 a rdfs:Class ;
rdfs:label "regulation of response to stimulus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:GO_0034330 a rdfs:Class ;
rdfs:label "cell junction organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." ;
rdfs:subClassOf obo:GO_0016043 .
obo:GO_2000018 a rdfs:Class ;
rdfs:label "regulation of male gonad development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of male gonad development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905939 .
obo:WBPhenotype_0001963 a rdfs:Class ;
rdfs:label "homolog association variant" ;
rdfs:comment "The association of homologs during diakinesis and the maintenance of their association through meiosis I as well as the preservation of centromeric cohesin between sister chromatids does not proceed as it does in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001824 .
obo:CHEBI_33247 a rdfs:Class ;
rdfs:label "organic group" ;
rdfs:comment "Any substituent group or skeleton containing carbon." ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:GO_1901530 a rdfs:Class ;
rdfs:label "response to hypochlorite" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus." ;
rdfs:subClassOf obo:GO_0000302 .
obo:GO_0140534 a rdfs:Class ;
rdfs:label "endoplasmic reticulum protein-containing complex" ;
rdfs:comment "A protein complex that is part of an endoplasmic reticulum." ;
rdfs:subClassOf obo:GO_0032991 .
obo:GO_0140975 a rdfs:Class ;
rdfs:label "disruption of cellular anatomical structure in another organism" ;
rdfs:comment "The disruption of a cellular component of another organism, leading to damage or temporary subversion of that structure. In some cases this can cause malfunctioning of the cells and death of the target organism." ;
rdfs:subClassOf obo:GO_0141060 .
obo:WBPhenotype_0001986 a rdfs:Class ;
rdfs:label "high temperature induced L1 arrest" ;
rdfs:comment "Animals undergo an irreversible high temperature-induced developmental arrest during the first larval stage." ;
rdfs:subClassOf obo:WBPhenotype_0000081 , obo:WBPhenotype_0001273 .
obo:CHEBI_39219 a rdfs:Class ;
rdfs:label "avermectin acaricide" ;
rdfs:subClassOf obo:CHEBI_39218 , obo:CHEBI_39220 .
obo:GO_1903188 a rdfs:Class ;
rdfs:label "positive regulation of vitellogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vitellogenesis." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1903186 .
obo:CHEBI_176497 a rdfs:Class ;
rdfs:label "geroprotector" ;
rdfs:comment "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan." ;
rdfs:subClassOf obo:CHEBI_50267 .
obo:WBPhenotype_0002595 a rdfs:Class ;
rdfs:label "sleep deprivation-induced brood size reduction enhanced"@en ;
rdfs:comment "The reduction in brood size caused by sleep deprivation is enhanced, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000154 .
obo:CHEBI_26607 a rdfs:Class ;
rdfs:label "saturated fatty acid" ;
rdfs:comment "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:WBPhenotype_0000486 a rdfs:Class ;
rdfs:label "colchicine hypersensitive" ;
rdfs:comment "Animals respond to colchicine at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000097 a rdfs:Class ;
rdfs:label "AB lineage variant" ;
rdfs:comment "The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000824 .
obo:GO_0071174 a rdfs:Class ;
rdfs:label "mitotic spindle checkpoint signaling" ;
rdfs:comment "A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form." ;
rdfs:subClassOf obo:GO_0007093 , obo:GO_0031577 .
obo:CHEBI_18367 a rdfs:Class ;
rdfs:label "phosphate(3-)" ;
rdfs:comment "A phosphate ion that is the conjugate base of hydrogenphosphate." ;
rdfs:subClassOf obo:CHEBI_35780 , obo:CHEBI_79387 .
obo:WBPhenotype_0001670 a rdfs:Class ;
rdfs:label "presynaptic vesicle number reduced" ;
rdfs:comment "Animals exhibit an overall decrease in the quantity of synaptic vesicles at the synapse compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001669 .
obo:GO_0051656 a rdfs:Class ;
rdfs:label "establishment of organelle localization" ;
rdfs:comment "The directed movement of an organelle to a specific location." ;
rdfs:subClassOf obo:GO_0051234 , obo:GO_0051640 .
obo:WBPhenotype_0000695 a rdfs:Class ;
rdfs:label "vulva morphology variant" ;
rdfs:comment "Animals exhibit variations in the gross structure or organization of the reproductive organ required for depositing eggs and for influencing male mating behavior compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001335 , obo:WBPhenotype_0002553 .
obo:WBPhenotype_0001178 a rdfs:Class ;
rdfs:label "egg integrity defective early emb" ;
rdfs:comment "The structure of the egg is impaired, flawed or no longer intact." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0002075 .
obo:CHEBI_16856 a rdfs:Class ;
rdfs:label "glutathione" ;
rdfs:comment "A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine." ;
rdfs:subClassOf obo:CHEBI_29256 , obo:CHEBI_47923 , obo:CHEBI_83824 .
obo:CHEBI_38632 a rdfs:Class ;
rdfs:label "membrane transport modulator" ;
rdfs:comment "Any agent that affects the transport of molecular entities across a biological membrane." ;
rdfs:subClassOf obo:CHEBI_52208 .
obo:WBPhenotype_0001823 a rdfs:Class ;
rdfs:label "sperm recruitment variant" ;
rdfs:comment "Any variation in the mechanism by which sperm find their correct target destinations (spermatheca)." ;
rdfs:subClassOf obo:WBPhenotype_0001424 .
obo:WBPhenotype_0002172 a rdfs:Class ;
rdfs:label "pathogen release variant" ;
rdfs:comment "Infected animals exhibit variations in the process of releasing pathogens back into the environment, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001012 .
obo:CHEBI_39832 a rdfs:Class ;
rdfs:label "methoxyethane" ;
rdfs:comment "An ether that is the methyl ether derivative of ethanol." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25698 .
obo:GO_1905910 a rdfs:Class ;
rdfs:label "negative regulation of dauer entry" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry." ;
rdfs:subClassOf obo:GO_0061067 , obo:GO_0065007 , obo:GO_1905909 .
obo:WBPhenotype_0001051 a rdfs:Class ;
rdfs:label "cation positive chemotaxis variant" ;
rdfs:comment "Animals exhibit variations in the characteristic movement towards typically attractive cations compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001047 .
obo:GO_0016246 a rdfs:Class .
obo:WBbt_0005298 a rdfs:Class ;
rdfs:label "ventral ganglion" ;
rdfs:comment "ganglion lies beside the nerve ring in the head, just anterior of the retrovesicular ganglion. It contains about 20 interneuron and motorneuron cell bodies that all send their neuronal processes into the ring. The cell bodies are divided into two groups by the intrusion of the excretory duct and canal. The cells are bounded by a basal lamina which physically separates them from the lateral ganglion even though they are adjacent to one another." ;
rdfs:subClassOf obo:WBbt_0005135 .
obo:WBPhenotype_0001863 a rdfs:Class ;
rdfs:label "manganese response variant" ;
rdfs:comment "Animals exhibit variations in their response to manganese compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 , obo:WBPhenotype_0000591 .
obo:WBPhenotype_0001011 a rdfs:Class ;
rdfs:label "complex phenotype early emb" ;
rdfs:comment "Population of unhatched eggs exhibit a complex combination of defects that do not match other class definitions." ;
rdfs:subClassOf obo:WBPhenotype_0001007 .
obo:WBPhenotype_0000927 a rdfs:Class ;
rdfs:label "male longitudinal muscle morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the male longitudinal muscle compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000923 , obo:WBPhenotype_0000924 .
obo:CHEBI_46629 a rdfs:Class ;
rdfs:label "oxo group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:GO_0000422 a rdfs:Class ;
rdfs:label "autophagy of mitochondrion" ;
rdfs:comment "The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions." ;
rdfs:subClassOf obo:GO_0006914 .
obo:WBPhenotype_0001715 a rdfs:Class ;
rdfs:label "pirouette frequency variant" ;
rdfs:comment "Animals exhibit variations in the number of directional changes over time from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001714 .
obo:CHEBI_58954 a rdfs:Class ;
rdfs:label "straight-chain saturated fatty acid anion" ;
rdfs:comment "Any saturated fatty acid anion lacking a carbon side-chain." ;
rdfs:subClassOf obo:CHEBI_58953 .
obo:WBPhenotype_0001632 a rdfs:Class ;
rdfs:label "diplo X gamete" ;
rdfs:comment "Animals produce ova/sperm that contain 2 X chromosomes." ;
rdfs:subClassOf obo:WBPhenotype_0001664 .
obo:PATO_0001598 a rdfs:Class ;
rdfs:label "protruding" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's extending out above or beyond a surface or boundary." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:CHEBI_78116 a rdfs:Class ;
rdfs:label "fatty acid anion 6:0" ;
rdfs:comment "Any saturated fatty acid anion containing 6 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_58953 , obo:CHEBI_59558 .
obo:CHEBI_25105 a rdfs:Class ;
rdfs:label "macrolide antibiotic" ;
rdfs:comment "A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25106 .
obo:GO_0072662 a rdfs:Class ;
rdfs:label "protein localization to peroxisome" ;
rdfs:comment "A process in which a protein is transported to, or maintained at, a location in a peroxisome." ;
rdfs:subClassOf obo:GO_0007031 , obo:GO_0033365 .
obo:WBPhenotype_0000829 a rdfs:Class ;
rdfs:label "Q lineage variant" ;
rdfs:comment "The descendants of Q L or QR cells exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000825 .
obo:GO_0008361 a rdfs:Class ;
rdfs:label "regulation of cell size" ;
rdfs:comment "Any process that modulates the size of a cell." ;
rdfs:subClassOf obo:GO_0032535 .
obo:WBbt_0005811 a rdfs:Class ;
rdfs:label "neuronal sheath cell" ;
rdfs:comment "a structural (glial) cell which forms an specialized environment surrounding the sensory ending(s) of one or more neurons; sometimes accompanied by a more distal socket cell. In early development of the sensory nerves and of the nerve ring some sheath cells (cephalics and labials) may also provide a substrate for axon guidance" ;
rdfs:subClassOf obo:WBbt_0005754 , obo:WBbt_0005762 .
obo:GO_1902751 a rdfs:Class ;
rdfs:label "positive regulation of cell cycle G2/M phase transition" ;
rdfs:comment "Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901989 , obo:GO_1902749 .
obo:GO_0051320 a rdfs:Class ;
rdfs:label "S phase" ;
rdfs:comment "The cell cycle phase, following G1, during which DNA synthesis takes place." ;
rdfs:subClassOf obo:GO_0022403 .
obo:WBPhenotype_0000815 a rdfs:Class ;
rdfs:label "muscle cell development variant" ;
rdfs:comment "Any variation in the progression of a muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000529 , obo:WBPhenotype_0000622 .
obo:WBPhenotype_0000940 a rdfs:Class ;
rdfs:label "male P lineages variant" ;
rdfs:comment "The descendants of any of the P precursor cells (P1-P12) in male animals exhibit any variation in developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000809 .
obo:WBPhenotype_0001664 a rdfs:Class ;
rdfs:label "X chromosome nondisjunction" ;
rdfs:comment "The frequency of sex chromosome segregation is perturbed, resulting in the production of exceptional gametes (e.g. ova or sperm) and populations with a sex ratio altered from the rate of 1:500 as observed for control populations." ;
rdfs:subClassOf obo:WBPhenotype_0001174 .
obo:WBPhenotype_0002659 a rdfs:Class ;
rdfs:label "muscle strength decreased"@en ;
rdfs:comment "Animals exhibit a decrease in muscle strength, as measured by a strength determining assay, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002658 .
obo:WBPhenotype_0000602 a rdfs:Class ;
rdfs:label "obsolete excretory system morphology abnormal" ;
rdfs:comment "OBSOLETE." .
obo:CHEBI_76932 a rdfs:Class ;
rdfs:label "pathway inhibitor" ;
rdfs:comment "An enzyme inhibitor that interferes with one or more steps in a metabolic pathway." ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:WBPhenotype_0002150 a rdfs:Class ;
rdfs:label "exo-RNAi response variant" ;
rdfs:comment "RNAi silencing mechanisms triggered by exogenously introduced (foreign) dsRNA, do not work to the same degree as in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:WBbt_0008249 a rdfs:Class ;
rdfs:label "gon_male_sves Z1 or Z4" ;
rdfs:comment "seminal vesicle, outer; cell of the pedigree Z1.paapp or Z4.aaapp." ;
rdfs:subClassOf obo:WBbt_0008189 .
obo:GO_0031570 a rdfs:Class ;
rdfs:label "DNA integrity checkpoint signaling" ;
rdfs:comment "A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes." ;
rdfs:subClassOf obo:GO_0000075 .
obo:WBPhenotype_0000835 a rdfs:Class ;
rdfs:label "F lineage variant" ;
rdfs:comment "The descendants of the F cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000809 .
obo:WBPhenotype_0001946 a rdfs:Class ;
rdfs:label "pachytene progression during oogenesis variant" ;
rdfs:comment "Developing oocytes show defects in their entry, progression through or exit from the pachytene stage compared to control animals. Pachytene is a cell cycle process comprising the steps by which a cell progresses through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome." ;
rdfs:subClassOf obo:WBPhenotype_0001824 .
obo:GO_0000960 a rdfs:Class ;
rdfs:label "regulation of mitochondrial RNA catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0051252 , obo:GO_0065007 .
obo:WBls_0000004 a rdfs:Class ;
rdfs:label "proliferating embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 0-350min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 560 cells. From start of first cleavage until cleavage is over." ;
rdfs:subClassOf obo:WBls_0000812 .
obo:CHEBI_33287 a rdfs:Class ;
rdfs:label "fertilizer" ;
rdfs:comment "A fertilizer is any substance that is added to soil or water to assist the growth of plants." ;
rdfs:subClassOf obo:CHEBI_33286 .
obo:CHEBI_32451 a rdfs:Class ;
rdfs:label "D-cysteinium" ;
rdfs:comment "The D-enantiomer of cysteinium." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_32458 .
obo:CHEBI_33535 a rdfs:Class ;
rdfs:label "sulfur hydride" ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_36902 .
obo:CHEBI_194338 a rdfs:Class ;
rdfs:label "T-type calcium channel blocker" ;
rdfs:comment "Any agent that interferes with the activity of T-type calcium channels." ;
rdfs:subClassOf obo:CHEBI_38215 .
obo:WBPhenotype_0000454 a rdfs:Class ;
rdfs:label "head twisted" ;
rdfs:comment "The anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring)of the body appears distorted, usually due to uncharacteristic winding." ;
rdfs:subClassOf obo:WBPhenotype_0000071 .
obo:WBPhenotype_0001755 a rdfs:Class ;
rdfs:label "UV induced mitotic germ cell arrest defective" ;
rdfs:comment "Animals do not arrest mitotic germ cell division, as control animals, when treated with UV radiation." ;
rdfs:subClassOf obo:WBPhenotype_0000100 .
obo:WBPhenotype_0001506 a rdfs:Class ;
rdfs:label "spontaneous reversal rate variant" ;
rdfs:comment "Any variation in the processes that govern the rate at which spontaneous backward locomotion is initiated compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001505 .
obo:WBPhenotype_0001022 a rdfs:Class ;
rdfs:label "hermaphrodite sexual development variant" ;
rdfs:comment "Genetically hermaphrodite animals exhibit deviations in the sexual program specific to hermaphrodites. In C. elegans, this refers to XX animals that develop as males or intersexuals instead of self-fertile hermaphrodites." ;
rdfs:subClassOf obo:WBPhenotype_0000822 .
obo:CHEBI_57867 a rdfs:Class ;
rdfs:label "nucleoside 5'-phosphate dianion" ;
rdfs:comment "The conjugate base of a nucleoside 5'-phosphate." ;
rdfs:subClassOf obo:CHEBI_58945 .
obo:GO_1990840 a rdfs:Class ;
rdfs:label "response to lectin" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties." ;
rdfs:subClassOf obo:GO_0009607 .
obo:WBls_0000817 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during larval stage"@en ;
rdfs:comment "A C. elegans life stage that occurs during the larval life stage" ;
rdfs:subClassOf obo:WBls_0000804 .
obo:GO_0018985 a rdfs:Class ;
rdfs:label "pronuclear envelope synthesis" ;
rdfs:comment "Synthesis and ordering of the envelope of pronuclei." ;
rdfs:subClassOf obo:GO_0006998 .
obo:GO_0007162 a rdfs:Class ;
rdfs:label "negative regulation of cell adhesion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." ;
rdfs:subClassOf obo:GO_0030155 , obo:GO_0048523 , obo:GO_0065007 .
obo:CHEBI_38077 a rdfs:Class ;
rdfs:label "polypyrrole" ;
rdfs:comment "A compound composed of two or more pyrrole units." ;
rdfs:subClassOf obo:CHEBI_38101 .
obo:WBPhenotype_0000523 a rdfs:Class ;
rdfs:label "chemical response variant" ;
rdfs:comment "Animals exhibit variations in their response to a specific chemical compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:GO_0099547 a rdfs:Class ;
rdfs:label "regulation of translation at synapse, modulating synaptic transmission" ;
rdfs:comment "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 , obo:GO_0140243 .
obo:GO_1901526 a rdfs:Class ;
rdfs:label "positive regulation of mitophagy" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitophagy." ;
rdfs:subClassOf obo:GO_0016239 , obo:GO_0065007 , obo:GO_1901524 , obo:GO_1903599 .
obo:WBPhenotype_0000374 a rdfs:Class ;
rdfs:label "early divisions prolonged" ;
rdfs:comment "The time interval in which early embryonic cell divisions occur is increased compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:CHEBI_35717 a rdfs:Class ;
rdfs:label "sedative" ;
rdfs:comment "A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety." ;
rdfs:subClassOf obo:CHEBI_35488 .
obo:GO_0043652 a rdfs:Class ;
rdfs:label "engulfment of apoptotic cell" ;
rdfs:comment "The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte." ;
rdfs:subClassOf obo:GO_0006911 .
obo:WBPhenotype_0000288 a rdfs:Class ;
rdfs:label "distal germline variant" ;
rdfs:comment "Variations in the progression of the lineages that gives rise to all germ cells, lying in the region adjacent to the proximal gonad (on the side furthest from the founder cells of the somatic gonad), over time compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000812 .
obo:PATO_0000001 a rdfs:Class ;
rdfs:label "quality" ;
rdfs:comment "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" ;
rdfs:subClassOf obo:BFO_0000020 .
obo:WBPhenotype_0001202 a rdfs:Class ;
rdfs:label "nicotine hypersensitive" ;
rdfs:comment "Animals respond to nicotine at lower concentrations or shorter exposure compared to control. Nicotine is a cholinergic agonist." ;
rdfs:subClassOf obo:WBPhenotype_0001573 , obo:WBPhenotype_0001579 , obo:WBPhenotype_0001918 .
obo:CHEBI_36962 a rdfs:Class ;
rdfs:label "organochalcogen compound" ;
rdfs:comment "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_33304 .
obo:WBPhenotype_0000255 a rdfs:Class ;
rdfs:label "amphid phasmid neuron morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid and phasmid sensilla from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." ;
rdfs:subClassOf obo:WBPhenotype_0001527 .
obo:WBPhenotype_0001106 a rdfs:Class ;
rdfs:label "spindle orientation variant AB or P1 early emb" ;
rdfs:comment "The orientation of the spindle is aberrant in either the AB or the P1 cell." ;
rdfs:subClassOf obo:WBPhenotype_0000760 .
obo:WBPhenotype_0001145 a rdfs:Class ;
rdfs:label "polar body number defective early emb" ;
rdfs:comment "Polar body number is abnormal in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001144 .
obo:GO_0032061 a rdfs:Class ;
rdfs:label "negative regulation of translation in response to osmotic stress" ;
rdfs:comment "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ;
rdfs:subClassOf obo:GO_0032055 , obo:GO_0043557 , obo:GO_0065007 .
obo:GO_0051240 a rdfs:Class ;
rdfs:label "positive regulation of multicellular organismal process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0051239 , obo:GO_0065007 .
obo:WBPhenotype_0000754 a rdfs:Class ;
rdfs:label "L4 larval development variant" ;
rdfs:comment "Variations in the progression of the fourth larval stage compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000750 .
obo:WBPhenotype_0002254 a rdfs:Class ;
rdfs:label "three prime target RNA uridylation reduced" ;
rdfs:comment "Three-prime (3') uridylation of mRNA targeted for silencing does not occur at the same rate or extent of targeted mRNA in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000028 .
obo:CHEBI_37887 a rdfs:Class ;
rdfs:label "adrenergic antagonist" ;
rdfs:comment "An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists." ;
rdfs:subClassOf obo:CHEBI_37962 .
obo:CHEBI_25990 a rdfs:Class ;
rdfs:label "phenylethanolamines" ;
rdfs:comment "An ethanolamine compound having a phenyl (substituted or unsubstituted) group on the carbon bearing the hydroxy substituent." ;
rdfs:subClassOf obo:CHEBI_23981 .
obo:WBPhenotype_0001185 a rdfs:Class ;
rdfs:label "embryonic developmental delay early emb" ;
rdfs:comment "The developmental progression of an early embryo over time, from its formation to its mature structure is delayed compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000848 , obo:WBPhenotype_0001100 .
obo:GO_0032057 a rdfs:Class ;
rdfs:label "negative regulation of translational initiation in response to stress" ;
rdfs:comment "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0045947 , obo:GO_0065007 .
obo:PATO_0000642 a rdfs:Class ;
rdfs:label "fused with" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer's being merged with another entity." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:GO_0022412 a rdfs:Class ;
rdfs:label "cellular process involved in reproduction in multicellular organism" ;
rdfs:comment "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0048609 .
obo:PATO_0000136 a rdfs:Class ;
rdfs:label "closure" ;
rdfs:comment "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:WBPhenotype_0001653 a rdfs:Class ;
rdfs:label "cadmium response variant" ;
rdfs:comment "Animals exhibit variations in their response to cadmium compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000591 .
obo:WBPhenotype_0001390 a rdfs:Class ;
rdfs:label "cell UV hypersensitive" ;
rdfs:comment "Cells respond to a lower dosage of UV or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000100 .
obo:WBPhenotype_0000653 a rdfs:Class ;
rdfs:label "mechanosensory system variant" ;
rdfs:comment "Variations in the progression of a set of interacting or interdependent entities forming the mechanosensory system over time from an initial condition to a later condition compared to control animals. The mechanosensory system is involved in the perception of a mechanical stimuli, its conversion into a signal and the recognition and characterization of the resulting signal." ;
rdfs:subClassOf obo:WBPhenotype_0000652 .
obo:CHEBI_33836 a rdfs:Class ;
rdfs:label "benzenoid aromatic compound" ;
rdfs:subClassOf obo:CHEBI_33598 , obo:CHEBI_33659 .
obo:WBPhenotype_0001766 a rdfs:Class ;
rdfs:label "cholesterol depletion hypersensitive" ;
rdfs:comment "Animals are more sensitive to the reduction of cholesterol in the environment compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000725 , obo:WBPhenotype_0002525 .
obo:WBPhenotype_0002318 a rdfs:Class ;
rdfs:label "dwelling reduced" ;
rdfs:comment "Animals exhibit a decrease in the low-speed/high turning movement that usually restricts them to a confined region compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000237 , obo:WBPhenotype_0002316 .
obo:WBPhenotype_0001247 a rdfs:Class ;
rdfs:label "anterograde transport defective" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons is disrupted." ;
rdfs:subClassOf obo:WBPhenotype_0000854 , obo:WBPhenotype_0001477 .
obo:WBPhenotype_0000341 a rdfs:Class ;
rdfs:label "imipramine hypersensitive" ;
rdfs:comment "Animals respond to imipramine at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000678 a rdfs:Class ;
rdfs:label "obsolete no copper sensitivity" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0002592 a rdfs:Class ;
rdfs:label "organism response to gravitational force abnormal"@en ;
rdfs:comment "Animals exhibit variations in their response to changes in gravitational force, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBPhenotype_0002074 a rdfs:Class ;
rdfs:label "centrosome dynamics variant" ;
rdfs:comment "Animals vary in the directed or coordinated movement of their centrosomes during cell division, compared to the pattern of movement observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:WBPhenotype_0000140 a rdfs:Class ;
rdfs:label "stress induced arrest variant" ;
rdfs:comment "Animals exhibit variations in cessation of development when exposed to stress stimuli that induce developmental arrest in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:GO_0032461 a rdfs:Class ;
rdfs:label "positive regulation of protein oligomerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein oligomerization." ;
rdfs:subClassOf obo:GO_0031334 , obo:GO_0032459 , obo:GO_0065007 .
obo:CHEBI_25555 a rdfs:Class ;
rdfs:label "nitrogen atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25585 , obo:CHEBI_33300 .
obo:GO_1905155 a rdfs:Class ;
rdfs:label "positive regulation of membrane invagination" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of membrane invagination." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1905153 .
obo:CHEBI_33672 a rdfs:Class ;
rdfs:label "heterobicyclic compound" ;
rdfs:comment "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." ;
rdfs:subClassOf obo:CHEBI_33636 , obo:CHEBI_5686 .
obo:WBPhenotype_0002237 a rdfs:Class ;
rdfs:label "endocytic recycling compartment organization and biogenesis defective" ;
rdfs:comment "Animals exhibit disruptions in tubular or tubulo-vesicular structures that function in endocytic transport from early to recycling endosomes." ;
rdfs:subClassOf obo:WBPhenotype_0001344 .
obo:WBPhenotype_0000475 a rdfs:Class ;
rdfs:label "muscle detached" ;
rdfs:comment "Animals fail to establish or maintain the connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues." ;
rdfs:subClassOf obo:WBPhenotype_0000474 .
obo:GO_0071692 a rdfs:Class ;
rdfs:label "protein localization to extracellular region" ;
rdfs:comment "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." ;
rdfs:subClassOf obo:GO_0033036 .
obo:WBPhenotype_0000469 a rdfs:Class ;
rdfs:label "Q neuroblast lineage migration variant" ;
rdfs:comment "The daughters of the Q neuroblasts exhibit variation in their characteristic movements compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001140 .
obo:PATO_0001851 a rdfs:Class ;
rdfs:label "swollen" ;
rdfs:comment "A structure quality inhering in a bearer by virtue of the bearer's exhibiting transient abnormal enlargement, not due to cell proliferation." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:WBPhenotype_0000690 a rdfs:Class ;
rdfs:label "gonad migration variant" ;
rdfs:comment "Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000624 .
obo:GO_0046907 a rdfs:Class ;
rdfs:label "intracellular transport" ;
rdfs:comment "The directed movement of substances within a cell." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0051641 , obo:GO_0051649 .
obo:CHEBI_64857 a rdfs:Class ;
rdfs:label "cosmetic" ;
rdfs:comment "The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:WBPhenotype_0008001 a rdfs:Class ;
rdfs:label "embryonic cell fate specification variant" ;
rdfs:comment "Any variation in the processes that govern acquisition of particular cell fates in the embryo, from the time of zygote formation until hatching compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000216 , obo:WBPhenotype_0000749 .
obo:CHEBI_22563 a rdfs:Class ;
rdfs:label "anion" ;
rdfs:comment "A monoatomic or polyatomic species having one or more elementary charges of the electron." ;
rdfs:subClassOf obo:CHEBI_24870 .
obo:PATO_0002037 a rdfs:Class ;
rdfs:label "degeneration" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer exhibiting deterioration of its structure." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:GO_0009890 a rdfs:Class ;
rdfs:label "negative regulation of biosynthetic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0009892 , obo:GO_0065007 .
obo:WBPhenotype_0001006 a rdfs:Class ;
rdfs:label "pharyngeal pumping rate variant" ;
rdfs:comment "The number of coordinated contraction-relaxation cycles (pumps) exhibited by the pharyngeal muscle deviates from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000634 .
obo:WBPhenotype_0001647 a rdfs:Class ;
rdfs:label "posterior pharynx variant" ;
rdfs:comment "Any variation in the progression of the posterior portion of the pharynx over time compared to control. In C. elegans the posterior region includes the isthmus and terminal bulb (second bulb)." ;
rdfs:subClassOf obo:WBPhenotype_0000707 .
obo:WBPhenotype_0001062 a rdfs:Class ;
rdfs:label "late paralysis arrested elongation two fold" ;
rdfs:comment "In C. elegans, movement and elongation stop nearly simultaneously soon after the twofold stage of elongation. However, mutant embryos twitch at the one-and-a-half-fold stage of elongation, like control animals, and move as well as control animals at the two- fold stage." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:GO_1905903 a rdfs:Class ;
rdfs:label "negative regulation of mesoderm formation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905902 , obo:GO_2000381 .
obo:WBPhenotype_0000538 a rdfs:Class ;
rdfs:label "obsolete synaptic output abnormal" ;
rdfs:comment "OBSOLETE." .
obo:GO_0061650 a rdfs:Class ;
rdfs:label "ubiquitin-like protein conjugating enzyme activity" ;
rdfs:comment "Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another molecule, usually another protein, via the reaction X-SCP + Y = Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue." ;
rdfs:subClassOf obo:GO_0019787 .
obo:GO_0031117 a rdfs:Class ;
rdfs:label "positive regulation of microtubule depolymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." ;
rdfs:subClassOf obo:GO_0031112 , obo:GO_0031114 , obo:GO_0065007 , obo:GO_1901881 , obo:GO_1902905 .
obo:GO_0002833 a rdfs:Class ;
rdfs:label "positive regulation of response to biotic stimulus" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." ;
rdfs:subClassOf obo:GO_0002831 , obo:GO_0048584 , obo:GO_0065007 .
obo:GO_2000242 a rdfs:Class ;
rdfs:label "negative regulation of reproductive process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0065007 , obo:GO_2000241 .
obo:WBPhenotype_0002348 a rdfs:Class ;
rdfs:label "frequency of body bends increased" ;
rdfs:comment "Animals exhibit an increase in the frequency of oscillations between adjacent body segments from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0004023 .
obo:CHEBI_46850 a rdfs:Class ;
rdfs:label "organoammonium salt" ;
rdfs:subClassOf obo:CHEBI_35276 .
obo:GO_0000958 a rdfs:Class ;
rdfs:label "mitochondrial mRNA catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ;
rdfs:subClassOf obo:GO_0000957 , obo:GO_0006402 .
obo:GO_0009416 a rdfs:Class ;
rdfs:label "response to light stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." ;
rdfs:subClassOf obo:GO_0009314 .
obo:GO_0032887 a rdfs:Class ;
rdfs:label "regulation of spindle elongation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0032886 , obo:GO_0065007 .
obo:WBPhenotype_0000389 a rdfs:Class ;
rdfs:label "hermaphrodite sperm fertilization defective" ;
rdfs:comment "Any perturbation that renders hermaphrodite derived sperm incompetent at fertilizing an oocyte." ;
rdfs:subClassOf obo:WBPhenotype_0000694 , obo:WBPhenotype_0002440 .
obo:WBPhenotype_0000824 a rdfs:Class ;
rdfs:label "embryonic cell lineage variant" ;
rdfs:comment "The descendants of an embryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000093 .
obo:WBPhenotype_0001275 a rdfs:Class ;
rdfs:label "increased genetic pathway signal" ;
rdfs:comment "Any variation that increases the magnitude of a signal generated by a set of gene interactions in a given pathway, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000074 .
obo:WBPhenotype_0001935 a rdfs:Class ;
rdfs:label "protein aggregation induced paralysis" ;
rdfs:comment "Animals become paralyzed in response to aggregation of proteins like poly-glutamine or beta-amyloid." ;
rdfs:subClassOf obo:WBPhenotype_0002425 .
obo:CHEBI_83970 a rdfs:Class ;
rdfs:label "cardiac glycoside" ;
rdfs:comment "Steroid lactones containing sugar residues that act on the contractile force of the cardiac muscles." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_24400 , obo:CHEBI_26766 .
obo:GO_0043052 a rdfs:Class ;
rdfs:label "thermotaxis" ;
rdfs:comment "The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature." ;
rdfs:subClassOf obo:GO_0009266 , obo:GO_0042330 .
obo:GO_1904357 a rdfs:Class ;
rdfs:label "negative regulation of telomere maintenance via telomere lengthening" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening." ;
rdfs:subClassOf obo:GO_0032205 , obo:GO_0065007 , obo:GO_1904356 .
obo:WBPhenotype_0000642 a rdfs:Class ;
rdfs:label "hyperactive" ;
rdfs:comment "Worms move forward or backward with an increased rate of body bends per minute compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000641 .
obo:WBPhenotype_0000720 a rdfs:Class ;
rdfs:label "obsolete pattern of reporter gene expression variant" ;
rdfs:comment "OBSOLETE." .
obo:GO_0050767 a rdfs:Class ;
rdfs:label "regulation of neurogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." ;
rdfs:subClassOf obo:GO_0051960 , obo:GO_0060284 , obo:GO_0065007 .
obo:GO_1903108 a rdfs:Class ;
rdfs:label "regulation of mitochondrial transcription" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of transcription occurring in the mitochondrion." ;
rdfs:subClassOf obo:GO_0006355 , obo:GO_0062125 , obo:GO_0065007 .
obo:WBPhenotype_0002546 a rdfs:Class ;
rdfs:label "bacterial load in gut variant"@en ;
rdfs:comment "Animals exhibit variations in the load of bacteria, of a particular clade or in general, in the gut, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002545 .
obo:WBPhenotype_0001159 a rdfs:Class ;
rdfs:label "pronuclear morphology defective early emb" ;
rdfs:comment "Pronucleus morphology is atypical in the inviable embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001151 .
obo:CHEBI_47802 a rdfs:Class ;
rdfs:label "5H-dibenzo[b,f]azepine" ;
rdfs:comment "A mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_36416 , obo:CHEBI_47804 .
obo:CHEBI_25944 a rdfs:Class ;
rdfs:label "pesticide" ;
rdfs:comment "Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:WBPhenotype_0002091 a rdfs:Class ;
rdfs:label "late endosome morphology variant" ;
rdfs:comment "Any variation in the form or composition of membrane bound organelles, known as late endosomes, that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002090 .
obo:CHEBI_39162 a rdfs:Class ;
rdfs:label "(R)-nicotine" ;
rdfs:comment "A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has R-configuration." ;
rdfs:subClassOf obo:CHEBI_138000 .
obo:GO_0019093 a rdfs:Class ;
rdfs:label "mitochondrial RNA localization" ;
rdfs:comment "Any process in which mitochondrial RNA is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0006403 .
obo:CHEBI_51280 a rdfs:Class ;
rdfs:label "S-methyl thioacetate" ;
rdfs:subClassOf obo:CHEBI_51277 .
obo:WBPhenotype_0001975 a rdfs:Class ;
rdfs:label "germ cell compartment large" ;
rdfs:comment "Germ cell compartments are larger than that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001973 .
obo:WBPhenotype_0001726 a rdfs:Class ;
rdfs:label "body length variant" ;
rdfs:comment "Animals vary in the distance between anterior and posterior ends of the animal from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000231 .
obo:GO_0031646 a rdfs:Class ;
rdfs:label "positive regulation of nervous system process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." ;
rdfs:subClassOf obo:GO_0031644 , obo:GO_0051240 , obo:GO_0065007 .
obo:WBPhenotype_0001707 a rdfs:Class ;
rdfs:label "nuclear import defective" ;
rdfs:comment "The directed movement of substances into the nucleus is impaired." ;
rdfs:subClassOf obo:WBPhenotype_0001705 .
obo:WBPhenotype_0001207 a rdfs:Class ;
rdfs:label "protein signaling variant" ;
rdfs:comment "Any variation in a series of protein mediated signals that help relay information within the cell, and thereby affecting changes in the functioning of the cell, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:WBPhenotype_0000638 a rdfs:Class ;
rdfs:label "molt defect" ;
rdfs:comment "Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage." ;
rdfs:subClassOf obo:WBPhenotype_0002041 .
obo:CHEBI_33661 a rdfs:Class ;
rdfs:label "monocyclic compound" ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:WBPhenotype_0002629 a rdfs:Class ;
rdfs:label "intestinal edema"@en ;
rdfs:comment "Animals exhibit edema (swelling) of the intestine, compared to control animals. This swelling is distinct from distension of the intestinal lumen (swollen intestinal lumen)." ;
rdfs:subClassOf obo:WBPhenotype_0000710 .
obo:WBPhenotype_0001304 a rdfs:Class ;
rdfs:label "hindgut damaged" ;
rdfs:comment "The terminal portion of the intestine exhibits structural defects such as scarring or blockage." ;
rdfs:subClassOf obo:WBPhenotype_0001298 .
obo:WBPhenotype_0000708 a rdfs:Class ;
rdfs:label "intestinal development variant" ;
rdfs:comment "Variations in the progression of the intestine over time from its initial formation to its mature structure compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000617 .
obo:GO_0031967 a rdfs:Class ;
rdfs:label "organelle envelope" ;
rdfs:comment "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0000138 a rdfs:Class ;
rdfs:label "lipid composition variant" ;
rdfs:comment "The constituent parts or ratio of elements that make up lipids are altered when compared to that of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000725 .
obo:WBPhenotype_0002359 a rdfs:Class ;
rdfs:label "protein carbonylation increased" ;
rdfs:comment "Animals exhibit an increase in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone." ;
rdfs:subClassOf obo:WBPhenotype_0002272 .
obo:WBPhenotype_0001378 a rdfs:Class ;
rdfs:label "mitotic chromosome segregation variant" ;
rdfs:comment "Any variation in the cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000773 , obo:WBPhenotype_0001743 .
obo:GO_0044090 a rdfs:Class ;
rdfs:label "positive regulation of vacuole organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0044088 , obo:GO_0065007 .
obo:WBPhenotype_0001787 a rdfs:Class ;
rdfs:label "phototaxis defective" ;
rdfs:comment "Animals do not respond via directed movement to light stimuli in the same manner as control animals. In C. elegans, animals move away from light." ;
rdfs:subClassOf obo:WBPhenotype_0001897 .
obo:GO_0099003 a rdfs:Class ;
rdfs:label "vesicle-mediated transport in synapse" ;
rdfs:comment "Any vesicle-mediated transport that occurs in a synapse." ;
rdfs:subClassOf obo:GO_0016192 .
obo:WBbt_0006796 a rdfs:Class ;
rdfs:label "germ cell" ;
rdfs:comment "a cell, of either sex, directly concerned in the production of a new organism." ;
rdfs:subClassOf obo:UBERON_0001062 , obo:WBbt_0004017 .
obo:GO_0006355 a rdfs:Class ;
rdfs:label "regulation of DNA-templated transcription" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0065007 , obo:GO_2001141 .
obo:WBPhenotype_0002112 a rdfs:Class ;
rdfs:label "synapsis maintenance defective" ;
rdfs:comment "Animals are unable to maintain paired chromosome throughout pachytene." ;
rdfs:subClassOf obo:WBPhenotype_0002012 .
obo:CHEBI_29214 a rdfs:Class ;
rdfs:label "sulfonic acid" ;
rdfs:subClassOf obo:CHEBI_33402 .
obo:GO_0042073 a rdfs:Class ;
rdfs:label "intraciliary transport" ;
rdfs:comment "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0010970 .
obo:GO_0045769 a rdfs:Class ;
rdfs:label "negative regulation of asymmetric cell division" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." ;
rdfs:subClassOf obo:GO_0009786 , obo:GO_0051782 , obo:GO_0065007 .
obo:CHEBI_33246 a rdfs:Class ;
rdfs:label "inorganic group" ;
rdfs:comment "Any substituent group which does not contain carbon." ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:WBbt_0003810 a rdfs:Class ;
rdfs:label "C" ;
rdfs:comment "Embryonic founder cell" ;
rdfs:subClassOf obo:WBbt_0008447 .
obo:GO_2000293 a rdfs:Class ;
rdfs:label "negative regulation of defecation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of defecation." ;
rdfs:subClassOf obo:GO_0051048 , obo:GO_0060457 , obo:GO_0065007 , obo:GO_2000292 .
obo:WBPhenotype_0002535 a rdfs:Class ;
rdfs:label "dye filling defect"@en ;
rdfs:comment "Animals exhibit variations in the extent to which one or more sensory neurons associated with sensilla (typically one or more amphids and/or phasmids) take up dye from the environment, compared to controls. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." ;
rdfs:subClassOf obo:WBPhenotype_0000255 .
obo:WBPhenotype_0000662 a rdfs:Class ;
rdfs:label "foraging behavior variant" ;
rdfs:comment "Variations in the behavior by which an organism locates food compared to control animals. In C. elegans roaming or dwelling activity on food are two examples of parameters used to assess this behavior. Roaming is defined as moving in a high-speed forward direction with brief backward movement, often traversing wide regions. Dwelling is defined as low-speed/high turning movement restricted to a confined region." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:WBPhenotype_0000068 a rdfs:Class ;
rdfs:label "cellular oxidative stress response variant" ;
rdfs:comment "Any variation in the state or activity of a cell (in terms of secretion, enzyme production, gene expression, etc.) in response to high levels of reactive oxygen species, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000142 , obo:WBPhenotype_0000523 , obo:WBPhenotype_0001620 .
