PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:VO_0004258 a rdfs:Class ;
  rdfs:label "synthetic MUC1 peptide vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:OBI_0000295 a rdf:Property ;
  rdfs:label "is_specified_input_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:OBI_0000011 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:VO_0003355 a rdf:Property ;
  rdfs:label "immunizes against pathogen" ;
  rdfs:comment """A shortcut relation that is equivalent to:
processed material and (is_specified_output_of some vaccine preparation) and (has function some (vaccine function and (is realized by only (vaccine immunization and (realizes some ('immunization target role' and (role_of some 'pathogen'))))))))

The domain of this relation is a vaccine.
The range of this relation is a pathogen (a bacterium, a virus, a fungus, and a parasite)
Ranges: organism and 'has role' some 'pathogen role'""" ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0000537 a rdf:Property ;
  rdfs:label "vaccine organism secretes" ;
  rdfs:comment "An object property that indicates a secretion of a material (e.g., protein) from a vaccine organism." ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0003390 a rdf:Property ;
  rdfs:label "test in lab animal model" ;
  rdfs:comment """A shortcut relation that is equivalent to:
('vaccine' and 'has function' some ('vaccine function' and ('is realized by' some ('vaccine immunization' and 'has participant' some ('organism' and 'has role' some 'laboratory animal model role'))))).
The domain of this relation is a vaccine.
The range of this relation is a organism.""" ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range obo:OBI_0100026 .

obo:OBI_0000304 a rdf:Property ;
  rdfs:label "is_manufactured_by"@en ;
  rdfs:comment "c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the \"Manufacturer Role\", and those people/and or machines were members or of directed by the organization to do this."@en ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:OBI_0000835 .

obo:VO_0000547 a rdf:Property ;
  rdfs:label "vaccinated in route" ;
  rdfs:comment "An object property that specifies a relation between a vaccine and a vaccinate route" ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range obo:VO_0000574 .

obo:RO_0000085 a rdf:Property ;
  rdfs:label "has function"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000034 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:VO_0001011 a rdf:Property ;
  rdfs:label "immunizes against disease" ;
  rdfs:comment """A shortcut relation that is equivalent to:
'processed material' and (is_specified_output_of some 'vaccine preparation') and ('has function' some ('vaccine function' and ('is realized by' only ('vaccine immunization' and (realizes some ('vaccine host role' and (role_of some 'organism' and has_disposition some disease)))))))).
The domain of this relation is a vaccine.
The range of this relation is a disease.""" ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range obo:DOID_4 .

obo:VO_0003128 a rdf:Property ;
  rdfs:label "has boost vaccine" ;
  rdfs:comment "An object property that represents a relation between a vaccine with a prime-boost schedule and a vaccine used for boost." ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range obo:VO_0000001 .

obo:OBI_0000312 a rdf:Property ;
  rdfs:label "is_specified_output_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:OBI_0000011 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:VO_0000520 a rdf:Property ;
  rdfs:label "has vaccine component" ;
  rdfs:comment "An object property that defines a relation between a vaccine and its component" ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002180 .

obo:RO_0000091 a rdf:Property ;
  rdfs:label "has disposition"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000016 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000056 a rdf:Property ;
  rdfs:label "participates in"@en ;
  rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 .

obo:RO_0002002 a rdf:Property ;
  rdfs:label "has 2D boundary"@en ;
  rdfs:comment "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity"@en ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000141 .

obo:RO_0001025 a rdf:Property ;
  rdfs:label "located in"@en ;
  rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0005242 a rdf:Property ;
  rdfs:label "up-expressed as immune signature of" ;
  rdfs:comment "An object property that represents a relation between a material entity and biological process" ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000015 .

obo:VO_0000553 a rdf:Property ;
  rdfs:label "has vaccinee" ;
  rdfs:comment "An object property that specifies a relation between a vaccine and its vaccinee" ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000087 a rdf:Property ;
  rdfs:label "has role"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000023 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:VO_0001243 a rdf:Property ;
  rdfs:label "immunizes recipient" ;
  rdfs:comment """A shortcut relation that is equivalent to:
'processed material' and (is_specified_output_of some 'vaccine preparation') and ('has function' some ('vaccine function' and ('is realized by' only ('vaccine immunization' and (realizes some ('vaccine recipient role' and (role_of some 'organism')))))))).
The domain of this relation is a vaccine.
The range of this relation is a organism.""" ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0004916 a rdfs:Class ;
  rdfs:label "vaccine specific IL-2 immune response" ;
  rdfs:comment "vaccine-induced T-helper 1 type immune response that is indicated by the presence of interleukin-2 production" ;
  rdfs:subClassOf obo:VO_0000100 .

obo:BFO_0000062 a rdf:Property ;
  rdfs:label "preceded by"@en ;
  rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002086 .

obo:RO_0000059 a rdf:Property ;
  rdfs:label "concretizes"@en ;
  rdfs:comment "A relationship between a specifically dependent continuant or process and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. Multiple specifically dependent continuants or processes can concretize the same generically dependent continuant."@en ;
  rdfs:range obo:BFO_0000031 .

obo:BFO_0000063 a rdf:Property ;
  rdfs:label "precedes"@en ;
  rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:BFO_0000066 a rdf:Property ;
  rdfs:label "occurs in"@en ;
  rdfs:comment "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000004 .

obo:BFO_0000055 a rdf:Property ;
  rdfs:label "realizes"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000017 .

obo:RO_0000057 a rdf:Property ;
  rdfs:label "has participant"@en ;
  rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 .

obo:VO_0007100 a rdfs:Class ;
  rdfs:label "recombinant Fowlpox-Mgp100 vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a replication-defective recombinant fowlpox virus that encodes for the murine melanoma antigen glycoprotein 100 (mgp100) with potential antineoplastic activity. Vaccination with recombinant fowlpox-mgp100 vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:RO_0002180 a rdf:Property ;
  rdfs:label "has component"@en ;
  rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Submissions:Componency> ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:VO_0005563 a rdfs:Class ;
  rdfs:label "microbial eukaryotic vaccine" ;
  rdfs:comment "A vaccine that targets against a microbial eukaryote caused disease." ;
  rdfs:subClassOf obo:VO_0005504 .

obo:VO_0002203 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, C2 Strain, Mass Type, Live Virus Vaccine (USDA: 1XB1.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0017176 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] Box of 50" ;
  rdfs:subClassOf obo:VO_0017171 , obo:VO_0017187 , obo:VO_0017623 .

obo:VO_0015018 a rdf:Property ;
  rdfs:label "has drug package" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0015007 a rdf:Property ;
  rdfs:label "has drug dose form" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0015002 a rdf:Property ;
  rdfs:label "has drug brand name" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0015211 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 10" ;
  rdfs:subClassOf obo:VO_0015207 , obo:VO_0015215 , obo:VO_0015303 .

obo:VO_0000053 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis vaccine" ;
  rdfs:comment "Vaccine that protects against Neisseria meningitidis infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003484 .

obo:VO_0018215 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus 1000 UNT / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2000 PFU Injection [Priorix]" ;
  rdfs:subClassOf obo:VO_0018213 , obo:VO_0018214 .

obo:VO_0000531 a rdf:Property ;
  rdfs:label "has vaccine allergen" ;
  rdfs:comment "An object property that specifies a relation between a vaccine and a vaccine allergen" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0015887 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 20" ;
  rdfs:subClassOf obo:VO_0015619 , obo:VO_0016004 .

obo:VO_0000525 a rdf:Property ;
  rdfs:label "has subunit vaccine antigen" ;
  rdfs:comment "A type of 'has vaccine antigen' relation that is specifically for vaccine protective protein antigen used in subunit vaccine development" ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:VO_0000524 .

obo:VO_0002046 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1288.45)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0011047 a rdfs:Class ;
  rdfs:label "FspA1" ;
  rdfs:comment "Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model.  Immunization with FspA1 resulted in 57.8% protection without adjuvant or 63.8% protection with adjuvant against homologous challenge with 81-176 [PubMed: 18426878]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010765 .

obo:VO_0015142 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015141 .

obo:VO_0017360 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0017358 .

obo:VO_0005079 a rdfs:Class ;
  rdfs:label "AV-COVID-19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 vaccine consisting of autologous dendritic cells previously loaded ex vivo with spike protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0002876 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine" ;
  rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0002394 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2 vaccine" ;
  rdfs:subClassOf obo:VO_0001471 , obo:VO_0001490 , obo:VO_0012178 .

obo:VO_0020613 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML Injection [Varivax] by Merck" ;
  rdfs:subClassOf obo:VO_0015029 .

obo:VO_0000257 a rdfs:Class ;
  rdfs:label "pET-28a DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:label "part of"@en ;
  rdfs:comment "a core relation that holds between a part and its whole"@en ;
  rdfs:seeAlso <http://www.obofoundry.org/ro/#OBO_REL:part_of> ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0017010 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 100" ;
  rdfs:subClassOf obo:VO_0017003 , obo:VO_0017021 , obo:VO_0017492 .

obo:VO_0020701 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020700 .

obo:VO_0015486 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015499 .

obo:VO_0004432 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine VR-S8/VR-IL2/AD-S8 encoding survivin" ;
  rdfs:comment "Gene name: Survivin" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:NCBITaxon_149595 a rdfs:Class ;
  rdfs:label "Canine parainfluenza virus" ;
  rdfs:subClassOf obo:NCBITaxon_11158 .

obo:OPL_0000174 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum microgamete" ;
  rdfs:comment "A Plasmodium falciparum gamete that is a matured form of exflagellated microgametocyte and found in the midgut of a mosquito vector. The microgamete fertilizes the macrogamete, forming the zygote." ;
  rdfs:subClassOf obo:OPL_0000258 , obo:OPL_0000266 .

obo:VO_0003761 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2016-2017 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003758 .

obo:VO_0010396 a rdf:Property ;
  rdfs:label "has flu season" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0002517 a rdfs:Class ;
  rdfs:label "apxIC from Actinobacillus pleuropneumoniae" ;
  rdfs:comment "In the intra-peritoneal mouse model, the virulence of the mutant strain decreased at least 100 fold compared with the parent strain. The mutant was evaluated as a potential vaccine using a vaccination-challenge trial. The death number and lung lesion score in the vaccinated pigs given the serovar 1 challenge were obviously lower than those in the unvaccinated pigs" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001384 .

obo:RO_0002162 a rdf:Property ;
  rdfs:label "in taxon" ;
  rdfs:comment "x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002320 .

obo:VO_0011014 a rdfs:Class ;
  rdfs:label "Psn" ;
  rdfs:comment "Study tested the efficacy of 2 proteins, Psn and a portion of LcrV in protecting mice against virulent Yersinia pestis challenge.  Results show that the truncated LcrV protein delivered by RASV is sufficient to afford a full protective immune response in a mouse model of bubonic plague and the Psn protein afforded partial protection in a non-optimized system [PubMed: 17966435]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:OPL_0000113 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum oocyst stage" ;
  rdfs:comment "An oocyst stage in the Plasmodium falciparum lifecycle that occurs on the hemocoel side of the midgut of a mosquito vector. During this stage Plasmodium falciparum ookinete invades and escapes midgut wall of mosquito and embed itself onto the exterior of the gut membrane and develop encysted zygote, called oocyst." ;
  rdfs:subClassOf obo:OPL_0000073 , obo:OPL_0000165 , obo:OPL_0000295 .

obo:VO_0001979 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:VO_0015543 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Suspension [VACCIN GENHEVAC B]" ;
  rdfs:subClassOf obo:VO_0003416 .

obo:VO_0015768 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015588 .

obo:VO_0021017 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0021013 .

obo:VO_0001822 a rdfs:Class ;
  rdfs:label "Escherichia coli avirulent live culture vaccine (USDA: 15R1.00)" ;
  rdfs:subClassOf obo:VO_0000125 , obo:VO_0000455 , obo:VO_0000619 , obo:VO_0007748 .

obo:VO_0000819 a rdfs:Class ;
  rdfs:label "recombinant HIV gp120 with adjuvant NanoEmulsion vaccine" ;
  rdfs:comment "A HIV vaccine that is made of recombinant HIV gp120 protein adjuvanted with the adjuvant NanoEmulsion. PMID:18260780." ;
  rdfs:subClassOf obo:VO_0000295 , obo:VO_0000484 .

obo:VO_0017882 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.05 MG" ;
  rdfs:subClassOf obo:VO_0015069 .

obo:VO_0005456 a rdfs:Class ;
  rdfs:label "Diphtheria-Pertussis-Tetanus-Haemophilus B-Hepatitis B vaccine,(Pentavalent)" ;
  rdfs:subClassOf obo:VO_0000738 , obo:VO_0000746 , obo:VO_0010437 , obo:VO_0010439 .

obo:VO_0021003 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 UNT Injectable Solution" ;
  rdfs:subClassOf obo:VO_0021001 , obo:VO_0021040 .

obo:VO_0000286 a rdfs:Class ;
  rdfs:label "vaccine-induced gene response" ;
  rdfs:subClassOf obo:VO_0000288 .

obo:VO_0015757 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Lt Grk] Box of 25" ;
  rdfs:subClassOf obo:VO_0015579 , obo:VO_0015814 .

obo:VO_0005436 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, bivalent booster, preservative free, 30 mcg/0.3 mL dose, tris-sucrose formulation" ;
  rdfs:comment "A Comirnaty COVID-19 mRNA vaccine utilizes Lipid Nanoparticle-Self-amplifying RNA technology, available as a bivalent boosters against the original strain of COVID-19 as well as the Omicron BA.1 variant produced by Pfizer (PF) with a dose of 30 mcg/0.3 mL to provide enhanced protection." ;
  rdfs:subClassOf obo:VO_0004987 .

obo:VO_0006031 a rdfs:Class ;
  rdfs:label "meningococcal ACWY vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0020596 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Viroflu] Box of 10" ;
  rdfs:subClassOf obo:VO_0020595 , obo:VO_0020603 , obo:VO_0020881 .

obo:VO_0004390 a rdfs:Class ;
  rdfs:label "Marburg virus DNA vaccine DNA-GP encoding GP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012163 .

obo:VO_0007081 a rdfs:Class ;
  rdfs:label "EP-2101 Vaccine" ;
  rdfs:comment "A proprietary cancer DNA vaccine that contains multiple natural and modified epitopes derived from the four tumor associated antigens, CEA, HER2/neu, p53, and MAGE 2/3. OSE 2101 also includes CAP1-6D, a heteroclitic CEA analog, and PADRE, a proprietary universal T-cell epitope that serves to enhance the immunogenicity of the epitopes. This agent has been shown to elicit cytotoxic T-lymphocyte responses against tumor cells expressing these multiple epitopes." ;
  rdfs:subClassOf obo:VO_0005486 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0000328 a rdfs:Class ;
  rdfs:label "pV1J DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0020192 a rdfs:Class ;
  rdfs:label "rubella virus vaccine live (Wistar RA 27-3 strain) Injectable Solution [Meruvax II]" ;
  rdfs:subClassOf obo:VO_0000073 , obo:VO_0018807 .

obo:VO_0018443 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 20" ;
  rdfs:subClassOf obo:VO_0018423 .

obo:VO_0016629 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0016607 , obo:VO_0016617 .

obo:VO_0003427 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0015490 .

obo:VO_0015328 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Prefilled Syringe [ViATIM]" ;
  rdfs:subClassOf obo:VO_0015327 .

obo:VO_0019602 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020303 .

obo:VO_0017328 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0003095 , obo:VO_0017327 .

obo:VO_0018293 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Injectable Suspension [Tollwut-Impfstoff]" ;
  rdfs:subClassOf obo:VO_0018279 , obo:VO_0018297 .

obo:NCBITaxon_666 a rdfs:Class ;
  rdfs:label "Vibrio cholerae" ;
  rdfs:subClassOf obo:NCBITaxon_662 .

obo:VO_0015943 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 100" ;
  rdfs:subClassOf obo:VO_0015638 , obo:VO_0015717 , obo:VO_0016041 .

obo:VO_0021082 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Quadracel]" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0010736 .

obo:VO_0007501 a rdfs:Class ;
  rdfs:label "MART-1 vaccine" ;
  rdfs:comment "Gene name: gp100" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0000717 a rdfs:Class ;
  rdfs:label "subunit vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:OBI_0000299 a rdf:Property ;
  rdfs:label "has_specified_output"@en ;
  rdfs:comment "The inverse property of is_specified_output_of"@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OBI_0000417 a rdf:Property ;
  rdfs:label "achieves_planned_objective" ;
  rdfs:comment "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process."@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:IAO_0000005 .

obo:OBI_0000293 a rdf:Property ;
  rdfs:label "has_specified_input"@en ;
  rdfs:comment "The inverse property of is_specified_input_of"@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000002 , obo:BFO_0000040 , obo:IAO_0000027 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:VO_0019339 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0003441 , obo:VO_0010444 , obo:VO_0010445 .

obo:VO_0020477 a rdfs:Class ;
  rdfs:label "Fluvirin 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000046 , obo:VO_0010417 .

obo:NCBITaxon_12058 a rdfs:Class ;
  rdfs:label "Picornaviridae" ;
  rdfs:subClassOf obo:NCBITaxon_464095 .

obo:VO_0018403 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 18C vaccine 0.004 MG" ;
  rdfs:subClassOf obo:VO_0003222 .

obo:NCBITaxon_138950 a rdfs:Class ;
  rdfs:label "Enterovirus C" ;
  rdfs:subClassOf obo:NCBITaxon_12059 .

obo:VO_0004580 a rdfs:Class ;
  rdfs:label "HRSV DNA vaccine pND-G" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002512 .

obo:VO_0005106 a rdfs:Class ;
  rdfs:label "SARS tPA-S DNA vaccine" ;
  rdfs:comment "A SARS DNA vaccine that is made from tpa-optimize800 DNA with SARS-CoV S protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012183 .

obo:VO_0005425 a rdfs:Class ;
  rdfs:label "prostate cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is used against prostate cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:NCBITaxon_3044782 a rdfs:Class ;
  rdfs:label "Orthoflavivirus" ;
  rdfs:subClassOf obo:NCBITaxon_11050 .

obo:VO_0003391 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003196 .

obo:VO_0018199 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0018357 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003340 .

obo:VO_0002980 a rdfs:Class ;
  rdfs:label "influenza virus CTA1-3M2e-DD protein vaccine" ;
  rdfs:comment "Mutant influenza virus that lacks the transmembrane and cytoplasmic tail domains of M2 (M2 knockout [M2KO]) from Influenza A virus (A/Puerto Rico/8/34(H1N1)) is attenuated in both cell culture and mice. Mice intranasally vaccinated with M2KO virus developed protective immune responses and survived a lethal challenge with the wild-type virus, suggesting that the M2KO virus has potential as a live attenuated vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0001984 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002360 .

obo:VO_0003041 a rdfs:Class ;
  rdfs:label "neomycin residual" ;
  rdfs:comment "an antibiotics vaccine residual that has the antibiotics of neomycin. " ;
  rdfs:subClassOf obo:VO_0000704 .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has part"@en ;
  rdfs:comment "a core relation that holds between a whole and its part"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0003721 a rdfs:Class ;
  rdfs:label "Afluria 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000006 , obo:VO_0000578 , obo:VO_0010432 .

obo:VO_0003626 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003623 .

obo:VO_0020444 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1" ;
  rdfs:subClassOf obo:VO_0020410 , obo:VO_0020421 .

obo:VO_0001257 a rdfs:Class ;
  rdfs:label "prevention of disorder objective" ;
  rdfs:comment "The specification of an objective to prevent a disorder." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0000833 a rdf:Property ;
  rdfs:label "objective_achieved_by" ;
  rdfs:comment "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process."@en ;
  rdfs:domain obo:IAO_0000005 ;
  rdfs:range obo:OBI_0000011 .

obo:OBI_0001938 a rdf:Property ;
  rdfs:label "has value specification" ;
  rdfs:comment "A relation between an information content entity and a value specification that specifies its value."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range obo:OBI_0001933 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0000058 a rdf:Property ;
  rdfs:label "is concretized as"@en ;
  rdfs:comment "A relationship between a generically dependent continuant and a specifically dependent continuant or process, in which the generically dependent continuant depends on some independent continuant or process in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants or processes."@en ;
  rdfs:domain obo:BFO_0000031 ;
  rdfs:range xsd:string .

obo:DOID_934 a rdfs:Class ;
  rdfs:label "viral infectious disease"@en ;
  rdfs:comment "A disease by infectious agent that results in infection, has_material_basis_in Viruses."@en ;
  rdfs:subClassOf obo:DOID_0050117 .

obo:BFO_0000054 a rdf:Property ;
  rdfs:label "realized in"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000017 ;
  rdfs:range obo:BFO_0000015 , obo:OBI_0000274 , obo:OBI_0000685 , obo:GO_0006955 , obo:OBI_0000457 , obo:OGMS_0000063 , obo:OBI_0000070 .

obo:VO_0000147 a rdfs:Class ;
  rdfs:label "vaccine adjuvant role" ;
  rdfs:comment "an adjuvant role that inheres in a vaccine component which is added as part of a vaccine and induces enhanced adaptive immune response to the vaccine antigen. " ;
  rdfs:subClassOf obo:VO_0000415 .

obo:VO_0019389 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [Certiva]" ;
  rdfs:subClassOf obo:VO_0003122 , obo:VO_0017799 , obo:VO_0018770 .

obo:VO_0001105 a rdfs:Class ;
  rdfs:label "Lawsonia intracellularis vaccine" ;
  rdfs:comment "Vaccine that protects against Lawsonia intracellularis infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 , obo:VO_0001474 .

obo:NCBITaxon_117571 a rdfs:Class ;
  rdfs:label "Euteleostomi" ;
  rdfs:subClassOf obo:NCBITaxon_7742 .

obo:VO_0002481 a rdfs:Class ;
  rdfs:label "Trichomonas Foetus-Campylobacter Fetus-Leptospira vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000391 , obo:VO_0000568 , obo:VO_0001457 , obo:VO_0001466 .

obo:VO_0011235 a rdfs:Class ;
  rdfs:label "OmpB" ;
  rdfs:comment "R. rickettsii OmpB contain B and T lymphocyte epitopes. Immunizations with each of two fragments from OmpB (rompB1550-2738 and rompB2459-4123) conferred protection against challenge with a lethal dose of R. conorii. Protection appeared to be better achieved among the groups that received both DNA and recombinant protein immunizations, although recombinant protein immunizations alone provided some protection [PubMed: 11693887]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010846 .

obo:VO_0007061 a rdfs:Class ;
  rdfs:label "pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine" ;
  rdfs:comment "An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock protein 70 (HSP70). Upon administration, this vaccine may generate potent cytotoxic CD8(+) T-cell responses against E7-expressing tumor cells, resulting in tumor cell death." ;
  rdfs:subClassOf obo:VO_0005488 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0003803 a rdfs:Class ;
  rdfs:label "Varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010328 .

obo:VO_0018153 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 20" ;
  rdfs:subClassOf obo:VO_0018150 , obo:VO_0018157 .

obo:VO_0005451 a rdfs:Class ;
  rdfs:label "licensed human Rho(D) immune globulin passive vaccine" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0015904 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1" ;
  rdfs:subClassOf obo:VO_0003267 .

obo:VO_0003947 a rdfs:Class ;
  rdfs:label "CERVARIX 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003946 .

obo:VO_0003230 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0000510 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae rTbpB vaccine" ;
  rdfs:subClassOf obo:VO_0000471 .

obo:VO_0001408 a rdfs:Class ;
  rdfs:label "Aeromonas salmonicida gene" ;
  rdfs:comment "A bacterial gene that is from Aeromonas salmonicida." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0017334 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injection [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0017332 .

obo:VO_0002995 a rdfs:Class ;
  rdfs:label "ick-borne Encephalitis Virus C protein mutant vaccine" ;
  rdfs:comment "A virus with a mutation in protein C is attenuated in mice and induced protection from challenge with wild type TBE virus" ;
  rdfs:subClassOf obo:VO_0012190 .

obo:VO_0015583 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix]" ;
  rdfs:subClassOf obo:VO_0015541 , obo:VO_0015598 .

obo:VO_0005164 a rdfs:Class ;
  rdfs:label "ARCT-021 vaccine" ;
  rdfs:comment "A SARS-CoV-2 investigational vaccine comprising a self-replicating (replicon) mRNA that encodes for the prefusion spike protein of 2019-nCoV formulated in a lipid nanoparticle" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0002184 a rdfs:Class ;
  rdfs:label "Newcastle-Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 17P5.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002458 , obo:VO_0007748 .

obo:VO_0004927 a rdfs:Class ;
  rdfs:label "human age range at vaccination" ;
  rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ;
  rdfs:subClassOf obo:VO_0004926 .

obo:VO_0011095 a rdfs:Class ;
  rdfs:label "HBVgp2 pre-S1/pre-S2/S" ;
  rdfs:comment "Immunisation with a plasmid encoding the DHBV large (L) envelope protein (HBVgp2 pre-S1/pre-S2/S) induced a strong, specific, highly neutralising and long-lasting anti-preS humoral response in uninfected ducks. Importantly, maternal antibodies elicited by such DNA immunisation were vertically transmitted and protected progeny against viral challenge [PubMed: 12531335]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010781 .

obo:OBI_0000094 a rdfs:Class ;
  rdfs:label "material processing"@en ;
  rdfs:comment "A planned process which results in physical changes in a specified input material"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0017034 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0017033 .

obo:VO_0000322 a rdfs:Class ;
  rdfs:label "pTR600 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007021 a rdfs:Class ;
  rdfs:label "Synthetic Breast Cancer Peptides-Tetanus Toxoid-Montanide ISA-51 Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of multiple synthetic breast cancer peptides and the adjuvant tetanus toxoid helper peptide emulsified in the adjuvant Montanide ISA-51 with immunopotentiation activity. Vaccination with this cancer vaccine may elicit a specific cytotoxic T-lymphocyte response against breast cancer cells. Synthetic breast cancer peptides may stimulate the immune response against cells that produce breast cancer markers such as erbB2 (HER2/neu) while tetanus toxoid helper peptide binds to class II MHC molecules as a nonspecific vaccine helper epitope, resulting in a long-term immunopotentiation by increasing the helper T-cell response. Montanide ISA-51, also known as incomplete Freund's adjuvant or IFA, is a stabilized water-in-oil emulsion adjuvant containing mineral oil with mannide oleate added as a surfactant that non-specifically stimulates cell-mediated immune responses to antigens." ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000577 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0015720 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015572 , obo:VO_0015799 .

obo:VO_0002340 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0001507 , obo:VO_0002338 .

obo:VO_0020004 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:NCBITaxon_996 a rdfs:Class ;
  rdfs:label "Flavobacterium columnare" ;
  rdfs:subClassOf obo:NCBITaxon_200644 .

obo:VO_0017447 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injectable Solution [HibTITER]" ;
  rdfs:subClassOf obo:VO_0000659 , obo:VO_0017445 .

obo:VO_0010218 a rdfs:Class ;
  rdfs:label "rotavirus, live, monovalent vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010449 .

obo:VO_0004723 a rdfs:Class ;
  rdfs:label "pRP-RSV-HSV-2-gB vaccine" ;
  rdfs:subClassOf obo:VO_0012168 .

obo:VO_0020379 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Delayed Release Oral Capsule [Vivotif Berna]" ;
  rdfs:subClassOf obo:VO_0003447 .

obo:VO_0000622 a rdfs:Class ;
  rdfs:label "vaccine protective antigen role" ;
  rdfs:comment "a vaccine antigen role that inheres in a vaccine antigen which is capable of inducing protective immunity. " ;
  rdfs:subClassOf obo:VO_0000618 .

obo:VO_0005442 a rdfs:Class ;
  rdfs:label "licensed human hepatitis A immune globulin passive vaccine" ;
  rdfs:comment """Hepatitis A Immune Globulin passive vaccine is a
 passive vaccine that provides protection against hepatitis 
A through the passive transfer of an antibody. Hep A, IG provides
 temporary immunity to the virus for two to three months, if 
administered prior to exposure or within two weeks after exposure.""" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0002957 a rdfs:Class ;
  rdfs:label "Equid herpesvirus TK mutant vaccine" ;
  rdfs:comment "A thymidine kinase-deficient mutant (PR1) is attenuated in mice and induced significant protection from challenge with wild type EHV-1 5 weeks after vaccination. In foals, PR1 also showed attenuation; however, the mutant induced only partial protection from challenge with EHV-1" ;
  rdfs:subClassOf obo:VO_0001486 .

obo:VO_0000119 a rdfs:Class ;
  rdfs:label "Varivax vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000419 , obo:VO_0000455 .

obo:VO_0005337 a rdfs:Class ;
  rdfs:label "UM-3005 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that includes UM-3005, a small molecule TLR7/8 agonist that can stimulate Th1-biased immune profile." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0005312 a rdf:Property ;
  rdfs:label "induces immune profile" ;
  rdfs:comment "An object property that represents a relation between a material entity (such as vaccine or vaccine adjuvant) and an immune profile where the material entity can induce the immune profile in a host." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0002652 a rdfs:Class ;
  rdfs:label "ompR from Salmonella Typhimurium" ;
  rdfs:comment "An ompR mutant is attenuated in mice after oral challenge. Twenty eight days after immunization, mice were challenged with wild type S. typhimurium and were significantly protected" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0005023 a rdfs:Class ;
  rdfs:label "VR2210 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label VR2210.  This plasmid contains a CMV promoter and kanamycin resistance gene.  It was created through ligation of fragments of digested plasmid VR1012, hTPA, and B. burgdorferi B31 ospA." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019683 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0000740 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum vaccine combination B" ;
  rdfs:comment "A malaria vaccine that comprises recombinant Plasmodium falciparum (P. falciparum) blood-stage proteins MSP1, MSP2 and RESA, formulated with the adjuvant Montanide ISA 720." ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000641 .

obo:VO_0002629 a rdfs:Class ;
  rdfs:label "crp from Salmonella Gallinarum" ;
  rdfs:comment "A crp mutant is attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001420 .

obo:VO_0003625 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine 0.25 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003623 .

obo:VO_0016695 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 150 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0010160 a rdfs:Class ;
  rdfs:label "diphtheria, tetanus toxoids and acellular pertussis vaccine, 5 pertussis antigens" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 .

obo:VO_0007379 a rdfs:Class ;
  rdfs:label "DNA vector pPRA-PSM vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a DNA plasmid encoding epitopes of the human preferential antigen of melanoma (PRAME) and the prostate specific membrane antigen (PSMA) with potential immunostimulating activity. Upon direct administration of this vaccine into lymph nodes, peptides expressed by DNA plasmid vector pPRA-PSM may activate the immune system, resulting in a cytotoxic T-lymphocyte (CTL) response against PRAME- and PSMA-expressing cells. PRAME and PSMA are tumor associated antigens upregulated in a number of cancer cell types. As part of the MKC1106-PP regimen exploiting the 'prime-boost strategy', this plasmid is responsible for priming the immune response and is used in conjunction with a peptide vaccine consisting of PRAME and PSMA that boosts the immune system against PRAME- and PSMA-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:OPL_0000153 a rdfs:Class ;
  rdfs:label "ookinete stage" ;
  rdfs:comment "A parasite lifecycle stage of some sporozoans where motile and elongated zygote is formed by the fertilization of the macrogamete during the sexual reproductive phase of the sporozoan life cycle, specifically the malarial parasite Plasmodium." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0011357 a rdfs:Class ;
  rdfs:label "Bordetella pertussis Cpn60 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0015659 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015595 .

obo:VO_0004241 a rdfs:Class ;
  rdfs:label "Leishmania donovani recombinant Ld-Gamma-GCS in NIV system vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0001142 .

obo:VO_0015836 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 3 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015608 .

obo:VO_0017975 a rdfs:Class ;
  rdfs:label "0.6 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0017945 , obo:VO_0017959 .

obo:VO_0001574 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Modified Live Virus Vaccine (USDA: 1201.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0001501 .

obo:VO_0003133 a rdfs:Class ;
  rdfs:label "MRKAd5 HIV-1 gag/pol/nef vaccine" ;
  rdfs:comment "The MRK adenovirus type 5 human immunodeficiency virus type 1 clade B gag/pol/nef vaccine is a replication-incompetent adenovirus type 5-vectored vaccine that elicits cell-mediated immunity against conserved human immunodeficiency virus proteins." ;
  rdfs:subClassOf obo:VO_0000295 .

obo:NCBITaxon_29461 a rdfs:Class ;
  rdfs:label "Brucella suis" ;
  rdfs:subClassOf obo:NCBITaxon_234 .

obo:VO_0003835 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003834 .

obo:VO_0020682 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0010477 a rdfs:Class ;
  rdfs:label "licensed human coxiella burnetii vaccine" ;
  rdfs:comment "Coxiella burnetii vaccine that is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000463 , obo:VO_0000635 .

obo:VO_0005243 a rdfs:Class ;
  rdfs:label "CoviVac (Russia)" ;
  rdfs:comment "A SARS-CoV-2 inactivated whole virus vaccine developed by the Chumakov Centre at the Russian Academy of Sciences" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0002105 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0018380 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML [Pneumovax 23]" ;
  rdfs:subClassOf obo:VO_0003323 .

obo:NCBITaxon_11246 a rdfs:Class ;
  rdfs:label "Bovine orthopneumovirus" ;
  rdfs:subClassOf obo:NCBITaxon_1868215 .

obo:NCBITaxon_150052 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica subsp. enterocolitica" ;
  rdfs:subClassOf obo:NCBITaxon_629 .

obo:VO_0019336 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group B vaccine 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 0.05 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003347 .

obo:VO_0016949 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 4 LFU/ML Injection Box of 10 by Massbiologics" ;
  rdfs:subClassOf obo:VO_0016948 .

obo:VO_0002683 a rdfs:Class ;
  rdfs:label "obsolete virG from Shigella" ;
  rdfs:comment "A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei" .

obo:VO_0010439 a rdfs:Class ;
  rdfs:label "licensed human hepatitis B virus vaccine" ;
  rdfs:comment "Hepatitis B virus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000644 .

obo:VO_0007271 a rdfs:Class ;
  rdfs:label "APC8015F vaccine" ;
  rdfs:comment "A cell-based vaccine composed of previously frozen autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0007004 a rdfs:Class ;
  rdfs:label "PF-04948568 Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a human epidermal growth factor receptor variant III (EGFRvIIi)-specific peptide conjugated to the non-specific immunomodulator keyhole limpet hemocyanin (KLH) with potential antineoplastic activity. Vaccination with rindopepimut may elicit a cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing EGFRvIII. EGFRvIII, a functional variant of EGFR that is not expressed in normal tissues, was originally discovered in glioblastoma multiforme (GBM) and has also been found in various other cancers such as breast, ovarian, metastatic prostate, colorectal, and head and neck cancers. EGFRvIII contains an 83 amino acid deletion in its extracellular domain and has been shown to transform NIH/3T3 mouse embryonic fibroblast cells in vitro." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0017570 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0017553 , obo:VO_0017555 .

obo:VO_0000866 a rdfs:Class ;
  rdfs:label "Fluviral S/F vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0002495 , obo:VO_0010415 .

obo:VO_0005124 a rdfs:Class ;
  rdfs:label "MERS rNTD vaccine" ;
  rdfs:comment "A MERS subunit vaccine made of a neutralizing monoclonal antibodiesagainst MERS-CoV which bind to the N-terminal domain (NTD) of the MERS-CoV S1 subunit that was expressed by baculovirus-insect cell sf9-derived recombinant MERS-CoV." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0005137 a rdfs:Class ;
  rdfs:label "MVA-MERS vaccine" ;
  rdfs:comment "A MERS VLP vaccine made from  a recombinant baculovirus co-expresssing the spike S, envelope (E), and membrane (M) proteins of MERS." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0000644 a rdfs:Class ;
  rdfs:label "Hepatitis B virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Hepatitis B virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003540 .

obo:VO_0000844 a rdfs:Class ;
  rdfs:label "Art Vax vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001114 .

obo:VO_0018589 a rdfs:Class ;
  rdfs:label "5 ML Anthrax Vaccine Adsorbed 0.1 MG/ML Injectable Suspension [Biothrax]" ;
  rdfs:subClassOf obo:VO_0004215 , obo:VO_0018588 , obo:VO_0018596 .

obo:VO_0002072 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 12J5.43)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002367 , obo:VO_0007748 .

obo:VO_0000300 a rdfs:Class ;
  rdfs:label "Brucella melitensis strain VTRM1 vaccine" ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0016103 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Mtk" ;
  rdfs:subClassOf obo:VO_0015993 .

obo:VO_0018757 a rdfs:Class ;
  rdfs:label "Vaccine, Typh.-Paratyph.A & B" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010451 .

obo:VO_0007137 a rdfs:Class ;
  rdfs:label "pUMVC3-hIGFBP-2 Multi-Epitope Plasmid DNA Vaccine" ;
  rdfs:comment "A plasmid DNA vaccine containing mammalian expression vector pUMVC3, encoding epitopes of human insulin-like growth factor-binding protein 2 (hIGFBP-2) with potential immunostimulating and antineoplastic activities. Upon vaccination, pUMVC3-hIGFBP-2 multi-epitope plasmid DNA vaccine may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against hIGFBP-2-expressing cells. The tumor associated antigen (TAA) hIGFBP-2, a member of the insulin like growth factor receptor family, is overexpressed in a number of cancer cell types and its expression has been associated with increased invasiveness." ;
  rdfs:subClassOf obo:VO_0005493 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0003030 a rdfs:Class ;
  rdfs:label "gelatin" ;
  rdfs:comment "Gelatin is a mixture of peptides and proteins produced by partial hydrolysis of collagen extracted from the skin, boiled crushed bones, connective tissues, organs and some intestines of animals such as domesticated cattle, chicken, and pigs.(wikipedia)" ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0007248 a rdfs:Class ;
  rdfs:label "a2/4-1bbl melanoma vaccine" ;
  rdfs:comment "A cancer vaccine used to treat patients with malignant melanoma. It is made of a compatible melanoma cell line that has been engineered to express a molecule termed 4-1BBL, which enhances the chances of the cell line to be recognized by the patient's immune system, and to induce its stimulation, with an immune response to residual tumor in the body. It will be used in combination with intravenous low dose cyclophosphamide, 300 mg/m2." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007658 .

obo:OGG_0000000002 a rdfs:Class ;
  rdfs:label "gene"@en ;
  rdfs:comment "A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. " ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0018797 a rdfs:Class ;
  rdfs:label "Human Papillomavirus 16/18 L1 virus vaccine" ;
  rdfs:subClassOf obo:VO_0000667 .

obo:VO_0010829 a rdfs:Class ;
  rdfs:label "Giardia duodenalis protein" ;
  rdfs:subClassOf obo:VO_0005477 .

obo:VO_0004421 a rdfs:Class ;
  rdfs:label "VEE virus DNA vaccine VEEV IA/B parent encoding structural genes" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001499 .

obo:VO_0000297 a rdfs:Class ;
  rdfs:label "pNL3-gal DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016676 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0003429 .

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:RO_0000079 a rdf:Property ;
  rdfs:label "function of"@en ;
  rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000034 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:VO_0005203 a rdfs:Class ;
  rdfs:label "COVID-19 DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0004908 .

obo:VO_0019097 a rdfs:Class ;
  rdfs:label "oral product" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:VO_0011401 a rdfs:Class ;
  rdfs:label "Sin Nombre virus DNA vaccine encoding G1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012167 .

obo:RO_0002292 a rdf:Property ;
  rdfs:label "expresses"@en ;
  rdfs:comment "y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process." ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002330 .

obo:VO_0003811 a rdfs:Class ;
  rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen" ;
  rdfs:comment "CUI: C4276025" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0000434 a rdfs:Class ;
  rdfs:label "Mixed Bacterial Vaccine" ;
  rdfs:comment "Mixed Bacterial Vaccine (MBV, Coley's Toxins) is a historical, vaguely defined preparation of heat-inactivated Streptococcus pyogenes and Serratia marcescens used as non-specific immunotherapy in the treatment of cancer." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0018502 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018427 .

obo:VO_0004020 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding HA from influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1))" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0017390 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 12.5 LFU/ML / tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0017472 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017470 , obo:VO_0017471 .

obo:VO_0010207 a rdfs:Class ;
  rdfs:label "pneumococcal polysaccharide vaccine, 23 valent" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0003830 a rdfs:Class ;
  rdfs:label "Havrix Injection" ;
  rdfs:subClassOf obo:VO_0003826 .

obo:VO_0001088 a rdfs:Class ;
  rdfs:label "murine leukemia viral vector vaccine" ;
  rdfs:comment "a viral vaccine vector that uses a murine leukemia virus as the vaccine vector" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0001144 a rdfs:Class ;
  rdfs:label "Brucella DNA vaccine encoding chimera BLSOmp31" ;
  rdfs:subClassOf obo:VO_0001226 .

obo:VO_0006016 a rdfs:Class ;
  rdfs:label "licensed human hepatitis C vaccine" ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0003546 .

obo:VO_0004011 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis ExbB protein vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0007538 a rdfs:Class ;
  rdfs:label "MAGE-1 Vaccinia contaminated with bovine viral diarrhea virus vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant vaccinia virus encoding the tumor-associated gene MAGE-1 that is contaminated with bovine viral diarrhea virus (BVDV). The MAGE-1 gene is a member of the melanoma antigen-encoding gene family which is expressed in various malignant tumors such as hepatocellular carcinoma and germ cell tumors in addition to melanoma. Vaccination with vaccinia virus expressing human MAGE-1 may generate antitumoral T-cell responses. BVDV is an RNA pestivirus that may contaminate vaccines due to its presence in the fetal calf serum used as a growth supplement in the tissue culture of mammalian cells used in vaccine production." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0004885 a rdfs:Class ;
  rdfs:label "Menomune A/C/Y/W-135 Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0004870 , obo:VO_0020131 .

obo:VO_0000246 a rdfs:Class ;
  rdfs:label "edible" ;
  rdfs:comment "A quality of edibility that inheres in a bearer by virtue of the bearer being suitable for oral ingestion as food, drug, or vaccine." ;
  rdfs:subClassOf obo:VO_0000245 .

obo:VO_0019613 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluarix Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020322 .

obo:VO_0003337 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0002390 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0002391 .

obo:VO_0001451 a rdfs:Class ;
  rdfs:label "Plasmodium berghei gene" ;
  rdfs:comment "A Plasmodium gene that is from Plasmodium berghei." ;
  rdfs:subClassOf obo:VO_0000171 .

obo:VO_0016044 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 3" ;
  rdfs:subClassOf obo:VO_0015669 , obo:VO_0015799 .

obo:VO_0000003 a rdfs:Class ;
  rdfs:label "ACAM2000 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000433 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010452 .

obo:VO_0000878 a rdfs:Class ;
  rdfs:label "RECOMBITEKEquine WNV vaccine" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000752 .

obo:VO_0004712 a rdfs:Class ;
  rdfs:label "rMV- WNV vaccine" ;
  rdfs:subClassOf obo:VO_0000752 .

obo:VO_0018269 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT" ;
  rdfs:subClassOf obo:VO_0003857 .

obo:VO_0007118 a rdfs:Class ;
  rdfs:label "tyrosinase240-251S, 368-376D vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0016956 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017417 .

obo:VO_0004874 a rdfs:Class ;
  rdfs:label "Adenovirus Type 4 Vaccine Live Delayed Release Oral Tablet" ;
  rdfs:subClassOf obo:VO_0004873 .

obo:VO_0001956 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002361 .

obo:VO_0019667 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0003226 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 20 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0001138 a rdfs:Class ;
  rdfs:label "Ovilis Toxovax vaccine" ;
  rdfs:subClassOf obo:VO_0000994 , obo:VO_0001476 .

obo:VO_0017045 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0017031 , obo:VO_0017514 .

obo:VO_0001856 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0002436 , obo:VO_0007748 .

obo:VO_0004410 a rdfs:Class ;
  rdfs:label "Adjuvant arthritis DNA vaccine pcDNA-CCOL2A1 encoding type II collagen" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002823 .

obo:VO_0010054 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum Pfs48" ;
  rdfs:comment "A Pfs48 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0007740 a rdfs:Class ;
  rdfs:label "tumor lysate-pulsed dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine that is composed of dendritic cells pulsed with tumor cells lysates that stimulate a potent and specific cell mediated anti-tumor immune response. It can be used in combination with high-dose chemotherapy and hematopoietic stem cell transplantation (HSCT). The combination may increase overall survival and progression-free survival for patients with high-risk pediatric and young adult tumors (localized solid tumors such as, sarcoma, neuroblastoma, and Wilms' tumor). " ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0010946 a rdfs:Class ;
  rdfs:label "GNA2132" ;
  rdfs:comment "Protective antigen [PubMed: 10710308]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0004178 a rdfs:Class ;
  rdfs:label "AdH5-FluA NP vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:PATO_0002303 a rdfs:Class ;
  rdfs:label "decreased object quality" ;
  rdfs:comment "A quality of an object that has a value that is decreased compared to normal or average." ;
  rdfs:subClassOf obo:PATO_0000001 , obo:PATO_0001241 .

obo:VO_0021044 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0004527 a rdfs:Class ;
  rdfs:label "Eimeria maxima DNA vaccine pcDNA-Gam56" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001125 .

obo:VO_0001896 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002343 .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity"@en ;
  rdfs:comment "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:VO_0000028 a rdfs:Class ;
  rdfs:label "Comvax vaccine" ;
  rdfs:comment "Product Name: Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate) & Hepatitis B Vaccine (Recombinant)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000746 , obo:VO_0010437 , obo:VO_0010439 .

obo:VO_0003814 a rdfs:Class ;
  rdfs:label "FluMist Quadrivalent, 2016-2017 Formula Nasal Spray" ;
  rdfs:subClassOf obo:VO_0003807 .

obo:VO_0015648 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015584 , obo:VO_0015672 .

obo:VO_0018483 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018457 .

obo:VO_0004869 a rdfs:Class ;
  rdfs:label "HUMAN ADENOVIRUS E SEROTYPE 4 STRAIN CL-68578" ;
  rdfs:comment "RXAUI: 4624424" ;
  rdfs:subClassOf obo:NCBITaxon_10508 .

obo:VO_0018642 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injection [Je-Vax]" ;
  rdfs:subClassOf obo:VO_0000066 , obo:VO_0018640 .

obo:VO_0016732 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016718 .

obo:VO_0010834 a rdfs:Class ;
  rdfs:label "Herpes simplex virus type 1 and 2 protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0007715 a rdfs:Class ;
  rdfs:label "oral cancer vaccine V3-OVA" ;
  rdfs:comment "A cancer vaccine composed of autologous ovarian cancer antigens obtained from hydrolyzed, inactivated blood and tumor tissue of patients with ovarian cancer, with potential immunostimulatory and antineoplastic activities. The ovarian cancer antigens stimulate the immune system and activate a cytotoxic T-lymphocyte (CTL) immune response against ovarian cancer cells. Ovarian cancer patients can be given one pill a day for three months. " ;
  rdfs:subClassOf obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0002618 a rdfs:Class ;
  rdfs:label "obsolete asd from Salmonella spp." ;
  rdfs:comment "An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium" .

obo:VO_0007471 a rdfs:Class ;
  rdfs:label "obsolete Lymphoma DNA vaccine V_V_V_-FrC" ;
  rdfs:comment "Gene name: Fragment C from tetanus toxin" .

obo:VO_0019751 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2022 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020494 .

obo:VO_0003772 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003771 .

obo:VO_0011520 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus DNA vaccine encoding GatA/GatB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001085 .

obo:VO_0015608 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015557 , obo:VO_0015591 , obo:VO_0015655 .

obo:VO_0011278 a rdfs:Class ;
  rdfs:label "Gp63" ;
  rdfs:comment "Cell-mediated immunity to Leishmania major (L. major) was induced by injecting BALB/c mice intradermally with plasmid DNA expressing the conserved L. major cell surface glycoprotein gp63 (gp63-pcDNA-3).  Challenge studies revealed that gp63-pcDNA-3 vaccination protected 30% of susceptible mice (21 of 70) from Leishmania infection [PubMed: 9741428]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0015254 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Epaxal] Box of 1" ;
  rdfs:subClassOf obo:VO_0015253 , obo:VO_0015259 .

obo:VO_0001499 a rdfs:Class ;
  rdfs:label "VEE Virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against VEE Virus (Venezuelan equine encephalitis virus) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0017964 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML Prefilled Syringe [ActHIB] Box of 1" ;
  rdfs:subClassOf obo:VO_0017935 , obo:VO_0017948 .

obo:VO_0002603 a rdfs:Class ;
  rdfs:label "sodC from Francisella tularensis" ;
  rdfs:comment "A sodC mutant in Francisella tularensis subspecies holarctica was attenuated and provided protection and cleared the infection against lethal challenge in nearly 50% of the mice infected with the delta-sodC mutant." ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0004075 a rdfs:Class ;
  rdfs:label "PBT vaccine" ;
  rdfs:subClassOf obo:VO_0012187 .

obo:VO_0003653 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2018-2019 vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003652 .

obo:VO_0017752 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0017741 .

obo:VO_0007661 a rdfs:Class ;
  rdfs:label "GD2-CAR vaccine" ;
  rdfs:comment "A cancer vaccine made with T cells  genetically engineered to express anti-GD2 Chimeric Antigen Receptor to treat patients with children and young adults with GD2+ solid tumors, including neuroblastoma. The T cells may have an antitumor effect. They can be used in combination with AP1903 and Cyclophosphamide. (NCT02107963) There are increased CXCR3- classical monocytes in patients as CAR-T numbers waned." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0003928 a rdfs:Class ;
  rdfs:label "Fluad 2018-2019 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003913 .

obo:VO_0017094 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] Box of 5 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017093 .

obo:VO_0002641 a rdfs:Class ;
  rdfs:label "gyrA from Salmonella Typhimurium" ;
  rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0004315 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 DNA vaccine pRSVgIV" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000987 .

obo:UBERON_0000465 a rdfs:Class ;
  rdfs:label "material anatomical entity" ;
  rdfs:comment "Anatomical entity that has mass." ;
  rdfs:subClassOf obo:UBERON_0001062 .

obo:VO_0020346 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2022-2023 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 , obo:VO_0010428 .

obo:VO_0015503 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML [H B Vax]" ;
  rdfs:subClassOf obo:VO_0003257 .

obo:VO_0010166 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b vaccine, HbOC conjugate" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010437 .

obo:VO_0002365 a rdfs:Class ;
  rdfs:label "chicken bursal disease-Newcastle disease vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001222 , obo:VO_0001497 .

obo:VO_0002083 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.90)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0017945 a rdfs:Class ;
  rdfs:label "0.6 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017931 .

obo:VO_0007289 a rdfs:Class ;
  rdfs:label "Autologous Dendritic Cell-Tumor Fusion Vaccine" ;
  rdfs:comment "A therapeutic cancer vaccine consisting of autologous dendritic cells (DCs) fused with autologous tumor cells with potential immunostimulatory and antineoplastic activities. Autologous dendritic cell-tumor fusion vaccine is generated in vitro by mixing DCs and irradiated tumor cells harvested from individual patients and treating them with polyethylene glycol (PEG) to produce DC-tumor cell fusion hybrid cells. Upon administration, autologous dendritic cell-tumor fusion vaccine may elicit antitumor humoral and cellular immune responses." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0015110 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe" .

obo:VO_0001799 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome Reproductive & Respiratory Form, Modified Live Virus Vaccine (USDA: 19T1.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001511 , obo:VO_0007748 .

obo:VO_0019552 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020303 .

obo:VO_0004230 a rdfs:Class ;
  rdfs:label "Tetanus Toxoid vaccine with Calcium Phosphate" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000640 .

obo:VO_0019297 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluvirin 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020476 .

obo:VO_0007582 a rdfs:Class ;
  rdfs:label "Bacillus Calmette-Guerin (BCG) vaccine for melanoma" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0017079 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0017074 , obo:VO_0017121 , obo:VO_0017559 .

obo:VO_0018320 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabivac] Box of 1" ;
  rdfs:subClassOf obo:VO_0018291 , obo:VO_0018303 , obo:VO_0018323 .

obo:VO_0001484 a rdfs:Class ;
  rdfs:label "obsolete Caprine herpesvirus 1 vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Caprine herpesvirus 1" .

obo:VO_0001720 a rdfs:Class ;
  rdfs:label "Newcastle Disease VG/GA Strain, Live Virus Vaccine (USDA: 1701.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0005291 a rdfs:Class ;
  rdfs:label "Fos47 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:PATO_0001029 a rdfs:Class ;
  rdfs:label "efficiency" ;
  rdfs:comment "A physical quality inhering in a bearer by virtue of ratio of the bearer's output to the bearer's input." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:VO_0020031 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe [Agriflu 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020028 , obo:VO_0020307 .

obo:VO_0011000 a rdfs:Class ;
  rdfs:label "SAG1 from Toxoplasma gondii" ;
  rdfs:comment "Oral immunization of mice with ZJ111/pcDNA3-SAG1 elicited specific humoral responses and stimulated proliferation of splenocytes (P<0.05). Mice immunized with ZJ111/pcDNA3-SAG1 displayed significant protection against an intraperitoneally challenge with 500 tachyzoite forms of T. gondii RH strain. Vaccination at 10(7) and 10(8)CFU per mice provided a 20% and 10% survival rate comparing 100% mortality of the non-immunized mice, exhibiting longer living time and better survival rate [PubMed: 18590785]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0018220 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018249 .

obo:VO_0004629 a rdfs:Class ;
  rdfs:label "Leishmania tarentolae expressing HIV-1 Gag vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0020844 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Inflexal]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0010441 a rdfs:Class ;
  rdfs:label "licensed human measles virus vaccine" ;
  rdfs:comment "Measles virus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000654 .

obo:VO_0018855 a rdfs:Class ;
  rdfs:label "influenza A virus A/North Carolina/04/2016 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:VO_0011359 a rdfs:Class ;
  rdfs:label "Bordetella pertussis CyaA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0003951 a rdfs:Class ;
  rdfs:label "Ixiaro Injectable Product" ;
  rdfs:subClassOf obo:VO_0011558 .

obo:VO_0017874 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.005 MG" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0017031 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0017506 .

obo:VO_0015972 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 3" ;
  rdfs:subClassOf obo:VO_0003265 .

obo:VO_0019202 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019695 .

obo:VO_0019776 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML [Fluzone Quadrivalent 2021 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020492 .

obo:VO_0002550 a rdfs:Class ;
  rdfs:label "aroA from Aeromonas salmonicida" ;
  rdfs:comment "The aroA gene was inactivated by inserting a fragment expressing kanamycin resistance within the coding sequence and challenged in fish. The LD50 for unvaccinated fish was 71. In contrast, the LD50 was 1.8 x 104 in fish vaccinated once and 3 x 105 in fish vaccinated twice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001408 .

obo:VO_0017009 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0017007 .

obo:VO_0001082 a rdfs:Class ;
  rdfs:label "AcMNPV vector" ;
  rdfs:comment "an adenovirus vaccine vector that contains a deletion of the gp64 gene. As a result of the deletion, this vector is unable to propagate infection from cell to cell, and this defect results from both a severe reduction in the production of budded virions and the absence of GP64 on virions." ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0010365 a rdfs:Class ;
  rdfs:label "Zostavax (Frozen) vaccine" ;
  rdfs:subClassOf obo:VO_0000124 .

obo:VO_0016876 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 50 LFU/ML Injectable Solution by Aventis" ;
  rdfs:subClassOf obo:VO_0016763 .

obo:VO_0002994 a rdfs:Class ;
  rdfs:label "Simian Immunodeficiency Virus nef mutant vaccine" ;
  rdfs:comment "A SIV nef mutant is attenuated in rhesus monkeys and induces protection from challenge with wild type SIV" ;
  rdfs:subClassOf obo:VO_0000751 .

obo:NCBITaxon_169418 a rdfs:Class ;
  rdfs:label "Mustelinae" ;
  rdfs:subClassOf obo:NCBITaxon_3072906 .

obo:VO_0016202 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015902 .

obo:VO_0015487 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015499 .

obo:VO_0010371 a rdfs:Class ;
  rdfs:label "Pentacel MRC-5 vaccine" ;
  rdfs:subClassOf obo:VO_0000084 .

obo:VO_0020305 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2021-2022 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0001817 , obo:VO_0010423 .

obo:VO_0011165 a rdfs:Class ;
  rdfs:label "MDV095" ;
  rdfs:comment "Recombinant fowl poxviruses (rFPVs) were constructed to express genes from serotype 1 Marek's disease virus (MDV, Gallid herpesvirus 2). rFPV/gI expressing MDV095 conferred 43% protection in maternal antibody-positive chickens when challenged with highly virulent MDV isolates [PubMed: 14562881]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010804 .

obo:VO_0003841 a rdfs:Class ;
  rdfs:label "PEDIARIX vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003840 .

obo:VO_0010000 a rdfs:Class ;
  rdfs:label "Cp12 from Crptosporidium parvum" ;
  rdfs:comment "A Cp12 protein that is part of Crptosporidium parvum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010842 .

obo:VO_0019590 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019584 , obo:VO_0020493 .

obo:VO_0020541 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Afluria] Box of 10 by bioCSL" ;
  rdfs:subClassOf obo:VO_0020540 .

obo:VO_0004622 a rdfs:Class ;
  rdfs:label "fp-IBD1 vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001497 .

obo:VO_0020417 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 10" ;
  rdfs:subClassOf obo:VO_0020391 , obo:VO_0020427 .

obo:VO_0001811 a rdfs:Class ;
  rdfs:label "Transmissible Gastroenteritis Modified Live Virus Vaccine (USDA: 1961.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001505 , obo:VO_0007748 .

obo:VO_0004919 a rdfs:Class ;
  rdfs:label "vaccine specific Th1 immune response indicated by IgG2a  production" ;
  rdfs:comment "vaccine-induced T-helper 1 type immune response that is indicated by the presence of IgG2a production" ;
  rdfs:subClassOf obo:VO_0000100 .

obo:VO_0010785 a rdfs:Class ;
  rdfs:label "Mumps virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0018711 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015054 .

obo:VO_0000185 a rdfs:Class ;
  rdfs:label "Influenza virus gene" ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0016064 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015674 , obo:VO_0015788 .

obo:VO_0018845 a rdfs:Class ;
  rdfs:label "powder for oral suspension" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:VO_0018212 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 12500 UNT / Rubella virus vaccine 1000 UNT Injectable Suspension [M.M.R. VaxPro] by MSD" ;
  rdfs:subClassOf obo:VO_0018211 .

obo:VO_0018657 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0018653 .

obo:VO_0019213 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0016984 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 160 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017460 .

obo:VO_0020729 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020721 , obo:VO_0020737 .

obo:VO_0007018 a rdfs:Class ;
  rdfs:label "Recombinant Vaccinia-MUC-1 Vaccine" ;
  rdfs:comment "A vaccine containing a recombinant vaccinia virus that encodes the gene for human mucin-1, a tumor-associated antigen. Upon administration, recombinant vaccinia-MUC-1 vaccine may elicit a MUC-1-specific cytotoxic T cell response against tumor cells bearing MUC-1." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0016118 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015873 .

obo:VO_0019895 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Fluvirin 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019889 , obo:VO_0020477 .

obo:VO_0002430 a rdfs:Class ;
  rdfs:label "equine EEV and WEV encephalomyelitis-rhinopneumonitis-influenza-West Nile Virus vaccine-tetanus toxoid" ;
  rdfs:subClassOf obo:VO_0000752 , obo:VO_0002429 .

obo:VO_0002062 a rdfs:Class ;
  rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.F0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002385 , obo:VO_0007748 .

obo:VO_0004943 a rdfs:Class ;
  rdfs:label "human age 27 to 59 years at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004929 .

obo:VO_0000655 a rdfs:Class ;
  rdfs:label "licensed deer vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000363 .

obo:VO_0010080 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi TCTS-154" ;
  rdfs:comment "A TCTS-154 protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0002731 a rdfs:Class ;
  rdfs:label "NS1 from Influenza virus" ;
  rdfs:comment "Intranasal inoculation of mice, pigs, horses, and macaques with NS1-modified influenza virus strains induced robust humoral and cellular immune responses, and generated immune protection against challenge with wild-type virus" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000185 .

obo:VO_0001662 a rdfs:Class ;
  rdfs:label "Chicken Anemia Virus Modified Live Virus Vaccine (USDA: 10A1.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001510 , obo:VO_0007748 .

obo:VO_0001505 a rdfs:Class ;
  rdfs:label "Transmissible gastroenteritis virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Transmissible gastroenteritis virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0004897 .

obo:VO_0015831 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015626 .

obo:VO_0020186 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 667000 UNT/ML Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0020184 , obo:VO_0020185 , obo:VO_0020188 .

obo:VO_0017834 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Prefilled Syringe [Imuvac]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017888 .

obo:DOID_1205 a rdfs:Class ;
  rdfs:label "allergic disease"@en ;
  rdfs:comment "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods."@en ;
  rdfs:subClassOf obo:DOID_2914 .

obo:VO_0002737 a rdfs:Class ;
  rdfs:label "gp63 from Pseudorabies virus" ;
  rdfs:comment "A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky's disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001442 .

obo:VO_0003732 a rdfs:Class ;
  rdfs:label "Afluria 2017-2018 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003731 .

obo:VO_0004004 a rdfs:Class ;
  rdfs:label "BoNT/C vaccine" ;
  rdfs:subClassOf obo:VO_0012187 .

obo:VO_0015807 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0015494 .

obo:VO_0004395 a rdfs:Class ;
  rdfs:label "Brucella melitensis DNA vaccine pCIBLSOmp31 encoding BLSOmp31 (fusion protein)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000709 .

obo:VO_0016602 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0016588 , obo:VO_0016597 .

obo:VO_0002004 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica Toxoid (USDA: 4X49.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002369 .

obo:VO_0020755 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017681 .

obo:VO_0019505 a rdfs:Class ;
  rdfs:label "obsolete hepatitis A vaccine (inactivated) strain HM175 Injectable Suspension" .

obo:VO_0017889 a rdfs:Class ;
  rdfs:label "influenza B virus antigen, Hong Kong 330-2001 / meningococcal group C polysaccharide Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010444 , obo:VO_0017811 .

obo:VO_0001624 a rdfs:Class ;
  rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.12)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0005063 a rdfs:Class ;
  rdfs:label "pIRES1neo DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pIRES1neo.  This plasmid is 5257 base pairs in length and contains an ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0020783 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 ORGANISMS Injectable Suspension [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020781 , obo:VO_0020782 , obo:VO_0020807 .

obo:VO_0020710 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1920000000 CFU" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017679 .

obo:DOID_1100 a rdfs:Class ;
  rdfs:label "ovarian disease"@en ;
  rdfs:comment "A female reproductive system disease that is located_in the ovary."@en ;
  rdfs:subClassOf obo:DOID_229 , obo:DOID_28 .

obo:VO_0001717 a rdfs:Class ;
  rdfs:label "Newcastle Disease Killed Virus Vaccine (USDA: 1705.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001222 , obo:VO_0007748 .

obo:VO_0003298 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003333 .

obo:VO_0000859 a rdfs:Class ;
  rdfs:label "cell mediated correlated profile of immune protection" ;
  rdfs:comment "Correlated profile of immune protection that is reflected by a cell mediated immune response." ;
  rdfs:subClassOf obo:VO_0000857 .

obo:BFO_0000133 a rdf:Property ;
  rdfs:label "process profile of"@en ;
  rdfs:domain obo:BFO_0000144 ;
  rdfs:range obo:BFO_0000015 .

obo:VO_0007317 a rdfs:Class ;
  rdfs:label "ags-003-bld vaccine" ;
  rdfs:comment "A cancer vaccine composed of autologous, mature dendritic cells (DCs) are electroporated with in vitro transcribed (IVT) RNAs encoding for a synthetic form of T-cell protein CD40 ligand (CD40L) and IVT RNA encoding for autologous tumor-associated antigens (TAAs) derived from patient-specific bladder cell carcinoma (BCC) cells, with potential immunostimulatory and antineoplastic activities. The RNA is translated and processed, and BCC-specific antigenic peptides are subsequently presented via major histocompatibility complex (MHC) Class I molecules on the DCs surface. The MHC-presented peptides interact with and activate CD8-positive T-cells, which elicits a highly specific cytotoxic T-cell (CTL) response against tumor cells expressing the patient-specific BCC TAAs. The signal cascade initiated by expression of the co-stimulatory molecule CD40L results in the secretion of the inflammatory cytokine IL-12, which further stimulates CTLs. The vaccine can be used in combination with gemcitabine hydrochloride and cisplatin which stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading, while the vaccine helps the body build an effective immune response to kill tumor cells. In combination, they may make the tumor smaller and reduce the amount of tissue that needs to be removed by surgery in patients with bladder cancer." ;
  rdfs:subClassOf obo:VO_0005485 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0002941 a rdfs:Class ;
  rdfs:label "Yersinia pestis IpxM mutant vaccine" ;
  rdfs:comment "An IpxM mutant is attenuated in mice and guinea pigs. This mutant also conferred modest protection from challenge with wild type Y. pestis in Balb/c mice and significant protection in guinea pigs and outbred mice" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0019841 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003773 .

obo:VO_0016793 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Pediacel] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016731 .

obo:VO_0015910 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015626 , obo:VO_0015762 , obo:VO_0016021 .

obo:VO_0018776 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0017298 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017248 , obo:VO_0017297 .

obo:VO_0007719 a rdfs:Class ;
  rdfs:label "pancreatic tumor personalized neoantigen vaccine" ;
  rdfs:comment "A cancer vaccine based on next-generation sequencing and major histocompatibility complex affinity prediction algorithm, which may help treat patients with pancreatic ductal adenocarcinoma. This vaccine may elicit measurable neoantigen-specific immunologic responses in patients." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005430 , obo:VO_0007657 .

obo:VO_0020386 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution [Typhim V]" ;
  rdfs:subClassOf obo:VO_0020361 , obo:VO_0020368 , obo:VO_0020388 .

obo:NCIT_C85994 a rdfs:Class ;
  rdfs:label "Tuberculin Skin Test" ;
  rdfs:comment "A test to determine if a subject has ever had a tuberculosis infection. A small amount of purified tuberculosis protein is placed under the skin of the forearm and a positive skin reaction indicates previous exposure to Mycobacterium tuberculosis." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0000867 a rdfs:Class ;
  rdfs:label "Influvac vaccine" ;
  rdfs:comment "Influvac is an Influenza virus vaccine that is manufactured by Solvay Pharma." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0001176 , obo:VO_0010415 .

obo:VO_0019736 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0004462 a rdfs:Class ;
  rdfs:label "Schistosoma mansoni DNA vaccine pcDNA/CTSOD encoding SOD" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003046 .

obo:VO_0004831 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 1100000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 1400000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 1100000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 1000000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 1150000 UNT/ML [RotaTeq]" ;
  rdfs:subClassOf obo:VO_0000097 , obo:VO_0010448 .

obo:VO_0003375 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain Injectable Product" ;
  rdfs:subClassOf obo:VO_0003371 .

obo:VO_0000899 a rdfs:Class ;
  rdfs:label "obsolete dose" ;
  rdfs:comment "Dose is a measurement data that measures the quantity of something that may be eaten by or administered to an organism, or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses." .

obo:VO_0010849 a rdfs:Class ;
  rdfs:label "Rift Valley Fever virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0015619 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0003424 , obo:VO_0015549 .

obo:VO_0015937 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 3" ;
  rdfs:subClassOf obo:VO_0015636 , obo:VO_0016038 .

obo:VO_0012190 a rdfs:Class ;
  rdfs:label "Tick-borne Encephalitis Virus (TBEV) vaccine" ;
  rdfs:comment "A vaccine that protects against Tick-borne Encephalitis Virus (TBEV)." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003546 .

obo:VO_0004879 a rdfs:Class ;
  rdfs:label "Adenovirus Type 7 Vaccine Live Delayed Release Oral Tablet" ;
  rdfs:subClassOf obo:VO_0004878 .

obo:VO_0017893 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017813 .

obo:VO_0007657 a rdfs:Class ;
  rdfs:label "therapeutic cancer vaccine" ;
  rdfs:comment "Cancer vaccine that aims to eliminate or control tumor cells." ;
  rdfs:subClassOf obo:VO_0000177 , obo:VO_0000550 .

obo:VO_0002799 a rdfs:Class ;
  rdfs:label "Aeromonas hydrophila aroA mutant vaccine" ;
  rdfs:comment "An A. hydrophila aroA mutant is highly attenuated in trout, and a single immunization conferred significant protection from challenge with wild type A. hydrophila" ;
  rdfs:subClassOf obo:VO_0002505 .

obo:VO_0001973 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1189.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0002698 a rdfs:Class ;
  rdfs:label "aroA from Yersinia ruckeri" ;
  rdfs:comment "An aroA mutant is highly attenuated in rainbow trout and induces significant protection from challenge with wild type Y. ruckeri" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001428 .

obo:VO_0016300 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 20 by Merck" ;
  rdfs:subClassOf obo:VO_0016029 .

obo:VO_0017313 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / pertactin adsorbed 0.005 MG/ML / Pertussis Vaccine 0.016 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017301 , obo:VO_0017312 .

obo:VO_0003073 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0000714 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0020529 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0020524 , obo:VO_0020884 .

obo:DOID_74 a rdfs:Class ;
  rdfs:label "hematopoietic system disease"@en ;
  rdfs:comment "A disease of anatomical entity that has_material_basis_in hematopoietic cells."@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:VO_0015153 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0001354 a rdfs:Class ;
  rdfs:label "combination vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is composed of differnt compounds under more than one category." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017371 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxin Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0001494 a rdfs:Class ;
  rdfs:label "Porcine parvovirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Porcine parvovirus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0015794 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015492 .

obo:VO_0010155 a rdfs:Class ;
  rdfs:label "hepatitis B vaccine, dialysis patient dosage" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010439 .

obo:VO_0018003 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003213 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0019954 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Afluria 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019952 , obo:VO_0020302 .

obo:VO_0002897 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium IppB/msbB mutant vaccine" ;
  rdfs:comment "An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0003353 a rdfs:Class ;
  rdfs:label "Vivotif vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000671 , obo:VO_0000714 , obo:VO_0001217 , obo:VO_0010451 .

obo:IAO_0000009 a rdfs:Class ;
  rdfs:label "datum label"@en ;
  rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0004708 a rdfs:Class ;
  rdfs:label "Maraba virus MG1 vaccine" ;
  rdfs:comment "Gene name: MUC5B" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0016097 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015992 .

obo:VO_0010148 a rdfs:Class ;
  rdfs:label "Anthrax vaccine, adsorbed, adjuvanted, post-exposure prophylaxis" ;
  rdfs:subClassOf obo:VO_0000014 .

obo:VO_0001087 a rdfs:Class ;
  rdfs:label "human adenovirus vaccine vector" ;
  rdfs:comment "an adenovirus vaccine vector that uses a human adenovirus as the vector strain." ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0018549 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018545 .

obo:VO_0003033 a rdfs:Class ;
  rdfs:label "bovine serum albumin vaccine additive" ;
  rdfs:comment "a protein vaccine stablizer that is specifically bovine serum albumin. " ;
  rdfs:subClassOf obo:VO_0003038 .

obo:VO_0015200 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015205 , obo:VO_0015281 .

obo:VO_0002354 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0000568 , obo:VO_0002338 , obo:VO_0002352 .

obo:VO_0016061 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015671 , obo:VO_0015817 .

obo:VO_0004681 a rdfs:Class ;
  rdfs:label "rNDV-H5 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0019195 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019194 , obo:VO_0019671 .

obo:VO_0007407 a rdfs:Class ;
  rdfs:label "live-attenuated double-deleted listeria monocytogenes bacteria JNJ-64041809 vaccine" ;
  rdfs:comment "A proprietary, live-attenuated, double-deleted (LADD) strain of the Gram-positive bacterium Listeria monocytogenes (Lm) encoding multiple, as of yet undisclosed, tumor-associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, live-attenuated double-deleted Listeria monocytogenes bacteria JNJ-64041809 is taken up by antigen-presenting cells (APCs), including dendritic cells (DCs). The TAAs are subsequently expressed by the APCs and then processed and presented to the immune system by both major histocompatibility complex (MHC) class I and II molecules. This activates the immune system and leads to the recruitment and activation of cytotoxic T-lymphocytes (CTLs) against the TAA-expressing tumor cells, eventually resulting in tumor cell lysis. Two genes contributing to the virulence of Lm have been removed to minimize the risk of infection." ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0007657 .

obo:VO_0007349 a rdfs:Class ;
  rdfs:label "CAP-2 (CEA peptide 9-mer) vaccine" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0007047 a rdfs:Class ;
  rdfs:label "TARP 27-35 peptide vaccine" ;
  rdfs:comment "A peptide-based cancer vaccine, containing amino acid residues 27 through 35 of T cell receptor gamma alternate reading frame protein (TARP), with potential immunostimulatory and antineoplastic activities. Upon administration, TARP 27-35 peptide vaccine may stimulate a host cytotoxic T-cell (CTL) response against TARP-expressing tumor cells, resulting in tumor cell cytotoxicity. The nuclear protein TARP is commonly expressed on prostate and breast cancer cells and is highly immunogenic." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0010274 a rdfs:Class ;
  rdfs:label "assay mesurement datum" ;
  rdfs:comment "A measurment datum that records the measurement of an assay." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0004343 a rdfs:Class ;
  rdfs:label "SIV DNA vaccine pVacc4 encoding env from mac239" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000751 .

obo:VO_0019131 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010433 .

obo:VO_0018368 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003344 .

obo:VO_0018450 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML Injectable Solution [Pneumovax 23] by Merck" ;
  rdfs:subClassOf obo:VO_0018429 .

obo:NCBITaxon_83558 a rdfs:Class ;
  rdfs:label "Chlamydia pneumoniae" ;
  rdfs:subClassOf obo:NCBITaxon_810 .

obo:VO_0018051 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 17500 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018050 , obo:VO_0018140 .

obo:VO_0003610 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2013-2014 Formula Influenza Virus Vaccine 0.25 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003609 .

obo:VO_0004182 a rdfs:Class ;
  rdfs:label "Salmonella typhi DnaJ protein vaccine" ;
  rdfs:subClassOf obo:VO_0000671 .

obo:VO_0004880 a rdfs:Class ;
  rdfs:label "Adenovirus Type 7 Vaccine Live 32000 UNT Delayed Release Oral Tablet" ;
  rdfs:subClassOf obo:VO_0004879 .

obo:VO_0017393 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Adt Booster]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0018791 .

obo:VO_0003438 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 2000000000 UNT" ;
  rdfs:subClassOf obo:VO_0003446 .

obo:VO_0000707 a rdfs:Class ;
  rdfs:label "primary vaccination" ;
  rdfs:comment "A vaccination process that occurs at the first time to a host organization in a specified period." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:MONDO_0005194 a rdfs:Class ;
  rdfs:label "Rotavirus infection" ;
  rdfs:comment "Infection with any of the rotaviruses. Specific infections include human infantile diarrhea, neonatal calf diarrhea, and epidemic diarrhea of infant mice." ;
  rdfs:subClassOf obo:DOID_0050117 .

obo:VO_0000466 a rdfs:Class ;
  rdfs:label "soybean-expressed E. coli LTB vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:NCBITaxon_391902 a rdfs:Class ;
  rdfs:label "Bubalus bubalis bubalis" ;
  rdfs:subClassOf obo:NCBITaxon_27592 .

obo:VO_0004332 a rdfs:Class ;
  rdfs:label "Human papillomavirus DNA vaccine E7IR" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000667 .

obo:VO_0017634 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017632 , obo:VO_0017637 .

obo:VO_0007032 a rdfs:Class ;
  rdfs:label "PCLUS 3-18MN vaccine" ;
  rdfs:comment "A synthetic HIV-1 envelope peptide that was developed for use as a vaccine. Vaccination with PCLUS 3-18MN may stimulate the host immune system to mount cytotoxic T lymphocyte (CTL) and T helper cell responses, and induce the production of neutralizing antibodies." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0016136 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0017110 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur] Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0017109 .

obo:VO_0017091 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] Box of 20" ;
  rdfs:subClassOf obo:VO_0017088 , obo:VO_0017118 , obo:VO_0017565 .

obo:NCBITaxon_36362 a rdfs:Class ;
  rdfs:label "Polyomavirus sp." ;
  rdfs:subClassOf obo:NCBITaxon_151341 .

obo:VO_0003873 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML / Hepatitis B Surface Antigen Vaccine 0.01 MG/ML [COMVAX]" ;
  rdfs:subClassOf obo:VO_0000028 , obo:VO_0000195 .

obo:DOID_0080355 a rdfs:Class ;
  rdfs:label "hepatobiliary system cancer"@en ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the hepatobiliary system."@en ;
  rdfs:subClassOf obo:DOID_3119 .

obo:VO_0002491 a rdfs:Class ;
  rdfs:label "Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Modified Live Virus & Avirulent Live Culture Vaccine (USDA: 12X1.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002386 , obo:VO_0007748 .

obo:VO_0001037 a rdfs:Class ;
  rdfs:label "Bordetella pertussis BPZE vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector using a live attenuated Bordetella pertussis BPZE as a vaccine vector." ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0011137 a rdfs:Class ;
  rdfs:label "NP from Influenza A virus (A/chicken/Hubei/489/2004(H5N1))" ;
  rdfs:comment "Vaccination with ptPAs/NP derived from Influenza A virus (A/chicken/Hubei/489/2004(H5N1)) efficiently cleared the homologous H5N1 influenza virus in the infected lungs and induced partial cross-protection against heterologous, highly pathogenic H5N1 strains in mice [PubMed: 18789973]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0016973 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 50 LFU/ML / tetanus toxin 10 LFU/ML Injectable Solution by Aventis" ;
  rdfs:subClassOf obo:VO_0016972 .

obo:VO_0015623 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015662 .

obo:NCBITaxon_5807 a rdfs:Class ;
  rdfs:label "Cryptosporidium parvum" ;
  rdfs:subClassOf obo:NCBITaxon_423054 .

obo:VO_0019452 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0000983 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0020310 a rdfs:Class ;
  rdfs:label "Fluad 2020-2021 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0004281 , obo:VO_0010424 .

obo:VO_0001172 a rdfs:Class ;
  rdfs:label "pCIOmp31 vaccine" ;
  rdfs:comment "pCIOmp31 is a B. melitensis DNA vaccine expressing Omp31 that uses the pCI plasmid." ;
  rdfs:subClassOf obo:VO_0000325 .

obo:VO_0021028 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003279 , obo:VO_0021047 .

obo:VO_0001758 a rdfs:Class ;
  rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012180 .

obo:VO_0017165 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0017164 .

obo:NCBITaxon_42890 a rdfs:Class ;
  rdfs:label "Sarcocystis neurona" ;
  rdfs:subClassOf obo:NCBITaxon_5809 .

obo:VO_0017813 a rdfs:Class ;
  rdfs:label "Meningococcal Polysaccharide Vaccine, Groups A & C" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0003206 a rdfs:Class ;
  rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML" ;
  rdfs:subClassOf obo:VO_0003200 .

obo:VO_0010101 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii hsp70" ;
  rdfs:comment "A hsp70 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0010726 a rdfs:Class ;
  rdfs:label "Menjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010444 .

obo:VO_0000864 a rdfs:Class ;
  rdfs:label "Canada licensed vaccine role" ;
  rdfs:comment "a licensed status that occurs in Canada." ;
  rdfs:subClassOf obo:VO_0000630 .

obo:VO_0019429 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Decavac]" ;
  rdfs:subClassOf obo:VO_0000030 , obo:VO_0017670 .

obo:VO_0001291 a rdfs:Class ;
  rdfs:label "DOC/Alum Complex vaccine adjuvant" ;
  rdfs:comment "A mineral salt vaccine adjuvant that is composed of Deoxycholic acid sodium salt (DOC) complexed with aluminum hydroxide." ;
  rdfs:subClassOf obo:VO_0000093 .

obo:NCBITaxon_694002 a rdfs:Class ;
  rdfs:label "Betacoronavirus" ;
  rdfs:subClassOf obo:NCBITaxon_2501931 .

obo:VO_0007267 a rdfs:Class ;
  rdfs:label "anti-NY-ESO1 TCR-transduced Autologous CD62L+-derived T-Lymphocytes vaccine" ;
  rdfs:comment "Human autologous CD62L-positive T-lymphocytes transduced with a retroviral vector encoding a T cell receptor (TCR) specific for the cancer-testis antigen NY-ESO-1, with potential antineoplastic activity. Following leukapheresis, isolation of lymphocytes, expansion ex vivo, transduction, and reintroduction into the patient, the anti-NY-ESO1 TCR-transduced autologous CD62L+-derived T-Lymphocytes bind to NY-ESO-1-overexpressing tumor cells. This may result in cytotoxic T-lymphocyte (CTL)-mediated elimination of NY-ESO-1-positive cancer cells. NY-ESO-1, a tumor associated antigen (TAA), is found in normal testis and on the surface of various tumor cell types. CD62L, also called L-selectin, is a lymphoid homing receptor and differentiation marker and is expressed on a subset of CD8-positive T-lymphocytes; it is involved in the migration of T-lymphocytes to lymph nodes and may improve the efficacy for ex vivo-expanded T-cells following adoptive cell therapy." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0018722 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1" ;
  rdfs:subClassOf obo:VO_0018721 , obo:VO_0018723 .

obo:VO_0018804 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000667 .

obo:VO_0000145 a rdfs:Class ;
  rdfs:label "recombinant vaccine vector role" ;
  rdfs:comment "A vaccine vector role that inheres in a recombinant vaccine vector as a vaccine component. The combination of a recombinant vaccine vector and a heterogenous protective antigen(s) inserted inside the vector for a recombinant vector vaccine. " ;
  rdfs:subClassOf obo:VO_0003439 .

obo:VO_0018397 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe [Synflorix]" ;
  rdfs:subClassOf obo:VO_0001245 , obo:VO_0018517 .

obo:VO_0010975 a rdfs:Class ;
  rdfs:label "GNA1220" ;
  rdfs:comment "Protective antigen [PubMed: 10710308]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0020772 a rdfs:Class ;
  rdfs:label "BCG, live, Tice strain 12.5 MG Injection [OncoTICE] by Schering-Plough" ;
  rdfs:subClassOf obo:VO_0020769 .

obo:VO_0015820 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015598 .

obo:VO_0021160 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0018410 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 4 vaccine 0.006 MG/ML" ;
  rdfs:subClassOf obo:VO_0003232 .

obo:VO_0004358 a rdfs:Class ;
  rdfs:label "Hepatitis B DNA vaccine pCMV-HBs encoding HBsAg" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000644 .

obo:VO_0011454 a rdfs:Class ;
  rdfs:label "Dengue DNA vaccine encoding NS1 protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0021122 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hawaii/70/2019 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Minnesota/41/2019 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020325 .

obo:VO_0015259 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015252 .

obo:VO_0019971 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML [Afluria 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020300 .

obo:VO_0007170 a rdfs:Class ;
  rdfs:label "UV1 Telomerase Peptide Vaccine" ;
  rdfs:comment "A synthetic, peptide cancer vaccine directed against the human telomerase reverse transcriptase catalytic subunit (hTERT) with potential immunomodulating activity. Vaccination with the UV1 telomerase peptide may stimulate cytotoxic T-cells to recognize and kill telomerase-expressing cells. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0017209 a rdfs:Class ;
  rdfs:label "1 ML tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution [Tetabulin] by Baxter" ;
  rdfs:subClassOf obo:VO_0017206 .

obo:VO_0020790 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 500000000 CFU Injection" ;
  rdfs:subClassOf obo:VO_0019412 , obo:VO_0020788 .

obo:VO_0000560 a rdfs:Class ;
  rdfs:label "toxin" ;
  rdfs:comment "A toxin is a poisonous substance produced within living cells or organisms; man-made substances created by artificial processes are thus excluded. " ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0015069 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0003977 a rdfs:Class ;
  rdfs:label "KINRIX vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003974 .

obo:VO_0000837 a rdfs:Class ;
  rdfs:label "microencapsulated Caf1 and LcrV vaccine" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0017763 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution [Tussoglobin]" ;
  rdfs:subClassOf obo:VO_0017761 , obo:VO_0017762 , obo:VO_0017769 .

obo:VO_0010953 a rdfs:Class ;
  rdfs:label "PepA" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0002694 a rdfs:Class ;
  rdfs:label "smpB from Yersinia pestis" ;
  rdfs:comment "An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001426 .

obo:VO_0010468 a rdfs:Class ;
  rdfs:label "correlated profile of immune protection based on statistical level" ;
  rdfs:subClassOf obo:VO_0000857 .

obo:VO_0002719 a rdfs:Class ;
  rdfs:label "HBVgp3 X protein from Hepatitis B virus" ;
  rdfs:comment "Researchers generated a series of woodchuck hepatitis virus (WHV) X mutants. Woodchucks inoculated with X mutants, including those with no serologic evidence of infection, were protected from later challenge with infectious Woodchuck Hepatitis Virus, suggesting previous infection with resulting protective immunity" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001436 .

obo:VO_0020686 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0020683 .

obo:VO_0007263 a rdfs:Class ;
  rdfs:label "anti-Idiotype specified monoclonal antibody vaccine" ;
  rdfs:comment "A synthetic antibody produced by a genetically homogenous population of hybrid cells (hybridoma) against determinant idiotypes (Id) which usually mimic human epitopes. Anti-Id vaccines may be effective in the treatment of B-cell lymphomas, resulting in tumor regression. Anti-idiotype vaccine therapy is less likely to induce autoimmunity if the target antigen is not normally expressed on normal tissues. Monoclonal antibodies have become powerful tools for tumor targeting, recognizing different protein markers on certain cancer cells and may be used alone or as delivery agents for drugs, toxins or radioactive material targeted to tumors." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0004022 a rdfs:Class ;
  rdfs:label "Leishmania donovani GRP-78 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001142 .

obo:VO_0001098 a rdfs:Class ;
  rdfs:label "persons living with or providing care for infants aged <6 months" ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:VO_0015825 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015620 .

obo:VO_0019806 a rdfs:Class ;
  rdfs:label "influenza A virus A/Idaho/07/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Indiana/08/2018 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0000956 a rdfs:Class ;
  rdfs:label "Brucella abortus conjugate vaccine" ;
  rdfs:comment "a B. abortus vaccine that uses a conjugate vaccine format" ;
  rdfs:subClassOf obo:VO_0000108 , obo:VO_0000195 .

obo:VO_0004052 a rdfs:Class ;
  rdfs:label "Streptococcus agalactiae Sip protein vaccine" ;
  rdfs:subClassOf obo:VO_0001375 .

obo:VO_0018631 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 12 BAU/ML" ;
  rdfs:subClassOf obo:VO_0003948 .

obo:VO_0010928 a rdfs:Class ;
  rdfs:label "B. abortus strain 19 L7/L12" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0010349 a rdfs:Class ;
  rdfs:label "Influenza A (H1N1) 2009 Monovalent Vaccine (ID Biomedical Corporation of Quebec)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0010415 .

obo:VO_0019630 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2016 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020488 .

obo:VO_0003035 a rdfs:Class ;
  rdfs:label "amino acid vaccine stabilizer" ;
  rdfs:comment "a vaccine stabilizer that is generated based on amino acids. " ;
  rdfs:subClassOf obo:VO_0000853 .

obo:VO_0010428 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2022-2023" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0002292 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4975.01)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002462 , obo:VO_0007748 .

obo:VO_0005254 a rdfs:Class ;
  rdfs:label "SC-Ad6-1 vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant adenoviral vector vaccine by Tetherex Pharmaceutical Corporation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:VO_0011320 a rdfs:Class ;
  rdfs:label "S protein of SARS-CoV" ;
  rdfs:comment "The receptor-binding domain (RBD) of SARS-CoV spike (S) protein is an important target in developing safe and effective SARS vaccines. A previous study has demonstrated that vaccination with adeno-associated virus encoding RBD (RBD-rAAV) induces high titer of neutralizing antibodies. The immune responses and protective effect of the immunization with RBD-rAAV prime/RBD-specific T cell peptide boost were assessed. Compared with the RBD-rAAV prime/boost vaccination, RBD-rAAV prime/RBD-peptide (RBD-Pep) boost induced similar levels of Th1 and neutralizing antibody responses that protected the vaccinated mice from subsequent SARS-CoV challenge, but stronger Th2 and CTL responses. No significant immune responses and protective effects were detected in mice vaccinated with RBD-Pep or blank AAV alone [PubMed: 18289745]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010850 .

obo:VO_0000613 a rdfs:Class ;
  rdfs:label "male biological sex datum" ;
  rdfs:comment "A biological sex datum that represents the biological sex of an animal (including human) as being male." ;
  rdfs:subClassOf obo:VO_0001194 .

obo:IAO_0000136 a rdf:Property ;
  rdfs:label "is about"@en ;
  rdfs:comment "A (currently) primitive relation that relates an information artifact to an entity."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0007549 a rdfs:Class ;
  rdfs:label "GM2/GD2/GD3 Lactone-KLH conjugate trivalent vaccine" ;
  rdfs:comment "A trivalent cancer vaccine containing the ganglioside lactones GM2, GD2 and GD3 conjugated with the immunostimulant keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with GM2 lactone/GD2 lactone/GD3 lactone-KLH conjugate trivalent vaccine may elicit antibodies against tumor cells expressing any of these epitopes, resulting in an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing these gangliosides. GM2, GD2 and GD3 are tumor associated antigens (TAAs) that are overexpressed in a variety of tumor cell membranes." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0007657 .

obo:NCBITaxon_94063 a rdfs:Class ;
  rdfs:label "Leptospira sp. Pomona" ;
  rdfs:subClassOf obo:NCBITaxon_171 .

obo:VO_0016507 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:NCBITaxon_11047 a rdfs:Class ;
  rdfs:label "Equine arteritis virus" ;
  rdfs:subClassOf obo:NCBITaxon_76803 .

obo:VO_0004670 a rdfs:Class ;
  rdfs:label "S. gordonii-PT vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0016938 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 25 LFU/ML / Pertussis Vaccine 8 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017401 .

obo:VO_0019184 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0020320 .

obo:VO_0000448 a rdfs:Class ;
  rdfs:label "Salmonella paratyphi vaccine" ;
  rdfs:comment "a Salmonella vaccine against infection with S. paratyphi, which causes paratyphoid fevers. Paratyphoid fevers are a group of enteric illnesses caused by serotypic strains of the Salmonella genus of bacteria, S. Paratyphi." ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0016578 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000745 , obo:VO_0001214 .

obo:VO_0015645 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Lt Grk]" ;
  rdfs:subClassOf obo:VO_0003420 , obo:VO_0015553 .

obo:VO_0003637 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016-2017 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003634 .

obo:BFO_0000145 a rdfs:Class ;
  rdfs:label "relational quality"@en ;
  rdfs:comment "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:VO_0007618 a rdfs:Class ;
  rdfs:label "HUVECs-OK432 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0002051 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Standard & Variant, Serotype 3, Live Virus Vaccine (USDA: 12C8.40)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0011281 a rdfs:Class ;
  rdfs:label "Cpb" ;
  rdfs:comment "Together with poloxamer 407 as adjuvant the recombinant type I (rCPB) cysteine proteinase of Leishmania major was screened as a potential vaccines against L. major in a mouse model.  Using the footpad thickness increase to monitor the clinical outcome/cutaneous lesion at site of L. major delivery, it was possible to document that rCPB allowed BALB/c mice to mount a partial protective response [PubMed: 12057598]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:NCBITaxon_9005 a rdfs:Class ;
  rdfs:label "Phasianidae" ;
  rdfs:subClassOf obo:NCBITaxon_1549675 .

obo:VO_0015634 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [H-B-Vax II]" ;
  rdfs:subClassOf obo:VO_0003426 , obo:VO_0015568 .

obo:NCBITaxon_632 a rdfs:Class ;
  rdfs:label "Yersinia pestis" ;
  rdfs:subClassOf obo:NCBITaxon_1649845 .

obo:VO_0019441 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 13.4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018786 .

obo:VO_0007278 a rdfs:Class ;
  rdfs:label "Autologous CD133-Positive BTSC mRNA-Pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous dendritic cells (DCs) loaded with CD133-positive autologous brain tumor stem cells (BTSCs) -derived mRNA with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, autologous CD133-positive BTSC mRNA-pulsed autologous dendritic cell vaccine may elicit a cytotoxic T-lymphocyte (CTL) response against the CD133-positive BTSCs from which the autologous tumor mRNA is derived. CD133, a tumor-associated antigen (TAA) and neural stem cell marker, has been found on a specific subset of glioblastoma multiforme (GBM) stem cells; its presence has been correlated with resistance to conventional chemotherapy and radiotherapy." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0007036 a rdfs:Class ;
  rdfs:label "recombinant Fowlpox-B7.1 vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the stimulatory molecule transgene B7-1. Recombinant fowlpox-B7.1 (rF-B7.1) vaccine may enhance antigen presentation and activate antitumoral cytotoxic T-cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0017562 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Covaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0017561 , obo:VO_0017576 .

obo:OPL_0000232 a rdfs:Class ;
  rdfs:label "parasite organism" ;
  rdfs:comment "An organism living in, with, or on another organism in parasitism. Individual members of parasite species, such as Leishmania, Plasmodium, Trypanosoma, etc. are members of this class." ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:VO_0017802 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML" ;
  rdfs:subClassOf obo:VO_0003196 .

obo:VO_0019173 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.005 MG/ML / meningococcal group C polysaccharide 0.01 MG/ML / meningococcal polysaccharide vaccine group Y 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0019489 .

obo:VO_0005200 a rdfs:Class ;
  rdfs:label "COVID-19 recombinant adenoviral vector vaccine" ;
  rdfs:subClassOf obo:VO_0005199 .

obo:VO_0016589 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016584 .

obo:VO_0005096 a rdfs:Class ;
  rdfs:label "S-268019 vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant protein vaccine¬¨‚Ä†that uses the Baculovirus expression vector system." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0001026 a rdfs:Class ;
  rdfs:label "AquaVac Furuvac vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000645 , obo:VO_0000820 .

obo:VO_0001781 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis Killed Virus Vaccine (USDA: 1525.24)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001486 , obo:VO_0007748 .

obo:VO_0002139 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.29)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002395 , obo:VO_0007748 .

obo:VO_0015656 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0015559 , obo:VO_0015602 .

obo:VO_0016761 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0019451 .

obo:VO_0016083 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Mtk" ;
  rdfs:subClassOf obo:VO_0015869 .

obo:VO_0007447 a rdfs:Class ;
  rdfs:label "human papillomavirus  18 L1-VLP vaccine" ;
  rdfs:comment "Noninfectious, synthetic, virus-like particles (VLP) containing the major viral capsid protein, L1, of the human papillomavirus type 18 with potential immunoprotective activity. Vaccination with HPV 18 L1-VLP may stimulate the host immune system to mount cytotoxic T lymphocyte (CTL) response against cells positive for HPV 18, thereby preventing cervical infection upon exposure to HPV type 18." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0019124 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0020305 .

obo:VO_0012402 a rdfs:Class ;
  rdfs:label "Sip" ;
  rdfs:comment "Immunization with the recombinant Sip protein efficiently protected CD-1 mice against deadly challenges with six GBS strains of serotypes Ia/c, Ib, II/R, III, V, and VI [PubMed: 10992461]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012356 .

obo:VO_0001521 a rdfs:Class ;
  rdfs:label "Edwardsiella ictaluri vaccine" ;
  rdfs:comment "An Edwardsiella bacterial vaccine that is used to protect against Edwardsiella ictaluri infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000602 .

obo:VO_0002102 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0019678 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML / influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML Prefilled Syringe [FLUAD 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003910 , obo:VO_0010427 , obo:VO_0019677 .

obo:VO_0017357 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Tri-Immunol Im]" ;
  rdfs:subClassOf obo:VO_0017349 .

obo:VO_0018768 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003500 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0005309 a rdfs:Class ;
  rdfs:label "Th1-biased immune profile" ;
  rdfs:comment "An immune profile that is characterized by the presence of Type 1 T helper (Th1) cells that produce interferon-gamma, interleukin (IL)-2, and tumor necrosis factor (TNF)-beta, which activate macrophages and are responsible for cell-mediated immunity and phagocyte-dependent protective responses." ;
  rdfs:subClassOf obo:VO_0005308 .

obo:VO_0019292 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Afluria 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020302 .

obo:VO_0001043 a rdfs:Class ;
  rdfs:label "canarypox vaccine vector" ;
  rdfs:comment "an Avipox virus vaccine vector that uses an attenuated canarypox virus strain" ;
  rdfs:subClassOf obo:VO_0001143 .

obo:VO_0002250 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.24)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002422 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0010760 a rdfs:Class ;
  rdfs:label "Francisella tularensis protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0011019 a rdfs:Class ;
  rdfs:label "ApxIA" ;
  rdfs:comment "The ApxI antigen is an important factor in the protection against Actinobacillus pleuropneumoniae serotype 5 infection; therefore, the protective immunity in mice following oral immunization with Saccharomyces cerevisiae expressing either ApxIA (group C) or ApxIIA (group D) alone or both (group E) was compared with that in two control groups (group A and B). The immunogenicity of the rApxIA antigen derived from the yeast was confirmed by a high survival rate and an ApxIA-specific IgG antibody response (p < 0.01) [PubMed: 17993753]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010821 .

obo:VO_0016888 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0016880 .

obo:VO_0004858 a rdfs:Class ;
  rdfs:label "smallpox vaccine live vaccinia virus 500000000 UNT/ML [ACAM2000]" ;
  rdfs:subClassOf obo:VO_0000003 .

obo:VO_0020176 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injection [RabAvert]" ;
  rdfs:subClassOf obo:VO_0000094 , obo:VO_0020175 .

obo:PR_000001155 a rdfs:Class ;
  rdfs:label "Toll-like receptor 4" ;
  rdfs:comment "A Toll-like receptor that is a translation product of the human TLR4 gene or a 1:1 ortholog thereof." ;
  rdfs:subClassOf obo:PR_000001096 .

obo:VO_0020869 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Influsplit]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020896 .

obo:VO_0003334 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0004189 a rdfs:Class ;
  rdfs:label "Pseudomonas aeruginosa DNA vaccine encoding OprF" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000393 .

obo:IAO_8000014 a rdfs:Class ;
  rdfs:label "generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:VO_0003024 a rdfs:Class ;
  rdfs:label "lyophilized vaccine powder" ;
  rdfs:comment "a vaccine powder that is freeze-dried and lyophilized. " ;
  rdfs:subClassOf obo:VO_0000228 .

obo:VO_0002753 a rdfs:Class ;
  rdfs:label "PE2 from Western equine encephalomyelitis virus" ;
  rdfs:comment "A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001449 .

obo:VO_0017640 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [Clostet]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0018181 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain Injectable Solution [Mmr Priorix]" ;
  rdfs:subClassOf obo:VO_0018179 .

obo:VO_0004797 a rdfs:Class ;
  rdfs:label "ChAd63 -PvTRAP vaccine" ;
  rdfs:subClassOf obo:VO_0000758 .

obo:VO_0007534 a rdfs:Class ;
  rdfs:label "ESO-1:157-165(165V) peptide vaccine" ;
  rdfs:comment "A 9-residued peptide vaccine consisting of amino acids 157 through 165 of the cancer/testis (CT) antigen ESO-1. Modified at position 165 (cysteine to valine) to improve immunogenicity, ESO-1:157-165(165v) peptide administered as a vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for ESO-1, resulting in decreased tumor growth. ESO-1 is expressed in a variety of cancers, including melanoma, breast, bladder, prostate, and hepatocellular cancers." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0005425 , obo:VO_0005484 , obo:VO_0005485 , obo:VO_0005499 , obo:VO_0007657 .

obo:VO_0007704 a rdfs:Class ;
  rdfs:label "mutated neopeptide vaccine" ;
  rdfs:comment "A cancer vaccine with neopeptides designed with single amino acid mutations to enhance their immunogenicity and bind to HLA class I and II molecules. Exome and RNA sequencing as well as in silico HLA-binding predictions to autologous HLA molecules were used to identify candidate neopeptides. Subsequently, in silico HLA-anchor placements were used to deduce putative T-cell receptor (TCR) contacts of peptides. Single amino acids of TCR contacting residues were then mutated by amino acid replacements. TIL-derived CD4+ T-cell clones showed strong responses and tumor cell lysis not only against the designed neopeptide but also against the unmutated natural peptides of the tumor. Turning tumor self-peptides into foreign antigens by introduction of designed mutations is a promising strategy to induce strong intratumoral CD4+ T-cell responses in a cold tumor like glioblastoma." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0010704 a rdfs:Class ;
  rdfs:label "review of vaccine license application" ;
  rdfs:comment "A vaccine regulatory process that is for vaccine regulatory agent to review vaccine license application from vaccine producer." ;
  rdfs:subClassOf obo:VO_0000683 .

obo:VO_0020988 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigens, strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain Nib-88" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010303 , obo:VO_0010415 .

obo:VO_0001311 a rdfs:Class ;
  rdfs:label "Rehydragel HPA vaccine adjuvant" ;
  rdfs:comment "An aluminum vaccine adjuvant that is a synthetic oxyhydroxide of aluminum (aluminum hydroxide) prepared by acid-base precipitation." ;
  rdfs:subClassOf obo:VO_0000884 .

obo:VO_0020940 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0003507 , obo:VO_0004914 .

obo:VO_0007223 a rdfs:Class ;
  rdfs:label "Allogeneic GM-CSF-Based Myeloma Cell Vaccine" ;
  rdfs:comment "An allogeneic tumor cell vaccine containing myeloma cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Upon vaccination, allogeneic GM-CSF-based myeloma cellular vaccine secretes GM-CSF, which may potentiate a tumor-specific cytotoxic T-lymphocyte (CTL) response against myeloma cancer cell-associated antigens." ;
  rdfs:subClassOf obo:VO_0005492 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0000381 a rdfs:Class ;
  rdfs:label "sublingual vaccination" ;
  rdfs:subClassOf obo:VO_0003021 .

obo:VO_0002152 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1761.15)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0016697 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0003237 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML [Recombivax]" ;
  rdfs:subClassOf obo:VO_0010737 .

obo:VO_0018472 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 10 by Abacus Medicine" ;
  rdfs:subClassOf obo:VO_0018455 .

obo:VO_0019925 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Prefilled Syringe [Agriflu 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019923 , obo:VO_0020308 .

obo:VO_0016102 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0015993 .

obo:VO_0010730 a rdfs:Class ;
  rdfs:label "Pediacel vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000744 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0015248 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015245 .

obo:VO_0005190 a rdfs:Class ;
  rdfs:label "IMP CoVac-1 vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine developed by University Hospital Tuebingen" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0020246 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0003335 .

obo:VO_0019740 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0007672 a rdfs:Class ;
  rdfs:label "HLA-A1, HLA-A2, and CD40-ligand pulsed dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine made from a person's white blood cells mixed with tumor proteins (HLA-A1- and HLA-A2.1-restricted peptides derived from melanoma-associated tumor antigens) and CD40-ligand, and may make the body build an immune response to kill tumor cells. This is combined with denileukin diftitox, which " ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0016124 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015878 .

obo:VO_0003824 a rdfs:Class ;
  rdfs:label "FluMist Quadrivalent, 2018-2019 Formula Nasal Spray" ;
  rdfs:subClassOf obo:VO_0003820 .

obo:VO_0019649 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020489 .

obo:VO_0020881 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Viroflu] Box of 10" ;
  rdfs:subClassOf obo:VO_0020880 , obo:VO_0020884 .

obo:VO_0003966 a rdfs:Class ;
  rdfs:label "HEPLISAV-B Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003965 .

obo:VO_0000679 a rdfs:Class ;
  rdfs:label "Shigella sonnei vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000769 .

obo:VO_0016702 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 5 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0001420 a rdfs:Class ;
  rdfs:label "Salmonella Gallinarum gene" ;
  rdfs:comment "A bacterial gene that is from Salmonella Gallinarum." ;
  rdfs:subClassOf obo:VO_0000168 .

obo:VO_0004618 a rdfs:Class ;
  rdfs:label "BCG-DHTM vaccine" ;
  rdfs:subClassOf obo:VO_0003130 .

obo:VO_0000530 a rdf:Property ;
  rdfs:label "has vaccine vector" ;
  rdfs:comment "A type of 'has vaccine component' relation that is specifically for vaccine vector component" ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range obo:VO_0000599 ;
  rdfs:subPropertyOf obo:VO_0000520 .

obo:VO_0002528 a rdfs:Class ;
  rdfs:label "plcB from Listeria monocytogenes" ;
  rdfs:comment "A plcB mutant, in combination with an actA mutant, is attenuated in mice and induces significant protection from challenge with wild type L. monocytogenes" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001403 .

obo:VO_0015817 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015597 .

obo:VO_0007512 a rdfs:Class ;
  rdfs:label "CLL idiotypic DNA vaccine" ;
  rdfs:comment "A cancer vaccine that treats patients with Binet Stage A Chronic Lymphocytic Leukemia (CLL) by using a fragment of Deoxyribonucleic acid (DNA) containing the sequence of their own immunoglobulin gene. The vaccine is designed to generate an immune response and shrink or slow the CLL." ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0019276 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010423 .

obo:VO_0018371 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0003345 .

obo:VO_0000798 a rdfs:Class ;
  rdfs:label "Ifng from cattle" ;
  rdfs:subClassOf obo:VO_0000797 .

obo:VO_0002809 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi fla mutant vaccine" ;
  rdfs:comment "A flagella-less mutant of Borrelia burgdorferi (HB19Fla-) was attenuated in immunodeficient SCID mice. Mice were challenged 28 days later with virulent strain Sh. 2 and were protected from challenge" ;
  rdfs:subClassOf obo:VO_0000764 .

obo:VO_0000140 a rdfs:Class ;
  rdfs:label "agglutinating antibody role" ;
  rdfs:subClassOf obo:VO_0000148 .

obo:VO_0020643 a rdfs:Class ;
  rdfs:label "1 ML BCG, live, Connaught strain 20000 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0020642 , obo:VO_0020716 .

obo:VO_0020840 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Fluarix]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0002952 a rdfs:Class ;
  rdfs:label "Classical swine fever virus E(rns) mutant vaccine" ;
  rdfs:comment "An N269A/Q mutation in the E(rns) protein created an attenuated mutant in swine. This mutant was able to induce effective protection in swine against challenge with wild type CSFV" ;
  rdfs:subClassOf obo:VO_0001012 .

obo:VO_0017863 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 2.5 MG" ;
  rdfs:subClassOf obo:VO_0004860 .

obo:VO_0002734 a rdfs:Class ;
  rdfs:label "glycoprotein G from Pseudorabies virus" ;
  rdfs:comment "A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001442 .

obo:VO_0015016 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injection" ;
  rdfs:subClassOf obo:VO_0015017 , obo:VO_0020832 .

obo:VO_0020268 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 UNT/ML [TE Anatoxal Berna]" ;
  rdfs:subClassOf obo:VO_0003401 .

obo:NCBITaxon_813 a rdfs:Class ;
  rdfs:label "Chlamydia trachomatis" ;
  rdfs:subClassOf obo:NCBITaxon_810 .

obo:VO_0010744 a rdfs:Class ;
  rdfs:label "Typherix vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000671 , obo:VO_0000714 , obo:VO_0010451 .

obo:VO_0004269 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum MSA-2 subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000534 .

obo:VO_0018432 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23]" ;
  rdfs:subClassOf obo:VO_0018422 .

obo:VO_0017083 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017074 .

obo:VO_0005473 a rdfs:Class ;
  rdfs:label "CAF09b vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is a lipid-based vaccine adjuvent based on cationic surfactant dimethyl-dioctadecyl ammonium (DDA) combined with C-type lectin agonist monomycoloyl glycerol (MMG) and TLR3 agonist poly I:C. CAF09b is able to induce CD8+ T-cell response." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0003550 a rdfs:Class ;
  rdfs:label "Alphaproteobacteria vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003531 .

obo:VO_0005341 a rdfs:Class ;
  rdfs:label "VB10.2210 vaccine" ;
  rdfs:comment "A SARS-CoV-2 T-Cell-based DNA vaccine developed by Vaccibody AS" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0016645 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by A+S Unicare" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0000605 a rdfs:Class ;
  rdfs:label "obsolete Canada licensed human vaccine role" ;
  rdfs:comment "A Canada licensed vaccine role that indicates the vaccine is used for human" .

obo:VO_0019936 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Flulaval Quad 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020341 .

obo:VO_0000136 a rdfs:Class ;
  rdfs:label "adenovirus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses an adenovirus as the vector." ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0011365 a rdfs:Class ;
  rdfs:label "cancer DNA vaccine pSURV encoding Survivin" ;
  rdfs:comment "Gene name: Survivin" ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0010860 a rdfs:Class ;
  rdfs:label "VP24 from Reston ebolavirus" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0000280 a rdfs:Class ;
  rdfs:label "pMV60 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002343 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Vaccine" ;
  rdfs:subClassOf obo:VO_0001507 , obo:VO_0002338 .

obo:VO_0017339 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000742 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0010415 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0002099 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine (USDA: 13A1.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002394 , obo:VO_0007748 .

obo:VO_0016194 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Mtk" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:VO_0017287 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML / Bordetella pertussis 0.1 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0018777 .

obo:VO_0015954 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat] Box of 3" ;
  rdfs:subClassOf obo:VO_0015641 , obo:VO_0015728 , obo:VO_0016044 .

obo:VO_0016248 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015916 .

obo:VO_0017747 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax]" ;
  rdfs:subClassOf obo:VO_0017740 , obo:VO_0017741 , obo:VO_0017774 .

obo:OBI_0001933 a rdfs:Class ;
  rdfs:label "value specification" ;
  rdfs:comment "An information content entity that specifies a value within a classification scheme or on a quantitative scale."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0000017 a rdfs:Class ;
  rdfs:label "killed vaccine" ;
  rdfs:comment "whole organism vaccine that uses killed pathogen organism as its component." ;
  rdfs:subClassOf obo:VO_0000315 .

obo:VO_0006068 a rdfs:Class ;
  rdfs:label "SARS-COV-2 COVID-19 mRNA bivalent original/Omicron BA.1 Non-US Vaccine (Spikevax Bivalent) Moderna" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000455 , obo:VO_0005264 .

obo:VO_0007593 a rdfs:Class ;
  rdfs:label "class I HLA-A0201-restricted gp100209-2M peptide vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0003383 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 5 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:OPL_0000272 a rdfs:Class ;
  rdfs:label "Plasmodium hepatic merozoite" ;
  rdfs:comment "A Plasmodium merozoite that is produced in a hepatic schizont and released into the bloodstream of a vertebrate host. These forms invade erythrocytes." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000270 .

obo:OGG_3000885459 a rdfs:Class ;
  rdfs:label "panC" ;
  rdfs:comment "Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme)" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0004483 a rdfs:Class ;
  rdfs:label "Vaccinia virus DNA vaccine B5R" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000651 .

obo:VO_0000505 a rdfs:Class ;
  rdfs:label "EHEC O157 subunit vaccine using his-tagged N-terminal intimin" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:OPL_0000304 a rdfs:Class ;
  rdfs:label "Plasmodium erythrocytic trophozoite stage" ;
  rdfs:comment "An erythrocytic trophozoite stage in the Plasmodium life cycle that occurs in erythrocytes of a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000243 , obo:OPL_0000303 .

obo:VO_0020841 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Grippe-Impfstoff Csl]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0001246 a rdfs:Class ;
  rdfs:label "Menveo vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0003441 , obo:VO_0010444 .

obo:VO_0011337 a rdfs:Class ;
  rdfs:label "NAP" ;
  rdfs:comment "A study shows that vaccination of mice with HP-NAP (H. pylori NAP) induces protection against H. pylori challenge, and that the majority of infected patients produce antibodies specific for HP-NAP, suggesting an important role of this factor in immunity [PubMed: 10790422]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010855 .

obo:VO_0016618 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Paediatric] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016598 .

obo:VO_0020925 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.009 MG/ML" ;
  rdfs:subClassOf obo:VO_0003502 , obo:VO_0004914 .

obo:NCBITaxon_13489 a rdfs:Class ;
  rdfs:label "Dicentrarchus labrax" ;
  rdfs:subClassOf obo:NCBITaxon_13488 .

obo:VO_0016526 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0005389 a rdfs:Class ;
  rdfs:label "SQ vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0001550 a rdfs:Class ;
  rdfs:label "Feline Panleukopenia Killed Virus Vaccine (USDA: 1565.20)" ;
  rdfs:subClassOf obo:VO_0000389 , obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0007748 .

obo:VO_0020280 a rdfs:Class ;
  rdfs:label "typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003849 .

obo:VO_0000751 a rdfs:Class ;
  rdfs:label "Simian immunodeficiency virus vaccine" ;
  rdfs:comment "A viral vaccine that prevents against infection with Simian immunodeficiency virus." ;
  rdfs:subClassOf obo:VO_0000609 .

obo:VO_0002856 a rdfs:Class ;
  rdfs:label "Mannheimia haemolytica aroA mutant vaccine" ;
  rdfs:comment "An aroA mutant is highly attenuated in mice and induced significant protection after two doses from challenge with wild type M. haemolytica" ;
  rdfs:subClassOf obo:VO_0001523 .

obo:VO_0003287 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003340 .

obo:VO_0003958 a rdfs:Class ;
  rdfs:label "Infanrix Injectable Product" ;
  rdfs:subClassOf obo:VO_0000064 .

obo:VO_0005445 a rdfs:Class ;
  rdfs:label "licensed human immune globulin passive vaccine, intravenous" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0000624 a rdfs:Class ;
  rdfs:label "subunit vaccine role" ;
  rdfs:comment "A vaccine role that indicates the vaccine being a subunit vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0005326 a rdfs:Class ;
  rdfs:label "VSA-1 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is prepared by derivatizing a natural Momordica saponin in one chemical step. VSA-1 is chemically more stable than QS-21. VSA-1 is much less toxic than QS-21. The Momordica saponins are from sustainable sources and widely available." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0001916 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4359.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002350 .

obo:VO_0003364 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0018707 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 UNT" ;
  rdfs:subClassOf obo:VO_0015054 .

obo:VO_0003530 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Massachusetts-2-2012-like virus 50000000 MG/ML" ;
  rdfs:subClassOf obo:VO_0003526 .

obo:VO_0016053 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 100" ;
  rdfs:subClassOf obo:VO_0003259 .

obo:VO_0011482 a rdfs:Class ;
  rdfs:label "Td Polio Adsorbed vaccine" ;
  rdfs:comment "A multivalent vaccine against tetanus, diphtheria, and poliomyelitis." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000586 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0017758 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension [Infanrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0017757 , obo:VO_0017759 .

obo:VO_0010781 a rdfs:Class ;
  rdfs:label "Hepatitis B virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0003636 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016-2017 vaccine 0.25 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003634 .

obo:VO_0015990 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe Box of 25" ;
  rdfs:subClassOf obo:VO_0015485 , obo:VO_0015774 .

obo:VO_0010091 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA1" ;
  rdfs:comment "A GRA1 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0017458 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution [T Polio Adsorbed]" ;
  rdfs:subClassOf obo:VO_0017457 , obo:VO_0017459 .

obo:VO_0004204 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum pfCelTos protein vaccine" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0011159 a rdfs:Class ;
  rdfs:label "ORFF" ;
  rdfs:comment "An expression plasmid encoding both p35 and p40 subunits of IL-12 when co-administered with a recombinant open-reading frame (rORFF) gene from the LD1 locus of Leishmania donovani induces significant protection with around 82% protection in both liver and spleen of BALB/c mice when challenged with L. donovani [PubMed: 16413950]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0011309 a rdfs:Class ;
  rdfs:label "CP15/60" ;
  rdfs:comment "Preparturient cows were immunized three times over a six-week period with recombinant plasmid DNA encoding the Cryptosporidium parvum CP15/60 antigen by injecting the DNA in the mammary gland.  Colostrum from these cows contained Ab specific for C. parvum sporozoites and oocysts as indicated by immunofluorescence Ab (IFA) staining.  Mice receiving immune colostrum showed partial protection (about 50% reduction) against intestinal C. parvum development compared to mice receiving control colostrum. This protection was evident at a challenge dose of 10^3 C. parvum oocysts per mouse [PubMed: 10392628]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010842 .

obo:VO_0020455 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020440 .

obo:VO_0001419 a rdfs:Class ;
  rdfs:label "Salmonella Typhi gene" ;
  rdfs:comment "A bacterial gene that is from Salmonella Typhi." ;
  rdfs:subClassOf obo:VO_0000168 .

obo:VO_0018899 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0004164 a rdfs:Class ;
  rdfs:label "Neospora caninum MIC10 and p24 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001065 .

obo:VO_0001300 a rdfs:Class ;
  rdfs:label "Loxoribine vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that includes loxoribine which is a guanosine analog derivatized at position N7 and C8, and activates TLR-7." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0018419 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML Injectable Solution [Pneumovax 23]" ;
  rdfs:subClassOf obo:VO_0018380 , obo:VO_0018386 .

obo:VO_0019813 a rdfs:Class ;
  rdfs:label "influenza A virus A/Kansas/14/2017 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Switzerland/3330/2017 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray [FluMist Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020351 .

obo:VO_0020368 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Intramuscular Solution [Typhim V]" ;
  rdfs:subClassOf obo:VO_0020375 .

obo:VO_0016919 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 LFU/ML / Pertussis Vaccine 0.0468 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017306 .

obo:VO_0004890 a rdfs:Class ;
  rdfs:label "gH1-Qbeta vaccine" ;
  rdfs:comment "The gH1-Qbeta vaccine is a novel pandemic-influenza vaccine produced by covalently linking the globular head domain of haemagglutinin (gH1) from A/California/07/09 produced in E. coli to VLPs from the bacteriophage Qbeta" ;
  rdfs:subClassOf obo:VO_0000578 .

obo:VO_0002968 a rdfs:Class ;
  rdfs:label "Gallid herpesvirus 1 UL47 mutant vaccine" ;
  rdfs:comment "A UL47 mutant in avian infectious laryngotracheitis virus is attenuated and provides protection in chicken against subsequent challenge infection with virulent ILTV" ;
  rdfs:subClassOf obo:VO_0001488 .

obo:VO_0000580 a rdfs:Class ;
  rdfs:label "vaccine adjuvant" ;
  rdfs:comment "A vaccine component is a chemical substance added to a vaccine to enhance and direct the immune response to a protective antigen. Vaccine adjuvants may cause a range of serious side-effects." ;
  rdfs:subClassOf obo:VO_0000179 , obo:VO_0000850 .

obo:VO_0002441 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis-Mareks Disease vaccine" ;
  rdfs:subClassOf obo:VO_0001468 , obo:VO_0001488 , obo:VO_0012162 .

obo:VO_0002399 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0002392 , obo:VO_0002400 .

obo:VO_0005175 a rdfs:Class ;
  rdfs:label "ChulaCov19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine manufactured by Chulalongkorn University" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:NCBITaxon_9913 a rdfs:Class ;
  rdfs:label "Bos taurus" ;
  rdfs:subClassOf obo:NCBITaxon_27592 .

obo:VO_0015897 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 1" ;
  rdfs:subClassOf obo:VO_0003266 .

obo:VO_0016445 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:OGG_3000887603 a rdfs:Class ;
  rdfs:label "fadD26" ;
  rdfs:comment "Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0015915 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015629 , obo:VO_0015676 , obo:VO_0016023 .

obo:VO_0017823 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.03 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML [Meningitec]" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0010724 , obo:VO_0018789 .

obo:VO_0005453 a rdfs:Class ;
  rdfs:label "licensed human vaccinia immune globulin passive vaccine" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0016078 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015868 .

obo:VO_0019691 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0018009 a rdfs:Class ;
  rdfs:label "Poliomyelitis Virus Type 1 (Sabin Strain (Ls-C, 2ab)) Live Attenuated Oral Vaccine" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0003167 .

obo:VO_0011132 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Hawaii/01/1991(H3N2))" ;
  rdfs:comment "A DNA vaccine encoding HA (from Influenza A virus (A/Hawaii/01/1991(H3N2))), NP and M1 (from a 1989 strain) protected ferrets better against challenge with the antigenic drift variant A/Georgia/03/93 than did the inactivated vaccine from the 1992-93 influenza season. Researchers report that the same DNA vaccine protected ferrets against a second, further divergent, drift variant (A/Johannesburg/33/94) [PubMed: 9234535]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0004632 a rdfs:Class ;
  rdfs:label "HVT-ND vaccine" ;
  rdfs:subClassOf obo:VO_0001222 .

obo:VO_0020230 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain 100000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0020229 .

obo:VO_0015539 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Suspension [Engerix B]" ;
  rdfs:subClassOf obo:VO_0003416 , obo:VO_0010711 .

obo:VO_0017674 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) and tetanus toxoid conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000563 , obo:VO_0000664 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003396 .

obo:VO_0005135 a rdfs:Class ;
  rdfs:label "ChAdOx1-MERS-S vaccine" ;
  rdfs:comment "A MERS recombinant vector made of  Chimpanzee adenovirus Oxford 1 vector expressing S protein from MERS-CoV." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0004900 .

obo:VO_0017429 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / meningococcal group C polysaccharide Injectable Solution [Menitorix]" ;
  rdfs:subClassOf obo:VO_0017428 .

obo:VO_0020015 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 50000000 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 50000000 MG/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010417 .

obo:VO_0002567 a rdfs:Class ;
  rdfs:label "omp31 from B. melitensis" ;
  rdfs:comment "A omp31 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001400 .

obo:VO_0003800 a rdfs:Class ;
  rdfs:label "0.5 ML Shingrix 0.1 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003799 .

obo:VO_0007069 a rdfs:Class ;
  rdfs:label "Recombinant Adenovirus-p53 SCH-58500 Vaccine" ;
  rdfs:comment "A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity. Recombinant adenovirus-p53 SCH-58500 delivers p53 into tumor cells, which may result in p53-mediated cell cycle arrest and apoptosis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0005462 a rdfs:Class ;
  rdfs:label "influenza, injectable, quadrivalent, preservative free, pediatric" ;
  rdfs:subClassOf obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0016590 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016585 .

obo:VO_0018382 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML [Pneumopur]" ;
  rdfs:subClassOf obo:VO_0018400 .

obo:VO_0016970 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 50 LFU/ML / Pertussis Vaccine 24 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017426 .

obo:VO_0015005 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Injection [Twinrix]" ;
  rdfs:subClassOf obo:VO_0003451 .

obo:VO_0001670 a rdfs:Class ;
  rdfs:label "Coccidiosis Live Oocysts, Chicken Isolates Vaccine (USDA: 1431.55)" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:VO_0001365 a rdfs:Class ;
  rdfs:label "Crimean-Congo Haemorrhagic Fever vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with CCHF virus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0019960 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:OPL_0000261 a rdfs:Class ;
  rdfs:label "hepatic trophozoite stage" ;
  rdfs:comment "A trophozoite stage in some protozoan parasite life cycle that occurs in hepatocytes." ;
  rdfs:subClassOf obo:OPL_0000057 .

obo:VO_0006057 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent booster preservative free 50 mcg/0.5 mL or 25 mcg/0.25 mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0007487 a rdfs:Class ;
  rdfs:label "gp100-Pulsed Peripheral Blood Mononuclear Cell vaccine" ;
  rdfs:comment "Peripheral blood lymphocytes (PBL) harvested from host blood and stimulated in vitro with tumor-specific gp 100 antigen. 'Pulsing' PBL with gp100, a tumor associated antigen (TAA) commonly expressed by melanoma cells, may increase melanoma-reactive cytotoxic lymphocytes (CTL) in the PBL cell population. Autologous gp100-pulsed PBL have been administered to melanoma patients in order to augment cytotoxic immune responses to melanoma." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0011461 a rdfs:Class ;
  rdfs:label "Coccidioides posadasii DNA vaccine encoding PRA protein" ;
  rdfs:comment "a Coccidioides vaccine that contains C. posadasii DNA vaccine encoding PRA protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012179 .

obo:VO_0020636 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0021028 .

obo:VO_0018538 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 12 BAU/ML Injectable Suspension [Ixiaro] by Eco.Pharma.Supply" ;
  rdfs:subClassOf obo:VO_0018537 .

obo:VO_0001878 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45H5.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002331 .

obo:VO_0003799 a rdfs:Class ;
  rdfs:label "Shingrix vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003797 , obo:VO_0020282 .

obo:VO_0003241 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [Recombivax]" ;
  rdfs:subClassOf obo:VO_0003237 .

obo:VO_0004086 a rdfs:Class ;
  rdfs:label "V-LSGPC vaccine" ;
  rdfs:subClassOf obo:VO_0012177 .

obo:VO_0015926 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015633 , obo:VO_0015694 , obo:VO_0016031 .

obo:VO_0007460 a rdfs:Class ;
  rdfs:label "multi-peptide CMV-modified vaccinia ankara vaccine" ;
  rdfs:comment "Gene name: UL83" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005427 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0020970 a rdfs:Class ;
  rdfs:label "Influenza Virus Fragmented, Inactivated, Strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain A / South Australia / 55/2014 Ivr-175 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0020969 .

obo:VO_0010128 a rdfs:Class ;
  rdfs:label "influenza, live, intranasal, quadrivalent vaccine" ;
  rdfs:subClassOf obo:VO_0001178 , obo:VO_0003495 .

obo:VO_0010079 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi TcTASV-C" ;
  rdfs:comment "A TcTASV-C protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0018905 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0006087 a rdfs:Class ;
  rdfs:label "Vaccinia smallpox monkeypox vaccine live attenuated preservative free subcutaneous or intradermal injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010452 .

obo:VO_0017717 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0017714 , obo:VO_0017725 , obo:VO_0017782 .

obo:VO_0019314 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluarix 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020314 .

obo:VO_0016434 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0016608 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Twinrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0016591 , obo:VO_0016613 .

obo:VO_0020084 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain 158000000 UNT/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001178 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0019261 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Idaho/07/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Indiana/08/2018 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020332 .

obo:VO_0015697 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 50" ;
  rdfs:subClassOf obo:VO_0015567 , obo:VO_0015786 .

obo:VO_0020818 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0001176 , obo:VO_0003455 , obo:VO_0010415 .

obo:VO_0010043 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum MSP1" ;
  rdfs:comment "A MSP1 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0004176 a rdfs:Class ;
  rdfs:label "Leishmania major H1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001231 .

obo:VO_0002808 a rdfs:Class ;
  rdfs:label "Bordetella pertussis dnt mutant vaccine" ;
  rdfs:comment "A live attenuated B. pertussis vaccine strain BPZE1, developed by deleting dnt gene, protects mice upon a single intranasal administration" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0018904 a rdfs:Class ;
  rdfs:label "influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0003236 a rdfs:Class ;
  rdfs:label "Hepatyrix vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000950 , obo:VO_0010438 , obo:VO_0010451 .

obo:VO_0001116 a rdfs:Class ;
  rdfs:label "survival of live vaccine inside host" ;
  rdfs:comment "Survival of live vaccine inside host is a process that represents the survival of a live vaccine inside its host. The time of the survival is often important for the success of the live vaccine." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0016634 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0016620 .

obo:VO_0020227 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, vector non-replicating" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0020606 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020885 .

obo:VO_0011541 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding NA from influenza A virus (A/chicken/Henan/12/2004(H5N1))" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0002883 a rdfs:Class ;
  rdfs:label "Salmonella Typhi galE mutant vaccine" ;
  rdfs:comment "A gal E mutant in strain Ty2 was isolated, attenuated, and protected mice against lethal challenge" ;
  rdfs:subClassOf obo:VO_0000671 .

obo:VO_0017206 a rdfs:Class ;
  rdfs:label "1 ML tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution [Tetabulin]" ;
  rdfs:subClassOf obo:VO_0017205 , obo:VO_0017534 .

obo:VO_0018459 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 20" ;
  rdfs:subClassOf obo:VO_0018433 , obo:VO_0018443 .

obo:VO_0019317 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Agriflu 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0001176 , obo:VO_0004914 , obo:VO_0020307 .

obo:VO_0019444 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 18 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0000788 a rdfs:Class ;
  rdfs:label "adenoviral vector Ad5 expressing SIV gag protein vaccine" ;
  rdfs:comment "A recombinant adenovirus (Ad5) expressing the codon-optimized SIV gag gene. PMID:11797011." ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0000358 a rdfs:Class ;
  rdfs:label "Brucella recombinant SurA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0001221 .

obo:VO_0003583 a rdfs:Class ;
  rdfs:label "Fluzone 2015-2016 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015081 .

obo:VO_0004824 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G3 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010449 .

obo:VO_0004852 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 0.05 MG/ML [Bexsero]" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0003066 .

obo:VO_0017930 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.01 MG Injection" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0003380 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003381 .

obo:VO_0017978 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.1 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.1 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020125 .

obo:VO_0010902 a rdfs:Class ;
  rdfs:label "BotA" ;
  rdfs:comment "A completely synthetic gene encoding fragment C, a approximately 50-kDa fragment, of botulinum neurotoxin serotype A was constructed from oligonucleotides.  Mice given three subcutaneous vaccinations were protected against an intraperitoneal administration of 10^6 50% lethal doses (ID50) of serotype A toxin [PubMed: 7790092]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010762 .

obo:VO_0016028 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 2" ;
  rdfs:subClassOf obo:VO_0015667 , obo:VO_0015778 .

obo:NCBITaxon_2096 a rdfs:Class ;
  rdfs:label "Mycoplasmoides gallisepticum" ;
  rdfs:subClassOf obo:NCBITaxon_2790996 .

obo:VO_0001127 a rdfs:Class ;
  rdfs:label "live attenuated Brucella vaccine" ;
  rdfs:comment "live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella infection." ;
  rdfs:subClassOf obo:VO_0000025 , obo:VO_0001217 .

obo:VO_0004310 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine NA-DNA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0010737 a rdfs:Class ;
  rdfs:label "Recombivax HB vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000714 , obo:VO_0010439 .

obo:VO_0016799 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Diphtherie-Adsorbat-Impfstoff Behring] Box of 10" ;
  rdfs:subClassOf obo:VO_0016724 , obo:VO_0016741 , obo:VO_0016819 .

obo:VO_0007129 a rdfs:Class ;
  rdfs:label "XBP1-US/XBP1-SP/CD138/CS1 Multipeptide Vaccine PVX-410" ;
  rdfs:comment "A cancer vaccine containing immunogenic, HLA-A2-specific epitopes derived from X-box-binding protein 1-unspliced (XBP1-US), XBP1-spliced (SP), syndecan-1 (CD138), and CS1 (CD2 subset 1, CRACC, SLAMF7, CD319) with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration, XBP1-US/XBP1-SP/CD138/CS1 multipeptide vaccine PVX-410 may stimulate the immune system to induce a cytotoxic T-lymphocyte response against the four myeloma-specific antigens. The tumor associated antigens (TAAs) XBP1-US, XBP1-SP, CD138 and CS1, are overexpressed on the surface of multiple myeloma (MM) cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0002359 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Campylobacter Fetus-Haemophilus Somnus-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002360 , obo:VO_0003535 .

obo:VO_0006076 a rdfs:Class ;
  rdfs:label "tetanus toxoid not adsorbed" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010436 .

obo:VO_0016967 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection Box of 5" ;
  rdfs:subClassOf obo:VO_0016963 , obo:VO_0017424 .

obo:VO_0003217 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 11A vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0016033 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0015668 , obo:VO_0015785 .

obo:VO_0016440 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0019705 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003627 .

obo:VO_0018421 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumopur]" ;
  rdfs:subClassOf obo:VO_0018382 , obo:VO_0018385 .

obo:VO_0003676 a rdfs:Class ;
  rdfs:label "Fluvirin 2015-2016 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003675 .

obo:VO_0017623 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] Box of 50" ;
  rdfs:subClassOf obo:VO_0017620 , obo:VO_0017630 .

obo:VO_0000600 a rdfs:Class ;
  rdfs:label "vaccinia virus vector" ;
  rdfs:comment "an orthopoxvirus vaccine vector that uses vaccinia virus as the vector" ;
  rdfs:subClassOf obo:VO_0001146 .

obo:VO_0010123 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii TgNTPase-II" ;
  rdfs:comment "A TgNTPase-II protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0001347 a rdfs:Class ;
  rdfs:label "non-toxic mutant E112K of Cholera Toxin mCT-E112K vaccine adjuvant" ;
  rdfs:comment "A microbial derived vaccine adjuvant made of E112K mC,  a mutated CT created by substituting a single amino acid in the ADP-ribosyltransferase active centre, glutamate to lysine at position 112." ;
  rdfs:subClassOf obo:VO_0001348 .

obo:VO_0019303 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Agriflu 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019301 , obo:VO_0020308 .

obo:VO_0019105 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010433 .

obo:VO_0017663 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Tetasorbat]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0016899 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017276 .

obo:VO_0015202 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015200 .

obo:VO_0017302 a rdfs:Class ;
  rdfs:label "Bordetella pertussis / diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017799 .

obo:VO_0010800 a rdfs:Class ;
  rdfs:label "Pseudorabies virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0018540 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection [Cervarix]" ;
  rdfs:subClassOf obo:VO_0018539 , obo:VO_0018652 .

obo:VO_0017056 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] Box of 50 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017055 .

obo:VO_0012409 a rdfs:Class ;
  rdfs:label "MPT83" ;
  rdfs:comment "A single DNA vaccine encoding the MPT-83 tuberculosis antigens evoked partial protection against an aerogenic challenge with M. tuberculosis Erdman in the mouse model of pulmonary tuberculosis [PubMed: 10715531]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0017810 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / meningococcal group C polysaccharide" ;
  rdfs:subClassOf obo:VO_0015014 .

obo:VO_0018335 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabivac] Box of 5 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0018321 .

obo:VO_0016400 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 25 by Mtk" ;
  rdfs:subClassOf obo:VO_0015958 , obo:VO_0015964 .

obo:VO_0001018 a rdfs:Class ;
  rdfs:label "live attenuated Newcastle disease virus vaccine" ;
  rdfs:comment "A live attenuated viral vaccine that protects aganist Newcastle disease virus infection." ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0001222 .

obo:VO_0002854 a rdfs:Class ;
  rdfs:label "Francisella tularensis wbtA mutant vaccine" ;
  rdfs:comment "A wbtA mutant in Francisella tularensis was attenuated and provided protection in mice against challenge with an otherwise lethal dose of either F. tularensis LVS or a fully virulent clinical isolate of F. tularensis type B" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0004369 a rdfs:Class ;
  rdfs:label "Herpes simplex virus DNA vaccine gBDNA encoding gB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0004540 a rdfs:Class ;
  rdfs:label "Mycobacterium avium DNA vaccine DNA-Av35/p2AIL12" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002501 .

obo:VO_0004153 a rdfs:Class ;
  rdfs:label "Varicella subunit vaccine encoding gI and gE glycoproteins" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000669 .

obo:VO_0002539 a rdfs:Class ;
  rdfs:label "obsolete panD from Mycobacterium tuberculosis" ;
  rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" .

obo:NCBITaxon_1238 a rdfs:Class ;
  rdfs:label "Piscirickettsia salmonis" ;
  rdfs:subClassOf obo:NCBITaxon_72273 .

obo:VO_0020975 a rdfs:Class ;
  rdfs:label "Influenza Virus Fragmented, Inactivated, Strain B / Phuket / 3073/2013 0.00752 MG/ML" ;
  rdfs:subClassOf obo:VO_0020973 .

obo:VO_0019990 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0004516 a rdfs:Class ;
  rdfs:label "DNA vaccine expressing PspA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000675 .

obo:VO_0001762 a rdfs:Class ;
  rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0000712 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0004443 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine pUB-TRP-2 encoding a fusion protein linking murine ubiquitin (UB) to the N-terminus of the full-length mTRP-2" ;
  rdfs:comment "Gene name: Ubiquitin" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0002983 a rdfs:Class ;
  rdfs:label "Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine" ;
  rdfs:comment "A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ;
  rdfs:subClassOf obo:VO_0000750 .

obo:VO_0018866 a rdfs:Class ;
  rdfs:label "influenza A virus A/Kansas/14/2017 (H3N2) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0020165 a rdfs:Class ;
  rdfs:label "pertussis vaccine 600 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017808 .

obo:VO_0010452 a rdfs:Class ;
  rdfs:label "licensed human smallpox virus vaccine" ;
  rdfs:comment "Smallpox virus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000651 .

obo:VO_0002035 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.13)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002326 , obo:VO_0007748 .

obo:VO_0002089 a rdfs:Class ;
  rdfs:label "Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Modified Live Virus & Avirulent Live Culture Vaccine (USDA: 12X1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002386 , obo:VO_0007748 .

obo:VO_0017490 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017489 , obo:VO_0017496 .

obo:VO_0015779 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0015595 .

obo:IAO_8000003 a rdfs:Class ;
  rdfs:label "main release ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be the primary release product and the one consumed by the majority of tools."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:VO_0015497 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0015496 , obo:VO_0015545 .

obo:VO_0004308 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine NP DNA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0003852 a rdfs:Class ;
  rdfs:label "Typhim Vi Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003850 .

obo:VO_0000180 a rdfs:Class ;
  rdfs:label "vaccine-induced cell activation" ;
  rdfs:subClassOf obo:VO_0000287 .

obo:VO_0000888 a rdfs:Class ;
  rdfs:label "phenol vaccine preservative" ;
  rdfs:subClassOf obo:VO_0000851 .

obo:VO_0015746 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015495 , obo:VO_0015811 .

obo:VO_0004326 a rdfs:Class ;
  rdfs:label "Rabies virus DNA vaccine pSG5rab.gp" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000650 .

obo:VO_0005110 a rdfs:Class ;
  rdfs:label "SARS ADS-MVA vaccine" ;
  rdfs:comment "A SARS recombinant vector vaccine that is made from a recombinant live-attenuated modified vaccinia virus Ankara (MVA) that had a full-length SARS-CoV envelope Spike (S) glycoprotein gene introduced into the deletion III region of the MVA genome." ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0000825 a rdfs:Class ;
  rdfs:label "DNA and poxvirus priming-boosting SIV vaccine" ;
  rdfs:comment "A SIV vaccine that is composed of a DNA vaccine and a poxvirus vector expressing the same SIV antigens. PMID:15258286." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0021011 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0019884 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0011072 a rdfs:Class ;
  rdfs:label "IglC1" ;
  rdfs:comment "Mice immunized with rLm/iglC were protected against lethal challenge with F. tularensis LVS administered by the intranasal route, a route chosen to mimic airborne infection, and, most importantly, against aerosol challenge with the highly virulent Type A F. tularensis SchuS4 strain [PubMed: 19126421]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:VO_0000459 a rdfs:Class ;
  rdfs:label "E. coli O157:H7 subunit vaccine expressing Esps and Tir" ;
  rdfs:subClassOf obo:VO_0000628 , obo:VO_0001466 .

obo:VO_0019765 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hawaii/66/2019 (H1N1) antigen 158000000 UNT/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML / influenza B virus B/Washington/02/2019 antigen 158000000 UNT/ML Nasal Spray [Flumist Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020352 .

obo:VO_0018258 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT [Imovax]" ;
  rdfs:subClassOf obo:VO_0018269 .

obo:VO_0002054 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Standard & Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C8.44)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0019189 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019188 , obo:VO_0019660 .

obo:VO_0001747 a rdfs:Class ;
  rdfs:label "Canine Parainfluenza Modified Live Virus Vaccine (USDA: 1421.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0001526 , obo:VO_0007748 .

obo:VO_0010304 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/60/2008 antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003519 , obo:VO_0010301 .

obo:VO_0010951 a rdfs:Class ;
  rdfs:label "EsxB" ;
  rdfs:comment "The 10-kDa culture filtrate protein (CFP-10, esxB) and 6-kDa early secretory antigen of T cells (ESAT-6) are secreted in abundance by Mycobacterium tuberculosis.  Study demonstrated that protective immunity is induced by CFP-10 DNA vaccination in C3H mice as measured by a CFU reduction in the lung and spleen 4 and 8 weeks after challenge with M. tuberculosis [PubMed: 18332205]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0002676 a rdfs:Class ;
  rdfs:label "obsolete icsA/virG from Shigella" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" .

obo:VO_0010267 a rdfs:Class ;
  rdfs:label "host pregnancy datum" ;
  rdfs:comment "A measurement datum that records to involvement of the host of the pregnancy process." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0010360 a rdfs:Class ;
  rdfs:label "TDVAX (NDC 14362-0111) vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0000398 a rdfs:Class ;
  rdfs:label "microencapsulated Brucella melitensis mutant vaccine" ;
  rdfs:comment "A live attenuated Brucella melitensis vaccine that is composed of live Brucella melitensis attenuated mutant vjbR::Tn5 (BMEII1116) delivered using a microsphere delivery system." ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0015339 a rdfs:Class ;
  rdfs:label "Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 , obo:VO_0010451 , obo:VO_0015337 .

obo:VO_0011191 a rdfs:Class ;
  rdfs:label "NcPDI" ;
  rdfs:comment "A 90% protection rate was achieved following intra-nasal vaccination with recNcPDI emulsified in cholera toxin employing the C57Bl/6 mouse cerebral infection model when challenged with Neospora caninum tachyzoites [PubMed: 19835644]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0020699 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020698 , obo:VO_0020735 .

obo:VO_0018526 a rdfs:Class ;
  rdfs:label "0.5 ML Anthrax Vaccine Adsorbed 0.1 MG/ML Injectable Suspension [Biothrax]" ;
  rdfs:subClassOf obo:VO_0004215 , obo:VO_0018525 , obo:VO_0018596 .

obo:VO_0018118 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella virus vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0004730 a rdfs:Class ;
  rdfs:label "ALVAC-AI-H5(H5N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0003788 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2016-2017 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003787 .

obo:VO_0011112 a rdfs:Class ;
  rdfs:label "HA from Equine influenza virus H3N8" ;
  rdfs:comment "Skin and mucosal vaccination provided complete protection from clinical signs of infection with ponies subjected to a challenge infection of Equine influenza virus, while skin vaccination provided partial protection; DNA vaccination provided partial protection from viral shedding [PubMed: 10403592]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0010011 a rdfs:Class ;
  rdfs:label "Giardia  lamblia alpha-enolase" ;
  rdfs:comment "A alpha-enolase protein that is part of Giardia  lamblia" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015483 .

obo:VO_0020423 a rdfs:Class ;
  rdfs:label "typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10" ;
  rdfs:subClassOf obo:VO_0020392 , obo:VO_0020427 .

obo:VO_0019716 a rdfs:Class ;
  rdfs:label "influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML [Afluria Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0020305 .

obo:VO_0015898 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 10" ;
  rdfs:subClassOf obo:VO_0003266 .

obo:VO_0010032 a rdfs:Class ;
  rdfs:label "Neospora caninum GRA6" ;
  rdfs:comment "A GRA6 protein that is part of Neospora caninum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0020148 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine Injection [Menquadfi]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0003441 , obo:VO_0010436 , obo:VO_0010444 .

obo:VO_0000224 a rdfs:Class ;
  rdfs:label "hypersensitivity to antibiotic" ;
  rdfs:subClassOf obo:VO_0000207 .

obo:VO_0016981 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group C polysaccharide 0.02 MG/ML / tetanus toxoid vaccine, inactivated 0.04 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017453 .

obo:VO_0017023 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0016995 , obo:VO_0017500 .

obo:VO_0003412 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injection [PedvaxHIB]" ;
  rdfs:subClassOf obo:VO_0000083 , obo:VO_0003410 , obo:VO_0020832 .

obo:VO_0017774 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated Injectable Suspension [Repevax]" ;
  rdfs:subClassOf obo:VO_0017770 .

obo:VO_0020693 a rdfs:Class ;
  rdfs:label "Aconitum napellus extract / ferrous cation / Gelsemium Sempervirens Preparation / Gentiana lutea root extract / Influenza A virus / Lactate / Luffa operculata whole extract / VERATRUM ALBUM Preparation Oral Solution [Metavirulent]" ;
  rdfs:subClassOf obo:VO_0020692 .

obo:VO_0018126 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Vaccine / Rubella virus / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000737 .

obo:VO_0020990 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigens, strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain Nib-88 0.00752 MG/ML" ;
  rdfs:subClassOf obo:VO_0020988 .

obo:NCBITaxon_76803 a rdfs:Class ;
  rdfs:label "Arteriviridae" ;
  rdfs:subClassOf obo:NCBITaxon_76804 .

obo:VO_0005074 a rdfs:Class ;
  rdfs:label "pDNAVACC DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pDNAVACC." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000187 a rdfs:Class ;
  rdfs:label "muramyl dipeptide vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant formulated to correspond to a component found in a water-soluble extract of cell walls of mycobacteria used in complete Freund's adjuvant (CFA)." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0004813 a rdfs:Class ;
  rdfs:label "v2RVFH vaccine" ;
  rdfs:subClassOf obo:VO_0001455 .

obo:VO_0018787 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0005807 a rdfs:Class ;
  rdfs:label "Pb(PfCS@UIS4) vaccine" ;
  rdfs:comment "A Live attenuated vaccine Pb(PfCS@UIS4) that immunizes against Plasmodium falciparum sporozoite." ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000455 .

obo:VO_0017967 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injection [Meningitec] Box of 10" ;
  rdfs:subClassOf obo:VO_0017952 .

obo:VO_0001596 a rdfs:Class ;
  rdfs:label "avian influenza H7N2 Subtype, Killed Virus Vaccine (USDA: 10F5.12)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0015324 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Injectable Suspension [ViATIM]" ;
  rdfs:subClassOf obo:VO_0015323 , obo:VO_0015335 .

obo:VO_0011231 a rdfs:Class ;
  rdfs:label "Glycoprotein" ;
  rdfs:comment "A DNA vaccine based on lysosome-targeted glycoprotein of the rabies virus was evaluated in BALB/c mice. It imparted partial protection (60%) against challenge with 20 LD(50) of the challenge virus standard (CVS) strain of rabies virus [PubMed: 19741168]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010788 .

obo:VO_0011184 a rdfs:Class ;
  rdfs:label "NspA from N. meningitidis" ;
  rdfs:comment "NspA-containing outer membrane vesicles conferred protection against otherwise lethal intraperitoneal challenge of mice with N. meningitidis serogroup B, and sera raised against them mediated opsonophagocytosis of meningococcal strains expressing this antigen [PubMed: 15501782]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0017382 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0002303 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002480 .

obo:VO_0000669 a rdfs:Class ;
  rdfs:label "Varicella-zoster virus vaccine" ;
  rdfs:comment "a Herpesvirus vaccine that is used against Varicella-zoster virus infection." ;
  rdfs:subClassOf obo:VO_0003537 .

obo:VO_0005085 a rdfs:Class ;
  rdfs:label "VAT00002 vaccine" ;
  rdfs:comment "A stabilised pre-fusion SARS-CoV-2 spike protein vaccine produced in a baculovirus expression system and manufactured by Sanofi Pasteur and GlaxoSmithKline" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0019844 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0016840 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 LFU/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0016761 .

obo:VO_0019725 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0018164 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML" ;
  rdfs:subClassOf obo:VO_0015052 .

obo:VO_0007209 a rdfs:Class ;
  rdfs:label "Adenovirus-p53 transduced dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous dendritic cells (DCs) transduced with a recombinant adenovirus encoding p53 peptide, with potential immunomodulating activity. Intradermal vaccination with adenoviral-p53 transduced dendritic cell vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing mutant p53, resulting in tumor cell lysis. p53, a tumor suppressor gene, is mutated in many tumor cells, resulting in the loss of apoptosis regulation and abnormal cell proliferation." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0020910 a rdfs:Class ;
  rdfs:label "Influenza A virus Injectable Suspension [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0020907 .

obo:VO_0000616 a rdfs:Class ;
  rdfs:label "animal model of vaccine research" ;
  rdfs:comment "Animal model of vaccine research is a role played by some organism (e.g., mouse) that is used for vaccine research." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0005176 a rdfs:Class ;
  rdfs:label "obsolete COH04S1" .

obo:DOID_10652 a rdfs:Class ;
  rdfs:label "Alzheimer's disease"@en ;
  rdfs:comment "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid."@en ;
  rdfs:subClassOf obo:DOID_331 .

obo:VO_0018139 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 17500 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018243 .

obo:VO_0018668 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 1000 MG [Rotarix]" ;
  rdfs:subClassOf obo:VO_0010738 , obo:VO_0018667 .

obo:VO_0015818 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015597 .

obo:VO_0011546 a rdfs:Class ;
  rdfs:label "Streptococcus equi Subunit CNE protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000948 .

obo:VO_0020986 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, strain A / Victoria / 361/2011 H3N2 - Derived Strain Used Ivr-165 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0020982 .

obo:VO_0016750 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Pur] Box of 2" ;
  rdfs:subClassOf obo:VO_0016713 , obo:VO_0016769 .

obo:VO_0020219 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.1 MG/ML [Comirnaty]" ;
  rdfs:subClassOf obo:VO_0004987 , obo:VO_0020218 .

obo:VO_0020252 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0003337 .

obo:VO_0002119 a rdfs:Class ;
  rdfs:label "Canine Parainfluenza-Bordetella Bronchiseptica Modified Live Virus, Avirulent Live Culture Vaccine (USDA: 14M1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002418 , obo:VO_0007748 .

obo:VO_0005440 a rdfs:Class ;
  rdfs:label "licensed human anthrax immune globulin passive vaccine" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0019694 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0001516 a rdfs:Class ;
  rdfs:label "Turkey hemorrhagic enteritis virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Turkey hemorrhagic enteritis virus (Turkey adenoirus 3) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000037 .

obo:VO_0004905 a rdfs:Class ;
  rdfs:label "MERS-CoV S protein with alum and CpG adjuvant vaccine" ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0015233 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Injectable Suspension [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0003236 , obo:VO_0015232 .

obo:VO_0016129 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015881 .

obo:VO_0018461 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumopur] Box of 10" ;
  rdfs:subClassOf obo:VO_0018434 , obo:VO_0018445 .

obo:VO_0017982 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec] Box of 1 by Nuron Biotech" ;
  rdfs:subClassOf obo:VO_0017965 .

obo:VO_0000198 a rdfs:Class ;
  rdfs:label "chickenpox virus gene" ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0002748 a rdfs:Class ;
  rdfs:label "C protein from West Nile virus" ;
  rdfs:comment "A virus with a C protein mutation is attenuated in mice and induces significant protection from challenge with wild type West Nile virus" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001448 .

obo:VO_0010980 a rdfs:Class ;
  rdfs:label "NadA" ;
  rdfs:comment "Protective antigen [PubMed: 16825336][PubMed: 12045242] with GeneID: 902509. However, according to sequence analysis, this nadA is not the same NadA that was found to be protective antigen  [PubMed: 16825336][PubMed: 12045242]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0020820 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.02 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Daptacel]" ;
  rdfs:subClassOf obo:VO_0000029 .

obo:VO_0020744 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 120 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020742 , obo:VO_0020753 .

obo:NCBITaxon_5664 a rdfs:Class ;
  rdfs:label "Leishmania major" ;
  rdfs:subClassOf obo:NCBITaxon_38568 .

obo:VO_0003052 a rdfs:Class ;
  rdfs:label "percutaneous vaccination" ;
  rdfs:comment "Administration of a drug by the way of absorption through the skin, usually for systemic action. The route allows sustained therapeutic plasma drug levels and avoids first pass effect. Simplicity of administration tends to result in high patient compliance.|YL" ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0007643 a rdfs:Class ;
  rdfs:label "modified Vaccinia virus ankara vaccine expressing p53" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0019508 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018869 , obo:VO_0019512 .

obo:VO_0019852 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:VO_0000944 a rdfs:Class ;
  rdfs:label "Vibrio cholerae and E. coli vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000041 , obo:VO_0000763 .

obo:VO_0020849 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Viroflu]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0004842 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0004838 .

obo:OPL_0000286 a rdfs:Class ;
  rdfs:label "Plasmodium gamete stage" ;
  rdfs:comment "A gamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000181 , obo:OPL_0000260 .

obo:VO_0016735 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016721 .

obo:VO_0018226 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 5000 UNT / Rubella virus 1000 UNT Injection [Priorix]" ;
  rdfs:subClassOf obo:VO_0018224 , obo:VO_0018225 .

obo:VO_0000808 a rdfs:Class ;
  rdfs:label "rapid vaccination" ;
  rdfs:comment "A vaccination process that is implemented fast." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0020570 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Inflexal] Box of 10" ;
  rdfs:subClassOf obo:VO_0020569 , obo:VO_0020603 , obo:VO_0020868 .

obo:VO_0007011 a rdfs:Class ;
  rdfs:label "pNGVL3-hICD Vaccine" ;
  rdfs:comment "A plasmid DNA cancer vaccine encoding the intracellular domain (ICD) of the HER-2/neu proto-oncogene. Upon administration and after cellular uptake by skin or muscle cells, the pNGVL3-hICD vaccine plasmid expresses the HER-2/neu protein, which, after intracellular processing, may elicit both antigen-specific cytotoxic T-lymphocyte (CTL) and humoral immune responses against tumor cells expressing HER-2. The HER-2/neu ICD protein is highly immunogenic and, as a subdominant epitope, may be associated with decreased immune tolerance." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0004338 a rdfs:Class ;
  rdfs:label "VHSV DNA vaccine pCMV-vhsG encoding glycoprotein G" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001224 .

obo:VO_0005034 a rdfs:Class ;
  rdfs:label "VR1040 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label VR1040.  This plasmid contains four copies of the mouse immunostimulatory sequence and is similar to VR1012." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001635 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0015731 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 100" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015802 .

obo:OPL_0000380 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Toxoplasma gondii." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:NCBITaxon_727 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae" ;
  rdfs:subClassOf obo:NCBITaxon_724 .

obo:VO_0002326 a rdfs:Class ;
  rdfs:label "avian encephalomyelitis-fowl pox vaccine" ;
  rdfs:subClassOf obo:VO_0000985 , obo:VO_0001468 , obo:VO_0001522 .

obo:VO_0020993 a rdfs:Class ;
  rdfs:label "Influenza Virus Vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0003504 .

obo:VO_0015547 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0002169 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1776.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0019982 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Injectable Suspension [Fluzone 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019978 , obo:VO_0020480 .

obo:VO_0015507 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML [H B Vax]" ;
  rdfs:subClassOf obo:VO_0003423 .

obo:VO_0004171 a rdfs:Class ;
  rdfs:label "Leishmania major DNA vaccine encoding LACKp24, TSA, LmSTI1 and CPa" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001231 .

obo:VO_0004319 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 recombinant vector vaccine rLaSota/gDF encoding gD" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000987 .

obo:VO_0001149 a rdfs:Class ;
  rdfs:label "significant vaccine protection" ;
  rdfs:subClassOf obo:VO_0000247 .

obo:VO_0002622 a rdfs:Class ;
  rdfs:label "clpP from Salmonella Typhimurium" ;
  rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0006035 a rdfs:Class ;
  rdfs:label "meningococcal polysaccharide (groups A C Y W-135) tetanus toxoid conjugate vaccine 0.5mL dose preservative free" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0007055 a rdfs:Class ;
  rdfs:label "Vi capsular polysaccharide typhoid vaccine" ;
  rdfs:comment "A live attenuated bacteria injectable vaccine used to prevent typhoid, which is caused by Salmonella typhi." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000768 , obo:VO_0001217 .

obo:VO_0004401 a rdfs:Class ;
  rdfs:label "EAE DNA vaccine pZZ/MBP68-85 encoding MBP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002837 .

obo:VO_0007624 a rdfs:Class ;
  rdfs:label "intralesional bacile Calmette-Guerin (BCG) vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0004555 a rdfs:Class ;
  rdfs:label "Chlamydophila pneumoniae DNA vaccine pHSP-61" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012173 .

obo:VO_0010838 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0011471 a rdfs:Class ;
  rdfs:label "Eimeria tenella DNA vaccine EtMIC2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001137 .

obo:VO_0016211 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0006082 a rdfs:Class ;
  rdfs:label "Typhoid conjugate vaccine (non-US)" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010451 .

obo:IAO_0000013 a rdfs:Class ;
  rdfs:label "journal article"@en ;
  rdfs:comment "A report that is published in a journal."@en ;
  rdfs:subClassOf obo:IAO_0000088 , obo:IAO_0000311 .

obo:VO_0020671 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension [Bcg Medac] Box of 1 by Lamepro" ;
  rdfs:subClassOf obo:VO_0020670 .

obo:VO_0011109 a rdfs:Class ;
  rdfs:label "G glycoprotein from Infectious Hematopoietic Necrosis Virus" ;
  rdfs:comment "The DNA vaccine pIHNw-G encodes the glycoprotein of the fish rhabdovirus infectious hematopoietic necrosis virus (IHNV). Vaccine performance in rainbow trout was measured 3, 6, 13, 24, and 25 months after vaccination. At three months all fish vaccinated with 0.1 microg pIHNw-G had detectable neutralizing antibody (NAb) and they were completely protected from lethal IHNV challenge with a relative percent survival (RPS) of 100% compared to control fish [PubMed: 16154239]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010810 .

obo:VO_0018059 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018058 .

obo:VO_0005052 a rdfs:Class ;
  rdfs:label "APL023 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label APL023." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019593 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Nasal Spray [Flumist 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003806 , obo:VO_0010427 , obo:VO_0019592 .

obo:VO_0007282 a rdfs:Class ;
  rdfs:label "autologous dendritic cell vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0017845 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017895 .

obo:VO_0011310 a rdfs:Class ;
  rdfs:label "G glycoprotein from Hendra virus" ;
  rdfs:comment "A subunit vaccine formulation containing only recombinant, soluble, attachment glycoprotein G from HeV (sG(HeV)) and CpG adjuvant was evaluated as a potential NiV vaccine in the cat model.  Upon oronasal challenge with NiV (50,000TCID50), all vaccinated cats were protected from disease although virus was detected on day 21 post-challenge in one animal [PubMed: 18556094]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010843 .

obo:VO_0011379 a rdfs:Class ;
  rdfs:label "Bovine leukemia virus DNA vaccine encoding Tax" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012161 .

obo:VO_0020838 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Begripal]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0004294 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pIRES/HA encoding HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0015882 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015618 , obo:VO_0016003 .

obo:VO_0016455 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Veron" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0002991 a rdfs:Class ;
  rdfs:label "Rabies virus glycoprotein G mutant vaccine" ;
  rdfs:comment "A glycoprotein G mutant in rabies virus is attenuated. After a one-dose intramuscular vaccination, the ERAg3m virus protected 100% of mice and hamsters from lethal challenge. In co-infections, using a lethal dose of street rabies virus mixed with ERAg3m, 100% of hamsters and 90% of mice survived and were protected against subsequent infection" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0018170 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0018166 .

obo:VO_0017038 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0017036 .

obo:VO_0001268 a rdfs:Class ;
  rdfs:label "Montanide ISA 720 vaccine adjuvant" ;
  rdfs:comment "A Montanide vaccine adjuvant that is formulated as water-in-oil emulsions and induces high antibody titers in several animal species. It is a vaccine adjuvant composed of metabolizable oil and a surfactant system designed to make a water-in-oil emulsion. It has been used since 1992 in more than 50 clinical trials related to therapeutic vaccines against various diseases such as cancer and malaria." ;
  rdfs:subClassOf obo:VO_0001271 .

obo:VO_0019120 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0001431 a rdfs:Class ;
  rdfs:label "Equid herpesvirus gene" ;
  rdfs:comment "A viral gene that is from Equid herpesvirus 1." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0016328 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0016656 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Milinda Am" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0002329 a rdfs:Class ;
  rdfs:label "avian influenza-fowl pox vaccine" ;
  rdfs:subClassOf obo:VO_0000461 , obo:VO_0000985 .

obo:VO_0016287 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0016026 .

obo:VO_0007585 a rdfs:Class ;
  rdfs:label "Bacillus Calmette-Guerin (MER) vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0018157 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0018143 .

obo:VO_0016905 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Tripacel] Box of 5" ;
  rdfs:subClassOf obo:VO_0016904 , obo:VO_0016906 , obo:VO_0017285 .

obo:VO_0000343 a rdfs:Class ;
  rdfs:label "intranasal route by spray" ;
  rdfs:subClassOf obo:VO_0000341 .

obo:VO_0016476 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0003642 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003639 .

obo:VO_0003502 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003500 , obo:VO_0010415 .

obo:VO_0004562 a rdfs:Class ;
  rdfs:label "Leptospira interrogans DNA vaccine ompL1-pcDNA3.1(+)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000391 .

obo:VO_0011315 a rdfs:Class ;
  rdfs:label "PrM from Dengue Virus" ;
  rdfs:comment "A recombinant vaccinia virus that expressed the pre-M protein of Dengue 4 virus was constructed. Mice immunized with the recombinant virus were protected against subsequent dengue 4 encephalitis challenge [PubMed: 1926792]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010844 .

obo:VO_0018566 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0018561 .

obo:VO_0011101 a rdfs:Class ;
  rdfs:label "ICP27 from Herpes simplex virus type 1" ;
  rdfs:comment "Epitopes from the ICP27 (H1, H2), glycoprotein B (gB) and glycoprotein D (gD) proteins of HSV-1 were attached to either the J TCBL/ICBL or the G TCBL/ICBL. The JH1, JH2, JgB and JgD vaccines elicited DTH responses without antibody but conferred protection upon lethal challenge with HSV [PubMed: 15569635]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010834 .

obo:VO_0019560 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flucelvax Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020334 .

obo:VO_0016159 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0007465 a rdfs:Class ;
  rdfs:label "IL-2/Lptn gene-modified allogeneic neuroblastoma tumor cell vaccine" ;
  rdfs:comment "A cancer vaccine consisting of allogeneic neuroblastoma tumor cells have been genetically modified to secrete the human cytokine interleukin-2 (IL-2) and the human chemokine lymphotactin (Lptn) with potential immunostimulating and antineoplastic activities. Upon administration, IL-2 and Lptn are secreted by the IL-2/Lptn gene-modified allogeneic neuroblastoma tumor cell vaccine, potentially enhancing the cytotoxic T lymphocyte (CTL) response elicited by vaccine neuroblastoma tumor-associated antigens (TAAs) against host neuroblastoma tumor cells. Produced by activated progenitor T cells, Lptn belongs to the C chemokine subfamily and is a potent chemotactic factor for lymphocytes; IL-2 stimulates natural killer (NK) cells and may enhance a vaccine-elicited CTL immune response against tumor cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0020953 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML Nasal Spray Box of 5" ;
  rdfs:subClassOf obo:VO_0020950 .

obo:VO_0002834 a rdfs:Class ;
  rdfs:label "obsolete Edwardsiella tarda aroC/esrC mutant vaccine" ;
  rdfs:comment "An aroC and esrC mutant is attenuated in zebra fish. This mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 71.3%" .

obo:VO_0000039 a rdfs:Class ;
  rdfs:label "pBacPAK9 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015948 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites] Box of 10" ;
  rdfs:subClassOf obo:VO_0015639 , obo:VO_0015722 , obo:VO_0016040 .

obo:VO_0018276 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur]" ;
  rdfs:subClassOf obo:VO_0018256 , obo:VO_0018261 , obo:VO_0018284 .

obo:OPL_0000250 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum hepatic trophozoite stage" ;
  rdfs:comment "A hepatic trophozoite stage in the Plasmodium falciparum life cycle that occurs in hepatocytes of a human host." ;
  rdfs:subClassOf obo:OPL_0000251 , obo:OPL_0000261 , obo:OPL_0000306 .

obo:VO_0018882 a rdfs:Class ;
  rdfs:label "influenza A virus A/Minnesota/41/2019 (H3N2) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:VO_0019466 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0007482 a rdfs:Class ;
  rdfs:label "gp100 Adenovirus vaccine" ;
  rdfs:comment "A vaccine consisting of a replication-defective recombinant adenovirus that encodes the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. Vaccination with gp100 adenovirus vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0017157 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017613 .

obo:VO_0020654 a rdfs:Class ;
  rdfs:label "1 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0020646 , obo:VO_0021017 .

obo:OPL_0000206 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum macrogametocyte" ;
  rdfs:comment "A Plasmodium falciparum gametocyte that is a female gametocyte and found either in bloodstream of a human host or midgut of mosquito vector. The macrogametocyte is a precursor of the macrogamete." ;
  rdfs:subClassOf obo:OPL_0000249 , obo:OPL_0000268 .

obo:VO_0017324 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension [Act-HIB DTP]" ;
  rdfs:subClassOf obo:VO_0017323 .

obo:VO_0011220 a rdfs:Class ;
  rdfs:label "MSP3" ;
  rdfs:comment "Immunization with a recombinant yeast-expressed Plasmodium falciparum merozoite surface protein 3 (MSP3) protected Aotus nancymai monkeys against a virulent challenge infection [PubMed: 19073223]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0000675 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae vaccine" ;
  rdfs:comment "a Streptococcal vaccine that is used against S. pneumoniae infection, which causes pneumococcal diseases. " ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000772 .

obo:VO_0007531 a rdfs:Class ;
  rdfs:label "Murine TYRP2 plasmid DNA vaccine" ;
  rdfs:comment "A plasmid DNA vaccine encoding the mouse tumor associated antigen tyrosinase-related protein-2 (TYRP2) with potential immunostimulating and antineoplastic activities. Upon administration, murine TYRP2 plasmid DNA vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing TYRP2; this vaccine may also induce an immune response against tyrosinase-related protein-1 (TYRP1). TYRP2 and TYRP1, melanosomal membrane glycoproteins upregulated in melanoma cells, are involved in melanin synthesis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:OBI_0500000 a rdfs:Class ;
  rdfs:label "study design"@en ;
  rdfs:comment "A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:VO_0020461 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1 by Waymade" .

obo:VO_0018338 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT Injection [RabAvert] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018299 .

obo:VO_0018887 a rdfs:Class ;
  rdfs:label "influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0005367 a rdfs:Class ;
  rdfs:label "MPL + TDM vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant that is monophosphoryl lipid A (detoxified endotoxin) from S. minnesota (MPL) and synthetic trehalose dicorynomycolate (TDM) in 2% oil (squalene)-Tween 80-water." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0001882 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Hardjo-Pomona Bacterin (USDA: 4069.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002335 .

obo:VO_0020936 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0020929 .

obo:VO_0016572 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Hepatitis B Surface Antigen Vaccine Injectable Solution [Twinrix Paediatric]" ;
  rdfs:subClassOf obo:VO_0016579 .

obo:VO_0011562 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae Omp26 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012185 .

obo:VO_0017660 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Tetamun]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0011405 a rdfs:Class ;
  rdfs:label "Herpes simplex virus type 2 DNA vaccine encoding ICP27" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0011050 a rdfs:Class ;
  rdfs:label "Tax" ;
  rdfs:comment "A DNA vaccination trial was performed on sheep to determine whether vaccination with bovine leukemia virus (BLV) transactivator Tax DNA is effective against BLV infection.  Results showed higher levels of virus titers in control sheep than those in Tax-vaccinated sheep. Higher levels of IFN-gamma mRNA expression have been demonstrated in vaccinated sheep after the challenge. These results suggested that Th1 type immune response induced by Tax DNA vaccine inhibited BLV propagation in vaccinated sheep at the early phase of infection [PubMed: 14665749]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010797 .

obo:VO_0003614 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2014-2015 Formula Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003612 .

obo:VO_0010311 a rdfs:Class ;
  rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003501 , obo:VO_0010299 .

obo:VO_0001101 a rdfs:Class ;
  rdfs:label "persons aged 25--64 years with  medical conditions at higher risk for influenza-related complications" ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:DOID_14067 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum malaria"@en ;
  rdfs:comment "A malaria described as a severe form of the disease caused by a parasite Plasmodium falciparum, which is marked by irrregular recurrence of paroxysms and prolonged or continuous fever."@en ;
  rdfs:subClassOf obo:DOID_12365 .

obo:VO_0005068 a rdfs:Class ;
  rdfs:label "pBC12B1 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pBC12B1.  This plasmid is a eukaryotic expression vector." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000516 a rdfs:Class ;
  rdfs:label "human protein" ;
  rdfs:comment "a protein from human" ;
  rdfs:subClassOf obo:PR_000000001 .

obo:NCBITaxon_327045 a rdfs:Class ;
  rdfs:label "Orthoretrovirinae" ;
  rdfs:subClassOf obo:NCBITaxon_2732514 .

obo:VO_0019787 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0017956 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.5 MG / meningococcal group C polysaccharide 0.5 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017821 .

obo:VO_0002578 a rdfs:Class ;
  rdfs:label "purN from Burkholderia pseudomallei" ;
  rdfs:comment "Although 30:93a purN -immunized mice were challenged with a 10-fold higher dose of WT E8, mice were strongly protected and showed no signs of clinical illness until the experiment was terminated" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001411 .

obo:VO_0004419 a rdfs:Class ;
  rdfs:label "Hirame rhabdovirus DNA vaccine pHRV-G encoding HIRRV and VHSV G protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002455 .

obo:VO_0002276 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine-Mycoplasma Gallisepticum Bacterin (USDA: 48B6.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002454 , obo:VO_0007748 .

obo:VO_0019866 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0019167 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019457 .

obo:VO_0021097 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020495 .

obo:VO_0001442 a rdfs:Class ;
  rdfs:label "Pseudorabies virus gene" ;
  rdfs:comment "A viral gene that is from Pseudorabies virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0002607 a rdfs:Class ;
  rdfs:label "lpd from Mycoplasma gallisepticum" ;
  rdfs:comment "An lpd mutant is highly attenuated in chickens and induces significant protection from challenge with wild type M. gallisepticum" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001416 .

obo:VO_0020574 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Influsplit] Box of 10" ;
  rdfs:subClassOf obo:VO_0020573 , obo:VO_0020603 , obo:VO_0020870 .

obo:VO_0018683 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML Oral Suspension [Rotarix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018682 , obo:VO_0018684 .

obo:VO_0019874 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Flulaval 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019873 , obo:VO_0020340 .

obo:VO_0016144 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0001426 a rdfs:Class ;
  rdfs:label "Yersinia pestis gene" ;
  rdfs:comment "A bacterial gene that is from Yersinia pestis." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0017414 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Adt Vaccine]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0018795 .

obo:VO_0018350 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003338 .

obo:VO_0004987 a rdfs:Class ;
  rdfs:label "Comirnaty vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine formed from a lipid nanoparticle-formulated trimerized SARS-CoV-2 receptor-binding domain" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0017580 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0017555 .

obo:VO_0004038 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae NucA Protein vaccine" ;
  rdfs:subClassOf obo:VO_0012185 .

obo:VO_0018848 a rdfs:Class ;
  rdfs:label "BCG, live, Tice strain 50 MG" ;
  rdfs:subClassOf obo:VO_0019465 .

obo:VO_0001570 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001501 .

obo:NCBITaxon_487 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis" ;
  rdfs:subClassOf obo:NCBITaxon_206351 .

obo:VO_0004304 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pBK-SFV-HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0020145 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML [Menactra]" ;
  rdfs:subClassOf obo:VO_0000071 , obo:VO_0000561 .

obo:VO_0016900 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Boostrix]" ;
  rdfs:subClassOf obo:VO_0016899 , obo:VO_0017277 .

obo:VO_0000461 a rdfs:Class ;
  rdfs:label "avian influenza vaccine" ;
  rdfs:comment "An influenza vaccine for avian use" ;
  rdfs:subClassOf obo:VO_0000642 , obo:VO_0001461 .

obo:VO_0004225 a rdfs:Class ;
  rdfs:label "BHV1 gD subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000987 .

obo:VO_0000317 a rdfs:Class ;
  rdfs:label "Psin DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0010845 a rdfs:Class ;
  rdfs:label "Nipah virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0018634 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 12 BAU/ML Injectable Suspension [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0018632 , obo:VO_0018633 , obo:VO_0018638 .

obo:VO_0004134 a rdfs:Class ;
  rdfs:label "Coxevac vaccine" ;
  rdfs:subClassOf obo:VO_0000463 .

obo:VO_0000423 a rdfs:Class ;
  rdfs:label "escheriosome-mediated delivery of Brucella abortus L7/L12 vaccine" ;
  rdfs:subClassOf obo:VO_0001221 .

obo:VO_0007296 a rdfs:Class ;
  rdfs:label "Autologous GM-CSF-secreting Lethally Irradiated Colorectal Cancer Cell Vaccine" ;
  rdfs:comment "A lethally irradiated, autologous colorectal cancer vaccine consisting of patient-specific colorectal cancer cells genetically modified to secrete the cytokine granulocyte-macrophage colony stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Upon vaccination, the autologous GM-CSF-secreting lethally irradiated colorectal cancer cell vaccine releases GM-CSF. In turn, GM-CSF may increase the body's immune response against tumor cells by promoting the maturation and activation of dendritic cells (DCs), and enhancing tumor-specific antigen presentation to both B- and T-cells, which leads to better recognition of tumors by the immune system. In addition, GM-CSF promotes antibody-dependent cellular cytotoxicity (ADCC), and increases interleukin-2-mediated lymphokine-activated killer cell function." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0004146 a rdfs:Class ;
  rdfs:label "Brucella ovis microparticle subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0002925 .

obo:VO_0015724 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [H B Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015574 , obo:VO_0015794 .

obo:VO_0016379 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1 by Waymade" ;
  rdfs:subClassOf obo:VO_0015941 .

obo:VO_0018674 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 Powder for Oral Suspension" ;
  rdfs:subClassOf obo:VO_0018672 , obo:VO_0018698 .

obo:VO_0004544 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae DNA vaccine pcDNA-apxIA/pcDNA-apxIIA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001130 .

obo:VO_0016380 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015942 .

obo:VO_0016833 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016762 .

obo:VO_0001725 a rdfs:Class ;
  rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.04)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000620 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0003010 a rdfs:Class ;
  rdfs:label "obsolete P. yoelii p36/p52 mutant vaccine" ;
  rdfs:comment "A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites" .

obo:VO_0016826 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0016734 , obo:VO_0016775 .

obo:NCBITaxon_329639 a rdfs:Class ;
  rdfs:label "Canine minute virus" ;
  rdfs:subClassOf obo:NCBITaxon_40119 .

obo:VO_0017121 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017579 .

obo:VO_0010354 a rdfs:Class ;
  rdfs:label "PENBRAYA vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0010444 .

obo:VO_0007256 a rdfs:Class ;
  rdfs:label "Anti-CD19/CD3 Tetravalent Antibody AFM11 Vaccine" ;
  rdfs:comment "An anti-CD19/anti-CD3 bispecific tetravalent antibody with potential immunostimulatory and antineoplastic activities. Anti-CD19/CD3 tetravalent antibody AFM11 possesses two antigen-recognition and binding sites, one for the CD3 complex, a group of T-cell surface glycoproteins that complex with the T-cell receptor (TCR), and one for CD19, a tumor-associated antigen (TAA) overexpressed on the surface of B-cells. Upon bolus infusion of AFM11, this bispecific antibody binds to CD3-expressing T-cells and CD19-expressing cancer cells, thereby crosslinking CD19-expressing tumor B-cells and cytotoxic T-lymphocytes (CTLs). This may result in a potent CTL-mediated cell lysis of CD19-expressing B-lymphocytes. CD19, a B-cell specific membrane antigen, is expressed during both B-cell development and B-cell malignant growth." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0001546 a rdfs:Class ;
  rdfs:label "Feline Leukemia Killed Virus Vaccine (USDA: 1555.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0000843 , obo:VO_0007748 .