obo:GO_2001244 a rdfs:Class ;
rdfs:label "positive regulation of intrinsic apoptotic signaling pathway" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902533 , obo:GO_2001235 , obo:GO_2001242 .
obo:WBPhenotype_0002034 a rdfs:Class ;
rdfs:label "lectin binding does not occur" ;
rdfs:comment "Animals are not observed to contain targets for exogenously applied lectins." ;
rdfs:subClassOf obo:WBPhenotype_0002031 .
obo:WBPhenotype_0002287 a rdfs:Class ;
rdfs:label "tail movement variant" ;
rdfs:comment "The most posterior portion of the animal exhibits variations in its movement compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001699 .
obo:WBPhenotype_0000719 a rdfs:Class ;
rdfs:label "obsolete reporter gene expression variant" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0001584 a rdfs:Class ;
rdfs:label "chromosome alignment variant" ;
rdfs:comment "Any variation in the movement of chromosomes to the spindle equator during mitosis compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000773 .
obo:GO_1902231 a rdfs:Class ;
rdfs:label "positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902229 , obo:GO_2001244 .
obo:WBPhenotype_0000982 a rdfs:Class ;
rdfs:label "spermatid maturation variant" ;
rdfs:comment "Animals exhibit variations in the ability of a relatively unspecialized spermatocyte to acquire the properties of a spermatid cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000670 .
obo:WBPhenotype_0000970 a rdfs:Class ;
rdfs:label "embryonic pigmentation variant" ;
rdfs:comment "Embryos exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals ." ;
rdfs:subClassOf obo:WBPhenotype_0001009 .
obo:GO_1903312 a rdfs:Class ;
rdfs:label "negative regulation of mRNA metabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051253 , obo:GO_0065007 , obo:GO_1903311 .
obo:CHEBI_35681 a rdfs:Class ;
rdfs:label "secondary alcohol" ;
rdfs:comment "A secondary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:WBPhenotype_0001416 a rdfs:Class ;
rdfs:label "pathogen adherence defect" ;
rdfs:comment "Pathogens are unable to adhere/colonize the surface of host animals. This defect is often associated with changes in cuticle surface properties of the host." ;
rdfs:subClassOf obo:WBPhenotype_0001014 , obo:WBPhenotype_0002461 .
obo:WBPhenotype_0001917 a rdfs:Class ;
rdfs:label "protein acetylation variant" ;
rdfs:comment "Variations in the processes that incorporate acetyl groups to one or more amino acids within a protein, compared to control. An acetyl group is CH3CO-." ;
rdfs:subClassOf obo:WBPhenotype_0001382 .
obo:WBls_0000015 a rdfs:Class ;
rdfs:label "elongating embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 350-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The stage that embryo starts elongation until elongation is over." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000805 .
obo:WBPhenotype_0002648 a rdfs:Class ;
rdfs:label "dendrite branching variant"@en ;
rdfs:comment "Animals display variations in the number or pattern of neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002647 .
obo:CHEBI_58001 a rdfs:Class ;
rdfs:label "primary aliphatic ammonium ion" ;
rdfs:comment "The conjugate acid of a primary aliphatic amine." ;
rdfs:subClassOf obo:CHEBI_65296 .
obo:WBPhenotype_0000613 a rdfs:Class ;
rdfs:label "reproductive system physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the reproductive system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000575 .
obo:GO_0040020 a rdfs:Class ;
rdfs:label "regulation of meiotic nuclear division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0051445 , obo:GO_0051783 , obo:GO_0065007 .
obo:GO_0005819 a rdfs:Class ;
rdfs:label "spindle" ;
rdfs:comment "The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart." ;
rdfs:subClassOf obo:GO_0043232 .
obo:WBPhenotype_0001286 a rdfs:Class ;
rdfs:label "food suppressed pumping variant" ;
rdfs:comment "Exposure to food does not reduce pharyngeal pumping to the same extent as observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001072 , obo:WBPhenotype_0001287 .
obo:WBbt_0005766 a rdfs:Class ;
rdfs:label "Anatomy" ;
rdfs:comment "entity of anatomical origin that is either entirely acellular or is a collection of cells and acellular parts." ;
rdfs:subClassOf obo:WBbt_0000100 .
obo:GO_0160313 a rdfs:Class ;
rdfs:label "endosomal intralumenal vesicle" ;
rdfs:comment "A membrane-bounded vesicle that is located within the lumen of an endosome." ;
rdfs:subClassOf obo:GO_0031410 , obo:GO_0097708 .
obo:WBPhenotype_0000042 a rdfs:Class ;
rdfs:label "slow embryonic development" ;
rdfs:comment "The progression through stages between fertilization to hatching are temporally retarded." ;
rdfs:subClassOf obo:WBPhenotype_0000674 , obo:WBPhenotype_0000749 .
obo:WBPhenotype_0001744 a rdfs:Class ;
rdfs:label "cell adhesion variant" ;
rdfs:comment "Any variation in the attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000519 , obo:WBPhenotype_0001657 .
obo:CHEBI_22314 a rdfs:Class ;
rdfs:label "alkali metal atom" ;
rdfs:subClassOf obo:CHEBI_33318 , obo:CHEBI_33521 , obo:CHEBI_33559 .
obo:WBbt_0008588 a rdfs:Class ;
rdfs:label "C lineage cell" ;
rdfs:comment "A cell that is the C blast cell or is a lineal descendant of C." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBPhenotype_0000179 a rdfs:Class ;
rdfs:label "neuron degeneration" ;
rdfs:comment "Cells specialized for receiving, conducting and transmitting impulses in the nervous system are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles." ;
rdfs:subClassOf obo:WBPhenotype_0000178 , obo:WBPhenotype_0000905 .
obo:WBPhenotype_0000969 a rdfs:Class ;
rdfs:label "accessory cell morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure, organization or placement of the cells that support sensory neurons, compared to that observed in control animals. In C. elegans, this category collectively refers to socket cells, sheath cells, and structural cells, or their processes." ;
rdfs:subClassOf obo:WBPhenotype_0000533 , obo:WBPhenotype_0000604 .
obo:WBPhenotype_0002259 a rdfs:Class ;
rdfs:label "dendritic termini number reduced" ;
rdfs:comment "The number of terminal regions of a neuron's dendrite is less that that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000882 .
obo:CHEBI_86992 a rdfs:Class ;
rdfs:label "(S)-fluoxetine" ;
rdfs:comment "An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine]." ;
rdfs:subClassOf obo:CHEBI_86990 .
obo:GO_0048646 a rdfs:Class ;
rdfs:label "anatomical structure formation involved in morphogenesis" ;
rdfs:comment "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ;
rdfs:subClassOf obo:GO_0032502 .
obo:WBPhenotype_0001604 a rdfs:Class ;
rdfs:label "mianserin resistant" ;
rdfs:comment "Animals fail to respond to the concentration of mianserin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001601 .
obo:PATO_0002055 a rdfs:Class ;
rdfs:label "increased fragility" ;
rdfs:comment "A fragility which is relatively high." ;
rdfs:subClassOf obo:PATO_0001362 , obo:PATO_0002305 .
obo:WBPhenotype_0002129 a rdfs:Class ;
rdfs:label "mitochondrial DNA copy number variant" ;
rdfs:comment "Relative levels of mtDNA differ from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000732 , obo:WBPhenotype_0001282 .
obo:CHEBI_6432 a rdfs:Class ;
rdfs:label "levamisole" ;
rdfs:comment "A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has S configuration. It is used (generally as the monohydrochloride salt) to treat parasitic worm infections in pigs, sheep and cattle and was formerly used in humans as an adjuvant to chemotherapy for the treatment of various cancers. It is also widely used as an adulterant to coccaine." ;
rdfs:subClassOf obo:CHEBI_77278 .
obo:WBPhenotype_0000566 a rdfs:Class ;
rdfs:label "ventral coiler" ;
rdfs:comment "A coiling body that bends ventrally." ;
rdfs:subClassOf obo:WBPhenotype_0000565 .
obo:CHEBI_22153 a rdfs:Class ;
rdfs:label "acaricide" ;
rdfs:comment "A substance used to destroy pests of the subclass Acari (mites and ticks)." ;
rdfs:subClassOf obo:CHEBI_25944 .
obo:CHEBI_36976 a rdfs:Class ;
rdfs:label "nucleotide" ;
rdfs:comment "A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid." ;
rdfs:subClassOf obo:CHEBI_25608 .
obo:CHEBI_38179 a rdfs:Class ;
rdfs:label "monocyclic heteroarene" ;
rdfs:subClassOf obo:CHEBI_33833 .
obo:WBPhenotype_0000105 a rdfs:Class ;
rdfs:label "oocyte meiotic maturation variant" ;
rdfs:comment "Variations in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal compared to control animals. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly." ;
rdfs:subClassOf obo:WBPhenotype_0000313 .
obo:CHEBI_16733 a rdfs:Class ;
rdfs:label "D-alpha-amino acid" ;
rdfs:subClassOf obo:CHEBI_83925 .
obo:CHEBI_237958 a rdfs:Class ;
rdfs:label "({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate" ;
rdfs:subClassOf obo:CHEBI_37045 , obo:CHEBI_37096 .
obo:WBbt_0005780 a rdfs:Class ;
rdfs:label "non-striated muscle" ;
rdfs:comment "Muscle cell that has either one or a few well-structured sarcomeres or myofilament networks that are less well organized." ;
rdfs:subClassOf obo:WBbt_0003675 .
obo:WBPhenotype_0001922 a rdfs:Class ;
rdfs:label "axonal transport variant" ;
rdfs:comment "Any variation in the directed movement of organelles or molecules along microtubules in nerve cell axons." ;
rdfs:subClassOf obo:WBPhenotype_0002563 .
obo:CHEBI_27027 a rdfs:Class ;
rdfs:label "micronutrient" ;
rdfs:comment "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." ;
rdfs:subClassOf obo:CHEBI_33284 .
obo:CHEBI_6015 a rdfs:Class ;
rdfs:label "isoflurane" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_37143 .
obo:WBPhenotype_0001337 a rdfs:Class ;
rdfs:label "adrenergic receptor antagonist response variant" ;
rdfs:comment "Animals exhibit variations in their response to a specific adrenergic receptor antagonist compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:CHEBI_36916 a rdfs:Class ;
rdfs:label "cation" ;
rdfs:comment "A monoatomic or polyatomic species having one or more elementary charges of the proton." ;
rdfs:subClassOf obo:CHEBI_24870 .
obo:CHEBI_30488 a rdfs:Class ;
rdfs:label "sulfonium" ;
rdfs:subClassOf obo:CHEBI_26830 , obo:CHEBI_33535 , obo:CHEBI_50313 .
obo:CHEBI_33694 a rdfs:Class ;
rdfs:label "biomacromolecule" ;
rdfs:comment "A macromolecule formed by a living organism." ;
rdfs:subClassOf obo:CHEBI_33839 , obo:CHEBI_50860 .
obo:WBPhenotype_0000116 a rdfs:Class ;
rdfs:label "mid larval lethal" ;
rdfs:comment "Animals die in between the early and late larval stages. In C. elegans, this occurs during the L2- L3 larval stages of the life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000054 .
obo:WBPhenotype_0002627 a rdfs:Class ;
rdfs:label "in vitro attachment to substrate abnormal"@en ;
rdfs:comment "Animals exhibit an abnormal attachment (or lack thereof) to a substrate in vitro, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002626 .
obo:WBPhenotype_0001881 a rdfs:Class ;
rdfs:label "endoplasmic reticulum symmetry variant early emb" ;
rdfs:comment "Any variation in the normally asymmetric distribution of the endoplasmic reticulum during cell divisions of the early embryo. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ;
rdfs:subClassOf obo:WBPhenotype_0001880 .
obo:CL_0000039 a rdfs:Class ;
rdfs:label "germ line cell" ;
rdfs:comment "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." ;
rdfs:subClassOf obo:CL_0000000 .
obo:WBPhenotype_0002509 a rdfs:Class ;
rdfs:label "extra dopaminergic neuron"@en ;
rdfs:comment "Animals produce an excess number of dopaminergic neurons compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002508 .
obo:GO_0033046 a rdfs:Class ;
rdfs:label "negative regulation of sister chromatid segregation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." ;
rdfs:subClassOf obo:GO_0033045 , obo:GO_0051985 , obo:GO_0065007 , obo:GO_2001251 .
obo:WBPhenotype_0000932 a rdfs:Class ;
rdfs:label "bisphenol A hypersensitive" ;
rdfs:comment "Animals respond to bisphenol A at a lower concentration or a shorter exposure time compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000931 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0001805 a rdfs:Class ;
rdfs:label "mitochondria vesiculated" ;
rdfs:comment "Inner membrane of mitochondria are disconnected and form vesicular bodies." ;
rdfs:subClassOf obo:WBPhenotype_0001401 .
obo:CHEBI_51026 a rdfs:Class ;
rdfs:label "macrocycle" ;
rdfs:comment "A cyclic compound containing nine or more atoms as part of the cyclic system." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:CHEBI_24873 a rdfs:Class ;
rdfs:label "iron molecular entity" ;
rdfs:subClassOf obo:CHEBI_33744 .
obo:WBPhenotype_0002401 a rdfs:Class ;
rdfs:label "excess fatty acids" ;
rdfs:comment "The concentration of fatty acids in the animal are greater than that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000138 .
obo:GO_0045596 a rdfs:Class ;
rdfs:label "negative regulation of cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0048523 , obo:GO_0051093 , obo:GO_0065007 .
obo:WBPhenotype_0000725 a rdfs:Class ;
rdfs:label "lipid metabolism variant" ;
rdfs:comment "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of lipid within the organism or cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:PATO_0000384 a rdfs:Class ;
rdfs:label "male" ;
rdfs:comment "A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes." ;
rdfs:subClassOf obo:PATO_0001894 .
obo:GO_0042401 a rdfs:Class ;
rdfs:label "biogenic amine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ;
rdfs:subClassOf obo:GO_0006576 , obo:GO_0009309 .
obo:WBPhenotype_0001669 a rdfs:Class ;
rdfs:label "presynaptic vesicle number variant" ;
rdfs:comment "Animals exhibit a variation in the ratio of synaptic vesicles per synapse of a neuron, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001321 , obo:WBPhenotype_0001332 .
obo:WBPhenotype_0002366 a rdfs:Class ;
rdfs:label "touch-induced suppression of head movement defective" ;
rdfs:comment "Animals do not suppress exploratory head movements in response to anterior touch stimuli, unlike control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:WBPhenotype_0001137 a rdfs:Class ;
rdfs:label "embryos small early emb" ;
rdfs:comment "Embryos are produced that are less than fifty percent of the size of control embryos." ;
rdfs:subClassOf obo:WBPhenotype_0000229 , obo:WBPhenotype_0001135 .
obo:GO_0009994 a rdfs:Class ;
rdfs:label "oocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0030154 .
obo:CHEBI_24870 a rdfs:Class ;
rdfs:label "ion" ;
rdfs:comment "A molecular entity having a net electric charge." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:WBPhenotype_0002446 a rdfs:Class ;
rdfs:label "pharyngeal pumping rate in response to light variant" ;
rdfs:comment "Animals exhibit variations in pharyngeal pumping rate in response to light, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001006 , obo:WBPhenotype_0001897 .
obo:GO_0010042 a rdfs:Class ;
rdfs:label "response to manganese ion" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus." ;
rdfs:subClassOf obo:GO_0010038 .
obo:GO_0090068 a rdfs:Class ;
rdfs:label "positive regulation of cell cycle process" ;
rdfs:comment "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0045787 , obo:GO_0065007 .
obo:WBPhenotype_0002466 a rdfs:Class ;
rdfs:label "RNA methylation variant" ;
rdfs:comment "Variations in the processes that incorporate methyl groups to one or more bases within RNA, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001827 .
obo:WBPhenotype_0000235 a rdfs:Class ;
rdfs:label "dopamine synthesis defective" ;
rdfs:comment "Animals are unable to carry out the chemical reactions and pathways resulting in the formation of dopamine." ;
rdfs:subClassOf obo:WBPhenotype_0000233 .
obo:GO_0140241 a rdfs:Class ;
rdfs:label "translation at synapse" ;
rdfs:comment "Translation that occurs at the synapse." ;
rdfs:subClassOf obo:GO_0006412 .
obo:CHEBI_61120 a rdfs:Class ;
rdfs:label "nucleobase-containing molecular entity" ;
rdfs:comment "Any compound that has a nucleobase as a part." ;
rdfs:subClassOf obo:CHEBI_33833 , obo:CHEBI_51143 .
obo:GO_0044842 a rdfs:Class ;
rdfs:label "gut granule lumen" ;
rdfs:comment "The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans." ;
rdfs:subClassOf obo:GO_0043233 , obo:GO_0070013 .
obo:WBls_0000037 a rdfs:Class ;
rdfs:label "L3-L4 molt Ce" ;
rdfs:comment "The stage when an animal shifts from L3 larva to L4 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000824 .
obo:CHEBI_63944 a rdfs:Class ;
rdfs:label "macrocyclic lactone" ;
rdfs:comment "Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule." ;
rdfs:subClassOf obo:CHEBI_25000 , obo:CHEBI_51026 .
obo:GO_1904146 a rdfs:Class ;
rdfs:label "positive regulation of meiotic cell cycle process involved in oocyte maturation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." ;
rdfs:subClassOf obo:GO_0051446 , obo:GO_0065007 , obo:GO_0090068 , obo:GO_1903538 .
obo:WBbt_0008599 a rdfs:Class ;
rdfs:label "G cell" ;
rdfs:comment "Ventral ganglion neuroblasts present at hatching, located near the excretory pore." ;
rdfs:subClassOf obo:WBbt_0006783 .
obo:GO_1902905 a rdfs:Class ;
rdfs:label "positive regulation of supramolecular fiber organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1902903 .
obo:GO_2000427 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic cell clearance" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance." ;
rdfs:subClassOf obo:GO_0050766 , obo:GO_0065007 , obo:GO_2000425 .
obo:GO_0099514 a rdfs:Class ;
rdfs:label "synaptic vesicle cytoskeletal transport" ;
rdfs:comment "The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors." ;
rdfs:subClassOf obo:GO_0048489 , obo:GO_0099518 .
obo:GO_0051932 a rdfs:Class ;
rdfs:label "synaptic transmission, GABAergic" ;
rdfs:comment "The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ;
rdfs:subClassOf obo:GO_0007268 .
obo:GO_0032229 a rdfs:Class ;
rdfs:label "negative regulation of synaptic transmission, GABAergic" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ;
rdfs:subClassOf obo:GO_0032228 , obo:GO_0050805 , obo:GO_0065007 .
obo:CHEBI_22985 a rdfs:Class ;
rdfs:label "calcium molecular entity" ;
rdfs:subClassOf obo:CHEBI_33299 .
obo:WBbt_0006849 a rdfs:Class ;
rdfs:label "germline precursor cell" ;
rdfs:comment "member of a set of two cells that generate exclusively sperm and ovum." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:CHEBI_48358 a rdfs:Class ;
rdfs:label "polar aprotic solvent" ;
rdfs:comment "A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds." ;
rdfs:subClassOf obo:CHEBI_48354 , obo:CHEBI_48357 .
obo:WBPhenotype_0001704 a rdfs:Class ;
rdfs:label "multiple alae" ;
rdfs:comment "Alae contain more cuticular ridges than control animals. In C. elegans alae are composed of three cuticular ridges." ;
rdfs:subClassOf obo:WBPhenotype_0001412 .
obo:GO_1901888 a rdfs:Class ;
rdfs:label "regulation of cell junction assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell junction assembly." ;
rdfs:subClassOf obo:GO_0044087 , obo:GO_0051128 , obo:GO_0065007 .
obo:CHEBI_33659 a rdfs:Class ;
rdfs:label "organic aromatic compound" ;
rdfs:subClassOf obo:CHEBI_33655 , obo:CHEBI_33832 .
obo:WBPhenotype_0000404 a rdfs:Class ;
rdfs:label "delayed hatching" ;
rdfs:comment "The emergence of larvae from their protective egg shells is retarded compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000048 , obo:WBPhenotype_0000438 .
obo:WBPhenotype_0001621 a rdfs:Class ;
rdfs:label "organism oxidative stress response hypersensitive" ;
rdfs:comment "Animals respond to a lower concentration of reactive oxygen species or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001620 .
obo:WBPhenotype_0001438 a rdfs:Class ;
rdfs:label "odorant positive chemotaxis defective" ;
rdfs:comment "Animals fail to move towards attractive volatile organic molecules. In C. elegans, these compounds are sensed by the AWA and AWC neurons." ;
rdfs:subClassOf obo:WBPhenotype_0000015 , obo:WBPhenotype_0000265 .
obo:CHEBI_35300 a rdfs:Class ;
rdfs:label "ortho- and peri-fused polycyclic arene" ;
rdfs:subClassOf obo:CHEBI_33639 , obo:CHEBI_33848 .
obo:CHEBI_28874 a rdfs:Class ;
rdfs:label "phosphatidylinositol" ;
rdfs:comment "Any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol." ;
rdfs:subClassOf obo:CHEBI_36315 .
obo:PATO_0000018 a rdfs:Class ;
rdfs:label "fluorescence" ;
rdfs:comment "A luminous flux quality inhering in a bearer by virtue of the bearer's emitting longer wavelength light following the absorption of shorter wavelength radiation; fluorescence is common with aromatic compounds with several rings joined together." ;
rdfs:subClassOf obo:PATO_0001296 .
obo:WBPhenotype_0000572 a rdfs:Class ;
rdfs:label "neuronal outgrowth variant" ;
rdfs:comment "Any variation in the processes that govern the extension of neuronal projections." ;
rdfs:subClassOf obo:WBPhenotype_0000816 .
obo:GO_1905133 a rdfs:Class ;
rdfs:label "negative regulation of meiotic chromosome separation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905132 , obo:GO_1905819 , obo:GO_2000242 .
obo:GO_0031109 a rdfs:Class ;
rdfs:label "microtubule polymerization or depolymerization" ;
rdfs:comment "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." ;
rdfs:subClassOf obo:GO_0000226 .
obo:CHEBI_37206 a rdfs:Class ;
rdfs:label "hexol" ;
rdfs:comment "A polyol that contains 6 hydroxy groups." ;
rdfs:subClassOf obo:CHEBI_26191 .
obo:GO_2000748 a rdfs:Class ;
rdfs:label "positive regulation of defecation rhythm" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of defecation rhythm." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000294 , obo:GO_2000746 .
obo:CHEBI_64272 a rdfs:Class ;
rdfs:label "tunicamycin D2" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 15-methylhexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:GO_0051962 a rdfs:Class ;
rdfs:label "positive regulation of nervous system development" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0051960 , obo:GO_0065007 .
obo:WBPhenotype_0002434 a rdfs:Class ;
rdfs:label "mitochondrial stress response variant" ;
rdfs:comment "Animals exhibit variations in their response to mitochondrial stress, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000142 .
obo:WBPhenotype_0001840 a rdfs:Class ;
rdfs:label "response to injury variant" ;
rdfs:comment "Variations in the processes that restore integrity to a damaged tissue following an injury, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000142 .
obo:WBPhenotype_0002108 a rdfs:Class ;
rdfs:label "cell type morphology variant" ;
rdfs:comment "Any variation in the form or composition of specialized cell types, compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
rdfs:subClassOf obo:WBPhenotype_0000533 .
obo:CHEBI_31206 a rdfs:Class ;
rdfs:label "ammonium chloride" ;
rdfs:comment "An inorganic chloride having ammonium as the counterion." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_36093 , obo:CHEBI_47704 .
obo:WBPhenotype_0001264 a rdfs:Class ;
rdfs:label "peroxisome physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the peroxisome to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 .
obo:GO_0006914 a rdfs:Class ;
rdfs:label "autophagy" ;
rdfs:comment "The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0061919 .
obo:WBPhenotype_0001729 a rdfs:Class ;
rdfs:label "mating plug produced" ;
rdfs:comment "Males form copulatory mating plugs." ;
rdfs:subClassOf obo:WBPhenotype_0001728 .
obo:WBPhenotype_0000132 a rdfs:Class ;
rdfs:label "pheromone induced dauer formation variant" ;
rdfs:comment "Animals exhibit variations in the entry into the dauer stage when exposed to concentrations of chemicals that induce dauer formation in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001539 .
obo:GO_2000197 a rdfs:Class ;
rdfs:label "regulation of ribonucleoprotein complex localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization." ;
rdfs:subClassOf obo:GO_0060341 , obo:GO_0065007 .
obo:CHEBI_20706 a rdfs:Class ;
rdfs:label "6-aminopurines" ;
rdfs:comment "Any compound having 6-aminopurine (adenine) as part of its structure." ;
rdfs:subClassOf obo:CHEBI_22527 .
obo:CHEBI_17544 a rdfs:Class ;
rdfs:label "hydrogencarbonate" ;
rdfs:comment "The carbon oxoanion resulting from the removal of a proton from carbonic acid." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35604 .
obo:WBPhenotype_0001870 a rdfs:Class ;
rdfs:label "meiotic spindle rotation defective" ;
rdfs:comment "Cells undergoing meiosis exhibit defects in the rotation of the meiotic spindle." ;
rdfs:subClassOf obo:WBPhenotype_0001868 .
obo:GO_1905818 a rdfs:Class ;
rdfs:label "regulation of chromosome separation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of chromosome separation." ;
rdfs:subClassOf obo:GO_0051983 , obo:GO_0065007 .
obo:PATO_0000516 a rdfs:Class ;
rdfs:label "sensitive toward" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's having sensitivity toward an external stimulus." ;
rdfs:subClassOf obo:PATO_0000085 .
obo:CHEBI_23377 a rdfs:Class ;
rdfs:label "copper molecular entity" ;
rdfs:subClassOf obo:CHEBI_33745 .
obo:GO_0010648 a rdfs:Class ;
rdfs:label "negative regulation of cell communication" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0048523 , obo:GO_0065007 .
obo:GO_0031974 a rdfs:Class ;
rdfs:label "membrane-enclosed lumen" ;
rdfs:comment "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0001321 a rdfs:Class ;
rdfs:label "presynaptic region morphology variant" ;
rdfs:comment "Animals display variations in the structure, configuration, distribution or ratio of the components of the vesicle-filled varicosities of the synapse compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000616 .
obo:CHEBI_33582 a rdfs:Class ;
rdfs:label "carbon group molecular entity" ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:WBPhenotype_0002574 a rdfs:Class ;
rdfs:label "gene expression level variation abnormal"@en ;
rdfs:comment "Animals exhibit abnormal amounts of variation in gene expression level between individual animals, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:WBPhenotype_0001371 a rdfs:Class ;
rdfs:label "protein RNA interaction variant" ;
rdfs:comment "Variations in the selective and non-covalent physical association between a protein and a specific RNA sequence, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001369 .
obo:CHEBI_33653 a rdfs:Class ;
rdfs:label "aliphatic compound" ;
rdfs:comment "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:GO_0043254 a rdfs:Class ;
rdfs:label "regulation of protein-containing complex assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein complex assembly." ;
rdfs:subClassOf obo:GO_0044087 , obo:GO_0051128 , obo:GO_0065007 .
obo:WBbt_0005135 a rdfs:Class ;
rdfs:label "head ganglion" ;
rdfs:comment "ganglion in the head." ;
rdfs:subClassOf obo:WBbt_0005189 .
obo:WBPhenotype_0000889 a rdfs:Class ;
rdfs:label "sexually dimorphic physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required to carry out sex-specific activities or to be able to perceive and respond to sex-specific stimuli compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000576 .
obo:WBPhenotype_0001911 a rdfs:Class ;
rdfs:label "axon regeneration defective" ;
rdfs:comment "Animals do not regrow axons following axon loss or damage, to the same extent, or in the same manner as observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000880 .
obo:WBPhenotype_0001528 a rdfs:Class ;
rdfs:label "sensillum accessory cell morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of any component of the sensillum channel including the sheath and or socket cells, their junctions with each other, channel neurons or surrounding epithelia compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000299 .
obo:CHEBI_51061 a rdfs:Class ;
rdfs:label "hormone receptor modulator" ;
rdfs:comment "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." ;
rdfs:subClassOf obo:CHEBI_90710 .
obo:WBPhenotype_0000776 a rdfs:Class ;
rdfs:label "passage through meiosis defective early emb" ;
rdfs:comment "Male and female PNs not visible; embryo often fills egg shell completely." ;
rdfs:subClassOf obo:WBPhenotype_0001041 .
obo:CHEBI_24848 a rdfs:Class ;
rdfs:label "inositol" ;
rdfs:comment "Any cyclohexane-1,2,3,4,5,6-hexol." ;
rdfs:subClassOf obo:CHEBI_23451 , obo:CHEBI_37206 .
obo:PATO_0000688 a rdfs:Class ;
rdfs:label "asynchronous" ;
rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's not occurring or existing at the same time or having the same period or phase." ;
rdfs:subClassOf obo:PATO_0000057 .
obo:GO_0004104 a rdfs:Class ;
rdfs:label "cholinesterase activity" ;
rdfs:comment "Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion." ;
rdfs:subClassOf obo:GO_0052689 .
obo:GO_0010605 a rdfs:Class ;
rdfs:label "negative regulation of macromolecule metabolic process" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0060255 , obo:GO_0065007 .
obo:GO_1903599 a rdfs:Class ;
rdfs:label "positive regulation of autophagy of mitochondrion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy." ;
rdfs:subClassOf obo:GO_0010508 , obo:GO_0065007 , obo:GO_1903146 .
obo:WBPhenotype_0000411 a rdfs:Class ;
rdfs:label "rod like larval lethal" ;
rdfs:comment "Animals die as rigid, rod-like larva. In C. elegans this defect is often caused by the misspecification of the excretory duct cell." ;
rdfs:subClassOf obo:WBPhenotype_0000035 , obo:WBPhenotype_0000054 .
obo:GO_0046889 a rdfs:Class ;
rdfs:label "positive regulation of lipid biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0045834 , obo:GO_0046890 , obo:GO_0065007 .
obo:WBPhenotype_0002146 a rdfs:Class ;
rdfs:label "small RNA germline expression variant" ;
rdfs:comment "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in the germline. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs)." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:WBPhenotype_0001449 a rdfs:Class ;
rdfs:label "aqueous negative chemotaxis defective" ;
rdfs:comment "Animals fail to move away from repellent water soluble chemicals." ;
rdfs:subClassOf obo:WBPhenotype_0001450 .
obo:GO_0044772 a rdfs:Class ;
rdfs:label "mitotic cell cycle phase transition" ;
rdfs:comment "The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase." ;
rdfs:subClassOf obo:GO_0044770 , obo:GO_1903047 .
obo:WBPhenotype_0002225 a rdfs:Class ;
rdfs:label "lead hypersensitive" ;
rdfs:comment "Animals respond to lead at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001918 , obo:WBPhenotype_0002227 .
obo:GO_0120305 a rdfs:Class ;
rdfs:label "regulation of pigmentation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:WBPhenotype_0000909 a rdfs:Class ;
rdfs:label "pharyngeal intestinal valve morphology variant" ;
rdfs:comment "Any variation in the structure or appearance of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000598 .
obo:CHEBI_63409 a rdfs:Class ;
rdfs:label "pentose derivative" ;
rdfs:comment "A monosaccharide derivative that is formally obtained from a pentose." ;
rdfs:subClassOf obo:CHEBI_63367 .
obo:WBPhenotype_0001310 a rdfs:Class ;
rdfs:label "neuron positioning variant" ;
rdfs:comment "The placement of neuronal cells, as a whole or of a specific class of neuron in the animal, deviates from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000604 , obo:WBPhenotype_0002552 .
obo:GO_0010470 a rdfs:Class ;
rdfs:label "regulation of gastrulation" ;
rdfs:comment "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0045995 , obo:GO_0065007 .
obo:WBPhenotype_0002329 a rdfs:Class ;
rdfs:label "obsolete temporal frequency of sinusoidal movement variant" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0001610 a rdfs:Class ;
rdfs:label "diethyl ether hypersensitive" ;
rdfs:comment "Animals respond to the anesthetic ether at lower concentrations or shorter response times than control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000008 , obo:WBPhenotype_0001918 .
obo:GO_0032535 a rdfs:Class ;
rdfs:label "regulation of cellular component size" ;
rdfs:comment "A process that modulates the size of a cellular component." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0090066 .
obo:WBbt_0005732 a rdfs:Class ;
rdfs:label "extracellular component" ;
rdfs:comment "Anatomical structures that exist outside of cells; non-cellular." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:GO_0007268 a rdfs:Class ;
rdfs:label "chemical synaptic transmission" ;
rdfs:comment "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ;
rdfs:subClassOf obo:GO_0098916 .
obo:WBbt_0006799 a rdfs:Class ;
rdfs:label "spermatocyte" ;
rdfs:comment "A cell which gives rise to spermatids by meiosis." ;
rdfs:subClassOf obo:WBbt_0006796 .
obo:WBPhenotype_0000004 a rdfs:Class ;
rdfs:label "constitutive egg laying" ;
rdfs:comment "Eggs are laid under conditions where egg laying is normally inhibited." ;
rdfs:subClassOf obo:WBPhenotype_0000005 .
obo:GO_0048675 a rdfs:Class ;
rdfs:label "axon extension" ;
rdfs:comment "Long distance growth of a single axon process involved in cellular development." ;
rdfs:subClassOf obo:GO_1990138 .
obo:CHEBI_39214 a rdfs:Class ;
rdfs:label "abamectin" ;
rdfs:comment "Mixture of 80% avermectin B1a and 20% avermectin B1b." ;
rdfs:subClassOf obo:CHEBI_39213 , obo:CHEBI_39219 , obo:CHEBI_60004 .
obo:GO_1904115 a rdfs:Class ;
rdfs:label "axon cytoplasm" ;
rdfs:comment "Any cytoplasm that is part of a axon." ;
rdfs:subClassOf obo:GO_0005737 , obo:GO_0120111 .
obo:GO_0070130 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial translation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ;
rdfs:subClassOf obo:GO_0017148 , obo:GO_0065007 , obo:GO_0070129 .
obo:WBPhenotype_0000765 a rdfs:Class ;
rdfs:label "spindle elongation integrity defective early emb" ;
rdfs:comment "The embryos exhibit defects in the cell cycle process whereby the distance is lengthened between poles of the spindle." ;
rdfs:subClassOf obo:WBPhenotype_0001102 .
obo:WBPhenotype_0000075 a rdfs:Class ;
rdfs:label "cuticle attachment variant" ;
rdfs:comment "Any variation in the attachment of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) to the outer body of an animal compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000201 .
obo:GO_0005739 a rdfs:Class ;
rdfs:label "mitochondrion" ;
rdfs:comment "A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." ;
rdfs:subClassOf obo:GO_0043231 .
obo:CHEBI_61293 a rdfs:Class ;
rdfs:label "adenyl nucleotide" ;
rdfs:comment "A nucleotide having adenine as the base." ;
rdfs:subClassOf obo:CHEBI_26395 .
obo:WBPhenotype_0002484 a rdfs:Class ;
rdfs:label "membrane fluidity variant"@en ;
rdfs:comment "Animals exhibit variations in fluidity of cell membranes, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001965 .
obo:GO_0007617 a rdfs:Class ;
rdfs:label "mating behavior" ;
rdfs:comment "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." ;
rdfs:subClassOf obo:GO_0019098 .
obo:WBPhenotype_0000194 a rdfs:Class ;
rdfs:label "first polar body position variant" ;
rdfs:comment "Variations in the placement of the polar body formed in the first division of meiosis of a primary oocyte, compared to control. A polar body is the by-product of meiosis (destined to degenerate) in female or hermaphrodite animals." ;
rdfs:subClassOf obo:WBPhenotype_0000775 .
obo:GO_0051234 a rdfs:Class ;
rdfs:label "establishment of localization" ;
rdfs:comment "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." ;
rdfs:subClassOf obo:GO_0051179 .
obo:WBbt_0005671 a rdfs:Class ;
rdfs:label "AWB" ;
rdfs:comment "Neuron class of two ciliated neurons with flattened, sheet-like endings that are associated with the sheath cells of the amphid sensilla" ;
rdfs:subClassOf obo:WBbt_0005394 , obo:WBbt_0005839 .
obo:CHEBI_16133 a rdfs:Class ;
rdfs:label "cyclopentanol" ;
rdfs:comment "The simplest member of the class of cyclopentanols bearing a single hydroxy substituent. The parent of the class of cyclopentanols." ;
rdfs:subClassOf obo:CHEBI_23495 .
obo:WBPhenotype_0000841 a rdfs:Class ;
rdfs:label "Z1 male lineage variant" ;
rdfs:comment "Z1 descendents exhibit altered developmental programs in the male compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000838 .
obo:CHEBI_27638 a rdfs:Class ;
rdfs:label "cobalt atom" ;
rdfs:comment "A cobalt group element atom that has atomic number 27." ;
rdfs:subClassOf obo:CHEBI_33358 , obo:CHEBI_88184 .
obo:CHEBI_15734 a rdfs:Class ;
rdfs:label "primary alcohol" ;
rdfs:comment "A primary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:CHEBI_33434 a rdfs:Class ;
rdfs:label "elemental halogen" ;
rdfs:subClassOf obo:CHEBI_33259 .
obo:GO_0048259 a rdfs:Class ;
rdfs:label "regulation of receptor-mediated endocytosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." ;
rdfs:subClassOf obo:GO_0030100 , obo:GO_0065007 .
obo:GO_0032096 a rdfs:Class ;
rdfs:label "negative regulation of response to food" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus." ;
rdfs:subClassOf obo:GO_0032095 , obo:GO_0032108 , obo:GO_0065007 .
obo:GO_0090327 a rdfs:Class ;
rdfs:label "negative regulation of locomotion involved in locomotory behavior" ;
rdfs:comment "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ;
rdfs:subClassOf obo:GO_0040013 , obo:GO_0048521 , obo:GO_0065007 , obo:GO_0090325 .
obo:CHEBI_37955 a rdfs:Class ;
rdfs:label "H1-receptor antagonist" ;
rdfs:comment "H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine." ;
rdfs:subClassOf obo:CHEBI_37956 .
obo:WBPhenotype_0001696 a rdfs:Class ;
rdfs:label "biosynthesis variant" ;
rdfs:comment "Animals exhibit variations in the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000463 .
obo:CHEBI_39208 a rdfs:Class ;
rdfs:label "antibiotic insecticide" ;
rdfs:subClassOf obo:CHEBI_24852 , obo:CHEBI_39215 .
obo:WBbt_0005755 a rdfs:Class ;
rdfs:label "cuticle" ;
rdfs:comment "a rigid external coating which is secreted by the hypodermis, seam and some transitional epithelial cells which covers the outer body, the major openings into the body cavity from the exterior, and two large sensory bristles, the male spicules. The cuticle of the spicules, the hook, and of some portions of the spicule channels is especially rigid and is probably sclerotized. Similar sclerotic features are occasionally noted in the ventral surface of the male tail fan." ;
rdfs:subClassOf obo:WBbt_0005732 .
obo:WBPhenotype_0000620 a rdfs:Class ;
rdfs:label "excretory secretory system development variant" ;
rdfs:comment "Any variation in the progression of the excretory secretory system over time, from its formation to its mature state compared to control. The excretory secretory system consists of the excretory system and its associated glands." ;
rdfs:subClassOf obo:WBPhenotype_0000530 .
obo:WBPhenotype_0002372 a rdfs:Class ;
rdfs:label "presynaptic vesicle morphology altered" ;
rdfs:comment "Vesicles in the presynaptic terminal differ in size, shape, or composition from those observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001323 .
obo:GO_0048468 a rdfs:Class ;
rdfs:label "cell development" ;
rdfs:comment "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048869 .
obo:GO_0006900 a rdfs:Class ;
rdfs:label "vesicle budding from membrane" ;
rdfs:comment "The evagination of a membrane, resulting in formation of a vesicle." ;
rdfs:subClassOf obo:GO_0016050 , obo:GO_0061024 .
obo:PATO_0000050 a rdfs:Class ;
rdfs:label "life span" ;
rdfs:comment "A time quality inhering in a bearer by virtue of the bearer's expected maximum age." ;
rdfs:subClassOf obo:PATO_0000165 .
obo:WBPhenotype_0002186 a rdfs:Class ;
rdfs:label "cell fate transformation to pharyngeal muscle" ;
rdfs:comment "Animals develop pharyngeal muscles from precursor cells that do not normally produce pharyngeal muscles." ;
rdfs:subClassOf obo:WBPhenotype_0000414 .