obo:VO_0018231 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0018228 .

obo:VO_0004716 a rdfs:Class ;
  rdfs:label "rMCMV-TRP2 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0007092 a rdfs:Class ;
  rdfs:label "NA-17/MAGE-3.A2/NY-ESO-1 peptide vaccine" ;
  rdfs:comment "A peptide cancer vaccine consisting of peptides derived from the melanoma antigen NA-17, the human leukocyte antigen HLA-A2-restricted human melanoma antigen 3 (MAGE-3.A2) and the cancer-testis antigen (NY-ESO-1), with potential immunostimulating and antineoplastic activities. Upon administration, the NA-17/MAGE-3.A2/NY-ESO-1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing NA-17, MAGE-3.A2 and NY-ESO-1, resulting in tumor cell lysis. The tumor-associated antigens (TAAs) NA-17, MAGE-3.A2 and NY-ESO-1 are overexpressed in a variety of cancer cell types." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0010983 a rdfs:Class ;
  rdfs:label "GNA1030" ;
  rdfs:comment "Protective antigen as shown in some assays [PubMed: 16825336]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0003479 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/60/2008 antigen" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:VO_0020948 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0000508 a rdfs:Class ;
  rdfs:label "Diphtheria toxoid vaccine" ;
  rdfs:comment "a diphtheria vaccine that uses diphtheria toxoid" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000735 .

obo:VO_0003839 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [PEDIARIX]" ;
  rdfs:subClassOf obo:VO_0003838 .

obo:VO_0005012 a rdfs:Class ;
  rdfs:label "pLXSHD DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pLXSHD.  This plasmid has a murine leukemia virus enhancer-promoter LTR." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003312 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 5 vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003255 .

obo:VO_0003181 a rdfs:Class ;
  rdfs:label "Measles virus vaccine foreign to USA" ;
  rdfs:comment "A measles virus vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0003444 , obo:VO_0010441 .

obo:VO_0000490 a rdfs:Class ;
  rdfs:label "immunization" ;
  rdfs:comment "Process that results in an adaptive immune response to one or more antigens." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0016317 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015932 .

obo:VO_0000429 a rdfs:Class ;
  rdfs:label "phase 3 vaccine trial" ;
  rdfs:comment "A vaccine clinical trial that takes the trial to a large-scale safety and efficacy study in a relevant patient population, usually in excess of 3,000." ;
  rdfs:subClassOf obo:VO_0000596 .

obo:VO_0018011 a rdfs:Class ;
  rdfs:label "poliomyelitis virus type 1 brunhilde" ;
  rdfs:subClassOf obo:VO_0003834 .

obo:PATO_0000169 a rdfs:Class ;
  rdfs:label "viability" ;
  rdfs:comment "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:VO_0018625 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injection [Jespect]" ;
  rdfs:subClassOf obo:VO_0018619 , obo:VO_0018624 , obo:VO_0018641 .

obo:VO_0010759 a rdfs:Class ;
  rdfs:label "Yersinia pestis protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0010435 a rdfs:Class ;
  rdfs:label "licensed human bordetella pertussis vaccine" ;
  rdfs:comment "Bordetella pertussis vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000765 .

obo:VO_0005503 a rdfs:Class ;
  rdfs:label "vaccine against disease" ;
  rdfs:comment "Vaccine that prevents or treats specific disease." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0007402 a rdfs:Class ;
  rdfs:label "hTERT mRNA/survivin peptide-double-loaded autologous dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine containing autologous dendritic cells (DCs) that are pulsed with mRNA encoding human telomerase reverse transcriptase (hTERT) and survivin peptide, with potential immunostimulatory and antineoplastic activities. Upon administration, hTERT mRNA/survivin peptide-double-loaded autologous dendritic cell vaccine may elicit an immune response against cancer cells expressing hTERT and survivin by activating cytotoxic T-cells (CTLs), natural killer cells (NKs), and B-lymphocytes. The tumor associated antigens (TAAs) hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types and play key roles in tumor cell growth and survival." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0016552 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016063 .

obo:VO_0002247 a rdfs:Class ;
  rdfs:label "Canine Distemper-Hepatitis-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 47P9.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002426 , obo:VO_0007748 .

obo:VO_0018223 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT Injectable Solution [Priorix] by GSK" ;
  rdfs:subClassOf obo:VO_0018222 .

obo:VO_0017469 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 1.5 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017466 .

obo:VO_0016399 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 25 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015958 , obo:VO_0015964 .

obo:VO_0004727 a rdfs:Class ;
  rdfs:label "ALVAC-HIV-2 vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0018146 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 100" ;
  rdfs:subClassOf obo:VO_0018144 , obo:VO_0018156 .

obo:VO_0018000 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018046 .

obo:VO_0002865 a rdfs:Class ;
  rdfs:label "CVD 908-htrA vaccine" ;
  rdfs:comment "Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ;
  rdfs:subClassOf obo:VO_0000671 .

obo:VO_0010058 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi PkCSP" ;
  rdfs:comment "A PkCSP protein that is part of Plasmodium knowlesi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015472 .

obo:VO_0004751 a rdfs:Class ;
  rdfs:label "rFPV-NDV-H/F vaccine" ;
  rdfs:subClassOf obo:VO_0001222 .

obo:VO_0019747 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0017799 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000765 , obo:VO_0010435 .

obo:VO_0007708 a rdfs:Class ;
  rdfs:label "neoantigen DNA vaccine" ;
  rdfs:comment "A cancer vaccine that may enhance anti-tumor immune response in Renal Cell Carcinoma in combination with checkpoint inhibitors ipilimumab (anti-CTLA-4 antibody) and nivolumab (anti-PD-1 antibody)." ;
  rdfs:subClassOf obo:VO_0005494 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0020802 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 UNT Injectable Solution [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020800 , obo:VO_0020801 , obo:VO_0020805 .

obo:DOID_0050117 a rdfs:Class ;
  rdfs:label "disease by infectious agent"@en ;
  rdfs:comment "A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions."@en ;
  rdfs:subClassOf obo:DOID_4 .

obo:NCBITaxon_1716 a rdfs:Class ;
  rdfs:label "Corynebacterium" ;
  rdfs:subClassOf obo:NCBITaxon_85007 .

obo:VO_0003603 a rdfs:Class ;
  rdfs:label "influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010316 , obo:VO_0010415 .

obo:VO_0004771 a rdfs:Class ;
  rdfs:label "NYVAC-EHV-1- vP1014 vaccine" ;
  rdfs:subClassOf obo:VO_0001486 .

obo:VO_0016687 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0015667 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015595 .

obo:VO_0017168 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017163 , obo:VO_0017185 , obo:VO_0017619 .

obo:NCBITaxon_10993 a rdfs:Class ;
  rdfs:label "Birnaviridae" ;
  rdfs:subClassOf obo:NCBITaxon_2732396 .

obo:VO_0000437 a rdfs:Class ;
  rdfs:label "Moraxella bovis vaccine" ;
  rdfs:comment "Vaccine that protects against Moraxella bovis infection. Moraxella bovis is a Gram-negative, aerobic, oxidase-positive diplococcus that is implicated in infectious bovine keratoconjunctivitis, an eye disease of cattle, also colloquially known as Pink Eye." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0004920 a rdfs:Class ;
  rdfs:label "vaccine specific Th2 immune response indicated by IgG1  production" ;
  rdfs:comment "vaccine-induced T-helper 2 type immune response that is indicated by the presence of IgG1 production" ;
  rdfs:subClassOf obo:VO_0000101 .

obo:VO_0005421 a rdfs:Class ;
  rdfs:label "GLA-SLQ vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002589 a rdfs:Class ;
  rdfs:label "rfaL from Escherichia coli" ;
  rdfs:comment "Deletion of waaL results in a strain that stimulates enhanced urothelial cytokine secretion, which is an enhanced innate immune response. Inoculation with the vaccine strain protected mice against challenge with a broad range of clinical uropathogenic E. coli isolates and produced immunity that lasted >=8 weeks." ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000161 .

obo:BFO_0000030 a rdfs:Class ;
  rdfs:label "object"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0020766 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020758 , obo:VO_0020806 .

obo:VO_0016568 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Injectable Suspension [Twinrix Adult]" ;
  rdfs:subClassOf obo:VO_0016578 .

obo:VO_0010430 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2022" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:NCBITaxon_235 a rdfs:Class ;
  rdfs:label "Brucella abortus" ;
  rdfs:subClassOf obo:NCBITaxon_234 .

obo:VO_0001706 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.14)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0005007 a rdfs:Class ;
  rdfs:label "p188 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label p188.  This plasmid is a replication-defective derivative of pP1/H7." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0017200 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 100" ;
  rdfs:subClassOf obo:VO_0017188 , obo:VO_0017638 .

obo:VO_0017591 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML [T Wellcovax]" ;
  rdfs:subClassOf obo:VO_0017682 .

obo:VO_0007306 a rdfs:Class ;
  rdfs:label "autologous melanoma Lysate/KLH-pulsed autologous dendritic cell vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous melanoma cells containing tumor associated antigens (TAAs) and conjugated to the immunostimulant Keyhole limpet hemocyanin (KLH), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate/KLH-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against melanoma cells, which may result in melanoma cell lysis. KLH is an immunogenic carrier and serves as an immunostimulant to improve antigenic immune recognition and T-cell responses and can be used to evaluate vaccine efficacy." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0020134 a rdfs:Class ;
  rdfs:label "mumps virus vaccine live, Jeryl Lynn strain 40000 UNT/ML [Mumpsvax]" ;
  rdfs:subClassOf obo:VO_0000074 , obo:VO_0015057 .

obo:VO_0002384 a rdfs:Class ;
  rdfs:label "chicken Bursal Disease-Newcastle Disease-Reovirus Vaccine" ;
  rdfs:subClassOf obo:VO_0002365 , obo:VO_0002385 .

obo:DOID_1115 a rdfs:Class ;
  rdfs:label "sarcoma"@en ;
  rdfs:comment "A cell type cancer that has_material_basis_in abnormally proliferating cells derives from embryonic mesoderm."@en ;
  rdfs:subClassOf obo:DOID_0050687 .

obo:VO_0016959 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0016956 , obo:VO_0017419 .

obo:VO_0019378 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000946 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0010221 a rdfs:Class ;
  rdfs:label "Td(adult) unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003396 , obo:VO_0010436 .

obo:VO_0016276 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015924 .

obo:VO_0001076 a rdfs:Class ;
  rdfs:label "recombinant homologous vector vaccine" ;
  rdfs:comment "a recombinant vector vaccine that uses a homologous vector, i.e., when the target species of the vaccine is a natural host for the vector." ;
  rdfs:subClassOf obo:VO_0000484 .

obo:VO_0017693 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Pediacel] Box of 20" ;
  rdfs:subClassOf obo:VO_0017690 , obo:VO_0017705 , obo:VO_0017746 .

obo:VO_0001613 a rdfs:Class ;
  rdfs:label "Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.21)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0016407 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0000967 a rdfs:Class ;
  rdfs:label "rBCG-Stx3B vaccine" ;
  rdfs:subClassOf obo:VO_0000966 .

obo:VO_0001792 a rdfs:Class ;
  rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.03)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001456 , obo:VO_0007748 .

obo:OPL_0000320 a rdfs:Class ;
  rdfs:label "Mammalia blood" ;
  rdfs:comment "Blood that is part of or originated from a mammalia." ;
  rdfs:subClassOf obo:OPL_0000310 , obo:UBERON_0000178 .

obo:NCBITaxon_5861 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii" ;
  rdfs:subClassOf obo:NCBITaxon_418101 .

obo:VO_0000784 a rdfs:Class ;
  rdfs:label "VRP expressing VP40 vaccine" ;
  rdfs:comment "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP40 protein." ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0002726 a rdfs:Class ;
  rdfs:label "G protein from Human metapneumovirus" ;
  rdfs:comment "A G mutant is attenuated in African green monkeys and induces protection from challenge with wild type HMPV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001438 .

obo:VO_0016512 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Gen Vax] Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0015982 .

obo:VO_0002257 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4845.33)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002429 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0007646 a rdfs:Class ;
  rdfs:label "Multipeptide melanoma vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:NCBITaxon_629 a rdfs:Class ;
  rdfs:label "Yersinia <enterobacteria>" ;
  rdfs:subClassOf obo:NCBITaxon_1903411 .

obo:VO_0010890 a rdfs:Class ;
  rdfs:label "MOMP" ;
  rdfs:comment "Female BALB/c mice were immunized with chlamydial major outer membrane protein (MOMP) mixed with cholera toxin and CpG oligodeoxynucleotide adjuvants by either the IN or TCI routes.  Both intranasal and transcutaneous immunization protected mice against respiratory challenge with Chlamydia [PubMed: 16153755]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010795 .

obo:VO_0003429 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0015753 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015813 .

obo:VO_0004404 a rdfs:Class ;
  rdfs:label "Autoimmune diabetes DNA vaccine pCMV-1/rGAD65 encoding GAD" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002811 .

obo:VO_0017551 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML [Repevax]" ;
  rdfs:subClassOf obo:VO_0017548 .

obo:NCBITaxon_10514 a rdfs:Class ;
  rdfs:label "Canine adenovirus 2" ;
  rdfs:subClassOf obo:NCBITaxon_10537 .

obo:VO_0018922 a rdfs:Class ;
  rdfs:label "influenza A virus A/Kansas/14/2017 (H3N2) antigen" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0011535 a rdfs:Class ;
  rdfs:label "Measles Virus vaccine VVN" ;
  rdfs:subClassOf obo:VO_0000654 .

obo:VO_0005514 a rdfs:Class ;
  rdfs:label "CpG 1018 vaccine adjuvant" ;
  rdfs:comment "Short class B CpG-containing sequence with phosphorothioate-linked nucleotides that is able to induce a Th1-biased response." ;
  rdfs:subClassOf obo:VO_0006109 .

obo:VO_0003955 a rdfs:Class ;
  rdfs:label "vibrio cholerae CVD 103-HGR strain live antigen" ;
  rdfs:comment "CUI: C4291328" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0007179 a rdfs:Class ;
  rdfs:label "VHL2 (Y12M) Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL2 (Y12M) peptide is a point mutation variant (from tyrosine to methionine at amino acid position 12) of the VHL protein. Vaccination with this peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0004127 a rdfs:Class ;
  rdfs:label "Irradiated MBGV antigen vaccine" ;
  rdfs:subClassOf obo:VO_0012163 .

obo:VO_0016557 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0000745 , obo:VO_0001214 .

obo:VO_0019325 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.12 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.12 MG/ML Prefilled Syringe [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:NCBITaxon_9935 a rdfs:Class ;
  rdfs:label "Ovis" ;
  rdfs:subClassOf obo:NCBITaxon_9963 .

obo:VO_0010294 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant NADA fusion protein antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0020090 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine B/Brisbane/60/2008 antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0003523 .

obo:VO_0002488 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Leptospira Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002338 , obo:VO_0002352 .

obo:VO_0017540 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution [Tetamun] Box of 1" ;
  rdfs:subClassOf obo:VO_0017539 , obo:VO_0017542 .

obo:VO_0005812 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii LDH1 and LDH2 mutant vaccine" ;
  rdfs:comment "A Live attenuated vaccine with LDH1 and LDH2 mutant that immunizes against Toxoplasma gondii trypmastigote." ;
  rdfs:subClassOf obo:VO_0000994 .

obo:VO_0020892 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Grippe-Impfstoff Csl]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0018850 a rdfs:Class ;
  rdfs:label "influenza A virus A/Indonesia/05/2005 (H5N1) antigen 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010324 , obo:VO_0010415 .

obo:VO_0011325 a rdfs:Class ;
  rdfs:label "PEP1" ;
  rdfs:comment "Groups of C57BL/6 mice (20 per group) vaccinated with rPep1 (1 mug per dose) plus adjuvant and challenged with an intranasal inoculum began to die at about 14 to 16 days but then showed significantly greater survival than the control mice [PubMed: 16369008]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010853 .

obo:VO_0003326 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 20 vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003226 .

obo:VO_0001843 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 15B5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0002433 , obo:VO_0007748 .

obo:VO_0003406 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 8 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0001888 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002338 .

obo:VO_0007285 a rdfs:Class ;
  rdfs:label "autologous dendritic cell-Adenovirus P53 vaccine" ;
  rdfs:comment "An autologous vaccine composed of dendritic cells (DC) that have been transduced with a p53 tumor suppressor gene-modified virus. When the autologous dendritic cell-adenovirus p53 vaccine is administered, the host cytotoxic T lymphocytes (CTL) are directed against p53-positive tumor cells, which may result in tumor cell death and decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0002839 a rdfs:Class ;
  rdfs:label "E. coli rfaL mutant vaccine" ;
  rdfs:comment "Deletion of waaL results in a strain that stimulates enhanced urothelial cytokine secretion, which is an enhanced innate immune response. Inoculation with the vaccine strain protected mice against challenge with a broad range of clinical uropathogenic E. coli isolates and produced immunity that lasted >= 8 weeks." ;
  rdfs:subClassOf obo:VO_0000962 .

obo:VO_0019902 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluarix 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020318 .

obo:VO_0001004 a rdfs:Class ;
  rdfs:label "pcDNA3.1/V5-His DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1/V5-His.  This plasmid has a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0004750 a rdfs:Class ;
  rdfs:label "rFPV-IBDV-VP 2.4.3 vaccine" ;
  rdfs:subClassOf obo:VO_0001497 .

obo:VO_0004801 a rdfs:Class ;
  rdfs:label "BDES-PfCSP vaccine (baculovirus dual expression system)" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0002217 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Live Canarypox Vector Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.R1)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002404 , obo:VO_0007748 .

obo:VO_0016537 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0018056 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 100" ;
  rdfs:subClassOf obo:VO_0018053 , obo:VO_0018076 , obo:VO_0018146 .

obo:VO_0018093 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018228 .

obo:VO_0001336 a rdfs:Class ;
  rdfs:label "AS-2 vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant and is based on the combination of Monophosphoryl Lipid A(MPL), QS21 (a purified fraction of Saponin extracted from Quillarja Saponaria), and a proprietary oil in water emulsion." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0018578 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML Oral Suspension" ;
  rdfs:subClassOf obo:VO_0018681 .

obo:VO_0004595 a rdfs:Class ;
  rdfs:label "P. knowlesi DNA vaccine encoding PkCSP, PkSSP2, PkAMA1, and PkMSP1p42" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000761 .

obo:VO_0003405 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 8 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0015763 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015583 , obo:VO_0015820 .

obo:VO_0019178 a rdfs:Class ;
  rdfs:label "0.5 ML hepatitis B surface antigen vaccine 0.005 MG/ML Prefilled Syringe [Recombivax]" ;
  rdfs:subClassOf obo:VO_0015485 , obo:VO_0019524 .

obo:VO_0001807 a rdfs:Class ;
  rdfs:label "Pseudorabies Modified Live Virus Vaccine (USDA: 1891.22)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000750 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0007596 a rdfs:Class ;
  rdfs:label "obsolete CVB4/p24(73(3)) vaccine" ;
  rdfs:comment "Recorded as licensed cancer vaccine without reference. Based on the vaccine name, it is not correct, see term:VO:0004719." .

obo:VO_0011288 a rdfs:Class ;
  rdfs:label "P4 from Leishmania amazonensis" ;
  rdfs:comment "Susceptible BALB/c mice were immunized with the DNA encoding P4 alone, P4/IL-12, or P4/HSP70 prior to challenge with L. amazonensis promastigotes.  Mice immunized with P4 alone had a delayed onset of lesion development and significantly smaller lesions than the infection control group at 11 weeks postinfection (P < 0.05).  P4/IL-12 immunized animals showed no sign of lesion development in three independent experiments (P < 0.01).  Our results indicate that different vaccine combinations, including DNA encoding P4, HSP70, or IL-12, can provide significant protection against both Old World and New World cutaneous leishmaniasis [PubMed: 14573646]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010837 .

obo:VO_0015803 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0015493 .

obo:VO_0015147 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine, Inactivated 320 UNT/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution [Vivaxim] by Sanofi" ;
  rdfs:subClassOf obo:VO_0015146 .

obo:VO_0016325 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 3 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015937 .

obo:VO_0000289 a rdfs:Class ;
  rdfs:label "host response to vaccine adjuvant" ;
  rdfs:comment "a process that specifies host response to a vaccine adjuvant." ;
  rdfs:subClassOf obo:VO_0000290 .

obo:VO_0006002 a rdfs:Class ;
  rdfs:label "cholera vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010455 .

obo:VO_0019943 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluarix 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020317 .

obo:VO_0020664 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] by Sanofi" ;
  rdfs:subClassOf obo:VO_0020657 .

obo:VO_0020759 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020758 .

obo:NCBITaxon_10390 a rdfs:Class ;
  rdfs:label "Gallid alphaherpesvirus 2" ;
  rdfs:subClassOf obo:NCBITaxon_180252 .

obo:VO_0016657 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0005236 a rdfs:Class ;
  rdfs:label "PTX-COVID19-B vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine by Providence Therapeutics" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0017901 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML Prefilled Syringe [ActHIB]" ;
  rdfs:subClassOf obo:VO_0017831 .

obo:VO_0019157 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.006 MG/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000946 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0012397 a rdfs:Class ;
  rdfs:label "Emm1" ;
  rdfs:comment "Mice were intranasally immunized with diphtheria toxoid (DT) conjugated polypeptides encompassing a conformational-constrained B cell epitope of the M1 protein (J8). Vaccinated mice were challenged 10 days after the last boost by the intranasal route. Animals had 60% protection against challenge [PubMed: 16828529]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012357 .

obo:VO_0005117 a rdfs:Class ;
  rdfs:label "Ad5.MERS-S vaccine" ;
  rdfs:comment "A MERS recombinant vector vaccine made of a recombinant adenoviral vector encoding the full-length MERS-CoV S protein (Ad5.MERS-S)" ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0017994 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injectable Solution [Ipol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017993 , obo:VO_0017995 , obo:VO_0018035 .

obo:VO_0000927 a rdfs:Class ;
  rdfs:label "human serum cell culture residual in vaccine" ;
  rdfs:comment "a cell culture residual in vaccine that is human serum." ;
  rdfs:subClassOf obo:VO_0000856 .

obo:NCBITaxon_3344809 a rdfs:Class ;
  rdfs:label "Herpes Simplexvirus" ;
  rdfs:subClassOf obo:NCBITaxon_10294 .

obo:VO_0001752 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine (USDA: 18P5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012180 .

obo:VO_0017788 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0017779 .

obo:VO_0005288 a rdfs:Class ;
  rdfs:label "INI-4001 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0021085 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010447 .

obo:VO_0015612 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax]" ;
  rdfs:subClassOf obo:VO_0015485 , obo:VO_0015563 .

obo:VO_0004908 a rdfs:Class ;
  rdfs:label "COVID-19 vaccine" ;
  rdfs:comment "A coronavirus vaccine against the infection of SARS-CoV-2 (cause of COVID-19)" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0004897 .

obo:NCBITaxon_1206794 a rdfs:Class ;
  rdfs:label "Ecdysozoa" ;
  rdfs:subClassOf obo:NCBITaxon_33317 .

obo:VO_0003175 a rdfs:Class ;
  rdfs:label "Adenovirus Type 4 vaccine" ;
  rdfs:comment "An oral vaccine against adenovirus serotype 4." ;
  rdfs:subClassOf obo:VO_0000037 , obo:VO_0000455 , obo:VO_0000635 , obo:VO_0001220 .

obo:VO_0005018 a rdfs:Class ;
  rdfs:label "pCMV/myc/ER DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCMV/myc/ER.  This plasmid is 5066 base pairs in length and contains a CMV promoter and ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001509 a rdfs:Class ;
  rdfs:label "Feline calicivirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Feline calicivirus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0010942 a rdfs:Class ;
  rdfs:label "FlaA from C. jejuni NCTC 11168" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010765 .

obo:VO_0004157 a rdfs:Class ;
  rdfs:label "Yersinia pestis YscF protein vaccine" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0002810 a rdfs:Class ;
  rdfs:label "Brucella abortus and Brucella melitensis mutants with unmarked deletion of asp24, virB2, or manBA vaccine" ;
  rdfs:comment "Unmarked rough B. abortus and B. melitensis deletion mutants of manBA (including manA and manB) were attenuated. These mutants provided protection against virulent Brucella challenge in mice" ;
  rdfs:subClassOf obo:VO_0001134 .

obo:VO_0007245 a rdfs:Class ;
  rdfs:label "ALVAC-ESO-1 vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) encoding the cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon administration, ALVAC-ESO-1 vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against NY-ESO-1-expressing cancer cells, which may result in the inhibition of tumor cell proliferation. NY-ESO-1, a tumor associated antigen (TAA), is found in normal testis and on the surface of various tumor cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:OPL_0000146 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum trophozoite" ;
  rdfs:comment "A Plasmodium falciparum is a feeding form. The trophozoite stage has only 1 nucleus. Depending on its location, it is either called hepatic or erythrocytic trophozoite." ;
  rdfs:subClassOf obo:NCBITaxon_5833 , obo:OPL_0000281 .

obo:VO_0003192 a rdfs:Class ;
  rdfs:label "Meningococcal Conjugate and Haemophilis B Vaccine" ;
  rdfs:comment "An active immunizing combination agent that is used to prevent infection caused by certain groups of meningococcal bacteria and Haemophilus influenza type b (Hib) bacteria." ;
  rdfs:subClassOf obo:VO_0000641 , obo:VO_0000662 , obo:VO_0003441 .

obo:VO_0004107 a rdfs:Class ;
  rdfs:label "BCG expressing MSP vaccine" ;
  rdfs:subClassOf obo:VO_0003130 .

obo:VO_0017741 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017770 , obo:VO_0017802 .

obo:VO_0016952 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0016951 , obo:VO_0017409 .

obo:VO_0003169 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Whole Cell Pertussis-Haemophilus b vaccine" ;
  rdfs:comment "A combination vaccine with whole cell that protects against diphtheria, tetanus, pertussis, and Haemophilus influenzae type B." ;
  rdfs:subClassOf obo:VO_0000942 .

obo:VO_0016911 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0016910 , obo:VO_0017292 .

obo:VO_0020095 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Wisconsin-1-2010-like virus 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003521 .

obo:VO_0020392 a rdfs:Class ;
  rdfs:label "typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0020279 , obo:VO_0020469 .

obo:NCBITaxon_9615 a rdfs:Class ;
  rdfs:label "Canis lupus familiaris" ;
  rdfs:subClassOf obo:NCBITaxon_9612 .

obo:NCBITaxon_314146 a rdfs:Class ;
  rdfs:label "Euarchontoglires" ;
  rdfs:subClassOf obo:NCBITaxon_1437010 .

obo:VO_0017602 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 80" ;
  rdfs:subClassOf obo:VO_0017597 , obo:VO_0017609 .

obo:DOID_11260 a rdfs:Class ;
  rdfs:label "rabies"@en ;
  rdfs:comment "A viral infectious disease that results in inflammation located in brain or located in spinal cord, has_material_basis_in Rabies virus, which is transmitted by bite of an infected animal, or transmitted by contact of mucous membranes with saliva of an infected animal. The infection has symptom fever, has symptom headache, has symptom prickling or itching sensation at the site of bite, has symptom anxiety, has symptom confusion, has symptom agitation, has symptom delirium, has symptom difficulty swallowing, has symptom hydrophobia, and has symptom paralysis."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0003015 a rdfs:Class ;
  rdfs:label "obsolete Toxoplasma gondii OMPDC/UP mutant vaccine" ;
  rdfs:comment "A UP mutant, in combination with an OMPDC mutation, is attenuated in mice and induces significant protection from wild type T. gondii" .

obo:VO_0010962 a rdfs:Class ;
  rdfs:label "Bp26" ;
  rdfs:comment "This is a protective antigen [PubMed: 17239499]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0010285 a rdfs:Class ;
  rdfs:label "vaccine challenge survival assay" ;
  rdfs:comment "An assay that measures the survival rate of organisms exposed to a pathogen." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0018715 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010451 .

obo:VO_0018703 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 TCID Injectable Suspension [RUDIVAX]" ;
  rdfs:subClassOf obo:VO_0018701 , obo:VO_0018702 , obo:VO_0018712 .

obo:VO_0001059 a rdfs:Class ;
  rdfs:label "Oka varicella vaccine vector" ;
  rdfs:comment "a poxvirus vaccine vector that uses an attenuated Oka varicella virus strain" ;
  rdfs:subClassOf obo:VO_0000283 .

obo:VO_0019828 a rdfs:Class ;
  rdfs:label "influenza A virus A/North Carolina/04/2016 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010431 .

obo:VO_0002614 a rdfs:Class ;
  rdfs:label "aroC from Salmonella Typhi" ;
  rdfs:comment "Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001419 .

obo:VO_0016147 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015886 .

obo:VO_0002906 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium asd/rfc mutant vaccine" ;
  rdfs:comment "An rfc mutant, in combination with an asd mutation, is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" .

obo:VO_0005801 a rdfs:Class ;
  rdfs:label "CTLVECNS vaccine" ;
  rdfs:comment "A Inactivated vaccine that immunizes against Toxoplasma gondii trypmastigote." ;
  rdfs:subClassOf obo:VO_0000994 .

obo:VO_0016725 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax]" ;
  rdfs:subClassOf obo:VO_0016710 , obo:VO_0016733 .

obo:VO_0017317 a rdfs:Class ;
  rdfs:label "Diphtheria Antitoxin / diphtheria toxoid vaccine, inactivated / influenza B virus antigen, Hong Kong 330-2001 / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017316 .

obo:NCBITaxon_5802 a rdfs:Class ;
  rdfs:label "Eimeria tenella" ;
  rdfs:subClassOf obo:NCBITaxon_5800 .

obo:VO_0007425 a rdfs:Class ;
  rdfs:label "multi-epitope folate receptor alpha peptide vaccine" ;
  rdfs:comment "Gene name: FOLR1" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0007491 a rdfs:Class ;
  rdfs:label "gp100:154-162 peptide vaccine" ;
  rdfs:comment "A peptide consisting of amino acid residues 154 through 162 of the melanoma-melanocyte antigen gp100. Vaccination with gp100:154-162 peptide may enhance tumor-specific T-cell immunity. gp100 antigen is a self-antigen expressed by melanocytes, pigmented retinal cells, and most melanoma lesions and is recognized via class I and II HLA-restricted mechanisms." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0018911 a rdfs:Class ;
  rdfs:label "influenza A virus A/Delaware/55/2019 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0001131 a rdfs:Class ;
  rdfs:label "replicating adenovirus accine vector" ;
  rdfs:comment "an adenovirus vaccine vector that is able to replicate." ;
  rdfs:subClassOf obo:VO_0000136 .

obo:CL_0000842 a rdfs:Class ;
  rdfs:label "mononuclear cell" ;
  rdfs:comment "A leukocyte with a single non-segmented nucleus in the mature form." ;
  rdfs:subClassOf obo:CL_0000226 , obo:CL_0000738 .

obo:VO_0004767 a rdfs:Class ;
  rdfs:label "rORFV-RHDV-VP60 vaccine" ;
  rdfs:subClassOf obo:VO_0001382 .

obo:VO_0001480 a rdfs:Class ;
  rdfs:label "African horse sickness virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with African horse sickness virus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003542 .

obo:VO_0011240 a rdfs:Class ;
  rdfs:label "US6 from Pseudorabies virus" ;
  rdfs:comment "The pseudorabies virus (PrV) DNA vaccine carrying the glycoprotein D (gD) gene delivered by E. coli was able to induce protective immune responses in mice against a lethal PrV challenge [PubMed: 11312026]. Immunization of mice with affinity-purified gD of Aujeszky's disease virus (ADV, Suid herpesvirus 1) induced a strong humoral immune response and protected mice against lethal ADV challenge [PubMed: 17601050]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010800 .

obo:DOID_4606 a rdfs:Class ;
  rdfs:label "bile duct cancer"@en ;
  rdfs:comment "A biliary tract cancer that is located_in the bile duct."@en ;
  rdfs:subClassOf obo:DOID_0080355 , obo:DOID_3118 .

obo:VO_0020851 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0020154 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen 0.12 MG/ML / Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen 0.12 MG/ML Prefilled Syringe [Trumenba]" ;
  rdfs:subClassOf obo:VO_0003081 , obo:VO_0020153 .

obo:VO_0002553 a rdfs:Class ;
  rdfs:label "bscN from Bordetella bronchiseptica" ;
  rdfs:comment "A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 x 105 CFU of RB50, the B. Bronchiseptica parent strain." ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001407 .

obo:VO_0002287 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.23)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002431 , obo:VO_0007748 .

obo:VO_0020852 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Afluria]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020888 .

obo:VO_0001065 a rdfs:Class ;
  rdfs:label "Neospora caninum vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0020585 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Preflucel] Box of 10 by Baxter" ;
  rdfs:subClassOf obo:VO_0020584 .

obo:VO_0000994 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0011267 a rdfs:Class ;
  rdfs:label "E1 glycoprotein" ;
  rdfs:comment "The monoclonal antibody against E1 glycoprotein protect outbred albino mice from lethal infection caused by the virulent strain Trd of the VEE virus [PubMed: 7529989]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010774 .

obo:VO_0016156 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0003846 a rdfs:Class ;
  rdfs:label "Ipol Injectable Product" ;
  rdfs:subClassOf obo:VO_0000054 .

obo:VO_0017005 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0017004 .

obo:VO_0000158 a rdfs:Class ;
  rdfs:label "pcDNA3.1 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0018573 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension [Stamaril] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018572 .

obo:GO_0002385 a rdfs:Class ;
  rdfs:label "mucosal immune response" ;
  rdfs:comment "An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract." ;
  rdfs:subClassOf obo:GO_0006955 .

obo:NCBITaxon_197913 a rdfs:Class ;
  rdfs:label "Gammainfluenzavirus" ;
  rdfs:subClassOf obo:NCBITaxon_11308 .

obo:VO_0004590 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii DNA vaccine encoding PySSP2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002514 .

obo:VO_0020068 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Afluria 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020299 .

obo:VO_0020855 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Begripal] Box of 10" ;
  rdfs:subClassOf obo:VO_0020854 , obo:VO_0020884 .

obo:VO_0003619 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Fluzone Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003616 .

obo:VO_0018743 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Delayed Release Oral Capsule" ;
  rdfs:subClassOf obo:VO_0018715 .

obo:CL_0002242 a rdfs:Class ;
  rdfs:label "nucleate cell" ;
  rdfs:comment "A cell containing at least one nucleus." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:VO_0020360 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML [Typherix]" ;
  rdfs:subClassOf obo:VO_0003855 , obo:VO_0010744 .

obo:VO_0001788 a rdfs:Class ;
  rdfs:label "Pacheco's Disease Killed Virus Vaccine (USDA: 18C5.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0000712 , obo:VO_0001473 , obo:VO_0001518 , obo:VO_0007748 .

obo:VO_0003940 a rdfs:Class ;
  rdfs:label "Human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine" ;
  rdfs:subClassOf obo:VO_0003303 .

obo:VO_0010359 a rdfs:Class ;
  rdfs:label "SPIKEVAX vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 , obo:VO_0005265 .

obo:VO_0017436 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.02 MG/ML [Hiberix]" ;
  rdfs:subClassOf obo:VO_0010715 , obo:VO_0017435 .

obo:VO_0019839 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003708 .

obo:VO_0017613 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0017590 , obo:VO_0017610 .

obo:VO_0003995 a rdfs:Class ;
  rdfs:label "Boostrix Injectable Product" ;
  rdfs:subClassOf obo:VO_0000015 .

obo:VO_0001371 a rdfs:Class ;
  rdfs:label "inactivated vaccine preparation using H2O2 inactivation" ;
  rdfs:comment "A vaccine prepraration process that is performed by H2O2 inactivation of virulent pathogen." ;
  rdfs:subClassOf obo:VO_0000178 .

obo:VO_0018049 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Vaccine 35000 PFU/ML / Rubella virus 1400 PFU/ML / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0018048 , obo:VO_0018138 .

obo:VO_0007476 a rdfs:Class ;
  rdfs:label "Gag:267-274 peptide vaccine" ;
  rdfs:comment "A cancer vaccine containing of a synthetic form of the renal cell carcinoma (RCC)-associated antigen G250 with potential antineoplastic activity. Vaccination with G250 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the G250 antigen, resulting in decreased tumor growth. Found in the majority of renal cell carcinomas, G250 is a cell surface tumor-associated antigen (TAA) that contains an HLA-A2.1-restricted epitope that is recognized by CTLs." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0006093 a rdfs:Class ;
  rdfs:label "CPDI-02 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is a peptide which is able to induce Th1/Th2/Th17 immune responses through the mechanism of selectively activates C5aR1 on mononuclear phagocytes vs neutrophils." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0015038 a rdfs:Class ;
  rdfs:label "Gardasil 9 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003075 .

obo:VO_0000415 a rdfs:Class ;
  rdfs:label "vaccine additive role" ;
  rdfs:comment "A role inheres in a material entity, that has been added into a vaccine's formulation by the manufacture for a specific purpose. For example: adjuvant to enhance the effect of immunogen, perservatives, stablizers and those materials added for affecting PH and isotonicity." ;
  rdfs:subClassOf obo:VO_0000617 .

obo:VO_0001611 a rdfs:Class ;
  rdfs:label "Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.1M)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0017829 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML [Meningitec]" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0010724 , obo:VO_0017877 .

obo:VO_0010025 a rdfs:Class ;
  rdfs:label "Leishmania  major LmSTI1" ;
  rdfs:comment "A LmSTI1 protein that is part of Leishmania  major" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0020241 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0019516 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.0025 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0000104 a rdfs:Class ;
  rdfs:label "TYPHIM VI vaccine" ;
  rdfs:comment "Typhim Vi, Typhoid Vi Polysaccharide Vaccine, for intramuscular use, is a sterile solution containing the cell surface Vi polysaccharide extracted from Salmonella enterica serovar Typhi, S typhi Ty2 strain." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000714 , obo:VO_0003443 , obo:VO_0010451 .

obo:VO_0019709 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003616 , obo:VO_0010427 .

obo:VO_0019913 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluzone Intradermal 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020487 .

obo:VO_0016466 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0005391 a rdfs:Class ;
  rdfs:label "ABO1009-DP vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by Suzhou Abogen Biosciences Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0018393 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe [Pneumorix]" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0016251 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [Hevac B] Box of 1 by Merieux" ;
  rdfs:subClassOf obo:VO_0015917 .

obo:VO_0010214 a rdfs:Class ;
  rdfs:label "Respiratory syncytial virus (RSV), unspecified" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000753 .

obo:VO_0016783 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Diphtherie-Adsorbat-Impfstoff Behring] by Novartis" ;
  rdfs:subClassOf obo:VO_0016724 .

obo:VO_0019918 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Injectable Suspension [Flulaval 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019916 , obo:VO_0020338 .

obo:VO_0019656 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0020320 .

obo:VO_0018730 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0018717 .

obo:VO_0001325 a rdfs:Class ;
  rdfs:label "Brucella abortus subunit vaccine using Bfr" ;
  rdfs:subClassOf obo:VO_0001221 .

obo:VO_0019250 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010425 .

obo:VO_0020546 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Begripal] by Novartis" ;
  rdfs:subClassOf obo:VO_0020543 .

obo:VO_0000420 a rdfs:Class ;
  rdfs:label "pathogen organism component in vaccine" ;
  rdfs:comment "a vaccine component that originates from an organism such as a pathogen or a modified organism." ;
  rdfs:subClassOf obo:VO_0000179 .

obo:VO_0017885 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.005 MG" ;
  rdfs:subClassOf obo:VO_0015070 .

obo:VO_0011498 a rdfs:Class ;
  rdfs:label "Bordetella pertussis FhaB and 69 kDa OMP protein vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0016245 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Fendrix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015913 .

obo:VO_0020625 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0020623 .

obo:VO_0003572 a rdfs:Class ;
  rdfs:label "ProQuad Injectable Product" ;
  rdfs:subClassOf obo:VO_0000091 .

obo:VO_0003211 a rdfs:Class ;
  rdfs:label "human H1N1 influenza monovalent vaccine" ;
  rdfs:comment "A monovalent vaccine used to protect against H1N1 influenza virus." ;
  rdfs:subClassOf obo:VO_0003498 .

obo:VO_0016548 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015984 .

obo:VO_0000589 a rdfs:Class ;
  rdfs:label "Aeromonas vaccine" ;
  rdfs:comment "A bacterial vaccine that is used to protect against Aeromonas bacterial infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0004219 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine encoding MIC8" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:NCBITaxon_12086 a rdfs:Class ;
  rdfs:label "Poliovirus 3" ;
  rdfs:subClassOf obo:NCBITaxon_138950 .

obo:VO_0010979 a rdfs:Class ;
  rdfs:label "NspA from N. meningitidis MC58" ;
  rdfs:comment "Protective antigen [PubMed: 9104804]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:OPL_0000096 a rdfs:Class ;
  rdfs:label "Homo sapiens erythrocyte" ;
  rdfs:comment "An erythrocyte that is a part of or originated from a human (Homo sapiens)." ;
  rdfs:subClassOf obo:CL_0000232 , obo:OPL_0000414 .

obo:VO_0017301 a rdfs:Class ;
  rdfs:label "Bordetella pertussis / diphtheria toxoid vaccine, inactivated / pertactin adsorbed / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 , obo:VO_0017300 , obo:VO_0017801 .

obo:VO_0005276 a rdfs:Class ;
  rdfs:label "LNP-nCOV saRNA-02 vaccine" ;
  rdfs:comment "A SARS-CoV-2 self-amplifying RNA vaccine sponsored by MRC/UVRI and LSHTM Uganda Research Unit" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0016094 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015992 .

obo:VO_0017511 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017507 , obo:VO_0017516 .

obo:VO_0016364 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0003259 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003421 .

obo:VO_0016409 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0007051 a rdfs:Class ;
  rdfs:label "URLC10 peptide vaccine" ;
  rdfs:comment "A cancer vaccine containing URLC10 (up-regulated lung cancer 10) epitopes with potential immunostimulatory and antineoplastic activities. Upon administration, URL peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against URLC10-expressing tumor cells. Up-regulated in lung and esophageal cancers, the function of URLC10 is unknown." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0007436 a rdfs:Class ;
  rdfs:label "multi-glioblastoma-peptide-targeting autologous dendritic cell vaccine ICT-107" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with six synthetic glioblastoma (GBM) peptides: absent in melanoma 2 (AIM-2), melanoma-associated antigen 1 (MAGE-1), tyrosinase-related protein 2 (TRP-2), glycoprotein 100 (gp100), epidermal growth factor receptor 2 (HER-2), interleukin-13 receptor subunit alpha-2 (IL-13Ra2), with potential immunostimulatory and antineoplastic activities. Mononuclear cells obtained via leukapheresis are differentiated into DCs, and pulsed with the GBM-associated peptides. Upon administration, multi-glioblastoma-peptide-targeting autologous DC vaccine ICT-107 exposes the immune system to GBM-associated antigens, which activates a specific cytotoxic T-lymphocyte (CTL) response against GBM cells. This leads to GBM cell lysis. The six peptides are derived from tumor associated antigens (TAA) expressed on GBM cells and cancer stem cells (CSCs). GBM stem-like cells contain a specific range of antigens that are essential for the neoplastic growth and survival of GBM cells" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0004611 a rdfs:Class ;
  rdfs:label "VMCL vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0017878 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.004 MG" ;
  rdfs:subClassOf obo:VO_0015069 .

obo:VO_0018545 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018797 .

obo:VO_0004471 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine pE1D2 encoding E from Dengue Virus 2 strain New Guinea C" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0000333 a rdfs:Class ;
  rdfs:label "Protozoa" ;
  rdfs:comment "Protozoa are a diverse group of unicellular eukaryotic organisms,[1] many of which are motile. Originally, protozoa had been defined as unicellular protists with animal-like behavior, e.g., movement. Protozoa were regarded as the partner group of protists to protophyta, which have plant-like behaviour, e.g., photosynthesis.(http://en.wikipedia.org/wiki/Protozoa)" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:VO_0017061 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017678 .

obo:VO_0001295 a rdfs:Class ;
  rdfs:label "GMDP vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant containing GMDP, a higly effective primary adjuvant." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0002027 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4599.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002381 .

obo:VO_0010391 a rdfs:Class ;
  rdfs:label "Quadracel (inactivated poliovirus component grown in Vero cells) vaccine" ;
  rdfs:subClassOf obo:VO_0010736 .

obo:NCBITaxon_3044472 a rdfs:Class ;
  rdfs:label "Orthoherpesviridae" ;
  rdfs:subClassOf obo:NCBITaxon_548681 .

obo:VO_0018726 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection [Typherix] Box of 10" ;
  rdfs:subClassOf obo:VO_0018725 , obo:VO_0018729 .

obo:VO_0018533 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018528 , obo:VO_0018623 .

obo:VO_0019477 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.02 MG/ML / tetanus toxoid vaccine, inactivated 0.048 MG/ML [OmniHIB]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0003121 , obo:VO_0010436 .

obo:VO_0016262 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 3 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0015922 .

obo:VO_0003102 a rdfs:Class ;
  rdfs:label "Hexavax vaccine" ;
  rdfs:comment "A combination vaccine designed to protect against six different diseases." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000484 , obo:VO_0000561 , obo:VO_0000640 , obo:VO_0000664 , obo:VO_0000712 , obo:VO_0000735 , obo:VO_0000746 , obo:VO_0000765 , obo:VO_0001214 .

obo:VO_0004139 a rdfs:Class ;
  rdfs:label "CVD 915 vaccine" ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0005157 a rdfs:Class ;
  rdfs:label "Moderna COVID-19 vaccine" ;
  rdfs:comment "A SARS-CoV2 RNA vaccine made of lipid nanoparticle with mRNA which encodes the S-2P antigen, made of the SARS-CoV-2 glycoprotein with a transmembrane anchor and intact S1-S2 cleavage site." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0000214 a rdfs:Class ;
  rdfs:label "pCI-neo DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019958 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Fluzone 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019952 , obo:VO_0020481 .

obo:VO_0018809 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003371 .

obo:VO_0005393 a rdfs:Class ;
  rdfs:label "Almansour-001 vaccine" ;
  rdfs:comment "A SARS-CoV-2 DNA vaccine developed by Imam Abdulrahman Bin Faisal University." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0003209 a rdfs:Class ;
  rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0003200 .

obo:VO_0010322 a rdfs:Class ;
  rdfs:label "Bordetella Pertussis Fimbriae Serotype 2 And 3 Antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:CHEBI_17076 a rdfs:Class ;
  rdfs:label "streptomycin" ;
  rdfs:comment "A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class" ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0016222 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Gerke" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:VO_0005467 a rdfs:Class ;
  rdfs:label "tetanus and diphtheria toxoids, adsorbed, preservative free, for adult use, Lf unspecified" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0005197 a rdfs:Class ;
  rdfs:label "SKYCovione vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by SK Bioscience Co., Ltd., and equipped with an aluminum hydroxide adjuvant" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0002427 a rdfs:Class ;
  rdfs:label "Feline Immunodeficiency-Leukemia virus vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000843 , obo:VO_0001465 , obo:VO_0001508 .

obo:VO_0010159 a rdfs:Class ;
  rdfs:label "tetanus and diphtheria toxoids, adsorbed, preservative free, for adult use (5 Lf of tetanus toxoid and 2 Lf of diphtheria toxoid)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0002860 a rdfs:Class ;
  rdfs:label "obsolete Neisseria meningitidis metH/siaD mutant vaccine" ;
  rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" .

obo:VO_0006042 a rdfs:Class ;
  rdfs:label "Pneumococcal conjugate vaccine 20-valent (PCV20) polysaccharide CRM197 conjugate adjuvant preservative free" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010453 .

obo:VO_0019967 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluvirin 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019948 .

obo:VO_0005475 a rdfs:Class ;
  rdfs:label "NanoAlum vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that reformulates Alhydrogel as a stable nanoparticle with the anionic polymer polyacrylic acid (PAA), leading to the induction of structure-dependent TH1 response." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002191 a rdfs:Class ;
  rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.26)" .

obo:VO_0003342 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0005348 a rdfs:Class ;
  rdfs:label "LYB001 vaccine" ;
  rdfs:comment "A COVID-19 virus-like particle vaccine developed by Yantai Patronus Biotech Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005205 .

obo:VO_0020863 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Stada]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020893 .

obo:VO_0001230 a rdfs:Class ;
  rdfs:label "Treponema pallidum vaccine" ;
  rdfs:comment "Vaccine that protects against Treponema pallidum infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003494 .

obo:VO_0000022 a rdfs:Class ;
  rdfs:label "Brucella abortus vaccine strain 19" ;
  rdfs:comment "A live attenuated Brucella abortus vaccine that is licensed and used in many countries." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000643 , obo:VO_0001134 .

obo:VO_0003659 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010309 , obo:VO_0010415 .

obo:VO_0015136 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015135 .

obo:VO_0017696 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax]" ;
  rdfs:subClassOf obo:VO_0017685 , obo:VO_0017747 .

obo:VO_0003542 a rdfs:Class ;
  rdfs:label "Sedoreovirinae vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Sedoreovirinae." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003541 .

obo:VO_0000609 a rdfs:Class ;
  rdfs:label "viral vaccine" ;
  rdfs:comment "A vaccine that targets against a viral disease." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005504 .

obo:VO_0004685 a rdfs:Class ;
  rdfs:label "BoHV-4-A-gD(cp)gD(106)DeltaTK vaccine" ;
  rdfs:subClassOf obo:VO_0001366 .

obo:VO_0002120 a rdfs:Class ;
  rdfs:label "Canine Parainfluenza-Bordetella Bronchiseptica Modified Live Virus, Avirulent Live Culture Vaccine (USDA: 14M1.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002418 , obo:VO_0007748 .

obo:NCBITaxon_83554 a rdfs:Class ;
  rdfs:label "Chlamydia psittaci" ;
  rdfs:subClassOf obo:NCBITaxon_810 .

obo:VO_0020406 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0020387 , obo:VO_0020413 .

obo:VO_0003277 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Product" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000419 , obo:VO_0000455 .

obo:VO_0001390 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine pGFP-TSA1" ;
  rdfs:comment "A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi TSA-1 protein." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0004235 a rdfs:Class ;
  rdfs:label "rHA with IL-1Beta adjuvant vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0019236 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0010257 a rdfs:Class ;
  rdfs:label "vaccine adjuvant variable" ;
  rdfs:comment "A variable representing the vaccine adjuvant (silver) etc." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0020433 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Sanofi" ;
  rdfs:subClassOf obo:VO_0020410 .

obo:VO_0003561 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 9V vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0020705 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] Box of 5" ;
  rdfs:subClassOf obo:VO_0020703 , obo:VO_0020708 .

obo:VO_0015265 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015232 , obo:VO_0015263 .

obo:VO_0019798 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0004214 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine-Erysipelothrix Rhusiopathiae-Haemophilus Parasuis Bacterin (USDA: 49V9.20)" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0001217 , obo:VO_0001456 , obo:VO_0001802 , obo:VO_0003535 .

obo:VO_0004520 a rdfs:Class ;
  rdfs:label "Herpes Simplex Virus Type 1 DNA Vaccine encoding 5gP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0017483 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML [T-Immun Immuno]" ;
  rdfs:subClassOf obo:VO_0017684 .

obo:VO_0001602 a rdfs:Class ;
  rdfs:label "avian influenza H9N2 Subtype, Killed Virus Vaccine (USDA: 1057.H9)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0018361 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003341 .

obo:VO_0004373 a rdfs:Class ;
  rdfs:label "Leishmania major DNA vaccine KMP-11" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001231 .

obo:NCBITaxon_175121 a rdfs:Class ;
  rdfs:label "Passeroidea" ;
  rdfs:subClassOf obo:NCBITaxon_3073809 .

obo:VO_0001777 a rdfs:Class ;
  rdfs:label "equine influenza modified live virus vaccine (USDA: 1501.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0001178 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0007743 a rdfs:Class ;
  rdfs:label "whole tumor cell-based leukemia vaccine" ;
  rdfs:comment "A cancer vaccine administered within the first 2 to 3 months after allogeneic stem cell transplantation may enhance graft-vs.-leukemia responses. Irradiated autologous cancer cells provide a source of tumor antigens at the vaccination site. Granulocyte macrophage colony-stimulating factor (GM-CSF) secreted by irradiated bystander cells stimulates the recruitment, maturation and immunostimulatory activity of dendritic cells (DCs) at the vaccination site. Autologous whole tumor cell-based vaccination may tip the balance between leukemia-specific and alloreactive T cell responses in favor of a graft-vs.-leukemia (GvL) effect." ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0002663 a rdfs:Class ;
  rdfs:label "trxA from Salmonella Typhimurium" ;
  rdfs:comment "A trxA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0011557 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 DNA vaccine pRSV-gC" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000987 .

obo:VO_0020591 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020590 .

obo:VO_0015070 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0003828 a rdfs:Class ;
  rdfs:label "Havrix pediatric/adolescent vaccine 720 UNT in 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003830 .

obo:VO_0018242 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Vaccine 35000 PFU/ML / Rubella virus 1400 PFU/ML / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000737 .

obo:VO_0011245 a rdfs:Class ;
  rdfs:label "TBEVgp1 polyprotein" ;
  rdfs:comment "Series of plasmid constructs encoding different forms of the envelope glycoprotein E of the flavivirus tick-borne encephalitis virus were constructed. These included a secreted recombinant subviral particle, a secreted carboxyl-terminally truncated soluble homodimer, a nonsecreted full-length form, and an inefficiently secreted truncated form. Mice were immunized using both i.m. injection and Gene Gun-mediated application of plasmids. The functional immune response was evaluated by determining specific neutralizing and hemagglutination-inhibiting Ab activities and by challenging the mice with a lethal dose of the virus.The plasmid construct encoding a secreted subviral particle, which carries multiple copies of the protective Ag on its surface, was superior to the other constructs in terms of extent and functionality of the Ab response as well as protection against virus challenge [PubMed: 10586074]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010793 .

obo:VO_0016234 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 50 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015907 .

obo:VO_0003304 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 31 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003299 , obo:VO_0010446 .

obo:VO_0003884 a rdfs:Class ;
  rdfs:label "Flublok 2014-2015 Formula Influenza Virus Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003883 .

obo:VO_0001315 a rdfs:Class ;
  rdfs:label "SPT (Antigen Formulation)" ;
  rdfs:comment "An emulsion vaccine adjuvant that is an emulsion of squalane (5%), Tween 80( 0.2%), Pluronic L121( 1.25%), phosphate-buffered saline pH 7.4, and antigen." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0004081 a rdfs:Class ;
  rdfs:label "V-LSG1 + V-LSG2 vaccine" ;
  rdfs:subClassOf obo:VO_0012177 .

obo:VO_0001462 a rdfs:Class ;
  rdfs:label "fish vaccine" ;
  rdfs:comment "Vaccine that used for immunizing fishes." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001218 .

obo:VO_0007097 a rdfs:Class ;
  rdfs:label "plasmacytoid dendritic cell vaccine" ;
  rdfs:comment "A whole cell vaccine derived from a distinct subset of dendritic cells (DCs) with a plasma cell-like morphology that exhibits immunomodulating activity. Plasmacytoid dendritic cells (pDCs) express a characteristic set of surface markers, such as CD123 (interleukin-3 receptor alpha chain), BDCA-2 (blood dendritic cell antigen 2; CD303) and BDCA-4 (CD304), as well as intracellular toll-like receptors 7 and 9. Upon stimulation, the activated pDCs produce substantial amounts of interferon (IFN) alpha, and to a lesser degree IFN-beta, as well as other cytokines and chemokines, such as tumor necrosis factor alpha and interleukins 1, 6 and 8. In addition, these pDCs, directly or indirectly stimulate T-cells, B-cells and natural killer cells. This may potentially lead to increased immunity against tumor cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0002065 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease Killed Virus Vaccine (USDA: 12G5.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002365 , obo:VO_0007748 .

obo:VO_0019921 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0004145 a rdfs:Class ;
  rdfs:label "shiga toxin 2 B subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0016353 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:VO_0007578 a rdfs:Class ;
  rdfs:label "autologous dendritic cells (DCs) vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0020999 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 PFU Injection" ;
  rdfs:subClassOf obo:VO_0020997 .

obo:VO_0003200 a rdfs:Class ;
  rdfs:label "Bordetella pertussis toxoid vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0003196 .

obo:VO_0005380 a rdfs:Class ;
  rdfs:label "Mastoparan 7 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017896 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0019347 a rdfs:Class ;
  rdfs:label "0.5 ML Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0088 MG/ML / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0010211 , obo:VO_0010445 .

obo:VO_0017687 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Covaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0017686 , obo:VO_0017704 , obo:VO_0017743 .

obo:DOID_7427 a rdfs:Class ;
  rdfs:label "anthrax disease"@en ;
  rdfs:comment "A primary bacterial infectious disease that results_in infection located_in skin, located_in lung lymph nodes or located_in gastrointestinal tract, has_material_basis_in Bacillus anthracis, transmitted_by contact with infected animals or animal products, transmitted_by airborne spores or transmitted_by ingestion of undercooked meat from infected animals and has_symptom skin ulcer, has_symptom nausea, has_symptom poor appetite, has_symptom bloody diarrhea, has_symptom fever or has_symptom shortness of breath."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:VO_0018685 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML" ;
  rdfs:subClassOf obo:VO_0004815 .

obo:NCBITaxon_738 a rdfs:Class ;
  rdfs:label "Glaesserella parasuis" ;
  rdfs:subClassOf obo:NCBITaxon_712 .

obo:VO_0005029 a rdfs:Class ;
  rdfs:label "pCP15/60 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCP15/60." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0021126 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0004200 a rdfs:Class ;
  rdfs:label "Streptococcus agalactiae BipA protein vaccine" ;
  rdfs:subClassOf obo:VO_0001375 .

obo:VO_0004643 a rdfs:Class ;
  rdfs:label "CAdVax-Den12/Den34 vaccine" ;
  rdfs:subClassOf obo:VO_0000725 .

obo:VO_0011396 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum Hsp90 protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000534 .

obo:VO_0004828 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 1150000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0004822 .

obo:VO_0019118 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2020 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020490 .

obo:VO_0001945 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0020073 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.09 MG/ML Prefilled Syringe [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0016815 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0016732 , obo:VO_0016764 .

obo:VO_0005146 a rdfs:Class ;
  rdfs:label "VRC-SRSDNA015-00-VP vaccine" ;
  rdfs:comment "A SARS DNA vaccine made of a single closed plasmid DNA marcromolecule (VRC-8138) that produces a deletion mutant of the SARS Spike glycoprotein" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0012183 .

obo:VO_0007386 a rdfs:Class ;
  rdfs:label "Glioma-Associated Antigen Peptide-Pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of autologous dendritic cells pulsed with synthetic glioma-associated antigen (GAA) peptides with potential antineoplastic activity. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against GAA peptide-expressing glioma cells, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0003363 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010295 , obo:VO_0010444 .

obo:VO_0000633 a rdfs:Class ;
  rdfs:label "Brucella melitensis Rev. 1 with P39 deletion vaccine" ;
  rdfs:comment "A B. melitensis vaccine that is recombinant B. melitensis Rev. 1 vaccine with the p39 gene deletion." ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0001736 a rdfs:Class ;
  rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1952.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001019 , obo:VO_0007748 .

obo:VO_0003709 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2018-2019 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003708 .

obo:VO_0004793 a rdfs:Class ;
  rdfs:label "HVT-LT vaccine" ;
  rdfs:subClassOf obo:VO_0001488 .

obo:VO_0018115 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Vaccine / Rubella virus vaccine / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000737 .

obo:OGG_2000001224 a rdfs:Class ;
  rdfs:label "gene of Proteobacteria" ;
  rdfs:comment "A gene of an organism of Proteobacteria" ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:OPL_0000297 a rdfs:Class ;
  rdfs:label "Plasmodium schizont stage" ;
  rdfs:comment "A schizont stage in the Plasmodium lifecycle that occurs in erythrocytes or in hepatocytes." ;
  rdfs:subClassOf obo:OPL_0000084 .

obo:VO_0005302 a rdfs:Class ;
  rdfs:label "Adjuplex+GLA vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017211 a rdfs:Class ;
  rdfs:label "10 ML tetanus toxoid vaccine, inactivated 8 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003405 .

obo:VO_0000728 a rdfs:Class ;
  rdfs:label "RNA vaccine role" ;
  rdfs:comment "A vaccine role that indicates the vaccine being a RNA vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0007346 a rdfs:Class ;
  rdfs:label "B7.1/​IL-2 leukaemia cell vaccine" ;
  rdfs:comment "A cancer vaccine containing human acute myeloid leukemic (AML) blasts that have been genetically engineered to express a B7.1/IIL-2 fusion protein. It uses B7.1 (CD80)/IL-2 immune gene therapy for high risk MDS RAEB-2 and acute myeloid leukaemia (AML) patients who are unsuitable for an allogeneic haematological stem cell transplant." ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0000402 a rdfs:Class ;
  rdfs:label "AIDSVAX vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0007226 a rdfs:Class ;
  rdfs:label "Allogeneic GM-CSF-secreting Tumor Vaccine PANC 6.03 pcDNA-1/GM-Neo" ;
  rdfs:comment "An allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with a plasmid carrying the gene for cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Allogeneic GM-CSF-secreting tumor vaccine PANC 6.03 pcDNA-1/GM-Neo secretes GM-CSF thereby activating dendritic cells, promoting antigen presentation to B- and T-cells, and promoting a cytotoxic T-lymphocyte (CTL) response. This may eventually kill tumor cells. The pancreatic tumor cells are derived from the PANC 6.03 tumor cell line." ;
  rdfs:subClassOf obo:VO_0005430 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0019645 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML [Fluad 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020309 .

obo:VO_0020468 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typhim VI] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020449 .

obo:VO_0020518 a rdfs:Class ;
  rdfs:label "0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML Nasal Spray [FluMist Quadrivalent] by Astrazeneca" ;
  rdfs:subClassOf obo:VO_0020517 .

obo:VO_0005041 a rdfs:Class ;
  rdfs:label "pCMVi(-H3)Ubs DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCMVi(-H3)Ubs.  This plasmid contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001644 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.16)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0015230 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML Injection [Vivaxim]" ;
  rdfs:subClassOf obo:VO_0015229 , obo:VO_0015340 .

obo:VO_0018234 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Prefilled Syringe [Priorix]" ;
  rdfs:subClassOf obo:VO_0018232 , obo:VO_0018233 .

obo:VO_0002016 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Modified Killed Virus Vaccine (USDA: 1935.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0002374 .

obo:VO_0018076 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0018052 , obo:VO_0018156 .

obo:VO_0003844 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003837 .

obo:VO_0011116 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/chicken/Italy/13474/99(H7N1))" ;
  rdfs:comment "Mice and ferrets were immunised with two doses of the split virus vaccine (12-24 microg haemagglutinin derived from Influenza A virus (A/chicken/Italy/13474/99(H7N1))) with or without aluminium hydroxide adjuvant and challenged 3 weeks after second dose with the highly pathogenic A/chicken/Italy/13474/99 (H7N1) virus.  The vaccine induced significant protection from disease after challenge with the wild-type virus. In the murine lethal challenge model, vaccination effectively prevented death and, furthermore, formulation with adjuvant reduced excessive weight loss and viral shedding [PubMed: 19453487]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0020761 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG Injectable Solution [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020759 , obo:VO_0020760 , obo:VO_0020805 .

obo:VO_0000220 a rdfs:Class ;
  rdfs:label "pCMVI.UBF3/2 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003248 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 3 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0007184 a rdfs:Class ;
  rdfs:label "telomerase: 540-548 peptide vaccine" ;
  rdfs:comment "A recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT). Telomerase expression has been directly linked to tumor development; its catalytic subunit is expressed in the majority of human cancer cells, but infrequently in normal cells. Vaccination with telomerase:540-548 peptide may stimulate cytotoxic T cells to recognize and kill telomerase-expressing cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0004789 a rdfs:Class ;
  rdfs:label "rBCG-SIVgag vaccine" ;
  rdfs:subClassOf obo:VO_0000751 .

obo:VO_0015125 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015122 , obo:VO_0015289 .

obo:VO_0010424 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2020-2021" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0015677 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015562 , obo:VO_0015771 .

obo:VO_0020053 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Injectable Suspension [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020478 .

obo:VO_0004066 a rdfs:Class ;
  rdfs:label "Leishmania infantum SMT protein vaccine" ;
  rdfs:subClassOf obo:VO_0012159 .

obo:VO_0000889 a rdfs:Class ;
  rdfs:label "PleuroStar APP vaccine" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001130 .

obo:DOID_305 a rdfs:Class ;
  rdfs:label "carcinoma"@en ;
  rdfs:comment "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells."@en ;
  rdfs:subClassOf obo:DOID_0050687 .

obo:VO_0015829 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015624 .

obo:VO_0017072 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017067 , obo:VO_0017547 .

obo:VO_0004674 a rdfs:Class ;
  rdfs:label "SL3261-Pseudomonas aeruginosa serogroup O11 O antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000393 .

obo:VO_0018107 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 20000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0018106 , obo:VO_0018241 .

obo:VO_0002715 a rdfs:Class ;
  rdfs:label "7b from Feline infectious peritonitis virus" ;
  rdfs:comment "A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001434 .

obo:VO_0016515 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0020813 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0017053 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] Box of 25" ;
  rdfs:subClassOf obo:VO_0017050 , obo:VO_0017059 , obo:VO_0017524 .

obo:VO_0018595 a rdfs:Class ;
  rdfs:label "Bacillus anthracis Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000455 , obo:VO_0010434 .

obo:VO_0020581 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC] Box of 10 by Mylan" ;
  rdfs:subClassOf obo:VO_0020580 .

obo:VO_0002269 a rdfs:Class ;
  rdfs:label "Encephalomyelitis Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4867.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000541 , obo:VO_0000640 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0007748 .

obo:VO_0019877 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0002410 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira CanicolaGrippotyphosa-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002411 .

obo:VO_0020777 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 CELLS Injectable Suspension [OncoTICE] Box of 1" ;
  rdfs:subClassOf obo:VO_0020776 , obo:VO_0020779 .

obo:VO_0017403 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxin 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017371 .

obo:VO_0017953 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.03 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0017933 .

obo:NCBITaxon_10261 a rdfs:Class ;
  rdfs:label "Fowlpox virus" ;
  rdfs:subClassOf obo:NCBITaxon_10260 .

obo:VO_0005382 a rdfs:Class ;
  rdfs:label "Precision Vaccines Program (PVP)-037 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002972 a rdfs:Class ;
  rdfs:label "Herpes simplex virus 2 ICP0 mutant vaccine" ;
  rdfs:comment "A live-attenuated HSV-2 ICP0 virus provides significant protection against wild-type HSV-2 (MS strain) challenge in mice" ;
  rdfs:subClassOf obo:VO_0012168 .

obo:VO_0003749 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2017-2018 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003746 .

obo:VO_0015680 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax] Box of 25" ;
  rdfs:subClassOf obo:VO_0015563 , obo:VO_0015774 .

obo:VO_0020383 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003856 , obo:VO_0020374 .

obo:VO_0002123 a rdfs:Class ;
  rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002393 , obo:VO_0007748 .

obo:VO_0019863 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluarix Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020319 .

obo:VO_0007040 a rdfs:Class ;
  rdfs:label "recombinant Vaccinia-MUC1-B7 vaccine" ;
  rdfs:comment "An admixture of recombinant vaccinia virus encoding MUC-1 and recombinant vaccinia virus encoding the murine T-cell co-stimulatory molecule B7.1. MUC-1 is a glycosylated mucin that is overexpressed in breast, lung, pancreatic, prostate, stomach, colon, and ovarian carcinomas. Vaccination with MUC-1 in combination with B7.1 may enhance the cytotoxic T cell (CTL) immune response to tumors expressing MUC-1, compared to vaccination with MUC-1 alone." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005430 , obo:VO_0005484 , obo:VO_0005486 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0018038 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0018037 .

obo:VO_0018892 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0019481 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000746 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0020832 .

obo:VO_0001585 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis Killed Virus Vaccine (USDA: 1015.10)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0000712 , obo:VO_0001522 , obo:VO_0007748 .

obo:VO_0019758 a rdfs:Class ;
  rdfs:label "influenza A virus A/Delaware/39/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Nebraska/14/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Injectable Suspension [Flucelvax Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020333 .

obo:VO_0003973 a rdfs:Class ;
  rdfs:label "Pentacel vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003972 .

obo:VO_0010263 a rdfs:Class ;
  rdfs:label "vaccine challenge study design" ;
  rdfs:comment "A vaccine study design that is about the vaccine challenge to a host." ;
  rdfs:subClassOf obo:VO_0010261 .

obo:BFO_0000006 a rdfs:Class ;
  rdfs:label "spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:VO_0018645 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine / L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine / L1 protein, Human papillomavirus type 6 Vaccine Injectable Suspension [Gardasil]" ;
  rdfs:subClassOf obo:VO_0000049 , obo:VO_0018644 .

obo:VO_0000833 a rdfs:Class ;
  rdfs:label "Yersinia PAV vaccine" ;
  rdfs:comment "A Yersinia pestis subunit vaccine that contains staphylococcal protein A-V antigen fusion peptide (PAV). PMID:7622225." ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0015518 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0003230 .

obo:VO_0017143 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0017129 , obo:VO_0017604 .

obo:VO_0015222 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015218 .

obo:VO_0018067 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018066 .

obo:VO_0004804 a rdfs:Class ;
  rdfs:label "BL21(DE3)/pUTa-E + pET28a-FT vaccine" ;
  rdfs:subClassOf obo:VO_0002506 .

obo:VO_0006064 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 50 mcg/0.5 mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0007695 a rdfs:Class ;
  rdfs:label "mRNA tumor antigen DC vaccine" ;
  rdfs:comment "A cancer vaccine made with dendritic cells (DCs) pulsed with mRNA encoded tumor antigens. These personalized cell vaccines may lead to antitumor specific T cell responses. " ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0005428 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0020833 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b 0.035 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020836 .

obo:VO_0017871 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.25 MG/ML" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0015558 a rdfs:Class ;
  rdfs:label "1 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015528 , obo:VO_0015560 .

obo:VO_0003895 a rdfs:Class ;
  rdfs:label "Flublok 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003894 .

obo:VO_0007635 a rdfs:Class ;
  rdfs:label "MAGE-A12:170-178 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0002405 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0001490 , obo:VO_0002393 , obo:VO_0002417 .

obo:VO_0017192 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017189 , obo:VO_0017198 , obo:VO_0017634 .

obo:VO_0015742 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015495 , obo:VO_0015807 .

obo:VO_0015536 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0010490 a rdfs:Class ;
  rdfs:label "licensed human melanoma vaccine" ;
  rdfs:comment "Melanoma vaccine that is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000635 .

obo:VO_0010964 a rdfs:Class ;
  rdfs:label "Iss" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0001304 a rdfs:Class ;
  rdfs:label "Murapalmitine vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant called murapalmitine." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0003917 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML / influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML [FLUAD 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003910 .

obo:VO_0002180 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass & Conn Types Vaccine (USDA: 17B1.17)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0001867 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E8.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0001217 , obo:VO_0002437 , obo:VO_0007748 .

obo:VO_0011369 a rdfs:Class ;
  rdfs:label "cancer DNA vaccine encoding TEM8" ;
  rdfs:comment "An xenogenic DNA vaccine encoding human TEM8 carried by attenuated Salmonella typhimurium to help reduce tumor growth and suppress angiogenesis in the tumors." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0001015 a rdfs:Class ;
  rdfs:label "obsolete viral vaccine organism live attenuated" ;
  rdfs:comment "A live attenuated quality of a virus vaccine strain. " .

obo:VO_0003890 a rdfs:Class ;
  rdfs:label "Flublok 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000978 , obo:VO_0010432 .

obo:VO_0000584 a rdfs:Class ;
  rdfs:label "immune response detection assay" ;
  rdfs:comment "An assay that is used to detect the immune response of a host to vaccination of a vaccine." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0007498 a rdfs:Class ;
  rdfs:label "long peptide vaccine 7" ;
  rdfs:comment "A peptide vaccine consisting of a combination of seven synthetic long peptides (SLPs), which are each about 30 amino acids in size, and derived from cancer-testis antigens (CTA) and melanocytic differentiation proteins (MDP), with potential immunostimulating and antitumor activities. Upon administration, long peptide vaccine 7 may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL) response against tumor cells expressing these peptides. CTA and MDP are overexpressed in a variety of cancer cell types." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0018400 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML" ;
  rdfs:subClassOf obo:VO_0003212 .

obo:VO_0010867 a rdfs:Class ;
  rdfs:label "VP30 from Zaire ebolavirus" ;
  rdfs:comment "VP30 expressed from alphavirus replicons induced a protective immune response in BALB/c mice when challenged with Ebola virus Zaire [PubMed: 11485406]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0011476 a rdfs:Class ;
  rdfs:label "Theileria annulata vaccine by Local veterinary institutes" ;
  rdfs:subClassOf obo:VO_0000909 .

obo:VO_0018555 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018720 .

obo:VO_0003252 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 23F vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0018881 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hawaii/70/2019 (H1N1) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0019817 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003649 .

obo:VO_0000311 a rdfs:Class ;
  rdfs:label "Brucella melitensis lipopolysaccharide vaccine" ;
  rdfs:subClassOf obo:VO_0001223 .

obo:VO_0004102 a rdfs:Class ;
  rdfs:label "recombinant DOBV nucleocapsid protein (rDOBV N) vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012167 .

obo:VO_0006071 a rdfs:Class ;
  rdfs:label "SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (Jiangsu Province Centers for Disease Control and Prevention)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0019993 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML [Fluzone Intradermal 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020487 .

obo:VO_0000126 a rdfs:Class ;
  rdfs:label "live attenuated vaccine organism" ;
  rdfs:comment "a vaccine organism that is live and attenuated" ;
  rdfs:subClassOf obo:VO_0000506 .

obo:RO_0000086 a rdf:Property ;
  rdfs:label "has quality"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000019 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:VO_0019391 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0002038 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis-Fowl Pox-Laryngotracheitis Live Virus, Live Fowl Pox Vector Vaccine (USDA: 10S1.R0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002327 , obo:VO_0007748 .

obo:VO_0001673 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001488 , obo:VO_0007748 .

obo:VO_0015959 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 250" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015733 , obo:VO_0015739 , obo:VO_0016049 .

obo:VO_0019153 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 UNT/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0010062 a rdfs:Class ;
  rdfs:label "Plasmodium vivax CelTOS" ;
  rdfs:comment "A CelTOS protein that is part of Plasmodium vivax|A PvCelTOS protein that is part of Plasmodium vivax" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015473 .

obo:NCBITaxon_8782 a rdfs:Class ;
  rdfs:label "Aves" ;
  rdfs:subClassOf obo:NCBITaxon_32561 .

obo:VO_0002670 a rdfs:Class ;
  rdfs:label "obsolete aroA from Shigella" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" .

obo:VO_0016668 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0016626 .

obo:VO_0002742 a rdfs:Class ;
  rdfs:label "P protein from Rabies virus" ;
  rdfs:comment "A P gene mutant is attenuated in mice and induces significant protection from challenge with wild type Rabies virus" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001443 .

obo:VO_0017867 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.01 MG" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0001995 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:UBERON_0000178 a rdfs:Class ;
  rdfs:label "blood" ;
  rdfs:comment "A fluid that is composed of blood plasma and erythrocytes." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:VO_0019582 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020495 .

obo:VO_0017856 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide 0.5 MG" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010290 , obo:VO_0010444 .

obo:VO_0000909 a rdfs:Class ;
  rdfs:label "Theileria annulata vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:NCBITaxon_12091 a rdfs:Class ;
  rdfs:label "Hepatovirus" ;
  rdfs:subClassOf obo:NCBITaxon_2946633 .

obo:VO_0002821 a rdfs:Class ;
  rdfs:label "obsolete B. melitensis WR201 (16M-delta-purEK)" ;
  rdfs:comment "A purE/purK mutant of B. melitensis 16M was attenuated in mice when given intraperitoneally. Nine weeks after immunization, mice were protected from challenge with wild type B. melitensis" .

obo:VO_0010917 a rdfs:Class ;
  rdfs:label "obsolete Hap from H. influenzae" .

obo:VO_0006024 a rdfs:Class ;
  rdfs:label "influenza virus vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0001278 a rdfs:Class ;
  rdfs:label "cancer vaccine immunization" ;
  rdfs:subClassOf obo:VO_0000494 .

obo:VO_0020291 a rdfs:Class ;
  rdfs:label "Vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML Oral Suspension" ;
  rdfs:subClassOf obo:VO_0020292 .

obo:OBI_0000457 a rdfs:Class ;
  rdfs:label "manufacturing"@en ;
  rdfs:comment "A planned process with the objective to produce a processed material which will have a function for future use."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:VO_0003349 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0003347 .

obo:VO_0000521 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine encoding PA83 and LF" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0003855 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003849 .

obo:VO_0019272 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020345 .

obo:VO_0003930 a rdfs:Class ;
  rdfs:label "Fluad 2018-2019 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003928 .

obo:VO_0005001 a rdfs:Class ;
  rdfs:label "pCAGGS/MCS DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCAGGS/MCS.  This plasmid has a chicken beta-actin promoter, contains a multiple cloning site between the EcoRI and BglII sites of the rabbit beta-globin gene, and has restriction sites for the enzymes SacI, ClaI, NsiI, Asp718, SmaI, SphI, XhoI, and NheI." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0020647 a rdfs:Class ;
  rdfs:label "1 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution [Varilrix]" ;
  rdfs:subClassOf obo:VO_0021014 .

obo:VO_0020343 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2019-2020 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 , obo:VO_0010420 .

obo:VO_0018073 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 50 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018072 .

obo:VO_0005313 a rdfs:Class ;
  rdfs:label "Th17 immune profile" ;
  rdfs:comment "An immune profile that is characterized by the presence of T helper 17 cells (Th17), a subset of pro-inflammatory T helper cells defined by their production of interleukin 17 (IL-17). They are related to T regulatory cells and the signals that cause Th17 to differentiate and inhibit Treg differentiation." ;
  rdfs:subClassOf obo:VO_0005308 .

obo:VO_0019328 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.04 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018802 .

obo:VO_0018515 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 20 by European" ;
  rdfs:subClassOf obo:VO_0018506 .

obo:NCBITaxon_2560319 a rdfs:Class ;
  rdfs:label "avian paramyxovirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_2560069 .

obo:VO_0017983 a rdfs:Class ;
  rdfs:label "0.6 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Menjugate] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017968 .

obo:VO_0020602 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Xanaflu] by Mylan" ;
  rdfs:subClassOf obo:VO_0020599 .

obo:VO_0002938 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica sodA mutant vaccine" ;
  rdfs:comment "A sodA mutant in Yersinia enterocolitica was highly attenuated and mice immunized with a single oral dose of the mutant strain were protected against a lethal oral-challenge infection with wild-type Y. enterocolitica" ;
  rdfs:subClassOf obo:VO_0012186 .

obo:VO_0010811 a rdfs:Class ;
  rdfs:label "Lawsonia intracellularis protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0000413 a rdfs:Class ;
  rdfs:label "recombinant chimera BLSOmp31 vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000709 .

obo:VO_0018346 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG" ;
  rdfs:subClassOf obo:VO_0003337 .

obo:VO_0011348 a rdfs:Class ;
  rdfs:label "5CVMB vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0016167 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0016003 .

obo:VO_0007025 a rdfs:Class ;
  rdfs:label "NY-ESO-1 plasmid DNA cancer vaccine" ;
  rdfs:comment "A plasmid DNA encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1 with potential immunostimulating and antitumor activities. Upon administration, NY-ESO-1 plasmid DNA cancer vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the NY-ESO-1 antigen, resulting in tumor cell lysis. NY-ESO-1 is a tumor associated antigen (TAA) found in normal testes and expressed on the surfaces of various tumor cells, including melanoma, breast, bladder, prostate, lung, ovarian, and hepatocellular tumor cells." ;
  rdfs:subClassOf obo:VO_0003140 , obo:VO_0005425 , obo:VO_0005485 , obo:VO_0005495 , obo:VO_0005496 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0000418 a rdfs:Class ;
  rdfs:label "Menactra injection 0.5mL vial" ;
  rdfs:comment "Trade Name: Menactra" ;
  rdfs:subClassOf obo:VO_0000071 .

obo:VO_0007480 a rdfs:Class ;
  rdfs:label "cancer stem cell-loaded dc vaccine" ;
  rdfs:comment "A cancer vaccine made of peripheral blood and tumor specimen harvested from patients with metastatic adenocarcinoma of the pancreas to generate cancer stem cell (CSC)-loaded denritic cell (DC) vaccines. CSC-primed antibodies and T cells are capable of selective targeting CSCs and conferring antitumor immunity." ;
  rdfs:subClassOf obo:VO_0005430 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0010177 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, H5N1, A/Vietnam/1203/2004 (national stockpile)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0007237 a rdfs:Class ;
  rdfs:label "Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with four alpha-fetoprotein (AFP) peptides, with potential immunostimulatory and antineoplastic activities. Upon administration, AFP peptide-pulsed autologous dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against AFP-expressing cancer cells, resulting in tumor cell lysis. AFP is overexpressed in a variety of cancer cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005429 , obo:VO_0007657 .

obo:VO_0020524 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020851 .

obo:VO_0018192 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus vaccine Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018191 .

obo:VO_0020499 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:OPL_0000281 a rdfs:Class ;
  rdfs:label "Plasmodium trophozoite" ;
  rdfs:comment "A Plasmodium that is a feeding form which has a single nucleus during the trophozoite stage. Depending on its location, it is either called hepatic or erythrocytic trophozoite." ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:IAO_8000000 a rdfs:Class ;
  rdfs:label "ontology module"@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:VO_0004608 a rdfs:Class ;
  rdfs:label "Bordetella pertussis BPZE vectored vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0001864 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Killed Chlamydia Vaccine (USDA: 16E6.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0002437 , obo:VO_0007748 .

obo:VO_0005378 a rdfs:Class ;
  rdfs:label "NLRP3 receptor role" ;
  rdfs:comment "A role of a material entity that binds to NLRP3." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0003513 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0003497 .

obo:VO_0017306 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 LFU/ML / Pertussis Vaccine 0.0468 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017302 .

obo:VO_0015158 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0003401 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0004807 a rdfs:Class ;
  rdfs:label "Bacillus Calmette-Guérin Danish vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001519 , obo:VO_0010443 .

obo:VO_0017016 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 20 by Novartis" ;
  rdfs:subClassOf obo:VO_0017014 .

obo:VO_0003055 a rdfs:Class ;
  rdfs:label "Infectious pancreatic necrosis virus vaccine" ;
  rdfs:comment "A viral vaccine against infection of an infectious pancreatic necrosis virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0019530 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.04 MG/ML [Recombivax]" ;
  rdfs:subClassOf obo:VO_0003230 .

obo:VO_0020439 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 10000000000 UNT Delayed Release Oral Capsule [Vivotif] by Paxvax Berna" ;
  rdfs:subClassOf obo:VO_0020390 .

obo:VO_0015994 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0015659 , obo:VO_0015779 .

obo:VO_0005330 a rdfs:Class ;
  rdfs:label "CPDI-01 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017132 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [T Wellcovax] Box of 1 by Ribosepharm" ;
  rdfs:subClassOf obo:VO_0017131 .

obo:BFO_0000182 a rdfs:Class ;
  rdfs:label "history"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:DOID_8659 a rdfs:Class ;
  rdfs:label "chickenpox"@en ;
  rdfs:comment "A viral infectious disease that results_in infection located_in skin, has_material_basis_in Human herpesvirus 3, which is transmitted_by direct contact with secretions from the rash, or transmitted_by droplet spread of respiratory secretions. The infection has_symptom anorexia, has_symptom myalgia, has_symptom nausea, has_symptom fever, has_symptom headache, has_symptom sore throat, and has_symptom blisters."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0002564 a rdfs:Class ;
  rdfs:label "manB from B. melitensis" ;
  rdfs:comment "Mutants manB and manA were attenuated in Brucella melitensis and provided protection against challenge in mice's livers" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001400 .

obo:VO_0019789 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML Prefilled Syringe [Afluria 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003727 , obo:VO_0019788 .

obo:VO_0010300 a rdfs:Class ;
  rdfs:label "influenza B virus B/Utah/9/2014 antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003519 , obo:VO_0010301 .

obo:VO_0001833 a rdfs:Class ;
  rdfs:label "Mink Distemper-Enteritis Modified Live & Killed Virus Vaccine-Clostridium Botulinum Type C Bacterin-Toxoid (USDA: 4929.31)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0002449 , obo:VO_0007748 , obo:VO_0010475 .

obo:VO_0018876 a rdfs:Class ;
  rdfs:label "influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0019407 a rdfs:Class ;
  rdfs:label "Bacillus anthracis strain V770-NP1-R antigens 0.1 MG/ML [Biothrax]" ;
  rdfs:subClassOf obo:VO_0000014 , obo:VO_0019406 .

obo:VO_0001358 a rdfs:Class ;
  rdfs:label "tensoactive compound vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that includes tensioactive material. Tensioactive materials, surfactants or active surface agents are chemical substances with a polar-non polar structure. These substances have a tendency to locate themselves at the surface creating an adsorbed monomolecular layer on the interface." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017181 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetasorbat] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017180 .

obo:VO_0001829 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.24)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0002477 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0007458 a rdfs:Class ;
  rdfs:label "Human Myeloid Progenitor Cells CLT-008 vaccine" ;
  rdfs:comment "Early-to late-stage myeloid progenitor cells derived from adult human stem cells with potential hematopoietic activity. Upon infusion, human myeloid progenitor cells CLT-008 proliferate into mature myeloid cells, including granulocytes, macrophages, platelets, and erythrocytes. These myeloid progenitor cells die within forty-five days after a burst of hematopoiesis. This agent cannot create lymphoid cells, including T cells associated with graft-versus-host disease" ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0018560 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0018555 , obo:VO_0018723 .

obo:VO_0002845 a rdfs:Class ;
  rdfs:label "Francisella tularensis guaA mutant vaccine" ;
  rdfs:comment "A guaA mutant is highly attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0003962 a rdfs:Class ;
  rdfs:label "Vaxchora Oral Suspension" ;
  rdfs:subClassOf obo:VO_0003957 , obo:VO_0020292 .

obo:VO_0019578 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020491 .

obo:VO_0018748 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Injection [Typherix]" ;
  rdfs:subClassOf obo:VO_0010744 , obo:VO_0018747 .

obo:VO_0015601 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 3" ;
  rdfs:subClassOf obo:VO_0015555 .

obo:VO_0018870 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML [Vaqta]" ;
  rdfs:subClassOf obo:VO_0010745 , obo:VO_0018869 .

obo:OBI_0000047 a rdfs:Class ;
  rdfs:label "processed material"@en ;
  rdfs:comment "Is a material entity that is created or changed during material processing."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0017335 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000742 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0010415 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0017808 .

obo:VO_0001071 a rdfs:Class ;
  rdfs:label "AquaVac Vibrio vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000645 , obo:VO_0000823 .

obo:VO_0019932 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0018375 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003333 .

obo:CHEBI_16199 a rdfs:Class ;
  rdfs:label "urea" ;
  rdfs:comment "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O)." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0011036 a rdfs:Class ;
  rdfs:label "BrkA" ;
  rdfs:comment "A soluble fraction obtained from Bordetella pertussis was evaluated as adjuvant for the pertussis component of the Diphtheria-Pertussis-Tetanus (DPT) vaccine. High levels of antibodies were induced, and a 78% protection rate of mice challenged with live B. pertussis was observed. Two proteins were identified as the 73 kDa N-terminal alpha-domain of BrkA autotransporter protein and the Cpn60/60 kDa chaperonin. Both stimulated antibodies against pertussis and induced a 42% protection rate against the challenge [PubMed: 17011680]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:VO_0010930 a rdfs:Class ;
  rdfs:label "P1 from Coxiella burnetii" ;
  rdfs:comment "The purified recombinant proteins, P1, HspB, and P1-HspB, and whole-cell antigen (WCA) of C. burnetii were used to immunize BALB/c mice.  Protective immunity against Q fever was induced with a recombinant P1 antigen fused with HspB after Coxiella burnetii challenge [PubMed: 16481504 ]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010773 .

obo:VO_0011255 a rdfs:Class ;
  rdfs:label "VP4 from Murine rotavirus" ;
  rdfs:comment "Plasmid DNA vaccines encoding for murine rotaviral proteins VP4, VP6, and VP7 were tested in adult BALB/c mice for their ability to induce immune responses and provide protection against rotavirus challenge.  Vaccines  encoding VP4 were effective in protecting mice against infection after rotavirus (100 ID50) challenge [PubMed: 9015117]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010789 .

obo:VO_0000306 a rdfs:Class ;
  rdfs:label "pRSV0 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016714 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac]" ;
  rdfs:subClassOf obo:VO_0016677 , obo:VO_0016690 , obo:VO_0016720 .

obo:VO_0007523 a rdfs:Class ;
  rdfs:label "melanoma Theraccine vaccine" ;
  rdfs:comment "A synthetic allogeneic cancer vaccine. Melanoma theraccine typically consists of lysed melanoma cells obtained from several melanoma cell lines combined with an adjuvant (such as DETOX or RIBI). This agent may be combined with immunomodulatory cytokines such as interferon alpha. Melanoma theraccine may induce a rise in the level of cytotoxic T-lymphocyte precursors." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0006053 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine D614 prefusion spike recombinant protein subunit (CoV2 preS dTM) AS03 adjuvant added preservative free 5mcg/0.5mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005267 , obo:VO_0005269 .

obo:VO_0018672 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000" ;
  rdfs:subClassOf obo:VO_0004815 .

obo:VO_0015525 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0020632 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0020615 , obo:VO_0021039 .

obo:VO_0003394 a rdfs:Class ;
  rdfs:label "QIV Quebec vaccine" ;
  rdfs:comment "An inactivated quadrivalent influenza vaccine against 2 influenza A strains and 2 influenza B strains for infants 6 months up to 23 months, and if needed it can be administered to children 2 to 17 years old with compromised immune systems and those considered vulnerable and high risk." ;
  rdfs:subClassOf obo:VO_0001176 , obo:VO_0003495 .

obo:VO_0010856 a rdfs:Class ;
  rdfs:label "SodC from B. abortus strain 2308" ;
  rdfs:comment """IMMUNOGENICITY: Induces antigen-specific Th1 immune response, as indicated by the specific induction of serum IgG2a, but not IgG1, antibodies and by the secretion of IFN-alpha but not IL-4, by the Cu/Zn SOD-stimulated splenocytes. Has been used for vaccine development [PubMed: 10816475][PubMed: 11953393][PubMed: 12933826].    

MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replacement exhibited much greater susceptibility to killing by exogenous O(2)(-) than the parental 2308 strain, supporting a role for SodC in protecting this bacterium from O(2)(-) stress. The B abortus sodC mutant was much more sensitive to killing by cultured resident peritoneal macrophages from C57BL6J mice than 2308, and its attenuation in cultured murine macrophages was enhanced when these phagocytes were treated with gamma interferon. The attenuation of the B abortus sodC mutant in both resting and IFN-gamma-activated macrophages was alleviated in the presence of the NADPH oxidase inhibitor apocynin. Consistently, the B abortus sodC mutant also displayed significant attenuation in infected C57BL6J mice compared to the parental strain. These findings suggest that SodC protects B abortus 2308 from the respiratory burst of host macrophages [PubMed: 15845493].""" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0015120 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015111 .

obo:VO_0019367 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.0025 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019518 .

obo:VO_0017425 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 50 LFU/ML / Pertussis Vaccine 24 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 160 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017341 .

obo:VO_0015735 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015800 .

obo:VO_0001190 a rdfs:Class ;
  rdfs:label "vaccine adjuvant usage datum" ;
  rdfs:comment "A measurement datum that indicates the usage of a vaccine adjuvant. Different digital numbers can be used to represent different adjuvants. " ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0005057 a rdfs:Class ;
  rdfs:label "pcDNA3.1/Hygro(-) DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1/Hygro(-).  This plasmid is 5596 base pairs in length and contains a CMV promoter and an ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016594 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0016560 .

obo:VO_0003449 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Oral Product" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000487 .

obo:VO_0003608 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.03 MG/ML / influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluzone Quadrivalent 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003579 .

obo:VO_0019624 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [FluLaval Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003763 , obo:VO_0010427 , obo:VO_0019601 .

obo:VO_0021039 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0021034 .

obo:NCBITaxon_5821 a rdfs:Class ;
  rdfs:label "Plasmodium berghei" ;
  rdfs:subClassOf obo:NCBITaxon_418101 .

obo:VO_0016133 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 50 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015884 .

obo:VO_0011202 a rdfs:Class ;
  rdfs:label "NcDG1" ;
  rdfs:comment "Separate groups of gerbils were immunized with purified recombinant proteins singly or in combinations and animals were then challenged with N. caninum.  The protective efficacy of each vaccination was determined by assessing animal survival rate.  The highest protection efficacy was observed for combined vaccination with NcSRS2 and NcDG1 (67.5% survival) compared to control (17.4% survival).  Vaccination with NcDG1 alone elicited 62.5% survival in the challenge model [PubMed: 15793355]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0003044 a rdfs:Class ;
  rdfs:label "Lymphocytic choriomeningitis virus vaccine" ;
  rdfs:comment "A viral vaccine against infection of a Lymphocytic choriomeningitis virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0019221 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluad Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020313 .

obo:VO_0020080 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.12 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.12 MG/ML Prefilled Syringe [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020478 .

obo:VO_0020039 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain Nasal Spray [FluMist 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020038 , obo:VO_0020347 .

obo:VO_0007684 a rdfs:Class ;
  rdfs:label "KLH-pulsed autologous dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine made with autologous dendritic cells  pulsed with KLH for this vaccination, combined with radiation or a gene therapy agent, TNFerade. TNFerade or radiation serves to generate cell death stimulating the immune response. The dendritic cell vaccine may direct a distant and lasting effective anti-tumor immune response to achieve a local and systemic clinical benefit." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0000235 a rdfs:Class ;
  rdfs:label "life-threatening reaction to previous influenza vaccination" ;
  rdfs:subClassOf obo:VO_0000233 .

obo:VO_0005249 a rdfs:Class ;
  rdfs:label "EXG-5003 vaccine" ;
  rdfs:comment "A SARS-COV-2 temperature-sensitive self-replicating RNA vaccine expressing the receptor binding domain of the SARS-CoV-2 spike protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0004353 a rdfs:Class ;
  rdfs:label "Duck hepatitis B DNA vaccine pcDNA I-S encoding small S proteins" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000644 , obo:VO_0001469 .

obo:VO_0002687 a rdfs:Class ;
  rdfs:label "ompR from Yersinia enterocolitica" ;
  rdfs:comment "A ompR mutant in Yersinia enterocolitica was attenuated and provided a partial protection from challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001425 .

obo:VO_0000532 a rdfs:Class ;
  rdfs:label "subcutaneous route" ;
  rdfs:comment "A route of administration that is loacted in the hypodermis (subcutaneous tissue) region. " ;
  rdfs:subClassOf obo:VO_0000574 .

obo:NCBITaxon_2732461 a rdfs:Class ;
  rdfs:label "Alsuviricetes" ;
  rdfs:subClassOf obo:NCBITaxon_2732406 .

obo:VO_0011123 a rdfs:Class ;
  rdfs:label "NA from Influenza A virus (A/Aichi/2/1968(H3N2))" ;
  rdfs:comment "The protective effect of neuraminidase (NA) was studied in a mouse protection test using isolated neuraminidase of A2/Aichi/68(H3N2) virus and the complete recombinant virus A/eq(Heq-1)-HK(N2) as antigens. Immunized mice were protected against A2/Aichi(H3N2) challenge virus; however, the protection rate was low in comparison to animals immunized with comparable amounts of the complete A2/68(H3N2) virus9 [PubMed: 1126575]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0004049 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus FnbA protein vaccine" ;
  rdfs:subClassOf obo:VO_0002502 .

obo:VO_0011465 a rdfs:Class ;
  rdfs:label "Ebola virus DNA vaccine encoding ZEBOV GP and SEBOV GP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000726 .

obo:VO_0007413 a rdfs:Class ;
  rdfs:label "monoclonal antibody 11D10 anti-idiotype vaccine" ;
  rdfs:comment "A vaccine consisting of a monoclonal antibody (MoAb) directed against an idiotype that mimics a human milk fat globule (HMFG) membrane epitope. Vaccination with monoclonal antibody 11D10 anti-idiotype vaccine induces anti-anti-idiotype antibodies (Ab3) that may react with breast cancer cell lines expressing the HMFG membrane epitope." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0001538 a rdfs:Class ;
  rdfs:label "Mink Distemper Modified Live Virus Vaccine (USDA: 1451.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0007748 , obo:VO_0010475 , obo:VO_0012178 .

obo:VO_0004472 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine pcTPANS1 encoding NS1 fused to the tissue plasminogen activator signal sequence" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0012355 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:VO_0018534 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0018624 .

obo:VO_0001412 a rdfs:Class ;
  rdfs:label "Edwardsiella ictaluri gene" ;
  rdfs:comment "A bacterial gene that is from Edwardsiella ictaluri." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0020011 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 158000000 UNT/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 158000000 UNT/ML [Flumist 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020349 .

obo:UBERON_0001359 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid" ;
  rdfs:comment "A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:VO_0003301 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003299 , obo:VO_0010446 .

obo:VO_0007010 a rdfs:Class ;
  rdfs:label "Personalized Synthetic Long Peptide Breast Cancer Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of one or more long, synthetic peptides derived from patient-specific breast cancer tumor-associated antigens (TAAs), with potential immunomodulating and antineoplastic activities. Upon intramuscular administration of the personalized synthetic long peptide breast cancer vaccine, the peptides stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the TAAs, which results in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0003004 a rdfs:Class ;
  rdfs:label "obsolete Western equine encephalomyelitis virus PE2/E2 mutant virus" ;
  rdfs:comment "A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur" .

obo:VO_0016237 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 50 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015907 .

obo:VO_0018741 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 8 X Oral Tablet Box of 1" ;
  rdfs:subClassOf obo:VO_0018740 .

obo:VO_0003095 a rdfs:Class ;
  rdfs:label "Revaxis vaccine" ;
  rdfs:comment "Revaxis is a Diphtheria, Tetanus and Poliomyelitis (inactivated) vaccine manufactured by Sanofi Pasteur. This vaccine helps boost protection against diphtheria, tetanus and poliomyelitis (polio)." ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000943 , obo:VO_0001214 .

obo:VO_0011180 a rdfs:Class ;
  rdfs:label "P1 from Neisseria meningitidis" ;
  rdfs:comment "Seventeen monoclonal antibodies to one of three main cell surface antigens of Neisseria meningitidis group B were tested for protective efficacy in the infant rat using as challenge seven strains of different class 2/3 protein serotypes.  Survival of the animals was regularly obtained with antibodies to the P1 protein and to LPS [PubMed: 2510417]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0003969 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML" ;
  rdfs:subClassOf obo:VO_0015014 .

obo:VO_0004055 a rdfs:Class ;
  rdfs:label "Streptococcus pyogenes FBP54 protein vaccine" ;
  rdfs:subClassOf obo:VO_0002852 .

obo:VO_0003906 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2018-2019 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003904 .

obo:VO_0020104 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML Prefilled Syringe [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0018618 , obo:VO_0020103 .

obo:VO_0002236 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46L9.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002404 , obo:VO_0007748 .

obo:VO_0004533 a rdfs:Class ;
  rdfs:label "IBDV DNA vaccine pCAGoptiVP2/rVP2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001497 .

obo:VO_0004992 a rdfs:Class ;
  rdfs:label "CoVLP vaccine" ;
  rdfs:comment "A recombinant coronavirus-like particle SARS-CoV-2 vaccine developed by Medicago" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005418 .

obo:DOID_3068 a rdfs:Class ;
  rdfs:label "glioblastoma"@en ;
  rdfs:comment "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes."@en ;
  rdfs:subClassOf obo:DOID_3069 .

obo:VO_0004482 a rdfs:Class ;
  rdfs:label "Vaccinia virus DNA vaccine A33R from strain IHD-J" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000651 .

obo:VO_0018783 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 LFU/ML / Pertussis Vaccine 0.0468 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0019759 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML [Fluarix Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0020321 .

obo:VO_0017179 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetasorbat]" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017624 .

obo:VO_0018772 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0007043 a rdfs:Class ;
  rdfs:label "survivin/p53/HER2 antigen-loaded autologous dendritic cell vaccine" ;
  rdfs:comment "An autologous dendritic cell (DC) vaccine loaded with tumor-associated antigens (TAAs) derived from survivin, p53 and human epidermal growth factor receptor 2 (HER2 or ERBB2), with immunostimulating and antineoplastic activities. Upon administration, this DC vaccine may elicit a potent cytotoxic T-cell (CTL) response against tumor cells expressing these TAAs, resulting in tumor cell death. Survivin, p53 and HER2 are essential in neoplastic growth, and are considered to be universal tumor antigens." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000534 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0005478 a rdfs:Class ;
  rdfs:label "PFS25/28 in Matrix M vaccine" ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000455 , obo:VO_0000534 , obo:VO_0005502 .

obo:VO_0005561 a rdf:Property ;
  rdfs:label "blocks transmission of pathogen via vaccine" ;
  rdfs:comment "A relation between a vaccine and a parasite where the vaccine immunizes against some parasite such that the parasite is blocked transmitting to additional hosts or vectors." ;
  rdfs:domain obo:VO_0000001 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:VO_0005481 , obo:VO_0003355 .

obo:VO_0005562 a rdf:Property ;
  rdfs:label "vaccine immunity response transferrable to organism" ;
  rdfs:comment "A relation between a vaccine X and organism Y where the vaccine X generates an immune response in a vaccinated organism and the immune product (e.g., antibody) can be transferred to the organism Y" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0020488 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016 Southern Hemisphere vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010422 .

obo:NCBITaxon_568815 a rdfs:Class ;
  rdfs:label "Brucella microti CCM 4915" ;
  rdfs:subClassOf obo:NCBITaxon_444163 .

obo:VO_0015686 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 20" ;
  rdfs:subClassOf obo:VO_0015565 , obo:VO_0015779 .

obo:NCBITaxon_38574 a rdfs:Class ;
  rdfs:label "Leishmania donovani species complex" ;
  rdfs:subClassOf obo:NCBITaxon_38568 .

obo:DOID_2394 a rdfs:Class ;
  rdfs:label "ovarian cancer"@en ;
  rdfs:comment "A female reproductive organ cancer that is located_in the ovary."@en ;
  rdfs:subClassOf obo:DOID_1100 , obo:DOID_120 .

obo:VO_0004761 a rdfs:Class ;
  rdfs:label "rMVTT- HPV16-E6/E7 vaccine" ;
  rdfs:subClassOf obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0003084 a rdfs:Class ;
  rdfs:label "influenza A (H1N1) 2009 monovalent vaccine (GlaxoSmithKline)" ;
  rdfs:comment "Product Name: Influenza A (H1N1) 2009 Monovalent Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003211 , obo:VO_0010415 .

obo:VO_0011025 a rdfs:Class ;
  rdfs:label "AsaP1" ;
  rdfs:comment "Passive immunisation of Atlantic salmon with rainbow trout or rabbit anti-AsaP1 antisera conferred significant protection against challenge with a virulent A. salmonicida [Ref1011:Gudmundsdottir et al., 1997]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010814 .

obo:VO_0003468 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated Injectable Product" ;
  rdfs:subClassOf obo:VO_0003464 .

obo:VO_0018135 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML" ;
  rdfs:subClassOf obo:VO_0015052 .

obo:VO_0017312 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / pertactin adsorbed 0.005 MG/ML / Pertussis Vaccine 0.016 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017300 .

obo:VO_0003620 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2015-2016 Injection" ;
  rdfs:subClassOf obo:VO_0003617 .

obo:VO_0006013 a rdfs:Class ;
  rdfs:label "Hepatitis B vaccine (recombinant) 3-antigen Al(OH)3 adjuvanted" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0010439 .

obo:VO_0020063 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluarix 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020315 .

obo:VO_0018917 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:OPL_0000185 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Trypanosoma cruzi." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0020022 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injectable Suspension [FluLaval 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020019 , obo:VO_0020336 .

obo:VO_0005359 a rdfs:Class ;
  rdfs:label "AS02A vaccine adjuvant" ;
  rdfs:comment "An AS02 vaccine adjuvant contains 50 ug MPL and 50ug QS21, 250uL of SB62 (oil/water emulsion) in phosphate buffered saline (PBS) per volume of 0.5 mL." ;
  rdfs:subClassOf obo:VO_0001264 .

obo:VO_0000115 a rdfs:Class ;
  rdfs:label "vaccine-induced T cell activation" ;
  rdfs:subClassOf obo:VO_0000008 .

obo:VO_0016563 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0016558 .

obo:VO_0019567 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluvirin 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003675 , obo:VO_0010427 , obo:VO_0019544 .

obo:VO_0018544 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection Box of 20" ;
  rdfs:subClassOf obo:VO_0018539 .

obo:VO_0016349 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015940 .

obo:VO_0004246 a rdfs:Class ;
  rdfs:label "Anthrax vaccine adsorbed with Squalene adjuvant" ;
  rdfs:subClassOf obo:VO_0010148 .

obo:VO_0016869 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016809 .

obo:PATO_0001018 a rdfs:Class ;
  rdfs:label "physical quality" ;
  rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:VO_0011207 a rdfs:Class ;
  rdfs:label "PiaA" ;
  rdfs:comment "Mice immunized with recombinant PiaA were protected against systemic challenge to a degree similar to those immunized with an existing protein vaccine candidate, PdB (a genetically modified pneumolysin toxoid). Immunization with a combination of both PiuA and PiaA resulted in additive protection and was highly protective against systemic infection with S. pneumoniae [PubMed: 11598041]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0019142 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020478 .

obo:VO_0016844 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 20 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016816 .

obo:VO_0019978 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0003648 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine 0.1 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003645 .

obo:VO_0020050 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Fluvirin 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020471 .

obo:VO_0019232 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2022 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020494 .

obo:VO_0011148 a rdfs:Class ;
  rdfs:label "NS3" ;
  rdfs:comment "Researchers constructed plasmid DNAs encoding JE virus proteins.  Cytotoxic T lymphocytes (CTLs) were induced by NS3 in a mouse model.  Three immunizations with pUJENS3 provided a 50% partial protection from a lethal dose of JE virus [PubMed: 12922097]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010783 .

obo:VO_0018509 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe Box of 20" ;
  rdfs:subClassOf obo:VO_0018503 .

obo:VO_0002556 a rdfs:Class ;
  rdfs:label "trpE from Bordetella bronchiseptica" ;
  rdfs:comment "A trpE mutant, in combination with an aroA mutation, is attenuated in mice and induces significant protection from challenge with wild type B. bronchiseptica" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001407 .

obo:VO_0016523 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0020921 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Live Attenuated, A-California-7-2009 (H1N1) strain Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001178 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0004364 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis DNA vaccine DNAAg85A encoding a single immunogenic M.tb Ag" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:NCBITaxon_1765 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis variant bovis" ;
  rdfs:subClassOf obo:NCBITaxon_1773 .

obo:VO_0003370 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant NADA fusion protein antigen" ;
  rdfs:subClassOf obo:VO_0003960 .

obo:VO_0018791 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 .

obo:VO_0016746 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Revaxis] Box of 20" ;
  rdfs:subClassOf obo:VO_0016711 , obo:VO_0016770 .

obo:VO_0016821 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0016733 , obo:VO_0016770 .

obo:VO_0016198 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015902 .

obo:VO_0018386 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Injectable Solution [Pneumovax 23]" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:VO_0001241 a rdfs:Class ;
  rdfs:label "Alhydrogel vaccine adjuvant" ;
  rdfs:comment "An aluminum hydroxide vaccine adjuvant that is a gel that is made by precipitation of aluminum hydroxide Al(OH)3 under alkaline conditions." ;
  rdfs:subClassOf obo:VO_0000127 .

obo:VO_0015089 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015088 , obo:VO_0015093 , obo:VO_0015247 .

obo:IDO_0000418 a rdfs:Class ;
  rdfs:label "infectious agent vector role"@en ;
  rdfs:comment "An infectious agent transporter role that is borne by an organism active in the transfer of an infectious agent to an organism of another Species and in which the agent is infectious."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0000835 a rdfs:Class ;
  rdfs:label "manufacturer" ;
  rdfs:comment "A person or organization that has a manufacturer role."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0016620 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Twinrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0016600 , obo:VO_0016608 , obo:VO_0016627 .

obo:VO_0018732 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 2000000000 ORGANISMS" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010451 .

obo:VO_0004276 a rdfs:Class ;
  rdfs:label "MDA-modified human apo B-100 peptide vaccine" ;
  rdfs:subClassOf obo:VO_0002793 .

obo:VO_0010047 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum Pf ribosomal protein P0" ;
  rdfs:comment "A Pf ribosomal protein P0 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0002416 a rdfs:Class ;
  rdfs:label "Canine Distemper-Measles vaccine" ;
  rdfs:subClassOf obo:VO_0000654 , obo:VO_0001471 , obo:VO_0012178 .

obo:VO_0018480 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0018457 .

obo:VO_0005410 a rdfs:Class ;
  rdfs:label "SYS6006 vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine by CSPC ZhongQi Pharmaceutical Technology Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0011195 a rdfs:Class ;
  rdfs:label "NcSRS2" ;
  rdfs:comment "NcSAG1 and NcSRS2, the two major immunodominant tachyzoite surface antigens of the apicomplexan parasite Neospora caninum, were investigated for their potential as vaccine candidates in mice.  Results suggest that a combined DNA/recombinant antigen-vaccine, based on NcSAG1 and NcSRS2, respectively, exhibited a highly significant protective effect against experimentally induced cerebral neosporosis in mice [PubMed: 12741509]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0017682 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0017027 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension [T-Immun Immuno] Box of 10" ;
  rdfs:subClassOf obo:VO_0017026 , obo:VO_0017030 , obo:VO_0017504 .

obo:VO_0003417 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003416 .

obo:VO_0000275 a rdfs:Class ;
  rdfs:label "pJW24 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003416 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003415 .

obo:VO_0001687 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1641.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0020981 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, Inactivated, Strain B / Phuket / 3073/2013 & ndash; Analogue strain B / Utah / 9/2014, Wild Type 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0020980 .

obo:VO_0001934 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4439.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002355 .

obo:VO_0019492 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML Injection [ActHIB]" ;
  rdfs:subClassOf obo:VO_0000004 , obo:VO_0019491 .

obo:DOID_48 a rdfs:Class ;
  rdfs:label "male reproductive system disease"@en ;
  rdfs:comment "A reproductive system disease that affects male reproductive organs."@en ;
  rdfs:subClassOf obo:DOID_15 .

obo:VO_0004756 a rdfs:Class ;
  rdfs:label "HVT-ILT(FC-126 strain) vaccine" ;
  rdfs:subClassOf obo:VO_0001488 .

obo:VO_0007397 a rdfs:Class ;
  rdfs:label "hTERT/Survivin/CMV Multipeptide Vaccine" ;
  rdfs:comment "Gene name: CSH1" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0020308 a rdfs:Class ;
  rdfs:label "Agriflu 2012-2013 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0001126 , obo:VO_0010418 .

obo:VO_0016542 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015984 .

obo:OPL_0000336 a rdfs:Class ;
  rdfs:label "Sarcocystis neurona merozoite" ;
  rdfs:comment "A Sarcocystis neurona that is found in the bloodstream of the human host and invades erythrocytes." ;
  rdfs:subClassOf obo:NCBITaxon_42890 .

obo:VO_0005046 a rdfs:Class ;
  rdfs:label "pSecTag2A DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pSecTag2A.  This plasmid is 5159 base pairs in length and contains a CMV promoter and ampicillin reisistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002315 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus Modified Live Virus Vaccine-Escherichia Coli Bacterin (USDA: 49K1.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000619 , obo:VO_0001220 , obo:VO_0002474 , obo:VO_0007748 .

obo:VO_0011128 a rdfs:Class ;
  rdfs:label "HA from Influenza B virus (B/Ibaraki/2/85)" ;
  rdfs:comment "Protection against a lethal influenza B virus infection was examined in BALB/c mice immunized with plasmid DNAs encoding hemagglutinin (HA), neuraminidase (NA and NB) and nucleoprotein (NP) from the B/Ibaraki/2/85 virus.  Both HA and NA DNAs conferred complete protection against the lethal challenge in all the tested mouse strains [PubMed: 11163667]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0000591 a rdfs:Class ;
  rdfs:label "vaccine protection assay" ;
  rdfs:comment "An assay that is used to detect if a vaccine protects a host against infection of virulent pathogen after vaccine immunization." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0002596 a rdfs:Class ;
  rdfs:label "guaB from Francisella tularensis" ;
  rdfs:comment "A guaB mutant is attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0000948 a rdfs:Class ;
  rdfs:label "Streptococcus equi vaccine" ;
  rdfs:comment "a bacterial vaccine against S. equi infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000772 .

obo:VO_0004566 a rdfs:Class ;
  rdfs:label "Marburg virus recombinant vector vaccine MBGV GP/MBGV NP" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012163 .

obo:VO_0001279 a rdfs:Class ;
  rdfs:label "parasite vaccine immunization" ;
  rdfs:subClassOf obo:VO_0000494 .

obo:VO_0001473 a rdfs:Class ;
  rdfs:label "parrot vaccine" ;
  rdfs:comment "Vaccine that used for immunizing parrot." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001461 .

obo:VO_0004817 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 UNT/ML [Rotarix]" ;
  rdfs:subClassOf obo:VO_0010738 .

obo:VO_0020914 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Agrippal]" ;
  rdfs:subClassOf obo:VO_0020913 .

obo:VO_0005186 a rdfs:Class ;
  rdfs:label "Covigenix VAX-001 vaccine" ;
  rdfs:comment "A prophylactic plasmid DNA Vaccine for SARS CoV-2 by Entos Pharmaceuticals" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0018607 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 700000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004820 .

obo:IAO_8000018 a rdfs:Class ;
  rdfs:label "obo basic subset ontology module"@en ;
  rdfs:comment """A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.

Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).

An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports"""@en ;
  rdfs:seeAlso <http://owlcollab.github.io/oboformat/doc/obo-syntax.html#6.2> ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:VO_0016314 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015930 .

obo:NCBITaxon_85708 a rdfs:Class ;
  rdfs:label "Porcine circovirus 2" ;
  rdfs:subClassOf obo:NCBITaxon_2732092 .

obo:VO_0004220 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus IsdB subunit vaccine (V710)" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0002502 .

obo:VO_0002158 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Conn Type, Live Virus Vaccine (USDA: 1762.13)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:DOID_4960 a rdfs:Class ;
  rdfs:label "bone marrow cancer"@en ;
  rdfs:comment "A hematopoietic cancer that derives_from the blood-forming stem cells of the bone marrow."@en ;
  rdfs:subClassOf obo:DOID_2531 .

obo:VO_0000650 a rdfs:Class ;
  rdfs:label "Rabies virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Rabies virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003545 .

obo:VO_0005265 a rdfs:Class ;
  rdfs:label "authorized COVID-19 RNA vaccine" ;
  rdfs:subClassOf obo:VO_0005198 , obo:VO_0005264 .

obo:VO_0011105 a rdfs:Class ;
  rdfs:label "HPV E7" ;
  rdfs:comment "Researchers combined the HPV16 E7 peptide(38-61) with a murine IgG heavy chain constant region to construct a chimeric protein compound.  The chimeric vaccine candidate was able to effectively protect mice against the challenge of HPV16-positive tumor cells, and to eradicate HPV16-expressing tumors in mice [PubMed: 15661238]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010786 .

obo:VO_0007070 a rdfs:Class ;
  rdfs:label "Recombinant Human Fusion Protein L19TNFalpha Vaccine" ;
  rdfs:comment "An immunocytokine consisting of human pro-inflammatory cytokine tumor necrosis factor alpha (TNFalpha) fused to a human single-chain variable fragment (scFv) directed against the extra-domain B (ED-B) of fibronectin (L19), with potential immunopotentiating and antineoplastic activities. Upon adinistration, the L19 moiety of onfekafusp alfa binds to the ED-B domain of fibronectin on tumor cells in the tumor neovasculature. In turn, the TNFalpha moiety may locally induce an immune response against ED-B fibronectin-expressing tumor cells and may specifically decrease the proliferation of ED-B-expressing tumor cells. ED-B is predominantly expressed during angiogenesis and tumor growth." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0005233 a rdfs:Class ;
  rdfs:label "mRNA-1273.351 vaccine" ;
  rdfs:comment "A SARS-CoV-2  lipid nanoparticle (LNP)-encapsulated mRNA-based vaccine that encodes for a full-length, prefusion stabilized S protein of the SARS-CoV-2 B.1.351 variant" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0020000 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0004493 a rdfs:Class ;
  rdfs:label "IPNV DNA vaccine pEGFP-N1-SegA and pEGFP-N1-VP2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003055 .

obo:VO_0018287 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003858 , obo:VO_0018273 .

obo:VO_0017500 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:VO_0000347 a rdfs:Class ;
  rdfs:label "Brucella abortus bacA mutant vaccine" ;
  rdfs:subClassOf obo:VO_0001134 .

obo:VO_0017912 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injectable Solution [Imuvac]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017818 .

obo:VO_0017698 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017697 .

obo:VO_0015276 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension [Havrix]" ;
  rdfs:subClassOf obo:VO_0003827 , obo:VO_0015275 .

obo:VO_0020748 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 4000000 ORGANISMS/ML [Bcg Medac]" ;
  rdfs:subClassOf obo:VO_0020747 .

obo:VO_0000348 a rdfs:Class ;
  rdfs:label "influenza A (H1N1) 2009 Monovalent vaccine (CSL Limited)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003211 , obo:VO_0010415 .

obo:VO_0003315 a rdfs:Class ;
  rdfs:label "Infanrix Tetra vaccine" ;
  rdfs:comment "A combination vaccine against diphtheria, tetanus, acellular pertussis, and inactivated poliomyelitis for individuals ages from 16 months to 13 years of age." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0018168 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution [Priorix] Box of 10" ;
  rdfs:subClassOf obo:VO_0018167 , obo:VO_0018170 .

obo:VO_0007357 a rdfs:Class ;
  rdfs:label "CD133 Antigen Peptide-pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted peptides derived from the CD133 antigen, with potential antineoplastic activity. Upon intradermal administration, the CD133 antigen peptide-pulsed autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against CD133-expressing tumor cells, resulting in tumor cell lysis. CD133, a cancer stem cell marker, is expressed on hematopoietic stem and progenitor cells and overexpressed on many types of cancer cells; it is associated with resistance to chemotherapy and increased cancer survival. HLA-A2 is an MHC class I molecule that presents antigenic peptides to CD8+ T-cells. Epitope design that is restricted to those epitopes that bind most efficiently to HLA-A2 may improve antigenic peptide immunogenicity." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:NCBITaxon_2732396 a rdfs:Class ;
  rdfs:label "Orthornavirae" ;
  rdfs:subClassOf obo:NCBITaxon_2559587 .

obo:VO_0016487 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0002625 a rdfs:Class ;
  rdfs:label "cobS from Salmonella Gallinarum" ;
  rdfs:comment "A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001420 .

obo:VO_0018871 a rdfs:Class ;
  rdfs:label "influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:VO_0016803 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Revaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0016726 , obo:VO_0016745 , obo:VO_0016819 .

obo:VO_0000387 a rdfs:Class ;
  rdfs:label "mucosal immune response to vaccine" ;
  rdfs:subClassOf obo:VO_0000408 .

obo:VO_0016963 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017420 .

obo:NCBITaxon_34085 a rdfs:Class ;
  rdfs:label "Riemerella anatipestifer" ;
  rdfs:subClassOf obo:NCBITaxon_200644 .

obo:VO_0000007 a rdfs:Class ;
  rdfs:label "Attenuvax vaccine" ;
  rdfs:comment "Product Name: Measles Virus Vaccine, Live" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000654 , obo:VO_0001220 , obo:VO_0010441 .

obo:VO_0018245 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 TCID / Mumps virus 12500 TCID / Rubella virus 1000 TCID" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0016338 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0005403 a rdfs:Class ;
  rdfs:label "RVM-V001 vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by RVAC Medicines" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0001112 a rdfs:Class ;
  rdfs:label "bovine parainfluenza virus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a bovine parainfluenza virus strain as vector" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0007493 a rdfs:Class ;
  rdfs:label "gp100:280-288 peptide vaccine" ;
  rdfs:comment "A vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. Vaccination with gp100:280-288 peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0018391 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe [Moniarix]" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0015814 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 25" ;
  rdfs:subClassOf obo:VO_0015496 .

obo:NCBITaxon_1224 a rdfs:Class ;
  rdfs:label "Pseudomonadota" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:VO_0001054 a rdfs:Class ;
  rdfs:label "Equilis StrepE vaccine" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000948 .

obo:VO_0017651 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0004168 a rdfs:Class ;
  rdfs:label "recombinant vesicular stomatitis virus encoding HA from Influenza A virus (A/WSN/1933(H1N1)) vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0003495 .

obo:VO_0003631 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016-2017 Formula Injection" ;
  rdfs:subClassOf obo:VO_0003628 .

obo:VO_0017590 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML [Pediacel]" ;
  rdfs:subClassOf obo:VO_0017682 .

obo:VO_0017146 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 2" ;
  rdfs:subClassOf obo:VO_0017129 , obo:VO_0017606 .

obo:NCBITaxon_10335 a rdfs:Class ;
  rdfs:label "Human alphaherpesvirus 3" ;
  rdfs:subClassOf obo:NCBITaxon_10319 .

obo:VO_0002318 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine-Escherichia Coli Bacterin (USDA: 49P1.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000619 , obo:VO_0001220 , obo:VO_0002470 , obo:VO_0007748 .

obo:VO_0000739 a rdfs:Class ;
  rdfs:label "Shigella ribosome-based vaccine (SRB)" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0003857 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010448 .

obo:VO_0011256 a rdfs:Class ;
  rdfs:label "VP7 from Murine rotavirus" ;
  rdfs:comment "Plasmid DNA vaccines encoding for murine rotaviral proteins VP4, VP6, and VP7 were tested in adult BALB/c mice for their ability to induce immune responses and provide protection against rotavirus challenge.  Vaccines  encoding VP7 were effective in protecting mice against infection after rotavirus (100 ID50) challenge [PubMed: 9015117]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010789 .

obo:VO_0020042 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Afluria 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020298 .

obo:VO_0004116 a rdfs:Class ;
  rdfs:label "defective adenovirus expressing VEEV E2 glycoprotein vaccine" ;
  rdfs:subClassOf obo:VO_0001499 .

obo:VO_0007205 a rdfs:Class ;
  rdfs:label "Adenovirus Encoding Tyrosinase/MART-1/MAGEA6-transduced Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a recombinant adenoviral vector encoding three full length human melanoma associated antigens (MAAs), tyrosinase, melan-A (MART-1) and the melanoma antigen A6 (MAGEA6), with potential antineoplastic activity. Upon intradermal administration, adenovirus encoding tyrosinase/MART-1/MAGEA6-transduced autologous DC vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tyrosinase/MART-1/MAGEA6-positive tumor cells, which may result in tumor cell death and decreased tumor growth. Tyrosinase, a melanoma-specific differentiation antigen, catalyzes the first step of melanin synthesis in melanocytes. Vaccination with multi-antigen modified DC may improve the efficacy of the DC immunotherapy." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0011427 a rdfs:Class ;
  rdfs:label "Classical swine fever virus vaccine VAC-E0" ;
  rdfs:subClassOf obo:VO_0001012 .

obo:VO_0019571 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003616 , obo:VO_0010427 , obo:VO_0019544 .

obo:VO_0000169 a rdfs:Class ;
  rdfs:label "Shigella gene" ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0019358 a rdfs:Class ;
  rdfs:label "0.7 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.0857 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:VO_0017042 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 50" ;
  rdfs:subClassOf obo:VO_0017032 , obo:VO_0017048 , obo:VO_0017512 .

obo:VO_0018584 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0018583 , obo:VO_0018688 .

obo:VO_0015637 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0003422 , obo:VO_0015549 .

obo:VO_0017671 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen (isoform M), recombinant 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0011008 a rdfs:Class ;
  rdfs:label "HtpG" ;
  rdfs:comment "Using a mouse plague model, YPO3119 (htpG) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0016810 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] Box of 25" ;
  rdfs:subClassOf obo:VO_0016729 , obo:VO_0016752 , obo:VO_0016826 .

obo:VO_0017494 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017489 , obo:VO_0017500 .

obo:VO_0004574 a rdfs:Class ;
  rdfs:label "BRSV DNA vaccine VCL-Fb" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001466 , obo:VO_0001507 .

obo:OBI_0000016 a rdfs:Class ;
  rdfs:label "regulation-assigned role"@en ;
  rdfs:comment "Regulation-assigned role is a regulatory role defined by legislation or governmental orders"@en ;
  rdfs:subClassOf obo:OBI_0000017 .

obo:VO_0000404 a rdfs:Class ;
  rdfs:label "Brucella abortus RB51WboA vaccine" ;
  rdfs:subClassOf obo:VO_0001134 .

obo:VO_0018349 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003337 .

obo:VO_0004384 a rdfs:Class ;
  rdfs:label "Ebola virus recombinant vector vaccine Ad-CAGoptZGP encoding the envelope glycoprotein" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000726 .

obo:VO_0019310 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML Prefilled Syringe [Fluzone High-Dose 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019308 , obo:VO_0020485 .

obo:VO_0016922 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 4 LFU/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension [Adacel]" ;
  rdfs:subClassOf obo:VO_0016921 , obo:VO_0017310 .

obo:VO_0004001 a rdfs:Class ;
  rdfs:label "Brucella melitensis omp25 mutant vaccine" ;
  rdfs:comment "A omp25 mutant is attenuated and provides protection against challenge in mice" ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0001039 a rdf:Property ;
  rdfs:label "has gene mutation" ;
  rdfs:comment "An object property that represents an organism has a mutation of a specific gene from the organism genome." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0016858 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016806 .

obo:VO_0020996 a rdfs:Class ;
  rdfs:label "Influenza Virus Vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0003504 .

obo:VO_0012183 a rdfs:Class ;
  rdfs:label "SARS vaccine" ;
  rdfs:comment "A vaccine that protects against SARS-CoV." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0004897 .

obo:VO_0019729 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluvirin 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003675 , obo:VO_0010427 , obo:VO_0019728 .

obo:VO_0000217 a rdfs:Class ;
  rdfs:label "obsolete pCMV4 DNA vaccine plasmid" .

obo:VO_0016731 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0016716 , obo:VO_0016735 .

obo:VO_0020530 a rdfs:Class ;
  rdfs:label "0.5 ML A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020683 .

obo:VO_0018492 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 20 by Merck" ;
  rdfs:subClassOf obo:VO_0018459 .

obo:VO_0010894 a rdfs:Class ;
  rdfs:label "PknD" ;
  rdfs:comment "IM-ID vaccination with CPn0095 (pknD) generated a response that resulted in moderately, but significantly reduced total C. pneumoniae lung loads as compared to control mice vaccinated with a plasmid expressing a non-Chlamydia ORF (p0.019).  This resulted in the ability of CPN0095 to mediate a moderate, but statistically significant level of protection in an inbred A/J mouse respiratory challenge model [PubMed: 16434129]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010794 .

obo:VO_0001437 a rdfs:Class ;
  rdfs:label "Human herpesvirus 1 gene" ;
  rdfs:comment "A viral gene that is from Human herpesvirus 1." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0020210 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.0075 MG/ML / SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (BA.4/BA.5) 0.0075 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0002880 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium cya/crp mutant vaccine" ;
  rdfs:comment "A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium" .

obo:VO_0002838 a rdfs:Class ;
  rdfs:label "E. coli ler mutant vaccine" ;
  rdfs:comment "A ler deletion mutant derived from wild-type EHEC O157:H7 86-24 was constructed by use of suicide vector pCVD442. Following challenge of 7-day-old suckling mice with O157:H7 EDL933, 75.2% born to group B mothers (immunized with F25) sur- vived, as did 83.0% born to group C mothers (immunized with F105). The surviving suckling mice consistently gained body weight. Only 16.8% of sucking mice born to control group mice survived the challenge" ;
  rdfs:subClassOf obo:VO_0000962 .

obo:VO_0016215 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0002116 a rdfs:Class ;
  rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine (USDA: 1475.00)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002424 , obo:VO_0007748 .

obo:VO_0018100 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Prefilled Syringe [Priorix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018099 , obo:VO_0018102 , obo:VO_0018235 .

obo:VO_0003482 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010304 , obo:VO_0010415 .

obo:VO_0007312 a rdfs:Class ;
  rdfs:label "Autologous Pluripotent ALDHbr Stem Cells ALD-451 Vaccine" ;
  rdfs:comment "A specific population of autologous, pluripotent bone marrow derived cells that express high levels of the cytosolic enzyme aldehyde dehydrogenase (ALDH) with potential protective and neuro-cognition improving activity. Expression of high levels of ALDH is an indicator of the biological activity in heterogenous early stage stem cells. Upon intravenous administration, these ALDH bright cells may protect normal cells and may repair damaged cells. These cells may also protect brain cells from damage and may improve neurocognition." ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0018614 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000665 , obo:VO_0010440 .

obo:VO_0020658 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] Box of 3" ;
  rdfs:subClassOf obo:VO_0020657 , obo:VO_0020704 .

obo:VO_0015320 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Prefilled Syringe [Havpur]" ;
  rdfs:subClassOf obo:VO_0003432 .

obo:VO_0004099 a rdfs:Class ;
  rdfs:label "pABFHc2 vaccine" ;
  rdfs:subClassOf obo:VO_0012187 .

obo:VO_0002281 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine-Salmonella Enteritidis Bacterin (USDA: 48D6.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002453 , obo:VO_0007748 .

obo:VO_0017153 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017611 .

obo:VO_0020535 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML Injectable Solution [HibTITER] Box of 5" ;
  rdfs:subClassOf obo:VO_0020534 , obo:VO_0020537 , obo:VO_0020829 .

obo:VO_0010069 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi ASP-1" ;
  rdfs:comment "A ASP-1 protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0003920 a rdfs:Class ;
  rdfs:label "Fluad 2016-2017 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003911 .

obo:VO_0015167 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015164 .

obo:VO_0020915 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Fluarix]" ;
  rdfs:subClassOf obo:VO_0000045 , obo:VO_0020913 .

obo:VO_0001557 a rdfs:Class ;
  rdfs:label "Anthrax Spore live culture Vaccine (USDA: 1011.00)" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 .

obo:VO_0004734 a rdfs:Class ;
  rdfs:label "ALVAC-NiV-F vaccine" ;
  rdfs:subClassOf obo:VO_0012169 .

obo:VO_0018652 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML [Cervarix]" ;
  rdfs:subClassOf obo:VO_0011559 , obo:VO_0018797 .

obo:VO_0010907 a rdfs:Class ;
  rdfs:label "Bfr from B. abortus S19" ;
  rdfs:comment "Following two intragastric immunizations in BALB/c mice, the Yersinia vectors harboring a DNA vaccine encoding BFR (P39) induced antigen-specific serum immunoglobulin and Th1-type responses among splenocytes. The best protection was conferred by a serotype O:9 strain carrying pCIP39, confirming the importance of the P39 T-cell antigen in this mechanism [PubMed: 11895955]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0007418 a rdfs:Class ;
  rdfs:label "MSCV-MGMT(P140K) vaccine" ;
  rdfs:comment "Gene name: MGMT" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0017526 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017521 .

obo:VO_0007614 a rdfs:Class ;
  rdfs:label "HSP65-HER2 fusion peptide vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0000029 a rdfs:Class ;
  rdfs:label "Daptacel vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0015770 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015594 .

obo:VO_0016422 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015967 .

obo:VO_0001853 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 16D5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0002436 , obo:VO_0007748 .

obo:VO_0020062 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Agriflu 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0001176 , obo:VO_0004914 , obo:VO_0020307 .

obo:VO_0019403 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 8 UNT/ML / diphtheria toxoid vaccine, inactivated 13.4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017799 , obo:VO_0018770 .

obo:VO_0017905 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Menjugate]" ;
  rdfs:subClassOf obo:VO_0017848 .

obo:VO_0020904 a rdfs:Class ;
  rdfs:label "Influenza A virus / Influenza B virus Injectable Suspension [Alpha RIX Tetra]" ;
  rdfs:subClassOf obo:VO_0020903 .

obo:VO_0003507 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003500 , obo:VO_0010415 .

obo:VO_0016612 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0016562 , obo:VO_0016617 .

obo:VO_0017654 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0003066 a rdfs:Class ;
  rdfs:label "Bexsero vaccine" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000534 , obo:VO_0000714 , obo:VO_0010293 , obo:VO_0010295 , obo:VO_0010444 .

obo:VO_0003586 a rdfs:Class ;
  rdfs:label "Fluzone 2016-2017 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003584 .

obo:VO_0001145 a rdfs:Class ;
  rdfs:label "vaccine organism live" ;
  rdfs:comment "vaccine being viable is a vaccine viability that indicates a vaccine uses live organism." ;
  rdfs:subClassOf obo:VO_0001139 .

obo:VO_0003116 a rdfs:Class ;
  rdfs:label "TD-Rix vaccine" ;
  rdfs:comment "A vaccine used to prevent diphtheria and tetanus in individuals over 6 years of age." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0011314 a rdfs:Class ;
  rdfs:label "F fusion protein from Nipah virus" ;
  rdfs:comment "Hamsters were immunized subcutaneously with either 10^7 PFU of VV-NiV.G or VV-NiV.F expressing the G and F glycoproteins, respectively, or with the two combined.  When the VV-NiV.F-vaccinated animals were challenged with Nipah virus 3 months after the last immunization (1,000 PFU/animal intraperitoneally), there was complete protection against mortality [PubMed: 14694115]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010845 .

obo:VO_0001661 a rdfs:Class ;
  rdfs:label "Chicken Anemia Virus Live Virus Vaccine (USDA: 10A1.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001510 , obo:VO_0007748 .

obo:VO_0000977 a rdfs:Class ;
  rdfs:label "enterohemorrhagic E. coli vaccine" ;
  rdfs:comment "An E. coli vaccine against enterohemorrhagic E. coli infections" ;
  rdfs:subClassOf obo:VO_0000041 .

obo:VO_0007733 a rdfs:Class ;
  rdfs:label "sialyl lewis-keyhole limpet hemocyanin conjugate vaccine" ;
  rdfs:comment "A cancer vaccine that consists of the oligosaccharide antigen sialyl Lewis (CA19-9) conjugated to the nonspecific immunomodulator keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. The sialyl Lewis-keyhole limpet hemocyanin conjugate vaccine may induce production of IgG and IgM antibodies as well as trigger an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing the sialyl Lewis antigen. The vaccine therapy together with QS21 may cause a stronger immune response and kill more tumor cells. " ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0007657 .

obo:VO_0000926 a rdfs:Class ;
  rdfs:label "human albumin cell culture residual in vaccine" ;
  rdfs:comment "a cell culture residual in vaccine that is human albumin." ;
  rdfs:subClassOf obo:VO_0000856 .

obo:VO_0001899 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002343 .

obo:VO_0001848 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002434 , obo:VO_0007748 .

obo:VO_0017170 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] by Novartis" ;
  rdfs:subClassOf obo:VO_0017163 .

obo:BFO_0000029 a rdfs:Class ;
  rdfs:label "site"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:VO_0017345 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017344 .

obo:VO_0019458 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Decavac]" ;
  rdfs:subClassOf obo:VO_0000030 , obo:VO_0019457 .

obo:VO_0019283 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0018562 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection [Typherix]" ;
  rdfs:subClassOf obo:VO_0018561 , obo:VO_0018718 .

obo:VO_0007725 a rdfs:Class ;
  rdfs:label "personalized neoantigen melanoma vaccine" ;
  rdfs:comment "A cancer vaccine for melanoma. Melanomas have mutations (changes in genetic material) that are specific to an individual patient and tumor. These mutations can cause the tumor cells to produce proteins that appear very different from the body's own cells. These proteins used in a vaccine may induce strong immune responses, which may help the participant's body fight any tumor cells that could cause the melanoma to come back in the future. NeoVax is a long-peptide vaccine targeting up to 20 personal neoantigens per patient for patients with surgically resected stage IIIB/C or IVM1a/b melanoma. There was long-term persistence of neoantigen-specific T cell responses following vaccination, with ex vivo detection of neoantigen-specific T cells exhibiting a memory phenotype, as well as diversification of neoantigen-specific T cell clones over time, with emergence of multiple T cell receptor clonotypes exhibiting distinct functional avidities. There was also tumor infiltration by neoantigen-specific T cell clones after vaccination and epitope spreading, suggesting on-target vaccine-induced tumor cell killing. Personal neoantigen peptide vaccines thus induce T cell responses that persist over years and broaden the spectrum of tumor-specific cytotoxicity in patients with melanoma. " ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0011386 a rdfs:Class ;
  rdfs:label "A. salmonicida live-attenuated vaccine encoding AroA" ;
  rdfs:comment "The aroA gene was inactivated by inserting a fragment expressing kanamycin resistance within the coding sequence and challenged in fish. The LD50 for unvaccinated fish was 71. In contrast, the LD50 was 1.8 x 104 in fish vaccinated once and 3 x 105 in fish vaccinated twice" ;
  rdfs:subClassOf obo:VO_0000820 , obo:VO_0001217 .

obo:VO_0002669 a rdfs:Class ;
  rdfs:label "obsolete aroA from Shigella" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" .

obo:VO_0003266 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0015020 .

obo:VO_0019642 a rdfs:Class ;
  rdfs:label "influenza A virus (H5N1) antigen Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0017779 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017777 , obo:VO_0017799 .

obo:VO_0005064 a rdfs:Class ;
  rdfs:label "pRc/RSV DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pRc/RSV.  This plasmid is 5224 base pairs in length and contains a RSV LTR promoter and ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015081 a rdfs:Class ;
  rdfs:label "Fluzone 2015-2016 Injectable Product" ;
  rdfs:subClassOf obo:VO_0015080 .

obo:VO_0017826 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.008 MG/ML / meningococcal group C polysaccharide 0.008 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.008 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.008 MG/ML [Menactra]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017812 .

obo:VO_0002666 a rdfs:Class ;
  rdfs:label "znuB from Salmonella Typhimurium" ;
  rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:NCBITaxon_33340 a rdfs:Class ;
  rdfs:label "Neoptera" ;
  rdfs:subClassOf obo:NCBITaxon_1206794 .

obo:IAO_0000001 a rdfs:Class ;
  rdfs:label "conditional specification"@en ;
  rdfs:comment "A directive information entity that specifies what should happen if the trigger condition is fulfilled."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:VO_0004762 a rdfs:Class ;
  rdfs:label "rLSDV-Rabies-gP vaccine" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:NCBITaxon_11120 a rdfs:Class ;
  rdfs:label "Infectious bronchitis virus" ;
  rdfs:subClassOf obo:NCBITaxon_2501931 .

obo:VO_0004348 a rdfs:Class ;
  rdfs:label "HIV DNA vaccine pHIS-SHIV-B" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0015726 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat] Box of 1" ;
  rdfs:subClassOf obo:VO_0015575 , obo:VO_0015794 .

obo:NCBITaxon_562 a rdfs:Class ;
  rdfs:label "Escherichia coli" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:VO_0020903 a rdfs:Class ;
  rdfs:label "Influenza A virus / Influenza B virus Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0002373 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Vaccine-Leptospira Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0002372 .

obo:VO_0016305 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015926 .

obo:VO_0018577 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0018570 , obo:VO_0018766 .

obo:VO_0000203 a rdfs:Class ;
  rdfs:label "Suvaxyn PCV2 vaccine" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001524 .

obo:VO_0004498 a rdfs:Class ;
  rdfs:label "avian influenza virus DNA vaccine pN1NA encoding N1 neuraminidase" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0005413 a rdfs:Class ;
  rdfs:label "GEMCOVAC-19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine by Gennova Biopharmaceuticals Limited" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0020584 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Preflucel] Box of 10" ;
  rdfs:subClassOf obo:VO_0020583 , obo:VO_0020603 , obo:VO_0020875 .

obo:VO_0002595 a rdfs:Class ;
  rdfs:label "guaA from Francisella tularensis" ;
  rdfs:comment "A guaA mutant is highly attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0018844 a rdfs:Class ;
  rdfs:label "oral suspension" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:VO_0015504 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0003257 .

obo:VO_0017086 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Covaxis] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017085 .

obo:VO_0004229 a rdfs:Class ;
  rdfs:label "Eimeria maxima oocysts with Arlacel A vaccine" ;
  rdfs:subClassOf obo:VO_0001125 .

obo:VO_0001681 a rdfs:Class ;
  rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.14)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000985 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0000376 a rdfs:Class ;
  rdfs:label "subtenon route" ;
  rdfs:comment "A route of administration that is through the membrane covering the muscles and nerves at the back of the eyeball" ;
  rdfs:seeAlso <http://ncim.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20MetaThesaurus&code=CL426248> ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0017722 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 50 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017721 .

obo:VO_0004250 a rdfs:Class ;
  rdfs:label "attenuated Listeria expressing cancer antigen vaccine" ;
  rdfs:comment "Gene name: E7" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000484 , obo:VO_0005488 , obo:VO_0007657 .

obo:VO_0002362 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Haemophilus Somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0002361 .

obo:VO_0020295 a rdfs:Class ;
  rdfs:label "yellow fever virus strain 17D-204 live antigen 2000 UNT/ML Injection [Stamaril]" ;
  rdfs:subClassOf obo:VO_0020294 .

obo:VO_0002917 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium znuABC mutant vaccine" ;
  rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" .

obo:VO_0020361 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML [Typhim V]" ;
  rdfs:subClassOf obo:VO_0003855 .

obo:VO_0020181 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (human), inactivated Injection [Imovax]" ;
  rdfs:subClassOf obo:VO_0020180 .

obo:VO_0017986 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 2.5 MG / meningococcal group C polysaccharide 2.5 MG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 2.5 MG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 2.5 MG Injectable Solution by Aventis" ;
  rdfs:subClassOf obo:VO_0017957 .

obo:VO_0001274 a rdfs:Class ;
  rdfs:label "vaccine recipient role" ;
  rdfs:comment "Role that inheres in an organism that is the target of a vaccine administration (vaccination process)." ;
  rdfs:subClassOf obo:OBI_0000444 .

obo:RO_0000052 a rdf:Property ;
  rdfs:label "characteristic of"@en ;
  rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002314 .

obo:VO_0006038 a rdfs:Class ;
  rdfs:label "Novel influenza-H1N1-09 injectable" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0010415 .

obo:VO_0016001 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0003427 , obo:VO_0015787 .

obo:VO_0017318 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus B Conjugate Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0017669 , obo:VO_0020836 .

obo:VO_0011106 a rdfs:Class ;
  rdfs:label "HPV L2" ;
  rdfs:comment "Antibody responses of mice (n = 120) and rabbits (n = 23) to vaccination with HPV-16 amino-terminal L2 polypeptides or multitype L2 fusion proteins were compared.  11-200 x 3 formulated in GPI-0100 adjuvant or alum with 1018 ISS protected mice against HPV-16 challenge (reduction in HPV-16 infection vs phosphate-buffered saline control, P < .001) 4 months after vaccination as well as HPV-16 L1 VLPs [PubMed: 19470949]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010786 .

obo:DOID_363 a rdfs:Class ;
  rdfs:label "uterine cancer"@en ;
  rdfs:comment "A female reproductive organ cancer that is located_in the uterus."@en ;
  rdfs:subClassOf obo:DOID_120 , obo:DOID_345 .

obo:VO_0002214 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4639.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002409 , obo:VO_0007748 .

obo:VO_0007603 a rdfs:Class ;
  rdfs:label "ESAT-6-gpi DNA vaccine combined with B16F10-ESAT-6-gpi/IL-21 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0016140 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Europharma" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0001601 a rdfs:Class ;
  rdfs:label "avian influenza H5N3 Subtype, Killed Virus Vaccine (USDA: 1057.R3)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0015039 a rdfs:Class ;
  rdfs:label "Gardasil 9 prefilled syringe" ;
  rdfs:subClassOf obo:VO_0015038 .

obo:VO_0016403 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 3 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015960 , obo:VO_0015966 .

obo:VO_0017584 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 5.33 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017583 .

obo:VO_0000552 a rdfs:Class ;
  rdfs:label "attenuated Mycobacterium bovis strain WAg520 vaccine" ;
  rdfs:subClassOf obo:VO_0000077 , obo:VO_0001217 .

obo:VO_0011409 a rdfs:Class ;
  rdfs:label "Hendra virus G protein vaccine" ;
  rdfs:subClassOf obo:VO_0012170 .

obo:VO_0000365 a rdfs:Class ;
  rdfs:label "lipopolysaccharide of pathogen organism as vaccine component" ;
  rdfs:subClassOf obo:VO_0000000 .

obo:VO_0010755 a rdfs:Class ;
  rdfs:label "parasite protein" ;
  rdfs:comment "a protein from a parasite" ;
  rdfs:subClassOf obo:PR_000000001 .

obo:VO_0007268 a rdfs:Class ;
  rdfs:label "anti-p53 T-Cell Receptor-Transduced peripheral blood lymphocytes vaccine" ;
  rdfs:comment "Human autologous peripheral blood lymphocytes (PBLs) transduced with an anti-p53 T cell receptor gene with potential antineoplastic activity. PBLs are harvested from a patient and pulsed with a retroviral vector that encodes the T-cell receptor gene specific for a mutated form of p53. The transduced PBLs are then expanded in culture. When reintroduced to the patient, these modified PBLs express the anti-p53 T cell receptor which binds to mutant p53-overexpressing tumor cells; PBL-mediated tumor growth inhibition may follow. Many tumor cell types overexpress mutant p53 proteins, which are associated with the loss of apoptosis regulation and abnormal cell proliferation." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0019500 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003431 .

obo:VO_0007390 a rdfs:Class ;
  rdfs:label "IDH1R132H-Specific Peptide Vaccine PEPIDH1M" ;
  rdfs:comment "A peptide vaccine consisting of a peptide derived from isocitrate dehydrogenase 1 (IDH1) containing the point mutation R132H (IDH1R132H), with potential antineoplastic activity. Intradermal vaccination with the IDH1R132H-specific peptide vaccine PEPIDH1M may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express the IDH1R132H protein. The IDH1 point mutation of amino acid residue 132 is highly expressed in gliomas and is associated with increased production of the oncometabolite R-2-hydroxyglutarate" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0010986 a rdfs:Class ;
  rdfs:label "IutA" ;
  rdfs:comment "Immunization with IutA protects against urinary tract colinization by E.coli CFT073 in the bladders of CBA/J mice [PubMed: 19806177]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0004416 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine pDNA encoding PA" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0001808 a rdfs:Class ;
  rdfs:label "Pseudorabies Modified Live Virus Vaccine (USDA: 1891.R2)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000750 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0005464 a rdfs:Class ;
  rdfs:label "Non-US bivalent oral polio vaccine (types 1 and 3)" ;
  rdfs:comment "A poliovirus vaccine that contains two types of poliovirus and uses poliovirus particles that have been grown under controlled conditions and then killed to prevent disease caused from the vaccine." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 .

obo:VO_0018248 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT / Varicella Virus Vaccine Live (Oka-Merck) strain 1000 UNT" ;
  rdfs:subClassOf obo:VO_0000737 .

obo:VO_0000639 a rdfs:Class ;
  rdfs:label "Clostridium vaccine" ;
  rdfs:comment "A bacterial vaccine that protects against infection with Clostridium spp." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003554 .

obo:VO_0016989 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 10 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016988 .

obo:VO_0021129 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:VO_0016176 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0017138 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017133 , obo:VO_0017147 , obo:VO_0017601 .

obo:VO_0011527 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus DNA vaccine encoding CAB613" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001085 .

obo:VO_0016944 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0019452 .

obo:VO_0001491 a rdfs:Class ;
  rdfs:label "Bovine papillomavirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Bovine papillomavirus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003538 .

obo:VO_0007252 a rdfs:Class ;
  rdfs:label "Amolimogene Bepiplasmid Vaccine" ;
  rdfs:comment "A plasmid DNA-based vaccine consisting of small biodegradable poly(lactide-co-glicolide) polymer microparticles encapsulating plasmid-DNA vector encoding a chimeric protein comprising epitopes derived from the E6 and E7 oncoproteins of the human papillomavirus (HPV) types 16 and 18, with potential antineoplastic activity. Upon intramuscular vaccination, amolimogene bepiplasmid may elicit the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV-16 and -18 E6 and E7 and may result in a reduction in tumor cell growth. HPV types 16 and 18 oncoproteins E6 and E7 are most commonly involved in cervical cancer." ;
  rdfs:subClassOf obo:VO_0005488 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0001167 a rdfs:Class ;
  rdfs:label "KLH-s-FimH1-25 with CFA and then IFA vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0002611 a rdfs:Class ;
  rdfs:label "obsolete siaD from Neisseria meningitidis" ;
  rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" .

obo:VO_0020101 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.0000000385 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018800 , obo:VO_0020099 .

obo:VO_0003002 a rdfs:Class ;
  rdfs:label "Western equine encephalomyelitis virus PE2/E2 mutant virus" ;
  rdfs:comment "A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ;
  rdfs:subClassOf obo:VO_0012188 .

obo:VO_0010434 a rdfs:Class ;
  rdfs:label "licensed human bacillus anthracis vaccine" ;
  rdfs:comment "Bacillus anthracis vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000635 .

obo:VO_0001784 a rdfs:Class ;
  rdfs:label "Streptococcus Equi Live Culture Vaccine (USDA: 1831.00)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000948 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0012383 a rdfs:Class ;
  rdfs:label "phpA-79" ;
  rdfs:comment "Immunization with rPhpA-79 protein adjuvanted with monophosphoryl lipid A (for subcutaneous immunization) or a mutant cholera toxin, CT-E29H (for intranasal immunization), protected CBA/N mice against death and bacteremia, as well as reduced nasopharyngeal colonization, following intranasal challenge with a heterologous pneumococcal strain [PubMed: 11349048]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0001029 a rdfs:Class ;
  rdfs:label "autologous dendritic cell melanoma vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0017271 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.008 MG / Bordetella pertussis 0.05 MG / diphtheria toxoid vaccine, inactivated 30 UNT / tetanus toxoid vaccine, inactivated 40 UNT [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0018774 .

obo:VO_0016295 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0016027 .

obo:VO_0018354 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003339 .

obo:VO_0018123 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella virus vaccine Injection [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0000069 , obo:VO_0018122 .

obo:VO_0007572 a rdfs:Class ;
  rdfs:label "Ad5-yCD/mutTKSR39rep-hIL12 vaccine" ;
  rdfs:comment "A replication-competent oncolytic adenovirus encoding the murine pro-inflammatory cytokine interleukin-12 (IL-12) gene and two suicide fusion genes, a yeast cytosine deaminase (yCD) and a mutant form of herpes simplex virus type 1 thymidine kinase (HSV-1 TKSR39), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration of Ad5-yCD/mutTKSR39rep-hIL12, the adenovirus selectively infects and replicates in tumor cells, which results in direct tumor cell lysis. Synergistically, IL-12 expressed by the adenovirus may activate the immune system by promoting the activation of natural killer cells (NKs), inducing secretion of interferon-gamma (IFN-g) and inducing cytotoxic T-lymphocyte (CTL) responses against tumor cells, which may result in immune-mediated tumor cell death, inhibition of tumor cell proliferation and inhibition of tumor angiogenesis. In addition, Ad5-yCD/mutTKSR39rep-hIL12-infected cancer cells express yCD and TKSR39; upon administration of the prodrugs 5-fluorocytosine (5-FC) and valganciclovir (vGCV), the yCD and HSV-1 TKSR39 activate these prodrugs to form 5-fluorouracil (5-FU) and ganciclovir, respectively. 5-FU gets converted to 5-fluoro-uridine monophosphate (5-FUMP) and subsequently to 5-fluoro-deoxyuridine monophosphate (5-FdUMP); 5-FdUMP irreversible inhibits thymidylate synthase, inhibits deoxythymidine triphosphate (dTTP) formation and halts DNA synthesis. Once phosphorylated intracellularly, ganciclovir triphosphate competitively inhibits deoxyguanosine triphosphate (dGTP) incorporation into DNA and inhibits DNA synthesis." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0015690 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015566 , obo:VO_0015776 .

obo:VO_0011488 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni DNA vaccine pcDNA3.1(+)-peblA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012182 .

obo:VO_0015792 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 3" ;
  rdfs:subClassOf obo:VO_0015491 .

obo:VO_0016825 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0016734 , obo:VO_0016774 .

obo:VO_0017064 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution [Tetamun] Box of 10" ;
  rdfs:subClassOf obo:VO_0017062 , obo:VO_0017066 , obo:VO_0017541 .

obo:VO_0017244 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Hepatitis B Surface Antigen Vaccine / tetanus toxoid vaccine, inactivated Prefilled Syringe [Anrix]" ;
  rdfs:subClassOf obo:VO_0017243 .

obo:VO_0003698 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0000983 , obo:VO_0010432 .

obo:VO_0016110 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015872 .

obo:DOID_14566 a rdfs:Class ;
  rdfs:label "disease of cellular proliferation"@en ;
  rdfs:comment "A disease that is characterized by abnormally rapid cell division."@en ;
  rdfs:subClassOf obo:DOID_4 .

obo:VO_0019374 a rdfs:Class ;
  rdfs:label "1.5 ML hepatitis B surface antigen vaccine 0.02 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015496 .

obo:VO_0003716 a rdfs:Class ;
  rdfs:label "Afluria 2015-2016 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003715 .

obo:VO_0020932 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Fluvax]" ;
  rdfs:subClassOf obo:VO_0003216 , obo:VO_0020929 .

obo:VO_0018327 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0018318 .

obo:VO_0005508 a rdfs:Class ;
  rdfs:label "Bl-Eng2+Adjuplex vaccine adjuvant" ;
  rdfs:comment "Combination vaccine adjuvant contains both Bl-Eng2 and adjuplex vaccine adjuvants and is able to induce a mixed Th1/Th2 response." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0001224 a rdfs:Class ;
  rdfs:label "Viral hemorrhagic septicemia virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Viral hemorrhagic septicemia virus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0020964 a rdfs:Class ;
  rdfs:label "Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0003526 .

obo:VO_0004591 a rdfs:Class ;
  rdfs:label "Plasmodium berghei DNA vaccine encoding PbCSP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002513 .

obo:VO_0016395 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0020465 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10 by Waymade" .

obo:VO_0016012 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 1" ;
  rdfs:subClassOf obo:VO_0003262 .

obo:VO_0003435 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injection" ;
  rdfs:subClassOf obo:VO_0003430 .

obo:VO_0001000 a rdfs:Class ;
  rdfs:label "pSCA1 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pSCA1." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0010350 a rdfs:Class ;
  rdfs:label "Influenza Virus Vaccine, H5N1 (for National Stockpile)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0016021 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015664 , obo:VO_0015819 .

obo:VO_0003687 a rdfs:Class ;
  rdfs:label "Fluvirin 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000046 , obo:VO_0010433 .

obo:VO_0019597 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Nasal Spray [FluMist Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019592 , obo:VO_0020351 .

obo:VO_0020316 a rdfs:Class ;
  rdfs:label "Fluarix 2012-2013 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000045 , obo:VO_0000578 , obo:VO_0010418 .

obo:VO_0015737 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 100" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015802 .

obo:VO_0001872 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calicivirus Modified Live Virus Vaccine (USDA: 16C1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001220 , obo:VO_0002440 , obo:VO_0007748 .

obo:VO_0003322 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 19A vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003223 .

obo:VO_0010202 a rdfs:Class ;
  rdfs:label "meningococcal polysaccharide (groups A, C, Y and W-135) diphtheria toxoid conjugate vaccine (MCV4P)" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0016501 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:VO_0016436 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by HVD" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0000780 a rdfs:Class ;
  rdfs:label "GP-VRP vaccine" ;
  rdfs:comment "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus GP protein." ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0017881 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0015069 .

obo:VO_0002979 a rdfs:Class ;
  rdfs:label "Infectious Hematopoietic Necrosis Virus NV mutant vaccine" ;
  rdfs:comment "A mutation in the non-virion protein of IHNV causes attenuated growth in rainbow trout and is able to provide significant protection from subsequent challenge with wild type IHNV" ;
  rdfs:subClassOf obo:VO_0012165 .

obo:VO_0018638 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injectable Suspension [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0018613 , obo:VO_0018800 .

obo:VO_0020091 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine B/Brisbane/60/2008 antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003523 .

obo:VO_0004696 a rdfs:Class ;
  rdfs:label "PAV3-HA (A/Hanoi/30408/2005 H5N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0003293 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003341 .

obo:VO_0018629 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 1 UNT Injectable Suspension [Je-Vax]" ;
  rdfs:subClassOf obo:VO_0018627 , obo:VO_0018628 , obo:VO_0020105 .

obo:VO_0002585 a rdfs:Class ;
  rdfs:label "slyA from Edwardsiella tarda" ;
  rdfs:comment "An aroC and slyA mutant is attenuated in zebra fish. This mutant is also protective against challenge from wild type E. tarda, resulting in a relative percent survival of 80.1%" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001413 .

obo:VO_0007736 a rdfs:Class ;
  rdfs:label "total tumor RNA-loaded dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine containing autologous dendritic cells (DCs) that are loaded with total tumor RNA (TTRNA) from a specific tumor, with potential immunostimulatory and antineoplastic activities. The vaccine may elicit a highly specific cytotoxic T-cell (CTL) response against the tumor-associated antigens (TAAs) encoded by the TTRNA. The vaccine can be given in combination with Temozolomide (TMZ) and Autologous Hematopoietic Stem Cells (HSC)." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0021137 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:VO_0016335 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0017837 a rdfs:Class ;
  rdfs:label "influenza B virus antigen, Hong Kong 330-2001 / meningococcal group C polysaccharide Injectable Solution [Menitorix]" ;
  rdfs:subClassOf obo:VO_0017889 .

obo:VO_0003088 a rdfs:Class ;
  rdfs:label "Boostrix-Polio vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000742 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0010795 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0004864 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0004860 .

obo:VO_0017125 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017581 .

obo:VO_0021101 a rdfs:Class ;
  rdfs:label "influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017512 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 50" ;
  rdfs:subClassOf obo:VO_0017507 , obo:VO_0017517 .

obo:VO_0007096 a rdfs:Class ;
  rdfs:label "PEP-3-KLH conjugate vaccine" ;
  rdfs:comment "A cancer vaccine consisting of PEP-3, a synthetic peptide encompassing a tumor-specific mutated segment of the epidermal growth factor receptor type vIII (EGFRvIII), conjugated to the naturally-occurring immunoadjuvant keyhole limpet hemocyanin (KLH) with potential immunostimulating and antineoplastic activities. Upon administration, PEP-3-KLH conjugate vaccine may induce a cytotoxic immune response against tumor cells that overexpress EGFRvIII; this antitumoral immune response may involve antibody-dependent cellular cytotoxicity (ADCC)." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0015876 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [H-B-Vax II] Box of 10" ;
  rdfs:subClassOf obo:VO_0015616 , obo:VO_0016001 .

obo:VO_0018498 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018464 .

obo:VO_0015717 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 100" ;
  rdfs:subClassOf obo:VO_0015572 , obo:VO_0015796 .

obo:VO_0002658 a rdfs:Class ;
  rdfs:label "rpoS from Salmonella Typhimurium" ;
  rdfs:comment "Immunizations with Salmonella typhimurium rpoS and rpoS aroA mutants protected susceptible BALB/c mice against subsequent oral challenge with virulent S. typhimurium. When administered orally or intraperitoneally, rpoS derivatives of the mouse-virulent S. typhimurium strains, C52 and SL1344, were highly attenuated and were efficient single-dose live vaccines" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0019255 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010433 .

obo:VO_0017697 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] Box of 10" ;
  rdfs:subClassOf obo:VO_0017696 , obo:VO_0017704 , obo:VO_0017748 .

obo:VO_0001617 a rdfs:Class ;
  rdfs:label "Bronchitis Georgia Type, Live Virus Vaccine (USDA: 1231.1J)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:NCBITaxon_10508 a rdfs:Class ;
  rdfs:label "Adenoviridae" ;
  rdfs:subClassOf obo:NCBITaxon_2732005 .

obo:VO_0018909 a rdfs:Class ;
  rdfs:label "influenza B virus B/Austria/1359417/2021 antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0001543 a rdfs:Class ;
  rdfs:label "Feline immunodeficiency virus Killed Virus Vaccine (USDA: 15A5.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001508 , obo:VO_0007748 .

obo:VO_0016482 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0018015 a rdfs:Class ;
  rdfs:label "poliomyelitis virus type 1 brunhilde 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML [Poliovaccine Ssi]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018047 .

obo:VO_0019653 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Afluria Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0020303 .

obo:VO_0004194 a rdfs:Class ;
  rdfs:label "P. chabaudi AMA1 Protein Vaccine" ;
  rdfs:subClassOf obo:VO_0000761 .

obo:VO_0004588 a rdfs:Class ;
  rdfs:label "REV DNA vaccine VP22/gag and VP22/env" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002544 .

obo:VO_0016187 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:NCBITaxon_10326 a rdfs:Class ;
  rdfs:label "Equid alphaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_10319 .

obo:VO_0019940 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003611 .

obo:VO_0011218 a rdfs:Class ;
  rdfs:label "P. falciparum CSP" ;
  rdfs:comment "A P. berghei parasite line was used to expresses a heterologous circumsporozoite protein (CSP) from P. falciparum. A sterile immunity was obtained  by vaccination with the radiation-attenuated P. berghei parasite [PubMed: 18159254]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:OBI_0000576 a rdfs:Class ;
  rdfs:label "scattered molecular aggregate"@en ;
  rdfs:comment "a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000643 a rdf:Property ;
  rdfs:label "has grain" ;
  rdfs:comment "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car."@en ;
  rdfs:range obo:CHEBI_23367 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:VO_0003048 a rdfs:Class ;
  rdfs:label "vaccine-induced herd immunity" ;
  rdfs:comment "when the vaccination of a significant portion of a population (or herd), in contagious diseases that are transmitted from individual to individual, chains of infection are likely to be disrupted, so the large numbers of a population are immue or less susceptible to the disease. " ;
  rdfs:subClassOf obo:VO_0000288 .

obo:VO_0020721 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017679 .

obo:VO_0003356 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 2000000000 UNT Delayed Release Oral Capsule [Vivotif]" ;
  rdfs:subClassOf obo:VO_0003354 .

obo:VO_0020445 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1" .

obo:VO_0002297 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae Bacterin (USDA: 4993.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002478 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0010225 a rdfs:Class ;
  rdfs:label "cholera, WC-rBS" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010455 .

obo:VO_0001285 a rdfs:Class ;
  rdfs:label "Algal Glucan vaccine adjuvant" ;
  rdfs:comment "A carbohydrate vaccine adjuvant, which enhances both humoral and cell-mediated immunity to oligopeptides in experimental animal models." ;
  rdfs:subClassOf obo:VO_0001359 .

obo:VO_0015797 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 25" ;
  rdfs:subClassOf obo:VO_0015492 .

obo:VO_0004755 a rdfs:Class ;
  rdfs:label "rSPV/H3-2A-H1 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0001913 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.26)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002345 .

obo:VO_0000766 a rdfs:Class ;
  rdfs:label "Pseudomonas vaccine" ;
  rdfs:comment "Vaccine that protects against Pseudomonas infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0003751 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0001817 , obo:VO_0010431 .

obo:VO_0019783 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003638 .

obo:VO_0018142 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0018135 .

obo:VO_0015093 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015087 , obo:VO_0015248 .

obo:VO_0002544 a rdfs:Class ;
  rdfs:label "Reticuloendotheliosis virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Reticuloendotheliosis virus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0000426 a rdfs:Class ;
  rdfs:label "period of persistence of vaccine induced immune response" ;
  rdfs:comment "period of persistence of vaccine induced immune response is a temporal interval during which a vaccine-induced immune response continuously exists. This term is related to the process 'persistence of vaccine induced immune response'." ;
  rdfs:subClassOf obo:BFO_0000038 .

obo:VO_0018861 a rdfs:Class ;
  rdfs:label "influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0002819 a rdfs:Class ;
  rdfs:label "Brucella abortus pgm mutant vaccine" ;
  rdfs:comment "A pgm mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus" ;
  rdfs:subClassOf obo:VO_0001134 .

obo:VO_0019870 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0005147 a rdfs:Class ;
  rdfs:label "SARS NDV-BC/S vaccine" ;
  rdfs:comment "A SARS-CoV recombinant vector vaccine that is made from the Newcastle disease virus from the mesogenic Beaudette C strainexpressing SARS-CoV S protein." ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0011534 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum DNA vaccine encoding TC0512" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012176 .

obo:VO_0020372 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Oral Capsule" ;
  rdfs:subClassOf obo:VO_0003449 .

obo:VO_0015047 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 6 Vaccine 0.06 MG/ML" ;
  rdfs:subClassOf obo:VO_0003300 .

obo:VO_0015584 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015542 , obo:VO_0015598 .

obo:VO_0006049 a rdfs:Class ;
  rdfs:label "rheumatic fever vaccine" ;
  rdfs:comment "Vaccine that protects against group A Streptococcus infection causing rheumatic fever." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000455 , obo:VO_0000772 .

obo:VO_0001622 a rdfs:Class ;
  rdfs:label "Bronchitis Mass & Conn Types, Live Virus Vaccine (USDA: 1231.1G)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0001178 a rdfs:Class ;
  rdfs:label "live attenuated influenza vaccine" ;
  rdfs:comment "live attenuated influenza vaccine is a live attenuated vaccine that protects against influenza viral infection." ;
  rdfs:subClassOf obo:VO_0000642 , obo:VO_0001220 .

obo:VO_0019889 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0002444 a rdfs:Class ;
  rdfs:label "fowlpox-Mareks Disease vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000985 , obo:VO_0001468 , obo:VO_0012162 .

obo:VO_0000392 a rdfs:Class ;
  rdfs:label "Campylobacter fetus vaccine" ;
  rdfs:comment "a Campylobacter bacterial vaccine that is used to protect against Campylobacter fetus infection" ;
  rdfs:subClassOf obo:VO_0000568 .

obo:OBI_0000968 a rdfs:Class ;
  rdfs:label "device" ;
  rdfs:comment "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent."@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OPL_0000292 a rdfs:Class ;
  rdfs:label "Plasmodium merozoite stage" ;
  rdfs:comment "A merozoite stage in the Plasmodium lifecycle that occurs in the bloodstream or hepatocytes of a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000036 .

obo:VO_0007056 a rdfs:Class ;
  rdfs:label "WT1 124-138 peptide vaccine" ;
  rdfs:comment "A synthetic peptide vaccine consisting of a HLA-DR15-restricted human Wilms' Tumor protein-1 (WT1) peptide comprised of amino acids 124 through 138, a HLA class II-restricted WT1 peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 124-138 peptide may stimulate a CD4-positive helper T-lymphocyte-mediated immune response against WT1 expressing cells. Activated helper T-cells stimulate dendritic cells, and activate the proliferation of other T-lymphoctes and B-lymphocytes. This causes tumor cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing tumor cells. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0005486 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0004644 a rdfs:Class ;
  rdfs:label "CAdVax-Filoviruses (Ebola ) vaccine" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0010912 a rdfs:Class ;
  rdfs:label "NP" ;
  rdfs:comment "Guinea pigs infected with a single intranasal inoculation of HPIV3/EboGP-NP showed no apparent signs of disease yet developed a strong humoral response specific to the EV proteins. When these animals were challenged with an intraperitoneal injection of 10(3) PFU of EV, there were no outward signs of disease, no viremia or detectable EV antigen in the blood, and no evidence of infection in the spleen, liver, and lungs. In contrast, all of the control animals died or developed severe EV disease following challenge [PubMed: 16474134]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0010488 a rdfs:Class ;
  rdfs:label "licensed human Leishmania vaccine" ;
  rdfs:comment "Leishmania vaccine is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000762 .

obo:VO_0019209 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019714 .

obo:VO_0003984 a rdfs:Class ;
  rdfs:label "Adacel Injectable Product" ;
  rdfs:subClassOf obo:VO_0000005 .

obo:VO_0015262 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0015261 .

obo:VO_0021014 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution [Varilrix]" ;
  rdfs:subClassOf obo:VO_0021012 , obo:VO_0021013 , obo:VO_0021041 .

obo:VO_0019548 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003733 , obo:VO_0019544 .

obo:VO_0017755 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0017803 .

obo:VO_0020074 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0019907 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluvirin 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020477 .

obo:VO_0007241 a rdfs:Class ;
  rdfs:label "ALVAC-B7-CEA vaccine" ;
  rdfs:comment "A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus. ALVAC-B7-CEA expresses carcinoembryonic antigen (CEA), a protein that is overexpressed by many tumor cells, and B7.1 (also known as CD80), the natural ligand for the T-cell antigen CD28, to augment the host immune response. This agent has been shown to stimulate a host immune response against tumor cells that express CEA. (NCI04)" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:DOID_13258 a rdfs:Class ;
  rdfs:label "typhoid fever"@en ;
  rdfs:comment "A primary bacterial infectious disease that is a communicable systemic illness, has_material_basis_in Salmonella enterica subsp enterica serovar Typhi, which is transmitted_by ingestion of food or water contaminated with the feces of an infected person. The infection has_symptom fever, has_symptom diarrhea, has_symptom prostration, has_symptom headache, has_symptom splenomegaly, has_symptom liver enlargement, has_symptom eruption of rose-colored spots, and has_symptom leukopenia."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:VO_0017646 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [Tetabulin]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0007561 a rdfs:Class ;
  rdfs:label "Fowlpox-PSA-TRICOM Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant fowlpox virus encoding human prostate-specific antigen (PSA) and TRICOM, a combination of three immunostimulants (i.e., B7.1, ICAM-1, and LFA-3). Administration of this agent may induce a cytotoxic T cell response against PSA-expressing tumor cells. Dendritic cells infected with TRICOM vectors greatly enhance naive T-cell activation and peptide-specific T-cell stimulation. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0016772 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0016719 .

obo:VO_0000148 a rdfs:Class ;
  rdfs:label "antibody role" ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:NCBITaxon_476 a rdfs:Class ;
  rdfs:label "Moraxella bovis" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:VO_0001208 a rdfs:Class ;
  rdfs:label "Brucella abortus BLS-L7/L12 vaccine" ;
  rdfs:comment "B. abortus BLS-L7/L12 is a B. abortus subunit vaccine using L7/L12 that is made as a recombinant BLS-L7/L12 fusion protein vaccine." ;
  rdfs:subClassOf obo:VO_0000323 .

obo:VO_0007211 a rdfs:Class ;
  rdfs:label "AdRTVP-1-Transduced Prostate Cancer Cell-Based Vaccine" ;
  rdfs:comment "A cell-based vaccine comprised of prostate cancer cells transduced with an adenoviral vector encoding human RTVP-1 (AdRTVP-1), with potential antineoplastic and immunostimulating activities. RTVP-1, also referred to as glioma pathogenesis-related protein 1 (GLIP1), is down-regulated in prostate tumors. Regulated by tumor suppressor p53, the expression of RTVP-1 functions as a tumor suppressor, and is abundant in normal human prostate epithelial cells as well as in differentiated macrophages. Administration of this vaccine leads to an induction of apoptosis through the expression of RTVP-1 and results in a reduction in cellular proliferation in prostate cancer cells. In addition, this cancer-cell based vaccine may induce a cytotoxic T lymphocyte (CTL) response against prostate specific tumor associated antigens, resulting in an immune-mediated prostate cancer cell death. Furthermore, RTVP-1 stimulates CTL and natural killer (NK) cell activities." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0001502 a rdfs:Class ;
  rdfs:label "Infectious Bronchitis Virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Infectious Bronchitis Virus (IBV) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0004897 .

obo:VO_0007621 a rdfs:Class ;
  rdfs:label "IL-12p70 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0004222 a rdfs:Class ;
  rdfs:label "Inactivated PMV-3 vaccine with Specol" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0001527 .

obo:VO_0015223 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015218 .

obo:VO_0017544 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003407 .

obo:VO_0010290 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0015977 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1" ;
  rdfs:subClassOf obo:VO_0003264 .

obo:IAO_8000010 a rdfs:Class ;
  rdfs:label "exclusion subset ontology module"@en ;
  rdfs:comment "A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:VO_0002800 a rdfs:Class ;
  rdfs:label "obsolete A. salmonicida live-attenuated vaccine encoding AroA" ;
  rdfs:comment "The aroA gene was inactivated by inserting a fragment expressing kanamycin resistance within the coding sequence and challenged in fish. The LD50 for unvaccinated fish was 71. In contrast, the LD50 was 1.8 x 104 in fish vaccinated once and 3 x 105 in fish vaccinated twice" .

obo:OPL_0000414 a rdfs:Class ;
  rdfs:label "Primates erythrocyte" ;
  rdfs:comment "An erythrocyte that is a part of or originated from a primate." ;
  rdfs:subClassOf obo:CL_0000232 , obo:OPL_0000311 .

obo:VO_0010215 a rdfs:Class ;
  rdfs:label "Respiratory syncytial virus (RSV) vaccine, unspecified" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000753 .

obo:VO_0003935 a rdfs:Class ;
  rdfs:label "GARDASIL 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003934 .

obo:VO_0007632 a rdfs:Class ;
  rdfs:label "Large Multivalent Immunogen (LMI) vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0003019 a rdfs:Class ;
  rdfs:label "intradermal vaccination" ;
  rdfs:comment "vaccination process that occurs in intradermal route." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0004093 a rdfs:Class ;
  rdfs:label "NYVAC vaccine" ;
  rdfs:subClassOf obo:VO_0000651 .

obo:VO_0019146 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0003866 a rdfs:Class ;
  rdfs:label "1 ML RabAvert 2.5 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003864 .

obo:VO_0003999 a rdfs:Class ;
  rdfs:label "BOOSTRIX vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003998 .

obo:VO_0021119 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0001055 a rdfs:Class ;
  rdfs:label "chimpanzee adenovirus vaccine vector" ;
  rdfs:comment "an adenovirus vaccine vector that uses a chimpanzee adenovirus strain" ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0011316 a rdfs:Class ;
  rdfs:label "M protein" ;
  rdfs:comment "A recombinant vaccinia virus that expressed the M protein of Dengue 4 virus was constructed. Mice immunized with the recombinant virus were protected against subsequent dengue 4 encephalitis challenge [PubMed: 1926792]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010844 .

obo:VO_0002826 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei asd mutant vaccine" ;
  rdfs:comment "An asd mutant is highly attenuated in mice. This mutant was also able to protect against acute inhalation melioidosis caused by challenge with wild type B. pseudomallei" ;
  rdfs:subClassOf obo:VO_0012175 .

obo:VO_0011270 a rdfs:Class ;
  rdfs:label "CtxB" ;
  rdfs:comment "The immune sera elicited by CTB DNA vaccine were functional and protective against V. cholerae O1 infection in mice [PubMed: 19443090]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010848 .