obo:WBPhenotype_0000460 a rdfs:Class ;
rdfs:label "paraquat response variant" ;
rdfs:comment "Animals exhibit variations in their response to paraquat compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000459 , obo:WBPhenotype_0000523 , obo:WBPhenotype_0001620 .
obo:GO_1903468 a rdfs:Class ;
rdfs:label "positive regulation of DNA replication initiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication." ;
rdfs:subClassOf obo:GO_0032298 , obo:GO_0065007 , obo:GO_1903465 , obo:GO_1903466 .
obo:PATO_0001442 a rdfs:Class ;
rdfs:label "wholeness" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of whether the bearer includes all its components." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:WBPhenotype_0002160 a rdfs:Class ;
rdfs:label "intraflagellar transport complex destabilized" ;
rdfs:comment "The intracellular complex of proteins that participates in bidirectional transport of molecules (cargo) along axonemal microtubules is not made up of or does not maintain the proper number or ratio of components as found in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002132 .
obo:CHEBI_29337 a rdfs:Class ;
rdfs:label "azanide" ;
rdfs:subClassOf obo:CHEBI_35106 , obo:CHEBI_79389 .
obo:WBPhenotype_0002153 a rdfs:Class ;
rdfs:label "dsRNA processing defective" ;
rdfs:comment "The production of silencing RNA from dsRNA is significantly deficient compared to controls. Deficiencies in this process can result in a defective RNAi response compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000028 .
obo:WBPhenotype_0000878 a rdfs:Class ;
rdfs:label "chemosensory neuron development variant" ;
rdfs:comment "Any variation in the progression of a chemosensory neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000816 .
obo:GO_0045184 a rdfs:Class ;
rdfs:label "establishment of protein localization" ;
rdfs:comment "The directed movement of a protein to a specific location." ;
rdfs:subClassOf obo:GO_0051234 .
obo:GO_0048858 a rdfs:Class ;
rdfs:label "cell projection morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a cell projection are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0030030 .
obo:GO_0005923 a rdfs:Class ;
rdfs:label "bicellular tight junction" ;
rdfs:comment "An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes." ;
rdfs:subClassOf obo:GO_0070160 .
obo:CHEBI_36860 a rdfs:Class ;
rdfs:label "14-hydroxy steroid" ;
rdfs:subClassOf obo:CHEBI_35350 .
obo:CHEBI_59163 a rdfs:Class ;
rdfs:label "biomarker" ;
rdfs:comment "A substance used as an indicator of a biological state." ;
rdfs:subClassOf obo:CHEBI_47867 .
obo:GO_0010549 a rdfs:Class ;
rdfs:label "regulation of membrane disassembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of membrane disassembly." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:WBPhenotype_0001941 a rdfs:Class ;
rdfs:label "rachis narrow" ;
rdfs:comment "The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001940 .
obo:GO_0048731 a rdfs:Class ;
rdfs:label "system development" ;
rdfs:comment "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_50906 a rdfs:Class ;
rdfs:label "role" ;
rdfs:comment "A role is particular behaviour which a material entity may exhibit." .
obo:WBPhenotype_0001968 a rdfs:Class ;
rdfs:label "somatic gonad precursor symmetrical sisters" ;
rdfs:comment "All somatic gonad precursor (SGP) daughters adopt a proximal fate resulting in an increase in the number of AC precursor cells at the expense of distal tip cells (DTC), which are thereby absent." ;
rdfs:subClassOf obo:WBPhenotype_0000399 , obo:WBPhenotype_0001235 .
obo:GO_0050918 a rdfs:Class ;
rdfs:label "positive chemotaxis" ;
rdfs:comment "The directed movement of a motile cell or organism towards a higher concentration of a chemical." ;
rdfs:subClassOf obo:GO_0006935 .
obo:WBPhenotype_0000997 a rdfs:Class ;
rdfs:label "cryophilic" ;
rdfs:comment "Animals tend to track and stay within low temperature environments." ;
rdfs:subClassOf obo:WBPhenotype_0000478 .
obo:WBPhenotype_0001044 a rdfs:Class ;
rdfs:label "cortical dynamics defective early emb" ;
rdfs:comment "Little/no cortical ruffling or pseudocleavage furrow, or excessive cortical activity. In C. elegans, this is often characterized at the two-cell stage." ;
rdfs:subClassOf obo:WBPhenotype_0000764 , obo:WBPhenotype_0001100 .
obo:WBPhenotype_0002236 a rdfs:Class ;
rdfs:label "endo lysosomal degradation pathway defective" ;
rdfs:comment "The degradation of endocytosed and intracellular material does not occur to the same extent as it does in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000585 .
obo:GO_0090316 a rdfs:Class ;
rdfs:label "positive regulation of intracellular protein transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0033157 , obo:GO_0051222 , obo:GO_0065007 .
obo:GO_0019226 a rdfs:Class .
obo:WBPhenotype_0002193 a rdfs:Class ;
rdfs:label "posterior reversed vulval lineage" ;
rdfs:comment "The orientation of the progeny of P7.p mimic those of P5.p and face towards the posterior of the worm, a phenotype referred to as posterior-reversed vulval lineage (P-Rvl)." ;
rdfs:subClassOf obo:WBPhenotype_0000220 , obo:WBPhenotype_0000239 .
obo:GO_2000171 a rdfs:Class ;
rdfs:label "negative regulation of dendrite development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development." ;
rdfs:subClassOf obo:GO_0010977 , obo:GO_0050773 , obo:GO_0051093 , obo:GO_0065007 .
obo:WBPhenotype_0000228 a rdfs:Class ;
rdfs:label "spontaneous mutation rate increased" ;
rdfs:comment "Animals accumulate a greater number of genetic lesions than control animals in the absence of an externally controlled mutagen. In C. elegans, this is often measured by observing the number of reversion events of a known mutant gene function over a couple generations." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:WBPhenotype_0000736 a rdfs:Class ;
rdfs:label "autophagy variant" ;
rdfs:comment "Animals exhibit variations in the process by which their cells digest parts of their own cytoplasm, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000585 .
obo:WBPhenotype_0001658 a rdfs:Class ;
rdfs:label "intercellular junction variant" ;
rdfs:comment "Animals exhibit variations in the specialized region of connection between two cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001657 .
obo:PATO_0002304 a rdfs:Class ;
rdfs:label "increased process quality" ;
rdfs:comment "A quality of a process that has a value that is increased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0001236 , obo:PATO_0002300 .
obo:WBPhenotype_0002311 a rdfs:Class ;
rdfs:label "turning variant" ;
rdfs:comment "Variations in the behavior by which an organism alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." ;
rdfs:subClassOf obo:WBPhenotype_0001702 .
obo:WBPhenotype_0001055 a rdfs:Class ;
rdfs:label "bromide chemotaxis defective" ;
rdfs:comment "Animals fail to exhibit the same taxis behavior as control animals in response to bromide. In C. elegans, this is characterized by the failure to move towards bromide." ;
rdfs:subClassOf obo:WBPhenotype_0001439 , obo:WBPhenotype_0001457 .
obo:WBPhenotype_0001675 a rdfs:Class ;
rdfs:label "male gonad development variant" ;
rdfs:comment "Males exhibit variations in the reproductive system, from its formation to the mature structure compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000613 , obo:WBPhenotype_0000691 .
obo:GO_2000253 a rdfs:Class ;
rdfs:label "positive regulation of feeding behavior" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of feeding behavior." ;
rdfs:subClassOf obo:GO_0048520 , obo:GO_0060259 , obo:GO_0065007 .
obo:GO_0120033 a rdfs:Class ;
rdfs:label "negative regulation of plasma membrane bounded cell projection assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly." ;
rdfs:subClassOf obo:GO_0031345 , obo:GO_0065007 , obo:GO_0120032 .
obo:WBPhenotype_0002638 a rdfs:Class ;
rdfs:label "increased susceptibility to oomycete infection"@en ;
rdfs:comment "Animals are more prone to infection, sickness and/or death caused by oomycete pathogens compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001013 .
obo:GO_0051983 a rdfs:Class ;
rdfs:label "regulation of chromosome segregation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0065007 .
obo:GO_0051336 a rdfs:Class ;
rdfs:label "regulation of hydrolase activity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." ;
rdfs:subClassOf obo:GO_0050790 , obo:GO_0065007 .
obo:WBPhenotype_0001263 a rdfs:Class ;
rdfs:label "peroxisome morphology variant" ;
rdfs:comment "The morphological appearance of peroxisomes is variant compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002089 .
obo:WBPhenotype_0000420 a rdfs:Class ;
rdfs:label "levamisole hypersensitive" ;
rdfs:comment "Animals respond to levamisole at a lower concentration or a shorter exposure compared to control animals. Levamisole is a cholinergic agonist." ;
rdfs:subClassOf obo:WBPhenotype_0000845 , obo:WBPhenotype_0001579 , obo:WBPhenotype_0001918 .
obo:GO_0040004 a rdfs:Class ;
rdfs:label "collagen and cuticulin-based cuticle attachment to epithelium" ;
rdfs:comment "Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans." ;
rdfs:subClassOf obo:GO_0022404 .
obo:WBPhenotype_0001401 a rdfs:Class ;
rdfs:label "mitochondria morphology variant" ;
rdfs:comment "The morphological appearance of mitochondria is varied compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002089 .
obo:WBPhenotype_0001084 a rdfs:Class ;
rdfs:label "sodium chloride chemotaxis defective" ;
rdfs:comment "Failure to execute characteristic response to sodium chloride compared to control. In C. elegans, animals move towards attractive concentrations of sodium chloride." ;
rdfs:subClassOf obo:WBPhenotype_0001441 , obo:WBPhenotype_0001462 .
obo:WBPhenotype_0002120 a rdfs:Class ;
rdfs:label "mitochondrial DNA repair variant" ;
rdfs:comment "Any variation in the process of restoring mitochondrial DNA after damage." ;
rdfs:subClassOf obo:WBPhenotype_0001938 .
obo:WBPhenotype_0001128 a rdfs:Class ;
rdfs:label "EMS anterior extension extreme early emb" ;
rdfs:comment "EMS extends too far anteriorly at the four cell stage." ;
rdfs:subClassOf obo:WBPhenotype_0001118 .
obo:CHEBI_39124 a rdfs:Class ;
rdfs:label "calcium ion" ;
rdfs:subClassOf obo:CHEBI_25213 , obo:CHEBI_35155 .
obo:CHEBI_76775 a rdfs:Class ;
rdfs:label "EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor" ;
rdfs:comment "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*)." ;
rdfs:subClassOf obo:CHEBI_76760 .
obo:CHEBI_17051 a rdfs:Class ;
rdfs:label "fluoride" ;
rdfs:subClassOf obo:CHEBI_16042 , obo:CHEBI_36895 .
obo:WBPhenotype_0001737 a rdfs:Class ;
rdfs:label "aqueous compound discrimination defective" ;
rdfs:comment "Animals are unable to locate the gradient peak of a water soluble compound, which was generated on a uniform concentration of another compound." ;
rdfs:subClassOf obo:WBPhenotype_0001443 .
obo:GO_0000226 a rdfs:Class ;
rdfs:label "microtubule cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." ;
rdfs:subClassOf obo:GO_0007010 , obo:GO_0007017 .
obo:GO_0050919 a rdfs:Class ;
rdfs:label "negative chemotaxis" ;
rdfs:comment "The directed movement of a motile cell or organism towards a lower concentration of a chemical." ;
rdfs:subClassOf obo:GO_0006935 .
obo:PATO_0002017 a rdfs:Class ;
rdfs:label "increased magnitude" ;
rdfs:subClassOf obo:PATO_0002016 .
obo:WBPhenotype_0001971 a rdfs:Class ;
rdfs:label "germ cell compartment anucleate" ;
rdfs:comment "Germ cell compartments do not contain a nucleus." ;
rdfs:subClassOf obo:WBPhenotype_0001970 .
obo:GO_0032224 a rdfs:Class ;
rdfs:label "positive regulation of synaptic transmission, cholinergic" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ;
rdfs:subClassOf obo:GO_0032222 , obo:GO_0050806 , obo:GO_0065007 .
obo:GO_0044237 a rdfs:Class ;
rdfs:label "obsolete cellular metabolic process" ;
rdfs:comment "OBSOLETE. The chemical reactions and pathways by which individual cells transform chemical substances." .
obo:WBPhenotype_0001095 a rdfs:Class ;
rdfs:label "organism high sodium chloride hypersensitive" ;
rdfs:comment "Animals respond to sodium chloride at a lower concentration or a shorter exposure compared to control animals. In C. elegans, this is often assayed through generation time and progeny number." ;
rdfs:subClassOf obo:WBPhenotype_0000876 , obo:WBPhenotype_0001918 .
obo:CHEBI_18310 a rdfs:Class ;
rdfs:label "alkane" ;
rdfs:comment "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms." ;
rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_33653 .
obo:CHEBI_79314 a rdfs:Class ;
rdfs:label "flame retardant" ;
rdfs:comment "Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_0044058 a rdfs:Class ;
rdfs:label "regulation of digestive system process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0044057 , obo:GO_0065007 .
obo:GO_1903147 a rdfs:Class ;
rdfs:label "negative regulation of autophagy of mitochondrion" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy." ;
rdfs:subClassOf obo:GO_0010507 , obo:GO_0065007 , obo:GO_1903146 .
obo:GO_0048511 a rdfs:Class ;
rdfs:label "rhythmic process" ;
rdfs:comment "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." ;
rdfs:subClassOf obo:GO_0008150 .
obo:WBPhenotype_0002644 a rdfs:Class ;
rdfs:label "precipice response variant"@en ;
rdfs:comment "Animals do not respond to the edge or gap in the medium surface they were supported on in the same manner as controls. In Mitchell et al., the precipice response was defined to be that within 2 seconds of the nose moving off the edge of the agar chunk, the worm begins a reversal that completes at least one full sine wave." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:WBPhenotype_0001798 a rdfs:Class ;
rdfs:label "inhibition of synaptogenesis defective" ;
rdfs:comment "The processes that inhibit the location or frequency of formation of synapses are downregulated resulting in the formation of synapses or synapse-like structures in areas of the neuron that are typically devoid of synapses in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000625 , obo:WBPhenotype_0000944 .
obo:WBPhenotype_0000867 a rdfs:Class ;
rdfs:label "embryonic arrest" ;
rdfs:comment "Cessation of development during any stage occurring after fertilization and until hatching compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:GO_0061982 a rdfs:Class ;
rdfs:label "meiosis I cell cycle process" ;
rdfs:comment "A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs." ;
rdfs:subClassOf obo:GO_1903046 .
obo:CHEBI_50316 a rdfs:Class ;
rdfs:label "bromonium" ;
rdfs:subClassOf obo:CHEBI_50313 .
obo:WBPhenotype_0000986 a rdfs:Class ;
rdfs:label "epithelial cell physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the epithelial cell to carry out its normal functions or activities, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000608 .
obo:WBPhenotype_0002542 a rdfs:Class ;
rdfs:label "intranuclear chromatin localization variant"@en ;
rdfs:comment "Cells exhibit specific regions of chromatin (e.g. an integrated array reporter) that localize to different regions within the nucleus, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001348 .
obo:GO_0010165 a rdfs:Class ;
rdfs:label "response to X-ray" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)." ;
rdfs:subClassOf obo:GO_0010212 .
obo:GO_0050849 a rdfs:Class ;
rdfs:label "negative regulation of calcium-mediated signaling" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling." ;
rdfs:subClassOf obo:GO_0050848 , obo:GO_0065007 , obo:GO_1902532 .
obo:GO_0010332 a rdfs:Class ;
rdfs:label "response to gamma radiation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum." ;
rdfs:subClassOf obo:GO_0010212 .
obo:WBPhenotype_0001867 a rdfs:Class ;
rdfs:label "mitotic spindle asters defective early emb" ;
rdfs:comment "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a mitotic cell cycle." ;
rdfs:subClassOf obo:WBPhenotype_0001102 , obo:WBPhenotype_0001110 .
obo:GO_0016482 a rdfs:Class ;
rdfs:label "cytosolic transport" ;
rdfs:comment "The directed movement of substances or organelles within the cytosol." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0046907 .
obo:WBPhenotype_0002283 a rdfs:Class ;
rdfs:label "autophagy reduced" ;
rdfs:comment "Animals exhibit reduced levels of the process by which their cells digest parts of their own cytoplasm, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000736 .
obo:GO_0043231 a rdfs:Class ;
rdfs:label "intracellular membrane-bounded organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0043227 , obo:GO_0043229 .
obo:WBPhenotype_0002655 a rdfs:Class ;
rdfs:label "exopher production in muscle decreased"@en ;
rdfs:comment "Muscle cells exhibit a decrease in production of exophers compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002653 , obo:WBPhenotype_0002654 .
obo:CHEBI_30879 a rdfs:Class ;
rdfs:label "alcohol" ;
rdfs:comment "A compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom." ;
rdfs:subClassOf obo:CHEBI_33822 .
obo:CHEBI_17134 a rdfs:Class ;
rdfs:label "octopamine" ;
rdfs:comment "A member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates." ;
rdfs:subClassOf obo:CHEBI_25990 , obo:CHEBI_27175 .
obo:CHEBI_5118 a rdfs:Class ;
rdfs:label "fluoxetine" ;
rdfs:comment "A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_60911 .
obo:WBPhenotype_0001595 a rdfs:Class ;
rdfs:label "somatic transgene silencing variant" ;
rdfs:comment "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the soma, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001593 .
obo:WBPhenotype_0000121 a rdfs:Class ;
rdfs:label "translation variant" ;
rdfs:comment "Variations in the chemical reactions and pathways resulting in the formation of a protein, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000112 , obo:WBPhenotype_0001644 .
obo:WBPhenotype_0000370 a rdfs:Class ;
rdfs:label "egg long" ;
rdfs:comment "The fertilized oocytes have a greater than standard length measured end to end compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000373 .
obo:WBPhenotype_0001606 a rdfs:Class ;
rdfs:label "ethanol hypersensitive" ;
rdfs:comment "Animals respond to ethanol at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000008 , obo:WBPhenotype_0001918 .
obo:CHEBI_33579 a rdfs:Class ;
rdfs:label "main group molecular entity" ;
rdfs:comment "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:WBbt_0004489 a rdfs:Class ;
rdfs:label "M cell" ;
rdfs:comment "Postembryonic mesoblast of pedigree MSapaapp." ;
rdfs:subClassOf obo:WBbt_0006783 .
obo:WBPhenotype_0001930 a rdfs:Class ;
rdfs:label "muscle arm development defective" ;
rdfs:comment "Animals extend altered or fewer numbers of dorsal and or ventral muscle arms compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000540 .
obo:BFO_0000003 a rdfs:Class ;
rdfs:label "occurrent"@en ;
rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
rdfs:subClassOf obo:BFO_0000001 .
obo:CHEBI_33250 a rdfs:Class ;
rdfs:label "atom" ;
rdfs:comment "A chemical entity constituting the smallest component of an element having the chemical properties of the element." ;
rdfs:subClassOf obo:CHEBI_24431 .
obo:WBPhenotype_0001174 a rdfs:Class ;
rdfs:label "chromosome disjunction defective" ;
rdfs:comment "Chromosomes fail to segregate away from their homolog, resulting in gametes with no or extra copies of the chromosome." ;
rdfs:subClassOf obo:WBPhenotype_0001499 , obo:WBPhenotype_0001882 , obo:WBPhenotype_0002012 .
obo:CHEBI_41609 a rdfs:Class ;
rdfs:label "carbonate" ;
rdfs:subClassOf obo:CHEBI_35604 .
obo:WBPhenotype_0001134 a rdfs:Class ;
rdfs:label "Aba ABp division axis defective early emb" ;
rdfs:comment "ABa or ABp divide in the wrong orientation." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0001133 .
obo:CHEBI_30089 a rdfs:Class ;
rdfs:label "acetate" ;
rdfs:comment "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35757 .
obo:WBPhenotype_0000712 a rdfs:Class ;
rdfs:label "germ cell ionizing radiation response variant" ;
rdfs:comment "Germ cells exhibit variations in their response to ionizing radiation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000987 , obo:WBPhenotype_0001324 .
obo:GO_1902808 a rdfs:Class ;
rdfs:label "positive regulation of cell cycle G1/S phase transition" ;
rdfs:comment "Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901989 , obo:GO_1902806 .
obo:WBPhenotype_0001982 a rdfs:Class ;
rdfs:label "cell membrane organization biogenesis variant" ;
rdfs:comment "Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0010002 .
obo:PATO_0001475 a rdfs:Class ;
rdfs:label "increased position" ;
rdfs:comment "A position which is relatively high." ;
rdfs:subClassOf obo:PATO_0000140 , obo:PATO_0002305 .
obo:WBPhenotype_0000577 a rdfs:Class ;
rdfs:label "organism homeostasis metabolism variant" ;
rdfs:comment "Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000576 .
obo:GO_0042713 a rdfs:Class ;
rdfs:label "sperm ejaculation" ;
rdfs:comment "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract." ;
rdfs:subClassOf obo:GO_0048609 .
obo:CHEBI_33709 a rdfs:Class ;
rdfs:label "amino acid" ;
rdfs:comment "A carboxylic acid containing one or more amino groups." ;
rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_50047 .
obo:WBPhenotype_0000358 a rdfs:Class ;
rdfs:label "extra cell division postembryonic" ;
rdfs:comment "Animals execute supernumerary cell divisions post-hatching." ;
rdfs:subClassOf obo:WBPhenotype_0000825 .
obo:WBPhenotype_0000750 a rdfs:Class ;
rdfs:label "larval development variant" ;
rdfs:comment "Variations in the progression of a larva over time, from its formation to the mature structure compared to control. The larva is the early, immature form of an animal between hatching and adulthood." ;
rdfs:subClassOf obo:WBPhenotype_0000049 .
obo:CHEBI_33290 a rdfs:Class ;
rdfs:label "food" ;
rdfs:comment "A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life." ;
rdfs:subClassOf obo:CHEBI_52211 .
obo:GO_0005740 a rdfs:Class ;
rdfs:label "mitochondrial envelope" ;
rdfs:comment "The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space." ;
rdfs:subClassOf obo:GO_0031967 .
obo:WBPhenotype_0002298 a rdfs:Class ;
rdfs:label "coiling frequency variant" ;
rdfs:comment "Animals exhibit variations in the amount of time spent with its body posture in a coil or the frequency with which they form coils compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002297 .
obo:PATO_0000694 a rdfs:Class ;
rdfs:label "premature" ;
rdfs:comment "A quality of a process which starts earlier than the natural start time or the reference process." ;
rdfs:subClassOf obo:PATO_0002325 .
obo:CHEBI_18248 a rdfs:Class ;
rdfs:label "iron atom" ;
rdfs:comment "An iron group element atom that has atomic number 26." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33356 .
obo:WBPhenotype_0002017 a rdfs:Class ;
rdfs:label "VPC competence variant" ;
rdfs:comment "Any variation in the ability of multipotent vulval precursor cells to respond to signals compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000216 .
obo:GO_0031346 a rdfs:Class ;
rdfs:label "positive regulation of cell projection organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ;
rdfs:subClassOf obo:GO_0031344 , obo:GO_0051130 , obo:GO_0065007 .
obo:WBPhenotype_0000053 a rdfs:Class ;
rdfs:label "paralyzed arrested elongation two fold" ;
rdfs:comment "Movement and elongation ceases at the two-fold stage. The myofilament lattice in body wall muscle cells is variant. However, development in embryos continues. Embryos hatch as inviable larvae." ;
rdfs:subClassOf obo:WBPhenotype_0000050 , obo:WBPhenotype_0000494 .
obo:GO_2001233 a rdfs:Class ;
rdfs:label "regulation of apoptotic signaling pathway" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0042981 , obo:GO_0065007 .
obo:WBPhenotype_0001467 a rdfs:Class ;
rdfs:label "AWC odorant chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWC sensory neuron in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000265 .
obo:WBPhenotype_0000561 a rdfs:Class ;
rdfs:label "head levamisole resistant" ;
rdfs:comment "The heads of animals fail to respond to the concentration of levamisole that elicits a response in control animals. In C. elegans, heads contract at >10uM for intact animals and >1uM for cut animals." ;
rdfs:subClassOf obo:WBPhenotype_0000421 .
obo:GO_0007076 a rdfs:Class ;
rdfs:label "mitotic chromosome condensation" ;
rdfs:comment "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." ;
rdfs:subClassOf obo:GO_0030261 , obo:GO_1903047 .
obo:WBPhenotype_0002615 a rdfs:Class ;
rdfs:label "abnormal accumulation of vacuoles"@en ;
rdfs:comment "Animals accumulate vacuoles in an abnormal manner in cells, tissues, and/or organs of the animal." ;
rdfs:subClassOf obo:WBPhenotype_0000535 .
obo:CHEBI_35473 a rdfs:Class ;
rdfs:label "tranquilizing drug" ;
rdfs:comment "A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour." ;
rdfs:subClassOf obo:CHEBI_35471 , obo:CHEBI_35488 .
obo:CHEBI_50994 a rdfs:Class ;
rdfs:label "primary amino compound" ;
rdfs:comment "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:WBPhenotype_0000527 a rdfs:Class ;
rdfs:label "organism pigmentation phenotype" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism." ;
rdfs:subClassOf obo:WBPhenotype_0000521 .
obo:WBPhenotype_0002189 a rdfs:Class ;
rdfs:label "extra linker cells" ;
rdfs:comment "Animals produce an excess number of linker cells compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001675 , obo:WBPhenotype_0002175 .
obo:CHEBI_49110 a rdfs:Class ;
rdfs:label "peripheral nervous system drug" ;
rdfs:comment "A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:WBPhenotype_0000852 a rdfs:Class ;
rdfs:label "coelomocyte development variant" ;
rdfs:comment "Variations in the progression of a free-floating spherical cell lying in the pseudocoelomic cavity of animals that can endocytose many compounds, possibly for immune surveillance, over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000618 .
obo:WBls_0000108 a rdfs:Class ;
rdfs:label "L3 larval stage" ;
rdfs:comment "The third stage larva of nematodes." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000105 .
obo:CHEBI_58104 a rdfs:Class ;
rdfs:label "nucleoside 5'-triphoshate(3-)" ;
rdfs:comment "Trianion of nucleoside triphosphate arising from deprotonation of three of the four free triphosphate OH groups." ;
rdfs:subClassOf obo:CHEBI_59724 .
obo:WBbt_0005743 a rdfs:Class ;
rdfs:label "digestive tract" ;
rdfs:comment "inner tube of two concentric tubes that make up the body" ;
rdfs:subClassOf obo:WBbt_0005738 .
obo:WBPhenotype_0000206 a rdfs:Class ;
rdfs:label "autosomal nondisjunction meiosis" ;
rdfs:comment "A non-sex chromosome fails to segregate away from its homologous chromosome, resulting in gametes with no or extra copies of the non-sex homolog." ;
rdfs:subClassOf obo:WBPhenotype_0001174 .
obo:GO_0018996 a rdfs:Class ;
rdfs:label "molting cycle, collagen and cuticulin-based cuticle" ;
rdfs:comment "The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans." ;
rdfs:subClassOf obo:GO_0042303 .
obo:WBPhenotype_0001759 a rdfs:Class ;
rdfs:label "21U RNA expression variant" ;
rdfs:comment "Variations in the biogenesis or stability of the 21U-RNA class of molecules compared to control. Molecules are classified as 21U-RNA based on the presence of a 5'U and a conserved upstream motif, which may specify the production of these molecules, in addition these molecules are typically 21nt in length." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:GO_0099577 a rdfs:Class ;
rdfs:label "regulation of translation at presynapse, modulating synaptic transmission" ;
rdfs:comment "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0099171 , obo:GO_0099547 , obo:GO_0140244 .
obo:WBPhenotype_0000390 a rdfs:Class ;
rdfs:label "spermatid activation defective" ;
rdfs:comment "Spermatids fail to mature into active sperm. In C. elegans round sessile spermatids mature into spermatozoa (polarized cells with a motile pseudopod), upon copulation or treatment with proteases." ;
rdfs:subClassOf obo:WBPhenotype_0000670 .
obo:WBPhenotype_0002004 a rdfs:Class ;
rdfs:label "actomyosin contractility defective" ;
rdfs:comment "Animals exhibit defects in the flow rate or targeting of the cortical actomyosin network, which occurs during polarization as well as contraction of the contractile ring, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000034 , obo:WBPhenotype_0001587 , obo:WBPhenotype_0002408 .
obo:GO_0051055 a rdfs:Class ;
rdfs:label "negative regulation of lipid biosynthetic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0045833 , obo:GO_0046890 , obo:GO_0065007 .
obo:GO_2000383 a rdfs:Class ;
rdfs:label "regulation of ectoderm development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of ectoderm development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:WBbt_0008189 a rdfs:Class ;
rdfs:label "seminal vesical cell" ;
rdfs:comment "seminal vesicle cell of male gonad." ;
rdfs:subClassOf obo:WBbt_0008209 .
obo:WBPhenotype_0000168 a rdfs:Class ;
rdfs:label "alae secretion variant" ;
rdfs:comment "Variations in the regulated release of proteins needed for alae formation by epidermal seam cells compared to control. Alae are small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (WormAtlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000258 , obo:WBPhenotype_0000608 , obo:WBPhenotype_0001210 .
obo:GO_0007134 a rdfs:Class ;
rdfs:label "meiotic telophase I" ;
rdfs:comment "The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." ;
rdfs:subClassOf obo:GO_0051326 , obo:GO_0098764 .
obo:GO_0007018 a rdfs:Class ;
rdfs:label "microtubule-based movement" ;
rdfs:comment "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." ;
rdfs:subClassOf obo:GO_0007017 .
obo:CHEBI_76797 a rdfs:Class ;
rdfs:label "EC 2.5.1.18 (glutathione transferase) inhibitor" ;
rdfs:comment "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18)." ;
rdfs:subClassOf obo:CHEBI_76663 .
obo:UBERON_0001016 a rdfs:Class .
obo:WBPhenotype_0001502 a rdfs:Class ;
rdfs:label "chemical resistant" ;
rdfs:comment "Animals fail to respond to the concentration of a specific chemical that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:CHEBI_37749 a rdfs:Class ;
rdfs:label "halogen oxide" ;
rdfs:subClassOf obo:CHEBI_24471 , obo:CHEBI_24836 .
obo:GO_0051673 a rdfs:Class ;
rdfs:label "disruption of plasma membrane integrity in another organism" ;
rdfs:comment "The disruption of the cell membrane of another organism, leading to damage or temporary subversion of the membrane." ;
rdfs:subClassOf obo:GO_0140975 .
obo:WBPhenotype_0001718 a rdfs:Class ;
rdfs:label "instantaneous velocity variant" ;
rdfs:comment "Animals exhibit variations in the mean translocation of the points along the animal's track compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0004025 .
obo:WBPhenotype_0002361 a rdfs:Class ;
rdfs:label "membrane fluidity increased" ;
rdfs:comment "Animals exhibit increased fluidity of cell membranes, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002484 .
obo:WBPhenotype_0002478 a rdfs:Class ;
rdfs:label "axotomy response variant" ;
rdfs:comment "Any variation in the cellular and molecular pathways in a neuron in response to having its axon severed compared to severing in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002563 .
obo:GO_1903504 a rdfs:Class ;
rdfs:label "regulation of mitotic spindle checkpoint" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0065007 , obo:GO_0090231 .
obo:WBPhenotype_0000471 a rdfs:Class ;
rdfs:label "ALM migration variant" ;
rdfs:comment "Any variation in the normal posterior movement of the ALM mechanosensory neurons from their birthplace (anterior to the V1 hypodermal cell) to positions in between the V2 and V3 cells in the embryo compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001520 .
obo:GO_0072384 a rdfs:Class ;
rdfs:label "organelle transport along microtubule" ;
rdfs:comment "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." ;
rdfs:subClassOf obo:GO_0010970 , obo:GO_0051656 .
obo:GO_0035915 a rdfs:Class ;
rdfs:label "pore formation in membrane of another organism" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism." ;
rdfs:subClassOf obo:GO_0051673 .
obo:GO_0019953 a rdfs:Class ;
rdfs:label "sexual reproduction" ;
rdfs:comment "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." ;
rdfs:subClassOf obo:GO_0022414 .
obo:CHEBI_48854 a rdfs:Class ;
rdfs:label "sulfurous acid" ;
rdfs:subClassOf obo:CHEBI_33402 .
obo:CHEBI_51323 a rdfs:Class ;
rdfs:label "cinchona alkaloid" ;
rdfs:comment "An alkaloid based on a cinchonan skeleton." ;
rdfs:subClassOf obo:CHEBI_26509 .
obo:GO_0005737 a rdfs:Class ;
rdfs:label "cytoplasm" ;
rdfs:comment "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0007027 a rdfs:Class ;
rdfs:label "negative regulation of axonemal microtubule depolymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." ;
rdfs:subClassOf obo:GO_0007026 , obo:GO_0010937 , obo:GO_0031345 , obo:GO_0065007 , obo:GO_0120035 .
obo:WBbt_0004112 a rdfs:Class ;
rdfs:label "PHso1L" ;
rdfs:comment "Post-embryonic cell of pedigree TL.paa, phasmid sockets." ;
rdfs:subClassOf obo:WBbt_0007030 , obo:WBbt_0008410 .
obo:CHEBI_52090 a rdfs:Class ;
rdfs:label "methoxide" ;
rdfs:comment "An organic anion that is the conjugate base of methanol." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25696 .
obo:WBPhenotype_0001552 a rdfs:Class ;
rdfs:label "dauer pharynx morphology variant" ;
rdfs:comment "Variations in the form or composition of the mouthparts at the anterior end of the digestive tract during the dauer stage, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000709 , obo:WBPhenotype_0001545 .
obo:CHEBI_17590 a rdfs:Class ;
rdfs:label "octane" ;
rdfs:comment "A straight chain alkane composed of 8 carbon atoms." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_18310 .
obo:WBPhenotype_0002171 a rdfs:Class ;
rdfs:label "alkaline pH chemotaxis variant" ;
rdfs:comment "Animals exhibit variations in the characteristic movement towards typically attractive alkaline pH (pH higher than 7) compared to control. However animals tend to avoid very high pH levels (pH11). pH is a measure of the acidity or basicity of an aqueous solution. In C. elegans animals chemotax toward higher alkaline pH." ;
rdfs:subClassOf obo:WBPhenotype_0001047 .
obo:GO_0001956 a rdfs:Class ;
rdfs:label "positive regulation of neurotransmitter secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." ;
rdfs:subClassOf obo:GO_0046928 , obo:GO_0050806 , obo:GO_0051590 , obo:GO_0065007 , obo:GO_1903532 .
obo:WBPhenotype_0002023 a rdfs:Class ;
rdfs:label "spike frequency variant" ;
rdfs:comment "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed either at the cell body or the synaptic region, which are independent of presynaptic inputs." ;
rdfs:subClassOf obo:WBPhenotype_0002020 .
obo:WBbt_0005448 a rdfs:Class ;
rdfs:label "preanal ganglion" ;
rdfs:comment "ganglion anterior to the anus." ;
rdfs:subClassOf obo:WBbt_0005332 .
obo:WBbt_0006941 a rdfs:Class ;
rdfs:label "ray" ;
rdfs:comment "male sensory organ; nine bilateral pairs of finger-like rays (numbered 1 to 9, Left/Right) radiate from the tail and are embedded in a cuticlar fan." ;
rdfs:subClassOf obo:WBbt_0005757 , obo:WBbt_0006929 .
obo:CHEBI_24852 a rdfs:Class ;
rdfs:label "insecticide" ;
rdfs:comment "Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects." ;
rdfs:subClassOf obo:CHEBI_25944 .
obo:WBPhenotype_0001812 a rdfs:Class ;
rdfs:label "embryonic rupture" ;
rdfs:comment "During development of the embryo, the epidermis loses integrity and the contents of the embryo are expelled." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:CHEBI_77703 a rdfs:Class ;
rdfs:label "EC 4.3.1.3 (histidine ammonia-lyase) inhibitor" ;
rdfs:comment "An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3)." ;
rdfs:subClassOf obo:CHEBI_76832 .
obo:WBPhenotype_0000590 a rdfs:Class ;
rdfs:label "cell corpse number variant" ;
rdfs:comment "Animals exhibit differences in the number of cell corpses compared to controls at the same developmental life stage." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:WBPhenotype_0001359 a rdfs:Class ;
rdfs:label "proctodeum morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure and organization of the chamber in the male tail that extends from the termination of four canals (vas deferens, gut, and left and right spicule channels) to just before the cloaca, from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000070 , obo:WBPhenotype_0000910 .
obo:WBPhenotype_0000217 a rdfs:Class ;
rdfs:label "prolonged pharyngeal contraction" ;
rdfs:comment "The time in which a muscle contraction event that controls feeding is increased compared to control. Contractions of the pharynx are necessary for bacterial uptake from the surrounding environment." ;
rdfs:subClassOf obo:WBPhenotype_0000980 .
obo:CHEBI_35820 a rdfs:Class ;
rdfs:label "antiprotozoal drug" ;
rdfs:comment "Any antimicrobial drug which is used to treat or prevent protozoal infections." ;
rdfs:subClassOf obo:CHEBI_35442 , obo:CHEBI_36043 .
obo:PATO_0002007 a rdfs:Class ;
rdfs:label "convex 3-D shape" ;
rdfs:comment "A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave." ;
rdfs:subClassOf obo:PATO_0002266 .
obo:RO_0015011 a rdf:Property ;
rdfs:range .
obo:CHEBI_35741 a rdfs:Class ;
rdfs:label "glycerolipid" ;
rdfs:comment "Any member of the group of lipids containing a common glycerol backbone to which at least one fatty acid-derived group is attached." ;
rdfs:subClassOf obo:CHEBI_18059 .
obo:GO_0070161 a rdfs:Class ;
rdfs:label "anchoring junction" ;
rdfs:comment "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." ;
rdfs:subClassOf obo:GO_0030054 .
obo:WBPhenotype_0002069 a rdfs:Class ;
rdfs:label "axon termination defective" ;
rdfs:comment "Axons in animals do not end in the same manner as they do in control animals. Some defects described include an overextension of the axon or termination of the axon in the shape of a hook, either large or small." ;
rdfs:subClassOf obo:WBPhenotype_0000180 .
obo:WBPhenotype_0000127 a rdfs:Class ;
rdfs:label "dauer recovery variant" ;
rdfs:comment "Characteristic exit from the dauer stage is altered compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000308 .
obo:WBPhenotype_0000550 a rdfs:Class ;
rdfs:label "body muscle dystrophy" ;
rdfs:comment "Progressive degeneration of muscle along the body wall." ;
rdfs:subClassOf obo:WBPhenotype_0000548 , obo:WBPhenotype_0000596 .
obo:GO_1902275 a rdfs:Class ;
rdfs:label "regulation of chromatin organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of chromatin organization." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:WBPhenotype_0000431 a rdfs:Class ;
rdfs:label "hermaphrodite copulatory structure development variant" ;
rdfs:comment "Any variation in the progression of the specialized structures of a hermaphrodite which allow the successful transfer of sperm from a male, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000429 .
obo:CHEBI_52209 a rdfs:Class ;
rdfs:label "aetiopathogenetic role" ;
rdfs:comment "A role played by the molecular entity or part thereof which causes the development of a pathological process." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:WBPhenotype_0001252 a rdfs:Class ;
rdfs:label "wing cilia axoneme morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of the microtubule-based fibrillar section, axoneme, of the cilia of the flat sheet-like cells associated with sensory function, from that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001248 .
obo:WBPhenotype_0001066 a rdfs:Class ;
rdfs:label "inactive phase variant" ;
rdfs:comment "The period during which the animal is less likely to lay eggs is not typical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ;
rdfs:subClassOf obo:WBPhenotype_0001063 .
obo:GO_0001704 a rdfs:Class ;
rdfs:label "formation of primary germ layer" ;
rdfs:comment "The formation of the ectoderm, mesoderm and endoderm during gastrulation." ;
rdfs:subClassOf obo:GO_0048646 .
obo:WBPhenotype_0002131 a rdfs:Class ;
rdfs:label "muscle cell ultrastructure variant" ;
rdfs:comment "Animals display variations in the structure or organization of the components of the muscle, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000904 .
obo:WBPhenotype_0002423 a rdfs:Class ;
rdfs:label "hypoxia response variant" ;
rdfs:comment "Animals exhibit variations in response to hypoxia, low oxygen conditions, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000067 , obo:WBPhenotype_0000464 .
obo:WBPhenotype_0002392 a rdfs:Class ;
rdfs:label "age dependent somatic depletion of fat" ;
rdfs:comment "A depletion of somatic, but not germline, lipid stores are observed near the end of the reproductive period." ;
rdfs:subClassOf obo:WBPhenotype_0001183 .