obo:VO_0011449 a rdfs:Class ;
  rdfs:label "Eimeria tenella DNA vaccine pcDNA-TA4-IL-2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001137 .

obo:VO_0016050 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 3" ;
  rdfs:subClassOf obo:VO_0015670 , obo:VO_0015805 .

obo:VO_0004782 a rdfs:Class ;
  rdfs:label "rAdV-SjTPI.opt vaccine" ;
  rdfs:subClassOf obo:VO_0001229 .

obo:VO_0010889 a rdfs:Class ;
  rdfs:label "TC0768 hypothetical protein" ;
  rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0767/768 showed significant levels of protection when compared to negative control animals [PubMed: 17239501]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010795 .

obo:VO_0000871 a rdfs:Class ;
  rdfs:label "Purevax Feline Rabies vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0000652 .

obo:VO_0007028 a rdfs:Class ;
  rdfs:label "NY-ESO-B vaccine" ;
  rdfs:comment "A tumor-associated antigen belonging to the family of immunogenic testicular proteins that are aberrantly expressed in human cancers in a lineage-nonspecific fashion. Reverse transcription-PCR analysis showed NY-ESO-1 mRNA expression in a variable proportion of a wide array of human cancers, including melanoma, breast cancer, bladder cancer, prostate cancer, and hepatocellular carcinoma; and restricted expression in normal tissues, with high-level mRNA expression found only in testis and ovary tissues. The gene for NY-ESO-1 maps to Xq28 and codes for an 18-kDa protein having no homology with any known protein. NY-ESO-1 elicits a strong, integrated humoral and cellular immune response in a high proportion of patients with NY-ESO-1-expressing tumors and is under investigation as a cancer immunotherapy agent." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000422 , obo:VO_0005425 , obo:VO_0005429 , obo:VO_0005484 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0016721 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016705 , obo:VO_0016706 .

obo:VO_0012376 a rdfs:Class ;
  rdfs:label "HtrA" ;
  rdfs:comment "rHtrA was found to be very immunogenic and partially protective in both the passive infant rat model of bacteremia and the active chinchilla model of otitis media [PubMed: 9488373]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:VO_0001461 a rdfs:Class ;
  rdfs:label "bird vaccine" ;
  rdfs:comment "Vaccine that used for immunizing birds." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001218 .

obo:VO_0001655 a rdfs:Class ;
  rdfs:label "Bursal Disease Standard & Variant, Killed Virus Vaccine (USDA: 12B5.4A)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000960 , obo:VO_0007748 .

obo:VO_0002723 a rdfs:Class ;
  rdfs:label "TK from Herpes simplex virus type 1 and 2" ;
  rdfs:comment "A thymidine kinase-deficient (TK) mutant was found to be attenuated in mice. This mutant induced complete protection from challenge with wild type HSV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001437 .

obo:VO_0003553 a rdfs:Class ;
  rdfs:label "Spirochaetia vaccine" ;
  rdfs:comment "Vaccine that protects against Spirochaetia infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0017515 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 100" ;
  rdfs:subClassOf obo:VO_0017506 .

obo:VO_0007364 a rdfs:Class ;
  rdfs:label "Bcr-Abl (b3a2)-derived peptide vaccine" ;
  rdfs:comment "A cancer vaccine consisting of the bcr-abl b2a2 fusion oncoprotein, frequently expressed in chronic myelogenous leukemia (CML), with potential antineoplastic activity. Vaccination with the bcr-abl (b2a2)-derived peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express the bcr-abl b2a2 fusion protein. The vaccine is made from made from the proteins that cause leukemia cells in CML to behave abnormally. Imatinib mesylate is the standard therapy for CML and blocks the function of this protein. In combination, these may decrease or eliminate all evidence of disease in patients who have CML that is in remission after treatment with imatinib mesylate, but who still have small amounts of detectable disease.  " ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0002574 a rdfs:Class ;
  rdfs:label "znuA from Brucella spp." ;
  rdfs:comment "Deletion of gene znuA attenuates Brucella abortus and this live attenuated vaccine was challenged in mice. These mice showed significantly fewer spenic CFU" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000793 .

obo:VO_0016346 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:VO_0019422 a rdfs:Class ;
  rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.08 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 12 UNT/ML [Certiva]" ;
  rdfs:subClassOf obo:VO_0001214 , obo:VO_0003122 .

obo:VO_0003547 a rdfs:Class ;
  rdfs:label "Enterovirus vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Enterovirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0000937 a rdfs:Class ;
  rdfs:label "sucrose albumin cell culture residual in vaccine" ;
  rdfs:comment "a cell culture residual in vaccine that is sucrose albumin." ;
  rdfs:subClassOf obo:VO_0000856 .

obo:VO_0019947 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Flulaval 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020339 .

obo:VO_0019824 a rdfs:Class ;
  rdfs:label "influenza A virus A/North Carolina/04/2016 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020331 .

obo:VO_0010289 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0017606 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 2" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0016321 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015934 .

obo:VO_0018786 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0016653 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:NCBITaxon_59201 a rdfs:Class ;
  rdfs:label "Salmonella enterica subsp. enterica" ;
  rdfs:subClassOf obo:NCBITaxon_590 .

obo:VO_0007575 a rdfs:Class ;
  rdfs:label "ALVAC-CEA (6D)-B7.1 vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0010106 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii MIC4" ;
  rdfs:comment "A MIC4 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0000810 a rdfs:Class ;
  rdfs:label "pSCAR DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pSCAR . CMV promotor is used." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001832 a rdfs:Class ;
  rdfs:label "Mink Distemper-Enteritis Modified Live & Killed Virus Vaccine (USDA: 1679.31)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0002484 , obo:VO_0007748 , obo:VO_0010475 .

obo:VO_0011539 a rdfs:Class ;
  rdfs:label "Leishmania donovani ORFF protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0001142 .

obo:VO_0016471 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0000208 a rdfs:Class ;
  rdfs:label "vaccine in research role" ;
  rdfs:comment "A vaccine role that is not licensed or in clinical trial; instead, it has been experimently approved to induce protection or treatment effect in vivo in at least an experimental animal model. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0020115 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML [Attenuvax]" ;
  rdfs:subClassOf obo:VO_0000007 , obo:VO_0015053 .

obo:VO_0000112 a rdfs:Class ;
  rdfs:label "Tripedia vaccine" ;
  rdfs:comment "Product Name: Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000738 , obo:VO_0001217 .

obo:VO_0019113 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.09 MG/ML Prefilled Syringe [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0005024 a rdfs:Class ;
  rdfs:label "pCMV-TPA/ZS7 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCMV-TPA/ZS7.  This plasmid contains a CMV promoter and is generated from pCMV-ZS7 by attaching hTPA to ospC ZS7." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001382 a rdfs:Class ;
  rdfs:label "rabbit hemorrhagic disease virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Rabbit hemorrhagic disease virus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0017379 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Td Impfstoff]" ;
  rdfs:subClassOf obo:VO_0018786 .

obo:VO_0016916 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017297 .

obo:VO_0020837 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Afluria]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0000671 a rdfs:Class ;
  rdfs:label "Salmonella typhi vaccine" ;
  rdfs:comment "A Salmonella vaccine against typhoid fever (or called typoid), caused by Salmonella enterica enterica, serovar Typhi. " ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000768 .

obo:VO_0003680 a rdfs:Class ;
  rdfs:label "Fluvirin 2015-2016 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003679 .

obo:VO_0006009 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine adult dosage" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 .

obo:VO_0003944 a rdfs:Class ;
  rdfs:label "Cervarix Injectable Product" ;
  rdfs:subClassOf obo:VO_0011559 .

obo:VO_0010972 a rdfs:Class ;
  rdfs:label "Omp19" ;
  rdfs:comment "Brucella Omp19 is a protective antigen [PubMed: 18981242]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0001564 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0000987 , obo:VO_0001220 .

obo:VO_0000451 a rdfs:Class ;
  rdfs:label "Parainfluenza 3 virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Parainfluenza 3 virus." ;
  rdfs:subClassOf obo:VO_0000749 .

obo:VO_0019835 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus antigen 0.03 MG/ML [Afluria 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003734 .

obo:VO_0020978 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, Inactivated, Strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain A / South Australia / 55/2014 Type Wild" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0010303 , obo:VO_0010415 .

obo:VO_0002189 a rdfs:Class ;
  rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.23)" .

obo:VO_0000035 a rdfs:Class ;
  rdfs:label "Dryvax vaccine" ;
  rdfs:comment "A vaccinia virus vaccine that is a freeze-dried calf lymph smallpox vaccine, specifically, Dryvax is a live-virus preparation of vaccinia prepared from calf lymph. " ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000433 , obo:VO_0000455 , obo:VO_0010452 .

obo:VO_0005259 a rdfs:Class ;
  rdfs:label "COVID-19 rNDV vector vaccine by Laboratorio Avi-Mex" ;
  rdfs:comment "A recombinant Newcastle Disease Virus vectored vaccine for SARS-CoV-2 by Laboratorio Avi-Mex" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0010040 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum ABRA" ;
  rdfs:comment "A ABRA protein that is part of Plasmodium falciparum|An ABRA protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0000424 a rdfs:Class ;
  rdfs:label "polyvalent pneumococcal vaccine" ;
  rdfs:comment "a pneumococcal vaccine that is formed using polyvalent polysaccharides" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010453 .

obo:VO_0016143 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0007155 a rdfs:Class ;
  rdfs:label "PSA:154-163 Peptide vaccine" ;
  rdfs:comment "A synthetic peptide based on sequence corresponding to positions 154-163 of the amino acids of prostate-specific antigen (PSA), VISNDVCAQV. Upon administration, PSA:154-163 peptide vaccine may elicit a cytotoxic T-cell response against tumor cells that express PSA." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0019269 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010431 .

obo:VO_0015034 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 11 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 16 Vaccine 0.12 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 31 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 33 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 45 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 52 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 58 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 6 Vaccine 0.06 MG/ML Injection [Gardasil 9]" ;
  rdfs:subClassOf obo:VO_0015037 .

obo:VO_0016241 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015910 .

obo:VO_0002477 a rdfs:Class ;
  rdfs:label "Swine Influenza vaccine" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0001474 .

obo:VO_0000162 a rdfs:Class ;
  rdfs:label "vaccine organism avirulent" ;
  rdfs:comment "a virulence of vaccine organism that shows an avirulent pheontype of the organism as the major component of a vaccine. The avirulence means that an vaccine organism is not virulent and does not cause pathogenic phenotype in a host organism." ;
  rdfs:subClassOf obo:PATO_0002146 .

obo:VO_0017350 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Acel Imune]" ;
  rdfs:subClassOf obo:VO_0017349 .

obo:VO_0001923 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002353 .

obo:VO_0019809 a rdfs:Class ;
  rdfs:label "influenza A virus A/Idaho/07/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Indiana/08/2018 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020332 .

obo:VO_0004096 a rdfs:Class ;
  rdfs:label "Smallpox DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000651 .

obo:VO_0015932 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 20" ;
  rdfs:subClassOf obo:VO_0015635 , obo:VO_0016037 .

obo:OGG_3000887681 a rdfs:Class ;
  rdfs:label "trpD" ;
  rdfs:comment "Probable anthranilate phosphoribosyltransferase TrpD" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0002560 a rdfs:Class ;
  rdfs:label "asp24 from B. abortus" ;
  rdfs:comment "A asp24 mutation in Brucella abortus is attenuated and provides significant protection in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000793 .

obo:VO_0015251 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML [Havpur]" ;
  rdfs:subClassOf obo:VO_0015249 .

obo:VO_0019545 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003715 , obo:VO_0010427 , obo:VO_0019544 .

obo:VO_0002930 a rdfs:Class ;
  rdfs:label "obsolete Shigella sonnei virG/senA/senB mutant vaccine" ;
  rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" .

obo:VO_0004044 a rdfs:Class ;
  rdfs:label "Leishmania major PSA-2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001231 .

obo:VO_0020434 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Waymade" .

obo:NCBITaxon_10359 a rdfs:Class ;
  rdfs:label "Human betaherpesvirus 5" ;
  rdfs:subClassOf obo:NCBITaxon_10358 .

obo:VO_0016255 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015918 .

obo:VO_0010210 a rdfs:Class ;
  rdfs:label "pneumococcal conjugate vaccine, 7 valent" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000424 .

obo:VO_0016642 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0016622 .

obo:VO_0018012 a rdfs:Class ;
  rdfs:label "poliomyelitis virus type 1 brunhilde / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018047 .

obo:VO_0020806 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0019465 .

obo:VO_0016374 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015941 .

obo:VO_0018045 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 3 (Saukett) 600000 CELLS/ML" ;
  rdfs:subClassOf obo:VO_0003837 .

obo:VO_0005153 a rdfs:Class ;
  rdfs:label "AdCOVID vaccine" ;
  rdfs:comment "A SARS-CoV-2 single dose intranasal vaccine manufactured by Altimmune in collaboration with the University of Alabama-Birmingham. This vaccine was discontinued after a Phase 1 trial." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005268 .

obo:VO_0003186 a rdfs:Class ;
  rdfs:label "Hepatitis B vaccine foreign to USA" ;
  rdfs:comment "A Hepatitis B vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0003444 , obo:VO_0010439 .

obo:VO_0010130 a rdfs:Class ;
  rdfs:label "host sex variable" ;
  rdfs:comment "A variable representing the biological sex of the host" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0019112 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0005482 a rdfs:Class ;
  rdfs:label "SLA-AF vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant is an oil-in-water emulsion that induces Th1-based immune response." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0010021 a rdfs:Class ;
  rdfs:label "Leishmania  donovani P1" ;
  rdfs:comment "A P1 protein that is part of Leishmania  donovani" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0015062 a rdfs:Class ;
  rdfs:label "injectable product" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:VO_0015178 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015177 .

obo:VO_0001369 a rdfs:Class ;
  rdfs:label "H2O2-killed vaccine" ;
  rdfs:comment "an inactivation vaccine that is prepared by H2O2 inactivation." ;
  rdfs:subClassOf obo:VO_0000017 .

obo:VO_0002759 a rdfs:Class ;
  rdfs:label "py36 from Plasmodium yoelii" ;
  rdfs:comment "A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001452 .

obo:VO_0006046 a rdfs:Class ;
  rdfs:label "rabies vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010448 .

obo:VO_0011224 a rdfs:Class ;
  rdfs:label "AMA-1 from P. berghei" ;
  rdfs:comment "Mice immunized with recombinant PbAMA-1 were partially protected from the challenge of P. berghei [PubMed: 17639690]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015475 .

obo:VO_0001885 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Killed Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin (USDA: 4265.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002337 .

obo:VO_0004103 a rdfs:Class ;
  rdfs:label "Truncated Recombinant DoBV Nucleocapsid Proteins (Dob-N rNp) vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012167 .

obo:VO_0011375 a rdfs:Class ;
  rdfs:label "Babesia bovis GST-12D3 vaccine" ;
  rdfs:subClassOf obo:VO_0000925 .

obo:UBERON_0000004 a rdfs:Class ;
  rdfs:label "nose" ;
  rdfs:comment "The olfactory organ of vertebrates, consisting of nares, olfactory epithelia and the structures and skeletal framework of the nasal cavity." ;
  rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0004121 .

obo:VO_0020502 a rdfs:Class ;
  rdfs:label "influenza B virus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0003615 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2014-2015 Formula 0.1 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003614 .

obo:VO_0020364 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Oral Capsule [Vivotif Berna]" ;
  rdfs:subClassOf obo:VO_0020372 .

obo:VO_0017841 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide Injection [AC Vax]" ;
  rdfs:subClassOf obo:VO_0017893 .

obo:VO_0016437 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0016504 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:VO_0018593 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0018768 .

obo:NCBITaxon_5850 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi" ;
  rdfs:subClassOf obo:NCBITaxon_418103 .

obo:VO_0011411 a rdfs:Class ;
  rdfs:label "Hepatitis B virus DNA vaccine encoding HBVgp2 pre-S1/pre-S2/S" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000644 .

obo:VO_0003265 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0015020 .

obo:VO_0004689 a rdfs:Class ;
  rdfs:label "M.S-Delta-esx-3-IKEPLUS Mycobacterium tuberculosis vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0018260 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML [VACCIN RABIQUE INACTIVE MERIEUX]" ;
  rdfs:subClassOf obo:VO_0003858 .

obo:OPL_0000254 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum salivary gland-derived sporozoite stage" ;
  rdfs:comment "A salivary gland-derived sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the human host." ;
  rdfs:subClassOf obo:OPL_0000115 , obo:OPL_0000253 , obo:OPL_0000302 .

obo:VO_0000248 a rdfs:Class ;
  rdfs:label "history of asthma" ;
  rdfs:subClassOf obo:VO_0000207 .

obo:VO_0017617 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017616 , obo:VO_0017626 .

obo:VO_0017657 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0000210 a rdfs:Class ;
  rdfs:label "hemagglutination-inhibition assay" ;
  rdfs:comment "an immune response detection assay that detects specific antiviral antibodies in a test serum. The serum, usually a twofold dilution series, is mixed with a standard number, usually 4 to 8 HA units, of virus and incubated prior to the addition of a standard suspension of erythrocytes. The highest dilution of serum that inhibits hemagglutination is the HI titer of the serum. For example, influenza (AI) viruses agglutinate erythrocytes through the interaction of the virus surface glycoprotein, the hemagglutinin (HA), with receptors on the surface of the erythrocyte. Inhibition of the agglutination reaction by HA subtype-specific antisera is the basis of the hemagglutination-inhibition (HI) assay." ;
  rdfs:subClassOf obo:VO_0000584 .

obo:VO_0021036 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0021035 , obo:VO_0021038 .

obo:VO_0010753 a rdfs:Class ;
  rdfs:label "G- bacterium protein" ;
  rdfs:subClassOf obo:VO_0010751 .

obo:VO_0004594 a rdfs:Class ;
  rdfs:label "Plasmodium berghei DNA vaccine CSP-3p28" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002513 .

obo:VO_0019216 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019728 .

obo:VO_0001726 a rdfs:Class ;
  rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.05)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000620 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0020284 a rdfs:Class ;
  rdfs:label "varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML Injection [Shingrix]" ;
  rdfs:subClassOf obo:VO_0020282 , obo:VO_0020283 .

obo:VO_0016179 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0004288 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis mce-3 mutant vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0019433 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.036 MG/ML / Haemophilus capsular oligosaccharide 0.05 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0019425 .

obo:VO_0004298 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pIRES/HA/GM-CSF encoding HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0004239 a rdfs:Class ;
  rdfs:label "HBsAg liposomal MTP-PE vaccine" ;
  rdfs:subClassOf obo:VO_0000644 .

obo:VO_0005090 a rdfs:Class ;
  rdfs:label "IIBR-100 vaccine" ;
  rdfs:comment "A rVSV-SARS-CoV-2-S vaccine developed by the Israel Institute for Biological Research (IIBR)." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0002403 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ;
  rdfs:subClassOf obo:VO_0002404 .

obo:DOID_1324 a rdfs:Class ;
  rdfs:label "lung cancer"@en ;
  rdfs:comment "A respiratory system cancer that is located_in the lung."@en ;
  rdfs:subClassOf obo:DOID_0050615 , obo:DOID_850 .

obo:VO_0007520 a rdfs:Class ;
  rdfs:label "dendritic vaccine, autologous hematopoietic stem cells, cytotoxic lymphocytes" ;
  rdfs:comment "A cancer vaccine from tumor cells and tumor stem cells that are isolated from a sample from a patient with glioblastoma multiforme. Dendritic cells are isolated from peripheral blood mononuclear cells and cultured. The tumor sample provides tumor specific antigens to prepare the dendritic vaccine. Cytotoxic lymphocytes are obtained from peripheral blood after dendritic vaccine administrations. Hematopoietic stem cells are harvested from closely related donor after granulocyte-colony-stimulating factor (G-CSF) administration. Autologous haploidentical hematopoietic stem cells are administered intrathecally, dendritic cells are administered subcutaneously, and cytotoxic lymphocytes are adminstered intrathecally. The combination of these treatments may control tumor cell quantity and target regulation of effector functions of tumor stem cells." ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0017368 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000943 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0003136 a rdfs:Class ;
  rdfs:label "YF 17DD-YFV vaccine" ;
  rdfs:comment "A YF-17DD vaccine t hat is manufactured by Bio-Manguinhos" ;
  rdfs:subClassOf obo:VO_0003135 .

obo:VO_0002023 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 45B5.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002378 .

obo:VO_0004135 a rdfs:Class ;
  rdfs:label "Chlamyvax FQ vaccine" ;
  rdfs:subClassOf obo:VO_0000463 .

obo:VO_0000773 a rdfs:Class ;
  rdfs:label "MSP3-LSP subunit vaccine with aluminium hydroxide adjuvant" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:OPL_0000167 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum macrogamete" ;
  rdfs:comment "A Plasmodium falciparum gamete that is a matured form of the macrogametocyte and is found in the midgut of a mosquito vector. The macrogamete is fertilized by the microgamete, forming the zygote" ;
  rdfs:subClassOf obo:OPL_0000258 , obo:OPL_0000265 .

obo:VO_0010253 a rdfs:Class ;
  rdfs:label "vaccination frequency variable" ;
  rdfs:comment "A variable represting the number of occurences a vaccination was administered" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0016583 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Ambirix]" ;
  rdfs:subClassOf obo:VO_0016560 .

obo:VO_0002426 a rdfs:Class ;
  rdfs:label "Canine Distemper-Hepatitis-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0002415 , obo:VO_0012180 .

obo:VO_0004774 a rdfs:Class ;
  rdfs:label "NYVAC-HIV-1 vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0003026 a rdfs:Class ;
  rdfs:label "vaccine stabilizer role" ;
  rdfs:comment "a role inheres in vaccine component when added into vaccine's formulation, it tends to inhibit the reaction between two or more other vaccine substances in the final vaccine formulation; it also helps to protect the vaccine from adverse conditions such as the freeze-drying process or heat." ;
  rdfs:subClassOf obo:VO_0000415 .

obo:VO_0000563 a rdfs:Class ;
  rdfs:label "bacterial and viral combination vaccine" ;
  rdfs:comment "a combination vaccine that is used against both bacterial and viral infections." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 , obo:VO_0000609 , obo:VO_0000641 .

obo:VO_0020621 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0020617 .

obo:VO_0020943 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus antigen Nasal Spray [Flumist]" ;
  rdfs:subClassOf obo:VO_0020941 .

obo:DOID_3369 a rdfs:Class ;
  rdfs:label "Ewing sarcoma"@en ;
  rdfs:comment "A connective tissue cancer that has_material_basis_in neural crest cells derives_from undeveloped, undifferentiated neuroectoderm."@en ;
  rdfs:subClassOf obo:DOID_201 .

obo:VO_0004367 a rdfs:Class ;
  rdfs:label "Herpes simplex virus DNA vaccine ICP-27 DNA encoding ICP-27" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:NCBITaxon_1783272 a rdfs:Class ;
  rdfs:label "Bacillati" ;
  rdfs:subClassOf obo:NCBITaxon_2 .

obo:VO_0020620 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0020617 .

obo:VO_0003255 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 5 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0001821 a rdfs:Class ;
  rdfs:label "Escherichia coli avirulent live culture vaccine (USDA: 1551.02)" ;
  rdfs:subClassOf obo:VO_0000125 , obo:VO_0000455 , obo:VO_0000962 , obo:VO_0007748 .

obo:VO_0000543 a rdfs:Class ;
  rdfs:label "attenuated Mycobacterium bovis strain WAg539 vaccine" ;
  rdfs:subClassOf obo:VO_0000077 , obo:VO_0001217 .

obo:VO_0006061 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 3 mcg/0.2mL dose tris-sucrose formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0017736 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / Haemophilus B Conjugate Vaccine / Hepatitis B Surface Antigen Vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010445 , obo:VO_0017805 , obo:VO_0020832 .

obo:VO_0019152 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0010792 a rdfs:Class ;
  rdfs:label "Varicella-zoster virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:DOID_1398 a rdfs:Class ;
  rdfs:label "parasitic infectious disease"@en ;
  rdfs:comment "A disease by infectious agent that is carried out by a parasite which by definition is a pathogen that simultaneously injures and derives sustenance from its host."@en ;
  rdfs:subClassOf obo:DOID_0050117 .

obo:VO_0020862 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Csl] Box of 10" ;
  rdfs:subClassOf obo:VO_0020861 , obo:VO_0020884 .

obo:VO_0016933 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017395 .

obo:VO_0020669 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension [Bcg Medac]" ;
  rdfs:subClassOf obo:VO_0020750 .

obo:VO_0002712 a rdfs:Class ;
  rdfs:label "3b from Feline infectious peritonitis virus" ;
  rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001434 .

obo:VO_0004655 a rdfs:Class ;
  rdfs:label "BacMam-sHAPQ vaccine" ;
  rdfs:subClassOf obo:VO_0001211 .

obo:VO_0004261 a rdfs:Class ;
  rdfs:label "live TC-83 VEE vaccine with DHEA" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0001499 .

obo:VO_0003658 a rdfs:Class ;
  rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010303 , obo:VO_0010415 .

obo:OAE_0000001 a rdfs:Class ;
  rdfs:label "adverse event" ;
  rdfs:comment "a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event." ;
  rdfs:subClassOf obo:OGMS_0000061 .

obo:VO_0016230 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Gerke" ;
  rdfs:subClassOf obo:VO_0015906 .

obo:VO_0011417 a rdfs:Class ;
  rdfs:label "E. coli C3389 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0018034 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injectable Solution [Ipol]" ;
  rdfs:subClassOf obo:VO_0000054 , obo:VO_0018033 .

obo:VO_0011433 a rdfs:Class ;
  rdfs:label "prostate cancer DNA vaccine encoding prostatic acid phosphatase (PAP)" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0019689 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2016-2017 Formula]" ;
  rdfs:subClassOf obo:VO_0003744 .

obo:VO_0003888 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Flublok 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003886 .

obo:VO_0002275 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine-Mycoplasma Gallisepticum Bacterin (USDA: 48B5.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002454 , obo:VO_0007748 .

obo:VO_0010463 a rdfs:Class ;
  rdfs:label "humoral immune marker" ;
  rdfs:comment "An immune biomarker that indicates a humoral immune response." ;
  rdfs:subClassOf obo:OPMI_0000446 .

obo:VO_0015240 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015238 , obo:VO_0015242 .

obo:VO_0001773 a rdfs:Class ;
  rdfs:label "equine influenza killed virus vaccine (USDA: 1505.25)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0001176 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0011347 a rdfs:Class ;
  rdfs:label "obsolete rLm/iglC" .

obo:VO_0004993 a rdfs:Class ;
  rdfs:label "Ad35.CS.01 malaria vaccine" ;
  rdfs:comment "A P. falciparum malaria vaccine that is formed by tull length CS-expressing replication-deficient recombinant human adenovirus 35." ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0004427 a rdfs:Class ;
  rdfs:label "B-cell lymphoma DNA vaccine VCL-1642.XXX encoding a chimeric immunoglobulin molecule onsisting of tumor-specific variable (Id) regions" ;
  rdfs:comment "Gene name: Immunoglobulin" ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0017818 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017445 .

obo:NCBITaxon_11036 a rdfs:Class ;
  rdfs:label "Venezuelan equine encephalitis virus" ;
  rdfs:subClassOf obo:NCBITaxon_11019 .

obo:VO_0020568 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippeimpfstoff Ratiopharm] by Mylan" ;
  rdfs:subClassOf obo:VO_0020565 .

obo:VO_0000011 a rdfs:Class ;
  rdfs:label "vaccine B cell epitope" ;
  rdfs:subClassOf obo:VO_0000811 .

obo:VO_0007215 a rdfs:Class ;
  rdfs:label "AIM2(-1)/HT001(-1)/TAF1B(-1) Frameshift Peptide Vaccine" ;
  rdfs:comment "A cancer vaccine containing the three frame shift peptides (FSP) AIM2(-1), HT001(-1) and TAF1B(-1), with potential immunomodulating activity. Upon administration, the AIM2(-1)/HT001(-1)/TAF1B(-1) FSP vaccine may induce an immune response against microsatellite instability (MSI) colorectal cancer-associated antigens. Frame shift mutations of AIM2 (absent in melanoma 2, an interferon-inducible protein), HT001 (asteroid homolog 1 or ASTE1, with an unknown function) and TAF1B (TATA box-binding protein-associated RNA polymerase I B, a transcription factor) are seen in MSI-positive colorectal cancers and may be associated with malignant transformation, tumor progression and the presence of tumor-infiltrating lymphocytes. These FSPs all have one-base deletions." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0007650 a rdfs:Class ;
  rdfs:label "Pulmonary BCG immunotherapy for malignant melanoma vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020096 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0003504 .

obo:VO_0019794 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:NCBITaxon_211880 a rdfs:Class ;
  rdfs:label "Leptospira interrogans serovar Canicola" ;
  rdfs:subClassOf obo:NCBITaxon_173 .

obo:VO_0018863 a rdfs:Class ;
  rdfs:label "influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0003005 a rdfs:Class ;
  rdfs:label "Leishmania donovani cen1 mutant vaccine" ;
  rdfs:comment "A cen1 mutant is attenuated in mice and hamsters and induces significant protection from challenge with wild type L. donovani" ;
  rdfs:subClassOf obo:VO_0001142 .

obo:VO_0011241 a rdfs:Class ;
  rdfs:label "Hsp90" ;
  rdfs:comment "A monkey vaccination trial using a Plasmodium falciparum protein fraction containing antigens of 90-110 kDa is reported.   Three monkeys out of five resisted a heavy challenge dose of highly virulent parasites.  Hsp90 was found in the immunoprecipitates obtained with SERP antisera. Interestingly, the response to hsp90 correlated with protection, high antibody titres being found only in the protected monkeys [PubMed: 8303938]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0007199 a rdfs:Class ;
  rdfs:label "Adenoviral Vector Ad5-CEA(6D) Vaccine" ;
  rdfs:comment "A replication-defective, E1- and E2b-deleted oncolytic adenoviral serotype 5 (Ad5) encoding an epitope of human carcinoembryonic antigen (CEA) with potential antineoplastic activity. Adenoviral vector Ad5-CEA(6D) vaccine expresses a highly immunogenic analogue of CEA [CAP1-(6D)]. Upon administration, this vaccine may induce both humoral and cellular immune responses against tumor cells expressing the CEA antigen, thereby resulting in the immune-mediated inhibition of tumor cell proliferation and tumor cell death. CEA, a tumor-associated antigen, is overexpressed in various tumor cell types. Deletion of early genes E1 and E2b in Ad5 potentially circumvent pre-existing anti-adenovirus immunity and is capable of inducing strong immune responses." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0018896 a rdfs:Class ;
  rdfs:label "influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0001466 a rdfs:Class ;
  rdfs:label "cattle vaccine" ;
  rdfs:comment "Vaccine that used for immunizing cattle." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001218 .

obo:VO_0004179 a rdfs:Class ;
  rdfs:label "Leishmania donovani LD31 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001142 .

obo:VO_0016631 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0016563 , obo:VO_0016615 .

obo:VO_0003705 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003703 .

obo:VO_0001581 a rdfs:Class ;
  rdfs:label "Salmonella Choleraesuis Avirulent Live Culture Vaccine (USDA: 19A1.01)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000768 , obo:VO_0000813 , obo:VO_0001217 .

obo:VO_0016814 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Pediacel] Box of 20" ;
  rdfs:subClassOf obo:VO_0016731 , obo:VO_0016756 , obo:VO_0016829 .

obo:VO_0010163 a rdfs:Class ;
  rdfs:label "diphtheria, tetanus toxoids and acellular pertussis vaccine, Haemophilus influenzae type b conjugate, and poliovirus vaccine, inactivated (DTaP-Hib-IPV)" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0017852 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.5 MG" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010289 , obo:VO_0010444 .

obo:VO_0002786 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis panCD mutant vaccine" ;
  rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:NCBITaxon_1336 a rdfs:Class ;
  rdfs:label "Streptococcus equi" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:VO_0016266 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015923 .

obo:VO_0010344 a rdfs:Class ;
  rdfs:label "FLUAD QUADRIVALENT vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0004673 , obo:VO_0010415 .

obo:NCBITaxon_41678 a rdfs:Class ;
  rdfs:label "Turkey adenovirus 3" ;
  rdfs:subClassOf obo:NCBITaxon_10508 .

obo:VO_0010188 a rdfs:Class ;
  rdfs:label "influenza, adjuvanted, inactivated, trivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0010415 .

obo:VO_0001077 a rdfs:Class ;
  rdfs:label "Mycoplasma synoviae vaccine" ;
  rdfs:comment "a bacterial vaccine against Mycoplasma synoviae infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000604 .

obo:VO_0019928 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Prefilled Syringe [Fluvirin 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019923 , obo:VO_0020473 .

obo:VO_0003170 a rdfs:Class ;
  rdfs:label "Imovax ID vaccine" ;
  rdfs:comment "A vaccine used to develop immunity to rabies." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010448 .

obo:VO_0007414 a rdfs:Class ;
  rdfs:label "monoclonal antibody 3H1 anti-idiotype vaccine" ;
  rdfs:comment "A recombinant monoclonal antibody in which the heavy and light chain variable domains mimic a specific epitope of the tumor-associated protein carcinoembryonic antigen (CEA). This agent is used as a cancer vaccine against tumors that express CEA." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005486 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0018679 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004815 .

obo:VO_0018087 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution [Priorix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018086 .

obo:VO_0016910 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017291 .

obo:VO_0016385 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 3 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015946 .

obo:VO_0016493 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0020137 a rdfs:Class ;
  rdfs:label "mumps virus vaccine live, Jeryl Lynn strain 40000 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML Injectable Solution [Biavax II]" ;
  rdfs:subClassOf obo:VO_0020133 , obo:VO_0020136 .

obo:VO_0018704 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 TCID Injectable Suspension [RUDIVAX] Box of 1" ;
  rdfs:subClassOf obo:VO_0018703 , obo:VO_0018706 .

obo:VO_0001991 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002362 .

obo:VO_0017136 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 2" ;
  rdfs:subClassOf obo:VO_0017133 , obo:VO_0017146 , obo:VO_0017600 .

obo:VO_0016880 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016833 , obo:VO_0016841 .

obo:VO_0018365 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003342 .

obo:VO_0019534 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine Injectable Suspension [HB-VAX]" ;
  rdfs:subClassOf obo:VO_0003416 .

obo:VO_0001360 a rdfs:Class ;
  rdfs:label "IFN-gamma vaccine adjuvant" ;
  rdfs:comment "A cytokine vaccine adjuvant that includes IFN-gamma." ;
  rdfs:subClassOf obo:VO_0001353 .

obo:VO_0005493 a rdfs:Class ;
  rdfs:label "ovarian cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against ovarian cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0002414 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus-Rabies Vaccine" ;
  rdfs:subClassOf obo:VO_0000650 , obo:VO_0002413 .

obo:CL_0000219 a rdfs:Class ;
  rdfs:label "motile cell" ;
  rdfs:comment "A cell that moves by its own activities." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:VO_0021177 a rdfs:Class ;
  rdfs:label "0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0021175 .

obo:VO_0016205 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 50 by Mtk" ;
  rdfs:subClassOf obo:VO_0015903 .

obo:VO_0004937 a rdfs:Class ;
  rdfs:label "human age 7 to 11 months at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0001859 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0002436 , obo:VO_0007748 .

obo:VO_0019511 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated Injection [Vaqta]" ;
  rdfs:subClassOf obo:VO_0010745 , obo:VO_0019510 .

obo:VO_0016518 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0015865 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015613 , obo:VO_0015684 , obo:VO_0015993 .

obo:VO_0004785 a rdfs:Class ;
  rdfs:label "rS.C-APP-ApxI/ApxII vaccine" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0005229 a rdfs:Class ;
  rdfs:label "COVIran Barakat vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine by Shifa Pharmed" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0011292 a rdfs:Class ;
  rdfs:label "Gp46" ;
  rdfs:comment "cDNAs encoding L. m. amazonensis gp46 antigen were subcloned into the VR1012 plasmid, and susceptible BALB/c mice were immunised with two i.m. injections of 100 microg of plasmid DNA.  Mice were challenged by the injection of 4 x 10^6 L. m. mexicana parasites in the foot pad to evaluate protection. Measurement of lesion size indicated that mice immunised with VR012-GP46 were partially protected against infection [PubMed: 11713811]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010837 .

obo:VO_0018302 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 5" ;
  rdfs:subClassOf obo:VO_0018276 , obo:VO_0018311 .

obo:VO_0018111 a rdfs:Class ;
  rdfs:label "1 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution [Priorix] Box of 100" ;
  rdfs:subClassOf obo:VO_0018110 , obo:VO_0018114 , obo:VO_0018177 .

obo:VO_0018649 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine Injection [Cervarix]" ;
  rdfs:subClassOf obo:VO_0018648 , obo:VO_0018652 .

obo:VO_0020732 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Suspension [ImmuCyst] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020731 .

obo:VO_0000850 a rdfs:Class ;
  rdfs:label "vaccine additive" ;
  rdfs:comment "Vaccine component that is added to the immunogen by the vaccine manufacturer for a specific purpose. Additives include adjuvants, preservatives and stablizers, as well as materials that are added to affect pH and isotonicity." ;
  rdfs:subClassOf obo:VO_0000179 .

obo:VO_0016164 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0016003 .

obo:VO_0000237 a rdfs:Class ;
  rdfs:label "hypersensitivity to gentamicin" ;
  rdfs:subClassOf obo:VO_0000224 .

obo:VO_0019343 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003441 , obo:VO_0010444 , obo:VO_0010445 .

obo:VO_0004678 a rdfs:Class ;
  rdfs:label "RBD-rAAV-SARS-CoV vaccine" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0004666 a rdfs:Class ;
  rdfs:label "MVA-CHIKV vaccine" ;
  rdfs:subClassOf obo:VO_0002785 .

obo:VO_0017892 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017812 .

obo:VO_0020123 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide Injectable Solution [Meningovax-AC]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017813 .

obo:VO_0004853 a rdfs:Class ;
  rdfs:label "BEXSERO vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003359 .

obo:VO_0001606 a rdfs:Class ;
  rdfs:label "Avian Reovirus Killed Virus Vaccine (USDA: 1045.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001513 , obo:VO_0007748 .

obo:VO_0019523 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.005 MG/ML Injectable Suspension [Recombivax]" ;
  rdfs:subClassOf obo:VO_0003417 , obo:VO_0019535 .

obo:VO_0020456 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020441 .

obo:VO_0016291 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016026 .

obo:NCBITaxon_12475 a rdfs:Class ;
  rdfs:label "Hepatitis delta virus" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:VO_0016531 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0003913 a rdfs:Class ;
  rdfs:label "Fluad 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000362 , obo:VO_0004281 , obo:VO_0010431 .

obo:VO_0003244 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Recombivax]" ;
  rdfs:subClassOf obo:VO_0003243 .

obo:VO_0010423 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2021-2022" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0015706 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015570 , obo:VO_0015789 .

obo:VO_0003197 a rdfs:Class ;
  rdfs:label "Hepatitis A virus-Typhoid vaccine foreign to USA" ;
  rdfs:comment "A vaccine to protect individuals against infections caused by hepatitis A virus and typhoid fever bacteria." ;
  rdfs:subClassOf obo:VO_0000950 , obo:VO_0003444 , obo:VO_0010438 , obo:VO_0010451 .

obo:VO_0000499 a rdfs:Class ;
  rdfs:label "obsolete preventive infectious disease vaccine function" .

obo:VO_0016742 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] Box of 10" ;
  rdfs:subClassOf obo:VO_0016710 , obo:VO_0016768 .

obo:VO_0000820 a rdfs:Class ;
  rdfs:label "Aeromonas salmonicida vaccine" ;
  rdfs:comment "Aeromonas bacterial vaccine that is used to protect against Aeromonas salmonicida infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000589 .

obo:VO_0002178 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 17A1.1N)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0002593 a rdfs:Class ;
  rdfs:label "FTT0918 from Francisella tularensis" ;
  rdfs:comment "An FTT0918 mutant showed significantly reduced virulence in mice. Mice that recovered from infection with the mutant were protected 2 months later from challenge with wild type F. tularensis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0017807 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis 0.5 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0003276 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0020285 .

obo:VO_0019227 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0010039 a rdfs:Class ;
  rdfs:label "Plasmodium berghei P36p" ;
  rdfs:comment "A P36p protein that is part of Plasmodium berghei" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015475 .

obo:NCBITaxon_205488 a rdfs:Class ;
  rdfs:label "Ebola virus sp." ;
  rdfs:subClassOf obo:NCBITaxon_11266 .

obo:VO_0017450 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0017673 .

obo:NCBITaxon_1648 a rdfs:Class ;
  rdfs:label "Erysipelothrix rhusiopathiae" ;
  rdfs:subClassOf obo:NCBITaxon_1239 .

obo:VO_0002789 a rdfs:Class ;
  rdfs:label "Corynebacterium pseudotuberculosis vaccine" ;
  rdfs:comment "Vaccine against infection with Corynebacterium pseudotuberculosis." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003534 .

obo:VO_0007342 a rdfs:Class ;
  rdfs:label "autologous oxidized ovarian tumor cell lysate vaccine" ;
  rdfs:comment "A cancer vaccine that is composed of oxidized ovarian tumor cell lysate, with potential immunostimulatory and antineoplastic activities. The autologous oxidized ovarian tumor cell lysate vaccine exposes the immune system to an undefined amount of tumor-associated antigens (TAAs), which may result in the induction of both anti-tumor cytotoxic T-lymphocytes (CTLs) and antibody-dependent responses against TAA-expressing cells, leading to tumor cell lysis. Compared to non-oxidized tumor cell lysate vaccines, oxidized tumor cell lysate vaccines induce necrotic cell death, increase the immunogenicity of the TAAs and may enhance the anti-tumor immune response. Cyclophosphamide/Fludarabine Lymphodepletion and an immunomodulatory combination of Interferon-alpha Bevacizumab and Aspirin followed by adoptive transfer of vaccine-primed ex vivo CD3/CD28-costimulated peripheral blood autologous T cells and vaccination with whole tumor vaccine administered intradermally in combination with Bevacizumab in patients with recurrent ovarian cancer fallopian tube or primary peritoneal cancer may help treat their tumors. Patients will receive 5-10 million cells intradermally. " ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0004356 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis DNA vaccine pcDNA3.1+/Ag85A DNA encoding Ag85A" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:VO_0004167 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding HA of Equine influenza virus H3N8" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0019141 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0010968 a rdfs:Class ;
  rdfs:label "Bfr from B. melitensis biovar Abortus 2308" ;
  rdfs:comment "Brucella bacterioferritin is a protective antigen [PubMed: 11447155 ]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:OPL_0000325 a rdfs:Class ;
  rdfs:label "tachyzoite stage" ;
  rdfs:comment "A parasite lifecycle stage that parasite replicates rapidly within the host cell." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0005306 a rdfs:Class ;
  rdfs:label "TLR8 receptor role" ;
  rdfs:comment "A role of a material entity that binds to TLR8 and activates the receptor for pathogen recognition and activation of innate immunity." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0000018 a rdfs:Class ;
  rdfs:label "Brucella abortus DNA vaccine pcDNA-SOD" ;
  rdfs:comment "A Brucella abortus vaccine that expresses Cu/Zn SOD with DNA plasmid pcDNA. " ;
  rdfs:subClassOf obo:VO_0001225 .

obo:VO_0019258 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0019801 .

obo:VO_0015058 a rdfs:Class ;
  rdfs:label "Mumps Virus Vaccine Live, Jeryl Lynn Strain Injectable Product" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010442 .

obo:VO_0002012 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 11A1.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002372 .

obo:VO_0001677 a rdfs:Class ;
  rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000985 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0003740 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria Quadrivalent 2016-2017 Formula]" ;
  rdfs:subClassOf obo:VO_0003744 .

obo:VO_0004524 a rdfs:Class ;
  rdfs:label "classicals swine fever virus DNA vaccine pcDNA/E2 with TRIF" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001012 .

obo:VO_0018737 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 2000000000 ORGANISMS Delayed Release Oral Capsule [Vivotif Berna] Box of 3 by Paxvax Berna" ;
  rdfs:subClassOf obo:VO_0018736 .

obo:VO_0004277 a rdfs:Class ;
  rdfs:label "Brucella melitensis mucR mutant vaccine" ;
  rdfs:comment "A mucR mutant has a significantly reduced degree of colonization in mice and protects against wild type B. melitensis 16M" ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0007180 a rdfs:Class ;
  rdfs:label "Von Hippel-Lindau Peptide Vaccine" ;
  rdfs:comment "A cancer vaccine composed of peptides derived from a tumor-associated protein encoded by a mutated Von Hippel-Lindau (VHL) oncogene. VHL peptide vaccine may stimulate a cytotoxic T cell response against tumor cells expressing the VHL tumor-associated protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0011472 a rdfs:Class ;
  rdfs:label "Eimeria tenella DNA vaccine rBCG pMV261-Rho" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001137 .

obo:VO_0003374 a rdfs:Class ;
  rdfs:label "Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0003202 .

obo:VO_0001307 a rdfs:Class ;
  rdfs:label "non-ionic surfactant vesicles vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant consisting of multi-lamellar vesicles comprising a mixture of non-ionic surfactant (e.g., 1-monopalmitoyl-rac-glycerol), cholesterol and dicetyl phosphate used as a primary vaccine adjuvant for entrapped antigen." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0003105 a rdfs:Class ;
  rdfs:label "Lymerix vaccine" ;
  rdfs:comment "LYMErix [Lyme Disease Vaccine (Recombinant OspA)] is a noninfectious recombinant vaccine developed and manufactured by SmithKline Beecham Biologicals. The vaccine contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus." ;
  rdfs:subClassOf obo:VO_0004028 , obo:VO_0010479 .

obo:VO_0006020 a rdfs:Class ;
  rdfs:label "obsolete HPV unspecified formulation" .

obo:VO_0010231 a rdfs:Class ;
  rdfs:label "tuberculin skin test; purified protein derivative solution, intradermal" ;
  rdfs:subClassOf obo:NCIT_C85994 .

obo:VO_0007133 a rdfs:Class ;
  rdfs:label "Ovarian Tumor Antigen-activated Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A dendritic cell (DC)-based cancer vaccine composed of autologous dendritic cells (DCs) activated with an ovarian tumor cell lysate containing tumor-associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, the ovarian tumor antigen-activated autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against ovarian cancer cells expressing ovarian tumor cell-specific antigens, which may result in ovarian tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0002001 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:VO_0017744 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0017739 , obo:VO_0017741 , obo:VO_0017773 .

obo:VO_0004745 a rdfs:Class ;
  rdfs:label "vFP89-HA (H5N1 HPAI virus) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0017293 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.0936 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML [Tetravac]" ;
  rdfs:subClassOf obo:VO_0018779 .

obo:VO_0007698 a rdfs:Class ;
  rdfs:label "MUC1 peptide-poly-ICLC vaccine" ;
  rdfs:comment "A cancer vaccine containing mucus 1 (MUC1) peptide and the adjuvant poly-ICLC with potential immunostimulatory and antineoplastic activities. MUC1 peptide-poly-ICLC adjuvant vaccine may induce the host immune system to mount a cytotoxic T cell response against MUC1-expressing tumor cells. MUC1 peptide-poly-ICLC adjuvant vaccine in boosting systemic immunity to MUC1 in women with stage I-III 'triple-negative' [i.e., ER(-) PR(-) HER2/neu(-)] breast cancer. MUC1 peptide-Poly-ICLC vaccine could also work in preventing lung cancer in current and former smokers at high risk for lung cancer. Vaccines made from peptides may help the body build an effective immune response to kill cells. MUC1 peptide-Poly-ICLC vaccine may stimulate the body's immune system and slow or stop the changes from normal to pre-cancer to cancer." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0001697 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1651.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0015540 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Suspension [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0003416 , obo:VO_0010711 .

obo:VO_0010775 a rdfs:Class ;
  rdfs:label "Clostridium tetani protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:VO_0001510 a rdfs:Class ;
  rdfs:label "chicken anemia virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Chicken Anemia Virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0015515 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML [Fendrix]" ;
  rdfs:subClassOf obo:VO_0003230 .

obo:VO_0000911 a rdfs:Class ;
  rdfs:label "passive immunization using natural maternal antibody" ;
  rdfs:comment "passive immunization that Immunity is transferred from mother to fetus through placental transfer of IgG or colostral transfer of IgA." ;
  rdfs:subClassOf obo:VO_0000492 .

obo:VO_0007301 a rdfs:Class ;
  rdfs:label "Autologous Immunoglobulin Idiotype-KLH Conjugate Vaccine" ;
  rdfs:comment "A cancer vaccine composed of tumor-specific idiotype determinants derived from an individual's tumor cells which are conjugated to keyhole limpet hemocyanin, an immunostimulant carrier protein. When injected into the individual from whom the tumor cells were isolated, this vaccine may stimulate an antitumoral cytotoxic T-lymphocytic immune response." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0001252 a rdfs:Class ;
  rdfs:label "toxoid" ;
  rdfs:comment "is a bacterial toxin (usually an exotoxin) whose toxicity has been weakened or suppressed either by chemical (formalin) or heat treatment, while other properties, typically immunogenicity, are maintained." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:VO_0011144 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/whooper swan/Mongolia/3/05(H5N1))" ;
  rdfs:comment "Chickens immunized with attenuated Salmonella strains expressing the hemagglutinin (HA1) gene from a highly pathogenic avian influenza (HPAI) H5N1 (A/whooper swan/Mongolia/3/2005) demonstrated a statistically significant increase in survival compared to control groups [PubMed: 20406663]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:DOID_3069 a rdfs:Class ;
  rdfs:label "malignant astrocytoma"@en ;
  rdfs:comment "A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord."@en ;
  rdfs:subClassOf obo:DOID_0050687 , obo:DOID_3620 .

obo:VO_0002142 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis-Marek's Disease Serotypes 2 & 3, Modified Live & Live Marek's Disease Vector Vaccine (USDA: 16J1.R2)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002441 , obo:VO_0007748 .

obo:VO_0011187 a rdfs:Class ;
  rdfs:label "Spag-1" ;
  rdfs:comment "The trial vaccination of cattle against T. annulata using recombinant sporozoite antigens (SPAG-1 and p67) and/or merozoite antigens (TAMS 1-1 and 1-2). The aim of these trials was to try and enhance the levels of protection induced compared with previous trials. Different approaches were tried. SPAG-1 was expressed as a fusion protein with a His6 tag and then either incorporated into ISCOMs, with or without TAMS 1-1 and 1-2, or administered with RWL, a proprietary saponin-based adjuvant. Cross-protection studies were also performed by immunizing cattle with the T. parva sporozoite antigen, p67, and then challenging with a T. annulata sporozoite stabilate.All the data collected from these two trials indicate that SPAG-1 administered with RWL is better at inducing an effective immune response than SPAG-1 incorporated into ISCOMs, with or without the presence of merozoite antigens [PubMed: 9668470]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010825 .

obo:VO_0004360 a rdfs:Class ;
  rdfs:label "Hepatitis B DNA vaccine pCMV-S2.S encoding the HBV(ayw Strain) envelope protein." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000644 .

obo:VO_0016623 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Twinrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015004 .

obo:VO_0002409 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira CanicolaGrippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0002410 .

obo:VO_0019951 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluzone 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020482 .

obo:PATO_0001677 a rdfs:Class ;
  rdfs:label "inefficient" ;
  rdfs:comment "An efficiency quality inhering in a bearer by virtue of the bearer's lacking efficiency." ;
  rdfs:subClassOf obo:PATO_0001029 .

obo:VO_0002127 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus Vaccine (USDA: 14W5.22)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002401 , obo:VO_0007748 .

obo:VO_0016529 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0000488 a rdfs:Class ;
  rdfs:label "E. coli subunit vaccine using FyuA" ;
  rdfs:subClassOf obo:VO_0000628 , obo:VO_0001466 .

obo:VO_0004272 a rdfs:Class ;
  rdfs:label "pVAX-P1 DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001142 .

obo:VO_0015969 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 100" ;
  rdfs:subClassOf obo:VO_0003265 .

obo:VO_0019559 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flucelvax Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020333 .

obo:VO_0015966 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015734 , obo:VO_0015740 , obo:VO_0016050 .

obo:VO_0018379 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003346 .

obo:VO_0015555 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015524 .

obo:VO_0004667 a rdfs:Class ;
  rdfs:label "MVTT-HA-QH vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0003518 a rdfs:Class ;
  rdfs:label "Borreliella vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Borreliella." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003494 .

obo:VO_0017537 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:NCBITaxon_517 a rdfs:Class ;
  rdfs:label "Bordetella" ;
  rdfs:subClassOf obo:NCBITaxon_80840 .

obo:VO_0016226 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:VO_0019859 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Victoria/1/2020 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML / influenza B virus B/Washington/02/2019 antigen 158000000 UNT/ML [FluMist Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020353 .

obo:VO_0015234 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine (inactivated) strain HM175 / typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Injectable Suspension [ViATIM]" ;
  rdfs:subClassOf obo:VO_0015232 .

obo:VO_0000724 a rdfs:Class ;
  rdfs:label "cytomegalovirus vaccine" ;
  rdfs:subClassOf obo:VO_0000727 .

obo:VO_0000661 a rdfs:Class ;
  rdfs:label "Haemophilus vaccine" ;
  rdfs:comment "Vaccine that protects against Haemophilus infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0000188 a rdfs:Class ;
  rdfs:label "Dengue virus gene" ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0004492 a rdfs:Class ;
  rdfs:label "FeLV DNA vaccine gag/pol and env" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000843 .

obo:VO_0007691 a rdfs:Class ;
  rdfs:label "MDX-CTLA4 antibody/tyrosinase/gp100/MART-1 melanoma vaccine" ;
  rdfs:comment "A cancer vaccine composed of CTLA-4 antibody; tyrosinase, gp100, and MART-1 peptides; and incomplete Freund's adjuvant (IFA) with or without interleukin-12 in patients with resected stage III or IV melanoma." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0007567 a rdfs:Class ;
  rdfs:label "EF-1 Peptide Vaccine" ;
  rdfs:comment "A synthetic peptide derived from the protein ESW/FLI1 type 1 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-1 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FL1 type 1 fusion protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0011151 a rdfs:Class ;
  rdfs:label "LASVsSgp1 nucleoprotein" ;
  rdfs:comment "Vaccine efficacy trials in guinea pigs indicated that the nucleoprotein is capable of eliciting a protective immune response against a lethal dose of Lassa virus. Ninety-four percent of the animals vaccinated with V-LSN survived a Lassa virus challenge in which only 14% of unvaccinated animals and 39% of animals vaccinated with the New York Board of Health (NYBH) strain of vaccinia virus survived [PubMed: 2741340]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010763 .

obo:VO_0003899 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003898 .

obo:VO_0002376 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Vaccine-Clostridium Perfringens Types C & D-Escherichia Coli Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0002375 .

obo:VO_0020717 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 660000000 CFU" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017679 .

obo:VO_0002882 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine" ;
  rdfs:comment "A guaBA, clpP, and fliD mutant (CVD 1923) is attenuated in mice after oral immunization. This mutant is also protective, with a vaccine efficacy of 80% in mice against wild type challenge from Salmonella Typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0015280 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015282 , obo:VO_0019503 .

obo:VO_0017255 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Tetravac]" ;
  rdfs:subClassOf obo:VO_0017252 .

obo:VO_0010934 a rdfs:Class ;
  rdfs:label "HspB from Coxiella burnetii" ;
  rdfs:comment "The purified recombinant proteins, P1, HspB, and P1-HspB, and whole-cell antigen (WCA) of C. burnetii were used to immunize BALB/c mice. Protective immunity against Q fever was induced with a recombinant P1 antigen fused with HspB after Coxiella burnetii challenge [PubMed: 16481504 ]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010773 .

obo:VO_0016153 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0007429 a rdfs:Class ;
  rdfs:label "MVF-HER-2(597-626)/MVF-HER-2 (266-296) peptide vaccine" ;
  rdfs:comment "A combination peptide vaccine of 2 chimeric peptides of the promiscuous T cell epitope derived from measles virus fusion protein (MVF; amino acid residues 288-302) co-synthesized with B-cell epitopes derived from the HER-2/neu a.a. 597-626 and HER-2/neu a.a. 266-296, with potential antineoplastic activity. Vaccination with MVF-HER-2(597-626)/MVF-HER-2(266-296) peptide vaccine may be capable of inducing an active specific immune response, mounting a cytotoxic T-lymphocyte (CTL) response and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells that overexpress the HER-2 protein. The oncogenic protein HER-2, a member of the human epidermal growth factor receptor (EGFR) family of tyrosine kinases, is overexpressed in a variety of cancers and is correlated with increased tumor growth, progression and a poor prognosis. HER-2(597-626) corresponds to the binding site of trastuzumab on the extracellular domain IV of HER-2; HER-2 (266-296) corresponds to the binding site of pertuzumab on the dimerization loop of domain II of HER-2" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0003845 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0015014 .

obo:VO_0020220 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.1 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020218 .

obo:VO_0005402 a rdfs:Class ;
  rdfs:label "RQ3013 vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by Walvax Biotechnology and Shanghai RNACure Biopharma" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0002466 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus-Rabies Virus Vaccine" ;
  rdfs:subClassOf obo:VO_0000650 , obo:VO_0002408 .

obo:VO_0016710 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax]" ;
  rdfs:subClassOf obo:VO_0016673 , obo:VO_0016686 , obo:VO_0016719 .

obo:VO_0015291 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML [Epaxal]" ;
  rdfs:subClassOf obo:VO_0010713 , obo:VO_0015290 .

obo:VO_0018023 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 1000000 CELLS" ;
  rdfs:subClassOf obo:VO_0003835 .

obo:VO_0007494 a rdfs:Class ;
  rdfs:label "Hexapeptide melanoma vaccine" ;
  rdfs:comment "Gene name: gp100" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0002455 a rdfs:Class ;
  rdfs:label "Hirame rhabdovirus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Hirame rhabdovirus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0016605 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0016590 , obo:VO_0016597 .

obo:VO_0020876 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020900 .

obo:VO_0000477 a rdfs:Class ;
  rdfs:label "human Rabies vaccine" ;
  rdfs:comment "a Rabies virus vaccine against Rabies in human" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0010808 a rdfs:Class ;
  rdfs:label "Canine coronavirus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0016023 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015665 , obo:VO_0015770 .

obo:VO_0015273 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0015267 .

obo:VO_0001650 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1272.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0010112 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii ROP17" ;
  rdfs:comment "A ROP17 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0020817 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0019135 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010417 .

obo:VO_0017768 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated Injectable Solution [Pac Merieux]" ;
  rdfs:subClassOf obo:VO_0017806 .

obo:VO_0010823 a rdfs:Class ;
  rdfs:label "Eimeria tenella protein" ;
  rdfs:subClassOf obo:VO_0010822 .

obo:VO_0004902 a rdfs:Class ;
  rdfs:label "influenza A virus A/Victoria/361/2011 (H3N2) antigen" ;
  rdfs:comment """Recommended by WHO for Vaccines:
2013 Southern Hemisphere
2014 Southern Hemisphere
2012-2013 Northern Hemisphere
2013-2014 Northern Hemisphere""" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0011552 a rdfs:Class ;
  rdfs:label "Newcastle Disease Virus HN glycoprotein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0001222 .

obo:VO_0005317 a rdfs:Class ;
  rdfs:label "Baiya SARS-CoV-2 Vax 1 vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine by Baiya Phytopharm Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0016921 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 4 LFU/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017309 .

obo:VO_0021167 a rdfs:Class ;
  rdfs:label "0.3 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (XBB.1.5) 0.0333 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:NCBITaxon_9895 a rdfs:Class ;
  rdfs:label "Bovidae" ;
  rdfs:subClassOf obo:NCBITaxon_35500 .

obo:VO_0017733 a rdfs:Class ;
  rdfs:label "2 ML acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution [Tussoglobin] Box of 1" ;
  rdfs:subClassOf obo:VO_0017732 , obo:VO_0017734 , obo:VO_0017764 .

obo:VO_0002934 a rdfs:Class ;
  rdfs:label "Vibrio cholerae hemA mutant vaccine" ;
  rdfs:comment "A hemA mutant is highly attenuated in mice and rabbits and induces protection from challenge with wild type V. cholerae in rabbits" ;
  rdfs:subClassOf obo:VO_0000763 .

obo:NCBITaxon_1301 a rdfs:Class ;
  rdfs:label "Streptococcus" ;
  rdfs:subClassOf obo:NCBITaxon_91061 .

obo:VO_0004513 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi DNA vaccine encoding strain B31 OspA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000764 .

obo:VO_0018744 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Delayed Release Oral Capsule [Vivotif Berna]" ;
  rdfs:subClassOf obo:VO_0018743 .

obo:VO_0016488 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Gerke" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0011428 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus DNA vaccine encoding GatC" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001085 .

obo:VO_0005366 a rdfs:Class ;
  rdfs:label "XtendIII vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant that is oil-based adjuvant (Adjuvant XtendIII®; Grand Laboratories, Larchwood, IA)." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0007054 a rdfs:Class ;
  rdfs:label "VCL-CB01 vaccine" ;
  rdfs:comment "A vaccine consisting of two plasmids encoding the human cytomegalovirus (CMV) tegument phosphoprotein 65 (pp65), a major internal matrix protein, and glycoprotein B (gB), an important CMV component responsible for attachment and entry into cells, with immunostimulatory properties. Vaccination with VCL-CB01 may stimulate the host immune system to mount cellular and humoral immune responses against CMV positive cells, resulting in cell lysis." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0005487 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0016280 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015924 .

obo:VO_0017266 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adacel] Box of 5" ;
  rdfs:subClassOf obo:VO_0017265 , obo:VO_0017267 .

obo:VO_0011032 a rdfs:Class ;
  rdfs:label "PtxD" ;
  rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model.  These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:VO_0018551 a rdfs:Class ;
  rdfs:label "0.5 ML Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML Injectable Solution [Mumpsvax]" ;
  rdfs:subClassOf obo:VO_0018550 , obo:VO_0018666 .

obo:VO_0004337 a rdfs:Class ;
  rdfs:label "Ebola virus recombinant vector vaccine EBO7 encoding GP from SEBOV and ZEBOV" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000726 .

obo:VO_0012390 a rdfs:Class ;
  rdfs:label "ClfA" ;
  rdfs:comment "Mice immunized with recombinant ClfA and challenged with S. aureus developed less-severe arthritis than did mice immunized with a control antigen [PubMed: 11740733]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012355 .

obo:VO_0021115 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0020321 .

obo:VO_0004181 a rdfs:Class ;
  rdfs:label "Theileria annulata Tams1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000909 .

obo:VO_0015131 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015126 , obo:VO_0015296 .

obo:VO_0004218 a rdfs:Class ;
  rdfs:label "Biothrax Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0004215 , obo:VO_0018596 .

obo:VO_0002849 a rdfs:Class ;
  rdfs:label "Francisella tularensis purMCD mutant vaccine" ;
  rdfs:comment "A purMCD mutant in Francisella tularensis was attenuated. A low dose of the F. tularensis LVS delta purMCD mutant provided protection against subsequent lethal challenge with the LVS parental strain" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0002351 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Hardjo-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002352 .

obo:VO_0016664 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by ADL" ;
  rdfs:subClassOf obo:VO_0016626 .

obo:VO_0000000 a rdfs:Class ;
  rdfs:label "part of pathogen organism in vaccine" ;
  rdfs:comment "A pathogen component in vaccine that contains only a part of the pathogen organism instead of the whole organism." ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0015595 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0002582 a rdfs:Class ;
  rdfs:label "obsolete aroC from Edwardsiella tarda" ;
  rdfs:comment "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" .

obo:VO_0019411 a rdfs:Class ;
  rdfs:label "BCG, live, Tice strain 50 MG Injection" ;
  rdfs:subClassOf obo:VO_0018848 , obo:VO_0019412 .

obo:VO_0007156 a rdfs:Class ;
  rdfs:label "PSA:154-163(155L) Peptide Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a synthetic peptide with an amino acid sequence corresponding to positions 154-163 of the amino acid sequence for prostate-specific antigen (PSA) with a leucine substitution at position 155. Upon administration, PSA:154-163(155L) peptide vaccine may elicit a cytotoxic T-cell response against tumor cells that express PSA." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0016310 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015927 .

obo:VO_0011336 a rdfs:Class ;
  rdfs:label "Hsp60" ;
  rdfs:comment "Researchers  prepared an oral liposome-encapsulated recombinant Helicobacter pylori (Hp) heat shock protein 60 (Hsp60) vaccine and investigate its effect against Hp infection in mice.  rHsp60 plus CT (choleratoxin), liposome-encapsulated rHsp60 and liposome-encapsulated rHsp60 plus CT had protective rates against Hp infection of 73.3%, 66.7% and 86.7%, respectively [PubMed: 15897126]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010855 .

obo:VO_0018852 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:VO_0016891 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 LFU/ML Injectable Solution Box of 5 by Aventis" ;
  rdfs:subClassOf obo:VO_0016840 .

obo:VO_0007542 a rdfs:Class ;
  rdfs:label "Idiotype-pulsed autologous dendritic cell vaccine APC8020" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with tumor-derived clonal immunoglobulin (Ig) with potential immunostimulatory and antineoplastic activities. Upon administration, idiotype-pulsed autologous dendritic cell vaccine APC8020, containing idiotype (Id) protein structures that can be recognized by antibodies and by CD41 T lymphocytes and CD81 T lymphocytes, may stimulate antitumoral cytotoxic T lymphocyte (CTL) and antibody responses against Id-expressing tumor cells. The Id represents the unique antigenic determinants in the variable regions of the clonal Ig." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0000231 a rdfs:Class ;
  rdfs:label "pCMVLuc DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003424 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0019471 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0012185 .

obo:VO_0016121 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015877 .

obo:VO_0000440 a rdfs:Class ;
  rdfs:label "vaccine approval process" ;
  rdfs:comment "vaccine approval process is a processual entity that involves approval of a vaccine." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0020480 a rdfs:Class ;
  rdfs:label "Fluzone 2012-2013 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 , obo:VO_0010418 .

obo:VO_0011127 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Fukuoka/C29/85(H3N2))" ;
  rdfs:comment "The inoculation of HA vaccine prepared from influenza viruses A/Yamagata/120/86 (H1N1) or A/Fukuoka/C29/85 (H3N2) together with CTB provided partial protection against PR-8 infection in Balb/c mice [PubMed: 2781859]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0018237 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018253 .

obo:VO_0007679 a rdfs:Class ;
  rdfs:label "IL-2 peptide and GM-CSF-in-adjuvant melanoma vaccine" ;
  rdfs:comment "A cancer vaccine compromised of melanoma peptides plus GM-CSF-in-adjuvant. It is combined with low-dose IL-2 therapy, which could significantly enhance the immunologic efficacy." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0007122 a rdfs:Class ;
  rdfs:label "Vaccinia-Tyrosinase vaccine" ;
  rdfs:comment "A vaccine consisting of recombinant vaccinia virus, based on the modified vaccinia virus Ankara (MVA) that encodes the melanoma-associated antigen tyrosinase. Vaccination with vaccinia-tyrosinase may stimulate the host immune system to mount a cytotoxic T-cell response against tumor cells expressing tyrosinase. Tyrosinase is a melanoma-specific differentiation agent that catalyzes the synthesis of the melanin precursor L-3,4-dihydroxyphenylalanine (L-DOPA)." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0003013 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii OMPDC mutant vaccine" ;
  rdfs:comment "An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii" ;
  rdfs:subClassOf obo:VO_0000994 .

obo:VO_0012188 a rdfs:Class ;
  rdfs:label "Western equine encephalomyelitis virus vaccine" ;
  rdfs:comment "A vaccine that protects against Western equine encephalomyelitis virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0000046 a rdfs:Class ;
  rdfs:label "Fluvirin" ;
  rdfs:comment "Product Name: Influenza Virus Vaccine, Trivalent, Types A and B" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0018298 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018289 .

obo:VO_0019469 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide / Neisseria meningitidis Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003192 , obo:VO_0010437 , obo:VO_0010444 .

obo:VO_0002644 a rdfs:Class ;
  rdfs:label "lon from Salmonella Gallinarum" ;
  rdfs:comment "A lon mutant, in combination with a cpxR mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001420 .

obo:VO_0020277 a rdfs:Class ;
  rdfs:label "obsolete typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typhim VI]" .

obo:VO_0003647 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine 0.25 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003645 .

obo:VO_0011246 a rdfs:Class ;
  rdfs:label "ORF68" ;
  rdfs:comment "Monoclonal antibodies to gE  neutralize VZV in vitro in a complement- dependent manner [PubMed: 9125048]. Guinea pigs immunized with recombinant varicella-zoster virus (VZV) glycoproteins E (gE) and I (gI) developed antigen-specific antibodies in the sera, vitreous, and conjunctival washes. Sera from immunized animals neutralized both cell-free and cell-associated VZV, and peripheral blood lymphocytes proliferated in vitro in response to recombinant gE and gI and to antigens from VZV-infected cells. Immunized guinea pigs were inoculated intravitreally with VZV, which induces chronic uveitis. VZV DNA was more rapidly cleared and infectious VZV was isolated less frequently from the retinas of animals immunized with gE and gI compared with that in controls receiving adjuvant alone [PubMed: 9697709]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010792 .

obo:NCBITaxon_12637 a rdfs:Class ;
  rdfs:label "Dengue virus" ;
  rdfs:subClassOf obo:NCBITaxon_3044782 .

obo:VO_0015921 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 20" ;
  rdfs:subClassOf obo:VO_0015631 , obo:VO_0015686 , obo:VO_0016029 .

obo:VO_0016010 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015662 , obo:VO_0015801 .

obo:VO_0019363 a rdfs:Class ;
  rdfs:label "1 ML hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0019506 .

obo:VO_0001194 a rdfs:Class ;
  rdfs:label "biological sex datum" ;
  rdfs:comment "A measurement datum that represents the biological sex of an animal. The result can be represented using a discretized digit, for example, 0 = female; 1 = male." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0016233 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015906 .

obo:VO_0019380 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0020937 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0003507 , obo:VO_0004914 .

obo:VO_0003743 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2016-2017 Formula 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003742 .

obo:VO_0003604 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010313 , obo:VO_0010415 .

obo:VO_0007680 a rdfs:Class ;
  rdfs:label "IL15-DC vaccine" ;
  rdfs:comment "A cancer vaccine made with autologous dendritic cells that are manufactured with GM-CSF, IL15 and loaded with melanoma/HIV peptides and KLH; then activated with LPS and CD40 Ligand.IL15 is a T cell growth factor that could have a very important role in cancer immunotherapy. IL15 DCs are particularly efficient at priming functional melanoma specific CD8+ T cells. The use of IL15 in the manufacture of the DC vaccine could result in an improved immunotherapy product for melanoma patients." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0001235 a rdfs:Class ;
  rdfs:label "fungal vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a fungal vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0011061 a rdfs:Class ;
  rdfs:label "CAB613 putative peptidase" ;
  rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.  Of the 14 individually tested clones, CP #1 through CP #9 had positive relative protection scores.  CP #8 (CAB613, Oligopeptidase) was found to confer protection [PubMed: 15811648]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:VO_0016414 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 25 by Mtk" ;
  rdfs:subClassOf obo:VO_0015958 , obo:VO_0015964 .

obo:VO_0015028 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML [Varivax]" ;
  rdfs:subClassOf obo:VO_0000119 .

obo:VO_0000735 a rdfs:Class ;
  rdfs:label "Corynebacterium diphtheriae vaccine" ;
  rdfs:comment "A bacterial vaccine that protects against infection with Corynebacterium diphtheriae that causes Diphtheria." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003534 .

obo:NCBITaxon_263 a rdfs:Class ;
  rdfs:label "Francisella tularensis" ;
  rdfs:subClassOf obo:NCBITaxon_72273 .

obo:VO_0010319 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis Group B Membrane vesicles External Omv vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0019586 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Flublok 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003890 , obo:VO_0019584 .

obo:VO_0016978 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.08 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017442 .

obo:VO_0003711 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2018-2019 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003709 .

obo:VO_0003902 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2017-2018 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003899 .

obo:DOID_77 a rdfs:Class ;
  rdfs:label "gastrointestinal system disease"@en ;
  rdfs:comment "A disease of anatomical entity that is located_in the gastrointestinal tract."@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:VO_0004505 a rdfs:Class ;
  rdfs:label "avian influenza virus DNA vaccine pCMV-HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000461 .

obo:VO_0011213 a rdfs:Class ;
  rdfs:label "collagen binding, ancillary pilus subunit Cne" ;
  rdfs:comment "Mice were immunised i.n. with collagen-binding protein (CNE) and were subsequently subjected to infection with S. equi subsp. equi. A control group of mice was given only adjuvant. The CNE vaccinated group had a delayed onset of infection compared to the control group. Immunization with CNE led to significant protection from infection [PubMed: 16580099]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010816 .

obo:VO_0004692 a rdfs:Class ;
  rdfs:label "RCN-F1-V Yersinia pestis F1 and V vaccine" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0002179 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 17A2.1M)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0020204 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.2 MG/ML [Spikevax]" ;
  rdfs:subClassOf obo:VO_0010359 , obo:VO_0020203 .

obo:DOID_9210 a rdfs:Class ;
  rdfs:label "herpes zoster oticus"@en ;
  rdfs:comment "A viral infectious disease that results_in inflammation located_in facial nerve, which leads to paralysis of one side of the face, has_material_basis_in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The infection has_symptom vesicular rash of the ear or mouth, has_symptom tinnitus, has_symptom vertigo, has_symptom otalgia, and has_symptom headache."@en ;
  rdfs:subClassOf obo:DOID_4953 .

obo:VO_0017127 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension by Sanofi" ;
  rdfs:subClassOf obo:VO_0017073 .

obo:VO_0021021 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2000 PFU Injection" ;
  rdfs:subClassOf obo:VO_0021019 .

obo:NCBITaxon_234 a rdfs:Class ;
  rdfs:label "Brucella" ;
  rdfs:subClassOf obo:NCBITaxon_28211 .

obo:VO_0018112 a rdfs:Class ;
  rdfs:label "1 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution [Priorix] Box of 100 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018111 .

obo:VO_0001893 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4179.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002341 .

obo:VO_0020918 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Intanza]" ;
  rdfs:subClassOf obo:VO_0001248 , obo:VO_0020913 .

obo:VO_0010246 a rdfs:Class ;
  rdfs:label "assay platform variable" ;
  rdfs:comment "A variable representing the assay platform used (Nanopore,) etc." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0007468 a rdfs:Class ;
  rdfs:label "Interferon-gamma-expressing Adenovirus Vaccine ASN-002" ;
  rdfs:comment "A replication-defective adenoviral serotype 5 vector encoding a recombinant form of the human cytokine interferon-gamma (IFN-g), with potential antineoplastic and immunoregulatory activities. Upon intratumoral administration, the sustained expression of IFN-g by IFN-g-expressing adenovirus vaccine ASN-002 promotes a T-helper type 1 (Th1) immune response and inhibits the Th2-mediated cytokine production observed in many cutaneous lymphomas. IFN-g also mediates interleukin-12 (IL-12) production by antigen-presenting cells (APCs); activates macrophages, cytotoxic T-cells, and natural killer (NK) cells; upregulates major histocompatibility complex (MHC) molecules; and stimulates antibody-dependent cellular cytotoxicity (ADCC). Altogether, these IFN-g-mediated effects may result in both an inhibition of tumor cell proliferation and tumor cell death. Compared to IFN-g injections, the prolonged local production of IFN-g at the tumor site allows for higher efficacy and a reduction of systemic toxicity" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0016448 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Gerke" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0018660 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018804 .

obo:VO_0017595 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [T Wellcovax]" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0017187 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017630 .

obo:VO_0020760 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020758 , obo:VO_0020804 .

obo:VO_0020676 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain Injectable Suspension [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020675 .

obo:VO_0017686 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0017685 , obo:VO_0017742 .

obo:VO_0018795 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 .

obo:VO_0017577 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 2" ;
  rdfs:subClassOf obo:VO_0017555 .

obo:VO_0020495 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2022-2023 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010428 .

obo:VO_0007479 a rdfs:Class ;
  rdfs:label "GM-CSF-encoding Oncolytic Adenovirus CGTG-102 vaccine" ;
  rdfs:comment "A recombinant, oncolytic serotype 5/3 capsid-modified adenovirus encoding the immunostimulatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) with potential antineoplastic activity. Upon administration, the oncolytic adenovirus selectively infects and replicates in tumor cells, which may result in tumor cell lysis. Synergistically, GM-CSF (sargramostim) expressed by the oncolytic adenovirus enhances antigen presentation, promotes natural killer (NK) cell-mediated killing and causes a cytotoxic T cell (CTL) response against tumor cells harboring the oncolytic adenovirus, resulting in an immune-mediated tumor cell death. CGTG-102 is designed to replicate only in cells with defects in the p16/Rb/E2F pathway, attributed to a mutation common in many solid tumors. Replacement of the Ad5 capsid protein knob with a knob domain from serotype 3 causes higher transduction in cancer cells as compared to normal cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0018316 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Prefilled Syringe [VACCIN RABIQUE INACTIVE MERIEUX] by Sanofi" ;
  rdfs:subClassOf obo:VO_0018294 .

obo:VO_0015786 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0015596 .

obo:VO_0015312 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003430 .

obo:VO_0004898 a rdfs:Class ;
  rdfs:label "Influenza A virus A/Perth/16/2009 (H3N2) antigen" ;
  rdfs:comment """Recommended by WHO for Vaccines: 
2011-2012 Northern Hemisphere
2010 Southern Hemisphere
2011 Southern Hemisphere
2012 Southern Hemisphere
2010-2011 Northern Hemisphere""" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:BFO_0000038 a rdfs:Class ;
  rdfs:label "one-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:VO_0003333 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0018179 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015052 .

obo:VO_0003059 a rdfs:Class ;
  rdfs:label "Hepatitis D virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Hepatitis D virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0021156 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML Injection [Menactra]" ;
  rdfs:subClassOf obo:VO_0000071 , obo:VO_0000561 .

obo:VO_0005407 a rdfs:Class ;
  rdfs:label "COVID-19 mRNA vaccine by CanSino Biologics" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by CanSino Biologics Inc." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:NCBITaxon_544448 a rdfs:Class ;
  rdfs:label "Mycoplasmatota" ;
  rdfs:subClassOf obo:NCBITaxon_1783272 .

obo:VO_0015060 a rdfs:Class ;
  rdfs:label "Mumps Virus Vaccine Live, Jeryl Lynn Strain 25000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0015056 .

obo:VO_0019129 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010425 .

obo:VO_0018762 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension [Stamaril]" ;
  rdfs:subClassOf obo:VO_0018761 , obo:VO_0018767 .

obo:VO_0002415 a rdfs:Class ;
  rdfs:label "Canine Distemper-Hepatitis-Parainfluenza vaccine" ;
  rdfs:subClassOf obo:VO_0001471 , obo:VO_0001489 , obo:VO_0001526 , obo:VO_0012178 .

obo:VO_0019628 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flulaval Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020346 .

obo:VO_0019244 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0001819 a rdfs:Class ;
  rdfs:label "Arthrobacter Live Culture Vaccine (USDA: 1K11.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000645 , obo:VO_0001151 , obo:VO_0001217 , obo:VO_0001477 , obo:VO_0007748 .

obo:VO_0017277 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017232 , obo:VO_0017276 .

obo:VO_0003345 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0004027 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi DbpA Protein vaccine" ;
  rdfs:subClassOf obo:VO_0000764 .

obo:VO_0005158 a rdfs:Class ;
  rdfs:label "Oxford-AstraZeneca COVID-19 vaccine" ;
  rdfs:comment "A SARS-CoV2 recombinat vector vaccine made of a chimpanzee adenovirus-vectored vaccine expressing the SARS-CoV-2 spike protein" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005268 .

obo:VO_0017860 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 2.5 MG" ;
  rdfs:subClassOf obo:VO_0004886 .

obo:VO_0020026 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injectable Suspension [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020019 , obo:VO_0020478 .

obo:VO_0005381 a rdfs:Class ;
  rdfs:label "Mast cell activator small molecules vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0020956 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 .

obo:VO_0017404 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxin 10 LFU/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0017403 .

obo:VO_0020396 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0020377 , obo:VO_0020400 .

obo:VO_0015712 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015571 , obo:VO_0015789 .

obo:VO_0000962 a rdfs:Class ;
  rdfs:label "recombinant E. coli mutant vaccine" ;
  rdfs:comment "An E. coli vaccine that uses a live mutant by knocking out one gene(s) from a wild type E. coli." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000619 .

obo:VO_0020557 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Csl]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020861 .

obo:VO_0010714 a rdfs:Class ;
  rdfs:label "FSME - IMMUN" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000714 , obo:VO_0010454 .

obo:VO_0004577 a rdfs:Class ;
  rdfs:label "RHDV DNA vaccine pcDNA-VP60" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001382 .

obo:VO_0002559 a rdfs:Class ;
  rdfs:label "fla from Borrelia burgdorferi" ;
  rdfs:comment "A flagella-less mutant of Borrelia burgdorferi (HB19Fla-) was attenuated in immunodeficient SCID mice. Mice were challenged 28 days later with virulent strain Sh. 2 and were protected from challenge" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001410 .

obo:VO_0007108 a rdfs:Class ;
  rdfs:label "obsolete Synchotrope TA2M vaccine" ;
  rdfs:comment "A recombinant plasmid DNA vaccine that encodes two peptides, tyrosinase 207-216 and tyrosinase 1-17,  both of which are derived from human tyrosinase." .

obo:VO_0000762 a rdfs:Class ;
  rdfs:label "Leishmania vaccine" ;
  rdfs:comment "a protozoan vaccine that prevents against infection with Leishmania." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0018891 a rdfs:Class ;
  rdfs:label "influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0003138 a rdfs:Class ;
  rdfs:label "ACWY Vax vaccine" ;
  rdfs:comment "a licensed N. meningitidis vaccine that includes meningococcal polysaccharides from Groups A, C, Y and W-135 combined, and is manufactured by GSK." ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0018131 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Solution [M-M-RVAXPRO]" ;
  rdfs:subClassOf obo:VO_0018129 .

obo:VO_0012359 a rdfs:Class ;
  rdfs:label "YopH from Y. pestis strain: CO92, biovar: Orientalis" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0011299 a rdfs:Class ;
  rdfs:label "T. cruzi G2" ;
  rdfs:comment "The vaccine efficacy of a putative candidate antigen against T. cruzi infection and disease in a mouse model. C57BL/6 mice vaccinated with a T. cruzi G2-encoding plasmid and cytokine (interleukin-12 and granulocyte-macrophage colony-stimulating factor) expression plasmids elicited a strong Th1-type antibody response dominated by immunoglobulin G2b (IgG2b)/IgG1 isotypes. The dominant IgG2b/IgG1 antibody response was maintained after a challenge infection and was associated with 50% control of the acute-phase tissue parasite burden and an almost undetectable level of tissue parasites during the chronic phase, as determined by a sensitive T. cruzi 18S rRNA gene-specific real-time PCR approach [PubMed: 18550728]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0020338 a rdfs:Class ;
  rdfs:label "Flulaval 2012-2013 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000043 , obo:VO_0010418 .

obo:VO_0015759 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Fendrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015580 , obo:VO_0015818 .

obo:VO_0000177 a rdfs:Class ;
  rdfs:label "cancer vaccine" ;
  rdfs:comment "Vaccine that prevents or treats cancer." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005503 .

obo:OBI_0000429 a rdfs:Class ;
  rdfs:label "intraperitoneal administration" ;
  rdfs:comment "The administration of a substance into the peritoneum of an organism"@en ;
  rdfs:subClassOf obo:OBI_0600007 .

obo:VO_0001401 a rdfs:Class ;
  rdfs:label "Brucella suis gene" ;
  rdfs:comment "A Brucella gene that is from B. suis." ;
  rdfs:subClassOf obo:VO_0000790 .

obo:VO_0019414 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Quadracel]" ;
  rdfs:subClassOf obo:VO_0010736 .

obo:VO_0017555 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017548 .

obo:VO_0017142 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017141 .

obo:VO_0010019 a rdfs:Class ;
  rdfs:label "Leishmania  donovani LdyGCS" ;
  rdfs:comment "A LdyGCS protein that is part of Leishmania  donovani" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0002286 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.22)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002431 , obo:VO_0007748 .

obo:VO_0015331 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated 320 UNT/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0015325 , obo:VO_0015329 .

obo:VO_0007553 a rdfs:Class ;
  rdfs:label "IMT-1012 Immunotherapeutic vaccine" ;
  rdfs:comment "A multi-peptide cancer vaccine with potential immunostimulating and antineoplastic activities. IMT-1012 immunotherapeutic vaccine contains twelve different synthetic peptides or tumor associated antigens (TAAs), including cyclin I (CCNI), cyclin-dependent kinase CDC2, EDDRI and TACE/ADAM17, each of which is involved in a different pathway associated with tumor growth, survival, and metastasis. Each antigen in the vaccine elicits a specific cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing that antigen. This multi-antigen/multi-pathway targeting strategy provides broad immunotherapeutic coverage with respect to tumor complexity and heterogeneity and may result in enhanced vaccine efficacy." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0004738 a rdfs:Class ;
  rdfs:label "ALVAC-RHDV (vCP309) vaccine" ;
  rdfs:subClassOf obo:VO_0001382 .

obo:VO_0004633 a rdfs:Class ;
  rdfs:label "rHVT-H5 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0007353 a rdfs:Class ;
  rdfs:label "carcinoembryonic antigen peptide-1 vaccine" ;
  rdfs:comment "A cancer vaccine comprised of an epitope from the Carcinoembryonic Antigen obtained from cancer cells that can stimulate an immune response against tumor cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0017927 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017888 .

obo:VO_0001449 a rdfs:Class ;
  rdfs:label "Western equine encephalomyelitis virus gene" ;
  rdfs:comment "A viral gene that is from Western equine encephalomyelitis virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0002796 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis trpD mutant vaccine" ;
  rdfs:comment "A trpD mutant is highly attenuated in mice and induces more protection from challenge with wild type M. tuberculosis than that induced by the current vaccine BCG" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0007668 a rdfs:Class ;
  rdfs:label "H3.3K27M-specific peptide vaccine" ;
  rdfs:comment "A cancer vaccine composed of a peptide derived from histone H3.3 containing the amino acid substitution mutation lysine (Lys) 27-to-methionine (H3.3K27M), with potential immunoactivating and antineoplastic activities. Following the administration of the vaccine, the immune system may exert a cytotoxic T-lymphocyte (CTL)-mediated immune response against H3.3K27M-expressing tumor cells. A lysine 27-to-methionine (K27M) somatic mutation at histone H3 variant (H3.3) is a feature mutation in diffuse intrinsic pontine gliomas (DIPGs). This vaccine contains an H3.3-K27M targeted neoantigen peptide that can be taken up by antigen-presenting cells (APCs). APCs can present the peptide with the major histocompatibility complex (MHC) molecules on cell surface, thereby activating neoantigen-specific T cells and triggering corresponding cytotoxic T cell immune responses to eliminate H3.3-K27M-expressing DIPG cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0000456 a rdfs:Class ;
  rdfs:label "protection efficacy" ;
  rdfs:comment "Protection efficacy is an efficiency that is associated with protection by a biological product (e.g., vaccine) against a disease." ;
  rdfs:subClassOf obo:PATO_0001029 .

obo:VO_0017859 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.5 MG" ;
  rdfs:subClassOf obo:VO_0004886 .

obo:VO_0002633 a rdfs:Class ;
  rdfs:label "galE from Salmonella Typhi" ;
  rdfs:comment "A gal E mutant in strain Ty2 was isolated, attenuated, and protected mice against lethal challenge" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001419 .

obo:VO_0001844 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 15B5.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0002433 , obo:VO_0007748 .

obo:VO_0002636 a rdfs:Class ;
  rdfs:label "obsolete guaA from Salmonella spp." ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" .

obo:VO_0019635 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020493 .

obo:VO_0019460 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0001513 a rdfs:Class ;
  rdfs:label "avian reovirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Avian Reovirus (Avian orthoreovirus) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001468 , obo:VO_0003541 .

obo:NCBITaxon_5654 a rdfs:Class ;
  rdfs:label "Trypanosomatidae" ;
  rdfs:subClassOf obo:NCBITaxon_2611352 .

obo:VO_0021155 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML Prefilled Syringe [Menactra]" ;
  rdfs:subClassOf obo:VO_0000071 , obo:VO_0000561 .

obo:VO_0003700 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003698 .

obo:NCBITaxon_10244 a rdfs:Class ;
  rdfs:label "Monkeypox virus" ;
  rdfs:subClassOf obo:NCBITaxon_10242 .

obo:VO_0004380 a rdfs:Class ;
  rdfs:label "Lassa fever virus recombinant vector vaccine YFV17D/LASV-GPC encoding the glycoprotein precursor" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012177 .

obo:NCBITaxon_55987 a rdfs:Class ;
  rdfs:label "Isavirus salaris" ;
  rdfs:subClassOf obo:NCBITaxon_11308 .

obo:VO_0011079 a rdfs:Class ;
  rdfs:label "LpnA" ;
  rdfs:comment "Anti-lpnA MAbs conferred significant, although not complete, protection of nave C3H/HeN mice from lethal challenge with F. tularensis LVS when administered therapeutically [PubMed: 19176692]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:DOID_769 a rdfs:Class ;
  rdfs:label "neuroblastoma"@en ;
  rdfs:comment "An autonomic nervous system neoplasm that derives_from immature nerve cells."@en ;
  rdfs:subClassOf obo:DOID_1192 .

obo:VO_0017643 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [T Vaccinol]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0017116 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 10 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0017114 .

obo:VO_0007200 a rdfs:Class ;
  rdfs:label "Adenovirus 5-CD40 Ligand Vaccine" ;
  rdfs:comment "An adenovirus vector engineered to produce CD40 ligand. For use as a possible gene therapy agent. May induce apoptosis through the TNF pathway." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0001066 a rdfs:Class ;
  rdfs:label "Lactobacillus gasseri vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector that uses an attenuated Lactobacillus gasseri strain" ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0016411 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1 by Waymade" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0001683 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotype 1, Live Virus Vaccine (USDA: 16L1.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0001527 a rdfs:Class ;
  rdfs:label "avian paramyxovirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Avian Paramyxovirus infection" ;
  rdfs:subClassOf obo:VO_0000609 , obo:VO_0001461 .

obo:VO_0010192 a rdfs:Class ;
  rdfs:label "influenza, high-dose, split virus, quadrivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:NCBITaxon_10407 a rdfs:Class ;
  rdfs:label "Hepatitis B virus" ;
  rdfs:subClassOf obo:NCBITaxon_10405 .

obo:VO_0007193 a rdfs:Class ;
  rdfs:label "Abagovomab vaccine" ;
  rdfs:comment "A murine IgG1 monoclonal anti-idiotype antibody, containing a variable antigen-binding region that functionally mimics the three-dimensional structure of a specific epitope on the ovarian cancer tumor-associated antigen CA-125, with potential antineoplastic activity. With a variable antigen-binding region that acts as a surrogate antigen for CA-125, abagovomab may stimulate the host immune system to elicit humoral and cellular immune responses against CA-125-positive tumor cells, resulting in inhibition of tumor cell proliferation." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0007360 a rdfs:Class ;
  rdfs:label "CEA/Tetanus Toxoid T Helper Epitope Fusion Protein-Expressing DNA Plasmid Vaccine" ;
  rdfs:comment "A plasmid vaccine encoding wild type human carcinoembryonic antigen (CEA) fused to a tetanus toxoid T helper epitope, with potential antineoplastic activity. Upon vaccination and subsequent intradermal electroporation, CEA/tetanus toxoid T helper epitope fusion protein-expressing DNA plasmid vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells. CEA, a tumor associated antigen, is overexpressed in a variety of cancer cell types. The tetanus toxoid helper peptide epitope, obtained from the bacterial Clostridium tetani toxoid, binds to class II MHC molecules and increases the helper T-cell response thereby inducing an increased and long-term immune response." ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0005489 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0004929 a rdfs:Class ;
  rdfs:label "human adult age range at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004927 .

obo:VO_0018201 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injection" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0015301 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015299 , obo:VO_0015300 .

obo:VO_0016460 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0017356 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0017349 .

obo:VO_0001156 a rdfs:Class ;
  rdfs:label "avian pathogenic E. coli vaccine" ;
  rdfs:comment "a vaccine against avian pathogenic Escherichia coli (APEC) infection, a major problem for the poultry industry in the world." ;
  rdfs:subClassOf obo:VO_0000041 , obo:VO_0001461 .

obo:VO_0010872 a rdfs:Class ;
  rdfs:label "PagA from B. anthracis str. Ames Ancestor" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010757 .

obo:VO_0000951 a rdfs:Class ;
  rdfs:label "Bayovac CSF E2 vaccine" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001012 .

obo:VO_0018775 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:UBERON_0000042 a rdfs:Class ;
  rdfs:label "serous membrane" ;
  rdfs:comment "Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer." ;
  rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0010000 .

obo:VO_0000885 a rdfs:Class ;
  rdfs:label "vaccine preservative role" ;
  rdfs:comment "a role inhers in a vaccine component that when added into a vccine formmulation, it can prevent the growth of bacteria or fungi that inadvertently may be introduced into the vaccine during administrating process or the manufacturing process." ;
  rdfs:subClassOf obo:VO_0000415 .

obo:VO_0020484 a rdfs:Class ;
  rdfs:label "Fluzone High-Dose 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000079 , obo:VO_0010416 .

obo:VO_0007230 a rdfs:Class ;
  rdfs:label "Allogeneic Mesothelioma Tumor Lysate-pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with a mixture of lysates from five allogeneic mesothelioma tumor cell lines, with potential immunostimulatory and antineoplastic activities. Upon leukapheresis, DCs are loaded with allogeneic mesothelioma tumor cell lysates. Upon re-administration of the allogeneic mesothelioma tumor lysate-pulsed autologous DC vaccine, the immune system is exposed to an undefined amount of mesothelioma-associated antigens, which stimulates the induction of a specific cytotoxic T-lymphocyte (CTL) response against mesothelioma tumor cells and leads to tumor cell lysis" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005491 , obo:VO_0007657 .

obo:VO_0017105 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 20" ;
  rdfs:subClassOf obo:VO_0017102 , obo:VO_0017118 , obo:VO_0017572 .

obo:VO_0018588 a rdfs:Class ;
  rdfs:label "5 ML Anthrax Vaccine Adsorbed 0.1 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0004215 , obo:VO_0018596 .

obo:VO_0018928 a rdfs:Class ;
  rdfs:label "influenza B virus B/Washington/02/2019 antigen" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:VO_0010051 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum Pfen" ;
  rdfs:comment "A Pfen protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0000460 a rdfs:Class ;
  rdfs:label "equine influenza vaccine" ;
  rdfs:comment "an influenza virus vaccine against equine influenza viral infection" ;
  rdfs:subClassOf obo:VO_0000642 , obo:VO_0001472 .

obo:VO_0015701 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 20" ;
  rdfs:subClassOf obo:VO_0015569 , obo:VO_0015790 .

obo:VO_0020235 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain 500000000 UNT/ML [ACAM2000]" ;
  rdfs:subClassOf obo:VO_0020234 .

obo:VO_0005142 a rdfs:Class ;
  rdfs:label "ZF2001 vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine composed of the SARS-CoV-2 S protein receptor-binding domain produced in Chinese hamster ovary (CHO) cells and adjuvant aluminum hydroxide." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0002225 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46E5.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002390 , obo:VO_0007748 .

obo:VO_0002131 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.26)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002421 , obo:VO_0007748 .

obo:VO_0017504 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension [T-Immun Immuno] Box of 10" ;
  rdfs:subClassOf obo:VO_0017503 , obo:VO_0017505 .

obo:VO_0016927 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML / tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017390 .

obo:VO_0017997 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0017996 , obo:VO_0018038 .

obo:VO_0019788 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0016425 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 3 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015972 .

obo:VO_0004497 a rdfs:Class ;
  rdfs:label "avian influenza virus DNA vaccine pH5HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0007564 a rdfs:Class ;
  rdfs:label "Golnerminogene Pradenovec vaccine" ;
  rdfs:comment "A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005425 , obo:VO_0005426 , obo:VO_0005430 , obo:VO_0005496 , obo:VO_0007657 .

obo:VO_0017097 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0017096 , obo:VO_0017114 , obo:VO_0017568 .

obo:VO_0015993 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015659 , obo:VO_0015777 .

obo:VO_0018696 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 700000 PFU Powder for Oral Suspension [Rotarix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018695 .

obo:VO_0004305 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine HA-DNA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0007293 a rdfs:Class ;
  rdfs:label "Autologous Epstein-Barr Virus-Transformed B-Lymphoblastoid Cell Vaccine" ;
  rdfs:comment "A cell-based vaccine composed of autologous tumor cells fused with Epstein-Barr virus-transformed B-lymphoblastoid cells. Upon administration, this vaccine may stimulate a cytotoxic T cell response against tumor cells, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0007747 a rdfs:Class ;
  rdfs:label "authorized vaccine role" ;
  rdfs:comment "Vaccine role that indicates a vaccine has received emergency use authorization (EUA) from regulatory authorities for distribution and administration to the public." ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0004033 a rdfs:Class ;
  rdfs:label "Leishmania donovani Hsp70 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001142 .

obo:VO_0000407 a rdfs:Class ;
  rdfs:label "recombinant O. anthropi 49237SOD vaccine" ;
  rdfs:subClassOf obo:VO_0000957 .

obo:VO_0010991 a rdfs:Class ;
  rdfs:label "C3389" ;
  rdfs:comment "Active immunization of BALB/c mice with recombinant E. coli protein C3389 antigen in Freund's adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0003008 a rdfs:Class ;
  rdfs:label "Plasmodium berghei p36p mutant vaccine" ;
  rdfs:comment "Genetically attenuated P36p-deficient Plasmodium berghei sporozoites provide protection against sporozoites challenge in mice" ;
  rdfs:subClassOf obo:VO_0002513 .

obo:VO_0001140 a rdfs:Class ;
  rdfs:label "West Nile-Innovator DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000752 .

obo:VO_0017419 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0017382 , obo:VO_0017417 .

obo:DOID_526 a rdfs:Class ;
  rdfs:label "human immunodeficiency virus infectious disease"@en ;
  rdfs:comment "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0012369 a rdfs:Class ;
  rdfs:label "KatG" ;
  rdfs:comment "DNA vaccines encoding  KatG antigen fused to TPA signal sequences evoked  a significant protective response in mice aerogenically challenged with low doses of Mycobacterium tuberculosis Erdman 17 to 21 days after the final immunization [PubMed: 10456931]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0018305 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe [Rabipur] Box of 1" ;
  rdfs:subClassOf obo:VO_0018278 , obo:VO_0018312 .

obo:VO_0018603 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 770000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004824 .

obo:VO_0021096 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2022-2023 Northern Hemisphere vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003073 , obo:VO_0010428 .

obo:VO_0001189 a rdfs:Class ;
  rdfs:label "vaccine viability datum" ;
  rdfs:comment "A measurement datum that represents vaccine viability. 0 = live; 1 = irradiated; 2 = killed." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0017938 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec]" ;
  rdfs:subClassOf obo:VO_0017904 .

obo:VO_0019354 a rdfs:Class ;
  rdfs:label "0.7 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2023 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020496 .

obo:DOID_9538 a rdfs:Class ;
  rdfs:label "multiple myeloma"@en ;
  rdfs:comment "A myeloid neoplasm that is located_in the plasma cells in bone marrow."@en ;
  rdfs:subClassOf obo:DOID_4960 .

obo:CL_0000234 a rdfs:Class ;
  rdfs:label "phagocyte" ;
  rdfs:comment "Any cell capable of ingesting particulate matter via phagocytosis." ;
  rdfs:subClassOf obo:CL_0000219 .

obo:VO_0000006 a rdfs:Class ;
  rdfs:label "Afluria vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0002928 a rdfs:Class ;
  rdfs:label "Shigella sonnei virG/senA/senB mutant vaccine" ;
  rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ;
  rdfs:subClassOf obo:VO_0000679 .

obo:VO_0020009 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.12 MG/ML Prefilled Syringe [Fluzone High-Dose 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0020007 .

obo:VO_0001213 a rdfs:Class ;
  rdfs:label "Foot-and-mouth disease virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Foot-and-mouth disease virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000646 .

obo:VO_0019672 a rdfs:Class ;
  rdfs:label "Bacillus anthracis as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0001134 a rdfs:Class ;
  rdfs:label "live attenuated Brucella abortus vaccine" ;
  rdfs:comment "live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella abortus infection." ;
  rdfs:subClassOf obo:VO_0000108 , obo:VO_0001127 .

obo:VO_0004766 a rdfs:Class ;
  rdfs:label "rORFV-RabG vaccine" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0019266 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/North Carolina/04/2016 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020331 .

obo:VO_0016545 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by HVD" ;
  rdfs:subClassOf obo:VO_0015984 .

obo:PR_P0DTC4 a rdfs:Class ;
  rdfs:label "envelope small membrane protein (SARS-CoV-2)" ;
  rdfs:comment "Category=organism-gene. Note: 75 aa protein. A protein that is a translation product of the E gene in SARS-CoV-2." ;
  rdfs:subClassOf obo:VO_0004990 .

obo:VO_0021086 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010447 .

obo:VO_0003765 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [FluLaval Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003763 .

obo:VO_0007144 a rdfs:Class ;
  rdfs:label "Primary Prostate Cancer Tissue/hTERT/Survivin mRNA-loaded Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "An autologous dendritic cell (DCs) vaccine targeting prostate cancer with immunostimulating activity. The autologous DC vaccine is prepared via transfecting DCs with mRNAs extracted from primary prostate cancer tissue, and mRNAs of human telomerase reverse transcriptase (hTERT) and survivin. Upon administration, this DC vaccine may elicit a potent cytotoxic T-cell (CTL) response against prostate cancer cells, resulting in tumor cell death. Both hTERT and survivin are essential in neoplastic growth, and are considered to be universal tumor antigens." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0000024 a rdfs:Class ;
  rdfs:label "pVAX1 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0012166 a rdfs:Class ;
  rdfs:label "Rift Valley Fever virus vaccine" ;
  rdfs:comment "A vaccine that protects against Rift Valley Fever virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0001434 a rdfs:Class ;
  rdfs:label "Feline infectious peritonitis virus gene" ;
  rdfs:comment "A viral gene that is from Feline infectious peritonitis virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:NCBITaxon_9031 a rdfs:Class ;
  rdfs:label "Gallus gallus" ;
  rdfs:subClassOf obo:NCBITaxon_9005 .

obo:VO_0007015 a rdfs:Class ;
  rdfs:label "Recombinant Human MUC1-Oxidized Polymannose-pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cancer vaccine containing autologous dendritic cells pulsed with a fusion product of an epitope of human tumor-associated epithelial mucin 1 (MUC1) antigen and the vaccine adjuvant mannan (oxidized mannose), with potential antineoplastic activity. When the modified dendritic cells are returned to the patient, they may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the MUC1 antigen, resulting in tumor cell lysis. Addition of manna in this vaccine, enhances immune recognition. MUC1 antigen, a high-molecular-weight transmembrane glycoprotein, is overexpressed on many tumor cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0001093 a rdfs:Class ;
  rdfs:label "NYVAC vaccine vector" ;
  rdfs:comment "a vaccinia vaccine vector that uses the highly attenuated NYVAC  as vector" ;
  rdfs:subClassOf obo:VO_0000600 .

obo:VO_0020299 a rdfs:Class ;
  rdfs:label "Afluria 2011-2012 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000006 , obo:VO_0000578 , obo:VO_0010419 .

obo:VO_0007338 a rdfs:Class ;
  rdfs:label "autologous CMV-pp65-flLAMP mRNA loaded dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous dendritic cells (DCs) loaded with mRNA encoding the human cytomegalovirus (CMV) matrix protein pp65 (65 kDa lower matrix phosphoprotein; UL83) as a fusion protein with the full-length lysosome-associated membrane protein (flLAMP), with potential immunostimulatory and antineoplastic activities. The vaccine exposes the immune system to the CMV pp65 peptide, which may elicit a cytotoxic T-lymphocyte (CTL) response against CMV pp65-expressing tumor cells. The incorporation of flLAMP may route CMV pp-65 antigens into the lysosomal compartment, resulting in enhanced MHC class II antigen presentation, thereby promoting CD4-positive T-cell responses. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a powerful adjuvant capable of stimulating macrophage function, inducing proliferation and maturation of DCs, and is able to enhance T-lymphocyte stimulatory function. The vaccine can be used in combination with monoclonal antibodies, such as basiliximab, that can block tumor growth in different ways, as well as temozolomide, and radiation therpay. The combination of treatments may kill more tumor cells." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0005428 , obo:VO_0007657 , obo:VO_0007658 .

obo:OPL_0000243 a rdfs:Class ;
  rdfs:label "erythrocytic trophozoite stage" ;
  rdfs:comment "A trophozoite stage in some protozoan parasite life cycle that occurs in erythrocytes." ;
  rdfs:subClassOf obo:OPL_0000057 .

obo:VO_0011058 a rdfs:Class ;
  rdfs:label "Pomp90A" ;
  rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.   Protective clone CP #4 (OMP90A, pomp90A) was diluted 1/2000 in a non-protective sublibrary pool of clones. This CP #4-spiked sublibrary conferred protection.  Five clones were significantly more protective than the genes encoding fewer than 50 amino acids (CP #1 and 7, p-value of less than 0.05 when comparing lung weights). [PubMed: 15811648]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:VO_0011229 a rdfs:Class ;
  rdfs:label "EMP1" ;
  rdfs:comment "Immunized animals were challenged in vivo with various parasite strains or clones of malaria. Immunization with the PfEMP1-DBL1 alpha domain abolished the PfEMP1-dependent sequestration of the homologous strain in immunized rats and substantially inhibited parasite adhesion in immunized monkeys. Protection against sequestration of heterologous parasite strains was also confirmed by direct or indirect challenge in the rat model [PubMed: 17074852]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0017030 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017025 , obo:VO_0017505 .

obo:VO_0020375 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0003849 .

obo:NCBITaxon_102793 a rdfs:Class ;
  rdfs:label "H5N1 subtype" ;
  rdfs:subClassOf obo:NCBITaxon_11320 .

obo:VO_0002872 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium clpP mutant vaccine" ;
  rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0019606 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluad 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020309 .

obo:VO_0001506 a rdfs:Class ;
  rdfs:label "obsolete Bovine Parainfluenza 3 Virus vaccine" .

obo:VO_0011083 a rdfs:Class ;
  rdfs:label "D15" ;
  rdfs:comment "Purified rD15 was found to be highly immunogenic in mice, guinea pigs, and rabbits, and passive transfer of anti-rD15 antibodies protected infant rats from challenge with H. influenzae type b or type a in infant rat models of bacteremia [PubMed: 9284140]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:NCBITaxon_10796 a rdfs:Class ;
  rdfs:label "Porcine parvovirus" ;
  rdfs:subClassOf obo:NCBITaxon_1506574 .

obo:VO_0003389 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0018556 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0018555 , obo:VO_0018721 .

obo:VO_0003446 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000487 .

obo:VO_0004889 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010289 , obo:VO_0010444 .

obo:VO_0015893 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015622 , obo:VO_0015623 , obo:VO_0015730 , obo:VO_0015736 , obo:VO_0016010 .

obo:VO_0000713 a rdfs:Class ;
  rdfs:label "vaccine allergen disposition" ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:VO_0000191 a rdfs:Class ;
  rdfs:label "arlacel A vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is an emulsifier called Arlacel A." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0017078 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017077 .

obo:VO_0017649 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [Tetasorbat]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0011010 a rdfs:Class ;
  rdfs:label "LolA" ;
  rdfs:comment "Using a mouse plague model, YPO1377 (lolA) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0010065 a rdfs:Class ;
  rdfs:label "Plasmodium vivax TRAP" ;
  rdfs:comment "A TRAP protein that is part of Plasmodium vivax" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015473 .

obo:IDO_0000586 a rdfs:Class ;
  rdfs:label "infection"@en ;
  rdfs:comment "A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0018694 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 700000 PFU Powder for Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0018692 , obo:VO_0018693 , obo:VO_0018699 .

obo:VO_0003367 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010292 , obo:VO_0010444 .

obo:VO_0000922 a rdfs:Class ;
  rdfs:label "monosodium glutamate stabliizer" ;
  rdfs:comment "a vaccine stablizer that is based on monosodium glutamate. " ;
  rdfs:subClassOf obo:VO_0003035 .

obo:VO_0019447 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 25 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0018454 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 1" ;
  rdfs:subClassOf obo:VO_0018432 , obo:VO_0018438 .

obo:VO_0001118 a rdfs:Class ;
  rdfs:label "Corynebacterium pseudotuberculosis vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector that uses a Corynebacterium pseudotuberculosis strain as the vaccine vector" ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0003239 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Recombivax]" ;
  rdfs:subClassOf obo:VO_0003237 .

obo:NCBITaxon_1489388 a rdfs:Class ;
  rdfs:label "Euteleosteomorpha" ;
  rdfs:subClassOf obo:NCBITaxon_186625 .

obo:VO_0017228 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0017227 .

obo:VO_0018104 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0018103 , obo:VO_0018238 .

obo:VO_0004507 a rdfs:Class ;
  rdfs:label "PRRSV DNA vaccine pIRESorf5/IFN-Gamma" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001802 .

obo:VO_0000151 a rdfs:Class ;
  rdfs:label "immunized" ;
  rdfs:comment "an organismal quality that indicates an organism (e.g., human) is immunized against a disease." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:VO_0018437 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumopur] Box of 20" ;
  rdfs:subClassOf obo:VO_0018421 .

obo:VO_0016219 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:VO_0010722 a rdfs:Class ;
  rdfs:label "Infanrix -IPV/Hib vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000744 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0004186 a rdfs:Class ;
  rdfs:label "Salmonella typimurium Vi4072 vaccine" ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0004830 a rdfs:Class ;
  rdfs:label "RotaTeq Oral Liquid Product" ;
  rdfs:subClassOf obo:VO_0000097 , obo:VO_0010448 .

obo:VO_0005287 a rdfs:Class ;
  rdfs:label "LiT4 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017508 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017507 , obo:VO_0017513 .

obo:OAE_0000097 a rdfs:Class ;
  rdfs:label "vaccine-induced adverse event" ;
  rdfs:comment "an adverse event that is induced by a vaccination." ;
  rdfs:subClassOf obo:OAE_0000004 .

obo:VO_0016908 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.016 MG/ML / Bordetella pertussis 0.1 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0016907 , obo:VO_0017289 .

obo:VO_0000973 a rdfs:Class ;
  rdfs:label "E. coli Shiga toxin 2B vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0016259 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015919 .

obo:VO_0003549 a rdfs:Class ;
  rdfs:label "Rubivirus vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Rubivirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0020473 a rdfs:Class ;
  rdfs:label "Fluvirin 2012-2013 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000046 , obo:VO_0010418 .

obo:VO_0016691 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.2 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0010711 a rdfs:Class ;
  rdfs:label "Engerix-B vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000644 , obo:VO_0000714 , obo:VO_0004914 , obo:VO_0010439 .

obo:VO_0018618 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus Prefilled Syringe [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0011558 , obo:VO_0018617 .

obo:VO_0003733 a rdfs:Class ;
  rdfs:label "Afluria 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000006 , obo:VO_0000578 , obo:VO_0010431 .

obo:VO_0016088 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015870 .

obo:VO_0003352 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003201 .

obo:NCBITaxon_186625 a rdfs:Class ;
  rdfs:label "Clupeocephala" ;
  rdfs:subClassOf obo:NCBITaxon_7898 .

obo:VO_0001151 a rdfs:Class ;
  rdfs:label "Piscirickettsia salmonis vaccine" ;
  rdfs:comment "Vaccine that protects against Piscirickettsia salmonis infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0020579 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020872 .

obo:VO_0007048 a rdfs:Class ;
  rdfs:label "TARP 29-37-9V peptide vaccine" ;
  rdfs:comment "A peptide-based cancer vaccine, consisting of amino acid residues 29 through 37 of T cell receptor gamma alternate reading frame protein (TARP) with a leucine-to-valine substitution at position 9, with potential immunostimulatory and antineoplastic activities. Upon administration, TARP 29-37-9V peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against TARP-expressing tumor cells, which may result in decreased tumor cell proliferation. The leucine-to-valine substitution at position 9 of this peptide improves its immunogenicity. The nuclear protein TARP is commonly expressed on prostate and breast cancer cells and is highly immunogenic." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0017559 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0017556 , obo:VO_0017579 .

obo:VO_0011091 a rdfs:Class ;
  rdfs:label "HTNVsSgp1" ;
  rdfs:comment "Passive transfer of spleen cells from mice immunized with rNP (HTNVsSgp1) conferred partial protection or prolongation of time to death from fatal Hantaan virus infection in suckling mice which were challenged with Hantaan virus at 40 LD50 (survival rate: 43%) or 4 LD50 (survival rate: 43%) [PubMed: 8517793]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010768 .

obo:VO_0000658 a rdfs:Class ;
  rdfs:label "Rotavirus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Rotavirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003542 .

obo:VO_0002501 a rdfs:Class ;
  rdfs:label "Mycobacterium avium vaccine" ;
  rdfs:comment "A vaccine that protects against Mycobacterium avium." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000592 .

obo:VO_0010182 a rdfs:Class ;
  rdfs:label "influenza, live, quadrivalent, intranasal" ;
  rdfs:subClassOf obo:VO_0001178 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017919 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injectable Solution [Menveo]" ;
  rdfs:subClassOf obo:VO_0017819 .

obo:VO_0010473 a rdfs:Class ;
  rdfs:label "nonmechanistic correlate of immune protection" ;
  rdfs:comment "Correlated profile of immune protection that is not a mechanistic causal agent of protection, but is still predictive of vaccine efficacy." ;
  rdfs:subClassOf obo:VO_0010472 .

obo:VO_0011198 a rdfs:Class ;
  rdfs:label "MIC10" ;
  rdfs:comment """This study used an immunisation/challenge model of transplacental transmission, based on the Qs mouse with an Nc-Liverpool challenge to investigate the vaccine potential of a number of formulations based on four recombinant proteins of N. caninum.  A mixture of MIC10 and p24B produced partial protection against transplacental transmission of N. caninum in this mouse model [PubMed: 18789996].

Note:  MIC10 must be used in conjunction with p24B in order to confer protection against N. caninum.""" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0005089 a rdfs:Class ;
  rdfs:label "GLS-5310 vaccine" ;
  rdfs:comment "A SARS-CoV-2 plasmid DNA vaccine developed by GeneOne Life Science." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0001107 a rdfs:Class ;
  rdfs:label "Modified Vaccinia Ankara (MVA) virus vaccine vector" ;
  rdfs:comment "a vaccinia virus vector that uses the Modified Vaccinia Ankara (MVA) virus. " ;
  rdfs:subClassOf obo:VO_0000600 .

obo:VO_0002878 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium cya/crp mutant vaccine" ;
  rdfs:comment "A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0000253 a rdfs:Class ;
  rdfs:label "pECK DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015764 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015584 , obo:VO_0015819 .

obo:VO_0012177 a rdfs:Class ;
  rdfs:label "Lassa Fever Virus vaccine" ;
  rdfs:comment "A vaccine that protects against Lassa Fever Virus." ;
  rdfs:subClassOf obo:VO_0000609 .

obo:VO_0011443 a rdfs:Class ;
  rdfs:label "E. coli Hma protein vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0017299 a rdfs:Class ;
  rdfs:label "Bordetella pertussis / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000942 , obo:VO_0017808 , obo:VO_0020836 .

obo:VO_0015908 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Fendrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015625 , obo:VO_0015758 , obo:VO_0016019 .

obo:VO_0002190 a rdfs:Class ;
  rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.24)" .

obo:VO_0001270 a rdfs:Class ;
  rdfs:label "Montanide ISA51 vaccine adjuvant" ;
  rdfs:comment "A Montanide vaccine adjuvant that is a vaccine adjuvant composed of a light mineral oil and a surfactant system designed to make a water-in-oil emulsion." ;
  rdfs:subClassOf obo:VO_0001271 .

obo:VO_0002076 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass Type, Killed Virus Vaccine (USDA: 12M5.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0010297 a rdfs:Class ;
  rdfs:label "Influenza A virus (H1N1) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003498 .

obo:VO_0002962 a rdfs:Class ;
  rdfs:label "obsolete Feline infectiour peritonitis virus 3abc mutant vaccine" ;
  rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" .

obo:VO_0001980 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:VO_0015023 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Tenivac]" ;
  rdfs:subClassOf obo:VO_0015024 .

obo:VO_0011483 a rdfs:Class ;
  rdfs:label "obsolete Td Polio Adsorbed" ;
  rdfs:comment "This term is obsolete since there is another term with the same name." .

obo:VO_0004479 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine pIMS-120 encoding PA" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0015982 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Gen Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015646 , obo:VO_0015760 , obo:VO_0016061 .

obo:VO_0004316 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 recombinant vector vaccine BHVl/BRSVG" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000987 .

obo:VO_0016067 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015864 .

obo:VO_0005429 a rdfs:Class ;
  rdfs:label "liver cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is used against liver canceer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0002337 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0000620 , obo:VO_0001523 , obo:VO_0002338 .

obo:VO_0019385 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0010883 a rdfs:Class ;
  rdfs:label "LcrE" ;
  rdfs:comment "The immunogenicity and protective effect of recombinant LcrE protein combined either with Freund's or Alum adjuvant were investigated in mice. The immunization with both protocols resulted in a significant reduction of the number of viable C. pneumoniae in the lungs after challenge. Results confirm that LcrE induces protective immunity in mice [PubMed: 19451031]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010794 .

obo:VO_0002707 a rdfs:Class ;
  rdfs:label "TK from Equid herpesvirus" ;
  rdfs:comment "A thymidine kinase-deficient mutant (PR1) is attenuated in mice and induced significant protection from challenge with wild type EHV-1 5 weeks after vaccination. In foals, PR1 also showed attenuation; however, the mutant induced only partial protection from challenge with EHV-1" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0019108 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe [Fluzone Intradermal 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019107 , obo:VO_0020486 .

obo:NCBITaxon_176 a rdfs:Class ;
  rdfs:label "Leptospira interrogans serovar Hardjo" ;
  rdfs:subClassOf obo:NCBITaxon_173 .

obo:VO_0015843 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015638 .

obo:VO_0004868 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.005 MG/ML" ;
  rdfs:subClassOf obo:VO_0015013 .

obo:VO_0016807 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Pur] Box of 10" ;
  rdfs:subClassOf obo:VO_0016728 , obo:VO_0016749 , obo:VO_0016819 .

obo:VO_0002893 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium htrA mutant vaccine" ;
  rdfs:comment "A htrA mutant in Salmonella typhimurium is attenuated and provides protection in mice against an oral challenge with virulent S. typhimurium SL1344" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0020907 a rdfs:Class ;
  rdfs:label "Influenza A virus Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0015988 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015485 , obo:VO_0015772 .

obo:VO_0015835 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 25 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015607 .

obo:VO_0001387 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine encoding G2" ;
  rdfs:comment "A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi G2 protein." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0016299 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Veron" ;
  rdfs:subClassOf obo:VO_0016027 .

obo:VO_0000513 a rdfs:Class ;
  rdfs:label "Quail pox vaccine" ;
  rdfs:comment "a Pox vaccine for Quail pox" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000512 .

obo:VO_0003939 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 6 Vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003300 .

obo:VO_0011404 a rdfs:Class ;
  rdfs:label "Hepatitis B virus DNA vaccine pVAX-PS" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000644 .

obo:VO_0003493 a rdfs:Class ;
  rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010305 , obo:VO_0010415 .

obo:VO_0003776 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2018-2019 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003774 .

obo:VO_0002775 a rdfs:Class ;
  rdfs:label "Bacillus anthracis mntA deletion mutant vaccine" ;
  rdfs:comment "An mntA deletion mutant, generated by allelic replacement, in Bacillus anthracis was attenuated and provided protection for guinea pigs against lethal spore dose (60 LD50) of the virulent B. anthracis Vollum strain" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0019286 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Flulaval 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019285 , obo:VO_0020340 .

obo:VO_0011460 a rdfs:Class ;
  rdfs:label "Coccidioides posadasii subunit PMP1 protein vaccine" ;
  rdfs:comment "a Coccidioides vaccine that contains C. posadasii PMP1 protein" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012179 .

obo:VO_0018040 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 2 (MEF-1) 100000 CELLS" ;
  rdfs:subClassOf obo:VO_0003836 .

obo:VO_0006096 a rdfs:Class ;
  rdfs:label "ALFQ vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant that is an AS01-mimic, liposomal adjuvant of a TLR4 agonist and saponin." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:DOID_11166 a rdfs:Class ;
  rdfs:label "Human papillomavirus infectious disease"@en ;
  rdfs:comment "A viral infectious disease that has_material_basis_in human papillomaviruses, which establish productive infections only in the stratified epithelium of the skin or mucous membranes. These viruses cause warts and sometimes tumors. They are transmitted_by sexual contact."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0005207 a rdfs:Class ;
  rdfs:label "Advax vaccine adjuvant" ;
  rdfs:comment "A carbohydrate vaccine adjuvant derived from delta inulin" ;
  rdfs:subClassOf obo:VO_0001359 .

obo:VO_0005120 a rdfs:Class ;
  rdfs:label "MERS England1 S DNA Vaccine" ;
  rdfs:comment "A MERS DNA vaccine made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0004900 .

obo:VO_0004825 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010449 .

obo:VO_0002067 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease Standard & Variant, Killed Virus Vaccine (USDA: 12G5.42)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002365 , obo:VO_0007748 .

obo:VO_0018718 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML [Typherix]" ;
  rdfs:subClassOf obo:VO_0010744 , obo:VO_0018717 .

obo:VO_0016107 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 20 by Mtk" ;
  rdfs:subClassOf obo:VO_0015994 .

obo:VO_0020047 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [FluLaval 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020336 .

obo:VO_0003818 a rdfs:Class ;
  rdfs:label "influenza A virus A/Slovenia/2903/2015 (H1N1) antigen" ;
  rdfs:comment "RXAUI: 9278618" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0017621 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] Box of 10" ;
  rdfs:subClassOf obo:VO_0017620 , obo:VO_0017626 .

obo:VO_0015781 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 3" ;
  rdfs:subClassOf obo:VO_0015595 .

obo:VO_0016465 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0021133 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:VO_0016172 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015892 , obo:VO_0015894 .

obo:VO_0017378 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Repevax]" ;
  rdfs:subClassOf obo:VO_0018786 .

obo:VO_0017588 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 8 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0003405 .

obo:VO_0017519 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0020140 a rdfs:Class ;
  rdfs:label "mumps virus vaccine live, Jeryl Lynn strain Injectable Solution [Mumpsvax]" ;
  rdfs:subClassOf obo:VO_0000074 , obo:VO_0020139 .

obo:VO_0007722 a rdfs:Class ;
  rdfs:label "personal neoantigen cancer vaccine" ;
  rdfs:comment "A cancer vaccine designed to target the unique immunogenic mutations arising in each patient's tumor. Peptide binding to MHC is a critical gateway to both the initiation of a T-cell immune response by the antigen presenting cell (APC), and to the detection and elimination of tumor cells presenting the particular peptide by the stimulated cytotoxic T lymphocyte (CTL). The attraction of neoantigens as cancer targets for the immune system results from the structural and geographical features of the mutation. Neoantigen peptides are only found in tumor cells, so CTLs should show exquisite specificity, reducing the opportunity for autoimmune disease." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0005350 a rdfs:Class ;
  rdfs:label "naNO-COVID vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine containing a T-cell priming specific cocktail of Coronaviruses peptides mounted on a gold nanoparticle." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0011353 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus DNA vaccine encoding E protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000665 .

obo:VO_0004143 a rdfs:Class ;
  rdfs:label "Shigella flexneri 2a strain CVD 1205 vaccine" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0003034 a rdfs:Class ;
  rdfs:label "sugar vaccine stabilizer" ;
  rdfs:comment "a vaccine stabilizer that is specifically made by a sugar." ;
  rdfs:subClassOf obo:VO_0000853 .

obo:VO_0011173 a rdfs:Class ;
  rdfs:label "Mtb72F" ;
  rdfs:comment "Our lead construct, Mtb72F, codes for a 72-kDa polyprotein genetically linked in tandem in the linear order Mtb32(C)-Mtb39-Mtb32(N).  All forms of Mtb72F immunization tested resulted in the protection of C57BL/6 mice against aerosol challenge with a virulent strain of M. tuberculosis [PubMed: 15187142]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0016135 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0016866 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 20 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016821 .

obo:PATO_0001241 a rdfs:Class ;
  rdfs:label "physical object quality" ;
  rdfs:comment "A quality which inheres in a continuant." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:VO_0017610 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017682 .

obo:VO_0004030 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi OspC protein vaccine" ;
  rdfs:subClassOf obo:VO_0000764 .

obo:VO_0001578 a rdfs:Class ;
  rdfs:label "Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1841.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0000990 , obo:VO_0001220 .

obo:VO_0003103 a rdfs:Class ;
  rdfs:label "Rabipur vaccine" ;
  rdfs:comment "A vaccine used to help prevent rabies infection in people who either have been, or are at risk of being bitten, licked or scratched by an animal infected with rabies virus." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010448 .

obo:UBERON_0001062 a rdfs:Class ;
  rdfs:label "anatomical entity" ;
  rdfs:comment "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:VO_0020400 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0020383 .

obo:VO_0020848 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0017574 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur] Box of 10" ;
  rdfs:subClassOf obo:VO_0017573 , obo:VO_0017576 .

obo:VO_0016114 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015872 .

obo:VO_0003807 a rdfs:Class ;
  rdfs:label "Flumist Quadrivalent 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000982 , obo:VO_0010432 .

obo:VO_0003924 a rdfs:Class ;
  rdfs:label "Fluad 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003912 .

obo:VO_0016999 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [T Immun] Box of 10" ;
  rdfs:subClassOf obo:VO_0016996 , obo:VO_0017020 , obo:VO_0017486 .

obo:VO_0019617 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flublok Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020326 .

obo:VO_0015498 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003421 .

obo:VO_0017049 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017521 .

obo:VO_0003445 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 2000000000 UNT Delayed Release Oral Capsule" ;
  rdfs:subClassOf obo:VO_0003447 .

obo:VO_0001495 a rdfs:Class ;
  rdfs:label "Porcine rotavirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Porcine rotavirus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000658 .

obo:VO_0017108 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017573 .

obo:VO_0019436 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Haemophilus capsular oligosaccharide 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0019427 .

obo:VO_0017216 a rdfs:Class ;
  rdfs:label "50 ML tetanus toxoid vaccine, inactivated 1.5 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017215 , obo:VO_0017467 .

obo:VO_0015108 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension [Havrix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015107 .

obo:VO_0017389 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.05 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017326 .

obo:VO_0018506 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0018502 .

obo:VO_0012387 a rdfs:Class ;
  rdfs:label "DbpA" ;
  rdfs:comment "Mice immunized with recombinant DbpA protein are protected against challenge with Borrelia burgdorferi [PubMed: 11035759]." ;
  rdfs:subClassOf obo:VO_0012368 .

obo:VO_0001666 a rdfs:Class ;
  rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.57)" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:VO_0001281 a rdfs:Class ;
  rdfs:label "obsolete immunization target role of bacterial pathogen" .

obo:VO_0010260 a rdfs:Class ;
  rdfs:label "vaccine study design variable" ;
  rdfs:comment "A study design variable that is used in a vaccine study." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0018204 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Prefilled Syringe [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018203 .

obo:VO_0017916 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injectable Solution [Menactra]" ;
  rdfs:subClassOf obo:VO_0017819 .

obo:VO_0007279 a rdfs:Class ;
  rdfs:label "Autologous CD40L-expressing B-CLL Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous, B-chronic lymphocytic leukemia (B-CLL) cells harvested from a patient and transduced with an adenoviral vector encoding the gene for the human CD40 ligand (CD40L; TRAP; CD154), with potential immunostimulating and antineoplastic activities. Upon reintroduction into the patient, the autologous CD40L-expressing B-CLL vaccine expresses the co-stimulatory molecule CD40L, which binds to its cognate receptor, CD40, on antigen presenting cells (APC). This induces apoptosis, stimulates maturation and proliferation of APCs, and facilitates a cytotoxic T-lymphocyte (CTL) response against tumor cells. CD40L is a type II membrane protein that binds to CD40, which is a cell surface receptor that belongs to the tumor necrosis factor (TNF) receptor superfamily." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0016520 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0004528 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine pVAX-TgMIC13" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:NCBITaxon_11318 a rdfs:Class ;
  rdfs:label "Thogotovirus dhoriense" ;
  rdfs:subClassOf obo:NCBITaxon_11308 .

obo:VO_0000803 a rdfs:Class ;
  rdfs:label "vaccine storage in freezer" ;
  rdfs:comment "vaccine storage that is executed in freezer under 0^C." ;
  rdfs:subClassOf obo:VO_0000800 .

obo:VO_0016458 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015975 .

obo:VO_0002655 a rdfs:Class ;
  rdfs:label "relA from Salmonella Gallinarum" ;
  rdfs:comment "A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001420 .

obo:VO_0017941 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0017927 .

obo:VO_0015472 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi protein" ;
  rdfs:subClassOf obo:VO_0010771 .

obo:VO_0020249 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.008 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML Injectable Suspension [Prevnar]" ;
  rdfs:subClassOf obo:VO_0000090 , obo:VO_0010210 , obo:VO_0010445 .

obo:VO_0018096 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Prefilled Syringe [Priorix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018095 .

obo:VO_0004465 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine xenogeneic DNA encoding murine tyrosinase" ;
  rdfs:comment "Gene name: Tyrosinase" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0011162 a rdfs:Class ;
  rdfs:label "L. donovani HASPB1" ;
  rdfs:comment "Study demonstrated for the first time that a recombinant stage-specific hydrophilic surface protein of Leishmania donovani, recombinant hydrophilic acylated surface protein B1 (HASPB1), is able to confer protection against experimental challenge with L. donovani in BALB/c mice [PubMed: 11120835]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0011068 a rdfs:Class ;
  rdfs:label "Env" ;
  rdfs:comment "Study describes experiments which demonstrate that the vaccine, (EURIFEL FeLV; Merial) that expresses the FeLV env and gag protective genes, is effective against any oronasal FeLV challenge. The protection was shown to be solid against an oronasal challenge one year after the initial vaccination, and was effective against a very severe 'in-contact' challenge [PubMed: 12934796]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010806 .

obo:VO_0010878 a rdfs:Class ;
  rdfs:label "YopD from Y. pestis CO92" ;
  rdfs:comment "The type III secretion apparatus encoded on the low-calcium response (LCR) virulence plasmid, pCD1 in strain KIM5, of Y. pestis is a conserved virulence mechanism that is absolutely required for virulence of Y. pestis. YscF is a surface localized protein required both to secrete Yops and to translocate toxins into eukaryotic cells. YscF polymerization is possibly required for a YscF needle to puncture eukaryotic cell membranes. It is also likely that YscF and its homologs function to provide a base that a translocon complex is built upon, or that YscF builds a conduit from the bacterium to the eukaryotic membrane - this suggestion seems more likely given that other proteins such as YopB, YopD, and LcrV are also required for translocation into eukaryotic cells. YscF is thought to be a surface-expressed protein in Y. pestis and is required for virulence. YscF has been found to function as a protective antigen against experimental plague infection [PubMed: 15978133]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0003074 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent - Southern Hemisphere Formulation" ;
  rdfs:comment "Product Name: Influenza Virus Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0010415 .

obo:VO_0004409 a rdfs:Class ;
  rdfs:label "Adjuvant arthritis DNA vaccine CII encoding type II collagen" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002823 .

obo:NCBITaxon_9823 a rdfs:Class ;
  rdfs:label "Sus scrofa" ;
  rdfs:subClassOf obo:NCBITaxon_91561 .

obo:VO_0000242 a rdfs:Class ;
  rdfs:label "CFU reduction assay" ;
  rdfs:comment "CFU reduction assay is an assay that measures the reduction of the colony forming units of infected pathogens in vaccine-vaccinated animals compared to nonvaccinated animals." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0020725 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Solution [ImmuCyst] Box of 1" ;
  rdfs:subClassOf obo:VO_0020724 , obo:VO_0020728 .

obo:VO_0001423 a rdfs:Class ;
  rdfs:label "Vibrio cholerae gene" ;
  rdfs:comment "A bacterial gene that is from Vibrio cholerae." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0002108 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.29)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0004198 a rdfs:Class ;
  rdfs:label "VVr expressing L. infantum P37/LACK vaccine" ;
  rdfs:subClassOf obo:VO_0012159 .

obo:VO_0000863 a rdfs:Class ;
  rdfs:label "Pirodog vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000649 , obo:VO_0001074 .

obo:VO_0001044 a rdfs:Class ;
  rdfs:label "Vibrio cholerae vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector that uses an attenuated Vibrio cholerae strain" ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0020401 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution [Typhim V] by Sanofi" ;
  rdfs:subClassOf obo:VO_0020386 .

obo:VO_0001162 a rdfs:Class ;
  rdfs:label "specification of vaccination-challenge interval" ;
  rdfs:comment "specification of time interval after vaccination for challenge is a plan specification that specifies the time interval after vacciation for challenge" ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:VO_0018265 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Prefilled Syringe [Rabipur]" ;
  rdfs:subClassOf obo:VO_0018272 .

obo:VO_0004841 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0004837 .

obo:VO_0019332 a rdfs:Class ;
  rdfs:label "0.5 ML measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML / mumps virus vaccine live, Jeryl Lynn strain 40000 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML / varicella-zoster virus vaccine live (Oka-Merck) strain 20000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0021152 .

obo:VO_0004327 a rdfs:Class ;
  rdfs:label "Lymphocytic choriomeningitis virus DNA vaccine pCMV-NP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003044 .

obo:VO_0007375 a rdfs:Class ;
  rdfs:label "Dinitrophenyl-Modified Autologous Renal Cell Carcinoma Tumor cell Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous renal cell carcinoma (RCC) tumor cells modified with the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of DNP-modified autologous renal cell carcinoma tumor cell vaccine may induce a cytotoxic T-lymphocyte (CTL) response against renal cell carcinoma tumor cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0004878 a rdfs:Class ;
  rdfs:label "Adenovirus Type 7 Vaccine Live Pill" ;
  rdfs:subClassOf obo:VO_0004877 .

obo:VO_0001741 a rdfs:Class ;
  rdfs:label "Bordetella Bronchiseptica Avirulent Live Culture Vaccine (USDA: 1081.00)" ;
  rdfs:subClassOf obo:VO_0000394 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0018186 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus Injection" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0016960 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur] by Novartis" ;
  rdfs:subClassOf obo:VO_0016959 .

obo:VO_0003874 a rdfs:Class ;
  rdfs:label "Flublok 2012-2013 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000978 , obo:VO_0010418 .

obo:VO_0010725 a rdfs:Class ;
  rdfs:label "meningococcal polysaccharide vaccine, Groups A & C, Menomune A/C" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010444 .

obo:VO_0004064 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis TbpA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0020126 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML / meningococcal polysaccharide vaccine group W-135 0.1 MG/ML / meningococcal polysaccharide vaccine group Y 0.1 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0017820 .

obo:VO_0010102 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii ISP3" ;
  rdfs:comment "A ISP3 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0010445 a rdfs:Class ;
  rdfs:label "licensed human orynebacterium diphtheriae vaccine" ;
  rdfs:comment "Corynebacterium diphtheriae vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000735 .

obo:VO_0007556 a rdfs:Class ;
  rdfs:label "live-attenuated Listeria monocytogenes-encoding EGFRvIII-NY-ESO-1 vaccine ADU-623" ;
  rdfs:comment "A live-attenuated, double-deleted strain of the Gram-positive bacterium Listeria monocytogenes (Lm) encoding a mutant form of the tumor associated antigens, epidermal growth factor receptor (EGFRvIII) and the cancer/testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, live-attenuated Listeria monocytogenes encoding EGFRvIII-NY-ESO-1 vaccine targets dendritic cells and expresses EGFRvIII and NY-ESO-1. This promotes both a potent innate immune response and an adaptive immune response involving the recruitment and activation of T lymphocytes against EGFRvIII and NY-ESO-1-expressing tumor cells, which results in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0007657 .

obo:VO_0015802 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 100" ;
  rdfs:subClassOf obo:VO_0015493 .

obo:VO_0002321 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4BC5.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002460 , obo:VO_0007748 .

obo:VO_0007368 a rdfs:Class ;
  rdfs:label "Dendritic Cell Tumor Cell Lysate Vaccine" ;
  rdfs:comment "A vaccine composed of dendritic cells pulsed with tumor cells lysates that stimulate a potent and specific cell mediated anti-tumor immune response." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0006005 a rdfs:Class ;
  rdfs:label "diphtheria antitoxin" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000508 , obo:VO_0010445 .

obo:VO_0017989 a rdfs:Class ;
  rdfs:label "0.5 ML poliomyelitis virus type 1 brunhilde 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution [Poliovaccine Ssi] by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0017988 .

obo:VO_0011004 a rdfs:Class ;
  rdfs:label "YPMT1.84 (F1 capsule antigen)" ;
  rdfs:comment "Intranasal immunization with flagellin and the F1 antigen was protective against intranasal challenge with virulent Y. pestis CO92, with 93 to 100% survival of immunized mice. Lastly, vaccination of cynomolgus monkeys with flagellin and a fusion of the F1 and V antigens of Y. pestis induced a robust antigen-specific IgG antibody response [PubMed: 16428759]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0017960 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017931 .

obo:VO_0011155 a rdfs:Class ;
  rdfs:label "Beta-tubulin" ;
  rdfs:comment "Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani. Results demonstrated that liposomal LD51 (beta-tubulin) reduced parasite burden by 72%-75% [PubMed: 19503834]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:NCBITaxon_594 a rdfs:Class ;
  rdfs:label "Salmonella enterica subsp. enterica serovar Gallinarum" ;
  rdfs:subClassOf obo:NCBITaxon_59201 .

obo:VO_0011342 a rdfs:Class ;
  rdfs:label "TcrP" ;
  rdfs:comment "The immunogenicity of a 48-kDa T-cell-reactive protein (TCRP) was investigated. Immunization of BALB/c and C3H/HeN mice with the rTCRP affords a modest but significant level of protection against an intraperitoneal challenge with C. immitis. It is suggested that the rTCRP may be able to contribute to a multicomponent vaccine designed to stimulate CMI response against the parasitic cycle of C. immitis." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010853 .

obo:VO_0010084 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi TSSA" ;
  rdfs:comment "A TSSA protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0011169 a rdfs:Class ;
  rdfs:label "P phosphoprotein" ;
  rdfs:comment "Lewis rats were immunized with recombinant vaccinia virus (VV) expressing various proteins of measles virus (MV). VVP (Phosphoprotein) -immunized rats were partially protected from MV challenge [PubMed: 1833505]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010784 .

obo:VO_0015750 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015815 .

obo:VO_0002113 a rdfs:Class ;
  rdfs:label "Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002417 , obo:VO_0007748 .

obo:VO_0016757 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.2 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016691 .

obo:NCBITaxon_504568 a rdfs:Class ;
  rdfs:label "Salmoninae" ;
  rdfs:subClassOf obo:NCBITaxon_8015 .

obo:VO_0017667 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Prefilled Syringe [Tetanol]" ;
  rdfs:subClassOf obo:VO_0003400 .

obo:VO_0001398 a rdfs:Class ;
  rdfs:label "vaccine containing DNA vaccine for priming and Ad vector vaccine for boosting" ;
  rdfs:comment "a prime-boost vaccine with a DNA vaccine priming that contains a Ad vector vaccine for boosting" ;
  rdfs:subClassOf obo:VO_0000401 .

obo:VO_0002767 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae ApxIC mutant vaccine" ;
  rdfs:comment "In the intra-peritoneal mouse model, the virulence of the mutant strain decreased at least 100 fold compared with the parent strain. The mutant was evaluated as a potential vaccine using a vaccination-challenge trial. The death number and lung lesion score in the vaccinated pigs given the serovar 1 challenge were obviously lower than those in the unvaccinated pigs" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0002400 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0002402 .

obo:DOID_399 a rdfs:Class ;
  rdfs:label "tuberculosis"@en ;
  rdfs:comment "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:VO_0002889 a rdfs:Class ;
  rdfs:label "obsolete Salmonella enterica fliC/guaB mutant vaccine" ;
  rdfs:comment "A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica" .

obo:VO_0021144 a rdfs:Class ;
  rdfs:label "influenza virus vaccine 2022-2023 (quadrivalent - Darwin/Wisconsin/Austria/Phuket) Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0004170 a rdfs:Class ;
  rdfs:label "recombinant vaccinia virus encoding HA from Influenza B virus (Strain B/England/222/82) vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000642 .

obo:VO_0021000 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 PFU Injection [Varivax]" ;
  rdfs:subClassOf obo:VO_0020998 , obo:VO_0020999 .

obo:VO_0020238 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain Injectable Solution [ACAM2000]" ;
  rdfs:subClassOf obo:VO_0020237 .

obo:VO_0015066 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML" ;
  rdfs:subClassOf obo:VO_0015067 .

obo:VO_0015919 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015631 , obo:VO_0015684 , obo:VO_0016027 .

obo:VO_0001628 a rdfs:Class ;
  rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1232.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0003203 a rdfs:Class ;
  rdfs:label "Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML" ;
  rdfs:subClassOf obo:VO_0003199 .

obo:VO_0004255 a rdfs:Class ;
  rdfs:label "recombinant PA vaccine with Poly(I:C) adjuvant" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000484 .

obo:DOID_15 a rdfs:Class ;
  rdfs:label "reproductive system disease"@en ;
  rdfs:comment "A disease of anatomical entity that is located_in reproductive system organs."@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:VO_0019205 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017830 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML [Menjugate]" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0010726 , obo:VO_0017877 .

obo:NCBITaxon_200644 a rdfs:Class ;
  rdfs:label "Flavobacteriales" ;
  rdfs:subClassOf obo:NCBITaxon_976 .

obo:VO_0007665 a rdfs:Class ;
  rdfs:label "GM.CD40L cell vaccine" ;
  rdfs:comment "A cancer vaccine composed of irradiated tumor cells transduced with granulocyte-macrophage colony-stimulating factor (GM-CSF) and CD40-ligand (CD40L) genes. The vaccine may stimulate an anti-tumoral dendritic cell-mediated host immune response. Universal GM-CSF-producing and CD40L-expressing bystander cell line is used to form an autologous tumor cell-based vaccine for patients with mantle cell lymphoma in order to make the body build an effective immune response to kill cancer cells. It can be used in combination with Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, Dexamethasone, and IL-2. The vaccine can be done with bystander and autologous tumor cells for patients with malignant melanoma. It can also be combined with lenalidomide for patients with myelodysplastic syndrome (MDS)." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0017323 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000942 , obo:VO_0017799 .

obo:VO_0016940 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 25 LFU/ML / Pertussis Vaccine 8 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution [Tri-Immunol Im] by Lederle Products" ;
  rdfs:subClassOf obo:VO_0016939 .

obo:VO_0017548 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0011393 a rdfs:Class ;
  rdfs:label "Marek's Disease Virus Vaccine rFPV/gB1" ;
  rdfs:subClassOf obo:VO_0012162 .

obo:VO_0020257 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0003345 .

obo:VO_0011439 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii MSP1 and MSP4/5 proteins subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0002514 .

obo:VO_0003834 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010447 .

obo:VO_0017075 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0017074 , obo:VO_0017114 , obo:VO_0017557 .

obo:VO_0019766 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hawaii/66/2019 (H1N1) antigen 158000000 UNT/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML / influenza B virus B/Washington/02/2019 antigen 158000000 UNT/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0003142 a rdfs:Class ;
  rdfs:label "obsolete clinical trial vaccine role" ;
  rdfs:comment "A vaccine role that indicates a clinical trial status of a vaccine" .

obo:VO_0002056 a rdfs:Class ;
  rdfs:label "Bursal Disease-Reovirus Killed Virus Vaccine (USDA: 12D5.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002385 , obo:VO_0007748 .

obo:VO_0004779 a rdfs:Class ;
  rdfs:label "NYVAC-SIV vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0000682 a rdfs:Class ;
  rdfs:label "Shigella flexneri 2a LPS vaccine complexed with Neisseria meningitidis proteosomes vaccine" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:OPL_0000400 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii sporozoite stage" ;
  rdfs:comment "A sporozoite stage in the Plasmodium yoelii." ;
  rdfs:subClassOf obo:OPL_0000152 , obo:OPL_0000300 , obo:OPL_0000415 .

obo:VO_0001795 a rdfs:Class ;
  rdfs:label "Lawsonia Intracellularis Avirulent Live Culture Vaccine (USDA: 10L1.00)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001105 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0010446 a rdfs:Class ;
  rdfs:label "licensed human papillomavirus vaccine" ;
  rdfs:comment "human papillomavirus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000667 .

obo:VO_0010361 a rdfs:Class ;
  rdfs:label "TICOVAC vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000952 .

obo:NCBITaxon_766 a rdfs:Class ;
  rdfs:label "Rickettsiales" ;
  rdfs:subClassOf obo:NCBITaxon_28211 .

obo:DOID_1240 a rdfs:Class ;
  rdfs:label "leukemia"@en ;
  rdfs:comment "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells."@en ;
  rdfs:subClassOf obo:DOID_2531 .

obo:VO_0017080 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 25 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017079 .

obo:VO_0007000 a rdfs:Class ;
  rdfs:label "Oncolytic Adenovirus Encoding GM-CSF Vaccine" ;
  rdfs:comment "A recombinant oncolytic adenovirus encoding the immunohematopoietic cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with potential antineoplastic activity. Upon administration, the oncolytic adenovirus selectively infects and replicates in tumor cells, which may result in tumor cells lysis. Synergistically, GM-CSF (sargramostim) expressed by the oncolytic adenovirus may promote a cytotoxic T cell response against tumor cells harboring the oncolytic adenovirus, resulting in an immune-mediated tumor cell death." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0002764 a rdfs:Class ;
  rdfs:label "obsolete OMPDC from Toxoplasma gondii" ;
  rdfs:comment "An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii" .

obo:VO_0017609 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 80" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0004835 a rdfs:Class ;
  rdfs:label "Quadracel vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0004833 .

obo:VO_0019989 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Fluzone 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019977 .

obo:VO_0020829 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML Injectable Solution [HibTITER] Box of 5" ;
  rdfs:subClassOf obo:VO_0020828 , obo:VO_0020830 .

obo:VO_0018313 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] by Novartis" ;
  rdfs:subClassOf obo:VO_0018290 .

obo:VO_0003222 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 18C vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0011326 a rdfs:Class ;
  rdfs:label "CEL-170/4" ;
  rdfs:comment "Researcherse tested the ability of the galactose-specific adherence lectin of E. histolytica to elicit a protective immune response in conjunction with Freund's incomplete and complete adjuvants.  Four independent trials demonstrated complete protection from amebic liver abscess formation in 67% of lectin-immunized gerbils.  The gerbil antilectin antibodies were shown by Western immunoblotting to be directed to the heavy subunit (CEL-170/4) but not the light subunit of the lectin [PubMed: 1987067]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010852 .

obo:VO_0000050 a rdfs:Class ;
  rdfs:label "HIV based lentivirus vaccine vector" ;
  rdfs:comment "a lentivirus vaccine vector that uses a HIV strain as the vector" ;
  rdfs:subClassOf obo:VO_0000359 .

obo:VO_0003214 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Poliovirus-Haemophilus B-Hepatitis B vaccine" ;
  rdfs:subClassOf obo:VO_0000664 , obo:VO_0000732 , obo:VO_0000746 .

obo:VO_0001532 a rdfs:Class ;
  rdfs:label "Pigeon Pox Live Virus Vaccine (USDA: 1881.12)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001220 , obo:VO_0001481 , obo:VO_0007748 .

obo:VO_0004391 a rdfs:Class ;
  rdfs:label "Marburg virus recombinant vector vaccine MBGV GP" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012163 .

obo:VO_0011530 a rdfs:Class ;
  rdfs:label "Leishmania donovani DNA vaccine encoding KMP-11" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001142 .

obo:VO_0017711 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension [Infanrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017708 .

obo:VO_0019388 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [ACEL-IMUNE]" ;
  rdfs:subClassOf obo:VO_0017799 , obo:VO_0018770 .

obo:VO_0016768 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0016719 .

obo:VO_0017638 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 100" ;
  rdfs:subClassOf obo:VO_0017631 .

obo:VO_0017725 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0017713 , obo:VO_0017786 .

obo:VO_0001549 a rdfs:Class ;
  rdfs:label "Feline Leukemia Live Canarypox Vector Vaccine (USDA: 1555.R3)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000843 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0020714 a rdfs:Class ;
  rdfs:label "BCG, live, Connaught strain 20000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017679 .

obo:VO_0015283 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015279 , obo:VO_0019502 .

obo:VO_0003597 a rdfs:Class ;
  rdfs:label "Fluzone 2018-2019 high-dose vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000079 , obo:VO_0003594 .

obo:VO_0019772 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Injectable Suspension [Afluria Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0020304 .

obo:VO_0016075 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015868 .

obo:VO_0006102 a rdfs:Class ;
  rdfs:label "oligonucleotide vaccine adjuvant" ;
  rdfs:comment "A nucleic acid vaccine adjuvant that is primarily composed of oligonucleotide." ;
  rdfs:subClassOf obo:VO_0006109 .

obo:VO_0000090 a rdfs:Class ;
  rdfs:label "Prevnar vaccine" ;
  rdfs:comment "STN: BLA 101094" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000424 , obo:VO_0000556 .

obo:VO_0018663 a rdfs:Class ;
  rdfs:label "Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0015056 .

obo:VO_0020887 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020907 .

obo:VO_0016776 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0016720 .

obo:VO_0000519 a rdfs:Class ;
  rdfs:label "human ACPP" ;
  rdfs:subClassOf obo:VO_0000516 , obo:VO_0001232 .

obo:VO_0020799 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 UNT" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0019465 .

obo:VO_0015243 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0017766 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0017762 .

obo:VO_0016331 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0004598 a rdfs:Class ;
  rdfs:label "GSK1437174A vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0012168 .

obo:VO_0000814 a rdfs:Class ;
  rdfs:label "vaccination dose" ;
  rdfs:comment "A dose of vaccine that is used in a vaccination. Vaccination dose may be and may be not the same as the vaccine dose." ;
  rdfs:subClassOf obo:OBI_0000984 .

obo:VO_0002310 a rdfs:Class ;
  rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49F6.23)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002464 , obo:VO_0007748 .

obo:VO_0002571 a rdfs:Class ;
  rdfs:label "purK from B. melitensis" ;
  rdfs:comment "A purE/purK mutant of B. melitensis 16M was attenuated in mice when given intraperitoneally. Nine weeks after immunization, mice were protected from challenge with wild type B. melitensis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001400 .

obo:VO_0003727 a rdfs:Class ;
  rdfs:label "Afluria 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000006 , obo:VO_0000578 , obo:VO_0010433 .

obo:VO_0003251 a rdfs:Class ;
  rdfs:label "Flu-Imune vaccine" ;
  rdfs:comment "A trivalent inactive influenza virus vaccine." ;
  rdfs:subClassOf obo:VO_0001236 , obo:VO_0002495 .

obo:VO_0019486 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.265 MG/ML / hepatitis B surface antigen vaccine 0.01 MG/ML Injection [COMVAX]" ;
  rdfs:subClassOf obo:VO_0019482 , obo:VO_0019485 .

obo:VO_0002185 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis VG/GA Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 17V1.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0020197 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.025 MG/ML" ;
  rdfs:subClassOf obo:VO_0020497 .

obo:VO_0002774 a rdfs:Class ;
  rdfs:label "obsolete Actinobacillus pleuropneumoniae ureC and apxIIA double mutant deletion vaccine" ;
  rdfs:comment "Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application" .

obo:VO_0020519 a rdfs:Class ;
  rdfs:label "0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0020950 .

obo:VO_0001633 a rdfs:Class ;
  rdfs:label "Bursal Disease Killed Virus Vaccine (USDA: 1275.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000960 , obo:VO_0007748 .

obo:NCBITaxon_10258 a rdfs:Class ;
  rdfs:label "Orf virus" ;
  rdfs:subClassOf obo:NCBITaxon_10241 .

obo:VO_0004449 a rdfs:Class ;
  rdfs:label "Prostate cancer DNA vaccine psig-3P-Fc encoding 3P(hPSM, hPAP, or hPSA)-Fc fusion protein" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0000933 a rdfs:Class ;
  rdfs:label "E. coli CS3 in PLGA microspheres" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0003037 a rdfs:Class ;
  rdfs:label "lactose vaccine stabilizer" ;
  rdfs:comment "a vaccine stabilizer that is specifically made by a lactose." ;
  rdfs:subClassOf obo:VO_0003034 .

obo:VO_0018026 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 1000000 CELLS / poliovirus vaccine inactivated, type 2 (MEF-1) 100000 CELLS / poliovirus vaccine inactivated, type 3 (Saukett) 300000 CELLS Injectable Suspension [Polio Sabin-Rit Multi]" ;
  rdfs:subClassOf obo:VO_0018025 .

obo:VO_0020469 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003855 , obo:VO_0020278 .

obo:VO_0007676 a rdfs:Class ;
  rdfs:label "hyperacute-melanoma vaccine" ;
  rdfs:comment "A cancer vaccine composed of irradiated allogeneic melanoma cell lines (HAM-1, HAM-2 and HAM-3). These cell lines have been transduced with a recombinant Moloney murine leukemia virus (MoMLV)-based retroviral vector expressing the murine alpha(1,3)GT gene, a mouse gene that causes the production of a foreign pattern of protein-sugars on the cell surface. The immune response to the foreign substance could stimulate the immune system to attack the patient's own cancer cells that have similar proteins without this sugar pattern, causing the tumor to remain stable or shrink." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0021032 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0017233 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Tripacel]" ;
  rdfs:subClassOf obo:VO_0010742 , obo:VO_0017230 .

obo:VO_0010073 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi PFR Ag" ;
  rdfs:comment "A PFR Ag protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0002040 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotypes 1 & 2 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 1281.R0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0015533 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution [Gemvites]" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0000228 a rdfs:Class ;
  rdfs:label "vaccine powder" ;
  rdfs:comment "a vaccine component that contains the solid form of all vaccine components. A vaccine can be reconstituted by mixing vaccine powder with vaccine solvent." ;
  rdfs:subClassOf obo:VO_0000179 .

obo:VO_0000777 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum FMP1/AS02A vaccine" ;
  rdfs:comment "A recombinant E. coli-expressed protein based upon the apical membrane antigen-1 (AMA-1) of the 3D7 clone formulated with the AS02A adjuvant. PMID:17442466." ;
  rdfs:subClassOf obo:VO_0000087 .

obo:NCBITaxon_2871093 a rdfs:Class ;
  rdfs:label "tremovirus A1" ;
  rdfs:subClassOf obo:NCBITaxon_70796 .

obo:VO_0000843 a rdfs:Class ;
  rdfs:label "Feline leukemia virus vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0004600 a rdfs:Class ;
  rdfs:label "rBCG-SIVgag and rDIsSIVgag Prime-boost SHIV vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0002433 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Vaccine" ;
  rdfs:subClassOf obo:VO_0000389 , obo:VO_0000843 , obo:VO_0002440 .

obo:NCBITaxon_10571 a rdfs:Class ;
  rdfs:label "Bovine papillomavirus" ;
  rdfs:subClassOf obo:NCBITaxon_333774 .

obo:VO_0017473 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017472 , obo:VO_0017474 .

obo:VO_0007111 a rdfs:Class ;
  rdfs:label "synthetic melanoma-associated antigens vaccine" ;
  rdfs:comment "A cancer vaccine containing synthetic epitope peptides derived from melanoma tumor-associated antigens (TAAs), including melanoma-melanocyte antigen gp100(280-288), melanoma-associated antigen tyrosinase(1-9), and melanoma-associated antigen melan-A(27-35). Upon administration, synthetic melanoma-associated antigens vaccine may stimulate a cytotoxic T-lymphocyte immune response against melanoma cells that express TAAs which share epitopes with the vaccine epitope peptides, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0001441 a rdfs:Class ;
  rdfs:label "Porcine respiratory and reproductive syndrome virus gene" ;
  rdfs:comment "A viral gene that is from Porcine respiratory and reproductive syndrome virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0003823 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML [Flumist Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003820 .

obo:VO_0001967 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona-Mannheimia Haemolytica Bacterin (USDA: 4475.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002366 .

obo:VO_0004619 a rdfs:Class ;
  rdfs:label "rSPV-PCV2-cap vaccine" ;
  rdfs:subClassOf obo:VO_0001524 .

obo:VO_0020599 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Xanaflu]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020882 .

obo:VO_0015212 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0015211 .

obo:VO_0003090 a rdfs:Class ;
  rdfs:label "Tri-Immunol vaccine" ;
  rdfs:comment "This vaccine is given to provide protection against diphtheria, tetanus, and pertussis in children between 6 weeks and 7 years old." ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0011303 a rdfs:Class ;
  rdfs:label "FliC" ;
  rdfs:comment "Flagellin encoding plasmid DNA was injected into Balb/c mice intramuscularly and this elicited both a humoral and a cellular immune response. Subsequent intravenous challenge of the vaccinated Balb/c mice with 10^5CFU of B. pseudomallei resulted in the number of bacterial cells detected in liver and/or spleen being significantly reduced in the flagellin plasmid DNA vaccinated mice. At 7 days subsequent to infection of B. pseudomallei, 5/6 (83%) of flagellin plasmid DNA vaccinated mice had survived [PubMed: 16169637]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010840 .

obo:VO_0003535 a rdfs:Class ;
  rdfs:label "Gammaproteobacteria vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003531 .

obo:VO_0004836 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0015500 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003415 .

obo:VO_0002673 a rdfs:Class ;
  rdfs:label "obsolete aroD from Shigella" ;
  rdfs:comment "An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri" .

obo:VO_0016765 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0016718 .

obo:VO_0004211 a rdfs:Class ;
  rdfs:label "West Nile Virus DNA Vaccine (USDA: 1995.D0)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000752 , obo:VO_0007748 .

obo:VO_0019306 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Fluvirin 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019301 , obo:VO_0020473 .

obo:VO_0016992 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0016987 , obo:VO_0017479 .

obo:VO_0018582 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML Oral Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018578 , obo:VO_0018684 .

obo:VO_0020728 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0020723 .

obo:VO_0010144 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, subunit, recombinant spike protein-nanoparticle+Matrix-M1 Adjuvant, preservative free, 5 mcg/0.5 mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005267 , obo:VO_0005269 .

obo:VO_0010004 a rdfs:Class ;
  rdfs:label "obsolete Crptosporidium parvum Cp23" ;
  rdfs:comment "A Cp23 protein that is part of Crptosporidium parvum" .

obo:VO_0018426 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:VO_0003077 a rdfs:Class ;
  rdfs:label "obsolete RB51 induced protection against B. ovis" .

obo:VO_0018493 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 20 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0018459 .

obo:VO_0007065 a rdfs:Class ;
  rdfs:label "Synthetic Long E6/E7 Peptides Vaccine HPV-01" ;
  rdfs:comment "A therapeutic peptide vaccine consisting of thirteen synthetic long peptides (SLPs), which are 25-35 amino acids in size, derived from the human papillomavirus (HPV) type 16 oncoproteins E6 and E7, with potential immunostimulating and antitumor activities. Upon administration, synthetic long E6/E7 peptides vaccine HPV-01 is taken up and degraded into small pieces by dendritic cells. The processed viral epitopes are presented by dendritic cells, which may stimulate the host immune system to mount both cytotoxic T-cell lymphocyte (CTL) and helper T cell responses against HPV E6/E7-expressing tumor cells. This results in the destruction of tumor cells and leads to decreased tumor growth. The E6 and E7 oncoproteins are implicated in the tumorigenesis in a variety of cancers. The SLPs allow for optimal presentation by antigen-presenting cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005488 , obo:VO_0007657 .

obo:OBI_0302732 a rdfs:Class ;
  rdfs:label "solvent role"@en ;
  rdfs:comment "solvent role is a role which inheres in a molecular entity capable of ensuring the dissolution of another chemical entity and realized by the process of solvation"@en ;
  rdfs:subClassOf obo:OBI_0003610 .

obo:OGMS_0000060 a rdfs:Class ;
  rdfs:label "bodily process" ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0007003 a rdfs:Class ;
  rdfs:label "PEP-CMV Vaccine" ;
  rdfs:comment "A peptide vaccine derived from cytomegalovirus (CMV) antigens with potential immunostimulating activity. Intradermal administration of the PEP-CMV vaccine may stimulate the immune system to mount a specific helper and cytotoxic T-lymphocyte (CTL) response against CMV-infected tumor cells. Infection with the herpesvirus CMV may play a significant role in tumor cell initiation and progression as well as chemoresistance." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0000101 a rdfs:Class ;
  rdfs:label "vaccine-induced T-helper 2 type immune response" ;
  rdfs:comment "Th2 cells secrete IL-4, IL-5, IL-9, IL-10, and IL-13 and stimulate type 2 immunity, which is characterized by high antibody titers. https://academic.oup.com/cid/article/32/1/76/311106" ;
  rdfs:subClassOf obo:VO_0000106 .

obo:VO_0018849 a rdfs:Class ;
  rdfs:label "influenza A virus (H5N1) antigen" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0020491 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2020-2021 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010424 .

obo:VO_0020609 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 50 by Evans Vaccines" ;
  rdfs:subClassOf obo:VO_0020608 .

obo:VO_0017114 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017576 .

obo:VO_0015573 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites]" ;
  rdfs:subClassOf obo:VO_0015492 , obo:VO_0015533 .

obo:VO_0017870 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.25 MG" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0011382 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 DNA vaccine AdCMVgC" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000987 .

obo:VO_0017971 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0017941 , obo:VO_0017958 .

obo:VO_0004226 a rdfs:Class ;
  rdfs:label "BVDV Inactivated vaccine" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0001501 .

obo:VO_0017794 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 600 UNT/ML [Acel-P]" ;
  rdfs:subClassOf obo:VO_0017804 .

obo:VO_0003282 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML [Zostavax]" ;
  rdfs:subClassOf obo:VO_0003281 .

obo:VO_0010134 a rdfs:Class ;
  rdfs:label "host comorbidity variable" ;
  rdfs:comment "A variable representing host quality's that leads to a wore outcome to vaccination or pathogen disease state." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:UBERON_0002097 a rdfs:Class ;
  rdfs:label "skin of body" ;
  rdfs:comment "The organ covering the body that consists of the dermis and epidermis." ;
  rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0004121 .

obo:VO_0017787 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017779 .

obo:VO_0003988 a rdfs:Class ;
  rdfs:label "Adacel Injection" ;
  rdfs:subClassOf obo:VO_0003984 .

obo:VO_0020036 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020028 , obo:VO_0020478 .

obo:VO_0002146 a rdfs:Class ;
  rdfs:label "Marek's Disease-Tenosynovitis Serotypes 2 & 3, Live & Modified Live Virus Vaccine (USDA: 16T1.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001019 , obo:VO_0002448 , obo:VO_0007748 .

obo:VO_0002506 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda vaccine" ;
  rdfs:comment "An Edwardsiella bacterial vaccine that protects against Edwardsiella tarda." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000602 .

obo:VO_0001488 a rdfs:Class ;
  rdfs:label "Gallid herpesvirus 1 vaccine" ;
  rdfs:comment "Viral vaccine that is used to protect against Gallid herpesvirus 1 infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000727 .

obo:VO_0011450 a rdfs:Class ;
  rdfs:label "Entamoeba histolytica Eh29 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012171 .

obo:VO_0001099 a rdfs:Class ;
  rdfs:label "health-care and emergency medical services personnel" ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:VO_0020898 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Pandemrix]" ;
  rdfs:subClassOf obo:VO_0000410 , obo:VO_0020887 .

obo:VO_0019537 a rdfs:Class ;
  rdfs:label "human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML / human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018797 .

obo:VO_0016056 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 3" ;
  rdfs:subClassOf obo:VO_0003259 .

obo:VO_0020085 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain 158000000 UNT/ML Nasal Spray [FluMist 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020084 , obo:VO_0020347 .

obo:VO_0018798 a rdfs:Class ;
  rdfs:label "Human Papillomavirus 6/11/16/18 L1 virus vaccine" ;
  rdfs:subClassOf obo:VO_0000667 .

obo:VO_0002551 a rdfs:Class ;
  rdfs:label "aroA from Bordetella bronchiseptica" ;
  rdfs:comment "Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001407 .

obo:VO_0021145 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.04 MG/ML Prefilled Syringe [Gardasil]" ;
  rdfs:subClassOf obo:VO_0000049 .

obo:VO_0017689 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Covaxis] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017686 .

obo:VO_0010826 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0000860 a rdfs:Class ;
  rdfs:label "vaccine effectiveness" ;
  rdfs:comment "Vaccine effectiveness is an effectiveness associated with a vaccine." ;
  rdfs:subClassOf obo:VO_0000804 .

obo:VO_0010484 a rdfs:Class ;
  rdfs:label "licensed human immunodeficiency virus vaccine" ;
  rdfs:comment "Human immunodeficiency virus vaccine that is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000295 , obo:VO_0000635 .

obo:VO_0018343 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003335 .

obo:VO_0020947 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML Nasal Spray [FluMist Quadrivalent]" ;
  rdfs:subClassOf obo:VO_0020942 , obo:VO_0020946 .

obo:VO_0011490 a rdfs:Class ;
  rdfs:label "Coccidioides posadasii subunit GEL1 protein vaccine" ;
  rdfs:comment "a Coccidioides vaccine that contains C. posadasii subunit GEL1 protein" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012179 .

obo:VO_0001450 a rdfs:Class ;
  rdfs:label "Leishmania donovani gene" ;
  rdfs:comment "A protozoan gene that is from Leishmania donovani." ;
  rdfs:subClassOf obo:VO_0000174 .

obo:VO_0002660 a rdfs:Class ;
  rdfs:label "spoT from Salmonella Gallinarum" ;
  rdfs:comment "A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001420 .

obo:VO_0003877 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML [Flublok 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003874 , obo:VO_0004914 .

obo:VO_0012372 a rdfs:Class ;
  rdfs:label "PPE31" ;
  rdfs:comment "A selection of previously identified protective Mycobacterium tuberculosis DNA vaccines were re-formulated as proteins and administered with a Th1-inducing adjuvant to help stimulate the relevant immune responses necessary for protection. One candidate (Rv1806-1807) induced protection in the guinea pig aerosol infection model 30 days post-challenge on the basis of reducing the bacterial burden of M. tuberculosis in the lungs [PubMed: 16520093]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0018324 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0018295 , obo:VO_0018311 .

obo:VO_0015824 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] by Sanofi" ;
  rdfs:subClassOf obo:VO_0015619 .

obo:VO_0001033 a rdfs:Class ;
  rdfs:label "Babesia bigemina vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 , obo:VO_0001466 .

obo:VO_0007126 a rdfs:Class ;
  rdfs:label "Unconjugated Myeloma Ig Id Vaccine" ;
  rdfs:comment "A vaccine consisting of myeloma-specific immunoglobulin that is not conjugated to a carrier molecule. Vaccination with unconjugated myeloma Ig Id may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against myeloma cells, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0021047 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0020191 a rdfs:Class ;
  rdfs:label "rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML Injectable Solution [Meruvax II]" ;
  rdfs:subClassOf obo:VO_0020190 , obo:VO_0020192 .

obo:VO_0020288 a rdfs:Class ;
  rdfs:label "varicella-zoster virus vaccine live (Oka-Merck) strain 29800 UNT/ML Injection [Zostavax]" ;
  rdfs:subClassOf obo:VO_0000124 , obo:VO_0020287 .

<http://www.w3.org/2003/11/swrl#Variable> a rdfs:Class .

obo:VO_0020665 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution Box of 3" ;
  rdfs:subClassOf obo:VO_0020656 , obo:VO_0020707 .

obo:VO_0005388 a rdfs:Class ;
  rdfs:label "SWE vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002541 a rdfs:Class ;
  rdfs:label "proC from Mycobacterium tuberculosis" ;
  rdfs:comment "A proC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis that is equal to the protection induced by the current vaccine BCG" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0019556 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flucelvax Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003791 , obo:VO_0019544 .

obo:VO_0010278 a rdfs:Class ;
  rdfs:label "assay platform datum" ;
  rdfs:comment "A measurment datum that records the type of platform used for an assay." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0007119 a rdfs:Class ;
  rdfs:label "vaccinia melanoma cell lysates (VMCL) vaccine" ;
  rdfs:comment "A cancer vaccine with VMCL was not associated with a statistically significant improvement in OS or RFS, with CIs not ruling out important gains from such treatment." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0003771 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2017-2018 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003768 .

obo:VO_0007323 a rdfs:Class ;
  rdfs:label "alk peptide vaccine" ;
  rdfs:comment "A cancer vaccine that restored priming of Anaplastic lymphoma kinase (ALK)-specific CD8+ T cells, eradicated lung tumors in combination with ALK tyrosine kinase inhibitors (TKIs) and prevented metastatic dissemination of tumors to the brain. Human ALK peptides are displayed by HLA-A*02:01 and HLA-B*07:02 molecules. The peptides are immunogenic and recognized by CD8+ T cells from individuals with non-small cell lung cancer (NSCLC)." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0003140 , obo:VO_0007657 .

obo:VO_0015030 a rdfs:Class ;
  rdfs:label "Varivax Injectable Product" ;
  rdfs:subClassOf obo:VO_0000119 .

obo:NCBITaxon_10937 a rdfs:Class ;
  rdfs:label "Equine rotavirus" ;
  rdfs:subClassOf obo:NCBITaxon_10912 .

obo:VO_0007545 a rdfs:Class ;
  rdfs:label "MVA-EBNA1/LMP2 Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the gene for the CD4 epitope-rich C-terminal domain of the Epstein Barr Virus (EBV) antigen EBNA1 and fused to the full-length of the EBV-associated antigen latent membrane protein 2 (LMP2), with potential immunostimulatory and antineoplastic activities. Upon administration, MVA EBNA1/LMP2 vaccine may elicit a cytotoxic T-cell immune response against cancer cells expressing EBNA1 and LMP2. Multi-antigen vaccine therapy may be more efficacious than single-antigen therapy vaccine therapy. EBNA1, a sequence-specific DNA binding protein, plays an important role in EBV episomal genome maintenance and gene transactivation. (NCIT_C91076)." ;
  rdfs:subClassOf obo:VO_0005498 , obo:VO_0007657 .

obo:NCBITaxon_2790996 a rdfs:Class ;
  rdfs:label "Mycoplasmoidales" ;
  rdfs:subClassOf obo:NCBITaxon_544448 .

obo:VO_0002087 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12P5.41)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002384 , obo:VO_0007748 .

obo:VO_0002756 a rdfs:Class ;
  rdfs:label "HSP70 II from Leishmania infantum" ;
  rdfs:comment "A Leishmania infantum deletion mutant of HSP70-II gene is attenuated and provides protection against Leishmania infection in the L. major-BALB/c infection model. Also, DeltaHSP70-II is a safe live vaccine as immunodeficient SCID mice, and hamsters, infected with mutant parasites did not develp any sign of pathology" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0002515 .

obo:VO_0011371 a rdfs:Class ;
  rdfs:label "Cancer VEGFA protein vaccine" ;
  rdfs:comment "Gene name: VEGFA" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0018571 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension [Stamaril]" ;
  rdfs:subClassOf obo:VO_0018570 , obo:VO_0018762 .

obo:VO_0010957 a rdfs:Class ;
  rdfs:label "Pvs25" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015473 .

obo:VO_0005352 a rdfs:Class ;
  rdfs:label "VLPCOV-01 vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine manufactured by VLP Therapeutics Japan, LLC" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0003509 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0003507 .

obo:VO_0020506 a rdfs:Class ;
  rdfs:label "Rickettsia prowazekii as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0016754 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Infanrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0016715 , obo:VO_0016779 .

obo:VO_0004857 a rdfs:Class ;
  rdfs:label "ACAM2000 smallpox (vaccinia) vaccine, live Injectable Solution" ;
  rdfs:subClassOf obo:VO_0004856 .

obo:VO_0019802 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML Injection [Flublok 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003894 , obo:VO_0019801 .

obo:BFO_0000141 a rdfs:Class ;
  rdfs:label "immaterial entity"@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:VO_0018733 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 2000000000 ORGANISMS [Vivotif Berna]" ;
  rdfs:subClassOf obo:VO_0018732 .

obo:VO_0018740 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 8 X Oral Tablet" ;
  rdfs:subClassOf obo:VO_0018739 .

obo:VO_0007606 a rdfs:Class ;
  rdfs:label "GM-CSF transfected cells vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0017783 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0017780 , obo:VO_0017787 .

obo:VO_0017777 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010435 .

obo:VO_0010340 a rdfs:Class ;
  rdfs:label "CAPVAXIVE vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000424 , obo:VO_0000556 .

obo:VO_0007007 a rdfs:Class ;
  rdfs:label "Synthetic Glioblastoma Tumor-associated Peptides Vaccine Therapy APVAC1" ;
  rdfs:comment "A personalized peptide-based cancer vaccine comprised of five to ten peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB tumor-associated peptides vaccine therapy APVAC1 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the tumor associated peptides, and results in decreased GB growth. The peptides are derived from a glioma actively-personalized vaccine consortium (GAPVAC) warehouse and are specifically selected based on the patient's expression of tumor-associated antigens." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0000134 a rdfs:Class ;
  rdfs:label "vaccine-induced T cell proliferation" ;
  rdfs:subClassOf obo:VO_0000115 .

obo:VO_0002630 a rdfs:Class ;
  rdfs:label "cya from Salmonella Typhimurium" ;
  rdfs:comment "A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0015522 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN Injectable Suspension [Engerix B]" ;
  rdfs:subClassOf obo:VO_0010711 , obo:VO_0015526 .

obo:VO_0001810 a rdfs:Class ;
  rdfs:label "swine influenza pH1N1, killed virus vaccine (USDA: 19A5.2P)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0007259 a rdfs:Class ;
  rdfs:label "anti-CTLA4 MoAb RNA-transfected autologous dendritic cell vaccine" ;
  rdfs:comment "An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. Anti-CTLA4 MoAb RNA-transfected autologous DC vaccine is prepared by transfecting DCs with RNAs encoding humanized heavy and light chains of the anti-CTLA4 (cytotoxic T-Lymphocyte-Associated Antigen 4); expression of anti-CTLA4 blocks the inhibitory effect of CTLA4 on the activation of T-lymphocytes. Co-vaccination of this vaccine with melanoma antigen specific vaccine may eliminate the adverse effects associated with systemic administration of immune modulators, while also enhancing vaccine-induced immune responses" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0020412 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0020389 , obo:VO_0020398 .

obo:VO_0020736 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain Injectable Solution [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020735 .

obo:VO_0017462 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0010467 a rdfs:Class ;
  rdfs:label "general correlate of immune protection" ;
  rdfs:comment "Correlated profile of immune protection that reliably predicts vaccine efficacy across settings different from those studied in an efficacy trial." ;
  rdfs:subClassOf obo:VO_0010465 .

obo:VO_0015511 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Gemvites]" ;
  rdfs:subClassOf obo:VO_0003256 .

obo:NCBITaxon_2732541 a rdfs:Class ;
  rdfs:label "Reovirales" ;
  rdfs:subClassOf obo:NCBITaxon_2732396 .

obo:NCBITaxon_12110 a rdfs:Class ;
  rdfs:label "Foot-and-mouth disease virus" ;
  rdfs:subClassOf obo:NCBITaxon_12058 .

obo:VO_0006027 a rdfs:Class ;
  rdfs:label "Junin virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Mammarenavirus juninense." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000455 , obo:VO_0000609 .

obo:VO_0016072 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015868 .

obo:VO_0011556 a rdfs:Class ;
  rdfs:label "Vivotif L vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000768 .

obo:VO_0000915 a rdfs:Class ;
  rdfs:label "gelatin vaccine allergen" ;
  rdfs:subClassOf obo:VO_0000910 .

obo:VO_0017222 a rdfs:Class ;
  rdfs:label "7.5 ML tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017219 , obo:VO_0017474 .

obo:VO_0001730 a rdfs:Class ;
  rdfs:label "Tenosynovitis Live Virus Vaccine (USDA: 1951.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001019 , obo:VO_0007748 .

obo:VO_0001905 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 43S5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002347 .

obo:VO_0010764 a rdfs:Class ;
  rdfs:label "Variola virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0005298 a rdfs:Class ;
  rdfs:label "BECC438b vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0001861 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D8.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0002436 , obo:VO_0007748 .

obo:VO_0003114 a rdfs:Class ;
  rdfs:label "Trihibit vaccine" ;
  rdfs:comment "A vaccine for Diphtheria, haemophilus influenzae, pertussis, and tetanus diseases." ;
  rdfs:subClassOf obo:VO_0003168 .

obo:VO_0015562 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015536 , obo:VO_0015594 .

obo:VO_0005131 a rdfs:Class ;
  rdfs:label "VRP-SARS-N vaccine" ;
  rdfs:comment "A SARS recombinant vector vaccine made from Venezuelan equine encephalitis replicons (VRP) encoding a SARS-CoV CD4+ T cell epitope vaccinated intranasally. Crosslisted as MERS vaccine (VIOLINID:5789). Efficacy higher intranasally than subcutaneously." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0012183 .

obo:VO_0017205 a rdfs:Class ;
  rdfs:label "1 ML tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017533 .

obo:VO_0018729 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0018724 .

obo:VO_0015119 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015111 .

obo:VO_0000854 a rdfs:Class ;
  rdfs:label "vaccine residual" ;
  rdfs:comment "A vaccine component that remains from the vaccine manufacturing process." ;
  rdfs:subClassOf obo:VO_0000179 .

obo:VO_0020794 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 CELLS" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0019465 .

obo:VO_0018099 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Prefilled Syringe [Priorix]" ;
  rdfs:subClassOf obo:VO_0018098 , obo:VO_0018234 .

obo:NCBITaxon_111105 a rdfs:Class ;
  rdfs:label "Porphyromonas gulae" ;
  rdfs:subClassOf obo:NCBITaxon_836 .

obo:VO_0016370 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0019848 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML [Fluarix Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0020322 .

obo:VO_0001318 a rdfs:Class ;
  rdfs:label "CRL1005 vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is a copolymer (CRL1005), based on a 12 kDa polyoxypropylene (POP) core with 5% POE." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0005370 a rdfs:Class ;
  rdfs:label "glycerol vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that includes naturally occurring trivalent alcohol." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0015044 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 45 Vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003306 .

obo:VO_0002271 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4875.23)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000539 , obo:VO_0000640 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0015096 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Epaxal] Box of 1" ;
  rdfs:subClassOf obo:VO_0015095 , obo:VO_0015103 , obo:VO_0015254 .

obo:VO_0001483 a rdfs:Class ;
  rdfs:label "Borna disease virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Borna disease virus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0001376 a rdfs:Class ;
  rdfs:label "vaccinated" ;
  rdfs:comment "an organismal quality that indicates an organism (e.g., human) is vaccinated with a vaccine." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:VO_0021159 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML Injection [Menquadfi]" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0019160 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Quadracel]" ;
  rdfs:subClassOf obo:VO_0000744 , obo:VO_0010437 , obo:VO_0010736 , obo:VO_0020832 .

obo:VO_0003330 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 4 vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003232 .

obo:VO_0010771 a rdfs:Class ;
  rdfs:label "Plasmodium spp. protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0016041 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0015669 , obo:VO_0015796 .

obo:CHEBI_37586 a rdfs:Class ;
  rdfs:label "sodium phosphate" ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0007219 a rdfs:Class ;
  rdfs:label "Allogeneic Cellular Vaccine 1650-G" ;
  rdfs:comment "A pluripotent, allogeneic, tumor cell vaccine composed of irradiated tumor cells from the non-small cell lung cancer (NSCLC) cell line 1650 and the immunoadjuvant recombinant granulocyte-macrophage colony stimulating factor (GM-CSF) (1650-G), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic cellular vaccine 1650-G may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against tumor-associated antigens (TAAs) expressed on NSCLC cells. GM-CSF potentiates the antitumor immune response. The 1650 cell line is used as a source for TAAs." ;
  rdfs:subClassOf obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0007654 a rdfs:Class ;
  rdfs:label "HPV infection" ;
  rdfs:comment "An infection that has as part organisms of the human papillomavirus (HPV)." ;
  rdfs:subClassOf obo:IDO_0000586 .

obo:VO_0003260 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010306 , obo:VO_0010415 .

obo:VO_0015289 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015286 .

obo:VO_0001554 a rdfs:Class ;
  rdfs:label "Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0007748 .

obo:VO_0019526 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.01 MG/ML Prefilled Syringe [Recombivax]" ;
  rdfs:subClassOf obo:VO_0015491 .

obo:VO_0002671 a rdfs:Class ;
  rdfs:label "obsolete aroA from Shigella" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" .

obo:VO_0007274 a rdfs:Class ;
  rdfs:label "AUT-OV-ALVAC-hB7.1 Vaccine" ;
  rdfs:comment "A vaccine comprised of autologous epithelial ovarian cells infected with ALVAC-hB7.1" ;
  rdfs:subClassOf obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0017624 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetasorbat]" ;
  rdfs:subClassOf obo:VO_0017594 , obo:VO_0017610 .

obo:VO_0020411 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typherix]" ;
  rdfs:subClassOf obo:VO_0020393 .

obo:VO_0019680 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2016 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020488 .

obo:VO_0020859 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluarix] Box of 10" ;
  rdfs:subClassOf obo:VO_0020858 , obo:VO_0020884 .

obo:VO_0015335 a rdfs:Class ;
  rdfs:label "hepatitis A virus / typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 , obo:VO_0010451 , obo:VO_0015322 .

obo:CL_0000518 a rdfs:Class ;
  rdfs:label "phagocyte (sensu Vertebrata)" ;
  rdfs:comment "A phagocyte in vertebrates that is able to phagocytosis." ;
  rdfs:subClassOf obo:CL_0000234 , obo:CL_0000255 .

obo:VO_0004814 a rdfs:Class ;
  rdfs:label "Biothrax 0.5 ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0004218 .

obo:VO_0002867 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium asd mutant vaccine" ;
  rdfs:comment "An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0003863 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003862 .

obo:VO_0007115 a rdfs:Class ;
  rdfs:label "TRP-2: 180-188 peptide vaccine" ;
  rdfs:comment "A recombinant peptide consisting of amino acid residues 180 to 188 of the tyrosinase-related protein 2 (TRP2). Expressed by cells of melanocyte origin, TRP2 is an enzyme involved in the process that converts tyrosinase to melanin pigments. Vaccination with TRP-2: 180-188 peptide may induce cytotoxic T lymphocyte (CTL) responses to melanoma cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0000291 a rdfs:Class ;
  rdfs:label "host response to vaccine antigen" ;
  rdfs:comment "a process that specifies host response to a vaccine antigen." ;
  rdfs:subClassOf obo:VO_0000290 .

obo:VO_0018332 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 5 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0018319 .

obo:DOID_219 a rdfs:Class ;
  rdfs:label "colon cancer"@en ;
  rdfs:comment "A colorectal cancer that is located_in the colon."@en ;
  rdfs:subClassOf obo:DOID_9256 .

obo:VO_0000370 a rdfs:Class ;
  rdfs:label "live virulent vaccine" ;
  rdfs:comment "Vaccine that uses a live, pathogenic (disease-causing) microorganism to stimulate the immune system." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:VO_0003569 a rdfs:Class ;
  rdfs:label "Prevnar 13 Injectable Product" ;
  rdfs:subClassOf obo:VO_0001244 .

obo:VO_0002387 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-GrippotyphosaIcterohaemorrhagiae-Pomona Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0002388 .

obo:VO_0002470 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Vaccine-Escherichia Coli Bacterin" ;
  rdfs:subClassOf obo:VO_0001505 , obo:VO_0002474 .

obo:VO_0015201 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015200 .

obo:VO_0006106 a rdfs:Class ;
  rdfs:label "ACM-CpG vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant that targets on TLR-agonist. It is a nucleic acid-based adjuvant for chemical nature." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:NCBITaxon_560210 a rdfs:Class ;
  rdfs:label "Dintheria" ;
  rdfs:subClassOf obo:NCBITaxon_119088 .

obo:VO_0020865 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippeimpfstoff Ratiopharm]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020894 .

obo:VO_0006050 a rdfs:Class ;
  rdfs:label "rotavirus vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010449 .

obo:VO_0000986 a rdfs:Class ;
  rdfs:label "obsolete avian influenza vaccine" .

obo:VO_0000755 a rdfs:Class ;
  rdfs:label "edible vaccine" ;
  rdfs:comment "A vaccine that is edible and derived from an edible plant. The transgenic plant is used as recombinant protein production system. The edible plant tissue functions as an oral vaccine." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0020870 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Influsplit] Box of 10" ;
  rdfs:subClassOf obo:VO_0020869 , obo:VO_0020884 .

obo:VO_0018856 a rdfs:Class ;
  rdfs:label "influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010301 , obo:VO_0010415 .

obo:VO_0002078 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Killed Virus Vaccine (USDA: 12M5.40)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0002135 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live Virus; Canarypox Vector Vaccine (USDA: 1591.R1)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002395 , obo:VO_0007748 .

obo:VO_0001022 a rdfs:Class ;
  rdfs:label "Megan Vac1 vaccine" ;
  rdfs:comment "Megan Vac1 is a Salmoneela vaccine that consists of a double gene-deleted S. enterica serovar Typhimurium strain and is designed for protection of broilers to reduce Salmonella contamination." ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000768 .

obo:VO_0002195 a rdfs:Class ;
  rdfs:label "Porcine Circovirus Type 1 - Type 2 Chimera, Killed Virus Vaccine (USDA: 19K5.R1)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001524 , obo:VO_0007748 .

obo:VO_0007490 a rdfs:Class ;
  rdfs:label "gp100: ES209-217(210M) Peptide vaccine" ;
  rdfs:comment "A synthetic peptide vaccine consisting of amino acids 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen with an endoplasmic reticulum signal sequence (ES) to increase binding activity. Vaccination with gp100:ES209-217(210M) may stimulate the host immune system to mount a cytotoxic T lymphocyte response against tumor cells positive for gp100, resulting in decreased tumor growth" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0002745 a rdfs:Class ;
  rdfs:label "C protein from Tick-borne Encephalitis Virus" ;
  rdfs:comment "A virus with a mutation in protein C is attenuated in mice and induced protection from challenge with wild type TBE virus" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001446 .

obo:VO_0001902 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine (USDA: 1155.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0002345 .

obo:VO_0017703 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017696 .

obo:VO_0017993 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injectable Solution [Ipol]" ;
  rdfs:subClassOf obo:VO_0017992 , obo:VO_0018034 .

obo:OBI_0000938 a rdfs:Class ;
  rdfs:label "categorical measurement datum" ;
  rdfs:comment "A measurement datum that is reported on a categorical scale."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OPL_0000369 a rdfs:Class ;
  rdfs:label "Canis lupus familiaris erythrocyte" ;
  rdfs:comment "An erythrocyte that is a part of or originated from a Canis lupus familiaris." ;
  rdfs:subClassOf obo:CL_0000232 , obo:OPL_0000311 .

obo:VO_0015849 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] by Waymade" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 .

obo:VO_0004192 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus DNA vaccine encoding PBP2a Protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002502 .

obo:VO_0019400 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.936 UNT/ML / diphtheria toxoid vaccine, inactivated 13.4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017799 , obo:VO_0018770 .

obo:CL_0000738 a rdfs:Class ;
  rdfs:label "leukocyte" ;
  rdfs:comment "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ;
  rdfs:subClassOf obo:CL_0000219 , obo:CL_0000255 , obo:CL_0000988 , obo:CL_0002242 .

obo:NCBITaxon_2732406 a rdfs:Class ;
  rdfs:label "Kitrinoviricota" ;
  rdfs:subClassOf obo:NCBITaxon_2732396 .

obo:VO_0002124 a rdfs:Class ;
  rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002393 , obo:VO_0007748 .

obo:VO_0007177 a rdfs:Class ;
  rdfs:label "VHL14 Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL14 peptide is a point mutation variant of the VHL protein; the mutation is in amino acid position 166. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0018448 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 10" ;
  rdfs:subClassOf obo:VO_0018425 .

obo:VO_0002302 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.24)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002479 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0001183 a rdfs:Class ;
  rdfs:label "GonaCon vaccine" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000655 , obo:VO_0000759 .

obo:VO_0000013 a rdfs:Class ;
  rdfs:label "Bacillus anthracis vaccine" ;
  rdfs:comment "A vaccine that protects against Bacillus anthrax that causes anthrax." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003536 .

obo:VO_0016342 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:VO_0011305 a rdfs:Class ;
  rdfs:label "E2 from Western equine encephalomyelitis virus" ;
  rdfs:comment "This report describes the successful cloning of the E2 gene of WEEV and expression in Escherichia coli as inclusion bodies.  The immunogenicity of the refolded rE2 protein was demonstrated by strong humoral and cell mediated immune (CMI) responses in rE2-immunized BALB/c mice. The current study also demonstrated that rE2-immunized mice could be partially protected from lethal challenge of WEEV [PubMed: 17499379]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010841 .

obo:VO_0016787 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Pur] by Novartis" ;
  rdfs:subClassOf obo:VO_0016728 .

obo:VO_0000601 a rdfs:Class ;
  rdfs:label "Yersinia vaccine" ;
  rdfs:comment "Vaccine that protects against Yersinia bacterial infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003533 .

obo:NCBITaxon_636 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda" ;
  rdfs:subClassOf obo:NCBITaxon_635 .

obo:VO_0010938 a rdfs:Class ;
  rdfs:label "StxB2" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0002639 a rdfs:Class ;
  rdfs:label "guaB from Salmonella Enteritidis" ;
  rdfs:comment "A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001422 .

obo:VO_0001393 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi vaccine using attenuated Salmonella expressing Trypanosoma cruzi Cruzipain" ;
  rdfs:comment "A T. cruzi vaccine that uses attenuated Salmonella to express T. cruzi Cruzipain protein." ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0001385 .

obo:VO_0020642 a rdfs:Class ;
  rdfs:label "1 ML BCG, live, Connaught strain 20000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020715 .

obo:VO_0001123 a rdfs:Class ;
  rdfs:label "RECOMBITEK Canine Parvo vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000649 , obo:VO_0012180 .

obo:VO_0020224 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (BA.4/BA.5) 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0020498 .

obo:VO_0021006 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 UNT Injection [Varivax] by Merck" ;
  rdfs:subClassOf obo:VO_0021005 .

obo:VO_0010950 a rdfs:Class ;
  rdfs:label "SecA2" ;
  rdfs:comment "Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Gurin vaccination [PubMed: 17671656]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:NCBITaxon_1506574 a rdfs:Class ;
  rdfs:label "Protoparvovirus" ;
  rdfs:subClassOf obo:NCBITaxon_40119 .

obo:VO_0010748 a rdfs:Class ;
  rdfs:label "Vivaxim vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000950 , obo:VO_0010438 , obo:VO_0010451 .

obo:VO_0002404 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0001526 , obo:VO_0002405 .

obo:VO_0019247 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019774 .

obo:VO_0000874 a rdfs:Class ;
  rdfs:label "Anthrax Spore vaccine" ;
  rdfs:comment "Anthrax Spore Vaccine is a B. anthracis vaccine that is prepared with a relatively nonpathogenic, noncapsulated variant strain of B. anthracis, originally developed at the Onderstepoort Laboratory, Pretoria, South Africa. Further work was conducted in England, India and in many other countries. Vaccine Strain is Sterne 34F2. The vaccine is a suspension of viable Bacillus anthracis spores in saponin." ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000206 , obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000643 .

obo:DOID_1612 a rdfs:Class ;
  rdfs:label "breast cancer"@en ;
  rdfs:comment "An organ system cancer that originates in the mammary gland."@en ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_7 .

obo:VO_0021148 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.12 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 31 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 33 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 45 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 52 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 58 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.06 MG/ML Injection [Gardasil 9]" ;
  rdfs:subClassOf obo:VO_0003075 .

obo:VO_0003409 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003410 , obo:VO_0020832 .

obo:VO_0007145 a rdfs:Class ;
  rdfs:label "Prostate cancer DNA vaccine pDOM-PSMA27 encoding PSMA" ;
  rdfs:comment "This DNA vaccine expressed prostate-specific membrane antigen (PSMA)" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0018282 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injection [Verorab]" ;
  rdfs:subClassOf obo:VO_0018806 .

obo:VO_0003228 a rdfs:Class ;
  rdfs:label "obsolete 1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection [Recombivax]" .

obo:VO_0018900 a rdfs:Class ;
  rdfs:label "influenza A virus A/Victoria/1/2020 (H1N1) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0010095 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA23" ;
  rdfs:comment "A GRA23 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0010819 a rdfs:Class ;
  rdfs:label "Mycoplasma gallisepticum protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0019855 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Washington/19/2020 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020334 .

obo:VO_0018567 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0018730 .

obo:VO_0016146 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015886 .

obo:VO_0019130 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2021 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020492 .

obo:VO_0004266 a rdfs:Class ;
  rdfs:label "LEISH-F1+MPL-SE vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001142 .

obo:VO_0011516 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine BV-G-E" ;
  rdfs:subClassOf obo:VO_0000665 .

obo:VO_0020263 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003400 .

obo:VO_0010235 a rdfs:Class ;
  rdfs:label "vaccination-challenge interval variable" ;
  rdfs:comment "A variable representing the interval between vaccination and pathogen challenge" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:NCBITaxon_10293 a rdfs:Class ;
  rdfs:label "Alphaherpesvirinae" ;
  rdfs:subClassOf obo:NCBITaxon_3044472 .

obo:VO_0019661 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML [Fluzone Quadrivalent 2020 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020490 .

obo:VO_0015150 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015149 , obo:VO_0015174 , obo:VO_0015239 .

obo:VO_0000628 a rdfs:Class ;
  rdfs:label "E. coli subunit vaccine" ;
  rdfs:comment "An E. coli vaccine that uses subunit antigen type." ;
  rdfs:subClassOf obo:VO_0000041 , obo:VO_0000534 .

obo:VO_0005810 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA17 mutant vaccine" ;
  rdfs:comment "A Live attenuated vaccine with GRA17 mutant that immunizes against Toxoplasma gondii trypmastigote." ;
  rdfs:subClassOf obo:VO_0000994 .

obo:VO_0003564 a rdfs:Class ;
  rdfs:label "Pneumovax 23 Injection" ;
  rdfs:subClassOf obo:VO_0003563 .

obo:VO_0003233 a rdfs:Class ;
  rdfs:label "obsolete 1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection" .

obo:NCBITaxon_10497 a rdfs:Class ;
  rdfs:label "African swine fever virus" ;
  rdfs:subClassOf obo:NCBITaxon_2732525 .

obo:VO_0005449 a rdfs:Class ;
  rdfs:label "licensed human Rho(D) immune globulin - IM passive vaccine" ;
  rdfs:subClassOf obo:VO_0005451 .

obo:VO_0000473 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae rLP4/rLP6 and Moraxella catarrhalis UspA2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000471 .

obo:VO_0003299 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus vaccine" ;
  rdfs:subClassOf obo:VO_0000667 .

obo:VO_0002332 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000768 , obo:VO_0002331 .

obo:VO_0012394 a rdfs:Class ;
  rdfs:label "SfbI" ;
  rdfs:comment "Intranasal immunization of mice with either SfbI alone or coupled to cholera toxin B subunit (CTB) triggered efficient SfbI-specific humoral (mainly IgG) and lung mucosal (14% of total IgA) responses. SfbI-vaccinated animals showed 80% and 90% protection against homologous and heterologous challenge, respectively [PubMed: 10068585]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012357 .

obo:VO_0002261 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4847.32)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000542 , obo:VO_0000640 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0007748 .

obo:NCBITaxon_418101 a rdfs:Class ;
  rdfs:label "Plasmodium (Vinckeia)" ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0004208 a rdfs:Class ;
  rdfs:label "BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS" ;
  rdfs:comment "RXAUI: 5068281" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0016201 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Mtk" ;
  rdfs:subClassOf obo:VO_0015902 .

obo:VO_0002499 a rdfs:Class ;
  rdfs:label "influenza A (H1N1) 2009 monovalent vaccine (IDB)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003211 , obo:VO_0010415 .

obo:VO_0004701 a rdfs:Class ;
  rdfs:label "Typhi strain Ty21a-LPS-Shigella" ;
  rdfs:subClassOf obo:VO_0000769 .

obo:VO_0017700 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017699 .

obo:VO_0003691 a rdfs:Class ;
  rdfs:label "Fluvirin 2017-2018 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003688 .

obo:VO_0020058 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Injectable Suspension [Flulaval 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020337 .

obo:VO_0020687 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML [IMMUGRIP]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:OPL_0000276 a rdfs:Class ;
  rdfs:label "Plasmodium erythrocytic schizont" ;
  rdfs:comment "A Plasmodium schizont that is found in infected erythrocytes of a vertebrate host." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000275 .

obo:VO_0000123 a rdfs:Class ;
  rdfs:label "yellow fever virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Yellow fever virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003546 .

obo:VO_0015630 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [Hevac B]" ;
  rdfs:subClassOf obo:VO_0015564 , obo:VO_0015666 .

obo:NCBITaxon_2157 a rdfs:Class ;
  rdfs:label "Archaea" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:VO_0003341 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:NCBITaxon_2501931 a rdfs:Class ;
  rdfs:label "Orthocoronavirinae" ;
  rdfs:subClassOf obo:NCBITaxon_11118 .

obo:VO_0020353 a rdfs:Class ;
  rdfs:label "FluMist Quadrivalent 2021-2022 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000982 , obo:VO_0010423 .

obo:VO_0003575 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 10A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 11A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 12F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 14 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 15B vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 17F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 18C vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 19A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 19F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 2 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 20 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 22F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 23F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 3 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 33F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 4 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 5 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 6B vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 7F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 8 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 9N vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 9V vaccine 0.05 MG/ML [Pneumovax 23]" ;
  rdfs:subClassOf obo:VO_0000088 .

obo:VO_0018219 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT / Varicella Virus Vaccine Live (Oka-Merck) strain 1000 UNT Injectable Solution [Priorix-Tetra] by GSK" ;
  rdfs:subClassOf obo:VO_0018218 .

obo:VO_0004741 a rdfs:Class ;
  rdfs:label "ALVAC-MV-HA/F vaccine" ;
  rdfs:subClassOf obo:VO_0000654 .

obo:VO_0017714 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017713 , obo:VO_0017780 .

obo:VO_0002778 a rdfs:Class ;
  rdfs:label "obsolete Listeria monocytogenes actA/plcB mutant vaccine" ;
  rdfs:comment "A plcB mutant, in combination with an actA mutant, is attenuated in mice and induces significant protection from challenge with wild type L. monocytogenes" .

obo:VO_0004283 a rdfs:Class ;
  rdfs:label "Brucella abortus S19 vjbR mutant vaccine" ;
  rdfs:subClassOf obo:VO_0000108 .

obo:VO_0019509 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0018870 , obo:VO_0019508 , obo:VO_0019513 .

obo:VO_0002425 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ;
  rdfs:subClassOf obo:VO_0001526 , obo:VO_0002397 .

obo:VO_0004636 a rdfs:Class ;
  rdfs:label "rSPV-HA1 (Swine influenza virus H1N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0004321 a rdfs:Class ;
  rdfs:label "IHNV DNA vaccine pCMV4-G" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012165 .

obo:VO_0017367 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution [Revaxis]" ;
  rdfs:subClassOf obo:VO_0003095 , obo:VO_0017366 .

obo:VO_0017346 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017344 .

obo:VO_0015012 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML" ;
  rdfs:subClassOf obo:VO_0015013 .

obo:VO_0018867 a rdfs:Class ;
  rdfs:label "influenza A virus A/Switzerland/3330/2017 (H1N1) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0003460 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine, Inactivated 50 UNT/ML Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0003465 .

obo:VO_0001415 a rdfs:Class ;
  rdfs:label "Mannheimia haemolytica gene" ;
  rdfs:comment "A bacterial gene that is from Mannheimia haemolytica." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0000730 a rdfs:Class ;
  rdfs:label "obsolete Marek disease vaccine" .

obo:VO_0015128 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe [Epaxal] Box of 1" ;
  rdfs:subClassOf obo:VO_0015127 , obo:VO_0015131 , obo:VO_0015294 .

obo:VO_0007104 a rdfs:Class ;
  rdfs:label "recombinant Vaccinia-Mgp100 vaccine" ;
  rdfs:comment "A recombinant vaccinia virus encoding a modified peptide of the gp100 melanoma-melanocyte antigen with potential use in cancer immunotherapy. gp100 human antigen is a wild type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas. This recombinant vaccinia Mgp100 encodes a fragment epitope of gp100 bearing 2 amino acids substitution; T->M at position 210 and 288 A ->V at position 210. This modification may stimulate tumor infiltrating lymphocytes (TIL) more efficiently." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0001890 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.31)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002338 .

obo:VO_0000549 a rdfs:Class ;
  rdfs:label "bacterial phenotype" ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:VO_0016962 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension by Sanofi" ;
  rdfs:subClassOf obo:VO_0016956 .

obo:VO_0015999 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0015660 , obo:VO_0015785 .

obo:VO_0016183 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Mevita" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0019497 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injection [Hiberix]" ;
  rdfs:subClassOf obo:VO_0010715 , obo:VO_0015016 .

obo:VO_0002174 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1791.15)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0020967 a rdfs:Class ;
  rdfs:label "Influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.009 MG/ML" ;
  rdfs:subClassOf obo:VO_0003521 .

obo:VO_0001472 a rdfs:Class ;
  rdfs:label "horse vaccine" ;
  rdfs:comment "Vaccine that used for immunizing horse." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001218 .

obo:VO_0020428 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0020469 .

obo:VO_0000882 a rdfs:Class ;
  rdfs:label "single-dose Vaxigrip vaccine" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0000868 .

obo:VO_0016995 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:VO_0002095 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Measles-Parainfluenza Modified Live Virus Vaccine (USDA: 1341.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002406 , obo:VO_0007748 .

obo:VO_0016681 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0012161 a rdfs:Class ;
  rdfs:label "bovine leukemia virus vaccine" ;
  rdfs:comment "A vaccine that protects against Bovine Leukemia virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:PR_000050567 a rdfs:Class ;
  rdfs:label "obsolete protein-containing material entity" ;
  rdfs:comment "OBSOLETE. A material entity that minimally consists of a protein." .

obo:VO_0010028 a rdfs:Class ;
  rdfs:label "Leishmania  major PEPCK" ;
  rdfs:comment "A PEPCK protein that is part of Leishmania  major" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0007166 a rdfs:Class ;
  rdfs:label "rF-PSA/PSMA/TRICOM Vaccine" ;
  rdfs:comment "A synthetic fowlpox viral vaccine containing the tumor-associated antigens prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; TRICOM). Vaccination with this viral vaccine may enhance antigen presentation and activate cytotoxic T-cells against PSA- or PSMA-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:OBI_0000450 a rdfs:Class ;
  rdfs:label "regulatory agency"@en ;
  rdfs:comment "A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:VO_0004041 a rdfs:Class ;
  rdfs:label "Pseudorabies Subunit gB protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000750 .

obo:VO_0004847 a rdfs:Class ;
  rdfs:label "Trumenba Injectable Product" ;
  rdfs:subClassOf obo:VO_0003081 .

obo:VO_0020208 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (BA.4/BA.5) 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0020497 .

obo:NCBITaxon_422676 a rdfs:Class ;
  rdfs:label "Aconoidasida" ;
  rdfs:subClassOf obo:NCBITaxon_5794 .

obo:VO_0018208 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 TCID / Mumps virus 12500 TCID / Rubella virus 1000 TCID Injection [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0018206 , obo:VO_0018207 .

obo:VO_0003063 a rdfs:Class ;
  rdfs:label "obsolete RB51 induced protection against B.abortus" .

obo:VO_0020631 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0020615 , obo:VO_0021038 .

obo:VO_0015196 a rdfs:Class ;
  rdfs:label "obsolete 1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe" .

obo:VO_0010242 a rdfs:Class ;
  rdfs:label "assay sample endpoint variable" ;
  rdfs:comment "A variable representing the timepoint a biological sample was taken after vaccination" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:PR_000011271 a rdfs:Class ;
  rdfs:label "NACHT, LRR and PYD domains-containing protein 3" ;
  rdfs:comment "A protein that is a translation product of the human NLRP3 gene or a 1:1 ortholog thereof." ;
  rdfs:subClassOf obo:PR_000000001 .

obo:VO_0003524 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0003523 , obo:VO_0004914 .

obo:VO_0017523 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] Box of 10" ;
  rdfs:subClassOf obo:VO_0017522 , obo:VO_0017526 .

obo:VO_0004053 a rdfs:Class ;
  rdfs:label "Streptococcus pyogenes Emm1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0002852 .

obo:VO_0000955 a rdfs:Class ;
  rdfs:label "host survival to pathogen challenge after vaccination" ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0002662 a rdfs:Class ;
  rdfs:label "tolA from Salmonella Typhimurium" ;
  rdfs:comment "A tolA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0002693 a rdfs:Class ;
  rdfs:label "pcm from Yersinia pestis" ;
  rdfs:comment "A pcm mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001426 .

obo:OPL_0000050 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum microgametocyte" ;
  rdfs:comment "A Plasmodium falciparum gametocyte that is a male gametocyte and found in either bloodstream of a human host or midgut of a mosquito vector. The microgametocyte is a precursor cell of the microgamete." ;
  rdfs:subClassOf obo:OPL_0000249 , obo:OPL_0000269 .

obo:VO_0020327 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2022-2023 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003067 , obo:VO_0010428 .

obo:VO_0015189 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0015179 , obo:VO_0015273 .

obo:VO_0007328 a rdfs:Class ;
  rdfs:label "Bcl-Xs adenovirus vaccine" ;
  rdfs:comment "A vaccine consisting of replication-defective recombinant adenovirus that encodes for Bcl-Xs with potential antineoplastic activity. Vaccination with Bcl-Xs adenovirus vaccine induces apoptosis in Bcl-2 and Bcl-XL positive cancer cells, resulting in decreased tumor growth while leaving normal cells unaffected. Bcl-Xs block the function of the protooncogenes Bcl-2 and Bcl-XL which are overexpressed in a variety of solid tumors and promote cancer cell survival by inhibiting apoptosis. (NCI04)A vaccine consisting of replication-defective recombinant adenovirus that encodes for Bcl-Xs with potential antineoplastic activity. Vaccination with Bcl-Xs adenovirus vaccine induces apoptosis in Bcl-2 and Bcl-XL positive cancer cells, resulting in decreased tumor growth while leaving normal cells unaffected. Bcl-Xs block the function of the protooncogenes Bcl-2 and Bcl-XL which are overexpressed in a variety of solid tumors and promote cancer cell survival by inhibiting apoptosis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0003288 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003342 .

obo:VO_0007039 a rdfs:Class ;
  rdfs:label "recombinant Vaccinia-CEA(6D)-TRICOM vaccine" ;
  rdfs:comment "A vaccine consisting of recombinant vaccinia virus encoding the tumor-associated antigen carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-CEA(6D)-TRICOM vaccine stimulates the host immune system to mount a T-cell response against tumor cells expressing the CEA antigen. The use of TRICOM in the vaccine may elicit a greater antitumor cytotoxic T lymphocyte (CTL) immune response compared to the use of vaccinia-CEA alone." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0010707 a rdfs:Class ;
  rdfs:label "Avaxim - Pediatric vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010438 .

obo:VO_0000900 a rdfs:Class ;
  rdfs:label "challenge dose" ;
  rdfs:comment "A dose of a virulent pathogen used for a vaccine challenge process." ;
  rdfs:subClassOf obo:OBI_0000984 .

obo:VO_0016855 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Revaxis] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016803 .

obo:VO_0002647 a rdfs:Class ;
  rdfs:label "obsolete lppB from Salmonella spp." ;
  rdfs:comment "An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" .

obo:VO_0000612 a rdfs:Class ;
  rdfs:label "vaccine organism virulent" ;
  rdfs:comment "a virulence of vaccine that shows a virulent pheontype of the organism as the major component of a vaccine. The virulent phenotype means that an vaccine organism is virulent and is able to cause a pathogenic phenotype in a host organism." ;
  rdfs:subClassOf obo:PATO_0002146 .

obo:VO_0017198 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0017188 , obo:VO_0017637 .

obo:VO_0004132 a rdfs:Class ;
  rdfs:label "Chloroform-methanol residue (CMR) vaccine" ;
  rdfs:subClassOf obo:VO_0000463 .

obo:VO_0004160 a rdfs:Class ;
  rdfs:label "Rotavirus VP2/VP 6 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000658 .

obo:VO_0002050 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Variant Strain, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C2.52)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0018415 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 7F vaccine 0.001 MG" ;
  rdfs:subClassOf obo:VO_0003253 .

obo:OPL_0000265 a rdfs:Class ;
  rdfs:label "Plasmodium macrogamete" ;
  rdfs:comment "A Plasmodium gamete that is in a matured form of the macrogametocyte and found in the midgut of a mosquito vector. The macrogamete is fertilized by the microgamete, forming the zygote." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000264 .

obo:VO_0011397 a rdfs:Class ;
  rdfs:label "Human papillomavirus L2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000667 .

obo:VO_0020708 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0020702 .

obo:VO_0018271 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003862 .

obo:VO_0001770 a rdfs:Class ;
  rdfs:label "equine influenza killed virus vaccine (USDA: 1505.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0001176 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0007711 a rdfs:Class ;
  rdfs:label "neoantigen-loaded autologous dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous DCs loaded with immunogenic peptides derived from autologous cancer cells, with potential immunomodulating and antineoplastic activities. Vaccination with the neoantigen-loaded autologous DC vaccine stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the neoantigens, which results in tumor cell lysis. Neoantigens arising from the mutations of the tumor genome expressed specifically on the tumor cell instead of normal cells, suggesting that vaccines targeting neoantigens should generate a highly tumor-specific response with minimal off-target effects. Neoantigens are identified from tumor tissues from a gastric cancer, hepatocellular carcinoma, lung cancer or colorectal cancer patient. Dendritic cells are then primed with synthesized peptides. The vaccine can be combined with microwave ablation ti treat patients with Hepatocellular Carcinoma (HCC). It can also be combined with Anti-PD1 (Nivolumab) as for patients with resected Hepatocellular Carcinoma (HCC) and Liver Metastases From Colorectal Cancer (CRLM). " ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0016125 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 25 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015879 .

obo:PATO_0000918 a rdfs:Class ;
  rdfs:label "volume" ;
  rdfs:comment "A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:VO_0003023 a rdfs:Class ;
  rdfs:label "vaccine reconstitution" ;
  rdfs:comment "A vaccine prepration process that mixes vaccine lyophilized powder and diluent liquid. The process forms a vaccine that can be used for administration. This term can also be considered as a child term of OBI term 'material combination'. " ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0002308 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus Modified Live Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 49C1.21)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000619 , obo:VO_0001220 , obo:VO_0002471 , obo:VO_0007748 .

obo:VO_0010394 a rdfs:Class ;
  rdfs:label "vaccine multivalent role" ;
  rdfs:comment "A vaccine that is designed to immunize against multiple antigen or multiple strain of a pathogen." ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0015551 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine Prefilled Syringe [Heptavax]" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:OPMI_0000445 a rdfs:Class ;
  rdfs:label "biomarker"@en ;
  rdfs:comment "Material entity that has a measurable quality, or that participates in a measurement process profile, which can be used as an indicator of an underlying biological state or identity." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCBITaxon_33317 a rdfs:Class ;
  rdfs:label "Protostomia" ;
  rdfs:subClassOf obo:NCBITaxon_33213 .

obo:NCBITaxon_10255 a rdfs:Class ;
  rdfs:label "Variola virus" ;
  rdfs:subClassOf obo:NCBITaxon_10242 .

obo:VO_0002530 a rdfs:Class ;
  rdfs:label "drrC from Mycobacterium tuberculosis" ;
  rdfs:comment "A drrC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0019664 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0020273 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 5 LFU Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020272 .

obo:VO_0017599 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017597 , obo:VO_0017604 .

obo:VO_0021025 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 PFU/ML [Zostavax]" ;
  rdfs:subClassOf obo:VO_0000124 , obo:VO_0021024 .

obo:VO_0002887 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP mutant vaccine" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" .

obo:VO_0017563 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax]" ;
  rdfs:subClassOf obo:VO_0017551 , obo:VO_0017555 .

obo:VO_0007334 a rdfs:Class ;
  rdfs:label "Canarypox-hIL-12 melanoma vaccine" ;
  rdfs:comment "A vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) that encodes the gene for human interleukin-12 (hIL-12). Produced mainly by B-cells, IL-12 is an endogenous cytokine that activates natural killer (NK) cells, promotes cytotoxic T lymphocyte (CTL) responses, induces the release of interferon-gamma (IFN-gamma), and may exhibit antitumor and anti-angiogenic effects. Vaccination with canarypox-hIL-12 melanoma vaccine may stimulate the host immune system to mount an immune response against tumor cells, thereby inhibiting tumor growth and/or metastasis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0004517 a rdfs:Class ;
  rdfs:label "PsaA DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000675 .

obo:VO_0015528 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015520 , obo:VO_0015555 .

obo:VO_0001129 a rdfs:Class ;
  rdfs:label "non-replicating adenovirus accine vector" ;
  rdfs:comment "an adenovirus vaccine vector that is not able to replicate." ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0021093 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0019939 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003611 .

obo:VO_0017934 a rdfs:Class ;
  rdfs:label "Haemophilus B Conjugate Vaccine / meningococcal group C polysaccharide Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017814 .

obo:VO_0017848 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine Injectable Suspension [Menjugate]" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0010726 , obo:VO_0017899 .

obo:VO_0016670 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0003429 .

obo:OGG_3000888225 a rdfs:Class ;
  rdfs:label "leuD" ;
  rdfs:comment "Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI)" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0004454 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine pVR1020-GRA1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:VO_0016749 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Pur] Box of 10" ;
  rdfs:subClassOf obo:VO_0016713 , obo:VO_0016768 .

obo:VO_0019425 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus capsular oligosaccharide Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0010445 , obo:VO_0020836 .

obo:VO_0002600 a rdfs:Class ;
  rdfs:label "purF from Francisella tularensis" ;
  rdfs:comment "Mice, which had been immunized with at least 6.95 x 103 cfu of F. tularensis U112 purF::Cm, were protected against the subsequent F. tularensis subspecies novicida challenge." ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0004820 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G4 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010449 .

obo:VO_0018254 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 20000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0000173 a rdfs:Class ;
  rdfs:label "vaccine organism live attenuated" ;
  rdfs:comment "a virulence of vaccine organism that shows an attenuated pheontype of the organism as the major component of a vaccine." ;
  rdfs:subClassOf obo:PATO_0002146 .

obo:VO_0002945 a rdfs:Class ;
  rdfs:label "obsolete Yersinia pestis smpB/ssrA mutant vaccine" ;
  rdfs:comment "An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis" .

obo:VO_0003529 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0003526 .

obo:VO_0010457 a rdfs:Class ;
  rdfs:label "seasonal licensed human influenza virus vaccine" ;
  rdfs:subClassOf obo:VO_0010415 .

obo:VO_0000794 a rdfs:Class ;
  rdfs:label "wboA from B. abortus strain 2308" ;
  rdfs:comment "A Brucella abortus gene that has the name wboA and comes from strain 2308. " ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000793 .

obo:VO_0019701 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [FluLaval Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003763 , obo:VO_0010427 .

obo:VO_0000354 a rdfs:Class ;
  rdfs:label "obsolete B. ovis microparticle subunit vaccine" .

obo:VO_0015493 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003416 .

obo:VO_0001535 a rdfs:Class ;
  rdfs:label "Fox Encephalitis Killed Virus Vaccine (USDA: 1635.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001464 , obo:VO_0001489 , obo:VO_0007748 .

obo:VO_0007550 a rdfs:Class ;
  rdfs:label "HLA-A*2404-Restricted RNF43-TOMM34-VEGFR1-VEGFR2 multipeptide vaccine" ;
  rdfs:comment "A cancer vaccine containing four HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this vaccine are derived from ring finger protein 43 (RNF43); translocase of outer mitochondrial membrane 34 (TOMM34); and vascular endothelial growth factor receptors (VEGFR) 1 and 2. Upon administration, HLA-A*2404-restricted RNF43-TOMM34-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing RNF43, TOMM34, and VEGFR 1 and 2 peptides, resulting in tumor cell lysis and decreased tumor growth. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenic peptide immunogenicity" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0007260 a rdfs:Class ;
  rdfs:label "anti-CTLA4 MoAb RNA/GITRL RNA-transfected autologous dendritic cell vaccine" ;
  rdfs:comment "An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. Anti-CTLA4 MoAb RNA/GITRL RNA-transfected DC vaccine is prepared by transfecting DCs with RNAs encoding humanized heavy and light chains of the anti-CTLA4 (cytotoxic T-Lymphocyte-Associated Antigen 4) monoclonal antibody and tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18 or GlTRL); expression of anti-CTLA4 blocks the inhibitory effect of CTLA4 on the activation of T-lymphocytes, while expression of GlTRL modulates T lymphocyte survival in peripheral tissues. Co-vaccination of this vaccine with melanoma antigen specific vaccine may eliminate the adverse effects associated with systemic administration of immune modulators, while also enhancing vaccine-induced immune responses." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0001060 a rdfs:Class ;
  rdfs:label "Newcastle disease virus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a NewCastle virus strain" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0003456 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 50 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0016454 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0007703 a rdfs:Class ;
  rdfs:label "multiple signals loaded dendritic cells vaccine" ;
  rdfs:comment "A cancer vaccine that can efficiently present T cells with antigens of HCC sensitize their antitumor properties meanwhile low dose cyclophosphamide (CY) can effectively improve the microenvironment of immunity. Multiple signals loaded dendritic cells vaccine combined low dose of cyclophosphamide combining with radical surgery or TACE or targeted agents for patients with hepatocellular carcinoma coul prolong their survival time." ;
  rdfs:subClassOf obo:VO_0005499 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0001875 a rdfs:Class ;
  rdfs:label "Bovine Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1161.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002330 .

obo:VO_0012401 a rdfs:Class ;
  rdfs:label "Tp92" ;
  rdfs:comment "Immunization with recombinant Tp92 partially protected rabbits from subsequent T. pallidum challenge [PubMed: 10762571]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012358 .

obo:DOID_5409 a rdfs:Class ;
  rdfs:label "lung small cell carcinoma"@en ;
  rdfs:comment "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung."@en ;
  rdfs:subClassOf obo:DOID_3905 .

obo:VO_0015001 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Twinrix]" ;
  rdfs:subClassOf obo:VO_0003451 .

obo:VO_0017408 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017327 .

obo:VO_0010229 a rdfs:Class ;
  rdfs:label "reserved cvx code for not using" ;
  rdfs:comment "An information content entity that specifies the CVX code that will not be used to avoid confusion with code 999." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0011176 a rdfs:Class ;
  rdfs:label "Mpt63" ;
  rdfs:comment "MPT63 (Rv1926c), a major secreted protein of Mycobacterium tuberculosis, is immunoreactive in antibody assays in humans and animals and provides protection as a combined DNA vaccine in mice [PubMed: 19281533]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0017952 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injection [Meningitec] Box of 10" ;
  rdfs:subClassOf obo:VO_0017906 .

obo:OPL_0000150 a rdfs:Class ;
  rdfs:label "gametocyte stage" ;
  rdfs:comment "A life cycle stage where a cell differentiates into male or female sexual forms." ;
  rdfs:subClassOf obo:UBERON_0000105 .

obo:VO_0010308 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/9/2014 antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003519 , obo:VO_0010301 .

obo:VO_0017119 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017118 .

obo:VO_0015748 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015813 .

obo:VO_0018175 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018173 , obo:VO_0018179 .

obo:VO_0003760 a rdfs:Class ;
  rdfs:label "FluLaval Quadrivalent 2016-2017 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003758 .

obo:VO_0020926 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0003502 , obo:VO_0004914 .

obo:VO_0020513 a rdfs:Class ;
  rdfs:label "Vibrio cholerae as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0019277 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Washington/19/2020 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020334 .

obo:VO_0020292 a rdfs:Class ;
  rdfs:label "Vibrio cholerae CVD 103-HGR strain live antigen Oral Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0006004 , obo:VO_0010312 .

obo:VO_0020660 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] Box of 5" ;
  rdfs:subClassOf obo:VO_0020657 , obo:VO_0020705 .

obo:VO_0007234 a rdfs:Class ;
  rdfs:label "Allogenic Glioma Cancer Vaccine" ;
  rdfs:comment "A vaccine composed of killed glioma cancer cells from another patient for use in immunotherapy" ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0000574 a rdfs:Class ;
  rdfs:label "route of administration" ;
  rdfs:comment "A path that is located in gross anatomical part of an organism (e.g., human) and is used for administering a vaccine, a drug, fluid, poison, or other substance into the body. " ;
  rdfs:seeAlso <http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38114> , <http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C66729> ;
  rdfs:subClassOf obo:BFO_0000029 .

obo:VO_0021092 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0020929 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0020215 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0020498 .

obo:VO_0017678 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0016660 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Tisida" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0001639 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.0A)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0002163 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1771.17)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0002348 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000768 , obo:VO_0002347 .

obo:VO_0010036 a rdfs:Class ;
  rdfs:label "Neospora caninum PDI" ;
  rdfs:comment "A PDI protein that is part of Neospora caninum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0004438 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine hugp100 encoding gp100" ;
  rdfs:comment "Gene name: gp100" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0010923 a rdfs:Class ;
  rdfs:label "AMA1 from P. falciparum 3D7" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0001404 a rdfs:Class ;
  rdfs:label "Mycobacterium avium gene" ;
  rdfs:comment "A bacterial gene that is from Mycobacterium avium." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0019396 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.08 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 12 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017799 , obo:VO_0018770 .

obo:NCBITaxon_5658 a rdfs:Class ;
  rdfs:label "Leishmania <genus>" ;
  rdfs:subClassOf obo:NCBITaxon_5654 .

obo:VO_0010804 a rdfs:Class ;
  rdfs:label "Marek's disease virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0010456 a rdfs:Class ;
  rdfs:label "licensed human yellow fever virus vaccine" ;
  rdfs:comment "yellow fever virus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000123 , obo:VO_0000635 .

obo:NCBITaxon_1437010 a rdfs:Class ;
  rdfs:label "Boreoeutheria" ;
  rdfs:subClassOf obo:NCBITaxon_40674 .

obo:VO_0001800 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome Reproductive & Respiratory Form, Modified Live Virus Vaccine (USDA: 19T1.21)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001511 , obo:VO_0007748 .

obo:VO_0018331 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0018318 .

obo:DOID_1909 a rdfs:Class ;
  rdfs:label "melanoma"@en ;
  rdfs:comment "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye."@en ;
  rdfs:subClassOf obo:DOID_0050687 .

obo:VO_0010372 a rdfs:Class ;
  rdfs:label "Pentacel - (inactivated poliovirus component grown in Vero cells) vaccine" ;
  rdfs:subClassOf obo:VO_0000084 .

obo:VO_0019777 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2021 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020492 .

obo:OBI_0003610 a rdfs:Class ;
  rdfs:label "reactant role"@en ;
  rdfs:comment "A role borne by a biological or chemical entity that participates or has molecular components that participate in a chemical reaction."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0003471 a rdfs:Class ;
  rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010303 , obo:VO_0010415 .

obo:VO_0015316 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injectable Suspension [Hav Sorbat Ssw]" ;
  rdfs:subClassOf obo:VO_0015315 .

obo:VO_0005399 a rdfs:Class ;
  rdfs:label "Osvid-19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Osve Pharmaceutical Company." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005201 .

obo:VO_0002098 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine (USDA: 13A1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002394 , obo:VO_0007748 .

obo:VO_0016497 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015979 .

obo:VO_0016006 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 50" ;
  rdfs:subClassOf obo:VO_0003424 .

obo:VO_0016818 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0016733 , obo:VO_0016767 .

obo:VO_0002540 a rdfs:Class ;
  rdfs:label "phoP from Mycobacterium tuberculosis" ;
  rdfs:comment "Study evaluated immunogenicity and protection against Mycobacterium tuberculosis in rhesus monkeys with an attenuated M. tuberculosis with a disrupted phoP gene (SO2) as a single-dose vaccine. SO2 treatment showed reduced average lung bacterial counts (1.0 and 1.2 log respectively, compared with 0.4 log for BCG) and significant protective effect by reduction in C-reactive protein levels, body weight loss, and decrease of erythrocyte-associated hematologic parameters (MCV, MCH, Hb, Ht) as markers of inflammatory infection, all relative to non-vaccinated controls" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0010416 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2013-2014" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0015813 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015496 .

obo:VO_0016381 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 25 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015944 .

obo:IAO_8000007 a rdfs:Class ;
  rdfs:label "curation subset ontology module"@en ;
  rdfs:comment "A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:VO_0016534 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0003457 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 25 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0011331 a rdfs:Class ;
  rdfs:label "URE" ;
  rdfs:comment "Recombinant urease (rURE) of C. immitis was expressed in Escherichia coli and tested asa vaccine candidate in BALB/c mice. BALB/c mice immunized subcutaneously with rURE and subsequently challenged by the intraperitoneal (i.p.) route with a lethal inoculum of C. immitis arthroconidia demonstrated a significant reduction in the level of C. immitis infection compared to control animals [PubMed: 11292702]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010853 .

obo:UBERON_0018707 a rdfs:Class ;
  rdfs:label "bladder organ" ;
  rdfs:comment "A membranous sac in animals that serves as the receptacle of a liquid or contains gas." ;
  rdfs:subClassOf obo:UBERON_0000062 .

obo:VO_0001592 a rdfs:Class ;
  rdfs:label "avian influenza H4N6 Subtype, Killed Virus Vaccine (USDA: 1057.H4)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0001202 a rdfs:Class ;
  rdfs:label "challenge dose (unit: CFU)" ;
  rdfs:comment "A challenge dose that is represented with the unit of colony forming units (CFU)." ;
  rdfs:subClassOf obo:VO_0000900 .

obo:VO_0015055 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0015054 .

obo:VO_0004203 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni PorA protein vaccine" ;
  rdfs:subClassOf obo:VO_0012182 .

obo:VO_0007700 a rdfs:Class ;
  rdfs:label "multi-epitope melanoma peptide vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a combination of peptides derived form several melanoma epitopes. Vaccination with multi-epitope melanoma peptide vaccine stimulates the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the corresponding antigens, resulting in tumor cell lysis. This vaccine may stimulate a broader CTL response compared to single-antigen vaccines. Vaccines made from melanoma peptides or antigens may help the body build an effective immune response to kill tumor cells in patients with stage IIC-IV melanoma. This vaccine is a tyrosinase/gp100/MAGE-3 class I peptide vaccine combined with Montanide ISA 51 or ISA 51 VG with CpG adjuvant 7909 in human leukocyte antigen (HLA) class I A1, A3 or A11 and B44 matched patients with surgically resected stages IIC, III and IV melanoma." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0017239 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Hepatitis B Surface Antigen Vaccine / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000743 , obo:VO_0017808 .

obo:VO_0020830 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0020827 .

obo:BFO_0000011 a rdfs:Class ;
  rdfs:label "spatiotemporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:VO_0011140 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1))" ;
  rdfs:comment "Immunization with DNA/rAd5 vaccines encoding HA derived from Influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1)) conferred protection in ferrets against a stringent virus challenge [PubMed: 20352112]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0010733 a rdfs:Class ;
  rdfs:label "obsolete Prevnar (Canada)" ;
  rdfs:comment "Trade Name: Prevnar" .

obo:VO_0020422 a rdfs:Class ;
  rdfs:label "obsolete Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10" .

obo:VO_0003784 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003070 , obo:VO_0010432 .

obo:VO_0016738 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0016707 , obo:VO_0016771 .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity"@en ;
  rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:VO_0003271 a rdfs:Class ;
  rdfs:label "Infanrix Penta vaccine" ;
  rdfs:comment "A combination vaccine against diphtheria, tetanus, pertussis, hepatitis B, and poliovirus." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000743 .

obo:VO_0017282 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Tripacel]" ;
  rdfs:subClassOf obo:VO_0010742 , obo:VO_0018776 .

obo:DOID_345 a rdfs:Class ;
  rdfs:label "uterine disease"@en ;
  rdfs:comment "A female reproductive system disease that is located_in the uterus."@en ;
  rdfs:subClassOf obo:DOID_229 .

obo:VO_0019639 a rdfs:Class ;
  rdfs:label "influenza A virus (H3N2) antigen 0.03 MG/ML / influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML [Fluzone Quadrivalent 2020 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020490 .

obo:VO_0003795 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2017-2018 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003792 .

obo:VO_0021041 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution [Varilrix]" ;
  rdfs:subClassOf obo:VO_0010746 , obo:VO_0021040 .

obo:VO_0020112 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine Injectable Suspension [Cervarix]" ;
  rdfs:subClassOf obo:VO_0018652 , obo:VO_0020111 .

obo:VO_0004846 a rdfs:Class ;
  rdfs:label "MENVEO vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0004844 .

obo:VO_0005030 a rdfs:Class ;
  rdfs:label "pUMVC3 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pUMVC3.  This plasmid is 4030 base pairs in length and contains a CMV promoter and kanamycin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0017627 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 2" ;
  rdfs:subClassOf obo:VO_0017610 .

obo:VO_0001850 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live & Killed Virus, Modified Live Chlamydia Vaccine (USDA: 1559.2B)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0002434 , obo:VO_0007748 .

obo:VO_0010015 a rdfs:Class ;
  rdfs:label "Leishmania  donovani FML" ;
  rdfs:comment "A FML protein that is part of Leishmania  donovani" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0000359 a rdfs:Class ;
  rdfs:label "lentivirus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a lentivirus as the vector." ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0011545 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni DNA vaccine pcDNA3.1(+)-cadF" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012182 .

obo:VO_0016706 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0005418 a rdfs:Class ;
  rdfs:label "authorized COVID-19 virus-like particle vaccine" ;
  rdfs:subClassOf obo:VO_0005205 , obo:VO_0005264 .

obo:VO_0002563 a rdfs:Class ;
  rdfs:label "manA from B. melitensis" ;
  rdfs:comment "Unmarked rough B. abortus and B. melitensis deletion mutants of manBA (including manA and manB) were attenuated. These mutants provided protection against virulent Brucella challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001400 .

obo:VO_0017103 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 10" ;
  rdfs:subClassOf obo:VO_0017102 , obo:VO_0017114 , obo:VO_0017571 .

obo:VO_0003378 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injection [Stamaril]" ;
  rdfs:subClassOf obo:VO_0003377 .

obo:VO_0021172 a rdfs:Class ;
  rdfs:label "0.3 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (XBB.1.5) 0.1 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0021170 .

obo:VO_0018062 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 40" ;
  rdfs:subClassOf obo:VO_0018053 , obo:VO_0018079 , obo:VO_0018149 .

obo:VO_0003738 a rdfs:Class ;
  rdfs:label "Afluria 2018-2019 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003737 .

obo:VO_0017632 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017592 , obo:VO_0017631 .

obo:VO_0003594 a rdfs:Class ;
  rdfs:label "Fluzone 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 , obo:VO_0010431 .

obo:VO_0002282 a rdfs:Class ;
  rdfs:label "Newcastle Disease-Bronchitis Mass & Ark Types, Killed Virus Vaccine-Salmonella Enteritidis Bacterin (USDA: 48D7.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002453 , obo:VO_0007748 .

obo:VO_0001263 a rdfs:Class ;
  rdfs:label "QuilA vaccine adjuvant" ;
  rdfs:comment "A tenosactive compound vaccine adjuvant that contains purified extract from the bark of the South American tree Quillaja saponaria Molina." ;
  rdfs:subClassOf obo:VO_0001358 .

obo:VO_0011505 a rdfs:Class ;
  rdfs:label "WEEV DNA vaccine encoding 6K-E1 protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012188 .

obo:VO_0018465 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 20" ;
  rdfs:subClassOf obo:VO_0018435 , obo:VO_0018449 .

obo:VO_0021108 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020346 .

obo:VO_0016190 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:VO_0020824 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.02 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0017566 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] Box of 5" ;
  rdfs:subClassOf obo:VO_0017563 , obo:VO_0017580 .

obo:VO_0016077 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015868 .

obo:OPL_0000048 a rdfs:Class ;
  rdfs:label "Trypanosoma brucei lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Trypanosoma brucei." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0003665 a rdfs:Class ;
  rdfs:label "YF-Vax Injectable Product" ;
  rdfs:subClassOf obo:VO_0000121 .

obo:VO_0003754 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2018-2019 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003752 .

obo:VO_0017923 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injection [Nimenrix]" ;
  rdfs:subClassOf obo:VO_0003080 , obo:VO_0017820 .

obo:VO_0021112 a rdfs:Class ;
  rdfs:label "influenza A virus A/Delaware/39/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Nebraska/14/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020333 .

obo:VO_0000014 a rdfs:Class ;
  rdfs:label "Biothrax vaccine" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010291 , obo:VO_0010434 .

obo:VO_0016086 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 20 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015870 .

obo:VO_0011117 a rdfs:Class ;
  rdfs:label "HA from Influenza B virus (Strain B/England/222/82)" ;
  rdfs:comment "Immunization and challenge experiments in mice indicated that even though vaccination with the recombinant HA vaccinia viruses derived from Influenza B virus (Strain B/England/222/82) induced different levels of cross-reactive neutralizing antibodies, mice vaccinated with either recombinant vaccinia virus were protected from infection with either subpopulation of influenza virus [PubMed: 3318092]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0016829 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0016735 , obo:VO_0016778 .

obo:VO_0017908 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine Injectable Suspension [Menjugate]" ;
  rdfs:subClassOf obo:VO_0017848 , obo:VO_0017933 .

obo:VO_0019712 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0003792 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003791 .

obo:VO_0015294 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe [Epaxal] Box of 1" ;
  rdfs:subClassOf obo:VO_0015293 , obo:VO_0015296 .

obo:VO_0012365 a rdfs:Class ;
  rdfs:label "znuA" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0016804 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Revaxis] Box of 20" ;
  rdfs:subClassOf obo:VO_0016726 , obo:VO_0016746 , obo:VO_0016821 .

obo:VO_0020788 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 500000000 CFU" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0019465 .

obo:VO_0011422 a rdfs:Class ;
  rdfs:label "Measles Virus vaccine VEE/SIN-H+F" ;
  rdfs:subClassOf obo:VO_0000654 .

obo:VO_0017770 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003196 , obo:VO_0017799 .

obo:VO_0007687 a rdfs:Class ;
  rdfs:label "MAGE-A1, Her-2/neu, FBP peptides ovarian cancer vaccine" ;
  rdfs:comment "A cancer vaccine comprised of multiple peptides derived from MAGE-1A, Her-2/neu, and folate binding protein (FBP), with potential immunostimulating and antineoplastic properties. The MAGE-A1, Her-2/neu, FBP peptides cancer vaccine includes the peptides MAGE-A1:161-169, FBP:191-199, Her-2/neu:369-377, MAGE-A1:96-104, and Her-2/neu:754-762. Vaccination with this cancer vaccine may activate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing the corresponding antigens, resulting in tumor cell lysis. The vaccine compromises synthetic ovarian cancer-associated peptides administered with a synthetic tetanus toxoid helper peptide emulsified in Montanide ISA-51 before or after paclitaxel and carboplatin in patients with stage III-IV ovarian epithelial, primary peritoneal cavity, or fallopian tube cancer undergoing optimal cytoreductive surgery. Vaccines made from peptides may help the body build an effective immune response to kill tumor cells. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving vaccine therapy and chemotherapy after surgery may kill any tumor cells that remain after surgery." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0010995 a rdfs:Class ;
  rdfs:label "IpaC" ;
  rdfs:comment "The invasiveness and virulence of Shigella spp. are largely due to the expression of plasmid-encoded virulence factors, among which are the invasion plasmid antigens (IpaB, IpaC, and IpaD). Recent observations have indicated that the Ipa proteins (IpaB, IpaC, and possibly IpaD) form a multiprotein complex capable of inducing the phagocytic event which internalizes the bacterium.  Researchers isolated a complex of invasins and LPS from water-extractable antigens of virulent shigellae.  Western blot analysis of the complex indicates that all of the major virulence antigens of Shigella, including IpaB, IpaC, and IpaD, and LPS are components of this macromolecular complex.  Guinea pigs (keratoconjunctivitis model) or mice (lethal lung model) immunized intranasally with purivied invasin complex (invaplex) on days 0, 14, and 28 and challenged 3 weeks later with virulent shigellae were protected from disease (P<0.01 for both animal models) [PubMed: 11083774]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010777 .

obo:VO_0001524 a rdfs:Class ;
  rdfs:label "porcine circovirus 2 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Porcine circovirus 2 infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 , obo:VO_0001474 .

obo:VO_0004156 a rdfs:Class ;
  rdfs:label "Pseudorabies recombinant vector vaccine encoding gp50 and gII protein" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000750 , obo:VO_0001474 .

obo:VO_0019761 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0016017 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 25" ;
  rdfs:subClassOf obo:VO_0003425 .

obo:VO_0002682 a rdfs:Class ;
  rdfs:label "virG from Shigella" ;
  rdfs:comment "A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000169 .

obo:VO_0017067 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017544 .

obo:VO_0017839 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Intramuscular Solution [Menactra]" ;
  rdfs:subClassOf obo:VO_0017891 .

obo:VO_0015854 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] by Merck" ;
  rdfs:subClassOf obo:VO_0015648 .

obo:VO_0004016 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding HA from influenza A virus (A/environment/Hong Kong/156/1997(H5N1))" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0016113 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015872 .

obo:VO_0015775 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe Box of 50" ;
  rdfs:subClassOf obo:VO_0015489 .

obo:VO_0015305 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015300 .

obo:DOID_12205 a rdfs:Class ;
  rdfs:label "dengue disease"@en ;
  rdfs:comment "A viral infectious disease that results in infection, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted by Aedes mosquito bite. The infection has symptom fever, has symptom severe headache, has symptom severe pain behind the eyes, has symptom joint pain, has symptom muscle and bone pain, has symptom rash, and has symptom mild bleeding."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0000744 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine" ;
  rdfs:comment "A vaccine that protects against, Diphtheria, Tetanus, Pertussis (whooping cough), Polio, and Haemophilus influenzae type b." ;
  rdfs:subClassOf obo:VO_0000662 , obo:VO_0000742 .

obo:VO_0000666 a rdfs:Class ;
  rdfs:label "CVD 1208 vaccine" ;
  rdfs:comment "CVD 1208 is derived from wild type Shigella flexneri 2a strain 2457T and has defined deletions in four genes: (1) the guaBA chromosomal operon that encodes two enzymes (inositol 5'-monophosphate dehydrogenase and guanosine 5'synthase) essential for de novo purine biosynthesis; (2) set, a locus in a chromosomal pathogenicity island that encodes Shigella enterotoxin (ShET); (3) Pic, an autotransporter mucinase encoded on the opposite strand from set; and (4) sen, an invasiveness plasmid gene encoding ShET." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000680 , obo:VO_0001217 .

obo:VO_0003240 a rdfs:Class ;
  rdfs:label "BCG vaccine (by Organon Teknika)" ;
  rdfs:subClassOf obo:VO_0000771 .

obo:VO_0017730 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 600 UNT/ML Injectable Suspension [Acel-P] by Lederle Products" ;
  rdfs:subClassOf obo:VO_0017729 .

obo:VO_0017534 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution [Tetabulin]" ;
  rdfs:subClassOf obo:VO_0017532 , obo:VO_0017533 .

obo:VO_0001007 a rdfs:Class ;
  rdfs:label "pBC12/CMV/IL-2 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pBC12/CMV/IL-2." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0005125 a rdfs:Class ;
  rdfs:label "inactivated whole (formalin and UV radiation) SARS-CoV vaccine" ;
  rdfs:comment "A SARS inactivated vaccine made from inactivated whole virus by formalin and Ultraviolet radiation, hence Double Inactivated (DI) Vaccine" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0012183 .

obo:VO_0002805 a rdfs:Class ;
  rdfs:label "Bordetella bronchiseptica dnt mutant vaccine" ;
  rdfs:comment "A dnt mutant in Bordetella bronchiseptica was attenuated and provides protection in guinea pigs against intranasal challenge with strain L3" ;
  rdfs:subClassOf obo:VO_0000394 .

obo:VO_0001413 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda gene" ;
  rdfs:comment "A bacterial gene that is from Edwardsiella tarda." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0017946 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.03 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec]" ;
  rdfs:subClassOf obo:VO_0017907 .

obo:VO_0003475 a rdfs:Class ;
  rdfs:label "influenza A virus A/South Australia/55/2014 (H3N2) antigen" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0007486 a rdfs:Class ;
  rdfs:label "gp100-Fowlpox vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the melanoma antigen glycoprotein 100 (gp 100) with potential antineoplastic activity. The expression of gp100 may generate a cellular immune response to melanoma cells; this effect is enhanced by the co-administration of interleukin 2" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0001537 a rdfs:Class ;
  rdfs:label "Mink Distemper Modified Live Virus Vaccine (USDA: 1451.01)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0007748 , obo:VO_0010475 , obo:VO_0012178 .

obo:UBERON_0010000 a rdfs:Class ;
  rdfs:label "multicellular anatomical structure" ;
  rdfs:comment "An anatomical structure that has more than one cell as a part." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:VO_0019443 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 15 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0019948 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluvirin 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020476 .

obo:VO_0010006 a rdfs:Class ;
  rdfs:label "Eimeria acervulina 3-1E" ;
  rdfs:comment "A 3-1E protein that is part of Eimeria acervulina" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010822 .

obo:VO_0020629 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0020623 .

obo:OBI_0000070 a rdfs:Class ;
  rdfs:label "assay"@en ;
  rdfs:comment "A planned process that has the objective to produce information about a material entity (the evaluant) by examining it."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:DOID_1964 a rdfs:Class ;
  rdfs:label "fallopian tube cancer"@en ;
  rdfs:comment "A female reproductive organ cancer that is located_in fallopian tube."@en ;
  rdfs:subClassOf obo:DOID_120 .

obo:VO_0001796 a rdfs:Class ;
  rdfs:label "Lawsonia Intracellularis Avirulent Live Culture Vaccine (USDA: 10L1.01)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001105 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0016591 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Twinrix]" ;
  rdfs:subClassOf obo:VO_0000113 , obo:VO_0016594 .

obo:VO_0016771 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0016719 .

obo:VO_0001652 a rdfs:Class ;
  rdfs:label "Bursal Disease Standard & Variant, Killed Virus Vaccine (USDA: 12B5.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000960 , obo:VO_0007748 .

obo:VO_0015974 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015644 , obo:VO_0016058 .

obo:DOID_104 a rdfs:Class ;
  rdfs:label "bacterial infectious disease"@en ;
  rdfs:comment "A disease by infectious agent that results_in infection, has_material_basis_in Bacteria."@en ;
  rdfs:subClassOf obo:DOID_0050117 .

obo:OPL_0000262 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum gamete stage" ;
  rdfs:comment "A gamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000165 , obo:OPL_0000260 , obo:OPL_0000286 .

obo:VO_0020205 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.2 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020203 .

obo:VO_0019324 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.12 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.12 MG/ML Prefilled Syringe [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020478 .

obo:VO_0010293 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:NCBITaxon_11234 a rdfs:Class ;
  rdfs:label "Measles morbillivirus" ;
  rdfs:subClassOf obo:NCBITaxon_11229 .

obo:VO_0019313 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020478 .

obo:VO_0019773 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML [Fluad 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020310 .

obo:VO_0007076 a rdfs:Class ;
  rdfs:label "WT1 Peptide Vaccine OCV-501" ;
  rdfs:comment "A leukemia cancer vaccine comprised of a peptide derived from Wilms tumor gene 1 (WT1) protein, with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration, WT1 peptide vaccine OCV-501 may stimulate a CD4-positive helper T-lymphocyte-mediated immune response against WT1 expressing cells. WT1 protein, a zinc finger DNA-binding protein, is overexpressed in leukemic cells and in some solid tumors." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0010447 a rdfs:Class ;
  rdfs:label "licensed human poliovirus vaccine" ;
  rdfs:comment "Poliovirus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000664 .

obo:VO_0018621 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0018620 , obo:VO_0018638 .

obo:VO_0016839 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016760 .

obo:VO_0017260 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Covaxis]" ;
  rdfs:subClassOf obo:VO_0018771 .

obo:VO_0001729 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium Live Culture Vaccine (USDA: 19C1.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0002507 , obo:VO_0007748 .

obo:VO_0002243 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 47E5.20)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001471 , obo:VO_0002388 , obo:VO_0007748 .

obo:VO_0020226 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, vector - Ad26 100000000000 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020225 .

obo:VO_0016283 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 20 by Veron" ;
  rdfs:subClassOf obo:VO_0015925 .

obo:NCBITaxon_353210 a rdfs:Class ;
  rdfs:label "Replication competent viruses" ;
  rdfs:subClassOf obo:NCBITaxon_153135 .

obo:VO_0011064 a rdfs:Class ;
  rdfs:label "Rho" ;
  rdfs:comment "Two recombinant Mycobacterium bovis BCG (rBCG) strains carrying the Eimeria tenella rhomboid gene (Rho) delivered by extrachromosomal vector pMV261 and integrative vector pMV361 were evaluated for their ability to protect chickens against E. tenella challenge. Chickens were immunized intranasal with BCG, rBCG pMV261-Rho, or rBCG pMV361-Rho twice at a 2-week interval. All the recombinant BCG immunized chickens developed specific immune responses, and there was a significant increases of the percentages of CD4(+) and CD8(+) cells compared to the control (P<0.05). Challenge experiments demonstrated that the two rBCG strains could provide significant protection against E. tenella challenge [PubMed: 19117681]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010823 .

obo:VO_0002761 a rdfs:Class ;
  rdfs:label "UIS3 from Plasmodium yoelii" ;
  rdfs:comment "Deletion of UIS3 in Plasmodium yoelii provided attenuation and full protection in mice by Pyuis3(-) sporozoites required at least 2 immunizations against challenges with infectious sporozoites" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001452 .

obo:NCBITaxon_33554 a rdfs:Class ;
  rdfs:label "Carnivora" ;
  rdfs:subClassOf obo:NCBITaxon_314145 .

obo:VO_0016359 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:VO_0010769 a rdfs:Class ;
  rdfs:label "Marburg Virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0004490 a rdfs:Class ;
  rdfs:label "VEE virus DNA vaccine pSTU-TRDF encoding VEEV E3-E2-6K" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001499 .

obo:VO_0016549 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0015984 .

obo:VO_0000093 a rdfs:Class ;
  rdfs:label "mineral salt vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is formed as a mineral salt." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0005150 a rdfs:Class ;
  rdfs:label "rMV-S + rMV-N vaccine" ;
  rdfs:comment "A SARS DNA vaccine made up of arecombinat vector vaccine made from recombinant measles virus expressing S protein and recombinant measles virus expressing N protein." ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0000114 a rdfs:Class ;
  rdfs:label "pCAGGST7 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003218 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 12F vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0016862 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016819 .

obo:VO_0002859 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis rfaF/siaD mutant vaccine" ;
  rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0016063 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015673 , obo:VO_0015769 .

obo:NCBITaxon_2895623 a rdfs:Class ;
  rdfs:label "Metamycoplasmataceae" ;
  rdfs:subClassOf obo:NCBITaxon_2790996 .

obo:VO_0019318 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0010286 a rdfs:Class ;
  rdfs:label "pathogen gut adhesion assay" ;
  rdfs:comment "An assay that measures the gut adhesion of a pathogen within an organism." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0007628 a rdfs:Class ;
  rdfs:label "irradiated autologous cell  vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0016324 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 20 by Mtk" ;
  rdfs:subClassOf obo:VO_0015936 .

obo:VO_0018334 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabivac] Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0018320 .

obo:VO_0011345 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus DNA vaccine encoding PrM" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000665 .

obo:VO_0010801 a rdfs:Class ;
  rdfs:label "Classical swine fever virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0019733 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0020306 .

obo:VO_0007431 a rdfs:Class ;
  rdfs:label "liposomal HPV-16 E6/E7 multipeptide vaccine PDS0101" ;
  rdfs:comment "Gene name: HPV6 E6" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005488 , obo:VO_0007657 .

obo:VO_0011166 a rdfs:Class ;
  rdfs:label "H hemagglutinin protein" ;
  rdfs:comment "Chimeric Venezuelan equine encephalitis/Sindbis virus (VEE/SIN) replicon particles were used to express the hemagglutinin (H) and fusion (F) proteins of measles virus (MV).  When challenged with wild-type MV 12 to 17 months after vaccination, all vaccinated juvenile and infant monkeys vaccinated with VEE/SIN-H, VEE/SIN-H+F, and LAV were protected from rash and viremia [PubMed: 20130066]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010784 .

obo:VO_0010736 a rdfs:Class ;
  rdfs:label "Quadracel vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000714 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:NCBITaxon_5873 a rdfs:Class ;
  rdfs:label "Theileria" ;
  rdfs:subClassOf obo:NCBITaxon_5863 .

obo:VO_0003176 a rdfs:Class ;
  rdfs:label "Adenovirus Type 7 vaccine" ;
  rdfs:comment "An oral vaccine against adenovirus serotype 7." ;
  rdfs:subClassOf obo:VO_0000037 , obo:VO_0000455 , obo:VO_0000635 , obo:VO_0001220 .

obo:VO_0018918 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0020485 a rdfs:Class ;
  rdfs:label "Fluzone High-Dose 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000079 , obo:VO_0010417 .

obo:VO_0017295 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.0936 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetravac]" ;
  rdfs:subClassOf obo:VO_0017249 , obo:VO_0017294 .

obo:VO_0015263 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0001214 , obo:VO_0015231 .

obo:VO_0017385 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Boostrix]" ;
  rdfs:subClassOf obo:VO_0018788 .

obo:VO_0020782 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 ORGANISMS Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020780 , obo:VO_0020806 .

obo:VO_0019721 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003698 .

obo:VO_0020756 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain Injectable Suspension [Bcg Medac]" ;
  rdfs:subClassOf obo:VO_0020755 .

obo:VO_0002557 a rdfs:Class ;
  rdfs:label "aroA from Bordetella pertussis" ;
  rdfs:comment "An aroA mutant is highly attenuated in mice and induces significant protection from challenge with wild type B. pertussis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001409 .

obo:VO_0011194 a rdfs:Class ;
  rdfs:label "LplA" ;
  rdfs:comment "The production of a recombinant vaccine was achieved following PCR amplification of putative lipoate protein ligase (Lpl), with subsequent cloning and expression of the genes in E. coli. The putative lipoate protein ligase (Lpl) , resulted in a reduced CFU titre and a trend towards reduced mortality in an animal sepsis model [PubMed: 18034862]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0001627 a rdfs:Class ;
  rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.1F)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0015286 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015284 .

obo:VO_0000234 a rdfs:Class ;
  rdfs:label "pCR3.1 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016603 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016589 , obo:VO_0016595 .

obo:VO_0004005 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae CbpA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0019104 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017664 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Tetravac]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0015808 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 100" ;
  rdfs:subClassOf obo:VO_0015494 .

obo:VO_0001718 a rdfs:Class ;
  rdfs:label "Newcastle Disease Killed Virus Vaccine (USDA: 1705.13)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001222 , obo:VO_0007748 .

obo:VO_0016556 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0000745 , obo:VO_0001214 .

obo:VO_0003250 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 6B vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0004461 a rdfs:Class ;
  rdfs:label "Schistosoma mansoni DNA vaccine Sm23-pcDNA encoding Sm23" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003046 .

obo:VO_0004154 a rdfs:Class ;
  rdfs:label "TBEV DNA vaccine encoding E protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012190 .

obo:VO_0001837 a rdfs:Class ;
  rdfs:label "Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C Bacterin-Toxoid (USDA: 4955.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002449 , obo:VO_0007748 , obo:VO_0010475 .

obo:VO_0020976 a rdfs:Class ;
  rdfs:label "Influenza Virus Fragmented, Inactivated, Strain B / Phuket / 3073/2013 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0020973 .

obo:VO_0005479 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi vaccine" ;
  rdfs:comment "a malaria vaccine that protects against malaria caused by Plasmodium knowlesi." ;
  rdfs:subClassOf obo:VO_0000761 .

obo:VO_0020637 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe [Zostavax]" ;
  rdfs:subClassOf obo:VO_0021029 .

obo:NCBITaxon_173 a rdfs:Class ;
  rdfs:label "Leptospira interrogans" ;
  rdfs:subClassOf obo:NCBITaxon_171 .

obo:VO_0018295 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018284 .

obo:VO_0011536 a rdfs:Class ;
  rdfs:label "Measles Virus vaccine VVP" ;
  rdfs:subClassOf obo:VO_0000654 .

obo:VO_0001383 a rdfs:Class ;
  rdfs:label "unvaccinated organism" ;
  rdfs:comment "an organism that is unvaccinated with a vaccine" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:VO_0007367 a rdfs:Class ;
  rdfs:label "Cytokine-Induced Killer Cells Vaccine" ;
  rdfs:comment "A preparation of autologous lymphocytes with potential immunopotentiating and antineoplastic activities. Cytokine-induced killer (CIK) cells are CD3- and CD56-positive, non-major histocompatibility complex (MHC)-restricted, natural killer (NK)-like T lymphocytes, generated ex-vivo by incubation of peripheral blood lymphocytes (PBLs) with anti-CD3 monoclonal antibody, interleukin (IL)-2, IL-1, and interferon gamma (IFN-gamma) and then expanded. When reintroduced back to patients after autologous stem cell transplantation, CIK cells may recognize and kill tumor cells associated with minimal residual disease (MRD). CIK cells may have enhanced cytotoxic activity compared to lymphokine-activated killer (LAK) cells." ;
  rdfs:subClassOf obo:VO_0005429 , obo:VO_0007657 .

obo:VO_0000898 a rdfs:Class ;
  rdfs:label "Theileria annulata vaccine by local veterinary institutes" ;
  rdfs:subClassOf obo:VO_0000909 , obo:VO_0001466 .

obo:VO_0018046 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett)" ;
  rdfs:subClassOf obo:VO_0000664 , obo:VO_0000712 .

obo:VO_0005383 a rdfs:Class ;
  rdfs:label "BECC470s vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0000155 a rdfs:Class ;
  rdfs:label "obsolete bacterial gene" .

obo:VO_0000592 a rdfs:Class ;
  rdfs:label "Mycobacterium vaccine" ;
  rdfs:comment "Vaccine that protects against Mycobacterium bacterial infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:NCBITaxon_10090 a rdfs:Class ;
  rdfs:label "Mus musculus" ;
  rdfs:subClassOf obo:NCBITaxon_39107 .

obo:VO_0000887 a rdfs:Class ;
  rdfs:label "intradermal route" ;
  rdfs:comment "A route of administration that inject the material(such as vaccines, allergens) into the skin itself." ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0017925 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide Injectable Solution [Mengivac A + C]" ;
  rdfs:subClassOf obo:VO_0017821 .

obo:VO_0001320 a rdfs:Class ;
  rdfs:label "AS03 vaccine adjuvant" ;
  rdfs:comment "An emusion vaccine adjuvant that contains alpha-tocopherol and squalene, two biodegradable polyprenyls, in an oil-in-water emulsion." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0000068 a rdfs:Class ;
  rdfs:label "Listeria monocytogenes vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector that uses L. moncytogenes as the vector." ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0016639 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0016621 .

obo:VO_0000826 a rdfs:Class ;
  rdfs:label "Brucella abortus S19 with P39 deletion vaccine" ;
  rdfs:comment "A B. abortus vaccine that is recombinant B. abortus strain 19 vaccine with the p39 gene deletion." ;
  rdfs:subClassOf obo:VO_0001134 .

obo:NCBITaxon_50294 a rdfs:Class ;
  rdfs:label "Psittacid alphaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_180255 .

obo:VO_0021012 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML [Varilrix]" ;
  rdfs:subClassOf obo:VO_0010746 , obo:VO_0021011 .

obo:VO_0002220 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46D5.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002391 , obo:VO_0007748 .

obo:OPL_0000222 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum erythrocytic ring trophozoite" ;
  rdfs:comment "A Plasmodium falciparum erythrocytic trophozoite that is found in erythrocytes. It is a young trophozoite stage that has a typical 'ring-like' appearance. Ring-form trophozoites of Plasmodium falciparum are often thin and delicate, measuring on average 1/5 the diameter of the red blood cell." ;
  rdfs:subClassOf obo:OPL_0000244 , obo:OPL_0000283 .

obo:VO_0010237 a rdfs:Class ;
  rdfs:label "challenge-killing interval variable" ;
  rdfs:comment "A variable representing the interval between the pathogen challenge start and end" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0002157 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1762.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0016100 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015993 .

obo:VO_0000274 a rdfs:Class ;
  rdfs:label "pING DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015840 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] by MSD" ;
  rdfs:subClassOf obo:VO_0015633 .

obo:VO_0002861 a rdfs:Class ;
  rdfs:label "obsolete Neisseria meningitidis rfaF/siaD mutant vaccine" ;
  rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" .

obo:VO_0019682 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2016 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020488 .

obo:NCBITaxon_693995 a rdfs:Class ;
  rdfs:label "Coronavirinae" ;
  rdfs:subClassOf obo:NCBITaxon_11118 .

obo:VO_0016313 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015927 .

obo:VO_0016242 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix] Box of 1 by GSK" ;
  rdfs:subClassOf obo:VO_0015910 .

obo:VO_0003316 a rdfs:Class ;
  rdfs:label "Menitorix vaccine" ;
  rdfs:comment "A vaccine that can be given to children after the age of 2 months up to 2 years to prevent infectious diseases caused by Haemophilus influenzae type b (Hib) and Neisseria meningitidis group C (MenC) bacteria." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003192 , obo:VO_0010437 , obo:VO_0010444 .

obo:VO_0006092 a rdfs:Class ;
  rdfs:label "LMQ vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant that is liposome-based adjuvant of a synthetic TLR agonist and saponin induced a Th1-biased immune response." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0002770 a rdfs:Class ;
  rdfs:label "obsolete A. pleuropneumoniae HS93C-Ampr" ;
  rdfs:comment "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" .

obo:VO_0015899 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 25" ;
  rdfs:subClassOf obo:VO_0003266 .

obo:VO_0003843 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003836 .

obo:VO_0003630 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Fluzone Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003627 .

obo:VO_0018367 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003343 .

obo:VO_0017164 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017163 , obo:VO_0017183 , obo:VO_0017617 .

obo:VO_0020490 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2020 Southern Hemisphere vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010421 .

obo:VO_0001760 a rdfs:Class ;
  rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0000712 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0010729 a rdfs:Class ;
  rdfs:label "Neisvac-C vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010444 .

obo:VO_0004567 a rdfs:Class ;
  rdfs:label "Hirame rhabdovirus DNA vaccine encoding N and G" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002455 .

obo:VO_0005095 a rdfs:Class ;
  rdfs:label "Recombinant SARS-CoV-2 vaccine (Sf9 cell)" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine by West China Hospital" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 , obo:VO_0005202 .

obo:VO_0004108 a rdfs:Class ;
  rdfs:label "Mtb72f fusion protein vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:NCBITaxon_11287 a rdfs:Class ;
  rdfs:label "Viral hemorrhagic septicemia virus" ;
  rdfs:subClassOf obo:NCBITaxon_186778 .

obo:VO_0017396 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adt Booster]" ;
  rdfs:subClassOf obo:VO_0017383 , obo:VO_0017395 .

obo:VO_0016469 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0003666 a rdfs:Class ;
  rdfs:label "YF-VAX Injection" ;
  rdfs:subClassOf obo:VO_0003665 .

obo:VO_0004378 a rdfs:Class ;
  rdfs:label "Lassa fever virus recombinant vector vaccine V-LSG encoding the glycoprotein" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012177 .

obo:VO_0000195 a rdfs:Class ;
  rdfs:label "conjugate vaccine" ;
  rdfs:comment "Conjugate vaccine is vaccine that conjugates/links antigens to the molecules that form the outer coat of disease-causing bacteria to promote an immune response." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:VO_0015494 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003421 .

obo:VO_0019540 a rdfs:Class ;
  rdfs:label "human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML / human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML Prefilled Syringe [Cervarix]" ;
  rdfs:subClassOf obo:VO_0018652 , obo:VO_0019539 .

obo:VO_0010145 a rdfs:Class ;
  rdfs:label "host pathogen exposure variable" ;
  rdfs:comment "A variable representing the prior immungenic memory a host has against a specific pathogen" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0002597 a rdfs:Class ;
  rdfs:label "iglB from Francisella tularensis" ;
  rdfs:comment "Intranasal vaccination with KKF235 (F. tularensis subsp. novicida mutant (DeltaiglB) ) protected mice from subsequent homotypic challenge with U112 as well as heterotypic challenge with F. tularensis subsp. holarctica (LVS). Most significantly, oral immunization with KKF235 protected mice from a highly lethal subsp. tularensis (SCHU S4) pulmonary challenge" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0018119 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella virus vaccine Injectable Solution [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0000069 , obo:VO_0018118 .

obo:VO_0015861 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015612 , obo:VO_0015679 , obo:VO_0015989 .

obo:VO_0000065 a rdfs:Class ;
  rdfs:label "influenza virus vaccine H5N1 (Sanofi Pasteur Inc)" ;
  rdfs:comment "Product Name: Influenza Virus Vaccine, H5N1 (for National Stockpile)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0010415 .

obo:VO_0016181 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0016588 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016585 .

obo:VO_0007031 a rdfs:Class ;
  rdfs:label "PADRE-CMV fusion peptide vaccine" ;
  rdfs:comment "A peptide-based vaccine containing a pan HLA DR-binding epitope (PADRE) fused to a cytomegalovirus (CMV) peptide epitope, with potential anti-viral and immunomodulating activities. Upon administration, PADRE-CMV fusion peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against CMV in the CMV-infected host. The synthetic peptide PADRE is a universal helper T cell epitope." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:NCBITaxon_1485 a rdfs:Class ;
  rdfs:label "Clostridium" ;
  rdfs:subClassOf obo:NCBITaxon_1239 .

obo:VO_0000465 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus bacterin vaccine" ;
  rdfs:comment "a S. aureus vaccine that uses bacterin as the protective antigen. " ;
  rdfs:subClassOf obo:VO_0002502 .

obo:VO_0016139 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0019890 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Afluria 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019889 , obo:VO_0020301 .

obo:VO_0001638 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.04)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0000526 a rdfs:Class ;
  rdfs:label "rPA with adjuvant nanoemulsion vaccine" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0018138 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Vaccine 35000 PFU/ML / Rubella virus 1400 PFU/ML / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0018136 , obo:VO_0018137 .

obo:VO_0010390 a rdfs:Class ;
  rdfs:label "Quadracel (inactivated poliovirus component grown in MRC-5 cells) vaccine" ;
  rdfs:subClassOf obo:VO_0010736 .

obo:VO_0016802 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] Box of 5" ;
  rdfs:subClassOf obo:VO_0016725 , obo:VO_0016744 , obo:VO_0016823 .

obo:VO_0015819 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015598 .

obo:VO_0015476 a rdfs:Class ;
  rdfs:label "Plasmodium chabaudi protein" ;
  rdfs:subClassOf obo:VO_0010771 .

obo:VO_0001324 a rdfs:Class ;
  rdfs:label "Matrix-S vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0001358 .

obo:VO_0003911 a rdfs:Class ;
  rdfs:label "Fluad 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000362 , obo:VO_0004281 , obo:VO_0010432 .

obo:VO_0005084 a rdfs:Class ;
  rdfs:label "KCONVAC vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated virus vaccine by Shenzhen Kangtai Biological Products and Beijing Minhai Biotechnology Co." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0000984 a rdfs:Class ;
  rdfs:label "Tetanus Toxoid vaccine (for Boost use Only) by Sanofi Pasteur Inc" ;
  rdfs:comment "a tetanus vaccine manusfactured by Sanofi Pasteur Inc. that is only for booster use (not recommended for primary immunization)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010436 .

obo:VO_0018697 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 700000 PFU Powder for Oral Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018693 .

obo:VO_0001173 a rdfs:Class ;
  rdfs:label "pTargeTomp31 vaccine" ;
  rdfs:comment "pTargeTomp31 is a B. melitensis DNA vaccine expressing Omp31  that uses the pTargeT mammalian expression system vector (Promega, USA)." ;
  rdfs:subClassOf obo:VO_0000325 .

obo:VO_0020253 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0003339 .

obo:VO_0005804 a rdfs:Class ;
  rdfs:label "Giardia lamblia vaccine encoding a1-giardin" ;
  rdfs:comment "A Live attenuated vaccine encoding a1-giardin that immunizes against Giardi lamblia trophozoite." ;
  rdfs:subClassOf obo:VO_0001083 .

obo:VO_0019908 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluzone 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020481 .

obo:VO_0015851 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] by Waymade" ;
  rdfs:subClassOf obo:VO_0015644 .

obo:VO_0007208 a rdfs:Class ;
  rdfs:label "Adenovirus-mediated Human Interleukin-12 Vaccine" ;
  rdfs:comment "A replication incompetent adenovirus encoding human pro-inflammatory cytokine interleukin-12 (IL-12) (Ad.hIL-12), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration, the adenovirus selectively infects and replicates in tumor cells, which may result in tumor cell lysis. Synergistically, IL-12 expressed by the adenovirus may activate the immune system by promoting the activation of natural killer cells (NKs), inducing secretion of interferon-gamma and inducing cytotoxic T cell responses against tumor cells, which may result in immune-mediated tumor cell death and inhibition of tumor cell proliferation." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005430 , obo:VO_0007657 .

obo:NCBITaxon_10357 a rdfs:Class ;
  rdfs:label "Betaherpesvirinae" ;
  rdfs:subClassOf obo:NCBITaxon_3044472 .

obo:VO_0019693 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003911 , obo:VO_0019691 .

obo:VO_0011230 a rdfs:Class ;
  rdfs:label "MSP1 from P. vivax" ;
  rdfs:comment "Immunization of BALB/c mice and Aotus monkeys with PvMSP-1 induced IgG antibodies (titer > 10(6)) that cross-reacted with P. vivax parasites. Immunized monkeys displayed partial protection against a challenge with P. vivax blood stages [PubMed: 16291762]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015473 .

obo:VO_0002490 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Haemophilus somnus-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002354 .

obo:VO_0015327 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 , obo:VO_0010451 , obo:VO_0015322 .

obo:VO_0020745 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 120 MG Injectable Solution [Pacis]" ;
  rdfs:subClassOf obo:VO_0020743 , obo:VO_0020744 , obo:VO_0020754 .

obo:VO_0017145 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0017129 , obo:VO_0017605 .

obo:VO_0000008 a rdfs:Class ;
  rdfs:label "vaccine-induced lymphocyte activation" ;
  rdfs:subClassOf obo:VO_0000361 .

obo:VO_0016272 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015923 .

obo:VO_0019762 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:VO_0002283 a rdfs:Class ;
  rdfs:label "Newcastle Disease-Bronchitis Mass & Ark Types, Killed Virus Vaccine-Salmonella Enteritidis Bacterin (USDA: 48D7.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002453 , obo:VO_0007748 .

obo:VO_0015850 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015644 .

obo:VO_0015031 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection [Varivax]" ;
  rdfs:subClassOf obo:VO_0015030 .

obo:VO_0005177 a rdfs:Class ;
  rdfs:label "gorilla adenovirus vector" ;
  rdfs:comment "an adenovirus vaccine vector that uses a gorilla adenovirus." ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0018727 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0018719 , obo:VO_0018724 .

obo:VO_0007608 a rdfs:Class ;
  rdfs:label "gp100:209-217(210M) peptide vaccine" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0019832 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010433 .

obo:VO_0000807 a rdfs:Class ;
  rdfs:label "toxoid vaccine role" ;
  rdfs:comment "A vaccine role that indicates the vaccine being a toxoid vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0003207 a rdfs:Class ;
  rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003200 .

obo:VO_0012165 a rdfs:Class ;
  rdfs:label "Infectious Hematopoietic Necrosis Virus vaccine" ;
  rdfs:comment "A vaccine that protects against Infectious Hematopoietic Necrosis Virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0018600 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 2840000 UNT" ;
  rdfs:subClassOf obo:VO_0004823 .

obo:VO_0020043 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Afluria 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020299 .

obo:VO_0020339 a rdfs:Class ;
  rdfs:label "Flulaval 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000043 , obo:VO_0010416 .

obo:VO_0007158 a rdfs:Class ;
  rdfs:label "pTVG-HP Plasmid DNA Vaccine" ;
  rdfs:comment "A cancer vaccine containing plasmid DNA encoding human prostatic acid phosphatase (PAP) (pTVG-HP) with potential immunostimulatory and antineoplastic activities. Upon administration, pTVG-HP plasmid DNA vaccine may stimulate the host immune system to generate a cytotoxic T lymphocyte (CTL) response against PAP-expressing prostate cancer cells. PAP or prostatic specific acid phosphatase (PSAP) is a tumor associated antigen (TAA) that may be overexpressed in prostate cancer." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0004216 a rdfs:Class ;
  rdfs:label "obsolete BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS 0.1 MG/ML [Biothrax]" .

obo:GO_0071735 a rdfs:Class ;
  rdfs:label "IgG immunoglobulin complex" ;
  rdfs:comment "A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ;
  rdfs:subClassOf obo:GO_0019814 .

obo:VO_0004439 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine VR1012/mPmel17" ;
  rdfs:comment "Gene name: Pmel17" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0018227 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018251 .

obo:VO_0005394 a rdfs:Class ;
  rdfs:label "Synthetic MVA-based SARS-CoV-2 Vaccine COH04S1" ;
  rdfs:comment "A synthetic modified vaccinia Ankara (MVA)-based SARS-CoV-2 vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0010321 a rdfs:Class ;
  rdfs:label "Bordetella Pertussis Filamentous Haemagglutinin Antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0016613 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0016594 .

obo:VO_0002030 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis-Fowl Pox-Mycoplasma Gallisepticum Live Fowl Pox Vector, Live Virus Vaccine (USDA:1D61.R0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002328 , obo:VO_0007748 .

obo:VO_0017361 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0004556 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda DNA vaccine pCE18" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002506 .

obo:VO_0019588 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019584 , obo:VO_0020489 .

obo:VO_0004400 a rdfs:Class ;
  rdfs:label "Glypican-3-derived peptide vaccine for human hepatocellular carcinoma" ;
  rdfs:comment "An autologous dendritic cell vaccine with potential immunostimulatory activity. Dendritic cells harvested from a prostate cancer patient are transfected with the mRNA encoding for prostate specific antigen (PSA), a tumor marker secreted by prostatic epithelial and ductal cells. When reintroduced back to the patient, these PSA RNA pulsed autologous dendritic cells may elicit a cytotoxic T-cell (CTL) response against PSA-positive prostate cancer cells. " ;
  rdfs:subClassOf obo:VO_0005499 , obo:VO_0007657 .

obo:VO_0000733 a rdfs:Class ;
  rdfs:label "CVD 1204(pGA1-CS2) vaccine" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0002204 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, C2 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1XC1.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0010900 a rdfs:Class ;
  rdfs:label "BoNT/A1 from C. botulinum" ;
  rdfs:comment "A single dose of ciBoNT/A1 HP provided equivalent or greater protective immunity, not only against the homologous toxin, but also against two distinct toxin subtypes with significant amino acid divergence in mice when challenged with BoNT/A subtypes /A1, /A2, and /A3 from Clostridium botulinum [PubMed: 19450643]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010762 .

obo:VO_0019803 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0003706 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2017-2018 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003704 .

obo:VO_0011048 a rdfs:Class ;
  rdfs:label "FlaC" ;
  rdfs:comment "Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model.  All three proteins were immunogenic, FlaC provided an 18% protection against disease from C. jejuni 81-176 [PubMed: 18426878]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010765 .

obo:VO_0015143 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015141 .

obo:VO_0021140 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0004450 a rdfs:Class ;
  rdfs:label "Prostate cancer DNA vaccine PSCA-HSP encoding PSCA and HSP" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0000379 a rdfs:Class ;
  rdfs:label "intravaginal vaccination" ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0002781 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis fadD26 mutant vaccine" ;
  rdfs:comment "An fadD26 mutant is attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0020740 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain Injection" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017679 .

obo:VO_0015663 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015597 .

obo:VO_0015888 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 50" ;
  rdfs:subClassOf obo:VO_0015619 , obo:VO_0016006 .

obo:VO_0010952 a rdfs:Class ;
  rdfs:label "FbpA" ;
  rdfs:comment "Researchers have developed DNA vaccines expressing M. tuberculosis antigen 85A (Ag85A, fbpA) and cytokine granulocyte macrophage colony stimulating factor (GM-CSF).  The immune strategy of BCG-prime and DNA vaccine boost induced mice to generate efficient immune protection against M. tuberculosis challenge [PubMed: 19450898]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0003566 a rdfs:Class ;
  rdfs:label "PNEUMOVAX 23 vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003563 .

obo:VO_0015881 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015618 , obo:VO_0016002 .

obo:VO_0016090 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015992 .

obo:VO_0018444 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumopur] Box of 1" ;
  rdfs:subClassOf obo:VO_0018424 .

obo:VO_0001050 a rdfs:Class ;
  rdfs:label "pseudorabies virus strain Bartha vaccine vector" ;
  rdfs:comment "A herpesevirus vaccine vector that uses an established live-virus vaccine against Aujeszky's disease of swine, pseudorabies virus (PrV) strain Bartha (PrV-Ba), to serve as vector." ;
  rdfs:subClassOf obo:VO_0000283 .

obo:VO_0020612 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0021023 .

obo:VO_0015942 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015638 , obo:VO_0015716 , obo:VO_0016040 .

obo:VO_0004215 a rdfs:Class ;
  rdfs:label "Biothrax Injectable Product" ;
  rdfs:subClassOf obo:VO_0000014 .

obo:VO_0020130 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020131 .

obo:VO_0004904 a rdfs:Class ;
  rdfs:label "Influenza A virus (A/Indonesia/05/2005) antigen" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0017204 a rdfs:Class ;
  rdfs:label "1 ML tetanus toxoid vaccine, inactivated 2000 IU/ML Injectable Solution by SK Chemical" ;
  rdfs:subClassOf obo:VO_0017203 .

obo:VO_0002956 a rdfs:Class ;
  rdfs:label "Equid herpesvirus gI mutant vaccine" ;
  rdfs:comment "A glycoprotein I mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice" ;
  rdfs:subClassOf obo:VO_0001486 .

obo:VO_0017182 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetasorbat] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017179 .

obo:VO_0000285 a rdfs:Class ;
  rdfs:label "pND DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0011284 a rdfs:Class ;
  rdfs:label "P36/LACK" ;
  rdfs:comment "BALB/c mice immunized with a DNA vector expressing p36/LACK of Leishmania infantum followed by a booster with VVp36/LACK induced significant protection against Leishmania major infection [PubMed: 11489418]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010836 .

obo:VO_0000957 a rdfs:Class ;
  rdfs:label "Brucella abortus recombinant vector vaccine" ;
  rdfs:comment "a B. abortus vaccine that uses a recombinant vector. " ;
  rdfs:subClassOf obo:VO_0000108 , obo:VO_0000484 .

obo:VO_0001432 a rdfs:Class ;
  rdfs:label "Feline herpesvirus 1 gene" ;
  rdfs:comment "A viral gene that is from Feline herpesvirus 1." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0000323 a rdfs:Class ;
  rdfs:label "Brucella abortus conjugate vaccine using L7/L12" ;
  rdfs:subClassOf obo:VO_0000956 .

obo:VO_0005251 a rdfs:Class ;
  rdfs:label "COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey" ;
  rdfs:comment "A COVID-19 virus-like particle vaccine developed by the Scientific and Technological Research Council of Turkey" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005205 .

obo:VO_0002902 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium ompR mutant vaccine" ;
  rdfs:comment "An ompR mutant is attenuated in mice after oral challenge. Twenty eight days after immunization, mice were challenged with wild type S. typhimurium and were significantly protected" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0016627 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0016606 , obo:VO_0016613 .

obo:VO_0019722 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0017252 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0021180 a rdfs:Class ;
  rdfs:label "Fluzone High-Dose 2010-2011 vaccine" ;
  rdfs:subClassOf obo:VO_0000079 , obo:VO_0010426 .

obo:VO_0007262 a rdfs:Class ;
  rdfs:label "anti-idiotype MUC-1 monoclonal antibody vaccine" ;
  rdfs:comment "A monoclonal antibody that functionally mimics MUC-1 antigen, a tumor cell surface antigen. Administration of anti-idiotype MUC-1 monoclonal antibody may elicit an anti-idiotype antibody and corresponding T-cell response against MUC-1 expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0020099 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.0000000385 MG/ML" ;
  rdfs:subClassOf obo:VO_0003949 .

obo:VO_0020685 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML Injectable Suspension [INFLUVAC] Box of 1" ;
  rdfs:subClassOf obo:VO_0020684 , obo:VO_0020686 .

obo:VO_0020044 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Agriflu 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0001176 , obo:VO_0004914 , obo:VO_0020307 .

obo:VO_0004389 a rdfs:Class ;
  rdfs:label "Marburg virus DNA prime/boost vaccine DNA/rAd5-GP encoding GP from strain Angola" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012163 .

obo:VO_0010766 a rdfs:Class ;
  rdfs:label "Escherichia coli protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0005509 a rdfs:Class ;
  rdfs:label "IL-12-MOP (CTX-1796) vaccine adjuvant" ;
  rdfs:comment "Nucleic acid vaccine adjuvant that targets on cytokine receptor to induce a Th1-based response." ;
  rdfs:subClassOf obo:VO_0006109 .

obo:VO_0003362 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen" ;
  rdfs:subClassOf obo:VO_0003960 .

obo:VO_0018926 a rdfs:Class ;
  rdfs:label "influenza B virus B/Austria/1359417/2021 antigen" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:NCBITaxon_79668 a rdfs:Class ;
  rdfs:label "Clostridium perfringens C" ;
  rdfs:subClassOf obo:NCBITaxon_1502 .

obo:VO_0017066 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0017061 , obo:VO_0017543 .

obo:VO_0019985 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Agriflu 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019972 .

obo:NCBITaxon_77054 a rdfs:Class ;
  rdfs:label "Theileria lestoquardi" ;
  rdfs:subClassOf obo:NCBITaxon_5873 .

obo:VO_0015104 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015094 , obo:VO_0015260 .

obo:VO_0017156 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017153 .

obo:VO_0004792 a rdfs:Class ;
  rdfs:label "rMVA-SIV-CD40L human immunodeficiency virus vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0018769 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017799 .

obo:VO_0011338 a rdfs:Class ;
  rdfs:label "TSA from Trypanosoma brucei" ;
  rdfs:comment "BALB-c mice immunized intramuscularly with a single dose (100 microg) of a plasmid DNA encoding the 5'-terminal region of the trans-sialidase (nTSA) gene of T. brucei brucei are able to produce IgG antibodies that bind to the bloodstream form of T. brucei-protein extract and recognize the recombinant nTSA protein, expressed in Escherichia coli. Furthermore, this DNA vaccination process was able to protect 60% of mice submitted to a challenge assay with the infective form of T. brucei brucei parasites [PubMed: 19582478]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010854 .

obo:VO_0002253 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4844.30)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002428 , obo:VO_0007748 .

obo:VO_0011499 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae Hap protein vaccine" ;
  rdfs:subClassOf obo:VO_0012185 .

obo:VO_0020515 a rdfs:Class ;
  rdfs:label "0.1 ML BCG, Live, Connaught Strain 1 MG/ML Injectable Solution by Sanofi" ;
  rdfs:subClassOf obo:VO_0020514 .

obo:VO_0018404 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 18C vaccine 0.006 MG/ML" ;
  rdfs:subClassOf obo:VO_0003222 .

obo:VO_0005260 a rdfs:Class ;
  rdfs:label "COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0005093 a rdfs:Class ;
  rdfs:label "QazVac vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine manufactured by the Research Institute for Biological Safety Problems (Republic of Kazakhstan)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0016596 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0016584 .

obo:VO_0007527 a rdfs:Class ;
  rdfs:label "monoclonal antibody 4B5 anti-idiotype vaccine" ;
  rdfs:comment "A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2 with potential immunostimulating and antineoplastic activities. Upon administration, monoclonal antibody 4B5 anti-idiotype vaccine may elicit both cellular and humoral immune responses against GD2- expressing tumor cells. GD2 is a glycosphingolipid (ceramide and oligosaccharide) that may be highly expressed by melanomas and other neuroectodermal tumors, while only minimally expressed by normal tissues." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0007277 a rdfs:Class ;
  rdfs:label "autologous anti-mart-1 f5 T-cell receptor gene-engineered peripheral blood lymphocytes vaccine" ;
  rdfs:comment "Human autologous peripheral blood lymphocytes (PBLs) transduced with a melanoma antigen MART-1 epitope-determined T cell receptor (TCR) gene, with potential antineoplastic activity. PBLs are isolated from a melanoma patient and pulsed with a viral vector that encodes the TCR specific for an epitope of MART-1 (F5 TCR). After expansion ex vivo, the transduced autologous PBLs, expressing this specific TCR, are reintroduced into the patient, and bind to melanoma cells expressing the MART-1 antigen, which may result in specific cytotoxic T-lymphocyte (CTL) killing of MART-1-expressing melanoma cells. MART-1 (melanoma antigen recognized by T cells 1), also known as Melan-A, is a melanocyte lineage-specific transmembrane protein." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0003470 a rdfs:Class ;
  rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0002372 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Vaccine" ;
  rdfs:subClassOf obo:VO_0001507 , obo:VO_0002345 .

obo:VO_0020474 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0020470 .

obo:VO_0017842 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide Injection [Mengivac A + C]" ;
  rdfs:subClassOf obo:VO_0017893 .

obo:DOID_0050746 a rdfs:Class ;
  rdfs:label "mantle cell lymphoma"@en ;
  rdfs:comment "A B-cell lymphocytic neoplasm due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles."@en ;
  rdfs:subClassOf obo:DOID_707 .

obo:VO_0005334 a rdfs:Class ;
  rdfs:label "SII Bivalent vaccine" ;
  rdfs:comment "A SARS-CoV-2 bivalent protein subunit vaccine by Novavax containing antigen for both the ancestral strain and B.1.351 (Beta) variant." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0016479 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Mevita" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0005039 a rdfs:Class ;
  rdfs:label "pRC DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pRC.  This plasmid is 7400 base pairs in length and contains CMV and RSV promoters." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016231 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015906 .

obo:VO_0019878 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Fluzone Quadrivalent 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003579 .

obo:VO_0019321 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0010949 a rdfs:Class ;
  rdfs:label "Gag protein from SIV-mnd 2" ;
  rdfs:comment "A novel primate lentivirus was identified in Mandrillus sphinx. One of the newly isolated SIV strains was intravenously inoculated into two rhesus macaques and resulted in chronic infection. These SIVs do not cluster with SIVmndGB1, the former representative strain of SIVmnd, but form a new, independent lineage. These results indicate that these SIVmnds are a novel type of SIVmnd and have infected Cameroonian mandrills for a long time. To date, M. sphinx is the only primate species other than humans that is naturally infected with two different types of SIV [PubMed: 11522184]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010767 .

obo:VO_0003802 a rdfs:Class ;
  rdfs:label "Varicella zoster virus glycoprotein E, recombinant" ;
  rdfs:comment "RXAUI: 9698275" ;
  rdfs:subClassOf obo:VO_0003801 .

obo:VO_0017327 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000943 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0020150 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML [Menquadfi]" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0017815 .

obo:VO_0016516 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0010480 a rdfs:Class ;
  rdfs:label "licensed human rheumatic fever vaccine" ;
  rdfs:comment "Rheumatic fever vaccine that is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0006049 .

obo:NCBITaxon_10319 a rdfs:Class ;
  rdfs:label "Varicellovirus" ;
  rdfs:subClassOf obo:NCBITaxon_10293 .

obo:VO_0001342 a rdfs:Class ;
  rdfs:label "IL-15 vaccine adjuvant" ;
  rdfs:comment "A cytokine vaccine adjuvant that uses the adjuvant effect of cytokine IL-15." ;
  rdfs:subClassOf obo:VO_0001353 .

obo:VO_0005322 a rdfs:Class ;
  rdfs:label "AG0302-COVID19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 DNA vaccine developed by AnGes, named as AG0302-COVID19." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0000327 a rdfs:Class ;
  rdfs:label "pUC19 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0020213 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.025 MG/ML" ;
  rdfs:subClassOf obo:VO_0020498 .

obo:VO_0020941 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus antigen Nasal Spray" ;
  rdfs:subClassOf obo:VO_0020018 .

obo:VO_0007222 a rdfs:Class ;
  rdfs:label "Allogeneic Glioblastoma Stem-like Cell Line Lysate-pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from an allogeneic glioblastoma (GBM) stem-like cell line, with potential immunostimulatory and antineoplastic activities. Upon administration allogeneic glioblastoma stem-like cell line lysate-pulsed autologous dendritic cell vaccine exposes the immune system to GBM stem cell antigens, which may result in cytotoxic T lymphocyte (CTL) and antibody responses against GBM cells. This leads to GBM cell lysis. GBM stem-like cells contain a specific range of antigens that are essential for the neoplastic growth and survival of GBM cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0004914 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0016696 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0001938 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Mannheimia Haemolytica Bacterin (USDA: 44A5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002357 .

obo:NCBITaxon_1678143 a rdfs:Class ;
  rdfs:label "Paslahepevirus balayani" ;
  rdfs:subClassOf obo:NCBITaxon_2732543 .

obo:VO_0005284 a rdfs:Class ;
  rdfs:label "NanoVax/NE01 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0007446 a rdfs:Class ;
  rdfs:label "human papillomavirus  18 E6:13-21 peptide vaccine" ;
  rdfs:comment "A synthetic peptide vaccine consisting of amino acids 13 through 21 of the viral oncoprotein human papillomavirus (HPV) 18 E6. The HPV 18E6 peptide cross-reacts immunologically with both HPV type 16 and HPV type 18, the most common HPV types involved in cervical cancer. Vaccination with HPV-18 E6:13-21 peptide may stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV 16 and 18." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0015247 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015246 , obo:VO_0015248 .

obo:VO_0018149 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 40" ;
  rdfs:subClassOf obo:VO_0018144 , obo:VO_0018159 .

obo:VO_0017279 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0017276 .

obo:VO_0019862 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluarix Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020319 .

obo:VO_0016419 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015967 .

obo:VO_0000054 a rdfs:Class ;
  rdfs:label "IPOL vaccine" ;
  rdfs:comment "IPOL, Poliovirus Vaccine Inactivated is a sterile suspension of three types of poliovirus: Type 1 (Mahoney), Type 2 (MEF-1), and Type 3 (Saukett). IPOL vaccine is a highly purified, inactivated poliovirus vaccine with enhanced potency." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000664 , obo:VO_0000712 , obo:VO_0010447 .

obo:VO_0006097 a rdfs:Class ;
  rdfs:label "2G023A vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant which is a small molecule TLR agonist that drives a mixed Th1/Th2 response." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0016747 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 10" ;
  rdfs:subClassOf obo:VO_0016712 , obo:VO_0016768 .

obo:VO_0019462 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 4 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0001421 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium gene" ;
  rdfs:comment "A bacterial gene that is from Salmonella Typhimurium." ;
  rdfs:subClassOf obo:VO_0000168 .

obo:VO_0000491 a rdfs:Class ;
  rdfs:label "active immunization" ;
  rdfs:comment "An immunization that involves the introduction of foreign molecules into a recipient body, in a way which causes the recipient to actively induce adaptive immunity against the immunization target." ;
  rdfs:subClassOf obo:VO_0000490 .

obo:VO_0011494 a rdfs:Class ;
  rdfs:label "Theileria parva Subunit p67 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0001061 .

obo:VO_0003215 a rdfs:Class ;
  rdfs:label "seasonal Influenza A27:H29 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0005244 a rdfs:Class ;
  rdfs:label "Soberana Plus vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Instituto Finlay de Vacunas. It is used as a booster dose for the Soberana 02 COVID-19 vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0015537 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution [Hepasorbat]" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0003894 a rdfs:Class ;
  rdfs:label "Flublok 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000978 , obo:VO_0010433 .

obo:VO_0017084 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017561 .

obo:VO_0018473 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 10 by Axicorp" ;
  rdfs:subClassOf obo:VO_0018455 .

obo:VO_0017215 a rdfs:Class ;
  rdfs:label "50 ML tetanus toxoid vaccine, inactivated 1.5 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017466 .

obo:VO_0000094 a rdfs:Class ;
  rdfs:label "RabAvert vaccine" ;
  rdfs:comment "RabAvert Rabies Vaccine is a sterile, freeze-dried vaccine obtained by growing the fixed-virus strain Flury Low Egg Passage (LEP) in primary cultures of chicken fibroblasts." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000650 , obo:VO_0000714 , obo:VO_0010448 .

obo:VO_0019379 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Vaxelis]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0005470 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0012185 .

obo:VO_0005204 a rdfs:Class ;
  rdfs:label "COVID-19 live, attenuated vaccine" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0004908 .

obo:VO_0002073 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Standard & Variant, Mass Type, Killed Virus Vaccine (USDA: 12J5.61)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002367 , obo:VO_0007748 .

obo:VO_0011402 a rdfs:Class ;
  rdfs:label "Seoul virus vaccine rCAV-2-Gc" ;
  rdfs:subClassOf obo:VO_0012167 .

obo:VO_0020882 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Xanaflu]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020902 .

obo:VO_0007535 a rdfs:Class ;
  rdfs:label "fowlpox virus vaccine" ;
  rdfs:comment "A recombinant virus-based vaccine that contains various peptide antigens. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues. Strong CD8 T cell responses may be induced after prolonged immunization and have been associated with tumor regression." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0016360 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:VO_0018680 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML [Rotarix]" ;
  rdfs:subClassOf obo:VO_0010738 , obo:VO_0018679 .

obo:OPL_0000357 a rdfs:Class ;
  rdfs:label "Sarcocystis neurona merozoite stage" ;
  rdfs:comment "A merozoite stage in the Sarcocystis neurona life cycle." ;
  rdfs:subClassOf obo:OPL_0000036 , obo:OPL_0000379 .

obo:VO_0004599 a rdfs:Class ;
  rdfs:label "Human cytomegalovirus DNA vaccine pcGB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001227 .

obo:OPL_0000035 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum erythrocytic schizont stage" ;
  rdfs:comment "An erythrocytic schizont stage in the Plasmodium falciparum lifecycle that occurs in the infected erythrocytes of a human host." ;
  rdfs:subClassOf obo:OPL_0000078 , obo:OPL_0000158 , obo:OPL_0000298 .

obo:VO_0007702 a rdfs:Class ;
  rdfs:label "multipeptide XS15 vaccine" ;
  rdfs:comment "A cancer vaccine adjuvant and synthetic Toll-like receptor (TLR) type 1 and 2 ligand composed of a lipopeptide containing a water-soluble derivative of Pam3-Cys, the biologically active component of the mycobacterial 19 kDa lipoprotein of mycobacteria, that is covalently linked to a synthetic peptide (GDPKHPKSF), with potential immunostimulating activity. TLR1/2 agonist Pam3Cys-GDPKHPKSF targets, binds to and activates TLR1/2, which induces CD8- and T-helper 1 CD4-positive T-cell responses. This may enhance T-cell-mediated immune responses when administered together with peptide vaccine. A multi-peptide vaccine can be used in combination with the TLR1/2 ligand XS15 in CLL patients undergoing ibrutinib-based regimes. Applying several CLL-associated antigens simultaneously increases the likelihood that a multi-clonal, broad and at the same time highly specific T-cell response is mounted, thereby preventing potential tumor escape mechanisms. The novel TLR1/2 ligand (XS15, developed in Tübingen) that (i) is water-soluble and (ii) GMP-amenable, (iii) non-toxic and (iv) effective in inducing T cells specific for peptides in vivo. A personalized multi-peptide vaccination can also be used in combination with the TLR1/2 ligand XS15 for individual patients with advanced solid and hematological malignancies without any approved treatment options. " ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0004037 a rdfs:Class ;
  rdfs:label "Ebola virus EBOV NP vaccine" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0016052 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0003259 .

obo:VO_0020089 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine Nasal Spray" ;
  rdfs:subClassOf obo:VO_0003497 , obo:VO_0004914 .

obo:VO_0003775 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003773 .

obo:VO_0004422 a rdfs:Class ;
  rdfs:label "VEE virus recombinant vector vaccine RAd/VEEV" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0001499 .

obo:VO_0007299 a rdfs:Class ;
  rdfs:label "autologous HNSCC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine" ;
  rdfs:comment "A vaccine consisting of lethally irradiated human fetal lung fibroblasts (Medical Research Council 5 or MRC-5) transfected with autologous tumor DNA derived from a head and neck squamous cell carcinoma (HNSCC), with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, the autologous HNSCC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine expresses HNSCC tumor-associated antigens (TAAs), which may activate the immune system to induce a cytotoxic T-lymphocyte (CTL) response against HNSCC cells. The MRC-5 cell line, established in 1966, is a human diploid lung fibroblast cell line derived from the human lung tissue of a 14-week-old male fetus." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005497 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0010017 a rdfs:Class ;
  rdfs:label "Leishmania  donovani HASPB1" ;
  rdfs:comment "A HASPB1 protein that is part of Leishmania  donovani" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0015953 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat] Box of 10" ;
  rdfs:subClassOf obo:VO_0015641 , obo:VO_0015727 , obo:VO_0016040 .

obo:VO_0005323 a rdfs:Class ;
  rdfs:label "authorized COVID-19 DNA vaccine" ;
  rdfs:subClassOf obo:VO_0005203 , obo:VO_0005264 .

obo:VO_0003936 a rdfs:Class ;
  rdfs:label "GARDASIL Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003932 .

obo:VO_0001690 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 16L1.06)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0017625 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetasorbat] Box of 10" ;
  rdfs:subClassOf obo:VO_0017624 , obo:VO_0017626 .

obo:VO_0003891 a rdfs:Class ;
  rdfs:label "Flublok 2016-2017 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003890 .

obo:VO_0010061 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi PkMSP1p42" ;
  rdfs:comment "A PkMSP1 protein that is part of Plasmodium knowlesi|A PkMSP1p42 protein that is part of Plasmodium knowlesi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015472 .

obo:VO_0006067 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine UNSPECIFIED" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005264 .

obo:VO_0018162 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 25000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018244 .

obo:VO_0006017 a rdfs:Class ;
  rdfs:label "licensed human hepatitis E vaccine" ;
  rdfs:subClassOf obo:VO_0000609 , obo:VO_0000635 .

obo:VO_0007272 a rdfs:Class ;
  rdfs:label "Apoptotic Autologous Tumor Cells-pulsed Alpha-type-1 Polarized Dendritic Cells Vaccine" ;
  rdfs:comment "A cell based cancer vaccine composed of mature polarized dendritic cells (DCs) and pulsed with apoptotic autologous tumor cells that has potential immunostimulating and antineoplatic activities. Dendritic cells (DCs) were treated with interleukin-1beta, tumor necrosis factor alpha, interferon-alpha (IFN-a), IFN-gamma and polyinosinic:polycytidylic acid (p-I:C) to produce mature alpha type-1 polarized DCs (alphaDC1) that are capable of producing high levels of interleukin-12p70 (IL-12p70). The alphaDC1 are subsequently pulsed with apoptotic autologous tumor cells. Upon administration, these DCs are able to induce a potent cytotoxic T lymphocyte (CTL) response against tumor associated antigens (TAAs), resulting in tumor cell lysis and inhibition of tumor cell growth. Apoptotic tumor cells contain an array of TAAs" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0000245 a rdfs:Class ;
  rdfs:label "edibility" ;
  rdfs:comment """A physical quality inhering in a bearer by virtue of the bearer being fit
to be eaten.""" ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:VO_0019612 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluarix Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020321 .

obo:VO_0010077 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi TcENO" ;
  rdfs:comment "A TcENO protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0002301 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.23)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002479 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0000606 a rdfs:Class ;
  rdfs:label "delta ureC hly+ rBCG vaccine" ;
  rdfs:subClassOf obo:VO_0001466 , obo:VO_0003130 .

obo:VO_0004728 a rdfs:Class ;
  rdfs:label "ALVAC-RV vaccine" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0007309 a rdfs:Class ;
  rdfs:label "Autologous NSCLC Peptide-specific Dendritic Cell Vaccine" ;
  rdfs:comment "A personalized cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with immunogenic peptides derived from autologous non-small cell lung cancer (NSCLC) cells, with potential immunostimulating and antineoplastic activities. During leukapheresis, mature DCs are loaded with autologous NSCLC-derived peptides. Upon re-administration of the NSCLC peptide-specific DC vaccine, the immune system is exposed to NSCLC-associated antigens. This results in the induction of a specific cytotoxic T-lymphocyte (CTL) response against NSCLC cells and tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:NCBITaxon_83334 a rdfs:Class ;
  rdfs:label "Escherichia coli O157:H7" ;
  rdfs:subClassOf obo:NCBITaxon_562 .

obo:VO_0002237 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46P9.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002405 , obo:VO_0007748 .

obo:VO_0016682 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Dipht Toxoid Asid]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0019121 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2016 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020488 .

obo:VO_0010327 a rdfs:Class ;
  rdfs:label "hepatitis B virus subtype ADW2 HBsAg surface protein antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:NCBITaxon_6334 a rdfs:Class ;
  rdfs:label "Trichinella spiralis" ;
  rdfs:subClassOf obo:NCBITaxon_119088 .

obo:VO_0020605 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020603 .

obo:VO_0015577 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0015493 , obo:VO_0015539 , obo:VO_0015540 .

obo:VO_0015995 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 25" ;
  rdfs:subClassOf obo:VO_0015659 , obo:VO_0015780 .

obo:VO_0018008 a rdfs:Class ;
  rdfs:label "Human poliovirus 160 BAU/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 .

obo:VO_0020842 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Grippe-Impfstoff Stada]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0020425 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typhim VI] Box of 1" ;
  rdfs:subClassOf obo:VO_0020430 , obo:VO_0020470 .

obo:VO_0003854 a rdfs:Class ;
  rdfs:label "Typhim Vi 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003853 .

obo:VO_0010742 a rdfs:Class ;
  rdfs:label "Tripacel vaccine" ;
  rdfs:subClassOf obo:VO_0000714 , obo:VO_0000738 .

obo:VO_0017798 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine Injectable Solution [Pertuvac]" ;
  rdfs:subClassOf obo:VO_0017808 .

obo:VO_0019585 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Flublok 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003886 , obo:VO_0010427 , obo:VO_0019584 .

obo:VO_0021162 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:NCBITaxon_114727 a rdfs:Class ;
  rdfs:label "H1N1 subtype" ;
  rdfs:subClassOf obo:NCBITaxon_11320 .

obo:VO_0018868 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:OPL_0000417 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Plasmodium knowlesi." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0004754 a rdfs:Class ;
  rdfs:label "BV-GD-ORF2 vaccine" ;
  rdfs:subClassOf obo:VO_0001524 .

obo:VO_0000623 a rdfs:Class ;
  rdfs:label "DNA vaccine role" ;
  rdfs:comment "A vaccine role that indicates the vaccine being a DNA vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0002967 a rdfs:Class ;
  rdfs:label "Gallid herpesvirus 1 UL23 mutant vaccine" ;
  rdfs:comment "A thymidine-kinase mutant is attenuated in chickens and induced protection from challenge with wild type GHV-1" ;
  rdfs:subClassOf obo:VO_0001488 .

obo:VO_0005314 a rdfs:Class ;
  rdfs:label "Th1/Th17 mixed immune profile" ;
  rdfs:comment "An immune profile that is characterized by the presense of both Type 1 and Type 17 T helper  (Th1 and Th17) cells." ;
  rdfs:subClassOf obo:VO_0005308 .

obo:VO_0011519 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus DNA vaccine encoding DnaX" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001085 .

obo:VO_0010170 a rdfs:Class ;
  rdfs:label "hepatitis A and hepatitis B vaccine, pediatric/adolescent (non-US)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000745 .

obo:VO_0003650 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2018-2019 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003649 .

obo:VO_0017853 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 2.5 MG" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010289 , obo:VO_0010444 .

obo:VO_0001551 a rdfs:Class ;
  rdfs:label "Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0007748 .

obo:VO_0004475 a rdfs:Class ;
  rdfs:label "Human papillomavirus DNA vaccine hCRTE6E7L2 DNA encoding CRT linked to E6, E7 and L2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000667 .

obo:VO_0010833 a rdfs:Class ;
  rdfs:label "Eimeria maxima protein" ;
  rdfs:subClassOf obo:VO_0010822 .

obo:VO_0001161 a rdfs:Class ;
  rdfs:label "challenge dose specification" ;
  rdfs:subClassOf obo:OBI_0000969 .

obo:VO_0020350 a rdfs:Class ;
  rdfs:label "Flumist 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000044 , obo:VO_0010417 .

obo:VO_0007709 a rdfs:Class ;
  rdfs:label "neoantigen peptide vaccine" ;
  rdfs:comment "A cancer vaccine consisting of patient-specific antigens, which are immunogenic and unique to the patient's tumor, with potential immunomodulating and antineoplastic activities. The neoantigen peptide vaccine, the peptides stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the neoantigens, which results in tumor cell lysis. Personalized neo-antigen peptide vaccine is a product combines multiple patient specific neo-antigens. Given personalized neo-antigen peptide vaccine together with Th1 polarizing adjuvant poly ICLC may induce a polyclonal, poly-epitope, cytolytic T cell immunity against the patient's tumor. Patients also receive nivolumab." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0019933 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003579 .

obo:NCBITaxon_9534 a rdfs:Class ;
  rdfs:label "Chlorocebus aethiops" ;
  rdfs:subClassOf obo:NCBITaxon_9526 .

obo:VO_0015607 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015557 , obo:VO_0015590 , obo:VO_0015654 .

obo:VO_0003165 a rdfs:Class ;
  rdfs:label "J-Vax vaccine" ;
  rdfs:comment "An inactivated Japanese encephalitis vaccine (JVax *) for use by certain travelers to and expatriates in Asia." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010440 .

obo:VO_0019473 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.015 MG/ML / Neisseria meningitidis 0.25 MG/ML [Liquid PedvaxHIB]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003192 , obo:VO_0010437 , obo:VO_0010444 .

obo:VO_0001357 a rdfs:Class ;
  rdfs:label "synthetic vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that contains synthetic material." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0020670 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension [Bcg Medac] Box of 1" ;
  rdfs:subClassOf obo:VO_0020669 , obo:VO_0020751 .

obo:VO_0018433 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II]" ;
  rdfs:subClassOf obo:VO_0018423 .

obo:VO_0002270 a rdfs:Class ;
  rdfs:label "Encephalomyelitis Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4867.21)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000541 , obo:VO_0000640 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0007748 .

obo:VO_0001668 a rdfs:Class ;
  rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.59)" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:VO_0020930 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Agrippal]" ;
  rdfs:subClassOf obo:VO_0020929 .

obo:VO_0020402 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020387 .

obo:VO_0010891 a rdfs:Class ;
  rdfs:label "PmpG-1" ;
  rdfs:comment "Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection.  Overall, vaccination with DCs transfected with PmpG-1(25-500) exhibited the greatest degree of protective immunity among the four Chlamydia Ags tested [PubMed: 19155509]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010795 .

obo:VO_0004320 a rdfs:Class ;
  rdfs:label "Foot and mouth disease DNA vaccine pWRMHX encoding a minimal self-cleaving ribozyme" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001213 .

obo:VO_0018484 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0018442 .

obo:VO_0006088 a rdfs:Class ;
  rdfs:label "Venezuelan equine encephalitis vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0001499 .

obo:VO_0002951 a rdfs:Class ;
  rdfs:label "Bovine respiratory syncytial virus glycoprotein G mutant vaccine" ;
  rdfs:comment "A glycoprotein G deletion in bovine respiratory syncytial virus(rBRSV) and recombinant rBRSV was attenuated and provided protection against a BRSV challenge infection in calves" ;
  rdfs:subClassOf obo:VO_0001466 , obo:VO_0001507 .

obo:VO_0019873 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0004233 a rdfs:Class ;
  rdfs:label "gp120 recominant vaccine with GMDP adjuvant" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0003442 a rdfs:Class ;
  rdfs:label "Acel-Imune vaccine" ;
  rdfs:comment "A DTaP vaccine used to keep up protection (immunity) against diphtheria, tetanus (lockjaw) and pertussis (whooping cough) in children and adults who have been vaccinated for these diseases in the past." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000943 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0020135 a rdfs:Class ;
  rdfs:label "mumps virus vaccine live, Jeryl Lynn strain 40000 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML [Biavax II]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0001220 , obo:VO_0003418 .

obo:VO_0004526 a rdfs:Class ;
  rdfs:label "Murine cytomegalovirus DNA vaccine pgM-pgN" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003062 .

obo:VO_0001589 a rdfs:Class ;
  rdfs:label "avian influenza H10N9 Subtype, Killed Virus Vaccine (USDA: 1057.H0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0004083 a rdfs:Class ;
  rdfs:label "V-LSG/N vaccine" ;
  rdfs:subClassOf obo:VO_0012177 .

obo:VO_0001487 a rdfs:Class ;
  rdfs:label "Feline herpesvirus 1 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Feline herpesvirus 1 (Felid herpesvirus 1) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003537 .

obo:VO_0015526 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0010327 .

obo:VO_0004848 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen 0.12 MG/ML / Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen 0.12 MG/ML [Trumenba]" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0003081 .

obo:VO_0020627 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020623 .

obo:VO_0000406 a rdfs:Class ;
  rdfs:label "AIDSVAX B/E vaccine" ;
  rdfs:subClassOf obo:VO_0000402 , obo:VO_0000455 .

obo:DOID_4947 a rdfs:Class ;
  rdfs:label "cholangiocarcinoma"@en ;
  rdfs:comment "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells."@en ;
  rdfs:subClassOf obo:DOID_4896 .

obo:VO_0007612 a rdfs:Class ;
  rdfs:label "HCA587 protein vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0019551 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003751 , obo:VO_0019544 .

obo:VO_0018342 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG" ;
  rdfs:subClassOf obo:VO_0003335 .

obo:VO_0004921 a rdfs:Class ;
  rdfs:label "human age" ;
  rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ;
  rdfs:subClassOf obo:PATO_0000011 .

obo:VO_0012398 a rdfs:Class ;
  rdfs:label "Sib35" ;
  rdfs:comment "Immunization with Sib 35 enhanced survival rates in mice challenged with a GAS strain, while exhibiting no toxicity in hosts [PubMed: 15990202]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012357 .

obo:VO_0003421 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003415 .

obo:VO_0010815 a rdfs:Class ;
  rdfs:label "Vibrio anguillarum (Listonella anguillarum) protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0017305 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 LFU/ML / Pertussis Vaccine 0.0468 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML [Tripacel]" ;
  rdfs:subClassOf obo:VO_0010742 , obo:VO_0018783 .

obo:VO_0020514 a rdfs:Class ;
  rdfs:label "0.1 ML BCG, Live, Connaught Strain 1 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020699 .

obo:VO_0003168 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Acellular Pertussis-Haemophilus b vaccine" ;
  rdfs:comment "A combination vaccine that protects against diphtheria, tetanus, pertussis, and Haemophilus influenzae type B." ;
  rdfs:subClassOf obo:VO_0000756 , obo:VO_0000942 .

obo:VO_0003840 a rdfs:Class ;
  rdfs:label "PEDIARIX vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003838 .

obo:VO_0020496 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2023 Southern Hemisphere vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010429 .

obo:VO_0019220 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0020323 .

obo:VO_0007714 a rdfs:Class ;
  rdfs:label "OCDC and NeoDC vaccine" ;
  rdfs:comment "A cancer vaccine made with autologous DCs that are pulsed with HOCl-oxidized autologous tumor lysate (OCDC) and administered in prime phase, along with a personal neoantigen-sensitized DC(NeoDC) vaccine administered in the boost phase for Esophageal Squamous Cell Carcinoma." ;
  rdfs:subClassOf obo:VO_0005496 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0011201 a rdfs:Class ;
  rdfs:label "GltX" ;
  rdfs:comment "Glutamyl tRNA synthetase (GtS) has been found to be among the Streptococcus pneumoniae cell wall-derived proteins that have age-dependent immunogenicity in children. Here, GtS was cloned, expressed, and purified and then was used to immunize 7-week-old BALB/c OlaHsd mice. Thirty-nine percent of rGtS-immunized mice survived a lethal bacterial challenge, whereas no control mice survived [PubMed: 17703427]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0004647 a rdfs:Class ;
  rdfs:label "cAdVax-based bivalent ebola virus vaccine (Sudan and Zaire species)" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0016180 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0003204 a rdfs:Class ;
  rdfs:label "Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML" ;
  rdfs:subClassOf obo:VO_0003199 .

obo:VO_0001877 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45H5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002331 .

obo:VO_0000076 a rdfs:Class ;
  rdfs:label "pBISIA DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003690 a rdfs:Class ;
  rdfs:label "Fluvirin 2017-2018 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003688 .

obo:VO_0015051 a rdfs:Class ;
  rdfs:label "M-M-R II Injectable Product" ;
  rdfs:subClassOf obo:VO_0000069 .

obo:VO_0007327 a rdfs:Class ;
  rdfs:label "BCG, Cell Wall Skeleton Vaccine" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000635 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0006056 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent booster preservative free 30 mcg/0.3 mL dose tris-sucrose formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0003991 a rdfs:Class ;
  rdfs:label "INFANRIX vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003958 .

obo:VO_0003400 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003399 .

obo:VO_0007288 a rdfs:Class ;
  rdfs:label "Autologous Dendritic Cell-based Immunotherapeutic AV0113 Vaccine" ;
  rdfs:comment "A therapeutic interleukin-12 (IL-12)-expressing dendritic cell (DC)-based vaccine composed of autologous monocyte-derived DCs loaded with autologous tumor cell lysate and exposed to the microbial cell wall component lipopolysaccharide (LPS), with potential immunomodulating and antineoplastic activities. The monocyte-derived immature DCs are loaded with autologous tumor cell lysates and are subsequently exposed to LPS and interferon-gamma (IFN-gamma). Upon administration of autologous DC-based immunotherapeutic AV0113, the mature DCs migrate into the lymph nodes, express the immune stimulatory cytokine interleukin-12 (IL-12) and activate the immune system by promoting the activation of natural killer (NK) cells and induce a cytotoxic T-lymphocyte (CTL)-mediated immune response against tumor cells, which may result in immune-mediated tumor cell death and inhibition of tumor cell proliferation. Exposure to LPS and IFN-gamma allows the maturation of DCs and optimizes the presentation of tumor-associated antigens (TAAs) by DCs to T-lymphocytes." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0003075 a rdfs:Class ;
  rdfs:label "Gardasil 9 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000534 , obo:VO_0000556 , obo:VO_0000667 , obo:VO_0000714 , obo:VO_0010446 .

obo:VO_0001083 a rdfs:Class ;
  rdfs:label "Giardia duodenalis vaccine" ;
  rdfs:comment "protozoan vaccine that is used to protect against Giardia intestinalis infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0007074 a rdfs:Class ;
  rdfs:label "PR1 Leukemia Peptide Vaccine" ;
  rdfs:comment "A cancer vaccine containing PR1, a 9 amino-acid human leukocyte antigen (HLA)-A2 restricted peptide derived from proteinase 3, with potential immunotherapeutic activity. Vaccination with PR1 leukemia peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing proteinase 3, resulting in tumor cell lysis. Often overexpressed in leukemic cells, proteinase 3 is a serine proteinase that activates progelatinase A and is involved in angiogenesis and metastasis." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0010044 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum RESA" ;
  rdfs:comment "A RESA protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0019201 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010432 .

obo:VO_0015269 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015268 , obo:VO_0015272 .

obo:OPMI_0000446 a rdfs:Class ;
  rdfs:label "immune biomarker"@en ;
  rdfs:comment "Biomarker that has a measurable quality or process profile(s), that can be used as an indicator of an underlying immune state or identity." ;
  rdfs:subClassOf obo:OPMI_0000445 .

obo:VO_0004279 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis mce-2 mutant vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0015696 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 20" ;
  rdfs:subClassOf obo:VO_0015567 , obo:VO_0015785 .

obo:VO_0002084 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.91)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0002199 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 1A88.R2)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0016819 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0016733 , obo:VO_0016768 .

obo:VO_0019212 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0020305 .

obo:VO_0015830 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Fendrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015625 .

obo:VO_0000979 a rdfs:Class ;
  rdfs:label "Bovilis IBR Marker vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000643 , obo:VO_0000987 .

obo:VO_0016538 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0006077 a rdfs:Class ;
  rdfs:label "tetanus toxoid unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010436 .

obo:VO_0020387 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0020359 , obo:VO_0020367 , obo:VO_0020389 .

obo:VO_0016798 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Covaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0016723 , obo:VO_0016740 , obo:VO_0016819 .

obo:VO_0010122 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii TgADF" ;
  rdfs:comment "A TgADF protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0015685 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 2" ;
  rdfs:subClassOf obo:VO_0015565 , obo:VO_0015778 .

obo:VO_0003677 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluvirin 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003675 , obo:VO_0003681 .

obo:VO_0000357 a rdfs:Class ;
  rdfs:label "pVIVO2 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003064 a rdfs:Class ;
  rdfs:label "obsolete RB51 induced protection against B.canis" .

obo:CL_0000000 a rdfs:Class ;
  rdfs:label "cell" ;
  rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:VO_0011026 a rdfs:Class ;
  rdfs:label "RAP-1" ;
  rdfs:comment "RAP-1 (21B4) is a candidate for inclusion in a B. bovis vaccine based on its ability to induce partial protection in vaccinates, defined as a significant reduction in parasitemia upon challenge [PubMed: 1441189]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010827 .

obo:VO_0004227 a rdfs:Class ;
  rdfs:label "cancer vaccine using E7 protein of human papillomavirus 16 and Algammulin" ;
  rdfs:comment "Gene name: E7" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005488 , obo:VO_0007657 .

obo:GO_0002250 a rdfs:Class ;
  rdfs:label "adaptive immune response" ;
  rdfs:comment "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." ;
  rdfs:subClassOf obo:GO_0006955 .

obo:VO_0018716 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.025 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010451 .

obo:VO_0001009 a rdfs:Class ;
  rdfs:label "plant-based Newcastle disease virus vaccine" ;
  rdfs:comment "The plant-based Newcastle disease virus vaccine is a Newcastle disease virus vaccine that is developed by Dow AgroSciences LLC. It uses technology discovered at Washington University. It is the first plant-made animal vaccine approved for sale in the United States." ;
  rdfs:subClassOf obo:VO_0001222 .

obo:VO_0016845 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 5 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016817 .

obo:VO_0001909 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002345 .

obo:VO_0017234 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella Pertussis Filamentous Haemagglutinin Antigen / diphtheria toxoid vaccine, inactivated / pertactin adsorbed / tetanus toxoid vaccine, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010444 .

obo:VO_0007250 a rdfs:Class ;
  rdfs:label "ALVAC(2)-NY-ESO-1 (M)/TRICOM vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a replication-defective recombinant canarypox virus [ALVAC(2)] encoding the cancer-testis antigen NY-ESO and the TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; also called TRICOM), with potential immunostimulatory and antineoplastic activities. Upon administration, ALVAC(2)/NY-ESO (M)/TRICOM vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against NY-ESO-expressing cancer cells, which may result in the inhibition of tumor cell proliferation. NY-ESO-1, a tumor associated antigen (TAA), is found in normal testis and on the surface of various tumor cells, including bladder, breast, hepatocellular, melanoma, and prostate tumor cells. TRICOM may enhance antigen presentation and activate cytotoxic T-cells. In addition, ALVAC(2) encodes the vaccinia virus (vv) E3L ad K3L genes, which may potentiate the translation of the NY-ESO and TRICOM genes." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:NCBITaxon_5820 a rdfs:Class ;
  rdfs:label "Plasmodium" ;
  rdfs:subClassOf obo:NCBITaxon_422676 .

obo:VO_0005356 a rdfs:Class ;
  rdfs:label "Adjuvax vaccine adjuvant" ;
  rdfs:comment "A carbohydrate vaccine adjuvant that is a glucan carbohydrate microcapsules with a beta(1-3)/beta(1-6) - linked glucan structure to allow targeting of antigens to macrophages or neutrophils through interactions with the beta-glucan receptor found uniquely on the surface of these cell types. Adjuvax- ligand complexes are formed by physically entrapping or crosslinking the ligand within the beta-glucan." ;
  rdfs:subClassOf obo:VO_0001359 .

obo:NCBITaxon_196 a rdfs:Class ;
  rdfs:label "Campylobacter fetus" ;
  rdfs:subClassOf obo:NCBITaxon_194 .

obo:VO_0005002 a rdfs:Class ;
  rdfs:label "pWRG DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pWRG.  This plasmid is a eukaryotic expression plasmid that contains the immediate early promoter and intron A of human cytomegalovirus." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015566 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015536 , obo:VO_0015595 .

obo:VO_0007136 a rdfs:Class ;
  rdfs:label "Pexastimogene-devacirepvec Vaccine" ;
  rdfs:comment "An oncolytic thymidine kinase (TK)-deleted vaccinia poxvirus expressing human GM-CSF (hGM-CSF) with antineoplastic activity. Upon intratumoral or intravenous administration, pexastimogene devacirepvec selectively infects and lyses tumor cells. While vaccinia displays a natural tumor cell tropism, deletion of the TK gene increases the tumor selectivity of vaccinia by limiting viral replication to cells expressing high levels of TK, such as certain cancer cells. hGM-CSF expression by this agent helps recruit antigen presenting cells (APCs), such as dendritic cells (DCs) and macrophages, to virally infected tumor cells, thereby initiating an antitumoral immune response." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005493 , obo:VO_0007657 .

obo:DOID_8622 a rdfs:Class ;
  rdfs:label "measles"@en ;
  rdfs:comment "A viral infectious disease that results_in infection located_in skin, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection has_symptom fever, has_symptom cough, has_symptom coryza, has_symptom conjunctivitis, and has_symptom maculopapular, erythematous rash."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0016624 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Twinrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015004 .

obo:VO_0002579 a rdfs:Class ;
  rdfs:label "crp from Edwardsiella ictaluri" ;
  rdfs:comment "A crp mutant is attenuated in zebrafish and catfish that were immunized intramuscularly and intracoelomically, respectively. Six weeks after immunization, both zebrafish and catfish were protected from challenge with wild type E. ictaluri" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001412 .

obo:VO_0018085 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0018084 , obo:VO_0018167 .

obo:VO_0001346 a rdfs:Class ;
  rdfs:label "formaldehyde vaccine preservative" ;
  rdfs:comment "a vaccine preservative that contains formaldehyde." ;
  rdfs:subClassOf obo:VO_0000851 .

obo:VO_0000130 a rdfs:Class ;
  rdfs:label "pcDNA I/Amp DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0011263 a rdfs:Class ;
  rdfs:label "Gag from HIV 1" ;
  rdfs:comment "HIV-1 DNA plasmids expressing Env, Gag and Tat, either alone or combined with the corresponding protein immunogens formulated in the MF59 adjuvant, resulted in protection against an experimental HIV-1 infection in C57Bl/6 mice [PubMed: 17707956]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010767 .

obo:VO_0010440 a rdfs:Class ;
  rdfs:label "licensed human Japanese encephalitis virus vaccine" ;
  rdfs:comment "Japanese encephalitis virus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000665 .

obo:VO_0019975 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML [Flulaval 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020338 .

obo:VO_0004396 a rdfs:Class ;
  rdfs:label "Brucella melitensis DNA vaccine p-Omp25" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000709 .

obo:PATO_0000719 a rdfs:Class ;
  rdfs:label "viable" ;
  rdfs:comment "A viability quality inhering in a bearer or a population by virtue of the bearer's ability to survive or the long term survival ability of a given population." ;
  rdfs:subClassOf obo:PATO_0000169 .

obo:VO_0020537 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0020533 , obo:VO_0020830 .

obo:VO_0000795 a rdfs:Class ;
  rdfs:label "mouse Ifng" ;
  rdfs:subClassOf obo:VO_0000792 .

obo:VO_0020328 a rdfs:Class ;
  rdfs:label "Flucelvax 2012-2013 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000980 , obo:VO_0010418 .

obo:VO_0007316 a rdfs:Class ;
  rdfs:label "Autologous TARP Peptide-Pulsed Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with autologous T cell receptor gamma-chain alternate reading frame protein (TARP) peptide with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, autologous TARP peptide-pulsed dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against TARP-expressing cancer cells, resulting in tumor cell lysis. The highly immunogenic nuclear protein TARP is commonly expressed in breast and prostate cancer cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0000919 a rdfs:Class ;
  rdfs:label "vaccine antigen" ;
  rdfs:comment "Vaccine component that is used as antigen to produce an immune responce protect against the specific pathogen or disease." ;
  rdfs:subClassOf obo:OBI_1110034 , obo:VO_0000179 .

obo:VO_0016671 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML [Covaxis]" ;
  rdfs:subClassOf obo:VO_0003429 .

obo:VO_0003523 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, Inactivated B-Brisbane-60-2008" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0001657 a rdfs:Class ;
  rdfs:label "Bursal Disease Standard & Variant, Live Virus Vaccine (USDA: 12B1.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:BFO_0000027 a rdfs:Class ;
  rdfs:label "object aggregate"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0015088 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015087 , obo:VO_0015246 .

obo:VO_0007658 a rdfs:Class ;
  rdfs:label "whole cell cancer vaccine" ;
  rdfs:comment "A cancer vaccine that uses whole cells to deliver cancer antigen(s)." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0019821 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0004247 a rdfs:Class ;
  rdfs:label "Group A streptococcal recombinant fusion peptide vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0002852 .

obo:VO_0019963 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluarix 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019943 .

obo:VO_0001640 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0019892 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Flulaval 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019889 , obo:VO_0020339 .

obo:VO_0007109 a rdfs:Class ;
  rdfs:label "Synchotrope TA2M DNA vaccine" ;
  rdfs:comment "A recombinant plasmid DNA vaccine encoding epitopes of tyrosinase with potential antineoplastic activity. Synchotrope TA2M vaccine contains a plasmid encoding 2 epitopes, amino acid sequences 207-216 and 1-17 of tyrosinase, a protein frequently expressed by melanoma cells. Vaccination with the TA2M plasmid DNA vaccine may induce the production of anti-tyrosinase antibodies as well as elicit a cytotoxic T-lymphocyte (CTL) response against tyrosinase-expressing tumor cells, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0004837 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0001526 a rdfs:Class ;
  rdfs:label "canine parainfluenza virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Canine parainfluenza virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0020049 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Fluvirin 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020355 .

obo:VO_0010118 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii ROP2" ;
  rdfs:comment "A ROP2 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0001372 a rdfs:Class ;
  rdfs:label "unimmunized" ;
  rdfs:comment "an organismal quality that indicates an organism (e.g., human) is not yet immunized against a disease." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:VO_0015154 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0007233 a rdfs:Class ;
  rdfs:label "allogeneic tumor cell vaccine" ;
  rdfs:comment "A vaccine composed of tumor cells isolated from the tumor of one patient, killed and processed, and administered to another patient to stimulate cytotoxic immune responses to a similar tumor cell type. The cells found in this type of whole-cell vaccine express many cell-surface tumor-associated antigens. This vaccine is frequently administered with an adjuvant immunostimulant." ;
  rdfs:subClassOf obo:VO_0005430 , obo:VO_0005484 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0003851 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0000104 .

obo:VO_0001688 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1641.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0010026 a rdfs:Class ;
  rdfs:label "Leishmania  major LIPO-A" ;
  rdfs:comment "A LIPO-A protein that is part of Leishmania  major" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:PATO_0002147 a rdfs:Class ;
  rdfs:label "reduced virulence" ;
  rdfs:comment "A virulence that is relatively low." ;
  rdfs:subClassOf obo:PATO_0002146 , obo:PATO_0002303 .

obo:VO_0011071 a rdfs:Class ;
  rdfs:label "IglB" ;
  rdfs:comment "Intranasal vaccination with KKF235 (F. tularensis subsp. novicida mutant (DeltaiglB) ) protected mice from subsequent homotypic challenge with U112 as well as heterotypic challenge with F. tularensis subsp. holarctica (LVS).  Most significantly, oral immunization with KKF235 protected mice from a highly lethal subsp. tularensis (SCHU S4) pulmonary challenge [PubMed: 20016043]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:VO_0010880 a rdfs:Class ;
  rdfs:label "GatB" ;
  rdfs:comment """Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #3, gatB) was found to be protective.  Three of the clones (CP #1) elicited protection that was statistically higher than the unvaccinated control, which has high variance [PubMed: 15811648].