obo:GO_0010496 a rdfs:Class ;
rdfs:label "intercellular transport" ;
rdfs:comment "The movement of substances between cells." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 .
obo:WBPhenotype_0002553 a rdfs:Class ;
rdfs:label "organ phenotype"@en ;
rdfs:comment "A phenotype affecting a particular organ." ;
rdfs:subClassOf obo:WBPhenotype_0002551 .
obo:WBPhenotype_0002495 a rdfs:Class ;
rdfs:label "ectopic hypodermis"@en ;
rdfs:comment "Animals exhibit one or more hypodermal cells in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0002493 , obo:WBPhenotype_0002556 .
obo:GO_0006935 a rdfs:Class ;
rdfs:label "chemotaxis" ;
rdfs:comment "The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ;
rdfs:subClassOf obo:GO_0042330 .
obo:WBPhenotype_0002063 a rdfs:Class ;
rdfs:label "maintenance of gene silencing variant" ;
rdfs:comment "Animals differ from controls in the expression of genes targeted for silencing (gene inactivation) in subsequent generations via transcriptional or post-transcriptional processes." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:GO_0002376 a rdfs:Class ;
rdfs:label "immune system process" ;
rdfs:comment "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CHEBI_149553 a rdfs:Class ;
rdfs:label "anticoronaviral agent" ;
rdfs:comment "Any antiviral agent which inhibits the activity of coronaviruses." ;
rdfs:subClassOf obo:CHEBI_22587 .
obo:GO_0042338 a rdfs:Class ;
rdfs:label "cuticle development involved in collagen and cuticulin-based cuticle molting cycle" ;
rdfs:comment "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans." ;
rdfs:subClassOf obo:GO_0040002 , obo:GO_0042335 .
obo:GO_0007399 a rdfs:Class ;
rdfs:label "nervous system development" ;
rdfs:comment "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." ;
rdfs:subClassOf obo:GO_0048731 .
obo:WBPhenotype_0000239 a rdfs:Class ;
rdfs:label "vulval cell lineage variant" ;
rdfs:comment "The descendants of a vulval precursor cell exhibit altered developmental programs compared to their counterparts in control animals. In C. elegans, the VPCs are P3.p-P8.p." ;
rdfs:subClassOf obo:WBPhenotype_0000099 .
obo:CHEBI_33702 a rdfs:Class ;
rdfs:label "polyatomic cation" ;
rdfs:comment "A cation consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_36358 , obo:CHEBI_36916 .
obo:CHEBI_59517 a rdfs:Class ;
rdfs:label "DNA synthesis inhibitor" ;
rdfs:comment "Any substance that inhibits the synthesis of DNA." ;
rdfs:subClassOf obo:CHEBI_76932 .
obo:WBPhenotype_0004003 a rdfs:Class ;
rdfs:label "mate finding defective" ;
rdfs:comment "Males exhibit defects in their response to the mate-finding cue." ;
rdfs:subClassOf obo:WBPhenotype_0004005 .
obo:GO_0051325 a rdfs:Class ;
rdfs:label "interphase" ;
rdfs:comment "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs." ;
rdfs:subClassOf obo:GO_0022403 .
obo:PATO_0002247 a rdfs:Class ;
rdfs:label "degree of pigmentation" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's having or lacking of substances produced by living organisms that have a color resulting from selective color absorption." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:RO_0002610 a rdf:Property ;
rdfs:range .
obo:WBPhenotype_0002563 a rdfs:Class ;
rdfs:label "neuron physiology phenotype"@en ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the neuron to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000612 .
obo:GO_0099537 a rdfs:Class ;
rdfs:label "trans-synaptic signaling" ;
rdfs:comment "Cell-cell signaling in either direction across the synaptic cleft." ;
rdfs:subClassOf obo:GO_0099536 .
obo:WBPhenotype_0002604 a rdfs:Class ;
rdfs:label "dipeptide repeat protein toxicity abnormal"@en ;
rdfs:comment "Animals exhibit an abnormal response to toxic dipeptide repeat proteins, either via exposure in the environment or expressed within the organism, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002603 .
obo:WBPhenotype_0001852 a rdfs:Class ;
rdfs:label "antihelmintic response variant" ;
rdfs:comment "Animals exhibit variations in their response to an agent that destroys or causes the expulsion of parasitic intestinal worms compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000459 .
obo:GO_0030858 a rdfs:Class ;
rdfs:label "positive regulation of epithelial cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." ;
rdfs:subClassOf obo:GO_0030856 , obo:GO_0045597 , obo:GO_0065007 .
obo:CHEBI_36820 a rdfs:Class ;
rdfs:label "ring assembly" ;
rdfs:comment "Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:WBPhenotype_0001539 a rdfs:Class ;
rdfs:label "dauer induction variant" ;
rdfs:comment "Animals exhibit variations in the entry into the dauer stage when exposed to conditions that induce dauer formation in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000308 .
obo:GO_0061061 a rdfs:Class ;
rdfs:label "muscle structure development" ;
rdfs:comment "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." ;
rdfs:subClassOf obo:GO_0048856 .
obo:WBPhenotype_0002118 a rdfs:Class ;
rdfs:label "population fitness phenotype" ;
rdfs:comment "Populations exhibit variations in the ability to survive, grow and reproduce, thus affecting the contribution to the gene pool over generations compared to control populations. In C. elegans the fitness of a population can by assessed by measuring the rate at which E. coli is consumed." ;
rdfs:subClassOf obo:WBPhenotype_0000519 .
obo:WBPhenotype_0002036 a rdfs:Class ;
rdfs:label "susceptible to lectin" ;
rdfs:comment "Exposure to lectin results in altered behavior, growth, or development of the animal compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002031 .
obo:WBPhenotype_0000064 a rdfs:Class ;
rdfs:label "sexually dimorphic lethality" ;
rdfs:comment "Animals die prematurely at any stage of the life cycle in a sex dependent manner." ;
rdfs:subClassOf obo:WBPhenotype_0000062 .
obo:WBPhenotype_0002412 a rdfs:Class ;
rdfs:label "cleavage furrow termination defective" ;
rdfs:comment "Cells exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ;
rdfs:subClassOf obo:WBPhenotype_0002410 .
obo:PATO_0001780 a rdfs:Class ;
rdfs:label "dystrophic" ;
rdfs:comment "A size quality inhering in a bearer by virtue of the bearer's being abnormally developed, usually due to malnutrition." ;
rdfs:subClassOf obo:PATO_0000587 .
obo:WBPhenotype_0001382 a rdfs:Class ;
rdfs:label "protein modification variant" ;
rdfs:comment "Variations in the covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications), compared to control. This includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." ;
rdfs:subClassOf obo:WBPhenotype_0000112 , obo:WBPhenotype_0001644 .
obo:GO_0033316 a rdfs:Class ;
rdfs:label "meiotic spindle assembly checkpoint signaling" ;
rdfs:comment "A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle." ;
rdfs:subClassOf obo:GO_0044779 , obo:GO_0071173 .
obo:WBPhenotype_0000183 a rdfs:Class ;
rdfs:label "apoptosis increased" ;
rdfs:comment "Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000730 , obo:WBPhenotype_0002619 .
obo:GO_1902413 a rdfs:Class ;
rdfs:label "negative regulation of mitotic cytokinesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis." ;
rdfs:subClassOf obo:GO_0032466 , obo:GO_0065007 , obo:GO_1902412 .
obo:CHEBI_23004 a rdfs:Class ;
rdfs:label "carbamoyl group" ;
rdfs:comment "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." ;
rdfs:subClassOf obo:CHEBI_27207 .
obo:CHEBI_76760 a rdfs:Class ;
rdfs:label "EC 3.1.* (ester hydrolase) inhibitor" ;
rdfs:comment "A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*)." ;
rdfs:subClassOf obo:CHEBI_76759 .
obo:CHEBI_33340 a rdfs:Class ;
rdfs:label "zinc group element atom" ;
rdfs:subClassOf obo:CHEBI_33561 .
obo:WBPhenotype_0001643 a rdfs:Class ;
rdfs:label "excess hypodermal cells" ;
rdfs:comment "Embryos generate an excess number of hypodermal cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002175 , obo:WBPhenotype_0002569 .
obo:WBPhenotype_0002228 a rdfs:Class ;
rdfs:label "aluminum response variant" ;
rdfs:comment "Animals exhibit variations in their response to aluminum compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 , obo:WBPhenotype_0000591 .
obo:WBbt_0008629 a rdfs:Class ;
rdfs:label "gonad arm" ;
rdfs:comment "A lobe of the gonad. In a monodelphic gonad, there is one arm, whereas in a didelphic gonad, there are two arms." ;
rdfs:subClassOf obo:WBbt_0005729 .
obo:GO_0030588 a rdfs:Class ;
rdfs:label "pseudocleavage" ;
rdfs:comment "Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_1900243 a rdfs:Class ;
rdfs:label "negative regulation of synaptic vesicle endocytosis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis." ;
rdfs:subClassOf obo:GO_0045806 , obo:GO_0065007 , obo:GO_1900242 , obo:GO_1903422 .
obo:WBPhenotype_0000700 a rdfs:Class ;
rdfs:label "multivulva" ;
rdfs:comment "Multiple vulva-like protrusions are present along the ventral side of the animal. In C. elegans, this is usually a result of all six vulval precursor cells adopting primary or secondary vulval fates." ;
rdfs:subClassOf obo:WBPhenotype_0000218 , obo:WBPhenotype_0002553 .
obo:GO_0071214 a rdfs:Class ;
rdfs:label "cellular response to abiotic stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus." ;
rdfs:subClassOf obo:GO_0009628 , obo:GO_0104004 .
obo:GO_1901032 a rdfs:Class ;
rdfs:label "negative regulation of response to reactive oxygen species" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901031 , obo:GO_1902883 .
obo:WBPhenotype_0002060 a rdfs:Class ;
rdfs:label "pore forming toxin resistant" ;
rdfs:comment "Animals fail to respond to the concentration of pore forming toxins that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0002058 .
obo:GO_1902680 a rdfs:Class ;
rdfs:label "positive regulation of RNA biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010557 , obo:GO_0051254 , obo:GO_0065007 , obo:GO_2001141 .
obo:WBPhenotype_0002623 a rdfs:Class ;
rdfs:label "no induction of antimicrobial peptide expression after injury"@en ;
rdfs:comment "Animals exhibit no induction of expression of an antimicrobial peptide after an injury, unlike control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001840 , obo:WBPhenotype_0002621 .
obo:CHEBI_48578 a rdfs:Class ;
rdfs:label "radical scavenger" ;
rdfs:comment "A role played by a substance that can react readily with, and thereby eliminate, radicals." ;
rdfs:subClassOf obo:CHEBI_22586 .
obo:GO_0050795 a rdfs:Class ;
rdfs:label "regulation of behavior" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 .
obo:GO_0010647 a rdfs:Class ;
rdfs:label "positive regulation of cell communication" ;
rdfs:comment "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0048522 , obo:GO_0065007 .
obo:WBPhenotype_0001412 a rdfs:Class ;
rdfs:label "alae morphology variant" ;
rdfs:comment "Animals exhibit variations in the organization of the longitudinal ridges on the cuticle along the length of the animal, from that observed for control animals of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0000948 .
obo:WBPhenotype_0001815 a rdfs:Class ;
rdfs:label "desynapsis defective" ;
rdfs:comment "Animals exhibit defects in the asymmetric diassembly of the synaptonemal complex during progression through meiosis." ;
rdfs:subClassOf obo:WBPhenotype_0002012 .
obo:GO_0140657 a rdfs:Class ;
rdfs:label "ATP-dependent activity" ;
rdfs:comment "A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient." ;
rdfs:subClassOf obo:GO_0003674 .
obo:WBbt_0008424 a rdfs:Class ;
rdfs:label "gubernaculum" ;
rdfs:comment "A sclerotized cuticular structure at the base of the male tail fan which houses the retracted spicules and guides the eversion of the spicules through the anus." ;
rdfs:subClassOf obo:WBbt_0005766 .
obo:PATO_0001873 a rdfs:Class ;
rdfs:label "cylindrical" ;
rdfs:comment "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section." ;
rdfs:subClassOf obo:PATO_0002007 .
obo:WBPhenotype_0002045 a rdfs:Class ;
rdfs:label "cell corpse number decreased" ;
rdfs:comment "Animals exhibit fewer cell corpses compared to controls at the same developmental life stage." ;
rdfs:subClassOf obo:WBPhenotype_0000590 .
obo:WBbt_0007816 a rdfs:Class ;
rdfs:label "spermathecal cell" ;
rdfs:comment "cell of the hermaphrodite spermatheca." ;
rdfs:subClassOf obo:WBbt_0007815 .
obo:CHEBI_24837 a rdfs:Class ;
rdfs:label "inorganic peroxide" ;
rdfs:comment "Compounds of structure ROOR' in which R and R' are inorganic groups." ;
rdfs:subClassOf obo:CHEBI_24836 , obo:CHEBI_25940 .
obo:WBPhenotype_0001241 a rdfs:Class ;
rdfs:label "obsolete ray fusion" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000046 a rdfs:Class ;
rdfs:label "pace of P lineage defective early emb" ;
rdfs:comment "More than five minutes between AB and P1 divisions." ;
rdfs:subClassOf obo:WBPhenotype_0000746 , obo:WBPhenotype_0000824 .
obo:WBPhenotype_0000306 a rdfs:Class ;
rdfs:label "transgene expression variant" ;
rdfs:comment "Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:GO_0042427 a rdfs:Class ;
rdfs:label "serotonin biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ;
rdfs:subClassOf obo:GO_0042428 , obo:GO_0042435 , obo:GO_0046189 , obo:GO_1901162 .
obo:WBPhenotype_0001625 a rdfs:Class ;
rdfs:label "male tail curling serotonin hypersensitive" ;
rdfs:comment "Males respond to serotonin by curling their tails at a lower concentration or a shorter exposure compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body." ;
rdfs:subClassOf obo:WBPhenotype_0000023 , obo:WBPhenotype_0001623 .
obo:WBPhenotype_0001700 a rdfs:Class ;
rdfs:label "swimming variant" ;
rdfs:comment "Animals exhibit variations in movement in liquid from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001206 .
obo:CHEBI_51869 a rdfs:Class ;
rdfs:label "alpha-diketone" ;
rdfs:comment "A diketone that has its two ketone functionalities on adjacent atoms." ;
rdfs:subClassOf obo:CHEBI_46640 .
obo:WBPhenotype_0001308 a rdfs:Class ;
rdfs:label "weak pumping" ;
rdfs:comment "The contraction and relaxation movements of the pharyngeal muscle that mediate feeding is not as robust as compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000634 .
obo:GO_0010937 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic microtubule depolymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." ;
rdfs:subClassOf obo:GO_0031114 , obo:GO_0065007 .
obo:WBPhenotype_0004014 a rdfs:Class ;
rdfs:label "post male contact variant" ;
rdfs:comment "Any variation in the specific actions or reactions of a hermaphrodite after male contact during mating compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0004001 .
obo:CHEBI_18723 a rdfs:Class ;
rdfs:label "nicotine" ;
rdfs:comment "A racemate composed of equimolar amounts of (R)- and (S)-nicotine." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_60911 .
obo:GO_1905879 a rdfs:Class ;
rdfs:label "regulation of oogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of oogenesis." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0060284 , obo:GO_0065007 , obo:GO_2000241 .
obo:GO_0040017 a rdfs:Class ;
rdfs:label "positive regulation of locomotion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." ;
rdfs:subClassOf obo:GO_0040012 , obo:GO_0048518 , obo:GO_0065007 .
obo:WBPhenotype_0002077 a rdfs:Class ;
rdfs:label "dopamine resistant" ;
rdfs:comment "Animals fail to respond to the concentration of a dopamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 .
obo:GO_0005859 a rdfs:Class ;
rdfs:label "muscle myosin complex" ;
rdfs:comment "A filament of myosin found in a muscle cell of any type." ;
rdfs:subClassOf obo:GO_0016460 .
obo:GO_0046661 a rdfs:Class ;
rdfs:label "male sex differentiation" ;
rdfs:comment "The establishment of the sex of a male organism by physical differentiation." ;
rdfs:subClassOf obo:GO_0007548 .
obo:CHEBI_24913 a rdfs:Class ;
rdfs:label "isoprenoid" ;
rdfs:comment "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives." ;
rdfs:subClassOf obo:CHEBI_18059 .
obo:GO_0051246 a rdfs:Class ;
rdfs:label "regulation of protein metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." ;
rdfs:subClassOf obo:GO_0060255 , obo:GO_0065007 , obo:GO_0080090 .
obo:CHEBI_64766 a rdfs:Class ;
rdfs:label "cationic group" ;
rdfs:comment "A group that carries an overall positive charge." ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:GO_0050709 a rdfs:Class ;
rdfs:label "negative regulation of protein secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." ;
rdfs:subClassOf obo:GO_0050708 , obo:GO_0051224 , obo:GO_0065007 , obo:GO_1903531 .
obo:CHEBI_33942 a rdfs:Class ;
rdfs:label "ribose" ;
rdfs:comment "Any aldopentose where the open-chain form has all the hydroxy groups on the same side in the Fischer projection. Occurrs in two enantiomeric forms, D- and L-ribose, of which only the former is found in nature." ;
rdfs:subClassOf obo:CHEBI_33916 .
obo:WBPhenotype_0001901 a rdfs:Class ;
rdfs:label "fat associated bodies variant" ;
rdfs:comment "Animals exhibit variations in the formation or disassembly of fat containing organelles compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001344 .
obo:GO_0062012 a rdfs:Class ;
rdfs:label "regulation of small molecule metabolic process" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:PATO_0001300 a rdfs:Class ;
rdfs:label "optical quality" ;
rdfs:comment "An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light." ;
rdfs:subClassOf obo:PATO_0070060 .
obo:WBPhenotype_0001640 a rdfs:Class ;
rdfs:label "acidification level defective" ;
rdfs:comment "Animals are unable to acidify compartments to the same level as that observed in control animals given the same stimulus." ;
rdfs:subClassOf obo:WBPhenotype_0000607 .
obo:WBPhenotype_0000291 a rdfs:Class ;
rdfs:label "no oocytes" ;
rdfs:comment "Hermaphrodites lack fully specialized female gametes that are competent for fertilization." ;
rdfs:subClassOf obo:WBPhenotype_0000395 , obo:WBPhenotype_0002552 .
obo:WBPhenotype_0000981 a rdfs:Class ;
rdfs:label "spermatocyte meiosis variant" ;
rdfs:comment "Animals exhibit variations in the meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids (non-motile sperm) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000670 , obo:WBPhenotype_0000987 .
obo:WBPhenotype_0001201 a rdfs:Class ;
rdfs:label "no expulsion defecation" ;
rdfs:comment "Animals lack the stereotyped muscle contractions that result in the opening of anus." ;
rdfs:subClassOf obo:WBPhenotype_0000391 .
obo:PATO_0002052 a rdfs:Class ;
rdfs:label "decreased occurrence" ;
rdfs:comment "An occurrence which is relatively low." ;
rdfs:subClassOf obo:PATO_0000057 , obo:PATO_0002302 .
obo:CHEBI_35276 a rdfs:Class ;
rdfs:label "ammonium compound" ;
rdfs:comment "Compounds (NH4+)Y− and derivatives, in which one or more of the hydrogens bonded to nitrogen have been replaced with univalent groups." ;
rdfs:subClassOf obo:CHEBI_51143 .
obo:WBPhenotype_0001472 a rdfs:Class ;
rdfs:label "isoamyl alcohol chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of isoamyl alcohol. In C. elegans, at specific concentrations, isoamyl alcohol is an attractant." ;
rdfs:subClassOf obo:WBPhenotype_0001467 .
obo:GO_0010563 a rdfs:Class ;
rdfs:label "negative regulation of phosphorus metabolic process" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0051174 , obo:GO_0065007 .
obo:CL_0000007 a rdfs:Class ;
rdfs:label "early embryonic cell (metazoa)" ;
rdfs:comment "A cell found in the embryo before the formation of all the gem layers is complete." ;
rdfs:subClassOf obo:CL_0002321 .
obo:GO_0051782 a rdfs:Class ;
rdfs:label "negative regulation of cell division" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0051302 , obo:GO_0065007 .
obo:CHEBI_47901 a rdfs:Class ;
rdfs:label "alkanesulfonic acid" ;
rdfs:comment "Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an alkyl group." ;
rdfs:subClassOf obo:CHEBI_33551 .
obo:CHEBI_25224 a rdfs:Class ;
rdfs:label "methanesulfonate" ;
rdfs:comment "A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid." ;
rdfs:subClassOf obo:CHEBI_62081 .
obo:WBPhenotype_0002056 a rdfs:Class ;
rdfs:label "eating variant" ;
rdfs:comment "Any variation in the specific actions or reactions of an organism causing an alteration in the ingestion of food compared to control animals. In C. elegans the main food source is bacteria and alterations in eating behavior usually lead to malnutrition." ;
rdfs:subClassOf obo:WBPhenotype_0000659 .
obo:GO_1900180 a rdfs:Class ;
rdfs:label "regulation of protein localization to nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to nucleus." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_0051235 a rdfs:Class ;
rdfs:label "maintenance of location" ;
rdfs:comment "Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0051179 .
obo:WBbt_0008435 a rdfs:Class ;
rdfs:label "uterine epithelial cell" ;
rdfs:comment "cell of the epithelia of uterus." ;
rdfs:subClassOf obo:WBbt_0003672 .
obo:PATO_0001511 a rdfs:Class ;
rdfs:label "non-functional" ;
rdfs:comment "A disfunctional quality held by the bearer when the latter is unable to perform a regular function(s)." ;
rdfs:subClassOf obo:PATO_0001509 .
obo:WBPhenotype_0002261 a rdfs:Class ;
rdfs:label "neurite connectivity defective" ;
rdfs:comment "An effective connection between reciprocal target neurons is not established properly." ;
rdfs:subClassOf obo:WBPhenotype_0000623 .
obo:CHEBI_22160 a rdfs:Class ;
rdfs:label "acetamides" ;
rdfs:comment "Compounds with the general formula RNHC(=O)CH3." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:CHEBI_27732 a rdfs:Class ;
rdfs:label "caffeine" ;
rdfs:comment "A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee." ;
rdfs:subClassOf obo:CHEBI_27134 .
obo:WBPhenotype_0001793 a rdfs:Class ;
rdfs:label "aboc expulsion missing" ;
rdfs:comment "The anterior body contraction and expulsion steps of the defecation cycle are absent; posterior body contractions are still present." ;
rdfs:subClassOf obo:WBPhenotype_0000391 .
obo:PATO_0002051 a rdfs:Class ;
rdfs:label "increased occurrence" ;
rdfs:comment "An occurrence which is relatively high." ;
rdfs:subClassOf obo:PATO_0000057 , obo:PATO_0002304 .
obo:GO_0032970 a rdfs:Class ;
rdfs:label "regulation of actin filament-based process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0000191 a rdfs:Class ;
rdfs:label "organism crowding response variant" ;
rdfs:comment "Animals exhibit variations in their response to a situation when there is too high a density of nematodes to be supported by the available amount of food and space compared to that observed in control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBPhenotype_0000400 a rdfs:Class ;
rdfs:label "somatic gonad primordium development defective" ;
rdfs:comment "The developmental progression of the set of precursor cells that later give rise to the somatic tissues of the gonadal tract is impaired (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000399 .
obo:WBPhenotype_0000769 a rdfs:Class ;
rdfs:label "cytoplasmic appearance defective early emb" ;
rdfs:comment "Embryos exhibit defects in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control embryos." ;
rdfs:subClassOf obo:WBPhenotype_0001100 , obo:WBPhenotype_0001427 .
obo:WBPhenotype_0000353 a rdfs:Class ;
rdfs:label "backing increased" ;
rdfs:comment "Animals spend more time backing compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001005 .
obo:GO_0009059 a rdfs:Class ;
rdfs:label "macromolecule biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0043170 .
obo:WBPhenotype_0002126 a rdfs:Class ;
rdfs:label "intestinal fluorescence decreased" ;
rdfs:comment "Animals exhibit a decrease in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine." ;
rdfs:subClassOf obo:WBPhenotype_0000293 .
obo:GO_0015031 a rdfs:Class ;
rdfs:label "protein transport" ;
rdfs:comment "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0008104 , obo:GO_0045184 .
obo:WBPhenotype_0004025 a rdfs:Class ;
rdfs:label "velocity of movement variant" ;
rdfs:comment "Animals exhibit variations in the net velocity of an animal, that is, the maximum distance an animal traverses over an extended period of time, from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000641 .
obo:WBPhenotype_0001906 a rdfs:Class ;
rdfs:label "hypodermal cell elongation defective" ;
rdfs:comment "During epidermal morphogenesis, hypodermal cells do not properly undergo the characteristic cell shape changes necessary for the embryo to elongate." ;
rdfs:subClassOf obo:WBPhenotype_0002569 .
obo:WBPhenotype_0000165 a rdfs:Class ;
rdfs:label "cell fusion variant" ;
rdfs:comment "Variations in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:CHEBI_59769 a rdfs:Class ;
rdfs:label "acetal" ;
rdfs:comment "An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' ≠ H). Mixed acetals have R'' and R''' groups which differ." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:CHEBI_26348 a rdfs:Class ;
rdfs:label "prosthetic group" ;
rdfs:comment "A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity." ;
rdfs:subClassOf obo:CHEBI_23357 .
obo:GO_0051961 a rdfs:Class ;
rdfs:label "negative regulation of nervous system development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0051960 , obo:GO_0065007 .
obo:GO_1901860 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial DNA metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0010821 , obo:GO_0051054 , obo:GO_0065007 , obo:GO_1901858 .
obo:GO_1903537 a rdfs:Class ;
rdfs:label "meiotic cell cycle process involved in oocyte maturation" ;
rdfs:comment "Any meiotic cell cycle process that is involved in oocyte maturation." ;
rdfs:subClassOf obo:GO_1903046 .
obo:CHEBI_39418 a rdfs:Class ;
rdfs:label "straight-chain saturated fatty acid" ;
rdfs:comment "Any saturated fatty acid lacking a side-chain." ;
rdfs:subClassOf obo:CHEBI_26607 , obo:CHEBI_59202 .
obo:GO_0080171 a rdfs:Class ;
rdfs:label "lytic vacuole organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole." ;
rdfs:subClassOf obo:GO_0007033 .
obo:WBPhenotype_0002007 a rdfs:Class ;
rdfs:label "cortical blebs present" ;
rdfs:comment "Embryos display cortical protusions during cytokinesis." ;
rdfs:subClassOf obo:WBPhenotype_0000764 , obo:WBPhenotype_0002408 .
obo:GO_1905132 a rdfs:Class ;
rdfs:label "regulation of meiotic chromosome separation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of meiotic chromosome separation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905818 , obo:GO_2000241 .
obo:WBPhenotype_0001557 a rdfs:Class ;
rdfs:label "dauer labial sensillum variant" ;
rdfs:comment "Dauer stage animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth." ;
rdfs:subClassOf obo:WBPhenotype_0001531 , obo:WBPhenotype_0001556 .
obo:GO_1905084 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial translational elongation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation." ;
rdfs:subClassOf obo:GO_0045901 , obo:GO_0065007 , obo:GO_1905082 .
obo:CHEBI_52211 a rdfs:Class ;
rdfs:label "physiological role" ;
rdfs:comment "A biological role relating to the normal mechanisms and their interactions within a living system." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_43799 a rdfs:Class ;
rdfs:label "butan-1-amine" ;
rdfs:comment "A primary aliphatic amine that is butane substituted by an amino group at position 1." ;
rdfs:subClassOf obo:CHEBI_17062 .
obo:WBbt_0005746 a rdfs:Class ;
rdfs:label "Organ system" ;
rdfs:comment "intergrated group of organs, performing one or more unified functions." ;
rdfs:subClassOf obo:WBbt_0005763 .
obo:GO_0043085 a rdfs:Class ;
rdfs:label "positive regulation of catalytic activity" ;
rdfs:comment "Any process that activates or increases the activity of an enzyme." ;
rdfs:subClassOf obo:GO_0044093 , obo:GO_0050790 , obo:GO_0065007 .
obo:CHEBI_35366 a rdfs:Class ;
rdfs:label "fatty acid" ;
rdfs:comment "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids." ;
rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_25384 .
obo:WBPhenotype_0002377 a rdfs:Class ;
rdfs:label "mRNA poly-A tail length increased" ;
rdfs:comment "Animals exhibit one or more mRNAs with increased length of the 3' polyadenine tail, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001827 .
obo:GO_0007409 a rdfs:Class ;
rdfs:label "axonogenesis" ;
rdfs:comment "De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells." ;
rdfs:subClassOf obo:GO_0048812 .
obo:GO_0022618 a rdfs:Class ;
rdfs:label "protein-RNA complex assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." ;
rdfs:subClassOf obo:GO_0065003 , obo:GO_0071826 .
obo:CHEBI_747204 a rdfs:Class ;
rdfs:label "reference compound" ;
rdfs:comment "Any well-characterized compound that serves as a standard for the identification, quantification, calibration, or quality control of substances in scientific analysis." ;
rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_51086 .
obo:GO_0006910 a rdfs:Class ;
rdfs:label "phagocytosis, recognition" ;
rdfs:comment "The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell." ;
rdfs:subClassOf obo:GO_0008037 .
obo:WBPhenotype_0001676 a rdfs:Class ;
rdfs:label "touch receptor cell morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or composition of any neuron within the class of sensory neurons responsible for relaying mechanical stimuli to the animal compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000905 .
obo:WBPhenotype_0000992 a rdfs:Class ;
rdfs:label "high sodium chloride concentration osmotic avoidance defective" ;
rdfs:comment "Failure to execute the characteristic response to high concentrations of sodium chloride solution. C. elegans typically avoids high concentrations of sodium chloride solution." ;
rdfs:subClassOf obo:WBPhenotype_0000249 , obo:WBPhenotype_0001453 .
obo:WBPhenotype_0000379 a rdfs:Class ;
rdfs:label "head notched" ;
rdfs:comment "The most anterior portion of the animal contains a V-shaped indentation." ;
rdfs:subClassOf obo:WBPhenotype_0000071 .
obo:WBPhenotype_0001148 a rdfs:Class ;
rdfs:label "polar body reabsorbed early emb" ;
rdfs:comment "Polar body is reabsorbed in the one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0000777 .
obo:WBPhenotype_0002675 a rdfs:Class ;
rdfs:label "glycerol levels variant"@en ;
rdfs:comment "Any variation in the levels of glycerol throughout the body of the animal as compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:GO_0031347 a rdfs:Class ;
rdfs:label "regulation of defense response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a defense response." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080134 .
obo:WBPhenotype_0000739 a rdfs:Class ;
rdfs:label "DNA damage response variant" ;
rdfs:comment "Variations in the activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000142 .
obo:WBPhenotype_0002541 a rdfs:Class ;
rdfs:label "radiation induced germ cell apoptosis resistant"@en ;
rdfs:comment "Programmed cell death of germ cells caused by exposure to ionizing energy occurs to a lesser extent than it does in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001850 .
obo:WBPhenotype_0000432 a rdfs:Class ;
rdfs:label "male copulatory structure absent" ;
rdfs:comment "Animals lack the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000430 .
obo:PATO_0000276 a rdfs:Class ;
rdfs:label "brood size" ;
rdfs:comment "A reproductive quality inhering in the young of an animal by virtue of their number." ;
rdfs:subClassOf obo:PATO_0001496 .
obo:WBPhenotype_0002477 a rdfs:Class ;
rdfs:label "ribosome localization variant" ;
rdfs:comment "Any variation in the subcellular localization of the ribosome compared to control. The ribosome is an intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA)." ;
rdfs:subClassOf obo:WBPhenotype_0002098 .
obo:WBPhenotype_0001639 a rdfs:Class ;
rdfs:label "roaming reduced" ;
rdfs:comment "Animals exhibit a decrease in their high-speed movement in the forward direction with brief backward movement compared to control. In C. elegans, Animals do not move more than a few body lengths from their starting position and searches occur locally with pivoting behavior." ;
rdfs:subClassOf obo:WBPhenotype_0000238 , obo:WBPhenotype_0001213 , obo:WBPhenotype_0002315 .
obo:GO_0051306 a rdfs:Class ;
rdfs:label "mitotic sister chromatid separation" ;
rdfs:comment "The process in which sister chromatids are physically detached from each other during mitosis." ;
rdfs:subClassOf obo:GO_0051304 , obo:GO_1903047 .
obo:GO_2000026 a rdfs:Class ;
rdfs:label "regulation of multicellular organismal development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of multicellular organismal development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0051239 , obo:GO_0065007 .
obo:GO_0048729 a rdfs:Class ;
rdfs:label "tissue morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a tissue are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_18254 a rdfs:Class ;
rdfs:label "ribonucleoside" ;
rdfs:comment "Any nucleoside where the sugar component is D-ribose." ;
rdfs:subClassOf obo:CHEBI_33838 , obo:CHEBI_47019 .
obo:WBPhenotype_0001224 a rdfs:Class ;
rdfs:label "axon outgrowth variant" ;
rdfs:comment "Any variation in the processes that govern the extension of axons compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000572 .
obo:WBPhenotype_0000386 a rdfs:Class ;
rdfs:label "genotoxic chemical induced apoptosis variant" ;
rdfs:comment "Programmed cell death of germ cells caused by exposure to DNA-damaging chemical agents does not occur to the same extent as it does in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002152 .
obo:GO_0048024 a rdfs:Class ;
rdfs:label "regulation of mRNA splicing, via spliceosome" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism." ;
rdfs:subClassOf obo:GO_0043484 , obo:GO_0050684 , obo:GO_0065007 .
obo:WBPhenotype_0001434 a rdfs:Class ;
rdfs:label "chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific chemical concentration gradient compared to control. Directed movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ;
rdfs:subClassOf obo:WBPhenotype_0001040 .
obo:GO_0010965 a rdfs:Class ;
rdfs:label "regulation of mitotic sister chromatid separation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905818 .
obo:CHEBI_33697 a rdfs:Class ;
rdfs:label "ribonucleic acid" ;
rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." ;
rdfs:subClassOf obo:CHEBI_33696 .
obo:WBPhenotype_0002182 a rdfs:Class ;
rdfs:label "reactive oxygen species homeostasis variant" ;
rdfs:comment "Animals exhibit variations in endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000577 .
obo:GO_0010938 a rdfs:Class ;
rdfs:label "cytoplasmic microtubule depolymerization" ;
rdfs:comment "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." ;
rdfs:subClassOf obo:GO_0007019 , obo:GO_0031122 .
obo:PATO_0001795 a rdfs:Class ;
rdfs:label "increased coiling" ;
rdfs:comment "A coiling which is relatively high." ;
rdfs:subClassOf obo:PATO_0000404 , obo:PATO_0002305 .
obo:CHEBI_35524 a rdfs:Class ;
rdfs:label "sympathomimetic agent" ;
rdfs:comment "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." ;
rdfs:subClassOf obo:CHEBI_37962 .
obo:GO_0022607 a rdfs:Class ;
rdfs:label "cellular component assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a cellular component." ;
rdfs:subClassOf obo:GO_0016043 .
obo:WBPhenotype_0002506 a rdfs:Class ;
rdfs:label "pathogen infection clearance rate increased"@en ;
rdfs:comment "Infected animals exhibit an increased rate of clearance of pathogen infection compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0002505 .
obo:WBPhenotype_0002570 a rdfs:Class ;
rdfs:label "embryonic arrest during gastrulation"@en ;
rdfs:comment "Cessation of development during the gastrulation stage of embryonic development. In C. elegans, gastrulation occurs 100-290 minutes after first cleavage at 20 degrees Centigrade when the embryo develops from 28 cells to 421 cells (during the proliferating embryo life stage)." ;
rdfs:subClassOf obo:WBPhenotype_0000867 .
obo:GO_1902679 a rdfs:Class ;
rdfs:label "negative regulation of RNA biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010558 , obo:GO_0051253 , obo:GO_0065007 , obo:GO_2001141 .
obo:GO_0140029 a rdfs:Class ;
rdfs:label "exocytic process" ;
rdfs:comment "The cellular processes that contribute to exocytosis." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0050896 a rdfs:Class ;
rdfs:label "response to stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CHEBI_77282 a rdfs:Class ;
rdfs:label "dexamisole" ;
rdfs:comment "A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has R configuration." ;
rdfs:subClassOf obo:CHEBI_77278 .
obo:GO_1901609 a rdfs:Class ;
rdfs:label "negative regulation of vesicle transport along microtubule" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0065007 , obo:GO_1901608 .
obo:WBPhenotype_0000964 a rdfs:Class ;
rdfs:label "DMPP resistant" ;
rdfs:comment "Animals fail to respond to the concentration of DMPP that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000681 , obo:WBPhenotype_0001502 .
obo:WBPhenotype_0001895 a rdfs:Class ;
rdfs:label "parental chromosome mixing defective" ;
rdfs:comment "Parental chromosomes fail to undergo appropriate mixing upon pronuclear fusion resulting in a zygotic nucleus in which parental genomes remain segregated." ;
rdfs:subClassOf obo:WBPhenotype_0001138 .
obo:GO_0043005 a rdfs:Class ;
rdfs:label "neuron projection" ;
rdfs:comment "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." ;
rdfs:subClassOf obo:GO_0120025 .
obo:CHEBI_27026 a rdfs:Class ;
rdfs:label "toxin" ;
rdfs:comment "Poisonous substance produced by a biological organism such as a microbe, animal or plant." ;
rdfs:subClassOf obo:CHEBI_25212 , obo:CHEBI_64909 .
obo:PATO_0000380 a rdfs:Class ;
rdfs:label "increased frequency" ;
rdfs:comment "A frequency which is relatively high." ;
rdfs:subClassOf obo:PATO_0000044 , obo:PATO_0055003 .
obo:WBPhenotype_0001375 a rdfs:Class ;
rdfs:label "transgene expression undetectable" ;
rdfs:comment "The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection." ;
rdfs:subClassOf obo:WBPhenotype_0001278 .
obo:WBPhenotype_0001614 a rdfs:Class ;
rdfs:label "anticonvulsant response variant" ;
rdfs:comment "Animals exhibit variations in their response to a specific anticonvulsant compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:GO_1903746 a rdfs:Class ;
rdfs:label "positive regulation of nematode pharyngeal pumping" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of nematode pharyngeal pumping." ;
rdfs:subClassOf obo:GO_0043051 , obo:GO_0065007 , obo:GO_1904000 .
obo:WBPhenotype_0002142 a rdfs:Class ;
rdfs:label "mitochondrial respiratory chain variant" ;
rdfs:comment "The activity, composition, or organization of the complexes of the electron transport chain, embedded in the inner mitochondrial membrane, differ from controls." ;
rdfs:subClassOf obo:WBPhenotype_0001282 .
obo:GO_1903109 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial transcription" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of transcription occurring in the mitochondrion." ;
rdfs:subClassOf obo:GO_0045893 , obo:GO_0065007 , obo:GO_1903108 .
obo:CHEBI_76663 a rdfs:Class ;
rdfs:label "EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor" ;
rdfs:comment "A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*)." ;
rdfs:subClassOf obo:CHEBI_76834 .
obo:GO_0048066 a rdfs:Class ;
rdfs:label "developmental pigmentation" ;
rdfs:comment "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." ;
rdfs:subClassOf obo:GO_0043473 .
obo:CHEBI_35230 a rdfs:Class ;
rdfs:label "fossil fuel" ;
rdfs:comment "A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth." ;
rdfs:subClassOf obo:CHEBI_33292 .
obo:WBPhenotype_0002451 a rdfs:Class ;
rdfs:label "enhanced burst pharyngeal pumping response to light" ;
rdfs:comment "Animals exhibit an enhanced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a greater extent than in controls." ;
rdfs:subClassOf obo:WBPhenotype_0002450 .
obo:GO_0006906 a rdfs:Class ;
rdfs:label "vesicle fusion" ;
rdfs:comment "Fusion of the membrane of a transport vesicle with its target membrane." ;
rdfs:subClassOf obo:GO_0016050 , obo:GO_0090174 .
obo:WBPhenotype_0001455 a rdfs:Class ;
rdfs:label "odorant negative chemotaxis variant" ;
rdfs:comment "Animals exhibit variations through directed movement, in response to repellant volatile organic chemicals, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000481 , obo:WBPhenotype_0001048 .
obo:WBPhenotype_0002564 a rdfs:Class ;
rdfs:label "associative memory phenotype"@en ;
rdfs:comment "Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000517 , obo:WBPhenotype_0000738 .
obo:CHEBI_48560 a rdfs:Class ;
rdfs:label "dopaminergic agent" ;
rdfs:comment "A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons." ;
rdfs:subClassOf obo:CHEBI_35942 .