Note:  Part of CP #3 also belongs to gatA""" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:VO_0020067 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluvirin 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020471 .

obo:VO_0015115 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015111 .

obo:VO_0000575 a rdfs:Class ;
  rdfs:label "vaccine candidate" ;
  rdfs:comment "vaccine candidate is a processed material that is designed to prevent or ameliorate a disorder in a target organism by modulating adaptive immune responses in that organism by administrating the vaccine." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:VO_0020424 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typherix] Box of 1" ;
  rdfs:subClassOf obo:VO_0020393 , obo:VO_0020430 .

obo:VO_0017372 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Boostrix]" ;
  rdfs:subClassOf obo:VO_0018786 .

obo:VO_0002232 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.26)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002487 , obo:VO_0007748 .

obo:VO_0000945 a rdfs:Class ;
  rdfs:label "Measles-Rubella vaccine" ;
  rdfs:comment "A Measles virus vaccine that is also used against Rubella virus infection." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010441 , obo:VO_0010450 .

obo:VO_0019974 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML [Flucelvax 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020328 .

obo:VO_0007171 a rdfs:Class ;
  rdfs:label "Recombinant Adenovirus 5 Encoding Tumor Necrosis Factor-related Apoptosis-Inducing Ligand Vaccine" ;
  rdfs:comment "An adenovirus type 5 (Ad5) encoding human tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), with potential apoptosis-inducing and antineoplastic activities. Upon administration of recombinant Ad5 encoding TRAIL, the adenovirus selectively infects tumor cells and expresses TRAIL. The virally expressed TRAIL binds to and activates its receptors TRAIL receptor-1 (TRAIL-R1, death receptor 4, DR4) and TRAIL receptor-2 (TRAIL-R2, death receptor 5, DR5), which subsequently activate caspases and induce apoptosis in TRAIL-R1/R2-expressing tumor cells. The pro-apoptotic cell surface receptors TRAIL-R1 and -R2, members of the TNF receptor family, are overexpressed by a variety of cancer cell types." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0015139 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015306 .

obo:VO_0010455 a rdfs:Class ;
  rdfs:label "licensed human vibrio cholerae vaccine" ;
  rdfs:comment "Vibrio cholerae vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000763 .

obo:VO_0015674 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015491 .

obo:VO_0020166 a rdfs:Class ;
  rdfs:label "pertussis vaccine 8 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010435 .

obo:VO_0017828 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.3 MG/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017854 .

obo:VO_0016782 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Covaxis] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016723 .

obo:DOID_8469 a rdfs:Class ;
  rdfs:label "influenza"@en ;
  rdfs:comment "A viral infectious disease that results in infection, located in respiratory tract, has_material_basis_in Influenzavirus A (Alphainfluenzavirus), has_material_basis_in Influenzavirus B (Betainfluenzavirus), or has_material_basis_in Influenzavirus C (Gammainfluenzavirus), which are transmitted_by droplet spread of oronasal secretions during coughing, sneezing, or talking from an infected person. It is a highly contagious disease that affects birds and mammals and has_symptom chills, has_symptom fever, has_symptom sore throat, has_symptom runny nose, has_symptom muscle pains, has_symptom severe headache, has_symptom cough, and has_symptom weakness."@en ;
  rdfs:subClassOf obo:DOID_1579 , obo:DOID_934 .

obo:IAO_0000100 a rdfs:Class ;
  rdfs:label "data set"@en ;
  rdfs:comment "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:VO_0018002 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution Box of 5 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018001 .

obo:VO_0015588 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015499 , obo:VO_0015549 .

obo:VO_0010133 a rdfs:Class ;
  rdfs:label "influenza, seasonal vaccine, quadrivalent, adjuvanted, 0.5mL dose, preservative free" ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000647 .

obo:VO_0010848 a rdfs:Class ;
  rdfs:label "Vibrio cholerae protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0018915 a rdfs:Class ;
  rdfs:label "influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.0857 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0018929 a rdfs:Class ;
  rdfs:label "yellow fever virus strain 17D-204 live antigen" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0011104 a rdfs:Class ;
  rdfs:label "US8" ;
  rdfs:comment "Protection against a lethal intraperitoneal challenge of HSV-1 (5 x 10(4) pfu) with gC or gE (US8) plasmid vaccination could be demonstrated if the inoculating dose of DNA was 250 microg. All mice immunized with vaccinia recombinants expressing either gC or gE survived HSV-1 challenge [PubMed: 9728527]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010834 .

obo:VO_0020692 a rdfs:Class ;
  rdfs:label "Aconitum napellus extract / ferrous cation / Gelsemium Sempervirens Preparation / Gentiana lutea root extract / Influenza A virus / Lactate / Luffa operculata whole extract / VERATRUM ALBUM Preparation Oral Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0003571 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 6B vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003250 .

obo:VO_0003411 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003409 .

obo:VO_0004561 a rdfs:Class ;
  rdfs:label "Helicobacter pylori DNA vaccine pcDNA3.2-hspB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012181 .

obo:VO_0019132 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010431 .

obo:VO_0019919 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Injectable Suspension [Fluvirin 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019916 , obo:VO_0020473 .

obo:VO_0007420 a rdfs:Class ;
  rdfs:label "MUC-2-KLH vaccine" ;
  rdfs:comment "A peptide vaccine containing human mucin 2 (MUC2) protein conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. MUC2, a secretory or gel forming glycoprotein expressed predominantly in goblet cells of the gastrointestinal and respiratory tracts, is overexpressed as an aberrant or deglycosylated form in various tumors such as gastric carcinomas and some hormone-refractory prostate cancers. MUC2 protein is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition. Vaccination with MUC2-KLH may result in the production of antibodies as well as elicit a cytotoxic T- lymphocyte (CTL) response against tumor cells expressing MUC2" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0002182 a rdfs:Class ;
  rdfs:label "Marek's Disease-Newcastle Disease Serotypes 2 & 3, Live Virus & Live Marek's Disease Vector Vaccine (USDA: 17H1.R1)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002447 , obo:VO_0007748 .

obo:VO_0005166 a rdfs:Class ;
  rdfs:label "BBIBP-CorV vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated whole virus vaccine that produced in Vero cells that is developed by the Beijing Institute of Biological Products." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0010415 a rdfs:Class ;
  rdfs:label "licensed human influenza virus vaccine" ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0003143 , obo:VO_0003495 .

obo:VO_0007406 a rdfs:Class ;
  rdfs:label "inalimarev vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a recombinant vaccinia viral vector encoding the carcinoembryonic antigen (CEA), MUC-1 (mucin-1), a transmembrane glycoprotein secreted by glandular tissues, and TRICOM, comprised of the three co-stimulatory molecule transgenes B7-1, ICAM-1 and LFA-3. Upon administration, inalimarev may enhance CEA and MUC-1 presentation to antigen presenting cells (APC) and may activate a cytotoxic T lymphocyte (CTL) response against CEA- and MUC-1-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0015040 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine 0.08 MG/ML" ;
  rdfs:subClassOf obo:VO_0003301 .

obo:VO_0019451 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0002925 a rdfs:Class ;
  rdfs:label "Brucella ovis vaccine" ;
  rdfs:comment "a Brucella vaccine against infection wtih B. ovis" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000025 .

obo:VO_0007046 a rdfs:Class ;
  rdfs:label "synthetic peptides E-PRA and E-PSM vaccine" ;
  rdfs:comment "A cancer vaccine consisting of E-PRA and E-PSM, two synthetic peptide analogs of PRAME (PReferential Antigen MElanoma) and PSMA (Prostate Specific Membrane Antigen), with potential immunostimulating activity. Upon direct administration into lymph nodes, synthetic peptides E-PRA and E-PSM vaccine may sitmulate a cytotoxic T-lymphocyte (CTL) response against PRAME- and PSMA-expressing tumor cells. PRAME and PSMA are tumor-associated antigens upregulated and expressed on the cell surfaces of certain tumor cell types." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0017370 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxin Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0003616 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 .

obo:NCBITaxon_3052707 a rdfs:Class ;
  rdfs:label "Protoparvovirus carnivoran1" ;
  rdfs:subClassOf obo:NCBITaxon_1506574 .

obo:IAO_8000002 a rdfs:Class ;
  rdfs:label "editors ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:VO_0017077 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0017074 , obo:VO_0017118 , obo:VO_0017558 .

obo:VO_0002909 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium ruvB mutant vaccine" ;
  rdfs:comment "A ruvB mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0001203 a rdfs:Class ;
  rdfs:label "vaccination-challenge interval in days" ;
  rdfs:comment "A measurement datum that represents a length of days as the interval between a vaccination and a challenge in a specific vaccine protection study. " ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0000397 a rdfs:Class ;
  rdfs:label "neutralizing antibody role" ;
  rdfs:subClassOf obo:VO_0000148 .

obo:VO_0017316 a rdfs:Class ;
  rdfs:label "Diphtheria Antitoxin / diphtheria toxoid vaccine, inactivated / influenza B virus antigen, Hong Kong 330-2001 / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0010415 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0017668 .

obo:VO_0003464 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010438 .

obo:VO_0005277 a rdfs:Class ;
  rdfs:label "mRNA-1273.211 vaccine" ;
  rdfs:comment "A multivalent SARS-CoV-2 mRNA booster vaccine which combines mRNA-1273, Moderna's authorized vaccine against ancestral strains, and mRNA-1273.351 in a single vaccine at the 50 ug dose level and lower." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0002034 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002326 , obo:VO_0007748 .

obo:VO_0001402 a rdfs:Class ;
  rdfs:label "Bacillus anthracis gene" ;
  rdfs:comment "A bacterial gene that is from Bacillus anthracis." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0000924 a rdfs:Class ;
  rdfs:label "glutaraldehyde vaccine additive" ;
  rdfs:subClassOf obo:VO_0000851 .

obo:VO_0005226 a rdfs:Class ;
  rdfs:label "Razi Cov Pars vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by the Razi Vaccine and Serum Research Institute with a Spike protein antigen" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0016719 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003429 , obo:VO_0016706 .

obo:OPL_0000351 a rdfs:Class ;
  rdfs:label "Plasmodium berghei sporazoite stage" ;
  rdfs:comment "A sporozoite stage in the Plasmodium berghei life cycle." ;
  rdfs:subClassOf obo:OPL_0000152 , obo:OPL_0000300 , obo:OPL_0000375 .

obo:DOID_3856 a rdfs:Class ;
  rdfs:label "male reproductive organ cancer"@en ;
  rdfs:comment "A reproductive organ cancer that is manifested in the male genital system. This includes organs such as the penis and scrotum."@en ;
  rdfs:subClassOf obo:DOID_193 , obo:DOID_48 .

obo:NCBITaxon_10114 a rdfs:Class ;
  rdfs:label "Rattus" ;
  rdfs:subClassOf obo:NCBITaxon_39107 .

obo:VO_0000100 a rdfs:Class ;
  rdfs:label "vaccine-induced T-helper 1 type immune response" ;
  rdfs:comment "T helper type 1 (Th1) lymphocytes secrete secrete interleukin (IL)-2, interferon-γ, and lymphotoxin-α and stimulate type 1 immunity, which is characterized by intense phagocytic activity. https://academic.oup.com/cid/article/32/1/76/311106" ;
  rdfs:subClassOf obo:VO_0000106 .

obo:VO_0019599 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Nasal Spray [FluMist Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019592 , obo:VO_0020353 .

obo:VO_0001335 a rdfs:Class ;
  rdfs:label "albumin-heparin microparticles vaccine adjuvant" ;
  rdfs:comment "A particulate antigen delivery system vaccine adjuvant  that is albumin-heparin microparticles vaccine adjuvant that is prepared from albumin and heparin stabilized by cross-linking reaction with EDC." ;
  rdfs:subClassOf obo:VO_0001356 .

obo:VO_0017223 a rdfs:Class ;
  rdfs:label "7.5 ML tetanus toxoid vaccine, inactivated 5.33 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017583 .

obo:IAO_8000017 a rdfs:Class ;
  rdfs:label "ontology module subsetted by expressivity"@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:VO_0011111 a rdfs:Class ;
  rdfs:label "NP from Influenza A virus H3N2" ;
  rdfs:comment "BALB/c mice were immunized intranasally with an adjuvant (cholera toxin B subunit containing 0.2% of the whole toxin)-combined with A or B virus recombinant NP. The NP-immune mice, when challenged intranasally with a sublethal dose of the virus 3 wk after immunization, had accelerated virus clearance from the nasal site in both an influenza type-specific and a nonspecific manner, as shown by the protection from high morbidity from the second day after challenge [PubMed: 8621928]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0016091 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015992 .

obo:VO_0020987 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, strain A / Victoria / 361/2011 H3N2 - Derived Strain Used Ivr-165 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0020982 .

obo:VO_0018874 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0000334 a rdfs:Class ;
  rdfs:label "pVR1012 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007149 a rdfs:Class ;
  rdfs:label "PSA Prostate Cancer Vaccine" ;
  rdfs:comment "A peptide vaccine containing the prostate specific antigen (PSA) with potential antineoplastic activity. PSA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed in prostate cancer cells and is used as a tumor marker for both diagnosis and treatment evaluation. Vaccination with PSA peptide vaccine may produce anti-PSA antibodies as well as elicit a cytotoxic T-cell (CTL) response against prostate cancer cells expressing this antigen, thereby decreasing tumor cell growth." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0017474 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017471 .

obo:VO_0007192 a rdfs:Class ;
  rdfs:label "851B Gel vaccine" ;
  rdfs:comment "A topical gel containing a peptide derived from the human papillomavirus (HPV). Application of 851B gel may stimulate the host immune system to trigger a cytotoxic T-lymphocyte response to cells that express HPV." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0010271 a rdfs:Class ;
  rdfs:label "challenge admistration route datum" ;
  rdfs:comment "A measurment datum that records the route of a pathogen challenge occurs in." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0002008 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus-Mannheimia Haemolytica-Pasteurella Multocida Modified Live Virus, Avirulent Live Culture Vaccine (USDA: 11A8.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002371 .

obo:VO_0016851 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Diphtherie-Adsorbat-Impfstoff Behring] Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0016799 .

obo:VO_0017635 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017632 , obo:VO_0017639 .

obo:VO_0019851 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010423 .

obo:VO_0018288 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003858 , obo:VO_0018274 .

obo:VO_0018396 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe [Prevnar]" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0015732 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015803 .

obo:VO_0010720 a rdfs:Class ;
  rdfs:label "Infanrix/Hib vaccine" ;
  rdfs:subClassOf obo:VO_0000714 , obo:VO_0003168 .

obo:VO_0019881 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Fluzone Quadrivalent 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003611 .

obo:VO_0019574 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003638 , obo:VO_0019544 .

obo:VO_0016030 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 3" ;
  rdfs:subClassOf obo:VO_0015667 , obo:VO_0015781 .

obo:VO_0001292 a rdfs:Class ;
  rdfs:label "gamma Inulin vaccine adjuvant" ;
  rdfs:comment "A carbohydrate adjuvant that is a highly specific activator of the alternative pathway of complement in vitro and in vivo, and is composed of linear (unbranched) b-D-(2-1) polyfructofuranosyl-a-D-glucose." ;
  rdfs:subClassOf obo:VO_0001359 .

obo:VO_0020771 a rdfs:Class ;
  rdfs:label "BCG, live, Tice strain 12.5 MG Injection [OncoTICE] by Organon" ;
  rdfs:subClassOf obo:VO_0020769 .

obo:VO_0001476 a rdfs:Class ;
  rdfs:label "sheep vaccine" ;
  rdfs:comment "Vaccine that used for immunizing sheep." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001218 .

obo:VO_0007290 a rdfs:Class ;
  rdfs:label "autologous dinitrophenyl vaccine" ;
  rdfs:comment "A vaccine consisting of autologous cancer cells modified with the hapten, Dinitrophenyl. The treatment program consists of multiple intradermal injections of irradiated DNP-modified autologous tumor cells mixed with bacillus Calmette-Guerin." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0001927 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002353 .

obo:OPL_0000285 a rdfs:Class ;
  rdfs:label "Plasmodium zygote" ;
  rdfs:comment "A Plasmodium that is formed after fertilization of the macrogamete by a microgamete in the midgut of the mosquito vector. This round form is the only diploid stage in the Plasmodium life cycle." ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0005282 a rdfs:Class ;
  rdfs:label "UM-1098 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002041 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotypes 1 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 1281.R1)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0010974 a rdfs:Class ;
  rdfs:label "GNA1946" ;
  rdfs:comment "Protective antigen [PubMed: 10710308]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0015099 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Havpur]" ;
  rdfs:subClassOf obo:VO_0015094 , obo:VO_0015256 .

obo:VO_0019959 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Fluzone 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019952 , obo:VO_0020482 .

obo:VO_0002568 a rdfs:Class ;
  rdfs:label "pgk from B. abortus" ;
  rdfs:comment "A pgk mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000793 .

obo:VO_0015629 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015562 , obo:VO_0015665 .

obo:VO_0017936 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group B vaccine 0.3 MG/ML Injectable Suspension [Bexsero]" ;
  rdfs:subClassOf obo:VO_0017902 .

obo:VO_0015569 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0015491 , obo:VO_0015547 .

obo:VO_0004059 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis HBHA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0019601 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0001378 a rdfs:Class ;
  rdfs:label "vaccinated with a licensed vaccine" ;
  rdfs:comment "a vaccinated quality that indicates an organism is vaccinated with a licensed vaccine." ;
  rdfs:subClassOf obo:VO_0001376 .

obo:VO_0001978 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:DOID_1192 a rdfs:Class ;
  rdfs:label "peripheral nervous system neoplasm"@en ;
  rdfs:comment "A nervous system cancer that is located in the peripheral nervous system."@en ;
  rdfs:subClassOf obo:DOID_3093 , obo:DOID_574 .

obo:NCBITaxon_2697049 a rdfs:Class ;
  rdfs:label "Severe acute respiratory syndrome coronavirus 2" ;
  rdfs:subClassOf obo:NCBITaxon_694009 .

obo:VO_0000480 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae LOS-TT conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000471 .

obo:NCBITaxon_28450 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei" ;
  rdfs:subClassOf obo:NCBITaxon_80840 .

obo:VO_0000200 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0007030 a rdfs:Class ;
  rdfs:label "p53 peptide vaccine" ;
  rdfs:comment "A peptide-based cancer vaccine composed of amino acids 264 to 272 of the wild-type protein encoded by the P53 gene. p53 peptide vaccine may elicit an HLA-A2.1-restricted cytotoxic T lymphocyte immune response against tumor cells that overexpress p53 protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0017636 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0017631 .

obo:NCBITaxon_10535 a rdfs:Class ;
  rdfs:label "unidentified adenovirus" ;
  rdfs:subClassOf obo:NCBITaxon_10509 .

obo:NCBITaxon_10320 a rdfs:Class ;
  rdfs:label "bovine alphaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_10319 .

obo:NCBITaxon_28115 a rdfs:Class ;
  rdfs:label "Porphyromonas macacae" ;
  rdfs:subClassOf obo:NCBITaxon_836 .

obo:VO_0001823 a rdfs:Class ;
  rdfs:label "Escherichia coli live culture vaccine (USDA: 1551.R0)" ;
  rdfs:subClassOf obo:VO_0000125 , obo:VO_0000455 , obo:VO_0000619 , obo:VO_0007748 .

obo:VO_0017175 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017174 .

obo:VO_0001707 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.18)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0007389 a rdfs:Class ;
  rdfs:label "IDH1R132H Mutation-targeting IDH1 Peptide Vaccine" ;
  rdfs:comment "Gene name: IDH1" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:NCBITaxon_5865 a rdfs:Class ;
  rdfs:label "Babesia bovis" ;
  rdfs:subClassOf obo:NCBITaxon_5864 .

obo:VO_0003624 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine 0.1 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003623 .

obo:VO_0007160 a rdfs:Class ;
  rdfs:label "Recombinant Fowlpox-Prostate Specific Antigen Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant fowlpox virus encoding human prostate-specific antigen (PSA). Administration of this agent may stimulate a cytotoxic T cell response against PSA-expressing tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0017411 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017358 .

obo:VO_0018646 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine / L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine / L1 protein, Human papillomavirus type 6 Vaccine Prefilled Syringe [Silgard]" ;
  rdfs:subClassOf obo:VO_0018802 .

obo:VO_0004080 a rdfs:Class ;
  rdfs:label "V-LSG vaccine" ;
  rdfs:subClassOf obo:VO_0012177 .

obo:VO_0003869 a rdfs:Class ;
  rdfs:label "HIBERIX vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003867 , obo:VO_0020832 .

obo:VO_0003925 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Fluad 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003912 .

obo:VO_0000999 a rdfs:Class ;
  rdfs:label "pVCL1012 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pVCL1012. The promoter is HCMV and the manufacturer is Vical Inc." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015996 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0015659 , obo:VO_0015782 .

obo:VO_0010429 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2023" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0000252 a rdfs:Class ;
  rdfs:label "pDRVISV1.0 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019795 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0018686 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML [Rotarix]" ;
  rdfs:subClassOf obo:VO_0010738 , obo:VO_0018685 .

obo:VO_0003829 a rdfs:Class ;
  rdfs:label "Havrix adult vaccine 1440 UNT in 1 ML Injection" ;
  rdfs:subClassOf obo:VO_0003830 .

obo:VO_0016208 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0004424 a rdfs:Class ;
  rdfs:label "VEE virus recombinant vector vaccine RAd/VEEV#3 encoding TC-83" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0001499 .

obo:VO_0004996 a rdfs:Class ;
  rdfs:label "AdCLD-CoV19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 replication-defective human adenovirus type 5/35 vector based vaccine expressing the S protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:VO_0010469 a rdfs:Class ;
  rdfs:label "cocorrelate of immune protection" ;
  rdfs:subClassOf obo:VO_0010468 .

obo:VO_0017463 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 0.088 MG/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0012180 a rdfs:Class ;
  rdfs:label "canine parvovirus vaccine" ;
  rdfs:comment "A vaccine that protects against Canine parvovirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0016939 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 25 LFU/ML / Pertussis Vaccine 8 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution [Tri-Immunol Im]" ;
  rdfs:subClassOf obo:VO_0016938 , obo:VO_0017402 .

obo:VO_0020778 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 CELLS Injectable Suspension [OncoTICE] Box of 1 by MSD" ;
  rdfs:subClassOf obo:VO_0020777 .

obo:VO_0001220 a rdfs:Class ;
  rdfs:label "live attenuated viral vaccine" ;
  rdfs:comment "a viral vaccine that is live attenuated" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000609 .

obo:VO_0000083 a rdfs:Class ;
  rdfs:label "PedvaxHIB vaccine" ;
  rdfs:comment """PedvaxHIB is a highly purified capsular polysaccharide (polyribosylribitol phosphate or PRP) of Haemophilus
influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an outer membrane protein complex (OMPC) of the B11 strain of Neisseria meningitidis serogroup B.""" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000662 , obo:VO_0010437 .

obo:VO_0016577 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000745 , obo:VO_0001214 .

obo:VO_0015548 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [H B Vax]" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0000511 a rdfs:Class ;
  rdfs:label "ETEC vaccine ACAM2007" ;
  rdfs:comment "ACAM2007 is a vaccine candidate expressing CFA/II." ;
  rdfs:subClassOf obo:VO_0000619 .

obo:VO_0003764 a rdfs:Class ;
  rdfs:label "FluLaval Quadrivalent 2015-2016 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003763 .

obo:VO_0001774 a rdfs:Class ;
  rdfs:label "equine influenza killed virus vaccine (USDA: 1505.28)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0001176 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0000718 a rdfs:Class ;
  rdfs:label "live attenuated vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a live attenuated vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:DOID_4896 a rdfs:Class ;
  rdfs:label "bile duct adenocarcinoma"@en ;
  rdfs:comment "A bile duct carcinoma that derives_from epithelial cells of glandular origin."@en ;
  rdfs:subClassOf obo:DOID_299 , obo:DOID_4897 .

obo:VO_0017922 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injection [Menveo]" ;
  rdfs:subClassOf obo:VO_0017820 .

obo:VO_0005160 a rdfs:Class ;
  rdfs:label "WIBP-CorV vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated whole virus vaccine that is developed by the Wuhan Institute of Biological Products." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0007502 a rdfs:Class ;
  rdfs:label "MART-1 Adenovirus vaccine" ;
  rdfs:comment "A vaccine consisting of recombinant adenovirus vector encoding MART-1 (melanoma antigen recognized by T-cells 1), an immunogenic protein of unknown function that is expressed by certain types of melanoma. Vaccination with MART-1 adenovirus vaccine may stimulate the host immune system to direct cytotoxic T lymphocytes (CTL) against MART-1 positive melanoma cells, resulting in an antitumor effect." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0000838 a rdfs:Class ;
  rdfs:label "Ovilis Enzovax vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000503 , obo:VO_0001085 .

obo:VO_0011418 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum Pfen protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000534 .

obo:VO_0000043 a rdfs:Class ;
  rdfs:label "FluLaval" ;
  rdfs:comment "Product Name: Influenza Virus Vaccine, Trivalent, Types A and B" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0010415 .

obo:NCBITaxon_10892 a rdfs:Class ;
  rdfs:label "Orbivirus" ;
  rdfs:subClassOf obo:NCBITaxon_2946186 .

obo:VO_0003305 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 33 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003299 , obo:VO_0010446 .

obo:VO_0002293 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4975.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002462 , obo:VO_0007748 .

obo:VO_0000565 a rdfs:Class ;
  rdfs:label "rBCG-Ag85A[Tokyo] vaccine" ;
  rdfs:subClassOf obo:VO_0003130 .

obo:VO_0010927 a rdfs:Class ;
  rdfs:label "ORF" ;
  rdfs:comment "This  gene was originally isolated from a lambda gt11 expression library probed with sera from Brucella-infected sheep. Sequence analysis of the cloned gene revealed the presence of an open reading frame of 158 amino acids encoding a protein of 17.3 kDa [PubMed: 7664168 ]. It was later identified as a cytoplasmic protein lumazine synthase [PubMed: 10482294 ]. This gene can be used for diagnosis [PubMed: 7664168 ] [PubMed: 10482294 ] and vaccine development [PubMed: 11953389 ]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0016099 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0015993 .

obo:VO_0020597 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Viroflu] Box of 10 by Crucell" ;
  rdfs:subClassOf obo:VO_0020596 .

obo:VO_0018184 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection" ;
  rdfs:subClassOf obo:VO_0000737 .

obo:NCBITaxon_11153 a rdfs:Class ;
  rdfs:label "Canine coronavirus" ;
  rdfs:subClassOf obo:NCBITaxon_693997 .

obo:VO_0018277 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabivac]" ;
  rdfs:subClassOf obo:VO_0018257 , obo:VO_0018262 , obo:VO_0018284 .

obo:VO_0005042 a rdfs:Class ;
  rdfs:label "Auxo-GTU DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label Auxo-GTU." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0018885 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.0857 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0010338 a rdfs:Class ;
  rdfs:label "AREXVY vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000753 .

obo:VO_0004717 a rdfs:Class ;
  rdfs:label "rCMV- EBOV vaccine" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0007227 a rdfs:Class ;
  rdfs:label "Allogeneic Large Multivalent Immunogen Breast Cancer Vaccine" ;
  rdfs:comment "A cancer vaccine, containing human-specific large multivalent immunogens (LMIs) isolated from the membrane fraction of cells from a breast cancer cell line, with potential immunostimulatory and antineoplastic activities. Upon administration, allogeneic large multivalent immunogen breast cancer vaccine may stimulate a cytotoxic T lymphocyte (CTL) immune response against tumor cells that express the breast cancer cell-specific LMIs." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0002511 a rdfs:Class ;
  rdfs:label "human metapneumovirus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection of human metapneumovirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0010479 a rdfs:Class ;
  rdfs:label "licensed human Lyme disease vaccine" ;
  rdfs:comment "Borrelia burgdorferi vaccine that is licensed for use in humans preventing Lyme disease." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000764 .

obo:VO_0020259 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 0.5 ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0002209 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002412 , obo:VO_0007748 .

obo:VO_0020344 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2020-2021 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 , obo:VO_0010424 .

obo:VO_0005266 a rdfs:Class ;
  rdfs:label "authorized inactivated COVID-19 vaccine" ;
  rdfs:subClassOf obo:VO_0005201 , obo:VO_0005264 .

obo:VO_0019361 a rdfs:Class ;
  rdfs:label "1 ML hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML / typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.025 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019499 .

obo:VO_0016906 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection Box of 5" ;
  rdfs:subClassOf obo:VO_0016903 , obo:VO_0017286 .

obo:VO_0019295 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Flucelvax 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020329 .

obo:VO_0017891 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017812 .

obo:VO_0015020 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injection [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0015019 .

obo:VO_0000504 a rdfs:Class ;
  rdfs:label "whole organism vaccine role" ;
  rdfs:comment "a vaccine role that indicates the vaccine being a whole organism vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0015905 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10" ;
  rdfs:subClassOf obo:VO_0003267 .

obo:VO_0004067 a rdfs:Class ;
  rdfs:label "Leishmania donovani HASPB1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001142 .

obo:NCBITaxon_12059 a rdfs:Class ;
  rdfs:label "Enterovirus" ;
  rdfs:subClassOf obo:NCBITaxon_12058 .

obo:VO_0018356 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG" ;
  rdfs:subClassOf obo:VO_0003340 .

obo:VO_0005161 a rdfs:Class ;
  rdfs:label "ARCoV vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine made of lipid nanoparticle-encapsulated mRNA (mRNA-LNP) encoding the receptor binding domain (RBD) of SARS-CoV-2 manufactured by Academy of Military Science (AMS), Walvax Biotechnology, and Suzhou Abogen Biosciences." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0005293 a rdfs:Class ;
  rdfs:label "Em vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0020410 a rdfs:Class ;
  rdfs:label "0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0020392 .

obo:VO_0002272 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4875.24)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000539 , obo:VO_0000640 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0019480 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.03 MG/ML / Neisseria meningitidis 0.5 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0019468 .

obo:VO_0000038 a rdfs:Class ;
  rdfs:label "vaccine persistence assay" ;
  rdfs:comment "An assay that measures the persistent survival of live vaccine in a host in vivo." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0007035 a rdfs:Class ;
  rdfs:label "RAS peptide cancer vaccine" ;
  rdfs:comment "A cancer vaccine containing a RAS oncogene-encoded peptide with potential antineoplastic activity. RAS peptide cancer vaccine may stimulate a RAS peptide-specific antitumoral T-cell cytotoxic immune response, resulting in an inhibition of tumor cell proliferation and tumor cell death." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005430 , obo:VO_0005486 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0004798 a rdfs:Class ;
  rdfs:label "NILV-Py CSP vaccine" ;
  rdfs:subClassOf obo:VO_0002514 .

obo:VO_0020443 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 50" ;
  rdfs:subClassOf obo:VO_0020408 , obo:VO_0020419 .

obo:VO_0015124 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML Injectable Solution [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015123 , obo:VO_0015125 , obo:VO_0015288 .

obo:VO_0018630 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 1 UNT Injectable Suspension [Je-Vax] by The Res.Found.For Microb.Dis.Osaka University" ;
  rdfs:subClassOf obo:VO_0018629 .

obo:VO_0002714 a rdfs:Class ;
  rdfs:label "7a from Feline infectious peritonitis virus" ;
  rdfs:comment "A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001434 .

obo:VO_0015721 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites] Box of 1" ;
  rdfs:subClassOf obo:VO_0015573 , obo:VO_0015794 .

obo:VO_0020580 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC] Box of 10" ;
  rdfs:subClassOf obo:VO_0020579 , obo:VO_0020603 , obo:VO_0020873 .

obo:VO_0012176 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum vaccine" ;
  rdfs:comment "A Chlamydia vaccine that protects against Chlamydia muridarum." ;
  rdfs:subClassOf obo:VO_0000573 .

obo:VO_0011082 a rdfs:Class ;
  rdfs:label "OmpP5" ;
  rdfs:comment "In a chinchilla model of otitis media, initial screening of P5-fimbrin, delivered singly or in combination with either Freund's adjuvant or alum, indicated that augmented bacterial clearance from the nasopharynx, the middle ears, or both anatomical sites could be induced by parenteral immunization with P5-fimbrin combined with lipoprotein D, lipoprotein D alone, or the synthetic chimeric peptide LB1 (derived from P5-fimbrin), respectively [PubMed: 10338477]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:VO_0007671 a rdfs:Class ;
  rdfs:label "HLA neoantigen vaccine" ;
  rdfs:comment "A cancer vaccine for vaccination with neoantigens that can both expand pre-existing neoantigen-specific T-cell populations and induce a broader repertoire of new T-cell specificities in cancer patients, tipping the intra-tumoural balance in favour of enhanced tumour control. The vaccine targets up to 20 predicted personal tumour neoantigens. The vaccine induced CD4+ and CD8+ T cells responses. These T cells discriminated mutated from wild-type antigens, and in some cases directly recognized autologous tumour." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0000292 a rdfs:Class ;
  rdfs:label "host response to vaccine vaccine vector" ;
  rdfs:comment "a process that specifies host response to a vaccine vector." ;
  rdfs:subClassOf obo:VO_0000290 .

obo:NCBITaxon_5825 a rdfs:Class ;
  rdfs:label "Plasmodium chabaudi" ;
  rdfs:subClassOf obo:NCBITaxon_418101 .

obo:CHEBI_33130 a rdfs:Class ;
  rdfs:label "aluminium hydroxide" ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0000741 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae serotype b" ;
  rdfs:subClassOf obo:NCBITaxon_727 .

obo:VO_0016473 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0020871 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Influsplit] Box of 20" ;
  rdfs:subClassOf obo:VO_0020869 , obo:VO_0020885 .

obo:VO_0007470 a rdfs:Class ;
  rdfs:label "KLH-Lymphoma Ig Vaccine" ;
  rdfs:comment "A chimeric lymphoma vaccine generated by combining the recipient's Ig idiotype (Id) protein with keyhole limpet hemocyanin (KLH), an immune stimulant, with potential antineoplastic activity. Vaccination with KLH-Lymphoma Ig Vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against lymphoma cells, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0007169 a rdfs:Class ;
  rdfs:label "Telomerase Peptide Vaccine GV1001" ;
  rdfs:comment "A synthetic peptide vaccine, containing 16 amino acid residues (611-626) of the human telomerase reverse transcriptase catalytic subunit (hTERT), with potential antineoplastic activity. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation. Vaccination with tertomotide may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against telomerase-expressing cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0004345 a rdfs:Class ;
  rdfs:label "HIV DNA vaccine pCMN160" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0002009 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 11A5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0002372 .

obo:VO_0001605 a rdfs:Class ;
  rdfs:label "Avian Pneumovirus Modified Live Virus Vaccine (USDA: 1A31.20)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001514 , obo:VO_0007748 .

obo:VO_0011442 a rdfs:Class ;
  rdfs:label "E. coli C4424 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0019563 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flulaval Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003757 , obo:VO_0019544 .

obo:OBI_0000281 a rdfs:Class ;
  rdfs:label "intraperitoneal injection" ;
  rdfs:comment "is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe"@en ;
  rdfs:subClassOf obo:OBI_0000426 , obo:OBI_0000429 .

obo:VO_0020054 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Injectable Suspension [FluLaval 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020336 .

obo:VO_0018580 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML Oral Suspension [Rotarix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018579 , obo:VO_0018582 , obo:VO_0018683 .

obo:VO_0001989 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002361 .

obo:VO_0001903 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4145.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002346 .

obo:VO_0015618 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax]" ;
  rdfs:subClassOf obo:VO_0003424 , obo:VO_0015548 .

obo:VO_0016002 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0003424 .

obo:VO_0003883 a rdfs:Class ;
  rdfs:label "Flublok 2014-2015 Formula Injectable Product" ;
  rdfs:subClassOf obo:VO_0003882 .

obo:VO_0004765 a rdfs:Class ;
  rdfs:label "rORFV-D1701-V-HAh5n (H5N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0015862 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax] Box of 25" ;
  rdfs:subClassOf obo:VO_0015612 , obo:VO_0015680 , obo:VO_0015990 .

obo:VO_0003110 a rdfs:Class ;
  rdfs:label "Rabie-Vax vaccine" ;
  rdfs:comment "A vaccine for indivuduals who at risk or recently exposed to rabies." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010448 .

obo:VO_0002895 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium IppA/IppB/msbB vaccine" ;
  rdfs:comment "An lppA mutant, in combination with an lppB/msbB mutation, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:OPL_0000374 a rdfs:Class ;
  rdfs:label "Plasmodium vivax lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Plasmodium vivax." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0019755 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020495 .

obo:NCBITaxon_70999 a rdfs:Class ;
  rdfs:label "Triatominae" ;
  rdfs:subClassOf obo:NCBITaxon_33340 .

obo:VO_0002840 a rdfs:Class ;
  rdfs:label "Francisella tularensis capB mutant vaccine" ;
  rdfs:comment "There was a deletion in gene capB of F. tularensis live vaccine strain. LVS capB, while much less virulent than LVS, induces potent protective immunity against lethal LVS i.n. challenge in mice, comparable to that induced by LVS" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0019922 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Nasal Spray [Flumist 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019921 , obo:VO_0020349 .

obo:VO_0007020 a rdfs:Class ;
  rdfs:label "STn-KLH plus Detox Vaccine" ;
  rdfs:comment "A vaccine comprised of a synthetic Sialyl-Tn antigen linked to the protein carrier, keyhole limpet hemocyanin (KLH), administered with immunostimulant, Detox. Vaccination with STn-KLH plus Detox may elicit an IgG-based anti-STn antibody response and ultimately a cytotoxic T-cell response against STn-expressing cancer cells." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0016808 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Pur] Box of 2" ;
  rdfs:subClassOf obo:VO_0016728 , obo:VO_0016750 , obo:VO_0016820 .

obo:OBI_0302729 a rdfs:Class ;
  rdfs:label "chemical solution"@en ;
  rdfs:comment "A material entity  that is made up of at least 2 scattered molecular aggregates, one playing the role of solvent and the other one playing the role of solute."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0001584 a rdfs:Class ;
  rdfs:label "Wart Killed Virus Vaccine (USDA: 1985.50)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001491 .

obo:VO_0011021 a rdfs:Class ;
  rdfs:label "CP" ;
  rdfs:comment "Following a booster vaccination, a significant (P < 0.05) IgG antibody response to the CP (cps5C), LPS, and HP was detected in the vaccinated pigs. The pigs vaccinated with the CP-HP and LPS-HP conjugates exhibited significantly less mortality (P < 0.05) and significantly greater weight gain (P < 0.001) than unvaccinated pigs. Vaccinated pigs exhibited significantly fewer and less extensive gross pulmonary lesions (P < 0.001) when compared with unvaccinated pigs [PubMed: 1455686]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010821 .

obo:VO_0010491 a rdfs:Class ;
  rdfs:label "licensed human Parainfluenza 3 virus vaccine" ;
  rdfs:comment "Parainfluenza 3 virus vaccine is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000451 , obo:VO_0000455 , obo:VO_0000635 .

obo:VO_0000301 a rdfs:Class ;
  rdfs:label "pRc/CMV DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002406 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Measles-Parainfluenza Vaccine" ;
  rdfs:subClassOf obo:VO_0000654 , obo:VO_0002407 .

obo:VO_0005136 a rdfs:Class ;
  rdfs:label "Ad41.MERS vaccine" ;
  rdfs:comment "A MERS recombinant vector made of Adenovirus type 41 used as vector for MERS-CoV S protein." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:UBERON_0001044 a rdfs:Class ;
  rdfs:label "saliva-secreting gland" ;
  rdfs:comment "Saliva-secreting exocrine glands of the oral cavity[GO]." ;
  rdfs:subClassOf obo:UBERON_0010047 .

obo:VO_0016617 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0016559 .

obo:VO_0019335 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML / meningococcal polysaccharide vaccine group W-135 0.1 MG/ML / meningococcal polysaccharide vaccine group Y 0.1 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0020126 .

obo:VO_0017675 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen (isoform S), recombinant 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0000676 a rdfs:Class ;
  rdfs:label "Shigella dysenteriae 1 strain WRSd1 vaccine" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ;
  rdfs:subClassOf obo:VO_0000681 .

obo:VO_0004803 a rdfs:Class ;
  rdfs:label "LM1-2-E7 vaccine" ;
  rdfs:subClassOf obo:VO_0000667 .

obo:VO_0010743 a rdfs:Class ;
  rdfs:label "Twinrix Junior vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000745 .

obo:VO_0019780 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0010777 a rdfs:Class ;
  rdfs:label "Shigella protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0003492 a rdfs:Class ;
  rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010305 , obo:VO_0010415 .

obo:VO_0000316 a rdfs:Class ;
  rdfs:label "pSG5 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0020681 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus / Influenza Virus Vaccine, Inactivated A-Christchurch-16-2010 NIB-74 (H1N1) (A-California-7-2009) strain / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain Injectable Suspension [Fluarix]" ;
  rdfs:subClassOf obo:VO_0000045 , obo:VO_0020680 .

obo:VO_0007378 a rdfs:Class ;
  rdfs:label "DNA Vaccine VB10.16" ;
  rdfs:comment "A therapeutic DNA vaccine composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type 16 (HPV16), the second is a dimerization entity and the third part encodes a protein that specifically binds to antigen presenting cells (APCs), with potential immunostimulating and antineoplastic activities. Upon intramuscular administration, the DNA vaccine VB10.16 expresses HPV16 E6/7 and a protein that targets receptors on APCs. Upon binding to APCs and subsequent internalization, the APCs mature and the HPV16 E6/7 antigenic protein is presented by the APCs. This attracts and stimulates B-lymphocytes, CD4-positive T-lymphocytes and elicits a cytotoxic T-lymphocyte (CTL) response against cancer cells expressing HPV16-associated E6 and E7 oncoproteins, which result in tumor cell lysis. HPV16 E6/7, a viral antigen, plays a key role in the development of certain types of cancer." ;
  rdfs:subClassOf obo:VO_0005488 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0019394 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.08 MG/ML / diphtheria toxoid vaccine, inactivated 18 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017799 , obo:VO_0018770 .

obo:VO_0007497 a rdfs:Class ;
  rdfs:label "hTERT/survivin/melanoma tumor cell-derived mRNA-transfected dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine containing dendritic cells (DCs) that are transfected with messenger RNA (mRNA) encoding human telomerase reverse transcriptase (hTERT) and survivin in addition to patient-specific melanoma-derived mRNA with potential immunostimulatory and antineoplastic activities. Upon administration, hTERT/survivin/melanoma tumor cell-derived mRNA-transfected dendritic cell vaccine may elicit a highly specific cytotoxic T-cell (CTL) response against melanoma cells expressing hTERT, survivin, and patient-specific melanoma-associated antigens. hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types, playing key roles in tumor cell growth and survival. " ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020644 a rdfs:Class ;
  rdfs:label "1 ML BCG, live, Connaught strain 20000 UNT/ML Injectable Solution Box of 10 by AJ Vaccines" ;
  rdfs:subClassOf obo:VO_0020643 .

obo:VO_0018230 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Prefilled Syringe [Priorix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018229 , obo:VO_0018231 .

obo:VO_0000368 a rdfs:Class ;
  rdfs:label "live vaccine organism" ;
  rdfs:comment "a vaccine organism that is live" ;
  rdfs:subClassOf obo:VO_0000506 .

obo:VO_0001696 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1651.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0021134 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0012361 a rdfs:Class ;
  rdfs:label "PcrV" ;
  rdfs:comment "Burned Pseudomonas aeruginosa-infected mice immunized against PcrV, a type III virulence system translocating protein, showed significantly enhanced survival compared to controls [PubMed: 11500471]." ;
  rdfs:subClassOf obo:VO_0012370 .

obo:VO_0007513 a rdfs:Class ;
  rdfs:label "cyclin B1/WT-1/CEF-loaded DC vaccine" ;
  rdfs:comment "A cancer vaccine for patients with Locally Advanced, Triple-Negative Breast Cancer or ER-Positive, Her2-Negative Breast Cancer to receive ex vivo-generated tumor antigen-loaded dendritic cells (DCs), which can prime lymphocytes and regulate and maintain immune responses. The vaccine may boost T cell immunity targeted against breast cancer, enhance chemotherapy effectiveness and decrease tumor metastagenicity, and decrease the recurrence rates of LA TNBC and ER+/HER2- BC. " ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0002181 a rdfs:Class ;
  rdfs:label "Newcastle Disease-Fowl Pox Live Fowl Pox Vector Vaccine (USDA: 17C1.R0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002456 , obo:VO_0007748 .

obo:VO_0017957 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 2.5 MG / meningococcal group C polysaccharide 2.5 MG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 2.5 MG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 2.5 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017819 .

obo:VO_0011291 a rdfs:Class ;
  rdfs:label "M2" ;
  rdfs:comment "Immunization of CBA mice with the M-2 glycoprotein of L. amazonensis and C. parvum adjuvant resulted in complete protection against a challenge infection of 10^4 and 10^6 late log-phase promastigotes of L. amazonensis. In the BALB/c strain, complete protection was observed in some of the immunized animals (28 to 50%); in the rest of the mice the onset of infection was significantly delayed. Protective immunity for C57BL/6 mice was observed only at the low infecting dose (10(4) L. amazonensis organisms) [PubMed: 3182080]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010837 .

obo:VO_0003373 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003372 .

obo:VO_0019302 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Afluria 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019301 , obo:VO_0020300 .

obo:VO_0004413 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi DNA vaccine pCMV-ZS7/TPA encoding OspC from Borrelia burgdorferi sensu lato" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000764 .

obo:VO_0004140 a rdfs:Class ;
  rdfs:label "Broilact Chick Salmonella vaccine" ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0007060 a rdfs:Class ;
  rdfs:label "pNGVL4a-CRT/E7(detox) DNA vaccine" ;
  rdfs:comment "A cancer vaccine consisting of the DNA plasmid pNGVL4a-A encoding calreticulin (CRT) linked to a detox form of human papillomavirus (HPV) type 16 E7 antigen, with potential immunomodulating and antineoplastic activities. Upon administration, this vaccine may generate a potent cytotoxic T-lymphocyte (CTL) response against E7-expressing tumor cells, resulting in tumor cell death. For E7(detox), the amino acids in E7 at positions 24 (cysteine to glycine) and 26 (glutamic acid to glycine) were substituted. CRT, a 46 kDa protein located in the lumen of the cell's endoplasmic reticulum (ER), may potentiate MHC class I presentation of HPV-16 E7 to E7-specific CD8-positive T cells. In addition, pNGVL4a-A contains two short immunostimulatory DNA sequences (ISS) in the noncoding region, which may elicit the production of IFN- and IL-12 in transfected keratinocytes and dermal antigen presenting cells (APCs), resulting in a potent T helper cell type 1 response." ;
  rdfs:subClassOf obo:VO_0005488 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0005121 a rdfs:Class ;
  rdfs:label "MERS rRBD plus alum vaccine" ;
  rdfs:comment "A MERS subunit vaccine made of neutralizing monoclonal antibodiesagainst MERS-CoV which bind to the ribosomal binding domain (RBD) of the MERS-CoV S protein that was expressed by baculovirus-insect cell sf9-derived recombinant MERS-CoV." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0000865 a rdfs:Class ;
  rdfs:label "Porphyromonas gulae vaccine" ;
  rdfs:comment "Vaccine that protects against Porphyromonas gulae infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0001180 a rdfs:Class ;
  rdfs:label "laboratory test" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0017122 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017580 .

obo:DOID_201 a rdfs:Class ;
  rdfs:label "connective tissue cancer"@en ;
  rdfs:comment "A musculoskeletal system cancer that is located_in connective tissue."@en ;
  rdfs:subClassOf obo:DOID_0060100 , obo:DOID_65 .

obo:VO_0005303 a rdfs:Class ;
  rdfs:label "2F52 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0003812 a rdfs:Class ;
  rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010311 , obo:VO_0010415 .

obo:VO_0003469 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010302 , obo:VO_0010415 .

obo:VO_0007249 a rdfs:Class ;
  rdfs:label "ALVAC(2) Melanoma multi-antigen vaccine" ;
  rdfs:comment "A therapeutic cancer vaccine, based on a replication-defective recombinant canarypox virus (ALVAC) encoding multiple melanoma antigens, with potential immunostimulatory and antineoplastic activities. Vaccination with ALVAC(2) melanoma multi-antigen therapeutic vaccine may stimulate the host immune system to mount an immune response against antigen-expressing melanoma cells, resulting in inhibition of tumor growth and/or metastasis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0007594 a rdfs:Class ;
  rdfs:label "Contusugene ladenovec vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0011521 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii Subunit Rop2-Hsp83 fusion protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000994 .

obo:VO_0016439 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0018857 a rdfs:Class ;
  rdfs:label "influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010301 , obo:VO_0010415 .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role"@en ;
  rdfs:comment "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:VO_0004486 a rdfs:Class ;
  rdfs:label "Vaccinia virus DNA vaccine wtD8L" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000651 .

obo:DOID_9682 a rdfs:Class ;
  rdfs:label "yellow fever"@en ;
  rdfs:comment "A viral infectious disease that results in infection, has_material_basis_in Yellow fever virus (Orthoflavivirus flavi), which is transmitted by Aedes, transmitted by Haemagogus, or transmitted by Sabethes species of mosquitoes. The infection has symptom fever, has symptom muscle pain, has symptom backache, has symptom headache, has symptom shivers, has symptom loss of appetite, has symptom jaundice, and has symptom bleeding from the mouth, nose, eyes or stomach leading to vomitus containing blood."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0015185 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0015180 , obo:VO_0015190 , obo:VO_0015271 .

obo:VO_0015985 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015650 , obo:VO_0015768 .

obo:VO_0001663 a rdfs:Class ;
  rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.50)" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:VO_0001477 a rdfs:Class ;
  rdfs:label "salmoninae vaccine" ;
  rdfs:comment "Vaccine that used for immunizing  salmoninae (tourts, salmons & chars)." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001462 .

obo:VO_0007539 a rdfs:Class ;
  rdfs:label "MAGE-A3 peptide vaccine" ;
  rdfs:comment "A peptide cancer vaccine comprised of a peptide derived from the human melanoma antigen A3 (MAGE-A3), with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-A3 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-A3, resulting in tumor cell lysis. MAGE-A3, a tumor-associated antigen (TAA), is overexpressed by a variety of cancer cell types." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0001957 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C7.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002361 .

obo:VO_0001258 a rdfs:Class ;
  rdfs:label "amelioration of disorder objective" ;
  rdfs:comment "The specification of an objective to ameliorate  a disorder." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:VO_0000677 a rdfs:Class ;
  rdfs:label "Shigella flexneri 2a strain CVD 1207 vaccine" ;
  rdfs:comment "A  live attenuated Shigella flexneri 2a vaccine with specific deletion mutations in virG, sen, set, and guaBA." ;
  rdfs:subClassOf obo:VO_0000680 , obo:VO_0001217 .

obo:VO_0018187 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus Injection [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0000069 , obo:VO_0018186 .

obo:VO_0016834 a rdfs:Class ;
  rdfs:label "10 ML diphtheria toxoid vaccine, inactivated 0.5 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016758 .

obo:VO_0019454 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0002729 a rdfs:Class ;
  rdfs:label "NV from Infectious Hematopoietic Necrosis Virus" ;
  rdfs:comment "A mutation in the non-virion protein of IHNV causes attenuated growth in rainbow trout and is able to provide significant protection from subsequent challenge with wild type IHNV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001440 .

obo:NCBITaxon_633 a rdfs:Class ;
  rdfs:label "Yersinia pseudotuberculosis" ;
  rdfs:subClassOf obo:NCBITaxon_1649845 .

obo:VO_0005237 a rdfs:Class ;
  rdfs:label "SpFN vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Walter Reed Army Institute of Research" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:OPL_0000277 a rdfs:Class ;
  rdfs:label "Plasmodium hepatic schizont" ;
  rdfs:comment "A Plasmodium schizont that is found in infected hepatocytes (i.e. liver cells) of a vertebrate host." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000275 .

obo:VO_0010059 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi SSP2" ;
  rdfs:comment "A PkSSP2 protein that is part of Plasmodium knowlesi|A SSP2 protein that is part of Plasmodium knowlesi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015472 .

obo:VO_0011069 a rdfs:Class ;
  rdfs:label "Gag" ;
  rdfs:comment "The vaccine, (EURIFEL FeLV; Merial) that expresses the FeLV env and gag protective genes, is effective against any oronasal FeLV challenge. The protection was shown to be solid against an oronasal challenge one year after the initial vaccination, and was effective against a very severe 'in-contact' challenge [PubMed: 12934796]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010806 .

obo:GO_0071753 a rdfs:Class ;
  rdfs:label "IgM immunoglobulin complex" ;
  rdfs:comment "A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ;
  rdfs:subClassOf obo:GO_0019814 .

obo:VO_0019620 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020332 .

obo:VO_0017457 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010447 , obo:VO_0017674 .

obo:VO_0021164 a rdfs:Class ;
  rdfs:label "zoster vaccine, live" ;
  rdfs:comment "A varicella-zoster virus live vaccine designed to prevent shingles (herpes zoster). " ;
  rdfs:subClassOf obo:VO_0000419 , obo:VO_0000455 , obo:VO_0000635 .

obo:VO_0019183 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010420 .

obo:VO_0016302 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015926 .

obo:VO_0010784 a rdfs:Class ;
  rdfs:label "Measles virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0003813 a rdfs:Class ;
  rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML [Flumist Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003807 .

obo:VO_0018345 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003335 .

obo:VO_0011349 a rdfs:Class ;
  rdfs:label "Leishmania amazonensis DNA vaccine encoding WD protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012158 .

obo:VO_0010812 a rdfs:Class ;
  rdfs:label "Porphyromonas gulae protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0002264 a rdfs:Class ;
  rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.01)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002420 , obo:VO_0007748 .

obo:VO_0002420 a rdfs:Class ;
  rdfs:label "equine EEV and WEV encephalomyelitis vaccine-tetanus toxoid" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000639 , obo:VO_0001472 , obo:VO_0001498 , obo:VO_0012188 .

obo:NCBITaxon_518 a rdfs:Class ;
  rdfs:label "Bordetella bronchiseptica" ;
  rdfs:subClassOf obo:NCBITaxon_517 .

obo:VO_0005013 a rdfs:Class ;
  rdfs:label "WRG/BEN DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label WRG/BEN.  This plasmid is based off of pWRG7077.  It contains a CMV promoter and a kanamycin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:OPL_0000121 a rdfs:Class ;
  rdfs:label "Anopheles salivary gland" ;
  rdfs:comment "A salivary gland that is a part of or originated from an Anopheles mosquito." ;
  rdfs:subClassOf obo:UBERON_0001044 .

obo:VO_0011279 a rdfs:Class ;
  rdfs:label "PSA-2" ;
  rdfs:comment "Intraperitoneal vaccination of C3H/He mice with PSA-2 with Corynebacterium parvum as an adjuvant resulted in complete protection from lesion development after challenge infection with virulent L. major. Significant protection was also obtained in the genetically susceptible BALB/cH-2k and BALB/c mice [PubMed: 7591056]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0000522 a rdfs:Class ;
  rdfs:label "DAAV using PA and PGA vaccine" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0004403 a rdfs:Class ;
  rdfs:label "Autoimmune diabetes DNA vaccine pND2-SGAD55" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002811 .

obo:VO_0002171 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1785.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0004893 a rdfs:Class ;
  rdfs:label "Fluenz vaccine" ;
  rdfs:comment "Fluenz is a seasonal trivalent live attenuated influenza vaccine (LAIV) administered intranasally. The vaccine contained A/California/07/2009 (H1N1) pdm09-like strain, A/Victoria/361/2011 (H3N2)-like strain, and B/Massachusetts/2/2012-like strain." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000642 , obo:VO_0001178 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0019668 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020324 .

obo:VO_0002383 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Vaccine" ;
  rdfs:subClassOf obo:VO_0002367 , obo:VO_0002385 .

obo:VO_0005053 a rdfs:Class ;
  rdfs:label "pEGFP-N1 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pEGFP-N1.  This plasmid is 4733 base pairs in length and contains a CMV promoter and kanamycin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0010861 a rdfs:Class ;
  rdfs:label "VP40 from Reston ebolavirus" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0003327 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 22F vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003227 .

obo:VO_0020803 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 UNT Injectable Solution [OncoTICE] by Merck" ;
  rdfs:subClassOf obo:VO_0020802 .

obo:VO_0021045 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Suspension [Zostavax]" ;
  rdfs:subClassOf obo:VO_0000124 , obo:VO_0021044 .

obo:NCBITaxon_3052225 a rdfs:Class ;
  rdfs:label "Henipavirus nipahense" ;
  rdfs:subClassOf obo:NCBITaxon_260964 .

obo:VO_0016607 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0016559 .

obo:VO_0007457 a rdfs:Class ;
  rdfs:label "Mouse Prostate-Specific Membrane Antigen Plasmid DNA Vaccine" ;
  rdfs:comment "A vaccine consisting of a plasmid DNA encoding the murine prostate-specific membrane antigen (PSMA). Upon administration, expressed PSMA may stimulate a cytotoxic T cell response against tumor cells that express PSMA, resulting in tumor cell lysis" ;
  rdfs:subClassOf obo:VO_0005494 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0016567 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Twinrix Paediatric]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0016557 .

obo:VO_0019675 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0000410 a rdfs:Class ;
  rdfs:label "Pandemrix vaccine" ;
  rdfs:comment "Pandemrix is an influenza vaccine for influenza pandemics, such as the H1N1 2009 flu pandemic colloquially called the swine flu. The vaccine was developed by GlaxoSmithKline and patented in September 2006." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0000642 , obo:VO_0010415 .

obo:VO_0000125 a rdfs:Class ;
  rdfs:label "licensed turkey vaccine" ;
  rdfs:subClassOf obo:VO_0000657 , obo:VO_0001478 .

obo:VO_0004867 a rdfs:Class ;
  rdfs:label "MENHIBRIX vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0004865 , obo:VO_0020832 .

obo:VO_0001826 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.12)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0002477 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0000436 a rdfs:Class ;
  rdfs:label "Brucella melitensis DNA vaccine encoding Omp31 boosted with Omp31" ;
  rdfs:subClassOf obo:VO_0001226 .

obo:VO_0002939 a rdfs:Class ;
  rdfs:label "Yersinia pestis guaBA mutant vaccine" ;
  rdfs:comment "A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0003635 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016-2017 vaccine 0.1 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003634 .

obo:VO_0018641 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injection [Jespect]" ;
  rdfs:subClassOf obo:VO_0018640 .

obo:VO_0003661 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010313 , obo:VO_0010415 .

obo:OPL_0000115 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum sporozoite stage" ;
  rdfs:comment "A sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the human host." ;
  rdfs:subClassOf obo:OPL_0000152 , obo:OPL_0000165 , obo:OPL_0000300 .

obo:VO_0001210 a rdfs:Class ;
  rdfs:label "lipopolysaccharide subunit vaccine" ;
  rdfs:comment "a subunit vaccien that uses LPS as protective antigen" ;
  rdfs:subClassOf obo:VO_0000534 .

obo:VO_0002522 a rdfs:Class ;
  rdfs:label "apxIIID from Actinobacillus pleuropneumoniae" ;
  rdfs:comment "An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001384 .

obo:VO_0002701 a rdfs:Class ;
  rdfs:label "glycoprotein G from Bovine Respiratory Syncytial Virus" ;
  rdfs:comment "A glycoprotein G deletion in bovine respiratory syncytial virus(rBRSV) and recombinant rBRSV was attenuated and provided protection against a BRSV challenge infection in calves" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001429 .

obo:VO_0011252 a rdfs:Class ;
  rdfs:label "E (envelope glycoprotein)" ;
  rdfs:comment "A recombinant, vP869, expressing prM and E induced high titers of neutralizing and hemagglutination inhibiting antibodies in mice and was protective against intracranial challenge with the French neurotropic strain of YFV [PubMed: 1736531]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010791 .

obo:VO_0007660 a rdfs:Class ;
  rdfs:label "DNA cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is composed of a plasmid vaccine vector (a circular double stranded DNA molecule) containing the whole of parts of genes encoding one or more vaccine antigen proteins." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000177 .

obo:VO_0017167 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] Box of 2 by Novartis" ;
  rdfs:subClassOf obo:VO_0017166 .

obo:VO_0007524 a rdfs:Class ;
  rdfs:label "Melapuldencel-T vaccine" ;
  rdfs:comment "A therapeutic melanoma vaccine consisting of autologous dendritic cells (DCs) pulsed with antigens from lethally irradiated autologous tumor cells derived from a patient-specific, continuously proliferating and melanoma-initiating cell line and suspended in a solution containing the cytokine granulocyte-macrophage colony stimulating factor (GM-CSF), with potential immunostimulatory and antineoplastic activities. Upon subcutaneous administration, melapuldencel-T may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against the patient's repertoire of melanoma-associated antigens, particularly tumor stem cell antigens, found in the irradiated autologous cancer cells. As an immunostimulant, GM-CSF enhances the activation of dendritic cells (DCs) and promotes antigen presentation to both B- and T-lymphocytes." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0015916 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015629 , obo:VO_0015677 , obo:VO_0016024 .

obo:VO_0019814 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017226 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0017225 .

obo:VO_0002783 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis lysA/secA2 mutant vaccine" ;
  rdfs:comment "A lysA mutant, in combination with a secA2 mutation, is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0018241 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 20000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0018239 , obo:VO_0018240 .

obo:VO_0007516 a rdfs:Class ;
  rdfs:label "dendritic cell tumor peptide vaccine" ;
  rdfs:comment "A cancer vaccine composed of dendritic cells pulsed with peptide epitopes that stimulate cytotoxic T lymphocyte anti-tumor activity. This vaccine is used to treat diffuse hemispheric glioma with a H3 G34 mutation that has come back (recurrent) and/or is growing, spreading, or getting worse (progressive). It is made with the patient's own white blood cells and peptide-pulsed dendritic cells, which may help the body build an effective immune response to kill tumor cells. It is combined with immunotherapy monoclonal antibodies, such as nivolumab and ipilimumab, which also may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread." ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0016527 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0004165 a rdfs:Class ;
  rdfs:label "CCPS-P64kR vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0011479 a rdfs:Class ;
  rdfs:label "Helicobacter pylori VacA protein vaccine" ;
  rdfs:subClassOf obo:VO_0012181 .

obo:VO_0011360 a rdfs:Class ;
  rdfs:label "Vibrio cholerae CTB DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000763 .

obo:VO_0001804 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine (USDA: 19S1.21)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001511 , obo:VO_0007748 .

obo:VO_0000079 a rdfs:Class ;
  rdfs:label "Fluzone High-dose" ;
  rdfs:comment "an influenza vaccine that is similar to Fluzone but has high dose. " ;
  rdfs:subClassOf obo:VO_0000047 .

obo:VO_0001191 a rdfs:Class ;
  rdfs:label "vaccine protective antigen datum" ;
  rdfs:comment "A measurement datum that represents a specific protective antigen used in a vaccine. The antigen can be represented by a described digit. " ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0020893 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Grippe-Impfstoff Stada]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:DOID_2123 a rdfs:Class ;
  rdfs:label "tularemia"@en ;
  rdfs:comment "A primary bacterial infectious disease that has_material_basis_in Francisella tularensis, which is transmitted by dog tick bite (Dermacentor variabilis), transmitted by deer flies (Chrysops sp) or transmitted by contact with infected animal tissues."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:VO_0019623 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020335 .

obo:VO_0020633 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 PFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0021026 .

obo:VO_0011060 a rdfs:Class ;
  rdfs:label "OmlA" ;
  rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.  CP #7 (omlA) was significantly more protective than the genes encoding fewer than 50 amino acids (p-value of less than 0.05 when comparing lung weights). The chlamydial loads generally tracked with protection and the most protective genes were significantly lower than in unvaccinated controls (p < 0.05 in the Mannhitney U-test for genes CP #1, 2, 4, 9, 10) [PubMed: 15811648]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:GO_0008150 a rdfs:Class ;
  rdfs:label "biological_process" ;
  rdfs:comment "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0018921 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:OBI_0000984 a rdfs:Class ;
  rdfs:label "dose" ;
  rdfs:comment "A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:NCBITaxon_9682 a rdfs:Class ;
  rdfs:label "Felis" ;
  rdfs:subClassOf obo:NCBITaxon_33554 .

obo:NCBITaxon_9479 a rdfs:Class ;
  rdfs:label "Platyrrhini" ;
  rdfs:subClassOf obo:NCBITaxon_314293 .

obo:VO_0017405 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 4 LFU/ML Injection" ;
  rdfs:subClassOf obo:VO_0017670 .

obo:VO_0017629 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017610 .

obo:VO_0017541 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution [Tetamun] Box of 10" ;
  rdfs:subClassOf obo:VO_0017539 , obo:VO_0017543 .

obo:NCBITaxon_8825 a rdfs:Class ;
  rdfs:label "Neognathae" ;
  rdfs:subClassOf obo:NCBITaxon_8782 .

obo:VO_0000199 a rdfs:Class ;
  rdfs:label "Rubella virus gene" ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0007639 a rdfs:Class ;
  rdfs:label "mCRT-vGPCR-coated whole-cell vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0011122 a rdfs:Class ;
  rdfs:label "NP from Influenza A virus (A/Puerto Rico/8/34(H1N1))" ;
  rdfs:comment "A simian adenovirus 24 (AdC7) vector expressing the influenza A/Puerto Rico/8/34 NP was tested for its efficacy in protecting BALB/c mice against two H5N1 strains.  When tested in a mouse challenge model, there was a significantly improved survival rate following challenge with the Vietnam/1203/04 strain of H5N1 that has caused human outbreaks [PubMed: 17728024]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0004870 a rdfs:Class ;
  rdfs:label "Menomune A/C/Y/W-135 Injectable Product" ;
  rdfs:subClassOf obo:VO_0000072 .

obo:VO_0017900 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine Injection" ;
  rdfs:subClassOf obo:VO_0004837 .

obo:VO_0020440 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 1" ;
  rdfs:subClassOf obo:VO_0020408 , obo:VO_0020416 .

obo:VO_0003045 a rdfs:Class ;
  rdfs:label "obsolete RB51 induced protection against B.suis" .

obo:VO_0016236 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 50 by Mtk" ;
  rdfs:subClassOf obo:VO_0015907 .

obo:VO_0001338 a rdfs:Class ;
  rdfs:label "Bupivacaine vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is a local anaesthetic drug belonging to the amino amide group, and is used as a vaccine adjuvant in DNA vaccines." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0003395 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 30 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0000230 a rdfs:Class ;
  rdfs:label "pCMV-LIC DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016595 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016584 .

obo:VO_0005248 a rdfs:Class ;
  rdfs:label "COVID-19 subunit vaccine by National Vaccine and Serum Institute of China" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine developed by the National Vaccine and Serum Institute of China" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0007610 a rdfs:Class ;
  rdfs:label "GVAX pancreatic cancer vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0000913 a rdfs:Class ;
  rdfs:label "latex vaccine allergen" ;
  rdfs:subClassOf obo:VO_0000910 .

obo:VO_0019591 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019584 , obo:VO_0020495 .

obo:VO_0015174 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015148 , obo:VO_0015241 .

obo:VO_0015978 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10" ;
  rdfs:subClassOf obo:VO_0003264 .

obo:OPL_0000138 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum oocyst" ;
  rdfs:comment "A Plasmodium falciparum that oocyst is formed, after traversal of the midgut wall by the ookinete stage, on the hemocoel side of the midgut wall of the mosquito vector." ;
  rdfs:subClassOf obo:NCBITaxon_5833 , obo:OPL_0000273 .

obo:VO_0010316 a rdfs:Class ;
  rdfs:label "influenza B virus B/Maryland/15/2016 antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003519 , obo:VO_0010301 .

obo:VO_0005114 a rdfs:Class ;
  rdfs:label "beta-propiolactone-inactivated SARS-CoV vaccine" ;
  rdfs:comment "A SARS inactivated vaccine made from whole killed (inactivated by beta-propiolactone) SARS-CoV" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0012183 .

obo:VO_0017468 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 1.5 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017467 , obo:VO_0017469 .

obo:VO_0020540 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Afluria] Box of 10" ;
  rdfs:subClassOf obo:VO_0020539 , obo:VO_0020603 , obo:VO_0020853 .

obo:VO_0020185 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 667000 UNT/ML Oral Suspension" ;
  rdfs:subClassOf obo:VO_0020183 , obo:VO_0020187 .

obo:VO_0004481 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine PA83 furin" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0018784 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 4 LFU/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0004907 a rdfs:Class ;
  rdfs:label "MERS-CoV S protein" ;
  rdfs:subClassOf obo:VO_0004906 .

obo:VO_0003096 a rdfs:Class ;
  rdfs:label "Ditanrix vaccine" ;
  rdfs:comment "a Diphthpheria-Tetanus Absorbed vaccine for children 7 years of age and adults." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001217 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0016048 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0015670 , obo:VO_0015803 .

obo:VO_0011208 a rdfs:Class ;
  rdfs:label "F fusion protein from Newcastle disease virus" ;
  rdfs:comment "A recombinant fowlpox virus expressing the fusion protein of Newcastle disease virus strain F48E8 protected chickens against virulent NDV challenge.  The protective rate was 96.7% [PubMed: 11191764]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010805 .

obo:VO_0019944 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluarix 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020318 .

obo:VO_0020349 a rdfs:Class ;
  rdfs:label "Flumist 2012-2013 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000044 , obo:VO_0010418 .

obo:VO_0005102 a rdfs:Class ;
  rdfs:label "SARS M protein DNA vaccine" ;
  rdfs:comment "A SARS  DNA vaccine that is made from recombinant plasmid containing membrane protein (M) sequence constructed then expressed and purified from E. coli bacteria." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012183 .

obo:VO_0015146 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine, Inactivated 320 UNT/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution [Vivaxim]" ;
  rdfs:subClassOf obo:VO_0015145 , obo:VO_0015332 .

obo:VO_0010903 a rdfs:Class ;
  rdfs:label "BoNT/A1 from C. botulinum A str. Hall" ;
  rdfs:comment "Mice and rabbits were immunized with recombinant HCR/A1 (rHCR/A1) from the classical type A-Hall strain (ATCC 3502) (BoNT/A1) and rHCR/E from BoNT serotype E Beluga (BoNT/E(B)).  The protection elicited by rHCR/A1 to BoNT/A1 and BoNT/A2 and by rHCR/E(B) to BoNT/E(A) indicate that immunization with receptor binding domains elicit protection within sub-serotypes of BoNT [PubMed: 16177380]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010762 .

obo:VO_0001842 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1A69.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002432 , obo:VO_0007748 .

obo:VO_0002366 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona-Mannheimia Haemolytica Bacterin" ;
  rdfs:subClassOf obo:VO_0001523 , obo:VO_0002364 .

obo:VO_0002884 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Enteritidis guaBA/clpP mutant vaccine" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective in mice and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis" .

obo:VO_0018906 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0011468 a rdfs:Class ;
  rdfs:label "Shigella flexneri Invaplex 50 subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000680 .

obo:VO_0016447 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0018585 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML Oral Suspension [Rotarix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018584 , obo:VO_0018587 , obo:VO_0018689 .

obo:VO_0020397 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 10000000000 UNT Delayed Release Oral Capsule" ;
  rdfs:subClassOf obo:VO_0020369 .

obo:VO_0019162 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Quadracel]" ;
  rdfs:subClassOf obo:VO_0000744 , obo:VO_0010437 , obo:VO_0010736 .

obo:OBI_0000838 a rdfs:Class ;
  rdfs:label "material maintenance" ;
  rdfs:comment "A planned process with the objective to maintain some or all of the characteristics of an input material over time."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0003582 a rdfs:Class ;
  rdfs:label "Fluzone 2015-2016 High-Dose vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003581 .

obo:VO_0016229 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015906 .

obo:VO_0002736 a rdfs:Class ;
  rdfs:label "gp50 from Pseudorabies virus" ;
  rdfs:comment "A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky's disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001442 .

obo:VO_0004515 a rdfs:Class ;
  rdfs:label "pCgap DNA vaccine encoding glyceraldehyde-3-phosphate dehydrogenase" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000611 .

obo:VO_0003085 a rdfs:Class ;
  rdfs:label "Adacel-Polio vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000742 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0018773 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.025 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0004851 a rdfs:Class ;
  rdfs:label "Bexsero Injectable Product" ;
  rdfs:subClassOf obo:VO_0003066 .

obo:VO_0010111 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii ROP16" ;
  rdfs:comment "A ROP16 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0002907 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine" ;
  rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" .

obo:VO_0016433 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0019504 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine (inactivated) strain HM175 720 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003434 .

obo:VO_0005183 a rdfs:Class ;
  rdfs:label "CORVax12 vaccine" ;
  rdfs:comment "A SARS-CoV-2 DNA vaccine developed by Providence Health & Services." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0003981 a rdfs:Class ;
  rdfs:label "Daptacel Injectable Product" ;
  rdfs:subClassOf obo:VO_0000029 .

obo:VO_0016968 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 50 LFU/ML / Pertussis Vaccine 24 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 160 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017425 .

obo:VO_0020391 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix]" ;
  rdfs:subClassOf obo:VO_0020360 , obo:VO_0020469 .

obo:VO_0011043 a rdfs:Class ;
  rdfs:label "UL44 from Bovine herpesvirus 1" ;
  rdfs:comment "A DNA vaccine expressing glycoprotein C (gC, UL44) of bovine herpesvirus-1 (BHV-1) was evaluated for inducing immunity in bovines.  Results indicate that DNA immunization with gC could induce neutralizing antibody and lymphoproliferative responses with BHV-1 responsive memory B cells in bovines. However, the immunity developed sufficient for only partial protection against BHV-1 challenge [PubMed: 11182496]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010802 .

obo:UBERON_0000105 a rdfs:Class ;
  rdfs:label "life cycle stage" ;
  rdfs:comment "A spatiotemporal region encompassing some part of the life cycle of an organism." ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:VO_0002974 a rdfs:Class ;
  rdfs:label "Herpes simplex virus 1 UL29 mutant vaccine" ;
  rdfs:comment "A UL29 mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1" ;
  rdfs:subClassOf obo:VO_0000958 .

obo:VO_0017111 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur] Box of 2" ;
  rdfs:subClassOf obo:VO_0017108 , obo:VO_0017117 , obo:VO_0017575 .

obo:VO_0017979 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.03 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec] by Nuron Biotech" ;
  rdfs:subClassOf obo:VO_0017969 .

obo:VO_0015282 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015279 , obo:VO_0019502 .

obo:VO_0016495 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015979 .

obo:VO_0003453 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0004371 a rdfs:Class ;
  rdfs:label "Rabies virus DNA vaccine pCMV-intA-rabies encoding glycoprotein G" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000650 .

obo:VO_0000640 a rdfs:Class ;
  rdfs:label "Clostridium tetani vaccine" ;
  rdfs:comment "a Clostridium vaccine that protects against infection with Clostridium tetani that causes tenanus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000639 .

obo:VO_0002533 a rdfs:Class ;
  rdfs:label "lysA from Mycobacterium tuberculosis" ;
  rdfs:comment "A lysA mutant, in combination with a secA2 mutation, is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0011149 a rdfs:Class ;
  rdfs:label "NS5" ;
  rdfs:comment "Researchers constructed plasmid DNAs encoding JE virus proteins. Cytotoxic T lymphocytes (CTLs) were induced by NS5 in a mouse model. Three immunizations with pUJENS5 provided a 57% partial protection from a lethal dose of JE virus [PubMed: 12922097]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010783 .

obo:VO_0000872 a rdfs:Class ;
  rdfs:label "Babesia bovis vaccine by local veterinary institutes" ;
  rdfs:subClassOf obo:VO_0000925 .

obo:VO_0017485 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [T Immun] Box of 1" ;
  rdfs:subClassOf obo:VO_0017484 , obo:VO_0017496 .

obo:VO_0007693 a rdfs:Class ;
  rdfs:label "mixed bacterial cancer vaccine" ;
  rdfs:comment "A cancer vaccine containing a mixture of killed bacteria with potential immunostimulatory and antineoplastic activities. Mixed bacteria vaccine (MBV or Coley's toxins) consists of a pyrogenic bacterial lysate derived from Serratia marcescens and Streptococcus pyogenes; the active components in the lysate may be lipopolysaccharide (LPS), a component of the Gram-negative bacterial cell wall of Serratia, and streptokinase, an enzyme produced by Streptococcus pyogenes. LPS has been shown to stimulate the host humoral immune response and induce the release of various antitumor cytokines such as tumor necrosis factor (TNF) and interleukin-12 (IL-12). The mixed bacteria vaccine (MBV) is administered at a starting dose of 250 EU (1 µL) and escalated in each patient to a dose inducing the desired pyrogenic effect, defined as a body temperature of 38°C to 39.5°C. It is given to patients with malignant tumors that expressed the NY-ESO-1 antigen. It is designed to induce immunological effects and tumor response following vaccination. " ;
  rdfs:subClassOf obo:VO_0000315 , obo:VO_0007657 .

obo:VO_0003742 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2016-2017 Formula Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003739 .

obo:VO_0004584 a rdfs:Class ;
  rdfs:label "Infectious Bronchitis virus DNA vaccine encoding S1, N, and M" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001502 .

obo:VO_0011268 a rdfs:Class ;
  rdfs:label "DnaJ" ;
  rdfs:comment "Immunisation of mice with DnaJ derived from Salmonella enterica subsp. enterica serovar Typhi str. CT18 was found to provide 70% protection against lethal challenge by S. Typhimurium indicating the possible use of DnaJ as vaccine candidate against typhoid [PubMed: 16887241]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010776 .

obo:VO_0007042 a rdfs:Class ;
  rdfs:label "retrovector encoding mutant Anti-Cyclin G1 vaccine" ;
  rdfs:comment "A replication-incompetent, pathotropic, tumor matrix (collagen)-targeted, retroviral vector encoding an N-terminal deletion mutant form of the cyclin G1 gene with potential antineoplastic activity. Under the control of a hybrid long-terminal repeat/cytomegalovirus (CMV) promoter, retrovector encoding mutant anti-cyclin G expresses the mutant cyclin G1 construct, resulting in disruption of tumor cell cyclin G1 activity and decreased cellular proliferation and angiogenesis. This agent preferentially targets collagen of the tumor matrix because of the incorporation of the collagen-binding domain of von Willebrand factor (vWF) on the retrovector surface. Exploiting the collagen-targeting mechanism of vWF permits delivery of the retrovector to tumor sites where angiogenesis and collagen matrix exposure occur." ;
  rdfs:subClassOf obo:VO_0005430 , obo:VO_0005484 , obo:VO_0005495 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0020418 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 100" ;
  rdfs:subClassOf obo:VO_0020391 , obo:VO_0020428 .

obo:VO_0003861 a rdfs:Class ;
  rdfs:label "1 ML Imovax 2.5 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003859 .

obo:VO_0002827 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei purM mutant vaccine" ;
  rdfs:comment "Mice that were challenged with a higher dose of mutant 56:65 purM were protected" ;
  rdfs:subClassOf obo:VO_0012175 .

obo:VO_0019487 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.265 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003409 .

obo:VO_0017095 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017088 .

obo:VO_0018211 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 12500 UNT / Rubella virus vaccine 1000 UNT Injectable Suspension [M.M.R. VaxPro]" ;
  rdfs:subClassOf obo:VO_0018209 , obo:VO_0018210 .

obo:VO_0004121 a rdfs:Class ;
  rdfs:label "Avirulent Salmonella vaccine strain carrying C. jejuni cjaA gene" ;
  rdfs:subClassOf obo:VO_0012182 .

obo:VO_0017560 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0017556 , obo:VO_0017581 .

obo:NCBITaxon_10242 a rdfs:Class ;
  rdfs:label "Orthopoxvirus" ;
  rdfs:subClassOf obo:NCBITaxon_10241 .

obo:VO_0015963 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 100" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015731 , obo:VO_0015737 , obo:VO_0016047 .

obo:VO_0018656 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection [Cervarix] Box of 20" ;
  rdfs:subClassOf obo:VO_0018654 , obo:VO_0018658 .

obo:VO_0001389 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine encoding TSA-1" ;
  rdfs:comment "A T. cruzi DNA vaccine that uses a DNA plasmid expressing T. cruzi TSA-1 protein." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0020853 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Afluria] Box of 10" ;
  rdfs:subClassOf obo:VO_0020852 , obo:VO_0020884 .

obo:VO_0003996 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 UNT/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 .

obo:VO_0016727 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0016712 , obo:VO_0016733 .

obo:VO_0011099 a rdfs:Class ;
  rdfs:label "UL27 from Herpes simplex virus type 1" ;
  rdfs:comment "Study demonstrated that recombinant Listeria monocytogenes (Lm) expressing the H-2K(b) glycoprotein B (gB, UL27)(498-505) peptide from HSV-1 triggers a robust CD8 T cell response to this Ag resulting in protective immunity to HSV infection in mice [PubMed: 17404252]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010834 .

obo:VO_0017911 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injectable Solution [Enzira]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017818 .

obo:VO_0003879 a rdfs:Class ;
  rdfs:label "Flublok 2013-2014 Formula Injectable Product" ;
  rdfs:subClassOf obo:VO_0003878 .

obo:VO_0020861 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Csl]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020892 .

obo:VO_0004881 a rdfs:Class ;
  rdfs:label "Adenovirus Type 7 Vaccine Live 32000 UNT" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003176 .

obo:VO_0019916 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:PATO_0001422 a rdfs:Class ;
  rdfs:label "dead" ;
  rdfs:comment "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life." ;
  rdfs:subClassOf obo:PATO_0000169 .

obo:VO_0000103 a rdfs:Class ;
  rdfs:label "TICE BCG" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000367 , obo:VO_0007656 .

obo:VO_0017028 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension [T-Immun Immuno] Box of 10 by Baxter" ;
  rdfs:subClassOf obo:VO_0017027 .

obo:VO_0000704 a rdfs:Class ;
  rdfs:label "antibiotics vaccine residual" ;
  rdfs:comment "a vaccine residual that is from antibiotics used during the manufacture process." ;
  rdfs:subClassOf obo:VO_0000854 .

obo:VO_0000458 a rdfs:Class ;
  rdfs:label "E. coli LB-T vaccine" ;
  rdfs:subClassOf obo:VO_0000041 .

obo:VO_0002434 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Vaccine" ;
  rdfs:subClassOf obo:VO_0002432 , obo:VO_0002433 .

obo:VO_0003694 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2015-2016 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003693 .

obo:NCBITaxon_11723 a rdfs:Class ;
  rdfs:label "Simian immunodeficiency virus" ;
  rdfs:subClassOf obo:NCBITaxon_11646 .

obo:VO_0016980 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.08 MG/ML Injection [ActHIB]" ;
  rdfs:subClassOf obo:VO_0010436 , obo:VO_0016979 , obo:VO_0017444 .

obo:VO_0007475 a rdfs:Class ;
  rdfs:label "fowlpox virus vector vaccine" ;
  rdfs:comment "A recombinant fowlpox virus-based vaccine vector designed to express various tumor-associated peptide antigens. Strong CD8 cytotoxic T cell responses may be induced after prolonged immunization with fowlpox virus vaccines and have been associated with tumor regression. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0018050 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 17500 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018139 .

obo:VO_0000414 a rdfs:Class ;
  rdfs:label "Panvax vaccine" ;
  rdfs:comment "Panvax is an H1N1 unadjuvanted monovalent vaccine." ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003495 .

obo:VO_0000822 a rdfs:Class ;
  rdfs:label "Gag-VRPs vaccine" ;
  rdfs:comment "A cocktail vaccine of V3014-packaged VRPs expressing the SIVsm H-4i nonmyristylated matrix-capsid region, full-length gp160, and a secreted form of gp160 (gp140). PMID:12120997." ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0001935 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4439.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002355 .

obo:VO_0015570 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax]" ;
  rdfs:subClassOf obo:VO_0015491 , obo:VO_0015548 .

obo:VO_0018723 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0018720 .

obo:VO_0005047 a rdfs:Class ;
  rdfs:label "pRc/CMV-HBs(S) DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pRc/CMV-HBs(S).  This plasmid is 5618 base pairs in length and contains a CMV promoter and ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007396 a rdfs:Class ;
  rdfs:label "HER2-pulsed Autologous Type-1 Polarized Dendritic Cell Vaccine" ;
  rdfs:comment "A dendritic cell (DC)-based cancer vaccine composed of autologous, type-1 polarized dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted HER-2-derived peptides, with potential immunomodulatory and antineoplastic activities. Autologous DCs were treated with GM-CSF, interleukin-4, interferon-gamma and bacterial lipopolysaccharide (LPS), a toll-like receptor type 4 agonist, to produce highly polarized DCs (alphaDC1) that are capable of producing high levels of interleukin-12p70 (IL-12p70). Upon administration, HER2-pulsed autologous DC vaccine may stimulate a potent cytotoxic T-lymphocyte (CTL) response against HER-2-positive tumor cells, which may result in tumor cell death and decreased tumor growth. HER-2, a tyrosine kinase receptor for epidermal growth factor (EGF) (also known as neu and ErbB2), is overexpressed by a variety of cancers." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 .

obo:NCBITaxon_2497569 a rdfs:Class ;
  rdfs:label "Negarnaviricota" ;
  rdfs:subClassOf obo:NCBITaxon_2732396 .

obo:VO_0017041 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 20 by Novartis" ;
  rdfs:subClassOf obo:VO_0017040 .

obo:VO_0004435 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine pN4a-MAGE-1-GM" ;
  rdfs:comment "Gene name: GM-CSF" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0018610 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 807000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004822 .

obo:VO_0007492 a rdfs:Class ;
  rdfs:label "gp100:209-217 Peptide vaccine" ;
  rdfs:comment "A synthetic peptide vaccine consisting of amino acids 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen with an endoplasmic reticulum signal sequence (ES) to increase binding activity. Vaccination with gp100:ES209-217(210M) may stimulate the host immune system to mount a cytotoxic T lymphocyte response against tumor cells positive for gp100, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0019717 a rdfs:Class ;
  rdfs:label "influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML [Fluad Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020312 .

obo:VO_0016096 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015992 .

obo:VO_0001447 a rdfs:Class ;
  rdfs:label "VEE Virus gene" ;
  rdfs:comment "A viral gene that is from VEE Virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0020309 a rdfs:Class ;
  rdfs:label "Fluad 2019-2020 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0004281 , obo:VO_0010420 .

obo:VO_0019372 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine wistar strain PM-1503-3M (human), inactivated 2.5 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0020178 .

obo:VO_0002747 a rdfs:Class ;
  rdfs:label "PE2 from VEE Virus" ;
  rdfs:comment "A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001447 .

obo:VO_0000651 a rdfs:Class ;
  rdfs:label "Smallpox virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Smallpox virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003539 .

obo:VO_0016991 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 20 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016990 .

obo:VO_0016932 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 2 LFU/ML / tetanus toxoid vaccine, inactivated 2 LFU/ML Injection by Massbiologics" ;
  rdfs:subClassOf obo:VO_0016929 .

obo:VO_0010213 a rdfs:Class ;
  rdfs:label "human rabies vaccine from Chicken fibroblast culture" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010448 .

obo:VO_0020526 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC] Box of 10" ;
  rdfs:subClassOf obo:VO_0020525 , obo:VO_0020529 , obo:VO_0020873 .

obo:VO_0004183 a rdfs:Class ;
  rdfs:label "Salmonella typhi GroEL protein vaccine" ;
  rdfs:subClassOf obo:VO_0000671 .

obo:VO_0010268 a rdfs:Class ;
  rdfs:label "host comorbidity datum" ;
  rdfs:comment "A measurment datum that records the quality of the host to have a comorbidity." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0017501 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:VO_0005103 a rdfs:Class ;
  rdfs:label "Salmonella-CTLA4-S SARS DNA vaccine" ;
  rdfs:comment "A SARS DNA vaccine that is made from oral live-attenuated auxotrophic S. typhimurium aroA strain SL7207 that contained CTLA4HingeSARS800 with SARS-CoV S protein." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012183 .

obo:VO_0000770 a rdfs:Class ;
  rdfs:label "Staphylococcal vaccine" ;
  rdfs:comment "Vaccine that protects against Staphylococcus infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003555 .

obo:DOID_3292 a rdfs:Class ;
  rdfs:label "mpox"@en ;
  rdfs:comment "A viral infectious disease that results in infection of primates, rodents and humans, located in skin, has_material_basis_in Monkeypox virus (Orthopoxvirus monkeypox), which is transmitted by contact with the animal's blood, body fluids, rash, or with the body fluids of a sick person, transmitted by fomites, and transmitted by respiratory droplets. The infection has symptom fever, has symptom muscle ache, has symptom headache, and has symptom lymphadenopathy."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0019657 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020343 .

obo:VO_0001231 a rdfs:Class ;
  rdfs:label "Leishmania major vaccine" ;
  rdfs:comment "A vaccine that protects against Leishmania major." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000762 .

obo:VO_0010033 a rdfs:Class ;
  rdfs:label "Neospora caninum SRS2" ;
  rdfs:comment "A SRS2 protein that is part of Neospora caninum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0007085 a rdfs:Class ;
  rdfs:label "Recombinant DNA-L523S Vaccine" ;
  rdfs:comment "A plasmid DNA encoding human L523S, an RNA-binding protein that belongs to the KOC (K homology domain containing protein overexpressed in cancer) family, with potential antineoplastic activity. Vaccination with L523S DNA may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells that express the L523S protein. As an oncofetal protein, L523S is normally expressed in early embryonic tissue, but is overexpressed in certain cancer cell types." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0015338 a rdfs:Class ;
  rdfs:label "Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML [Vivaxim]" ;
  rdfs:subClassOf obo:VO_0010748 , obo:VO_0015337 .

obo:VO_0019646 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0020303 .

obo:VO_0011190 a rdfs:Class ;
  rdfs:label "PsaA" ;
  rdfs:comment "Vaccination with an RASV synthesizing full-length PsaA induced high titers of anti-PsaA antibodies in both systemic (IgG in serum) and mucosal (IgA in vaginal washes, nasal washes, and lung homogenates) sites. BALB/c (haplotype H2(d)) or C57BL/6 (haplotype H2(b)) mice vaccinated either orally or intranasally exhibited a significant reduction in colonization of nasopharyngeal tissues after intranasal challenge with S. pneumoniae strains compared to controls, although protection was not observed with all challenge strains. None of the vaccine constructs provided protection against intraperitoneal challenge with S. pneumoniae strain WU2 (serotype 3) [PubMed: 20479086]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0016036 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0003422 .

obo:NCBITaxon_12455 a rdfs:Class ;
  rdfs:label "Borna disease virus" ;
  rdfs:subClassOf obo:NCBITaxon_11157 .

obo:VO_0005468 a rdfs:Class ;
  rdfs:label "tetanus and diphtheria toxoids, not adsorbed, for adult use" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0007435 a rdfs:Class ;
  rdfs:label "EF-2 peptide vaccine" ;
  rdfs:comment "A synthetic peptide derived from the protein ESW/FLI1 type 2 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-2 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FL1 type 2 fusion protein. (NCIT_C49064)." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0018604 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 772000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004824 .

obo:VO_0007052 a rdfs:Class ;
  rdfs:label "URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine" ;
  rdfs:comment "A cancer vaccine containing five peptide epitopes with potential immunostimulatory and antitumor activity. Peptide epitopes in this vaccine are derived from: URLC10 (up-regulated lung cancer 10), TTK (TTK protein kinase), KOC1 (IGF II mRNA Binding Protein 3) and VEGFRs (vascular endothelial growth factor receptors) 1 and 2. Upon administration, URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, TTK, KCO1, VEGFR 1 and 2 peptides, resulting in cell lysis and decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005496 , obo:VO_0007657 .

obo:VO_0018244 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 25000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0020649 a rdfs:Class ;
  rdfs:label "1 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution [Varilrix] Box of 1 by European" ;
  rdfs:subClassOf obo:VO_0020648 .

obo:VO_0003381 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003371 .

obo:VO_0015323 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 , obo:VO_0010451 , obo:VO_0015322 .

obo:VO_0017658 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0007356 a rdfs:Class ;
  rdfs:label "CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine" ;
  rdfs:comment "A plasmid DNA vaccine containing the mammalian expression vector pUMVC3 (pNGVL3) encoding epitopes of CD105 (Endoglin), Y-box binding protein 1 (Yb-1), SRY-box 2 (SOX2), cadherin 3 (CDH3), and murine double minute 2 (MDM2) proteins, with potential immunomodulating and antineoplastic activities. Upon intradermal administration of pUMVC3-CD105/Yb-1/SOX2/CDH3/MDM2-epitopes plasmid DNA vaccine, the plasmid transfects cells and the peptides are expressed. This generates a specific memory Th1 (T-helper) cell immune response, stimulates secretion of cytokines by the T cells and leads to a cytotoxic T-lymphocyte (CTL) response against CD105/Yb-1/SOX2/CDH3/MDM2-expressing tumor cells. CD105/Yb-1/SOX2/CDH3/MDM2 proteins are highly immunogenic tumor associated antigens that are overexpressed in breast cancer. Additionally, these antigens are associated with breast cancer stem cells and with epithelial to mesenchymal transformation (EMT)." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0005035 a rdfs:Class ;
  rdfs:label "pcTPA DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pcTPA.  This plasmid is based on pcDNA3 and contains the hTPA signal sequence." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016367 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Europharma" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0005194 a rdfs:Class ;
  rdfs:label "COVAC vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine with the S1 component of the SARS-CoV-2 spike (S) protein and SWE adjuvant." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0016016 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0003425 .

obo:VO_0001232 a rdfs:Class ;
  rdfs:label "protective antigen" ;
  rdfs:subClassOf obo:OBI_1110034 .

obo:VO_0015163 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0020622 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0020617 .

obo:VO_0017089 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] Box of 10" ;
  rdfs:subClassOf obo:VO_0017088 , obo:VO_0017114 , obo:VO_0017564 .

obo:VO_0005271 a rdfs:Class ;
  rdfs:label "2B182C vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:OPL_0000059 a rdfs:Class ;
  rdfs:label "hepatic schizont stage" ;
  rdfs:comment "A schizont stage that occurs in hepatocyte where sporozoites mature into a schizont." ;
  rdfs:subClassOf obo:OPL_0000084 .

obo:VO_0020409 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI]" .

obo:VO_0004812 a rdfs:Class ;
  rdfs:label "C-KCE (vBAC-C-KCE) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0019836 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0016426 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 3 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015972 .

obo:VO_0007320 a rdfs:Class ;
  rdfs:label "autologous tumor-associated peptide antigen-pulsed dendritic cell vaccine" ;
  rdfs:comment "A dendritic cell (DC)-based cancer vaccine composed of autologous DCs pulsed with specific tumor-associated peptide antigens (TAPA), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous TAPA-pulsed DC vaccine exposes the immune system to the specific TAPAs, which may result in cytotoxic T-lymphocyte (CTL)-mediated immune responses against the TAPA-expressing cancer cells. This leads to cancer cell lysis. This vaccine is specific towards peptides derived from the following proteins: sperm autoantigenic protein 17 (SP17), ropporin, A-kinase anchor protein 4 (AKAP4), pituitary tumor-transforming 1 (PTTG1) and SPANX family member B (SPANX-B)." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0019223 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0019476 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.015 MG/ML / Neisseria meningitidis 0.25 MG/ML Injectable Suspension [Liquid PedvaxHIB]" ;
  rdfs:subClassOf obo:VO_0019475 .

obo:VO_0017248 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017246 .

obo:VO_0017421 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Adt Booster]" ;
  rdfs:subClassOf obo:VO_0017383 , obo:VO_0017420 .

obo:VO_0004470 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine D1ME encoding prM and E" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0001309 a rdfs:Class ;
  rdfs:label "protein cochleates vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant synthesized from stable protein phospholipid-calcium precipitates." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0002028 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 12A5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0002486 .

obo:VO_0015009 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML [ActHIB]" ;
  rdfs:subClassOf obo:VO_0001214 , obo:VO_0015011 .

obo:VO_0017531 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 250 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0005154 a rdfs:Class ;
  rdfs:label "SARS-CoV pCI-N DNA vaccine" ;
  rdfs:comment "A plasmid pCI-N, encoding the full-length N gene of SARS-CoV, was constructed and expressed in Escherichia coli DH5alpha" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012183 .

obo:VO_0002474 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus Vaccine-Escherichia Coli Bacterin" ;
  rdfs:subClassOf obo:VO_0000041 , obo:VO_0000563 , obo:VO_0001474 , obo:VO_0001495 .

obo:VO_0003029 a rdfs:Class ;
  rdfs:label "gelatin vaccine stabilizer" ;
  rdfs:comment "a vaccine stabilizer that is gelatin." ;
  rdfs:subClassOf obo:VO_0000853 .

obo:VO_0001595 a rdfs:Class ;
  rdfs:label "avian influenza H6N8 Subtype, Killed Virus Vaccine (USDA: 1057.H6)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0004339 a rdfs:Class ;
  rdfs:label "VHSV DNA vaccine pCMV-vhsN encoding nucleocapsid protein N and glycoprotein G" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001224 .

obo:VO_0003657 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003655 .

obo:VO_0015297 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015292 .

obo:VO_0021048 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Prefilled Syringe [Zostavax]" ;
  rdfs:subClassOf obo:VO_0000124 , obo:VO_0021047 .

obo:VO_0011138 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Viet Nam/1203/2004(H5N1))" ;
  rdfs:comment "Researchers evaluated the immunogenicity and efficacy of a panel of flagellin-based hemagglutinin (HA) globular head fusion vaccines in inbred mice. The HA globular head of these vaccines was derived from the A/Vietnam/1203/04 (VN04; H5N1) HA molecule. Results show that replacement of domain D3 of flagellin with the VN04 HA globular head creates a highly effective vaccine that elicits protective HAI titers which protect mice against disease and death in a lethal challenge model with H5 VN virus [PubMed: 19654064]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0019357 a rdfs:Class ;
  rdfs:label "0.7 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.0857 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0000403 a rdfs:Class ;
  rdfs:label "porin-S-LPS from Brucella abortus strain 2308 vaccine" ;
  rdfs:subClassOf obo:VO_0001221 .

obo:VO_0007204 a rdfs:Class ;
  rdfs:label "Adenovirus Encoding Rat HER-2/neu Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a recombinant adenoviral vector encoding HER-2/neu." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0003970 a rdfs:Class ;
  rdfs:label "Pentacel Injectable Product" ;
  rdfs:subClassOf obo:VO_0000084 .

obo:VO_0017100 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017099 .

obo:VO_0010129 a rdfs:Class ;
  rdfs:label "host disease state variable" ;
  rdfs:comment "A variable representing the host's participation in a disease state (i.e. healthy, or diabetic)." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0020821 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Adacel]" ;
  rdfs:subClassOf obo:VO_0000005 .

obo:VO_0002428 a rdfs:Class ;
  rdfs:label "equine EEV and WEV encephalomyelitis-rhinopneumonitis vaccine-tetanus toxoid" ;
  rdfs:subClassOf obo:VO_0001486 , obo:VO_0002420 .

obo:VO_0015258 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Havpur] Box of 10" ;
  rdfs:subClassOf obo:VO_0015256 , obo:VO_0015260 .

obo:VO_0004686 a rdfs:Class ;
  rdfs:label "BoHV-4-A-IgK-VP2gD vaccine" ;
  rdfs:subClassOf obo:VO_0001466 , obo:VO_0001515 .

obo:VO_0017268 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.025 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Covaxis]" ;
  rdfs:subClassOf obo:VO_0018773 .

obo:VO_0020432 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Sanofi" .

obo:VO_0001455 a rdfs:Class ;
  rdfs:label "rinderpest virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Rinderpest virus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003543 .

obo:VO_0003903 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003067 , obo:VO_0010431 .

obo:VO_0016584 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016577 .

obo:VO_0005075 a rdfs:Class ;
  rdfs:label "VR1055 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label VR1055.  This plasmid is derived from pUC19 and contains a CMV promoter, kanamycin resistance gene, a cloning polylinker, and a transcriptional terminator region derived from the rabbit beta-globin gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000021 a rdfs:Class ;
  rdfs:label "Brucella abortus vaccine RB51" ;
  rdfs:comment "Brucella abortus vaccine RB51 is a Brucella abortus vaccine that is licensed in the USA since 1992." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000643 , obo:VO_0001134 .

obo:VO_0016990 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0016987 , obo:VO_0017478 .

obo:OBI_0000383 a rdfs:Class ;
  rdfs:label "transfer function"@en ;
  rdfs:comment "A transfer function is a function to displace a material from one location to another."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:VO_0016736 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0016707 , obo:VO_0016768 .

obo:VO_0011257 a rdfs:Class ;
  rdfs:label "VP6 from Rotavirus A" ;
  rdfs:comment "VP6 derived from Group A rotavirus conferred in vivo partial protection against rotavirus challenge in a neonatal mouse model [PubMed: 18632867]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010789 .

obo:VO_0003577 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 40000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 20000 UNT/ML [ProQuad]" ;
  rdfs:subClassOf obo:VO_0000091 .

obo:VO_0010191 a rdfs:Class ;
  rdfs:label "influenza, Southern Hemisphere, unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0007266 a rdfs:Class ;
  rdfs:label "anti-NY-ESO-1 Immunotherapeutic GSK-2241658A vaccine" ;
  rdfs:comment "An immunotherapeutic agent targeting the tumor-associated antigen (TAA), cancer/testis antigen NY-ESO-1, with potential antineoplastic activity." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0018377 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003346 .

obo:VO_0015071 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML" ;
  rdfs:subClassOf obo:VO_0015069 .

obo:VO_0020489 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2019-2020 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010420 .

obo:VO_0020980 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, Inactivated, Strain B / Phuket / 3073/2013 & ndash; Analogue strain B / Utah / 9/2014, Wild Type" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0010305 , obo:VO_0010415 .

obo:VO_0000098 a rdfs:Class ;
  rdfs:label "SIV based lentivirus vaccine vector" ;
  rdfs:comment "a lentivirus vaccine vector that uses a SIV strain as the vector" ;
  rdfs:subClassOf obo:VO_0000359 .

obo:VO_0015266 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0015233 , obo:VO_0015264 , obo:VO_0015265 .

obo:VO_0015506 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0003423 .

obo:VO_0017050 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac]" ;
  rdfs:subClassOf obo:VO_0017049 , obo:VO_0017522 .

obo:VO_0000215 a rdfs:Class ;
  rdfs:label "pCMV DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003880 a rdfs:Class ;
  rdfs:label "Flublok 2013-2014 Formula Influenza Virus Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003879 .

obo:VO_0004374 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine encoding TSA-1, ASP-1, ASP-2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0017484 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [T Immun]" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:VO_0015483 a rdfs:Class ;
  rdfs:label "Giardia lamblia protein" ;
  rdfs:subClassOf obo:VO_0010829 .

obo:VO_0001465 a rdfs:Class ;
  rdfs:label "cat vaccine" ;
  rdfs:comment "Vaccine that used for immunizing cat (felis catus)." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001464 .

obo:VO_0002168 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1775.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0018114 a rdfs:Class ;
  rdfs:label "1 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0018109 , obo:VO_0018178 .

obo:DOID_10155 a rdfs:Class ;
  rdfs:label "intestinal cancer"@en ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the intestine."@en ;
  rdfs:subClassOf obo:DOID_3119 , obo:DOID_5295 .

obo:VO_0016212 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0005255 a rdfs:Class ;
  rdfs:label "ABNCoV2 vaccine" ;
  rdfs:comment "A COVID-19 virus-like particle vaccine developed by Radboud University" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005205 .

obo:VO_0010837 a rdfs:Class ;
  rdfs:label "Leishmania amazonensis protein" ;
  rdfs:subClassOf obo:VO_0015478 .

obo:VO_0002170 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Mass & Ark Types, Killed Virus Vaccine (USDA: 1785.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0007625 a rdfs:Class ;
  rdfs:label "intralesional bacile Calmette-Guerin (BCG), DTIC, vincristine vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0018803 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 .

obo:NCBITaxon_10141 a rdfs:Class ;
  rdfs:label "Cavia porcellus" ;
  rdfs:subClassOf obo:NCBITaxon_33550 .

obo:VO_0000375 a rdfs:Class ;
  rdfs:label "live attenuated vaccine preparation by gene mutant" ;
  rdfs:comment "A live attenuated vaccine prepraration process that is performed by mutation of a gene(s) from a virulent pathogen." ;
  rdfs:subClassOf obo:VO_0000718 .

obo:VO_0002328 a rdfs:Class ;
  rdfs:label "avian encephalomyelitis-fowl pox-Mycoplasma gallisepticum vaccine" ;
  rdfs:subClassOf obo:VO_0002326 , obo:VO_0002445 .

obo:VO_0011274 a rdfs:Class ;
  rdfs:label "LmSTI1" ;
  rdfs:comment "Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge with L. major. Mice inoculated pCMV3ISS-LmSTI1 developed significantly smaller lesions in their footpads after challenge with the parasite. The vaccine was able to induce a partially protective effect [PubMed: 18951941]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:OBI_0000751 a rdfs:Class ;
  rdfs:label "study design dependent variable"@en ;
  rdfs:comment "dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies."@en ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0007579 a rdfs:Class ;
  rdfs:label "obsolete Autologous Immunoglobulin Idiotype-KLH Conjugate Vaccine" .

obo:VO_0004915 a rdfs:Class ;
  rdfs:label "vaccine specific interferon-γ immune response" ;
  rdfs:comment "vaccine-induced T-helper 1 type immune response that is indicated by the presence of Interferon-gamma production" ;
  rdfs:subClassOf obo:VO_0000100 .

obo:NCBITaxon_11646 a rdfs:Class ;
  rdfs:label "Lentivirus" ;
  rdfs:subClassOf obo:NCBITaxon_327045 .

obo:VO_0006030 a rdfs:Class ;
  rdfs:label "meningococcal AC polysaccharide vaccine (non-US)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0005028 a rdfs:Class ;
  rdfs:label "pCI30 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCI30.  This plasmid contains a CMV promoter, ampicillin resistance gene, T7 RNA polymerase promoter, a multiple cloning region and a 6xHis tag coding sequence." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:NCBITaxon_9901 a rdfs:Class ;
  rdfs:label "Bison bison" ;
  rdfs:subClassOf obo:NCBITaxon_9900 .

obo:VO_0016275 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015924 .

obo:VO_0007008 a rdfs:Class ;
  rdfs:label "VEGFR-2 DNA Vaccine VXM01" ;
  rdfs:comment "An orally available DNA cancer vaccine containing an attenuated strain of the bacterium Salmonella typhimurium encoding murine vascular endothelial growth factor receptor 2 (VEGFR-2) (VXM01), with potential immunomodulating, anti-angiogenic and antineoplastic activity. Upon oral administration and successful transduction, VEGFR-2 DNA vaccine VXM01 expresses VEGFR-2 in addition to inducing the expression of T-cell activation markers, such as CD25, interleukin-2, the early T-cell activation antigen CD69 and the lymphocyte function-associated antigen LFA-2. The immune response targets the fast growing VEGFR-2 expressing endothelial cells found in the tumor vasculature, thereby blocking angiogenesis which may ultimately inhibit tumor cell proliferation. VEGFR-2 is a receptor tyrosine kinase overexpressed on proliferating endothelial cells in the tumor vasculature." ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 , obo:VO_0007660 .

obo:DOID_1116 a rdfs:Class ;
  rdfs:label "pertussis"@en ;
  rdfs:comment "A commensal bacterial infectious disease that results_in inflammation located_in respiratory tract, has_material_basis_in Bordetella pertussis, or has_material_basis_in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by a prolonged, high-pitched, deeply indrawn breath (whoop)."@en ;
  rdfs:subClassOf obo:DOID_104 .

obo:VO_0004295 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pIRES/NA expressing NA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0017981 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML Prefilled Syringe [ActHIB] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017964 .

obo:VO_0019117 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0020303 .

obo:VO_0000027 a rdfs:Class ;
  rdfs:label "pAp031 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0012169 a rdfs:Class ;
  rdfs:label "Nipah virus vaccine" ;
  rdfs:comment "A vaccine that protects against Nipah virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0011161 a rdfs:Class ;
  rdfs:label "NH" ;
  rdfs:comment "Experimental infection of immunized BALB/c mice demonstrated that the VR1012-NH36 DNA vaccine derived from the nucleoside hydrolase gene (NH) of L. donovani induced an 88% reduction in L. chagasi parasite load and a 65% reduction in L. mexicana lesion size [PubMed: 15664920]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0015073 a rdfs:Class ;
  rdfs:label "injectable solution" ;
  rdfs:subClassOf obo:VO_0015062 .

obo:VO_0003683 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Fluvirin 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003681 .

obo:DOID_10534 a rdfs:Class ;
  rdfs:label "stomach cancer"@en ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the stomach."@en ;
  rdfs:subClassOf obo:DOID_3119 .

obo:VO_0001949 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1185.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0002358 .

obo:VO_0003485 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010304 , obo:VO_0010415 .

obo:NCBITaxon_622 a rdfs:Class ;
  rdfs:label "Shigella dysenteriae" ;
  rdfs:subClassOf obo:NCBITaxon_620 .

obo:VO_0001269 a rdfs:Class ;
  rdfs:label "Montanide incomplete Seppic adjuvant" ;
  rdfs:comment "A Montanide vaccine adjuvant that is a mineral oil adjuvant." ;
  rdfs:subClassOf obo:VO_0001271 .

obo:VO_0016760 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 150 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016695 .

obo:VO_0003501 a rdfs:Class ;
  rdfs:label "human influenza A (H3N2) virus vaccine" ;
  rdfs:subClassOf obo:VO_0003495 .

obo:VO_0019191 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2020 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020490 .

obo:VO_0004257 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum PmpG-1, PmpE/F-2, and MOMP protein vaccine" ;
  rdfs:subClassOf obo:VO_0012176 .

obo:VO_0003900 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Flublok Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003898 .

obo:VO_0001645 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.17)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0002532 a rdfs:Class ;
  rdfs:label "leuD from Mycobacterium tuberculosis" ;
  rdfs:comment "Deletion of leuD gene was shown to be highly attenuated. Immunocompetent BALB/c mice vaccinated with the DleuD auxotroph were protected as well as BCG in terms of survival following an intravenous or aerosol challenge with virulent M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0007586 a rdfs:Class ;
  rdfs:label "BCG and chemotherapy for malignant melanoma vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0000342 a rdfs:Class ;
  rdfs:label "intranasal route by drop" ;
  rdfs:subClassOf obo:VO_0000341 .

obo:DOID_1993 a rdfs:Class ;
  rdfs:label "rectum cancer"@en ;
  rdfs:comment "A colorectal cancer that is located_in the rectum."@en ;
  rdfs:subClassOf obo:DOID_9256 .

obo:VO_0005143 a rdfs:Class ;
  rdfs:label "LNP-nCoVsaRNA vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine made of self-coding RNA encoding SARS-CoV-2 spike protein encapsulated within a lipid nanoparticle." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0019419 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.069 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.0016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.0032 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.0064 MG/ML / diphtheria toxoid vaccine, inactivated 18 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017799 .

obo:VO_0020749 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020747 , obo:VO_0020755 .

obo:NCBITaxon_5500 a rdfs:Class ;
  rdfs:label "Coccidioides" ;
  rdfs:subClassOf obo:NCBITaxon_4751 .

obo:VO_0020078 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.12 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0010227 a rdfs:Class ;
  rdfs:label "yellow fever vaccine live - alternative formulation for vaccine shortage" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010456 .

obo:OPL_0000251 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum trophozoite stage" ;
  rdfs:comment "A trophozoite stage in the Plasmodium falciparum lifecycle that occurs in a human host." ;
  rdfs:subClassOf obo:OPL_0000057 , obo:OPL_0000165 , obo:OPL_0000303 .

obo:IAO_8000013 a rdfs:Class ;
  rdfs:label "reasoned ontology module"@en ;
  rdfs:comment "An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/reason> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OPL_0000296 a rdfs:Class ;
  rdfs:label "Plasmodium ookinete stage" ;
  rdfs:comment "An ookinete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector and on the outside of the midgut." ;
  rdfs:subClassOf obo:OPL_0000153 .

obo:VO_0020868 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Inflexal] Box of 10" ;
  rdfs:subClassOf obo:VO_0020867 , obo:VO_0020884 .

obo:VO_0011115 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Aichi/2/1968(H3N2)), (X31)" ;
  rdfs:comment "Two cyclic peptide analogues corresponding to residues 139-146 (site A) of influenza A virus haemagglutinin (strain X31) were synthesized.  When OF1 mice were immunized with cyclic peptides, approximately 80% of the animals were protected against an intranasal challenge with influenza virus [PubMed: 2396470]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0019608 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluad Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020311 .

obo:NCBITaxon_90370 a rdfs:Class ;
  rdfs:label "Salmonella enterica subsp. enterica serovar Typhi" ;
  rdfs:subClassOf obo:NCBITaxon_59201 .

obo:VO_0016269 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015923 .

obo:VO_0000382 a rdfs:Class ;
  rdfs:label "pharyngeal mucosal vaccination" ;
  rdfs:subClassOf obo:VO_0003021 .

obo:VO_0003392 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 96 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003196 .

obo:VO_0016872 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Infanrix] Box of 25 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016812 .

obo:VO_0017256 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Covaxis]" ;
  rdfs:subClassOf obo:VO_0017808 , obo:VO_0018769 .

obo:VO_0002066 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease Killed Virus Vaccine (USDA: 12G5.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002365 , obo:VO_0007748 .

obo:VO_0003641 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Fluzone Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003638 .

obo:VO_0020638 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe [Zostavax] Box of 1" ;
  rdfs:subClassOf obo:VO_0020637 , obo:VO_0021030 .

obo:VO_0010141 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, tris-sucrose, 10 mcg/0.3 mL dose" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000455 , obo:VO_0005268 .

obo:VO_0001221 a rdfs:Class ;
  rdfs:label "Brucella abortus subunit vaccine" ;
  rdfs:comment "a B. abortus vaccine that uses subunit antigen" ;
  rdfs:subClassOf obo:VO_0000108 , obo:VO_0000534 .

obo:VO_0019172 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.265 MG/ML / hepatitis B surface antigen vaccine 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0019485 .

obo:VO_0015100 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Havpur] Box of 1" ;
  rdfs:subClassOf obo:VO_0015099 , obo:VO_0015103 , obo:VO_0015257 .

obo:VO_0002518 a rdfs:Class ;
  rdfs:label "apxIIA from Actinobacillus pleuropneumoniae" ;
  rdfs:comment "Deletion in ureC and apxIIA genes of Actinobacillus pleuropneumoniae serotype 2 prototype provides attenuation and protection in pigs against challenge with the virulent parent strain of A. pleuropneumoniae" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001384 .

obo:VO_0007041 a rdfs:Class ;
  rdfs:label "recombinant Vaccinia-NY-ESO-1 vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant vaccinia viral vector encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1, an antigen found in normal testis and various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. Vaccination with recombinant vaccinia- NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0002153 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1761.17)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0004523 a rdfs:Class ;
  rdfs:label "Herpes Simplex Virus 2 DNA Vaccine encoding gD with CD40L" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0018440 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 20" ;
  rdfs:subClassOf obo:VO_0018422 .

obo:VO_0018753 a rdfs:Class ;
  rdfs:label "Tick-borne encephalitis virus inactivated" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000712 , obo:VO_0000952 .

obo:VO_0011053 a rdfs:Class ;
  rdfs:label "CDVgp5" ;
  rdfs:comment "Study reports the engineering and the characterization of two replication-competent canine adenovirus type 2 (CAV2)-based vaccines expressing, respectively, the CDV hemagglutinin (HA) and fusion (F) antigens (CDVgp5). We first demonstrated that the intranasal vaccination with a mixture of both recombinant CAV2s provides an excellent level of protection in seronegative puppies, confirming the value of replication-competent adenovirus-based vectors for mucosal vaccination [PubMed: 12297394]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010809 .

obo:VO_0000953 a rdfs:Class ;
  rdfs:label "pharyngeal mucosal route" ;
  rdfs:comment "Pharyngeal mucosal route is an oral route of administration." ;
  rdfs:subClassOf obo:VO_0000886 .

obo:VO_0010189 a rdfs:Class ;
  rdfs:label "influenza, Madin Darby Canine Kidney, subunit, quadrivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000534 , obo:VO_0010415 .

obo:VO_0003269 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 12F vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003218 .

obo:VO_0020001 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML Prefilled Syringe [Fluzone Intradermal 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019998 .

obo:VO_0001679 a rdfs:Class ;
  rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000985 , obo:VO_0001220 , obo:VO_0007748 .

obo:OBI_0000237 a rdfs:Class ;
  rdfs:label "antigen role"@en ;
  rdfs:comment "A role of a material entity that is being recognized in whole or in part by receptors of the immune system such as antibodies or T cell receptors."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0000902 a rdfs:Class ;
  rdfs:label "PROTEQ-FLU vaccine (European Union)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0003143 .

obo:VO_0020320 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2019-2020 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0000983 , obo:VO_0010420 .

obo:VO_0004363 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis DNA vaccine (containing the ESAT-6, MPT-64, MPT-83, and KatG constructs)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:NCBITaxon_11034 a rdfs:Class ;
  rdfs:label "Sindbis virus" ;
  rdfs:subClassOf obo:NCBITaxon_11019 .

obo:VO_0016197 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015902 .

obo:NCBITaxon_9850 a rdfs:Class ;
  rdfs:label "Cervidae" ;
  rdfs:subClassOf obo:NCBITaxon_35500 .

obo:VO_0000559 a rdfs:Class ;
  rdfs:label "adamantylamide dipeptide vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant, adamantylamide dipeptide (AdDP) is the desmuramyl analog of MDP." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:DOID_1319 a rdfs:Class ;
  rdfs:label "brain cancer"@en ;
  rdfs:comment "A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain."@en ;
  rdfs:subClassOf obo:DOID_3620 .

obo:VO_0006063 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 30 mcg/0.3mL dose tris-sucrose formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0018764 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension [Stamaril] Box of 10" ;
  rdfs:subClassOf obo:VO_0018762 , obo:VO_0018766 .

obo:VO_0002529 a rdfs:Class ;
  rdfs:label "relA from Mycobacterium avium" ;
  rdfs:comment "A M. avium relA mutant is attenuated in calves and goats. This mutant also elicited an immune response in goats that limited colonization by challenge wild type M. avium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001404 .

obo:VO_0018880 a rdfs:Class ;
  rdfs:label "influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010301 , obo:VO_0010415 .

obo:VO_0015743 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 100" ;
  rdfs:subClassOf obo:VO_0015495 , obo:VO_0015808 .

obo:VO_0019271 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010423 .

obo:VO_0017571 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 10" ;
  rdfs:subClassOf obo:VO_0017570 , obo:VO_0017576 .

obo:VO_0016920 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 LFU/ML / Pertussis Vaccine 0.0468 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension [Tripacel]" ;
  rdfs:subClassOf obo:VO_0016919 , obo:VO_0017307 .

obo:VO_0018503 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018428 .

obo:VO_0000439 a rdfs:Class ;
  rdfs:label "USDA licensed vaccine role" ;
  rdfs:comment "a USA licensed vaccine role that indicates the vaccine is for veterinary uses." ;
  rdfs:subClassOf obo:VO_0000812 .

obo:VO_0010866 a rdfs:Class ;
  rdfs:label "VP24 from Zaire ebolavirus" ;
  rdfs:comment "VP24 expressed from alphavirus replicons induced a protective immune response in BALB/c mice when challenged with Ebola virus Zaire [PubMed: 11485406]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0007087 a rdfs:Class ;
  rdfs:label "Tergenpumatucel-L Vaccine" ;
  rdfs:comment "An allogeneic lung cancer vaccine with potential immunostimulating and antineoplastic activities. Derived from allogeneic lung tumor cells, tergenpumatucel-L is engineered to express the murine alpha-1,3-galactosyltransferase (GalT), an enzyme humans lack. GalT catalyzes the expression of foreign alpha-1,3-galactosyl (alpha-gal) carbohydrate epitopes in glycoproteins and in glycolipids on the cell membranes of the allogeneic lung tumor cells present in the vaccine, essentially producing a 'xenograft'. The hyperacute rejection involves pre-existing human anti-alpha-gal antibodies that bind the foreign alpha-gal epitopes expressed by the vaccine tumor cell xenograft, resulting in complement-mediated cytotoxicity (CMC) and antibody-dependent cell-mediated cytotoxicity (ADCC) towards endogenous lung tumor cells with unmodified carbohydrate epitopes." ;
  rdfs:subClassOf obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0017241 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Hepatitis B Surface Antigen Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003172 , obo:VO_0017808 .

obo:NCBITaxon_10294 a rdfs:Class ;
  rdfs:label "Simplexvirus" ;
  rdfs:subClassOf obo:NCBITaxon_10293 .

obo:VO_0018353 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003339 .

obo:VO_0016378 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015941 .

obo:VO_0019501 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Injection [Havrix]" ;
  rdfs:subClassOf obo:VO_0003827 , obo:VO_0019500 .

obo:VO_0015517 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML [H-B-Vax II]" ;
  rdfs:subClassOf obo:VO_0003230 .

obo:VO_0001866 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E1.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0001217 , obo:VO_0002437 , obo:VO_0007748 .

obo:VO_0004195 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum CS expressed in irradiated  Plasmodium berghei vaccine" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:NCBITaxon_7898 a rdfs:Class ;
  rdfs:label "Actinopterygii" ;
  rdfs:subClassOf obo:NCBITaxon_117571 .

obo:VO_0019996 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe [Fluzone Intradermal 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020486 .

obo:VO_0007636 a rdfs:Class ;
  rdfs:label "MAGE-A3 + AS15 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0000109 a rdfs:Class ;
  rdfs:label "Tetanus Toxoid Adsorbed by Aventis Pasteur Inc vaccine" ;
  rdfs:comment "Product Name: Tetanus Toxoid Adsorbed" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000714 , obo:VO_0010436 .

obo:VO_0004244 a rdfs:Class ;
  rdfs:label "Inactivated split Mem 71 Virus with SPT adjuvant vaccine" ;
  rdfs:subClassOf obo:VO_0001176 .

obo:UBERON_0004921 a rdfs:Class ;
  rdfs:label "subdivision of digestive tract" ;
  rdfs:comment "A proximal-distal subdivision of the digestive tract." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:VO_0018374 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003333 .

obo:VO_0007295 a rdfs:Class ;
  rdfs:label "Autologous GM-CSF-Secreting Breast Cancer Vaccine" ;
  rdfs:comment "An autologous tumor cell vaccine containing irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Autologous breast cancer cells are transduced ex vivo with an adenovirus vector encoding the GM-CSF gene and irradiated and then reintroduced into the patient. Upon repeated subcutaneous administration of the vaccine, autologous GM-CSF-secreting breast cancer cells secrete GM-CSF, which may stimulate a tumor-specific cytotoxic T-lymphocyte (CTL) response." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0016175 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0015084 a rdfs:Class ;
  rdfs:label "Influenza A virus (H1N1) antigen" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0016827 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0016734 , obo:VO_0016776 .

obo:VO_0017391 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 LFU/ML / tetanus toxoid vaccine, inactivated 2 LFU/ML Injection" ;
  rdfs:subClassOf obo:VO_0017670 .

obo:VO_0019498 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine (inactivated) strain HM175 / typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0010438 , obo:VO_0010451 , obo:VO_0015231 .

obo:VO_0004884 a rdfs:Class ;
  rdfs:label "Menomune A/C/Y/W-135 Vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0004883 .

obo:VO_0015157 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Haematogmbh" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0007255 a rdfs:Class ;
  rdfs:label "Ankara (MVA) and ALVAC(2) vaccine" ;
  rdfs:comment "Recombinant MVA-gp100M and ALVAC(2)-5T4 were constructed to complement existing ALVAC(2)-gp100M and MVA-5T4 vectors. Recombinant TAA expression in chicken embryo fibroblast cells was confirmed by Western blot analysis. 5T4 expression was approximately equal for both viruses, whereas ALVAC-derived gp100 was quickly degraded, at a time point when MVA-derived gp100 was still stable and expressed at high levels" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0020055 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Injectable Suspension [Fluvirin 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020355 .

obo:VO_0016675 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0003429 .

obo:NCBITaxon_393305 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica subsp. enterocolitica 8081" ;
  rdfs:subClassOf obo:NCBITaxon_150052 .

obo:VO_0001560 a rdfs:Class ;
  rdfs:label "Bovine Respiratory Syncytial Virus Vaccine Modified Live Virus (USDA: 1091.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0001507 .

obo:VO_0017070 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Tetamun] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017069 .

obo:VO_0006023 a rdfs:Class ;
  rdfs:label "influenza virus vaccine split virus (incl. purified surface antigen)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0015652 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015571 , obo:VO_0015674 .

obo:VO_0018266 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated Injectable Suspension [Tollwut-Impfstoff]" ;
  rdfs:subClassOf obo:VO_0018274 .

obo:VO_0010184 a rdfs:Class ;
  rdfs:label "influenza, Madin Darby Canine Kidney, subunit, trivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000534 , obo:VO_0010415 .

obo:VO_0019937 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Flulaval Quad 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020341 .

obo:VO_0002106 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0003486 a rdfs:Class ;
  rdfs:label "influenza B virus B/Utah/9/2014 antigen" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:VO_0000968 a rdfs:Class ;
  rdfs:label "pBLUESCRIPT DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pBLUESCRIPT." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003182 a rdfs:Class ;
  rdfs:label "Mumps-Rubella vaccine foreign to USA" ;
  rdfs:comment "A Mumps-Rubella vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0003418 , obo:VO_0003444 .

obo:VO_0010916 a rdfs:Class ;
  rdfs:label "Hap from H. influenzae" ;
  rdfs:comment "When mice immunized intranasally with recombinant protein corresponding to the C-terminal region of Hap(S) from H. influenzae strains N187, P860295, and TN106 plus mutant cholera toxin CT-E29H were challenged with strain TN106, they were protected against nasopharyngeal colonization [PubMed: 15557618]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:OPL_0000084 a rdfs:Class ;
  rdfs:label "schizont stage" ;
  rdfs:comment "A parasite lifecycle stage that is the multinucleate stage in the development of some members of the Sarcodina and some sporozoans during schizogony." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0015274 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0015267 .

obo:VO_0020302 a rdfs:Class ;
  rdfs:label "Afluria 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000006 , obo:VO_0000578 , obo:VO_0010417 .

obo:VO_0001855 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live & Killed Virus Vaccine (USDA: 16D9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0002436 , obo:VO_0007748 .

obo:VO_0002248 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002422 , obo:VO_0003143 , obo:VO_0007748 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:VO_0020720 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 660000000 CFU Injection [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020718 , obo:VO_0020719 , obo:VO_0020741 .

obo:VO_0007442 a rdfs:Class ;
  rdfs:label "HIVgP160 vaccine" ;
  rdfs:comment "A synthetic HIV vaccine based on a recombinant canary pox virus vector expressing the human immunodeficiency virus (HIV) glycoprotein gp160. HIVgP160 vaccine has been used to generate in vivo primary T lymphocyte response against HIV antigens." ;
  rdfs:subClassOf obo:VO_0000295 , obo:VO_0000455 .

obo:VO_0011429 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus DNA vaccine encoding OmlA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001085 .

obo:VO_0017759 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017756 .

obo:VO_0020965 a rdfs:Class ;
  rdfs:label "Influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0003521 .

obo:VO_0007024 a rdfs:Class ;
  rdfs:label "NY-ESO-1 peptide vaccine" ;
  rdfs:comment "A cancer vaccine consisting of an immunogenic peptide derived from the cancer-testis antigen (NY-ESO-1), an antigen found in normal testis and various tumors. Vaccination with NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response to cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005489 , obo:VO_0005493 , obo:VO_0005496 , obo:VO_0007657 .

obo:VO_0010945 a rdfs:Class ;
  rdfs:label "FimH from E. coli UTI89" ;
  rdfs:comment "FimH is a protective antigen [PubMed: 9110982]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0020525 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020524 , obo:VO_0020872 .

obo:VO_0020559 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Csl] Box of 10 by bioCSL" ;
  rdfs:subClassOf obo:VO_0020558 .

obo:VO_0019596 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Nasal Spray [Flumist Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003820 , obo:VO_0019592 .

obo:VO_0003006 a rdfs:Class ;
  rdfs:label "Leishmania infantum HSP70 II mutant vaccine" ;
  rdfs:comment "A Leishmania infantum deletion mutant of HSP70-II gene is attenuated and provides protection against Leishmania infection in the L. major-BALB/c infection model. Also, DeltaHSP70-II is a safe live vaccine as immunodeficient SCID mice, and hamsters, infected with mutant parasites did not develp any sign of pathology" ;
  rdfs:subClassOf obo:VO_0012159 .

obo:VO_0007481 a rdfs:Class ;
  rdfs:label "gp100 + Mart-1 + Mart-3 vaccine" ;
  rdfs:comment "A vaccine that injected peptides of gp100, MART-1, MAGE-3" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0004651 a rdfs:Class ;
  rdfs:label "BV-RVG/RVG vaccine" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0007238 a rdfs:Class ;
  rdfs:label "Alpha-Galactosylceramide-Pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with the marine sponge glycolipid alpha-galactosylceramide (alpha-GalCer) with potential immunostimulatory and antimetastatic activities. Upon administration, alpha-galactosylceramide-pulsed autologous dendritic cells may result in the activation and proliferation of a subset of endogenous natural killer T (NKT) cells, B cells, and CD4+ and CD8+ T cells, and the production of interferon-gamma and interleukin-12; these cascade events may result in a T helper-1 cell-biased proinflammatory antitumor immune response. The NKT cell ligand alpha-GalCer was originally isolated from the marine sponge Agelas mauritianusis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0017284 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Tripacel]" ;
  rdfs:subClassOf obo:VO_0017233 , obo:VO_0017283 .

obo:VO_0018364 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003342 .

obo:VO_0005420 a rdfs:Class ;
  rdfs:label "GLA-SE vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0016686 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Repevax]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0018195 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0000746 a rdfs:Class ;
  rdfs:label "Haemophilus b and Hepatitis B vaccine" ;
  rdfs:comment "a viral vaccine against Hepatitis B virus and at the same time against bacterial H. influenzae serotype b." ;
  rdfs:subClassOf obo:VO_0000644 , obo:VO_0000662 .

obo:VO_0004605 a rdfs:Class ;
  rdfs:label "SL3261 expressing Trichinella spiralis Ag30 vaccine" ;
  rdfs:subClassOf obo:VO_0001074 , obo:VO_0002792 .

obo:VO_0004631 a rdfs:Class ;
  rdfs:label "rAd-GP Ebola virus vaccine" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0000166 a rdfs:Class ;
  rdfs:label "bacterial vaccine vector" ;
  rdfs:comment "a vaccine vector that uses a live bacterium as the vector " ;
  rdfs:subClassOf obo:VO_0000599 .

obo:VO_0004691 a rdfs:Class ;
  rdfs:label "RCN-HA (H5N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0016047 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 100" ;
  rdfs:subClassOf obo:VO_0015670 , obo:VO_0015802 .

obo:VO_0016957 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0016956 , obo:VO_0017418 .

obo:VO_0017349 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017808 .

obo:VO_0020601 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Xanaflu] Box of 10 by Mylan" ;
  rdfs:subClassOf obo:VO_0020600 .

obo:VO_0001540 a rdfs:Class ;
  rdfs:label "Feline calicivirus Killed Virus Vaccine (USDA: 15C5.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001509 , obo:VO_0007748 .

obo:VO_0005006 a rdfs:Class ;
  rdfs:label "pPJV7563 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pPJV7563.  This plasmid has a human cytomegalovirus immediate early promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016106 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 20 by Merck" ;
  rdfs:subClassOf obo:VO_0015994 .

obo:VO_0019867 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0002096 a rdfs:Class ;
  rdfs:label "Canine Distemper-Measles Modified Live Virus Vaccine (USDA: 1351.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002416 , obo:VO_0007748 .

obo:VO_0005295 a rdfs:Class ;
  rdfs:label "CaPNP (CaPtivant)(TM) vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0000533 a rdfs:Class ;
  rdfs:label "vaccine subdominant epitope" ;
  rdfs:subClassOf obo:VO_0000811 .

obo:VO_0007735 a rdfs:Class ;
  rdfs:label "TGFβ2 antisense-GMCSF gene modified autologous tumor cell vaccine" ;
  rdfs:comment "A cancer vaccine made with GMCSF transgene that directly stimulates increased expression of tumor antigen(s) and enhances dendritic cell migration to the vaccination site. TGFβ2 blockade following intracellular TGFβ2 antisense gene expression reduces production of immune inhibiting activity at the vaccine site. This vaccine integrates enhancement of an anticancer immune response concurrently with a reduction in cancer-induced immune suppression. Autologous cancer cells are harvested from patients with advanced refractory cancer, and a TGFβ2 antisense / GMCSF expression vector plasmid is constructed. The autologous cancer tissue is irradiated and electrocorporated with the vector. " ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0011037 a rdfs:Class ;
  rdfs:label "PtxB" ;
  rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model.  These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:VO_0019154 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0019549 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria Quadrivalent 2016-2017 Formula]" ;
  rdfs:subClassOf obo:VO_0003744 , obo:VO_0019544 .

obo:VO_0017914 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injectable Solution [Mastaflu]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017818 .

obo:VO_0003699 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2016-2017 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003698 .

obo:VO_0019101 a rdfs:Class ;
  rdfs:label "oral liquid product" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:VO_0007305 a rdfs:Class ;
  rdfs:label "autologous melanoma lysate-pulsed autologous dendritic cell vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous melanoma cells containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against melanoma cells, which may result in melanoma cell lysis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0011133 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ;
  rdfs:comment "Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later. The mice immunized with HA plasmid once and the NA plasmid twice survived 100% [PubMed: 19067149]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0003121 a rdfs:Class ;
  rdfs:label "OmniHIB vaccine" ;
  rdfs:comment "A Haemophilus influenzae type B conjugate vaccine manufactured by GSB." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0012185 .

obo:VO_0019408 a rdfs:Class ;
  rdfs:label "Bacillus anthracis strain V770-NP1-R antigens 0.1 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0019406 , obo:VO_0019409 .

obo:VO_0003512 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0003497 .

obo:VO_0002985 a rdfs:Class ;
  rdfs:label "Psuedorabies virus glycoprotein M mutant vaccine" ;
  rdfs:comment "A glycoprotein M, gM, deletion in pseudorabies virus was attenuated and induced protection in piglets against intranasal challenge with 108 p.f.u. of the highly virulent PrV strain NIA-3" ;
  rdfs:subClassOf obo:VO_0000750 .

obo:VO_0017338 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0017337 .

obo:VO_0020012 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 158000000 UNT/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 158000000 UNT/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0003180 a rdfs:Class ;
  rdfs:label "TDAP" ;
  rdfs:comment "A vaccine that protects adolescents and adults from tetanus, diphtheria, and pertussis." ;
  rdfs:subClassOf obo:VO_0000641 , obo:VO_0000738 .

obo:VO_0004110 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae Outer Membrane Protein P1 vaccine" ;
  rdfs:subClassOf obo:VO_0012185 .

obo:OPL_0000321 a rdfs:Class ;
  rdfs:label "Mammalia macrophage" ;
  rdfs:comment "A macrophage that is a part of or originated from a mammalia." ;
  rdfs:subClassOf obo:CL_0000235 .

obo:VO_0002467 a rdfs:Class ;
  rdfs:label "Porcine Circovirus Vaccine- Mycoplasma Hyopneumoniae Bactin" ;
  rdfs:subClassOf obo:VO_0000329 , obo:VO_0000563 , obo:VO_0001524 .

obo:VO_0010931 a rdfs:Class ;
  rdfs:label "NP from Zaire ebolavirus" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010769 .

obo:VO_0003602 a rdfs:Class ;
  rdfs:label "influenza B virus B/Maryland/15/2016 antigen" ;
  rdfs:comment "RXAUI: 10279284" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:VO_0004711 a rdfs:Class ;
  rdfs:label "rMV- SARS-CoV -S/Ssol vaccine" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:UBERON_0000165 a rdfs:Class ;
  rdfs:label "mouth" ;
  rdfs:comment "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/issues/661> ;
  rdfs:subClassOf obo:UBERON_0004921 .

obo:VO_0019577 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2020 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020490 .

obo:VO_0007284 a rdfs:Class ;
  rdfs:label "Autologous Dendritic Cell-Adenovirus CCL21 Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of autologous dendritic cells (DCs) that have been transduced ex vivo with an adenoviral vector containing the CCL21 gene with potential immunostimulatory and antineoplastic activities. Upon intratumoral administration, autologous dendritic cell-adenovirus CCL21 vaccine expresses the chemokine CCL21, which may induce an antitumoral cytotoxic immune response in the tumor microenvironment. CCL21 [chemokine (C-C motif) ligand 21] has been shown to attract antigen presenting cells (APCs), like leukocytes and DCs, and natural killer (NK) cells and their T-cell effectors to induce a cytotoxic immune response." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0019260 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Idaho/07/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Indiana/08/2018 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010420 .

obo:VO_0005290 a rdfs:Class ;
  rdfs:label "INI-2002 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0018462 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumopur] Box of 20" ;
  rdfs:subClassOf obo:VO_0018434 , obo:VO_0018446 .

obo:VO_0004487 a rdfs:Class ;
  rdfs:label "Vaccinia virus DNA vaccine tPA-D8L" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000651 .

obo:VO_0001364 a rdfs:Class ;
  rdfs:label "human immunization objective" ;
  rdfs:subClassOf obo:VO_0000585 .

obo:VO_0004534 a rdfs:Class ;
  rdfs:label "IBDV DNA vaccine pCAGVP243-IL-18" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001497 .

obo:VO_0018792 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 25 LFU/ML / Pertussis Vaccine 8 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0016715 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0016678 , obo:VO_0016684 , obo:VO_0016721 .

obo:VO_0018053 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix]" ;
  rdfs:subClassOf obo:VO_0018052 , obo:VO_0018144 .

obo:VO_0020092 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine B/Brisbane/60/2008 antigen 50000000 MG/ML" ;
  rdfs:subClassOf obo:VO_0003523 .

obo:VO_0015641 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat]" ;
  rdfs:subClassOf obo:VO_0015575 , obo:VO_0015669 .

obo:VO_0020038 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001178 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0019905 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Flulaval 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020340 .

obo:VO_0016389 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [H B Vax] Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0015950 .

obo:VO_0003801 a rdfs:Class ;
  rdfs:label "Varicella zoster virus glycoprotein E" ;
  rdfs:comment "RXAUI: 9698276" ;
  rdfs:subClassOf obo:VO_0010792 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity"@en ;
  rdfs:comment "A generically dependent continuant that is about some thing."@en ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:VO_0001195 a rdfs:Class ;
  rdfs:label "vaccination route datum" ;
  rdfs:comment """A measurement datum that represents a specific route (e.g., i.p.) used for vaccination. Different routes can be represented using discretized digitals.  0 = IP; 1 = PO; 2 = SC; 3 = IM; 4 = IN; 6 = IG; 7 = IV; 8 = ID.

""" ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0005058 a rdfs:Class ;
  rdfs:label "pCMV3ISS DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCMV3ISS.  This plasmid is a eukaryotic expression vector." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015111 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015121 , obo:VO_0015280 .

obo:VO_0010859 a rdfs:Class ;
  rdfs:label "EBOV NP" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0019840 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010431 .

obo:VO_0010104 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii MIC11" ;
  rdfs:comment "A MIC11 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0011324 a rdfs:Class ;
  rdfs:label "SREHP" ;
  rdfs:comment "Report describes a recombinant fusion protein containing the serine-rich Entamoeba histolytica protein (SREHP), a protective antigen derived from virulent amebae, and a bacterially derived maltose-binding protein (MBP) from an attenuated strain of Salmonella typhimurium.  Gerbils vaccinated with S typhimurium SREHP-MBP were protected against amebic liver abscess after challenge with E. histolytica, the most common extraintestinal complication of amebiasis [PubMed: 8613356]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010852 .

obo:VO_0019706 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0006052 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine D614 prefusion spike recombinant protein subunit (CoV2 preS dTM) AS03 adjuvant added preservative free 10mcg/0.5mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005267 , obo:VO_0005269 .

obo:NCBITaxon_9103 a rdfs:Class ;
  rdfs:label "Meleagris gallopavo" ;
  rdfs:subClassOf obo:NCBITaxon_9005 .

obo:VO_0019158 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.006 MG/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Vaxelis]" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0000746 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0001410 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi gene" ;
  rdfs:comment "A bacterial gene that is from Borrelia burgdorferi." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0020663 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] Box of 6 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020662 .

obo:VO_0015973 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015644 , obo:VO_0016057 .

obo:VO_0019896 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Fluzone 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019889 , obo:VO_0020481 .

obo:VO_0002485 a rdfs:Class ;
  rdfs:label "porcine parvovirus-erysipelothrix rhusiopathiae vaccine" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0001456 , obo:VO_0001474 , obo:VO_0001494 .

obo:VO_0010174 a rdfs:Class ;
  rdfs:label "human papilloma virus vaccine, bivalent" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010446 .

obo:NCBITaxon_1385 a rdfs:Class ;
  rdfs:label "Bacillales" ;
  rdfs:subClassOf obo:NCBITaxon_91061 .

obo:VO_0006012 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 .

obo:VO_0006001 a rdfs:Class ;
  rdfs:label "botulinum antitoxin" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0012187 .

obo:VO_0015920 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 2" ;
  rdfs:subClassOf obo:VO_0015631 , obo:VO_0015685 , obo:VO_0016028 .

obo:OPL_0000385 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii sporozoite" ;
  rdfs:comment "A Plasmodium yoelii in sporozoite stage." ;
  rdfs:subClassOf obo:NCBITaxon_5861 , obo:OPL_0000278 .

obo:VO_0003544 a rdfs:Class ;
  rdfs:label "Rubulavirus vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Rubulavirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0002503 a rdfs:Class ;
  rdfs:label "Streptococcus gene" ;
  rdfs:comment "A bacterial gene that is from Streptococcus." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0020202 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.1 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020201 .

obo:VO_0017831 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Prefilled Syringe [ActHIB]" ;
  rdfs:subClassOf obo:VO_0000004 , obo:VO_0010444 , obo:VO_0017888 .

obo:VO_0016943 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxin 10 LFU/ML Injectable Suspension Box of 5 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016942 .

obo:OBI_0000852 a rdfs:Class ;
  rdfs:label "record of missing knowledge" ;
  rdfs:comment "An information content entity created to indicate that information about something is not available to the person recording it."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0017262 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.0055 MG / Bordetella pertussis 0.01 MG / diphtheria toxoid vaccine, inactivated 2 UNT / tetanus toxoid vaccine, inactivated 20 UNT Injection" ;
  rdfs:subClassOf obo:VO_0017230 .

obo:VO_0007244 a rdfs:Class ;
  rdfs:label "ALVAC-CEA vaccine" ;
  rdfs:comment "A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus, encoding for the tumor associated antigen (TAA) carcinoembryonic antigen (CEA), with potential antineoplastic activity. Upon administration, ALVAC-CEA vaccine expresses CEA and may stimulate a host immune response against tumor cells expressing CEA. This may result in the inhibition of tumor growth and/or metastasis. CEA is overexpressed in a variety of tumor cell types." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0003868 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.07 MG/ML [Hiberix]" ;
  rdfs:subClassOf obo:VO_0010715 .

obo:VO_0007583 a rdfs:Class ;
  rdfs:label "Bacillus Calmette-Guerin (BCG), Corynebacterium parvum vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0003728 a rdfs:Class ;
  rdfs:label "Afluria 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003727 .

obo:VO_0003922 a rdfs:Class ;
  rdfs:label "Fluad 2016-2017 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003920 .

obo:VO_0019143 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0005289 a rdfs:Class ;
  rdfs:label "INI-2004 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017006 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0017004 .

obo:VO_0016027 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015667 , obo:VO_0015777 .

obo:VO_0004662 a rdfs:Class ;
  rdfs:label "rVSVDeltaG-ANDV-GPC vaccine" ;
  rdfs:subClassOf obo:VO_0012167 .

obo:VO_0007597 a rdfs:Class ;
  rdfs:label "dendritic cell-Idiotype-Keyhole Limpet Hemocyanin vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0000184 a rdfs:Class ;
  rdfs:label "Ebola virus gene" ;
  rdfs:subClassOf obo:VO_0000156 .

obo:DOID_1936 a rdfs:Class ;
  rdfs:label "atherosclerosis"@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:VO_0003016 a rdfs:Class ;
  rdfs:label "intragastric route" ;
  rdfs:comment "A route of administration that located in the stomach, so that the material is taken into body through stomach directly. " ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0019825 a rdfs:Class ;
  rdfs:label "influenza A virus A/North Carolina/04/2016 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Injectable Suspension [Flucelvax Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020331 .

obo:VO_0016415 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 3 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015960 , obo:VO_0015966 .

obo:VO_0018151 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 10" ;
  rdfs:subClassOf obo:VO_0018150 , obo:VO_0018155 .

obo:VO_0015984 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015648 , obo:VO_0015764 , obo:VO_0016062 .

obo:VO_0017647 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [Tetamun]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:NCBITaxon_2559587 a rdfs:Class ;
  rdfs:label "Riboviria" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:NCBITaxon_90062 a rdfs:Class ;
  rdfs:label "Leptospira interrogans serovar Icterohaemorrhagiae" ;
  rdfs:subClassOf obo:NCBITaxon_173 .

obo:VO_0019856 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:VO_0018422 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23]" ;
  rdfs:subClassOf obo:VO_0018383 , obo:VO_0018386 .

obo:VO_0003291 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003346 .

obo:VO_0017178 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017171 .

obo:VO_0017259 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [Triaxis]" ;
  rdfs:subClassOf obo:VO_0017799 , obo:VO_0018770 .

obo:VO_0003193 a rdfs:Class ;
  rdfs:label "Meningococcal Conjugate and Haemophilis B Vaccine foreign to USA" ;
  rdfs:comment "A Meningicoccal Conjugate and Haemophilis B Vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0003192 , obo:VO_0003444 , obo:VO_0010437 , obo:VO_0010444 .

obo:VO_0016794 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0016722 , obo:VO_0016736 , obo:VO_0016819 .

obo:VO_0016069 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 25 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015866 .

obo:VO_0000032 a rdfs:Class ;
  rdfs:label "DNA vaccine" ;
  rdfs:comment "A vaccine that is composed of a plasmid vaccine vector (a circular double stranded DNA molecule) containing the whole of parts of genes encoding one or more vaccine antigen proteins." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:VO_0001504 a rdfs:Class ;
  rdfs:label "Feline infectious peritonitis virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Feline infectious peritonitis virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0004897 .

obo:VO_0018176 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0018174 , obo:VO_0018175 , obo:VO_0018182 .

obo:VO_0018712 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Suspension [RUDIVAX]" ;
  rdfs:subClassOf obo:VO_0003112 , obo:VO_0018711 .

obo:VO_0020850 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Xanaflu]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0019245 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0020304 .

obo:VO_0005273 a rdfs:Class ;
  rdfs:label "QazCoVac-P vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by the Research Institute for Biological Safety Problems in Kazakhstan" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0019566 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flulaval Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020343 .

obo:VO_0004918 a rdfs:Class ;
  rdfs:label "vaccine specific interleukin-10 response" ;
  rdfs:comment "vaccine-induced T-helper 2 type immune response that is indicated by the presence of interleukin-10 production" ;
  rdfs:subClassOf obo:VO_0000101 .

obo:VO_0001469 a rdfs:Class ;
  rdfs:label "duck vaccine" ;
  rdfs:comment "Vaccine that used for immunizing duck." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001461 .

obo:VO_0010844 a rdfs:Class ;
  rdfs:label "Dengue Virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0016298 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016027 .

obo:VO_0002456 a rdfs:Class ;
  rdfs:label "Newcastle Disease-Fowlpox vaccine" ;
  rdfs:subClassOf obo:VO_0000985 , obo:VO_0001222 .

obo:VO_0018385 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Injectable Solution [Pneumopur]" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:VO_0004749 a rdfs:Class ;
  rdfs:label "rMDV-IBDV-VP2 vaccine" ;
  rdfs:subClassOf obo:VO_0001497 .

obo:VO_0003404 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0001240 a rdfs:Class ;
  rdfs:label "aluminum potassium sulfate adjuvant" ;
  rdfs:comment "An aluminum vaccine adjuvant that is aluminum potassium sulfate (AlK(SO4)2)." ;
  rdfs:subClassOf obo:VO_0000884 .

obo:VO_0004823 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G2 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010449 .

obo:VO_0020028 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0011075 a rdfs:Class ;
  rdfs:label "GroEL from Francisella tularensis" ;
  rdfs:comment "Researchers have shown that mice that had been immunized with purified heat shock protein 60 (Hsp60, groEL) isolated from Francisella tularensis were protected against a subsequent challenge with some strains of the bacterium [PubMed: 15213156]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:VO_0004518 a rdfs:Class ;
  rdfs:label "B16 melanoma DNA vaccine pSin-mTRP-1" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0010259 a rdfs:Class ;
  rdfs:label "vaccine preservative variable" ;
  rdfs:comment "A variable representing the vaccine preservative " ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0003688 a rdfs:Class ;
  rdfs:label "Fluvirin 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003687 .

obo:VO_0002898 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium IppA/IppB/msbB" ;
  rdfs:comment "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" .

obo:VO_0005409 a rdfs:Class ;
  rdfs:label "mRNA-1073 vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine by Moderna that combines the mRNA-1273 COVID-19 vaccine and the mRNA-1010 influenza vaccine." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0005017 a rdfs:Class ;
  rdfs:label "Synchotrope TA2M DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label Synchotrope TA2M.  This plasmid is 3683 base pairs in length and has two copies of the murine CpG immune stimulatory sequence AACGTT inserted." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000087 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum vaccine" ;
  rdfs:comment "a malaria vaccine that protects against malaria caused by Plasmodium falciparum." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000761 .

obo:VO_0007424 a rdfs:Class ;
  rdfs:label "MUC1-targeted peptide GO-203-2C vaccine" ;
  rdfs:comment "Gene name: MUC1" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0015509 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0003423 .

obo:VO_0003191 a rdfs:Class ;
  rdfs:label "Pneumococcal vaccine foreign to USA" ;
  rdfs:comment "A pneumococcal vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0003444 , obo:VO_0010453 .

obo:VO_0002679 a rdfs:Class ;
  rdfs:label "obsolete senA from Shigella" ;
  rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" .

obo:VO_0000226 a rdfs:Class ;
  rdfs:label "hypersensitivity to polymyxin" ;
  rdfs:subClassOf obo:VO_0000224 .

obo:VO_0000949 a rdfs:Class ;
  rdfs:label "Mycoplasma gallisepticum vaccine" ;
  rdfs:comment "a bacterial vaccine against Mycoplasma gallisepticum infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000604 .

obo:VO_0020547 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluad]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020856 .

obo:VO_0010451 a rdfs:Class ;
  rdfs:label "licensed human salmonella typhi vaccine" ;
  rdfs:comment "Salmonella typhi vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000671 .

obo:UBERON_0000064 a rdfs:Class ;
  rdfs:label "organ part" ;
  rdfs:comment "A multicellular structure that is a part of an organ." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:VO_0019415 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.0468 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.0468 MG/ML / diphtheria toxoid vaccine, inactivated 13.4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Tripedia]" ;
  rdfs:subClassOf obo:VO_0000112 , obo:VO_0000561 , obo:VO_0001214 .

obo:NCBITaxon_1313 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:VO_0004444 a rdfs:Class ;
  rdfs:label "Neuroblastoma DNA vaccine HuDsec" ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0001443 a rdfs:Class ;
  rdfs:label "Rabies virus gene" ;
  rdfs:comment "A viral gene that is from Rabies virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0001353 a rdfs:Class ;
  rdfs:label "cytokine vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that contains active cytokine compound." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0020242 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0020451 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0020415 , obo:VO_0020427 .

obo:VO_0001565 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0000987 , obo:VO_0001220 .

obo:VO_0020674 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension by Lamepro" ;
  rdfs:subClassOf obo:VO_0020668 .

obo:VO_0005232 a rdfs:Class ;
  rdfs:label "EuCorVac-19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine by EuBiologics Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0019955 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Flulaval 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019952 , obo:VO_0020339 .

obo:VO_0007189 a rdfs:Class ;
  rdfs:label "12 melanoma peptide vaccine" ;
  rdfs:comment "Melonoma vaccine that uses 12 class I major histocompatibility complex-restricted melanoma peptides (12MP) from cancer-testis antigens (CTAs) and melanocytic differentiation proteins (MDPs)." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0019634 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2021 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020492 .

obo:VO_0020407 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0020387 , obo:VO_0020414 .

obo:NCBITaxon_11072 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus" ;
  rdfs:subClassOf obo:NCBITaxon_3044782 .

obo:VO_0002798 a rdfs:Class ;
  rdfs:label "Streptococcus equi vicK mutant vaccine" ;
  rdfs:comment "A vicK mutant is attenuated in mice and induced protection from challenge with wild type S. equi" ;
  rdfs:subClassOf obo:VO_0000948 .

obo:OBI_0000725 a rdfs:Class ;
  rdfs:label "host role" ;
  rdfs:comment "host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0003789 a rdfs:Class ;
  rdfs:label "influenza B virus B/Hong Kong/259/2010 antigen" ;
  rdfs:comment "CUI: C4276030" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:VO_0002797 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus aroA mutant vaccine" ;
  rdfs:comment "An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. aureus" ;
  rdfs:subClassOf obo:VO_0002502 .

obo:PATO_0001995 a rdfs:Class ;
  rdfs:label "organismal quality" ;
  rdfs:comment "A quality that inheres in an entire organism or part of an organism." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:VO_0004302 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pHA/NP147-155 encoding NP147-155" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0001693 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 1 & 3, Live Virus Vaccine (USDA: 16G1.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0017416 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0018795 .

obo:VO_0016895 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection Box of 5" ;
  rdfs:subClassOf obo:VO_0016892 , obo:VO_0017267 .

obo:VO_0010010 a rdfs:Class ;
  rdfs:label "Giardia  lamblia a1-giardin" ;
  rdfs:comment "A a1-giardin protein that is part of Giardia  lamblia" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015483 .

obo:VO_0003415 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Product" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:NCBITaxon_11588 a rdfs:Class ;
  rdfs:label "Rift Valley fever virus" ;
  rdfs:subClassOf obo:NCBITaxon_1980410 .

obo:VO_0007294 a rdfs:Class ;
  rdfs:label "Autologous Expanded Mesenchymal Stem Cells OTI-010 Vaccine" ;
  rdfs:comment "Multipotent self-renewing adherent non-hematopoietic stromal cells harvested from a patient's bone marrow and grown in vitro. When injected back into the patient, autologous expanded mesenchymal stem cells OTI-010 may differentiate into various mesenchyme-derived cell types and, in some instances, may augment bone marrow engraftment after whole-body irradiation." ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0002316 a rdfs:Class ;
  rdfs:label "Porcine Circovirus Type 2, Killed Baculovirus Vector Vaccine- Mycoplasma Hyopneumoniae Bacterin (USDA: 49K5.R1)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002467 , obo:VO_0007748 .

obo:VO_0016365 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0002055 a rdfs:Class ;
  rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002385 , obo:VO_0007748 .

obo:VO_0001883 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4089.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002336 .

obo:VO_0020033 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe [Fluarix 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020028 , obo:VO_0020315 .

obo:VO_0015277 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension [Havrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015276 , obo:VO_0015278 .

obo:VO_0019515 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen (isoform L), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform M), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform S), recombinant 0.01 MG/ML Injection [Prehevbrio]" ;
  rdfs:subClassOf obo:VO_0019514 .

obo:VO_0001327 a rdfs:Class ;
  rdfs:label "Brucella melitensis DNA vaccine encoding Bp26 and Tf" ;
  rdfs:subClassOf obo:VO_0001226 .

obo:VO_0002355 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002488 .

obo:VO_0020172 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020168 .

obo:VO_0011508 a rdfs:Class ;
  rdfs:label "Classical swine fever virus vaccine VAC-E2" ;
  rdfs:subClassOf obo:VO_0001012 .

obo:VO_0016252 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0015918 .

obo:VO_0019180 a rdfs:Class ;
  rdfs:label "0.5 ML human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML / human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019539 .

obo:VO_0010305 a rdfs:Class ;
  rdfs:label "influenza B virus B/Phuket/3073/2013 antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003519 , obo:VO_0010301 .

obo:VO_0001649 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.41)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0019194 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019670 .

obo:VO_0019885 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Flulaval Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020342 .

obo:VO_0018125 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella virus vaccine Injection [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018122 .

obo:VO_0002462 a rdfs:Class ;
  rdfs:label "Parvovirus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002463 .

obo:VO_0005390 a rdfs:Class ;
  rdfs:label "LQ vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0005082 a rdfs:Class ;
  rdfs:label "Abdala vaccine" ;
  rdfs:comment "An authorized SARS-CoV-2 protein subunit vaccine based on recombinant RBD subunits manufactured by the Center for Genetic Engineering and Biotechnology (CIGB)." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0017273 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.008 MG / Bordetella pertussis 0.05 MG / diphtheria toxoid vaccine, inactivated 30 UNT / tetanus toxoid vaccine, inactivated 40 UNT Injectable Solution [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017226 , obo:VO_0017272 .

obo:VO_0005501 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum MSA2" ;
  rdfs:subClassOf obo:VO_0015471 .

obo:VO_0019845 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe [Afluria 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003733 , obo:VO_0019844 .

obo:VO_0004862 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010290 , obo:VO_0010444 .

obo:VO_0003739 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2016-2017 Formula Injectable Product" ;
  rdfs:subClassOf obo:VO_0003744 .

obo:VO_0010275 a rdfs:Class ;
  rdfs:label "assay  measurement sample  interval" ;
  rdfs:comment "A measurment datum that records the time point between the start of a first intervention in a planned process and the measurment of a sample." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0010978 a rdfs:Class ;
  rdfs:label "GNA33" ;
  rdfs:comment "Protective antigen [PubMed: 10710308]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0005345 a rdfs:Class ;
  rdfs:label "PIKA Recombinant COVID-19 Vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine by Yisheng Biopharma" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005267 , obo:VO_0005269 .

obo:VO_0017230 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0018751 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Intramuscular Solution [Typherix]" ;
  rdfs:subClassOf obo:VO_0010744 , obo:VO_0018750 .

obo:VO_0015252 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015249 .

obo:VO_0003593 a rdfs:Class ;
  rdfs:label "Fluzone 2017-2018 high-dose vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003592 .

obo:VO_0016218 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:NCBITaxon_777 a rdfs:Class ;
  rdfs:label "Coxiella burnetii" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:VO_0000668 a rdfs:Class ;
  rdfs:label "CVD 1208S vaccine" ;
  rdfs:comment "CVD 1208S is the same thing as CVD 1208, but CVD 1208S was prepared using animal-free media." ;
  rdfs:subClassOf obo:VO_0000680 , obo:VO_0001217 .

obo:VO_0018292 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe [Rabipur]" ;
  rdfs:subClassOf obo:VO_0018278 , obo:VO_0018296 .

obo:VO_0003985 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Adacel]" ;
  rdfs:subClassOf obo:VO_0000005 .

obo:VO_0018806 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010448 .

obo:VO_0000072 a rdfs:Class ;
  rdfs:label "Menomune A/C/Y/W-135 vaccine" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0000714 , obo:VO_0010289 , obo:VO_0010290 , obo:VO_0010444 .

obo:VO_0000564 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis secA2 mutant vaccine" ;
  rdfs:comment "Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Guerin vaccination" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0017062 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution [Tetamun]" ;
  rdfs:subClassOf obo:VO_0017061 , obo:VO_0017539 .

obo:VO_0002192 a rdfs:Class ;
  rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.29)" .

obo:VO_0019749 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020495 .

obo:VO_0016484 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0001113 a rdfs:Class ;
  rdfs:label "CoxAbic vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001125 .

obo:VO_0005262 a rdfs:Class ;
  rdfs:label "MVA-SARS-2-ST vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine by the German Center for Infection Research" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0020113 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain / mumps virus vaccine live, Jeryl Lynn strain / rubella virus vaccine live (Wistar RA 27-3 strain) / varicella-zoster virus vaccine live (Oka-Merck) strain Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000737 .

obo:VO_0004656 a rdfs:Class ;
  rdfs:label "rBCGpMV362-TgCyP vaccine" ;
  rdfs:subClassOf obo:VO_0000994 .

obo:VO_0010997 a rdfs:Class ;
  rdfs:label "IroN from Salmonella spp." ;
  rdfs:comment "Thirty-day-old chickens were immunized intramuscularly with purified IroN from Salmonella Typhimurium mixed with Freund's incomplete adjuvant; the chickens were then challenged intravenously with Salmonella Enteritidis. The mortality rate of immunized chickens was 10%. On the other hand, that of control chickens was 80% [PubMed: 20095157]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010776 .

obo:VO_0003872 a rdfs:Class ;
  rdfs:label "COMVAX Injection 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003871 , obo:VO_0020832 .

obo:VO_0001296 a rdfs:Class ;
  rdfs:label "recombinant hIFN-gamma/Interferon-g vaccine adjuvant" ;
  rdfs:comment "An IFN-gamma vaccine adjuvant that is composed of recombinant hIFN-gamma." ;
  rdfs:subClassOf obo:VO_0001360 .

obo:VO_0000617 a rdfs:Class ;
  rdfs:label "vaccine component role" ;
  rdfs:comment "A role that inheres in a material entity that becomes an ingredient of a vaccine. " ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0016974 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.02 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017437 .

obo:VO_0010248 a rdfs:Class ;
  rdfs:label "pathogen strain variable" ;
  rdfs:comment "A variable representing the lineage of pathogen strain (incljuding presence or absence of virulence factors)" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0015544 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injection [H-B-Vax II]" ;
  rdfs:subClassOf obo:VO_0003421 .

obo:VO_0003481 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010304 , obo:VO_0010415 .

obo:VO_0006041 a rdfs:Class ;
  rdfs:label "Pneumococcal conjugate vaccine 15-valent (PCV15) polysaccharide CRM197 conjugate adjuvant preservative free" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010453 .

obo:VO_0015135 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015134 , obo:VO_0015138 , obo:VO_0015302 .

obo:VO_0004558 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda DNA vaccine pCEsa1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002506 .

obo:NCBITaxon_11089 a rdfs:Class ;
  rdfs:label "Yellow fever virus" ;
  rdfs:subClassOf obo:NCBITaxon_3044782 .

obo:VO_0004573 a rdfs:Class ;
  rdfs:label "Yersinia pestis DNA vaccine YscF-2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000648 .

obo:VO_0001515 a rdfs:Class ;
  rdfs:label "Bluetongue virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Bluetongue virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003542 .

obo:VO_0011183 a rdfs:Class ;
  rdfs:label "P67" ;
  rdfs:comment "Immunization with recombinant forms of a sporozoite surface antigen (r-p67), derived from either bacterial or insect cells, induces high levels of sporozoite neutralizing antibodies in cattle.In vivo immunization studies have shown that approximately 30% of immunized cattle are nonreactors to a needle LD70 sporozoite challenge, 40% experience a mild disease reaction from which they recover, and the remaining 30% suffer severe disease and are clinically indistinguishable from controls. Transient parasitosis and mild clinical reactions are also observed in challenge of cattle immunized by infection and treatment and such responses constitute immunity to ECF. Hence, p67 is able to routinely induce immunity at a level of about 70% [PubMed: 11193661]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010824 .

obo:VO_0016209 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0017968 a rdfs:Class ;
  rdfs:label "0.6 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Menjugate] Box of 1" ;
  rdfs:subClassOf obo:VO_0017940 , obo:VO_0017951 .

obo:VO_0000049 a rdfs:Class ;
  rdfs:label "Gardasil vaccine" ;
  rdfs:comment """Quadrivalent vaccine meaning it protects against 4 strains of virus (types 6, 11, 16, and 18). The vaccine was made using genetic engineering techniques. The genes that encode a specific protein from each of these strains are expressed in yeast in large-scale fermentation cultures. Protein purification methods are then used to isolate the proteins and make the vaccine.
Cited from: 
http://biotech.about.com/b/2008/09/03/gardasil-safety-of-genetically-engineered-hpv-vaccine-still-in-question.htm""" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000556 , obo:VO_0000667 , obo:VO_0000714 , obo:VO_0010446 .

obo:VO_0003753 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003751 .

obo:VO_0004385 a rdfs:Class ;
  rdfs:label "Ebola virus DNA vaccine DNA/rAd5 encoding ZEBOV and SEBOV antigens" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000726 .

obo:OPL_0000162 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum exflagellated microgametocyte" ;
  rdfs:comment "A Plasmodium falciparum microgametocyte that is matured with flagellated motile microgametes still attached to its central body. Exflagellated microgametocyte of Plasmodium falciparum is found in the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000050 .

obo:VO_0016263 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 3 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015922 .

obo:VO_0015190 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0015179 , obo:VO_0015274 .

obo:VO_0020864 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Stada] Box of 10" ;
  rdfs:subClassOf obo:VO_0020863 , obo:VO_0020884 .

obo:VO_0017495 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 50" ;
  rdfs:subClassOf obo:VO_0017489 , obo:VO_0017501 .

obo:NCBITaxon_8022 a rdfs:Class ;
  rdfs:label "Oncorhynchus mykiss" ;
  rdfs:subClassOf obo:NCBITaxon_504568 .

obo:VO_0018140 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 17500 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018139 .

obo:VO_0002445 a rdfs:Class ;
  rdfs:label "fowlpox-Mycoplasma Gallisepticum vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000563 , obo:VO_0000985 , obo:VO_0001468 .

obo:NCBITaxon_5761 a rdfs:Class ;
  rdfs:label "Naegleria" ;
  rdfs:subClassOf obo:NCBITaxon_2611352 .

obo:VO_0016223 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:VO_0000144 a rdfs:Class ;
  rdfs:label "alphavirus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses an alphavirus as the vector." ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0002164 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.18)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0003420 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0004123 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis DNA vaccine pAK4-sod" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:VO_0005091 a rdfs:Class ;
  rdfs:label "LV-SMENP-DC vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant vector vaccine by Shenzhen Geno-Immune Medical Institute" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0007098 a rdfs:Class ;
  rdfs:label "prime/boost DC-TRP-2 melanoma vaccine" ;
  rdfs:comment "rime/boost vaccination proved to be of no advantage or even detrimental in therapeutic settings in B16F1 and transgenic adenocarcinoma of the mouse prostate (TRAMP) models, respectively" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0004433 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine pCR3.1-VS-HSP65-TP-GRP6-M2 encoding 6 tandem repeats of GRP" ;
  rdfs:comment "Gene name: GRP" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:NCBITaxon_7742 a rdfs:Class ;
  rdfs:label "Vertebrata <vertebrates>" ;
  rdfs:subClassOf obo:NCBITaxon_33213 .

obo:VO_0007385 a rdfs:Class ;
  rdfs:label "fowlpox-NY-ESO-1 vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant fowlpox virus vector encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1, an antigen found in normal testis and various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. Vaccination with NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005425 , obo:VO_0005484 , obo:VO_0005485 , obo:VO_0005499 , obo:VO_0007657 .

obo:VO_0004172 a rdfs:Class ;
  rdfs:label "Leishmania major DNA vaccine encoding SP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001231 .

obo:VO_0000256 a rdfs:Class ;
  rdfs:label "pET21a DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002045 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1288.44)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0004334 a rdfs:Class ;
  rdfs:label "Ebola virus DNA vaccine GP DNA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000726 .

obo:VO_0020994 a rdfs:Class ;
  rdfs:label "Influenza Virus Vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.00752 MG/ML" ;
  rdfs:subClassOf obo:VO_0003504 .

obo:VO_0004023 a rdfs:Class ;
  rdfs:label "Leishmania donovani Beta-tubulin protein vaccine" ;
  rdfs:subClassOf obo:VO_0001142 .

obo:VO_0005132 a rdfs:Class ;
  rdfs:label "rVV-SARS vaccine" ;
  rdfs:comment "A MERS DNA vaccine made of plasmid vaccines that encoded S1 subunit only" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0004856 a rdfs:Class ;
  rdfs:label "ACAM2000 Injectable Product" ;
  rdfs:subClassOf obo:VO_0000003 .

obo:VO_0018591 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0018768 .

obo:VO_0020700 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017679 .

obo:VO_0006081 a rdfs:Class ;
  rdfs:label "Tick-borne encephalitis vaccine unspecified" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000952 .

obo:VO_0002451 a rdfs:Class ;
  rdfs:label "Mink Enteritis Vaccine-Clostridium Botulinum Type C Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0001493 , obo:VO_0012187 .

obo:VO_0019346 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Prefilled Syringe [Ipol]" ;
  rdfs:subClassOf obo:VO_0019345 , obo:VO_0020174 .

obo:VO_0011558 a rdfs:Class ;
  rdfs:label "Ixiaro vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000665 , obo:VO_0000712 , obo:VO_0000714 , obo:VO_0010440 .

obo:VO_0010220 a rdfs:Class ;
  rdfs:label "tetanus toxoid, adsorbed" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003396 , obo:VO_0010436 .

obo:VO_0011096 a rdfs:Class ;
  rdfs:label "US6 from Herpes simplex virus type 1 and 2" ;
  rdfs:comment "The herpes simplex virus type 2 (HSV-2) glycoprotein D (gD2) gene was inserted into an intergenic site in the unique short region of the Oka VZV genome. Expression of gD2 in cells infected with the recombinant Oka strain VZV (ROka-gD2) was confirmed by antibody staining of fixed cells and by immunoblot analysis.  Forty days after the third inoculation, guinea pigs were challenged intravaginally with HSV-2. Inoculation of guinea pigs with ROka-gD2 significantly reduced the severity of primary HSV-2 infection (P < 0.001) [PubMed: 7494331]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010834 .

obo:VO_0004860 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0019926 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Prefilled Syringe [Fluarix 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019923 , obo:VO_0020316 .

obo:VO_0015599 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015555 .

obo:VO_0010718 a rdfs:Class ;
  rdfs:label "Inactivated Poliomyelitis vaccine - IPV" ;
  rdfs:comment "A poliovirus vaccine that contains inactivtated Poliomyelitis to prevent disease caused from the vaccine." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000714 , obo:VO_0010447 .

obo:VO_0015872 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015615 , obo:VO_0015694 , obo:VO_0015997 .

obo:VO_0019718 a rdfs:Class ;
  rdfs:label "influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Injectable Suspension [Afluria Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0020305 .

obo:VO_0003497 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003499 , obo:VO_0010415 .

obo:VO_0021004 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 UNT Injection" ;
  rdfs:subClassOf obo:VO_0021001 .

obo:VO_0007464 a rdfs:Class ;
  rdfs:label "HLA-A2402-restricted VEGFR1/2 multipeptide vaccine" ;
  rdfs:comment "A cancer vaccine containing two HLA-A*0201-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this vaccine are derived from: vascular endothelial growth factor receptors (VEGFR) 1 and 2. Upon administration, HLA-A*0201-restricted VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing VEGFR 1 and 2 peptides, resulting in tumor cell lysis and decreased tumor growth. HLA-A*0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005486 , obo:VO_0005489 , obo:VO_0005490 , obo:VO_0007657 .

obo:VO_0010425 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2021" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0017520 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML [Tetravac]" ;
  rdfs:subClassOf obo:VO_0017519 .

obo:VO_0001897 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002343 .

obo:VO_0016942 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxin 10 LFU/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0016941 , obo:VO_0017404 .

obo:VO_0003832 a rdfs:Class ;
  rdfs:label "Havrix, Hepatitis A Vaccine (Inactivated), (Adult Dose) 1 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0003833 .

obo:VO_0012213 a rdfs:Class ;
  rdfs:label "allergy vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a Allergy vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0015095 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Epaxal]" ;
  rdfs:subClassOf obo:VO_0015094 , obo:VO_0015253 .

obo:VO_0020655 a rdfs:Class ;
  rdfs:label "1 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0020646 , obo:VO_0021018 .

obo:VO_0019631 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020489 .

obo:VO_0004873 a rdfs:Class ;
  rdfs:label "Adenovirus Type 4 Vaccine Live Pill" ;
  rdfs:subClassOf obo:VO_0004872 .

obo:VO_0021139 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020326 .

obo:VO_0000876 a rdfs:Class ;
  rdfs:label "pCMV/ER-PA83 vaccine" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:NCBITaxon_400570 a rdfs:Class ;
  rdfs:label "Quailpox virus" ;
  rdfs:subClassOf obo:NCBITaxon_10260 .

obo:VO_0016883 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0016877 .

obo:VO_0002718 a rdfs:Class ;
  rdfs:label "UL47 from Gallid herpesvirus 1" ;
  rdfs:comment "A UL47 mutant in avian infectious laryngotracheitis virus is attenuated and provides protection in chicken against subsequent challenge infection with virulent ILTV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001435 .

obo:VO_0000447 a rdfs:Class ;
  rdfs:label "poxvirus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses an poxvirus as the vector." ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0011086 a rdfs:Class ;
  rdfs:label "G1" ;
  rdfs:comment "Study used a deer mouse infection model to test the protective efficacy of genetic vaccine candidates for Sin Nombre (SN) virus that were known to provoke immunological responses in BALB/c mice.  Protective epitopes were localized in each of four overlapping cDNA fragments that encoded portions of the SN virus G1 glycoprotein antigen; the nucleocapsid gene also was protective [PubMed: 12075094]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010768 .

obo:VO_0015241 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015237 .

obo:VO_0016354 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:VO_0020592 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] Box of 50" ;
  rdfs:subClassOf obo:VO_0020587 , obo:VO_0020608 , obo:VO_0020879 .

obo:VO_0020467 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typherix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020448 .

obo:VO_0007283 a rdfs:Class ;
  rdfs:label "Autologous Dendritic Cell Vaccine ACT2001" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous, immature dendritic cells (DCs), with potential immunostimulating and antineoplastic activities. Upon leukapheresis, immature DCs are isolated and re-administered intra-tumorally. The immature DCs internalize and process the tumor-associated antigens (TAAs), migrate to the lymphatic system, and then expose the immune system to the TAAs. This induces a specific cytotoxic T-lymphocyte (CTL) response against the cancer cells leading to tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005491 , obo:VO_0007657 .

obo:VO_0016398 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015956 , obo:VO_0015962 .

obo:VO_0019465 a rdfs:Class ;
  rdfs:label "BCG, live, Tice strain" ;
  rdfs:subClassOf obo:VO_0000771 .

obo:VO_0019440 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 13.2 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0018301 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 1" ;
  rdfs:subClassOf obo:VO_0018276 , obo:VO_0018310 .

obo:VO_0005489 a rdfs:Class ;
  rdfs:label "colon cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against colon cancer." ;
  rdfs:subClassOf obo:VO_0000177 , obo:VO_0005426 .

obo:NCBITaxon_75985 a rdfs:Class ;
  rdfs:label "Mannheimia haemolytica" ;
  rdfs:subClassOf obo:NCBITaxon_712 .

obo:VO_0015866 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 25" ;
  rdfs:subClassOf obo:VO_0015613 , obo:VO_0015687 , obo:VO_0015995 .

obo:VO_0004722 a rdfs:Class ;
  rdfs:label "rVCG- MOMP/HSV-2-gD vaccine" ;
  rdfs:subClassOf obo:VO_0001207 .

obo:VO_0020626 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0020623 .

obo:VO_0002339 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Haemophilus Somnus Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0002338 , obo:VO_0003535 .

obo:VO_0015334 a rdfs:Class ;
  rdfs:label "Hepatitis A Virus / Salmonella Typhi Inactivated Antigen Injection [Vivaxim]" ;
  rdfs:subClassOf obo:VO_0010748 , obo:VO_0015333 .

obo:VO_0001522 a rdfs:Class ;
  rdfs:label "avian encephalomyelitis virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Avian Encephalomyelitis Virus infection" ;
  rdfs:subClassOf obo:VO_0000609 , obo:VO_0001461 .

obo:VO_0011100 a rdfs:Class ;
  rdfs:label "ICP27 from Herpes simplex virus type 2" ;
  rdfs:comment "Particle-mediated DNA vaccination of mice with a DNA plasmid-encoding ICP27 resulted in the induction of ICP27-specific IFN-gamma and TNF-alpha production in Balb/c mice.  When the DNA vaccine was supplemented with as little as 50ng of a vector encoding the A and B subunits of the Escherichia coli heat labile enterotoxin (LT), animals were profoundly protected from morbidity and mortality [PubMed: 16621198]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010834 .

obo:VO_0003017 a rdfs:Class ;
  rdfs:label "intragastric injection route" ;
  rdfs:comment "An intragastric route that has a vaccine injection site located in stomach." ;
  rdfs:subClassOf obo:VO_0003016 .

obo:VO_0004603 a rdfs:Class ;
  rdfs:label "AE-Poxine vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001522 .

obo:VO_0017748 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] Box of 10" ;
  rdfs:subClassOf obo:VO_0017747 , obo:VO_0017751 .

obo:VO_0005457 a rdfs:Class ;
  rdfs:label "DTP-Haemophilus influenzae type b conjugate and hepatitis B vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000738 , obo:VO_0010439 .

obo:VO_0019708 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0005193 a rdfs:Class ;
  rdfs:label "COVAX-19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine developed by Vaxine Pty Ltd and CinnaGen Co. and adjuvanted with Advax" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0007345 a rdfs:Class ;
  rdfs:label "autologous, dnp-modified ovarian cancer vaccine" ;
  rdfs:comment "A cancer vaccine made from the patient's own tumor tissue may stimulate an immune response against the patient's tumor cells. O-Vax nay induce a DTH response to autologous, DNP-modified ovarian cancer cells. The vaccine includes DNP-modified autologous ovarian tumor cells followed by cyclophosphamide then weekly doses of DNP-modified autologous ovarian tumor cells mixed with Bacillus of Calmette and Guérin (BCG)." ;
  rdfs:subClassOf obo:VO_0005493 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0020814 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Pentacel]" ;
  rdfs:subClassOf obo:VO_0000084 , obo:VO_0020832 .

obo:VO_0007453 a rdfs:Class ;
  rdfs:label "human papillomavirus vaccine V503" ;
  rdfs:comment "A vaccine consisting of noninfectious, recombinant virus-like particles (VLP) containing the major viral capsid protein L1 of nine strains of human papillomavirus (HPV), with potential immunoprotective activity. Vaccination with HPV V503 may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against cells positive for any of these nine strains of HPV, thereby preventing cervical infection upon exposure to certain HPV subtypes." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000667 , obo:VO_0007656 .

obo:OGG_3000885594 a rdfs:Class ;
  rdfs:label "secA2" ;
  rdfs:comment "Possible preprotein translocase ATPase SecA2" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0010282 a rdfs:Class ;
  rdfs:label "vaccine target datum" ;
  rdfs:comment "A measurment datum that records the intended target of a vaccine." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0002996 a rdfs:Class ;
  rdfs:label "VEE Virus PE2/E1 mutant vaccine" ;
  rdfs:comment "A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE" ;
  rdfs:subClassOf obo:VO_0001499 .

obo:VO_0020954 a rdfs:Class ;
  rdfs:label "influenza B virus antigen 160000000 /ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010301 , obo:VO_0010415 .

obo:VO_0000729 a rdfs:Class ;
  rdfs:label "Herpes simplex virus vaccine" ;
  rdfs:subClassOf obo:VO_0000727 .

obo:VO_0018701 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 TCID [RUDIVAX]" ;
  rdfs:subClassOf obo:VO_0003112 , obo:VO_0018700 .

obo:VO_0004642 a rdfs:Class ;
  rdfs:label "CAdVax-RVFV glycoprotein vaccine" ;
  rdfs:subClassOf obo:VO_0012166 .

obo:IAO_8000006 a rdfs:Class ;
  rdfs:label "subset ontology module"@en ;
  rdfs:comment "An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/filter> , <http://www.geneontology.org/page/go-slim-and-subset-guide> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:VO_0016286 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0016026 .

obo:VO_0019679 a rdfs:Class ;
  rdfs:label "Bordetella pertussis as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0018233 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018252 .

obo:VO_0015489 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0010264 a rdfs:Class ;
  rdfs:label "host disease state datum" ;
  rdfs:comment "A measurement datum that records the presence of a disease process in a host during the implementation of a vaccine study." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0003613 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML [Fluzone Quadrivalent 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003611 .

obo:VO_0007724 a rdfs:Class ;
  rdfs:label "personalized mature dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine that may stimulate the immune system to react to lung cancer cells, in combination with Cyclophosphamide." ;
  rdfs:subClassOf obo:VO_0005486 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0002850 a rdfs:Class ;
  rdfs:label "Francisella tularensis purF mutant vaccine" ;
  rdfs:comment "Mice, which had been immunized with at least 6.95x103 cfu of F. tularensis U112 purF::Cm, were protected against the subsequent F. tularensis subspecies novicida challenge." ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0017398 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adt Vaccine]" ;
  rdfs:subClassOf obo:VO_0017384 , obo:VO_0017395 .

obo:VO_0003946 a rdfs:Class ;
  rdfs:label "CERVARIX Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003944 .

obo:VO_0004468 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine sC encoding prM and E" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0017903 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.3 MG/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017845 , obo:VO_0017929 .

obo:NCBITaxon_10788 a rdfs:Class ;
  rdfs:label "Canine parvovirus" ;
  rdfs:subClassOf obo:NCBITaxon_3052707 .

obo:CL_0000763 a rdfs:Class ;
  rdfs:label "myeloid cell" ;
  rdfs:comment "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." ;
  rdfs:subClassOf obo:CL_0000255 , obo:CL_0000988 .

obo:VO_0003914 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/9/2014 antigen" ;
  rdfs:comment "CUI: C4059934" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:VO_0004926 a rdfs:Class ;
  rdfs:label "age range at vaccination" ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0017992 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018033 .

obo:VO_0020462 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1 by Waymade" ;
  rdfs:subClassOf obo:VO_0020444 .

obo:VO_0001102 a rdfs:Class ;
  rdfs:label "retroviral vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a retroviral strain" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0018108 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 20000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution [Priorix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018107 .

obo:VO_0017052 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017051 .

obo:VO_0004428 a rdfs:Class ;
  rdfs:label "Colorectal cancer DNA vaccine pCEA/HBsAg encoding carcinoembryonic antigen and hepatitis B surface antigen" ;
  rdfs:comment "CEA" ;
  rdfs:subClassOf obo:VO_0005489 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0005069 a rdfs:Class ;
  rdfs:label "pGFP DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pGFP.  This plasmid is 3300 base pairs in length and contains a lac promoter and an ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003154 a rdfs:Class ;
  rdfs:label "ISS 1018 CpG ODN vaccine adjuvant" ;
  rdfs:comment "A CpG DNA vaccine adjuvant that is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity." ;
  rdfs:subClassOf obo:VO_0001237 .

obo:VO_0017073 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017555 .

obo:VO_0004733 a rdfs:Class ;
  rdfs:label "ALVAC-NiV-G vaccine" ;
  rdfs:subClassOf obo:VO_0012169 .

obo:VO_0016573 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Ambirix]" ;
  rdfs:subClassOf obo:VO_0016580 .

obo:VO_0010310 a rdfs:Class ;
  rdfs:label "influenza B virus B/Hong Kong/259/2010 antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003519 , obo:VO_0010301 .

obo:VO_0019799 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003898 .

obo:VO_0001785 a rdfs:Class ;
  rdfs:label "Avian Polyomavirus Killed Virus Vaccine (USDA: 1A15.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0000712 , obo:VO_0001473 , obo:VO_0001492 , obo:VO_0007748 .

obo:VO_0000515 a rdfs:Class ;
  rdfs:label "rough phenotype" ;
  rdfs:subClassOf obo:VO_0000549 .

obo:VO_0004709 a rdfs:Class ;
  rdfs:label "rvOka-HN mumps virus vaccine" ;
  rdfs:subClassOf obo:VO_0000656 .

obo:VO_0002395 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine" ;
  rdfs:subClassOf obo:VO_0002393 , obo:VO_0002408 .

obo:VO_0018339 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT Injection [Imovax] by Sanofi" ;
  rdfs:subClassOf obo:VO_0018300 .

obo:VO_0000791 a rdfs:Class ;
  rdfs:label "human gene" ;
  rdfs:subClassOf obo:OGG_0000000002 .

obo:VO_0003672 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML [PedvaxHIB]" ;
  rdfs:subClassOf obo:VO_0000083 .

obo:VO_0021009 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 19400 PFU Injection" ;
  rdfs:subClassOf obo:VO_0021007 .

obo:VO_0017552 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML [Revaxis]" ;
  rdfs:subClassOf obo:VO_0017548 .

obo:VO_0006070 a rdfs:Class ;
  rdfs:label "SARS-COV-2 COVID-19 Non-US Vaccine Specific Product Unknown" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005264 .

obo:VO_0003431 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0000364 a rdfs:Class ;
  rdfs:label "pRK7 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0017415 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0018795 .

obo:VO_0016037 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 20" ;
  rdfs:subClassOf obo:VO_0003422 .

obo:VO_0020573 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Influsplit]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020869 .

obo:VO_0017479 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0017476 .

obo:VO_0001616 a rdfs:Class ;
  rdfs:label "Bronchitis Delaware Type, Modified Live Virus Vaccine (USDA: 1231.1D)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0000849 a rdfs:Class ;
  rdfs:label "Improvac vaccine" ;
  rdfs:comment "A vaccine that stimulates the pig's own immune system to produce specific antibodies against GnRF. This temporarily inhibits testes function and thus stops the production and accumulation of boar taint-causing compounds." ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000759 .

obo:VO_0007188 a rdfs:Class ;
  rdfs:label "obsolete 12 Melanoma Peptide Vaccine" .

obo:VO_0020933 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020929 .

obo:VO_0001914 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4141.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002346 .

obo:VO_0004512 a rdfs:Class ;
  rdfs:label "Chinese Schistosoma japonicum DNA vaccine SjC23" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001229 .

obo:VO_0015559 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015555 .

obo:VO_0010963 a rdfs:Class ;
  rdfs:label "RpsL" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0003555 a rdfs:Class ;
  rdfs:label "Bacilli vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003554 .

obo:VO_0010436 a rdfs:Class ;
  rdfs:label "licensed human clostridium tetani vaccine" ;
  rdfs:comment "Clostridium tetani vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000640 .

obo:VO_0001573 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Modified Live Virus Vaccine (USDA: 1201.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0001501 .

obo:VO_0000554 a rdfs:Class ;
  rdfs:label "human vaccinee at age 2-17 years old" ;
  rdfs:subClassOf obo:VO_0000544 .

obo:OBI_0000272 a rdfs:Class ;
  rdfs:label "protocol"@en ;
  rdfs:comment "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:VO_0021151 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML / mumps virus vaccine live, Jeryl Lynn strain 40000 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML / varicella-zoster virus vaccine live (Oka-Merck) strain 20000 UNT/ML Injection [ProQuad]" ;
  rdfs:subClassOf obo:VO_0003577 .

obo:VO_0019231 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0002705 a rdfs:Class ;
  rdfs:label "gE from Equid herpesvirus" ;
  rdfs:comment "A glycoprotein E mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001431 .

obo:VO_0019390 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [Tripedia]" ;
  rdfs:subClassOf obo:VO_0000112 , obo:VO_0017799 , obo:VO_0018770 .

obo:VO_0004417 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine LF pDNA encoding LF" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0002772 a rdfs:Class ;
  rdfs:label "obsolete Actinobacillus pleuropneumoniae apxIIIB and apxIIID double mutant vaccine" ;
  rdfs:comment "An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain" .

obo:OPL_0000158 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum schizont stage" ;
  rdfs:comment "A schizont stage in the Plasmodium falciparum lifecycle that occurs in erythrocytes or in hepatocytes." ;
  rdfs:subClassOf obo:OPL_0000084 , obo:OPL_0000165 , obo:OPL_0000297 .

obo:VO_0004072 a rdfs:Class ;
  rdfs:label "Ebola virus recombinant adenovirus vector vaccine ADV-GP/NP" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000726 .

obo:VO_0017581 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0017555 .

obo:VO_0011356 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae ApxIA protein vaccine" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0001834 a rdfs:Class ;
  rdfs:label "Mink Distemper-Enteritis Modified Live & Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 4949.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0002450 , obo:VO_0007748 , obo:VO_0010475 .

obo:VO_0003338 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0017880 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.005 MG" ;
  rdfs:subClassOf obo:VO_0015069 .

obo:VO_0005506 a rdfs:Class ;
  rdfs:label "canvaxgen" ;
  rdfs:comment "Gene expressing a protein which serves, either in whole or in part, as an antigen within a cancer vaccine." ;
  rdfs:subClassOf obo:OGG_0000000002 .

obo:VO_0002792 a rdfs:Class ;
  rdfs:label "Trichinella spiralis vaccine" ;
  rdfs:comment "A protozoan vaccine against Trichinella spiralis infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:NCBITaxon_9443 a rdfs:Class ;
  rdfs:label "Primates" ;
  rdfs:subClassOf obo:NCBITaxon_314146 .

obo:NCBITaxon_1773 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis" ;
  rdfs:subClassOf obo:NCBITaxon_1763 .

obo:VO_0019810 a rdfs:Class ;
  rdfs:label "influenza A virus A/Indonesia/05/2005 (H5N1) antigen 0.0075 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018850 .

obo:VO_0016985 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 160 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution [T Polio Adsorbed]" ;
  rdfs:subClassOf obo:VO_0016984 , obo:VO_0017461 .

obo:VO_0007183 a rdfs:Class ;
  rdfs:label "RCAS-Ras Vaccine" ;
  rdfs:comment "A recombinant retroviral virus derived from SR-A strain of Rous sarcoma virus carrying a human gene encoding the G12D mutant form of K-Ras. The viral vector, RCAS harbors a Replication Competent ALV Splice acceptor. This recombinant virus was use in animal model to study gliomagenesis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0002472 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome-Circovirus Vaccine-Mycoplasma Hyopneumoniae Bacterin" ;
  rdfs:subClassOf obo:VO_0002467 .

obo:VO_0010196 a rdfs:Class ;
  rdfs:label "Influenza, adjuvanted, inactivated, quadrivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0010415 .

obo:VO_0020648 a rdfs:Class ;
  rdfs:label "1 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution [Varilrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0020647 , obo:VO_0021015 .

obo:VO_0003957 a rdfs:Class ;
  rdfs:label "Vaxchora Oral Product" ;
  rdfs:subClassOf obo:VO_0003082 .

obo:NCBITaxon_2093 a rdfs:Class ;
  rdfs:label "Mycoplasma" ;
  rdfs:subClassOf obo:NCBITaxon_544448 .

obo:VO_0007505 a rdfs:Class ;
  rdfs:label "MART-1/gp100/Tyrosinase/MAGE-A3 peptides-loaded irradiated allogeneic plasmacytoid dendritic cells vaccine" ;
  rdfs:comment "Irradiated allogeneic, HLA-A*0201 positive, plasmacytoid dendritic cells (pDCs) loaded with 4 melanoma peptides derived from the tumor associated antigens (TAAs) MelA/MART-1, gp100/pmel17, tyrosinase, and MAGE-A3, with potential immunostimulating and antineoplastic activities. Upon subcutaneous administration, the irradiated allogeneic pDCs may trigger functional multi-specific T cells from peripheral blood mononuclear cells and tumor-infiltrating lymphocytes, and activate the immune system to mount a cytotoxic T-lymphocyte response against HLA-A*0201 positive melanoma cancer cells expressing the TAAs MelA/MART-1, gp100/pmel17, tyrosinase, and MAGE-A3. These TAAs are upregulated in a variety of tumor cells. The pDCs are derived from a distinct subset of dendritic cells (DCs) with a plasma cell-like morphology and express a characteristic set of surface markers and may increase the anti-tumor immune responses." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0015968 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 10" ;
  rdfs:subClassOf obo:VO_0003265 .

obo:VO_0000239 a rdfs:Class ;
  rdfs:label "vaccine-induced down-regulated gene expression" ;
  rdfs:subClassOf obo:VO_0000286 .

obo:OBI_0000458 a rdfs:Class ;
  rdfs:label "manufacturing objective"@en ;
  rdfs:comment "is the objective to manufacture a material of a certain function (device)"@en ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:VO_0018122 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella virus vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0011364 a rdfs:Class ;
  rdfs:label "cancer DNA vaccine MIDGE/hNIS encoding hNIS protein" ;
  rdfs:comment "Gene name: SLC5A5" ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0000988 a rdfs:Class ;
  rdfs:label "Theileria parva vaccine by local veterinary institutes" ;
  rdfs:subClassOf obo:VO_0001061 , obo:VO_0001466 .

obo:VO_0010204 a rdfs:Class ;
  rdfs:label "meningococcal Groups C and Y and Haemophilus b Tetanus Toxoid Conjugate Vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010437 , obo:VO_0010444 .

obo:VO_0010758 a rdfs:Class ;
  rdfs:label "Brucella protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:OPL_0000273 a rdfs:Class ;
  rdfs:label "Plasmodium oocyst" ;
  rdfs:comment "A Plasmodium that is formed after traversal of the midgut wall by the ookinete stage, on the hemocoel side of the midgut wall of the mosquito vector." ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0007568 a rdfs:Class ;
  rdfs:label "liposomal MUC1/PET-lipid A vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a 43 amino acid epitope from glycoprotein MUC1 (mucin 1) and the synthetic Toll-like receptor 4 (TLR-4) agonist PET lipid A encapsulated in cholesterol/dipalmitoylphosphatidylcholine (DPPC)/dimyristoylphosphatidylglycerol (DMPG) liposomes, with potential immunostimulatory and antineoplastic activities. The MUC1 epitope is composed of two 20 amino glycosylated VNTR (various number tandem repeats) from human MUC1A and including 6 glycosylated sites modified by Tn (alfa-N-acetyl-D-galactosamine). Immunization of liposomal MUC1/PET-lipid A vaccine results in an antibody as well as a cytotoxic T-lymphocyte (CTL) response against hypoglycosylated MUC1 expressing tumor cells. The tumor associated antigen MUC1, a type I transmembrane protein, is overexpressed and aberrantly glycosylated in a variety of tumor cells. As a vaccine adjuvant, PET lipid A, also known as penta erythritol lipid A, stimulates both cellular and humoral responses to the vaccine antigen." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0001247 a rdfs:Class ;
  rdfs:label "Arepanrix H1N1 vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0010415 .

obo:VO_0001815 a rdfs:Class ;
  rdfs:label "West Nile Virus Live Flavivirus Chimera Vaccine (USDA: 1991.R1)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000752 , obo:VO_0001220 , obo:VO_0001475 , obo:VO_0007748 .

obo:VO_0003496 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, Inactivated A-Christchurch-16-2010 NIB-74 (H1N1) (A-California-7-2009) strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0001674 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.13)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001488 , obo:VO_0007748 .

obo:VO_0019784 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010433 .

obo:VO_0016247 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015915 .

obo:VO_0018064 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018053 .

obo:VO_0010055 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum RH5" ;
  rdfs:comment "A RH5 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0003384 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001214 , obo:VO_0003396 , obo:VO_0010436 .

obo:OPL_0000282 a rdfs:Class ;
  rdfs:label "Plasmodium erythrocytic trophozoite" ;
  rdfs:comment "A Plasmodium trophozoite that is found in erythrocytes of a vertebrate host." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000281 .

obo:VO_0016502 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:VO_0004056 a rdfs:Class ;
  rdfs:label "Streptococcus pyogenes SfbI protein vaccine" ;
  rdfs:subClassOf obo:VO_0002852 .

obo:VO_0003933 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 16 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 6 Vaccine 0.04 MG/ML [Gardasil]" ;
  rdfs:subClassOf obo:VO_0000049 .

obo:VO_0003652 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2018-2019 vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003650 .

obo:NCBITaxon_2732514 a rdfs:Class ;
  rdfs:label "Revtraviricetes" ;
  rdfs:subClassOf obo:NCBITaxon_2559587 .

obo:VO_0005446 a rdfs:Class ;
  rdfs:label "licensed human immune globulin passive vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0005439 .

obo:VO_0020879 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] Box of 50" ;
  rdfs:subClassOf obo:VO_0020876 , obo:VO_0020886 .

obo:VO_0018222 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0018220 , obo:VO_0018221 .

obo:VO_0003280 a rdfs:Class ;
  rdfs:label "obsolete 0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Injection" .

obo:VO_0002496 a rdfs:Class ;
  rdfs:label "influenza vaccine (surface antigens, inactivated)" ;
  rdfs:comment """created according to 
WHO Technical Report Series, No. 927, 2005
Annex 3
Recommendations for the production and control of influenza vaccine (inactivated)""" ;
  rdfs:subClassOf obo:VO_0001176 .

obo:VO_0020454 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0019351 , obo:VO_0020430 .

obo:VO_0010984 a rdfs:Class ;
  rdfs:label "Hma" ;
  rdfs:comment "A vaccine made by Hma from E. coli strain CFT073 and 536 induced protection to the infection of virulent  strain CFT073 and 536,  respectively, in the bladder in the CBA/J mice.  [PubMed: 19806177]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0017400 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 25 LFU/ML / Pertussis Vaccine 8 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML [Tri-Immunol Im]" ;
  rdfs:subClassOf obo:VO_0018792 .

obo:VO_0019900 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Afluria 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020302 .

obo:VO_0003056 a rdfs:Class ;
  rdfs:label "obsolete viral haemorrhagic septicaemia virus vaccine" ;
  rdfs:comment "A viral vaccine against infection of a viral haemorrhagic septicaemia virus." .

obo:DOID_0060119 a rdfs:Class ;
  rdfs:label "pharynx cancer"@en ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the pharynx."@en ;
  rdfs:subClassOf obo:DOID_3119 .

obo:VO_0018522 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0007053 a rdfs:Class ;
  rdfs:label "Vaccinia virus DD-CDSR vaccine" ;
  rdfs:comment "A highly tumor-selective vaccinia virus (vv) with an engineered double deletion (DD) of the thymidine kinase (tk) and vaccinia growth factor genes and additions of both a cytosine deaminase (CD) gene and a somatostatin receptor (SR) gene with potential oncolytic viral activity. The tk and vaccinia growth factor gene deletions in intratumorally administered vaccinia virus (vvDD-CDSR) help to restrict its replication and cytolytic activity to tumor cells with large nucleotide pools and tumor cells with activation of the EGFR-Ras pathway. Addition of the CD gene to the viral genome allows control of oncolytic viral infection through the administration of the prodrug 5-fluorocytosine (5-FC), converted by CD to the antimetabolite 5-fluorouracil (5-FU) in cells infected with this agent. Addition of the SR gene allows anatomical localization of vaccinia virus (vvDD-CDSR) through the use of octreotide scintigraphy." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0004744 a rdfs:Class ;
  rdfs:label "rFPV-ILTV vaccine" ;
  rdfs:subClassOf obo:VO_0001488 .

obo:VO_0000785 a rdfs:Class ;
  rdfs:label "DNA vaccine expressing sGP" ;
  rdfs:comment "A DNA vaccine that encodes for a secreted form of Ebola virus GP protein." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000726 .

obo:VO_0000583 a rdfs:Class ;
  rdfs:label "nontypeable H. influenzae gene hel (encoding P4)" ;
  rdfs:subClassOf obo:VO_0000581 , obo:VO_0001232 .

obo:VO_0004352 a rdfs:Class ;
  rdfs:label "Hepatitis B DNA vaccine PLGA-CTAB-DNA encoding the small envelope gene" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000644 .

obo:VO_0002543 a rdfs:Class ;
  rdfs:label "secA2 from Mycobacterium tuberculosis" ;
  rdfs:comment "Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Gu√©rin vaccination" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0005172 a rdfs:Class ;
  rdfs:label "INO-4800 vaccine" ;
  rdfs:comment "A DNA vaccine that expresses S protein from the pGX9501 vector" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0016890 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.2 LFU/ML Injectable Solution Box of 5 by Aventis" ;
  rdfs:subClassOf obo:VO_0016835 .