obo:GO_0014041 a rdfs:Class ;
rdfs:label "regulation of neuron maturation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." ;
rdfs:subClassOf obo:GO_0045664 , obo:GO_0065007 , obo:GO_1903429 .
obo:WBPhenotype_0000845 a rdfs:Class ;
rdfs:label "levamisole response variant" ;
rdfs:comment "Animals exhibit variations in the response to the addition of levamisole compared to that observed in control animals. Levamisole is a cholinergic agonist." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:WBPhenotype_0000786 a rdfs:Class ;
rdfs:label "body axis pigmentation variant" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency along a particular body axis compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000278 .
obo:GO_1903307 a rdfs:Class ;
rdfs:label "positive regulation of regulated secretory pathway" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of regulated secretory pathway." ;
rdfs:subClassOf obo:GO_0045921 , obo:GO_0065007 , obo:GO_1903305 .
obo:WBPhenotype_0002408 a rdfs:Class ;
rdfs:label "cytokinesis variant" ;
rdfs:comment "Any variation that disrupts the cytoplasmic division of a cell during development compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:PATO_0002112 a rdfs:Class ;
rdfs:label "perforate" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer's having a hole or holes, especially a row or array of small holes." ;
rdfs:subClassOf obo:PATO_0002014 .
obo:WBPhenotype_0002445 a rdfs:Class ;
rdfs:label "extra and ectopic hypodermis" ;
rdfs:comment "Animals have one or more extra hypodermal cells, which are present in places they are normally not found, when compared to the number and location of these cells in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001303 .
obo:WBPhenotype_0001445 a rdfs:Class ;
rdfs:label "sodium acetate adaptation defective" ;
rdfs:comment "Animals do not exhibit characteristic chemoattractive desensitization to sodium acetate in a time-concentration dependent and reversible manner compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001444 .
obo:CHEBI_67079 a rdfs:Class ;
rdfs:label "anti-inflammatory agent" ;
rdfs:comment "Any compound that has anti-inflammatory effects." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:CHEBI_747325 a rdfs:Class ;
rdfs:label "additive" ;
rdfs:comment "a role for a chemical additive to a mixture" ;
rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_51086 .
obo:GO_0070134 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial translational initiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." ;
rdfs:subClassOf obo:GO_0045948 , obo:GO_0065007 , obo:GO_0070131 , obo:GO_0070132 .
obo:GO_0060322 a rdfs:Class ;
rdfs:label "head development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." ;
rdfs:subClassOf obo:GO_0048856 .
obo:WBPhenotype_0000905 a rdfs:Class ;
rdfs:label "neuron morphology variant" ;
rdfs:comment "Animals display variations in the structure or organization of components of the neuronal cell internal to the cell itself or in relation to the cellular environment compared to control. A neuron is a major cell type of nervous tissue specialized for transmission of information in the form of patterns of impulses." ;
rdfs:subClassOf obo:WBPhenotype_0000604 , obo:WBPhenotype_0002108 .
obo:WBPhenotype_0000874 a rdfs:Class ;
rdfs:label "G2 checkpoint variant" ;
rdfs:comment "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G2 phase of the mitotic cell cycle just before entry into M phase, nuclear division, compared to control cells." ;
rdfs:subClassOf obo:WBPhenotype_0000741 , obo:WBPhenotype_0001743 .
obo:GO_0016460 a rdfs:Class ;
rdfs:label "myosin II complex" ;
rdfs:comment "A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures." ;
rdfs:subClassOf obo:GO_0016459 .
obo:CHEBI_76976 a rdfs:Class ;
rdfs:label "bacterial xenobiotic metabolite" ;
rdfs:comment "Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria." ;
rdfs:subClassOf obo:CHEBI_76206 , obo:CHEBI_76969 .
obo:GO_0051716 a rdfs:Class ;
rdfs:label "cellular response to stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0050896 .
obo:WBPhenotype_0001882 a rdfs:Class ;
rdfs:label "aneuploidy" ;
rdfs:comment "Any variation in the number of chromosomes in a cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000773 .
obo:WBPhenotype_0000959 a rdfs:Class ;
rdfs:label "retrovesicular ganglion development variant" ;
rdfs:comment "Any variation in the progression of the ganglion which lies at the anterior limit of the ventral nerve cord, near the ventral ganglion and nerve ring in the head posterior to the excretory pore over time from its initial formation to its mature form compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000943 .
obo:GO_0036211 a rdfs:Class ;
rdfs:label "protein modification process" ;
rdfs:comment "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." ;
rdfs:subClassOf obo:GO_0019538 , obo:GO_0043412 .
obo:WBPhenotype_0000880 a rdfs:Class ;
rdfs:label "axon development variant" ;
rdfs:comment "Any variation in the processes that influence the generation of neuronal extensions, that carry efferent (outgoing) action potentials from the cell body towards target cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000944 .
obo:CHEBI_38101 a rdfs:Class ;
rdfs:label "organonitrogen heterocyclic compound" ;
rdfs:comment "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_35352 .
obo:WBPhenotype_0001692 a rdfs:Class ;
rdfs:label "pheromone induced larval display defective" ;
rdfs:comment "Animals are not induced to display surface antigens by exposure to pheromone as observed for Bristol N2 animals." ;
rdfs:subClassOf obo:WBPhenotype_0001687 .
obo:PATO_0001769 a rdfs:Class ;
rdfs:label "positional polarity" ;
rdfs:comment "A positional quality inhering in a bearer by virtue of the bearer's location of features or characteristics along an axis." ;
rdfs:subClassOf obo:PATO_0000140 .
obo:GO_0006793 a rdfs:Class ;
rdfs:label "phosphorus metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus." ;
rdfs:subClassOf obo:GO_0008152 .
obo:WBPhenotype_0001094 a rdfs:Class ;
rdfs:label "obsolete NaCl response variant" ;
rdfs:comment "OBSOLETE. Organismal response to NaCl differs from control animals." .
obo:WBPhenotype_0000198 a rdfs:Class ;
rdfs:label "obsolete vulval cell induction abnormal" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000519 a rdfs:Class ;
rdfs:label "physiology phenotype" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal functions and activities or be able to perceive and respond to stimuli compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000886 .
obo:PATO_0001453 a rdfs:Class ;
rdfs:label "detached from" ;
rdfs:comment "An attachment quality inhering in a bearer by virtue of the bearer's lacking connection or association with another entity." ;
rdfs:subClassOf obo:PATO_0001435 .
obo:GO_0031667 a rdfs:Class ;
rdfs:label "response to nutrient levels" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients." ;
rdfs:subClassOf obo:GO_0050896 .
obo:GO_0000262 a rdfs:Class ;
rdfs:label "mitochondrial chromosome" ;
rdfs:comment "A chromosome found in the mitochondrion of a eukaryotic cell." ;
rdfs:subClassOf obo:GO_0005694 .
obo:WBPhenotype_0001733 a rdfs:Class ;
rdfs:label "pheromone suppressed pumping defective" ;
rdfs:comment "Animals treated with pheromone do not exhibit a decrease in pumping rate similar to that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001287 .
obo:CHEBI_17489 a rdfs:Class ;
rdfs:label "3',5'-cyclic AMP" ;
rdfs:comment "A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_19834 , obo:CHEBI_61296 .
obo:GO_0048489 a rdfs:Class ;
rdfs:label "synaptic vesicle transport" ;
rdfs:comment "The directed movement of synaptic vesicles." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 , obo:GO_0051650 , obo:GO_0097479 .
obo:WBPhenotype_0000583 a rdfs:Class ;
rdfs:label "dumpy" ;
rdfs:comment "Worms are shorter and stouter than control animals at the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0001726 , obo:WBPhenotype_0001727 .
obo:CHEBI_33513 a rdfs:Class ;
rdfs:label "alkaline earth cation" ;
rdfs:subClassOf obo:CHEBI_25213 , obo:CHEBI_33299 .
obo:GO_1903180 a rdfs:Class ;
rdfs:label "negative regulation of dopamine biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0045963 , obo:GO_0065007 , obo:GO_1903179 .
obo:PATO_0000141 a rdfs:Class ;
rdfs:label "structure" ;
rdfs:comment "A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:WBPhenotype_0000624 a rdfs:Class ;
rdfs:label "reproductive system development variant" ;
rdfs:comment "Any variation in the progression of the reproductive system over time, from its formation to its mature state compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000530 .
obo:CHEBI_76206 a rdfs:Class ;
rdfs:label "xenobiotic metabolite" ;
rdfs:comment "Any metabolite produced by metabolism of a xenobiotic compound." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:CHEBI_33570 a rdfs:Class ;
rdfs:label "benzenediols" ;
rdfs:subClassOf obo:CHEBI_33853 .
obo:GO_1901859 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial DNA metabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process." ;
rdfs:subClassOf obo:GO_0051053 , obo:GO_0065007 , obo:GO_1901858 .
obo:WBPhenotype_0001990 a rdfs:Class ;
rdfs:label "hypoxia resistant" ;
rdfs:comment "Animals fail to respond to low amounts of oxygen that elicit a response in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002423 .
obo:WBPhenotype_0000599 a rdfs:Class ;
rdfs:label "coelomic system morphology variant" ;
rdfs:comment "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the coelomic system, compared to control. The coelom is the fluid compartment that is in contact with internal organ." ;
rdfs:subClassOf obo:WBPhenotype_0000534 .
obo:GO_0045892 a rdfs:Class ;
rdfs:label "negative regulation of DNA-templated transcription" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription." ;
rdfs:subClassOf obo:GO_0006355 , obo:GO_0065007 , obo:GO_1902679 .
obo:WBPhenotype_0000032 a rdfs:Class ;
rdfs:label "sick" ;
rdfs:comment "Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc." ;
rdfs:subClassOf obo:WBPhenotype_0000030 .
obo:WBPhenotype_0000559 a rdfs:Class ;
rdfs:label "calcium channel modulator hypersensitive" ;
rdfs:comment "Animals respond to a calcium channel modulator at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0000558 .
obo:GO_0044848 a rdfs:Class ;
rdfs:label "biological phase" ;
rdfs:comment "A distinct period or stage in a biological process or cycle." ;
rdfs:subClassOf obo:GO_0008150 .
obo:WBPhenotype_0000832 a rdfs:Class ;
rdfs:label "C lineage variant" ;
rdfs:comment "The descendants of the C blastomere exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000824 .
obo:GO_0031410 a rdfs:Class ;
rdfs:label "cytoplasmic vesicle" ;
rdfs:comment "A vesicle found in the cytoplasm of a cell." ;
rdfs:subClassOf obo:GO_0031982 , obo:GO_0097708 .
obo:WBPhenotype_0002634 a rdfs:Class ;
rdfs:label "ER stress resistant"@en ;
rdfs:comment "Animals exhibit a resistance to endoplasmic reticulum (ER) stressors such as an accumulation of unfolded proteins or the presence of chemicals that induce ER stress, such as dithiothreitol (DDT) or tunicamycin, compared to controls. This may mean that animals fare better than controls in terms of survival or some metric of health when exposed to an inducer of ER stress." ;
rdfs:subClassOf obo:WBPhenotype_0001485 .
obo:GO_0040008 a rdfs:Class ;
rdfs:label "regulation of growth" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:WBPhenotype_0001040 a rdfs:Class ;
rdfs:label "chemosensory response variant" ;
rdfs:comment "Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000523 , obo:WBPhenotype_0001049 .
obo:WBls_0000821 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during L4 larval stage"@en ;
rdfs:comment "A C. elegans life stage that occurs during the L4 larval life stage" ;
rdfs:subClassOf obo:WBls_0000817 .
obo:GO_0007051 a rdfs:Class ;
rdfs:label "spindle organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart." ;
rdfs:subClassOf obo:GO_0000226 , obo:GO_0022402 .
obo:PATO_0000060 a rdfs:Class ;
rdfs:label "spatial pattern" ;
rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's exhibiting repetition of placement of its parts." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:GO_0060629 a rdfs:Class ;
rdfs:label "regulation of homologous chromosome segregation" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." ;
rdfs:subClassOf obo:GO_0051983 , obo:GO_0065007 , obo:GO_2000241 .
obo:WBPhenotype_0002124 a rdfs:Class ;
rdfs:label "circumferential actin bundles disorganized" ;
rdfs:comment "The distribution or presence of actin in circumferential actin bundles (CFB) differs from that observed in control animals. Contraction of CFBs provide the driving force for epidermal elongation." ;
rdfs:subClassOf obo:WBPhenotype_0001587 .
obo:GO_0050658 a rdfs:Class ;
rdfs:label "RNA transport" ;
rdfs:comment "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0050657 , obo:GO_0051236 .
obo:GO_0018992 a rdfs:Class ;
rdfs:label "germ-line sex determination" ;
rdfs:comment "The determination of sex and sexual phenotype in an organism's germ line." ;
rdfs:subClassOf obo:GO_0007530 .
obo:CHEBI_36920 a rdfs:Class ;
rdfs:label "antimony oxoacid" ;
rdfs:subClassOf obo:CHEBI_33408 , obo:CHEBI_50007 .
obo:WBPhenotype_0000948 a rdfs:Class ;
rdfs:label "cuticle morphology variant" ;
rdfs:comment "Any variation in the appearance or structure of the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000912 , obo:WBPhenotype_0002558 .
obo:WBbt_0008115 a rdfs:Class ;
rdfs:label "ventral cord blast cell" ;
rdfs:comment "Blast cell lying ventrolaterally in the late embryo and L1 larval stage which divides during the late L1 larva in stereotypical reiterated fashion to give rise to many motor neurons which begin function in the ventral cord and preanal ganglion of the early L2 larva, as well as hypodermal cells (which fuse into hyp7) and a series of programmed cell deaths. In addition, the Pn.p daughters of P3 through P8 lineages persist without fusing into the hyp7 syncytium until mid L3 stage when they can be induced to divide further to produce vulval epithelial cells (vulA - vulF) or more hyp7 cells. P0 is also known as W." ;
rdfs:subClassOf obo:WBbt_0006783 .
obo:WBPhenotype_0002238 a rdfs:Class ;
rdfs:label "increased levels of reactive oxygen species" ;
rdfs:comment "Animals exhibit increased endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002182 .
obo:CHEBI_134249 a rdfs:Class ;
rdfs:label "alkanesulfonate oxoanion" ;
rdfs:comment "An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups." ;
rdfs:subClassOf obo:CHEBI_33554 .
obo:CHEBI_76779 a rdfs:Class ;
rdfs:label "EC 3.4.21.26 (prolyl oligopeptidase) inhibitor" ;
rdfs:comment "Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26)." ;
rdfs:subClassOf obo:CHEBI_5924 .
obo:WBPhenotype_0000159 a rdfs:Class ;
rdfs:label "obsolete dauer arrest variant" ;
rdfs:comment "OBSOLETE: Animals exhibit variations in the entry/exit into a state of arrested tissue development during the dauer larval stage in response to harsh environmental conditions, compared to control. In C. elegans, the dauer larva enters a state of arrest in which no developmental changes occur, until the animal finds more suitable growing conditions, or until it spontaneously shifts back into a normal developmental schedule. (WormAtlas)." .
obo:CHEBI_25213 a rdfs:Class ;
rdfs:label "metal cation" ;
rdfs:subClassOf obo:CHEBI_23906 , obo:CHEBI_36915 .
obo:WBPhenotype_0000863 a rdfs:Class ;
rdfs:label "male fertility reduced" ;
rdfs:comment "Males exhibit a reduction in the production of new individuals owing to defects in sperm competence and/or function compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000784 , obo:WBPhenotype_0001384 .
obo:WBPhenotype_0000791 a rdfs:Class ;
rdfs:label "nose resistant to fluoxetine" ;
rdfs:comment "The nose of an animal fails to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000790 .
obo:CHEBI_37015 a rdfs:Class ;
rdfs:label "ribonucleoside 5'-phosphate" ;
rdfs:subClassOf obo:CHEBI_16701 , obo:CHEBI_26561 .
obo:CHEBI_2580 a rdfs:Class ;
rdfs:label "unsaturated fatty acid anion" ;
rdfs:comment "Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:GO_0006629 a rdfs:Class ;
rdfs:label "lipid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." ;
rdfs:subClassOf obo:GO_0044238 .
obo:WBPhenotype_0001483 a rdfs:Class ;
rdfs:label "late stage egg laid" ;
rdfs:comment "The eggs being deposited by adults are of a later developmental stage, compared to control. In C. elegans, this is likely to be a consequence of delayed active egg-laying periods." ;
rdfs:subClassOf obo:WBPhenotype_0000438 , obo:WBPhenotype_0000545 .
obo:WBPhenotype_0000280 a rdfs:Class ;
rdfs:label "breaks in alae" ;
rdfs:comment "The small linear ridges running along the lateral lines of the cuticle, lengthwise along the body, contain gaps as opposed to a continuous arrangement (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001412 .
obo:GO_0010771 a rdfs:Class ;
rdfs:label "negative regulation of cell morphogenesis" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0022604 , obo:GO_0065007 .
obo:GO_0140053 a rdfs:Class ;
rdfs:label "mitochondrial gene expression" ;
rdfs:comment "The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." ;
rdfs:subClassOf obo:GO_0010467 .
obo:WBPhenotype_0002272 a rdfs:Class ;
rdfs:label "protein carbonylation variant" ;
rdfs:comment "Animals exhibit variations in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone." ;
rdfs:subClassOf obo:WBPhenotype_0001382 .
obo:CHEBI_76764 a rdfs:Class ;
rdfs:label "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor" ;
rdfs:comment "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." ;
rdfs:subClassOf obo:CHEBI_76759 .
obo:CHEBI_59698 a rdfs:Class ;
rdfs:label "phosphoric acids" ;
rdfs:comment "Compounds containing one or more phosphoric acid units." ;
rdfs:subClassOf obo:CHEBI_33457 .
obo:CHEBI_23888 a rdfs:Class ;
rdfs:label "drug" ;
rdfs:comment "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." ;
rdfs:subClassOf obo:CHEBI_52217 .
obo:CHEBI_145798 a rdfs:Class ;
rdfs:label "ouabain(1-)" ;
rdfs:comment "An organic anion that is the conjugate base of ouabain resulting from the deprotonation of the furanone moiety; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:CHEBI_33966 a rdfs:Class ;
rdfs:label "elemental silver" ;
rdfs:subClassOf obo:CHEBI_33964 .
obo:WBPhenotype_0000057 a rdfs:Class ;
rdfs:label "early larval lethal" ;
rdfs:comment "Animals die during early larval development. In C.elegans, this occurs during the L1- L2 larval stages of the life cycle." ;
rdfs:subClassOf obo:WBPhenotype_0000054 .
obo:CHEBI_37577 a rdfs:Class ;
rdfs:label "heteroatomic molecular entity" ;
rdfs:comment "A molecular entity consisting of two or more chemical elements." ;
rdfs:subClassOf obo:CHEBI_36357 .
obo:WBPhenotype_0000508 a rdfs:Class ;
rdfs:label "nonsense mRNA accumulation" ;
rdfs:comment "Animals exhibit a decrease in the regulated breakdown of mRNA transcripts in which an amino-acid codon has changed to a premature stop codon and the 3 prime end is not protected by a poly(A) tail." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:GO_0050806 a rdfs:Class ;
rdfs:label "positive regulation of synaptic transmission" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." ;
rdfs:subClassOf obo:GO_0010647 , obo:GO_0023056 , obo:GO_0050804 , obo:GO_0065007 .
obo:GO_0043242 a rdfs:Class ;
rdfs:label "negative regulation of protein-containing complex disassembly" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ;
rdfs:subClassOf obo:GO_0043244 , obo:GO_0051129 , obo:GO_0065007 .
obo:WBPhenotype_0000176 a rdfs:Class ;
rdfs:label "satiety behavior variant" ;
rdfs:comment "Any variation in the specific actions or reactions of an animal after completion of feeding, typically after a fast, compared to that observed in control animals. In C. elegans worms become behaviorally quiescent and cease feeding and moving when sated." ;
rdfs:subClassOf obo:WBPhenotype_0000659 .
obo:WBPhenotype_0000548 a rdfs:Class ;
rdfs:label "muscle dystrophy" ;
rdfs:comment "Progressive degeneration of muscle." ;
rdfs:subClassOf obo:WBPhenotype_0000611 .
obo:CHEBI_51277 a rdfs:Class ;
rdfs:label "thioester" ;
rdfs:comment "A compound of general formula RC(=O)SR'. Compare with thionoester, RC(=S)OR'." ;
rdfs:subClassOf obo:CHEBI_26959 , obo:CHEBI_36586 .
obo:GO_1901994 a rdfs:Class ;
rdfs:label "negative regulation of meiotic cell cycle phase transition" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition." ;
rdfs:subClassOf obo:GO_0051447 , obo:GO_0065007 , obo:GO_1901988 , obo:GO_1901993 .
obo:GO_0040040 a rdfs:Class ;
rdfs:label "thermosensory behavior" ;
rdfs:comment "Behavior that is dependent upon the sensation of temperature." ;
rdfs:subClassOf obo:GO_0007610 , obo:GO_0009266 .
obo:WBPhenotype_0000368 a rdfs:Class ;
rdfs:label "one point five fold arrest emb" ;
rdfs:comment "Cessation of development that normally occurs in C. elegans 420-460 min after the first embryonic cleavage at 20C, the stage between the comma and 2-fold embryo." ;
rdfs:subClassOf obo:WBPhenotype_0000864 .
obo:WBPhenotype_0000821 a rdfs:Class ;
rdfs:label "sexually dimorphic behavior variant" ;
rdfs:comment "Animals exhibit variations in sex-specific behaviors compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:WBPhenotype_0001332 a rdfs:Class ;
rdfs:label "vesicle number variant" ;
rdfs:comment "Animals display variations in the number of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001671 .
obo:GO_0090296 a rdfs:Class ;
rdfs:label "regulation of mitochondrial DNA replication" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090329 , obo:GO_1901858 .
obo:GO_0010455 a rdfs:Class ;
rdfs:label "positive regulation of cell fate commitment" ;
rdfs:comment "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ;
rdfs:subClassOf obo:GO_0010453 , obo:GO_0045597 , obo:GO_0065007 .
obo:WBPhenotype_0002552 a rdfs:Class ;
rdfs:label "cell phenotype"@en ;
rdfs:comment "A phenotype affecting a particular cell." ;
rdfs:subClassOf obo:WBPhenotype_0002551 .
obo:GO_0023019 a rdfs:Class ;
rdfs:label "signal transduction involved in regulation of gene expression" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." ;
rdfs:subClassOf obo:GO_0007165 .
obo:GO_0007028 a rdfs:Class ;
rdfs:label "cytoplasm organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." ;
rdfs:subClassOf obo:GO_0016043 .
obo:WBPhenotype_0000100 a rdfs:Class ;
rdfs:label "cell UV response variant" ;
rdfs:comment "Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000142 , obo:WBPhenotype_0000143 .
obo:WBPhenotype_0001687 a rdfs:Class ;
rdfs:label "surface antigenicity variant" ;
rdfs:comment "Cuticles of animals or cuticular extracts exhibit an altered pattern of antibody binding compared to Bristol N2 animals of the same developmental stage." ;
rdfs:subClassOf obo:WBPhenotype_0001688 .
obo:WBPhenotype_0002399 a rdfs:Class ;
rdfs:label "neurotransmitter response variant" ;
rdfs:comment "Animals exhibit variations in their response to a specific neurotransmitter compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:WBPhenotype_0001130 a rdfs:Class ;
rdfs:label "cytokinesis fails early emb" ;
rdfs:comment "Cells of the embryo attempt to divide but fail to form two daughter cells." ;
rdfs:subClassOf obo:WBPhenotype_0001078 , obo:WBPhenotype_0002391 .
obo:GO_0065007 a rdfs:Class ;
rdfs:label "biological regulation" ;
rdfs:comment "Any process that modulates a measurable attribute of any biological process, quality or function." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_0046826 a rdfs:Class ;
rdfs:label "negative regulation of protein export from nucleus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0046823 , obo:GO_0046825 , obo:GO_0051457 , obo:GO_0065007 , obo:GO_0090317 .
obo:WBPhenotype_0000689 a rdfs:Class ;
rdfs:label "maternal sterile" ;
rdfs:comment "Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." ;
rdfs:subClassOf obo:WBPhenotype_0000694 .
obo:WBPhenotype_0002164 a rdfs:Class ;
rdfs:label "innate immune response variant" ;
rdfs:comment "Animals exhibit variations in their defense responses that are mediated by germline encoded components that directly recognize components of potential pathogens." ;
rdfs:subClassOf obo:WBPhenotype_0001012 .
obo:GO_0098916 a rdfs:Class ;
rdfs:label "anterograde trans-synaptic signaling" ;
rdfs:comment "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." ;
rdfs:subClassOf obo:GO_0099537 .
obo:WBPhenotype_0001546 a rdfs:Class ;
rdfs:label "dauer resistance to harsh conditions variant" ;
rdfs:comment "Variations which lead to the decreased ability of dauer larva to survive at extreme conditions, such as high or low temperatures, the presence of dilute acids, detergents, anesthetics, or even fixatives, compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0002527 .
obo:CHEBI_50312 a rdfs:Class ;
rdfs:label "onium compound" ;
rdfs:subClassOf obo:CHEBI_37577 .
obo:WBPhenotype_0002664 a rdfs:Class ;
rdfs:label "RNA subcellular localization variant"@en ;
rdfs:comment "Any variation in the placement of RNA within in a cell or cellular compartment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000113 .
obo:GO_0032879 a rdfs:Class ;
rdfs:label "regulation of localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:GO_0098687 a rdfs:Class ;
rdfs:label "chromosomal region" ;
rdfs:comment "Any subdivision of a chromosome along its length." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0000780 a rdfs:Class ;
rdfs:label "shaker" ;
rdfs:comment "Animals rotate back and forth around their longitudinal axes." ;
rdfs:subClassOf obo:WBPhenotype_0001701 .
obo:CHEBI_37175 a rdfs:Class ;
rdfs:label "organic hydride" ;
rdfs:subClassOf obo:CHEBI_33692 .
obo:GO_0030397 a rdfs:Class ;
rdfs:label "membrane disassembly" ;
rdfs:comment "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0061024 .
obo:WBPhenotype_0002611 a rdfs:Class ;
rdfs:label "meiotic cytoplasmic streaming defective"@en ;
rdfs:comment "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is impaired." ;
rdfs:subClassOf obo:WBPhenotype_0000360 , obo:WBPhenotype_0002613 .
obo:WBPhenotype_0000856 a rdfs:Class ;
rdfs:label "excretory gland cell development variant" ;
rdfs:comment "Any variation in the progression of a gland cell of the secretory-excretory system over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000620 , obo:WBPhenotype_0000813 .
obo:CL_0000066 a rdfs:Class ;
rdfs:label "epithelial cell" ;
rdfs:comment "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." ;
rdfs:subClassOf obo:CL_0000255 .
obo:WBPhenotype_0002467 a rdfs:Class ;
rdfs:label "male reproductive longevity extended" ;
rdfs:comment "Males continue to sire progeny significantly past the time reproduction stops in control animals or show a slower decline in mating efficiency compared to age-matched control males." ;
rdfs:subClassOf obo:WBPhenotype_0001739 .
obo:GO_1901976 a rdfs:Class ;
rdfs:label "regulation of cell cycle checkpoint" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell cycle checkpoint." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901987 , obo:GO_1902531 .
obo:CHEBI_60334 a rdfs:Class ;
rdfs:label "peptide anion" ;
rdfs:comment "An anion formed by deprotonation of at least one peptide carboxy group." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:CHEBI_33358 a rdfs:Class ;
rdfs:label "cobalt group element atom" ;
rdfs:subClassOf obo:CHEBI_33561 .
obo:WBPhenotype_0001568 a rdfs:Class ;
rdfs:label "mRNA export variant" ;
rdfs:comment "Any variation in the export of mRNA from the cell nucleus compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000114 , obo:WBPhenotype_0001706 .
obo:GO_0051649 a rdfs:Class ;
rdfs:label "establishment of localization in cell" ;
rdfs:comment "Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." ;
rdfs:subClassOf obo:GO_0051234 .
obo:CHEBI_76807 a rdfs:Class ;
rdfs:label "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor" ;
rdfs:comment "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." ;
rdfs:subClassOf obo:CHEBI_76764 .
obo:CHEBI_2555 a rdfs:Class ;
rdfs:label "aldicarb" ;
rdfs:comment "The oxime carbamate resulting from the addition of 2-methyl-2-(methylsulfanyl)propanaldoxime to methyl isocyanate. A member of the class of oxime carbamate insecticides, aldicarb is a mixture of E and Z isomers; it is not known which isomer is more active." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_23003 .
obo:WBPhenotype_0002135 a rdfs:Class ;
rdfs:label "organism predator response variant" ;
rdfs:comment "Predator-prey interactions differ from that observed in control interactions." ;
rdfs:subClassOf obo:WBPhenotype_0000738 .
obo:GO_0051099 a rdfs:Class ;
rdfs:label "positive regulation of binding" ;
rdfs:comment "Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf obo:GO_0044093 , obo:GO_0051098 , obo:GO_0065007 .
obo:GO_0040028 a rdfs:Class ;
rdfs:label "regulation of vulval development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:CHEBI_35350 a rdfs:Class ;
rdfs:label "hydroxy steroid" ;
rdfs:subClassOf obo:CHEBI_33822 , obo:CHEBI_35341 .
obo:CHEBI_39221 a rdfs:Class ;
rdfs:label "macrolide pesticide" ;
rdfs:subClassOf obo:CHEBI_25105 .
obo:WBPhenotype_0000975 a rdfs:Class ;
rdfs:label "neuronal sheath cell physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for a neuronal sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000974 , obo:WBPhenotype_0000986 .
obo:WBPhenotype_0000148 a rdfs:Class ;
rdfs:label "starvation induced dauer formation variant" ;
rdfs:comment "Animals exhibit variations in the entry into the dauer stage when exposed to nutrient poor conditions that induce dauer formation in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000147 , obo:WBPhenotype_0001539 .
obo:GO_0051276 a rdfs:Class ;
rdfs:label "chromosome organization" ;
rdfs:comment "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." ;
rdfs:subClassOf obo:GO_0006996 .
obo:CHEBI_32954 a rdfs:Class ;
rdfs:label "sodium acetate" ;
rdfs:subClassOf obo:CHEBI_38700 .
obo:GO_0060467 a rdfs:Class ;
rdfs:label "negative regulation of fertilization" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080154 , obo:GO_2000242 .
obo:WBPhenotype_0006001 a rdfs:Class ;
rdfs:label "squashed vulva" ;
rdfs:comment "The apparent partial collapse of the vulval invagination and the elongation of central vulva cells often leading to a flattened appearance." ;
rdfs:subClassOf obo:WBPhenotype_0000510 .
obo:WBPhenotype_0001591 a rdfs:Class ;
rdfs:label "microtubule polymerization variant" ;
rdfs:comment "Any variation that alters the characteristic addition of tubulin heterodimers to one or both ends of a microtubule compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001369 , obo:WBPhenotype_0001588 .
obo:GO_1903313 a rdfs:Class ;
rdfs:label "positive regulation of mRNA metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051254 , obo:GO_0065007 , obo:GO_1903311 .
obo:WBPhenotype_0000111 a rdfs:Class ;
rdfs:label "pattern of gene expression variant" ;
rdfs:comment "Any variation in the cellular or subcellular distribution of a gene product compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:WBPhenotype_0002066 a rdfs:Class ;
rdfs:label "basement membrane gap expansion variant" ;
rdfs:comment "Animals display variations in the manner in which an opening in the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) expands to make way for intertissue connections, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002065 .
obo:GO_1900102 a rdfs:Class ;
rdfs:label "negative regulation of endoplasmic reticulum unfolded protein response" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900101 , obo:GO_1902532 , obo:GO_1903573 .
obo:CHEBI_60242 a rdfs:Class ;
rdfs:label "monovalent inorganic cation" ;
rdfs:comment "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." ;
rdfs:subClassOf obo:CHEBI_36915 .
obo:CHEBI_28260 a rdfs:Class ;
rdfs:label "galactose" ;
rdfs:comment "An aldohexose that is the C-4 epimer of glucose." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33917 .
obo:WBPhenotype_0001230 a rdfs:Class ;
rdfs:label "anterior cell migration defective" ;
rdfs:comment "The orderly movement of cells along the anterior axis of the animal is abolished, misdirected or incomplete compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000594 .
obo:WBPhenotype_0001099 a rdfs:Class ;
rdfs:label "nose twisted" ;
rdfs:comment "The extreme anterior part of the body appears distorted, usually due to uncharacteristic winding." ;
rdfs:subClassOf obo:WBPhenotype_0000321 .
obo:CHEBI_25442 a rdfs:Class ;
rdfs:label "mycotoxin" ;
rdfs:comment "Poisonous substance produced by fungi." ;
rdfs:subClassOf obo:CHEBI_27026 , obo:CHEBI_76946 .
obo:CHEBI_36343 a rdfs:Class ;
rdfs:label "composite particle" ;
rdfs:comment "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." ;
rdfs:subClassOf obo:CHEBI_36342 .
obo:CHEBI_64641 a rdfs:Class ;
rdfs:label "divalent inorganic cation" ;
rdfs:comment "An inorganic cation with a valency of two." ;
rdfs:subClassOf obo:CHEBI_36915 .
obo:CHEBI_59871 a rdfs:Class ;
rdfs:label "D-alpha-amino acid zwitterion" ;
rdfs:comment "Zwitterionic form of a D-α-amino acid having an anionic carboxy group and a protonated amino group." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:WBPhenotype_0002175 a rdfs:Class ;
rdfs:label "cell number increased" ;
rdfs:comment "The number of cells in the organism is increased compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002173 .
obo:GO_0048786 a rdfs:Class ;
rdfs:label "presynaptic active zone" ;
rdfs:comment "A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_138000 a rdfs:Class ;
rdfs:label "3-(1-methylpyrrolidin-2-yl)pyridine" ;
rdfs:comment "An N-alkylpyrrolidine that consists of N-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2." ;
rdfs:subClassOf obo:CHEBI_26416 , obo:CHEBI_26456 , obo:CHEBI_46775 .
obo:WBPhenotype_0002071 a rdfs:Class ;
rdfs:label "body lengthening response to muscimol variant" ;
rdfs:comment "The length of the animal does not increase to the same extent as observed for control animals, in response to exposure to muscimol." ;
rdfs:subClassOf obo:WBPhenotype_0002047 .
obo:GO_0005775 a rdfs:Class ;
rdfs:label "vacuolar lumen" ;
rdfs:comment "The volume enclosed within the vacuolar membrane." ;
rdfs:subClassOf obo:GO_0031974 , obo:GO_0070013 .
obo:WBPhenotype_0001397 a rdfs:Class ;
rdfs:label "necrotic cell death increased" ;
rdfs:comment "Animals exhibit an increase in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000415 .
obo:WBPhenotype_0000916 a rdfs:Class ;
rdfs:label "excretory cell morphology variant" ;
rdfs:comment "Any variation in the morphological appearance of the excretory cell compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000533 , obo:WBPhenotype_0000601 .
obo:GO_0051051 a rdfs:Class ;
rdfs:label "negative regulation of transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0051049 , obo:GO_0065007 .
obo:GO_0098763 a rdfs:Class ;
rdfs:label "mitotic cell cycle phase" ;
rdfs:comment "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ;
rdfs:subClassOf obo:GO_0022403 .
obo:GO_0090063 a rdfs:Class ;
rdfs:label "positive regulation of microtubule nucleation" ;
rdfs:comment "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." ;
rdfs:subClassOf obo:GO_0010968 , obo:GO_0031116 , obo:GO_0065007 .
obo:GO_0032989 a rdfs:Class ;
rdfs:label "cellular anatomical entity morphogenesis" ;
rdfs:comment "The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system." ;
rdfs:subClassOf obo:GO_0016043 .
obo:WBbt_0007850 a rdfs:Class ;
rdfs:label "male" ;
rdfs:comment "Gonochoristic organism that can produce male gametes." ;
rdfs:subClassOf obo:WBbt_0007833 .
obo:GO_0007275 a rdfs:Class ;
rdfs:label "multicellular organism development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ;
rdfs:subClassOf obo:GO_0032501 , obo:GO_0048856 .
obo:WBPhenotype_0000728 a rdfs:Class ;
rdfs:label "exocytosis variant" ;
rdfs:comment "Variations in the process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000258 , obo:WBPhenotype_0001752 .
obo:WBPhenotype_0002456 a rdfs:Class ;
rdfs:label "calcium response to light variant" ;
rdfs:comment "Animals exhibit variations in the changes in calcium levels in response to light compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0001897 , obo:WBPhenotype_0002170 .
obo:WBPhenotype_0000202 a rdfs:Class ;
rdfs:label "alae variant" ;
rdfs:comment "Any variation in the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000201 .
obo:WBPhenotype_0001315 a rdfs:Class ;
rdfs:label "electrophysiology phenotype" ;
rdfs:comment "Animals exhibit variations in the electrical properties of any of its cells or tissues compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000519 .
obo:GO_1900248 a rdfs:Class ;
rdfs:label "negative regulation of cytoplasmic translational elongation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation." ;
rdfs:subClassOf obo:GO_0045900 , obo:GO_0065007 , obo:GO_1900247 , obo:GO_2000766 .
obo:GO_0043065 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0043068 , obo:GO_0065007 .
obo:WBls_0000109 a rdfs:Class ;
rdfs:label "L4 larval stage" ;
rdfs:comment "The fourth stage larva of nematodes." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000105 .
obo:GO_0001558 a rdfs:Class ;
rdfs:label "regulation of cell growth" ;
rdfs:comment "Any process that modulates the frequency, rate, extent or direction of cell growth." ;
rdfs:subClassOf obo:GO_0040008 , obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0097479 a rdfs:Class ;
rdfs:label "synaptic vesicle localization" ;
rdfs:comment "Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051648 .
obo:GO_0044238 a rdfs:Class ;
rdfs:label "primary metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ;
rdfs:subClassOf obo:GO_0008152 .
obo:CHEBI_33300 a rdfs:Class ;
rdfs:label "pnictogen" ;
rdfs:comment "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." ;
rdfs:subClassOf obo:CHEBI_33560 .
obo:WBPhenotype_0002388 a rdfs:Class ;
rdfs:label "metaphase variant" ;
rdfs:comment "Any variation in the second stage of cell division, between prophase and anaphase, during which the chromosomes become attached to the spindle fibers." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:GO_0030031 a rdfs:Class ;
rdfs:label "cell projection assembly" ;
rdfs:comment "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0030030 .
obo:CHEBI_33307 a rdfs:Class ;
rdfs:label "thiocarboxylic acid" ;
rdfs:comment "An organic acid in which one or both oxygens of a carboxy group have been replaced by divalent sulfur." ;
rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_64709 .
obo:WBPhenotype_0002048 a rdfs:Class ;
rdfs:label "abamectin resistant" ;
rdfs:comment "Animals survive longer, or do not respond to the same degree as control animals under similar conditions of abamectin exposure." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0002049 .
obo:WBPhenotype_0001386 a rdfs:Class ;
rdfs:label "fertilization defective hermaphrodite" ;
rdfs:comment "Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) in adult hermaphrodites during sexual reproduction." ;
rdfs:subClassOf obo:WBPhenotype_0000983 .
obo:GO_0060281 a rdfs:Class ;
rdfs:label "regulation of oocyte development" ;
rdfs:comment "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905879 .
obo:WBPhenotype_0002600 a rdfs:Class ;
rdfs:label "short-term habituation phenotype"@en ;
rdfs:comment "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s)." ;
rdfs:subClassOf obo:WBPhenotype_0000626 .
obo:WBbt_0008590 a rdfs:Class ;
rdfs:label "P lineage cell" ;
rdfs:comment "A cell that is the P embryonic blast cell or is a lineal descendant of P." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:GO_0005764 a rdfs:Class ;
rdfs:label "lysosome" ;
rdfs:comment "A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions." ;
rdfs:subClassOf obo:GO_0000323 .
obo:GO_0060429 a rdfs:Class ;
rdfs:label "epithelium development" ;
rdfs:comment "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." ;
rdfs:subClassOf obo:GO_0009888 .
obo:GO_0001708 a rdfs:Class ;
rdfs:label "cell fate specification" ;
rdfs:comment "The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate." ;
rdfs:subClassOf obo:GO_0048869 .
obo:GO_0045165 a rdfs:Class ;
rdfs:label "cell fate commitment" ;
rdfs:comment "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." ;
rdfs:subClassOf obo:GO_0048869 .
obo:GO_1901987 a rdfs:Class ;
rdfs:label "regulation of cell cycle phase transition" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell cycle phase transition." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0065007 .
obo:GO_0097193 a rdfs:Class ;
rdfs:label "intrinsic apoptotic signaling pathway" ;
rdfs:comment "The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP)." ;
rdfs:subClassOf obo:GO_0035556 , obo:GO_0097190 .