obo:VO_0002398 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus vaccine-Borrelia Burgdorferi Bacterin" ;
  rdfs:subClassOf obo:VO_0001490 , obo:VO_0001526 , obo:VO_0002392 , obo:VO_0002393 , obo:VO_0012178 .

obo:VO_0004457 a rdfs:Class ;
  rdfs:label "Chinese Schistosoma japonicum DNA vaccine pVAX/SjFABP encoding FABP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001229 .

obo:VO_0001793 a rdfs:Class ;
  rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.04)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001456 , obo:VO_0007748 .

obo:VO_0002816 a rdfs:Class ;
  rdfs:label "obsolete B. melitensis omp25 mutant vaccine" ;
  rdfs:comment "A omp25 mutant is attenuated and provides protection against challenge in mice" .

obo:VO_0019744 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020346 .

obo:VO_0016444 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0010780 a rdfs:Class ;
  rdfs:label "Hepatitis A virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0020231 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain 100000000 UNT/ML [Dryvax]" ;
  rdfs:subClassOf obo:VO_0020230 .

obo:VO_0017592 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017682 .

obo:NCBITaxon_236 a rdfs:Class ;
  rdfs:label "Brucella ovis" ;
  rdfs:subClassOf obo:NCBITaxon_234 .

obo:VO_0015873 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015615 , obo:VO_0015695 , obo:VO_0015998 .

obo:VO_0019359 a rdfs:Class ;
  rdfs:label "0.7 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:DOID_1789 a rdfs:Class ;
  rdfs:label "benign peritoneal mesothelioma"@en ;
  rdfs:subClassOf obo:DOID_0060097 .

obo:VO_0016404 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 3 by Mtk" ;
  rdfs:subClassOf obo:VO_0015960 , obo:VO_0015966 .

obo:VO_0007647 a rdfs:Class ;
  rdfs:label "Oral Bacille Calmette-Guerin for malignant melanoma vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020161 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0017673 .

obo:VO_0020767 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG Injectable Suspension [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020759 , obo:VO_0020766 , obo:VO_0020807 .

obo:OBI_0000673 a rdfs:Class ;
  rdfs:label "statistical hypothesis test"@en ;
  rdfs:comment "A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:VO_0019298 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluvirin 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020477 .

obo:VO_0011275 a rdfs:Class ;
  rdfs:label "Cpa" ;
  rdfs:comment "Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge with L. major.  Mice inoculated pCMV3ISS-CPa developed significantly smaller lesions in their footpads after challenge with the parasite.  The vaccine was able to induce a partially protective effect [PubMed: 18951941]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0011126 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Yamagata/120/1986(H1N1))" ;
  rdfs:comment "The inoculation of HA vaccine prepared from influenza viruses A/Yamagata/120/86 (H1N1) or A/Fukuoka/C29/85 (H3N2) together with CTB provided partial protection against PR-8 infection in Balb/c mice [PubMed: 2781859]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0016716 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0016679 , obo:VO_0016685 , obo:VO_0016721 .

obo:VO_0007541 a rdfs:Class ;
  rdfs:label "hTERT I540/R572Y/D988Y multipeptide vaccine" ;
  rdfs:comment "A peptide vaccine consisting of multiple epitopes derived from the human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, with potential immunostimulating and antineoplastic activities. hTERT I540/R572Y/D988Y multipeptide vaccine contains strongly antigenic peptide epitopes I540 (9-mer), R572Y (9-mer) and D988Y (10-mer). Vaccination with this agent may elicit a cytotoxic T cell (CTL) response against telomerase-expressing tumor cells. Directly linked to tumorigenesis, telomerase is expressed in the majority of human cancer cells but is infrequently expressed in normal cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005427 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0019483 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0003408 , obo:VO_0010437 .

obo:NCBITaxon_5661 a rdfs:Class ;
  rdfs:label "Leishmania donovani" ;
  rdfs:subClassOf obo:NCBITaxon_38574 .

obo:VO_0004695 a rdfs:Class ;
  rdfs:label "PAV3-HA (H5N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0001343 a rdfs:Class ;
  rdfs:label "immunoliposomes containing antibodies to costimulatory molecules" ;
  rdfs:comment "A liposome-based vaccine adjuvant which is prepared from dehydration-rehydration vesicles (DRVs)." ;
  rdfs:subClassOf obo:VO_0000366 .

obo:VO_0011464 a rdfs:Class ;
  rdfs:label "Canine parvovirus CPMV-PARVO1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012180 .

obo:VO_0005198 a rdfs:Class ;
  rdfs:label "COVID-19 RNA vaccine" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0004908 .

obo:VO_0016996 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [T Immun]" ;
  rdfs:subClassOf obo:VO_0016995 , obo:VO_0017484 .

obo:VO_0011087 a rdfs:Class ;
  rdfs:label "SNVsSgp1" ;
  rdfs:comment "Study used a deer mouse infection model to test the protective efficacy of genetic vaccine candidates for Sin Nombre (SN) virus that were known to provoke immunological responses in BALB/c mice. Protective epitopes were localized in each of four overlapping cDNA fragments that encoded portions of the SN virus G1 glycoprotein antigen; the nucleocapsid gene (SNVsSgp1) also was protective [PubMed: 12075094]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010768 .

obo:VO_0018780 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010447 .

obo:DOID_0050686 a rdfs:Class ;
  rdfs:label "organ system cancer"@en ;
  rdfs:comment "A cancer that is classified based on the organ it starts in."@en ;
  rdfs:subClassOf obo:DOID_162 .

obo:VO_0000483 a rdfs:Class ;
  rdfs:label "protein subunit vaccine" ;
  rdfs:comment "A subunit vaccine that is made using a part of whole organism as subunit for vaccine development. " ;
  rdfs:subClassOf obo:VO_0000534 .

obo:VO_0005513 a rdfs:Class ;
  rdfs:label "ME-F-1122 vaccine adjuvant" ;
  rdfs:comment "Liposome-based vaccine adjuvant with TLR4 agonist to induce a mixed Th1/Th2 response." ;
  rdfs:subClassOf obo:VO_0000366 .

obo:NCBITaxon_3052342 a rdfs:Class ;
  rdfs:label "Morbillivirus canis" ;
  rdfs:subClassOf obo:NCBITaxon_11229 .

obo:VO_0007019 a rdfs:Class ;
  rdfs:label "Sialyl Tn-KLH Vaccine" ;
  rdfs:comment "A vaccine containing a pancarcinoma carbohydrate antigen conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Sialylated Tn antigen (sTn) is a monosaccharide glycan usually O-linked to serine or threonine residues of mucins found on most epithelial cancers. Conjugation with KLH, a hapten carrier and an immunostimulant, improves host immune responses. Vaccination with sTn-KLH vaccine may produce antibodies and elicit a cytotoxic T lymphocyte (CTL) response against those tumor cells expressing sTn, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0012162 a rdfs:Class ;
  rdfs:label "Marek's disease virus vaccine" ;
  rdfs:comment "A vaccine that protects against Marek's disease virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000727 .

obo:VO_0010241 a rdfs:Class ;
  rdfs:label "assay mesurement variable" ;
  rdfs:comment "A variable representing the measurement used for an assay" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:DOID_263 a rdfs:Class ;
  rdfs:label "kidney cancer"@en ;
  rdfs:comment "A urinary system cancer that is located_in the kidney."@en ;
  rdfs:subClassOf obo:DOID_3996 .

obo:VO_0019364 a rdfs:Class ;
  rdfs:label "1 ML hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019508 .

obo:VO_0005363 a rdfs:Class ;
  rdfs:label "Montanide ISA 50 vaccine adjuvant" ;
  rdfs:comment "A Montanide vaccine adjuvant that Mannide oleate derivative in a mineral oil solution ( Seppic SA, France)." ;
  rdfs:subClassOf obo:VO_0001271 .

obo:VO_0019769 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML [Afluria Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0020304 .

obo:VO_0017401 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 25 LFU/ML / Pertussis Vaccine 8 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017349 .

obo:VO_0020250 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.008 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0010210 , obo:VO_0010445 .

obo:IDO_0000409 a rdfs:Class ;
  rdfs:label "definitive host role"@en ;
  rdfs:comment "A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis reaches developmental maturity or reproduces sexually in the host.  "@en ;
  rdfs:subClassOf obo:OBI_0000725 .

obo:VO_0015027 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Tenivac]" ;
  rdfs:subClassOf obo:VO_0000102 .

obo:VO_0016451 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0017424 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection Box of 5" ;
  rdfs:subClassOf obo:VO_0017420 .

obo:VO_0010115 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii ROP38" ;
  rdfs:comment "A ROP38 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0018537 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 12 BAU/ML Injectable Suspension [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0018536 , obo:VO_0018634 .

obo:VO_0007469 a rdfs:Class ;
  rdfs:label "Interleukin-2 Anti-Idiotype Vaccine" ;
  rdfs:comment "A vaccine based on anti-idiotype (Id) monoclonal antibodies combined with interleukin-2 (IL-2). Anti-Id vaccines have been shown to be effective in treatment of B-cell lymphoma in animal models and in clinical trials, resulting in tumor regression; the addition of interleukin-2 (IL-2) may augment the therapeutic effect of anti-Id vaccines." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0007620 a rdfs:Class ;
  rdfs:label "IFN/tremem vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0004551 a rdfs:Class ;
  rdfs:label "Foot-and-Mouth Disease Virus DNA vaccine pSinCMV-Vac-MEG990" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001213 .

obo:VO_0004621 a rdfs:Class ;
  rdfs:label "vNDV-H5 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0016186 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:VO_0020414 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0020389 , obo:VO_0020400 .

obo:NCBITaxon_56690 a rdfs:Class ;
  rdfs:label "Tritrichomonas suis" ;
  rdfs:subClassOf obo:NCBITaxon_2611341 .

obo:VO_0004312 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine pSAG1-ROP2-SAG2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:VO_0004839 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0000736 a rdfs:Class ;
  rdfs:label "Measles-Mumps vaccine" ;
  rdfs:comment "A Measles virus vaccine that also protects against infection with  Mumps virus." ;
  rdfs:subClassOf obo:VO_0000654 , obo:VO_0000656 .

obo:VO_0021026 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 PFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0021024 , obo:VO_0021044 .

obo:VO_0007212 a rdfs:Class ;
  rdfs:label "AE37 Peptide/GM-CSF Vaccine" ;
  rdfs:comment "A vaccine containing HER2/Neu-derived epitope (amino acids 776-790) linked to li-Key peptide (li-Key/HER2/neu hybrid peptide or AE37), and combined with granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential antineoplastic and immunoadjuvant activities. Upon vaccination, AE37 may activate the immune system and stimulate T-helper cells against HER2/Neu expressing cancer cells. GM-CSF may potentiate the immune response against cancer cells expressing the HER2/Neu antigen. The Ii-Key moiety, a 4-amino acid (LRMK) epitope from the MHC class II-associated invariant chain (Ii protein), increases T-helper cell stimulation against HER2/neu antigen when compared to unmodified class II epitopes. HER2/neu, a tumor associated antigen (TAA), is overexpressed in a variety of tumor cell types and is highly immunogenic." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0001207 a rdfs:Class ;
  rdfs:label "Chlamydia trachomatis vaccine" ;
  rdfs:comment "A Chlamydia bacterial vaccine against Chlamydia trachomatis infection" ;
  rdfs:subClassOf obo:VO_0000573 .

obo:VO_0010226 a rdfs:Class ;
  rdfs:label "yellow fever vaccine live" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010456 .

obo:VO_0002333 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae- Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002334 .

obo:VO_0011054 a rdfs:Class ;
  rdfs:label "VP2 from Canine parvovirus" ;
  rdfs:comment "A vaccine based upon a recombinant plant virus (CPMV-PARVO1), displaying a peptide derived from the VP2 capsid protein of canine parvovirus (CPV), has previously been described. To date, studies with the vaccine have utilized viable plant chimaeric particles (CVPs).  Results show that the inactivated CVP is able to protect dogs from a lethal challenge with CPV following parenteral immunization with the vaccine.  Dogs immunized with the inactivated CPMV-PARVO1 in adjuvant displayed no clinical signs of disease and shedding of CPV in faeces was limited following CPV challenge. [PubMed: 11395200]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010807 .

obo:VO_0015072 a rdfs:Class ;
  rdfs:label "injectable suspension" ;
  rdfs:subClassOf obo:VO_0015062 .

obo:VO_0004375 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine encoding ASP-2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0016122 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015877 .

obo:VO_0015103 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015094 , obo:VO_0015259 .

obo:VO_0010076 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi Tc80" ;
  rdfs:comment "A Tc80 protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0007589 a rdfs:Class ;
  rdfs:label "obsolete Bcl-Xs Adenovirus Vaccine" .

obo:VO_0017051 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] Box of 10" ;
  rdfs:subClassOf obo:VO_0017050 , obo:VO_0017058 , obo:VO_0017523 .

obo:VO_0002309 a rdfs:Class ;
  rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49F6.22)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002464 , obo:VO_0007748 .

obo:VO_0017481 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML [Tet Aktiv]" ;
  rdfs:subClassOf obo:VO_0017684 .

obo:VO_0001236 a rdfs:Class ;
  rdfs:label "trivalent influenza vaccine" ;
  rdfs:subClassOf obo:VO_0003495 .

obo:VO_0018541 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection [Cervarix] Box of 10" ;
  rdfs:subClassOf obo:VO_0018540 , obo:VO_0018543 .

obo:VO_0017432 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0017672 .

obo:VO_0018270 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003862 .

obo:VO_0000856 a rdfs:Class ;
  rdfs:label "cell culture residual in vaccine" ;
  rdfs:comment "a vaccine residual that is generatead from cell culture for vaccine preparation. Examples include: antibiotics, sensitizing substances, bacterial and cellular residuals, and adventitious agents." ;
  rdfs:subClassOf obo:VO_0000854 .

obo:VO_0015787 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0015490 .

obo:VO_0019147 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0017186 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017629 .

obo:VO_0018548 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML Injectable Suspension [Cervarix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018547 .

obo:VO_0002823 a rdfs:Class ;
  rdfs:label "arthritis vaccine" ;
  rdfs:comment "A vaccine that prevents or treats arthritis." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005503 .

obo:VO_0010368 a rdfs:Class ;
  rdfs:label "Fluzone High-Dose Quadrivalent Southern Hemisphere vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0000763 a rdfs:Class ;
  rdfs:label "Vibrio cholerae vaccine" ;
  rdfs:comment "A bacterial vaccine that prevents infection with Vibrio cholera." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000566 .

obo:VO_0020081 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003499 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0005404 a rdfs:Class ;
  rdfs:label "VXS-1223 vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Vaxxas Pty Ltd" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0003865 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML [RabAvert]" ;
  rdfs:subClassOf obo:VO_0000094 .

obo:VO_0020677 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0020032 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe [Fluarix 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020028 , obo:VO_0020314 .

obo:VO_0016564 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0016559 .

obo:VO_0016777 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0016721 .

obo:VO_0004050 a rdfs:Class ;
  rdfs:label "Streptococcus agalactiae BPS protein vaccine" ;
  rdfs:subClassOf obo:VO_0001375 .

obo:VO_0019627 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flulaval Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020345 .

obo:VO_0018761 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003372 , obo:VO_0018809 .

obo:VO_0003667 a rdfs:Class ;
  rdfs:label "YF-VAX 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003666 .

obo:VO_0001753 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine (USDA: 18P5.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012180 .

obo:VO_0020834 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b 0.04 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020836 .

obo:VO_0017564 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] Box of 10" ;
  rdfs:subClassOf obo:VO_0017563 , obo:VO_0017576 .

obo:NCBITaxon_6183 a rdfs:Class ;
  rdfs:label "Schistosoma mansoni" ;
  rdfs:subClassOf obo:NCBITaxon_6181 .

obo:VO_0011139 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/chicken/Guangdong/02/2007(H9N2))" ;
  rdfs:comment "Using reverse genetics, we constructed a recombinant NDV expressing an H9 AIV hemagglutinin (HA) from an H9N2 field isolate, A/Chicken/ Shandong/2/2007.  When tested, 90% of chickens were protected from clinical disease, mortality, and virus shedding against challenge with homologous H9N2 AIV [PubMed: 20521648]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0005484 a rdfs:Class ;
  rdfs:label "breast cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against breast cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0016524 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0018309 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0018283 .

obo:NCBITaxon_1386 a rdfs:Class ;
  rdfs:label "Bacillus <firmicutes>" ;
  rdfs:subClassOf obo:NCBITaxon_1385 .

obo:VO_0011177 a rdfs:Class ;
  rdfs:label "E protein from West Nile virus" ;
  rdfs:comment "The immunogenicity and protective efficacy of a recombinant subunit West Nile virus (WNV) vaccine was evaluated in rhesus macaques (Macaca mulatta). The vaccine consisted of a recombinant envelope (E) protein truncated at the C-terminal end, resulting in a polypeptide containing 80% of the N-terminal amino acids of the native WNV protein (WN-80E), mixed with an adjuvant (GPI-0100). Groups of monkeys were immunized with the WN-80E/GPI-0100 vaccine or an adjuvant-only control formulation. Animals were then challenged by inoculation of wild-type WNV, and the level of viremia in each animal was monitored daily for 10 days. The results showed that whereas all animals in the control group had detectable viremia for at least 3 days after challenge, all of the vaccinated animals were negative on all days after challenge. Thus, the WN-80E vaccine was 100% efficacious in protecting monkeys against infection with WNV [PubMed: 19641099]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010803 .

obo:VO_0004446 a rdfs:Class ;
  rdfs:label "Prostate cancer DNA vaccine hPSMAt encoding PSMA" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0016372 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 20 by Merck" ;
  rdfs:subClassOf obo:VO_0016037 .

obo:VO_0020321 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2020-2021 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0000983 , obo:VO_0010424 .

obo:VO_0021157 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0016599 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Adult] Box of 1" ;
  rdfs:subClassOf obo:VO_0016587 , obo:VO_0016592 , obo:VO_0016605 .

obo:VO_0002417 a rdfs:Class ;
  rdfs:label "Canine Distemper-Parvovirus vaccine" ;
  rdfs:subClassOf obo:VO_0001471 , obo:VO_0012178 , obo:VO_0012180 .

obo:BFO_0000001 a rdfs:Class ;
  rdfs:label "entity"@en .

obo:VO_0020237 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020229 .

obo:VO_0004045 a rdfs:Class ;
  rdfs:label "Leishmania major H2B protein vaccine" ;
  rdfs:subClassOf obo:VO_0001231 .

obo:VO_0004834 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Quadracel]" ;
  rdfs:subClassOf obo:VO_0010736 .

obo:VO_0003952 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0011558 .

obo:VO_0016472 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0003646 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003645 .

obo:VO_0004362 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis DNA vaccine encoding Ag85B, MPT64 and MPT83" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:VO_0010107 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii MIC6" ;
  rdfs:comment "A MIC6 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0000811 a rdfs:Class ;
  rdfs:label "vaccine epitope" ;
  rdfs:subClassOf obo:OBI_1110034 .

obo:VO_0007228 a rdfs:Class ;
  rdfs:label "Allogeneic Large Multivalent Immunogen Melanoma Vaccine LP2307" ;
  rdfs:comment "A cancer vaccine, containing human-specific large multivalent immunogen (LMI) isolated from plasma membrane fractions of the melanoma cell lines MSM-M1 and MSM-M2, with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic large multivalent immunogen melanoma vaccine LP2307 may stimulate a CD8+ cytotoxic T lymphocyte (CTL) response against melanoma tumor cells that express melanoma-specific LMI." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0016332 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0015208 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015207 , obo:VO_0015214 , obo:VO_0015302 .

obo:VO_0010195 a rdfs:Class ;
  rdfs:label "influenza, seasonal, Southern Hemisphere, quadrivalent, 0.5mL dose, with preservative" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0002371 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus-Mannheimia Haemolytica-Pasteurella Multocida Vaccine" ;
  rdfs:subClassOf obo:VO_0000620 , obo:VO_0002369 .

obo:VO_0005187 a rdfs:Class ;
  rdfs:label "COVI-VAC vaccine" ;
  rdfs:comment "A SARS-CoV-2 live, attenuated vaccine manufactured by Codagenix, Inc." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005204 , obo:VO_0005264 .

obo:VO_0017558 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0017556 , obo:VO_0017578 .

obo:VO_0015317 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injectable Suspension [Havrix]" ;
  rdfs:subClassOf obo:VO_0000052 , obo:VO_0015315 .

obo:VO_0010973 a rdfs:Class ;
  rdfs:label "Omp16" ;
  rdfs:comment "Brucella Omp16 is a protective antigen [PubMed: 18981242]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0017290 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 , obo:VO_0018778 .

obo:VO_0007201 a rdfs:Class ;
  rdfs:label "Adenovirus 5-Fibroblast Growth Factor 2 Vaccine" ;
  rdfs:comment "Fibroblast growth factor-2-retargeted adenoviral vectors may be used to increase the transduction of GBM-derived endothelial cells, enabling a new and efficient antiangiogenesis strategy for the treatment of malignant gliomas." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0002349 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002350 .

obo:VO_0001845 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Modified Live & Killed Virus Vaccine (USDA: 15B9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0002433 , obo:VO_0007748 .

obo:VO_0005113 a rdfs:Class ;
  rdfs:label "SARS MVA/S vaccine" ;
  rdfs:comment "A SARS recombinant vector vaccine made from a recombinant form of the highly attenuated modified vaccinia virus Ankara (MVA) containing the gene encoding full-length SARS-CoV S" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0020666 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0020656 , obo:VO_0020708 .

obo:VO_0002388 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0002392 .

obo:VO_0003430 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0016643 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0016622 .

obo:VO_0016541 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015984 .

obo:VO_0007669 a rdfs:Class ;
  rdfs:label "HER-2-neu, CEA peptides, GM-CSF, montanide ISA-51 vaccine" ;
  rdfs:comment "A cancer vaccine comprised of HER-2-neu and carcinoembryonic antigen synthetic (CEA) peptides, combined with the adjuvants granulocyte-macrophage colony stimulating factor (GM-CSF), and Montanide ISA-51 with potential antineoplastic activity. The vaccine may stimulate a cytotoxic T-cell response against HER-2-neu- and CEA-expressing tumor cells. Vaccines made from peptides may make the body build an immune response to kill tumor cells. This vaccine is compromised of HER-2-neu and carcinoembryonic antigen synthetic peptides, sargramostim (GM-CSF), and Montanide ISA-51, and aims to cause an immune response in patients with stage IIB, III, or IV colorectal cancer." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005426 , obo:VO_0007657 .

obo:VO_0001924 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002353 .

obo:VO_0007352 a rdfs:Class ;
  rdfs:label "carcinoembryonic antigen peptide 1-6D virus-like replicon particles vaccine" ;
  rdfs:comment "A cancer vaccine, consisting of alphavirus vector-derived virus-like replicon particles expressing the 9-amino-acid carcinoembryonic antigen peptide (CAP) 1-6D, with potential antineoplastic activity. Vaccination with this agent may elicit a cytotoxic T lymphocyte (CTL) immune response against CEA-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0004914 , obo:VO_0007657 .

obo:VO_0005182 a rdfs:Class ;
  rdfs:label "chimpanzee adenovirus Oxford2 vaccine vector" ;
  rdfs:comment "A chimpanzee adenovirus vaccine vector developed by Oxford by deleting E1/E3  from ChAd68 with a modified E4 region." ;
  rdfs:subClassOf obo:VO_0001055 .

obo:VO_0017795 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 600 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017770 , obo:VO_0017804 .

obo:VO_0020279 a rdfs:Class ;
  rdfs:label "typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Injectable Solution [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0000104 , obo:VO_0020278 .

obo:VO_0018373 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003345 .

obo:VO_0001048 a rdfs:Class ;
  rdfs:label "raccoon poxvirus vaccine vector" ;
  rdfs:comment "an orthopoxvirus vaccine vector that uses an attenuated Raccoon poxvirus strain" ;
  rdfs:subClassOf obo:VO_0001146 .

obo:VO_0016375 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015941 .

obo:DOID_10264 a rdfs:Class ;
  rdfs:label "mumps"@en ;
  rdfs:comment "A viral infectious disease that results in inflammation located in salivary gland, has_material_basis_in Mumps rubulavirus, which is transmitted by droplet spread of saliva or mucus from the mouth, nose, or throat of an infected person, or transmitted by contaminated fomites. The infection has symptom fever, has symptom headache, has symptom muscle aches, has symptom tiredness, has symptom loss of appetite, has symptom swollen and tender salivary glands under the ears or jaw on one or both sides of the face."@en ;
  rdfs:subClassOf obo:DOID_77 , obo:DOID_934 .

obo:VO_0001612 a rdfs:Class ;
  rdfs:label "Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.20)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0003399 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Product" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001214 , obo:VO_0003396 , obo:VO_0010436 .

obo:VO_0017115 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017114 .

obo:VO_0004845 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML [Menveo]" ;
  rdfs:subClassOf obo:VO_0001246 , obo:VO_0010445 .

obo:VO_0005483 a rdfs:Class ;
  rdfs:label "CAF01 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant is a gadoteridol-loaded cationic adjuvant formulation 01 that induced a Th1/Th17 type of immune response." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002317 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome-Circovirus Reproductive & Respiratory Form, Type 2, Modifed Live Virus,Killed Baculovirus Vector Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 49K9.R0)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002472 , obo:VO_0007748 .

obo:VO_0020944 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0017970 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Menjugate]" ;
  rdfs:subClassOf obo:VO_0017947 .

obo:VO_0010252 a rdfs:Class ;
  rdfs:label "vaccination dose variable" ;
  rdfs:comment "A variable representing dose representing the vaccination " ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0021152 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML / mumps virus vaccine live, Jeryl Lynn strain 40000 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML / varicella-zoster virus vaccine live (Oka-Merck) strain 20000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000737 .

obo:OBI_0000017 a rdfs:Class ;
  rdfs:label "regulatory role"@en ;
  rdfs:comment "a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0015574 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [H B Vax]" ;
  rdfs:subClassOf obo:VO_0015492 , obo:VO_0015535 .

obo:VO_0011330 a rdfs:Class ;
  rdfs:label "GEL1.00" ;
  rdfs:comment "The GEL1 mRNA of C. posadasii was detected at the highest level during the endosporulation stage of the parasitic cycle, and the mature protein was immunolocalized to the surface of endospores. BALB/c or C57BL/6 mice were immunized subcutaneously with the bacterium-expressed recombinant protein (rGel1p) to evaluate its protective efficacy against a lethal challenge of C. posadasii by either the intraperitoneal or intranasal route. In both cases, rGel1p-immune mice infected with the pathogen showed a significant reduction in fungal burden and increased survival compared to nonimmune mice [PubMed: 12761077]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010853 .

obo:VO_0001886 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002338 .

obo:OBI_0302731 a rdfs:Class ;
  rdfs:label "buffer role"@en ;
  rdfs:comment "a role which inheres in some molecular entity realized during the process of buffering"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0000346 a rdfs:Class ;
  rdfs:label "pWRG7077 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019912 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluzone Intradermal 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020486 .

obo:VO_0021033 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML [Varilrix]" ;
  rdfs:subClassOf obo:VO_0010746 , obo:VO_0021032 .

obo:VO_0018574 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension [Stamaril] Box of 10" ;
  rdfs:subClassOf obo:VO_0018571 , obo:VO_0018577 , obo:VO_0018764 .

obo:VO_0005031 a rdfs:Class ;
  rdfs:label "pcDNA1 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pcDNA1.  This plasmid is 4000 base pairs in length and contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:OPL_0000255 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum salivary gland-derived sporozoite" ;
  rdfs:comment "A Plasmodium falciparum sporozoite that is formed in the oocyst. It migrates to and resides in the salivary glands of the mosquito vector. Sporozoites invade hepatocytes in a human host." ;
  rdfs:subClassOf obo:OPL_0000137 , obo:OPL_0000280 .

obo:VO_0002478 a rdfs:Class ;
  rdfs:label "Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0001456 , obo:VO_0002477 .

obo:VO_0017440 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.08 MG/ML" ;
  rdfs:subClassOf obo:VO_0015014 .

obo:VO_0007728 a rdfs:Class ;
  rdfs:label "prodencel vaccine" ;
  rdfs:comment "A cancer vaccine made with autologous dendritic cells targeting prostate cancer (PC)-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon administration of prodencel, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against PC cells expressing the antigen(s), resulting in tumor cell lysis. (NCIT_C192174) The vaccine could help treat patients with metastatic castration-resistant prostate cancer (mCRPC) after novel androgen-deprived therapy and docetaxel chemotherapy failure." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0000259 a rdfs:Class ;
  rdfs:label "pGEX-3X DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000747 a rdfs:Class ;
  rdfs:label "DNA and MVA encoding ME-TRAP vaccine" ;
  rdfs:comment "A vaccine that contains DNA and modified vaccinia virus Ankara (MVA) encoding thrombospondin-related adhesion protein (TRAP) with a multiple-epitope string ME (ME-TRAP). This vaccine is used with a prime-boost regime by DNA priming and MVA boosting." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000087 .

obo:VO_0018200 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018199 .

obo:BFO_0000026 a rdfs:Class ;
  rdfs:label "one-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:VO_0004323 a rdfs:Class ;
  rdfs:label "Murine cytomegalovirus DNA vaccine pcDNA-89 encoding pp89" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003062 .

obo:VO_0000386 a rdfs:Class ;
  rdfs:label "attenuated Brucella abortus with deletion of znuA vaccine" ;
  rdfs:subClassOf obo:VO_0001134 .

obo:VO_0017435 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0015014 .

obo:VO_0017614 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Pediacel] Box of 10" ;
  rdfs:subClassOf obo:VO_0017613 , obo:VO_0017626 .

obo:VO_0010721 a rdfs:Class ;
  rdfs:label "Infanrix-IPV vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000742 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0007324 a rdfs:Class ;
  rdfs:label "allogeneic GM-CSF-secreting lethally irradiated pancreatic tumor cell vaccine" ;
  rdfs:comment "A cancer vaccine made of allogeneic pancreatic tumor cells are transfected with a GM-CSF gene to treat ocally advanced, unresectable or metastatic pancreatic adenocarcinoma. It may be in combination with Ipilimumab (an antibody that blocks negative signals to T cells)." ;
  rdfs:subClassOf obo:VO_0005430 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0015293 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe [Epaxal]" ;
  rdfs:subClassOf obo:VO_0015291 , obo:VO_0015292 .

obo:VO_0003796 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003795 .

obo:VO_0016461 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0017104 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017103 .

obo:VO_0018667 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 1000 MG" ;
  rdfs:subClassOf obo:VO_0004815 .

obo:NCBITaxon_9606 a rdfs:Class ;
  rdfs:label "Homo sapiens" ;
  rdfs:subClassOf obo:NCBITaxon_9526 .

obo:VO_0002686 a rdfs:Class ;
  rdfs:label "htrA from Yersinia enterocolitica" ;
  rdfs:comment "A htrA mutant in Yersinia enterocolitica was attenuated and provided partial protection against challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001425 .

obo:VO_0002525 a rdfs:Class ;
  rdfs:label "mntA from Bacillus anthracis" ;
  rdfs:comment "An mntA deletion mutant, generated by allelic replacement, in Bacillus anthracis was attenuated and provided protection for guinea pigs against lethal spore dose (60 LD50) of the virulent B. anthracis Vollum strain" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001402 .

obo:VO_0019432 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.036 MG/ML / Haemophilus capsular oligosaccharide 0.05 MG/ML [Prohibit]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000660 , obo:VO_0001214 , obo:VO_0010437 , obo:VO_0010445 .

obo:VO_0010156 a rdfs:Class ;
  rdfs:label "Anthrax vaccine, adsorbed, pre-exposure and post-exposure prophylaxis" ;
  rdfs:subClassOf obo:VO_0000014 .

obo:VO_0003587 a rdfs:Class ;
  rdfs:label "Fluzone 2016-2017 High-Dose vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000079 , obo:VO_0003584 .

obo:VO_0018678 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 Powder for Oral Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018674 .

obo:VO_0019719 a rdfs:Class ;
  rdfs:label "influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010423 .

obo:VO_0017505 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017502 .

obo:VO_0016580 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Hepatitis B Surface Antigen Vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000745 , obo:VO_0001214 .

obo:VO_0010992 a rdfs:Class ;
  rdfs:label "Spa32" ;
  rdfs:comment "S. flexneri M90T is a colonisation-defective mutant with a transposon in fnr, which encodes a regulator of anaerobic metabolism. To establish whether FNR-mediated repression of spa32 and spa33 contributes to increased Shigella entry into cells in an anaerobic cabinet, recombinant M90T strains were constructed which contain spa32 and spa33 under the control of either their native promoters (M90Tp32/33) or promoters with disrupted FNR boxes (M90Tp#32/#33).The presence in M90T of spa32 and spa33 alleles that are not repressed by FNR led to IpaB secretion during anaerobic growth, and loss of the increased entry of Shigella into cells in an anaerobic cabinet [PubMed: 20436458]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010777 .

obo:VO_0015219 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015218 .

obo:VO_0000774 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum RTS,S/AS02A vaccine" ;
  rdfs:comment "RTS,S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium falciparum circumsporozoite surface antigen." ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000455 .

obo:VO_0017672 a rdfs:Class ;
  rdfs:label "Meningococcal-Haemophilis B-Tetanus Vaccine" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000662 , obo:VO_0003396 .

obo:VO_0019274 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:VO_0004616 a rdfs:Class ;
  rdfs:label "Multivalent immunotherapeutic vaccine" ;
  rdfs:comment "The approach focuses on the use of five primary patient derived melanoma cells (MEL-2, MEL-V, 3MM, KFM, and GLM-2). These cells display differential in vitro migratory and invasive properties as well as have the ability to form solid tumors when implanted into BALB/c nude mice. The retention of the innate phenotype of these primary patient derived cells together with the expression of a multitude repertoire of melanoma associated antigens offers a novel opportunity to target melanoma so as to avoid immune evasion" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0002024 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 4C95.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002379 .

obo:VO_0012366 a rdfs:Class ;
  rdfs:label "FbpD" ;
  rdfs:comment "Intravenous vaccination with recombinant bacteria carrying expression plasmid for  MPB/MPT51 in BALB/c mice elicited significant protective responses, comparable to those evoked by a live Mycobacterium bovis BCG vaccine [PubMed: 15039321]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0010037 a rdfs:Class ;
  rdfs:label "Neospora caninum SAG1" ;
  rdfs:comment "A SAG1 protein that is part of Neospora caninum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0000831 a rdfs:Class ;
  rdfs:label "recombinant Yersinia pestis V antigen vaccine" ;
  rdfs:comment "A Y. pestis subunit vaccine that uses recombinant Y. pestis V antigen. PMID:7622205." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000648 .

obo:VO_0017264 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017230 .

obo:VO_0004138 a rdfs:Class ;
  rdfs:label "CVD 909 vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000768 .

obo:VO_0003791 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003070 , obo:VO_0010433 .

obo:VO_0004775 a rdfs:Class ;
  rdfs:label "NYVAC-HIV-2 vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0017535 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution [Tetabulin] Box of 1" ;
  rdfs:subClassOf obo:VO_0017534 , obo:VO_0017536 .

obo:VO_0003907 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003906 .

obo:VO_0000683 a rdfs:Class ;
  rdfs:label "vaccine regulation" ;
  rdfs:comment "Process that regulates vaccine-related processes, such as vaccine trial, vaccine license application." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0019237 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0020321 .

obo:CL_0000235 a rdfs:Class ;
  rdfs:label "macrophage" ;
  rdfs:comment "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." ;
  rdfs:subClassOf obo:CL_0000113 , obo:CL_0000766 .

obo:VO_0000544 a rdfs:Class ;
  rdfs:label "human vaccinee" ;
  rdfs:comment "a vaccinee that is a human being" ;
  rdfs:subClassOf obo:VO_0001374 .

obo:VO_0015306 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015298 .

obo:VO_0019713 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003584 , obo:VO_0019712 .

obo:VO_0002322 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4BC5.21)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002460 , obo:VO_0007748 .

obo:VO_0019353 a rdfs:Class ;
  rdfs:label "0.7 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017096 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017567 .

obo:VO_0020825 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0000950 a rdfs:Class ;
  rdfs:label "Salmonella typhi-Hepatitis A vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000563 , obo:VO_0000646 , obo:VO_0000671 .

obo:VO_0011134 a rdfs:Class ;
  rdfs:label "NP from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ;
  rdfs:comment "Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later. The mice immunized with NP plasmid showed 60-80% survival rate with at least three immunizations.  The mixture of M1 and NP plasmids protected 95% of the mice against the homologous virus, and 80% of the mice against a challenge with heterologous H1N1 (PR8) virus [PubMed: 19067149]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0015754 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015814 .

obo:VO_0020193 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA spike protein" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0002117 a rdfs:Class ;
  rdfs:label "Canine Distemper-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14D7.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002482 , obo:VO_0007748 .

obo:VO_0007080 a rdfs:Class ;
  rdfs:label "Telomerase-specific Type 5 Adenovirus OBP-301 Vaccine" ;
  rdfs:comment "A replication-competent oncolytic, telomerase-specific adenovirus serotype 5 (Ad5), with potential antineoplastic activity. OBP-301 contains the human telomerase reverse transcriptase (hTERT) gene promoter sequence that drives the expression of the E1A and E1B genes, and is linked to an internal ribosomal entry site (IRES). Upon administration, OBP-301 selectively infects and replicates in cancer cells that are expressing telomerase, which causes cell lysis. This adenovirus does not infect or replicate in normal, healthy cells. OBP-301 may also potentially be used as a chemosensitizer. hTERT, which encodes for the catalytic protein subunit of telomerase, is overexpressed in a variety of cancer cell types but not in normal, healthy cells. The insertion of an IRES further improves selectivity towards telomerase-expressing cancer cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005429 , obo:VO_0007657 .

obo:VO_0007605 a rdfs:Class ;
  rdfs:label "FVAX vaccine" ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000652 , obo:VO_0007657 .

obo:VO_0018734 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 2000000000 ORGANISMS Delayed Release Oral Capsule" ;
  rdfs:subClassOf obo:VO_0018732 .

obo:NCBITaxon_2732525 a rdfs:Class ;
  rdfs:label "Pokkesviricetes" ;
  rdfs:subClassOf obo:NCBITaxon_2732005 .

obo:VO_0004508 a rdfs:Class ;
  rdfs:label "PRRSV DNA vaccine pIRESorf5/IL-2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001802 .

obo:VO_0017039 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 100" ;
  rdfs:subClassOf obo:VO_0017032 , obo:VO_0017046 , obo:VO_0017510 .

obo:VO_0005494 a rdfs:Class ;
  rdfs:label "renal cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against renal cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0020569 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Inflexal]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020867 .

obo:VO_0016192 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:VO_0018031 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003835 .

obo:UBERON_0001134 a rdfs:Class ;
  rdfs:label "skeletal muscle tissue" ;
  rdfs:comment "Muscle tissue that consists primarily of skeletal muscle fibers." ;
  rdfs:subClassOf obo:UBERON_0002385 .

obo:VO_0004034 a rdfs:Class ;
  rdfs:label "Francisella tularensis FopB protein vaccine" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0018436 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumopur] Box of 10" ;
  rdfs:subClassOf obo:VO_0018421 .

obo:VO_0010462 a rdfs:Class ;
  rdfs:label "vaccine-induced cell-mediated immune response" ;
  rdfs:subClassOf obo:VO_0000135 .

obo:VO_0007077 a rdfs:Class ;
  rdfs:label "WT1-A10/AS01B Immunotherapeutic GSK2130579A Vaccine" ;
  rdfs:comment "An immunotherapeutic consisting of the recombinant fusion protein WT1-A10 combined with the adjuvant ASO1B with potential immunostimulating and antineoplastic activities. Upon administration, WT1-A10/AS01B immunotherapeutic GSK2130579AWT1 may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1-expressing tumor cells, resulting in cell lysis and the inhibition of cellular proliferation. The tumor-associated antigen WT1 (Wilms tumor protein-1) is overexpressed in most types of leukemia and in a variety of solid cancers. WT1-A10 is a 292 amino acid recombinant fusion protein consisting of a 12-mer truncated tat sequence (leader sequence) and amino acids number 2-281 of the WT1 sequence; ASO1B consists of a combination of the adjuvants monophosporyl lipd A (MPL) and Q21." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0000446 a rdfs:Class ;
  rdfs:label "licensed chicken vaccine" ;
  rdfs:subClassOf obo:VO_0000657 , obo:VO_0001468 .

obo:VO_0006034 a rdfs:Class ;
  rdfs:label "meningococcal vaccine of unknown formulation and unknown serogroups" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0020995 a rdfs:Class ;
  rdfs:label "Influenza Virus Vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.009 MG/ML" ;
  rdfs:subClassOf obo:VO_0003504 .

obo:VO_0016386 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 3 by Mtk" ;
  rdfs:subClassOf obo:VO_0015946 .

obo:VO_0004429 a rdfs:Class ;
  rdfs:label "B16 melanoma DNA vaccine pSin-hTRP-1 encoding TRP-1" ;
  rdfs:comment "Gene name: TYRP1" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0001317 a rdfs:Class ;
  rdfs:label "Theramide vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant called Theramide that is composed of N-acetylglucosaminyl-N-acetylinuramyl-L-Ala-D-isoGlu-L-Ala-dipalmitoxy propylamide (DTP-DPP)." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0021089 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 .

obo:VO_0019263 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0011107 a rdfs:Class ;
  rdfs:label "HPV E6" ;
  rdfs:comment "C57BL/6 mice vaccinated with pNGVL4a-E6/opt are able to generate potent protective and therapeutic antitumor effects against challenge with E6-expressing tumor cell line, TC-1 of HPV [PubMed: 16649071]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010786 .

obo:VO_0020332 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2019-2020 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003070 , obo:VO_0010420 .

obo:VO_0002873 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP mutant vaccine (merged to VO_0002872)" ;
  rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" .

obo:DOID_0060073 a rdfs:Class ;
  rdfs:label "lymphatic system cancer"@en ;
  rdfs:comment "An immune system cancer that is located_in the lymphatic system and is characterized by uncontrolled cellular proliferation of lymphoid tissue."@en ;
  rdfs:subClassOf obo:DOID_0060083 .

obo:VO_0019849 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML [Flulaval Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020345 .

obo:VO_0004829 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 1400000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0004823 .

obo:VO_0018082 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 25000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018081 , obo:VO_0018163 .

obo:VO_0011370 a rdfs:Class ;
  rdfs:label "Cancer EPCAM protein vaccine" ;
  rdfs:comment "Gene name: EPCAM" ;
  rdfs:subClassOf obo:VO_0005429 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0004370 a rdfs:Class ;
  rdfs:label "Herpes simplex virus DNA vaccine encoding gD and gB from HSV-2 strain Curtis" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0007143 a rdfs:Class ;
  rdfs:label "NY-ESO-1/LAGE-1 peptide vaccine" ;
  rdfs:comment "A cancer vaccine containing HLA class I- and II-binding peptides derived from the NY-ESO-1/LAGE-1 cancer/testis antigen with potential immunostimulatory and antineoplastic activities. Upon administration, NY-ESO-1/LAGE-1 HLA class I/II peptide vaccine may induce a cytotoxic immune response against tumor cells that over-express NY-ESO-1/LAGE-1. Rarely expressed by normal cells, the NY-ESO-1/LAGE-1 cancer/testis antigen has been shown to be preferentially expressed on the surface of some cancer cell types." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:NCBITaxon_590 a rdfs:Class ;
  rdfs:label "Salmonella" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:VO_0011346 a rdfs:Class ;
  rdfs:label "DeltaFTT0918 vaccine" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0017085 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Covaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0017084 , obo:VO_0017114 , obo:VO_0017562 .

obo:VO_0004806 a rdfs:Class ;
  rdfs:label "Mycobacterium bovis DNA vaccine pCI-Ag85B" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001519 .

obo:VO_0005107 a rdfs:Class ;
  rdfs:label "Salmonella-tPA-S SARS DNA vaccine" ;
  rdfs:comment "A SARS DNA vaccine made from  CTLA4HingeSARS800 DNA with SARS-CoV S protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012183 .

obo:UBERON_0002358 a rdfs:Class ;
  rdfs:label "peritoneum" ;
  rdfs:comment "A serous membrane that lines the peritoneal cavity[VHOG,modified]." ;
  rdfs:subClassOf obo:UBERON_0000042 .

obo:VO_0015118 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015111 .

obo:VO_0019997 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe [Fluzone Intradermal 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020487 .

obo:VO_0010009 a rdfs:Class ;
  rdfs:label "Giardia  duodenalis a1-giardin" ;
  rdfs:comment "A a1-giardin protein that is part of Giardia  duodenalis" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010829 .

obo:VO_0016423 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 25 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015970 .

obo:VO_0018196 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus vaccine Prefilled Syringe [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018195 .

obo:VO_0000152 a rdfs:Class ;
  rdfs:label "Francisella tularensis vaccine" ;
  rdfs:comment "a bacterial vaccine against an infection with F. tularensis." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0016816 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0016732 , obo:VO_0016765 .

obo:VO_0001951 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44M5.20)" ;
  rdfs:subClassOf obo:VO_0002359 .

obo:VO_0020296 a rdfs:Class ;
  rdfs:label "yellow fever virus strain 17D-204 live antigen 4000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0003371 .

obo:VO_0001375 a rdfs:Class ;
  rdfs:label "Streptococcus agalactiae vaccine" ;
  rdfs:comment "A Streptococcus  vaccine against Streptococcus agalactiae infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000772 .

obo:VO_0011565 a rdfs:Class ;
  rdfs:label "Neospora caninum NcDG2 protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0001065 .

obo:NCBITaxon_11250 a rdfs:Class ;
  rdfs:label "human respiratory syncytial virus" ;
  rdfs:subClassOf obo:NCBITaxon_1868215 .

obo:VO_0003627 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010432 .

obo:VO_0003042 a rdfs:Class ;
  rdfs:label "protective vaccine antigen" ;
  rdfs:comment "the vaccine antiegn that induces protective immune response. " ;
  rdfs:subClassOf obo:VO_0000919 , obo:VO_0001232 .

obo:VO_0019512 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010325 , obo:VO_0010438 .

obo:VO_0016258 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015919 .

obo:VO_0015166 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015164 .

obo:VO_0011011 a rdfs:Class ;
  rdfs:label "YerA" ;
  rdfs:comment "Using a mouse plague model, YPCD1.05c (yerA) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0000978 a rdfs:Class ;
  rdfs:label "Flublok" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0017762 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017760 , obo:VO_0017806 .

obo:VO_0019533 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.04 MG/ML Prefilled Syringe [Heplisav-B]" ;
  rdfs:subClassOf obo:VO_0003152 , obo:VO_0015499 .

obo:VO_0011244 a rdfs:Class ;
  rdfs:label "VP4 from Poliovirus" ;
  rdfs:comment "To examine the mechanism of immunity in vivo, researchers used poliovirus receptor-transgenic mice on a BALB/c (H-2d) background.  Mice immunized with the vaccine strain were protected against a subsequent challenge with wild-type virus.  Protection was observed when mice received primed B cells in the presence of a VP4-specific Th1 clone.   Findings demonstrate that CD4+ T cells, specific for the internal poliovirus capsid protein, VP4, can provide effective help for a protective antibody response directed against surface capsid proteins [PubMed: 7699320]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010787 .

obo:VO_0003441 a rdfs:Class ;
  rdfs:label "meningococcal conjugate vaccine" ;
  rdfs:comment "Meningococcal conjugate vaccine, which contains four of the most common types of meningococcal bacteria (serogroups A, C, W, and Y), is used to prevent infection caused by meningococcal bacteria." ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000195 .

obo:VO_0010419 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2011-2012" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0002760 a rdfs:Class ;
  rdfs:label "py52 from Plasmodium yoelii" ;
  rdfs:comment "A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001452 .

obo:VO_0001090 a rdfs:Class ;
  rdfs:label "vaccinee priority group" ;
  rdfs:comment "A population group that have priority for  vaccination when a vaccine is first available." ;
  rdfs:subClassOf obo:VO_0000546 .

obo:RO_0002351 a rdf:Property ;
  rdfs:label "has member"@en ;
  rdfs:comment "has member is a mereological relation between a collection and an item." ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:VO_0018609 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 805000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004822 .

obo:VO_0000923 a rdfs:Class ;
  rdfs:label "RECOMBITEK Corona MLV vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000649 , obo:VO_0000932 .

obo:VO_0010066 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii HEP17" ;
  rdfs:comment "A HEP17 protein that is part of Plasmodium yoelii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015474 .

obo:VO_0017784 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0017780 , obo:VO_0017788 .

obo:VO_0019282 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluarix Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020319 .

obo:VO_0010989 a rdfs:Class ;
  rdfs:label "C0393" ;
  rdfs:comment "Active immunization of BALB/c mice with C0393  antigen in Freund's adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0011387 a rdfs:Class ;
  rdfs:label "NP-VRP vaccine" ;
  rdfs:comment "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus NP protein." ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0003638 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010433 .

obo:VO_0015678 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015563 , obo:VO_0015772 .

obo:VO_0016152 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015887 .

obo:VO_0017331 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0017329 .

obo:VO_0020731 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Suspension [ImmuCyst] Box of 1" ;
  rdfs:subClassOf obo:VO_0020730 , obo:VO_0020734 .

obo:VO_0018620 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018799 , obo:VO_0018800 .

obo:VO_0004610 a rdfs:Class ;
  rdfs:label "SRL172 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020017 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 50000000 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 50000000 MG/ML Nasal Spray [Flumist 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020350 .

obo:NCBITaxon_10566 a rdfs:Class ;
  rdfs:label "Human papillomavirus" ;
  rdfs:subClassOf obo:NCBITaxon_333774 .

obo:VO_0012158 a rdfs:Class ;
  rdfs:label "Leishmania amazonensis vaccine" ;
  rdfs:comment "A vaccine that protects against Leishmania amazonensis." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000762 .

obo:NCBITaxon_11290 a rdfs:Class ;
  rdfs:label "Infectious hematopoietic necrosis virus" ;
  rdfs:subClassOf obo:NCBITaxon_186778 .

obo:VO_0010422 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2016" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0017906 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injection [Meningitec]" ;
  rdfs:subClassOf obo:VO_0017849 .

obo:VO_0002667 a rdfs:Class ;
  rdfs:label "znuC from Salmonella Typhimurium" ;
  rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0017465 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 1.5 UNT/ML [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017464 .

obo:VO_0003171 a rdfs:Class ;
  rdfs:label "MR-VAX II vaccine" ;
  rdfs:comment "A live virus vaccine for immunization against measles and rubella." ;
  rdfs:subClassOf obo:VO_0000945 , obo:VO_0001220 .

obo:VO_0002750 a rdfs:Class ;
  rdfs:label "obsolete E1 from Western equine encephalomyelitis virus" ;
  rdfs:comment "A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" .

obo:VO_0002536 a rdfs:Class ;
  rdfs:label "panC from Mycobacterium tuberculosis" ;
  rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0016279 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015924 .

obo:VO_0004888 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide" ;
  rdfs:comment "TUI: T200" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0010739 a rdfs:Class ;
  rdfs:label "Td Adsorbed vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0017212 a rdfs:Class ;
  rdfs:label "10 ML tetanus toxoid vaccine, inactivated 8 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017211 , obo:VO_0017586 .

obo:VO_0018110 a rdfs:Class ;
  rdfs:label "1 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0018109 , obo:VO_0018176 .

obo:VO_0002177 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 17A1.1M)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0004815 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010449 .

obo:VO_0010185 a rdfs:Class ;
  rdfs:label "influenza, recombinant, trivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0010415 .

obo:VO_0002338 a rdfs:Class ;
  rdfs:label "bovine rhinotracheitis-parainfluenza 3 vaccine" ;
  rdfs:subClassOf obo:VO_0000987 , obo:VO_0000990 .

obo:VO_0000494 a rdfs:Class ;
  rdfs:label "vaccine immunization" ;
  rdfs:comment "Immunization that is induced by a vaccine via vaccination process." ;
  rdfs:subClassOf obo:OBI_0000011 , obo:VO_0000490 .

obo:OGG_3000888491 a rdfs:Class ;
  rdfs:label "drrC" ;
  rdfs:comment "Probable daunorubicin-dim-transport integral membrane protein ABC transporter DrrC" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0000371 a rdfs:Class ;
  rdfs:label "quaternary vaccination" ;
  rdfs:comment "quaternary vaccination is a vaccination that is performed at the fourth  time in a row." ;
  rdfs:subClassOf obo:VO_0000708 .

obo:VO_0020173 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020170 .

obo:VO_0015707 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 20" ;
  rdfs:subClassOf obo:VO_0015570 , obo:VO_0015790 .

obo:VO_0005374 a rdfs:Class ;
  rdfs:label "therapeutic vaccination" ;
  rdfs:comment "A vaccination process that involves adding a vaccine into a host after a disease has occurred." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0004251 a rdfs:Class ;
  rdfs:label "recombinant S gene Hepatitis B vaccine with rIFN-gamma" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000644 .

obo:VO_0015651 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015561 , obo:VO_0015673 .

obo:VO_0000990 a rdfs:Class ;
  rdfs:label "Bovine parainfluenza 3 virus vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 , obo:VO_0001466 .

obo:VO_0017451 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide / tetanus toxoid vaccine, inactivated Injectable Suspension [Neisvac C]" ;
  rdfs:subClassOf obo:VO_0017450 .

obo:VO_0020457 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 100 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020442 .

obo:VO_0007530 a rdfs:Class ;
  rdfs:label "follicular lymphoma, patient-specific, soluble protein idiotype vaccine" ;
  rdfs:comment "A cancer vaccine directed against the soluble protein idiotype of an individual follicular lymphoma with potential antineoplastic activity. The vaccine may induce an idiotype-specific cytotoxic T-lymphocyte (CTL) response against follicular lymphoma cells expressing the idiotype, resulting in tumor cell lysis. Idiotypic vaccinations have the capacity of inducing an idiotype- and tumor-specific immune response, inducing specific immune responses able to kill in vivo follicular lymphoma cells, and prolonging survival of responding patients. This vaccine may contribute to preventing relapse indefinitely in responding patients." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0001273 a rdfs:Class ;
  rdfs:label "Polygen vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant with the tradename Polygen." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0016909 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.016 MG/ML / Bordetella pertussis 0.1 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016908 .

obo:VO_0019163 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0018615 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus Injection [Imojev]" ;
  rdfs:subClassOf obo:VO_0018614 .

obo:VO_0020536 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML Injectable Solution [HibTITER] Box of 5 by Praxis Biologics" ;
  rdfs:subClassOf obo:VO_0020535 .

obo:OBI_0100046 a rdfs:Class ;
  rdfs:label "phosphate buffered saline solution"@en ;
  rdfs:comment "Phosphate buffered saline (abbreviated PBS) is a buffer solution commonly used in biochemistry. It is a salty solution containing sodium chloride, sodium phosphate and in some preparations potassium chloride and potassium phosphate. The buffer helps to maintain a constant pH. The concentration usually matches the human body (isotonic)."@en ;
  rdfs:subClassOf obo:OBI_0302729 .

obo:NCBITaxon_9685 a rdfs:Class ;
  rdfs:label "Felis catus" ;
  rdfs:subClassOf obo:NCBITaxon_9682 .

obo:VO_0001394 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi vaccine using Sendai virus vector expressing amastigote surface protein-2" ;
  rdfs:comment "A T. cruzi vaccine that uses Sendai virus vector to express T. cruzi amastigote surface protein-2." ;
  rdfs:subClassOf obo:VO_0001385 .

obo:VO_0004635 a rdfs:Class ;
  rdfs:label "rSPV-MRP Streptococcus suis vaccine" ;
  rdfs:subClassOf obo:VO_0002788 .

obo:VO_0002771 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae apxIIIB and apxIIID double mutant vaccine" ;
  rdfs:comment "An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0003106 a rdfs:Class ;
  rdfs:label "diphtheria, tetanus and whole cell pertussis vaccine" ;
  rdfs:subClassOf obo:VO_0000738 .

obo:VO_0000428 a rdfs:Class ;
  rdfs:label "phase 2 vaccine trial" ;
  rdfs:comment "A vaccine clinical trial that studies vaccine efficacy with a target population (numbering 50-100). Different dosage levels will also be explored at this stage to determine the optimum dose." ;
  rdfs:subClassOf obo:VO_0000596 .

obo:VO_0015132 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015126 , obo:VO_0015297 .

obo:VO_0020141 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0003441 , obo:VO_0010444 , obo:VO_0010445 .

obo:VO_0001511 a rdfs:Class ;
  rdfs:label "Porcine respiratory and reproductive syndrome virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Porcine respiratory and reproductive syndrome virus (Porcine reproductive and respiratory syndrome virus) infection" ;
  rdfs:subClassOf obo:VO_0000609 , obo:VO_0001474 .

obo:VO_0007132 a rdfs:Class ;
  rdfs:label "Ovarian Cancer Stem Cell/hTERT/Survivin mRNAs-loaded Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cancer vaccine containing autologous dendritic cells (DCs) that are transfected with mRNAs extracted from amplified ovarian cancer stem cells, and mRNAs of the universal tumor antigens human telomerase reverse transcriptase (hTERT) and survivin with potential immunostimulatory and antineoplastic activities. Upon administration, ovarian cancer stem cell/hTERT/survivin mRNAs-loaded autologous DC-006 vaccine may elicit a highly specific cytotoxic T-cell (CTL) response against ovarian cancer cells expressing hTERT, survivin, and specific ovarian cancer stem cell antigens. hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types, playing key roles in tumor cell growth and survival. Ovarian cancer stem cells contain a specific range of antigens that are essential for the neoplastic growth and survival of ovarian cancer cells." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0011408 a rdfs:Class ;
  rdfs:label "Herpes simplex virus type 1 DNA vaccine encoding GC" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000958 .

obo:VO_0007602 a rdfs:Class ;
  rdfs:label "electroloading of mature dendritic cells with melanoma whole tumor cell lysate vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:NCBITaxon_10469 a rdfs:Class ;
  rdfs:label "unidentified baculovirus" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:VO_0018754 a rdfs:Class ;
  rdfs:label "Tick-borne encephalitis virus inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018753 .

obo:VO_0010433 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2017-2018" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0003678 a rdfs:Class ;
  rdfs:label "Fluvirin 2015-2016 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003676 .

obo:VO_0004268 a rdfs:Class ;
  rdfs:label "HIV-1 gp120 with mCT E112K vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0007251 a rdfs:Class ;
  rdfs:label "AML mRNA Positive Lysate Loaded Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous dendritic cells loaded with separate preparations of acute myelogenous leukemia (AML) cell lysate and AML-specific messenger RNA (mRNA) with potential immunostimulatory and antineoplastic activities. Upon administration, AML mRNA plus lysate loaded autologous dendritic cell vaccine may elicit a potent cytotoxic T-cell (CTL) response against AML cells, resulting in tumor cell death. Autologous dendritic cells doubly-loaded with AML cell lysate and AML-specific mRNA may elicit superior primary, recall, and effector lytic immune responses compared to autologous dendritic cells loaded with tumor lysate or tumor mRNA alone." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0000912 a rdfs:Class ;
  rdfs:label "chicken egg protein allergen" ;
  rdfs:comment "chicken egg protein allergen is a vaccine allergen that is composed of chicken egg protein." ;
  rdfs:subClassOf obo:VO_0000910 .

obo:VO_0001251 a rdfs:Class ;
  rdfs:label "LTK63 vaccine mutant" ;
  rdfs:comment "An E. coli LT toxin derived vaccine adjuvant that is a mutant form of LT containing a Ser-Lys substitution in position 63 which has been shown to be totally devoid of toxicity stable to protease treatment and able to act as mucosal adjuvant." ;
  rdfs:subClassOf obo:VO_0000388 .

obo:VO_0007697 a rdfs:Class ;
  rdfs:label "MT-201-GBM monocyte vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous monocytes loaded with mRNA encoding the human cytomegalovirus (CMV) matrix protein pp65 (65 kDa lower matrix phosphoprotein; UL83) as a fusion protein with the lysosome-associated membrane protein (LAMP), with potential immunostimulatory and antineoplastic activities. The autologous CMV-pp65-LAMP mRNA loaded monocyte vaccine MT-201-GBM exposes the immune system to the CMV pp65 peptide, which may elicit a cytotoxic T-lymphocyte (CTL) response against CMV pp65-expressing tumor cells. The incorporation of LAMP may route CMV pp-65 antigens into the lysosomal compartment, resulting in enhanced MHC class II antigen presentation, thereby promoting CD4-positive T-cell responses. MT-201-GBM (pp65CMV antigen monocytes) are administered to patients newly diagnosed with a type of brain tumor called glioblastoma (GBM) that has an unmethylated MGMT (O[6]-methylguanine-DNA methyltransferase) (MGMT) gene promoter. The vaccine is made from a type of immune cell called monocytes, which have been engineered to express a cytomegalovirus (CMV) protein. Patients also receive standard radiation therapy combined with temozolomide." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0016788 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016733 .

obo:VO_0016225 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Mtk" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:VO_0015834 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015606 .

obo:VO_0011526 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus DNA vaccine encoding CAB049" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001085 .

obo:VO_0007694 a rdfs:Class ;
  rdfs:label "mRNA neoantigen tumor vaccine" ;
  rdfs:comment "A cancer vaccine with or without PD-1/L1 may help treat patients with advanced gastric cancer. A personalized mRNA tumor vaccine encoding neoantigen may also help treat patients with advanced esophageal squamous carcinoma, gastric adenocarcinoma, pancreatic adenocarcinoma and colorectal adenocarcinoma. The vaccine can also be used in combination with PD-1 for the treatment of advanced solid tumors." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0007657 .

obo:VO_0004418 a rdfs:Class ;
  rdfs:label "Eimeria acervulina DNA vaccine 3-1E" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000906 .

obo:VO_0011548 a rdfs:Class ;
  rdfs:label "Francisella tularensis DNA vaccine pTUL4-15" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000152 .

obo:VO_0001424 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 gene" ;
  rdfs:comment "A viral gene that is from Bovine herpesvirus 1." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0001548 a rdfs:Class ;
  rdfs:label "Feline Leukemia Killed Virus Vaccine (USDA: 1555.R1)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0000843 , obo:VO_0007748 .

obo:VO_0004455 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine T.g.HSP70" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:VO_0017245 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Hepatitis B Surface Antigen Vaccine / tetanus toxoid vaccine, inactivated Prefilled Syringe [Eurim Pharm]" ;
  rdfs:subClassOf obo:VO_0017243 .

obo:VO_0015662 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015493 .

obo:VO_0015967 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 1" ;
  rdfs:subClassOf obo:VO_0003265 .

obo:VO_0004240 a rdfs:Class ;
  rdfs:label "synthetic OMP1 vaccine" ;
  rdfs:subClassOf obo:VO_0001207 .

obo:VO_0020178 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (human), inactivated 2.5 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003858 , obo:VO_0020180 .

obo:VO_0011551 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae D15 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012185 .

obo:VO_0004273 a rdfs:Class ;
  rdfs:label "YopE(67-77) protein vaccine" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:IDO_0000528 a rdfs:Class ;
  rdfs:label "pathogen"@en ;
  rdfs:comment "A material entity with a pathogenic disposition."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0002037 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.40)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002326 , obo:VO_0007748 .

obo:VO_0010476 a rdfs:Class ;
  rdfs:label "Diphtheria, Tetanus, and acellular Pertussis vaccine" ;
  rdfs:subClassOf obo:VO_0000738 .

obo:VO_0015791 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 25" ;
  rdfs:subClassOf obo:VO_0015491 .

obo:VO_0016769 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 2" ;
  rdfs:subClassOf obo:VO_0016719 .

obo:VO_0010941 a rdfs:Class ;
  rdfs:label "CS1" ;
  rdfs:comment "ETEC also expresses a range of colonisation factor antigens (CFAs), which allow adherence to the mucosal surface and therefore colonisation of the intestine. Some CFAs are sub-divided into coli surface (CS) antigens [PubMed: 17566016]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0020102 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.0000000385 MG/ML Injectable Suspension [Je-Vax]" ;
  rdfs:subClassOf obo:VO_0020100 , obo:VO_0020101 , obo:VO_0020105 .

obo:VO_0018328 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0018318 .

obo:VO_0001012 a rdfs:Class ;
  rdfs:label "classical swine fever virus vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003546 .

obo:VO_0019986 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Fluarix 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019973 .

obo:VO_0016462 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0018317 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Injectable Solution by Aventis" ;
  rdfs:subClassOf obo:VO_0018287 .

obo:VO_0015780 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 25" ;
  rdfs:subClassOf obo:VO_0015595 .

obo:VO_0004502 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pCAGGoptiHA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0020260 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 0.5 ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020259 .

obo:VO_0016111 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015872 .

obo:NCBITaxon_11149 a rdfs:Class ;
  rdfs:label "Transmissible gastroenteritis virus" ;
  rdfs:subClassOf obo:NCBITaxon_693997 .

obo:VO_0018507 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0018503 .

obo:VO_0001225 a rdfs:Class ;
  rdfs:label "Brucella abortus DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000108 .

obo:VO_0000431 a rdfs:Class ;
  rdfs:label "Francisella tularensis DNA vaccine rLm/iglC" ;
  rdfs:comment "Seven F. tularensis proteins including IglC (rLm/iglC) were expressed in recombinant L. monocytogenes (rLm) vaccines. These 7 F. tularensis proteins are: AcpA, Bfr, DnaK, GroEL, IglC, Pld and KatG from SchuS4 strain." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000152 .

obo:VO_0002606 a rdfs:Class ;
  rdfs:label "aroA from Mannheimia haemolytica" ;
  rdfs:comment "An aroA mutant is highly attenuated in mice and induced significant protection after two doses from challenge with wild type M. haemolytica" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001415 .

obo:VO_0017044 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0017031 , obo:VO_0017513 .

obo:VO_0007428 a rdfs:Class ;
  rdfs:label "MVA-MUC1-IL2 vaccine" ;
  rdfs:comment "A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory activity against antigens. Vaccination with MVA-MUC1-IL2 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing MUC1, a tumor associated antigen, resulting in tumor cell lysis. Expression of IL-2 augments the specific CTL response against MUC1 expressing cells." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0017715 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0017714 , obo:VO_0017724 , obo:VO_0017781 .

obo:VO_0000086 a rdfs:Class ;
  rdfs:label "pBudCE4.1 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0011273 a rdfs:Class ;
  rdfs:label "TSA from Leishmania major" ;
  rdfs:comment "Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge with L. major.  Mice inoculated pCMV3ISS-TSA developed significantly smaller lesions in their footpads after challenge with the parasite.  The vaccine was able to induce a partially protective effect [PubMed: 18951941]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0002463 a rdfs:Class ;
  rdfs:label "Porcine Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae vaccine" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0001474 , obo:VO_0001494 .

obo:VO_0018098 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018233 .

obo:VO_0004328 a rdfs:Class ;
  rdfs:label "Human papillomavirus DNA vaccine VlJns-Ll encoding L1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000667 .

obo:VO_0012393 a rdfs:Class ;
  rdfs:label "BPS" ;
  rdfs:comment "Immunization of mice with recombinant BPS protein by the subcutaneous route produced an efficient antigen-specific response, and immunized animals survived challenge with a lethal dose of a virulent strain [PubMed: 11796614]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012356 .

obo:VO_0010822 a rdfs:Class ;
  rdfs:label "Eimeria spp. protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0003576 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0088 MG/ML / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML [Prevnar 13]" ;
  rdfs:subClassOf obo:VO_0001244 .

obo:VO_0000128 a rdfs:Class ;
  rdfs:label "aluminum phosphate vaccine adjuvant" ;
  rdfs:comment "An aluminum vaccine adjuvant that is aluminum phosphate." ;
  rdfs:subClassOf obo:VO_0000884 .

obo:VO_0010935 a rdfs:Class ;
  rdfs:label "H3L" ;
  rdfs:comment "Mice were immunized with recombinant H3L protein to examine H3L-specific antibody responses in greater detail. H3L-immunized mice developed high-titer vaccinia virus-neutralizing antibodies (mean PRNT50 = 1:3,760). Importantly, H3L-immunized mice were subsequently protected against lethal intranasal challenges with 1 or 5 50% lethal doses (LD50) of pathogenic vaccinia virus strain WR, demonstrating the in vivo value of an anti-H3L response. To formally demonstrate that neutralizing anti-H3L antibodies are protective in vivo, we performed anti-H3L serum passive-transfer experiments. Mice receiving H3L-neutralizing antiserum were protected from a lethal challenge with 3 LD50 of vaccinia virus strain WR (5/10 versus 0/10; P < 0.02) [PubMed: 16140750]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010764 .

obo:VO_0016513 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Gen Vax] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015982 .

obo:VO_0020718 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 660000000 CFU [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020717 .

obo:VO_0020652 a rdfs:Class ;
  rdfs:label "1 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution [Varilrix] Box of 10 by European" ;
  rdfs:subClassOf obo:VO_0020651 .

obo:VO_0002092 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002413 , obo:VO_0007748 .

obo:VO_0000309 a rdfs:Class ;
  rdfs:label "obsolete vaccine-induced antibody mediated immune response" .

obo:VO_0017320 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000942 , obo:VO_0017808 , obo:VO_0020836 .

obo:VO_0005299 a rdfs:Class ;
  rdfs:label "AlT4 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0019168 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Decavac]" ;
  rdfs:subClassOf obo:VO_0019167 , obo:VO_0019458 .

obo:VO_0007580 a rdfs:Class ;
  rdfs:label "autologous monocyte-derived mature DCs pulsed with p53, survivin and telomerase-derived peptide vaccine" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:NCBITaxon_1335626 a rdfs:Class ;
  rdfs:label "Middle East respiratory syndrome-related coronavirus" ;
  rdfs:subClassOf obo:NCBITaxon_694002 .

obo:VO_0000122 a rdfs:Class ;
  rdfs:label "Yellow fever 17D vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses Yellow fever vaccine strain 17D as the vector." ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0003695 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003693 .

obo:NCBITaxon_11050 a rdfs:Class ;
  rdfs:label "Flaviviridae" ;
  rdfs:subClassOf obo:NCBITaxon_2732406 .

obo:VO_0017769 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated Injectable Solution [Tussoglobin]" ;
  rdfs:subClassOf obo:VO_0017806 .

obo:VO_0016281 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Veron" ;
  rdfs:subClassOf obo:VO_0015924 .

obo:VO_0017575 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur] Box of 2" ;
  rdfs:subClassOf obo:VO_0017573 , obo:VO_0017577 .

obo:VO_0011033 a rdfs:Class ;
  rdfs:label "Prn" ;
  rdfs:comment "Researchers constructed isogenic mutants of B. pertussis Tohama expressing the alleles ptxA1 or ptxA2 and prn1 or prn2 and compared the efficacies of an acellular pertussis vaccine against the mutants in a mouse model. While the vaccine was effective against all of the B. pertussis strains regardless of the allele expression pattern, the strain expressing ptxA1 and prn2 displayed a survival advantage over the other strains [PubMed: 20357056]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:VO_0021102 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/11/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Delaware/55/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML / influenza B virus B/Singapore/WUH4618/2021 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020335 .

obo:VO_0016334 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0015859 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 .

obo:VO_0004061 a rdfs:Class ;
  rdfs:label "Helicobacter pylori HspB Protein vaccine" ;
  rdfs:subClassOf obo:VO_0012181 .

obo:VO_0004840 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0004836 .

obo:VO_0018262 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injectable Solution [Rabivac]" ;
  rdfs:subClassOf obo:VO_0003107 , obo:VO_0018270 .

obo:VO_0001544 a rdfs:Class ;
  rdfs:label "Feline Infectious Peritonitis Modified Live Virus Vaccine (USDA: 15A1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001220 , obo:VO_0001504 , obo:VO_0007748 .

obo:VO_0002254 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4845.23)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002429 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0017790 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 15000000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010435 .

obo:VO_0000312 a rdfs:Class ;
  rdfs:label "Brucella melitensis LPS-GBOMP noncovalent complex vaccine" ;
  rdfs:subClassOf obo:VO_0001223 .

obo:VO_0003963 a rdfs:Class ;
  rdfs:label "Vaxchora 1,200,000,000 UNT per 100 ML Oral Suspension" ;
  rdfs:subClassOf obo:VO_0003962 .

obo:VO_0015199 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015197 .

obo:VO_0019224 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020327 .

obo:VO_0002981 a rdfs:Class ;
  rdfs:label "influenza virus NS1 mutant vaccine" ;
  rdfs:comment "Intranasal inoculation of mice, pigs, horses, and macaques with NS1-modified influenza virus strains induced robust humoral and cellular immune responses, and generated immune protection against challenge with wild-type virus" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0021141 a rdfs:Class ;
  rdfs:label "influenza virus vaccine 2016-2017 (trivalent - California/Hong Kong/Brisbane) 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010432 .

obo:VO_0015216 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015306 .

obo:VO_0020129 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML Injectable Solution [Meningovax-AC]" ;
  rdfs:subClassOf obo:VO_0020128 .

obo:VO_0019136 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019960 .

obo:VO_0005076 a rdfs:Class ;
  rdfs:label "pRSC DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pRSC." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019652 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Flulaval Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020343 .

obo:VO_0000646 a rdfs:Class ;
  rdfs:label "Hepatitis A virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Hepatitis A virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003548 .

obo:VO_0017265 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adacel]" ;
  rdfs:subClassOf obo:VO_0017231 , obo:VO_0017264 .

obo:VO_0001047 a rdfs:Class ;
  rdfs:label "simian adenovirus ChAd63 vaccine vector" ;
  rdfs:comment "an adenovirus vaccine vector that uses the simian adenovirus ChAd63 strain." ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0018378 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003346 .

obo:VO_0004609 a rdfs:Class ;
  rdfs:label "pCR3.1-VS-HSP65-TP-GRP6-M2 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0006040 a rdfs:Class ;
  rdfs:label "Novel influenza-H1N1-09 preservative-free injectable" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0010415 .

obo:VO_0005036 a rdfs:Class ;
  rdfs:label "pMV10.1 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pMV10.1.  This plasmid contains a CMV promoter and a kanamycin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0018497 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0018464 .

obo:VO_0019494 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.07 MG/ML Injection [Hiberix]" ;
  rdfs:subClassOf obo:VO_0010715 , obo:VO_0019493 .

obo:VO_0018860 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0001135 a rdfs:Class ;
  rdfs:label "live attenuated Brucella melitensis vaccine" ;
  rdfs:comment "live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella melitensis infection." ;
  rdfs:subClassOf obo:VO_0000709 , obo:VO_0001127 .

obo:VO_0020724 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Solution [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020722 , obo:VO_0020723 , obo:VO_0020736 .

obo:OPL_0000040 a rdfs:Class ;
  rdfs:label "Homo sapiens hepatocyte" ;
  rdfs:comment "A hepatocyte that is a part of or originated from a human (Homo sapiens)." ;
  rdfs:subClassOf obo:CL_0000182 , obo:OPL_0000312 .

obo:VO_0016368 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Gerke" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0010140 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, tris-sucrose, 30 mcg/0.3 mL dose" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000455 , obo:VO_0005267 .

obo:VO_0015585 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [VACCIN GENHEVAC B]" ;
  rdfs:subClassOf obo:VO_0015543 , obo:VO_0015598 .

obo:VO_0001623 a rdfs:Class ;
  rdfs:label "Bronchitis Mass & Conn Types, Live Virus Vaccine (USDA:1231.1N)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0010855 a rdfs:Class ;
  rdfs:label "Helicobacter pylori protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0010913 a rdfs:Class ;
  rdfs:label "YscF from Y. pestis CO92" ;
  rdfs:comment "Ten mice were inoculated subcutaneously, administered booster injections after one month, and challenged with 130 LD(50) of wild type Y. pestis CO92.  The vaccinated animals produced high levels of specific antibodies against YscF as determined by Western blot. The data were statistically significant (P = 0.053 by two-tailed Fisher's test), suggesting that the YscF protein can provide a protective immune response against lethal plague challenge during subcutaneous plague infection [PubMed: 15939303]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0015048 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 25000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0000069 .

obo:VO_0003649 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010431 .

obo:VO_0012371 a rdfs:Class ;
  rdfs:label "PE20" ;
  rdfs:comment "A selection of previously identified protective Mycobacterium tuberculosis DNA vaccines were re-formulated as proteins and administered with a Th1-inducing adjuvant to help stimulate the relevant immune responses necessary for protection. One candidate (Rv1806-1807) induced protection in the guinea pig aerosol infection model 30 days post-challenge on the basis of reducing the bacterial burden of M. tuberculosis in the lungs [PubMed: 16520093]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0017160 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Pediacel] Box of 20" ;
  rdfs:subClassOf obo:VO_0017157 , obo:VO_0017185 , obo:VO_0017615 .

obo:VO_0007240 a rdfs:Class ;
  rdfs:label "ALVAC vaccine" ;
  rdfs:comment "A derivative of the Canarypox Virus, ALVAC can infect mammalian cells but it can't replicate. Thus, it produces a self-limiting infection which does not produce symptoms or harm the host. When carrying foreign genes it will cause transient expression of protein." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0015121 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015282 , obo:VO_0019175 .

obo:VO_0017596 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [T Wellcovax] Box of 1" ;
  rdfs:subClassOf obo:VO_0017595 , obo:VO_0017603 .

obo:VO_0000288 a rdfs:Class ;
  rdfs:label "vaccine-induced response" ;
  rdfs:comment "Process that specifies the organism's response to an administered vaccine." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OPL_0000293 a rdfs:Class ;
  rdfs:label "Plasmodium erythrocytic merozoite stage" ;
  rdfs:comment "An erythrocytic merozoite stage in the Plasmodium lifecycle that occurs in the bloodstream of a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000248 , obo:OPL_0000292 .

obo:VO_0015673 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015593 .

obo:VO_0001397 a rdfs:Class ;
  rdfs:label "vaccine containing DNA vaccine for priming and subunit vaccine for boosting" ;
  rdfs:comment "a prime-boost vaccine with DNA vaccine priming that contains a subunit vaccine for boosting" ;
  rdfs:subClassOf obo:VO_0000401 , obo:VO_0000534 .

obo:VO_0004569 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis DNA vaccine P3A" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000053 .

obo:VO_0005129 a rdfs:Class ;
  rdfs:label "UV-Inactivated SARS vaccine" ;
  rdfs:comment "A SARS inactivated vaccine made from SARS-CoV inactivated by ultraviolet radiation" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0012183 .

obo:VO_0019702 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003616 , obo:VO_0010427 .

obo:VO_0020630 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020616 .

obo:NCBITaxon_950 a rdfs:Class ;
  rdfs:label "Neorickettsia risticii" ;
  rdfs:subClassOf obo:NCBITaxon_766 .

obo:VO_0012187 a rdfs:Class ;
  rdfs:label "Clostridium botulinum vaccine" ;
  rdfs:comment "A vaccine that protects against Clostridium botulinum ." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000639 .

obo:VO_0016820 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 2" ;
  rdfs:subClassOf obo:VO_0016733 , obo:VO_0016769 .

obo:VO_0010083 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi TsF" ;
  rdfs:comment "A TsF protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0016894 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adacel] Box of 5" ;
  rdfs:subClassOf obo:VO_0016893 , obo:VO_0016895 , obo:VO_0017266 .

obo:VO_0011289 a rdfs:Class ;
  rdfs:label "T. cruzi amastigote surface protein-2" ;
  rdfs:comment "To examine the efficacy of a new mode of recombinant viral vaccine, a vaccine was constructed of two non-transmissible Sendai viruses (rSeV/dF) encoding the full-length parasite antigen amastigote surface protein-2 (ASP2) or ASP2 fused with a mono-ubiquitin on its N-terminus (UASP2). C57BL/6 mice immunized intranasally with rSeV/dF expressing either ASP2 or UASP2 showed significantly suppressed parasitemia and could be protected from lethal T. cruzi challenge [PubMed: 19712768]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0003710 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003708 .

obo:IAO_8000011 a rdfs:Class ;
  rdfs:label "external import ontology module"@en ;
  rdfs:comment "An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach."@en ;
  rdfs:subClassOf obo:IAO_8000005 .

obo:VO_0018661 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0003302 .

obo:VO_0002048 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C2.50)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0018898 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0016117 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015872 .

obo:VO_0011212 a rdfs:Class ;
  rdfs:label "MSP1 from P. yoelii str. 17XNL" ;
  rdfs:comment "Researchers found that the cysteine-rich, carboxyl-terminal region of the MSP-1 protein from the rodent malarial parasite Plasmodium yoelii yoelii can be expressed in a native configuration as a fusion protein in Escherichia coli. This recombinant polypeptide elicits antibodies in mice which recognize the native parasite MSP-1. Most significantly, both inbred and outbred mice immunized with the fusion protein in Ribi adjuvant are partially and in some cases completely protected against challenge infection with an otherwise lethal parasite strain [PubMed: 8363656]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015474 .

obo:VO_0000886 a rdfs:Class ;
  rdfs:label "oral route" ;
  rdfs:comment "A route of administration that located in the mouth" ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0017174 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] Box of 20" ;
  rdfs:subClassOf obo:VO_0017171 , obo:VO_0017185 , obo:VO_0017622 .

obo:VO_0003565 a rdfs:Class ;
  rdfs:label "PNEUMOVAX 23 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003564 .

obo:VO_0018389 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Injectable Solution [Prevnar]" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:VO_0019241 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:VO_0003340 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0002000 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:UBERON_0000106 a rdfs:Class ;
  rdfs:label "zygote stage" ;
  rdfs:comment "A stage at which the organism is a single cell produced by means of sexual reproduction." ;
  rdfs:seeAlso obo:EMAPA_16033 ;
  rdfs:subClassOf obo:UBERON_0000105 .

obo:VO_0011392 a rdfs:Class ;
  rdfs:label "Marek's Disease Virus Vaccine rFPV/gI" ;
  rdfs:subClassOf obo:VO_0012162 .

obo:VO_0018639 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injectable Suspension [Japanese encephalitis GCVC]" ;
  rdfs:subClassOf obo:VO_0018800 .

obo:VO_0016758 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.5 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016692 .

obo:VO_0019901 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluarix 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020317 .

obo:VO_0018238 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0018237 .

obo:VO_0016130 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015881 .

obo:VO_0016303 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015926 .

obo:VO_0020709 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution Box of 6" ;
  rdfs:subClassOf obo:VO_0020702 .

obo:VO_0015602 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0015555 .

obo:VO_0017683 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0010234 a rdfs:Class ;
  rdfs:label "host lineage variable" ;
  rdfs:comment "A variable representing the lineage (breed, ethnicity) of the animal host" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0017820 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017812 .

obo:VO_0017875 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0020155 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0017673 .

obo:VO_0005415 a rdfs:Class ;
  rdfs:label "mRNA-1273.214 vaccine" ;
  rdfs:comment "A SARS-CoV-2 bivalent mRNA vaccine by Moderna that contains the mRNA-1273 COVID-19 vaccine and the mRNA-1273.214 Omicron booster" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0010920 a rdfs:Class ;
  rdfs:label "TRAP from P. falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0016969 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 50 LFU/ML / Pertussis Vaccine 24 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 160 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution by Aventis" ;
  rdfs:subClassOf obo:VO_0016968 .

obo:VO_0020640 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe [Zostavax] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020638 .

obo:VO_0003684 a rdfs:Class ;
  rdfs:label "Fluvirin 2016-2017 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003682 .

obo:OGG_3001197075 a rdfs:Class ;
  rdfs:label "BMEI1364" ;
  rdfs:comment "transcriptional regulatory protein MUCR" ;
  rdfs:subClassOf obo:OGG_2060224914 .

obo:VO_0019235 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Delaware/39/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Nebraska/14/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020333 .

obo:VO_0010216 a rdfs:Class ;
  rdfs:label "Respiratory syncytial virus (RSV) monoclonal antibody (MAB), unspecified" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000753 .

obo:VO_0019179 a rdfs:Class ;
  rdfs:label "0.5 ML hepatitis B surface antigen vaccine 0.04 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0015498 .

obo:VO_0020828 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML Injectable Solution [HibTITER]" ;
  rdfs:subClassOf obo:VO_0020819 , obo:VO_0020827 .

obo:VO_0016345 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Gerke" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:VO_0019421 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.069 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.0016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.0032 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.0064 MG/ML / diphtheria toxoid vaccine, inactivated 18 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension [ACEL-IMUNE]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017799 .

obo:VO_0005396 a rdfs:Class ;
  rdfs:label "EgyVax vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Eva Pharma." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005201 .

obo:VO_0003598 a rdfs:Class ;
  rdfs:label "Fluzone 2018-2019 high-dose vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003597 .

obo:VO_0017276 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017230 .

obo:VO_0002452 a rdfs:Class ;
  rdfs:label "Mink Enteritis Vaccine-Clostridium Botulinum Type C-Pseudomonas Aeruginosa Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000393 , obo:VO_0002451 .

obo:VO_0004252 a rdfs:Class ;
  rdfs:label "Yersinia pestis F1 antigen vaccine with Flagellin" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0007591 a rdfs:Class ;
  rdfs:label "Canvaxin" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0002483 a rdfs:Class ;
  rdfs:label "horse Encephalomyelitis-Influenza-West Nile Virus vaccine" ;
  rdfs:comment "A horse vaccine that protects against EEE, VEE, WEE, influenza virius infection, and West Nile virus infection. " ;
  rdfs:subClassOf obo:VO_0000752 , obo:VO_0001472 , obo:VO_0001498 , obo:VO_0001499 , obo:VO_0012188 .

obo:VO_0015979 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25" ;
  rdfs:subClassOf obo:VO_0003264 .

obo:VO_0002059 a rdfs:Class ;
  rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.30)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002385 , obo:VO_0007748 .

obo:VO_0016679 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML [Pediacel]" ;
  rdfs:subClassOf obo:VO_0016705 .

obo:VO_0007454 a rdfs:Class ;
  rdfs:label "human papillomavirus  16 E7:12-20 peptide vaccine" ;
  rdfs:comment "A peptide based vaccine consisting of amino acids 12 through 20 of the E7 gene of the Human Papilloma Virus type 16. HPV-16 E7 12-20 peptide vaccine may elicit a specific CD8 T-cell response to the E7 oncogene protein, thereby inhibiting the abrogation of p53 and pRb function and thus prevent tumorigenesis." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0007029 a rdfs:Class ;
  rdfs:label "ONYX-015 vaccine" ;
  rdfs:comment "An E1B-55kDa-deleted adenovirus that is able to selectively replicate in and lyse TP53-deficient human tumor cells. After tumor cell lysis, released viruses infect neighboring tumor cells, tripping a chain of ONYX-015-mediated tumor cell cytotoxicity." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005497 , obo:VO_0007657 .

obo:VO_0017524 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] Box of 25" ;
  rdfs:subClassOf obo:VO_0017522 , obo:VO_0017527 .

obo:VO_0004124 a rdfs:Class ;
  rdfs:label "deltaphoP/Q Salmonella typhimurium strains expressing PEB1-ss vaccine" ;
  rdfs:subClassOf obo:VO_0012182 .

obo:VO_0017603 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0015140 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015139 , obo:VO_0015307 .

obo:VO_0015205 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015283 , obo:VO_0019362 .

obo:VO_0005344 a rdfs:Class ;
  rdfs:label "COVIDITY vaccine" ;
  rdfs:comment "A SARS-CoV-2 DNA vaccine developed by Scancell Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0018132 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain / mumps virus vaccine live, Jeryl Lynn strain / rubella virus vaccine live (Wistar RA 27-3 strain) Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018129 .

obo:VO_0012358 a rdfs:Class ;
  rdfs:label "Treponema pallidum protein" ;
  rdfs:subClassOf obo:VO_0010751 .

obo:OPL_0000389 a rdfs:Class ;
  rdfs:label "Plasmodium chabaudi sporozoite" ;
  rdfs:comment "A Plasmodium chabaudi in sporozoite stage." ;
  rdfs:subClassOf obo:NCBITaxon_5825 , obo:OPL_0000278 .

obo:VO_0015061 a rdfs:Class ;
  rdfs:label "drug dose form" ;
  rdfs:comment "A material entity of a drug based on their general physical form and how they are administered." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0020274 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [TE Anatoxal Berna]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0000938 a rdfs:Class ;
  rdfs:label "xanthan gum vaccine ajuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is derived from Xanthomonas campestris, has a pentasaccharide repeating unit structure, and its terminus contains a mannose moiety which acts as a toll-like receptor 2 agonist." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0010888 a rdfs:Class ;
  rdfs:label "TC0767 hypothetical protein" ;
  rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0767/768 showed significant levels of protection when compared to negative control animals [PubMed: 17239501]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010795 .

obo:VO_0019114 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus (H3N2) antigen 0.03 MG/ML / influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019640 .

obo:VO_0003139 a rdfs:Class ;
  rdfs:label "Stamaril vaccine" ;
  rdfs:comment "It is live attenuated YFV vaccine strain 17D manufactured in China, France, Senegal, and the USA. In powder and solvent for suspension for injection in pre-filled syringe." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003134 .

obo:VO_0016726 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0016711 , obo:VO_0016733 .

obo:VO_0000051 a rdfs:Class ;
  rdfs:label "Balb/c mouse" ;
  rdfs:subClassOf obo:NCBITaxon_10090 .

obo:VO_0016790 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016733 .

obo:VO_0002311 a rdfs:Class ;
  rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49F6.24)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002464 , obo:VO_0007748 .

obo:VO_0000117 a rdfs:Class ;
  rdfs:label "pCdm7 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016357 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:VO_0002570 a rdfs:Class ;
  rdfs:label "purE from B. melitensis" ;
  rdfs:comment "Mice infected with delta purE201 developed only five to eight times normal spleen weight at 1 week p.i. and produced no interleukin-6 in their serum, which is much lower than the mice infected with the parental strain (16M)" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001400 .

obo:IAO_0000007 a rdfs:Class ;
  rdfs:label "action specification"@en ;
  rdfs:comment "A directive information entity that describes an action the bearer will take."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:VO_0002514 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii vaccine" ;
  rdfs:comment "a malaria vaccine that protects against malaria caused by Plasmodium yoelii." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000761 .

obo:VO_0015188 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015179 , obo:VO_0015272 .

obo:VO_0015711 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015571 , obo:VO_0015788 .

obo:VO_0018689 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML Oral Suspension [Rotarix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018688 , obo:VO_0018690 .

obo:VO_0001630 a rdfs:Class ;
  rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1233.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0020563 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Stada] Box of 10 by Mylan" ;
  rdfs:subClassOf obo:VO_0020562 .

obo:VO_0011533 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum DNA vaccine encoding TC0439" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012176 .

obo:VO_0020023 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injectable Suspension [Flulaval 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020019 , obo:VO_0020337 .

obo:VO_0002489 a rdfs:Class ;
  rdfs:label "Bovine Respiratory Syncytial Virus Virus Vaccine-Haemophilus somnus Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0001466 , obo:VO_0001507 , obo:VO_0003535 .

obo:VO_0005025 a rdfs:Class ;
  rdfs:label "pABB-CRS2 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pABB-CRS2.  This plasmid is a derivative of pCVD442 and contains a chloramphenicol resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002219 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46B9.21)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002399 , obo:VO_0007748 .

obo:VO_0007121 a rdfs:Class ;
  rdfs:label "Vaccinia-GM-CSF vaccine" ;
  rdfs:comment "A recombinant vaccinia virus that encodes granulocyte-macrophage colony stimulating factor (GM-CSF). By activating T-cells and macrophages, vaccination with recombinant vaccinia GM-CSF may enhance the host immune system response to poorly immunogenic tumors, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0003918 a rdfs:Class ;
  rdfs:label "FLUAD 2015-2016 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003916 .

obo:VO_0007574 a rdfs:Class ;
  rdfs:label "Alpha Fetoprotein Plasmid DNA vaccine" ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007660 .

obo:NCBITaxon_11096 a rdfs:Class ;
  rdfs:label "Classical swine fever virus" ;
  rdfs:subClassOf obo:NCBITaxon_11095 .

obo:VO_0004112 a rdfs:Class ;
  rdfs:label "Live attenuated VEE vaccines" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0001220 , obo:VO_0001499 .

obo:VO_0010309 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003501 , obo:VO_0010299 .

obo:VO_0010967 a rdfs:Class ;
  rdfs:label "IalB" ;
  rdfs:comment "Brucella IalB is a protective antigen [PubMed: 17049676]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0017412 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017359 , obo:VO_0017411 .

obo:VO_0020403 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 10000000000 UNT Oral Powder [Vivotif] by Berna Biotech" ;
  rdfs:subClassOf obo:VO_0020376 .

obo:VO_0000457 a rdfs:Class ;
  rdfs:label "protective antigen role" ;
  rdfs:comment "An antigen that stimulates protective immunity when used in vivo." ;
  rdfs:subClassOf obo:OBI_0000237 .

obo:VO_0007154 a rdfs:Class ;
  rdfs:label "PSA/PSMA DNA Plasmid INO-5150 vaccine" ;
  rdfs:comment "A plasmid DNA vaccine encoding the tumor-associated antigens (TAAs) prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA), with potential immunoactivating and antineoplastic activities. Upon intramuscular delivery and electroporation of the PSA/PSMA DNA plasmid INO-5150, both PSA and PSMA are translated in cells which then activate the immune system. This induces cytotoxic T-lymphocyte (CTL) responses against tumor cells expressing PSA and PSMA. This may result in both immune-mediated tumor cell death and the inhibition of tumor cell proliferation. PSA and PSMA are overexpressed on a variety of cancer cell types. The DNA encoding the TAAs in INO-5150 is based on both human and other primate antigen gene sequences. As the plasmid genes differ from the human gene sequences encoding these antigens, INO-5150 may overcome immune tolerance to human TAAs." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:OPL_0000181 a rdfs:Class ;
  rdfs:label "parasite lifecycle stage" ;
  rdfs:comment "A life cycle stage of a parasite." ;
  rdfs:subClassOf obo:UBERON_0000105 .

obo:VO_0004149 a rdfs:Class ;
  rdfs:label "Recombinant vaccinia A27L, D8L, and B5R Proteins with adjuvant MPL-TDM" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000651 , obo:VO_0003060 .

obo:DOID_3905 a rdfs:Class ;
  rdfs:label "lung carcinoma"@en ;
  rdfs:comment "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis."@en ;
  rdfs:subClassOf obo:DOID_1324 , obo:DOID_305 .

obo:VO_0004306 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine d1TTFC-NP encoding NP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0015177 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0015176 , obo:VO_0015233 , obo:VO_0015264 .

obo:VO_0017773 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0017770 .

obo:VO_0001566 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.B0)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0000987 , obo:VO_0001220 .

obo:VO_0003941 a rdfs:Class ;
  rdfs:label "Human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine" ;
  rdfs:subClassOf obo:VO_0003302 .

obo:VO_0016085 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 20 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015870 .

obo:VO_0002704 a rdfs:Class ;
  rdfs:label "E2 gene from Classical swine fever virus" ;
  rdfs:comment "A E2 mutant in Classical swine fever virus is attenuated and provides protection in pigs after oronasal vaccination (not intradermal vaccination) against lethal challenge dose of CSFV strain Eystrup" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001430 .

obo:VO_0006062 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 30 mcg/0.3mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0016256 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015918 .

obo:VO_0016361 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:VO_0020856 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluad]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020890 .

obo:NCBITaxon_12845 a rdfs:Class ;
  rdfs:label "Swine influenza virus" ;
  rdfs:subClassOf obo:NCBITaxon_35324 .

obo:NCBITaxon_29486 a rdfs:Class ;
  rdfs:label "Yersinia ruckeri" ;
  rdfs:subClassOf obo:NCBITaxon_629 .

obo:VO_0019580 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020493 .

obo:NCBITaxon_1491 a rdfs:Class ;
  rdfs:label "Clostridium botulinum" ;
  rdfs:subClassOf obo:NCBITaxon_1485 .

obo:VO_0002674 a rdfs:Class ;
  rdfs:label "envZ from Shigella" ;
  rdfs:comment "An envZ mutant (SC433) is greatly decreased in virulence in macaque monkeys, though some mild clinical signs were still recorded. This mutant is also highly protective against a challenge of wild type S. flexneri delivered 1 month after inoculation" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000169 .

obo:VO_0018451 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML Injectable Solution [Pnu-Imune] by Lederle Products" ;
  rdfs:subClassOf obo:VO_0018420 .

obo:VO_0001820 a rdfs:Class ;
  rdfs:label "Bordetella Avium Avirulent Live Culture Vaccine (USDA: 1021.01)" ;
  rdfs:subClassOf obo:VO_0000125 , obo:VO_0000455 , obo:VO_0001114 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0018121 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella virus vaccine Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018118 .

obo:VO_0003876 a rdfs:Class ;
  rdfs:label "Flublok 2012-2013 Formula Influenza Virus Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003875 .

obo:VO_0001970 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1187.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0016170 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 20 by Merck" ;
  rdfs:subClassOf obo:VO_0016004 .

obo:VO_0012360 a rdfs:Class ;
  rdfs:label "OprF" ;
  rdfs:comment "The oprF gene was cloned into plasmid vector pVR1020, and the plasmid vaccines were delivered to mice by biolistic (gene gun) intradermal inoculation. Following the initial immunization and two consecutive boosts, each at 2-week intervals, protection was demonstrated in a mouse model of chronic pulmonary infection by P. aeruginosa. Eight days postchallenge, both lungs were removed and examined. A significant reduction in the presence of severe macroscopic lesions, as well as in the number of bacteria present in the lungs, was seen [PubMed: 11292786]." ;
  rdfs:subClassOf obo:VO_0012370 .

obo:VO_0004818 a rdfs:Class ;
  rdfs:label "Rotarix, Rotavirus, live attenuated (RV1) G1P[8] Oral Vaccine" ;
  rdfs:subClassOf obo:VO_0004819 .

obo:VO_0002793 a rdfs:Class ;
  rdfs:label "atherosclerosis vaccine" ;
  rdfs:comment "A vaccine that prevents or treats atherosclerosis disease." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005503 .

obo:VO_0016559 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0016557 .

obo:VO_0019111 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML Prefilled Syringe [Fluzone Intradermal 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0010418 , obo:VO_0019110 .

obo:GO_0071745 a rdfs:Class ;
  rdfs:label "IgA immunoglobulin complex" ;
  rdfs:comment "A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ;
  rdfs:subClassOf obo:GO_0019814 .

obo:VO_0000897 a rdfs:Class ;
  rdfs:label "age at vaccination" ;
  rdfs:comment "Age at vaccination is the age of an experiment animal at the time of vaccination." ;
  rdfs:subClassOf obo:PATO_0000011 .

obo:VO_0000040 a rdfs:Class ;
  rdfs:label "pBC12/CMV DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019899 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Afluria 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020301 .

obo:VO_0019522 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.005 MG/ML [Recombivax]" ;
  rdfs:subClassOf obo:VO_0003257 .

obo:VO_0004705 a rdfs:Class ;
  rdfs:label "poliovirus vector expressing model antigen H2-Kb-restricted CTL epitope vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0010003 a rdfs:Class ;
  rdfs:label "Cp60 from Crptosporidium parvum" ;
  rdfs:comment "A CP60 protein that is part of Crptosporidium parvum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010842 .

obo:VO_0020435 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Waymade" ;
  rdfs:subClassOf obo:VO_0020410 .

obo:VO_0004399 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum recombinant vector vaccine MVA.ME-TRAP" ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000484 .

obo:VO_0007066 a rdfs:Class ;
  rdfs:label "Verpasep Caltespen Vaccine" ;
  rdfs:comment "A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers. E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005488 , obo:VO_0007657 .

obo:VO_0006045 a rdfs:Class ;
  rdfs:label "rabies vaccine for intradermal injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010448 .

obo:VO_0011223 a rdfs:Class ;
  rdfs:label "PF10_0155 enolase" ;
  rdfs:comment "Mice immunized with r-Pfen (recombinant P. falciparum enolase protein) showed protection against a challenge with the 17XL lethal strain of the mouse malarial parasite Plasmodium yoelii [PubMed: 17785475]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015474 .

obo:VO_0011129 a rdfs:Class ;
  rdfs:label "NA from Influenza B virus (B/Ibaraki/2/85)" ;
  rdfs:comment "Protection against a lethal influenza B virus infection was examined in BALB/c mice immunized with plasmid DNAs encoding hemagglutinin (HA), neuraminidase (NA and NB) and nucleoprotein (NP) from the B/Ibaraki/2/85 virus.  Both HA and NA DNAs conferred complete protection against the lethal challenge in all the tested mouse strains [PubMed: 11163667]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:DOID_863 a rdfs:Class ;
  rdfs:label "nervous system disease"@en ;
  rdfs:comment "A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system."@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:VO_0007631 a rdfs:Class ;
  rdfs:label "L612 HuMAb vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0001561 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Killed Virus Vaccine (USDA: 1105.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0000987 .

obo:VO_0000267 a rdfs:Class ;
  rdfs:label "fungal vaccine" ;
  rdfs:comment "A vaccine that targets against a fungus infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005563 .

obo:VO_0007552 a rdfs:Class ;
  rdfs:label "host dendritic cell vaccine-001 MSSM/BIIR" ;
  rdfs:comment "A dendritic cell (DC) vaccine containing ex vivo expanded autologous DCs obtained from a patient with leukemia with potential immunostimulating activity. Upon reintroduction into the host, the host dendritic cell vaccine-001 MSSM/BIIR may stimulate the immune system to mount a leukemia-specific cytotoxic T lymphocyte (CTL) response." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:NCBITaxon_11216 a rdfs:Class ;
  rdfs:label "Human respirovirus 3" ;
  rdfs:subClassOf obo:NCBITaxon_186938 .

obo:VO_0002675 a rdfs:Class ;
  rdfs:label "icsA/virG from Shigella" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000169 .

obo:VO_0001218 a rdfs:Class ;
  rdfs:label "veterinary vaccine" ;
  rdfs:comment "Vaccine that is used for animals (excluding humans), for example, pet, domestic, wildlife, and livestock animals." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0019638 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2023 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020496 .

obo:VO_0001894 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4209.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002342 .

obo:VO_0004652 a rdfs:Class ;
  rdfs:label "BV-Dual-S1 vaccine" ;
  rdfs:subClassOf obo:VO_0001497 .

obo:VO_0011544 a rdfs:Class ;
  rdfs:label "Streptococcus equi Subunit EAG, FNZ and SFS protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000948 .

obo:VO_0018411 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 5 vaccine 0.001 MG" ;
  rdfs:subClassOf obo:VO_0003255 .

obo:VO_0019217 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/11/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Delaware/55/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML / influenza B virus B/Singapore/WUH4618/2021 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0015871 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 50" ;
  rdfs:subClassOf obo:VO_0015614 , obo:VO_0015693 , obo:VO_0015996 .

obo:VO_0000588 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis phoP mutant SO2 vaccine" ;
  rdfs:comment "Study evaluated immunogenicity and protection against Mycobacterium tuberculosis in rhesus monkeys with an attenuated M. tuberculosis with a disrupted phoP gene (SO2) as a single-dose vaccine. SO2 treatment showed reduced average lung bacterial counts (1.0 and 1.2 log respectively, compared with 0.4 log for BCG) and significant protective effect by reduction in C-reactive protein levels, body weight loss, and decrease of erythrocyte-associated hematologic parameters (MCV, MCH, Hb, Ht) as markers of inflammatory infection, all relative to non-vaccinated controls" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0017628 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0017610 .

obo:VO_0018496 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018463 .

obo:IAO_0000088 a rdfs:Class ;
  rdfs:label "report"@en ;
  rdfs:comment "A document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record)."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:VO_0015640 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [H B Vax]" ;
  rdfs:subClassOf obo:VO_0015574 , obo:VO_0015669 .

obo:VO_0010483 a rdfs:Class ;
  rdfs:label "licensed human Hantavirus vaccine" ;
  rdfs:comment "Hantavirus vaccine that is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0012167 .

obo:VO_0002147 a rdfs:Class ;
  rdfs:label "Marek's Disease-Tenosynovitis Serotypes 2 & 3, Live Virus Vaccine (USDA: 16T1.03)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001019 , obo:VO_0002448 , obo:VO_0007748 .

obo:VO_0020156 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0020155 .

obo:VO_0002507 a rdfs:Class ;
  rdfs:label "Salmonella typhimurium vaccine" ;
  rdfs:comment "A bacterial vaccine that protects against infections by  Salmonella typhimurium species." ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0020704 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] Box of 3" ;
  rdfs:subClassOf obo:VO_0020703 , obo:VO_0020707 .

obo:VO_0004113 a rdfs:Class ;
  rdfs:label "live attenuated V3526 virus vaccine" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0001499 .

obo:VO_0011504 a rdfs:Class ;
  rdfs:label "Clostridium botulinum FHc protein vaccine" ;
  rdfs:subClassOf obo:VO_0012187 .

obo:VO_0018466 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0018454 .

obo:VO_0002421 a rdfs:Class ;
  rdfs:label "equine rhinopneumonitis-influenza vaccine" ;
  rdfs:subClassOf obo:VO_0001472 , obo:VO_0001486 .

obo:VO_0004381 a rdfs:Class ;
  rdfs:label "Ebola virus recombinant vector vaccine pVSVXN2-Delta-G/ZEBOVsGP encoding GP" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000726 .

obo:VO_0020037 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020028 , obo:VO_0020479 .

obo:VO_0004593 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii DNA vaccine encoding MSP1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002514 .

obo:VO_0004299 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pIRES/NA/GM-CSF encoding NA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0002049 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C2.51)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0001157 a rdfs:Class ;
  rdfs:label "E. coli O157 vaccine" ;
  rdfs:subClassOf obo:VO_0000041 .

obo:VO_0018061 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 25 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018060 .

obo:VO_0000005 a rdfs:Class ;
  rdfs:label "Adacel vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000714 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0007116 a rdfs:Class ;
  rdfs:label "TRP1(0RF3):1-9 peptide vaccine" ;
  rdfs:comment "A recombinant peptide consisting of amino acid residues 1 to 9 of the tyrosinase-related protein 1 (TRP1). Expressed by cells of melanocyte origin, TRP1 is an enzyme involved in the process that converts tyrosinase to melanin pigments. Vaccination with TRP1(0RF3):1-9 may stimulate cytotoxic T cell responses to melanoma cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0000790 a rdfs:Class ;
  rdfs:label "Brucella gene" ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0002160 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:NCBITaxon_11636 a rdfs:Class ;
  rdfs:label "Reticuloendotheliosis virus" ;
  rdfs:subClassOf obo:NCBITaxon_153135 .

obo:VO_0016805 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 10" ;
  rdfs:subClassOf obo:VO_0016727 , obo:VO_0016747 , obo:VO_0016819 .

obo:VO_0003143 a rdfs:Class ;
  rdfs:label "licensed influenza vaccine" ;
  rdfs:subClassOf obo:VO_0000363 , obo:VO_0000642 .

obo:VO_0015590 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015528 , obo:VO_0015600 .

obo:VO_0004262 a rdfs:Class ;
  rdfs:label "obsolete E. coli CS3 in PLGA microspheres" .

obo:VO_0020289 a rdfs:Class ;
  rdfs:label "Vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0006004 , obo:VO_0010312 .

obo:VO_0000441 a rdfs:Class ;
  rdfs:label "vaccine candidate role" ;
  rdfs:comment "Role of a material entity in an investigation, which has not been experimentally or clinically verified to induce a protection or treatment in vivo in a recipient organism. " ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0010279 a rdfs:Class ;
  rdfs:label "pathogen attenuation datum" ;
  rdfs:comment "A measurment datum that records the utilization of an attenaution process on a pathogen." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0016178 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:NCBITaxon_39107 a rdfs:Class ;
  rdfs:label "Murinae" ;
  rdfs:subClassOf obo:NCBITaxon_9989 .

obo:VO_0010873 a rdfs:Class ;
  rdfs:label "Lef from B. anthracis str. Ames Ancestor" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010757 .

obo:VO_0005349 a rdfs:Class ;
  rdfs:label "Covi Vax vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by the National Research Centre of Egypt" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005201 .

obo:VO_0019151 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.02 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:NCBITaxon_5763 a rdfs:Class ;
  rdfs:label "Naegleria fowleri" ;
  rdfs:subClassOf obo:NCBITaxon_5761 .

obo:VO_0001332 a rdfs:Class ;
  rdfs:label "poly(I:C) vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant containing Poly(I:C), a synthetic double stranded analog of RNA." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:CL_0000988 a rdfs:Class ;
  rdfs:label "hematopoietic cell" ;
  rdfs:comment "A cell of a hematopoietic lineage." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:VO_0019743 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2023 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020496 .

obo:NCBITaxon_5863 a rdfs:Class ;
  rdfs:label "Piroplasmida" ;
  rdfs:subClassOf obo:NCBITaxon_422676 .

obo:VO_0016546 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015984 .

obo:VO_0007341 a rdfs:Class ;
  rdfs:label "autologous neuroblastoma cell vaccine" ;
  rdfs:comment "A cancer vaccine that uses autologous neuroblastoma cells, irradiated and genetically modified by adenoviral vectors to secrete interleukin-2 (IL-2) for patients with high-risk neuroblastoma. The adenoviral vector are used to transduce the cells ex-vivo, patients are not treated with the viral vector." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0004938 a rdfs:Class ;
  rdfs:label "human age 12 to 23 months at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0002992 a rdfs:Class ;
  rdfs:label "Rabies virus P protein mutant vaccine" ;
  rdfs:comment "A P gene mutant is attenuated in mice and induces significant protection from challenge with wild type Rabies virus" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0000619 a rdfs:Class ;
  rdfs:label "E. coli live attenuated vaccine" ;
  rdfs:subClassOf obo:VO_0000041 , obo:VO_0001217 .

obo:VO_0016059 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 25" ;
  rdfs:subClassOf obo:VO_0003420 .

obo:VO_0017819 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017812 .

obo:VO_0016350 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 20 by Veron" ;
  rdfs:subClassOf obo:VO_0015940 .

obo:VO_0003992 a rdfs:Class ;
  rdfs:label "INFANRIX vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003991 .

obo:VO_0019259 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019803 .

obo:NCBITaxon_180252 a rdfs:Class ;
  rdfs:label "Mardivirus" ;
  rdfs:subClassOf obo:NCBITaxon_10293 .

obo:VO_0007313 a rdfs:Class ;
  rdfs:label "Autologous Prostate Cancer Antigen-expressing Dendritic Cell Vaccine BPX-101" ;
  rdfs:comment "A genetically-modified autologous dendritic cell-based vaccine expressing a drug-inducible costimulatory CD40 receptor (iCD40) with potential immunomodulating and antineoplastic activities. Autologous dendritic cells (DCs) are genetically modified to express the iCD40 receptor and are pulsed with the tumor antigen prostate-specific membrane antigen (PSMA). Upon intradermal administration, these DCs accumulate in local draining lymph nodes. Twenty-four hours after vaccination, the dimerizer agent AP1903 is administered; AP1903 binds to and activates iCD40 receptors presented on DC surfaces, thus activating the DCs and stimulating a cytotoxic T-lymphocyte (CTL) response against host tumor cells that express PSMA. This delayed activation strategy optimizes DC accumulation in local draining lymph nodes prior to DC activation. iCD40 contains a membrane-localized cytoplasmic CD40 domain fused to a drug-binding domain." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0000190 a rdfs:Class ;
  rdfs:label "squalene vacccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant that contains an organic polymer with some antigenic epitopes which might be shared with other organic polymers acting as immunostimulators." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0018563 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection [Typherix] Box of 10" ;
  rdfs:subClassOf obo:VO_0018562 , obo:VO_0018566 .

obo:VO_0011313 a rdfs:Class ;
  rdfs:label "G glycoprotein from Nipah virus" ;
  rdfs:comment "Hamsters were immunized subcutaneously with either 107 PFU of VV-NiV.G or VV-NiV.F expressing the G and F glycoproteins, respectively, or with the two combined.  When the VV-NiV.G-vaccinated animals were challenged with Nipah virus 3 months after the last immunization (1,000 PFU/animal intraperitoneally), there was complete protection against mortality [PubMed: 14694115]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010845 .

obo:VO_0001435 a rdfs:Class ;
  rdfs:label "Gallid herpesvirus 1 gene" ;
  rdfs:comment "A viral gene that is from Gallid herpesvirus 1." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0001646 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.18)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0015642 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015670 .

obo:VO_0002327 a rdfs:Class ;
  rdfs:label "avian encephalomyelitis-fowl pox-laryngotracheitis vaccine" ;
  rdfs:subClassOf obo:VO_0002326 , obo:VO_0002443 .

obo:VO_0004646 a rdfs:Class ;
  rdfs:label "cAdVaxM(fus) vaccine" ;
  rdfs:subClassOf obo:VO_0012163 .

obo:VO_0018511 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 1 by European" ;
  rdfs:subClassOf obo:VO_0018504 .

obo:VO_0000800 a rdfs:Class ;
  rdfs:label "vaccine storage" ;
  rdfs:comment "a storage process that is specifically for vaccine." ;
  rdfs:subClassOf obo:OBI_0302893 .

obo:VO_0011432 a rdfs:Class ;
  rdfs:label "Chlamydophila pneumoniae CopN protein vaccine" ;
  rdfs:subClassOf obo:VO_0012173 .

obo:VO_0004627 a rdfs:Class ;
  rdfs:label "Leishmania T -PpSP15 vaccine" ;
  rdfs:subClassOf obo:VO_0001231 .

obo:VO_0010173 a rdfs:Class ;
  rdfs:label "human papilloma virus vaccine, quadrivalent" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010446 .

obo:VO_0015877 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015617 , obo:VO_0016002 .

obo:VO_0017527 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017521 .

obo:VO_0019819 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0019968 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluvirin 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019949 .

obo:BFO_0000004 a rdfs:Class ;
  rdfs:label "independent continuant"@en ;
  rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:VO_0005414 a rdfs:Class ;
  rdfs:label "LVRNA009 vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine by AIM Vaccine Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0020436 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020405 .

obo:VO_0005355 a rdfs:Class ;
  rdfs:label "LTA1 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant made from the A subunit of heat-labile (LT) enterotoxin of Enterotoxigenic Escherichia coli (ETEC). This LTA1 adjuvant is able to induce Th1, Th2, and Th17 immune responses." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002081 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.43)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0001559 a rdfs:Class ;
  rdfs:label "Bovine Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1095.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001507 .

obo:VO_0001680 a rdfs:Class ;
  rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.13)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000985 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0019404 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 8 UNT/ML / diphtheria toxoid vaccine, inactivated 25 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017799 , obo:VO_0018770 .

obo:VO_0007216 a rdfs:Class ;
  rdfs:label "Algenpantucel-L Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of irradiated allogeneic pancreatic cancer cells transfected to express murine alpha-1,3-galactosyltransferase with potential antitumor activity. Vaccination is associated with the expression of murine alpha-1,3-galactosyl (alpha-gal) carbohydrate residues on cell membrane glycoproteins and glycolipids of the vaccine pancreatic cancer cell allograft; murine alpha-gal epitopes, not present on human cells, then induce a hyperacute rejection of the vaccine pancreatic cancer cell allograft. The hyperacute rejection involves the binding of pre-existing human anti-alpha-gal antibodies (which naturally occur against gut flora) to murine alpha-gal epitopes, resulting in the rapid activation of antibody-dependent cell-mediated cytotoxicity (ADCC) towards allograft cells. The host immune system then attacks endogenous pancreatic cancer cells, resulting in ADCC towards endogenous pancreatic cancer cells." ;
  rdfs:subClassOf obo:VO_0005430 , obo:VO_0007657 .

obo:OPL_0000192 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum gametocyte stage" ;
  rdfs:comment "A gametocyte stage in the lifecycle of Plasmodium falciparum." ;
  rdfs:subClassOf obo:OPL_0000150 , obo:OPL_0000165 , obo:OPL_0000289 .

obo:VO_0004098 a rdfs:Class ;
  rdfs:label "LC16m0 vaccine" ;
  rdfs:subClassOf obo:VO_0000651 .

obo:VO_0007613 a rdfs:Class ;
  rdfs:label "hMART-IT vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0003067 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000534 , obo:VO_0000556 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0003974 a rdfs:Class ;
  rdfs:label "Kinrix Injectable Product" ;
  rdfs:subClassOf obo:VO_0000067 .

obo:VO_0003452 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010306 , obo:VO_0010415 .

obo:VO_0016450 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Haematogmbh" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0001946 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.26)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0016813 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Pediacel] Box of 10" ;
  rdfs:subClassOf obo:VO_0016731 , obo:VO_0016755 , obo:VO_0016828 .

obo:VO_0001146 a rdfs:Class ;
  rdfs:label "Orthopoxvirus vaccine vector" ;
  rdfs:comment "a poxvirus vaccine vector that uses an orthopox virus as the vector" ;
  rdfs:subClassOf obo:VO_0000447 .

obo:VO_0018523 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe Box of 20" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0007330 a rdfs:Class ;
  rdfs:label "Berzofsky Ras/P53 peptide vaccine" ;
  rdfs:comment "A synthetic vaccine combining the peptide antigens of two proteins, ras oncoprotein and tumor suppressor p53" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0016267 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015923 .

obo:VO_0017342 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017341 .

obo:VO_0018691 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 700000 PFU" ;
  rdfs:subClassOf obo:VO_0004815 .

obo:VO_0002973 a rdfs:Class ;
  rdfs:label "Herpes simplex virus 1 TK mutant vaccine" ;
  rdfs:comment "A thymidine kinase-deficient (TK) mutant was found to be attenuated in mice. This mutant induced complete protection from challenge with wild type HSV" ;
  rdfs:subClassOf obo:VO_0000958 .

obo:VO_0005061 a rdfs:Class ;
  rdfs:label "nkCMVintpolyli DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label nkCMVintpolyli.  This plasmid contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015729 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015800 .

obo:VO_0020503 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0011092 a rdfs:Class ;
  rdfs:label "ANDVsSgp1" ;
  rdfs:comment "Nonreplicating adenovirus (Ad) vectors that express Andes hantavirus (ANDV) nucleocapsid protein (AdN, ANDVsSgp1) or glycoproteins (AdG(N) and AdG(C)) were constructed . When administered once, all three Ad vectors, individually or in combination, elicited a robust immune response that protected Syrian hamsters from a lethal ANDV infection that mimics the pulmonary disease seen in humans. No vaccinated animal died, and there were no obvious clinical signs of disease [PubMed: 19403663]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010768 .

obo:VO_0019459 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Tenivac]" ;
  rdfs:subClassOf obo:VO_0000102 , obo:VO_0019457 .

obo:VO_0011199 a rdfs:Class ;
  rdfs:label "SrtA" ;
  rdfs:comment "Intraperitoneal immunization with recombinant SrtA was found to have  conferred to mice protection against S. pneumoniae intraperitoneal challenge and the passive transfer of immune serum before intraperitoneal challenge was also protective. Moreover, by using the intranasal challenge model,  significant reduction of bacteremia when mice were intraperitoneally immunized with SrtA was observed, while a moderate decrease of lung infection was achieved by intranasal immunization, even though no influence on nasopharynx colonization was seen [PubMed: 19433540]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0003785 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2016-2017 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003784 .

obo:VO_0005065 a rdfs:Class ;
  rdfs:label "pCI-TPA DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCI-TPA.  This plasmid contains the N-terminal signal sequence of TPA." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019342 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML Injection [Menquadfi]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0003441 , obo:VO_0010436 , obo:VO_0010444 .

obo:BFO_0000146 a rdfs:Class ;
  rdfs:label "two-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:VO_0020466 a rdfs:Class ;
  rdfs:label "0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10 by Waymade" ;
  rdfs:subClassOf obo:VO_0020447 .

obo:VO_0010014 a rdfs:Class ;
  rdfs:label "Leishmania  donovani Beta-tubulin" ;
  rdfs:comment "A Beta-tubulin protein that is part of Leishmania  donovani" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:NCBITaxon_2611341 a rdfs:Class ;
  rdfs:label "Metamonada" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:VO_0016163 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0016003 .

obo:VO_0001854 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 16D5.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0002436 , obo:VO_0007748 .

obo:VO_0004397 a rdfs:Class ;
  rdfs:label "Brucella melitensis DNA vaccine p-ialB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000709 .

obo:NCBITaxon_2560080 a rdfs:Class ;
  rdfs:label "Rubulavirinae" ;
  rdfs:subClassOf obo:NCBITaxon_11158 .

obo:GO_0071742 a rdfs:Class ;
  rdfs:label "IgE immunoglobulin complex" ;
  rdfs:comment "A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ;
  rdfs:subClassOf obo:GO_0019814 .

obo:VO_0003351 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine Injectable Product" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0003689 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Fluvirin 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003687 .

obo:VO_0002495 a rdfs:Class ;
  rdfs:label "influenza vaccine (split virion, inactivated)" ;
  rdfs:comment """created according to 
WHO Technical Report Series, No. 927, 2005
Annex 3
Recommendations for the production and control of influenza vaccine (inactivated)""" ;
  rdfs:subClassOf obo:VO_0001176 .

obo:VO_0017704 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017685 , obo:VO_0017751 .

obo:VO_0015682 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [Hevac B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015564 , obo:VO_0015772 .

obo:VO_0019641 a rdfs:Class ;
  rdfs:label "influenza A virus (H3N2) antigen 0.03 MG/ML / influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2020 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020490 .

obo:VO_0016080 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0015869 .

obo:VO_0015505 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML [Hevac B]" ;
  rdfs:subClassOf obo:VO_0003257 .

obo:NCBITaxon_10260 a rdfs:Class ;
  rdfs:label "Avipoxvirus" ;
  rdfs:subClassOf obo:NCBITaxon_10241 .

obo:VO_0016530 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0003388 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003201 .

obo:VO_0000758 a rdfs:Class ;
  rdfs:label "Plasmodium vivax vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000761 .

obo:VO_0019140 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Fluzone 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019139 , obo:VO_0020480 .

obo:VO_0017498 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:VO_0001678 a rdfs:Class ;
  rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000985 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0011251 a rdfs:Class ;
  rdfs:label "GI" ;
  rdfs:comment "Vaccination of mice with fusion proteins containing the N terminus of gI from Suid herpesvirus 1 are able to confer protection to mice against a lethal challenge of PRV [PubMed: 1693164]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010800 .

obo:VO_0007148 a rdfs:Class ;
  rdfs:label "PROSTVAC-Contaminated W/ BVDV vaccine" ;
  rdfs:comment "A vaccinia virus carrying a copy of the human gene encoding prostate-specific antigen (PSA), contaminated with bovine viral diarrhea virus (BVDV)." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process"@en ;
  rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:VO_0015931 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015635 , obo:VO_0016036 .

obo:VO_0015848 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] by GSK" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 .

obo:VO_0004317 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 DNA vaccine pMASIAtgB encoding a truncated, secreted form of gB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000987 .

obo:VO_0020659 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] Box of 3 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020658 .

obo:VO_0006039 a rdfs:Class ;
  rdfs:label "Novel Influenza-H1N1-09 live virus for nasal administration" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001178 , obo:VO_0010415 .

obo:VO_0002918 a rdfs:Class ;
  rdfs:label "obsolete CVD 1204(pGA1-CS2)" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" .

obo:PATO_0000044 a rdfs:Class ;
  rdfs:label "frequency" ;
  rdfs:comment "A physical quality which inheres in a bearer by virtue of the number of the bearer's repetitive actions in a particular time." ;
  rdfs:subClassOf obo:PATO_0000001 .

obo:VO_0001023 a rdfs:Class ;
  rdfs:label "BCG vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector that uses TB vaccine BCG as the vector." ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0016294 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0016027 .

obo:VO_0002265 a rdfs:Class ;
  rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.21)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002420 , obo:VO_0007748 .

obo:VO_0002500 a rdfs:Class ;
  rdfs:label "Listeria monocytogenes vaccine" ;
  rdfs:comment "Vaccine that protects against Listeria monocytogenes infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003555 .

obo:VO_0010754 a rdfs:Class ;
  rdfs:label "virus protein" ;
  rdfs:comment "a protein from a virus" ;
  rdfs:subClassOf obo:PR_000000001 .

obo:NCBITaxon_9940 a rdfs:Class ;
  rdfs:label "Ovis aries" ;
  rdfs:subClassOf obo:NCBITaxon_9935 .

obo:NCBITaxon_1717 a rdfs:Class ;
  rdfs:label "Corynebacterium diphtheriae" ;
  rdfs:subClassOf obo:NCBITaxon_1716 .

obo:VO_0000725 a rdfs:Class ;
  rdfs:label "Dengue virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Dengue virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003546 .

obo:VO_0007302 a rdfs:Class ;
  rdfs:label "Autologous Lymphoma Cell Lysate-Pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous lymphoma cells with potential immunostimulatory and antineoplastic activities. Upon intranodal administration, autologous lymphoma cell lysate-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against lymphoma cells, which may result in lymphoma cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0017585 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 8 UNT/ML [Tetanol]" ;
  rdfs:subClassOf obo:VO_0003406 .

obo:VO_0004578 a rdfs:Class ;
  rdfs:label "HSV 2 DNA vaccine pVAX-HSV-2gD-HSP70" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:NCBITaxon_1781 a rdfs:Class ;
  rdfs:label "Mycobacterium marinum" ;
  rdfs:subClassOf obo:NCBITaxon_1763 .

obo:VO_0020450 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0020415 , obo:VO_0020426 .

obo:VO_0016311 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0015927 .

obo:VO_0020675 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0007391 a rdfs:Class ;
  rdfs:label "Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from malignant glioma cells with potential immunostimulatory and antineoplastic activities. Upon administration, malignant glioma tumor lysate-pulsed autologous dendritic cell vaccine exposes the immune system to undefined malignant glioma tumor-associated antigens (TAAs), which may result in anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against glioma cells and glioma cell lysis." ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0019754 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2023 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020496 .

obo:VO_0010353 a rdfs:Class ;
  rdfs:label "MenQuadfi vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0010444 .

obo:VO_0015596 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003416 .

obo:VO_0004012 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis LctP protein vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0016141 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0020548 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluad] Box of 10" ;
  rdfs:subClassOf obo:VO_0020547 , obo:VO_0020603 , obo:VO_0020857 .

obo:VO_0001600 a rdfs:Class ;
  rdfs:label "avian influenza H5N2 Subtype, Killed Virus Vaccine (USDA: 10F5.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0015059 a rdfs:Class ;
  rdfs:label "Mumps Virus Vaccine Live, Jeryl Lynn Strain 40000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010442 .

obo:VO_0001289 a rdfs:Class ;
  rdfs:label "calcium phosphate gel vaccine adjuvant" ;
  rdfs:comment "A calcium phosphate vaccine adjuvant that is a gel prepared by precipitating soluable calcium and phosphate salts." ;
  rdfs:subClassOf obo:VO_0000131 .

obo:VO_0016394 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0005502 a rdfs:Class ;
  rdfs:label "transmission-blocking vaccine" ;
  rdfs:comment "A vaccine that prevents or reduce the transmission of a disorder within a target host or among a population by inducing or modifying specific adaptive immune responses against the antigens present in the vaccine." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0002344 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Respiratory Syncytial Virus vaccine" ;
  rdfs:subClassOf obo:VO_0000987 , obo:VO_0001507 .

obo:VO_0012173 a rdfs:Class ;
  rdfs:label "Chlamydophila pneumoniae vaccine" ;
  rdfs:comment "A Chlamydia vaccine that protects against Chlamydophila pneumoniae." ;
  rdfs:subClassOf obo:VO_0000573 .

obo:VO_0007091 a rdfs:Class ;
  rdfs:label "Unconjugated Lymphoma Ig Id Vaccine" ;
  rdfs:comment "A vaccine consisting of lymphoma-specific immunoglobulin that is not conjugated to a carrier molecule. Vaccination with unconjugated lymphoma Ig Id may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against lymphoma cells, resulting in decreased tumor growth.‚Äö√†√∂‚àö¬ß" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0004476 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine pTPA-PA63" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0011368 a rdfs:Class ;
  rdfs:label "Cancer recombinant vector vaccine encoding H-2Kb" ;
  rdfs:comment "Gene name: H2-K1" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0015090 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015089 .

obo:VO_0010208 a rdfs:Class ;
  rdfs:label "poliovirus vaccine, unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 .

obo:VO_0017002 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tet Aktiv] Box of 100" ;
  rdfs:subClassOf obo:VO_0017001 , obo:VO_0017021 , obo:VO_0017488 .

obo:VO_0017373 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Di Tetasorbat]" ;
  rdfs:subClassOf obo:VO_0018786 .

obo:VO_0016483 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0018552 a rdfs:Class ;
  rdfs:label "0.5 ML Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML Injectable Solution [Mumpsvax] by Merck" ;
  rdfs:subClassOf obo:VO_0018551 .

obo:VO_0018249 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0003980 a rdfs:Class ;
  rdfs:label "KINRIX vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003979 .

obo:VO_0018745 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018715 .

obo:VO_0017063 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution [Tetamun] Box of 1" ;
  rdfs:subClassOf obo:VO_0017062 , obo:VO_0017065 , obo:VO_0017540 .

obo:NCBITaxon_11976 a rdfs:Class ;
  rdfs:label "Rabbit hemorrhagic disease virus" ;
  rdfs:subClassOf obo:NCBITaxon_11974 .

obo:VO_0017137 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 2 by Novartis" ;
  rdfs:subClassOf obo:VO_0017136 .

obo:VO_0017608 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0002894 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Gallinarum cpxR/Ion mutant vaccine" ;
  rdfs:comment "A lon mutant, in combination with a cpxR mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" .

obo:VO_0015691 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015566 , obo:VO_0015777 .

obo:VO_0019287 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0011172 a rdfs:Class ;
  rdfs:label "FbpB from M. tuberculosis" ;
  rdfs:comment "Immunization with DNA encoding Ag85B (fbpB), a candidate vaccine antigen of Mycobacterium tuberculosis, elicited in mice a low but protective CD4(+) T cell-mediated IFN-gamma response [PubMed: 20544034]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0000662 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae serotype b vaccine" ;
  rdfs:comment "A vaccine that protects against Haemophilus influenzae type b infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0012185 .

obo:VO_0011352 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus DNA vaccine pUJENS5" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000665 .

obo:VO_0017538 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML [Tetamun]" ;
  rdfs:subClassOf obo:VO_0003407 .

obo:VO_0002801 a rdfs:Class ;
  rdfs:label "Bordetella bronchiseptica aroA mutant vaccine (strain BBS18)" ;
  rdfs:comment "Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract" ;
  rdfs:subClassOf obo:VO_0000394 .

obo:VO_0017694 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Pediacel] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017693 .

obo:VO_0018281 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injection [Rabipur]" ;
  rdfs:subClassOf obo:VO_0018806 .

obo:VO_0003229 a rdfs:Class ;
  rdfs:label "obsolete Hepatitis A virus-Typhoid vaccine" .

obo:NCBITaxon_204722 a rdfs:Class ;
  rdfs:label "Brucella suis 1330" ;
  rdfs:subClassOf obo:NCBITaxon_29461 .

obo:VO_0011487 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni FspA2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012182 .

obo:VO_0001577 a rdfs:Class ;
  rdfs:label "Brucella Abortus Strain RB-51, Live Culture Vaccine (USDA: 1261.00)" ;
  rdfs:subClassOf obo:VO_0000021 , obo:VO_0000813 , obo:VO_0001214 .

obo:VO_0011509 a rdfs:Class ;
  rdfs:label "Classical swine fever virus E1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001012 .

obo:VO_0015516 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0003230 .

obo:VO_0000595 a rdfs:Class ;
  rdfs:label "vaccine dose" ;
  rdfs:comment "A dose of vaccine specified by the vaccine manufacturer, distributor, or a regulatory agent." ;
  rdfs:subClassOf obo:OBI_0000984 .

obo:VO_0018512 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0018505 .

obo:VO_0018650 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine Prefilled Syringe [Cervarix Grk]" ;
  rdfs:subClassOf obo:VO_0018803 .

obo:VO_0019660 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019659 , obo:VO_0020309 .

obo:VO_0005169 a rdfs:Class ;
  rdfs:label "GRAd-COV2 vaccine" ;
  rdfs:comment "A SARS-CoV 2 recombinant viral vector using Gorilla Adenovirus that encodes for SARS-CoV-2 Spike protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:NCBITaxon_33154 a rdfs:Class ;
  rdfs:label "Opisthokonta" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:VO_0001306 a rdfs:Class ;
  rdfs:label "NAGO vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is composed of neuraminidase-galactose oxidase (NAGO) a mixture of mixture of the two enzymes-neuraminidase and galactose oxidase." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0016348 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:VO_0002547 a rdfs:Class ;
  rdfs:label "aroA from Staphylococcus aureus" ;
  rdfs:comment "An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. aureus" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001405 .

obo:VO_0005118 a rdfs:Class ;
  rdfs:label "MERS England1 S1 protein subunit vaccine" ;
  rdfs:comment "A MERS DNA vaccine made of plasmid  that encoded S1 subunit only" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0004900 .

obo:VO_0011031 a rdfs:Class ;
  rdfs:label "CyaA" ;
  rdfs:comment "A study demonstrated that passive immunization with specific anti-B. pertussis adenylate cyclase antibodies or active immunization with purified B. pertussis secreted adenylate cyclase (cyaA) protect mice against a lethal respiratory challenge with B. pertussis or B. parapertussis. Results suggest that adenylate cyclase might be the primary cytotoxin responsible for mouse pulmonary lesions during respiratory tract infection with B. pertussis or with the related species B. parapertussis and is a protective antigen of B. pertussis [PubMed: 2622329]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:VO_0016013 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0003262 .

obo:VO_0018750 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0018715 .

obo:VO_0018626 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 1 UNT" ;
  rdfs:subClassOf obo:VO_0003948 .

obo:VO_0021176 a rdfs:Class ;
  rdfs:label "0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0021175 .

obo:VO_0020810 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe [PEDIARIX]" ;
  rdfs:subClassOf obo:VO_0000082 .

obo:VO_0017917 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injectable Solution [Mencevax Acwy]" ;
  rdfs:subClassOf obo:VO_0017819 .

obo:VO_0018705 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 TCID Injectable Suspension [RUDIVAX] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018704 .

obo:VO_0003750 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003749 .

obo:VO_0020922 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Live Attenuated, A-California-7-2009 (H1N1) strain Nasal Spray [Fluenz]" ;
  rdfs:subClassOf obo:VO_0004893 , obo:VO_0020921 .

obo:VO_0010728 a rdfs:Class ;
  rdfs:label "Mutacol vaccine" ;
  rdfs:comment "A live attenuated V. cholerae vaccine that is manufactured by Berna Biotech, Ltd. This vaccine uses the V. Cholera strain CVD 103-HGR." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010455 .

obo:VO_0019329 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.12 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 31 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 33 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 45 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 52 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 58 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.06 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0010175 .

obo:VO_0000425 a rdfs:Class ;
  rdfs:label "Staphylococcus toxoid vaccine" ;
  rdfs:comment "a Staphyloccoccus vaccine that is made using engineered toxoid." ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000770 .

obo:VO_0004740 a rdfs:Class ;
  rdfs:label "ALVAC-FL- env/gag vaccine" ;
  rdfs:subClassOf obo:VO_0000843 .

obo:VO_0010794 a rdfs:Class ;
  rdfs:label "Chlamydophila pneumoniae protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0000781 a rdfs:Class ;
  rdfs:label "VRP expressing VP24 vaccine" ;
  rdfs:comment "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP24 protein." ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0002812 a rdfs:Class ;
  rdfs:label "Brucella abortus exsA mutant vaccine" ;
  rdfs:comment "Brucella DeltaexsA mutant showed decreased survival in mice compared to the survival of parental strain S2308. This demonstrated that ExsA is critical for full bacterial virulence. The B. abortus exsA deletion mutant was used as a live vaccine candidate. Challenge experiments revealed that the exsA mutant strain induced superior protective immunity in BALB/c mice compared to the protective immunity induced by strain S19 or RB51" ;
  rdfs:subClassOf obo:VO_0001134 .

obo:VO_0010940 a rdfs:Class ;
  rdfs:label "Tir" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0016711 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0016674 , obo:VO_0016687 , obo:VO_0016719 .

obo:VO_0010343 a rdfs:Class ;
  rdfs:label "ERVEBO vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000726 , obo:VO_0001220 .

obo:VO_0016958 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016957 .

obo:VO_0016979 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.08 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0017443 .

obo:VO_0019748 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2022 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020494 .

obo:VO_0003476 a rdfs:Class ;
  rdfs:label "influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010298 , obo:VO_0010415 .

obo:VO_0001910 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002345 .

obo:VO_0000845 a rdfs:Class ;
  rdfs:label "VSV vector expressing Yersinia pestis lcrV vaccine" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0007683 a rdfs:Class ;
  rdfs:label "KLH-id vaccine" ;
  rdfs:comment "A cancer vaccine made of tumor protein taken from a cancer patient's plasma (liquid part of the blood) and KLH (a protein designed to increase the immune response of the vaccine)." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0017487 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tet Aktiv]" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:VO_0004877 a rdfs:Class ;
  rdfs:label "Adenovirus Type 7 Vaccine Live Oral Product" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003176 .

obo:VO_0003836 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 2 (MEF-1)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003834 .

obo:VO_0004700 a rdfs:Class ;
  rdfs:label "rAdV-SFV-E2 vaccine" ;
  rdfs:subClassOf obo:VO_0001012 .

obo:VO_0002393 a rdfs:Class ;
  rdfs:label "Canine Coronavirus-Parvovirus Vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001471 , obo:VO_0004897 , obo:VO_0012180 .

obo:VO_0018395 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe [Pnu-Imune]" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0011306 a rdfs:Class ;
  rdfs:label "E1" ;
  rdfs:comment """DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain [PubMed: 19923571].

Note:  The E1 glycoprotein is part of the 6K-E1 structural protein""" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010841 .

obo:VO_0010224 a rdfs:Class ;
  rdfs:label "zoster vaccine, unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000669 .

obo:VO_0017017 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 50" ;
  rdfs:subClassOf obo:VO_0017003 , obo:VO_0017024 , obo:VO_0017495 .

obo:VO_0010094 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA24" ;
  rdfs:comment "A GRA24 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0001284 a rdfs:Class ;
  rdfs:label "obsolete immunization target role of fungal pathogen" .

obo:VO_0011335 a rdfs:Class ;
  rdfs:label "UreB" ;
  rdfs:comment "Vaccination with poliovirus vector containing the gene for the B subunit of H. pylori urease provides significant prophylactic and strong therapeutic protection against H. pylori in mice [PubMed: 15603891]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010855 .

obo:VO_0002656 a rdfs:Class ;
  rdfs:label "rfc from Salmonella Typhimurium" ;
  rdfs:comment "An rfc mutant, in combination with an asd mutation, is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0007103 a rdfs:Class ;
  rdfs:label "recombinant Vaccinia-gp100:209-217 vaccine" ;
  rdfs:comment "A recombinant vaccinia virus encoding a modified peptide of the gp100 melanoma-melanocyte antigen with potential use in cancer immunotherapy. gp100 human antigen is a wild type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas. gp100p209 is a fragment epitope of gp100 in which the threonine in position 2 is replaced with methionine; this modification may stimulate tumor infiltrating lymphocytes (TIL) more efficiently.‚Äö√†√∂‚àö¬ß" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:NCBITaxon_91061 a rdfs:Class ;
  rdfs:label "Bacilli" ;
  rdfs:subClassOf obo:NCBITaxon_1239 .

obo:VO_0004180 a rdfs:Class ;
  rdfs:label "Leishmania vaccine using recombinant L. tarentolae strain expressing A2 antigen" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0001142 .

obo:VO_0020968 a rdfs:Class ;
  rdfs:label "Influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0003521 .

obo:VO_0016873 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Pediacel] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016813 .

obo:VO_0020774 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 CELLS [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020773 .

obo:OPL_0000073 a rdfs:Class ;
  rdfs:label "oocyst stage" ;
  rdfs:comment "A parasite lifecycle stage of sporozoa consisting of a zygote enclosed by cyst wall." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0005269 a rdfs:Class ;
  rdfs:label "authorized COVID-19 subunit vaccine" ;
  rdfs:subClassOf obo:VO_0005202 , obo:VO_0005264 .

obo:VO_0011042 a rdfs:Class ;
  rdfs:label "US7" ;
  rdfs:comment "Immunization of calves with truncated gpI (US7) protein induced gpI-specific nasal IgA, IgG1, serum neutralizing antibodies and gpI-specific peripheral lymphocyte proliferation. All immunized calves were protected from clinical disease after BHV-1 challenge. Further, nine of ten immunized calves had no intranasal viral shedding [PubMed: 8147097]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010802 .

obo:VO_0001865 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0001217 , obo:VO_0002437 , obo:VO_0007748 .

obo:VO_0001072 a rdfs:Class ;
  rdfs:label "duck enteritis virus vector" ;
  rdfs:comment "a viral vaccine vector that uses a duck enteritis virus strain" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0010178 a rdfs:Class ;
  rdfs:label "influenza, high-dose, split virus, trivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0020317 a rdfs:Class ;
  rdfs:label "Fluarix 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000045 , obo:VO_0000578 , obo:VO_0010416 .

obo:VO_0017942 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group B vaccine 0.3 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017929 .

obo:VO_0000360 a rdfs:Class ;
  rdfs:label "pcDNA1.1/Amp DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002258 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4847.22)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000542 , obo:VO_0000640 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0007748 .

obo:VO_0004529 a rdfs:Class ;
  rdfs:label "Hepatitis D DNA vaccine pcDNA3p27/Ad5F35p27" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003059 .

obo:VO_0000111 a rdfs:Class ;
  rdfs:label "Tetanus and Diphtheria Toxoids Adsorbed vaccine by MA Biologic Lab" ;
  rdfs:comment "Product Name: Tetanus & Diphtheria Toxoids Adsorbed for Adult Use" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0010765 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:OPL_0000266 a rdfs:Class ;
  rdfs:label "Plasmodium microgamete" ;
  rdfs:comment "A Plasmodium gamete that is in a matured form of exflagellated microgametocyte and found in the midgut of a mosquito vector. The microgamete fertilises the macrogamete, forming the zygote." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000264 .

obo:VO_0011003 a rdfs:Class ;
  rdfs:label "YopO" ;
  rdfs:comment "Modified yopO antigens were able to partially protect immunized mice at various levels against lethal challenge with Y. pestis KIM 1001 strain [PubMed: 18291562]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0017547 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017544 .

obo:VO_0002769 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae apxIIC and apxIVA double deletion mutant vaccine" ;
  rdfs:comment "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0004802 a rdfs:Class ;
  rdfs:label "HDAd-sFsyn vaccine" ;
  rdfs:subClassOf obo:VO_0002512 .

obo:VO_0002940 a rdfs:Class ;
  rdfs:label "obsolete Yersinia pestis guaBA mutant vaccine" ;
  rdfs:comment "A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis" .

obo:VO_0004161 a rdfs:Class ;
  rdfs:label "Rotavirus VP4/VP7 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000658 .

obo:VO_0017726 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017713 , obo:VO_0017787 .

obo:VO_0020196 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA spike protein Injectable Suspension [Spikevax]" ;
  rdfs:subClassOf obo:VO_0010359 , obo:VO_0020194 .

obo:VO_0019589 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019584 , obo:VO_0020491 .

obo:VO_0015195 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015191 , obo:VO_0015278 .

obo:VO_0001177 a rdfs:Class ;
  rdfs:label "Livacox vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001137 .

obo:VO_0004009 a rdfs:Class ;
  rdfs:label "Neospora caninum NcPDI protein vaccine" ;
  rdfs:subClassOf obo:VO_0001065 .

obo:VO_0021113 a rdfs:Class ;
  rdfs:label "influenza A virus A/Delaware/39/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Nebraska/14/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017516 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 20" ;
  rdfs:subClassOf obo:VO_0017506 .

obo:VO_0007664 a rdfs:Class ;
  rdfs:label "GM-K562 cell vaccine" ;
  rdfs:comment "A cancer vaccine comprised of K562 cells transfected with the granulocyte macrophage-colony stimulating factor (GM-CSF) gene with potential immunopotentiating properties. This vaccine may stimulate the host immune system to produce an antitumoral T-lymphocyte response, thereby inhibiting tumor growth. A cultured cell line is genetically changed to secrete GM-CSF mixed with irradiated leukemia cells obtained from a patient. Vaccines made from gene-modified cancer cells may help the body build an effective immune response to kill cancer cells. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving vaccine therapy together with imatinib mesylate may be an effective treatment for chronic myelogenous leukemia. The vaccine can also be combined with stem cell transplantation. The vaccine may induce an immune response to common myeloid antigens (e.g., Wilms' tumor-1 [WT-1], survivin, or proteinase-3) in patients with Myelodysplastic Syndrome. " ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 , obo:VO_0007658 .

obo:NCBITaxon_33550 a rdfs:Class ;
  rdfs:label "Hystricomorpha" ;
  rdfs:subClassOf obo:NCBITaxon_9989 .

obo:VO_0011341 a rdfs:Class ;
  rdfs:label "VacA" ;
  rdfs:comment "Treatment of the Helicobacter pylori vacuolating cytotoxin with very low concentrations of formaldehyde resulted in abrogation of toxic activity in both a HeLa cell vacuolation assay and an in vivo assay of gastric epithelial damage. Detoxification had only a minimal effect on the integrity of the oligomeric or monomeric structure. The toxoid retained the ability to bind to target cells and to induce high-titer neutralizing antibodies after immunization of rabbits. Furthermore, oral immunization of mice with the toxoid resulted in protection against infective challenge with mouse-adapted strains of H. pylori [PubMed: 9353041]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010855 .

obo:VO_0001656 a rdfs:Class ;
  rdfs:label "Bursal Disease Standard & Variant, Live Virus Vaccine (USDA: 12B1.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0011398 a rdfs:Class ;
  rdfs:label "IHNV DNA vaccine pIHNw-G" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012165 .

obo:VO_0004048 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus CNA Protein vaccine" ;
  rdfs:subClassOf obo:VO_0002502 .

obo:VO_0019206 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0019706 .

obo:VO_0002210 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002412 , obo:VO_0007748 .

obo:VO_0020458 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 50 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020443 .

obo:VO_0010245 a rdfs:Class ;
  rdfs:label "assay sample source variable" ;
  rdfs:comment "A variable representing the tissue or source of sample used for an assay." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0017081 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0017074 , obo:VO_0017125 , obo:VO_0017560 .

obo:VO_0002913 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium trxA mutant vaccine" ;
  rdfs:comment "A trxA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0017428 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / meningococcal group C polysaccharide Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0017672 , obo:VO_0020836 .

obo:VO_0017055 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] Box of 50" ;
  rdfs:subClassOf obo:VO_0017050 , obo:VO_0017060 , obo:VO_0017525 .

obo:NCBITaxon_314145 a rdfs:Class ;
  rdfs:label "Laurasiatheria" ;
  rdfs:subClassOf obo:NCBITaxon_1437010 .

obo:VO_0021022 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2000 PFU Injection [Varilrix]" ;
  rdfs:subClassOf obo:VO_0021020 , obo:VO_0021021 .

obo:VO_0002473 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome-Parvovirus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0001456 , obo:VO_0001511 .

obo:VO_0010364 a rdfs:Class ;
  rdfs:label "Varivax (Refrigerator) vaccine" ;
  rdfs:subClassOf obo:VO_0000119 .

obo:VO_0017249 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Suspension [Tetravac]" ;
  rdfs:subClassOf obo:VO_0017246 .

obo:VO_0018516 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018524 .

obo:VO_0004770 a rdfs:Class ;
  rdfs:label "rORFV-PRV-gC/gD vaccine" ;
  rdfs:subClassOf obo:VO_0000750 .

obo:VO_0000599 a rdfs:Class ;
  rdfs:label "recombinant vaccine vector" ;
  rdfs:comment "Vaccine vector that is a genetically engineered virus or bacterium used to deliver genetic code into the cells within the body." ;
  rdfs:subClassOf obo:VO_0000179 , obo:VO_0003674 .

obo:VO_0007335 a rdfs:Class ;
  rdfs:label "autolgous DC vaccine pulsed with autologous tumor homogenate for metastatic rcc" ;
  rdfs:comment "A cancer vaccine that uses dendritic cells pulsed with autologous tumor homogenate in combination With High Dose-IL2 and immunomodulating radiotherapy for patients with Metastatic RCC." ;
  rdfs:subClassOf obo:VO_0005494 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0019790 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0005808 a rdfs:Class ;
  rdfs:label "PfSPZ vaccine" ;
  rdfs:comment "A Live attenuated vaccine PfSPZ that immunizes against Plasmodium falciparum sporozoite." ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000455 .

obo:VO_0007363 a rdfs:Class ;
  rdfs:label "CMVpp65/gB plasmid vaccine ASP0113" ;
  rdfs:comment "A poloxamer-formulated, bivalent DNA vaccine containing two plasmids encoding both the human cytomegaloviral (CMV) tegument phosphoprotein 65 (pp65), a major internal matrix protein, and glycoprotein B (gB), an important CMV component responsible for attachment and entry into cells, with potential immunostimulatory properties. Upon intramuscular injection of CMVpp65/gB plasmid vaccine ASP0113, the expressed proteins may activate the immune system to mount both cellular and humoral immune responses against CMV-positive cells. This results in cell lysis of CMV-infected cells and prevents both viral replication and the development of CMV disease. This vaccine also provides active immunization and protective immunity against CMV infection in CMV-negative patients exposed to infected donor cells or tissues in transplant recipients. CMV infection can cause serious complications in patients receiving either allogeneic hematopoietic cell transplants (HCT) or solid organ transplants. The poloxamer-based delivery system enhances DNA delivery." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0016005 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 25" ;
  rdfs:subClassOf obo:VO_0003424 .

obo:VO_0010787 a rdfs:Class ;
  rdfs:label "Poliovirus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:PR_000001096 a rdfs:Class ;
  rdfs:label "Toll-like receptor" ;
  rdfs:comment "A protein that has a core domain composition consisting of a signal peptide, an extracellular domain with multiple Leucine rich repeat (Pfam:PF13855) domain (LRR), a cysteine-rich region, a single-pass transmembrane domain and a C-terminal cytoplasmic tail containing a TIR domain (Pfam:PF01582)." ;
  rdfs:subClassOf obo:PR_000000001 .

obo:VO_0000518 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine encoding PA63" ;
  rdfs:comment "DNA vaccine contains the gene fragment encoding AAs 173-764 of PA." ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0018664 a rdfs:Class ;
  rdfs:label "Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML [Mumpsvax]" ;
  rdfs:subClassOf obo:VO_0000074 , obo:VO_0018663 .

obo:VO_0020763 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG Injectable Solution [OncoTICE] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0020762 .

obo:VO_0004078 a rdfs:Class ;
  rdfs:label "VRP vaccine" ;
  rdfs:subClassOf obo:VO_0012187 .

obo:VO_0016917 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0016916 , obo:VO_0017298 .

obo:NCBITaxon_2169991 a rdfs:Class ;
  rdfs:label "Mammarenavirus juninense" ;
  rdfs:subClassOf obo:NCBITaxon_1653394 .

obo:VO_0018299 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT Injection [RabAvert]" ;
  rdfs:subClassOf obo:VO_0018255 , obo:VO_0018306 .

obo:VO_0000097 a rdfs:Class ;
  rdfs:label "RotaTeq vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0000658 , obo:VO_0000714 , obo:VO_0001220 , obo:VO_0010449 .

obo:VO_0011327 a rdfs:Class ;
  rdfs:label "PLB" ;
  rdfs:comment "C57BL/6 mice immunized with rPlb showed a significant reduction of the fungal burden in their lungs at 90 days postchallenge compared to the control mice at 15 days [PubMed: 16369008]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010853 .

obo:VO_0016270 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015923 .

obo:OPL_0000103 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum merozoite stage" ;
  rdfs:comment "A merozoite stage in the Plasmodium falciparum lifecycle that occurs in the bloodstream or hepatocytes of a human host." ;
  rdfs:subClassOf obo:OPL_0000036 , obo:OPL_0000165 , obo:OPL_0000292 .

obo:VO_0002843 a rdfs:Class ;
  rdfs:label "Francisella tularensis FTT0918 mutant vaccine" ;
  rdfs:comment "An FTT0918 mutant showed significantly reduced virulence in mice. Mice that recovered from infection with the mutant were protected 2 months later from challenge with wild type F. tularensis" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0001812 a rdfs:Class ;
  rdfs:label "West Nile Virus Killed Virus Vaccine (USDA: 1995.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000752 , obo:VO_0001475 , obo:VO_0007748 .

obo:VO_0015313 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injectable Solution [Hav Sorbat Ssw]" ;
  rdfs:subClassOf obo:VO_0015312 .

obo:VO_0007721 a rdfs:Class ;
  rdfs:label "PD-L1/IDO peptide vaccine IO102-103" ;
  rdfs:comment "A cancer vaccine composed of IO103, a peptide derived from the tumor-associated antigen (TAA) programmed cell death-1 ligand 1 (PD-L1), IO102, the 21-mer peptide vaccine derived from the immunomodulatory enzyme indoleamine 2,3-dioxygenase (IDO), and the immunoadjuvant montanide ISA-51, with potential immunomodulating and antineoplastic activities. Both IDO and PD-L1 reactive CD8 T cells are cytotoxic and can kill cancer cells and immune regulatory cells in vitro. Thus boosting specific T cells that recognize immune regulatory proteins such as IDO and PD-L1 may directly modulate immune regulation. The the programmed death 1 (PD-1) regulatory antibody Nivolumab may further help treat patients with metastatic melanoma." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0001714 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.16)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0007528 a rdfs:Class ;
  rdfs:label "Mouse gp100 Plasmid DNA vaccine" ;
  rdfs:comment "A vaccine consisting of a plasmid DNA encoding the murine melanoma-associated antigen gp100. Upon administration, expressed gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune response against tumor cells that express the gp100 antigen, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0010919 a rdfs:Class ;
  rdfs:label "EsxA" ;
  rdfs:comment "The heterologous prime-boost strategy of live Salmonella vaccine expressing Mycobacterium tuberculosis fusion antigen Age5B-ESAT6 (esxA) from the chromosome followed by a systemic boost of antigen and adjuvant reduced the levels of M. tuberculosis bacteria in the lungs and spleen to the same extent as BCG. Additionally, this vaccination regimen was observed to be statistically equivalent in terms of protection to immunisation with BCG [PubMed: 19755145]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:DOID_18 a rdfs:Class ;
  rdfs:label "urinary system disease"@en ;
  rdfs:comment "A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra."@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:VO_0002697 a rdfs:Class ;
  rdfs:label "phoP from Yersinia pseudotuberculosis" ;
  rdfs:comment "A phoP mutant in Yersinia pseudotuberculosis (Yptb) was attenuated and provided protection against oral challenge with virulent Yptb in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001427 .

obo:VO_0000576 a rdfs:Class ;
  rdfs:label "thimerosal vaccine preservative" ;
  rdfs:comment "vaccine preservative that has thimerosal as part." ;
  rdfs:subClassOf obo:VO_0000851 .

obo:VO_0005094 a rdfs:Class ;
  rdfs:label "RBD-HBsAg VLP vaccine" ;
  rdfs:comment "A SARS-CoV-2 virus-like particle vaccine that contains the Receptor Binding Domain (RBD) of the SARS-CoV-2 spike (S) protein and is adjuvanted with aluminum." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005205 .

obo:VO_0006103 a rdfs:Class ;
  rdfs:label "A-910823 vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant that is squalene-based adjuvant, induces T follicular helper cells and humoral immune responses via alpha-tocopherol component." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0015703 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 3" ;
  rdfs:subClassOf obo:VO_0015569 , obo:VO_0015792 .

obo:VO_0003847 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML [Ipol]" ;
  rdfs:subClassOf obo:VO_0000054 .

obo:VO_0016616 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0016559 .

obo:OPL_0000143 a rdfs:Class ;
  rdfs:label "microgametocyte stage" ;
  rdfs:comment "A gametocyte stage where a cell differentiates into a male sexual form called microgametocyte." ;
  rdfs:subClassOf obo:OPL_0000150 .

obo:VO_0002141 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis-Marek's Disease Serotype 3, Live Marek's Disease Vector Vaccine (USDA: 16J1.R1)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002441 , obo:VO_0007748 .

obo:VO_0012406 a rdfs:Class ;
  rdfs:label "OmpP1" ;
  rdfs:comment "When chinchillas were immunized with recombinant P1 (rP1) obtained from one of these isolates (BCH-3), all animals developed antibodies specific for rP1. Immunized animals were protected against disease when challenged with BCH-3, but not with an ompP1 mutant of BCH-3 or a strain (BCH-2) possessing a heterologous P1 (91% identity). We conclude that (i) while P1 induces protection against NTHI-mediated otitis media, development of a polyvalent vaccine reflecting the variability of P1 would be necessary to construct an efficacious vaccine [PubMed: 10899849]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:PR_000001153 a rdfs:Class ;
  rdfs:label "Toll-like receptor 2" ;
  rdfs:comment "A Toll-like receptor that is a translation product of the human TLR2 gene or a 1:1 ortholog thereof." ;
  rdfs:subClassOf obo:PR_000001096 .

obo:VO_0002946 a rdfs:Class ;
  rdfs:label "Yersinia pestis yopH mutant vaccine" ;
  rdfs:comment "A yopH mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0000278 a rdfs:Class ;
  rdfs:label "vaccine function" ;
  rdfs:comment "To induce or modify protective or therapeutic immune response against a disease." ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:NCBITaxon_3052729 a rdfs:Class ;
  rdfs:label "Respirovirus bovis" ;
  rdfs:subClassOf obo:NCBITaxon_186938 .

obo:VO_0019320 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Afluria 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020299 .

obo:VO_0000815 a rdfs:Class ;
  rdfs:label "monthly" ;
  rdfs:subClassOf obo:PATO_0000044 .

obo:VO_0001831 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.29)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0002477 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0018209 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 12500 UNT / Rubella virus vaccine 1000 UNT [M.M.R. VaxPro]" ;
  rdfs:subClassOf obo:VO_0018246 .

obo:VO_0001876 a rdfs:Class ;
  rdfs:label "Bovine Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1161.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002330 .

obo:VO_0012400 a rdfs:Class ;
  rdfs:label "TmpB" ;
  rdfs:comment "Treponema pallidum-susceptible guinea pigs of strain C4D were immunized with recombinant T. pallidum antigen TmpB. Guinea pigs receiving TmpB antigen demonstrated protection expressed by the development of significantly (P less than 0.01) smaller, atypical lesions of significantly (P less than 0.01) shorter duration and devoid of or containing fewer T. pallidum organisms than lesions in the remaining immunized and control animals [PubMed: 1937794]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012358 .

obo:VO_0021118 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:OBI_0000685 a rdfs:Class ;
  rdfs:label "creating a mixture of molecules in solution" ;
  rdfs:comment "is a process with the objective to prepare a liquid solution of one or more chemicals at desired concentrations."@en ;
  rdfs:subClassOf obo:OBI_0000652 .

obo:VO_0005171 a rdfs:Class ;
  rdfs:label "KBP-COVID-19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine that is made of a protein subunit made of the RBD domain of the S protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0020957 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0018251 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0019663 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2020 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020490 .

obo:NCBITaxon_1653394 a rdfs:Class ;
  rdfs:label "Mammarenavirus" ;
  rdfs:subClassOf obo:NCBITaxon_1980410 .

obo:VO_0010850 a rdfs:Class ;
  rdfs:label "SARS-CoV protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0003822 a rdfs:Class ;
  rdfs:label "influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010318 , obo:VO_0010415 .

obo:VO_0004104 a rdfs:Class ;
  rdfs:label "VEE virus complex-specific monoclonal antibody vaccine" ;
  rdfs:subClassOf obo:VO_0001499 .

obo:VO_0010805 a rdfs:Class ;
  rdfs:label "Newcastle disease virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:NCBITaxon_10245 a rdfs:Class ;
  rdfs:label "Vaccinia virus" ;
  rdfs:subClassOf obo:NCBITaxon_10242 .

obo:VO_0017141 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017129 , obo:VO_0017603 .

obo:VO_0019544 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0001368 a rdfs:Class ;
  rdfs:label "irradiation-inactivated vaccine" ;
  rdfs:comment "an inactivation vaccine that is prepared by irradiation inactivation." ;
  rdfs:subClassOf obo:VO_0000315 .

obo:VO_0019808 a rdfs:Class ;
  rdfs:label "influenza A virus A/Idaho/07/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Indiana/08/2018 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0000176 a rdfs:Class ;
  rdfs:label "vaccine-induced T cell differentiation" ;
  rdfs:subClassOf obo:VO_0000115 .

obo:VO_0004739 a rdfs:Class ;
  rdfs:label "ALVAC-P53 Vaccine" ;
  rdfs:comment "Several canarypox virus recombinants expressing human or murine p53 in wild-type or mutant form were constructed" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0018330 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0018318 .

obo:VO_0018042 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003836 .

obo:VO_0011495 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni FlaC protein vaccine" ;
  rdfs:subClassOf obo:VO_0012182 .

obo:OBI_0200166 a rdfs:Class ;
  rdfs:label "data transformation objective"@en ;
  rdfs:comment "An objective specification to transformation input data into output data"@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:CHEBI_2877 a rdfs:Class ;
  rdfs:label "aspartame" ;
  rdfs:comment "A dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener." ;
  rdfs:subClassOf obo:CHEBI_16670 .

obo:VO_0020979 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, Inactivated, Strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain A / South Australia / 55/2014 Type Wild 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0020978 .

obo:VO_0011302 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/equine/Kentucky/1/1981(H3N8))" ;
  rdfs:comment "Skin and mucosal vaccination of ponies with HA from influenza virus A/equine/Ky/1/81 provided complete protection from clinical signs of infection after challenge, while skin vaccination provided partial protection; DNA vaccination provided partial protection from viral shedding [PubMed: 10403592]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0001968 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1187.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0001407 a rdfs:Class ;
  rdfs:label "Bordetella bronchiseptica gene" ;
  rdfs:comment "A bacterial gene that is from Bordetella bronchiseptica." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0020789 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 500000000 CFU [Oncotice Bcg]" ;
  rdfs:subClassOf obo:VO_0020788 .

obo:VO_0001801 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome Reproductive Form, Killed Virus Vaccine (USDA: 19S5.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001511 , obo:VO_0007748 .

obo:VO_0017351 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Di Te Tuss Asid]" ;
  rdfs:subClassOf obo:VO_0017349 .

obo:VO_0007261 a rdfs:Class ;
  rdfs:label "Anti-GnRH Vaccine PEP223" ;
  rdfs:comment "A peptide vaccine derived from the synthetic peptide pyroEHWSYGLRPG, corresponding to amino acids 22-31 of mouse gonadotropin releasing hormone (GnRH), with potential immunocastration activity. PEP223 is dimerized and contains a D-lysine (k) substitution at position 6 (pyroEHWSYkLRPG) to increase its immunogenicity. Anti-GnRH vaccine PEP223 may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against GnRH, neutralizing its activity. In turn, testosterone production and tumor cell growth may be inhibited in testosterone-sensitive tumors." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0001569 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001501 .

obo:VO_0017886 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.05 MG" ;
  rdfs:subClassOf obo:VO_0015070 .

obo:VO_0002361 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Haemophilus Somnus Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0002358 , obo:VO_0003535 .

obo:VO_0000611 a rdfs:Class ;
  rdfs:label "Haemophilus parasuis vaccine" ;
  rdfs:comment "bacterial vaccine that is used to protect against Haemophilus parasuis infection" ;
  rdfs:subClassOf obo:VO_0000661 .

obo:VO_0011453 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum MOMP protein vaccine" ;
  rdfs:subClassOf obo:VO_0012176 .

obo:VO_0004931 a rdfs:Class ;
  rdfs:label "human adolescence age range at vaccination" ;
  rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ;
  rdfs:subClassOf obo:VO_0004927 .

obo:VO_0000229 a rdfs:Class ;
  rdfs:label "bacterial vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a bacterial vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0020365 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Oral Capsule [Vivotif]" ;
  rdfs:subClassOf obo:VO_0003353 , obo:VO_0020372 .

obo:VO_0002634 a rdfs:Class ;
  rdfs:label "guaA from Salmonella Enteritidis" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective in mice and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001422 .

obo:VO_0016498 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Mtk" ;
  rdfs:subClassOf obo:VO_0015979 .

obo:VO_0010139 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, tris-sucrose, 3 mcg/0.3 mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0016412 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015956 , obo:VO_0015962 .

obo:VO_0020911 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0019697 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:UBERON_0000945 a rdfs:Class ;
  rdfs:label "stomach" ;
  rdfs:comment "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." ;
  rdfs:subClassOf obo:UBERON_0004921 , obo:UBERON_0013765 .

obo:VO_0019307 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Fluzone 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019301 , obo:VO_0020480 .

obo:VO_0010375 a rdfs:Class ;
  rdfs:label "M-M-R II vaccine - patient" ;
  rdfs:comment "Patient information for M-M-R II vaccine" ;
  rdfs:subClassOf obo:VO_0000069 .

obo:VO_0010072 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi PAR3" ;
  rdfs:comment "A PAR3 protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0004095 a rdfs:Class ;
  rdfs:label "IMV-EEV vaccine" ;
  rdfs:subClassOf obo:VO_0000651 .

obo:VO_0019491 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0010437 , obo:VO_0020832 .

obo:VO_0020831 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae 0.01 MG Injection" ;
  rdfs:subClassOf obo:VO_0010437 , obo:VO_0020832 .

obo:VO_0003053 a rdfs:Class ;
  rdfs:label "intravesical route" ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0002193 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine (USDA: 19H1.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002475 , obo:VO_0007748 .

obo:VO_0011410 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis DNA vaccine encoding Ag85B protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:VO_0001763 a rdfs:Class ;
  rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0000712 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0017439 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.02 MG/ML Injection [Hiberix]" ;
  rdfs:subClassOf obo:VO_0017436 , obo:VO_0017438 .

obo:VO_0015938 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015637 , obo:VO_0016035 .

obo:NCBITaxon_423054 a rdfs:Class ;
  rdfs:label "Eimeriorina" ;
  rdfs:subClassOf obo:NCBITaxon_5794 .

obo:DOID_331 a rdfs:Class ;
  rdfs:label "central nervous system disease"@en ;
  rdfs:comment "A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system."@en ;
  rdfs:subClassOf obo:DOID_863 .

obo:VO_0011381 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 DNA vaccine AdCMVgD" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000987 .

obo:VO_0016861 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0016818 .

obo:VO_0017709 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension [Infanrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0017708 , obo:VO_0017712 , obo:VO_0017758 .

obo:VO_0021040 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0007239 a rdfs:Class ;
  rdfs:label "Alpha-type-1 polarized dendritic cell vaccine" ;
  rdfs:comment "A mature polarized dendritic cell with potent immunostimulating activity. Treating dendritic cells (DCs) with interferon-alpha (IFN-a) and polyinosinic:polycytidylic acid (p-I:C) in addition to a cytokine cocktail (tumor necrosis factor alpha/Interleukin-1beta/IFN-gamma) produces mature but not exhausted alpha type-1 polarized DCs (alphaDC1) that are capable of: 1) high responsiveness to other lymphoid chemokines, and 2) producing high level of interleukin-12p70 (IL-12p70). Therefore, alphaDC1 has a much more significant capability of inducing helper T cell (CD4+ T-cell) responses in comparison with the \"\"gold standard\"\" DCs. When pulsed with specific tumor associated antigens (TAAs), alphaDC1 is able to induce a potent cytotoxic T lymphocyte (CTL) response against TAAs; as a result it can be used as a cancer vaccine." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0020697 a rdfs:Class ;
  rdfs:label "Antigens Surface Of Virus Influenza, strain B / Brisbane / 9/2014 Wild Type 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0020696 .

obo:VO_0001771 a rdfs:Class ;
  rdfs:label "equine influenza killed virus vaccine (USDA: 1505.21)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0001176 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0004494 a rdfs:Class ;
  rdfs:label "VHSV DNA vaccine pVHS-G encoding glycoproteins" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001224 .

obo:VO_0004285 a rdfs:Class ;
  rdfs:label "recombinant Brucella abortus CobB protein vaccine with CFA/IFA adjuvant" ;
  rdfs:subClassOf obo:VO_0000108 , obo:VO_0000484 .

obo:VO_0002130 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.24)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002421 , obo:VO_0007748 .

obo:VO_0000211 a rdfs:Class ;
  rdfs:label "vaccine organism inactivated" ;
  rdfs:comment "an organismal quality of a whole organism vaccine where the whole organism is inactivated/killed and lacks the capability of replication. " ;
  rdfs:subClassOf obo:VO_0001139 .

obo:VO_0010732 a rdfs:Class ;
  rdfs:label "obsolete Pneumovax 23 (Canada)" ;
  rdfs:comment "Trade Name: Pneumovax 23" .

obo:VO_0007073 a rdfs:Class ;
  rdfs:label "p.DOM-WT1-37 DNA Vaccine" ;
  rdfs:comment "A fusion DNA vaccine containing the first domain of fragment C (FrC) of tetanus toxin (TT865-1120) (p.DOM) fused to the human Wilms' Tumor gene-1 (WT1)-derived MHC class I-binding epitope WT1.37, with potential antitumor activity. Upon vaccination with p.DOM-WT1-37 DNA and subsequent electroporation, this vaccine may induce a WT1 epitope-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing cancer cells. WT1, a tumor associated antigen, is overexpressed in most types of leukemia and in a variety of solid cancers. The FrC of tetanus toxin contains the MHC II-binding sequence, p30, which induces T-helper cell activation for long-lasting immunity." ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 , obo:VO_0007660 .

obo:CHEBI_30911 a rdfs:Class ;
  rdfs:label "glucitol" ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0017476 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017475 .

obo:VO_0004359 a rdfs:Class ;
  rdfs:label "Hepatitis B DNA vaccine pCEA/HBsAg encoding CEA and HBsAg" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000644 .

obo:VO_0004000 a rdfs:Class ;
  rdfs:label "Brucella melitensis bp26 mutant vaccine" ;
  rdfs:subClassOf obo:VO_0000709 .

obo:VO_0020752 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0020749 .

obo:VO_0006028 a rdfs:Class ;
  rdfs:label "leprosy vaccine" ;
  rdfs:comment "Mycobacterium vaccine that is used to protect against leprosy infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000592 .

obo:VO_0003543 a rdfs:Class ;
  rdfs:label "Morbillivirus vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Morbillivirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0010199 a rdfs:Class ;
  rdfs:label "Japanese Encephalitis vaccine SC" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010440 .

obo:VO_0010256 a rdfs:Class ;
  rdfs:label "vaccine antigen variable" ;
  rdfs:comment "A variable representing the vaccine antigen (SARS-CoV-2 protein, whole organism) etc." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0017189 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017188 , obo:VO_0017632 .

obo:VO_0021146 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.04 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 .

obo:VO_0003498 a rdfs:Class ;
  rdfs:label "human influenza A (H1N1) virus vaccine" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003495 .

obo:VO_0016191 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Gerke" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:VO_0018653 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018797 .

obo:VO_0002402 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002403 .

obo:VO_0003858 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003857 .

obo:VO_0007686 a rdfs:Class ;
  rdfs:label "LMP2A-loaded conventional DC vaccine" ;
  rdfs:comment "A cancer vaccine made with Epstein Barr Virus (EBV)-derived tumor antigen, Latent Membrane Protein-2 (LMP2)-loaded dendritic cell (DC) vaccines are administered alone or co-administered with the TLR9 ligand, DUK-CPG-001, in patients with EBV+ lymphoma in the setting of autologous stem cell transplant with infusion of mature T cells. It may induce EBV derived tumor antigen specific CD8+ T cell response in patients with EBV+ lymphoma in the setting of autologous stem cell transplant." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0007125 a rdfs:Class ;
  rdfs:label "Survivin Sur1M2 Peptide Vaccine" ;
  rdfs:comment "A modified recombinant nonapeptide (LMLGEFLKL) derived from the anti-apoptosis protein survivin with potential immunopotentiating and antineoplastic activities. Upon administration, survivin Sur1M2 peptide vaccine may elicit humoral and cellular immune responses against survivin-expressing cancers, resulting in decreased tumor cell proliferation and tumor cell death. The survivin protein inhibits caspase activation and apoptosis; it is undetectable in normal adult tissues but is expressed by several human cancers including lung, colon, breast, pancreas, and prostate cancer as well as hematopoietic malignancies and skin cancers." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0019732 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/11/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Delaware/55/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML / influenza B virus B/Singapore/WUH4618/2021 antigen 0.03 MG/ML Injectable Suspension [Flucelvax Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020335 .

obo:VO_0010791 a rdfs:Class ;
  rdfs:label "Yellow fever virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0020335 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2022-2023 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003070 , obo:VO_0010428 .

obo:VO_0011421 a rdfs:Class ;
  rdfs:label "Herpes simplex virus type 1 DNA vaccine encoding GD" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000958 .

obo:NCBITaxon_224914 a rdfs:Class ;
  rdfs:label "Brucella melitensis bv. 1 str. 16M" ;
  rdfs:subClassOf obo:NCBITaxon_29459 .

obo:VO_0002494 a rdfs:Class ;
  rdfs:label "influenza vaccine (whole virion, inactivated)" ;
  rdfs:comment """created according to 
WHO Technical Report Series, No. 927, 2005
Annex 3
Recommendations for the production and control of influenza vaccine (inactivated)""" ;
  rdfs:subClassOf obo:VO_0001176 .

obo:VO_0005099 a rdfs:Class ;
  rdfs:label "VLA2001 vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated, Vero-cell based vaccine adjuvanted with aluminum and CpG 1018. It uses the manufacturing platform of Valneva's commercial Japanese encephalitis (JE) vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0001262 a rdfs:Class ;
  rdfs:label "cationic liposomal vaccine adjuvant DDA:TDB" ;
  rdfs:comment "A liposome-based vaccine adjuvant that have a positive surface charge." ;
  rdfs:subClassOf obo:VO_0000366 .

obo:VO_0017909 a rdfs:Class ;
  rdfs:label "Haemophilus B Conjugate Vaccine / meningococcal group C polysaccharide Injectable Solution [Menitorix]" ;
  rdfs:subClassOf obo:VO_0017934 .

obo:NCBITaxon_691956 a rdfs:Class ;
  rdfs:label "Avihepatovirus A" ;
  rdfs:subClassOf obo:NCBITaxon_12058 .

obo:VO_0016928 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML / tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016927 .

obo:VO_0015855 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] by MSD" ;
  rdfs:subClassOf obo:VO_0015648 .

obo:VO_0020617 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0020616 , obo:VO_0021036 .

obo:VO_0017939 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injection [Meningitec]" ;
  rdfs:subClassOf obo:VO_0017906 .

obo:VO_0017650 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [Tetatoxoid]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0018323 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0018295 , obo:VO_0018310 .

obo:OBI_0003456 a rdfs:Class ;
  rdfs:label "in vivo challenge" ;
  rdfs:comment "The administration of a challenge to a live host."@en ;
  rdfs:subClassOf obo:OBI_0600007 .

obo:OPL_0000170 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum microgamete stage" ;
  rdfs:comment "A microgamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000026 , obo:OPL_0000262 , obo:OPL_0000288 .