obo:GO_1900073 a rdfs:Class ;
rdfs:label "regulation of neuromuscular synaptic transmission" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 .
obo:GO_0010260 a rdfs:Class ;
rdfs:label "obsolete animal organ senescence" ;
rdfs:comment "OBSOLETE. The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism." .
obo:GO_0051224 a rdfs:Class ;
rdfs:label "negative regulation of protein transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051051 , obo:GO_0051223 , obo:GO_0065007 , obo:GO_1903828 , obo:GO_1904950 .
obo:GO_0006996 a rdfs:Class ;
rdfs:label "organelle organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0016043 .
obo:CHEBI_36380 a rdfs:Class ;
rdfs:label "emetan" ;
rdfs:subClassOf obo:CHEBI_24921 , obo:CHEBI_24922 , obo:CHEBI_38515 .
obo:WBPhenotype_0001607 a rdfs:Class ;
rdfs:label "paralysis response to ethanol hypersensitive" ;
rdfs:comment "Animals become paralyzed in response to ethanol at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001606 .
obo:WBPhenotype_0000649 a rdfs:Class ;
rdfs:label "vulva location variant" ;
rdfs:comment "Any variation in the male's ability to locate his partner's vulva when backing along the ventral side of the partner during mating compared to control. In C. elegans the male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate." ;
rdfs:subClassOf obo:WBPhenotype_0004006 .
obo:GO_0051100 a rdfs:Class ;
rdfs:label "negative regulation of binding" ;
rdfs:comment "Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf obo:GO_0044092 , obo:GO_0051098 , obo:GO_0065007 .
obo:WBPhenotype_0000588 a rdfs:Class ;
rdfs:label "obsolete no male variantity scored" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0000609 a rdfs:Class ;
rdfs:label "excretory secretory system physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the excretory/secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000575 .
obo:WBls_0000810 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during comma embryo"@en ;
rdfs:comment "A C. elegans life stage that occurs during the comma embryo life stage" ;
rdfs:subClassOf obo:WBls_0000805 .
obo:GO_0036194 a rdfs:Class ;
rdfs:label "muscle cell projection" ;
rdfs:comment "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." ;
rdfs:subClassOf obo:GO_0120025 .
obo:WBPhenotype_0002025 a rdfs:Class ;
rdfs:label "cell size decreased" ;
rdfs:comment "The diameter, volume, or area taken up by a cell differs from that measured in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000533 .
obo:GO_0022409 a rdfs:Class ;
rdfs:label "positive regulation of cell-cell adhesion" ;
rdfs:comment "Any process that activates or increases the rate or extent of cell adhesion to another cell." ;
rdfs:subClassOf obo:GO_0022407 , obo:GO_0045785 , obo:GO_0065007 .
obo:WBPhenotype_0002224 a rdfs:Class ;
rdfs:label "mercury hypersensitive" ;
rdfs:comment "Animals respond to mercury at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000591 , obo:WBPhenotype_0001918 .
obo:WBPhenotype_0000213 a rdfs:Class ;
rdfs:label "zygotic development variant" ;
rdfs:comment "Variations in the progression of a zygote from formation (gamete fusion) to just prior to the first cell division compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000749 .
obo:WBPhenotype_0001326 a rdfs:Class ;
rdfs:label "cell gamma ray response variant" ;
rdfs:comment "Cells exhibit variations in their response to gamma ray radiation compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000497 , obo:WBPhenotype_0001324 .
obo:GO_0050770 a rdfs:Class ;
rdfs:label "regulation of axonogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron." ;
rdfs:subClassOf obo:GO_0010975 , obo:GO_0022603 , obo:GO_0065007 .
obo:CHEBI_16134 a rdfs:Class ;
rdfs:label "ammonia" ;
rdfs:comment "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_138675 , obo:CHEBI_35107 , obo:CHEBI_37176 .
obo:WBPhenotype_0000021 a rdfs:Class ;
rdfs:label "squat" ;
rdfs:comment "Squat animals are dumpy as homozygotes, but roll as heterozygotes." ;
rdfs:subClassOf obo:WBPhenotype_0000231 .
obo:WBbt_0004778 a rdfs:Class ;
rdfs:label "H0L" ;
rdfs:comment "Seam hypodermal cell" ;
rdfs:subClassOf obo:WBbt_0005753 , obo:WBbt_0007028 .
obo:WBbt_0005735 a rdfs:Class ;
rdfs:label "nervous system" ;
rdfs:comment "Complement of nervous tissue (neurones, nerves, receptors and support cells) serving to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities." ;
rdfs:subClassOf obo:WBbt_0005746 .
obo:GO_0010556 a rdfs:Class ;
rdfs:label "regulation of macromolecule biosynthetic process" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0060255 , obo:GO_0065007 .
obo:WBPhenotype_0000421 a rdfs:Class ;
rdfs:label "levamisole resistant" ;
rdfs:comment "Animals fail to respond to the concentration of levamisole that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans resistance to levamisole is often assayed via body contraction response, ventral tail curling response etc." ;
rdfs:subClassOf obo:WBPhenotype_0000845 , obo:WBPhenotype_0001502 , obo:WBPhenotype_0001578 .
obo:GO_0009893 a rdfs:Class ;
rdfs:label "positive regulation of metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0048522 , obo:GO_0065007 .
obo:WBPhenotype_0002441 a rdfs:Class ;
rdfs:label "pharyngeal inter-pump interval increased" ;
rdfs:comment "The time between two pumps of the pharynx is increased compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001006 .
obo:WBPhenotype_0000397 a rdfs:Class ;
rdfs:label "harsh body touch resistant" ;
rdfs:comment "Animals do not respond to prodding with a fine platinum wire or similar tool compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000456 .
obo:GO_0043054 a rdfs:Class ;
rdfs:label "dauer exit" ;
rdfs:comment "Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development." ;
rdfs:subClassOf obo:GO_0071981 .
obo:CHEBI_35479 a rdfs:Class ;
rdfs:label "alkali metal salt" ;
rdfs:subClassOf obo:CHEBI_24866 , obo:CHEBI_33296 .
obo:GO_0006979 a rdfs:Class ;
rdfs:label "response to oxidative stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0006950 .
obo:WBls_0000003 a rdfs:Class ;
rdfs:label "embryo Ce" ;
rdfs:comment "The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching." ;
rdfs:subClassOf obo:WBls_0000102 , obo:WBls_0000803 .
obo:CHEBI_27208 a rdfs:Class ;
rdfs:label "unsaturated fatty acid" ;
rdfs:comment "Any fatty acid containing at least one C=C or C≡C bond." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:GO_1902804 a rdfs:Class ;
rdfs:label "negative regulation of synaptic vesicle transport" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0051051 , obo:GO_0065007 , obo:GO_1902803 .
obo:WBPhenotype_0000747 a rdfs:Class ;
rdfs:label "pharyngeal contraction defective" ;
rdfs:comment "Any defects in the muscle contractions that control feeding. Contractions are necessary for bacterial uptake from the surrounding environment." ;
rdfs:subClassOf obo:WBPhenotype_0000980 .
obo:GO_0034764 a rdfs:Class ;
rdfs:label "positive regulation of transmembrane transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0034762 , obo:GO_0048522 , obo:GO_0051050 , obo:GO_0065007 .
obo:GO_0042752 a rdfs:Class ;
rdfs:label "regulation of circadian rhythm" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:WBPhenotype_0001894 a rdfs:Class ;
rdfs:label "nuclear number variant" ;
rdfs:comment "Animals exhibit variations in the number of nuclei contained in a particular cell type compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000504 .
obo:CHEBI_37739 a rdfs:Class ;
rdfs:label "glycerophospholipid" ;
rdfs:comment "Any glycerolipid having a phosphate group ester-linked to a terminal carbon of the glycerol backbone." ;
rdfs:subClassOf obo:CHEBI_16247 , obo:CHEBI_35741 .
obo:WBbt_0006816 a rdfs:Class ;
rdfs:label "ciliated neuron" ;
rdfs:comment "neuron type, neurons that have ciliated nerve endings." ;
rdfs:subClassOf obo:WBbt_0003679 .
obo:BFO_0000031 a rdfs:Class ;
rdfs:label "generically dependent continuant"@en ;
rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:GO_1902103 a rdfs:Class ;
rdfs:label "negative regulation of metaphase/anaphase transition of meiotic cell cycle" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901994 , obo:GO_1902100 , obo:GO_1902102 , obo:GO_1905133 .
obo:WBPhenotype_0001826 a rdfs:Class ;
rdfs:label "RNA degradation variant" ;
rdfs:comment "Variations in the regulated breakdown of RNA species via the action of cellular enzymes (RNases) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000028 , obo:WBPhenotype_0001827 .
obo:WBPhenotype_0001213 a rdfs:Class ;
rdfs:label "locomotion reduced" ;
rdfs:comment "Animals exhibit a decrease in any parameter used to measure locomotion compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000641 .
obo:WBPhenotype_0001466 a rdfs:Class ;
rdfs:label "AWA odorant chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWA sensory neuron in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000265 .
obo:WBPhenotype_0000317 a rdfs:Class ;
rdfs:label "head withdrawal defective" ;
rdfs:comment "Animals are deficient in the foraging response in which an animal quickly pulls its head away from a stimulus to the nose (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000315 .
obo:CHEBI_30616 a rdfs:Class ;
rdfs:label "ATP(4-)" ;
rdfs:comment "A nucleoside triphosphate(4−) obtained by global deprotonation of the triphosphate OH groups of ATP; major species present at pH 7.3." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_61557 .
obo:WBbt_0004216 a rdfs:Class ;
rdfs:label "Z1.apppaaaa" ;
rdfs:comment "Anterior spermathecae" ;
rdfs:subClassOf obo:WBbt_0007816 .
obo:WBPhenotype_0001423 a rdfs:Class ;
rdfs:label "coelomocyte physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the coelomocyte to carry out its normal functions or activities, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000536 , obo:WBPhenotype_0000607 .
obo:WBbt_0005772 a rdfs:Class ;
rdfs:label "intestine" ;
rdfs:comment "A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages." ;
rdfs:subClassOf obo:WBbt_0003760 .
obo:GO_0042423 a rdfs:Class ;
rdfs:label "catecholamine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ;
rdfs:subClassOf obo:GO_0006584 , obo:GO_0009713 , obo:GO_0042401 .
obo:WBPhenotype_0002067 a rdfs:Class ;
rdfs:label "apical constriction variant" ;
rdfs:comment "Animals differ from control animals in cortical actomyocin dynamics leading to internalization of endodermal precursor cells during gastrulation." ;
rdfs:subClassOf obo:WBPhenotype_0000047 .
obo:CHEBI_50733 a rdfs:Class ;
rdfs:label "nutraceutical" ;
rdfs:comment "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0009310 a rdfs:Class ;
rdfs:label "amine catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0009308 .
obo:WBPhenotype_0001856 a rdfs:Class ;
rdfs:label "ivermectin response variant" ;
rdfs:comment "Animals exhibit variations in their response to ivermectin, an agonist of glutamate-gated chloride channels, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000631 , obo:WBPhenotype_0001852 .
obo:WBPhenotype_0000808 a rdfs:Class ;
rdfs:label "K lineage variant" ;
rdfs:comment "The descendants of the K precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000825 .
obo:GO_0005938 a rdfs:Class ;
rdfs:label "cell cortex" ;
rdfs:comment "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." ;
rdfs:subClassOf obo:GO_0005737 .
obo:GO_0016887 a rdfs:Class ;
rdfs:label "ATP hydrolysis activity" ;
rdfs:comment "Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient." ;
rdfs:subClassOf obo:GO_0017111 .
obo:CHEBI_35570 a rdfs:Class ;
rdfs:label "mancude organic heterobicyclic parent" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_35571 .
obo:CHEBI_36893 a rdfs:Class ;
rdfs:label "elemental iodine" ;
rdfs:subClassOf obo:CHEBI_33434 .
obo:GO_0160315 a rdfs:Class ;
rdfs:label "endosomal intralumenal vesicle lumen" ;
rdfs:comment "The volume enclosed by the membrane of an intraluminal vesicle within an endosome." ;
rdfs:subClassOf obo:GO_0031974 , obo:GO_0070013 .
obo:WBPhenotype_0002440 a rdfs:Class ;
rdfs:label "sperm fertility defective" ;
rdfs:comment "Any perturbation that renders sperm incompetent at fertilizing an oocyte." ;
rdfs:subClassOf obo:WBPhenotype_0001384 .
obo:CL_0000670 a rdfs:Class ;
rdfs:label "primordial germ cell" ;
rdfs:comment "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." ;
rdfs:subClassOf obo:CL_0000039 , obo:CL_0000219 .
obo:WBPhenotype_0000594 a rdfs:Class ;
rdfs:label "cell migration variant" ;
rdfs:comment "Any variation in the orderly movement of a cell from one site to another." ;
rdfs:subClassOf obo:WBPhenotype_0000529 .
obo:GO_1903179 a rdfs:Class ;
rdfs:label "regulation of dopamine biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dopamine biosynthetic process." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0042053 , obo:GO_0065007 .
obo:GO_0045948 a rdfs:Class ;
rdfs:label "positive regulation of translational initiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translational initiation." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0045727 , obo:GO_0065007 .
obo:WBPhenotype_0002235 a rdfs:Class ;
rdfs:label "growth defective on low phosphate media" ;
rdfs:comment "Animals are unable to grow on media depleted of phosphate." ;
rdfs:subClassOf obo:WBPhenotype_0000576 .
obo:PATO_0001928 a rdfs:Class ;
rdfs:label "blistered" ;
rdfs:comment "A texture quality inhering in a bearer by virtue of a local accumulation of fluid underneath the surface of the bearer." ;
rdfs:subClassOf obo:PATO_0000150 .
obo:CHEBI_37164 a rdfs:Class ;
rdfs:label "homopolysaccharide" ;
rdfs:comment "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." ;
rdfs:subClassOf obo:CHEBI_18154 .
obo:CHEBI_24858 a rdfs:Class ;
rdfs:label "iodide salt" ;
rdfs:subClassOf obo:CHEBI_24860 , obo:CHEBI_33958 .
obo:WBPhenotype_0000187 a rdfs:Class ;
rdfs:label "egg round" ;
rdfs:comment "The overall structure or appearance of fertilized oocytes that are laid has every part of their surface equidistant from the center." ;
rdfs:subClassOf obo:WBPhenotype_0000373 .
obo:GO_0035046 a rdfs:Class ;
rdfs:label "pronuclear migration" ;
rdfs:comment "The directed movement of the male and female pronuclei towards each other prior to their fusion." ;
rdfs:subClassOf obo:GO_0007097 .
obo:GO_0006983 a rdfs:Class ;
rdfs:label "ER overload response" ;
rdfs:comment "The series of molecular signals initiated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB." ;
rdfs:subClassOf obo:GO_0006984 , obo:GO_0034976 , obo:GO_0071216 .
obo:GO_0042755 a rdfs:Class ;
rdfs:label "eating behavior" ;
rdfs:comment "The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue." ;
rdfs:subClassOf obo:GO_0007631 .
obo:WBPhenotype_0001535 a rdfs:Class ;
rdfs:label "deirid sensillum morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC." ;
rdfs:subClassOf obo:WBPhenotype_0000299 .
obo:GO_0030029 a rdfs:Class ;
rdfs:label "actin filament-based process" ;
rdfs:comment "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." ;
rdfs:subClassOf obo:GO_0009987 .
obo:WBPhenotype_0000797 a rdfs:Class ;
rdfs:label "posterior body behavior variant" ;
rdfs:comment "Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the tail of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000795 .
obo:CHEBI_38366 a rdfs:Class ;
rdfs:label "trans-pent-2-enoic acid" ;
rdfs:subClassOf obo:CHEBI_35939 .
obo:WBPhenotype_0000630 a rdfs:Class ;
rdfs:label "quinine chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to the bitter tastant quinine, as defined by control animals. In C. elegans, quinine is typically repellent." ;
rdfs:subClassOf obo:WBPhenotype_0001449 , obo:WBPhenotype_0001454 .
obo:PATO_0001852 a rdfs:Class ;
rdfs:label "dislocated" ;
rdfs:comment "A positional quality inhering in a bearer by virtue of the bearer's being out of its usual or proper place, or position due to it being physically moved from the normal location." ;
rdfs:subClassOf obo:PATO_0002181 .
obo:WBPhenotype_0000711 a rdfs:Class ;
rdfs:label "organism hypersensitive ionizing radiation" ;
rdfs:comment "Animals exhibit increased sensitivity to the effects of ion producing radiation compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000686 .
obo:WBPhenotype_0000270 a rdfs:Class ;
rdfs:label "pleiotropic defects severe early emb" ;
rdfs:comment "Seemingly unrelated variations that concurrently occur during early embryonic development compared to control animals. In C. elegans, this can include multiple pronuclei, aberrant cytoplasmic texture, decrease in overall pace of development and osmotic sensitivity." ;
rdfs:subClassOf obo:WBPhenotype_0001007 .
obo:GO_0044819 a rdfs:Class ;
rdfs:label "mitotic G1/S transition checkpoint signaling" ;
rdfs:comment "A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0007093 , obo:GO_2000134 .
obo:WBPhenotype_0002183 a rdfs:Class ;
rdfs:label "oxidative DNA damage variant" ;
rdfs:comment "Animals exhibit variations in levels of DNA damage caused by oxidative stress." ;
rdfs:subClassOf obo:WBPhenotype_0000732 .
obo:PATO_0002062 a rdfs:Class ;
rdfs:label "physical quality of a process" ;
rdfs:subClassOf obo:PATO_0001236 .
obo:CHEBI_26398 a rdfs:Class ;
rdfs:label "purine ribonucleoside triphosphate" ;
rdfs:subClassOf obo:CHEBI_17972 , obo:CHEBI_26393 .
obo:WBPhenotype_0002041 a rdfs:Class ;
rdfs:label "molt variant" ;
rdfs:comment "Animals exhibit variation in timing or ability to molt." ;
rdfs:subClassOf obo:WBPhenotype_0000750 .
obo:GO_0022402 a rdfs:Class ;
rdfs:label "cell cycle process" ;
rdfs:comment "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." ;
rdfs:subClassOf obo:GO_0009987 .
obo:PATO_0002181 a rdfs:Class ;
rdfs:label "displaced" ;
rdfs:comment "A positional quality inhering in a bearer by virtue the bearer's being changed in position." ;
rdfs:subClassOf obo:PATO_0000140 .
obo:WBPhenotype_0000161 a rdfs:Class ;
rdfs:label "nuclear rotation variant" ;
rdfs:comment "Any variation in the rotation of centrosomes and associated pronuclei in one-cell embryo, occurring as a transition between pronuclear migration and pronuclear fusion compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000749 , obo:WBPhenotype_0001028 .
obo:WBPhenotype_0001229 a rdfs:Class ;
rdfs:label "anterior neuron migration defective" ;
rdfs:comment "The orderly movement of neurons along the anterior axis of the animal is abolished, misdirected or incomplete compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001140 .
a rdfs:Class ;
rdfs:comment "An unconstrained type or object" .
obo:CHEBI_13941 a rdfs:Class ;
rdfs:label "carbamate" ;
rdfs:subClassOf obo:CHEBI_37022 .
obo:CHEBI_33366 a rdfs:Class ;
rdfs:label "copper group element atom" ;
rdfs:subClassOf obo:CHEBI_33561 .
obo:WBPhenotype_0000036 a rdfs:Class ;
rdfs:label "adult body morphology variant" ;
rdfs:comment "Any variation in the overall structure or appearance of the animal after it has completed progression through the larval stages compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000072 , obo:WBPhenotype_0000934 .
obo:GO_0007416 a rdfs:Class ;
rdfs:label "synapse assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." ;
rdfs:subClassOf obo:GO_0034329 , obo:GO_0050808 .
obo:GO_1901192 a rdfs:Class ;
rdfs:label "positive regulation of formation of translation initiation ternary complex" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex." ;
rdfs:subClassOf obo:GO_0031334 , obo:GO_0065007 , obo:GO_1901190 .
obo:GO_1904950 a rdfs:Class ;
rdfs:label "negative regulation of establishment of protein localization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0065007 , obo:GO_0070201 .
obo:CL_0000255 a rdfs:Class ;
rdfs:label "eukaryotic cell" ;
rdfs:comment "Any cell that in taxon some Eukaryota." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0090615 a rdfs:Class ;
rdfs:label "mitochondrial mRNA processing" ;
rdfs:comment "Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs." ;
rdfs:subClassOf obo:GO_0000959 , obo:GO_0000963 , obo:GO_0006397 .
obo:GO_0032938 a rdfs:Class ;
rdfs:label "negative regulation of translation in response to oxidative stress" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0032057 , obo:GO_0043556 , obo:GO_0043558 , obo:GO_0065007 .
obo:WBbt_0005821 a rdfs:Class ;
rdfs:label "vulval muscle" ;
rdfs:comment "muscle associated with hermaphrodite vulva." ;
rdfs:subClassOf obo:WBbt_0005758 , obo:WBbt_0005780 , obo:WBbt_0007810 .
obo:PATO_0000462 a rdfs:Class ;
rdfs:label "absent" ;
rdfs:comment "A quality denoting the lack of an entity." ;
rdfs:subClassOf obo:PATO_0000070 .
obo:WBPhenotype_0002481 a rdfs:Class ;
rdfs:label "heme levels decreased" ;
rdfs:comment "Animals exhibit a decrease in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring." ;
rdfs:subClassOf obo:WBPhenotype_0002480 .
obo:WBPhenotype_0002631 a rdfs:Class ;
rdfs:label "tissue edema"@en ;
rdfs:comment "Animals exhibit edema (swelling) of one or more tissues, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000520 , obo:WBPhenotype_0002556 .
obo:WBPhenotype_0000635 a rdfs:Class ;
rdfs:label "positive chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of an animal in response to chemical attractants as defined by control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001434 .
obo:GO_0080135 a rdfs:Class ;
rdfs:label "regulation of cellular response to stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 , obo:GO_0080134 .
obo:GO_0007056 a rdfs:Class ;
rdfs:label "spindle assembly involved in female meiosis" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0051225 , obo:GO_0090306 .
obo:WBPhenotype_0000487 a rdfs:Class ;
rdfs:label "colchicine resistant" ;
rdfs:comment "Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 , obo:WBPhenotype_0001502 .
obo:CHEBI_36897 a rdfs:Class ;
rdfs:label "monoatomic iodine" ;
rdfs:subClassOf obo:CHEBI_36893 .
obo:WBls_0000022 a rdfs:Class ;
rdfs:label "postembryonic Ce" ;
rdfs:comment "A developemental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until death." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000804 .
obo:WBPhenotype_0000680 a rdfs:Class ;
rdfs:label "aldicarb response variant" ;
rdfs:comment "Animals exhibit variations in their response to aldicarb compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001290 .
obo:WBPhenotype_0000025 a rdfs:Class ;
rdfs:label "blistered" ;
rdfs:comment "Fluid-filled blisters appear on the cuticle." ;
rdfs:subClassOf obo:WBPhenotype_0000948 .
obo:WBPhenotype_0001297 a rdfs:Class ;
rdfs:label "male tail development variant" ;
rdfs:comment "Any variation in the process whose specific outcome is the progression of the male tail over time, from its formation to the mature structure, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000805 .
obo:WBPhenotype_0000302 a rdfs:Class ;
rdfs:label "benzaldehyde chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to benzaldehyde as defined by control animals. In C.elegans benzaldehyde is typically attractive." ;
rdfs:subClassOf obo:WBPhenotype_0001060 , obo:WBPhenotype_0001468 .
obo:GO_0042331 a rdfs:Class ;
rdfs:label "phototaxis" ;
rdfs:comment "The directed movement of a motile cell or organism in response to light." ;
rdfs:subClassOf obo:GO_0009416 , obo:GO_0009453 .
obo:CHEBI_350546 a rdfs:Class ;
rdfs:label "serotonin(1+)" ;
rdfs:comment "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_35274 .
obo:GO_0000045 a rdfs:Class ;
rdfs:label "autophagosome assembly" ;
rdfs:comment "The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm." ;
rdfs:subClassOf obo:GO_0070925 , obo:GO_1905037 .
obo:WBPhenotype_0000447 a rdfs:Class ;
rdfs:label "adult development variant" ;
rdfs:comment "Variations in the progression of an animal over time from the end of larval stage to a mature adult compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000049 .
obo:GO_0140238 a rdfs:Class ;
rdfs:label "presynaptic endocytosis" ;
rdfs:comment "A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." ;
rdfs:subClassOf obo:GO_0006897 , obo:GO_0051649 , obo:GO_0099003 .
obo:WBPhenotype_0000704 a rdfs:Class ;
rdfs:label "excretory canal morphology variant" ;
rdfs:comment "Variations in the form or composition of structures made by the processes of the excretory canal cell compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000916 , obo:WBPhenotype_0002558 .
obo:WBbt_0008073 a rdfs:Class ;
rdfs:label "syncytium precursor" ;
rdfs:comment "cell that is mononuclear and has a strong potential to fuse with other cell(s) to form a multinucleated cell." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBPhenotype_0001859 a rdfs:Class ;
rdfs:label "Dosage compensation complex assembly variant" ;
rdfs:comment "Any variation in the aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000718 .
obo:WBPhenotype_0000295 a rdfs:Class ;
rdfs:label "thermotolerance increased" ;
rdfs:comment "Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000146 .
obo:WBPhenotype_0002115 a rdfs:Class ;
rdfs:label "suicidal" ;
rdfs:comment "Animals do not avoid, and perhaps seek, environments that result in their death. In the case of C. elegans, this behavior is exemplified by animals that tend to crawl off the plate." ;
rdfs:subClassOf obo:WBPhenotype_0000888 .
obo:GO_0045763 a rdfs:Class ;
rdfs:label "negative regulation of amino acid metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." ;
rdfs:subClassOf obo:GO_0006521 , obo:GO_0009892 , obo:GO_0065007 .
obo:CHEBI_51137 a rdfs:Class ;
rdfs:label "mianserin" ;
rdfs:comment "A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_47804 .
obo:GO_0016070 a rdfs:Class ;
rdfs:label "RNA metabolic process" ;
rdfs:comment "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ;
rdfs:subClassOf obo:GO_0090304 .
obo:WBPhenotype_0001819 a rdfs:Class ;
rdfs:label "pathogen load variant" ;
rdfs:comment "The number of pathogens associated with the animal vary from that associated with control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001012 .
obo:CHEBI_35881 a rdfs:Class ;
rdfs:label "pnictogen hydride" ;
rdfs:subClassOf obo:CHEBI_33242 , obo:CHEBI_33302 .
obo:WBPhenotype_0000742 a rdfs:Class ;
rdfs:label "DNA recombination variant" ;
rdfs:comment "Variations in the process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000732 .
obo:WBbt_0004422 a rdfs:Class ;
rdfs:label "P0" ;
rdfs:comment "Single cell zygote" ;
rdfs:subClassOf obo:WBbt_0008448 .
obo:CHEBI_38180 a rdfs:Class ;
rdfs:label "polycyclic heteroarene" ;
rdfs:subClassOf obo:CHEBI_33833 .
obo:GO_0010971 a rdfs:Class ;
rdfs:label "positive regulation of G2/M transition of mitotic cell cycle" ;
rdfs:comment "Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0010389 , obo:GO_0065007 , obo:GO_1901992 , obo:GO_1902751 .
obo:GO_0030036 a rdfs:Class ;
rdfs:label "actin cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ;
rdfs:subClassOf obo:GO_0007010 , obo:GO_0030029 .
obo:GO_0005576 a rdfs:Class ;
rdfs:label "extracellular region" ;
rdfs:comment "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0002503 a rdfs:Class ;
rdfs:label "meiotic DNA double strand break formation increased"@en ;
rdfs:comment "Animals exhibit an increase the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination." ;
rdfs:subClassOf obo:WBPhenotype_0001921 .
obo:CHEBI_75772 a rdfs:Class ;
rdfs:label "Saccharomyces cerevisiae metabolite" ;
rdfs:comment "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae )." ;
rdfs:subClassOf obo:CHEBI_76946 .
obo:CHEBI_33232 a rdfs:Class ;
rdfs:label "application" ;
rdfs:comment "Intended use of the molecular entity or part thereof by humans." ;
rdfs:subClassOf obo:CHEBI_50906 .
obo:WBPhenotype_0002492 a rdfs:Class ;
rdfs:label "ectopic body wall muscle"@en ;
rdfs:comment "Animals exhibit one or more body wall muscle cells in locations not normally found in controls." ;
rdfs:subClassOf obo:WBPhenotype_0002493 .
obo:CHEBI_33832 a rdfs:Class ;
rdfs:label "organic cyclic compound" ;
rdfs:comment "Any organic molecule that consists of atoms connected in the form of a ring." ;
rdfs:subClassOf obo:CHEBI_33595 , obo:CHEBI_72695 .
obo:WBPhenotype_0002419 a rdfs:Class ;
rdfs:label "spindle aster variant" ;
rdfs:comment "Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a cell cycle." ;
rdfs:subClassOf obo:WBPhenotype_0002414 .
obo:WBPhenotype_0000336 a rdfs:Class ;
rdfs:label "terminal bulb relaxation variant" ;
rdfs:comment "Variations in the rhythmic relaxations of the posterior pharynx (terminal bulb). In C. elegans the relaxation of the terminal bulb returns the grinder to its relaxed forward position." ;
rdfs:subClassOf obo:WBPhenotype_0000330 .
obo:WBPhenotype_0002580 a rdfs:Class ;
rdfs:label "cell position variability phenotype"@en ;
rdfs:comment "One or more cells exhibit changes in the variability of cell position, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000533 .
obo:WBPhenotype_0001848 a rdfs:Class ;
rdfs:label "tube morphogenesis variant" ;
rdfs:comment "Variations in the process by which the anatomical structures of a tube are generated and organized, compared to control. Morphogenesis pertains to the creation of form or shape." ;
rdfs:subClassOf obo:WBPhenotype_0000530 .
obo:WBPhenotype_0001235 a rdfs:Class ;
rdfs:label "cell division polarity variant" ;
rdfs:comment "Any variation in the orientation of the physical partitioning and separation of a cell into daughter cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:GO_2000808 a rdfs:Class ;
rdfs:label "negative regulation of synaptic vesicle clustering" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering." ;
rdfs:subClassOf obo:GO_0051051 , obo:GO_0065007 , obo:GO_2000807 .
obo:WBPhenotype_0001513 a rdfs:Class ;
rdfs:label "dense core vesicle exocytosis variant" ;
rdfs:comment "Variations in the process of secretion of a class of membrane-bound vesicles found inside neurons, gland cells, and some epithelial cells in which the central core appears darkly stained when viewed in thin section by electron microscopy, compared to control. Exocytosis occurs via the fusion of the vesicle with the plasma membrane of a cell (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000728 .
obo:PATO_0000402 a rdfs:Class ;
rdfs:label "branched" ;
rdfs:comment "A branchiness quality inhering in a bearer by virtue of the bearer's having branches." ;
rdfs:subClassOf obo:PATO_0002009 .
obo:WBPhenotype_0000616 a rdfs:Class ;
rdfs:label "synapse morphology variant" ;
rdfs:comment "Animals display variations in the appearance of the subcellular junctional structure composed of a presynaptic terminal directly opposite the post-synaptic target and separated by a synaptic cleft." ;
rdfs:subClassOf obo:WBPhenotype_0000604 , obo:WBPhenotype_0001657 .
obo:CHEBI_18282 a rdfs:Class ;
rdfs:label "nucleobase" ;
rdfs:comment "That part of DNA or RNA that may be involved in pairing." ;
rdfs:subClassOf obo:CHEBI_38101 .
obo:WBPhenotype_0002012 a rdfs:Class ;
rdfs:label "meiotic chromosome organization variant" ;
rdfs:comment "Any variation in the process of chromosome organization that is involved in meiosis, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000775 .
obo:WBPhenotype_0000240 a rdfs:Class ;
rdfs:label "blast cell proliferation reduced" ;
rdfs:comment "The processes governing the expansion of blast cell populations vary, such that cell populations are decreased compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000173 .
obo:GO_0055123 a rdfs:Class ;
rdfs:label "digestive system development" ;
rdfs:comment "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0048731 .
obo:WBPhenotype_0001878 a rdfs:Class ;
rdfs:label "hydroxyurea response variant" ;
rdfs:comment "Animals exhibit variations in the response to the addition of hydroxyurea compared to that observed in control animals. Hydroxyurea stops DNA from being replicated." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:GO_0061458 a rdfs:Class ;
rdfs:label "reproductive system development" ;
rdfs:comment "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." ;
rdfs:subClassOf obo:GO_0048731 .
obo:PATO_0001836 a rdfs:Class ;
rdfs:label "congested" ;
rdfs:comment "A structural quality inhering in a bearer with some kind of aperture or opening that is blocked or clogged." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:WBPhenotype_0002384 a rdfs:Class ;
rdfs:label "xenotoxicity suppressor" ;
rdfs:comment "Animals are resistant to the toxicity of an anti-infective xenobiotic such as R24. Such small molecules protect the host from bacterial infection by inducing antibacterial immune responses via the p38 MAPK pathway. These molecules tend to have toxic effects in addition to immunostimulatory activity." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:GO_0042416 a rdfs:Class ;
rdfs:label "dopamine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ;
rdfs:subClassOf obo:GO_0042417 , obo:GO_0042423 .
obo:GO_0046832 a rdfs:Class ;
rdfs:label "negative regulation of RNA export from nucleus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0032240 , obo:GO_0046823 , obo:GO_0046831 , obo:GO_0065007 .
obo:WBPhenotype_0001408 a rdfs:Class ;
rdfs:label "pattern protein expression variant" ;
rdfs:comment "Any variation in the cellular or subcellular distribution of a protein compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000112 .
obo:CHEBI_43176 a rdfs:Class ;
rdfs:label "hydroxy group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:WBPhenotype_0001953 a rdfs:Class ;
rdfs:label "nuclear fallout" ;
rdfs:comment "Nuclei have fallen out of developing germ cell compartments into the rachis." ;
rdfs:subClassOf obo:WBPhenotype_0001952 .
obo:GO_0045930 a rdfs:Class ;
rdfs:label "negative regulation of mitotic cell cycle" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0045786 , obo:GO_0065007 .
obo:GO_0003006 a rdfs:Class ;
rdfs:label "developmental process involved in reproduction" ;
rdfs:comment "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring." ;
rdfs:subClassOf obo:GO_0022414 , obo:GO_0032502 .
obo:WBPhenotype_0002461 a rdfs:Class ;
rdfs:label "pathogen adherence decreased" ;
rdfs:comment "Pathogens exhibit decreased adherence to the surface of host animals." ;
rdfs:subClassOf obo:WBPhenotype_0001415 .
obo:CHEBI_50297 a rdfs:Class ;
rdfs:label "canonical nucleotide residue" ;
rdfs:subClassOf obo:CHEBI_50319 .
obo:WBPhenotype_0001488 a rdfs:Class ;
rdfs:label "gubernaculum development variant" ;
rdfs:comment "Animals exhibit variations in the development of the sclerotic cuticle that forms the roof of the proctodeum (gubernaculum) compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001367 .
obo:WBPhenotype_0002575 a rdfs:Class ;
rdfs:label "gene expression level abnormal"@en ;
rdfs:comment "Animals exhibit abnormal gene expression levels, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000717 .
obo:CHEBI_65256 a rdfs:Class ;
rdfs:label "antimicrobial food preservative" ;
rdfs:comment "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." ;
rdfs:subClassOf obo:CHEBI_33281 , obo:CHEBI_65255 .
obo:CHEBI_35507 a rdfs:Class ;
rdfs:label "natural product fundamental parent" ;
rdfs:subClassOf obo:CHEBI_33245 .
obo:CHEBI_26666 a rdfs:Class ;
rdfs:label "short-chain fatty acid" ;
rdfs:comment "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:WBPhenotype_0000516 a rdfs:Class ;
rdfs:label "ventral cord disorganized" ;
rdfs:comment "The longitudinal nerve cord of the midbody region, connecting the nerve ring and tail ganglia, is not arranged in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000976 .
obo:GO_0032460 a rdfs:Class ;
rdfs:label "negative regulation of protein oligomerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization." ;
rdfs:subClassOf obo:GO_0031333 , obo:GO_0032459 , obo:GO_0065007 .
obo:CHEBI_64245 a rdfs:Class ;
rdfs:label "tunicamycin A1" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 12-methyltridec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33838 .
obo:WBPhenotype_0000803 a rdfs:Class ;
rdfs:label "head development variant" ;
rdfs:comment "Variations in the progression of the anterior end of the animal over time from an initial condition to a later condition compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000579 .
obo:WBPhenotype_0000256 a rdfs:Class ;
rdfs:label "amphid neuron morphology variant" ;
rdfs:comment "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." ;
rdfs:subClassOf obo:WBPhenotype_0000255 .
obo:WBPhenotype_0000453 a rdfs:Class ;
rdfs:label "body protrusions" ;
rdfs:comment "Any irregular swelling in discrete regions of the body region between the head and the tail." ;
rdfs:subClassOf obo:WBPhenotype_0000072 .
obo:PATO_0001906 a rdfs:Class ;
rdfs:label "movement quality" ;
rdfs:comment "A physical quality inhering in a bearer by virtue of the bearer's participation in movement." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:GO_0007005 a rdfs:Class ;
rdfs:label "mitochondrion organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components." ;
rdfs:subClassOf obo:GO_0006996 .
obo:GO_0007271 a rdfs:Class ;
rdfs:label "synaptic transmission, cholinergic" ;
rdfs:comment "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ;
rdfs:subClassOf obo:GO_0007268 .
obo:WBPhenotype_0002052 a rdfs:Class ;
rdfs:label "ascaroside biosynthesis defective" ;
rdfs:comment "Animals lack the ability to produce ascarosides that are capable of being produced in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002051 .
obo:CHEBI_29534 a rdfs:Class ;
rdfs:label "avermectin B1a" ;
rdfs:subClassOf obo:CHEBI_50344 .
obo:GO_0010507 a rdfs:Class ;
rdfs:label "negative regulation of autophagy" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0010506 , obo:GO_0065007 .
obo:GO_0090138 a rdfs:Class ;
rdfs:label "regulation of actin cytoskeleton organization by cell-cell adhesion" ;
rdfs:comment "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ;
rdfs:subClassOf obo:GO_0032956 , obo:GO_0098609 .
obo:WBPhenotype_0010004 a rdfs:Class ;
rdfs:label "cell corpse degradation variant" ;
rdfs:comment "Variations in the process(es) that constitute cell corpse degradation within the engulfing cell compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:GO_1904094 a rdfs:Class ;
rdfs:label "positive regulation of autophagic cell death" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of autophagic cell death." ;
rdfs:subClassOf obo:GO_0043068 , obo:GO_0065007 , obo:GO_1904092 .
obo:WBPhenotype_0000696 a rdfs:Class ;
rdfs:label "everted vulva" ;
rdfs:comment "The eversion process, in which the vulval invagination is turned inside out during the final molt, is disrupted. In C.elegans, such variations in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva)." ;
rdfs:subClassOf obo:WBPhenotype_0000695 .
obo:WBPhenotype_0000493 a rdfs:Class ;
rdfs:label "metacorpus morphology defective" ;
rdfs:comment "Any variation in the form, structure or composition of the first pharyngeal bulb compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000709 .
obo:CHEBI_76713 a rdfs:Class ;
rdfs:label "EC 4.3.* (C-N lyase) inhibitor" ;
rdfs:comment "A lyase inhibitor which inhibits the action of a C‒N lyase (EC 4.3.*.*)." ;
rdfs:subClassOf obo:CHEBI_76710 .
obo:WBPhenotype_0000325 a rdfs:Class ;
rdfs:label "arecoline hypersensitive" ;
rdfs:comment "Animals respond to arecoline at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001579 , obo:WBPhenotype_0001918 .
obo:CHEBI_33261 a rdfs:Class ;
rdfs:label "organosulfur compound" ;
rdfs:comment "An organosulfur compound is a compound containing at least one carbon-sulfur bond." ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_36962 .
obo:WBPhenotype_0002039 a rdfs:Class ;
rdfs:label "retrograde transport variant" ;
rdfs:comment "Animals exhibit variation in the directed movement of organelles or molecules along microtubules from the cell periphery in nerve cell axons to the cell body, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002563 .
obo:WBPhenotype_0000555 a rdfs:Class ;
rdfs:label "drug adaptation variant" ;
rdfs:comment "Animals show variations in their decreased responsiveness after prolonged or repeated exposure to a drug compared to that in control." ;
rdfs:subClassOf obo:WBPhenotype_0000631 .