obo:NCBITaxon_2560602 a rdfs:Class ;
  rdfs:label "Mumps orthorubulavirus" ;
  rdfs:subClassOf obo:NCBITaxon_2560080 .

obo:VO_0004089 a rdfs:Class ;
  rdfs:label "ACAM1000 vaccine" ;
  rdfs:comment "Earlier investigational version of a smallpox vaccine developed by Acambis. It was part of the development process that led to the creation of ACAM2000. " ;
  rdfs:subClassOf obo:VO_0000651 .

obo:VO_0005247 a rdfs:Class ;
  rdfs:label "V-01 vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine developed by Livzon Mabpharm Inc." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0001188 a rdfs:Class ;
  rdfs:label "vaccine strain datum" ;
  rdfs:comment "A measurement datum that represents a vaccine strain. Different strains can be represented using distinct digital numbers. " ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0015035 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 16 Vaccine 0.12 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 31 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 33 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 45 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 52 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 58 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 6 Vaccine 0.06 MG/ML [Gardasil 9]" ;
  rdfs:subClassOf obo:VO_0003075 .

obo:VO_0002188 a rdfs:Class ;
  rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.22)" .

obo:VO_0004809 a rdfs:Class ;
  rdfs:label "2008-2009 trivalent influenza vaccine" ;
  rdfs:comment "A/Brisbane/59/2007(H1N1), A/Brisbane/10/2007(H3N2), B/Florida/4/2006; Sanofi-Pasteur" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001236 , obo:VO_0010415 .

obo:DOID_162 a rdfs:Class ;
  rdfs:label "cancer"@en ;
  rdfs:comment "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis."@en ;
  rdfs:subClassOf obo:DOID_14566 .

obo:VO_0018165 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML [Priorix]" ;
  rdfs:subClassOf obo:VO_0018164 .

obo:VO_0016055 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 250" ;
  rdfs:subClassOf obo:VO_0003259 .

obo:VO_0016505 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Mevita" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:VO_0021107 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020327 .

obo:VO_0007546 a rdfs:Class ;
  rdfs:label "LMP-2:340-349 Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine containing amino acids residues from 340 through 349 of the latent membrane protein-2 (LMP-2) of the Epstein-Barr virus (EBV) with potential immunostimulating and antineoplastic activities. LMP-2, an EBV transmembrane protein, is expressed in various malignancies including nasopharyngeal cancer and EBV-positive Hodgkin's disease. Vaccination with the LMP-2:340-349 peptide may boost the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against LMP-2 producing cells, resulting in cell lysis and inhibition of cancer cell proliferation" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005498 , obo:VO_0007657 .

obo:VO_0002806 a rdfs:Class ;
  rdfs:label "obsolete Bordetella bronchiseptica aroA/trpE mutant vaccine" ;
  rdfs:comment "A trpE mutant, in combination with an aroA mutation, is attenuated in mice and induces significant protection from challenge with wild type B. bronchiseptica" .

obo:VO_0011020 a rdfs:Class ;
  rdfs:label "ApxIIA" ;
  rdfs:comment "The levels of local and systemic antibodies specific to the Apx antigens were investigated in mice orally immunized with Apx antigen-expressing yeast.  Specific IgA responses to ApxIA or ApxIIA in the intestines and lungs from mice immunized with yeast expressing Apx antigens were significantly higher than those in the control groups after the second and third immunizations, respectively (p < 0.05).  All mice were monitored for up to 72 h after challenge with the MLD of an A. pleuropneumoniae field isolate. Overall, the final survival rates of the vaccinated groups were higher than those of the control groups at each time point [PubMed: 17993753]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010821 .

obo:VO_0002984 a rdfs:Class ;
  rdfs:label "obsolete Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine" ;
  rdfs:comment "A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" .

obo:VO_0018530 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension [Ixiaro] Box of 1" ;
  rdfs:subClassOf obo:VO_0018529 , obo:VO_0018533 , obo:VO_0018622 .

obo:VO_0011118 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/duck/Badung-Bali/05/2005(H5N1))" ;
  rdfs:comment "Mice vaccinated with a recombinant VLP vaccine from both influenza A H5N1 clade 1 and clade 2 isolates (Influenza A virus (A/duck/Badung-Bali/05/2005(H5N1))) with pandemic potential were protected against challenge with lethal reassortant viruses expressing the H5N1 HA and NA, regardless if the H5N1 clade was homologous or heterologous to the vaccine [PubMed: 18231588]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0020421 a rdfs:Class ;
  rdfs:label "typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1" ;
  rdfs:subClassOf obo:VO_0020392 , obo:VO_0020426 .

obo:VO_0000010 a rdfs:Class ;
  rdfs:label "vaccine-induced B cell cytokine production" ;
  rdfs:subClassOf obo:VO_0000012 .

obo:VO_0003117 a rdfs:Class ;
  rdfs:label "Virivac vaccine" ;
  rdfs:comment "A combined live virus vaccine used to prevent measles, mumps, and rubella." ;
  rdfs:subClassOf obo:VO_0000641 , obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0010956 a rdfs:Class ;
  rdfs:label "CjaA from C. jejuni" ;
  rdfs:comment "A total of 840 Light Sussex chickens were used to evaluate a Salmonella enterica serovar Typhimurium DeltaaroA vaccine  expressing the C. jejuni amino acid binding protein CjaA.  Chickens were given the vaccine at 1-day-old and two weeks later by oral gavage, then challenged after a further two weeks with C. jejuni. Across six biological replicates, statistically significant reductions in caecal C. jejuni of c. 1.4log(10) colony-forming units/g were observed at three and four weeks post-challenge relative to age-matched unvaccinated birds. Protection was associated with the induction of CjaA-specific serum IgY and biliary IgA [PubMed: 19853682]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010765 .

obo:VO_0018893 a rdfs:Class ;
  rdfs:label "influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0018765 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018761 .

obo:BFO_0000009 a rdfs:Class ;
  rdfs:label "two-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:VO_0000417 a rdfs:Class ;
  rdfs:label "protozoan vaccine" ;
  rdfs:comment "A vaccine that protects against some protozoan disease." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005563 .

obo:VO_0005338 a rdfs:Class ;
  rdfs:label "SCTV01C vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine by Sinocelltech Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0018154 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 50" ;
  rdfs:subClassOf obo:VO_0018150 , obo:VO_0018160 .

obo:VO_0017340 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Pediacel]" ;
  rdfs:subClassOf obo:VO_0017339 .

obo:VO_0003357 a rdfs:Class ;
  rdfs:label "Vivotif Oral Product" ;
  rdfs:subClassOf obo:VO_0003353 .

obo:VO_0011493 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni MBP-FlaA protein vaccine" ;
  rdfs:subClassOf obo:VO_0012182 .

obo:VO_0018216 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT / Varicella Virus Vaccine Live (Oka-Merck) strain 1000 UNT [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0010735 , obo:VO_0018248 .

obo:VO_0000498 a rdfs:Class ;
  rdfs:label "modification of adaptive immune response to antigen" ;
  rdfs:comment "modification of adaptive immune response to antigen is an active immunization process that results in modification of an adaptive immune response to some antigens, for example, in a therapeutic vaccine." ;
  rdfs:subClassOf obo:VO_0000491 .

obo:VO_0017661 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Tetanol]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0015043 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 33 Vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003305 .

obo:VO_0002382 a rdfs:Class ;
  rdfs:label "Bursal disease-Mareks disease vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001497 , obo:VO_0012162 .

obo:VO_0018488 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018442 .

obo:VO_0017897 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine Injection" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0001094 a rdfs:Class ;
  rdfs:label "pregnant women" ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:VO_0002623 a rdfs:Class ;
  rdfs:label "obsolete clpP from Salmonella spp." ;
  rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" .

obo:VO_0011280 a rdfs:Class ;
  rdfs:label "SW3.1" ;
  rdfs:comment "In a murine model of experimental cutaneous leishmaniasis, researchers investigated the protection elicited by injection of histone H1 (SW3.1) isolated from parasites by perchloric extraction, of a H1 recombinant protein produced in E. coli, and of H1 long and short synthetic peptides, against infection by L. major. Partial protection was achieved in most of the animals as shown by reduction in lesion size, upon immunization with histone H1 or its peptides, provided that the region 1-60 was present in the molecule [PubMed: 10580198]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0020735 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017679 .

obo:VO_0004191 a rdfs:Class ;
  rdfs:label "Pseudomonas aeruginosa PcrV protein vaccine" ;
  rdfs:subClassOf obo:VO_0000393 .

obo:VO_0019197 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019675 .

obo:VO_0010906 a rdfs:Class ;
  rdfs:label "HAVgp2" ;
  rdfs:comment "A recombinant vaccinia virus containing most of the P1 region of hepatitis A virus (HAV) was constructed bearing epitopes from structural polypeptides VP4, -3 and -2, and the N terminus of VP. Inoculation of tamarin monkeys with the recombinant virus resulted in the development of a specific anti-HAV immune response which was protective against challenge with a virulent strain of HAV [PubMed: 1654376]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010780 .

obo:VO_0011561 a rdfs:Class ;
  rdfs:label "Andes virus vaccine using adenovirus viral vector expressing ANDV NP" ;
  rdfs:subClassOf obo:VO_0012167 .

obo:VO_0015892 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015622 , obo:VO_0015623 , obo:VO_0015729 , obo:VO_0015735 , obo:VO_0016009 .

obo:VO_0003662 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010313 , obo:VO_0010415 .

obo:VO_0011015 a rdfs:Class ;
  rdfs:label "YopH from Y. pestis CO92" ;
  rdfs:comment "Study evaluated the humoral immune response of mice that survived lethal Y. pestis aerosol challenge after antibiotic treatment.  Results indicated that one of the predominant antibody response of mice surviving pneumonic plague after treatment with antibiotics was to yopH [PubMed: 10085037]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0000916 a rdfs:Class ;
  rdfs:label "protamine sulfate vaccine allergen" ;
  rdfs:subClassOf obo:VO_0000910 .

obo:VO_0018384 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML [Pneumovax II]" ;
  rdfs:subClassOf obo:VO_0018400 .

obo:VO_0004547 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine expressing prM/E protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0011234 a rdfs:Class ;
  rdfs:label "OmpA" ;
  rdfs:comment "Immunization with one of the constructs of M. vaccae expressing OmpA in combination with booster immunization with the homologous recombinant protein protected a significant portion of mice from lethal challenge [PubMed: 11738766]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010846 .

obo:VO_0021037 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0021035 , obo:VO_0021039 .

obo:VO_0001498 a rdfs:Class ;
  rdfs:label "Eastern Equine Encephalitis Virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Eastern Equine Encephalitis Virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0015631 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0015565 , obo:VO_0015667 .

obo:VO_0017152 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017610 .

obo:VO_0001651 a rdfs:Class ;
  rdfs:label "Bursal Disease Modified Live VirusVaccine (USDA: 1271.15)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0004859 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide" ;
  rdfs:comment "CUI: C0065944" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0018088 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution [Priorix] Box of 20" ;
  rdfs:subClassOf obo:VO_0018085 , obo:VO_0018092 , obo:VO_0018169 .

obo:VO_0007014 a rdfs:Class ;
  rdfs:label "Recombinant dHER2 Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a truncated recombinant HER2 peptide (dHER2) with potential antineoplastic activity. Upon administration, recombinant dHER2 vaccine may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against tumor cells that overexpress the HER2 protein, resulting in tumor cell lysis. The HER2 protein is a tumor-associated antigen (TAA) that is overexpressed in a variety of cancers. dHER2 includes the extracellular domain (ECD) and a part of the intracellular domain (ICD) of the HER2 protein." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0007732 a rdfs:Class ;
  rdfs:label "secPD-L1 vaccine" ;
  rdfs:comment "A cancer vaccine made with secPD-L1, a splice variant of PD-L1 (programmed death ligand-1, an immune checkpoint pathway) that does not splice into the transmembrane domain, but instead produces a secreted form of PD-L1 that has a unique 18 amino acid tail containing a cysteine that allows it to homodimerize and more effectively inhibit lymphocyte function than monomeric soluble PD-L1. Recombinant secPD-L1 can dimerize and inhibit T-cell proliferation and IFN-gamma production in vitro. SecPD-L1 may function as a paracrine negative immune regulator within the tumor, since secPD-L1 does not require a cell-to-cell interaction to mediate its inhibitory effect. This could lead to improved survival for patients with numerous types of cancers, including lung cancer, melanoma, renal cell carcinoma, and Hodgkin lymphoma." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0015563 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax]" ;
  rdfs:subClassOf obo:VO_0015489 , obo:VO_0015548 .

obo:VO_0015823 a rdfs:Class ;
  rdfs:label "0.5 ML hepatitis B surface antigen vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] by Organon" ;
  rdfs:subClassOf obo:VO_0015615 .

obo:VO_0020070 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020478 .

obo:VO_0018103 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018237 .

obo:VO_0004331 a rdfs:Class ;
  rdfs:label "Human papillomavirus DNA vaccine CRT/E7 DNA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000667 .

obo:VO_0016371 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0016214 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Mevita" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0010219 a rdfs:Class ;
  rdfs:label "pneumococcal vaccine, unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010453 .

obo:VO_0001906 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid (USDA: 43T5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002348 .

obo:VO_0005088 a rdfs:Class ;
  rdfs:label "EpiVacCorona vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine that relies on chemically synthesized peptide antigens of SARS-CoV-2 proteins, conjugated to a carrier protein and adsorbed on an aluminum-containing adjuvant (aluminum hydroxide)." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0011555 a rdfs:Class ;
  rdfs:label "Rabies vaccine rVac-N" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0011121 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/environment/Hong Kong/156/1997(H5N1))" ;
  rdfs:comment "Researchers report that a DNA vaccine encoding hemagglutinin from the index human influenza isolate A/HK/156/97 provides immunity against H5N1 infection of mice [PubMed: 9971791]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:OPL_0000305 a rdfs:Class ;
  rdfs:label "Plasmodium erythrocytic ring trophozoite stage" ;
  rdfs:comment "An erythrocytic ring trophozoite stage in the Plasmodium life cycle that occurs in erythrocytes of a vertebrate host. During this stage some Plasmodium merozoites undergo asexual reproduction cycle in erythrocytes and form young trophozoites that are referred to as \"ring form\" due to their morphology." ;
  rdfs:subClassOf obo:OPL_0000140 , obo:OPL_0000304 .

obo:VO_0019726 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003693 , obo:VO_0010427 .

obo:VO_0000855 a rdfs:Class ;
  rdfs:label "inactivation residual in vaccine" ;
  rdfs:comment "a vaccine residual that is used to inactivate bacteria and viruses or to detoxify bacterial toxins. For example, formaldehyde is a frequently used inactivation agent in vaccine preparation." ;
  rdfs:subClassOf obo:VO_0000854 .

obo:VO_0019820 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003903 .

obo:VO_0000627 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b capsular polysaccharide vaccine" ;
  rdfs:comment "A vaccine used to prevent infection by Haemophilus influenzae type b (Hib) bacteria. The vaccine works by causing your body to produce its own protection (antibodies) against the disease." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001255 , obo:VO_0010437 .

obo:VO_0015620 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015572 , obo:VO_0015661 .

obo:VO_0005020 a rdfs:Class ;
  rdfs:label "pSecTag2B DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pSecTag2B.  This plasmid is 5163 base pairs in length and contains a CMV promoter and ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0004679 a rdfs:Class ;
  rdfs:label "RBD-rAAV-SARS-CoV prime/RBD-specific T cell peptide boost vaccine" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0011515 a rdfs:Class ;
  rdfs:label "Mycoplasma gallisepticum TM-1 protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000949 , obo:VO_0001077 .

obo:VO_0002832 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda aroC/esrC mutant vaccine" ;
  rdfs:comment "An aroC and esrC mutant is attenuated in zebra fish. This mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 71.3%" ;
  rdfs:subClassOf obo:VO_0002506 .

obo:VO_0001555 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis Modified Live Virus Vaccine (USDA: 16A1.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001220 , obo:VO_0001487 , obo:VO_0007748 .

obo:VO_0003979 a rdfs:Class ;
  rdfs:label "KINRIX vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003974 .

obo:VO_0019686 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2016 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020488 .

obo:VO_0017375 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Dt Impfstoff]" ;
  rdfs:subClassOf obo:VO_0018786 .

obo:VO_0016692 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.5 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0010181 a rdfs:Class ;
  rdfs:label "seasonal influenza, intradermal, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:NCBITaxon_286 a rdfs:Class ;
  rdfs:label "Pseudomonas" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:VO_0002989 a rdfs:Class ;
  rdfs:label "Pseudorabies virus UL50 mutant vaccine" ;
  rdfs:comment "A UL50 mutant is attenuated in pseudorabies virus and induces significant protection in pigs from challenge with the highly virulent NIA-3 strain of PrV" ;
  rdfs:subClassOf obo:VO_0000750 .

obo:VO_0003487 a rdfs:Class ;
  rdfs:label "influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010300 , obo:VO_0010415 .

obo:VO_0002413 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Vaccine" ;
  rdfs:subClassOf obo:VO_0002394 , obo:VO_0012180 .

obo:VO_0016743 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] Box of 20" ;
  rdfs:subClassOf obo:VO_0016710 , obo:VO_0016770 .

obo:BFO_0000028 a rdfs:Class ;
  rdfs:label "three-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:VO_0017171 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017620 .

obo:OPL_0000249 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum gametocyte" ;
  rdfs:comment "A Plasmodium falciparum that is located either in the bloodstream of the human host or midgut of mosquito vector. Gametocytes are the precursor cells of the macro- or micro-gametes." ;
  rdfs:subClassOf obo:NCBITaxon_5833 , obo:OPL_0000267 .

obo:VO_0001981 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:CHEBI_23367 a rdfs:Class ;
  rdfs:label "molecular entity" ;
  rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ;
  rdfs:subClassOf obo:CHEBI_24431 .

obo:VO_0017502 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017684 .

obo:VO_0018738 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 2000000000 ORGANISMS Delayed Release Oral Capsule Box of 3" ;
  rdfs:subClassOf obo:VO_0018734 .

obo:VO_0004274 a rdfs:Class ;
  rdfs:label "HIV recombinant gp160 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000295 , obo:VO_0000484 .

obo:VO_0018173 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML" ;
  rdfs:subClassOf obo:VO_0015052 .

obo:VO_0016040 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015669 , obo:VO_0015795 .

obo:VO_0007417 a rdfs:Class ;
  rdfs:label "Montanide ISA-51/survivin peptide vaccine" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0007084 a rdfs:Class ;
  rdfs:label "Recombinant Adenovirus-L523S Vaccine" ;
  rdfs:comment "A replication-defective adenovirus containing a gene that encodes the human protein L523S with potential antineoplastic activity. Upon administration, recombinant adenovirus-L523S vaccine expresses L523S, which may stimulate antibody and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing L523S. L523S is an RNA-binding protein that belongs to the KOC (K homology domain containing protein over-expressed in cancer) family of proteins. As an oncofetal protein, L523S is normally expressed in early embryonic tissues and certain normal adult tissues such as colon, fallopian tube, gall bladder, and ovary tissues but may be overexpressed in squamous cell cancers of the lung." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0007273 a rdfs:Class ;
  rdfs:label "adenovirus-transfected autologous dc vaccine plus cik cells" ;
  rdfs:comment "A cancer vaccine that uses adenovirus MUC1 and Survivin transfected autologous dendritic cells combined with cytokine-induced killer cells in cancer patients with Extensive-Stage Small- Cell Lung Cancer." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0003474 a rdfs:Class ;
  rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010303 , obo:VO_0010415 .

obo:OBI_0001930 a rdfs:Class ;
  rdfs:label "categorical value specification" ;
  rdfs:comment "A value specification that is specifies one category out of a fixed number of nominal categories"@en ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:VO_0020167 a rdfs:Class ;
  rdfs:label "pertussis vaccine 8 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017808 .

obo:VO_0003261 a rdfs:Class ;
  rdfs:label "QIV Dresden vaccine" ;
  rdfs:comment "A quadrivalent influenza vaccine against two influenza A strains and two influenza B strains." ;
  rdfs:subClassOf obo:VO_0001176 , obo:VO_0003495 .

obo:DOID_3119 a rdfs:Class ;
  rdfs:label "gastrointestinal system cancer"@en ;
  rdfs:comment "An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system."@en ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_77 .

obo:VO_0007653 a rdfs:Class ;
  rdfs:label "HPV associated cancer" ;
  rdfs:comment "A cancer that is caused by human papillomavirus (HPV) infection. HPV infection can lead to six types of cancer including anal, cervical, oropharyngeal, penile, vaginal, and vulvar cancer." ;
  rdfs:subClassOf obo:DOID_162 .

obo:RO_0004019 a rdf:Property ;
  rdfs:label "disease has basis in" ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0004023 , obo:RO_0004017 .

obo:VO_0020900 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0020887 , obo:VO_0020910 .

obo:VO_0004614 a rdfs:Class ;
  rdfs:label "mRNA-electroporated dendritic cells encoding gp100 and tyrosinase as melanoma vaccine" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020662 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] Box of 6" ;
  rdfs:subClassOf obo:VO_0020657 , obo:VO_0020706 .

obo:VO_0002013 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4367.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002373 .

obo:VO_0002077 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0020182 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 1000000 UNT/ML Oral Suspension" ;
  rdfs:subClassOf obo:VO_0004816 , obo:VO_0020187 .

obo:VO_0000875 a rdfs:Class ;
  rdfs:label "pSecTag-PA83 vaccine" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0012382 a rdfs:Class ;
  rdfs:label "eba-175" ;
  rdfs:comment "1 of 3 Monkeys vaccinated with EBA-175 was protected from challenge of parasitized erythrocytes [PubMed: 11471569]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010771 .

obo:VO_0018611 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000665 , obo:VO_0010440 .

obo:VO_0018888 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hawaii/66/2019 (H1N1) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0003862 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010448 .

obo:OPL_0000328 a rdfs:Class ;
  rdfs:label "Plasmodium vivax merozoite" ;
  rdfs:comment "A Plasmodium vivax that is found in the bloodstream of the human host and invades erythrocytes." ;
  rdfs:subClassOf obo:NCBITaxon_5855 , obo:OPL_0000270 .

obo:VO_0002592 a rdfs:Class ;
  rdfs:label "FTL0552 from Francisella tularensis" ;
  rdfs:comment "A FTL0552 mutant in Francisella tularensis was attenuated and provided partial protection in mice against challenge with a lethal dose of the virulent SchuS4 strain when compared to naive mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0020413 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0020389 , obo:VO_0020399 .

obo:VO_0015227 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015216 , obo:VO_0015310 .

obo:VO_0005258 a rdfs:Class ;
  rdfs:label "MF59-adjuvanted SARS-CoV-2 Sclamp vaccine" ;
  rdfs:comment "An MF59-adjuvanted SARS-CoV-2 subunit vaccine based on recombinant SARS-CoV-2 spike glycoprotein stabilised in a pre-fusion conformation by a novel molecular clamp (spike glycoprotein-clamp [sclamp])" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0020177 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injection [RabAvert]" ;
  rdfs:subClassOf obo:VO_0000094 , obo:VO_0018806 .

obo:VO_0002196 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1A82.50)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0007114 a rdfs:Class ;
  rdfs:label "TriMixDC-MEL Vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0004786 a rdfs:Class ;
  rdfs:label "rS.C-APP-ApxIIA vaccine" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0000635 a rdfs:Class ;
  rdfs:label "licensed human vaccine" ;
  rdfs:comment "a licensed vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000363 .

obo:VO_0000141 a rdfs:Class ;
  rdfs:label "obsolete virulence factor" .

obo:VO_0003898 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0003067 , obo:VO_0003638 .

obo:VO_0004758 a rdfs:Class ;
  rdfs:label "rMVA- AHS-VP2 vaccine" ;
  rdfs:subClassOf obo:VO_0001480 .

obo:VO_0000435 a rdfs:Class ;
  rdfs:label "DNA vaccine plasmid vector" ;
  rdfs:comment "Vaccine vector that is a DNA plasmid used to deliver the genetic code into the cells within the body. " ;
  rdfs:subClassOf obo:VO_0003674 .

obo:VO_0004536 a rdfs:Class ;
  rdfs:label "Pasteurella multocida DNA vaccine pcDNA-OMPH + pcDNA-OMPA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000620 .

obo:VO_0005472 a rdfs:Class ;
  rdfs:label "ProLNG-S vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that induces CD8 T cells and provides innate protection." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0003717 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003715 .

obo:VO_0015844 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] by Waymade" ;
  rdfs:subClassOf obo:VO_0015638 .

obo:VO_0001349 a rdfs:Class ;
  rdfs:label "SAF-1 vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant that is composed of threonyl-MDP (0.05-1%) in an emulsion vehicle [5% squalane, 2.5% Pluronic(R) L121, 0.2% Polysorbate 80 and phosphate buffered saline (pH 7.4)]." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0019541 a rdfs:Class ;
  rdfs:label "human-bovine reassortant rotavirus strain G1 vaccine / human-bovine reassortant rotavirus strain G2 vaccine / human-bovine reassortant rotavirus strain G3 vaccine / human-bovine reassortant rotavirus strain G4 vaccine / human-bovine reassortant rotavirus strain P1A[8] vaccine Oral Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010449 .

obo:VO_0000430 a rdfs:Class ;
  rdfs:label "phase 4 vaccine trial" ;
  rdfs:comment "The final stage of vaccine clinical evaluation. Phase IV occurs after a vaccine or therapy is licensed and is being used by large numbers of people. These studies are not always required or completed." ;
  rdfs:subClassOf obo:VO_0000596 .

obo:VO_0015255 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Epaxal] Box of 10" ;
  rdfs:subClassOf obo:VO_0015253 , obo:VO_0015260 .

obo:VO_0000277 a rdfs:Class ;
  rdfs:label "pK0 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001940 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0019950 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluzone 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020481 .

obo:VO_0003309 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 23F vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003252 .

obo:VO_0007176 a rdfs:Class ;
  rdfs:label "VHL-59: 116-128 Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine consisting of amino acids 116 through 128 derived from the tumor suppressor protein Von Hippel-Lindau (VHL) with a frameshift mutation. As a cancer vaccine, VHL-59: 116-128(FrSh116-128) peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0000305 a rdfs:Class ;
  rdfs:label "pRSV DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019164 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0020264 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 1000 UNT" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0001124 a rdfs:Class ;
  rdfs:label "VEE vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a Venezuelan equine encephalitis virus strain as the vaccine vector" ;
  rdfs:subClassOf obo:VO_0000144 .

obo:VO_0018877 a rdfs:Class ;
  rdfs:label "influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010301 , obo:VO_0010415 .

obo:VO_0000678 a rdfs:Class ;
  rdfs:label "Shigella sonnei virG mutant vaccine" ;
  rdfs:comment "A stable attenuated Shigella sonnei strain with virG mutation. PMID:9712824." ;
  rdfs:subClassOf obo:VO_0000679 .

obo:VO_0010818 a rdfs:Class ;
  rdfs:label "Mycoplasma synoviae protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0010472 a rdfs:Class ;
  rdfs:label "correlated profile of immune protection based on causality" ;
  rdfs:subClassOf obo:VO_0000857 .

obo:VO_0001301 a rdfs:Class ;
  rdfs:label "MF59 vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant consisting of an oil (squalene)-in-water nano emulsion." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0002128 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western & Venezuelan, Killed Virus Vaccine (USDA: 14W5.23)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002431 , obo:VO_0007748 .

obo:VO_0016646 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0018477 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 20 by Cc" ;
  rdfs:subClassOf obo:VO_0018440 , obo:VO_0018459 .

obo:VO_0004150 a rdfs:Class ;
  rdfs:label "killed vaccinia virus vaccine with adjuvant NanoEmulsion" ;
  rdfs:subClassOf obo:VO_0000651 , obo:VO_0000712 , obo:VO_0003060 .

obo:DOID_299 a rdfs:Class ;
  rdfs:label "adenocarcinoma"@en ;
  rdfs:comment "A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue."@en ;
  rdfs:subClassOf obo:DOID_305 .

obo:VO_0004826 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 1100000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0004824 .

obo:VO_0019426 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus capsular oligosaccharide Injectable Solution [Prohibit]" ;
  rdfs:subClassOf obo:VO_0000660 , obo:VO_0019425 .

obo:NCBITaxon_2611352 a rdfs:Class ;
  rdfs:label "Discoba" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:VO_0018758 a rdfs:Class ;
  rdfs:label "Vaccine, Typh.-Paratyph.A & B Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018757 .

obo:VO_0020048 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Flulaval 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020337 .

obo:VO_0015718 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015572 , obo:VO_0015797 .

obo:VO_0011150 a rdfs:Class ;
  rdfs:label "PreM" ;
  rdfs:comment "A cDNA clone representing the genome of structural proteins of Japanese encephalitis virus (JEV) was inserted into the thymidine kinase gene of vaccinia virus strains LC16mO and WR.  Inoculation of rabbits with the infectious recombinant vaccinia virus resulted in rapid production of antiserum specific for the PreM and E glycoproteins of JEV.  Mice vaccinated with the recombinant produced JEV-neutralizing antibodies and were resistant to challenge with JEV [PubMed: 2159544]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010783 .

obo:VO_0001386 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine encoding CRP-10" ;
  rdfs:comment "A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi CRP-10 protein." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0015107 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension [Havrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015106 , obo:VO_0015109 , obo:VO_0015277 .

obo:VO_0017492 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 100" ;
  rdfs:subClassOf obo:VO_0017489 , obo:VO_0017498 .

obo:NCBITaxon_9768 a rdfs:Class ;
  rdfs:label "Balaenoptera borealis" ;
  rdfs:subClassOf obo:NCBITaxon_91561 .

obo:VO_0004659 a rdfs:Class ;
  rdfs:label "VSV-DeltaG-H5 (H5N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0000602 a rdfs:Class ;
  rdfs:label "Edwardsiella vaccine" ;
  rdfs:comment "A bacterial vaccine that is used to protect against Edwardsiella bacterial infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003551 .

obo:VO_0002586 a rdfs:Class ;
  rdfs:label "carA from Escherichia coli" ;
  rdfs:comment "A carAB mutant is attenuated in turkeys and induces significant protection from challenge with wild type E. coli" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000161 .

obo:VO_0004386 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine PA" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0010985 a rdfs:Class ;
  rdfs:label "IreA" ;
  rdfs:comment "Immunization with IreA protects against urinary tract colinization by E.coli CFT073 and reduces colinization by E.coli 536 in the bladder of CBA/J mice [PubMed: 19806177]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0016867 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 5 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016823 .

obo:VO_0019519 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.0025 MG/ML Prefilled Syringe [Recombivax]" ;
  rdfs:subClassOf obo:VO_0019517 , obo:VO_0019518 .

obo:VO_0003294 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003343 .

obo:NCBITaxon_213849 a rdfs:Class ;
  rdfs:label "Campylobacterales" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:VO_0019831 a rdfs:Class ;
  rdfs:label "influenza A virus A/Norway/16606/2021 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Victoria/1/2020 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Austria/1359417/2021 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray [FluMist Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020354 .

obo:NCBITaxon_712 a rdfs:Class ;
  rdfs:label "Pasteurellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:VO_0004625 a rdfs:Class ;
  rdfs:label "rFPV-IBDV-VP2 vaccine" ;
  rdfs:subClassOf obo:VO_0001497 .

obo:VO_0007571 a rdfs:Class ;
  rdfs:label "HER2 ECD+TM virus-like replicon particles vaccine AVX901" ;
  rdfs:comment "A cancer vaccine based on virus-like replicon particles (VRP) packaged with an alphaviral vector encoding the extracellular domain (ECD) and transmembrane (TM) regions of the human epidermal growth factor receptor 2 (EGFR2, NEU or HER2), with potential antineoplastic activity. After immunization with HER2 ECD+TM virus-like replicon particles vaccine AVX901, the VRPs infect cells and express HER2 ECD+TM protein that may activate the immune system to elicit a cytotoxic T-lymphocyte (CTL) response against HER2-expressing tumor cells. The alphaviral replicon of this vaccine is an attenuated strain of the Venezuelan equine encephalitis virus (VEEV) in which 3 of the 7 viral genes were substituted with a truncated HER2 gene to create a self-amplifying replicon RNA. HER2, a tyrosine kinase involved in several cell growth signaling pathways, is dysregulated or overexpressed in a wide variety of cancer cell types." ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0007657 .

obo:VO_0005327 a rdfs:Class ;
  rdfs:label "rOv-ASP-1 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is a potent adjuvant for antibody and cellular responses to protein, polypeptide and small peptide antigens. rOv-ASP-1 stands for Recombinant Onchocerca volvulus activation-associated secreted protein-1." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0005240 a rdfs:Class ;
  rdfs:label "MV-014-212 vaccine" ;
  rdfs:comment "A SARS-CoV-2 live, attenuated vaccine manufactured by Meissa Vaccines, Inc. that expresses the spike (S) protein of SARS-CoV-2." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005204 .

obo:VO_0010772 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0015798 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 250" ;
  rdfs:subClassOf obo:VO_0015492 .

obo:VO_0019616 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flublok Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020325 .

obo:VO_0019437 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Haemophilus capsular oligosaccharide 0.02 MG/ML Injectable Suspension [HibTITER]" ;
  rdfs:subClassOf obo:VO_0000659 , obo:VO_0019436 .

obo:VO_0017388 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Repevax]" ;
  rdfs:subClassOf obo:VO_0018788 .

obo:VO_0001350 a rdfs:Class ;
  rdfs:label "Sendai Proteoliposomes, Sendai-containing Lipid Matrices" ;
  rdfs:comment "A liposome-based vaccine adjuvant that includes the glycoproteins of Sendai virus." ;
  rdfs:subClassOf obo:VO_0000366 .

obo:VO_0003806 a rdfs:Class ;
  rdfs:label "FluMist 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000044 .

obo:VO_0020006 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML Prefilled Syringe [Fluzone High-Dose 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020485 .

obo:VO_0020793 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 500000000 CFU Injection Box of 3" ;
  rdfs:subClassOf obo:VO_0020790 .

obo:VO_0005318 a rdfs:Class ;
  rdfs:label "CVXGA1 vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant vector vaccine manufactured by CyanVac LLC" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:NCBITaxon_10386 a rdfs:Class ;
  rdfs:label "Gallid alphaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_180255 .

obo:VO_0003463 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine, Inactivated 50 UNT/ML Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0003465 .

obo:VO_0002350 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002351 .

obo:VO_0017197 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017196 .

obo:VO_0011219 a rdfs:Class ;
  rdfs:label "CS from P. yoelii str. 17XNL" ;
  rdfs:comment "Study showed that immunization with irradiated sporozoites (IrrSpz) of a P. berghei line whose endogenous CS was replaced by that of P. yoelii conferred sterile protection against challenge with wild type P. berghei sporozoites [PubMed: 19890387]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015474 .

obo:VO_0020354 a rdfs:Class ;
  rdfs:label "FluMist Quadrivalent 2022-2023 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000982 , obo:VO_0010428 .

obo:VO_0010466 a rdfs:Class ;
  rdfs:label "specific correlate of immune protection" ;
  rdfs:subClassOf obo:VO_0010465 .

obo:VO_0000442 a rdfs:Class ;
  rdfs:label "CFU measurement assay" ;
  rdfs:comment "CFU measurement assay is an assay that measures the colony forming unit (CFU) of a bacterium in a specific location (e.g., spleen of a mouse)." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0016635 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by A+S Unicare" ;
  rdfs:subClassOf obo:VO_0016621 .

obo:VO_0017364 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxin Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000943 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0000241 a rdfs:Class ;
  rdfs:label "inactivated vaccine preparation using heat inactivation" ;
  rdfs:comment "A vaccine prepraration process that is performed by heat inactivation of virulent pathogen." ;
  rdfs:subClassOf obo:VO_0000178 .

obo:VO_0017201 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 20" ;
  rdfs:subClassOf obo:VO_0017188 , obo:VO_0017639 .

obo:VO_0004284 a rdfs:Class ;
  rdfs:label "African Swine Fever Virus 9GL mutant vaccine" ;
  rdfs:subClassOf obo:VO_0001211 , obo:VO_0001474 .

obo:VO_0007159 a rdfs:Class ;
  rdfs:label "pVAXrcPSAv53l DNA Vaccine" ;
  rdfs:comment "A cancer vaccine containing xenogenic DNA from rhesus macaque (Macaca mulatta) that encodes prostate specific antigen (PSA) with potential immunostimulating and antineoplastic activities. Upon repeated intradermal administration via electroporation, pVAXrcPSAv53l vaccine may induce a cytotoxic T-lymphocyte (CTL) response against PSA-expressing prostate cancer cells. Rhesus PSA is 89% homologous to human PSA." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0017751 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017741 .

obo:VO_0004205 a rdfs:Class ;
  rdfs:label "BOOSTRIX vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003995 .

obo:VO_0020446 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10" .

obo:VO_0001992 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002362 .

obo:VO_0010877 a rdfs:Class ;
  rdfs:label "Pla" ;
  rdfs:comment "Study evaluated the humoral immune response of mice that survived lethal Y. pestis aerosol challenge after antibiotic treatment. Results indicated that one of the predominant antibody response of mice surviving pneumonic plague after treatment with antibiotics was to pla [PubMed: 10085037]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0003731 a rdfs:Class ;
  rdfs:label "Afluria 2017-2018 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003728 .

obo:VO_0019383 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000743 .

obo:VO_0001500 a rdfs:Class ;
  rdfs:label "Equine arteritis virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Equine arteritis virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0020641 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0020636 , obo:VO_0021031 .

obo:VO_0019248 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019247 , obo:VO_0019775 .

obo:VO_0019375 a rdfs:Class ;
  rdfs:label "1.5 ML hepatitis B surface antigen vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0019374 .

obo:VO_0005333 a rdfs:Class ;
  rdfs:label "SII B.1.351 vaccine" ;
  rdfs:comment "A SARS-CoV-2 monovalent protein subunit vaccine by Novavax immunizing against the B.1.351 (Beta) variant and containing the Matrix-M1 adjuvant" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0004466 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine sA encoding prM and E from Dengue Virus 4" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0005072 a rdfs:Class ;
  rdfs:label "pJW4304 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pJW4304.  This plasmid is 5132 base pairs in length and contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002377 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Vaccine-Escherichia Coli Bacterin" ;
  rdfs:subClassOf obo:VO_0000041 , obo:VO_0000563 , obo:VO_0002374 .

obo:VO_0018016 a rdfs:Class ;
  rdfs:label "poliomyelitis virus type 1 brunhilde 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018012 .

obo:NCBITaxon_10509 a rdfs:Class ;
  rdfs:label "Mastadenovirus" ;
  rdfs:subClassOf obo:NCBITaxon_10508 .

obo:VO_0010895 a rdfs:Class ;
  rdfs:label "FabD" ;
  rdfs:comment "M-ID vaccination with fabD generated a response that resulted in moderately, but significantly reduced total C. pneumoniae lung loads as compared to control mice vaccinated with a plasmid expressing a non-Chlamydia ORF (p 0.019). This resulted in the ability of fabD to mediate a moderate, but statistically significant level of protection in an inbred A/J mouse respiratory challenge model [PubMed: 16434129]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010794 .

obo:VO_0005437 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, 30 mcg/0.3mL dose" ;
  rdfs:comment "A Comirnaty COVID-19 mRNA vaccine utilizing Lipid Nanoparticle-Self-amplifying RNA technology against the original strain of COVID-19 without preservative ,which is produced by Pfizer (PF) with a dose of 30 mcg/0.3 mL." ;
  rdfs:subClassOf obo:VO_0004987 .

obo:VO_0017269 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.025 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017227 .

obo:VO_0007710 a rdfs:Class ;
  rdfs:label "neoantigen synthetic long peptide vaccine" ;
  rdfs:comment "A cancer vaccine consisting of synthetic long peptides (SLPs), ranging from 20-35 amino acids in size, that are derived from two or more of the patient's tumor-specific mutant antigens (TSMAs), with potential immunostimulatory and antitumor activities. SLP vaccine may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL)-mediated immune response against the TSMAs expressed by the tumor cells. This vaccine is a optimized neoantigen synthetic long peptide (SLP) vaccines for pancreatic cancer patients following neoadjuvant chemotherapy. The neoantigen SLP vaccines will incorporate prioritized neoantigens and will be co-administered with poly-ICLC. It can be used in combination with chemoradiation with temozolomide for patients with newly diagnosed glioblastoma." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0015801 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015493 .

obo:VO_0003020 a rdfs:Class ;
  rdfs:label "intranasal vaccination" ;
  rdfs:comment "vaccination process that occurs in intranasal route" ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0019888 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Solution [Flublok 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0003882 , obo:VO_0019886 .

obo:VO_0002601 a rdfs:Class ;
  rdfs:label "purM from Francisella tularensis" ;
  rdfs:comment "A purMCD mutant in Francisella tularensis was attenuated. A low dose of the F. tularensis LVS delta purMCD mutant provided protection against subsequent lethal challenge with the LVS parental strain" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0003605 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010317 , obo:VO_0010415 .

obo:VO_0004128 a rdfs:Class ;
  rdfs:label "Marburg virus glycoprotein expressed by baculovirus recombinants vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012163 .

obo:VO_0001379 a rdfs:Class ;
  rdfs:label "unvaccinated with a licensed vaccine" ;
  rdfs:comment "a unvaccinated quality that indicates an organism has not been vaccinated with a licensed vaccine." ;
  rdfs:subClassOf obo:VO_0001377 .

obo:VO_0007706 a rdfs:Class ;
  rdfs:label "MVF-HER-2(628-647)-CRL 1005 vaccine" ;
  rdfs:comment "A cancer vaccine of a chimeric peptide immunogen of human epidermal growth factor-2 (HER-2) with antineoplastic property. MVF-HER-2(628-647)-CRL 1005 vaccine, coated with poloxamer CRL-1005 to form microparticles, consists of a mutated HER-2 B-cell epitope, HER-2(628-647), and a promiscuous T cell epitope (amino acid sequence 288-302) of the measles virus fusion protein (MVF). The vaccine may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against tumor cells that overexpress the HER2 protein, resulting in tumor cell lysis. MVF-HER-2(628-647)-CRL 1005 vaccine may induce anti-HER-2 antibody in patients with metastatic or recurrent cancer (Breast, Ovarian, Non-small cell lung cancer, Gastric adenocarcinoma)." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0017297 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017246 .

obo:VO_0006006 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b vaccine conjugate unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010437 .

obo:VO_0003219 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 14 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0002890 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Enteritidis guaBA/clpP mutant vaccine" ;
  rdfs:comment "A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica" .

obo:VO_0001418 a rdfs:Class ;
  rdfs:label "Pasteurella multocida gene" ;
  rdfs:comment "A bacterial gene that is from Pasteurella multocida." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0010487 a rdfs:Class ;
  rdfs:label "licensed human vaccinia virus vaccine" ;
  rdfs:comment "Licensed human smallpox virus vaccine that uses vaccinia virus. " ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010452 .

obo:VO_0003833 a rdfs:Class ;
  rdfs:label "Havrix Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003826 .

obo:VO_0004042 a rdfs:Class ;
  rdfs:label "Sarcocystis neurona SAG1 Protein vaccine" ;
  rdfs:subClassOf obo:VO_0000935 .

obo:VO_0021001 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 UNT" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0007557 a rdfs:Class ;
  rdfs:label "Globo H-GM2-Lewis-y-MUC1-32-mer-TF(c)-Tn(c)-KLH conjugate vaccine" ;
  rdfs:comment "A multivalent vaccine comprised of the epitope antigens of Globo H hexasaccharide 1 (Globo H), GM2 ganglioside, Lewis-Y, MUC1-32-mer, TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin, with potential antineoplastic activity. The antigens included in this vaccine are associated various cancer cells. Vaccination with this multivalent vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0007657 .

obo:NCBITaxon_5691 a rdfs:Class ;
  rdfs:label "Trypanosoma brucei" ;
  rdfs:subClassOf obo:NCBITaxon_5690 .

obo:VO_0010444 a rdfs:Class ;
  rdfs:label "licensed human neisseria meningitidis vaccine" ;
  rdfs:comment "Neisseria meningitidis vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000635 .

obo:VO_0016850 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Covaxis] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016798 .

obo:VO_0010087 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii ROP18" ;
  rdfs:comment "A ROP18 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:DOID_8536 a rdfs:Class ;
  rdfs:label "herpes zoster"@en ;
  rdfs:comment "A viral infectious disease that results_in infection located_in nerve fiber, has_material_basis_in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The virus is transmitted_by direct contact with the rash, which can develop into chickenpox in newly-infected individuals. The infection has_symptom rash which is followed by blisters, has_symptom headache, has_symptom fever, has_symptom malaise, has_symptom itching, has_symptom burning pain, and has_symptom paresthesia."@en ;
  rdfs:subClassOf obo:DOID_863 , obo:DOID_934 .

obo:VO_0016574 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Twinrix Adult]" ;
  rdfs:subClassOf obo:VO_0016580 .

obo:VO_0018191 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0017639 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 20" ;
  rdfs:subClassOf obo:VO_0017631 .

obo:VO_0004090 a rdfs:Class ;
  rdfs:label "CCSV vaccine" ;
  rdfs:subClassOf obo:VO_0000651 .

obo:VO_0000842 a rdfs:Class ;
  rdfs:label "AquaVac ERM vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000645 , obo:VO_0001035 , obo:VO_0001477 .

obo:VO_0011285 a rdfs:Class ;
  rdfs:label "H1" ;
  rdfs:comment "Following infection with L. infantum promastigotes, five out of eight beagle dogs immunized with H1 Montanide remained free of clinical signs, compared to two out of eight dogs in the control group.  The results demonstrate that H1 antigens with Montanide were able to induce partial protection against canine leishmaniasis, even under extreme experimental challenge conditions [PubMed: 17576026]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010836 .

obo:VO_0000649 a rdfs:Class ;
  rdfs:label "licensed dog vaccine" ;
  rdfs:subClassOf obo:VO_0000363 , obo:VO_0001467 .

obo:VO_0010807 a rdfs:Class ;
  rdfs:label "Canine parvovirus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0005461 a rdfs:Class ;
  rdfs:label "influenza, high-dose seasonal, quadrivalent, 0.7ml dose, preservative free" ;
  rdfs:comment "A viral vaccine that protects against infection with influenza virus and with high-dose seasonal,quadrivalent,0.7ml dose,preservative free." ;
  rdfs:subClassOf obo:VO_0004673 .

obo:VO_0001533 a rdfs:Class ;
  rdfs:label "Pigeon Pox Live Virus Vaccine (USDA: 1881.14)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001220 , obo:VO_0001481 , obo:VO_0007748 .

obo:OGG_2000083332 a rdfs:Class ;
  rdfs:label "gene of Mycobacterium tuberculosis H37Rv" ;
  rdfs:comment "A gene of an organism of Mycobacterium tuberculosis H37Rv" ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0015550 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Hepasorbat]" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0021015 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution [Varilrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0021014 , obo:VO_0021017 .

obo:VO_0004781 a rdfs:Class ;
  rdfs:label "VC-TetC/Tcf vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:NCBITaxon_136 a rdfs:Class ;
  rdfs:label "Spirochaetales" ;
  rdfs:subClassOf obo:NCBITaxon_203692 .

obo:VO_0019128 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0020304 .

obo:VO_0011156 a rdfs:Class ;
  rdfs:label "Hsp70" ;
  rdfs:comment "Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani. Results demonstrated that liposomal LD72 (Hsp70) reduced parasite burden by 65%-67% [PubMed: 19503834]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0018019 a rdfs:Class ;
  rdfs:label "Poliomyelitis Virus Type 2 (Sabin Strain (P712, Ch, 2ab)) Live Attenuated Oral Vaccine 100000 UNT" ;
  rdfs:subClassOf obo:VO_0018018 .

obo:VO_0011540 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding NA from influenza B virus (B/Ibaraki/2/85)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0010708 a rdfs:Class ;
  rdfs:label "BCG vaccine (Freeze-Dried) (by Sanofi Pasteur)" ;
  rdfs:subClassOf obo:VO_0000714 , obo:VO_0000771 .

obo:VO_0017126 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017073 .

obo:VO_0018072 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 50" ;
  rdfs:subClassOf obo:VO_0018065 , obo:VO_0018080 , obo:VO_0018154 .

obo:VO_0003960 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis vaccine antigen" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0007165 a rdfs:Class ;
  rdfs:label "Recombinant Vaccinia-PSA/PSMA Vaccine" ;
  rdfs:comment "A recombinant vaccinia virus encoding prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) with potential use in cancer immunotherapy." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0019175 a rdfs:Class ;
  rdfs:label "0.5 ML hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015279 , obo:VO_0019502 .

obo:VO_0002617 a rdfs:Class ;
  rdfs:label "asd from Salmonella Typhimurium" ;
  rdfs:comment "An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0011317 a rdfs:Class ;
  rdfs:label "SpaP" ;
  rdfs:comment "Guinea pigs immunized with different doses of the SPA appear to be protected against challenge with live organisms as compared with nonimmunized controls [PubMed: 2122457]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010846 .

obo:VO_0002851 a rdfs:Class ;
  rdfs:label "obsolete Francisella tularensis purMCD mutant vaccine" ;
  rdfs:comment "A purMCD mutant in Francisella tularensis was attenuated. A low dose of the F. tularensis LVS delta purMCD mutant provided protection against subsequent lethal challenge with the LVS parental strain" .

obo:VO_0007380 a rdfs:Class ;
  rdfs:label "Falimarev vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a recombinant fowlpox viral vector encoding the carcinoembryonic antigen (CEA), MUC-1, a transmembrane glycoprotein secreted by glandular epithelial tissues, and TRICOM, comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3). This agent may enhance CEA and MUC-1 presentation to antigen-presenting cells (APC) and may activate a cytotoxic T-cell response against CEA- and MUC-1-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0020447 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10" ;
  rdfs:subClassOf obo:VO_0020410 , obo:VO_0020423 .

obo:VO_0017933 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0001214 , obo:VO_0017899 .

obo:VO_0020151 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003441 , obo:VO_0010444 , obo:VO_0010445 .

obo:VO_0018425 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II]" ;
  rdfs:subClassOf obo:VO_0018384 , obo:VO_0018394 .

obo:VO_0016128 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 50 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015880 .

obo:VO_0018414 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 6B vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003250 .

obo:VO_0010339 a rdfs:Class ;
  rdfs:label "AUDENZ vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0016649 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Bb Farma" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0003554 a rdfs:Class ;
  rdfs:label "Firmicutes vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0007105 a rdfs:Class ;
  rdfs:label "recombinant Vaccinia-multiepitope melanoma peptides-B7.1-B7.2 vaccine" ;
  rdfs:comment "A cancer vaccine consisting of an inactivated recombinant vaccinia virus encoding epitope peptides derived from melanoma-related HLA-A2-restricted tumor-associated antigens (TAAs), including Melan-A(27-35), gp100(280-288) and tyrosinase(1-9), and two co-stimulatory B7 proteins, B7.1 (CD80) and B7.2 (CD86). Upon administration, recombinant vaccinia-multiepitope melanoma peptides-B7.1-B7.2 vaccine may stimulate a cytotoxic T-lymphocyte response against melanoma cells that express TAAs which share epitopes with the epitope peptides expressed by the vaccine viral vector, resulting in tumor cell lysis; vaccine viral vector-expressed co-stimulatory proteins B7.1 and B7.2 may enhance the cytotoxic T-lymphocyte immune response to the TAAs." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0018312 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0018285 .

obo:VO_0010167 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b vaccine, PRP-T conjugate" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010437 .

obo:VO_0002575 a rdfs:Class ;
  rdfs:label "aroC from Burkholderia pseudomallei" ;
  rdfs:comment "The aroC deletion in the resultant mutant, designated A2ŒîaroC, was confirmed by PCR, Southern hybridization and failure of the mutant to grow in a defined medium without aromatic compounds. The constructed unmarked aroC mutant of B. pseudomallei is attenuated in both BALB/c and C57Bl/6 mice and is able to confer significant protection in C57Bl/6 mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001411 .

obo:VO_0000672 a rdfs:Class ;
  rdfs:label "heat-killed virulent Shigella flexneri 2a vaccine" ;
  rdfs:subClassOf obo:VO_0000680 , obo:VO_0001214 .

obo:VO_0000453 a rdfs:Class ;
  rdfs:label "prime boost regimen" ;
  rdfs:subClassOf obo:VO_0000572 .

obo:VO_0002360 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0000568 , obo:VO_0002358 .

obo:VO_0004392 a rdfs:Class ;
  rdfs:label "Brucella abortus DNA vaccine pcDNA3.1-p39-L7/L12 encoding p39-L7/L12 fusion protein" ;
  rdfs:subClassOf obo:VO_0001225 .

obo:VO_0016654 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Medicopharm" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0016441 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0003817 a rdfs:Class ;
  rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010311 , obo:VO_0010415 .

obo:VO_0020713 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1920000000 CFU Injection [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020711 , obo:VO_0020712 , obo:VO_0020741 .

obo:VO_0020278 a rdfs:Class ;
  rdfs:label "typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003849 .

obo:VO_0004942 a rdfs:Class ;
  rdfs:label "human age 19 to 26 years at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004929 .

obo:VO_0007439 a rdfs:Class ;
  rdfs:label "MiHA-loaded PD-L1/L2-silenced dendritic cell vaccine" ;
  rdfs:comment "A dendritic cell (DC)-based vaccine composed of program death ligands 1 and 2 (PDL1/L2)-silenced DCs and loaded with the recipient's minor histocompatibility antigens (MiHA), with potential use for graft-versus-tumor (GVT) induction following allogeneic stem cell transplantation (allo-SCT). Donor DCs are electroporated ex vivo with MiHA mRNA and small interfering RNAs (siRNAs) designed to silence the expression of PD L1/L2. After allo-SCT and upon intravenous administration of the MiHA-loaded PD-L1/L2-silenced DC vaccine, the DCs induce the expansion and activation of MiHA-specific CD8-positive T-cells. These tumor antigen-reactive T-cells exert their GVT effect by killing miHA-positive tumor cells. PD-L1/L2, co-inhibitory ligands expressed on DCs, play key roles in preventing MiHA-specific CD8-positive T-cell expansion; silencing enhances MiHA-specific CD8-positive T-cell expansion and activity and improves the GVT effect. The MiHA are human leukocyte antigen (HLA)-bound peptides and are exclusively expressed by the recipient's hematopoietic tumor cells." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0010717 a rdfs:Class ;
  rdfs:label "Imovax Rabies (Canada) vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000714 , obo:VO_0010448 .

obo:VO_0018779 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.0936 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010447 .

obo:VO_0010357 a rdfs:Class ;
  rdfs:label "Proquad (Frozen) vaccine" ;
  rdfs:subClassOf obo:VO_0000091 .

obo:VO_0002720 a rdfs:Class ;
  rdfs:label "gD from Herpes simplex virus type 1 and 2" ;
  rdfs:comment "KOS-gDA3C is attenuated with mutations in gD gene in causing skin lesions at the inoculation and zosteriform sites, yet it is as effective as rKOS-gDA3C in protecting mice against HSV-1 challenge" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001437 .

obo:VO_0018027 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 2000000 CELLS/ML" ;
  rdfs:subClassOf obo:VO_0003835 .

obo:VO_0019979 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Injectable Suspension [Afluria 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019978 , obo:VO_0020300 .

obo:VO_0000961 a rdfs:Class ;
  rdfs:label "live attenuated infectious bursal disease virus vaccine" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0001497 .

obo:VO_0000801 a rdfs:Class ;
  rdfs:label "vaccine storage at room temperature" ;
  rdfs:comment "a vaccine storage that is execuated at room temperature. Room temperature is also referred to as ambient temperature. Room temperature denotes a certain temperature within enclosed space at which humans are accustomed. Room temperature is usually indicated by general human comfort, with the common range of 10 degree C (50 degree F) to 28 degree C (82.4 degree F)." ;
  rdfs:subClassOf obo:VO_0000800 .

obo:VO_0020558 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Csl] Box of 10" ;
  rdfs:subClassOf obo:VO_0020557 , obo:VO_0020603 , obo:VO_0020862 .

obo:VO_0018903 a rdfs:Class ;
  rdfs:label "influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0017399 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection Box of 5" ;
  rdfs:subClassOf obo:VO_0017395 .

obo:VO_0016722 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0016707 , obo:VO_0016733 .

obo:VO_0017928 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.008 MG/ML / meningococcal group C polysaccharide 0.008 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.008 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.008 MG/ML Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0017891 .

obo:VO_0018700 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 TCID" ;
  rdfs:subClassOf obo:VO_0015054 .

obo:VO_0016401 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 3 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015960 , obo:VO_0015966 .

obo:VO_0016074 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015868 .

obo:VO_0020324 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2019-2020 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003067 , obo:VO_0010420 .

obo:VO_0015184 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015183 .

obo:VO_0016824 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0016733 , obo:VO_0016773 .

obo:VO_0010048 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum PfCelTOS" ;
  rdfs:comment "A PfCelTOS protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0001634 a rdfs:Class ;
  rdfs:label "Bursal Disease Killed Virus Vaccine (USDA: 1275.20)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000960 , obo:VO_0007748 .

obo:VO_0016322 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015934 .

obo:VO_0015244 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML [Vaqta]" ;
  rdfs:subClassOf obo:VO_0010745 , obo:VO_0015243 .

obo:VO_0002690 a rdfs:Class ;
  rdfs:label "guaB from Yersinia pestis" ;
  rdfs:comment "A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001426 .

obo:VO_0000174 a rdfs:Class ;
  rdfs:label "Leishmania gene" ;
  rdfs:subClassOf obo:VO_0000170 .

obo:VO_0000393 a rdfs:Class ;
  rdfs:label "Pseudomonas aeruginosa vaccine" ;
  rdfs:comment "bacterial vaccine that is used to protect against Pseudomonas aeruginosa infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000766 .

obo:VO_0011022 a rdfs:Class ;
  rdfs:label "APP7_1016" ;
  rdfs:comment "Following a booster vaccination, a significant (P < 0.05) IgG antibody response to the CP, LPS, and HP (APP7_1016) was detected in the vaccinated pigs. The pigs vaccinated with the CP-HP and LPS-HP conjugates exhibited significantly less mortality (P < 0.05) and significantly greater weight gain (P < 0.001) than unvaccinated pigs. Vaccinated pigs exhibited significantly fewer and less extensive gross pulmonary lesions (P < 0.001) when compared with unvaccinated pigs [PubMed: 1455686]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010821 .

obo:VO_0017237 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b / Hepatitis B Surface Antigen Vaccine / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000946 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0017799 .

obo:VO_0015019 a rdfs:Class ;
  rdfs:label "Engerix-B Injectable Product" ;
  rdfs:subClassOf obo:VO_0010711 .

obo:VO_0020146 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0017673 .

obo:VO_0011296 a rdfs:Class ;
  rdfs:label "T. cruzi TSA-1" ;
  rdfs:comment "Following the intramuscular immunization of H-2(b) and H-2(d) mice with a plasmid DNA encoding an N-terminally truncated TSA-1 lacking or containing the C-terminal nonapeptide tandem repeats, the antibody level, CTL response, and protection against challenge with T. cruzi were assessed. In H-2(b) mice, antiparasite antibodies were induced only by immunization with the DNA construct encoding TSA-1 containing the C-terminal repeats. However, both DNA constructs were efficient in eliciting long-lasting CTL responses against the protective H-2Kb-restricted TSA-1515-522 epitope. In H-2(d) mice, inoculation with either of the two TSA-1-expressing vectors effectively generated antiparasite antibodies and primed CTLs that lysed T. cruzi-infected cells in an antigen-specific, MHC class I-restricted, and CD8(+)-T-cell-dependent manner. When TSA-1 DNA-vaccinated animals were challenged with T. cruzi, 14 of 22 (64%) H-2(b) and 16 of 18 (89%) H-2(d) mice survived the infection [PubMed: 9784506]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:CHEBI_32111 a rdfs:Class ;
  rdfs:label "saccharin" ;
  rdfs:comment "A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0000934 a rdfs:Class ;
  rdfs:label "sorbitol vaccine stabilizer" ;
  rdfs:comment "a vaccine stabilizer that is specifically made by sorbitol." ;
  rdfs:subClassOf obo:VO_0003034 .

obo:VO_0015065 a rdfs:Class ;
  rdfs:label "prefilled syringe" ;
  rdfs:subClassOf obo:VO_0015062 .

obo:NCBITaxon_5874 a rdfs:Class ;
  rdfs:label "Theileria annulata" ;
  rdfs:subClassOf obo:NCBITaxon_5873 .

obo:VO_0004173 a rdfs:Class ;
  rdfs:label "pCAGGoptiHA vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0000353 a rdfs:Class ;
  rdfs:label "pWRM DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0017740 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML [Repevax]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0017802 .

obo:VO_0002645 a rdfs:Class ;
  rdfs:label "lppA from Salmonella Typhimurium" ;
  rdfs:comment "An lppA mutant, in combination with an lppB/msbB mutation, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0020118 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0015053 , obo:VO_0020120 .

obo:VO_0015689 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 50" ;
  rdfs:subClassOf obo:VO_0015565 , obo:VO_0015782 .

obo:VO_0015054 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010450 .

obo:NCBITaxon_210 a rdfs:Class ;
  rdfs:label "Helicobacter pylori" ;
  rdfs:subClassOf obo:NCBITaxon_213849 .

obo:VO_0000163 a rdfs:Class ;
  rdfs:label "vaccine-induced gene up-regulation controlling intracellular bacterial replication" ;
  rdfs:subClassOf obo:VO_0000569 .

obo:OPL_0000199 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum zygote stage" ;
  rdfs:comment "A zygote stage in the Plasmodium falciparum lifecycle that occurs in the midgut of the mosquito vector where a microgamete and a macrogamete fertilizes each other to produce a diploid cell." ;
  rdfs:subClassOf obo:OPL_0000165 , obo:OPL_0000307 , obo:UBERON_0000106 .

obo:VO_0007110 a rdfs:Class ;
  rdfs:label "Synchrovax SEM plasmid DNA vaccine" ;
  rdfs:comment "A bivalent DNA vaccine encoding epitopes for both Melan-A (MART-1) and tyrosinase with potential antineoplastic activity. Synchrovax SEM plasmid DNA vaccine contains a plasmid pSEM that encodes 4 epitopes: Melan-A (26-35), Melan-A (31-96), tyrosinase (1-9), and tyrosinase (369-377). Both Melan-A and tyrosinase are tumor antigens associated with melanoma. Vaccination with this plasmid DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) responses against cells expressing either or both of these antigens, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0003534 a rdfs:Class ;
  rdfs:label "Corynebacterium vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Corynebacterium." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0005450 a rdfs:Class ;
  rdfs:label "licensed human Rho(D) immune globulin- IV or IM passive vaccine" ;
  rdfs:subClassOf obo:VO_0005451 .

obo:VO_0019397 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000743 , obo:VO_0017799 .

obo:VO_0003245 a rdfs:Class ;
  rdfs:label "Recombivax Injectable Product" ;
  rdfs:subClassOf obo:VO_0010737 .

obo:VO_0004026 a rdfs:Class ;
  rdfs:label "Treponema pallidum Tp92 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001230 .

obo:VO_0000452 a rdfs:Class ;
  rdfs:label "preventive vaccine function" ;
  rdfs:comment "A vaccine function realized by the process of vaccination and leading to induction of an adaptive immune response to prevent a specific disorder." ;
  rdfs:subClassOf obo:VO_0000278 .

obo:VO_0003208 a rdfs:Class ;
  rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML" ;
  rdfs:subClassOf obo:VO_0003200 .

obo:VO_0005360 a rdfs:Class ;
  rdfs:label "chitosan vaccine adjuvant" ;
  rdfs:comment "A carbohydrate vaccine adjuvant that is aminoglycan consisting of beta-(1->4)-linked D-glucosamine residues." ;
  rdfs:subClassOf obo:VO_0001359 .

obo:VO_0019186 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020343 .

obo:VO_0015812 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015496 .

obo:VO_0020124 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML [Meningovax-AC]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017813 .

obo:VO_0001061 a rdfs:Class ;
  rdfs:label "Theileria parva vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0004680 a rdfs:Class ;
  rdfs:label "rNDV-ILTV-gD vaccine" ;
  rdfs:subClassOf obo:VO_0001488 .

obo:VO_0002484 a rdfs:Class ;
  rdfs:label "Mink Distemper-Enteritis vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001493 , obo:VO_0012178 .

obo:VO_0017553 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0017548 .

obo:VO_0004117 a rdfs:Class ;
  rdfs:label "Marburg virus-like particles vaccine" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0012163 .

obo:VO_0002628 a rdfs:Class ;
  rdfs:label "crp from Salmonella Typhimurium" ;
  rdfs:comment "A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0010731 a rdfs:Class ;
  rdfs:label "Pneumo 23" ;
  rdfs:comment "A polyvalent pneumococcal vaccine used to protectsagainst serious infection (e.g., meningitis, bacteria in the blood) due to Streptococcus pneumoniae, and it is manufactured by Sanofi Pasteur." ;
  rdfs:subClassOf obo:VO_0000424 .

obo:VO_0000330 a rdfs:Class ;
  rdfs:label "inedible" ;
  rdfs:comment "A quality of edibility that inheres in a bearer by virtue of the bearer being not suitable for oral ingestion." ;
  rdfs:subClassOf obo:VO_0000245 .

obo:VO_0010126 a rdfs:Class ;
  rdfs:label "host species variable" ;
  rdfs:comment "A variable representing the species of the host used for a study." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0002019 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 4570.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0000974 , obo:VO_0002375 .

obo:VO_0003673 a rdfs:Class ;
  rdfs:label "PedvaxHIB vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003671 , obo:VO_0020832 .

obo:NCBITaxon_430066 a rdfs:Class ;
  rdfs:label "Brucella abortus S19" ;
  rdfs:subClassOf obo:NCBITaxon_235 .

obo:VO_0000019 a rdfs:Class ;
  rdfs:label "pVAX DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016189 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:VO_0018527 a rdfs:Class ;
  rdfs:label "0.5 ML Anthrax Vaccine Adsorbed 0.1 MG/ML Injectable Suspension [Biothrax] by Emergent Sales And Marketing" ;
  rdfs:subClassOf obo:VO_0018525 , obo:VO_0018526 .

obo:VO_0007002 a rdfs:Class ;
  rdfs:label "Recombinant Fowlpox GM-CSF Vaccine Adjuvant" ;
  rdfs:comment "A cancer vaccine adjuvant consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF binds to specific cell surface receptors on various immuno-hematopoietic cell types, enhancing their proliferation and differentiation and stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Administration of recombinant fowlpox GM-CSF vaccine adjuvant may induce an immune response against tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0002758 a rdfs:Class ;
  rdfs:label "p36p from Plasmodium berghei" ;
  rdfs:comment "Genetically attenuated P36p-deficient Plasmodium berghei sporozoites provide protection against sporozoites challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001451 .

obo:VO_0017454 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide 0.02 MG/ML / tetanus toxoid vaccine, inactivated 0.04 MG/ML Injectable Suspension [Neisvac C]" ;
  rdfs:subClassOf obo:VO_0017453 .

obo:VO_0017470 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML [Tetanol]" ;
  rdfs:subClassOf obo:VO_0003385 .

obo:NCBITaxon_36420 a rdfs:Class ;
  rdfs:label "H1N1 swine influenza virus" ;
  rdfs:subClassOf obo:NCBITaxon_114727 .

obo:VO_0004342 a rdfs:Class ;
  rdfs:label "HIV DNA vaccine Ad26/Ad5HVR48 encoding HIV or SIV env or gag" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0016535 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by HVD" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0010981 a rdfs:Class ;
  rdfs:label "GNA1870" ;
  rdfs:comment "Protective antigen [PubMed: 16825336]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0017238 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b / Hepatitis B Surface Antigen Vaccine / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Suspension [HEXYON]" ;
  rdfs:subClassOf obo:VO_0017237 .

obo:VO_0000106 a rdfs:Class ;
  rdfs:label "vaccine-induced T cell mediated immunity" ;
  rdfs:subClassOf obo:VO_0010462 .

obo:VO_0019455 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Decavac]" ;
  rdfs:subClassOf obo:VO_0000030 , obo:VO_0019454 .

obo:NCBITaxon_64895 a rdfs:Class ;
  rdfs:label "Borreliella" ;
  rdfs:subClassOf obo:NCBITaxon_136 .

obo:VO_0010924 a rdfs:Class ;
  rdfs:label "OmpA from C. psittaci" ;
  rdfs:comment "The ompA codon was adapted to the codon usage in birds, resulting in pcDNA1/MOMP(opt).  Researchers examined the capacity of nebulised or intramuscularly (IM) administered brPEI-pcDNA1/MOMP(opt) to induce a significant protective immune response in SPF turkeys experimentally infected with 10^8 TCID(50) of a virulent Cp. psittaci strain.  Vaccinated groups were significantly protected against Cp. psittaci challenge [PubMed: 20199760]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010839 .

obo:VO_0000223 a rdfs:Class ;
  rdfs:label "pCMV-LacZ DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016707 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0016670 , obo:VO_0016680 , obo:VO_0016719 .

obo:VO_0020479 a rdfs:Class ;
  rdfs:label "Fluzone 2011-2012 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 , obo:VO_0010419 .

obo:VO_0004910 a rdfs:Class ;
  rdfs:label "PfSPZ vaccine by Sanaria Inc" ;
  rdfs:comment "A Plasmodium falciparum vaccine that is composed of aseptic, purified, live (metabolically active), radiation-attenuated, cryopreserved Plasmodium falciparum sporozite." ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0000571 a rdfs:Class ;
  rdfs:label "AAV vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses an AAV virus as the vector." ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0001684 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotype 1, Live Virus Vaccine (USDA: 16L1.04)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:NCBITaxon_11041 a rdfs:Class ;
  rdfs:label "Rubella virus" ;
  rdfs:subClassOf obo:NCBITaxon_11040 .

obo:VO_0007675 a rdfs:Class ;
  rdfs:label "hyperacute - breast cancer vaccine" ;
  rdfs:comment "A cancer vaccine composed of irradiated allogeneic breast cancer cell lines (HAB-1 and HAB-2) that have been transduced with a recombinant Moloney murine leukemia virus (MoMLV)-based retroviral vector expressing the murine alpha (1,3) GT gene. The immune response to the foreign substance could stimulate the immune system to attack the patient's own cancer cells that have similar proteins without this sugar pattern, causing the tumor to remain stable or shrink." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0003283 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Injection [Zostavax]" ;
  rdfs:subClassOf obo:VO_0003282 .

obo:VO_0018846 a rdfs:Class ;
  rdfs:label "oral capsule" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:VO_0017022 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 2" ;
  rdfs:subClassOf obo:VO_0016995 , obo:VO_0017499 .

obo:NCBITaxon_11099 a rdfs:Class ;
  rdfs:label "Bovine viral diarrhea virus 1" ;
  rdfs:subClassOf obo:NCBITaxon_11095 .

obo:VO_0010022 a rdfs:Class ;
  rdfs:label "Leishmania  infantum A2" ;
  rdfs:comment "A A2 protein that is part of Leishmania  infantum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010836 .

obo:VO_0018077 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0018052 , obo:VO_0018157 .

obo:VO_0016382 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 25 by Mtk" ;
  rdfs:subClassOf obo:VO_0015944 .

obo:VO_0002480 a rdfs:Class ;
  rdfs:label "Swine Influenza Vaccine-Mycoplasma Hyopneumoniae Bacterin" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000329 , obo:VO_0000563 , obo:VO_0002477 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0018408 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 23F vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003252 .

obo:VO_0011262 a rdfs:Class ;
  rdfs:label "Tat" ;
  rdfs:comment "HIV-1 DNA plasmids expressing Env, Gag and Tat, either alone or combined with the corresponding protein immunogens formulated in the MF59 adjuvant, resulted in protection against an experimental HIV-1 infection in C57Bl/6 mice [PubMed: 17707956]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010767 .

obo:VO_0016638 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0016621 .

obo:VO_0017353 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Dpt Vaccinol]" ;
  rdfs:subClassOf obo:VO_0017349 .

obo:VO_0010899 a rdfs:Class ;
  rdfs:label "Gp55" ;
  rdfs:comment "Intramuscular vaccination of pigs with immunoaffinity-purified E1 (gp55) in a double water-oil emulsion elicited high titers of neutralizing antibodies between 2 and 4 weeks after vaccination at the lowest dose tested (20 micrograms). The vaccinated pigs were completely protected against intranasal challenge with 100 50% lethal doses of HCV (Classical swine fever virus) strain Brescia [PubMed: 8350404]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010801 .

obo:VO_0018180 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain Injectable Solution [Attenuvax]" ;
  rdfs:subClassOf obo:VO_0000007 , obo:VO_0018179 .

obo:VO_0017619 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017616 , obo:VO_0017628 .

obo:VO_0004236 a rdfs:Class ;
  rdfs:label "rHA with IL-2 adjuvant vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0017786 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0017779 .

obo:VO_0019538 a rdfs:Class ;
  rdfs:label "human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML / human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML Injectable Suspension [Cervarix]" ;
  rdfs:subClassOf obo:VO_0018652 , obo:VO_0019537 .

obo:VO_0021163 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Quadracel]" ;
  rdfs:subClassOf obo:VO_0010736 .

obo:VO_0020285 a rdfs:Class ;
  rdfs:label "varicella-zoster virus vaccine live (Oka-Merck) strain 2700 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003275 .

obo:VO_0000263 a rdfs:Class ;
  rdfs:label "sodB(Ft) vaccine" ;
  rdfs:comment "sodBFt is a live vaccine strain mutant of Francisella tularensis with reduced Fe-superoxide dismutase gene expression. Ref: PMID:18692537." ;
  rdfs:subClassOf obo:VO_0000152 , obo:VO_0001217 .

obo:VO_0005385 a rdfs:Class ;
  rdfs:label "GLA-3M-052-LS vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0021123 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hawaii/70/2019 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Minnesota/41/2019 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0003272 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0020287 .

obo:NCBITaxon_644 a rdfs:Class ;
  rdfs:label "Aeromonas hydrophila" ;
  rdfs:subClassOf obo:NCBITaxon_642 .

obo:VO_0015714 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 50" ;
  rdfs:subClassOf obo:VO_0015571 , obo:VO_0015793 .

obo:VO_0017092 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017091 .

obo:VO_0019964 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluarix 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019944 .

obo:CHEBI_24431 a rdfs:Class ;
  rdfs:label "chemical entity" ;
  rdfs:comment "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0015776 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015595 .

obo:VO_0011059 a rdfs:Class ;
  rdfs:label "CAB049 putative penicillin-binding protein" ;
  rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.  CP #5 (Transglycolase/transpeptidase, CAB049 putative penicillin-binding protein) was significantly more protective than the genes encoding fewer than 50 amino acids (p-value of less than 0.05 when comparing lung weights).  The chlamydial loads generally tracked with protection and the most protective genes were significantly lower than in unvaccinated controls (p < 0.05 in the Mannhitney U-test for genes CP #1, 2, 4, 9, 10) [PubMed: 15811648]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:VO_0007563 a rdfs:Class ;
  rdfs:label "MUC-2-Globo H-KLH Conjugate Vaccine" ;
  rdfs:comment "Gene name: MUC2" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0017593 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML [Tetanus-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0017682 .

obo:VO_0018284 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003863 , obo:VO_0018270 .

obo:VO_0002226 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002403 , obo:VO_0007748 .

obo:VO_0019139 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019983 .

obo:VO_0017737 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / Haemophilus B Conjugate Vaccine / Hepatitis B Surface Antigen Vaccine Injection [Infanrix Hexa]" ;
  rdfs:subClassOf obo:VO_0017736 .

obo:VO_0015302 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015301 , obo:VO_0015304 .

obo:VO_0015238 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix]" ;
  rdfs:subClassOf obo:VO_0015236 , obo:VO_0015237 .

obo:VO_0019674 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003784 .

obo:VO_0002088 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12P5.E0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002384 , obo:VO_0007748 .

obo:VO_0020107 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine / L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine / L1 protein, human papillomavirus type 31 vaccine / L1 protein, human papillomavirus type 33 vaccine / L1 protein, human papillomavirus type 45 vaccine / L1 protein, human papillomavirus type 52 vaccine / L1 protein, human papillomavirus type 58 vaccine / L1 protein, human papillomavirus type 6 vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 .

obo:VO_0003187 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Poliovirus vaccine foreign to USA" ;
  rdfs:comment "A Diphtheria-Tetanus-Poliovirus vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0000943 , obo:VO_0003444 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0020162 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0020161 .

obo:VO_0007642 a rdfs:Class ;
  rdfs:label "melanoma-specific Melan-A/Mart-1 peptide + virus-like nanoparticles vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0004914 , obo:VO_0007657 .

obo:IAO_0000104 a rdfs:Class ;
  rdfs:label "plan specification"@en ;
  rdfs:comment "A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:VO_0005050 a rdfs:Class ;
  rdfs:label "p1012 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label p1012." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0020216 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.05 MG/ML / SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (BA.4/BA.5) 0.05 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0002782 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis leuD mutant vaccine" ;
  rdfs:comment "Deletion of leuD gene was shown to be highly attenuated. Immunocompetent BALB/c mice vaccinated with the DleuD auxotroph were protected as well as BCG in terms of survival following an intravenous or aerosol challenge with virulent M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0002929 a rdfs:Class ;
  rdfs:label "obsolete Shigella sonnei virG/senA/senB/msbB2 mutant vaccine" ;
  rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" .

obo:VO_0011361 a rdfs:Class ;
  rdfs:label "Bordetella pertussis PTx protein vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0001034 a rdfs:Class ;
  rdfs:label "parasite vaccine vector" ;
  rdfs:comment "a vaccine vector that uses a parasite as the vector." ;
  rdfs:subClassOf obo:VO_0000599 .

obo:VO_0003009 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii p36/p52 mutant vaccine" ;
  rdfs:comment "A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites" ;
  rdfs:subClassOf obo:VO_0002514 .

obo:OPL_0000379 a rdfs:Class ;
  rdfs:label "Sarcocystis neurona lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Sarcocystis neurona." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:NCBITaxon_32561 a rdfs:Class ;
  rdfs:label "Sauria" ;
  rdfs:subClassOf obo:NCBITaxon_32524 .

obo:VO_0012184 a rdfs:Class ;
  rdfs:label "Trypanosoma brucei vaccine" ;
  rdfs:comment "A vaccine that protects against Trypanosoma brucei." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0019555 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020306 .

obo:VO_0018306 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT Injection" ;
  rdfs:subClassOf obo:VO_0018268 .

obo:VO_0000421 a rdfs:Class ;
  rdfs:label "Brucella abortus pcDNA-BLS" ;
  rdfs:subClassOf obo:VO_0001225 .

obo:VO_0007748 a rdfs:Class ;
  rdfs:label "USA licensed veterinary vaccine" ;
  rdfs:comment "USA licensed vaccine for veterinary uses approved by USDA. " ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001485 .

obo:OPL_0000289 a rdfs:Class ;
  rdfs:label "Plasmodium gametocyte stage" ;
  rdfs:comment "A gametocyte stage in the lifecycle of Plasmodium." ;
  rdfs:subClassOf obo:OPL_0000150 , obo:OPL_0000181 .

obo:CHEBI_16412 a rdfs:Class ;
  rdfs:label "lipopolysaccharide" ;
  rdfs:comment "Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria)." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0005371 a rdfs:Class ;
  rdfs:label "Pam3Cys vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant includes three palmitic acid groups that are bound in an ester and amide linkage to a cysteine residue." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0000133 a rdfs:Class ;
  rdfs:label "Freund's emulsified oil adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant that consists of a water-in-oil emulsion of aqueous antigen in paraffin (mineral) oil of low specific gravity and low viscosity. It is named after Jules T. Freund (1890-1960), Hungarian-born American immunologist. It is a water in oil emulsion." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0004015 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding HA from influenza A virus (A/Hong Kong/1/68(H3N2))" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0001769 a rdfs:Class ;
  rdfs:label "equine influenza killed virus vaccine (USDA: 1505.10)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0001176 , obo:VO_0003143 , obo:VO_0007748 .

obo:OPL_0000244 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum erythrocytic trophozoite" ;
  rdfs:comment "A Plasmodium falciparum trophozoite that is found in erythrocytes. It is a feeding stage with a single nucleus." ;
  rdfs:subClassOf obo:OPL_0000146 , obo:OPL_0000282 .

obo:VO_0000769 a rdfs:Class ;
  rdfs:label "Shigella vaccine" ;
  rdfs:comment "Vaccine that protects against Shigella species infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003552 .

obo:BFO_0000142 a rdfs:Class ;
  rdfs:label "one-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:VO_0019386 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection [Quadracel]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000943 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0003825 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010317 , obo:VO_0010415 .

obo:NCBITaxon_379584 a rdfs:Class ;
  rdfs:label "Caniformia" ;
  rdfs:subClassOf obo:NCBITaxon_33554 .

obo:VO_0017013 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 2 by Novartis" ;
  rdfs:subClassOf obo:VO_0017011 .

obo:VO_0019291 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Afluria 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020301 .

obo:VO_0018341 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003334 .

obo:VO_0010816 a rdfs:Class ;
  rdfs:label "Streptococcus equi protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:VO_0005070 a rdfs:Class ;
  rdfs:label "pCMV-beta DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCMV-beta.  This plasmid is 7164 base pairs in length and contains a CMV promoter and ampicllin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000218 a rdfs:Class ;
  rdfs:label "hypersensitivity to chicken egg" ;
  rdfs:subClassOf obo:VO_0000213 .

obo:VO_0016628 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0016607 , obo:VO_0016616 .

obo:VO_0016755 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Pediacel] Box of 10" ;
  rdfs:subClassOf obo:VO_0016716 , obo:VO_0016777 .

obo:VO_0019791 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0020376 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 10000000000 UNT Oral Powder [Vivotif]" ;
  rdfs:subClassOf obo:VO_0003353 , obo:VO_0003446 .

obo:UBERON_0002072 a rdfs:Class ;
  rdfs:label "hypodermis" ;
  rdfs:comment "Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]." ;
  rdfs:subClassOf obo:UBERON_0000064 , obo:UBERON_0004120 .

obo:NCBITaxon_5762 a rdfs:Class ;
  rdfs:label "Naegleria gruberi" ;
  rdfs:subClassOf obo:NCBITaxon_5761 .

obo:VO_0000714 a rdfs:Class ;
  rdfs:label "Canada licensed human vaccine" ;
  rdfs:comment "a licensed human vaccine that is licensed in Canada" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000635 .

obo:VO_0007339 a rdfs:Class ;
  rdfs:label "autologous dendritic cell vaccine loaded with personalized peptide vaccine (pep-dc vaccine)" ;
  rdfs:comment "A cancer vaccine made of dendritic cells (DCs) loaded with personalized peptides (PEP) given in combination with low-dose cyclophosphamide for patients with advanced or recurrent metastatic NSCLC." ;
  rdfs:subClassOf obo:VO_0003140 , obo:VO_0007657 , obo:VO_0007658 .

obo:DOID_11077 a rdfs:Class ;
  rdfs:label "brucellosis"@en ;
  rdfs:comment "A primary bacterial infectious disease that is caused by the bacteria of the genus Brucella, when humans come in contact with contaminated animals or animal products or ingestion of infected food products. The disease has_symptom fever, has_symptom sweat, has_symptom headache, has_symptom back pain, has_symptom physical weakness, has_symptom joint pain and has_symptom fatigue."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:VO_0003887 a rdfs:Class ;
  rdfs:label "Flublok 2015-2016 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003886 .

obo:VO_0010050 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum LSA1" ;
  rdfs:comment "A LSA1 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0017569 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis] Box of 20" ;
  rdfs:subClassOf obo:VO_0017567 , obo:VO_0017578 .

obo:VO_0019099 a rdfs:Class ;
  rdfs:label "delayed release oral capsule" ;
  rdfs:subClassOf obo:VO_0018846 .

obo:VO_0011414 a rdfs:Class ;
  rdfs:label "Entamoeba histolytica CEL-170/4 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012171 .

obo:DOID_0060100 a rdfs:Class ;
  rdfs:label "musculoskeletal system cancer"@en ;
  rdfs:comment "An organ system cancer located_in the muscular and skeletal organs and characterized by uncontrolled cellular proliferation of the musculoskeletal organs."@en ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_17 .

obo:VO_0015700 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015569 , obo:VO_0015789 .

obo:VO_0019448 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 25 LFU/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0017227 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017799 .

obo:VO_0017033 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017032 , obo:VO_0017044 , obo:VO_0017508 .

obo:VO_0016337 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0000972 a rdfs:Class ;
  rdfs:label "LHRH" ;
  rdfs:subClassOf obo:FMA_12278 .

obo:VO_0010761 a rdfs:Class ;
  rdfs:label "Ebola virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0019605 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020306 .

obo:VO_0019671 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019670 , obo:VO_0020483 .

obo:VO_0004894 a rdfs:Class ;
  rdfs:label "quadrivalent seasonal inactivated influenza vaccine 2014" ;
  rdfs:comment "quadrivalent seasonal inactivated influenza vaccine 2014 consisting of Influenza A virus (A/California/7/2009(H1N1)), Influenza A virus (A/Texas/50/2012(H3N2)), Influenza B virus (B/Brisbane/60/2008), Influenza B virus (B/Massachusetts/02/2012)" ;
  rdfs:subClassOf obo:VO_0001176 .

obo:VO_0017133 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017129 , obo:VO_0017597 .

obo:VO_0020507 a rdfs:Class ;
  rdfs:label "rubella virus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0016494 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Veron" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0016430 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0016024 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015665 , obo:VO_0015771 .

obo:CHEBI_16842 a rdfs:Class ;
  rdfs:label "formaldehyde" ;
  rdfs:comment "An aldehyde resulting from the formal oxidation of methanol." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0001214 a rdfs:Class ;
  rdfs:label "inactivated bacterial vaccine" ;
  rdfs:comment "Bacterial vaccine that uses inactivated bacterial organism. " ;
  rdfs:subClassOf obo:VO_0000165 , obo:VO_0000315 .

obo:VO_0004187 a rdfs:Class ;
  rdfs:label "Measles Virus vaccine VEE/SIN-H" ;
  rdfs:subClassOf obo:VO_0000654 .

obo:VO_0015860 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015612 , obo:VO_0015678 , obo:VO_0015988 .

obo:VO_0010710 a rdfs:Class ;
  rdfs:label "Dukoral vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000944 , obo:VO_0010455 .

obo:VO_0016066 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0015864 .

obo:VO_0000834 a rdfs:Class ;
  rdfs:label "recombinant Yersinia pestis YopD protein vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000648 .

obo:VO_0000075 a rdfs:Class ;
  rdfs:label "pBI/tTA DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0010137 a rdfs:Class ;
  rdfs:label "Respiratory syncytial virus (RSV) monoclonal antibody, IgG1κ, (nirsevimab-alip), 0.5 mL, neonates and children to 24 months" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000755 .

obo:VO_0005016 a rdfs:Class ;
  rdfs:label "SINCp B-gal DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label SINCp B-gal.  This plasmid contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002708 a rdfs:Class ;
  rdfs:label "UL23 from Feline herpesvirus 1" ;
  rdfs:comment "A thymidine kinase-deficient mutant (C7301dlTK) is attenuated in cats and induced significant protection from wild type FHV-1 4 weeks after vaccination" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001432 .

obo:VO_0000064 a rdfs:Class ;
  rdfs:label "Infanrix vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000714 , obo:VO_0000738 , obo:VO_0001214 .

obo:OPL_0000110 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum erythrocytic schizont" ;
  rdfs:comment "A Plasmodium falciparum schizont that is found in infected erythrocytes of a human host." ;
  rdfs:subClassOf obo:OPL_0000060 , obo:OPL_0000276 .

obo:VO_0001229 a rdfs:Class ;
  rdfs:label "Schistosoma japonicum vaccine" ;
  rdfs:comment "A protozoan vaccine that protects against infection with Schistosoma japonicum" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003047 .

obo:VO_0019527 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.02 MG/ML [HB-VAX]" ;
  rdfs:subClassOf obo:VO_0003256 .

obo:VO_0003194 a rdfs:Class ;
  rdfs:label "Spring Summer Encephalitis vaccine" ;
  rdfs:comment "A tick-borne encephalitis virus vaccine used to prevent subtype Far Eastern tick-borne encephalitis virus (formerly known as Russian Spring Summer encephalitis virus)." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010454 .

obo:VO_0019125 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0018455 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 10" ;
  rdfs:subClassOf obo:VO_0018432 , obo:VO_0018439 .

obo:VO_0002242 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47C5.29)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002398 , obo:VO_0007748 .

obo:VO_0001782 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis Modified Live Virus Vaccine (USDA: 1521.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001486 , obo:VO_0007748 .

obo:VO_0016292 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0016026 .

obo:VO_0018273 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003857 .

obo:VO_0010884 a rdfs:Class ;
  rdfs:label "CopN" ;
  rdfs:comment "Results of this study showed that intranasal immunization of BALB/c mice with heat-aggregated CopN protein and an Escherichia coli heat-labile toxin (LT) induced a strong immune response.  The immunization induced statistically significant protection against intranasal C. pneumoniae challenge, the level of which correlated with the magnitude of CopN-specific lymphocyte proliferation [PubMed: 16949182]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010794 .

obo:VO_0001609 a rdfs:Class ;
  rdfs:label "Avian Reovirus Killed Virus Vaccine (USDA: 1045.30)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001513 , obo:VO_0007748 .

obo:VO_0006051 a rdfs:Class ;
  rdfs:label "rotavirus live tetravalent vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010449 .

obo:VO_0015826 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015622 , obo:VO_0015623 .

obo:VO_0001199 a rdfs:Class ;
  rdfs:label "pathogen challenge datum" ;
  rdfs:comment "A measurement datum that represents a specific pathogen used for animal challenge study. Different pathogens can be represented using discretized digitals.  " ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0006107 a rdfs:Class ;
  rdfs:label "cowpea mosaic virus vaccine adjuvant" ;
  rdfs:comment "A particulate antigen delivery system vaccine adjuvant derived from Cowpea mosaic virus that is able to induce a Th1-biased response." ;
  rdfs:subClassOf obo:VO_0001356 .

obo:RO_0001000 a rdf:Property ;
  rdfs:label "derives from"@en ;
  rdfs:comment "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0001361 a rdfs:Class ;
  rdfs:label "virmugen role" ;
  rdfs:comment "a role that is inherenced in a gene that can be mutated in a virulent pathogen, leading to an attenuated strain serving as a live attenuated vaccine strain." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0016306 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by MSD" ;
  rdfs:subClassOf obo:VO_0015926 .

obo:VO_0001150 a rdfs:Class ;
  rdfs:label "enhanced significant protection" ;
  rdfs:subClassOf obo:VO_0000247 .

obo:VO_0001731 a rdfs:Class ;
  rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001019 , obo:VO_0007748 .

obo:VO_0007598 a rdfs:Class ;
  rdfs:label "DEPDC1/MPHOSH1 peptide vaccine" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0000657 a rdfs:Class ;
  rdfs:label "licensed bird vaccine" ;
  rdfs:subClassOf obo:VO_0000363 , obo:VO_0001461 .

obo:VO_0015909 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Fendrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015625 , obo:VO_0015759 , obo:VO_0016020 .

obo:VO_0001962 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4465.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002364 .

obo:VO_0005426 a rdfs:Class ;
  rdfs:label "colorectal cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is used against colorectal cancer" ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0017446 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injectable Solution [Hiberix]" ;
  rdfs:subClassOf obo:VO_0010715 , obo:VO_0017445 .

obo:VO_0001312 a rdfs:Class ;
  rdfs:label "Rehydragel LV vaccine adjuvant" ;
  rdfs:comment "An aluminum hydroxide vaccine adjuvant that is a low visosity aluminum hydroxide gel." ;
  rdfs:subClassOf obo:VO_0000127 .

obo:OPL_0000402 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii gametocyte stage" ;
  rdfs:comment "A gametocyte stage in the Plasmodium yoelii." ;
  rdfs:subClassOf obo:OPL_0000150 , obo:OPL_0000289 , obo:OPL_0000415 .

obo:VO_0015983 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015647 , obo:VO_0015761 , obo:VO_0016061 .

obo:VO_0015765 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [VACCIN GENHEVAC B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015585 , obo:VO_0015819 .

obo:VO_0004769 a rdfs:Class ;
  rdfs:label "rORFV-p40(Borna disease virus) vaccine" ;
  rdfs:subClassOf obo:VO_0001483 .

obo:VO_0002136 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002395 , obo:VO_0007748 .

obo:VO_0011076 a rdfs:Class ;
  rdfs:label "TUL4" ;
  rdfs:comment "A 17-kDa lipoprotein, TUL4, of the facultative intracellular bacterium Francisella tularensis is one of several membrane proteins that induce an in vitro response in T cells from F. tularensis-primed humans.  When mice were immunized with S. typhimurium chi 4072(pTUL4-15), some animals showed an antibody response and a T-cell response to TUL4.  The present study demonstrated that the 17-kDa lipoprotein TUL4 of F. tularensis is involved in a protective immunity to tularemia [PubMed: 1612751]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:VO_0002215 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002411 , obo:VO_0007748 .

obo:VO_0017808 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000765 , obo:VO_0010435 .

obo:VO_0011510 a rdfs:Class ;
  rdfs:label "Cancer Subunit DC (Tat-CEA) vaccine" ;
  rdfs:comment "Gene name: CEACAM3" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0005497 a rdfs:Class ;
  rdfs:label "head and neck cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against head and neck cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0019228 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020346 .

obo:VO_0003720 a rdfs:Class ;
  rdfs:label "Afluria 2015-2016 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003719 .

obo:VO_0002963 a rdfs:Class ;
  rdfs:label "obsolete Feline infectiour peritonitis virus 3abc mutant vaccine" ;
  rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" .

obo:VO_0019109 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe [Fluzone Intradermal 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019107 , obo:VO_0020487 .

obo:VO_0004349 a rdfs:Class ;
  rdfs:label "HIV DNA vaccine SIVmac239 Gag-Pol-Nef and mock Env with rAd5 boost" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0004663 a rdfs:Class ;
  rdfs:label "rMVA-GnGc (Rift Valley fever virus) vaccine" ;
  rdfs:subClassOf obo:VO_0012166 .

obo:VO_0001184 a rdfs:Class ;
  rdfs:label "vaccine protection ANOVA" ;
  rdfs:subClassOf obo:OBI_0200201 .

obo:VO_0015024 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Tenivac]" ;
  rdfs:subClassOf obo:VO_0000102 .

obo:VO_0005307 a rdfs:Class ;
  rdfs:label "TLR2 receptor role" ;
  rdfs:comment "A role of a material entity that binds to TLR2 and activates the receptor for pathogen recognition and activation of innate immunity." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0007717 a rdfs:Class ;
  rdfs:label "P30-linked EphA2/CMV pp65/survivin peptide vaccine P30-EPS" ;
  rdfs:comment "A cancer vaccine comprised of three immunogenic tetanus toxoid epitope P30-linked tumor-associated antigen (TAA) peptides, P30-linked Ephrin receptor A2 (EphA2), P30-linked cytomegalovirus (CMV) matrix protein pp65 (65 kDa lower matrix phosphoprotein; UL83) and P30-linked survivin, with potential immunostimulating and antineoplastic activities. The vaccine may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing EphA2, CMV pp65 and survivin. Hiltonol is used as an adjuvant to stimulate or enhance the activation of your immune system. The vaccine and adjuvant may help treat HLA-A*0201 positive patients with a newly diagnosed, unmethylated, and untreated World Health Organization (WHO) grade IV malignant glioma." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0017286 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection Box of 5" ;
  rdfs:subClassOf obo:VO_0017283 .

obo:VO_0019737 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Afluria Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0020306 .

obo:VO_0016701 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0015989 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015485 , obo:VO_0015773 .

obo:VO_0000472 a rdfs:Class ;
  rdfs:label "nontypeable Haemophilus influenzae" ;
  rdfs:comment "Nontypeable Haemophilus influenzae (NTHi) is a nonencapsulated Haemophilus influenzae (a gram-negative bacterium). It is the cause of a number of human respiratory tract diseases, such as otitis media, sinusitis, bronchitis, and pneumonia." ;
  rdfs:subClassOf obo:NCBITaxon_727 .

obo:VO_0021130 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0016884 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0016877 .

obo:VO_0000002 a rdfs:Class ;
  rdfs:label "vaccination" ;
  rdfs:comment "Process of administering a vaccine in vivo to a recipient (e.g., a human), with the intent to invoke a protective or therapeutic adaptive immune response." ;
  rdfs:subClassOf obo:OBI_0600007 .

obo:VO_0011475 a rdfs:Class ;
  rdfs:label "Theileria parva vaccine by Centre for Ticks and Tickborne Disease, Malawi" ;
  rdfs:subClassOf obo:VO_0001061 .

obo:VO_0000507 a rdfs:Class ;
  rdfs:label "obsolete Canada licensed veterinary vaccine role" ;
  rdfs:comment "A Canada  licensed vaccine role that indicates the vaccine is for veterinary uses." .

obo:NCBITaxon_715 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae" ;
  rdfs:subClassOf obo:NCBITaxon_712 .

obo:VO_0003465 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0010745 .

obo:VO_0018622 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension [Ixiaro] Box of 1" ;
  rdfs:subClassOf obo:VO_0018621 , obo:VO_0018623 .

obo:VO_0021128 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0010098 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA6" ;
  rdfs:comment "A GRA6 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0018596 a rdfs:Class ;
  rdfs:label "Bacillus anthracis Injectable Suspension [Biothrax]" ;
  rdfs:subClassOf obo:VO_0000014 , obo:VO_0018595 , obo:VO_0019409 .

obo:VO_0011145 a rdfs:Class ;
  rdfs:label "Envelope protein" ;
  rdfs:comment "Researchers constructed a recombinant pseudotype baculovirus encoding the JEV envelope (E) protein and demonstrated that it could elicit high protective immunity in mice.  Intramuscular injections of BV-G-E at various doses into mice produced higher levels of JEV-specific neutralizing antibodies, IFN-gamma and better protective efficacy against a lethal challenge with JEV than that of pc-E. Furthermore, BV-G-E could elicit a higher level of cellular immunity response and provide equal protective efficacy against JEV challenge compared to inactivated vaccine [PubMed: 19006097]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010783 .

obo:VO_0017193 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol] Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0017192 .

obo:VO_0016585 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016578 .

obo:VO_0018675 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 Powder for Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0018673 , obo:VO_0018674 , obo:VO_0018699 .

obo:VO_0011403 a rdfs:Class ;
  rdfs:label "Topografov virus N protein vaccine" ;
  rdfs:subClassOf obo:VO_0012167 .

obo:VO_0002294 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4975.22)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002462 , obo:VO_0007748 .

obo:VO_0002005 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica Toxoid (USDA: 4X49.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002369 .

obo:VO_0015151 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0000853 a rdfs:Class ;
  rdfs:label "vaccine stabilizer" ;
  rdfs:comment "Vaccine additive that helps to protect the vaccine from adverse conditions such as the freeze-drying process (for those vaccines that are freeze-dried) or heat." ;
  rdfs:subClassOf obo:VO_0000179 , obo:VO_0000850 .

obo:VO_0005165 a rdfs:Class ;
  rdfs:label "AG0301-COVID19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 DNA vaccine developed by AnGes, named as AG0301-COVID19." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0015473 a rdfs:Class ;
  rdfs:label "Plasmodium vivax protein" ;
  rdfs:subClassOf obo:VO_0010771 .

obo:VO_0010230 a rdfs:Class ;
  rdfs:label "tuberculin skin test; old tuberculin, multipuncture device" ;
  rdfs:subClassOf obo:NCIT_C85994 .

obo:VO_0000804 a rdfs:Class ;
  rdfs:label "effectiveness" ;
  rdfs:comment "Effectiveness is physical quality that represents the capability of a single physical entity (e.g., vaccine) producing an effect (e.g, protection against a disease)." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:VO_0004301 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pRSV-NP encoding the coding sequence from influenza virus A/PR/8/34." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0004263 a rdfs:Class ;
  rdfs:label "MVA/IL-15/5Mtb vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0002924 a rdfs:Class ;
  rdfs:label "Shigella flexneri envZ mutant vaccine" ;
  rdfs:comment "An envZ mutant (SC433) is greatly decreased in virulence in macaque monkeys, though some mild clinical signs were still recorded. This mutant is also highly protective against a challenge of wild type S. flexneri delivered 1 month after inoculation" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0011295 a rdfs:Class ;
  rdfs:label "CP cysteine proteinase" ;
  rdfs:comment "A 500 bp fragment encoding an isoform of cysteine proteinase (CP) from Leishmania (Leishmania) amazonensis was subcloned and expressed in the pHis vector, resulting in a recombinant protein of 24 kDa, rLacys24.  Immunization of BALB/c mice with rLacys24 plus CFA adjuvant resulted in a low but significant decrease of foot lesions after challenge with L. (L.) amazonensis compared to those exhibited by control mice [PubMed: 19735658]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010837 .

obo:VO_0000487 a rdfs:Class ;
  rdfs:label "typhoid live oral vaccine" ;
  rdfs:comment "a S. typhi vaccine that is live and orally administerred" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0010451 .

obo:VO_0018635 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003948 , obo:VO_0018611 .

obo:VO_0002221 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46E5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002390 , obo:VO_0007748 .

obo:CHEBI_17716 a rdfs:Class ;
  rdfs:label "lactose" ;
  rdfs:comment "A glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-1->4 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0004031 a rdfs:Class ;
  rdfs:label "Listeria monocytogenes DNA vaccine encoding hly" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002500 .

obo:VO_0016429 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0020248 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.008 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML [Prevnar]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0003031 a rdfs:Class ;
  rdfs:label "susceptibility gene response to vaccine adverse event" ;
  rdfs:comment "a vaccine-induced gene response that represents a vaccine adverse event response associated with a host susceptibility gene." ;
  rdfs:subClassOf obo:VO_0000286 .

obo:NCBITaxon_117565 a rdfs:Class ;
  rdfs:label "Myxini" ;
  rdfs:subClassOf obo:NCBITaxon_7742 .

obo:VO_0017864 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.004 MG" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0015237 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015235 .

obo:VO_0001429 a rdfs:Class ;
  rdfs:label "Bovine Respiratory Syncytial Virus gene" ;
  rdfs:comment "A viral gene that is from Bovine Respiratory Syncytial Virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:GO_0071738 a rdfs:Class ;
  rdfs:label "IgD immunoglobulin complex" ;
  rdfs:comment "A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ;
  rdfs:subClassOf obo:GO_0019814 .

obo:VO_0002260 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4847.24)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000542 , obo:VO_0000640 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0007748 .

obo:VO_0017250 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0017808 .

obo:VO_0001667 a rdfs:Class ;
  rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.58)" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:NCBITaxon_10310 a rdfs:Class ;
  rdfs:label "Human alphaherpesvirus 2" ;
  rdfs:subClassOf obo:NCBITaxon_10294 .

obo:VO_0007095 a rdfs:Class ;
  rdfs:label "NY-ESO-1/MART-1 peptide-pulsed dendritic cell vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of dendritic cells (DC) pulsed with peptides derived from the tumor-associated antigens human cancer/testis antigen NY-ESO-1 and melanoma antigen recognized by T-cells (MART-1/Melan-A), with potential immunostimulatory and antineoplastic activities. Upon administration, the NY-ESO-1/MART-1 peptide-pulsed DC vaccine may stimulate the immune system to mount an anti-tumor cytotoxic T-lymphocyte (CTL) response against NY-ESO-1/MART-1-expressing tumor cells, which may result in tumor cell lysis. NY-ESO-1 is expressed both in normal testes and on the surfaces of various tumor cells. MART-1 is expressed by melanoma cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0002231 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002400 , obo:VO_0007748 .

obo:VO_0017513 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0017506 .

obo:VO_0018749 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Injection [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0018747 .

obo:VO_0000752 a rdfs:Class ;
  rdfs:label "West Nile virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against West Nile virus infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003546 .

obo:NCBITaxon_260964 a rdfs:Class ;
  rdfs:label "Henipavirus" ;
  rdfs:subClassOf obo:NCBITaxon_2560076 .

obo:VO_0020313 a rdfs:Class ;
  rdfs:label "Fluad Quadrivalent 2022-2023 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0000548 a rdfs:Class ;
  rdfs:label "human vaccinee population at age 2-17 years old" ;
  rdfs:subClassOf obo:VO_0000545 .

obo:VO_0000829 a rdfs:Class ;
  rdfs:label "Yersinia pestis F1 protein vaccine" ;
  rdfs:comment "A Yersinia pestis subunit vaccine that uses Y. pestis F1 protein as antigen." ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0003968 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML [Heplisav-B]" ;
  rdfs:subClassOf obo:VO_0003152 , obo:VO_0003230 .

obo:CL_0000766 a rdfs:Class ;
  rdfs:label "myeloid leukocyte" ;
  rdfs:comment "A cell of the monocyte, granulocyte, or mast cell lineage." ;
  rdfs:subClassOf obo:CL_0000738 , obo:CL_0000763 .

obo:VO_0007560 a rdfs:Class ;
  rdfs:label "HLA-A*0201-Restricted VEGFR1 peptide vaccine" ;
  rdfs:comment "A cancer vaccine containing an HLA-A*0201-restricted vascular endothelial growth factor receptor 1 (VEGFR1) peptide (sequence: TLFWLLLTL) with potential immunostimulatory and antitumor activities. Upon administration, HLA-A*0201-restricted VEGFR1-derived peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing VEGFR1, resulting in tumor cell lysis and decreased tumor growth. HLA-A*0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005430 , obo:VO_0005484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0020688 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0000868 , obo:VO_0004914 .

obo:VO_0002862 a rdfs:Class ;
  rdfs:label "Pasteurella multocida aroA mutant vaccine" ;
  rdfs:comment "An aroA mutant is highly attenuated in calves and induces significant protection from challenge with wild type P. multocida" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0016457 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015975 .

obo:VO_0018205 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Solution" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0003418 , obo:VO_0010441 .

obo:VO_0017443 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.08 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0017440 , obo:VO_0020832 .

obo:VO_0004863 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0004860 .

obo:VO_0002424 a rdfs:Class ;
  rdfs:label "horse encephalomyelitis EEV, VEV, and WEV combination vaccine" ;
  rdfs:comment "a viral vaccine against horse EEV, WEV, and VEE viral infections" ;
  rdfs:subClassOf obo:VO_0000641 , obo:VO_0001472 , obo:VO_0001498 , obo:VO_0001499 , obo:VO_0012188 .

obo:VO_0011188 a rdfs:Class ;
  rdfs:label "TA17050 merozoite-piroplasm surface antigen Tams1" ;
  rdfs:comment "To test the potential of subunit vaccines against T. annulata infection, we immunized four groups of three calves with either recombinant (re-) (Tams1-1 and Tams1-2) proteins or naked DNA encoding these antigens. All calves vaccinated with ISCOMs proved to be protected from T. annulata infection and had generated antibodies against both re-(Tams1-1 and Tams1-2) at the time of challenge [PubMed: 9364686]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010825 .

obo:VO_0002935 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica aroA mutant vaccine" ;
  rdfs:comment "An aroA mutant is highly attenuated in mice, and after 3 doses induces significant protection from challenge with wild type Y. enterocolitica" ;
  rdfs:subClassOf obo:VO_0012186 .

obo:VO_0017074 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017556 .

obo:VO_0017380 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [Diftavax]" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0019750 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0016418 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 3 by Mtk" ;
  rdfs:subClassOf obo:VO_0015960 , obo:VO_0015966 .

obo:VO_0021168 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (XBB.1.5) 0.01 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0010747 a rdfs:Class ;
  rdfs:label "Varivax III vaccine" ;
  rdfs:comment "Trade Name: Varivax III" ;
  rdfs:subClassOf obo:VO_0000419 , obo:VO_0000455 , obo:VO_0000714 .

obo:VO_0002978 a rdfs:Class ;
  rdfs:label "Human Respiratory Syncytial Virus M2-2 mutant vaccine" ;
  rdfs:comment "An M2-2 mutant of human respiratory syncytial virus A2 is attenuated in African green monkeys. When challenged with wild type RSV, two doses provided complete protection against challenge in the lower respiratory tract and a significant reduction of the challenge virus in the upper respiratory tract" ;
  rdfs:subClassOf obo:VO_0002512 .

obo:VO_0020845 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Influsplit]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0020340 a rdfs:Class ;
  rdfs:label "Flulaval 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000043 , obo:VO_0010417 .

obo:VO_0001742 a rdfs:Class ;
  rdfs:label "Bordetella Bronchiseptica Avirulent Live Culture Vaccine (USDA: 1081.01)" ;
  rdfs:subClassOf obo:VO_0000394 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0001917 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Hardjo-Pomona Bacterin (USDA: 4399.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002351 .

obo:VO_0016220 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:VO_0002612 a rdfs:Class ;
  rdfs:label "aroA from Pasteurella multocida" ;
  rdfs:comment "An aroA mutant is highly attenuated in calves and induces significant protection from challenge with wild type P. multocida" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001418 .

obo:VO_0003929 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML [Fluad 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003913 .

obo:VO_0003323 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003212 .

obo:VO_0020552 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluarix] Box of 10" ;
  rdfs:subClassOf obo:VO_0020551 , obo:VO_0020603 , obo:VO_0020859 .

obo:VO_0016877 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016831 , obo:VO_0016837 .

obo:VO_0001703 a rdfs:Class ;
  rdfs:label "Mycoplasma Gallisepticum Live Culture Vaccine (USDA: 1751.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000949 , obo:VO_0001077 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0004184 a rdfs:Class ;
  rdfs:label "Salmonella IroN protein vaccine" ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0004589 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii DNA vaccine pDIP/PyCSPlasmodium 1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002514 .

obo:VO_0019252 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0016260 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 2 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0015920 .

obo:NCBITaxon_38568 a rdfs:Class ;
  rdfs:label "Leishmania <subgenus>" ;
  rdfs:subClassOf obo:NCBITaxon_5658 .

obo:VO_0001280 a rdfs:Class ;
  rdfs:label "obsolete immunization target role of pathogen" .

obo:VO_0011065 a rdfs:Class ;
  rdfs:label "TA4" ;
  rdfs:comment "The immunization procedure of DNA vaccine pcDNA-TA4-IL-2 of Eimeria tenella, including route, dose, time of immunization and age of primary immunization of chicken, was optimized.  results illustrated that 25 microg was the optimal dose and intramuscular injection was the most effective route to induce protective immunity in Chinese Yellow chickens [PubMed: 19019543]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010823 .

obo:VO_0019331 a rdfs:Class ;
  rdfs:label "0.5 ML measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML / mumps virus vaccine live, Jeryl Lynn strain 25000 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0020116 .

obo:VO_0015013 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0015014 .

obo:VO_0016665 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0016626 .

obo:VO_0002581 a rdfs:Class ;
  rdfs:label "obsolete aroC from Edwardsiella tarda" ;
  rdfs:comment "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" .

obo:VO_0019410 a rdfs:Class ;
  rdfs:label "Bacillus anthracis strain V770-NP1-R antigens Injectable Suspension [Biothrax]" ;
  rdfs:subClassOf obo:VO_0018596 .

obo:VO_0007374 a rdfs:Class ;
  rdfs:label "Dendritic Cell-targeting Lentiviral Vector ID-LV305 Vaccine" ;
  rdfs:comment "An engineered lentiviral vector targeting dendritic cells (DCs) and containing nucleic acids encoding for the human tumor-associated cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, the DC-targeting lentiviral vector ID-LV305 targets and binds to dermal DCs via the DC-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) receptor. Upon internalization of the vector, the NY-ESO-1 protein is expressed, stimulates DC maturation and activates the immune system to mount a cytotoxic T-lymphocyte (CTL) response against NY-ESO-1-expressing cells, which may result in tumor cell lysis. NY-ESO-1 is expressed in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005495 , obo:VO_0007657 .

obo:OPL_0000119 a rdfs:Class ;
  rdfs:label "exflagellated microgametocyte stage" ;
  rdfs:comment "A microgametocyte stage in some apicomplexan parasites where microgametocyte gets matured and form microgamete through the process known as exflagellation." ;
  rdfs:subClassOf obo:OPL_0000143 .

obo:VO_0005486 a rdfs:Class ;
  rdfs:label "lung cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against lung cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0001166 a rdfs:Class ;
  rdfs:label "intraperitoneal vaccination" ;
  rdfs:comment "a vaccination process that occurs in the intraperitoneal route" ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0004058 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis DNA vaccine encoding KatG" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:VO_0007099 a rdfs:Class ;
  rdfs:label "recombinant Fowlpox-gp100p209 vaccine" ;
  rdfs:comment "A melanoma vaccine comprised of a recombinant fowlpox vector construct encoding a modified epitope of the melanoma antigen glycoprotein 100 (gp100), ES-2092M(gp100), containing an endoplasmic reticulum signal sequence targeted to the endoplasmic reticulum apparatus. Vaccination with recombinant fowlpox-gp100p209 vaccine may stimulate the host immune system more efficiently to mount a cytotoxic T lymphocyte response against tumor cells expressing the gp100 antigen." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0015664 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015598 .

obo:VO_0010955 a rdfs:Class ;
  rdfs:label "CjaA from C. jejuni RM 1221" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010765 .

obo:VO_0015098 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Epaxal] Box of 10" ;
  rdfs:subClassOf obo:VO_0015095 , obo:VO_0015104 , obo:VO_0015255 .

obo:VO_0015568 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [H-B-Vax II]" ;
  rdfs:subClassOf obo:VO_0015490 , obo:VO_0015544 .

obo:VO_0000884 a rdfs:Class ;
  rdfs:label "aluminum vaccine adjuvant" ;
  rdfs:comment "A mineral salt vaccine adjuvant that is composed of some aluminum compound." ;
  rdfs:subClassOf obo:VO_0000093 .

obo:VO_0010029 a rdfs:Class ;
  rdfs:label "Leishmania  major LeIF" ;
  rdfs:comment "A LeIF protein that is part of Leishmania  major" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0017130 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [T Wellcovax]" ;
  rdfs:subClassOf obo:VO_0017129 , obo:VO_0017595 .

obo:VO_0002866 a rdfs:Class ;
  rdfs:label "obsolete Aro-deleted S. Typhi" ;
  rdfs:comment "Inactivation of AroD results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" .

obo:VO_0019804 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003589 , obo:VO_0019803 .

obo:VO_0007616 a rdfs:Class ;
  rdfs:label "HSPPC-96 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0021120 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.0857 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:VO_0002780 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis drrC mutant vaccine" ;
  rdfs:comment "A drrC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0017761 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 160 MG/ML [Tussoglobin]" ;
  rdfs:subClassOf obo:VO_0017760 .

obo:VO_0004855 a rdfs:Class ;
  rdfs:label "smallpox vaccine live vaccinia virus 500000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0004854 .

obo:VO_0018647 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003301 .

obo:VO_0005256 a rdfs:Class ;
  rdfs:label "HDT-301 vaccine" ;
  rdfs:comment "A SARS-CoV-2 Lipid-Inorganic Nanoparticle (LION(TM)) formulated replicating mRNA vaccine that encodes for a full-length spike (S) protein of the SARS-CoV-2 virus" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0003707 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003706 .

obo:VO_0016009 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015662 , obo:VO_0015800 .

obo:VO_0017203 a rdfs:Class ;
  rdfs:label "1 ML tetanus toxoid vaccine, inactivated 2000 IU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017530 .

obo:VO_0001775 a rdfs:Class ;
  rdfs:label "equine influenza live canarypox vector vaccine (USDA: 1501.R0)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0000484 , obo:VO_0001178 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0017410 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 , obo:VO_0018794 .

obo:VO_0004335 a rdfs:Class ;
  rdfs:label "Ebola virus recombinant rAD-GP encoding GP vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000726 .

obo:VO_0002970 a rdfs:Class ;
  rdfs:label "Herpes simplex virus 1 gD mutant vaccine" ;
  rdfs:comment "KOS-gDA3C is attenuated with mutations in gD gene in causing skin lesions at the inoculation and zosteriform sites, yet it is as effective as rKOS-gDA3C in protecting mice against HSV-1 challenge" ;
  rdfs:subClassOf obo:VO_0000958 .

obo:VO_0007221 a rdfs:Class ;
  rdfs:label "Allogeneic Dendritic Cell-Myeloma Idiotype Vaccine" ;
  rdfs:comment "A cell-based vaccine composed of allogeneic dendritic cells pulsed ex-vivo with an autologous myeloma idiotype with potential antineoplastic activity. Upon administration, allogeneic dendritic cell-myeloma idiotype vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against myeloma cells, resulting in cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0017059 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017049 , obo:VO_0017527 .

obo:VO_0016817 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0016732 , obo:VO_0016766 .

obo:VO_0016756 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Pediacel] Box of 20" ;
  rdfs:subClassOf obo:VO_0016716 , obo:VO_0016778 .

obo:VO_0018687 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML Oral Suspension" ;
  rdfs:subClassOf obo:VO_0018685 , obo:VO_0020187 .

obo:VO_0017183 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017626 .

obo:VO_0003081 a rdfs:Class ;
  rdfs:label "Trumenba vaccine" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000534 , obo:VO_0010292 , obo:VO_0010444 .

obo:VO_0000958 a rdfs:Class ;
  rdfs:label "Herpes simplex virus type 1 vaccine" ;
  rdfs:comment "A vaccine that protects against Herpes simplex virus type 1." ;
  rdfs:subClassOf obo:VO_0000727 .

obo:VO_0017464 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 1.5 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0000165 a rdfs:Class ;
  rdfs:label "bacterial vaccine" ;
  rdfs:comment "A vaccine that targets against a bacterial disease." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005504 .

obo:VO_0016936 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adt Vaccine]" ;
  rdfs:subClassOf obo:VO_0016933 , obo:VO_0017398 .

obo:VO_0016576 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Twinrix]" ;
  rdfs:subClassOf obo:VO_0000113 , obo:VO_0016580 .

obo:VO_0011419 a rdfs:Class ;
  rdfs:label "Mumps HN protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000656 .

obo:VO_0016155 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0019796 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003912 , obo:VO_0019795 .

obo:VO_0016882 a rdfs:Class ;
  rdfs:label "10 ML diphtheria toxoid vaccine, inactivated 0.5 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016834 , obo:VO_0016836 .

obo:VO_0003747 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003745 .

obo:VO_0011283 a rdfs:Class ;
  rdfs:label "LIPO-A" ;
  rdfs:comment "Study examined the immunogenic properties of the Leishmania infantum acidic ribosomal protein P0 (LiP0) in the BALB/c mouse model.  When mice were immunized with pcDNA3-LiP0, noticeable protection against L. major infection was achieved [PubMed: 14573678]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010836 .

obo:VO_0002903 a rdfs:Class ;
  rdfs:label "Salmonella Typhi phoP mutant vaccine" ;
  rdfs:comment "Three S. typhi deletion mutants (phoP, rpoS, and rpoS-phoP double mutant) were constructed and characterized with respect to invasiveness, virulence, and protective immune response compared with wild-type Ty2. All S. typhi mutants showed an increase in the specific serum IgG levels and T-cell-mediated immunity, and showed equal protection abilities against a wild-type Ty2 challenge after two rounds of immunization in BALB/c mice" ;
  rdfs:subClassOf obo:VO_0000671 .

obo:VO_0004676 a rdfs:Class ;
  rdfs:label "SL3261 expressing streptococcal M protein vaccine" ;
  rdfs:subClassOf obo:VO_0002852 .

obo:VO_0001276 a rdfs:Class ;
  rdfs:label "bacterial vaccine immunization" ;
  rdfs:subClassOf obo:VO_0000494 .

obo:VO_0003361 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010293 , obo:VO_0010444 .

obo:VO_0020059 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Injectable Suspension [Afluria 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020299 .

obo:VO_0001052 a rdfs:Class ;
  rdfs:label "poliovirus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a poliovirus strain" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0018183 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain Injectable Solution [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0018179 .

obo:VO_0000443 a rdfs:Class ;
  rdfs:label "vaccine effectiveness rate" ;
  rdfs:comment """A measurement datum that measues the vaccine effectiveness.  It is assessed with respect to prevention of the disease against which the vaccine is given. 
One simple method to estimate vaccine effectiveness is to use routine data on notifications of disease cases in vaccinated and unvaccinatted children and to compare the porportion of cases vaccinated with the vaccine covervage among the same age group in the general population. If p is the proportion vaccinated in the population and c is the proportion of cases reported to be vaccinated, then
VE = (p-c)/p(1-c) x 100%.""" ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0020109 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.04 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018797 .

obo:VO_0020516 a rdfs:Class ;
  rdfs:label "0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0020946 .

obo:VO_0021179 a rdfs:Class ;
  rdfs:label "0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Prefilled Syringe [Spikevax 2023-2024]" ;
  rdfs:subClassOf obo:VO_0021177 .

obo:VO_0017441 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.08 MG/ML [ActHIB]" ;
  rdfs:subClassOf obo:VO_0000004 , obo:VO_0017440 .

obo:VO_0000839 a rdfs:Class ;
  rdfs:label "Trovac AI H5 vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000461 , obo:VO_0003143 .

obo:VO_0011559 a rdfs:Class ;
  rdfs:label "Cervarix vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000556 , obo:VO_0000667 , obo:VO_0010446 .

obo:VO_0004641 a rdfs:Class ;
  rdfs:label "CAdVax-ZEBOV/SEBOV vaccine" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0001523 a rdfs:Class ;
  rdfs:label "Mannheimia haemolytica vaccine" ;
  rdfs:comment "Vaccine that protects against Mannheimia haemolytica infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0001041 a rdfs:Class ;
  rdfs:label "L. monocytogenes LM1-2 vaccine vector" ;
  rdfs:comment "A Listeria monocytogenes vaccine vector that uses the highly attenuated LM1-2 strain" ;
  rdfs:subClassOf obo:VO_0000068 .

obo:VO_0010281 a rdfs:Class ;
  rdfs:label "vaccination interval datum" ;
  rdfs:comment "A measurment datum that records the interval between vaccinations of a host." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0005043 a rdfs:Class ;
  rdfs:label "pCMN160 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCMN160.  This plasmid has a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000222 a rdfs:Class ;
  rdfs:label "pCMV-int DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007652 a rdfs:Class ;
  rdfs:label "alpha-GalCer-loaded tumor-cell vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0000066 a rdfs:Class ;
  rdfs:label "JE-Vax vaccine" ;
  rdfs:comment "JE-VAX is a sterile, lyophilized vaccine for subcutaneous use, prepared by inoculating mice intracerebrally with Japanese encephalitis (JE) virus, \"Nakayama-NIH\" strain." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000665 , obo:VO_0000712 , obo:VO_0000714 , obo:VO_0010440 .

obo:VO_0017890 a rdfs:Class ;
  rdfs:label "influenza B virus antigen, Hong Kong 330-2001 / meningococcal group C polysaccharide Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010444 , obo:VO_0017811 .

obo:VO_0011114 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Puerto Rico/8/1934(H1N1))" ;
  rdfs:comment "A recombinant baculovirus expressing the hemagglutinin gene of the influenza virus, A/PR/8/34 (H1N1), under the control of the chicken beta-actin promoter, was constructed.  Protection from a lethal challenge of the influenza virus was achieved by intranasal immunization of the recombinant baculovirus [PubMed: 12874198]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0006108 a rdfs:Class ;
  rdfs:label "nexavant vaccine adjuvant" ;
  rdfs:comment "A nucleic acid vaccine adjuvant that targets on TLR3 agonist to induce a mixed Th1/Th2 response." ;
  rdfs:subClassOf obo:VO_0006109 .

obo:VO_0020345 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2021-2022 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 , obo:VO_0010423 .

obo:OBI_0000011 a rdfs:Class ;
  rdfs:label "planned process"@en ;
  rdfs:comment "A process that realizes a plan which is the concretization of a plan specification."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0005267 a rdfs:Class ;
  rdfs:label "authorized COVID-19 recombinant vector vaccine" ;
  rdfs:subClassOf obo:VO_0005199 , obo:VO_0005264 .

obo:VO_0007217 a rdfs:Class ;
  rdfs:label "Allogeneic AML Antigen-expressing Dendritic Cell Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of allogeneic, immortalized dendritic precursor cells derived from a patient with acute myelogenous leukemia (AML), with potential immunostimulatory and antineoplastic activities. Upon ex vivo stimulation and expansion of the precursor cells into mature, fully functional dendritic cells (DCs) and subsequent administration, the allogeneic AML antigen-expressing DC vaccine may elicit a potent cytotoxic T-cell (CTL) and antibody response against AML antigen-expressing cells, resulting in tumor cell death." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005487 , obo:VO_0007657 .

obo:NCBITaxon_9900 a rdfs:Class ;
  rdfs:label "Bison" ;
  rdfs:subClassOf obo:NCBITaxon_27592 .

obo:VO_0019171 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0019466 .

obo:VO_0004602 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii recombinant vaccine vector rBCGpMV361-TgCyP" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000994 .

obo:VO_0010265 a rdfs:Class ;
  rdfs:label "host sex datum" ;
  rdfs:comment "A biological sex datum that records the biological sex of the target of a vaccine." ;
  rdfs:subClassOf obo:VO_0001194 .

obo:DOID_1498 a rdfs:Class ;
  rdfs:label "cholera"@en ;
  rdfs:comment "A primary bacterial infectious disease that is described as an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae, which is characterized by profuse watery diarrhea, vomiting, leg cramps, circulatory collapse and shock."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:VO_0015867 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 50" ;
  rdfs:subClassOf obo:VO_0015613 , obo:VO_0015689 , obo:VO_0015996 .

obo:VO_0000793 a rdfs:Class ;
  rdfs:label "Brucella abortus gene" ;
  rdfs:comment "A Brucella gene that is from B. abortus." ;
  rdfs:subClassOf obo:VO_0000790 .

obo:VO_0016232 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Mtk" ;
  rdfs:subClassOf obo:VO_0015906 .

obo:VO_0015927 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015633 , obo:VO_0015695 , obo:VO_0016032 .

obo:VO_0004068 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae GtS protein vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0001642 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.12)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0007347 a rdfs:Class ;
  rdfs:label "BC-819 vaccine" ;
  rdfs:comment "A cancer vaccine made with BC-819 (also known as DTA-H19), which is a double-stranded DNA plasmid, 4,560 base pairs (bp) in length, carrying the gene for the Diphtheria toxin A (DT-A) chain under the regulation of the H19 promoter. The DT-A chain expression is triggered by the presence of H19 transcription factors that are only up-regulated in tumor cells. The selective initiation of toxin expression results in selective tumor cell destruction via inhibition of protein synthesis selectively in the tumor cell, enabling highly targeted cancer treatment. It is used in combination with intravenously administered gemcitabine for patients with Locally Advanced Pancreatic Adenocarcinoma. The activation of the H19 gene promoter-containing plasmids and DTA expression are limited to tumor cells, as high levels of H19 expression are only found in tumor cells. DTA disrupts protein synthesis. Tumor-cell selective expression of this toxin leads to the selective destruction of the tumor while sparing healthy, normal cells." ;
  rdfs:subClassOf obo:VO_0005430 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0020734 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0020729 .

obo:OPL_0000306 a rdfs:Class ;
  rdfs:label "Plasmodium hepatic trophozoite stage" ;
  rdfs:comment "A hepatic trophozoite stage in the Plasmodium life cycle that occurs in hepatocytes of a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000261 , obo:OPL_0000303 .

obo:VO_0002137 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002395 , obo:VO_0007748 .

obo:VO_0019909 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluzone 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020482 .

obo:VO_0002841 a rdfs:Class ;
  rdfs:label "Francisella tularensis clpB mutant vaccine" ;
  rdfs:comment "A clpB mutant in Francisella tularensis subspecies tularensis strain SCHU S4 was attenuated and provided protection against aerosol challenge in mice" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0002713 a rdfs:Class ;
  rdfs:label "3c from Feline infectious peritonitis virus" ;
  rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001434 .

obo:VO_0001604 a rdfs:Class ;
  rdfs:label "Avian Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 10C5.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001527 , obo:VO_0007748 .

obo:VO_0004190 a rdfs:Class ;
  rdfs:label "Pseudomonas aeruginosa OprI protein vaccine" ;
  rdfs:subClassOf obo:VO_0000393 .

obo:VO_0018739 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 8 X" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010451 .

obo:VO_0015740 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015805 .

obo:VO_0018036 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0018033 .

obo:VO_0002702 a rdfs:Class ;
  rdfs:label "E(rns) from Classical swine fever virus" ;
  rdfs:comment "An N269A/Q mutation in the E(rns) protein created an attenuated mutant in swine. This mutant was able to induce effective protection in swine against challenge with wild type CSFV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001430 .

obo:VO_0015246 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015244 , obo:VO_0015245 .

obo:VO_0001904 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4145.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002346 .

obo:VO_0004199 a rdfs:Class ;
  rdfs:label "Leishmania amazonensis CP Protein vaccine" ;
  rdfs:subClassOf obo:VO_0012158 .

obo:VO_0003746 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003745 .

obo:VO_0019756 a rdfs:Class ;
  rdfs:label "influenza A virus A/Delaware/39/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Nebraska/14/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020333 .

obo:VO_0020362 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Extended Release Oral Capsule [Vivotif]" ;
  rdfs:subClassOf obo:VO_0003353 , obo:VO_0020371 .

obo:VO_0019923 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0002063 a rdfs:Class ;
  rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.F1)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002385 , obo:VO_0007748 .

obo:BFO_0000008 a rdfs:Class ;
  rdfs:label "temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:VO_0015127 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe [Epaxal]" ;
  rdfs:subClassOf obo:VO_0015126 , obo:VO_0015293 .

obo:VO_0019861 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0001583 a rdfs:Class ;
  rdfs:label "Trichomonas Foetus Killed Protozoa Vaccine (USDA: 1859.00)" ;
  rdfs:subClassOf obo:VO_0000315 , obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001457 .

obo:NCBITaxon_2946186 a rdfs:Class ;
  rdfs:label "Sedoreoviridae" ;
  rdfs:subClassOf obo:NCBITaxon_2732541 .

obo:VO_0020258 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 0.048 MG/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0000903 a rdfs:Class ;
  rdfs:label "secondary vaccination" ;
  rdfs:comment "Secondary vaccination is a vaccination that is performed immediately after the primary or the first vaccination." ;
  rdfs:subClassOf obo:VO_0000708 .

obo:VO_0018890 a rdfs:Class ;
  rdfs:label "influenza B virus B/Washington/02/2019 antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0010481 a rdfs:Class ;
  rdfs:label "licensed human leprosy vaccine" ;
  rdfs:comment "Leprosy vaccine that is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0006028 .

obo:VO_0015708 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 25" ;
  rdfs:subClassOf obo:VO_0015570 , obo:VO_0015791 .

obo:VO_0010702 a rdfs:Class ;
  rdfs:label "vaccine saftey regulation" ;
  rdfs:comment "A vaccine regulation for vaccine safety." ;
  rdfs:subClassOf obo:VO_0000683 .

obo:VO_0019539 a rdfs:Class ;
  rdfs:label "human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML / human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018797 .

obo:VO_0007569 a rdfs:Class ;
  rdfs:label "MAGE-A3/HPV 16 peptide vaccine" ;
  rdfs:comment "Gene name: MAGEA3" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0006066 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free pediatric 50 mcg/0.5 mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0004583 a rdfs:Class ;
  rdfs:label "Hirame rhabdovirus DNA vaccine encoding G" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002455 .

obo:VO_0003385 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:DOID_4953 a rdfs:Class ;
  rdfs:label "poliomyelitis"@en ;
  rdfs:comment "A viral infectious disease that results in destruction located in motor neurons, has_material_basis_in Human poliovirus 1, has_material_basis_in Human poliovirus 2, or has_material_basis_in Human poliovirus 3, which are transmitted by ingestion of food or water contaminated with feces, or transmitted by direct contact with the oral secretions. The infection has symptom fever, has symptom sore throat, has symptom headache, has symptom vomiting, has symptom fatigue, has symptom neck stiffness, has symptom muscle spasms, and has symptom acute flaccid paralysis."@en ;
  rdfs:subClassOf obo:DOID_574 , obo:DOID_934 .

obo:VO_0007150 a rdfs:Class ;
  rdfs:label "PSA RNA-Pulsed Dendritic Cell Vaccine" ;
  rdfs:comment "An autologous dendritic cell vaccine with potential immunostimulatory activity. Dendritic cells harvested from a prostate cancer patient are transfected with the mRNA encoding for prostate specific antigen (PSA), a tumor marker secreted by prostatic epithelial and ductal cells. When reintroduced back to the patient, these PSA RNA pulsed autologous dendritic cells may elicit a cytotoxic T-cell (CTL) response against PSA-positive prostate cancer cells." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0000313 a rdfs:Class ;
  rdfs:label "pSC65 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001599 a rdfs:Class ;
  rdfs:label "avian influenza H1N1 Subtype, Killed Virus Vaccine (USDA: 1057.H1)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0016700 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 30 UNT" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0010776 a rdfs:Class ;
  rdfs:label "Salmonella spp. protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:DOID_2531 a rdfs:Class ;
  rdfs:label "hematologic cancer"@en ;
  rdfs:comment "An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes."@en ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_74 .

obo:VO_0019393 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.08 MG/ML / diphtheria toxoid vaccine, inactivated 15 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017799 , obo:VO_0018770 .

obo:VO_0011146 a rdfs:Class ;
  rdfs:label "PrM from Japanese encephalitis virus" ;
  rdfs:comment "Researchers established a simple and effective method for DNA immunization against Japanese encephalitis virus (JEV) infection with plasmids encoding the viral PrM and E proteins and colloidal gold.   After being inoculated twice, BALB/c mice were found to resist challenge with 100,000 times the 50% lethal dose (LD(50)) of JEV (Beijing-1 strain) even when immunized with a relatively small dose of 0.5 micro g of plasmid DNA [PubMed: 12634382]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010783 .

obo:NCBITaxon_10366 a rdfs:Class ;
  rdfs:label "Murid betaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_10357 .

obo:VO_0012170 a rdfs:Class ;
  rdfs:label "Hendra virus vaccine" ;
  rdfs:comment "A vaccine that protects against Hendra virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0018474 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0018455 .

obo:VO_0001695 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 1 & 3, Live Virus Vaccine (USDA: 16L1.08)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0016748 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 20" ;
  rdfs:subClassOf obo:VO_0016712 , obo:VO_0016770 .

obo:OBI_0000426 a rdfs:Class ;
  rdfs:label "injection"@en ;
  rdfs:comment "injection is process which aims at introducing a compound or a mixture into a material entity (either biological entity or instrument) by relying on devices such as syringe or injector connection, attached or forced into a vascular system (veins of an organism or tubes of a machine) or in a tissue."@en ;
  rdfs:subClassOf obo:OBI_0000274 .

obo:VO_0002300 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.21)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002479 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0012159 a rdfs:Class ;
  rdfs:label "Leishmania infantum vaccine" ;
  rdfs:comment "A vaccine that protects against Leishmania infantum." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000762 .

obo:VO_0003372 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003371 .

obo:VO_0019155 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.006 MG/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000946 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0004119 a rdfs:Class ;
  rdfs:label "DNA vaccine encoding ANDV glycoproteins" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012167 .

obo:VO_0019995 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0003270 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injection [Heplisav-B]" ;
  rdfs:subClassOf obo:VO_0003965 .

obo:VO_0001869 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci-Rabies Modified Live Virus and Chlamydia, Canarypox Vector Vaccine (USDA: 1619.R1)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0001217 , obo:VO_0002438 , obo:VO_0007748 .

obo:VO_0004630 a rdfs:Class ;
  rdfs:label "AdC68- rabies virus glycoprotein vaccine" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0010298 a rdfs:Class ;
  rdfs:label "influenza A virus A/South Australia/55/2014 (H3N2) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003501 , obo:VO_0010299 .

obo:VO_0011290 a rdfs:Class ;
  rdfs:label "WD" ;
  rdfs:comment "DNA vaccination in BALB/c mice with the LAWD (for Leishmania antigenic WD protein) and IL-12 genes significantly delayed lesion development from challenge with Leishmania amazonensis, which correlated with a dramatic reduction in parasite burdens [PubMed: 15039343]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010837 .

obo:NCBITaxon_11520 a rdfs:Class ;
  rdfs:label "Influenza B virus" ;
  rdfs:subClassOf obo:NCBITaxon_197912 .

obo:VO_0001248 a rdfs:Class ;
  rdfs:label "Intanza vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000642 , obo:VO_0010415 .

obo:VO_0010060 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi PkAMA1" ;
  rdfs:comment "A PkAMA1 protein that is part of Plasmodium knowlesi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015472 .

obo:VO_0003892 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML [Flublok 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003890 .

obo:VO_0007595 a rdfs:Class ;
  rdfs:label "CpG 7909/PF3512676 vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0010966 a rdfs:Class ;
  rdfs:label "Omp25" ;
  rdfs:comment "Brucella Omp25 is a protective antigen [PubMed: 17049676]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0016739 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0016707 , obo:VO_0016773 .

obo:VO_0017289 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML / Bordetella pertussis 0.1 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017229 , obo:VO_0017288 .

obo:VO_0004485 a rdfs:Class ;
  rdfs:label "Vaccinia virus DNA vaccine 4pox" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000651 .

obo:VO_0005304 a rdfs:Class ;
  rdfs:label "TLR4 receptor role" ;
  rdfs:comment "A role of a material entity that binds to TLR4 and activates the receptor for pathogen recognition and activation of innate immunity." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0000726 a rdfs:Class ;
  rdfs:label "Ebola virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Ebola virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0005324 a rdfs:Class ;
  rdfs:label "Advax-CpG55.2 vaccine adjuvant" ;
  rdfs:comment "An Advax-CpG vaccine adjuvant that includes an inulin-based polysaccharide (Advax) and a CpG oligodeoxynucleotide CpG55.2." ;
  rdfs:subClassOf obo:VO_0005357 .

obo:VO_0001265 a rdfs:Class ;
  rdfs:label "AS04 vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant that is a combination of 50 ug of the immunoenhancer MPL (3-O-desacyl-4′-monophosphoryl lipid A) with 500 ug of aluminium salt." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0010302 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003498 , obo:VO_0010297 .

obo:VO_0001835 a rdfs:Class ;
  rdfs:label "Mink Distemper-Enteritis Modified Live & Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 4949.31)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0002450 , obo:VO_0007748 , obo:VO_0010475 .

obo:VO_0001391 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi PAR1 protein vaccine" ;
  rdfs:comment "A T. cruzi subunit vaccine that uses T. cruzi PAR1 protein as protective antigen." ;
  rdfs:subClassOf obo:VO_0001385 .

obo:VO_0020730 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Suspension [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020722 , obo:VO_0020729 , obo:VO_0020738 .

obo:VO_0016051 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 1" ;
  rdfs:subClassOf obo:VO_0003259 .

obo:VO_0019557 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flucelvax Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020331 .

obo:VO_0019938 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluzone Quadrivalent 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003611 .

obo:VO_0004209 a rdfs:Class ;
  rdfs:label "Ovine Ecthyma live virus vaccine by Colorado Serum Company CZ Veterinaria" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000503 , obo:VO_0001220 , obo:VO_0001460 .

obo:VO_0001943 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0018161 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 /ML" ;
  rdfs:subClassOf obo:VO_0015052 .

obo:VO_0002238 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza-West Nile Virus Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 46W5.21)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002423 , obo:VO_0003143 , obo:VO_0007748 .

obo:NCBITaxon_5875 a rdfs:Class ;
  rdfs:label "Theileria parva" ;
  rdfs:subClassOf obo:NCBITaxon_5873 .

obo:VO_0018314 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe [Rabipur] by Novartis" ;
  rdfs:subClassOf obo:VO_0018292 .

obo:VO_0015149 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix]" ;
  rdfs:subClassOf obo:VO_0015148 , obo:VO_0015238 .

obo:VO_0017731 a rdfs:Class ;
  rdfs:label "2 ML acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017762 .

obo:VO_0018869 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010325 , obo:VO_0010438 .

obo:OPL_0000278 a rdfs:Class ;
  rdfs:label "Plasmodium sporozoite" ;
  rdfs:comment "A Plasmodium that is formed in the oocyst and migrates to and reside in the salivary glands of the mosquito vector. A distinction is made between oocyst-derived and salivary gland-derived sporozoites. Sporozoites invade hepatocytes in the vertebrate host." ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0005238 a rdfs:Class ;
  rdfs:label "VBI-2902a vaccine" ;
  rdfs:comment "A SARS-CoV-2 virus-like particle vaccine that expresses a modified version of the SARS-CoV-2 spike (S) glycoprotein and is equipped with an aluminum phosphate adjuvant. It is manufactured by VBI Vaccines Inc. and is delivered intramuscularly." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005205 .

obo:VO_0000523 a rdfs:Class ;
  rdfs:label "smooth phenotype" ;
  rdfs:subClassOf obo:VO_0000549 .

obo:VO_0010783 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0000503 a rdfs:Class ;
  rdfs:label "licensed sheep vaccine" ;
  rdfs:subClassOf obo:VO_0000363 , obo:VO_0001476 .

obo:VO_0000015 a rdfs:Class ;
  rdfs:label "Boostrix vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000714 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0020522 a rdfs:Class ;
  rdfs:label "0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML Nasal Spray [Flumist] Box of 5 by Astrazeneca" ;
  rdfs:subClassOf obo:VO_0020521 .

obo:VO_0011157 a rdfs:Class ;
  rdfs:label "KMP-11" ;
  rdfs:comment "KMP-11 DNA vaccination alone in an experimental BALB/c mice model showed significant potential in terms of resolution of splenic and hepatic parasite burden against virulent LD challenge.  KMP-11 DNA immunization significantly protects against L. donovani infection [PubMed: 19162111]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0015275 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003431 .

obo:VO_0011480 a rdfs:Class ;
  rdfs:label "Human papillomavirus DNA vaccine pNGVL4a-E6/opt" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000667 .

obo:VO_0002791 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis proC mutant vaccine" ;
  rdfs:comment "A proC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis that is equal to the protection induced by the current vaccine BCG" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0017456 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis polysaccharide group Y tetanus toxoid conjugate 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0010436 , obo:VO_0017455 .

obo:VO_0001862 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 16E5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002437 , obo:VO_0007748 .

obo:VO_0020160 a rdfs:Class ;
  rdfs:label "Brucella melitensis as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0020589 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020588 .

obo:VO_0005319 a rdfs:Class ;
  rdfs:label "AZD2816 vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant vector vaccine by AstraZeneca and Oxford University against variant strain B.1.351" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0006026 a rdfs:Class ;
  rdfs:label "Japanese Encephalitis vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010440 .

obo:NCBITaxon_2560076 a rdfs:Class ;
  rdfs:label "Orthoparamyxovirinae" ;
  rdfs:subClassOf obo:NCBITaxon_11158 .

obo:VO_0015699 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015569 , obo:VO_0015788 .

obo:VO_0000411 a rdfs:Class ;
  rdfs:label "Brucella melitensis Bp26 and Tf protein vaccine" ;
  rdfs:subClassOf obo:VO_0001223 .

obo:VO_0007196 a rdfs:Class ;
  rdfs:label "obsolete Ad5-yCD/mutTKSR39rep-hIL12 Vaccine" .

obo:VO_0010175 a rdfs:Class ;
  rdfs:label "human papillomavirus 9-valent vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010446 .

obo:VO_0019576 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020489 .

obo:VO_0003070 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0019215 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0002966 a rdfs:Class ;
  rdfs:label "Gallid herpesvirus 1 UL0 mutant vaccine" ;
  rdfs:comment "A UL0 mutant in infectious laryngotracheitis virus (ILTV) was attenuated. Chickens immunized with UL0-negative ILTV were protected from clinical disease after subsequent infection with virulent ILTV" ;
  rdfs:subClassOf obo:VO_0001488 .

obo:VO_0002172 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Mass & Ark Types, Killed Virus Vaccine (USDA: 1785.12)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0003347 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0019137 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019136 , obo:VO_0020481 .

obo:VO_0011038 a rdfs:Class ;
  rdfs:label "PtxC" ;
  rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model.  These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:DOID_0050012 a rdfs:Class ;
  rdfs:label "chikungunya"@en ;
  rdfs:comment "A viral infectious disease that results_in infection located_in joint, has_material_basis_in Chikungunya virus (Alphavirus chikungunya), which is transmitted_by Aedes mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom maculopapular rash."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0004474 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine p1012D2ME encoding prM and E from DEN 2 New Guinea C strain" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0005296 a rdfs:Class ;
  rdfs:label "BECC470b vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0001827 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.22)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0002477 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0005499 a rdfs:Class ;
  rdfs:label "hepatocellular carcinoma vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against hepatocellular carcinoma." ;
  rdfs:subClassOf obo:VO_0000177 , obo:VO_0005429 .

obo:VO_0001735 a rdfs:Class ;
  rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001019 , obo:VO_0007748 .

obo:VO_0017409 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0017328 , obo:VO_0017408 .

obo:VO_0001302 a rdfs:Class ;
  rdfs:label "MTP-PE Liposomes vaccine adjuvant" ;
  rdfs:comment "A liposome-based vaccine adjuvant that consists of liposomes containing  the synthetic lipophilic analog of muramyl dipeptide, muramyl tripeptide phosphatidylethanolamine (MTP-PE)." ;
  rdfs:subClassOf obo:VO_0000366 .

obo:VO_0021002 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 UNT [Varivax]" ;
  rdfs:subClassOf obo:VO_0000119 , obo:VO_0021001 .

obo:VO_0010862 a rdfs:Class ;
  rdfs:label "VP30 from Reston ebolavirus" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0017190 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017189 , obo:VO_0017196 , obo:VO_0017633 .

obo:VO_0001275 a rdfs:Class ;
  rdfs:label "immunization target role" ;
  rdfs:comment "A role that represents a target (i.e., some disorder) of immunization." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0019409 a rdfs:Class ;
  rdfs:label "Bacillus anthracis strain V770-NP1-R antigens Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0010291 , obo:VO_0018595 .

obo:VO_0018434 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumopur]" ;
  rdfs:subClassOf obo:VO_0018424 .

obo:VO_0000395 a rdfs:Class ;
  rdfs:label "inactivated vaccine organism" ;
  rdfs:subClassOf obo:VO_0000506 .

obo:VO_0019472 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide / tetanus toxoid vaccine, inactivated Injectable Solution [OmniHIB]" ;
  rdfs:subClassOf obo:VO_0003121 , obo:VO_0019471 .

obo:VO_0001356 a rdfs:Class ;
  rdfs:label "particulate antigen delivery system vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that serves as a particulate antigen delivery system." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0010292 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0006059 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 10 mcg/0.2mL dose tris-sucrose formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0005332 a rdfs:Class ;
  rdfs:label "ARCT-165 vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by Arcturus Therapeutics, Inc., named as ARCT-165." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0001330 a rdfs:Class ;
  rdfs:label "AF03 vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant containing 2.5% squalene." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0017712 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017707 , obo:VO_0017759 .

obo:VO_0017337 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000742 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0010415 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0017799 .

obo:VO_0016683 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Diphtherie-Adsorbat-Impfstoff Behring]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0018240 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 20000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018254 .

obo:VO_0002661 a rdfs:Class ;
  rdfs:label "surA from Salmonella Typhimurium" ;
  rdfs:comment "A surA mutant (BRD1115) is attenuated in BALB/c mice and induces protection from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0018709 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 UNT Injectable Solution by Iaf Biovac" ;
  rdfs:subClassOf obo:VO_0018708 .

obo:VO_0011478 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis DNA vaccine APADNA priming and APAMVA boosting" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:VO_0019815 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003649 .

obo:VO_0017225 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017808 .

obo:VO_0002779 a rdfs:Class ;
  rdfs:label "Mycobacterium avium relA mutant vaccine" ;
  rdfs:comment "A M. avium relA mutant is attenuated in calves and goats. This mutant also elicited an immune response in goats that limited colonization by challenge wild type M. avium" ;
  rdfs:subClassOf obo:VO_0002501 .

obo:VO_0004748 a rdfs:Class ;
  rdfs:label "rPFV-CSFV-E0 vaccine" ;
  rdfs:subClassOf obo:VO_0001012 .

obo:NCBITaxon_10913 a rdfs:Class ;
  rdfs:label "Porcine rotavirus" ;
  rdfs:subClassOf obo:NCBITaxon_10912 .

obo:VO_0000582 a rdfs:Class ;
  rdfs:label "vaccine license application" ;
  rdfs:comment "A vaccine regulatory process that is for vaccine producer to apply for vaccine license." ;
  rdfs:subClassOf obo:VO_0000683 .

obo:VO_0007517 a rdfs:Class ;
  rdfs:label "dendritic cell/​myeloma fusion vaccine" ;
  rdfs:comment "A cancer vaccine onsisting of autologous dendritic cells (DCs) fused with patient-derived plasma cell (multiple) myeloma cells with potential immunostimulatory and antineoplastic activities. Autologous DC/multiple myeloma fusions stimulate both helper and cytotoxic T-lymphocyte (CTL) responses through the presentation of internalized and newly synthesized tumor associated antigens (TAAs). This may promote cellular and humoral antitumor immune responses in patients with plasma cell myeloma. This vaccine uses Dendritic cell/myeloma fusions with granulocyte macrophage colony-stimulating factor (GM-CSF) adjuvant plus lenalidomide maintenance therapy. The dendritic cell myeloma vaccine may improve response in patients with multiple myeloma after autologous Hematopoietic Cell Transplant (HCT)." ;
  rdfs:subClassOf obo:VO_0005492 , obo:VO_0007657 , obo:VO_0007658 .

obo:IAO_0000033 a rdfs:Class ;
  rdfs:label "directive information entity"@en ;
  rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0004260 a rdfs:Class ;
  rdfs:label "Hepatitis B surface antigen (HBsAg) with JVRS-1000 vaccine" ;
  rdfs:subClassOf obo:VO_0000644 .

obo:VO_0010932 a rdfs:Class ;
  rdfs:label "GP from Marburg Virus" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010769 .

obo:VO_0020329 a rdfs:Class ;
  rdfs:label "Flucelvax 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000980 , obo:VO_0010416 .

obo:VO_0016521 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by HVD" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0001196 a rdfs:Class ;
  rdfs:label "vaccination dose (unit: CFU)" ;
  rdfs:comment "A vaccination dose that is used with the unit of colony forming units (CFU)." ;
  rdfs:subClassOf obo:VO_0000814 .

obo:VO_0004084 a rdfs:Class ;
  rdfs:label "HC of type C and D vaccine" ;
  rdfs:subClassOf obo:VO_0012187 .

obo:VO_0003526 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Massachusetts-2-2012-like virus" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003520 , obo:VO_0010415 .

obo:VO_0018670 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 1000 MG Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0018668 , obo:VO_0018669 , obo:VO_0020188 .

obo:VO_0018907 a rdfs:Class ;
  rdfs:label "influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0003396 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine" ;
  rdfs:comment "A clostridium tetani vaccine that consists of formaldehyde inactivated tetanospasmin (aka tetanus toxoid)." ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000640 .

obo:VO_0001641 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0001536 a rdfs:Class ;
  rdfs:label "Mink Distemper Modified Live Virus Vaccine (USDA: 1451.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0007748 , obo:VO_0010475 , obo:VO_0012178 .

obo:VO_0000405 a rdfs:Class ;
  rdfs:label "AIDSVAX B/B vaccine" ;
  rdfs:comment "The AIDSVAX that is bicovalent vaccine including two kinds of gp120 protein: MN rgp120/HIV-1 and GNE8 rgp120/HIV-1 (MN and GNE8 are strain names)." ;
  rdfs:subClassOf obo:VO_0000402 , obo:VO_0000455 .

obo:VO_0001021 a rdfs:Class ;
  rdfs:label "live attenuated feline panleukopenia virus vaccine" ;
  rdfs:comment "a feline panleukopenia virus vaccine where the virus used is live attenuated. " ;
  rdfs:subClassOf obo:VO_0000389 , obo:VO_0001220 .

obo:VO_0015928 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 20" ;
  rdfs:subClassOf obo:VO_0015633 , obo:VO_0015696 , obo:VO_0016033 .

obo:VO_0001996 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:BFO_0000002 a rdfs:Class ;
  rdfs:label "continuant"@en ;
  rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:VO_0015527 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Intramuscular Solution [Recombivax]" ;
  rdfs:subClassOf obo:VO_0015521 , obo:VO_0015554 .

obo:VO_0010250 a rdfs:Class ;
  rdfs:label "host vaccination frequency variable" ;
  rdfs:comment "A variable representing the host vaccination frequency etc." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0020229 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010452 .

obo:VO_0019369 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.04 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0015498 .

obo:VO_0020497 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:NCBITaxon_2560069 a rdfs:Class ;
  rdfs:label "Avulavirinae" ;
  rdfs:subClassOf obo:NCBITaxon_11158 .

obo:NCBITaxon_162387 a rdfs:Class ;
  rdfs:label "Metapneumovirus" ;
  rdfs:subClassOf obo:NCBITaxon_11244 .

obo:VO_0015624 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B]" ;
  rdfs:subClassOf obo:VO_0003425 , obo:VO_0015545 .

obo:VO_0000709 a rdfs:Class ;
  rdfs:label "Brucella melitensis vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000025 .

obo:VO_0019626 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flulaval Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020344 .

obo:VO_0003645 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003639 .

obo:VO_0017304 a rdfs:Class ;
  rdfs:label "Bordetella pertussis / diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension [Tripacel]" ;
  rdfs:subClassOf obo:VO_0010742 , obo:VO_0017302 .

obo:VO_0011399 a rdfs:Class ;
  rdfs:label "Rift Valley Fever Virus DNA Vaccine encoding N Protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012166 .

obo:VO_0020628 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0020623 .

obo:NCBITaxon_11082 a rdfs:Class ;
  rdfs:label "West Nile virus" ;
  rdfs:subClassOf obo:NCBITaxon_3044782 .

obo:VO_0004990 a rdfs:Class ;
  rdfs:label "E protein of SARS-CoV-2" ;
  rdfs:subClassOf obo:VO_0004988 .

obo:VO_0002244 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 47E5.21)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001471 , obo:VO_0002387 , obo:VO_0007748 .

obo:VO_0004047 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus ClfA Protein vaccine" ;
  rdfs:subClassOf obo:VO_0002502 .

obo:VO_0020509 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0016929 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 2 LFU/ML / tetanus toxoid vaccine, inactivated 2 LFU/ML Injection" ;
  rdfs:subClassOf obo:VO_0017391 .

obo:VO_0011204 a rdfs:Class ;
  rdfs:label "PspA" ;
  rdfs:comment "Groups of BALB/c mice immunized with choline binding protein PspA were challenged with either D39 or WCH16. PspA elicited protection by using moderate challenge doses of S. pneumoniae [PubMed: 17088353]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0001891 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 4139.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002339 .

obo:VO_0001414 a rdfs:Class ;
  rdfs:label "Francisella tularensis gene" ;
  rdfs:comment "A bacterial gene that is from Francisella tularensis." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0016729 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac]" ;
  rdfs:subClassOf obo:VO_0016714 , obo:VO_0016734 .

obo:VO_0010016 a rdfs:Class ;
  rdfs:label "Leishmania  donovani Gp63" ;
  rdfs:comment "A Gp63 protein that is part of Leishmania  donovani" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0004278 a rdfs:Class ;
  rdfs:label "Tick-borne Encephalitis Virus C protein mutant vaccine" ;
  rdfs:subClassOf obo:VO_0012190 .

obo:VO_0004130 a rdfs:Class ;
  rdfs:label "Multivalent DNA vaccine for B. anthracis, Ebola virus, Marburg virus, and VEE virus" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012163 .

obo:OPL_0000075 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum macrogamete stage" ;
  rdfs:comment "A macrogamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000085 , obo:OPL_0000262 , obo:OPL_0000287 .

obo:VO_0004491 a rdfs:Class ;
  rdfs:label "Sindbis virus DNA vaccine encoding E2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003043 .

obo:VO_0011063 a rdfs:Class ;
  rdfs:label "MIC2" ;
  rdfs:comment "Birds vaccinated with Eimeria tenella microneme recombinant gene (EtMIC2) and encoded protein developed protective immunity against infection by E. tenella as assessed by significantly increased body weight gain and decreased fecal oocyst shedding compared with non-vaccinated controls. Vaccination with the EtMIC2 gene also led to protective immunity against infection by E. acervulina, but not E. maxima [PubMed: 15882535]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010823 .

obo:VO_0007358 a rdfs:Class ;
  rdfs:label "CD80 Breast Cancer Vaccine" ;
  rdfs:comment "A vaccine comprised of CD80-transfected allogenic breast cancer cells to induce T-cell response." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0010249 a rdfs:Class ;
  rdfs:label "pathogen attenuation variable" ;
  rdfs:comment "A variable representing the presence of an attenuation process (killed microbe) on a pathogen challenge" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:OBI_0000181 a rdfs:Class ;
  rdfs:label "population"@en ;
  rdfs:comment "a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0017310 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 4 LFU/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension [Adacel]" ;
  rdfs:subClassOf obo:VO_0017303 , obo:VO_0017309 .

obo:VO_0003065 a rdfs:Class ;
  rdfs:label "obsolete RB51 induced protection against B.Melitensis" .

obo:VO_0003713 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen" ;
  rdfs:comment "RXAUI: 9198756" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0017932 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0017900 .

obo:VO_0006018 a rdfs:Class ;
  rdfs:label "herpes simplex virus type 2 vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000727 .

obo:VO_0015688 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 3" ;
  rdfs:subClassOf obo:VO_0015565 , obo:VO_0015781 .

obo:VO_0011205 a rdfs:Class ;
  rdfs:label "NcDG2" ;
  rdfs:comment "Separate groups of gerbils were immunized with purified recombinant proteins singly or in combinations and animals were then challenged with N. caninum. The protective efficacy of each vaccination was determined by assessing animal survival rate.  All experimental groups showed protective effects.  Vaccination with NcDG2 alone elicited 50% survival rate compared to a control survival rate of 17.4% [PubMed: 15793355]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0019226 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2023 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020496 .

obo:DOID_8781 a rdfs:Class ;
  rdfs:label "rubella"@en ;
  rdfs:comment "A viral infectious disease that results_in infection located_in skin, has_material_basis_in Rubella virus (Rubivirus rubellae), which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection has_symptom rash on the face which spreads to the trunk and limbs, has_symptom fever, has_symptom lymphadenopathy, has_symptom joint pains, has_symptom headache, and has_symptom conjunctivitis."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0017384 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Adt Vaccine]" ;
  rdfs:subClassOf obo:VO_0017670 .

obo:VO_0017849 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine Injection [Meningitec]" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0010724 , obo:VO_0017900 .

obo:VO_0004822 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010449 .

obo:VO_0007432 a rdfs:Class ;
  rdfs:label "monoclonal antibody 105AD7 anti-idiotype vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a humanized monoclonal antibody that mimics a tumor-associated antigen 791Tgp72 (also known as CD55). Vaccination with this agent may stimulate a host cytotoxic T-cell response against tumor cells expressing CD55, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0005426 , obo:VO_0007657 .

obo:VO_0002672 a rdfs:Class ;
  rdfs:label "aroD from Shigella" ;
  rdfs:comment "An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000169 .

obo:VO_0007677 a rdfs:Class ;
  rdfs:label "hyperacute-prostate cancer vaccine" ;
  rdfs:comment "A cancer vaccine composed of irradiated allogeneic prostate cancer cell lines (HAP-1 and HAP-2) that have been transduced with a recombinant Moloney murine leukemia virus (MoMLV)-based retroviral vector expressing the murine alpha (1,3) GT gene, a mouse gene that causes the production of a foreign pattern of protein-sugars on the cell surface. It is hoped that the immune response to the foreign substance will stimulate the immune system to attack the patient's own cancer cells that have similar proteins without this sugar pattern, causing the tumor to remain stable or shrink.. The expression of the murine alpha (1,3) galactosyltransferase [alpha (1,3) GT] gene results in the cell surface expression of alpha (1,3) galactosyl-epitopes (alpha-gal) on membrane glycoproteins and glycolipids." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0015288 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML Injectable Solution [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015287 , obo:VO_0015289 .

obo:VO_0019618 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flublok Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020327 .

obo:NCBITaxon_67780 a rdfs:Class ;
  rdfs:label "Edwardsiella ictaluri" ;
  rdfs:subClassOf obo:NCBITaxon_635 .

obo:VO_0015747 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015812 .

obo:VO_0002852 a rdfs:Class ;
  rdfs:label "Streptococcus pyogenes vaccine" ;
  rdfs:comment "A Streptococcus  vaccine against Streptococcus pyogenes infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000772 .

obo:VO_0002471 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000639 , obo:VO_0000963 , obo:VO_0002474 .

obo:VO_0015788 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015491 .

obo:VO_0016863 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0016819 .

obo:VO_0000486 a rdfs:Class ;
  rdfs:label "chicken ovalbumin egg protein allergen" ;
  rdfs:comment "A chicken egg protein allergen where the protein allergen is ovalbumin, the main protein found in egg write, making up 60-65% of the total protein." ;
  rdfs:subClassOf obo:VO_0000912 .

obo:VO_0002691 a rdfs:Class ;
  rdfs:label "ipxM from Yersinia pestis" ;
  rdfs:comment "An IpxM mutant is attenuated in mice and guinea pigs. This mutant also conferred modest protection from challenge with wild type Y. pestis in Balb/c mice and significant protection in guinea pigs and outbred mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001426 .

obo:VO_0005357 a rdfs:Class ;
  rdfs:label "Advax-CpG vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that includes an inulin-based polysaccharide (Advax) and a CpG oligodeoxynucleotide (ODN)." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0000454 a rdfs:Class ;
  rdfs:label "APEC vaccine using GST-Iss fusion protein" ;
  rdfs:subClassOf obo:VO_0001156 .

obo:VO_0005003 a rdfs:Class ;
  rdfs:label "pHW2000 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pHW2000.  This plasmid is derived from pHW12 and contains part of the human pol I promoter and murine terminator sequences, a CMV promoter, and the polyadenylation signal of the gene encoding bovine growth hormone." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002646 a rdfs:Class ;
  rdfs:label "lppB from Salmonella Typhimurium" ;
  rdfs:comment "An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0019438 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.2 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0002418 a rdfs:Class ;
  rdfs:label "canine parainfluenza-bordetella bronchiseptica vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000394 , obo:VO_0000563 , obo:VO_0001471 , obo:VO_0001526 .

obo:VO_0015314 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injectable Solution [Vaqta]" ;
  rdfs:subClassOf obo:VO_0010745 , obo:VO_0015312 .

obo:VO_0015981 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Lt Grk] Box of 25" ;
  rdfs:subClassOf obo:VO_0015645 , obo:VO_0016059 .

obo:OPL_0000300 a rdfs:Class ;
  rdfs:label "Plasmodium sporozoite stage" ;
  rdfs:comment "A sporozoite stage in the Plasmodium lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000152 .

obo:VO_0004519 a rdfs:Class ;
  rdfs:label "Herpes Simplex Virus Type 1 DNA Vaccine pRSC-gD-IL-21" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0015087 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015245 .

obo:VO_0011264 a rdfs:Class ;
  rdfs:label "NP from Influenza A virus (A/nt/60/1968(H3N2))" ;
  rdfs:comment "Mice immunized with Recombinant-derived nucleoprotein (rNP) from S. typhimurium expressing the cloned NP gene from A/NT/60/68 (Jones & Brownlee, 1985) were protected against a lethal challenge with Influenza A/Puerto Rico/8/34 (A/PR8) virus but showed considerable morbidity before recovery [PubMed: 2172156]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0000970 a rdfs:Class ;
  rdfs:label "E. coli Tir protein vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0019976 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML [Fluvirin 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020473 .

obo:VO_0007088 a rdfs:Class ;
  rdfs:label "Viagenpumatucel-L Vaccine" ;
  rdfs:comment "A proprietary, allogeneic tumor cell vaccine expressing a recombinant secretory form of the heat shock protein gp96 fusion (gp96-Ig) with potential antineoplastic activity. Upon administration of viagenpumatucel-L, the irradiated live tumor cells continuously secrete gp96-Ig along with its chaperoned tumor associated antigens (TAAs) into the blood stream, thereby activating antigen presenting cells, natural killer cells and priming potent cytotoxic T lymphocytes (CTLs) to respond against TAAs on the endogenous tumor cells. Furthermore, this vaccine may induce long-lived memory T cells that could fight recurring cancer cells. gp96-Ig is constructed by replacing the KDEL retention sequence of gp96, normally an endoplasmatic reticulum-resident chaperone peptide, with the Fc portion of mouse and human IgG1." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0001345 a rdfs:Class ;
  rdfs:label "MPL-SE vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant containing MPL and squalene." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:OPL_0000187 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum ookinete stage" ;
  rdfs:comment "An ookinete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector and on the outside of the midgut." ;
  rdfs:subClassOf obo:OPL_0000153 , obo:OPL_0000165 , obo:OPL_0000296 .

obo:VO_0012404 a rdfs:Class ;
  rdfs:label "p60" ;
  rdfs:comment "Mice immunized with p60 encapsulated in  liposomes launched a strong CTL response and were protected against a subsequent challenge with L. monocytogenes [PubMed: 18433404]." ;
  rdfs:subClassOf obo:VO_0012369 .

obo:VO_0000764 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi vaccine" ;
  rdfs:comment "Vaccine that protects against Borrelia burgdorferi infection causing Lyme disease." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003518 .

obo:VO_0000946 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine" ;
  rdfs:comment "A vaccine that protects against, Diphtheria, Tetanus, Pertussis (whooping cough), Polio, Hepatitis B, and Haemophilus influenzae type b." ;
  rdfs:subClassOf obo:VO_0000744 , obo:VO_0000746 .

obo:VO_0015026 a rdfs:Class ;
  rdfs:label "Tenivac Injectable Product" ;
  rdfs:subClassOf obo:VO_0000102 .

obo:VO_0002125 a rdfs:Class ;
  rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002393 , obo:VO_0007748 .

obo:VO_0007120 a rdfs:Class ;
  rdfs:label "Vaccinia melanoma oncolysates (VMO) vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020634 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 PFU/ML Injectable Suspension [Zostavax]" ;
  rdfs:subClassOf obo:VO_0021027 .

obo:VO_0001838 a rdfs:Class ;
  rdfs:label "Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C Bacterin-Toxoid (USDA: 4955.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002451 , obo:VO_0007748 , obo:VO_0010475 .

obo:VO_0001032 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda EIB202 vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector using a live attenuated Edwardsiella tarda strain EIB202" ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0010049 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum PfSSP2" ;
  rdfs:comment "A PfSSP2 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0001689 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1641.06)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0004248 a rdfs:Class ;
  rdfs:label "recombinant NY-ESO-1 protein vaccine adjuvanted with imiquimod" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0019962 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Afluria 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019942 .

obo:VO_0015635 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0003422 , obo:VO_0015547 .

obo:VO_0000827 a rdfs:Class ;
  rdfs:label "AdsecV vaccine" ;
  rdfs:comment "A Yersinia pestis vaccine that uses a recombinant Ad5-based vector (E1a, partial E1b, and partial E3 deletion) to express Y. pestis V antigen." ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0021149 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.12 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 31 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 33 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 45 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 52 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 58 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.06 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 .

obo:VO_0010034 a rdfs:Class ;
  rdfs:label "Neospora caninum MIC10" ;
  rdfs:comment "A MIC10 protein that is part of Neospora caninum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0010180 a rdfs:Class ;
  rdfs:label "influenza, split virus, trivalent, injectable, contains preservative" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0018290 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur]" ;
  rdfs:subClassOf obo:VO_0018276 , obo:VO_0018295 .

obo:VO_0001525 a rdfs:Class ;
  rdfs:label "Duck enteritis virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Duck enteritis virus (Anatid herpesvirus 1) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000727 , obo:VO_0001469 .

obo:VO_0020306 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2022-2023 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0001817 , obo:VO_0010428 .

obo:VO_0003735 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML [Afluria 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003733 .

obo:VO_0003346 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0002156 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Conn Type, Live Virus Vaccine (USDA: 1761.1A)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0011070 a rdfs:Class ;
  rdfs:label "FopB" ;
  rdfs:comment "Intranasal immunization of HLA-DR4 tg mice with the single antigen FopB from F. tularensis subsp. novicida conferred significant protection against lethal pulmonary challenge with an F. tularensis subsp. holarctica live vaccine strain." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:VO_0001128 a rdfs:Class ;
  rdfs:label "ALVAC vaccine vector" ;
  rdfs:comment "a canarypox vaccine vector that uses an attenuated canarypox virus strain ALVAC. The ALVAC vector is a canarypox virus clone obtained after four rounds of plaque purification of a strain from a vaccine for canaries. " ;
  rdfs:subClassOf obo:VO_0001043 .

obo:VO_0020189 a rdfs:Class ;
  rdfs:label "rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML [Meruvax II]" ;
  rdfs:subClassOf obo:VO_0000073 , obo:VO_0015055 .

obo:VO_0007232 a rdfs:Class ;
  rdfs:label "Allogeneic Renal Cell Carcinoma Vaccine MGN1601" ;
  rdfs:comment "A whole cell vaccine comprised of irradiated allogeneic renal cell carcinoma (RCC) with potential immunostimulating and antineoplastic activities. Allogeneic renal cell carcinoma vaccine MGN1601 contains two active ingredients: 1) genetically modified allogeneic RCC cells that are transiently transfected with four different MIDGE (Minimalistic Immunogenically Defined Gene Expression) vectors encoding IL-7, GM-CSF, CD80 and CD154 and 2) the synthetic DNA-based immunomodulator dSLIM-30L1, a TLR9 agonist.. Vaccination results in expression of IL-7, GM-CSF, CD80 and CD154, which all contribute to the activation or enhancement of immune responses. Furthermore, administration of this RCC vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor growth. TLR9 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0000182 a rdfs:Class ;
  rdfs:label "vaccine-induced antibacterial agglutination antibody response" ;
  rdfs:subClassOf obo:VO_0000632 .

obo:VO_0015675 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015561 , obo:VO_0015769 .

obo:VO_0001200 a rdfs:Class ;
  rdfs:label "Leishmune vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000649 , obo:VO_0001142 .

obo:VO_0002284 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002431 , obo:VO_0007748 .

obo:VO_0002678 a rdfs:Class ;
  rdfs:label "senA from Shigella" ;
  rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000169 .

obo:VO_0015777 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015595 .

obo:VO_0020385 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 1000000000 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020370 , obo:VO_0020374 .

obo:VO_0016536 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0015270 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0015268 , obo:VO_0015273 .

obo:VO_0003414 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML Injection [PedvaxHIB]" ;
  rdfs:subClassOf obo:VO_0003412 .

obo:NCBITaxon_976 a rdfs:Class ;
  rdfs:label "Bacteroidota" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:VO_0010096 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA25" ;
  rdfs:comment "A GRA25 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:DOID_5517 a rdfs:Class ;
  rdfs:label "stomach carcinoma"@en ;
  rdfs:comment "A stomach cancer that is located_in the stomach."@en ;
  rdfs:subClassOf obo:DOID_10534 , obo:DOID_305 .

obo:VO_0018598 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 770000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004825 .

obo:VO_0011507 a rdfs:Class ;
  rdfs:label "Cancer Subunit GV1001 Protein Vaccine" ;
  rdfs:comment "Gene name: TERT" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0002052 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Standard & Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C8.42)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0004445 a rdfs:Class ;
  rdfs:label "Prostate cancer DNA vaccine pcDNA3-STEAP encoding six-transmembrane epithelial antigen" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0001062 a rdfs:Class ;
  rdfs:label "myxoma virus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a myxoma virus strain" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0017144 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017143 .

obo:VO_0015053 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0015052 .

obo:VO_0010921 a rdfs:Class ;
  rdfs:label "LolC/E" ;
  rdfs:comment "LolC was evaluated as an antigen for a vaccine candidate against B. pseudomallei infection. Nonmembrane regions of the B. pseudomallei protein was expressed and purified from Escherichia coli and then evaluated as a vaccine candidate in an established mouse model of B. pseudomallei infection. When delivered with the monophosphoryl lipid A-trehalose dicorynomycolate adjuvant, the protein stimulated antigen-specific humoral and cellular immune responses. Immunization with the LolC protein domain afforded significant protection against a subsequent challenge with B. pseudomallei.  LolC provided a greater level of protection when it was administered with immune-stimulating complexes complexed with CpG oligodeoxynucleotide 10103. Immunization with LolC also protected against a subsequent challenge with a heterologous strain of B. pseudomallei, demonstrating the potential utility of this protein as a vaccine antigen for melioidosis [PubMed: 17517877]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010840 .

obo:VO_0019204 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [FluLaval Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003763 , obo:VO_0010427 .

obo:VO_0020746 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 120 MG Injectable Solution [Pacis] by ID bio" ;
  rdfs:subClassOf obo:VO_0020745 .

obo:VO_0016871 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] Box of 50 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016811 .

obo:VO_0007421 a rdfs:Class ;
  rdfs:label "MUC1 antigen/SB AS-2 vaccine" ;
  rdfs:comment "Gene name: MUC1" ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0000362 a rdfs:Class ;
  rdfs:label "USA licensed human vaccine" ;
  rdfs:comment "a licensed human vaccine that is licensed in the USA." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000635 , obo:VO_0001485 .

obo:VO_0001403 a rdfs:Class ;
  rdfs:label "Listeria monocytogenes gene" ;
  rdfs:comment "A bacterial gene that is from Listeria monocytogenes." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0002627 a rdfs:Class ;
  rdfs:label "cpxR from Salmonella Gallinarum" ;
  rdfs:comment "A cpxR mutant, in combination with a lon mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001420 .

obo:VO_0020912 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain Injectable Suspension [Intanza]" ;
  rdfs:subClassOf obo:VO_0001248 , obo:VO_0020911 .

obo:VO_0003786 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003784 .

obo:VO_0001008 a rdfs:Class ;
  rdfs:label "Giardiavax vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000649 , obo:VO_0001083 .

obo:VO_0017076 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017075 .

obo:VO_0001446 a rdfs:Class ;
  rdfs:label "Tick-borne Encephalitis Virus gene" ;
  rdfs:comment "A viral gene that is from Tick-borne Encephalitis Virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0016271 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015923 .

obo:VO_0021174 a rdfs:Class ;
  rdfs:label "0.3 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (XBB.1.5) 0.1 MG/ML Injection [Comirnaty 2023-2024]" ;
  rdfs:subClassOf obo:VO_0021172 .

obo:VO_0015337 a rdfs:Class ;
  rdfs:label "Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0000950 , obo:VO_0001214 .

obo:VO_0000723 a rdfs:Class ;
  rdfs:label "Brucella abortus strain 45/20 vaccine" ;
  rdfs:subClassOf obo:VO_0001134 , obo:VO_0001466 , obo:VO_0001476 .

obo:NCBITaxon_11286 a rdfs:Class ;
  rdfs:label "Lyssavirus" ;
  rdfs:subClassOf obo:NCBITaxon_11270 .