obo:CHEBI_17996 a rdfs:Class ;
rdfs:label "chloride" ;
rdfs:comment "A halide anion formed when chlorine picks up an electron to form an an anion." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_16042 , obo:CHEBI_33432 .
obo:GO_0048843 a rdfs:Class ;
rdfs:label "negative regulation of axon extension involved in axon guidance" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance." ;
rdfs:subClassOf obo:GO_0030517 , obo:GO_0048841 , obo:GO_0050922 , obo:GO_0065007 .
obo:CHEBI_50344 a rdfs:Class ;
rdfs:label "avermectin" ;
rdfs:comment "Any of the macrolides obtained as fermentation products from the bacterium Streptomyces avermitilis and consisting of a 16-membered macrocyclic backbone that is fused both benzofuran and spiroketal functions and contains a disaccharide substituent. They have significant anthelmintic and insecticidal properties." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_25106 , obo:CHEBI_59779 .
obo:PATO_0000770 a rdfs:Class ;
rdfs:label "uncoordinated" ;
rdfs:comment "A coordination quality of inhering in a bearer by virtue of the bearer's lacking skillful and effective interaction of movement." ;
rdfs:subClassOf obo:PATO_0000188 .
obo:PATO_0001162 a rdfs:Class ;
rdfs:label "increased concentration" ;
rdfs:comment "A concentration which is higher relative to the normal or average." ;
rdfs:subClassOf obo:PATO_0000470 , obo:PATO_0001159 , obo:PATO_0002305 .
obo:WBPhenotype_0000849 a rdfs:Class ;
rdfs:label "amphid physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for an amphid to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000652 .
obo:WBPhenotype_0002265 a rdfs:Class ;
rdfs:label "lysosome-related organelle biogenesis variant" ;
rdfs:comment "Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001344 .
obo:CHEBI_26400 a rdfs:Class ;
rdfs:label "purine ribonucleotide" ;
rdfs:comment "Any ribonucleotide that has a purine nucleobase." ;
rdfs:subClassOf obo:CHEBI_26395 , obo:CHEBI_26561 .
obo:CHEBI_25810 a rdfs:Class ;
rdfs:label "oxopurine" ;
rdfs:subClassOf obo:CHEBI_26401 .
obo:CHEBI_33693 a rdfs:Class ;
rdfs:label "oxygen hydride" ;
rdfs:subClassOf obo:CHEBI_36902 .
obo:GO_0032154 a rdfs:Class ;
rdfs:label "cleavage furrow" ;
rdfs:comment "The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm." ;
rdfs:subClassOf obo:GO_0098590 .
obo:CHEBI_26167 a rdfs:Class ;
rdfs:label "polar amino acid" ;
rdfs:comment "Any amino acid whose side chain is capable of forming one or more hydrogen bonds." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:WBPhenotype_0001152 a rdfs:Class ;
rdfs:label "pronuclear migration defective early emb" ;
rdfs:comment "Pronucleus migration is abnormal in the inviable embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001151 .
obo:CHEBI_35106 a rdfs:Class ;
rdfs:label "nitrogen hydride" ;
rdfs:subClassOf obo:CHEBI_35881 , obo:CHEBI_51143 .
obo:WBPhenotype_0001889 a rdfs:Class ;
rdfs:label "body wall muscle sarcomere morphology variant" ;
rdfs:comment "Any variation in the form, structure or composition of the repeating units of a myofibrils in a muscle cell that are composed of an array of overlapping thick and thin filaments, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000926 .
obo:GO_1900006 a rdfs:Class ;
rdfs:label "positive regulation of dendrite development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dendrite development." ;
rdfs:subClassOf obo:GO_0010976 , obo:GO_0050773 , obo:GO_0051094 , obo:GO_0065007 .
obo:WBPhenotype_0001090 a rdfs:Class ;
rdfs:label "thermotolerance reduced" ;
rdfs:comment "Animals are not able to survive at temperatures above standard cultivation temperatures to the same extent as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000146 .
obo:WBbt_0005394 a rdfs:Class ;
rdfs:label "amphid neuron" ;
rdfs:comment "neuron of the amphid sensillum" ;
rdfs:subClassOf obo:WBbt_0006816 .
obo:GO_0022603 a rdfs:Class ;
rdfs:label "regulation of anatomical structure morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:CHEBI_47013 a rdfs:Class ;
rdfs:label "D-ribofuranose" ;
rdfs:comment "A ribofuranose having D-configuration." ;
rdfs:subClassOf obo:CHEBI_16988 , obo:CHEBI_46998 .
obo:CHEBI_26561 a rdfs:Class ;
rdfs:label "ribonucleotide" ;
rdfs:subClassOf obo:CHEBI_26562 , obo:CHEBI_36976 .
obo:WBPhenotype_0001960 a rdfs:Class ;
rdfs:label "spindle oscillation variant" ;
rdfs:comment "The spindle in the early embryo is aberrant in the characteristic posterior aster oscillations that occur along the transverse longitudinal axis of the spindle." ;
rdfs:subClassOf obo:WBPhenotype_0002414 .
obo:GO_1903829 a rdfs:Class ;
rdfs:label "positive regulation of protein localization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a protein localization." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0048518 , obo:GO_0065007 .
obo:WBPhenotype_0000663 a rdfs:Class ;
rdfs:label "osmotic avoidance variant" ;
rdfs:comment "Animals exhibit variations in the avoidance response to solutions of a particular osmotic strength compared to control. In C. elegans, animals typically avoid solutions of high osmotic strength." ;
rdfs:subClassOf obo:WBPhenotype_0000481 .
obo:WBPhenotype_0000505 a rdfs:Class ;
rdfs:label "male ray morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of any of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control animals. In C. elegans, nine bilateral rays project from the tail in a radial pattern with a smooth and slightly tapered appearance. Although one neuronal member of each ray sensillum is exposed to the outside, male rays rarely take up dye." ;
rdfs:subClassOf obo:WBPhenotype_0000299 , obo:WBPhenotype_0001358 .
obo:GO_0005575 a rdfs:Class ;
rdfs:label "cellular_component" ;
rdfs:comment "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." .
obo:GO_0006449 a rdfs:Class ;
rdfs:label "regulation of translational termination" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translational termination." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0043244 , obo:GO_0065007 .
obo:WBPhenotype_0000960 a rdfs:Class ;
rdfs:label "ventral ganglion development variant" ;
rdfs:comment "Any variation in the progression of the ganglion which lies ventrally beside the nerve ring in the head, just anterior of the retrovesicular ganglion over time from its initial formation to its mature form compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000943 .
obo:WBPhenotype_0000019 a rdfs:Class ;
rdfs:label "pharyngeal pumping reduced" ;
rdfs:comment "Pharyngeal pumping motion occurs at a slower rate than control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001006 .
obo:WBPhenotype_0001899 a rdfs:Class ;
rdfs:label "glutathione levels variant" ;
rdfs:comment "Animals exhibit variations in the amount of glutathione compared to control animals at a defined stage. Glutathione, the tripeptide glutamylcysteinylglycine, acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:CHEBI_37527 a rdfs:Class ;
rdfs:label "acid" ;
rdfs:comment "An acid is a molecular entity capable of donating a hydron (Brønsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:WBbt_0005750 a rdfs:Class ;
rdfs:label "socket cell" ;
rdfs:comment "An interfacial epithelial cell which forms a distal cap on a sheath cell to bind the sheath of a sensillum to the neighboring hypodermis, via adherens junctions. There is often a narrow opening through the socket from the exterior into the sheath channel, allowing ciliated dendrites to be exposed to the external environment. The socket cell functions similarly to a glial cell." ;
rdfs:subClassOf obo:WBbt_0005754 , obo:WBbt_0005762 .
obo:GO_0006260 a rdfs:Class ;
rdfs:label "DNA replication" ;
rdfs:comment "The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA." ;
rdfs:subClassOf obo:GO_0006259 .
obo:WBPhenotype_0001077 a rdfs:Class ;
rdfs:label "chromosome segregation variant karyomeres early emb" ;
rdfs:comment "Karyomeres in AB or P1 often accompanied by weak/thin wobbly spindle." ;
rdfs:subClassOf obo:WBPhenotype_0000773 , obo:WBPhenotype_0001100 .
obo:WBPhenotype_0000407 a rdfs:Class ;
rdfs:label "obsolete ray loss" ;
rdfs:comment "OBSOLETE." .
obo:WBPhenotype_0002677 a rdfs:Class ;
rdfs:label "adult-onset sterility"@en ;
rdfs:comment "Animals exhibit sterility that manifests specifically during the adult life stage" ;
rdfs:subClassOf obo:WBPhenotype_0000688 .
obo:WBPhenotype_0000382 a rdfs:Class ;
rdfs:label "serotonin reuptake inhibitor hypersensitive" ;
rdfs:comment "Animals respond to serotonin reuptake inhibitors at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000010 .
obo:WBPhenotype_0001218 a rdfs:Class ;
rdfs:label "cell death sexually dimorphic variant" ;
rdfs:comment "Animals exhibit variations in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations." ;
rdfs:subClassOf obo:WBPhenotype_0000730 .
obo:GO_0098796 a rdfs:Class ;
rdfs:label "membrane protein complex" ;
rdfs:comment "Any protein complex that is part of a membrane." ;
rdfs:subClassOf obo:GO_0032991 .
obo:WBPhenotype_0000263 a rdfs:Class ;
rdfs:label "axoneme short" ;
rdfs:comment "The microbule-based fibrillar bundle in the core of the cilium is reduced in length compared to axonemes of similar cells in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000262 .
obo:GO_2000766 a rdfs:Class ;
rdfs:label "negative regulation of cytoplasmic translation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation." ;
rdfs:subClassOf obo:GO_0017148 , obo:GO_0065007 , obo:GO_2000765 .
obo:WBbt_0006748 a rdfs:Class ;
rdfs:label "vulva" ;
rdfs:comment "female genital." ;
rdfs:subClassOf obo:WBbt_0005758 , obo:WBbt_0008422 .
obo:WBPhenotype_0002276 a rdfs:Class ;
rdfs:label "dauer lifespan shortened" ;
rdfs:comment "The life span of dauer-staged animals is shorter than that observed in control dauer animals." ;
rdfs:subClassOf obo:WBPhenotype_0001540 .
obo:CHEBI_19129 a rdfs:Class ;
rdfs:label "11alpha-hydroxy steroid" ;
rdfs:subClassOf obo:CHEBI_36841 .
obo:GO_0048880 a rdfs:Class ;
rdfs:label "sensory system development" ;
rdfs:comment "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048731 .
obo:CHEBI_48359 a rdfs:Class ;
rdfs:label "protophilic solvent" ;
rdfs:comment "Solvent that is capable of acting as a hydron (proton) acceptor." ;
rdfs:subClassOf obo:CHEBI_39142 , obo:CHEBI_48354 .
obo:CHEBI_35356 a rdfs:Class ;
rdfs:label "dicarboximide" ;
rdfs:comment "An imide in which the two acyl substituents on nitrogen are carboacyl groups." ;
rdfs:subClassOf obo:CHEBI_24782 .
obo:WBPhenotype_0000836 a rdfs:Class ;
rdfs:label "gonadal lineage variant" ;
rdfs:comment "The descendants of a gonadal precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000825 .
obo:WBPhenotype_0002059 a rdfs:Class ;
rdfs:label "pore forming toxin hypersensitive" ;
rdfs:comment "Animals respond to pore forming toxins at a lower concentration or a shorter exposure compared to control animals. Increased susceptibility to pore forming toxins (e.g. Cry5B from Bacillus thuringiensis) is often measured by a decrease in the rate of survival in the presence of pore forming toxins compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000010 , obo:WBPhenotype_0002058 .
obo:GO_1902668 a rdfs:Class ;
rdfs:label "negative regulation of axon guidance" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance." ;
rdfs:subClassOf obo:GO_0010977 , obo:GO_0050922 , obo:GO_0065007 , obo:GO_1902667 .
obo:WBPhenotype_0001163 a rdfs:Class ;
rdfs:label "pronucleus formation failure early emb" ;
rdfs:comment "Either the maternal or paternal pronucleus is absent." ;
rdfs:subClassOf obo:WBPhenotype_0001162 .
obo:PATO_0000584 a rdfs:Class ;
rdfs:label "hypertrophic" ;
rdfs:comment "An increased size quality inhering in a bearer by virtue of the bearer's exhibiting enlargement of a cell or constituent group of cells (for example, organ)." ;
rdfs:subClassOf obo:PATO_0000595 .
obo:WBPhenotype_0001628 a rdfs:Class ;
rdfs:label "locomotion rate serotonin resistant" ;
rdfs:comment "Animals fail to decrease their locomotion rate in response the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000024 , obo:WBPhenotype_0001626 .
obo:CHEBI_26835 a rdfs:Class ;
rdfs:label "sulfur molecular entity" ;
rdfs:subClassOf obo:CHEBI_33304 .
obo:WBPhenotype_0002568 a rdfs:Class ;
rdfs:label "long-term associative memory phenotype"@en ;
rdfs:comment "Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s)." ;
rdfs:subClassOf obo:WBPhenotype_0002564 .
obo:GO_0061066 a rdfs:Class ;
rdfs:label "positive regulation of dauer larval development" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ;
rdfs:subClassOf obo:GO_0061063 , obo:GO_0061065 , obo:GO_0065007 .
obo:WBPhenotype_0001498 a rdfs:Class ;
rdfs:label "sperm pseudopod physiology variant" ;
rdfs:comment "Animals exhibit variations in any physical or chemical process required for the pseudopod of the sperm to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000987 , obo:WBPhenotype_0002551 .
obo:PATO_0001555 a rdfs:Class ;
rdfs:label "has number of" ;
rdfs:comment "The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts." ;
rdfs:subClassOf obo:PATO_0000070 .
obo:CHEBI_37581 a rdfs:Class ;
rdfs:label "gamma-lactone" ;
rdfs:comment "A lactone having a five-membered lactone ring." ;
rdfs:subClassOf obo:CHEBI_25000 .
obo:WBbt_0005837 a rdfs:Class ;
rdfs:label "chemosensory neuron" ;
rdfs:comment "neuron that senses soluable chemicals" ;
rdfs:subClassOf obo:WBbt_0005759 .
obo:GO_1902903 a rdfs:Class ;
rdfs:label "regulation of supramolecular fiber organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:PATO_0002001 a rdfs:Class ;
rdfs:label "has fewer parts of type" ;
rdfs:comment "The bearer of this quality has_part < n AND has_part > 0 of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly." ;
rdfs:subClassOf obo:PATO_0001997 , obo:PATO_0001999 , obo:PATO_0002303 .
obo:CHEBI_36338 a rdfs:Class ;
rdfs:label "lepton" ;
rdfs:comment "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek λεπτοσ (small, thin)." ;
rdfs:subClassOf obo:CHEBI_33233 , obo:CHEBI_36340 .
obo:WBPhenotype_0001509 a rdfs:Class ;
rdfs:label "rays missing" ;
rdfs:comment "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are absent." ;
rdfs:subClassOf obo:WBPhenotype_0000199 , obo:WBPhenotype_0000505 , obo:WBPhenotype_0002174 .
obo:WBPhenotype_0000133 a rdfs:Class ;
rdfs:label "expression lipogenic enzyme reduced" ;
rdfs:comment "The levels of an enzyme involved in the manufacture of lipids are decreased compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000123 .
obo:CHEBI_35186 a rdfs:Class ;
rdfs:label "terpene" ;
rdfs:comment "A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]." ;
rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_24913 .
obo:CHEBI_23116 a rdfs:Class ;
rdfs:label "chlorine atom" ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_24473 .
obo:WBPhenotype_0000476 a rdfs:Class ;
rdfs:label "progressive muscle detachment" ;
rdfs:comment "The connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues diminishes over time." ;
rdfs:subClassOf obo:WBPhenotype_0000475 .
obo:GO_0007112 a rdfs:Class ;
rdfs:label "male meiosis cytokinesis" ;
rdfs:comment "A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells." ;
rdfs:subClassOf obo:GO_0000910 , obo:GO_0033206 .
obo:GO_0071470 a rdfs:Class ;
rdfs:label "cellular response to osmotic stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ;
rdfs:subClassOf obo:GO_0006970 , obo:GO_0062197 , obo:GO_0071214 .
obo:WBPhenotype_0002514 a rdfs:Class ;
rdfs:label "backing absent"@en ;
rdfs:comment "Animals do not exhibit backward locomotion under conditions that induce backward locomotion in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001005 .
obo:WBPhenotype_0000436 a rdfs:Class ;
rdfs:label "protein subcellular localization variant" ;
rdfs:comment "Any variation in the placement of a protein within in a cell or cellular compartment compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001408 .
obo:GO_0016241 a rdfs:Class ;
rdfs:label "regulation of macroautophagy" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of macroautophagy." ;
rdfs:subClassOf obo:GO_0010506 , obo:GO_0065007 .
obo:WBPhenotype_0000155 a rdfs:Class ;
rdfs:label "cell polarity reversed" ;
rdfs:comment "Contents or structures of the cell are oriented on the opposite side of the cell compared to control animals; In C. elegans, this can result in the fate pattern of descendants being flipped." ;
rdfs:subClassOf obo:WBPhenotype_0000104 .
obo:CHEBI_25728 a rdfs:Class ;
rdfs:label "osmolyte" ;
rdfs:comment "A solute used by a cell under water stress to maintain cell volume." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_23019 a rdfs:Class ;
rdfs:label "carbonyl group" ;
rdfs:subClassOf obo:CHEBI_51422 .
obo:WBPhenotype_0001949 a rdfs:Class ;
rdfs:label "diakinesis region organization variant" ;
rdfs:comment "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diakinesis stage. In C. elegans the diakinesis region occurs in the proximal gonad arm and is preceded by the diplotene region. In the diakinesis region oocytes arrest until oocyte maturation occurs." ;
rdfs:subClassOf obo:WBPhenotype_0001355 , obo:WBPhenotype_0001948 .
obo:WBPhenotype_0001193 a rdfs:Class ;
rdfs:label "disorganized pharyngeal EPG" ;
rdfs:comment "Electropharyngeograms do not show a similar pattern as control animals. C. elegans animals show a repeating regular pattern in which each pump is associated with an excitatory depolarizing wave, often punctuated by brief negative spikes, followed by a plateau phase, and ending with an inhibitory hyperpolarizing wave." ;
rdfs:subClassOf obo:WBPhenotype_0000980 .
obo:WBPhenotype_0002001 a rdfs:Class ;
rdfs:label "synapse density variant" ;
rdfs:comment "The number of synapses per unit area of a neuron differs in the animal compared to that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000604 .
obo:WBPhenotype_0001589 a rdfs:Class ;
rdfs:label "microtubule nucleation variant" ;
rdfs:comment "Any variation that alters the characteristic de novo formation of a microtubule compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001588 .
obo:WBls_0000825 a rdfs:Class ;
rdfs:label "C. elegans life stage"@en ;
rdfs:comment "A life stage of the nematode Caenorhabditis elegans" ;
rdfs:subClassOf obo:WBls_0000001 .
obo:CHEBI_51086 a rdfs:Class ;
rdfs:label "chemical role" ;
rdfs:comment "A role played by the molecular entity or part thereof within a chemical context." ;
rdfs:subClassOf obo:CHEBI_50906 .
obo:CHEBI_26078 a rdfs:Class ;
rdfs:label "phosphoric acid" ;
rdfs:comment "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." ;
rdfs:subClassOf obo:CHEBI_59698 .
obo:WBPhenotype_0001461 a rdfs:Class ;
rdfs:label "sodium acetate chemotaxis variant" ;
rdfs:comment "Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium acetate. In C. elegans, at specific concentrations, sodium acetate is an attractant. Sodium acetate has also been used to assay for Na+ attraction." ;
rdfs:subClassOf obo:WBPhenotype_0001047 .
obo:GO_0048635 a rdfs:Class ;
rdfs:label "negative regulation of muscle organ development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." ;
rdfs:subClassOf obo:GO_0048634 , obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 .
obo:PATO_0002318 a rdfs:Class ;
rdfs:label "superelliptic" ;
rdfs:comment "A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt" ;
rdfs:subClassOf obo:PATO_0002006 .
obo:CHEBI_59138 a rdfs:Class ;
rdfs:label "(8S)-cinchonan" ;
rdfs:comment "The (8S)-epimer of cinchonan." ;
rdfs:subClassOf obo:CHEBI_59137 .
obo:WBPhenotype_0001782 a rdfs:Class ;
rdfs:label "anoxia response attenuated" ;
rdfs:comment "Response to trace levels of oxygen is reduced or weakened compared to the response of control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002424 .
obo:GO_0006397 a rdfs:Class ;
rdfs:label "mRNA processing" ;
rdfs:comment "Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide." ;
rdfs:subClassOf obo:GO_0006396 , obo:GO_0016071 .
obo:WBPhenotype_0000955 a rdfs:Class ;
rdfs:label "lateral ganglia development variant" ;
rdfs:comment "Any variation in the progression of the left and right lateral ganglia which lie beside the nerve ring in the head over time from its initial formation to its mature form compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000943 .
obo:GO_0007612 a rdfs:Class ;
rdfs:label "learning" ;
rdfs:comment "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience." ;
rdfs:subClassOf obo:GO_0007611 .
obo:WBPhenotype_0001871 a rdfs:Class ;
rdfs:label "drug induced life span variant" ;
rdfs:comment "Life span of the animal is not influenced by drug exposure in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000039 , obo:WBPhenotype_0000631 .
obo:GO_0042420 a rdfs:Class ;
rdfs:label "dopamine catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ;
rdfs:subClassOf obo:GO_0042417 , obo:GO_0042424 .
obo:CHEBI_35605 a rdfs:Class ;
rdfs:label "carbon oxoacid" ;
rdfs:subClassOf obo:CHEBI_24833 , obo:CHEBI_36963 .
obo:WBPhenotype_0002168 a rdfs:Class ;
rdfs:label "transgenerational loss of fertility" ;
rdfs:comment "Animals exhibit a decline in fertility over generations. This is often assessed by counting laid eggs over successive generations." ;
rdfs:subClassOf obo:WBPhenotype_0000145 .
obo:WBPhenotype_0002472 a rdfs:Class ;
rdfs:label "cilia length decreased" ;
rdfs:comment "Animals exhibit a reduction in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002470 .
obo:CHEBI_32449 a rdfs:Class ;
rdfs:label "D-cysteinate(1-)" ;
rdfs:comment "The D-enantiomer of cysteinate(1−)." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_32456 .
obo:CHEBI_49200 a rdfs:Class ;
rdfs:label "EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor" ;
rdfs:comment "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H+/K+-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors." ;
rdfs:subClassOf obo:CHEBI_76895 .
obo:WBPhenotype_0001360 a rdfs:Class ;
rdfs:label "hermaphrodite self sterile" ;
rdfs:comment "Hermaphrodites fail to produce any viable progeny via self-fertilization. However, such hermaphrodites can successfully reproduce if mated to control males." ;
rdfs:subClassOf obo:WBPhenotype_0000694 .
obo:WBPhenotype_0001246 a rdfs:Class ;
rdfs:label "no transport distal segment cilia" ;
rdfs:comment "The bidirectional transport of molecules along the distal segment of axonemal microtubules of the cilia is absent." ;
rdfs:subClassOf obo:WBPhenotype_0001243 .
obo:PATO_0001708 a rdfs:Class ;
rdfs:label "1-D extent" ;
rdfs:comment "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension." ;
rdfs:subClassOf obo:PATO_0000117 .
obo:WBPhenotype_0000284 a rdfs:Class ;
rdfs:label "sperm transfer defective" ;
rdfs:comment "Any defect in the process whereby a male inseminates his partner by introducing sperm into the genital tract." ;
rdfs:subClassOf obo:WBPhenotype_0001414 , obo:WBPhenotype_0004006 .
obo:CHEBI_25491 a rdfs:Class ;
rdfs:label "nematicide" ;
rdfs:comment "A substance used to destroy pests of the phylum Nematoda (roundworms)." ;
rdfs:subClassOf obo:CHEBI_25944 .
obo:WBPhenotype_0002395 a rdfs:Class ;
rdfs:label "corpse engulfment initiation variant" ;
rdfs:comment "Animals exhibit variations in recognition of cell corpses and initiation of corpse engulfment, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000243 .
obo:PATO_0000573 a rdfs:Class ;
rdfs:label "increased length" ;
rdfs:comment "A length quality which is relatively large." ;
rdfs:subClassOf obo:PATO_0000122 , obo:PATO_0000586 .
obo:GO_0005829 a rdfs:Class ;
rdfs:label "cytosol" ;
rdfs:comment "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0000959 a rdfs:Class ;
rdfs:label "mitochondrial RNA metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ;
rdfs:subClassOf obo:GO_0016070 .
obo:GO_0051328 a rdfs:Class ;
rdfs:label "meiotic interphase" ;
rdfs:comment "The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA." ;
rdfs:subClassOf obo:GO_0051325 , obo:GO_0098762 .
obo:WBPhenotype_0000819 a rdfs:Class ;
rdfs:label "postembryonic behavior variant" ;
rdfs:comment "Behavior characteristic of postembryonic stage(s) is altered compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001000 .
obo:WBPhenotype_0000251 a rdfs:Class ;
rdfs:label "octopamine deficient" ;
rdfs:comment "Animals do not contain or are unable to maintain a perceivable level of octopamine capable of initiating or maintaining dopamine-dependent cell activity." ;
rdfs:subClassOf obo:WBPhenotype_0000250 .
obo:GO_0006259 a rdfs:Class ;
rdfs:label "DNA metabolic process" ;
rdfs:comment "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides." ;
rdfs:subClassOf obo:GO_0090304 .
obo:GO_0070482 a rdfs:Class ;
rdfs:label "response to oxygen levels" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." ;
rdfs:subClassOf obo:GO_0009628 .
obo:WBPhenotype_0002307 a rdfs:Class ;
rdfs:label "tail movement increased" ;
rdfs:comment "Animals exhibit an increase in the movement of the most posterior portion of the body to a new location compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000597 , obo:WBPhenotype_0002287 .
obo:WBPhenotype_0001617 a rdfs:Class ;
rdfs:label "ethosuximide resistant" ;
rdfs:comment "Animals fail to respond to the concentration of ethosuximide, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001615 .
obo:WBPhenotype_0002591 a rdfs:Class ;
rdfs:label "dendrite length reduced"@en ;
rdfs:comment "One or more neurons of the animal exhibit one or more dendrites with reduced length compared to the corresponding dendrites in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000882 , obo:WBPhenotype_0002647 .
obo:WBPhenotype_0000758 a rdfs:Class ;
rdfs:label "L4 adult molt defect" ;
rdfs:comment "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L4 to adult transition." ;
rdfs:subClassOf obo:WBPhenotype_0000638 .
obo:WBbt_0004522 a rdfs:Class ;
rdfs:label "anchor cell" ;
rdfs:comment "anchor cell, induces vulva, part of hermaphrodite gonad." ;
rdfs:subClassOf obo:WBbt_0007815 .
obo:WBPhenotype_0001928 a rdfs:Class ;
rdfs:label "extra gonad arms" ;
rdfs:comment "Animals produce an excess number of gonad arms compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000399 .
obo:CHEBI_48975 a rdfs:Class ;
rdfs:label "substituted aniline" ;
rdfs:subClassOf obo:CHEBI_22562 .
obo:WBbt_0004540 a rdfs:Class ;
rdfs:label "excretory duct cell" ;
rdfs:comment "cell that forms the duct of the excretory system." ;
rdfs:subClassOf obo:WBbt_0005754 .
obo:WBPhenotype_0000245 a rdfs:Class ;
rdfs:label "SM migration variant" ;
rdfs:comment "Variations in the movement of sex myoblasts compared to control animals. In C. elegans, the larval SM migrate anteriorly to the precise center of the developing hermaphrodite gonad." ;
rdfs:subClassOf obo:WBPhenotype_0001230 .
obo:GO_0043228 a rdfs:Class ;
rdfs:label "membraneless organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." ;
rdfs:subClassOf obo:GO_0043226 .
obo:CHEBI_25348 a rdfs:Class ;
rdfs:label "methylxanthine" ;
rdfs:subClassOf obo:CHEBI_26385 .
obo:CHEBI_51447 a rdfs:Class ;
rdfs:label "organic univalent group" ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:GO_2001229 a rdfs:Class ;
rdfs:label "negative regulation of response to gamma radiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation." ;
rdfs:subClassOf obo:GO_0048585 , obo:GO_0065007 , obo:GO_2001228 .
obo:GO_2000279 a rdfs:Class ;
rdfs:label "negative regulation of DNA biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010558 , obo:GO_0051053 , obo:GO_0065007 , obo:GO_2000278 .
obo:WBPhenotype_0001477 a rdfs:Class ;
rdfs:label "anterograde transport variant" ;
rdfs:comment "Any variation in the directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002563 .
obo:WBbt_0003733 a rdfs:Class ;
rdfs:label "corpus" ;
rdfs:comment "the first, anterior bulb of the pharynx." ;
rdfs:subClassOf obo:WBbt_0005789 .
obo:WBPhenotype_0002243 a rdfs:Class ;
rdfs:label "phytochelatin synthesis deficient" ;
rdfs:comment "Animals do not produce the same amount of functional phytochelatins as measured in control worms. Phytochelatins are any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes." ;
rdfs:subClassOf obo:WBPhenotype_0001696 .
obo:CHEBI_43474 a rdfs:Class ;
rdfs:label "hydrogenphosphate" ;
rdfs:comment "A phosphate ion that is the conjugate base of dihydrogenphosphate." ;
rdfs:subClassOf obo:CHEBI_35780 , obo:CHEBI_79388 .
obo:WBPhenotype_0000944 a rdfs:Class ;
rdfs:label "neurite development variant" ;
rdfs:comment "Variations in the progression of a neuronal extension (such as axons or dendrites) over time, from its formation to the mature structure compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000816 .
obo:WBPhenotype_0000685 a rdfs:Class ;
rdfs:label "larval growth slow" ;
rdfs:comment "Any variation that causes a reduction in growth rate during larval stages compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000438 , obo:WBPhenotype_0000676 , obo:WBPhenotype_0001016 .
obo:WBPhenotype_0000442 a rdfs:Class ;
rdfs:label "larval development retarded" ;
rdfs:comment "The developmental progression of a larva over time, from its formation to its mature structure is delayed compared to control. The larva is the early, immature form of an animal between hatching and adulthood." ;
rdfs:subClassOf obo:WBPhenotype_0000750 , obo:WBPhenotype_0000848 .
obo:CHEBI_33671 a rdfs:Class ;
rdfs:label "heteropolycyclic compound" ;
rdfs:comment "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." ;
rdfs:subClassOf obo:CHEBI_33635 , obo:CHEBI_5686 .
obo:CHEBI_23495 a rdfs:Class ;
rdfs:label "cyclopentanols" ;
rdfs:comment "An alcohol in which one or more hydroxy groups are attached to a cyclopentane skeleton." ;
rdfs:subClassOf obo:CHEBI_23493 , obo:CHEBI_30879 .
obo:WBPhenotype_0000425 a rdfs:Class ;
rdfs:label "antibody staining reduced" ;
rdfs:comment "Any variation that results in a decrease in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000424 .
obo:GO_1904513 a rdfs:Class ;
rdfs:label "negative regulation of initiation of premeiotic DNA replication" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication." ;
rdfs:subClassOf obo:GO_0032297 , obo:GO_0051447 , obo:GO_0065007 , obo:GO_1902576 , obo:GO_1904512 .
obo:WBPhenotype_0000482 a rdfs:Class ;
rdfs:label "garlic chemotaxis defective" ;
rdfs:comment "Failure to execute the characteristic response to garlic as defined by control animals. In C. elegans, garlic is typically a repellent." ;
rdfs:subClassOf obo:WBPhenotype_0001449 , obo:WBPhenotype_0001451 .
obo:WBPhenotype_0001938 a rdfs:Class ;
rdfs:label "DNA repair variant" ;
rdfs:comment "Any variation in the process of restoring DNA after damage. DNA damage can be caused by a many chemical or physical agents, and this damage is repaired by a variety of different DNA repair pathways." ;
rdfs:subClassOf obo:WBPhenotype_0000732 .
obo:GO_1902975 a rdfs:Class ;
rdfs:label "mitotic DNA replication initiation" ;
rdfs:comment "Any DNA replication initiation involved in mitotic cell cycle DNA replication." ;
rdfs:subClassOf obo:GO_1902315 , obo:GO_1903047 .
obo:WBPhenotype_0000267 a rdfs:Class ;
rdfs:label "cell cleavage delayed" ;
rdfs:comment "Any variation that causes a delay in the stereotypical cleavage event compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000266 , obo:WBPhenotype_0000438 .
obo:PATO_0000965 a rdfs:Class ;
rdfs:label "symmetry" ;
rdfs:comment "A pattern quality of inhering in a bearer by virtue of the correspondence in size, shape, and relative position of the bearer's parts on opposite sides of a dividing line or median plane or about a center or axis." ;
rdfs:subClassOf obo:PATO_0000060 .
obo:CHEBI_63534 a rdfs:Class ;
rdfs:label "monoamine" ;
rdfs:comment "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." ;
rdfs:subClassOf obo:CHEBI_64365 .
obo:WBPhenotype_0000825 a rdfs:Class ;
rdfs:label "postembryonic cell lineage variant" ;
rdfs:comment "The descendants of a postembryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000093 .
obo:CHEBI_50356 a rdfs:Class ;
rdfs:label "organic iodide salt" ;
rdfs:subClassOf obo:CHEBI_24858 , obo:CHEBI_51069 .
obo:GO_0043039 a rdfs:Class ;
rdfs:label "tRNA aminoacylation" ;
rdfs:comment "The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules." ;
rdfs:subClassOf obo:GO_0006399 , obo:GO_0043038 .
obo:WBPhenotype_0002194 a rdfs:Class ;
rdfs:label "food dependent body size variant" ;
rdfs:comment "Animals do not differ in size when grown on different food sources to the same extent as that measured for control animals. For example, in C. elegans, wild type worms are 1.65 times larger when grown on HB101 compared to those grown on OP50." ;
rdfs:subClassOf obo:WBPhenotype_0002195 .
obo:WBPhenotype_0001379 a rdfs:Class ;
rdfs:label "organism toxic chemical response variant" ;
rdfs:comment "Animals exhibit variations in their response to a specific toxic chemical compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000523 .
obo:WBPhenotype_0001860 a rdfs:Class ;
rdfs:label "endocytic recycling defective" ;
rdfs:comment "Variations in the directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001422 .
obo:CHEBI_48544 a rdfs:Class ;
rdfs:label "methanesulfonates" ;
rdfs:comment "Esters or salts of methanesulfonic acid." ;
rdfs:subClassOf obo:CHEBI_33261 .
obo:GO_0048087 a rdfs:Class ;
rdfs:label "positive regulation of developmental pigmentation" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ;
rdfs:subClassOf obo:GO_0048070 , obo:GO_0048518 , obo:GO_0065007 .
obo:WBPhenotype_0002220 a rdfs:Class ;
rdfs:label "antimonite hypersensitivity" ;
rdfs:comment "Animals respond to antimonite at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002217 .
obo:WBPhenotype_0001636 a rdfs:Class ;
rdfs:label "excess intestinal cells" ;
rdfs:comment "Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage." ;
rdfs:subClassOf obo:WBPhenotype_0000708 , obo:WBPhenotype_0002175 , obo:WBPhenotype_0002552 .
obo:WBPhenotype_0002369 a rdfs:Class ;
rdfs:label "sister cell division timing asynchrony reduced" ;
rdfs:comment "Animals exhibit sister cells that have lost otherwise normal asynchrony of cell division timing, compared to control animals. This results in sister cells aberrantly dividing in synchrony." ;
rdfs:subClassOf obo:WBPhenotype_0000746 .
obo:PATO_0000165 a rdfs:Class ;
rdfs:label "time" ;
rdfs:comment "A quality in which events occur in sequence." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:IAO_0000027 a rdfs:Class ;
rdfs:label "data entity"@en ;
rdfs:comment "An information content entity that is intended to be one or more truthful statement(s) about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:WBPhenotype_0002179 a rdfs:Class ;
rdfs:label "X ray induced mitotic germ cell arrest defective" ;
rdfs:comment "Animals do not arrest mitotic germ cell division, as control animals, when treated with X-ray radiation." ;
rdfs:subClassOf obo:WBPhenotype_0001324 .
obo:WBPhenotype_0002409 a rdfs:Class ;
rdfs:label "extra cleavage furrow" ;
rdfs:comment "One or more extra cleavage furrows are observed in a cell about to undergo division." ;
rdfs:subClassOf obo:WBPhenotype_0002410 .
obo:GO_0007286 a rdfs:Class ;
rdfs:label "spermatid development" ;
rdfs:comment "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0007281 .
obo:WBPhenotype_0000498 a rdfs:Class ;
rdfs:label "methyl methanesulfonate response variant" ;
rdfs:comment "Animals exhibit variations in their response to methyl methanesulfonate compared to that observed in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000067 .
obo:WBPhenotype_0001189 a rdfs:Class ;
rdfs:label "adherens junctions variant pharyngeal muscle" ;
rdfs:comment "Any variation in the cell junctions of the pharyngeal muscle at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001046 , obo:WBPhenotype_0001745 .
obo:WBPhenotype_0001206 a rdfs:Class ;
rdfs:label "movement variant" ;
rdfs:comment "Variations in the process by which an organism travels from one location to another compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:GO_1903328 a rdfs:Class ;
rdfs:label "positive regulation of tRNA metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of tRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051254 , obo:GO_0065007 , obo:GO_1903326 .
obo:WBPhenotype_0001711 a rdfs:Class ;
rdfs:label "rhythmic behavior variant" ;
rdfs:comment "Animals exhibit variations in actions or responses that occur with measurable periodicity, from that observed for control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000525 .
obo:CHEBI_24527 a rdfs:Class ;
rdfs:label "herbicide" ;
rdfs:comment "A substance used to destroy plant pests." ;
rdfs:subClassOf obo:CHEBI_25944 .
obo:GO_0060107 a rdfs:Class ;
rdfs:label "annuli extracellular matrix" ;
rdfs:comment "The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present." ;
rdfs:subClassOf obo:GO_0110165 .
obo:WBPhenotype_0000172 a rdfs:Class ;
rdfs:label "cell proliferation increased" ;
rdfs:comment "The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are increased." ;
rdfs:subClassOf obo:WBPhenotype_0000171 .
obo:GO_0010468 a rdfs:Class ;
rdfs:label "regulation of gene expression" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ;
rdfs:subClassOf obo:GO_0010556 , obo:GO_0065007 .
obo:WBPhenotype_0000646 a rdfs:Class ;
rdfs:label "sluggish" ;
rdfs:comment "Animals move more slowly compared with control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001213 .
obo:CHEBI_64047 a rdfs:Class ;
rdfs:label "food additive" ;
rdfs:comment "Any substance which is added to food to preserve or enhance its flavour and/or appearance." ;
rdfs:subClassOf obo:CHEBI_747325 , obo:CHEBI_78295 .
obo:GO_0051261 a rdfs:Class ;
rdfs:label "protein depolymerization" ;
rdfs:comment "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." ;
rdfs:subClassOf obo:GO_0032984 .
obo:GO_0033241 a rdfs:Class ;
rdfs:label "regulation of amine catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0033238 , obo:GO_0065007 .
obo:CHEBI_32443 a rdfs:Class ;
rdfs:label "L-cysteinate(2-)" ;
rdfs:comment "The L-enantiomer of cysteinate(2−)." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_32457 .
obo:WBPhenotype_0002217 a rdfs:Class ;
rdfs:label "antimony hypersensitive" ;
rdfs:comment "Animals respond to antimony at a lower concentration or a shorter exposure compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001918 .
obo:GO_0032101 a rdfs:Class ;
rdfs:label "regulation of response to external stimulus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a response to an external stimulus." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 .
obo:WBPhenotype_0002452 a rdfs:Class ;
rdfs:label "reduced burst pharyngeal pumping response to light" ;
rdfs:comment "Animals exhibit a reduced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a lesser extent than in controls." ;
rdfs:subClassOf obo:WBPhenotype_0002450 .
obo:WBPhenotype_0000330 a rdfs:Class ;
rdfs:label "pharyngeal relaxation defective" ;
rdfs:comment "Defects in rhythmic pharyngeal relaxations compared to control animals. In C. elegans pharyngeal relaxation follows a contraction event and facilitates bacterial trapping within the pharynx while expelling liquid." ;
rdfs:subClassOf obo:WBPhenotype_0001004 .
obo:CHEBI_64909 a rdfs:Class ;
rdfs:label "poison" ;
rdfs:comment "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:WBPhenotype_0002161 a rdfs:Class ;
rdfs:label "mitotic chromatin remodeling variant" ;
rdfs:comment "Animals exhibit variations from controls in the organization of chromatin, including in relation to associated complexes, that occur during the mitotic cell division cycle." ;
rdfs:subClassOf obo:WBPhenotype_0001348 , obo:WBPhenotype_0001743 .
obo:WBPhenotype_0000418 a rdfs:Class ;
rdfs:label "intestinal cell division failure" ;
rdfs:comment "The physical partitioning and separation of an intestinal cell into daughter cells is abolished." ;
rdfs:subClassOf obo:WBPhenotype_0000417 .
obo:GO_1905881 a rdfs:Class ;
rdfs:label "positive regulation of oogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of oogenesis." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1905879 , obo:GO_2000243 .
obo:WBPhenotype_0000691 a rdfs:Class ;
rdfs:label "gonad development variant" ;
rdfs:comment "Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000624 .
obo:WBls_0000016 a rdfs:Class ;
rdfs:label "bean embryo Ce" ;
rdfs:comment "The C. elegans life stage spanning 350-390min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. Emrbyo elongation started but have not formed comma shape yet. The shape of embryo looks like a lima bean. A stage right before comma embryo. Also called lima embryo or lima bean stage." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000809 .
obo:GO_0001677 a rdfs:Class ;
rdfs:label "formation of translation initiation ternary complex" ;
rdfs:comment "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." ;
rdfs:subClassOf obo:GO_0022618 .
obo:WBPhenotype_0000458 a rdfs:Class ;
rdfs:label "starvation resistant" ;
rdfs:comment "Animals show enhanced tolerance to deprivation of nourishment, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000147 .
obo:WBbt_0005208 a rdfs:Class ;
rdfs:label "E lineage cell" ;
rdfs:comment "A cell that is the E blast cell or is a lineal descendant of E." ;
rdfs:subClassOf obo:WBbt_0004017 .
obo:WBbt_0005800 a rdfs:Class ;
rdfs:label "rectal epithelium" ;
rdfs:comment "epithelium connecting intestine and anus." ;
rdfs:subClassOf obo:WBbt_0005733 .
obo:GO_0016746 a rdfs:Class ;
rdfs:label "acyltransferase activity" ;
rdfs:comment "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor)." ;
rdfs:subClassOf obo:GO_0016740 .
obo:WBPhenotype_0000971 a rdfs:Class ;
rdfs:label "anterior pigmentation variant" ;
rdfs:comment "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the anterior body axis compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000786 .
obo:GO_0060284 a rdfs:Class ;
rdfs:label "regulation of cell development" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:WBPhenotype_0001393 a rdfs:Class ;
rdfs:label "cell acidification variant" ;
rdfs:comment "Variations in the processes that reduce the internal pH of a cell (measured by the concentration of the hydrogen ion), compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000585 .
obo:WBPhenotype_0001108 a rdfs:Class ;
rdfs:label "P0 spindle rotation failure early emb" ;
rdfs:comment "P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001107 .
obo:CHEBI_36360 a rdfs:Class ;
rdfs:label "phosphorus oxoacids and derivatives" ;
rdfs:subClassOf obo:CHEBI_26082 .
obo:GO_0036379 a rdfs:Class ;
rdfs:label "myofilament" ;
rdfs:comment "Any of the smallest contractile units of a myofibril (striated muscle fiber)." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_52837 a rdfs:Class ;
rdfs:label "quinolinium ion" ;
rdfs:subClassOf obo:CHEBI_25697 .
obo:GO_0002831 a rdfs:Class ;
rdfs:label "regulation of response to biotic stimulus" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 .
obo:GO_0006066 a rdfs:Class ;
rdfs:label "alcohol metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." ;
rdfs:subClassOf obo:GO_0044281 .
obo:WBbt_0003825 a rdfs:Class ;
rdfs:label "B cell" ;
rdfs:comment "Rectal cell, postembryonic blast cell in male" ;
rdfs:subClassOf obo:WBbt_0006783 , obo:WBbt_0008182 .
obo:GO_2000145 a rdfs:Class ;
rdfs:label "regulation of cell motility" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell motility." ;
rdfs:subClassOf obo:GO_0040012 , obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0001319 a rdfs:Class ;
rdfs:label "endogenous synaptic event frequency reduced" ;
rdfs:comment "The rate (frequency) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is decreased compared to control. Changes in frequency are indicative of presynaptic modifications." ;
rdfs:subClassOf obo:WBPhenotype_0001318 .
obo:WBbt_0003673 a rdfs:Class ;
rdfs:label "marginal cell" ;
rdfs:comment "a type of pharyngeal cell that connects basement membrane to the apices of triangle-shaped pharyngeal lumen." ;
rdfs:subClassOf obo:WBbt_0005460 , obo:WBbt_0005754 .
obo:WBPhenotype_0000605 a rdfs:Class ;
rdfs:label "reproductive system morphology variant" ;
rdfs:comment "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." ;
rdfs:subClassOf obo:WBPhenotype_0000534 .
obo:WBPhenotype_0002231 a rdfs:Class ;
rdfs:label "manganese induced oxidative stress response" ;
rdfs:comment "Oxidative stress induced by manganese differs from that of control worms." ;
rdfs:subClassOf obo:WBPhenotype_0001620 .
obo:PATO_0000440 a rdfs:Class ;
rdfs:label "regular spatial pattern" ;
rdfs:comment "A pattern quality inhering in a bearer by virtue of the bearer's having a repeatable or predictable placement." ;
rdfs:subClassOf obo:PATO_0000060 .
obo:WBPhenotype_0002579 a rdfs:Class ;
rdfs:label "basement membrane type IV collagen level phenotype"@en ;
rdfs:comment "Animals exhibit variations in the amount of type IV collagen in basement membranes, compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0002577 .
obo:GO_0050773 a rdfs:Class ;
rdfs:label "regulation of dendrite development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dendrite development." ;
rdfs:subClassOf obo:GO_0010975 , obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0044778 a rdfs:Class ;
rdfs:label "meiotic DNA integrity checkpoint signaling" ;
rdfs:comment "A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction." ;
rdfs:subClassOf obo:GO_0031570 , obo:GO_0033313 .
obo:GO_0005770 a rdfs:Class ;
rdfs:label "late endosome" ;
rdfs:comment "A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center." ;
rdfs:subClassOf obo:GO_0005768 .
obo:GO_0009269 a rdfs:Class ;
rdfs:label "response to desiccation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water." ;
rdfs:subClassOf obo:GO_0009414 .
obo:WBPhenotype_0001837 a rdfs:Class ;
rdfs:label "diet induced life span variant" ;
rdfs:comment "Life span of the animal is not influenced by changes in diet in the same manner as control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000039 , obo:WBPhenotype_0002525 .
obo:GO_0001666 a rdfs:Class ;
rdfs:label "response to hypoxia" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0036293 .
obo:GO_0051589 a rdfs:Class ;
rdfs:label "negative regulation of neurotransmitter transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051051 , obo:GO_0051588 , obo:GO_0065007 .
obo:GO_0030104 a rdfs:Class ;
rdfs:label "obsolete water homeostasis" ;
rdfs:comment "OBSOLETE. Any process involved in the maintenance of an internal steady state of water within an organism or cell." .
obo:CHEBI_33676 a rdfs:Class ;
rdfs:label "d-block molecular entity" ;
rdfs:comment "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element." ;
rdfs:subClassOf obo:CHEBI_33497 .
obo:GO_0042436 a rdfs:Class ;
rdfs:label "indole-containing compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0042430 .
obo:WBPhenotype_0001580 a rdfs:Class ;
rdfs:label "nuclear envelope breakdown variant" ;
rdfs:comment "Any variation in the progression of the controlled breakdown of the nuclear envelope, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000519 , obo:WBPhenotype_0002037 .
obo:GO_0010646 a rdfs:Class ;
rdfs:label "regulation of cell communication" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:WBPhenotype_0000657 a rdfs:Class ;
rdfs:label "neuronal synaptic transmission variant" ;
rdfs:comment "Any variation in the process of information transfer between two neurons; usually in reference to chemical synapses, but can also be used to refer to electrical synapses compared to control (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000584 .
obo:CHEBI_16526 a rdfs:Class ;
rdfs:label "carbon dioxide" ;
rdfs:comment "A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_138675 , obo:CHEBI_23014 , obo:CHEBI_64708 .
obo:GO_1905154 a rdfs:Class ;
rdfs:label "negative regulation of membrane invagination" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1905153 .
obo:WBPhenotype_0001129 a rdfs:Class ;
rdfs:label "cleavage furrow defective early emb" ;
rdfs:comment "Embryos exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ;
rdfs:subClassOf obo:WBPhenotype_0001078 , obo:WBPhenotype_0002410 .
obo:GO_0048490 a rdfs:Class ;
rdfs:label "anterograde synaptic vesicle transport" ;
rdfs:comment "The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse." ;
rdfs:subClassOf obo:GO_0008089 , obo:GO_0099517 .
obo:WBbt_0008409 a rdfs:Class ;
rdfs:label "tail precursor cell" ;
rdfs:comment "Tail lateral ectoblasts that give rise to neurons, hypodermis and glial lineages. While initially identical, after the L2 lethargus the T cell lineages become markedly different between males and hermaphrodites helping to provide the sexually dimorphic tail structures found in males." ;
rdfs:subClassOf obo:WBbt_0006783 .
obo:WBPhenotype_0000144 a rdfs:Class ;
rdfs:label "pathogen induced cell death increased" ;
rdfs:comment "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000142 , obo:WBPhenotype_0001269 .
obo:WBPhenotype_0001697 a rdfs:Class ;
rdfs:label "chondroitin biosynthesis variant" ;
rdfs:comment "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of chondroitin sulfate compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001696 .
obo:WBPhenotype_0000814 a rdfs:Class ;
rdfs:label "marginal cell development variant" ;
rdfs:comment "Any variation in the progression of a marginal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A marginal cell is a pharyngeal cell that connects the basement membrane to the apices of the triangle-shaped pharyngeal lumen." ;
rdfs:subClassOf obo:WBPhenotype_0000529 , obo:WBPhenotype_0000619 , obo:WBPhenotype_0000707 .
obo:WBPhenotype_0002101 a rdfs:Class ;
rdfs:label "endoplasmic reticulum localization variant" ;
rdfs:comment "Any variation in the subcellular localization of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that exists in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ;
rdfs:subClassOf obo:WBPhenotype_0002098 .
obo:CHEBI_48360 a rdfs:Class ;
rdfs:label "amphiprotic solvent" ;
rdfs:comment "Self-ionizing solvent possessing both characteristics of Brønsted acids and bases." ;
rdfs:subClassOf obo:CHEBI_48356 , obo:CHEBI_48359 .
obo:GO_0097435 a rdfs:Class ;
rdfs:label "supramolecular fiber organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." ;
rdfs:subClassOf obo:GO_0016043 .
obo:CHEBI_33964 a rdfs:Class ;
rdfs:label "silver molecular entity" ;
rdfs:subClassOf obo:CHEBI_33745 .
obo:WBPhenotype_0000534 a rdfs:Class ;
rdfs:label "organ system morphology variant" ;
rdfs:comment "Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that comprise a specific organ system." ;
rdfs:subClassOf obo:WBPhenotype_0000520 , obo:WBPhenotype_0002554 .
obo:GO_1902435 a rdfs:Class ;
rdfs:label "regulation of male mating behavior" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of male mating behavior." ;
rdfs:subClassOf obo:GO_0050795 , obo:GO_0065007 , obo:GO_2000241 .
obo:GO_1990497 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translation in response to stress" ;
rdfs:comment "Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0043555 , obo:GO_0065007 , obo:GO_2000765 .
obo:GO_1904000 a rdfs:Class ;
rdfs:label "positive regulation of eating behavior" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of eating behavior." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903998 , obo:GO_2000253 .
obo:WBbt_0005440 a rdfs:Class ;
rdfs:label "pharyngeal nervous system" ;
rdfs:comment "The pharyngeal nervous system is composed of 20 pharyngeal neurons which lie completely within the pharynx." ;
rdfs:subClassOf obo:WBbt_0005746 .
obo:WBbt_0005176 a rdfs:Class ;
rdfs:label "GLR" ;
rdfs:comment "set of six cells that form a thin cylindrical sheet between pharynx and ring neuropile; no chemical synapses, but gap junctions with muscle arms and RME motor neurons, might be glial cells" ;
rdfs:subClassOf obo:WBbt_0005762 .
obo:GO_0030728 a rdfs:Class ;
rdfs:label "ovulation" ;
rdfs:comment "The release of a mature ovum/oocyte from an ovary." ;
rdfs:subClassOf obo:GO_0048609 .
obo:CHEBI_50114 a rdfs:Class ;
rdfs:label "estrogen" ;
rdfs:comment "A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens." ;
rdfs:subClassOf obo:CHEBI_50112 .
obo:CHEBI_35780 a rdfs:Class ;
rdfs:label "phosphate ion" ;
rdfs:comment "A phosphorus oxoanion that is the conjugate base of phosphoric acid." ;
rdfs:subClassOf obo:BFO_0000004 , obo:CHEBI_33461 .
obo:WBPhenotype_0002206 a rdfs:Class ;
rdfs:label "galactose metabolism variant" ;
rdfs:comment "Animals process dietary galactose differently than control animals, these differences can result in increased and or decreased levels of intermediary galactose metabolites." ;
rdfs:subClassOf obo:WBPhenotype_0000027 .
obo:CHEBI_46848 a rdfs:Class ;
rdfs:label "N-arylpiperazine" ;
rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_33860 , obo:CHEBI_50996 .
obo:WBPhenotype_0001890 a rdfs:Class ;
rdfs:label "body wall muscle dense body variant" ;
rdfs:comment "Any variation in the attachment plaque for thin filaments onto the cell membrane. The dense body in body wall muscles is especially large, indenting far into the cytoplasm to border each sarcomere, thus providing a long row of coherent attachment sites at regular intervals (WormAtlas)." ;
rdfs:subClassOf obo:WBPhenotype_0001889 .
obo:WBPhenotype_0001771 a rdfs:Class ;
rdfs:label "endo siRNA production variant" ;
rdfs:comment "Animals exhibit variations in the length or amount of any endogenous small interfering RNA molecule populations compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000743 .
obo:WBPhenotype_0001603 a rdfs:Class ;
rdfs:label "cyproheptadine resistant" ;
rdfs:comment "Animals fail to respond to the concentration of cyproheptadine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0001502 , obo:WBPhenotype_0001601 .
obo:GO_0045786 a rdfs:Class ;
rdfs:label "negative regulation of cell cycle" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0051726 , obo:GO_0065007 .
obo:WBPhenotype_0001578 a rdfs:Class ;
rdfs:label "cholinergic agonist resistant" ;
rdfs:comment "Animals fail to respond to the concentration of cholinergic agonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000011 .
obo:WBPhenotype_0000465 a rdfs:Class ;
rdfs:label "high oxygen resistant" ;
rdfs:comment "Animals fail to respond to the high concentrations of oxygen that elicit a response in control animals." ;
rdfs:subClassOf obo:WBPhenotype_0000464 .
obo:GO_2000134 a rdfs:Class ;
rdfs:label "negative regulation of G1/S transition of mitotic cell cycle" ;
rdfs:comment "Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901991 , obo:GO_1902807 , obo:GO_2000045 .
obo:GO_0036495 a rdfs:Class ;
rdfs:label "negative regulation of translation initiation in response to endoplasmic reticulum stress" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress." ;
rdfs:subClassOf obo:GO_0032057 , obo:GO_0036491 , obo:GO_0065007 , obo:GO_1902010 .
obo:WBls_0000814 a rdfs:Class ;
rdfs:label "C. elegans life stage occurring during gastrulation"@en ;
rdfs:comment "A C. elegans life stage that occurs during the gastrulating embryo life stage" ;
rdfs:subClassOf obo:WBls_0000812 .
obo:GO_0030537 a rdfs:Class ;
rdfs:label "larval behavior" ;
rdfs:comment "Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics." ;
rdfs:subClassOf obo:GO_0007610 .
obo:WBPhenotype_0001450 a rdfs:Class ;
rdfs:label "aqueous negative chemotaxis variant" ;
rdfs:comment "Animals exhibit variations through directed movement, in response to repellant water soluble chemicals, compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000481 , obo:WBPhenotype_0001443 .
obo:WBPhenotype_0002018 a rdfs:Class ;
rdfs:label "retarded seam cell fusion" ;
rdfs:comment "Seam cells fuse to form a continuous syncytium along the body wall at a later stage of development compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000166 .
obo:UBERON_0000062 a rdfs:Class .
obo:WBPhenotype_0000274 a rdfs:Class ;
rdfs:label "dead eggs laid" ;
rdfs:comment "Animals lay eggs that are inviable." ;
rdfs:subClassOf obo:WBPhenotype_0000640 , obo:WBPhenotype_0000806 .
obo:GO_0050801 a rdfs:Class ;
rdfs:label "monoatomic ion homeostasis" ;
rdfs:comment "Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ;
rdfs:subClassOf obo:GO_0048878 .
obo:WBPhenotype_0000544 a rdfs:Class ;
rdfs:label "backward kinker" ;
rdfs:comment "Backward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves backward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas)." ;
rdfs:subClassOf obo:WBPhenotype_0000002 .
obo:WBPhenotype_0001112 a rdfs:Class ;
rdfs:label "aster AB resembles P1 aster early emb" ;
rdfs:comment "The morphology of the AB aster resembles that of the P1 aster in the inviable one- to four-cell embryo." ;
rdfs:subClassOf obo:WBPhenotype_0001111 .
obo:WBPhenotype_0002137 a rdfs:Class ;
rdfs:label "reduced translation initiation" ;
rdfs:comment "The rate of the process preceding formation of the peptide bond between the first two amino acids of a protein is reduced. This process includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. Increase in free ribosomes (monosomes) are indicative of reduced translation initiation." ;
rdfs:subClassOf obo:WBPhenotype_0000121 .
obo:CHEBI_24867 a rdfs:Class ;
rdfs:label "monoatomic ion" ;
rdfs:subClassOf obo:CHEBI_24870 , obo:CHEBI_33238 .
obo:GO_1901162 a rdfs:Class ;
rdfs:label "primary amino compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of primary amino compound." ;
rdfs:subClassOf obo:GO_0009058 .
obo:WBPhenotype_0001979 a rdfs:Class ;
rdfs:label "gonad vesiculated" ;
rdfs:comment "Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad." ;
rdfs:subClassOf obo:WBPhenotype_0001355 .
obo:WBPhenotype_0001427 a rdfs:Class ;
rdfs:label "cytoplasmic appearance variant" ;
rdfs:comment "Animals exhibit variations in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control animals." ;
rdfs:subClassOf obo:WBPhenotype_0010002 .
obo:GO_0019778 a rdfs:Class ;
rdfs:label "Atg12 activating enzyme activity" ;
rdfs:comment "Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond." ;
rdfs:subClassOf obo:GO_0008641 .
obo:GO_0000723 a rdfs:Class ;
rdfs:label "telomere maintenance" ;
rdfs:comment "Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences." ;
rdfs:subClassOf obo:GO_0006259 , obo:GO_0032200 .
obo:WBls_0000040 a rdfs:Class ;
rdfs:label "L4-adult molt Ce" ;
rdfs:comment "The stage when an animal shifts from L4 larva to adult. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle." ;
rdfs:subClassOf obo:BFO_0000003 , obo:WBls_0000824 .
obo:GO_0002181 a rdfs:Class ;
rdfs:label "cytoplasmic translation" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein." ;
rdfs:subClassOf obo:GO_0006412 .
obo:WBPhenotype_0002620 a rdfs:Class ;
rdfs:label "cell death decreased"@en ;
rdfs:comment "Animals exhibit decreased occurrence of cell death, compared to controls." ;
rdfs:subClassOf obo:WBPhenotype_0000729 .
obo:GO_0009314 a rdfs:Class ;
rdfs:label "response to radiation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." ;
rdfs:subClassOf obo:GO_0009628 .
obo:CHEBI_30320 a rdfs:Class ;
rdfs:label "thioacetate" ;
rdfs:subClassOf obo:CHEBI_35367 .
obo:GO_0046189 a rdfs:Class ;
rdfs:label "phenol-containing compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0018958 .
obo:WBPhenotype_0002070 a rdfs:Class ;
rdfs:label "egg laying response to muscimol variant" ;
rdfs:comment "Animals do not mimic control animals in their egg-laying response to muscimol exposure. In C. elegans, muscimol inhibits egg-laying." ;
rdfs:subClassOf obo:WBPhenotype_0001101 , obo:WBPhenotype_0002047 .
obo:GO_0051028 a rdfs:Class ;
rdfs:label "mRNA transport" ;
rdfs:comment "The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0050658 .
obo:CHEBI_38337 a rdfs:Class ;
rdfs:label "pyrimidone" ;
rdfs:comment "A pyrimidine carrying one or more oxo substituents." ;
rdfs:subClassOf obo:CHEBI_39447 .
obo:WBPhenotype_0001722 a rdfs:Class ;
rdfs:label "pathogen infected pharynx increase" ;
rdfs:comment "Animals exhibit a greater extent of pathogen invasion into the pharynx compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0001721 .
obo:WBPhenotype_0001209 a rdfs:Class ;
rdfs:label "skiddy" ;
rdfs:comment "Apparently normal sinusoidal movement, but appear to have poor traction on the agar surface of a culture plate." ;
rdfs:subClassOf obo:WBPhenotype_0001701 .
obo:WBPhenotype_0002030 a rdfs:Class ;
rdfs:label "magnesium homeostasis variant" ;
rdfs:comment "Variations in the regulation of levels, transport, and metabolism of magnesium ions within an organism compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0002029 .
obo:GO_0010927 a rdfs:Class ;
rdfs:label "cellular component assembly involved in morphogenesis" ;
rdfs:comment "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0048646 .
obo:GO_0005769 a rdfs:Class ;
rdfs:label "early endosome" ;
rdfs:comment "A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways." ;
rdfs:subClassOf obo:GO_0005768 .
obo:GO_0032886 a rdfs:Class ;
rdfs:label "regulation of microtubule-based process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:CHEBI_25248 a rdfs:Class ;
rdfs:label "methyl ester" ;
rdfs:comment "Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol." ;
rdfs:subClassOf obo:CHEBI_33308 .
obo:CHEBI_47923 a rdfs:Class ;
rdfs:label "tripeptide" ;
rdfs:comment "Any oligopeptide that consists of three amino-acid residues connected by peptide linkages." ;
rdfs:subClassOf obo:CHEBI_25676 .
obo:CHEBI_35554 a rdfs:Class ;
rdfs:label "cardiovascular drug" ;
rdfs:comment "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0051241 a rdfs:Class ;
rdfs:label "negative regulation of multicellular organismal process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0051239 , obo:GO_0065007 .
obo:WBPhenotype_0000313 a rdfs:Class ;
rdfs:label "meiotic progression during oogenesis variant" ;
rdfs:comment "Developing oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis)." ;
rdfs:subClassOf obo:WBPhenotype_0000186 .
obo:PATO_0000119 a rdfs:Class ;
rdfs:label "height" ;
rdfs:comment "A 1-D extent quality inhering in a bearer by virtue of the bearer's vertical dimension of extension." ;
rdfs:subClassOf obo:PATO_0001708 .
obo:GO_0051641 a rdfs:Class ;
rdfs:label "cellular localization" ;
rdfs:comment "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0051179 .
obo:GO_0002682 a rdfs:Class ;
rdfs:label "regulation of immune system process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of an immune system process." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:CHEBI_33304 a rdfs:Class ;
rdfs:label "chalcogen molecular entity" ;
rdfs:comment "Any p-block molecular entity containing a chalcogen." ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:GO_0032056 a rdfs:Class ;
rdfs:label "positive regulation of translation in response to stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0043555 , obo:GO_0045727 , obo:GO_0065007 .
obo:WBPhenotype_0000715 a rdfs:Class ;
rdfs:label "muscle excess" ;
rdfs:comment "Animals exhibit a greater number of embryonic muscle cells compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000622 , obo:WBPhenotype_0002175 , obo:WBPhenotype_0002552 .
obo:WBPhenotype_0000393 a rdfs:Class ;
rdfs:label "cell migration failure" ;
rdfs:comment "Characteristic movement of cells from one site to another is abolished compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000594 .
obo:WBPhenotype_0000753 a rdfs:Class ;
rdfs:label "L3 larval development variant" ;
rdfs:comment "Variations in the progression of the third larval stage compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000750 .
obo:CL_0000024 a rdfs:Class ;
rdfs:label "oogonial cell" ;
rdfs:comment "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." ;
rdfs:subClassOf obo:CL_0000021 .
obo:CHEBI_55374 a rdfs:Class ;
rdfs:label "oxazolidinone" ;
rdfs:comment "An oxazolidine containing one or more oxo groups." ;
rdfs:subClassOf obo:CHEBI_38329 .
obo:WBPhenotype_0000674 a rdfs:Class ;
rdfs:label "slow development" ;
rdfs:comment "The developmental progression of an animal, from its formation to its mature structure occurs over a longer time period compared to control." ;
rdfs:subClassOf obo:WBPhenotype_0000043 , obo:WBPhenotype_0000438 .
obo:BFO_0000067 a rdf:Property ;
rdfs:label "contains process"@en ;
rdfs:comment "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
rdfs:range .
obo:BFO_0000070 a rdf:Property ;
rdfs:range .
obo:IAO_0000115 a rdf:Property ;
rdfs:label "definition" ;
rdfs:comment "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
rdfs:range xsd:string .
obo:IAO_0000231 a rdf:Property ;
rdfs:label "has obsolescence reason"@en ;
rdfs:comment "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ;
rdfs:range xsd:string .
obo:IAO_0000700 a rdf:Property ;
rdfs:label "has ontology root term" ;
rdfs:comment "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ;
rdfs:range xsd:string .
obo:IAO_0100001 a rdf:Property ;
rdfs:label "term replaced by" ;
rdfs:comment "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
rdfs:range xsd:string .
obo:RO_0000052 a rdf:Property ;
rdfs:label "characteristic of"@en ;
rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002314 .
obo:RO_0000080 a rdf:Property ;
rdfs:label "quality of"@en ;
rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:RO_0000081 a rdf:Property ;
rdfs:label "role of"@en ;
rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:RO_0000086 a rdf:Property ;
rdfs:label "has quality"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
rdfs:range obo:BFO_0000019 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0000092 a rdf:Property ;
rdfs:label "disposition of"@en ;
rdfs:comment "inverse of has disposition" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:RO_0002013 a rdf:Property ;
rdfs:label "has regulatory component activity" ;
rdfs:comment "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 , obo:RO_0002017 .
obo:RO_0002014 a rdf:Property ;
rdfs:label "has negative regulatory component activity" ;
rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002335 , obo:RO_0002013 .
obo:RO_0002015 a rdf:Property ;
rdfs:label "has positive regulatory component activity" ;
rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002336 , obo:RO_0002013 .
obo:RO_0002017 a rdf:Property ;
rdfs:label "has component activity" ;
rdfs:comment "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002018 .
obo:RO_0002022 a rdf:Property ;
rdfs:label "directly regulated by" ;
rdfs:comment "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 .
obo:RO_0002023 a rdf:Property ;
rdfs:label "directly negatively regulated by" ;
rdfs:comment "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002022 .
obo:RO_0002024 a rdf:Property ;
rdfs:label "directly positively regulated by" ;
rdfs:comment "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002022 .
obo:RO_0002025 a rdf:Property ;
rdfs:label "has effector activity" ;
rdfs:comment "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002017 .
obo:RO_0002086 a rdf:Property ;
rdfs:label "ends after"@en ;
rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002222 .
obo:RO_0002090 a rdf:Property ;
rdfs:label "immediately precedes"@en ;
rdfs:comment "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:BFO_0000063 .
obo:RO_0002131 a rdf:Property ;
rdfs:label "overlaps"@en ;
rdfs:comment "x overlaps y if and only if there exists some z such that x has part z and z part of y" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002323 .
obo:RO_0002180 a rdf:Property ;
rdfs:label "has component"@en ;
rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:BFO_0000051 .
obo:RO_0002203 a rdf:Property ;
rdfs:label "develops into"@en ;
rdfs:comment "inverse of develops from" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002387 , obo:RO_0002388 , obo:RO_0002286 .
obo:RO_0002255 a rdf:Property ;
rdfs:label "developmentally contributes to"@en ;
rdfs:comment "inverse of has developmental contribution from" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002385 , obo:RO_0002286 .
obo:RO_0002259 a rdf:Property ;
rdfs:range xsd:string .
obo:RO_0002263 a rdf:Property ;
rdfs:label "acts upstream of" ;
rdfs:comment "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002264 .
obo:RO_0002264 a rdf:Property ;
rdfs:label "acts upstream of or within" ;
rdfs:comment "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002500 .
obo:RO_0002286 a rdf:Property ;
rdfs:label "developmentally succeeded by"@en ;
rdfs:comment "Inverse of developmentally preceded by" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002384 .
obo:RO_0002304 a rdf:Property ;
rdfs:label "causally upstream of, positive effect" ;
rdfs:comment "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004047 , obo:RO_0002411 .
obo:RO_0002305 a rdf:Property ;
rdfs:label "causally upstream of, negative effect" ;
rdfs:comment "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004046 , obo:RO_0002411 .
obo:RO_0002314 a rdf:Property ;
rdfs:label "characteristic of part of"@en ;
rdfs:comment "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002502 .
obo:RO_0002323 a rdf:Property ;
rdfs:label "mereotopologically related to"@en ;
rdfs:comment "A mereological relationship or a topological relationship" ;
rdfs:range .
obo:RO_0002324 a rdf:Property ;
rdfs:label "developmentally related to"@en ;
rdfs:comment "A relationship that holds between entities participating in some developmental process (GO:0032502)" ;
rdfs:range .
obo:RO_0002327 a rdf:Property ;
rdfs:label "enables"@en ;
rdfs:comment "c enables p iff c is capable of p and c acts to execute p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002215 .
obo:RO_0002328 a rdf:Property ;
rdfs:label "functionally related to"@en ;
rdfs:comment "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." ;
rdfs:range .
obo:RO_0002329 a rdf:Property ;
rdfs:label "part of structure that is capable of"@en ;
rdfs:comment "this relation holds between c and p when c is part of some c', and c' is capable of p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 .
obo:RO_0002331 a rdf:Property ;
rdfs:label "involved in"@en ;
rdfs:comment "c involved_in p if and only if c enables some process p', and p' is part of p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0000056 .
obo:RO_0002333 a rdf:Property ;
rdfs:label "enabled by"@en ;
rdfs:comment "inverse of enables" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000057 .
obo:RO_0002335 a rdf:Property ;
rdfs:label "negatively regulated by"@en ;
rdfs:comment "inverse of negatively regulates" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 .
obo:RO_0002336 a rdf:Property ;
rdfs:label "positively regulated by"@en ;
rdfs:comment "inverse of positively regulates" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 .
obo:RO_0002352 a rdf:Property ;
rdfs:label "input of"@en ;
rdfs:comment "inverse of has input" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .
obo:RO_0002385 a rdf:Property ;
rdfs:label "has potential to developmentally contribute to"@en ;
rdfs:comment "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002384 .
obo:RO_0002387 a rdf:Property ;
rdfs:label "has potential to develop into"@en ;
rdfs:comment "x has the potential to develop into y iff x develops into y or if x is capable of developing into y"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002384 .
obo:RO_0002388 a rdf:Property ;
rdfs:label "has potential to directly develop into"@en ;
rdfs:comment "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002387 .
obo:RO_0002404 a rdf:Property ;
rdfs:label "causally downstream of"@en ;
rdfs:comment "inverse of upstream of" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002427 , obo:BFO_0000062 .
obo:RO_0002405 a rdf:Property ;
rdfs:label "immediately causally downstream of"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002404 , obo:RO_0002087 .
obo:RO_0002407 a rdf:Property ;
rdfs:label "indirectly positively regulates"@en ;
rdfs:comment "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002213 .
obo:RO_0002409 a rdf:Property ;
rdfs:label "indirectly negatively regulates"@en ;
rdfs:comment "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002212 .
obo:RO_0002410 a rdf:Property ;
rdfs:label "causally related to"@en ;
rdfs:comment "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." ;
rdfs:range .
obo:RO_0002411 a rdf:Property ;
rdfs:label "causally upstream of"@en ;
rdfs:comment "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000063 .
obo:RO_0002412 a rdf:Property ;
rdfs:label "immediately causally upstream of"@en ;
rdfs:comment "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002411 , obo:RO_0002090 .
obo:RO_0002418 a rdf:Property ;
rdfs:label "causally upstream of or within" ;
rdfs:comment "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002501 .
obo:RO_0002427 a rdf:Property ;
rdfs:label "causally downstream of or within" ;
rdfs:comment "inverse of causally upstream of or within" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002501 .
obo:RO_0002428 a rdf:Property ;
rdfs:label "involved in regulation of" ;
rdfs:comment "c involved in regulation of p if c is involved in some p' and p' regulates some p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0002263 .
obo:RO_0002429 a rdf:Property ;
rdfs:label "involved in positive regulation of" ;
rdfs:comment "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002428 .
obo:RO_0002430 a rdf:Property ;
rdfs:label "involved in negative regulation of" ;
rdfs:comment "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002428 .
obo:RO_0002431 a rdf:Property ;
rdfs:label "involved in or involved in regulation of" ;
rdfs:comment "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0002500 , obo:RO_0002264 .
obo:RO_0002432 a rdf:Property ;
rdfs:label "is active in" ;
rdfs:comment "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0002131 .
obo:RO_0002436 a rdf:Property ;
rdfs:label "molecularly interacts with" ;
rdfs:comment "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002434 .
obo:RO_0002447 a rdf:Property ;
rdfs:label "phosphorylates" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002436 .
obo:RO_0002464 a rdf:Property ;
rdfs:label "helper property (not for use in curation)" ;
rdfs:range .
obo:RO_0002481 a rdf:Property ;
rdfs:label "is kinase activity" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002564 .
obo:RO_0002500 a rdf:Property ;
rdfs:label "causal agent in process" ;
rdfs:comment "A relationship between a material entity and a process where the material entity has some causal role that influences the process" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002595 .
obo:RO_0002502 a rdf:Property ;
rdfs:label "depends on" ;
rdfs:range .
obo:RO_0002559 a rdf:Property ;
rdfs:label "causally influenced by" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002506 .
obo:RO_0002563 a rdf:Property ;
rdfs:label "interaction relation helper property" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002464 .
obo:RO_0002564 a rdf:Property ;
rdfs:label "molecular interaction relation helper property" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002563 .
obo:RO_0002578 a rdf:Property ;
rdfs:label "directly regulates" ;
rdfs:comment "p directly regulates q iff p is immediately causally upstream of q and p regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002412 , obo:RO_0002211 .
obo:RO_0002584 a rdf:Property ;
rdfs:label "has part structure that is capable of" ;
rdfs:comment "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002595 , obo:RO_0002328 .
obo:RO_0002596 a rdf:Property ;
rdfs:label "capable of regulating" ;
rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a regulates p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002500 .
obo:RO_0002597 a rdf:Property ;
rdfs:label "capable of negatively regulating" ;
rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002596 .
obo:RO_0002598 a rdf:Property ;
rdfs:label "capable of positively regulating" ;
rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002596 .
obo:RO_0002608 a rdf:Property ;
rdfs:label "process has causal agent" ;
rdfs:comment "Inverse of 'causal agent in process'" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002629 a rdf:Property ;
rdfs:label "directly positively regulates" ;
rdfs:comment "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002213 .
obo:RO_0002630 a rdf:Property ;
rdfs:label "directly negatively regulates" ;
rdfs:comment "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002212 .
obo:RO_0004031 a rdf:Property ;
rdfs:label "enables subfunction" ;
rdfs:comment "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 .
obo:RO_0004032 a rdf:Property ;
rdfs:label "acts upstream of or within, positive effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002264 .
obo:RO_0004033 a rdf:Property ;
rdfs:label "acts upstream of or within, negative effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002264 .
obo:RO_0004034 a rdf:Property ;
rdfs:label "acts upstream of, positive effect" ;
rdfs:comment "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004032 , obo:RO_0002263 .
obo:RO_0004035 a rdf:Property ;
rdfs:label "acts upstream of, negative effect" ;
rdfs:comment "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004033 , obo:RO_0002263 .
obo:RO_0004046 a rdf:Property ;
rdfs:label "causally upstream of or within, negative effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002418 .
obo:RO_0004047 a rdf:Property ;
rdfs:label "causally upstream of or within, positive effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002418 .
obo:RO_0012011 a rdf:Property ;
rdfs:label "indirectly causally upstream of"@en ;
rdfs:comment "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002411 .
obo:RO_0012012 a rdf:Property ;
rdfs:label "indirectly regulates"@en ;
rdfs:comment "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0012011 , obo:RO_0002211 .
obo:RO_0017001 a rdf:Property ;
rdfs:label "device utilizes material"@en ;
rdfs:comment "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." ;
rdfs:range .
obo:RO_0019001 a rdf:Property ;
rdfs:label "positively regulates characteristic" ;
rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0019000 .
obo:RO_0019002 a rdf:Property ;
rdfs:label "negatively regulates characteristic" ;
rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0019000 .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
obo:valid_for_go_annotation_extension a rdf:Property ;
rdfs:range xsd:string .
obo:valid_for_go_gp2term a rdf:Property ;
rdfs:range xsd:string .
obo:valid_for_go_ontology a rdf:Property ;
rdfs:range xsd:string .
obo:valid_for_gocam a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:comment "WB phenotype slim" ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range .
a rdf:Property ;
rdfs:range .
a rdf:Property ;
rdfs:range .
a rdf:Property ;
rdfs:range .
a rdf:Property ;
rdfs:range .
obo:IAO_0000078 a rdfs:Class ;
rdfs:label "curation status specification"@en ;
rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
rdfs:subClassOf obo:IAO_0000102 .
obo:IAO_0000002 a obo:IAO_0000078 ;
rdfs:label "example to be eventually removed"@en .
obo:IAO_0000120 a obo:IAO_0000078 ;
rdfs:label "metadata complete"@en ;
rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en .
obo:IAO_0000121 a obo:IAO_0000078 ;
rdfs:label "organizational term"@en ;
rdfs:comment "The term was created to ease viewing/sorting terms for development purposes, but will not be included in a release."@en .
obo:IAO_0000122 a obo:IAO_0000078 ;
rdfs:label "ready for release"@en ;
rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en .
obo:IAO_0000123 a obo:IAO_0000078 ;
rdfs:label "metadata incomplete"@en ;
rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en .
obo:IAO_0000124 a obo:IAO_0000078 ;
rdfs:label "uncurated"@en ;
rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en .
obo:IAO_0000125 a obo:IAO_0000078 ;
rdfs:label "pending final vetting"@en ;
rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en .
obo:IAO_0000423 a obo:IAO_0000078 ;
rdfs:label "to be replaced with external ontology term"@en ;
rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en .
obo:IAO_0000428 a obo:IAO_0000078 ;
rdfs:label "requires discussion"@en ;
rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .
obo:IAO_0000225 a rdfs:Class ;
rdfs:label "obsolescence reason specification"@en ;
rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
rdfs:subClassOf obo:IAO_0000102 .
obo:IAO_0000103 a obo:IAO_0000225 ;
rdfs:label "failed exploratory term"@en ;
rdfs:comment "The term was initially used in an attempt to structure part of the ontology, but in retrospect failed to do a good job."@en .
obo:IAO_0000226 a obo:IAO_0000225 ;
rdfs:label "placeholder removed"@en ;
rdfs:comment "The term was created to temporarily stand in for a semantic purpose, but is no longer needed, typically due to another permanent term being defined."@en .
obo:IAO_0000227 a obo:IAO_0000225 ;
rdfs:label "terms merged"@en ;
rdfs:comment "The term has been combined with one or more other terms to create a more encompassing (merged) term."@en .
obo:IAO_0000228 a obo:IAO_0000225 ;
rdfs:label "term imported"@en ;
rdfs:comment "The term has been replaced by a term imported from another ontology."@en .
obo:IAO_0000229 a obo:IAO_0000225 ;
rdfs:label "term split"@en ;
rdfs:comment "The term has been split into two or more new terms."@en .
obo:OMO_0001000 a obo:IAO_0000225 ;
rdfs:label "out of scope" ;
rdfs:comment "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en .
obo:IAO_0000409 a rdfs:Class ;
rdfs:label "denotator type"@en ;
rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
rdfs:subClassOf obo:IAO_0000102 .
obo:IAO_0000410 a obo:IAO_0000409 ;
rdfs:label "universal"@en .
obo:IAO_0000420 a obo:IAO_0000409 ;
rdfs:label "defined class"@en ;
rdfs:comment "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en .
obo:IAO_0000421 a obo:IAO_0000409 ;
rdfs:label "named class expression"@en ;
rdfs:comment "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en .