obo:VO_0007395 a rdfs:Class ;
  rdfs:label "Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine" ;
  rdfs:comment "A multivalent vaccine againt breast cancer that comprised of the epitope antigens of Globo H hexasaccharide 1 (Globo H), GM2 ganglioside, Lewis-Y, MUC1-32(aa), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin, with potential antineoplastic activity. The antigens included in this vaccine are associated various cancer cells. Vaccination with this multivalent vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0002746 a rdfs:Class ;
  rdfs:label "E1 glycoprotein from VEE Virus" ;
  rdfs:comment "A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001447 .

obo:NCBITaxon_197912 a rdfs:Class ;
  rdfs:label "Betainfluenzavirus" ;
  rdfs:subClassOf obo:NCBITaxon_11308 .

obo:VO_0005044 a rdfs:Class ;
  rdfs:label "V1Jns DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label V1Jns.  This plasmid contains the human CMV promoter, enhancer and intron A as well as the polyadenylation sequences of bovine growth hormone." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0005227 a rdfs:Class ;
  rdfs:label "BBV154 vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant adenoviral vector vaccine that is manufactured by Bharat Biotech International Ltd. and administered intranasally" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:VO_0004377 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine pTS encoding Trypanosoma cruzi antigens" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0020269 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003401 .

obo:VO_0003273 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000419 , obo:VO_0000455 .

obo:VO_0017224 a rdfs:Class ;
  rdfs:label "7.5 ML tetanus toxoid vaccine, inactivated 5.33 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017223 , obo:VO_0017584 .

obo:VO_0011500 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus DNA vaccine encoding NS1 (pUSK-NS1)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000665 .

obo:VO_0018247 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus 1000 UNT / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2000 PFU" ;
  rdfs:subClassOf obo:VO_0000737 .

obo:VO_0005098 a rdfs:Class ;
  rdfs:label "V591 vaccine" ;
  rdfs:comment "A SARS-CoV-2 vaccine candidate that uses a measles virus vector platform, and is made by Merck. Development of the vaccine was discontinued on January 25, 2021." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005267 .

obo:VO_0007355 a rdfs:Class ;
  rdfs:label "Bcr-Abl (b2a2)-derived peptide vaccine" ;
  rdfs:comment "A cancer vaccine consisting of the bcr-abl b2a2 fusion oncoprotein, frequently expressed in chronic myelogenous leukemia (CML), with potential antineoplastic activity. Vaccination with the bcr-abl (b2a2)-derived peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express the bcr-abl b2a2 fusion protein. (NCIT_C61309) The vaccine is made from made from the proteins that cause leukemia cells in CML to behave abnormally. Imatinib mesylate is the standard therapy for CML and blocks the function of this protein. In combination, these may decrease or eliminate all evidence of disease in patients who have CML that is in remission after treatment with imatinib mesylate, but who still have small amounts of detectable disease." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0001637 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0011258 a rdfs:Class ;
  rdfs:label "VP6 from Bovine rotavirus" ;
  rdfs:comment "Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system.  Challenge of neonates born to animals immunized with VP6 protein showed partial protection [PubMed: 8382422]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010789 .

obo:VO_0020071 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0018601 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 980000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004823 .

obo:VO_0019356 a rdfs:Class ;
  rdfs:label "0.7 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020495 .

obo:VO_0005419 a rdfs:Class ;
  rdfs:label "MicroCrystalline Tyrosine vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002018 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 4570.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0000974 , obo:VO_0002375 .

obo:VO_0017065 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017061 , obo:VO_0017542 .

obo:VO_0018873 a rdfs:Class ;
  rdfs:label "influenza A virus (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:VO_0007641 a rdfs:Class ;
  rdfs:label "Melan-A/Mart-1 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0005272 a rdfs:Class ;
  rdfs:label "TLR7 receptor role" ;
  rdfs:comment "A role of a material entity that binds to TLR7 and activates the receptor for pathogen recognition and activation of innate immunity." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:NCBITaxon_40051 a rdfs:Class ;
  rdfs:label "Bluetongue virus" ;
  rdfs:subClassOf obo:NCBITaxon_10892 .

obo:VO_0001594 a rdfs:Class ;
  rdfs:label "avian influenza H5N9 Subtype, Killed Virus Vaccine (USDA: 1057.14)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:NCBITaxon_12814 a rdfs:Class ;
  rdfs:label "Respiratory syncytial virus" ;
  rdfs:subClassOf obo:NCBITaxon_11246 .

obo:NCBITaxon_11978 a rdfs:Class ;
  rdfs:label "Feline calicivirus" ;
  rdfs:subClassOf obo:NCBITaxon_11974 .

obo:VO_0019763 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:NCBITaxon_747 a rdfs:Class ;
  rdfs:label "Pasteurella multocida" ;
  rdfs:subClassOf obo:NCBITaxon_712 .

obo:VO_0015326 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Intramuscular Solution [Vivaxim]" ;
  rdfs:subClassOf obo:VO_0010748 , obo:VO_0015325 .

obo:VO_0019692 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Afluria 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003721 , obo:VO_0019691 .

obo:VO_0005140 a rdfs:Class ;
  rdfs:label "MVvac2-MERS-solS vaccine" ;
  rdfs:comment "A MERS recombinant vector made of MVvac2 (measle virus) expressing a soluble, truncated version of spike glycoprotein of MERS-CoV in its full length cloned into the MVvac2 genome and rescued." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0001999 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.01)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:VO_0018925 a rdfs:Class ;
  rdfs:label "influenza A virus A/Victoria/2570/2019 (H1N1) antigen" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0000009 a rdfs:Class ;
  rdfs:label "vaccine-induced B cell antigen processing and presentation" ;
  rdfs:subClassOf obo:VO_0000012 .

obo:VO_0019850 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:VO_0018789 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.03 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000195 , obo:VO_0000508 , obo:VO_0001214 .

obo:VO_0018698 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain Powder for Oral Suspension" ;
  rdfs:subClassOf obo:VO_0004815 .

obo:VO_0005805 a rdfs:Class ;
  rdfs:label "Giardia lamblia vaccine using attenuated Salmonella vaccine expressing VSPH7" ;
  rdfs:comment "A Live attenuated vaccine expressing VSPH7 that immunizes against Giardi lamblia trophozoite." ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0001083 .

obo:VO_0016856 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Revaxis] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016804 .

obo:VO_0019573 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003627 , obo:VO_0019544 .

obo:VO_0010854 a rdfs:Class ;
  rdfs:label "Trypanosoma brucei protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0002114 a rdfs:Class ;
  rdfs:label "Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002417 , obo:VO_0007748 .

obo:VO_0010201 a rdfs:Class ;
  rdfs:label "meningococcal polysaccharide vaccine (MPSV4)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0019637 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020495 .

obo:VO_0016924 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / pertactin adsorbed 0.005 MG/ML / Pertussis Vaccine 0.016 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0016923 , obo:VO_0017313 .

obo:VO_0019882 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0017489 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:VO_0001475 a rdfs:Class ;
  rdfs:label "sei whale vaccine" ;
  rdfs:comment "Vaccine that used for immunizing sei whale." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001218 .

obo:VO_0017550 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML [Covaxis]" ;
  rdfs:subClassOf obo:VO_0017548 .

obo:VO_0019731 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/11/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Delaware/55/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML / influenza B virus B/Singapore/WUH4618/2021 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0016961 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016956 .

obo:VO_0018307 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT Injection" ;
  rdfs:subClassOf obo:VO_0018269 , obo:VO_0020180 .

obo:VO_0016737 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0016707 , obo:VO_0016770 .

obo:VO_0005283 a rdfs:Class ;
  rdfs:label "TQL-1055 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0018289 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003858 , obo:VO_0018275 .

obo:NCBITaxon_10150 a rdfs:Class ;
  rdfs:label "Chinchillidae" ;
  rdfs:subClassOf obo:NCBITaxon_33550 .

obo:VO_0003156 a rdfs:Class ;
  rdfs:label "HPV-16 L1 VLP vaccine" ;
  rdfs:comment "A human paillomavirus vaccine that has the vaccine antigen ingredient of monovalent non-infectious, L1 recombinant HPV-like particles (VLP)." ;
  rdfs:subClassOf obo:VO_0000667 .

obo:VO_0020651 a rdfs:Class ;
  rdfs:label "1 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution [Varilrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0020647 , obo:VO_0021016 .

obo:VO_0007388 a rdfs:Class ;
  rdfs:label "HLA-A2-Restricted Synthetic Glioma Antigen Peptides Vaccine" ;
  rdfs:comment "Gene name: SOX6" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0004559 a rdfs:Class ;
  rdfs:label "Helicobacter pylori DNA vaccine poipA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012181 .

obo:VO_0016652 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by HVD" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0001233 a rdfs:Class ;
  rdfs:label "viral vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a viral vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0016459 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Mtk" ;
  rdfs:subClassOf obo:VO_0015975 .

obo:VO_0004572 a rdfs:Class ;
  rdfs:label "Pseudomonas aeruginosa DNA vaccine pGACAG-OprF/OprI + pGACAG-PcrV + pGACAG-PilA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000393 .

obo:VO_0002689 a rdfs:Class ;
  rdfs:label "guaA from Yersinia pestis" ;
  rdfs:comment "A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001426 .

obo:VO_0011425 a rdfs:Class ;
  rdfs:label "Chlamydophila pneumoniae DNA vaccine encoding Ssb" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012173 .

obo:VO_0011333 a rdfs:Class ;
  rdfs:label "Pra" ;
  rdfs:comment "C57BL6 mice were immunized with syngeneic, bone marrow-derived DCs (JAWS II cells) transfected with a cDNA encoding the protective Coccidioides-Ag2/proline-rich Ag (pra). The immunized mice were lethally challenged with C. posadasii through either an i.p. or intranasal route. Upon necropsy after 10 days of infection, fungal burden in lung and spleen of immunized mice was significantly reduced as compared with the control animals. The lung tissue homogenates of immunized animals showed higher levels of IFN-gamma. Histologically, lung tissues of immunized mice were in better condition than the control mice [PubMed: 16148136]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010853 .

obo:VO_0001175 a rdfs:Class ;
  rdfs:label "Brucella abortus L7/L12 fused to MBP vaccine" ;
  rdfs:comment "B. abortus L7/L12 fused to MBP is a B. abortus subunit vaccine using L7/L12 that uses recombinant L7/L12 fused on maltose binding protein MBP." ;
  rdfs:subClassOf obo:VO_0000323 .

obo:VO_0003860 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML [Imovax]" ;
  rdfs:subClassOf obo:VO_0000063 .

obo:VO_0000048 a rdfs:Class ;
  rdfs:label "virmugen" ;
  rdfs:comment "A gene that once deleted, would make an attenuated microbe that can be used as a live attenuated vaccine against virulent pathogen." ;
  rdfs:subClassOf obo:OGG_0000000002 .

obo:VO_0001919 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4389.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002352 .

obo:VO_0016278 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Mtk" ;
  rdfs:subClassOf obo:VO_0015924 .

obo:VO_0004914 a rdfs:Class ;
  rdfs:label "virus-like particle vaccine" ;
  rdfs:comment "A vaccine that uses virus-like particles (VLPs), multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccines." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:VO_0000374 a rdfs:Class ;
  rdfs:label "divalent DNA Brucella abortus vaccine using L7/L12 and Omp16" ;
  rdfs:subClassOf obo:VO_0001225 .

obo:VO_0020950 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0020941 .

obo:VO_0015226 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015224 .

obo:VO_0000734 a rdfs:Class ;
  rdfs:label "CVD 1204(pGA1-CS3) vaccine" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0002381 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Vaccine-Leptospira Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0001466 , obo:VO_0001501 .

obo:VO_0004453 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine pMIC3i encoding the complete MIC3-ORF (RH(ERP) strain)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:OPL_0000288 a rdfs:Class ;
  rdfs:label "Plasmodium microgamete stage" ;
  rdfs:comment "A microgamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000026 , obo:OPL_0000286 .

obo:VO_0016547 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by MSD" ;
  rdfs:subClassOf obo:VO_0015984 .

obo:VO_0003926 a rdfs:Class ;
  rdfs:label "Fluad 2017-2018 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003924 .

obo:VO_0015878 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015617 , obo:VO_0016003 .

obo:VO_0020381 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Prefilled Syringe [Typherix]" ;
  rdfs:subClassOf obo:VO_0010744 , obo:VO_0020280 .

obo:VO_0000786 a rdfs:Class ;
  rdfs:label "DNA and adenoviral vector Ad5 expressing SIV gag protein vaccine" ;
  rdfs:comment "A vaccine combination that includes a DNA vaccine and a recombinant adenovirus Ad5 expressing the same codon-optimized SIV gag gene. The DNA vaccine is used for priming, and the Ad5 vaccine is used for boosting. PMID:11797011." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0001038 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae HS93Tox vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector using the HS93Tox- mutant of the serovar 7 strain of Actinobacillus pleuropneumoniae. This mutant lacks the genes encoding the toxin ApxA and the post-translational activating protein ApxC, but still has genes required for secretion, making it a good vector." ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0020741 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain Injection [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020740 .

obo:VO_0018445 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumopur] Box of 10" ;
  rdfs:subClassOf obo:VO_0018424 .

obo:VO_0002955 a rdfs:Class ;
  rdfs:label "Equid herpesvirus gE mutant vaccine" ;
  rdfs:comment "A glycoprotein E mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice" ;
  rdfs:subClassOf obo:VO_0001486 .

obo:VO_0003256 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0001211 a rdfs:Class ;
  rdfs:label "African swine fever virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against African swine fever virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0004379 a rdfs:Class ;
  rdfs:label "Lassa fever virus recombinant vector vaccine V-LSG/N encoding the glycoprotein and the nucleoprotein" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012177 .

obo:VO_0001708 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 17A2.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0000481 a rdfs:Class ;
  rdfs:label "E. coli subunit vaccine using IroN" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0000099 a rdfs:Class ;
  rdfs:label "Pcaggs DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007699 a rdfs:Class ;
  rdfs:label "multi-epitope HER2 peptide vaccine TPIV100" ;
  rdfs:comment "A cancer vaccine comprised of four peptides derived from the tumor-associated antigen (TAA) HER-2/neu (ErbB-2), with potential immunomodulating and antineoplastic activities. The four peptides may induce a cytotoxic T-lymphocyte (CTL)-mediated immune response against tumor cells expressing the HER-2/neu antigen, which may result in the inhibition of proliferation in Her-2/neu-expressing tumor cells. TPIV100 is a type of vaccine made from HER2 peptide that may help the body build an effective immune response to kill tumor cells that express HER2. Sargramostim increases the number of white blood cells in the body following chemotherapy for certain types of cancer and is used to alert the immune system. TPIV100 and sargramostim could work in treating patients with HER2 positive, stage II-III breast cancer." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0018619 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML [Jespect]" ;
  rdfs:subClassOf obo:VO_0018799 .

obo:VO_0019604 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020305 .

obo:VO_0017518 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 2 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0000201 a rdfs:Class ;
  rdfs:label "Porcilis-PCV2 vaccine" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001524 .

obo:VO_0010832 a rdfs:Class ;
  rdfs:label "Leishmania donovani protein" ;
  rdfs:subClassOf obo:VO_0015478 .

obo:VO_0021005 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 UNT Injection [Varivax]" ;
  rdfs:subClassOf obo:VO_0021002 , obo:VO_0021004 .

obo:VO_0001701 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 16L1.07)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0001310 a rdfs:Class ;
  rdfs:label "QS-21 vaccine adjuvant" ;
  rdfs:comment "A saponin vaccine adjuvant that is composed of extracts from the bark of the Quillaja saponaria Molina tree. Specifically, it is an acylated 3, 28-bisdesmodic triterpene glycosides (1,3) or \"saponin\"  with a molecular formula of C92O46H148 and molecular weight of 1990 Da. QS-21 is one of the active fractions of the bark of Chilean tree, Quillaja saponaria, purified using a reverse-phase chromatography (RP-HPLC)." ;
  rdfs:subClassOf obo:VO_0001267 .

obo:VO_0010100 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA8" ;
  rdfs:comment "A GRA8 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0002208 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002412 , obo:VO_0007748 .

obo:VO_0017155 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix] Box of 25 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017154 .

obo:VO_0006037 a rdfs:Class ;
  rdfs:label "Novel influenza-H1N1-09 all formulations" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0010415 .

obo:OPL_0000245 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum erythrocytic merozoite stage" ;
  rdfs:comment "An erythrocytic merozoite stage in the Plasmodium falciparum lifecycle that occurs in the bloodstream of a human host." ;
  rdfs:subClassOf obo:OPL_0000103 , obo:OPL_0000248 , obo:OPL_0000293 .

obo:VO_0015015 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0015016 .

obo:VO_0019723 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0019190 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0000170 a rdfs:Class ;
  rdfs:label "protozoan gene" ;
  rdfs:subClassOf obo:OGG_0000000002 .

obo:VO_0000026 a rdfs:Class ;
  rdfs:label "pCMV4 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0018090 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution [Priorix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018085 .

obo:VO_0011233 a rdfs:Class ;
  rdfs:label "Kbeta" ;
  rdfs:comment "Two large fragments of PfKbeta representing the N- and C-terminal halves were expressed in E. coli. The recombinant proteins were highly immunogenic in mice, and also found to be the target for immune response in natural infections of Plasmodium spp.  Immunization with recombinant PfKbeta fragments was partially protective against a heterologous challenge infection in mice [PubMed: 15987343]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0003696 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2015-2016 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003694 .

obo:VO_0005087 a rdfs:Class ;
  rdfs:label "DelNS1-2019-nCoV-RBD-OPT1 vaccine" ;
  rdfs:comment "An influenza virus vector SARS-CoV-2 vaccine administered as an intranasal spray manufactured by University of Hong Kong, Xiamen University, and Beijing Wantai Biological Pharmacy." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0002167 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1775.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0003949 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated" ;
  rdfs:subClassOf obo:VO_0003948 .

obo:VO_0019984 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Afluria 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019971 .

obo:VO_0007459 a rdfs:Class ;
  rdfs:label "Leukemic Apoptotic Corpse-Pulsed Autologous Dendritic Cells Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with corpses of apoptotic leukemic cells, with potential immunostimulatory and antineoplastic activities. Upon vaccination, autologous dendritic cells pulsed with leukemic apoptotic corpse may activate the immune system to mount an anti-tumoral cytotoxic T-lymphocyte (CTL) response against leukemic cells expressing leukemia-associated antigens, which may result in leukemic cell lysis and inhibition of tumor cell growth. Apoptotic tumor cell corpses contain an array of tumor associated antigens" ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0018325 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0018296 , obo:VO_0018312 .

obo:VO_0004434 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine pNL3-MAGE-1-GM" ;
  rdfs:comment "Gene name: GM-CSF" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0004388 a rdfs:Class ;
  rdfs:label "Marburg virus recombinant vector vaccine CAdVax-Panfilo" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012163 .

obo:VO_0000998 a rdfs:Class ;
  rdfs:label "pGACAG DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pGACAG. The promoter is CAG and the antibiotics resistance gene is kanamycin." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003358 a rdfs:Class ;
  rdfs:label "Vivotif Pill" ;
  rdfs:subClassOf obo:VO_0003353 .

obo:VO_0015766 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Fendrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015587 .

obo:VO_0011377 a rdfs:Class ;
  rdfs:label "Bordetella pertussis BrkA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0016597 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0016585 .

obo:VO_0011056 a rdfs:Class ;
  rdfs:label "DnaX" ;
  rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.  DNA pol III Gamma and Tau (CP #1, dnaX) was found to be protective.  CP #1 (dnaX) was more protective than the live-vaccine, positive control.  [PubMed: 15811648]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:VO_0016393 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0003548 a rdfs:Class ;
  rdfs:label "Hepatovirus vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Hepatovirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0018405 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 19F vaccine 0.004 MG" ;
  rdfs:subClassOf obo:VO_0003224 .

obo:VO_0020120 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain Injection" ;
  rdfs:subClassOf obo:VO_0015052 .

obo:VO_0005261 a rdfs:Class ;
  rdfs:label "CoVepiT vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine by OSE Immunotherapeutics" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0017720 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 25 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017719 .

obo:VO_0002664 a rdfs:Class ;
  rdfs:label "wecA from Salmonella Typhimurium" ;
  rdfs:comment "A wecA mutant (DSM645) is attenuated in C57BL/6J mice through i.p. and oral immunization. This mutant also protects against challenge with S. typhimurium strains TML and SL1344 30 days after immunization" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0005488 a rdfs:Class ;
  rdfs:label "cervical cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against cervical cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0019360 a rdfs:Class ;
  rdfs:label "0.7 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010423 .

obo:VO_0001958 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44D5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002361 .

obo:VO_0016663 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by Abacus Medicine" ;
  rdfs:subClassOf obo:VO_0016626 .

obo:VO_0002222 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46E5.21)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002389 , obo:VO_0007748 .

obo:VO_0018884 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.0857 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0017868 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0018057 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 100 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018056 .

obo:VO_0001095 a rdfs:Class ;
  rdfs:label "passive immunization by injecting pre-made immune element" ;
  rdfs:comment "passive immunization by injecting a recipient with pre-made antibody, antitoxin, epitope, etc." ;
  rdfs:subClassOf obo:VO_0000492 .

obo:VO_0000157 a rdfs:Class ;
  rdfs:label "HIV gene" ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0005335 a rdfs:Class ;
  rdfs:label "SII B.1.617.2 vaccine" ;
  rdfs:comment "A SARS-CoV-2 monovalent protein subunit vaccine by Novavax immunizing against the B.1.617.2 (Delta) variant and containing the Matrix-M1 adjuvant" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0005294 a rdfs:Class ;
  rdfs:label "defective viral genome-derived oligonucleotide vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0006102 .

obo:VO_0016640 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0016621 .

obo:VO_0002997 a rdfs:Class ;
  rdfs:label "obsolete VEE Virus PE2/E1 mutant vaccine" ;
  rdfs:comment "A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE" .

obo:VO_0018278 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe [Rabipur]" ;
  rdfs:subClassOf obo:VO_0018256 , obo:VO_0018265 , obo:VO_0018285 .

obo:VO_0020475 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe" .

obo:VO_0005369 a rdfs:Class ;
  rdfs:label "dibutyl phthalate vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0007308 a rdfs:Class ;
  rdfs:label "Autologous NSCLC DNA-Transfected Semi-Allogeneic Fibroblasts MRC-5 Vaccine" ;
  rdfs:comment "A vaccine consisting of irradiated human fetal lung fibroblasts (Medical Research Council 5 or MRC-5) transfected with autologous non-small cell lung cancer (NSCLC)-derived DNA with potential immunostimulatory and antineoplastic activities. Upon administration, autologous NSCLC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine expresses NSCLC tumor-associated antigens (TAAs) in addition to MHC class I-determinants and the co-stimulatory molecule B7.1, which may induce a cytotoxic T-lymphocyte (CTL) response against NSCLC cells. The MRC-5 cell line is a human diploid lung fibroblast cell line extablished in 1966." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 , obo:VO_0007660 .

obo:OPL_0000401 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii merozoite stage" ;
  rdfs:comment "A merozoite stage in the Plasmodium yoelii." ;
  rdfs:subClassOf obo:OPL_0000036 , obo:OPL_0000292 , obo:OPL_0000415 .

obo:VO_0017326 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0017669 , obo:VO_0020836 .

obo:VO_0007185 a rdfs:Class ;
  rdfs:label "4-peptide melanoma vaccine" ;
  rdfs:comment "A cancer vaccine that may stimulate an immune response against 4 different melanoma associated antigens. This may lead to a reduction in tumor cell proliferation of cancer cells expressing these antigens. The vaccine may contain 4 class I MHC-restricted synthetic melanoma peptides (1 each restricted by HLA-A1, -A3, and two restricted by HLA-A2) and a helper tetanus peptide. The peptides may include Melan-A, gp100, MAGE-3, and NA17. The vaccine can be used in combination Ontak, which may produce an immune response in patients with metastatic melanoma, and the Ontak may improve these immune responses and lead to tumor shrinkage." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0003870 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.07 MG/ML" ;
  rdfs:subClassOf obo:VO_0003845 .

obo:VO_0017445 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015014 , obo:VO_0020836 .

obo:VO_0001786 a rdfs:Class ;
  rdfs:label "Chlamydia Psittaci Killed Chlamydia Vaccine (USDA: 1585.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001214 , obo:VO_0001473 , obo:VO_0007748 , obo:VO_0012174 .

obo:VO_0010313 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003498 , obo:VO_0010297 .

obo:VO_0019562 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [FluLaval Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003763 , obo:VO_0010427 , obo:VO_0019544 .

obo:VO_0000037 a rdfs:Class ;
  rdfs:label "adenovirus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection of an adenovirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0020212 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.015 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020211 .

obo:VO_0003295 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003344 .

obo:VO_0006095 a rdfs:Class ;
  rdfs:label "SMNP vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant that includes AS01-mimic, Immune Stimulating Complex (ISCOM) with a TLR4 agonist." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0001341 a rdfs:Class ;
  rdfs:label "DL-PGL (Polyester poly (DL-lactide-co-glycolide)) vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is PLGA, which has been used in the controlled delivery of peptide drugs." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0005321 a rdfs:Class ;
  rdfs:label "COVID-19 subunit vaccine by HIPRA" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine by Laboratorios HIPRA" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0001939 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0020460 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020444 .

obo:VO_0001222 a rdfs:Class ;
  rdfs:label "Newcastle disease virus vaccine" ;
  rdfs:comment "A viral vaccine that protects aganist Newcastle disease virus infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 , obo:VO_0001468 .

obo:UBERON_0000061 a rdfs:Class ;
  rdfs:label "anatomical structure" ;
  rdfs:comment "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:VO_0007533 a rdfs:Class ;
  rdfs:label "ESO-1 (161-180) peptide vaccine" ;
  rdfs:comment "A recombinant 19-residue peptide vaccine consisting of amino acids 161 through 180 of the cancer/testis (CT) antigen. ESO-1 (161-180) peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for ESO-1, resulting in decreased tumor growth. ESO-1 is expressed in a variety of cancers, including melanoma, breast, bladder, prostate, and hepatocellular cancers. (NCI04) (NCIT_C28775)." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0005425 , obo:VO_0005484 , obo:VO_0005485 , obo:VO_0005499 , obo:VO_0007657 .

obo:NCBITaxon_10787 a rdfs:Class ;
  rdfs:label "Feline panleukopenia virus (strain 193)" ;
  rdfs:subClassOf obo:NCBITaxon_10786 .

obo:NCBITaxon_29176 a rdfs:Class ;
  rdfs:label "Neospora caninum" ;
  rdfs:subClassOf obo:NCBITaxon_5809 .

obo:VO_0005285 a rdfs:Class ;
  rdfs:label "MiT4 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0001746 a rdfs:Class ;
  rdfs:label "canine influenza H3N8, killed virus vaccine (USDA: 15K5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001471 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0000341 a rdfs:Class ;
  rdfs:label "intranasal route" ;
  rdfs:comment "A rounte of administration that located in nose." ;
  rdfs:subClassOf obo:VO_0000574 .

obo:PR_000001158 a rdfs:Class ;
  rdfs:label "Toll-like receptor 7" ;
  rdfs:comment "A Toll-like receptor that is a translation product of the human TLR7 gene or a 1:1 ortholog thereof." ;
  rdfs:subClassOf obo:PR_000001096 .

obo:VO_0004725 a rdfs:Class ;
  rdfs:label "ALVAC-AHSV vaccine" ;
  rdfs:subClassOf obo:VO_0001480 .

obo:VO_0002773 a rdfs:Class ;
  rdfs:label "obsolete Actinobacillus pleuropneumoniae apxIIC and apxIVA double deletion mutant vaccine" ;
  rdfs:comment "A precisely defined DeltaapxIICDeltaapxIVA double-deletion mutant of A. pleuropneumoniae was constructed based on HB04C(-) by transconjugation and counterselection. The results demonstrated that the DeltaapxIICDeltaapxIVA double mutant strain was less virulent than HB04C(-). Despite attenuation of virulence, the DeltaapxIICDeltaapxIVA double mutant remains immunogenic and conferred a similar level of protective immunity to pigs against challenge with a lethal dose of a heterologous fully virulent standard serovar 1 strain of A. pleuropneumoniae. (Reference: PubMed: 17767980)" .

obo:VO_0001508 a rdfs:Class ;
  rdfs:label "Feline immunodeficiency virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Feline immunodeficiency virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0016003 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0003424 .

obo:VO_0004737 a rdfs:Class ;
  rdfs:label "ALVAC-HIV-2- env/gag/pol vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0001489 a rdfs:Class ;
  rdfs:label "canine adenovirus type 1 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Canine adenovirus type 1 (Canine adenovirus 1) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000037 .

obo:VO_0016766 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0016718 .

obo:VO_0000463 a rdfs:Class ;
  rdfs:label "Coxiella burnetii vaccine" ;
  rdfs:comment "Bacterial vaccine against infection with Coxiella burnetii which causes Q fever" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0016480 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0000496 a rdfs:Class ;
  rdfs:label "disorder prevention" ;
  rdfs:comment "Process that prevents a disorder that is the physical basis of a disease." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0017507 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017482 , obo:VO_0017506 .

obo:VO_0001615 a rdfs:Class ;
  rdfs:label "Bronchitis Conn Type, Live Virus Vaccine (USDA: 1231.15)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0001106 a rdfs:Class ;
  rdfs:label "swinepox virus vaccine vector" ;
  rdfs:comment "a poxvirus vaccine vector that uses a swinepox virus as the vector" ;
  rdfs:subClassOf obo:VO_0000447 .

obo:VO_0019461 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 4 UNT/ML [Tdvax]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0003491 a rdfs:Class ;
  rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010305 , obo:VO_0010415 .

obo:VO_0019334 a rdfs:Class ;
  rdfs:label "0.5 ML measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML Injection [Attenuvax]" ;
  rdfs:subClassOf obo:VO_0019333 , obo:VO_0020119 .

obo:VO_0016947 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 4 LFU/ML Injection" ;
  rdfs:subClassOf obo:VO_0017405 .

obo:VO_0004866 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.005 MG/ML / meningococcal group C polysaccharide 0.01 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.01 MG/ML [MenHibrix]" ;
  rdfs:subClassOf obo:VO_0000031 , obo:VO_0000561 .

obo:VO_0020680 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus / Influenza Virus Vaccine, Inactivated A-Christchurch-16-2010 NIB-74 (H1N1) (A-California-7-2009) strain / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0003131 a rdfs:Class ;
  rdfs:label "VPM1002 vaccine" ;
  rdfs:comment "A TB vaccine that recombinant BCG strain with the replacment of its urease C encoding gene with the listeriolysin encoding gene from Listeria monocytogenes." ;
  rdfs:subClassOf obo:VO_0000603 .

obo:VO_0010843 a rdfs:Class ;
  rdfs:label "Hendra virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0000506 a rdfs:Class ;
  rdfs:label "vaccine organism" ;
  rdfs:comment "an organism that is used as part of a vaccine" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:VO_0003757 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 , obo:VO_0010432 .

obo:VO_0002724 a rdfs:Class ;
  rdfs:label "UL29 from Herpes simplex virus type 1 and 2" ;
  rdfs:comment "A UL29 mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001437 .

obo:VO_0004069 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae 6PGD protein vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0005245 a rdfs:Class ;
  rdfs:label "DS-5670a vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine manufactured by Daiichi Sankyo Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0002107 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.28)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0019165 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0000965 a rdfs:Class ;
  rdfs:label "potato expressed E. coli LB-T vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0000558 a rdfs:Class ;
  rdfs:label "recombinant nontypeable Haemophilus influenzae protein P6 vaccine with AdDP adjuvant" ;
  rdfs:subClassOf obo:VO_0000471 , obo:VO_0000484 .

obo:VO_0018681 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML Oral Suspension" ;
  rdfs:subClassOf obo:VO_0018679 , obo:VO_0020187 .

obo:VO_0017214 a rdfs:Class ;
  rdfs:label "10 ML tetanus toxoid vaccine, inactivated 8 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017211 , obo:VO_0017588 .

obo:VO_0004346 a rdfs:Class ;
  rdfs:label "SIV DNA vaccine pSIVgag and pmacIL-15 encoding SIV core protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000751 .

obo:VO_0015719 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 250" ;
  rdfs:subClassOf obo:VO_0015572 , obo:VO_0015798 .

obo:VO_0018676 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 Powder for Oral Suspension [Rotarix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018675 , obo:VO_0018678 .

obo:VO_0020576 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Influsplit] Box of 20" ;
  rdfs:subClassOf obo:VO_0020573 , obo:VO_0020606 , obo:VO_0020871 .

obo:NCBITaxon_11244 a rdfs:Class ;
  rdfs:label "Pneumoviridae" ;
  rdfs:subClassOf obo:NCBITaxon_11157 .

obo:VO_0004073 a rdfs:Class ;
  rdfs:label "GP and NP vaccine" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0012389 a rdfs:Class ;
  rdfs:label "CNA" ;
  rdfs:comment "Mice were immunized with a recombinant fragment of CNA protein, and were then challenged  with the S. aureus clinical isolate strain Phillips. At 14 d after inoculation, mortality in the collagen adhesin-vaccinated group was only 13%, compared with 87% in the control antigen immunized group [PubMed: 9637697]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012355 .

obo:VO_0003012 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii mic2 mutant vaccine" ;
  rdfs:comment "A mic2 mutant is attenuated in mice and induces protection from challenge with wild type T. gondii" ;
  rdfs:subClassOf obo:VO_0000994 .

obo:VO_0007688 a rdfs:Class ;
  rdfs:label "MART-1, tyrosinase and MAGE-A6 autologous DC vaccine" ;
  rdfs:comment "A cancer vaccine made with autologous dendritic cells (DC) are transduced with the MART-1, tyrosinase and MAGE-A6 (melanoma associated antigens, MAA) genes for melanoma patients. Some patients also receive interferon-alfa 2b (IFN) intravenously." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0021135 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Washington/19/2020 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020334 .

obo:VO_0005205 a rdfs:Class ;
  rdfs:label "COVID-19 virus-like particle vaccine" ;
  rdfs:subClassOf obo:VO_0004908 , obo:VO_0004914 .

obo:VO_0019230 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020495 .

obo:VO_0004883 a rdfs:Class ;
  rdfs:label "Menomune A/C/Y/W-135 Vaccine Injection" ;
  rdfs:subClassOf obo:VO_0004870 .

obo:VO_0018636 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injectable Solution [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0011558 , obo:VO_0018635 .

obo:VO_0003937 a rdfs:Class ;
  rdfs:label "GARDASIL 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003936 .

obo:VO_0015309 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 10" ;
  rdfs:subClassOf obo:VO_0015307 , obo:VO_0015311 .

obo:VO_0003310 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 14 vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003219 .

obo:VO_0016319 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 3 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015933 .

obo:VO_0004036 a rdfs:Class ;
  rdfs:label "Ebola virus DNA vaccine EBOV GP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000726 .

obo:VO_0004141 a rdfs:Class ;
  rdfs:label "Zoosaloral H. vaccine" ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0000367 a rdfs:Class ;
  rdfs:label "live attenuated vaccine" ;
  rdfs:comment "A vaccine that is made from microbes that have been attenuated (weakened) in the laboratory so that they can't cause disease." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:IAO_0000064 a rdfs:Class ;
  rdfs:label "algorithm"@en ;
  rdfs:comment "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:VO_0001186 a rdfs:Class ;
  rdfs:label "vaccine investigation data set" ;
  rdfs:comment "A data set that represents a set of data for a list of variables (e.g., vaccination dose) for the data analysis of an vaccine investigation study." ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:VO_0007587 a rdfs:Class ;
  rdfs:label "BCG and Corynebacterium parvum for malignant melanoma vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0004718 a rdfs:Class ;
  rdfs:label "rCMV-TT vaccine" ;
  rdfs:subClassOf obo:VO_0000640 .

obo:VO_0001541 a rdfs:Class ;
  rdfs:label "Feline calicivirus Modified Live Virus Vaccine (USDA: 15C1.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001220 , obo:VO_0001509 , obo:VO_0007748 .

obo:VO_0003178 a rdfs:Class ;
  rdfs:label "Quatro Virelon vaccine" ;
  rdfs:comment "Active immunization against tetanus, diphtheria, pertussis, and poliomyelitis for individuals between 3 months and 6 years of age." ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 .

obo:VO_0010971 a rdfs:Class ;
  rdfs:label "SurA" ;
  rdfs:comment "Brucella SurA is a protective antigen [PubMed: 17686554]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0000555 a rdfs:Class ;
  rdfs:label "titer" ;
  rdfs:comment "A titer (or titre) is a measure of concentration. Titer testing employs serial dilution to obtain approximate quantitative information from an analytical procedure that inherently only evaluates as positive or negative. The titer corresponds to the highest dilution factor that still yields a positive reading; for example, positive readings in the first 8 serial twofold dilutions translate into a titer of 1:256." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0019785 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0001816 a rdfs:Class ;
  rdfs:label "Bluetongue Modified Live Virus Vaccine (USDA: 1061.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000503 , obo:VO_0001220 , obo:VO_0001515 , obo:VO_0007748 .

obo:VO_0016369 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0003718 a rdfs:Class ;
  rdfs:label "afluria 2015-2016 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003716 .

obo:VO_0016828 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0016735 , obo:VO_0016777 .

obo:VO_0005505 a rdfs:Class ;
  rdfs:label "vaccine by mode of production" ;
  rdfs:comment "Vaccine that is developed and produced by specific technology or method." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0016986 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 160 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution [T Polio Adsorbed] by Aventis" ;
  rdfs:subClassOf obo:VO_0016985 .

obo:VO_0000930 a rdfs:Class ;
  rdfs:label "polysorbate 80 vaccine emulsifier" ;
  rdfs:comment "a vaccine emulsifier that uses polysorbate 80, also known as polyoxyethylene sorbitan monooleate or Tween(TM) 80." ;
  rdfs:subClassOf obo:VO_0000310 .

obo:VO_0015075 a rdfs:Class ;
  rdfs:label "intramuscular solution" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:VO_0019910 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluzone High-Dose 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020484 .

obo:CHEBI_15882 a rdfs:Class ;
  rdfs:label "phenol" ;
  rdfs:comment "An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0017797 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine Injectable Solution [Pa Vaccinol]" ;
  rdfs:subClassOf obo:VO_0017808 .

obo:VO_0001259 a rdfs:Class ;
  rdfs:label "killed Corynebacterium parvum vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant derived from heat-killed Corynebacterium parvum." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0005014 a rdfs:Class ;
  rdfs:label "pNGVL4a DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pNGVL4a.  This plasmid has a CMV promoter and kanamycin and ampicillin resistance genes." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0004057 a rdfs:Class ;
  rdfs:label "Streptococcus pyogenes Sib35 protein vaccine" ;
  rdfs:subClassOf obo:VO_0002852 .

obo:VO_0003909 a rdfs:Class ;
  rdfs:label "influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010316 , obo:VO_0010415 .

obo:VO_0017998 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injection Box of 10 by Saudi" ;
  rdfs:subClassOf obo:VO_0017997 .

obo:VO_0003183 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine foreign to USA" ;
  rdfs:comment "A Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine manufactured outside of the U.S" ;
  rdfs:subClassOf obo:VO_0000743 , obo:VO_0003444 .

obo:VO_0010328 a rdfs:Class ;
  rdfs:label "Varicella zoster virus glycoprotein E, recombinant vaccine" ;
  rdfs:subClassOf obo:VO_0000669 , obo:VO_0010326 .

obo:VO_0000681 a rdfs:Class ;
  rdfs:label "Shigella dysenteriae vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000769 .

obo:VO_0002653 a rdfs:Class ;
  rdfs:label "phoP from Salmonella Typhi" ;
  rdfs:comment "Three S. typhi deletion mutants (phoP, rpoS, and rpoS-phoP double mutant) were constructed and characterized with respect to invasiveness, virulence, and protective immune response compared with wild-type Ty2. All S. typhi mutants showed an increase in the specific serum IgG levels and T-cell-mediated immunity, and showed equal protection abilities against a wild-type Ty2 challenge after two rounds of immunization in BALB/c mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001419 .

obo:VO_0002986 a rdfs:Class ;
  rdfs:label "Pseudorabies virus gp50/gp63 mutant vaccine" ;
  rdfs:comment "A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky's disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3" ;
  rdfs:subClassOf obo:VO_0000750 .

obo:VO_0015769 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015593 .

obo:VO_0019122 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0002392 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Vaccine-Borrelia Burgdorferi Bacterin" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000563 , obo:VO_0000764 , obo:VO_0001468 , obo:VO_0004897 .

obo:NCBITaxon_2732415 a rdfs:Class ;
  rdfs:label "Cossaviricota" ;
  rdfs:subClassOf obo:NCBITaxon_2732092 .

obo:VO_0002211 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4637.29)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002409 , obo:VO_0007748 .

obo:VO_0016566 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Twinrix Adult]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0016557 .

obo:VO_0003601 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen" ;
  rdfs:comment "RXAUI: 10279285" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0019546 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003721 , obo:VO_0019544 .

obo:VO_0001197 a rdfs:Class ;
  rdfs:label "animal age at vaccination in days" ;
  rdfs:comment "An age range at vaccination that represents the animal age (unit: day) at the time of vaccination." ;
  rdfs:subClassOf obo:VO_0004926 .

obo:VO_0020550 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluad] by Novartis" ;
  rdfs:subClassOf obo:VO_0020547 .

obo:VO_0002831 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda aroC/slyA mutant vaccine" ;
  rdfs:comment "An aroC and slyA mutant is attenuated in zebra fish. This mutant is also protective against challenge from wild type E. tarda, resulting in a relative percent survival of 80.1%" ;
  rdfs:subClassOf obo:VO_0002506 .

obo:VO_0002249 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.23)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002422 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0005054 a rdfs:Class ;
  rdfs:label "pCDL-SRa296 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCDL-SRa296.  This plasmid is 3700 base pairs in length and contains a SRalpha promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015751 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 50" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015816 .

obo:VO_0001519 a rdfs:Class ;
  rdfs:label "Mycobacterium bovis vaccine" ;
  rdfs:comment "A vaccine that protects against infection with Mycobacterium bovis" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000077 .

obo:VO_0018102 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0018098 , obo:VO_0018236 .

obo:VO_0018485 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0018442 .

obo:VO_0019745 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2022 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020494 .

obo:VO_0016510 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 1 by European" ;
  rdfs:subClassOf obo:VO_0016057 .

obo:VO_0015299 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML [Vaqta]" ;
  rdfs:subClassOf obo:VO_0010745 , obo:VO_0015298 .

obo:VO_0018640 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0003948 , obo:VO_0018614 .

obo:NCBITaxon_39744 a rdfs:Class ;
  rdfs:label "Rubulavirus" ;
  rdfs:subClassOf obo:NCBITaxon_2560080 .

obo:VO_0016405 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0015037 a rdfs:Class ;
  rdfs:label "Gardasil 9 injection" ;
  rdfs:subClassOf obo:VO_0003075 .

obo:VO_0018490 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 20 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0018459 .

obo:VO_0003758 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2016-2017 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003757 .

obo:VO_0011253 a rdfs:Class ;
  rdfs:label "SAG1 from Sarcocystis neurona" ;
  rdfs:comment "Horses were vaccinated with adjuvanted recombinant SnSAG1 (rSnSAG1)and 5 control (sham vaccinated) horses were vaccinated with adjuvant only.  The effect of vaccination with rSnSAG1 on in vivo infection by S. neurona was evaluated by challenging all the horses with S. neurona merozoites. The study showed that vaccination with rSnSAG-1 produced antibodies in horses that neutralized merozoites when tested by in vitro culture and significantly reduced clinical signs demonstrated by in vivo challenge [PubMed: 19794889]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010830 .

obo:VO_0015799 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 3" ;
  rdfs:subClassOf obo:VO_0015492 .

obo:VO_0000630 a rdfs:Class ;
  rdfs:label "licensed vaccine role" ;
  rdfs:comment "A licensed vaccine role is a regulation-assigned role that indicates that a vaccine obtains official approval for commercial production and selling on the market." ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0020136 a rdfs:Class ;
  rdfs:label "mumps virus vaccine live, Jeryl Lynn strain 40000 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020132 .

obo:OPL_0000036 a rdfs:Class ;
  rdfs:label "merozoite stage" ;
  rdfs:comment "A parasite lifecycle stage of apicomplexan species where a daughter cell, called merozoite is produced from schizont through schizogony." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0010892 a rdfs:Class ;
  rdfs:label "RplF" ;
  rdfs:comment "Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection.  In addition, RplF was able to engender protective immunity against challenge with C. muridarum [PubMed: 19155509]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010795 .

obo:VO_0020619 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0020617 .

obo:VO_0020723 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020721 , obo:VO_0020735 .

obo:VO_0019872 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Flulaval 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020340 .

obo:VO_0015329 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated 320 UNT/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0015322 .

obo:VO_0007742 a rdfs:Class ;
  rdfs:label "TVI-Brain-1 vaccine" ;
  rdfs:comment "A cancer vaccine made as the patient's cancer will be surgically removed to provide cells for the vaccine, then the patient will be vaccinated twice with those cells and GM-CSF. After, the patient's blood will be filtered for white cells which will then be cultured and stimulated to reach a higher (killer) activity level. Next, the activated white blood cells will be infused into the patient's bloodstream so that they will be able to attack the cancer. Lastly, the entire process starting with vaccination will be repeated, for a total of two rounds of therapy. The autologous vaccine-enhanced ex vivo activated cancer neoantigens-specific T-cells TVI-Brain-1 recognize and bind to tumor cells expressing the cancer neoantigens, resulting in a cytotoxic T-lymphocyte (CTL)-mediated immune response against the patient's tumor cells." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0005005 a rdfs:Class ;
  rdfs:label "VRC-9123 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label VRC-9123." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001117 a rdfs:Class ;
  rdfs:label "persistence of vaccine induced immune response" ;
  rdfs:comment "Persistence of vaccine induced immune response is a processual entity that indicates the persistence of an immune reponse induced by a vaccine in a vaccinated host." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0001283 a rdfs:Class ;
  rdfs:label "obsolete immunization target role of parasite pathogen" .

obo:VO_0010948 a rdfs:Class ;
  rdfs:label "B. melitensis M5 P39" ;
  rdfs:comment "The 39-kDa protein is  immunogenic." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0011211 a rdfs:Class ;
  rdfs:label "binding protein Eag" ;
  rdfs:comment "Vaccination of mice with EAG (2-macroglobulin, albumin, and immunoglobulin G [IgG] binding protein) as a single antigen with EtxB (as an adjuvant) induced protection in mice against bacterial challenge, but was less protective than at affording protection than immunization with FNZ, SFS, EAG, and EtxB [PubMed: 15155624]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010816 .

obo:VO_0004232 a rdfs:Class ;
  rdfs:label "V3 VLPs vaccine with Gamma inulin adjuvant" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0018699 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain Powder for Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0010738 , obo:VO_0018698 .

obo:VO_0021042 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution [Varivax]" ;
  rdfs:subClassOf obo:VO_0000119 , obo:VO_0021040 .

obo:VO_0002320 a rdfs:Class ;
  rdfs:label "Infectious Salmon Anemia Virus Killed Virus Vaccine-Aeromonas Salmonicida-Vibrio Anguillarum-Ordalii-Salmonicida Bacterin (USDA: 4A45.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000645 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002442 , obo:VO_0007748 .

obo:VO_0002888 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine (merged to VO_0002885)" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" .

obo:VO_0019949 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluvirin 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020477 .

obo:VO_0017723 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017714 .

obo:DOID_1586 a rdfs:Class ;
  rdfs:label "rheumatic fever"@en ;
  rdfs:comment "A connective tissue disease that develops from an antecedent Group A Streptococcal pharyngeal infection and has_symptom carditis, has_symptom polyarthritis, has_symptom chorea, has_symptom erythema marginatum, has_symptom subcutaneous nodules, has_symptom arthralgia, has_symptom prolonged PR interval, and/or has_symptom fever."@en ;
  rdfs:subClassOf obo:DOID_104 .

obo:VO_0001722 a rdfs:Class ;
  rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000620 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0000648 a rdfs:Class ;
  rdfs:label "Yersinia pestis vaccine" ;
  rdfs:comment "A bacteria vaccine that prevents against Yersinia pestis infection that causes plague." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000601 .

obo:VO_0001757 a rdfs:Class ;
  rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012180 .

obo:VO_0018920 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0020920 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0020913 .

obo:NCBITaxon_10241 a rdfs:Class ;
  rdfs:label "Chordopoxvirinae" ;
  rdfs:subClassOf obo:NCBITaxon_10240 .

obo:VO_0003120 a rdfs:Class ;
  rdfs:label "MVA85A vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0000918 a rdfs:Class ;
  rdfs:label "EURIFEL FeLV vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000843 .

obo:VO_0003724 a rdfs:Class ;
  rdfs:label "Afluria 2016-2017 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003722 .

obo:VO_0001620 a rdfs:Class ;
  rdfs:label "Bronchitis Mass & Ark Types, Live Virus Vaccine (USDA: 1231.13)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0017620 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0017593 , obo:VO_0017610 .

obo:VO_0019904 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Flucelvax 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020330 .

obo:VO_0012370 a rdfs:Class ;
  rdfs:label "PstS3" ;
  rdfs:comment "Mice vaccinated with PstS-3 DNA demonstrated significant and sustained reduction in bacterial CFU numbers in spleen and lungs for 3 mo after M. tuberculosis challenge, as compared with CFU counts in mice vaccinated with control DNA [PubMed: 9916741]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0001530 a rdfs:Class ;
  rdfs:label "Canary Pox Modified Live Virus Vaccine (USDA: 1623.10)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001220 , obo:VO_0001517 , obo:VO_0007748 .

obo:VO_0019431 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Decavac]" ;
  rdfs:subClassOf obo:VO_0000030 , obo:VO_0018788 .

obo:VO_0002486 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea-Respiratory Syncytial Virus vaccine" ;
  rdfs:subClassOf obo:VO_0001466 , obo:VO_0001501 , obo:VO_0001507 .

obo:VO_0018559 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution [Typhim VI] by Sanofi" ;
  rdfs:subClassOf obo:VO_0018556 .

obo:VO_0001797 a rdfs:Class ;
  rdfs:label "Lawsonia Intracellularis Avirulent Live Culture Vaccine (USDA: 10L1.02)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001105 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0010960 a rdfs:Class ;
  rdfs:label "S nucleocapsid protein from Dobrava-Belgrade virus" ;
  rdfs:comment "Study compared the immunogenicity and protective efficacy of recombinant DOBV nucleocapsid protein (rDOBV N, S) given with Alum or Freund's as adjuvant, or PBS, in C57/BL6 mice.   Mice receiving rDOBV N with Freund's adjuvant were protected from challenge (75% protected) [PubMed: 15364453]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010768 .

obo:VO_0007319 a rdfs:Class ;
  rdfs:label "autologous tumor cell vaccine" ;
  rdfs:comment "A therapeutic agent produced by isolating tumor cells from an individual and processing these tumor cells into a vaccine formulation in vitro; the vaccine is then administered to the individual from whom the tumor cells were isolated. Typically combined with an adjuvant immunostimulant, an autologous cell vaccine may elicit a cytotoxic T-lymphocytic immune response to cell surface-expressed tumor-associated antigens (TAAs), resulting in tumor cell death." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005427 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0016282 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015925 .

obo:VO_0005081 a rdfs:Class ;
  rdfs:label "Corbevax vaccine" ;
  rdfs:comment "A SARS-CoV-2 vaccine that includes a protein antigen, SARS-CoV-2 Spike RBD, adsorbed to the adjuvant Alhydrogel (Alum), in combination with another approved adjuvant, CpG 1018" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0012399 a rdfs:Class ;
  rdfs:label "GlpQ" ;
  rdfs:comment "Immunization with the recombinant GlpQ significantly protected rabbits from subsequent T. pallidum challenge, altering lesion development at the sites of challenge [PubMed: 9826352]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012358 .

obo:NCBITaxon_55601 a rdfs:Class ;
  rdfs:label "Vibrio anguillarum" ;
  rdfs:subClassOf obo:NCBITaxon_662 .

obo:VO_0004091 a rdfs:Class ;
  rdfs:label "LC16m8 vaccine" ;
  rdfs:subClassOf obo:VO_0000651 .

obo:VO_0019774 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0001409 a rdfs:Class ;
  rdfs:label "Bordetella pertussis gene" ;
  rdfs:comment "A bacterial gene that is from Bordetella pertussis." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0010486 a rdfs:Class ;
  rdfs:label "licensed human Rift Valley Fever virus vaccine" ;
  rdfs:comment "Rift Valley Fever virus vaccine that is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0012166 .

obo:VO_0007630 a rdfs:Class ;
  rdfs:label "KSA-KLH conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0007657 .

obo:VO_0011286 a rdfs:Class ;
  rdfs:label "HASPB1" ;
  rdfs:comment "Following infection with L. infantum promastigotes, four out of eight beagle dogs immunized with HASPB1 Montanide remained free of clinical signs, compared to two out of eight dogs in the control group.  The results demonstrate that HASPB1 antigens with Montanide were able to induce partial protection against canine leishmaniasis, even under extreme experimental challenge conditions [PubMed: 17576026]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010836 .

obo:NCBITaxon_3072906 a rdfs:Class ;
  rdfs:label "Musteloidea" ;
  rdfs:subClassOf obo:NCBITaxon_379584 .

obo:VO_0002735 a rdfs:Class ;
  rdfs:label "glycoprotein M from Pseudorabies virus" ;
  rdfs:comment "A glycoprotein M, gM, deletion in pseudorabies virus was attenuated and induced protection in piglets against intranasal challenge with 108 p.f.u. of the highly virulent PrV strain NIA-3" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001442 .

obo:VO_0000976 a rdfs:Class ;
  rdfs:label "extraintestinal pathogenic E. coli vaccine" ;
  rdfs:comment "An E. coli vaccine against extraintestinal pathogenic E. coli infections" ;
  rdfs:subClassOf obo:VO_0000041 .

obo:VO_0016358 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:NCBITaxon_10512 a rdfs:Class ;
  rdfs:label "Canine adenovirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_10537 .

obo:VO_0016062 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015672 , obo:VO_0015819 .

obo:VO_0007584 a rdfs:Class ;
  rdfs:label "Bacillus Calmette-Guerin (BCG), dinitrochlorobenzene (DNCB) vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0019323 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.12 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0002768 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae ureC and apxIIA double mutant deletion vaccine" ;
  rdfs:comment "Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0016539 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0001841 a rdfs:Class ;
  rdfs:label "Feline Immunodeficiency-Leukemia Virus Killed Virus Vaccine (USDA: 15D5.R0)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0002427 , obo:VO_0007748 .

obo:VO_0020894 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Grippeimpfstoff Ratiopharm]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0000373 a rdfs:Class ;
  rdfs:label "Brucella recombinant DnaK protein vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0001221 .

obo:VO_0018717 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010451 .

obo:VO_0017600 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 2" ;
  rdfs:subClassOf obo:VO_0017597 , obo:VO_0017606 .

obo:VO_0016950 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 4 LFU/ML Injection by Massbiologics" ;
  rdfs:subClassOf obo:VO_0016947 .

obo:VO_0021083 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.006 MG/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Vaxelis]" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0000746 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0007629 a rdfs:Class ;
  rdfs:label "irradiated melanoma cells plus BCG vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020390 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 10000000000 UNT Delayed Release Oral Capsule [Vivotif]" ;
  rdfs:subClassOf obo:VO_0003353 , obo:VO_0020397 .

obo:VO_0018659 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML Injectable Suspension [Cervarix] Box of 1" ;
  rdfs:subClassOf obo:VO_0011559 , obo:VO_0018660 , obo:VO_0018805 .

obo:VO_0003403 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0019826 a rdfs:Class ;
  rdfs:label "influenza A virus A/North Carolina/04/2016 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020331 .

obo:VO_0005151 a rdfs:Class ;
  rdfs:label "SARS-CoV Baculovirus S protein Vaccine" ;
  rdfs:comment "A SARS-CoV recombinant vector made from a baculovirus vector expressing SARS-CoV S protein." ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0011344 a rdfs:Class ;
  rdfs:label "OmpU" ;
  rdfs:comment "Asian seabass vaccinated with the OMP38 (OmpU) DNA vaccine was challenged with pathogenic V. anguillarum by intramuscular injection. A relative percent survival (RPS) rate of 55.6% was recorded [PubMed: 17337208]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010815 .

obo:VO_0004289 a rdfs:Class ;
  rdfs:label "Bovine Respiratory Syncytial Virus recombinant vector vaccine BHVl/BRSVG encoding the G protein" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0001466 , obo:VO_0001507 .

obo:VO_0019734 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluad Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020313 .

obo:VO_0011167 a rdfs:Class ;
  rdfs:label "F fusion protein from Measles virus" ;
  rdfs:comment "Mice vaccinated with a vaccinia virus recombinant encoding the fusion protein of Measles virus developed measles neutralizing antibodies.  The mice also resisted a normally lethal intracerebral inoculation of a cell-associated measles virus subacute sclerosing panencephalitis strain [PubMed: 3422488]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010784 .

obo:VO_0020757 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain Injection" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017681 .

obo:VO_0019424 a rdfs:Class ;
  rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.08 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 12 UNT/ML Injectable Suspension [Certiva]" ;
  rdfs:subClassOf obo:VO_0003122 , obo:VO_0019423 .

obo:VO_0017987 a rdfs:Class ;
  rdfs:label "0.5 ML poliomyelitis virus type 1 brunhilde 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018016 .

obo:VO_0015264 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0003236 , obo:VO_0015263 .

obo:VO_0017235 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella Pertussis Filamentous Haemagglutinin Antigen / diphtheria toxoid vaccine, inactivated / pertactin adsorbed / tetanus toxoid vaccine, inactivated Injection [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 , obo:VO_0017234 .

obo:DOID_11338 a rdfs:Class ;
  rdfs:label "tetanus"@en ;
  rdfs:comment "A primary bacterial infectious disease that results in prolonged contraction of skeletal muscle fibers, has_material_basis_in Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord, where it binds irreversibly to receptors inhibiting neurotransmission. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:VO_0011363 a rdfs:Class ;
  rdfs:label "Cancer Her-2/neu Protein Subunit Vaccine" ;
  rdfs:comment "Gene name: ERBB2" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0003177 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-ACT-Hib vaccine" ;
  rdfs:comment "A vaccine that contains ActHIB and protects against, Diphtheria, Tetanus, Pertussis (whooping cough), Polio, and Haemophilus influenzae type b." ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000744 .

obo:VO_0019148 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Pentacel]" ;
  rdfs:subClassOf obo:VO_0000084 , obo:VO_0020832 .

obo:VO_0015064 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0018778 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010447 .

obo:VO_0016913 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.0936 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017294 .

obo:VO_0015050 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injection [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0015051 .

obo:VO_0019133 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:VO_0001063 a rdfs:Class ;
  rdfs:label "Maraba virus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a Maraba virus strain" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0001626 a rdfs:Class ;
  rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.1A)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0011269 a rdfs:Class ;
  rdfs:label "TviB" ;
  rdfs:comment "The viaB (tviB) gene coding for the Vi antigen of Salmonella typhi Ty2 was subcloned into expression vector pYA248. The recombinant plasmid was termed SMM202 and transformed into Salmonella typhimurium 4072, an attenuated crp mutant.  Immunization of mice with Vi4072 afforded complete protection against fatal infection with virulent S. typhi Ty2 [PubMed: 1612747]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010776 .

obo:VO_0002616 a rdfs:Class ;
  rdfs:label "aroD from Salmonella Typhi" ;
  rdfs:comment "Inactivation of AroD results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001419 .

obo:VO_0020184 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 667000 UNT/ML [Rotarix]" ;
  rdfs:subClassOf obo:VO_0010738 , obo:VO_0020183 .

obo:VO_0019720 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0004006 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae ClpP protein vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0001719 a rdfs:Class ;
  rdfs:label "Newcastle Disease Killed Virus Vaccine (USDA: 1705.15)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001222 , obo:VO_0007748 .

obo:VO_0002289 a rdfs:Class ;
  rdfs:label "Rabies Killed Virus Vaccine-Ehrlichia Risticii Bacterin (USDA: 4905.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002476 , obo:VO_0007748 .

obo:VO_0011323 a rdfs:Class ;
  rdfs:label "Gal/GalNAc lectin" ;
  rdfs:comment "Study tested if vaccination with the E. histolytica Gal/GalNAc lectin could prevent cecal infection in a C3H mouse model of amebic colitis. Vaccination prevented intestinal infection with efficacies of 84 and 100% in the two native lectin trials and 91 and 34% in the two LecA trials.  Results show for the first time that immunization with the Gal/GalNAc lectin can prevent intestinal amebiasis in mice [PubMed: 14741152]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010852 .

obo:VO_0000088 a rdfs:Class ;
  rdfs:label "Pneumovax 23 vaccine" ;
  rdfs:comment "Product Name: Pneumococcal Vaccine, Polyvalent" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000424 , obo:VO_0000556 .

obo:VO_0011532 a rdfs:Class ;
  rdfs:label "Leishmania donovani gp63 protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0001142 .

obo:VO_0001908 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4336.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002349 .

obo:VO_0016149 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015886 .

obo:VO_0002904 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium poxA mutant vaccine" ;
  rdfs:comment "A poxA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0003599 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen" ;
  rdfs:comment "CUI: C4256803" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0017582 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 5.33 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0010881 a rdfs:Class ;
  rdfs:label "Omp1" ;
  rdfs:comment "The MOMP (omp1) DNA immunization induced a non-specific and partial protection in OF1 outbred mice fetuses against challenge with C. abortus [PubMed: 12488563]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:VO_0001384 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae gene" ;
  rdfs:comment "A bacterial gene from Actinobacillus pleuropneumoniae." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0015285 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML [Vaqta]" ;
  rdfs:subClassOf obo:VO_0010745 , obo:VO_0015284 .

obo:VO_0019893 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Flulaval 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019889 , obo:VO_0020340 .

obo:VO_0017542 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017678 .

obo:VO_0011002 a rdfs:Class ;
  rdfs:label "YopD from Y. pestis KIM 10" ;
  rdfs:comment "Modified yopD antigens were able to partially protect immunized mice at various levels against lethal challenge with Y. pestis KIM 1001 strain [PubMed: 18291562]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0000692 a rdfs:Class ;
  rdfs:label "peptide vaccine role" ;
  rdfs:comment "A subunit vaccine role that indicates the vaccine being a peptide vaccine. " ;
  rdfs:subClassOf obo:VO_0000624 .

obo:VO_0015657 a rdfs:Class ;
  rdfs:label "1 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015560 , obo:VO_0015599 .

obo:VO_0016860 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Pur] Box of 2 by Novartis" ;
  rdfs:subClassOf obo:VO_0016808 .

obo:VO_0001373 a rdfs:Class ;
  rdfs:label "immunized by vaccination with a licensed vaccine" ;
  rdfs:comment "an organismal quality that indicates an organism (e.g., human) is immunized against a disease through vaccination with a licensed vaccine." ;
  rdfs:subClassOf obo:VO_0000151 .

obo:VO_0005384 a rdfs:Class ;
  rdfs:label "TRAC478 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:NCBITaxon_12721 a rdfs:Class ;
  rdfs:label "Human immunodeficiency virus" ;
  rdfs:subClassOf obo:NCBITaxon_11646 .

obo:VO_0015579 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Lt Grk]" ;
  rdfs:subClassOf obo:VO_0015496 , obo:VO_0015553 .

obo:VO_0001969 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1187.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0020860 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluarix] Box of 20" ;
  rdfs:subClassOf obo:VO_0020858 , obo:VO_0020885 .

obo:VO_0003284 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0010132 a rdfs:Class ;
  rdfs:label "host pregnancy variable" ;
  rdfs:comment "A variable representing the presence of another developing organism in an animal host" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0020323 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2022-2023 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0000983 , obo:VO_0010428 .

obo:VO_0015939 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015637 , obo:VO_0016036 .

obo:VO_0004464 a rdfs:Class ;
  rdfs:label "Schistosoma mansoni DNA vaccine Sm-p80-pcDNA3 encoding the large subunit of Schistosoma mansoni calpain" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003046 .

obo:VO_0002508 a rdfs:Class ;
  rdfs:label "Salmonella gallinarum vaccine" ;
  rdfs:comment "A bacterial vaccine that protects against infections by  Salmonella enterica subsp. enterica serovar Gallinarum." ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0003436 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0019500 .

obo:VO_0000996 a rdfs:Class ;
  rdfs:label "SpayVac vaccine" ;
  rdfs:comment "A contraceptive vaccine that has proven highly effective in deer and can be used to control populations." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000655 , obo:VO_0000759 .

obo:VO_0002435 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Chlamydia Psittaci Vaccine" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0000573 , obo:VO_0002440 .

obo:VO_0019681 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0019973 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML [Fluarix 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020316 .

obo:VO_0004152 a rdfs:Class ;
  rdfs:label "vP869 vaccine" ;
  rdfs:subClassOf obo:VO_0000123 .

obo:NCBITaxon_5804 a rdfs:Class ;
  rdfs:label "Eimeria maxima" ;
  rdfs:subClassOf obo:NCBITaxon_5800 .

obo:VO_0015617 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0003424 , obo:VO_0015547 .

obo:VO_0003570 a rdfs:Class ;
  rdfs:label "Prevnar 13 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003569 .

obo:OPL_0000256 a rdfs:Class ;
  rdfs:label "oocyst-derived sporozoite stage" ;
  rdfs:comment "A sporozoite stage in some parasite lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000152 .

obo:VO_0002183 a rdfs:Class ;
  rdfs:label "Marek's Disease-Newcastle Disease Serotypes 2 & 3, Live Virus & Live Marek's Disease Vector Vaccine (USDA: 17H1.R2)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002447 , obo:VO_0007748 .

obo:VO_0016243 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015911 .

obo:VO_0004930 a rdfs:Class ;
  rdfs:label "human senior age range at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004927 .

obo:VO_0018724 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0018717 .

obo:VO_0003989 a rdfs:Class ;
  rdfs:label "Adacel 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003988 .

obo:VO_0019479 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.02 MG/ML / tetanus toxoid vaccine, inactivated 0.048 MG/ML Injectable Solution [OmniHIB]" ;
  rdfs:subClassOf obo:VO_0019472 , obo:VO_0019478 .

obo:VO_0016468 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Mtk" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0006048 a rdfs:Class ;
  rdfs:label "respiratory syncytial virus monoclonal antibody (palivizumab) intramuscular" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000753 .

obo:VO_0002757 a rdfs:Class ;
  rdfs:label "fabB/fabF from Plasmodium falciparum" ;
  rdfs:comment "A genetically attenuated parasite (GAP) with a mutation in the FabB/FabF gene is attenuated in mice by arresting in the late liver stage. It also conferred complete protection in mice from challenge with wild type Plasmodium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000172 .

obo:VO_0002877 a rdfs:Class ;
  rdfs:label "Salmonella Gallinarum cpxR/Ion mutant vaccine" ;
  rdfs:comment "A cpxR mutant, in combination with a lon mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ;
  rdfs:subClassOf obo:VO_0002508 .

obo:VO_0017315 a rdfs:Class ;
  rdfs:label "Candida albicans extract / diphtheria toxoid vaccine, inactivated / Glycerin / Proteus mirabilis / Purified Protein Derivative of Tuberculin / tetanus toxin Injectable Solution [Multitest Cmi]" ;
  rdfs:subClassOf obo:VO_0017314 .

obo:VO_0000812 a rdfs:Class ;
  rdfs:label "USA licensed vaccine role" ;
  rdfs:comment "a licensed vaccine role that indicates the vaccine occurs in USA." ;
  rdfs:subClassOf obo:VO_0000630 .

obo:VO_0017734 a rdfs:Class ;
  rdfs:label "2 ML acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017731 , obo:VO_0017765 .

obo:VO_0000925 a rdfs:Class ;
  rdfs:label "Babesia bovis vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0016718 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016694 , obo:VO_0016706 .

obo:VO_0003092 a rdfs:Class ;
  rdfs:label "Orimune vaccine" ;
  rdfs:comment "monovalent vaccine agianst poliomyelitis for infants 6-12 weeks of age, all immunized children up to 18 years of age, and high risk adults." ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0003167 .

obo:VO_0018020 a rdfs:Class ;
  rdfs:label "Poliomyelitis Virus Type 3 (Sabin Strain (Leon 12a1b)) Live Attenuated Oral Vaccine" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0003167 .

obo:VO_0005278 a rdfs:Class ;
  rdfs:label "(H115D)VHL35 Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0011226 a rdfs:Class ;
  rdfs:label "VP7 from Bovine rotavirus" ;
  rdfs:comment "Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system.   Neonates of animals immunized with virus-like particles composed of VP7 assembled on VP6 spherical particles were protected against challenge with the homotypic virus and significantly protected from a heterotypic challenge.  Unassembled VP7 protein provided partial protection against challenge [PubMed: 8382422]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010789 .

obo:VO_0010153 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine SP, protein-based, adjuvanted, B.1.351 strain (VidPrevtyn Beta), Sanofi-GSK" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005264 .

obo:VO_0016918 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix] by GSK" ;
  rdfs:subClassOf obo:VO_0016917 .

obo:DOID_184 a rdfs:Class ;
  rdfs:label "bone cancer"@en ;
  rdfs:comment "A connective tissue cancer that is located_in bone and is characterized by uncontrolled cellular proliferation that destroys normal bone tissue."@en ;
  rdfs:subClassOf obo:DOID_0080001 , obo:DOID_201 .

obo:VO_0018005 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) Injection [Adacel]" ;
  rdfs:subClassOf obo:VO_0018004 .

obo:VO_0010255 a rdfs:Class ;
  rdfs:label "vaccine target variable" ;
  rdfs:comment "A variable representing the vaccine target (pathogen, disease) etc." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0017530 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 2000 IU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017529 .

obo:VO_0010393 a rdfs:Class ;
  rdfs:label "vaccine monovalent role" ;
  rdfs:comment "A vaccine that is designed to immunize against a single antigen or single strain of a pathogen." ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0005346 a rdfs:Class ;
  rdfs:label "COVID-19 DNA vaccine by the University of Hong Kong and Immuno Cure 3 Limited" ;
  rdfs:comment "A SARS-CoV-2 DNA vaccine developed by University of Hong Kong and Immuno Cure 3 Limited" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0000212 a rdfs:Class ;
  rdfs:label "pCI DNA vaccine plasmid" ;
  rdfs:comment "a DNA vaccine plasmid that uses the plasmid labeled pCI." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0004237 a rdfs:Class ;
  rdfs:label "rHA with IL-7 adjuvant vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0015837 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 50 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015609 .

obo:VO_0001323 a rdfs:Class ;
  rdfs:label "amorphous aluminum hydroxyphosphate sulfate adjuvant" ;
  rdfs:comment "An aluminum vaccine adjuvant that is a a proprietary aluminum hydroxyphosphate sulfate formulation that is both physically and functionally distinct from traditional aluminum phosphate and aluminum hydroxide adjuvants." ;
  rdfs:subClassOf obo:VO_0000884 .

obo:VO_0000468 a rdfs:Class ;
  rdfs:label "Mycoplasma gallisepticum bacterin vaccine" ;
  rdfs:comment "a Mycoplasma gallisepticum vaccine that uses bacterin as the protective antigen" ;
  rdfs:subClassOf obo:VO_0000949 , obo:VO_0001077 .

obo:VO_0016138 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0017395 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017670 .

obo:VO_0018068 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 100" ;
  rdfs:subClassOf obo:VO_0018065 , obo:VO_0018076 , obo:VO_0018152 .

obo:VO_0000497 a rdfs:Class ;
  rdfs:label "disorder treatment" ;
  rdfs:comment "Process that leads to treat a disorder that is the physical basis of a disease." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:NCBITaxon_645 a rdfs:Class ;
  rdfs:label "Aeromonas salmonicida" ;
  rdfs:subClassOf obo:NCBITaxon_642 .

obo:VO_0002029 a rdfs:Class ;
  rdfs:label "Mannheimia Haemolytica-Pasteurella Multocida Avirulent Live Culture Vaccine (USDA: 1861.01)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0002446 .

obo:VO_0015008 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML Injection [ActHIB]" ;
  rdfs:subClassOf obo:VO_0015010 .

obo:VO_0003510 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0003507 .

obo:VO_0018499 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 20 by Merck" ;
  rdfs:subClassOf obo:VO_0018465 .

obo:VO_0007522 a rdfs:Class ;
  rdfs:label "electrofusion DC vaccine" ;
  rdfs:comment "A cancer vaccine made with PEG fusions generated from allogeneic dendritic cells and autologous tumor-derived cells with GM-CSF and Il-4. The vaccine is irradiated, frozen, and thawed before being administered to patients with AJCC Stage IV Renal Cell Carcinoma. The vaccine could have and effect on the immune system and cancer." ;
  rdfs:subClassOf obo:VO_0005494 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0020889 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Begripal]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0019965 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Flucelvax 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019945 .

obo:VO_0020286 a rdfs:Class ;
  rdfs:label "varicella-zoster virus vaccine live (Oka-Merck) strain 2700 UNT/ML Injection [Varivax]" ;
  rdfs:subClassOf obo:VO_0000119 , obo:VO_0020285 .

obo:VO_0019159 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010447 .

obo:VO_0003910 a rdfs:Class ;
  rdfs:label "FLUAD 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000362 , obo:VO_0004281 .

obo:VO_0017475 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 12.5 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0002148 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0020543 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Begripal]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020854 .

obo:VO_0015257 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Havpur] Box of 1" ;
  rdfs:subClassOf obo:VO_0015256 , obo:VO_0015259 .

obo:VO_0004292 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pCMV/Hl encoding H1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0003559 a rdfs:Class ;
  rdfs:label "Prevnar 13 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003570 .

obo:VO_0015138 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015133 , obo:VO_0015304 .

obo:VO_0000985 a rdfs:Class ;
  rdfs:label "fowl pox vaccine" ;
  rdfs:comment "a viral vaccine that is used to protect against fowl pox virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000512 .

obo:VO_0003656 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent Pediatric Dose for 6-35 Months of Age 2018-2019 Vaccine 0.25 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003655 .

obo:VO_0004687 a rdfs:Class ;
  rdfs:label "HSVT[VP7/6/2] vaccine" ;
  rdfs:subClassOf obo:VO_0000658 .

obo:VO_0001928 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.26)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002353 .

obo:VO_0018105 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0018104 .

obo:VO_0020373 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Oral Powder" ;
  rdfs:subClassOf obo:VO_0003449 .

obo:VO_0002446 a rdfs:Class ;
  rdfs:label "Mannheimia Haemolytica-Pasteurella Multocida vaccine" ;
  rdfs:subClassOf obo:VO_0000620 , obo:VO_0001466 , obo:VO_0001523 .

obo:VO_0019833 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0003480 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010304 , obo:VO_0010415 .

obo:VO_0002475 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis vaccine" ;
  rdfs:subClassOf obo:VO_0001474 , obo:VO_0001495 , obo:VO_0001505 .

obo:OBI_0600007 a rdfs:Class ;
  rdfs:label "administering substance in vivo"@en ;
  rdfs:comment "A process by which a substance is intentionally given to an organism resulting in exposure of the organism to that substance."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0016509 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Lt Grk] Box of 25 by Gerke" ;
  rdfs:subClassOf obo:VO_0015981 .

obo:VO_0003537 a rdfs:Class ;
  rdfs:label "Varicellovirus vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Varicellovirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000727 .

obo:VO_0018047 a rdfs:Class ;
  rdfs:label "poliomyelitis virus type 1 brunhilde / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett)" ;
  rdfs:subClassOf obo:VO_0000664 , obo:VO_0000712 .

obo:OGG_3000888751 a rdfs:Class ;
  rdfs:label "sigE" ;
  rdfs:comment "Alternative RNA polymerase sigma factor SigE" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0003588 a rdfs:Class ;
  rdfs:label "Fluzone 2016-2017 High-Dose vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003587 .

obo:VO_0002429 a rdfs:Class ;
  rdfs:label "equine EEV and WEV encephalomyelitis-rhinopneumonitis-influenza vaccine-tetanus toxoid" ;
  rdfs:subClassOf obo:VO_0002422 , obo:VO_0002428 .

obo:VO_0000587 a rdfs:Class ;
  rdfs:label "Bordetella vaccine" ;
  rdfs:comment "a bacterial vaccine against infection of Bordetella bacterial infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003532 .

obo:VO_0012388 a rdfs:Class ;
  rdfs:label "Hly" ;
  rdfs:comment "In an attempt to generate a subunit vaccine in this experimental disease model, eukaryotic plasmid DNA expression vectors containing genes encoding either the wild-type or modified forms of recombinant listeriolysin O (hly) were generated and used for genetic vaccination of naive mice. Results of these studies indicate that the intramuscular immunization of mice with specifically designed plasmid DNA constructs encoding recombinant forms of listeriolysin O (hly) stimulates peptide-specific CD8+ immune T cells that exhibit in vitro cytotoxic activity. More importantly, such immunization can provide protective immunity against a subsequent challenge with viable L. monocytogenes [PubMed: 10384131]." ;
  rdfs:subClassOf obo:VO_0012369 .

obo:VO_0018802 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine / L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine / L1 protein, Human papillomavirus type 6 Vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 .

obo:VO_0017851 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.008 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010289 , obo:VO_0010444 .

obo:VO_0001170 a rdfs:Class ;
  rdfs:label "vaccine strain" ;
  rdfs:comment "a vaccine organism that is a specific strain" ;
  rdfs:subClassOf obo:VO_0000506 .

obo:VO_0000775 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum MSP1 from transgenic mice vaccine with Freund's adjuvant" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0005395 a rdfs:Class ;
  rdfs:label "DoCo-Pro-RBD-1 + MF59 vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by the University of Melbourne." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:NCBITaxon_623 a rdfs:Class ;
  rdfs:label "Shigella flexneri" ;
  rdfs:subClassOf obo:NCBITaxon_620 .

obo:VO_0007739 a rdfs:Class ;
  rdfs:label "tumor antigen-sensitized DC vaccine" ;
  rdfs:comment "A cancer vaccine that can be used in combination with Neo-antigen DC vaccine and their sensitized T cells for the treatment of esophageal cancer, advanced malignant melanoma, bladder cancer and colorectal cancer." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0020775 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 CELLS Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020773 , obo:VO_0020806 .

obo:VO_0001464 a rdfs:Class ;
  rdfs:label "carnivora vaccine" ;
  rdfs:comment "Vaccine that used for immunizing carnivora." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001218 .

obo:VO_0020942 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus antigen Nasal Spray [FluMist Quadrivalent]" ;
  rdfs:subClassOf obo:VO_0020941 .

obo:VO_0004040 a rdfs:Class ;
  rdfs:label "Pseudorabies Subunit gI protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000750 .

obo:NCBITaxon_10298 a rdfs:Class ;
  rdfs:label "Human alphaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_10294 .

obo:VO_0001286 a rdfs:Class ;
  rdfs:label "Algammulin vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant that suspension of 1-2um ovoids of immune stimulant gamma inulin (g-IN) in which alum is embedded as a carrier for protein or other anionic antigens." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0019632 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2020 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020490 .

obo:VO_0020792 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 500000000 CFU Injection [Oncotice Bcg] Box of 3" ;
  rdfs:subClassOf obo:VO_0020791 , obo:VO_0020793 .

obo:VO_0018590 a rdfs:Class ;
  rdfs:label "5 ML Anthrax Vaccine Adsorbed 0.1 MG/ML Injectable Suspension [Biothrax] by Emergent Sales And Marketing" ;
  rdfs:subClassOf obo:VO_0018588 , obo:VO_0018589 .

obo:VO_0002290 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae Bacterin (USDA: 4906.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002485 , obo:VO_0007748 .

obo:VO_0007609 a rdfs:Class ;
  rdfs:label "gp100:280-288(288V) peptide vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0002468 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Vaccine-Bordetella Bronchiseptica-Clostridium Perfringens Type C-Erysipelothrix Rhusiopathiae-Escherichia Coli-Pasteurella Multocida Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000620 , obo:VO_0001456 , obo:VO_0002469 .

obo:IDO_0000547 a rdfs:Class ;
  rdfs:label "virulence factor"@en ;
  rdfs:comment "A biological macromolecule produced by a pathogen and that has a virulence factor disposition."@en ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0005495 a rdfs:Class ;
  rdfs:label "sarcoma cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against sarcoma cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0004024 a rdfs:Class ;
  rdfs:label "Treponema pallidum GlpQ protein vaccine" ;
  rdfs:subClassOf obo:VO_0001230 .

obo:VO_0021138 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017618 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] Box of 2" ;
  rdfs:subClassOf obo:VO_0017616 , obo:VO_0017627 .

obo:VO_0000566 a rdfs:Class ;
  rdfs:label "Vibrio vaccine" ;
  rdfs:comment "Vaccine that protects against Vibrio infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0020131 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010289 , obo:VO_0010444 .

obo:VO_0020872 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020897 .

obo:VO_0019800 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003638 .

obo:VO_0005133 a rdfs:Class ;
  rdfs:label "MVvac2-MERS-S(H) vaccine" ;
  rdfs:comment "A MERS recombinant vector vaccine made of live-attenuated measles virus (MV) vaccine encoding the MERS-CoV spike protein (MERS-S)." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0011436 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei subunit LolC protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012175 .

obo:VO_0016383 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 3 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015946 .

obo:VO_0004672 a rdfs:Class ;
  rdfs:label "SL3261-L. donovani vaccine" ;
  rdfs:subClassOf obo:VO_0001142 .

obo:VO_0015094 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015252 .

obo:VO_0015042 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 31 Vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003304 .

obo:VO_0002784 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis mce-2/mce-3 mutant vaccine" ;
  rdfs:comment "A Mce-2 mutant in Mycobacterium tuberculosis is attenuated and provides protection against challenge for mice" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0010959 a rdfs:Class ;
  rdfs:label "RESA" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010771 .

obo:VO_0010719 a rdfs:Class ;
  rdfs:label "Infanrix-hexa vaccine" ;
  rdfs:comment "A combination vaccine that protects infants from diphtheria, tetanus, pertussis (whooping cough), polio, hepatitis B and Haemophilus influenzae type b (Hib)." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000946 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0000351 a rdfs:Class ;
  rdfs:label "Adjumer vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is PCPP salt." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0000539 a rdfs:Class ;
  rdfs:label "equine EEV, VEV and WEV encephalomyelitis-influenza vaccine-tetanus toxoid" ;
  rdfs:subClassOf obo:VO_0000541 , obo:VO_0002422 .

obo:VO_0007009 a rdfs:Class ;
  rdfs:label "Nelipepimut-S Plus GM-CSF Vaccine" ;
  rdfs:comment "A cancer peptide vaccine comprised of a human leukocyte antigen (HLA) A2/A3 restricted HER2/neu (ERBB2) peptide from the extracellular domain of the HER2 protein (E75 peptide) and combined with the immunoadjuvant granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunomodulating and antineoplastic activity. Upon intradermal injection, nelipepimut-S plus GM-CSF vaccine may induce a specific cytotoxic T-lymphocyte (CTL) response against HER2/neu-expressing tumor cell types. HER2/neu, a tumor-associated antigen and a member of the epidermal growth factor receptor family of tyrosine kinases, is overexpressed in various tumor cell types. GM-CSF potentiates the antitumor immune response." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0000383 a rdfs:Class ;
  rdfs:label "vaccine-induced, adjuvant boosted T cell interferon-gramm production" ;
  rdfs:comment "a vaccine-induced T cell interferon-gramm production that results from the addition of a vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000273 .

obo:VO_0000569 a rdfs:Class ;
  rdfs:label "vaccine-induced up-regulated gene expression" ;
  rdfs:subClassOf obo:VO_0000286 .

obo:VO_0017060 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0017049 , obo:VO_0017528 .

obo:VO_0017980 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Menjugate] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017970 .

obo:VO_0017253 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017252 .

obo:NCBITaxon_1903411 a rdfs:Class ;
  rdfs:label "Yersiniaceae" ;
  rdfs:subClassOf obo:NCBITaxon_91347 .

obo:VO_0016699 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 30 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0019927 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Prefilled Syringe [Flucelvax 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019923 , obo:VO_0020328 .

obo:VO_0001481 a rdfs:Class ;
  rdfs:label "Pigeonpox virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Pigeonpox virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000512 .

obo:VO_0003682 a rdfs:Class ;
  rdfs:label "Fluvirin 2016-2017 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003681 .

obo:VO_0004704 a rdfs:Class ;
  rdfs:label "SabRV-SIV vaccine" ;
  rdfs:subClassOf obo:VO_0000751 .

obo:VO_0002717 a rdfs:Class ;
  rdfs:label "UL23 from Gallid herpesvirus 1" ;
  rdfs:comment "A thymidine-kinase mutant is attenuated in chickens and induced protection from challenge with wild type GHV-1" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001435 .

obo:CL_0000232 a rdfs:Class ;
  rdfs:label "erythrocyte" ;
  rdfs:comment "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." ;
  rdfs:subClassOf obo:CL_0000763 .

obo:VO_0005027 a rdfs:Class ;
  rdfs:label "pCMVi-UB DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCMVi-UB.  This plasmid was built from pCMV-5 and contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007027 a rdfs:Class ;
  rdfs:label "NY-ESO-1b peptide vaccine" ;
  rdfs:comment "A recombinant nonapeptide used as an antineoplastic vaccine. NY-ESO-1b peptide vaccine contains the amino acid sequence SLLMWITQC, derived from the cancer-testis tumor antigen (NY-ESO-1), which is expressed on tumor cells of many different types, including melanomas. Vaccination with this peptide vaccine may elicit strong humoral and cellular immune responses to NY-ESO-1-expressing cancers." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0015242 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015237 .

obo:VO_0010465 a rdfs:Class ;
  rdfs:label "correlated profile of immune protection based on population coverage" ;
  rdfs:subClassOf obo:VO_0000857 .

obo:VO_0012392 a rdfs:Class ;
  rdfs:label "FnbA" ;
  rdfs:comment "Mice were immunized with fusion proteins encompassing the fibronectin-binding domain of a staphylococcal fibronectin-binding protein (FnBP-A). Vaccination of mice with recombinant FnBP resulted in significant protection against challenge with S. aureus [PubMed: 7975852]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012355 .

obo:VO_0016355 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:DOID_874 a rdfs:Class ;
  rdfs:label "bacterial pneumonia"@en ;
  rdfs:comment "A pneumonia involving inflammation of the lungs caused by bacteria."@en ;
  rdfs:subClassOf obo:DOID_104 , obo:DOID_850 .

obo:VO_0010347 a rdfs:Class ;
  rdfs:label "Frozen Formulation - Human SerumAlbumin (HSA) - ProQuad vaccine" ;
  rdfs:subClassOf obo:VO_0000091 .

obo:VO_0002696 a rdfs:Class ;
  rdfs:label "yopH from Yersinia pestis" ;
  rdfs:comment "A yopH mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001426 .

obo:VO_0016207 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0004939 a rdfs:Class ;
  rdfs:label "human age 2 to 3 years at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0015333 a rdfs:Class ;
  rdfs:label "Hepatitis A Virus / Salmonella Typhi Inactivated Antigen Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000950 , obo:VO_0001214 , obo:VO_0010438 , obo:VO_0010451 .

obo:VO_0000189 a rdfs:Class ;
  rdfs:label "colony forming unit" ;
  rdfs:comment "A titer measurement of viable bacterial or fungal numbers. Unlike in direct microscopic counts where all cells, dead and living, are counted, CFU measures viable cells. By convenience the results are given as CFU/mL (colony-forming units per milliliter) for water, and CFU/g (colony-forming units per gram) for soil or other porous material." ;
  rdfs:subClassOf obo:VO_0000555 .

obo:VO_0012377 a rdfs:Class ;
  rdfs:label "HspA" ;
  rdfs:comment "Orogastric immunization of mice with recombinant H. pylori HspA proteins protected 80%  of animals from a challenge dose of 10^4 Helicobacter felis bacteria [PubMed: 7604021]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010855 .

obo:OBI_0100026 a rdfs:Class ;
  rdfs:label "organism"@en ;
  rdfs:comment "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0015930 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015635 , obo:VO_0016035 .

obo:VO_0005144 a rdfs:Class ;
  rdfs:label "Ad5-nCoV vaccine" ;
  rdfs:comment "A SARS-CoV-2 vaccine made from a recombinant adinvorius type-5 expressing SARS-CoV-2 S protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005268 .

obo:VO_0018387 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Injectable Solution [Pneumovax II]" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:VO_0005192 a rdfs:Class ;
  rdfs:label "MVC-COV1901 vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine that contains the Spike (S) protein with CpG 1018 and aluminum content as adjuvant." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0011339 a rdfs:Class ;
  rdfs:label "Catalase" ;
  rdfs:comment "Recombinant H. pylori catalase plus CT was used for immunization, and groups of mice were challenged with the Sydney strain of H. pylori. Immunization with recombinant catalase protected a significant proportion (9 of 10) of the mice from H. pylori challenge, indicating that this enzyme should be considered as a candidate for a future vaccine [PubMed: 9353048]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010855 .

obo:VO_0020222 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (BA.4/BA.5) 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0020498 .

obo:VO_0001988 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002361 .

obo:VO_0010142 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, 25 mcg/0.25 mL dose" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0020815 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Pentacel]" ;
  rdfs:subClassOf obo:VO_0000084 , obo:VO_0020832 .

obo:VO_0017642 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [T Medevax]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0017708 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017707 , obo:VO_0017757 .

obo:VO_0020174 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Prefilled Syringe [Ipol]" ;
  rdfs:subClassOf obo:VO_0020171 , obo:VO_0020173 .

obo:VO_0019345 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020173 .

obo:VO_0020583 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Preflucel]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020874 .

obo:VO_0004899 a rdfs:Class ;
  rdfs:label "2012-2013 seasonal trivalent inactivated influenza vaccine (A/California/7/2009 (H1N1), A/Victoria/361/2011 (H3N2), and B/Wisconsin/1/2010)" ;
  rdfs:comment "2012-2013 trivalent seasonal inactivated influenza vaccine 2012-2013  Influenza A virus (A/California/7/2009 (H1N1)), Influenza A virus (A/Victoria/361/2011 (H3N2)), and Influenza B virus (B/Wisconsin/1/2010)" ;
  rdfs:subClassOf obo:VO_0001176 , obo:VO_0001236 .

obo:VO_0015744 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015495 , obo:VO_0015809 .

obo:VO_0017220 a rdfs:Class ;
  rdfs:label "7.5 ML tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017219 , obo:VO_0017472 .

obo:VO_0017804 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 600 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003196 .

obo:OPL_0000353 a rdfs:Class ;
  rdfs:label "Neospora caninum tachyzoite stage" ;
  rdfs:comment "A tachyzoite stage in the Neospora caninum life cycle." ;
  rdfs:subClassOf obo:OPL_0000325 , obo:OPL_0000376 .

obo:DOID_4897 a rdfs:Class ;
  rdfs:label "bile duct carcinoma"@en ;
  rdfs:comment "A bile duct cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells."@en ;
  rdfs:subClassOf obo:DOID_305 , obo:DOID_4606 .

obo:VO_0007633 a rdfs:Class ;
  rdfs:label "long-peptide vaccine and mAb" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0016166 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Europharma" ;
  rdfs:subClassOf obo:VO_0016003 .

obo:VO_0000540 a rdfs:Class ;
  rdfs:label "time of survival of live vaccine inside host" ;
  rdfs:comment "time of survival of live vaccine inside host is a temporal interval during which a live vaccine survives inside a host organism. This entity is related to the process survival of live vaccine inside host." ;
  rdfs:subClassOf obo:BFO_0000038 .

obo:VO_0019879 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Flulaval Quad 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020341 .

obo:VO_0019126 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:VO_0018097 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0018093 , obo:VO_0018231 .

obo:VO_0004522 a rdfs:Class ;
  rdfs:label "Herpes Simplex Virus 2 DNA Vaccine encoding gD" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0017991 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 2000000 CELLS/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 200000 CELLS/ML / poliovirus vaccine inactivated, type 3 (Saukett) 600000 CELLS/ML Injectable Suspension [Polio Sabin-S]" ;
  rdfs:subClassOf obo:VO_0017990 , obo:VO_0018030 .

obo:VO_0020200 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.05 MG/ML / SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (BA.4/BA.5) 0.05 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0017805 a rdfs:Class ;
  rdfs:label "Diphtheria Toxoid-Pertussis-Haemophilus B-Hepatitis B vaccine" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000735 , obo:VO_0000746 , obo:VO_0000765 .

obo:OBI_0000441 a rdfs:Class ;
  rdfs:label "assay objective"@en ;
  rdfs:comment "an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)"@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:VO_0015863 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax] Box of 50" ;
  rdfs:subClassOf obo:VO_0015612 , obo:VO_0015681 , obo:VO_0015991 .

obo:VO_0020867 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Inflexal]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020895 .

obo:VO_0001164 a rdfs:Class ;
  rdfs:label "reduction of colony forming unit" ;
  rdfs:comment "A titer measurement of viable bacterial or fungal numbers. It equals to a reduction of a CFU count from another CFU count. This term is often used as a measurement of a vaccine protection study." ;
  rdfs:subClassOf obo:VO_0000555 .

obo:VO_0017278 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Boostrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0017277 , obo:VO_0017279 .

obo:VO_0017701 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] Box of 5" ;
  rdfs:subClassOf obo:VO_0017696 , obo:VO_0017706 , obo:VO_0017750 .

obo:VO_0003521 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Wisconsin-1-2010-like virus" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003520 , obo:VO_0010415 .

obo:VO_0002345 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea vaccine" ;
  rdfs:subClassOf obo:VO_0000987 , obo:VO_0001501 .

obo:CHEBI_9546 a rdfs:Class ;
  rdfs:label "thimerosal" ;
  rdfs:comment "An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0000207 a rdfs:Class ;
  rdfs:label "vaccine contraindication" ;
  rdfs:comment "A vaccine contraindication is a contraindication that increases the risks of a vaccination. " ;
  rdfs:subClassOf obo:OAE_0000055 .

obo:VO_0003915 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010308 , obo:VO_0010415 .

obo:VO_0018752 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Oral Tablet" ;
  rdfs:subClassOf obo:VO_0018715 .

obo:NCBITaxon_810 a rdfs:Class ;
  rdfs:label "Chlamydia" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:VO_0000796 a rdfs:Class ;
  rdfs:label "human ifng" ;
  rdfs:subClassOf obo:VO_0000791 .

obo:VO_0015180 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0015179 , obo:VO_0015268 .

obo:VO_0000670 a rdfs:Class ;
  rdfs:label "EcSf2a-2 vaccine" ;
  rdfs:comment "A Shigella flexneri vaccine that is an aro-D mutant derivative of EcSf2a-1." ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0017004 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017003 , obo:VO_0017019 , obo:VO_0017490 .

obo:VO_0019294 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluarix 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020318 .

obo:VO_0003155 a rdfs:Class ;
  rdfs:label "rVSV-ZEBOV" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0004660 .

obo:VO_0016517 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0002252 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.46)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002422 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0015804 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 250" ;
  rdfs:subClassOf obo:VO_0015493 .

obo:VO_0017397 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adt Booster] Box of 5" ;
  rdfs:subClassOf obo:VO_0017396 , obo:VO_0017399 .

obo:VO_0000954 a rdfs:Class ;
  rdfs:label "Intervet avian influenza virus vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000461 , obo:VO_0000657 , obo:VO_0003143 .

obo:UBERON_0004121 a rdfs:Class ;
  rdfs:label "ectoderm-derived structure" ;
  rdfs:comment "An anatomical structure that develops (entirely or partially) from the ectoderm." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:VO_0015679 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015563 , obo:VO_0015773 .

obo:VO_0001395 a rdfs:Class ;
  rdfs:label "cocktail vaccine" ;
  rdfs:comment "a vaccine that contains two or more individual vaccines. " ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0007427 a rdfs:Class ;
  rdfs:label "mutant p53 peptide pulsed dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous dendritic cells which have been pulsed with a mutant p53 peptide. Vaccination with mutant p53 peptide pulsed dendritic cells may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing mutant p53, resulting in tumor cell lysis. Many tumor cells overexpress mutant p53 proteins, resulting in the loss of apoptosis regulation and abnormal cell proliferation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0003671 a rdfs:Class ;
  rdfs:label "PedvaxHIB Injectable Product" ;
  rdfs:subClassOf obo:VO_0000083 .

obo:VO_0001691 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 1 & 2 & 3, Live Virus Vaccine (USDA: 16L1.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:NCBITaxon_11270 a rdfs:Class ;
  rdfs:label "Rhabdoviridae" ;
  rdfs:subClassOf obo:NCBITaxon_11157 .

obo:NCBITaxon_12066 a rdfs:Class ;
  rdfs:label "Coxsackievirus" ;
  rdfs:subClassOf obo:NCBITaxon_12059 .

obo:VO_0016789 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension by Sanofi" ;
  rdfs:subClassOf obo:VO_0016733 .

obo:VO_0007536 a rdfs:Class ;
  rdfs:label "Indoleamine 2,3-dioxygenase Peptide vaccine" ;
  rdfs:comment "A peptide vaccine against the immunomodulatory enzyme indoleamine 2,3-dioxygenase (IDO), with potential immunomodulating and antineoplastic activities. Vaccination with indoleamine 2,3-dioxygenase peptide vaccine may activate the immune system to induce an immune response against IDO-expressing cells. This may increase and restore the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, and T-lymphocytes, and may eradicate IDO-expressing tumor cells. IDO, a cytosolic enzyme responsible for tryptophan catabolism and conversion of tryptophan into kynurenine, is overexpressed by a variety of tumor cell types and antigen presenting cells (APCs) and plays an important role in immunosuppression; Tryptophan depletion inhibits T-lymphocyte proliferation and activation, and suppresses the immune system" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0001712 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0019270 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019844 .

obo:VO_0019457 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0018318 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 1" ;
  rdfs:subClassOf obo:VO_0018290 , obo:VO_0018301 , obo:VO_0018323 .

obo:VO_0020883 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Xanaflu] Box of 10" ;
  rdfs:subClassOf obo:VO_0020882 , obo:VO_0020884 .

obo:VO_0015815 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 3" ;
  rdfs:subClassOf obo:VO_0015496 .

obo:VO_0007514 a rdfs:Class ;
  rdfs:label "DC/AML fusion vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous dendritic cells (DCs) fused with autologous acute myeloid leukemia (AML) cells, with potential immunostimulatory and antineoplastic activities. It is generated in vitro by mixing DCs and irradiated AML cells harvested from individual patients, in the presence of polyethylene glycol (PEG), to produce hybrid DC-leukemia fusion cells. The vaccine may elicit a cytotoxic T-lymphocyte (CTL)-mediated antitumor immune response against a broad array of AML-associated antigens, which may lead to AML cell lysis. When dendritic cells and tumor cells are brought together, the dendritic cells can stimulate immune responses against the tumor and, in some cases, cause the tumor to shrink. GM-CSF is a drug that stimulates white blood cells and is given with the DC AML Vaccine in an effort to enhance the effect of the vaccine." ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0003515 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0003514 .

obo:VO_0020453 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0020415 , obo:VO_0020429 .

obo:VO_0003458 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine, Inactivated 50 UNT/ML Injection [Vaqta]" ;
  rdfs:subClassOf obo:VO_0003466 .

obo:VO_0019981 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Injectable Suspension [Fluvirin 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019978 , obo:VO_0020473 .

obo:VO_0002407 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza Vaccine" ;
  rdfs:subClassOf obo:VO_0001526 , obo:VO_0002394 .

obo:VO_0015179 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015267 .

obo:VO_0015220 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015218 .

obo:VO_0005300 a rdfs:Class ;
  rdfs:label "AlT3 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0016704 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0001181 a rdfs:Class ;
  rdfs:label "Vaxsafe MG vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000949 , obo:VO_0001077 .

obo:VO_0004267 a rdfs:Class ;
  rdfs:label "HSV glycoproteins subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012168 .

obo:VO_0019499 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML / typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.025 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019498 .

obo:VO_0000400 a rdfs:Class ;
  rdfs:label "prime-boost vaccine" ;
  rdfs:comment "A vaccine that contains one vaccine for priming and at least one other vaccine for boosting. " ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0007506 a rdfs:Class ;
  rdfs:label "MART-1:26-35(27L) peptide vaccine" ;
  rdfs:comment "Gene name: MLANA" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0003956 a rdfs:Class ;
  rdfs:label "obsolete vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML" .

obo:NCBITaxon_11002 a rdfs:Class ;
  rdfs:label "Infectious pancreatic necrosis virus" ;
  rdfs:subClassOf obo:NCBITaxon_10993 .

obo:VO_0006073 a rdfs:Class ;
  rdfs:label "SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (Anhui Zhifei Longcom Zifivax)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:OPL_0000393 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi sporozoite" ;
  rdfs:comment "A Plasmodium knowlesi in sporozoite stage." ;
  rdfs:subClassOf obo:NCBITaxon_5850 , obo:OPL_0000278 .

obo:VO_0018065 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0018052 , obo:VO_0018150 .

obo:VO_0010706 a rdfs:Class ;
  rdfs:label "Avaxim vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010438 .

obo:VO_0019811 a rdfs:Class ;
  rdfs:label "influenza A virus A/Kansas/14/2017 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Switzerland/3330/2017 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0003262 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003421 .

obo:VO_0015895 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015622 , obo:VO_0015623 , obo:VO_0015730 , obo:VO_0015736 , obo:VO_0016010 .

obo:VO_0004579 a rdfs:Class ;
  rdfs:label "HRSV DNA vaccine DRF-412" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002512 .

obo:OGG_2000224914 a rdfs:Class ;
  rdfs:label "gene of Brucella melitensis bv. 1 str. 16M" ;
  rdfs:comment "A gene of an organism of Brucella melitensis bv. 1 str. 16M" ;
  rdfs:subClassOf obo:OGG_2000001224 .

obo:NCBITaxon_452646 a rdfs:Class ;
  rdfs:label "Neogale vison" ;
  rdfs:subClassOf obo:NCBITaxon_169418 .

obo:VO_0021008 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 19400 PFU [Zostavax]" ;
  rdfs:subClassOf obo:VO_0000124 , obo:VO_0021007 .

obo:VO_0007258 a rdfs:Class ;
  rdfs:label "anti-CEA TCR retroviral vector-transduced autologous peripheral blood lymphocyte vaccine" ;
  rdfs:comment "Autologous human peripheral blood lymphocytes (PBLs), transduced with a retroviral vector encoding both the alpha and beta chains of a T cell receptor (TCR) specific for the carcinoembryonic antigen (CEA), with potential immunostimulating and antineoplastic activities. After transduction, expansion in culture, and reintroduction into the patient, anti-CEA TCR retroviral vector-transduced autologous lymphocytes bind to tumor cells expressing CEA, which may result in cytokine expression, activation and proliferation of T-cells, and a specific cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells. The tumor-associated antigen (TAA) CEA is overexpressed by a variety of cancer cell types, including those of the gastrointestinal tract, lung, and breast." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0017359 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 , obo:VO_0017358 , obo:VO_0017801 .

obo:VO_0003932 a rdfs:Class ;
  rdfs:label "Gardasil Injectable Product" ;
  rdfs:subClassOf obo:VO_0000049 .

obo:VO_0015957 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 100" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015731 , obo:VO_0015737 , obo:VO_0016047 .

obo:VO_0015279 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003431 .

obo:VO_0016196 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015902 .

obo:VO_0001552 a rdfs:Class ;
  rdfs:label "Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0007748 .

obo:VO_0016246 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Fendrix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015914 .

obo:VO_0011458 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum PmpG-1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012176 .

obo:VO_0019182 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020489 .

obo:VO_0001920 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4389.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002352 .

obo:VO_0003780 a rdfs:Class ;
  rdfs:label "Flucelvax 2015-2016 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003779 .

obo:VO_0015639 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites]" ;
  rdfs:subClassOf obo:VO_0015573 , obo:VO_0015669 .

obo:VO_0010904 a rdfs:Class ;
  rdfs:label "BoNT/B" ;
  rdfs:comment "The DNA replicon vaccine (pSCARSBHc) encoding the Hc domain of BoNT/B (BHc) induced better responses and protection against BoNT/B mouse challenge than conventional DNA vaccine.  Recombinant SFV particle VRP-BHc protected mice from high-dose BoNT/B challenge [PubMed: 19712769]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010762 .

obo:VO_0010233 a rdfs:Class ;
  rdfs:label "tuberculin skin test; unspecified formulation" ;
  rdfs:subClassOf obo:NCIT_C85994 .

obo:VO_0001125 a rdfs:Class ;
  rdfs:label "Eimeria maxima vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000906 .

obo:VO_0019584 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0018007 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) Injection [Quadracel]" ;
  rdfs:subClassOf obo:VO_0018004 .

obo:OPL_0000007 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum exflagellated microgametocyte stage" ;
  rdfs:comment "An exflagellated microgametocyte stage in the lifecycle of Plasmodium falciparum that occurs in the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000010 , obo:OPL_0000119 .

obo:VO_0011431 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus DNA vaccine Pomp90A" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001085 .

obo:VO_0003281 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection [Zostavax]" ;
  rdfs:subClassOf obo:VO_0000124 .

obo:VO_0005447 a rdfs:Class ;
  rdfs:label "licensed human rabies immune globulin passive vaccine" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0003634 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016-2017 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003628 .

obo:VO_0000475 a rdfs:Class ;
  rdfs:label "animal Rabies vaccine" ;
  rdfs:comment "a Rabies virus vaccine against Rabies in animal" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0000626 a rdfs:Class ;
  rdfs:label "survival assessment" ;
  rdfs:comment "Survival assessment is an assay that measures the occurence of death events in one or more organisms that are monitored over time." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0003532 a rdfs:Class ;
  rdfs:label "Betaproteobacteria vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003531 .

obo:OPL_0000302 a rdfs:Class ;
  rdfs:label "Plasmodium salivary gland-derived sporozoite stage" ;
  rdfs:comment "A salivary gland-derived sporozoite stage in the Plasmodium lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000253 , obo:OPL_0000300 .

obo:VO_0011518 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus DNA vaccine encoding DnaK" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001085 .

obo:VO_0004995 a rdfs:Class ;
  rdfs:label "UB-612 vaccine" ;
  rdfs:comment "A SARS-CoV-2 S1-RBD-protein based vaccine developed by Vaxxinity" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0015010 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injection [ActHIB]" ;
  rdfs:subClassOf obo:VO_0001214 , obo:VO_0015011 , obo:VO_0020832 .

obo:VO_0016340 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:VO_0017348 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Repevax]" ;
  rdfs:subClassOf obo:VO_0017344 .

obo:VO_0018430 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML Injectable Solution [Pnu-Imune]" ;
  rdfs:subClassOf obo:VO_0018420 .

obo:VO_0020600 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Xanaflu] Box of 10" ;
  rdfs:subClassOf obo:VO_0020599 , obo:VO_0020603 , obo:VO_0020883 .

obo:VO_0018363 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003342 .

obo:VO_0020878 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] Box of 20" ;
  rdfs:subClassOf obo:VO_0020876 , obo:VO_0020885 .

obo:VO_0020426 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0020469 .

obo:VO_0002263 a rdfs:Class ;
  rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.00)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002420 , obo:VO_0007748 .

obo:VO_0015992 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015659 , obo:VO_0015776 .

obo:VO_0018521 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0002334 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002335 .

obo:VO_0000534 a rdfs:Class ;
  rdfs:label "subunit vaccine" ;
  rdfs:comment "A vaccine that is composed of a purified protein(s) or other antigenic determinant(s) from a disease-causing organism. A subunit vaccine does not include the whole organism of a pathogen, so the subunits have less risk of causing adverse reactions." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:VO_0004648 a rdfs:Class ;
  rdfs:label "RB51-SRS2 vaccine" ;
  rdfs:subClassOf obo:VO_0001065 .

obo:VO_0000753 a rdfs:Class ;
  rdfs:label "Respiratory syncytial virus vaccine" ;
  rdfs:comment "A viral vaccine that prevents infection with Respiratory syncytial virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001507 .

obo:VO_0005315 a rdfs:Class ;
  rdfs:label "SCB-2020S vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine by Clover Biopharmaceuticals AUS Pty Ltd that contains the S protein from the B.1.351 variant." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0002950 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 US8 (gE) mutant vaccine" ;
  rdfs:comment "A deletion of BHV-1 gE gene in strain A is considered as a live attenuated vaccine. After challenge, vaccinated calves were protected against disease and virus shedding was reduced" ;
  rdfs:subClassOf obo:VO_0000987 .

obo:VO_0016712 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0016675 , obo:VO_0016688 , obo:VO_0016719 .

obo:NCBITaxon_11768 a rdfs:Class ;
  rdfs:label "Feline leukemia virus" ;
  rdfs:subClassOf obo:NCBITaxon_153135 .

obo:VO_0002097 a rdfs:Class ;
  rdfs:label "Canine Distemper-Hepatitis-Parainfluenza Modified Live Virus Vaccine (USDA: 1381.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002415 , obo:VO_0007748 .

obo:NCBITaxon_1868215 a rdfs:Class ;
  rdfs:label "Orthopneumovirus" ;
  rdfs:subClassOf obo:NCBITaxon_11244 .

obo:VO_0001947 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.28)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0020351 a rdfs:Class ;
  rdfs:label "FluMist Quadrivalent 2019-2020 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000982 , obo:VO_0010420 .

obo:VO_0017854 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.3 MG/ML" ;
  rdfs:subClassOf obo:VO_0003347 .

obo:VO_0010179 a rdfs:Class ;
  rdfs:label "influenza, split virus, trivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0004351 a rdfs:Class ;
  rdfs:label "HIV DNA vaccine VlJns-tPA-gp120" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0021125 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Fluad Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020311 .

obo:VO_0017669 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Haemophilus b vaccine" ;
  rdfs:subClassOf obo:VO_0000662 , obo:VO_0000732 .

obo:VO_0016528 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0005173 a rdfs:Class ;
  rdfs:label "AdimrSC-2f vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine developed by Adimmune Corporation. AdimrSC-2f is a candidate vaccine against COVID-19 developed by Adimmune Corporation (Adimmune). Using the baculovirus-insect cells expression system, the recombinant receptor binding domain (RBD) of SARS-CoV-2 spike (S) protein is amplified and purified. AdimrSC-2f is formulated in the different dosages of Spike (S) protein without/with aluminum content as adjuvant." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0011469 a rdfs:Class ;
  rdfs:label "Eimeria tenella DNA vaccine proIE" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001137 .

obo:VO_0015215 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015206 , obo:VO_0015305 .

obo:VO_0020013 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 158000000 UNT/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 158000000 UNT/ML Nasal Spray [Flumist 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0020012 , obo:VO_0020349 .

obo:VO_0015894 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015622 , obo:VO_0015623 , obo:VO_0015729 , obo:VO_0015735 , obo:VO_0016009 .

obo:VO_0004383 a rdfs:Class ;
  rdfs:label "Ebola virus recombinant vector vaccine Ad-CMVZGP encoding the glycoprotein" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000726 .

obo:VO_0010825 a rdfs:Class ;
  rdfs:label "Theileria annulata protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0017962 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group B vaccine 0.3 MG/ML Injectable Suspension [Bexsero] by GSK" ;
  rdfs:subClassOf obo:VO_0017936 .

obo:VO_0004212 a rdfs:Class ;
  rdfs:label "Canine Parainfluenza Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 47A9.20)" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000455 , obo:VO_0000563 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0001526 , obo:VO_0007748 .

obo:VO_0017497 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:VO_0010746 a rdfs:Class ;
  rdfs:label "Varilrix vaccine" ;
  rdfs:comment "Trade Name: Varilrix" ;
  rdfs:subClassOf obo:VO_0000419 , obo:VO_0000455 , obo:VO_0000714 .

obo:VO_0021165 a rdfs:Class ;
  rdfs:label "varicella virus vaccine" ;
  rdfs:comment "A varicella-zoster virus vaccine, also known as the chickenpox vaccine, that protects against the varicella-zoster virus (VZV) causes chickenpox." ;
  rdfs:subClassOf obo:VO_0000669 .

obo:VO_0020225 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, vector - Ad26 100000000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005267 .

obo:VO_0015231 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain" ;
  rdfs:subClassOf obo:VO_0000950 .

obo:VO_0007525 a rdfs:Class ;
  rdfs:label "MELITAC 12.1 peptide vaccine" ;
  rdfs:comment "A multipeptide cancer vaccine comprised of 12 melanoma peptides restricted by Class I MHC (12MP), plus a tetanus helper peptide" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0018463 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 1" ;
  rdfs:subClassOf obo:VO_0018435 , obo:VO_0018447 .

obo:VO_0001895 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002343 .

obo:VO_0001363 a rdfs:Class ;
  rdfs:label "Clostridium perfringens vaccine" ;
  rdfs:comment "bacterial vaccine that is used to protect against Clostridium perfringens infection" ;
  rdfs:subClassOf obo:VO_0000639 .

obo:VO_0003447 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Delayed Release Oral Capsule" ;
  rdfs:subClassOf obo:VO_0003449 .

obo:VO_0020972 a rdfs:Class ;
  rdfs:label "Influenza Virus Fragmented, Inactivated, Strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain A / Switzerland / 9715293/2013, Nib-88 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0020971 .

obo:OPL_0000267 a rdfs:Class ;
  rdfs:label "Plasmodium gametocyte" ;
  rdfs:comment "A Plasmodium that is located either in the bloodstream of the vertebrate host or midgut of mosquito vector during gametocyte stage. Gametocytes are the precursor cells of the macro- or microgametes" ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0010045 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum MSP2" ;
  rdfs:comment "A MSP2 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0018793 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000943 , obo:VO_0001214 .

obo:VO_0003422 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0004488 a rdfs:Class ;
  rdfs:label "VEE virus DNA vaccine encoding 26S" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001499 .

obo:VO_0000760 a rdfs:Class ;
  rdfs:label "Alzheimer vaccine" ;
  rdfs:comment "A vaccine that prevents or treats Alzheimer disease." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005503 .

obo:VO_0016235 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 50 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015907 .

obo:VO_0004412 a rdfs:Class ;
  rdfs:label "Herpes simplex virus DNA vaccine pCI-gB encoding gB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0003243 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Recombivax]" ;
  rdfs:subClassOf obo:VO_0010737 .

obo:VO_0001192 a rdfs:Class ;
  rdfs:label "mutated gene in vaccine strain datum" ;
  rdfs:comment "A measurement datum that represents a specific mutated gene from a vaccine strain. The mutated can be represented by a described digit. " ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:NCBITaxon_72273 a rdfs:Class ;
  rdfs:label "Thiotrichales" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:VO_0006085 a rdfs:Class ;
  rdfs:label "typhoid vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010451 .

obo:VO_0020505 a rdfs:Class ;
  rdfs:label "rabies virus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:NCBITaxon_12618 a rdfs:Class ;
  rdfs:label "Chicken anemia virus" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:DOID_1579 a rdfs:Class ;
  rdfs:label "respiratory system disease"@en ;
  rdfs:comment "A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm."@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:NCBITaxon_1763 a rdfs:Class ;
  rdfs:label "Mycobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_85007 .

obo:VO_0018177 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution [Priorix] Box of 100" ;
  rdfs:subClassOf obo:VO_0018176 , obo:VO_0018178 .

obo:NCBITaxon_6182 a rdfs:Class ;
  rdfs:label "Schistosoma japonicum" ;
  rdfs:subClassOf obo:NCBITaxon_6181 .

obo:VO_0019144 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020811 .

obo:VO_0019446 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 20 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0005128 a rdfs:Class ;
  rdfs:label "UV-Inactivated SARS + TLR agonist vaccine" ;
  rdfs:comment "A SARS inactivated vaccine made from SARS-CoV inactivated by ultraviolet radiation and a Toll-Like Receptor Agonist Adjuvant is added to prevent eosinophilic immunopathology" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0012183 .

obo:VO_0020511 a rdfs:Class ;
  rdfs:label "hepatitis B virus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0016185 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0005373 a rdfs:Class ;
  rdfs:label "prophylactic vaccination" ;
  rdfs:comment "A vaccination process that involves adding a vaccine into a host prior to disease." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0004849 a rdfs:Class ;
  rdfs:label "Trumenba vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0004847 .

obo:PR_000000001 a rdfs:Class ;
  rdfs:label "protein" ;
  rdfs:comment "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0007690 a rdfs:Class ;
  rdfs:label "MDX-1379 (gp100) melanoma peptide vaccine" ;
  rdfs:comment "A cancer vaccine made up of two peptides that are pieces of a bigger melanoma protein (gp100). These peptides bind to HLA-A2 which is then recognized by T cells. It could be given in combination with MDX-010 (ipilimumab, BMS-734016). MDX-010 (anti-CTLA4) antibodies are designed to keep the immune system running by blocking CTLA-4 from down-regulating T cell activation." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0004606 a rdfs:Class ;
  rdfs:label "Aeromonas hydrophila LSA34 vector vaccine WED/pUTDgap" ;
  rdfs:subClassOf obo:VO_0002505 .

obo:VO_0017261 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Triaxis]" ;
  rdfs:subClassOf obo:VO_0018771 .

obo:VO_0001779 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis Killed Virus Vaccine (USDA: 1525.21)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001486 , obo:VO_0007748 .

obo:VO_0017719 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0017714 , obo:VO_0017726 , obo:VO_0017783 .

obo:VO_0016651 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0017280 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.0105 MG / Bordetella pertussis 0.008 MG / diphtheria toxoid vaccine, inactivated 2 UNT / tetanus toxoid vaccine, inactivated 20 UNT Injection" ;
  rdfs:subClassOf obo:VO_0017230 .

obo:VO_0015924 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015632 , obo:VO_0015691 , obo:VO_0016027 .

obo:VO_0010317 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003501 , obo:VO_0010299 .

obo:VO_0020201 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0020497 .

obo:VO_0011467 a rdfs:Class ;
  rdfs:label "Eimeria maxima Gam82 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001125 .

obo:VO_0016632 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0016564 , obo:VO_0016616 .

obo:VO_0016525 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0016606 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0016594 .

obo:VO_0017433 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.015 MG / Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.25 MG [PedvaxHIB]" ;
  rdfs:subClassOf obo:VO_0000083 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0017672 .

obo:NCBITaxon_444178 a rdfs:Class ;
  rdfs:label "Brucella ovis ATCC 25840" ;
  rdfs:subClassOf obo:NCBITaxon_236 .

obo:VO_0016846 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016794 .

obo:VO_0003581 a rdfs:Class ;
  rdfs:label "Fluzone 2015-2016 High-Dose vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000079 , obo:VO_0015080 .

obo:VO_0010335 a rdfs:Class ;
  rdfs:label "ABRYSVO (STN 125769) vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000753 .

obo:VO_0019103 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010432 .

obo:VO_0017294 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.0936 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017246 .

obo:VO_0020265 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 1000 UNT Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020264 .

obo:VO_0016026 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015667 , obo:VO_0015776 .

obo:VO_0005408 a rdfs:Class ;
  rdfs:label "EG-COVID vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by EyeGene Inc." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0002881 a rdfs:Class ;
  rdfs:label "Salmonella enterica fliC/guaB mutant vaccine" ;
  rdfs:comment "JZ: based on comment,VO:0002890 should be 'Salmonella enterica fliC/guaB mutant vaccine'." ;
  rdfs:subClassOf obo:VO_0002509 .

obo:VO_0003190 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine foreign to USA" ;
  rdfs:comment "A Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine manufactured outside of the U.S" ;
  rdfs:subClassOf obo:VO_0000744 , obo:VO_0003444 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0007451 a rdfs:Class ;
  rdfs:label "human papillomavirus 16/18 L1 virus-like particle/AS04 vaccine" ;
  rdfs:comment "A recombinant, bivalent, human papillomavirus (HPV) vaccine, containing virus-like particles for HPV types 16 and 18 linked to the adjuvant ASO4, with potential immunoprotective and antineoplastic properties. Upon administration, HPV 16/18 L1 virus-like particle/ASO4 vaccine may generate humoral and cellular immunity against HPV types-16 and -18 antigens, thereby preventing cervical infection upon exposure to HPV types 16 and 18. In addition, this agent may stimulate an antitumoral cellular immune response against cervical cancer associated with HPV infection." ;
  rdfs:subClassOf obo:VO_0000667 , obo:VO_0004914 , obo:VO_0007656 .

obo:VO_0002642 a rdfs:Class ;
  rdfs:label "hfq from Salmonella Typhimurium" ;
  rdfs:comment "Oral immunization with the Salmonella hfq deletion mutant efficiently protects mice against subsequent oral challenge with virulent strain of Salmonella Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0016068 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015865 .

obo:VO_0016849 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 50 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016797 .

obo:VO_0005184 a rdfs:Class ;
  rdfs:label "COVID-19 aAPC vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant vector vaccine employing the lentiviral vector system and developed by Shenzhen Geno-Immune Medical Institute." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0015884 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 50" ;
  rdfs:subClassOf obo:VO_0015618 , obo:VO_0016006 .

obo:VO_0019315 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluvirin 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020355 .

obo:VO_0011027 a rdfs:Class ;
  rdfs:label "12D3" ;
  rdfs:comment "Crude extracts of Babesia bovis parasites were systematically fractionated and tested in numerous sequential vaccination/challenge experiments in adult cattle.  Two of these, GST-12D3 and GST-11C5, when used in combination were almost as protective as has been previously shown for the commercially available live attenuated vaccine [PubMed: 1441189]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010827 .

obo:VO_0002795 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis sigE mutant vaccine" ;
  rdfs:comment "A sigE mutant is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis, more so than the existing vaccine BCG" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:NCBITaxon_38170 a rdfs:Class ;
  rdfs:label "Avian orthoreovirus" ;
  rdfs:subClassOf obo:NCBITaxon_2732541 .

obo:VO_0000577 a rdfs:Class ;
  rdfs:label "peptide vaccine" ;
  rdfs:comment "A subunit vaccine that uses small peptide(s) as immunoepitopes. " ;
  rdfs:subClassOf obo:VO_0000534 .

obo:VO_0018423 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II]" ;
  rdfs:subClassOf obo:VO_0018384 , obo:VO_0018387 .

obo:VO_0011044 a rdfs:Class ;
  rdfs:label "CadF" ;
  rdfs:comment "Chitosan-DNA vaccines were prepared by embedding pcDNA3.1(+)-cadF and pcDNA3.1(+)-peblA with chitosan respectively.  The mice immunized with chitosan-DNA vaccines have generated high levels of IgA and IgG from the sera and IgA from the intestinal secretions and the P/N value went up to 20.58, 30.13 and 6.87 respectively.  The chitosan-DNA vaccines induced strongest level of protection in BALB/c mice against challenge with C. jejuni HS:19 strain and the protective efficacies was 93.70 [PubMed: 18206008]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010765 .

obo:VO_0007511 a rdfs:Class ;
  rdfs:label "chimeric exosomal tumor vaccine" ;
  rdfs:comment "A cancer vaccine prepared as tumor cells are isolated from the lesion site of patients with recurrent or metastatic bladder cancer, and dendritic cells or macrophages are isolated from peripheral blood. The vaccine activates an immune response and the microenvironment of bladder cancer lesions, and improves the anti-recurrence treatment effect of bladder cancer. " ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0018150 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0018142 , obo:VO_0018143 , obo:VO_0018183 .

obo:VO_0000356 a rdfs:Class ;
  rdfs:label "pME18100 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001016 a rdfs:Class ;
  rdfs:label "Vectormune FP-ND vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001222 .

obo:OBI_0000274 a rdfs:Class ;
  rdfs:label "adding a material entity into a target"@en ;
  rdfs:comment "is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'."@en ;
  rdfs:subClassOf obo:OBI_0000652 .

obo:VO_0003234 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection" .

obo:VO_0005167 a rdfs:Class ;
  rdfs:label "Chinese Academy of Medical Sciences COVID-19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated whole virus vaccine that is developed by the Chinese Academy of Medical Sciences ." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0018914 a rdfs:Class ;
  rdfs:label "influenza B virus B/Austria/1359417/2021 antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0016797 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0016722 , obo:VO_0016739 , obo:VO_0016824 .

obo:VO_0020486 a rdfs:Class ;
  rdfs:label "Fluzone Intradermal 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003440 , obo:VO_0010416 .

obo:VO_0006098 a rdfs:Class ;
  rdfs:label "2G053 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant, a small molecule TLR agonist that drives a mixed Th1/Th2 response." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0003982 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.02 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Daptacel]" ;
  rdfs:subClassOf obo:VO_0000029 , obo:VO_0001217 .

obo:VO_0004514 a rdfs:Class ;
  rdfs:label "DNA vaccine expressing the E2 protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001012 .

obo:VO_0015478 a rdfs:Class ;
  rdfs:label "Leishmania protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0001873 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calicivirus Modified Live Virus Vaccine (USDA: 16C1.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001220 , obo:VO_0002440 , obo:VO_0007748 .

obo:VO_0016496 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015979 .

obo:VO_0017177 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] Box of 50 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017176 .

obo:VO_0016592 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Adult] Box of 1" ;
  rdfs:subClassOf obo:VO_0016581 , obo:VO_0016597 .

obo:NCBITaxon_5741 a rdfs:Class ;
  rdfs:label "Giardia intestinalis" ;
  rdfs:subClassOf obo:NCBITaxon_2611341 .

obo:VO_0019288 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003579 .

obo:VO_0016641 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by A+S Unicare" ;
  rdfs:subClassOf obo:VO_0016622 .

obo:VO_0003254 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 9N vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0015204 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015282 , obo:VO_0019362 .

obo:VO_0015710 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 50" ;
  rdfs:subClassOf obo:VO_0015570 , obo:VO_0015793 .

obo:VO_0017275 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 , obo:VO_0018775 .

obo:VO_0017561 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0017550 , obo:VO_0017555 .

obo:VO_0010162 a rdfs:Class ;
  rdfs:label "historical diphtheria and tetanus toxoids and acellular pertussis, poliovirus, Haemophilus b conjugate and hepatitis B (recombinant) vaccine." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000942 .

obo:VO_0019246 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Fluad Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020311 .

obo:VO_0002558 a rdfs:Class ;
  rdfs:label "dnt from Bordetella pertussis" ;
  rdfs:comment "A live attenuated B. pertussis vaccine strain BPZE1, developed by deleting dnt gene, protects mice upon a single intranasal administration" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001409 .

obo:VO_0011074 a rdfs:Class ;
  rdfs:label "WbtI" ;
  rdfs:comment "Immunization with WbtI(G191V) protected mice against a relatively low-dose intraperitoneal challenge with LVS (F. tularensis subspecies holarctica live vaccine strain), but was less protective against a high-dose challenge [PubMed: 17768257]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:NCBITaxon_11051 a rdfs:Class ;
  rdfs:label "Flavivirus" ;
  rdfs:subClassOf obo:NCBITaxon_11050 .

obo:VO_0003674 a rdfs:Class ;
  rdfs:label "vaccine vector" ;
  rdfs:comment "Vaccine component that is used to deliver genetic code into the cells to produce antigen. " ;
  rdfs:subClassOf obo:VO_0000179 .

obo:VO_0016297 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Mtk" ;
  rdfs:subClassOf obo:VO_0016027 .

obo:VO_0020275 a rdfs:Class ;
  rdfs:label "obsolete typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution" .

obo:VO_0002975 a rdfs:Class ;
  rdfs:label "obsolete Herpes simplex virus type 1 DNA vaccine encoding GE" ;
  rdfs:comment "An HSV-1 gE (Us8) deletion strain, NS-gEnull, was used as a live attenuated vaccine. After HSV-1 challenge, latent virus was recovered by DRG explant cocultures from <10% of vaccinated mice compared with 100% of mock-vaccinated mice" .

obo:VO_0020973 a rdfs:Class ;
  rdfs:label "Influenza Virus Fragmented, Inactivated, Strain B / Phuket / 3073/2013" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0010305 , obo:VO_0010415 .

obo:VO_0002803 a rdfs:Class ;
  rdfs:label "Bordetella bronchiseptica bscN and cyaA double mutant vaccine" ;
  rdfs:comment "A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 x 105 CFU of RB50, the B. Bronchiseptica parent strain" ;
  rdfs:subClassOf obo:VO_0000394 .

obo:VO_0002598 a rdfs:Class ;
  rdfs:label "iglC from Francisella tularensis" ;
  rdfs:comment "An iglC mutant is highly attenuated in mice. Inoculated mice were challenged 30 days later with wild type F. tularensis and were highly protected" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0011249 a rdfs:Class ;
  rdfs:label "GII" ;
  rdfs:comment "A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 was administered to pigs to determine if it would have a greater protective effect than a vector containing the gene for gp50 alone. Both NYVAC vectors protected pigs similarly from virulent pseudorabies virus challenge [PubMed: 8904669]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010800 .

obo:VO_0001802 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome Reproductive Form, Modified Live Virus Vaccine (USDA: 19Q1.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001511 , obo:VO_0007748 .

obo:VO_0000719 a rdfs:Class ;
  rdfs:label "RNA vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a RNA vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0017291 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017246 .

obo:VO_0016343 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:VO_0000809 a rdfs:Class ;
  rdfs:label "vaccination coverage" ;
  rdfs:comment "A measure datum that measures the coverage of vaccination in a specific area during a specific time period." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0018447 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 1" ;
  rdfs:subClassOf obo:VO_0018425 .

obo:VO_0005231 a rdfs:Class ;
  rdfs:label "COVIGEN vaccine" ;
  rdfs:comment "A SARS-CoV-2 DNA vaccine manufactured by University of Sydney, Bionet Co., and Technovalia" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0007399 a rdfs:Class ;
  rdfs:label "Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor receptor 2 (HER2) with potential antineoplastic activity. Upon administration, modified vaccinia Ankara (Bavarian Nordic)-HER2 vaccine may stimulate the host immune system to mount humoral and cytotoxic T lymphocyte responses against HER2-expressing tumor cells, resulting in tumor cell lysis. HER2, also known as ErbB-2, is a tyrosine kinase growth factor receptor and a member of the epidermal growth factor receptor family; it plays a significant role in the pathogenesis of some breast cancers" ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0020429 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0020469 .

obo:VO_0003850 a rdfs:Class ;
  rdfs:label "Typhim VI Injectable Product" ;
  rdfs:subClassOf obo:VO_0000104 .

obo:DOID_850 a rdfs:Class ;
  rdfs:label "lung disease"@en ;
  rdfs:comment "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide."@en ;
  rdfs:subClassOf obo:DOID_1579 .

obo:VO_0016478 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0001932 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4560.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002354 .

obo:VO_0000536 a rdfs:Class ;
  rdfs:label "Ag85B and ESAT-6 fusion protein vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0017148 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017147 .

obo:PATO_0002146 a rdfs:Class ;
  rdfs:label "virulence" ;
  rdfs:comment "A quality inhering in a bearer by virtue of the severity of infectious disease caused by the bearer in a target organism." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:VO_0017040 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017032 , obo:VO_0017047 , obo:VO_0017511 .

obo:VO_0007370 a rdfs:Class ;
  rdfs:label "Dendritic Cell-CEA Peptide Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of dendritic cells harvested from a patient with cancer and pulsed or transduced with a peptide fragment of carcinoembryonic antigen (CEA), a tumor-associated antigen expressed by a wide range of cancers. When the altered dendritic cells are returned to the patient, they may stimulate the host immune system to mount a cytotoxic T-lymphocyte immune response against tumor cells expressing CEA." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0007666 a rdfs:Class ;
  rdfs:label "gp100 mature dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine using dendritic cells (a kind of white blood cell) as a vaccine could stimulate your own immune system to react to your melanoma cells. Autologous dendritic cells are pulsed with 2 gp100 melanoma peptides (G209-2M and G280-9V) plus up to an additional 10 unique melanoma tumor-specific peptides. Patients also receive cyclophosphamide 300mg/m2 IV in order to deplete regulatory T cells." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0004560 a rdfs:Class ;
  rdfs:label "Helicobacter pylori DNA vaccine pcDNA3.2-hspA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012181 .

obo:VO_0010306 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003498 , obo:VO_0010297 .

obo:VO_0015114 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015111 .

obo:VO_0011103 a rdfs:Class ;
  rdfs:label "UL44 from Herpes simplex virus type 1 and 2" ;
  rdfs:comment "Protection against a lethal intraperitoneal challenge of HSV-1 (5 x 10(4) pfu) with gC (UL44) or gE plasmid vaccination could be demonstrated if the inoculating dose of DNA was 250 microg.  All mice immunized with vaccinia recombinants expressing either gC or gE survived HSV-1 challenge [PubMed: 9728527]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010834 .

obo:VO_0005112 a rdfs:Class ;
  rdfs:label "Inactivated whole MERS-CoV (IV) vaccine with CpG and Alum" ;
  rdfs:comment "A MERS inactivated whole virus vaccine that has a combined adjuvant that has a combined adjuvant of aluminum hydroxide and CpG oligodeoxynucleotides." ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0004900 .

obo:VO_0010238 a rdfs:Class ;
  rdfs:label "challenge admistration route" ;
  rdfs:comment "A variable representing the administration route of the pathogen challenge" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0015057 a rdfs:Class ;
  rdfs:label "Mumps Virus Vaccine Live, Jeryl Lynn Strain 40000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0015056 .

obo:VO_0000470 a rdfs:Class ;
  rdfs:label "autogenous poulty bacterin vaccine" ;
  rdfs:comment "an autogenous bacterin vaccine that is prepared for poultry use. " ;
  rdfs:subClassOf obo:VO_0000469 .

obo:VO_0016662 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by A+S Unicare" ;
  rdfs:subClassOf obo:VO_0016626 .

obo:VO_0001204 a rdfs:Class ;
  rdfs:label "CFU per spleen" ;
  rdfs:comment "A colony forming unit (CFU) from the sample of mouse spleen." ;
  rdfs:subClassOf obo:VO_0000189 .

obo:VO_0001590 a rdfs:Class ;
  rdfs:label "avian influenza H2N2 Subtype, Killed Virus Vaccine (USDA: 1057.H2)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0016035 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0003422 .

obo:VO_0003223 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 19A vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0021110 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020495 .

obo:VO_0000942 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Haemophilus b vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010437 .

obo:VO_0010269 a rdfs:Class ;
  rdfs:label "host pathogen exposure datum" ;
  rdfs:comment "A measurment datum that  records the presence of a prior infection or immune memory to a pathogen." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0000396 a rdfs:Class ;
  rdfs:label "licensed rabbit vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000363 .

obo:VO_0015587 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Fendrix]" ;
  rdfs:subClassOf obo:VO_0015499 , obo:VO_0015546 .

obo:VO_0016427 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 3 by Mtk" ;
  rdfs:subClassOf obo:VO_0015972 .

obo:VO_0017653 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0003410 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injectable Product" ;
  rdfs:subClassOf obo:VO_0003408 , obo:VO_0010437 .

obo:VO_0001158 a rdfs:Class ;
  rdfs:label "Porcilis APP vaccine" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001130 .

obo:VO_0000179 a rdfs:Class ;
  rdfs:label "vaccine component" ;
  rdfs:comment "a processed material that is output of the vaccine preparation and part of a vaccine." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0017529 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 2000 IU/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0016532 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0004441 a rdfs:Class ;
  rdfs:label "Melanoma recombinant vector vaccine rVVmTRP-1 encoding TRP-1" ;
  rdfs:comment "Gene name: TRP-1" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0005104 a rdfs:Class ;
  rdfs:label "Recombinant SARS spike polypeptide vaccine" ;
  rdfs:comment "A SARS DNA vaccine that is made from  intraperitoneal recombinant spike polypeptide generated by amplififying gene encoding amino acids residues 14-667 of S protein that was cloned BamHI and KpnI sites of vector pQE-31 that was generated by Escherichia coli" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000484 , obo:VO_0012183 .

obo:VO_0005083 a rdfs:Class ;
  rdfs:label "CIGB-669 vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine based on recombinant RBD subunits manufactured by the Center for Genetic Engineering and Biotechnology (CIGB)." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0015914 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Fendrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015628 , obo:VO_0015767 .

obo:VO_0019886 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0017949 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec] Box of 1" ;
  rdfs:subClassOf obo:VO_0017904 .

obo:VO_0016182 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0017452 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide 0.02 MG/ML / tetanus toxoid vaccine, inactivated 0.04 MG/ML [Neisvac C]" ;
  rdfs:subClassOf obo:VO_0017451 .

obo:VO_0018256 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML [Rabipur]" ;
  rdfs:subClassOf obo:VO_0003863 .

obo:OBI_0000571 a rdfs:Class ;
  rdfs:label "manufacturer role" ;
  rdfs:comment "Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0015495 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0010711 , obo:VO_0015494 .

obo:VO_0003592 a rdfs:Class ;
  rdfs:label "Fluzone 2017-2018 high-dose vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000079 , obo:VO_0003589 .

obo:VO_0002583 a rdfs:Class ;
  rdfs:label "esrB from Edwardsiella tarda" ;
  rdfs:comment "An esrB mutant is highly attenuated in fish (turbot), with an LD50 of 10(8.1)cfu/fish. Vaccination with this mutant elicited significant protection from wild type E. tarda" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001413 .

obo:VO_0015322 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0000950 , obo:VO_0001214 .

obo:VO_0016015 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0003425 .

obo:VO_0004791 a rdfs:Class ;
  rdfs:label "rBCGMSP1-15 vaccine" ;
  rdfs:subClassOf obo:VO_0000761 .

obo:VO_0019312 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.12 MG/ML Prefilled Syringe [Fluzone High-Dose 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0010418 , obo:VO_0019311 .

obo:VO_0003663 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010317 , obo:VO_0010415 .

obo:VO_0002635 a rdfs:Class ;
  rdfs:label "guaA from Salmonella Typhimurium" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0001457 a rdfs:Class ;
  rdfs:label "Trichomonas foetus vaccine" ;
  rdfs:comment "protozoan vaccine that is used to protect against Tritrichomonas suis infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0000266 a rdfs:Class ;
  rdfs:label "fungal disease" ;
  rdfs:subClassOf obo:DOID_4 .

obo:VO_0016852 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016800 .

obo:VO_0019846 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003913 , obo:VO_0019844 .

obo:VO_0016587 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Adult]" ;
  rdfs:subClassOf obo:VO_0016581 , obo:VO_0016590 .

obo:VO_0000737 a rdfs:Class ;
  rdfs:label "Measles-Mumps-Rubella-Varicella vaccine" ;
  rdfs:comment "A Measles-Mumps-Rubella vaccine that also protects against Varicella." ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 , obo:VO_0003537 .

obo:VO_0017015 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 20 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0017014 .

obo:VO_0003779 a rdfs:Class ;
  rdfs:label "Flucelvax 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000980 .

obo:VO_0002921 a rdfs:Class ;
  rdfs:label "obsolete S. sonnei strain WRSS1" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" .

obo:VO_0000667 a rdfs:Class ;
  rdfs:label "human papillomavirus vaccine" ;
  rdfs:comment "a vaccine against human papillomavirus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003538 .

obo:VO_0018291 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabivac]" ;
  rdfs:subClassOf obo:VO_0018277 , obo:VO_0018295 .

obo:VO_0019891 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Afluria 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019889 , obo:VO_0020302 .

obo:VO_0003382 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003381 , obo:VO_0018809 .

obo:VO_0018605 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 2040000 UNT" ;
  rdfs:subClassOf obo:VO_0004820 .

obo:DOID_684 a rdfs:Class ;
  rdfs:label "hepatocellular carcinoma"@en ;
  rdfs:comment "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver."@en ;
  rdfs:subClassOf obo:DOID_686 .

obo:VO_0018666 a rdfs:Class ;
  rdfs:label "Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML Injectable Solution [Mumpsvax]" ;
  rdfs:subClassOf obo:VO_0018664 , obo:VO_0018665 , obo:VO_0020140 .

obo:VO_0010858 a rdfs:Class ;
  rdfs:label "EBOV GP" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0004504 a rdfs:Class ;
  rdfs:label "avian influenza DNA vaccine pCMV-M" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000461 .

obo:VO_0010996 a rdfs:Class ;
  rdfs:label "IpaD" ;
  rdfs:comment "The invasiveness and virulence of Shigella spp. are largely due to the expression of plasmid-encoded virulence factors, among which are the invasion plasmid antigens (IpaB, IpaC, and IpaD). Recent observations have indicated that the Ipa proteins (IpaB, IpaC, and possibly IpaD) form a multiprotein complex capable of inducing the phagocytic event which internalizes the bacterium.  Researchers isolated a complex of invasins and LPS from water-extractable antigens of virulent shigellae.  Western blot analysis of the complex indicates that all of the major virulence antigens of Shigella, including IpaB, IpaC, and IpaD, and LPS are components of this macromolecular complex.  Guinea pigs (keratoconjunctivitis model) or mice (lethal lung model) immunized intranasally with purivied invasin complex (invaplex) on days 0, 14, and 28 and challenged 3 weeks later with virulent shigellae were protected from disease (P<0.01 for both animal models) [PubMed: 11083774]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010777 .

obo:VO_0002922 a rdfs:Class ;
  rdfs:label "Shigella flexneri strain Sfl 124 vaccine" ;
  rdfs:comment "An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0020420 a rdfs:Class ;
  rdfs:label "obsolete Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1" .

obo:VO_0005263 a rdfs:Class ;
  rdfs:label "CoV2-OGEN1 vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine that is orally administered and manufactured by Syneos Health" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0015162 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0020114 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain / mumps virus vaccine live, Jeryl Lynn strain / rubella virus vaccine live (Wistar RA 27-3 strain) Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0016485 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0001110 a rdfs:Class ;
  rdfs:label "Fecundin vaccine" ;
  rdfs:comment "a fertility vaccine that enhance fertility in sheep." ;
  rdfs:subClassOf obo:VO_0000372 , obo:VO_0000455 , obo:VO_0000503 .

obo:VO_0018303 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabivac] Box of 1" ;
  rdfs:subClassOf obo:VO_0018277 , obo:VO_0018310 .

obo:VO_0000077 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis vaccine" ;
  rdfs:comment "A Mycobacterium vaccine that protects against Mycobacterium tuberculosis." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000592 .

obo:VO_0011110 a rdfs:Class ;
  rdfs:label "NP from Influenza B virus" ;
  rdfs:comment "BALB/c mice were immunized intranasally with an adjuvant (cholera toxin B subunit containing 0.2% of the whole toxin)-combined with A or B virus recombinant NP. The NP-immune mice, when challenged intranasally with a sublethal dose of the virus 3 wk after immunization, had accelerated virus clearance from the nasal site in both an influenza type-specific and a nonspecific manner, as shown by the protection from high morbidity from the second day after challenge [PubMed: 8621928]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0002305 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002480 .

obo:VO_0010450 a rdfs:Class ;
  rdfs:label "licensed human rubella virus vaccine" ;
  rdfs:comment "Rubella virus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0010637 .

obo:VO_0001005 a rdfs:Class ;
  rdfs:label "pSecTag2 C DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pSecTag2 C.  This plasmid is 5167 base pairs long, has a CMV promoter and ampicillin and zeocin resistance genes." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015852 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] by Merck" ;
  rdfs:subClassOf obo:VO_0015647 .

obo:VO_0016801 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] Box of 20" ;
  rdfs:subClassOf obo:VO_0016725 , obo:VO_0016743 , obo:VO_0016821 .

obo:VO_0020983 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, strain A / Victoria / 361/2011 H3N2 - Derived Strain Used Ivr-165 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0020982 .

obo:VO_0010749 a rdfs:Class ;
  rdfs:label "Vivotif vaccine (Canada)" ;
  rdfs:subClassOf obo:VO_0003353 .

obo:VO_0017029 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension [T-Immun Immuno] by Baxter" ;
  rdfs:subClassOf obo:VO_0017026 .

obo:VO_0002569 a rdfs:Class ;
  rdfs:label "pgm from B. abortus" ;
  rdfs:comment "A pgm mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000793 .

obo:VO_0011182 a rdfs:Class ;
  rdfs:label "TBP2" ;
  rdfs:comment "Mice immunized with purified Tbp2 survived a lethal challenge to a similar degree as animals immunized with the Tbp1-Tbp2 complex, demonstrating that Tbp2 played an important role in the protective activity observed with the complex, eliciting antibodies that are not only bactericidal but also inhibitory for meningococcal growth [PubMed: 7868259]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0017101 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017096 .

obo:VO_0020822 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Adacel]" ;
  rdfs:subClassOf obo:VO_0000005 .

obo:OBI_0302893 a rdfs:Class ;
  rdfs:label "storage"@en ;
  rdfs:comment "A planned process with the objective to preserve and protect material entities by placing them in an identified location which may have a controlled environment."@en ;
  rdfs:subClassOf obo:OBI_0000838 .

obo:VO_0018864 a rdfs:Class ;
  rdfs:label "influenza A virus A/Idaho/07/2018 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0011350 a rdfs:Class ;
  rdfs:label "Leishmania infantum H2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012159 .

obo:VO_0004430 a rdfs:Class ;
  rdfs:label "B16 melanoma DNA vaccine pCMV-hTRP-1 encoding TRP-1" ;
  rdfs:comment "Gene name: TYRP1" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:NCBITaxon_521 a rdfs:Class ;
  rdfs:label "Bordetella avium" ;
  rdfs:subClassOf obo:NCBITaxon_517 .

obo:VO_0015292 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015290 .

obo:VO_0015758 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Fendrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015580 , obo:VO_0015817 .

obo:VO_0001514 a rdfs:Class ;
  rdfs:label "avian pneumovirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against avian pneumovirus (avian metapneumovirus) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 , obo:VO_0001461 .

obo:VO_0005178 a rdfs:Class ;
  rdfs:label "adenovirus serotype 26 vaccine vector" ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0003702 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2016-2017 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003701 .

obo:VO_0003221 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 17F vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0012367 a rdfs:Class ;
  rdfs:label "MPT64" ;
  rdfs:comment """DNA vaccines encoding secreted proteins Ag85B and MPT64 protect mice from the tuberculosis H37Rv strain [PubMed: 15498274]. 
*Note* MPT64 in combination with Ag85B was protective, DNA vaccine of just MPT64 was mildly protective in mice.""" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0020572 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Inflexal] by Crucell" ;
  rdfs:subClassOf obo:VO_0020569 .

obo:VO_0002370 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0002371 .

obo:VO_0007411 a rdfs:Class ;
  rdfs:label "methanol extraction residue of BCG" ;
  rdfs:comment "A cell wall fraction of bacillus Calmette-Guerin (BCG) obtained by menthol extraction with immunomodulating properties and potential use in cancer immunotherapy." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0004122 a rdfs:Class ;
  rdfs:label "BCG auxotroph expressing HIV-1 clade immunogen vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0020742 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 120 MG" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017681 .

obo:OBI_0000014 a rdfs:Class ;
  rdfs:label "regulator role"@en ;
  rdfs:comment "a regulatory role involved with making and/or enforcing relevant legislation and governmental orders"@en ;
  rdfs:subClassOf obo:OBI_0000017 .

obo:VO_0020554 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluarix] Box of 20" ;
  rdfs:subClassOf obo:VO_0020551 , obo:VO_0020606 , obo:VO_0020860 .

obo:VO_0010870 a rdfs:Class ;
  rdfs:label "Caf1 from Y. pestis biovar Microtus str. 91001" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:CHEBI_16670 a rdfs:Class ;
  rdfs:label "peptide" ;
  rdfs:comment "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0010038 a rdfs:Class ;
  rdfs:label "live attenuated vaccine role" ;
  rdfs:comment "Vaccine role that is characteristic of a live attenuated vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0004436 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine SINCp c-muMUC18 encoding MCAM/MUC18" ;
  rdfs:comment "Gene name: Mcam" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0015874 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 20" ;
  rdfs:subClassOf obo:VO_0015615 , obo:VO_0015696 , obo:VO_0015999 .

obo:VO_0007503 a rdfs:Class ;
  rdfs:label "MART-1 Fowlpox vaccine" ;
  rdfs:comment "A synthetic cancer vaccine derived from a melanoma-associated antigen, MART-1. Antigenic peptides derived from MART-1 are recognized by CD8+ T lymphocytes and have been used to immunize patients with advanced melanomas; prolonged immunization may result in a reduction in tumor size. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0015484 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis Group B Membrane vesicles External Omv" ;
  rdfs:subClassOf obo:VO_0003960 .

obo:VO_0001824 a rdfs:Class ;
  rdfs:label "Hemorrhagic Enteritis Live Virus Vaccine (USDA: 17E1.20)" ;
  rdfs:subClassOf obo:VO_0000125 , obo:VO_0000455 , obo:VO_0001516 , obo:VO_0007748 .

obo:VO_0003504 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0001215 a rdfs:Class ;
  rdfs:label "Vaxstrate vaccine" ;
  rdfs:comment "an anti-reproductive vaccine for cattle. The vaccine is based on the established principle that antibodies to the hypothalamic releasing hormone, gonadotrophin releasing hormone (GnRH) block the action of GnRH on pituitary secretion of luteinizing hormone and follicle stimulating hormone, leading to gonadal atrophy in mammals. The vaccine comprises an immunogenic GnRH:ovalbumin conjugate formulated in a novel double adjuvant system and is administered in a two-dose treatment regimen. " ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000643 , obo:VO_0000759 .

obo:VO_0002396 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2 Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0002397 .

obo:VO_0017815 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y / tetanus toxoid vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000640 , obo:VO_0001214 , obo:VO_0017812 .

obo:VO_0017816 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide / tetanus toxoid vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000561 , obo:VO_0000640 , obo:VO_0001214 .

obo:VO_0015880 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 50" ;
  rdfs:subClassOf obo:VO_0015617 , obo:VO_0016006 .

obo:VO_0016543 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015984 .

obo:VO_0011097 a rdfs:Class ;
  rdfs:label "UL27 from Herpes simplex virus type 2" ;
  rdfs:comment "The present study evaluated the modulatory functions of salbutamol co-administered with DNA vaccine expressing gB (UL27) of herpes simplex virus (HSV) via intranasal (i.n.) route.  The enhanced immune responses caused by co-administration of salbutamol provided effective and rapid responses to HSV mucosal challenge, thereby conferring prolonged survival and reduced inflammation against viral infection [PubMed: 19641376]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010834 .

obo:VO_0018510 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0018504 .

obo:VO_0001436 a rdfs:Class ;
  rdfs:label "Hepatitis B virus gene" ;
  rdfs:comment "A viral gene that is from Hepatitis B virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0011049 a rdfs:Class ;
  rdfs:label "FspA2" ;
  rdfs:comment "Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model.  Immunization with FspA2 provided 38.4% (without adjuvant) or 47.2% (with adjuvant) protection against disease from homologous challenge with CG8486 [PubMed: 18426878]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010765 .

obo:VO_0015296 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015292 .

obo:VO_0015946 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015638 , obo:VO_0015720 , obo:VO_0016044 .

obo:VO_0015889 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015620 , obo:VO_0015715 , obo:VO_0016007 .

obo:NCBITaxon_4751 a rdfs:Class ;
  rdfs:label "Fungi" ;
  rdfs:subClassOf obo:NCBITaxon_33154 .

obo:VO_0003623 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003617 .

obo:VO_0017159 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Pediacel] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017158 .

obo:VO_0002205 a rdfs:Class ;
  rdfs:label "Bovine Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 40A5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002489 .

obo:VO_0012181 a rdfs:Class ;
  rdfs:label "Helicobacter pylori vaccine" ;
  rdfs:comment "Vaccine that protects against Helicobacter pylori infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0003881 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML [Flublok 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003878 , obo:VO_0004914 .

obo:VO_0000378 a rdfs:Class ;
  rdfs:label "intravaginal route" ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0015668 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015596 .

obo:VO_0003763 a rdfs:Class ;
  rdfs:label "FluLaval Quadrivalent 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 .

obo:NCBITaxon_3052310 a rdfs:Class ;
  rdfs:label "Mammarenavirus lassaense" ;
  rdfs:subClassOf obo:NCBITaxon_1653394 .

obo:VO_0006084 a rdfs:Class ;
  rdfs:label "typhoid vaccine parenteral other than acetone-killed dried" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010451 .

obo:VO_0001898 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002343 .

obo:VO_0004764 a rdfs:Class ;
  rdfs:label "MG1-hDCT vaccine" ;
  rdfs:comment "Gene name: MAGEA1" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0002911 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium surA mutant vaccine" ;
  rdfs:comment "A surA mutant (BRD1115) is attenuated in BALB/c mice and induces protection from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0007622 a rdfs:Class ;
  rdfs:label "IMM-101 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020194 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA spike protein Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020193 .

obo:VO_0016410 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0000260 a rdfs:Class ;
  rdfs:label "vaccine-induced follicular dendritic cell activation" ;
  rdfs:subClassOf obo:VO_0000180 .

obo:VO_0001147 a rdfs:Class ;
  rdfs:label "IL-12 vacince adjuvant" ;
  rdfs:comment "A cytokine vaccine adjuvant that contains IL-12." ;
  rdfs:subClassOf obo:VO_0001353 .

obo:VO_0002010 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 11A1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002372 .

obo:VO_0016046 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015670 , obo:VO_0015801 .

obo:VO_0011160 a rdfs:Class ;
  rdfs:label "BT1" ;
  rdfs:comment "Immunization of mice with recombinant BT1 proteins (a biopterin transporter) from multigenic LD1 locus on chromosome 35 of L. donovani conferred partial protection against challenge with Leishmania donovani in a BALB/c mice [PubMed: 15357215]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0010067 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii HSP60" ;
  rdfs:comment "A HSP60 protein that is part of Plasmodium yoelii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015474 .

obo:NCBITaxon_104388 a rdfs:Class ;
  rdfs:label "anatid alphaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_180252 .

obo:VO_0000715 a rdfs:Class ;
  rdfs:label "DNA vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0015628 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Fendrix]" ;
  rdfs:subClassOf obo:VO_0015486 , obo:VO_0015587 .

obo:VO_0003425 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0003723 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Afluria 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003721 .

obo:VO_0016449 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0015549 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0001558 a rdfs:Class ;
  rdfs:label "Bovine Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1095.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001507 .

obo:OBI_0302733 a rdfs:Class ;
  rdfs:label "solute role"@en ;
  rdfs:comment "solute role is a role played by a chemical entity which is dissolved by another chemical entity (the solvent) when creating a solution"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:NCBITaxon_11157 a rdfs:Class ;
  rdfs:label "Mononegavirales" ;
  rdfs:subClassOf obo:NCBITaxon_2497569 .

obo:VO_0015598 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003416 .

obo:VO_0003379 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain Injection" ;
  rdfs:subClassOf obo:VO_0003371 .

obo:VO_0015755 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015815 .

obo:VO_0020470 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0000104 , obo:VO_0020472 .

obo:VO_0000512 a rdfs:Class ;
  rdfs:label "Pox vaccine" ;
  rdfs:comment "a viral vaccine against a disease caused by a virus belong to Poxviridae. " ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0007336 a rdfs:Class ;
  rdfs:label "autologous CLL tumor cell vaccine" ;
  rdfs:comment "A cancer vaccine that  consists of of irradiated autologous tumor cells admixed with GM-CSF-secreting bystander cells. The CD8+ T cells can react against CLL-associated antigens. Autologous tumor cell vaccination is an effective strategy to advance long-term leukemia control following allogeneic hematopoietic stem cell transplantation (allo-HSCT). " ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 , obo:VO_0007658 .

obo:DOID_14457 a rdfs:Class ;
  rdfs:label "Brucella abortus brucellosis"@en ;
  rdfs:comment "A brucellosis that involves an infection caused by Brucella abortus [NCBITaxon:235] in cattle and humans. The disease has_symptom fever, has_symptom chills, has_symptom sweats, has_symptom weight loss, has_symptom malaise, has_symptom headaches, has_symptom myalgia, and has_symptom arthralgia."@en ;
  rdfs:subClassOf obo:DOID_11077 .

obo:VO_0003484 a rdfs:Class ;
  rdfs:label "Neisseriales vaccine" ;
  rdfs:comment "Vaccine that protects against Neisseriales infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003532 .

obo:VO_0015144 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015139 , obo:VO_0015310 .

obo:VO_0020598 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Viroflu] by Crucell" ;
  rdfs:subClassOf obo:VO_0020595 .

obo:VO_0004256 a rdfs:Class ;
  rdfs:label "recombinant Tir protein vaccine" ;
  rdfs:subClassOf obo:VO_0000041 , obo:VO_0000484 .

obo:VO_0010798 a rdfs:Class ;
  rdfs:label "Corynebacterium diphtheriae protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:VO_0011222 a rdfs:Class ;
  rdfs:label "VP6 from Murine rotavirus" ;
  rdfs:comment "Intranasal or oral delivery of the chimeric rotavirus VP6 protein MBP::VP6 to mice elicited >90% reductions in fecal rotavirus shedding after murine rotavirus challenge [PubMed: 17629371]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010789 .

obo:OPL_0000313 a rdfs:Class ;
  rdfs:label "Mammalia cerebrospinal fluid" ;
  rdfs:comment "Cerebrospinal fluid that is a part of or originated from a mammal." ;
  rdfs:subClassOf obo:UBERON_0001359 .

obo:VO_0017843 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine Injectable Solution [Bexsero]" ;
  rdfs:subClassOf obo:VO_0003066 , obo:VO_0017894 .

obo:VO_0000324 a rdfs:Class ;
  rdfs:label "pTVG4 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0001974 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1189.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0018616 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus Injection [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0011558 , obo:VO_0018614 .

obo:VO_0002620 a rdfs:Class ;
  rdfs:label "cbiA from Salmonella Gallinarum" ;
  rdfs:comment "A cbiA mutant, in combination with a cobS mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001420 .

obo:VO_0001400 a rdfs:Class ;
  rdfs:label "Brucella melitensis gene" ;
  rdfs:comment "A Brucella gene that is from B. melitensis." ;
  rdfs:subClassOf obo:VO_0000790 .

obo:VO_0017827 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.3 MG/ML [Bexsero]" ;
  rdfs:subClassOf obo:VO_0003066 , obo:VO_0017854 .

obo:VO_0005423 a rdfs:Class ;
  rdfs:label "SLA-SE vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0005162 a rdfs:Class ;
  rdfs:label "ZyCoV-D vaccine" ;
  rdfs:comment "A SARS-CoV-2 plasmid DNA vaccine that encodes the envelope protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005323 .

obo:VO_0002186 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis VG/GA Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 17V1.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0020959 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 UNT/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0000742 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus vaccine" ;
  rdfs:comment "A vaccine that protects against diphtheria, tetanus, pertussis, and poliovirus." ;
  rdfs:subClassOf obo:VO_0000765 , obo:VO_0000943 .

obo:VO_0003393 a rdfs:Class ;
  rdfs:label "TIV Dresden vaccine" ;
  rdfs:comment "A trivalent influenza vaccine contianing two A influenza strains and one B influenza strain." ;
  rdfs:subClassOf obo:VO_0001176 , obo:VO_0003495 .

obo:VO_0011388 a rdfs:Class ;
  rdfs:label "Rickettsia rickettsii vaccine using M. vaccae expressing R. rickettsii OmpA Protein" ;
  rdfs:subClassOf obo:VO_0000767 .

obo:VO_0020798 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 CELLS Injectable Suspension [OncoTICE] by Organon" ;
  rdfs:subClassOf obo:VO_0020797 .

obo:VO_0020442 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 100" ;
  rdfs:subClassOf obo:VO_0020408 , obo:VO_0020418 .

obo:VO_0016289 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0016026 .

obo:VO_0020656 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020702 .

obo:VO_0005458 a rdfs:Class ;
  rdfs:label "influenza, injectable, Madin Darby Canine Kidney, quadrivalent with preservative" ;
  rdfs:subClassOf obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0007467 a rdfs:Class ;
  rdfs:label "GVAX cancer vaccine" ;
  rdfs:comment "GVAX cancer vaccines are autologous cell vaccines comprised of tumor cells which have been irradiated and genetically modified to secrete granulocyte-macrophage colony stimulating factor (GM-CSF), a hormone which plays a key role in stimulating the body's immune response to vaccines." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0005430 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0019468 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide / Neisseria meningitidis Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003192 , obo:VO_0010444 , obo:VO_0020836 .

obo:VO_0015004 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Twinrix]" ;
  rdfs:subClassOf obo:VO_0015005 .

obo:VO_0015725 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [H B Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015574 , obo:VO_0015795 .

obo:VO_0020639 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe [Zostavax] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0020638 .

obo:VO_0002874 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine (merged to VO_0002872)" ;
  rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" .

obo:VO_0006033 a rdfs:Class ;
  rdfs:label "meningococcal C conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0005430 a rdfs:Class ;
  rdfs:label "pancreatic cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is used against pancreatic canceer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0019607 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluad 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020310 .

obo:VO_0011441 a rdfs:Class ;
  rdfs:label "Lassa Virus Nucleoprotein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012177 .

obo:VO_0003387 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003201 .

obo:VO_0016474 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0000193 a rdfs:Class ;
  rdfs:label "Bordetella pertussis component vaccine adjuvant" ;
  rdfs:comment "A microbial derivitive vaccine adjuvant that contains components from killed Bordetella pertussis. The killed B. pertussis has a strong adjuvant effect on the diphtheria and tetanus toxoids in the DPT vaccines." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0003612 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2014-2015 Formula Injectable Product" ;
  rdfs:subClassOf obo:VO_0003611 .

obo:VO_0018081 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 25000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018162 .

obo:VO_0011237 a rdfs:Class ;
  rdfs:label "AMA-1 from P. chabaudi" ;
  rdfs:comment "Mice immunized with a refolded, recombinant, Plasmodium chabaudi AMA1 fragment (AMA1B) can withstand subsequent challenge with P. chabaudi adami [PubMed: 10861076]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015476 .

obo:VO_0018441 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 1" ;
  rdfs:subClassOf obo:VO_0018423 .

obo:VO_0002070 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 12H1.67)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002367 , obo:VO_0007748 .

obo:VO_0011081 a rdfs:Class ;
  rdfs:label "Hpd" ;
  rdfs:comment "Rats vaccinated with PD (hpd) cleared NT H. influenzae better after middle ear and pulmonary bacterial challenge, and chinchillas vaccinated with PD showed significant protection against NT H. influenzae-dependent acute otitis media. In a clinical trial involving children, PD was used as an antigenically active carrier protein in an 11-valent pneumococcal conjugate investigational vaccine; significant protection was achieved against acute otitis media not only caused by pneumococci but also caused by NT H. influenzae [PubMed: 18230042]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:VO_0015101 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Havpur] Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0015100 .

obo:VO_0003945 a rdfs:Class ;
  rdfs:label "Human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML / Human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML [Cervarix]" ;
  rdfs:subClassOf obo:VO_0011559 .

obo:VO_0003232 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 4 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:OPL_0000330 a rdfs:Class ;
  rdfs:label "Plasmodium berghei sporazoite" ;
  rdfs:comment "A Plasmodium berghei is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector." ;
  rdfs:subClassOf obo:NCBITaxon_5821 , obo:OPL_0000278 .

obo:VO_0004007 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae PspA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0011052 a rdfs:Class ;
  rdfs:label "CDVgp6 haemagglutinin protein H" ;
  rdfs:comment "Young mink kits (n=8) were vaccinated with DNA plasmids encoding the viral haemagglutinin protein (H) of a vaccine strain of Canine distemper virus (CDV).  The mink were protected against viraemia, lymphopenia, clinical disease and changes in the percentage of IFN-gamma producing peripheral blood leucocytes after challenge inoculation with a recent wild type strain of CDV. Essentially, these results demonstrate that early life DNA vaccination with the H gene of a CDV vaccine strain induced robust protective immunity against a recent wild type CDV [PubMed: 19596418]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010809 .

obo:VO_0019880 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Flulaval Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020342 .

obo:VO_0017362 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Prefilled Syringe [Dtp Rix]" ;
  rdfs:subClassOf obo:VO_0017361 .

obo:NCBITaxon_444163 a rdfs:Class ;
  rdfs:label "Brucella microti" ;
  rdfs:subClassOf obo:NCBITaxon_234 .

obo:VO_0003268 a rdfs:Class ;
  rdfs:label "Infanrix Quinta vaccine" ;
  rdfs:comment "A combination vaccine against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b (Hib)." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0002668 a rdfs:Class ;
  rdfs:label "aroA from Shigella" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000169 .

obo:NCBITaxon_70796 a rdfs:Class ;
  rdfs:label "Tremovirus A" ;
  rdfs:subClassOf obo:NCBITaxon_2946633 .

obo:VO_0019640 a rdfs:Class ;
  rdfs:label "influenza A virus (H3N2) antigen 0.03 MG/ML / influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0005066 a rdfs:Class ;
  rdfs:label "pCSIVgag DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCSIVgag." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0020002 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML [Fluzone High-Dose 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020484 .

obo:VO_0007416 a rdfs:Class ;
  rdfs:label "monoclonal antibody GD2 anti-idiotype vaccine" ;
  rdfs:comment "An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma, and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005486 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0019615 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flublok Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020324 .

obo:VO_0020827 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020818 .

obo:VO_0016693 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 10 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0001915 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4339.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002349 .

obo:VO_0020318 a rdfs:Class ;
  rdfs:label "Fluarix 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000045 , obo:VO_0000578 , obo:VO_0010417 .

obo:VO_0004989 a rdfs:Class ;
  rdfs:label "obsolete S protein of SARS-CoV-2" .

obo:VO_0017631 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0017682 .

obo:VO_0017572 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 20" ;
  rdfs:subClassOf obo:VO_0017570 , obo:VO_0017578 .

obo:VO_0017478 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0017476 .

obo:VO_0005139 a rdfs:Class ;
  rdfs:label "rSARS-CoV-ΔE vaccine" ;
  rdfs:comment "A SARS recombinant vector vaccine made from a line attenuated and recombinant SARS-CoV lacking the E gene" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0001169 a rdfs:Class ;
  rdfs:label "E. coli DNA vaccine" ;
  rdfs:comment "E. coli DNA vaccine is a DNA vaccine that protects against an E. coli infection." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000041 .

obo:VO_0020909 a rdfs:Class ;
  rdfs:label "Influenza A virus Injectable Suspension [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020907 .

obo:NCBITaxon_5671 a rdfs:Class ;
  rdfs:label "Leishmania infantum" ;
  rdfs:subClassOf obo:NCBITaxon_38574 .

obo:VO_0018763 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension [Stamaril] Box of 1" ;
  rdfs:subClassOf obo:VO_0018762 , obo:VO_0018765 .

obo:VO_0015613 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0015565 , obo:VO_0015659 .

obo:VO_0007254 a rdfs:Class ;
  rdfs:label "Ankara (MVA) vaccine" ;
  rdfs:comment "A modified vaccinia Ankara (MVA) encoding 7 melanoma tumor antigen cytotoxic T lymphocyte (CTL) epitopes." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0004013 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis NspA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0020934 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Intanza]" ;
  rdfs:subClassOf obo:VO_0001248 , obo:VO_0020929 .

obo:VO_0017840 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Prefilled Syringe [Mencevax Acwy]" ;
  rdfs:subClassOf obo:VO_0017892 .

obo:VO_0019707 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML Injection [Flublok 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003890 , obo:VO_0019706 .

obo:VO_0015790 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 20" ;
  rdfs:subClassOf obo:VO_0015491 .

obo:VO_0000432 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae Hap protein vaccine" ;
  rdfs:comment "A subunit nontypeable H. influenzae vaccine that uses Hap protein." ;
  rdfs:subClassOf obo:VO_0000471 .

obo:VO_0017607 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0017973 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017943 , obo:VO_0017960 .

obo:VO_0017242 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Hepatitis B Surface Antigen Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Hibdt]" ;
  rdfs:subClassOf obo:VO_0017241 .

obo:VO_0002685 a rdfs:Class ;
  rdfs:label "aroA from Yersinia enterocolitica" ;
  rdfs:comment "An aroA mutant is highly attenuated in mice, and after 3 doses induces significant protection from challenge with wild type Y. enterocolitica" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001425 .

obo:VO_0001572 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Modified Live Virus Vaccine (USDA: 1201.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0001501 .

obo:DOID_3996 a rdfs:Class ;
  rdfs:label "urinary system cancer"@en ;
  rdfs:comment "An organ system cancer that is located_in the kidneys, ureteres, bladder or urethra."@en ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_18 .

obo:VO_0018352 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG" ;
  rdfs:subClassOf obo:VO_0003339 .

obo:VO_0004477 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine pLAMP1-PA63" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0004925 a rdfs:Class ;
  rdfs:label "senior age" ;
  rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ;
  rdfs:subClassOf obo:VO_0004921 .

obo:VO_0004243 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum MSP4 vaccine with AFCo1 adjuvant vaccine" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0002650 a rdfs:Class ;
  rdfs:label "nmpC from Salmonella Typhimurium" ;
  rdfs:comment "In a pig infection experiment including two oral immunizations with SalmoporcDeltaompD (OmpD, nmpC) and challenge with a multiresistant S. enterica serovar Typhimurium DT104 clinical isolate, we confirmed the protective efficacy of SalmoporcDeltaompD in pigs, showing a significant reduction of both clinical symptoms and colonization of lymph nodes and intestinal tract" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0016503 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Gerke" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:VO_0005490 a rdfs:Class ;
  rdfs:label "gastric cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against gastric cancer" ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0004753 a rdfs:Class ;
  rdfs:label "Ac-CMV-S1 infectious bronchitis virus vaccine" ;
  rdfs:subClassOf obo:VO_0001502 .

obo:VO_0004223 a rdfs:Class ;
  rdfs:label "Bacillus anthracis rPA vaccine with Rehydragel HPA adjuvant" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0002022 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Escherichia Coli Bacterin (USDA: 4585.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0000974 , obo:VO_0002377 .

obo:VO_0004196 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum DNA vaccine encoding EBA-175" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000087 .

obo:DOID_11729 a rdfs:Class ;
  rdfs:label "Lyme disease"@en ;
  rdfs:comment "A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia burgdorferi, which is transmitted_by blacklegged tick (Ixodes scapularis) or transmitted_by western blacklegged tick (Ixodes pacificus). The infection has_symptom fever, has_symptom headache, has_symptom fatigue, and has_symptom skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:NCBITaxon_2497571 a rdfs:Class ;
  rdfs:label "Polyploviricotina" ;
  rdfs:subClassOf obo:NCBITaxon_2497569 .

obo:VO_0011355 a rdfs:Class ;
  rdfs:label "Leishmania amazonensis M3 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012158 .

obo:VO_0020961 a rdfs:Class ;
  rdfs:label "Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0003526 .

obo:VO_0011522 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum DNA vaccine encoding TC0757" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012176 .

obo:VO_0004159 a rdfs:Class ;
  rdfs:label "RASV expressing Yersinia pestis Psn vaccine" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0010056 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum TRAP" ;
  rdfs:comment "A TRAP protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0003433 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010438 .

obo:VO_0015565 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0015534 , obo:VO_0015595 .

obo:BFO_0000019 a rdfs:Class ;
  rdfs:label "quality"@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:VO_0018188 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus Injection [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018186 .

obo:VO_0002609 a rdfs:Class ;
  rdfs:label "rfaF from Neisseria meningitidis" ;
  rdfs:comment "An rfaF mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001417 .

obo:VO_0018267 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated Prefilled Syringe [VACCIN RABIQUE INACTIVE MERIEUX]" ;
  rdfs:subClassOf obo:VO_0018275 .

obo:VO_0019621 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020333 .

obo:VO_0017392 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 LFU/ML / tetanus toxoid vaccine, inactivated 2 LFU/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0017391 .

obo:VO_0003816 a rdfs:Class ;
  rdfs:label "FluMist Quadrivalent, 2017-2018 Formula Nasal Spray" ;
  rdfs:subClassOf obo:VO_0003808 .

obo:VO_0007127 a rdfs:Class ;
  rdfs:label "WT1 Analog Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine comprised of an epitope of human Wilms tumor 1 (WT-1) with potential antineoplastic activity. WT-1, a transcription factor, is overexpressed in most types of leukemia and in some solid cancers. Vaccination with the WT-1 analog peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against WT-1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0005122 a rdfs:Class ;
  rdfs:label "MERS-CoV pcDNA3.1-S1 DNA vaccine" ;
  rdfs:comment "A MERS DNA vaccine made of plasmid that encodes the first 725 amino acids of S from MERS-CoV" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0004900 .

obo:PATO_0000011 a rdfs:Class ;
  rdfs:label "age" ;
  rdfs:comment "A time quality inhering in a bearer by virtue of how long the bearer has existed." ;
  rdfs:subClassOf obo:PATO_0000165 .

obo:VO_0015692 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 20" ;
  rdfs:subClassOf obo:VO_0015566 , obo:VO_0015779 .

obo:VO_0015653 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015559 , obo:VO_0015599 .

obo:VO_0016174 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1 by GSK" ;
  rdfs:subClassOf obo:VO_0015892 , obo:VO_0015894 .

obo:VO_0000302 a rdfs:Class ;
  rdfs:label "pRc/CMV2 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016397 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1 by Waymade" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0010475 a rdfs:Class ;
  rdfs:label "licensed mink vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000363 , obo:VO_0001464 .

obo:VO_0010197 a rdfs:Class ;
  rdfs:label "influenza, seasonal, Southern Hemisphere, high-dose, quadrivalent, 0.7mL dose, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0007135 a rdfs:Class ;
  rdfs:label "PA-1-STK Ovarian Carcinoma Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine with potential antineoplastic activity. PA-1-STK ovarian carcinoma vaccine is produced by transducing the ovarian cancer cell line, PA-1, with the herpes simplex thymidine kinase (HSV-tk) gene, resulting in a cell line, PA-1-STK, that permanently expresses the HSV tk gene. Upon transfection into malignant cells, this vaccine is capable of sensitizing tumor cells in response to an antiviral drug such as ganciclovir, which is readily phosphorylated by the TK enzyme to its active form. Administration of ganciclovir following PA-1 STK transfection results in enhanced cytotoxicity of the transfected tumor cells. Additionally, adjacent non-transfected cells are also killed by the activated antiviral drug, a phenomenon referred to as the bystander effect that occurs with this type of suicide-gene transfer technique." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0010205 a rdfs:Class ;
  rdfs:label "meningococcal B vaccine, fully recombinant" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0010444 .

obo:VO_0003495 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0004941 a rdfs:Class ;
  rdfs:label "human age 7 to 10 years at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0000969 a rdfs:Class ;
  rdfs:label "nkCMVint DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label nkCMVint." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016514 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0002728 a rdfs:Class ;
  rdfs:label "M2-2 from Human Respiratory Syncytial Virus" ;
  rdfs:comment "An M2-2 mutant of human respiratory syncytial virus A2 is attenuated in African green monkeys. When challenged with wild type RSV, two doses provided complete protection against challenge in the lower respiratory tract and a significant reduction of the challenge virus in the upper respiratory tract" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001439 .

obo:VO_0004423 a rdfs:Class ;
  rdfs:label "VEE virus recombinant vector vaccine RAd/VEEV#2" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0001499 .

obo:VO_0021099 a rdfs:Class ;
  rdfs:label "influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Fluad Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020312 .

obo:VO_0020561 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Stada]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020863 .

obo:VO_0000492 a rdfs:Class ;
  rdfs:label "passive immunization" ;
  rdfs:comment "An immunization where pre-synthesized elements of the immune system are transferred to an organism so that the body does not need to produce these elements itself." ;
  rdfs:subClassOf obo:OBI_0000011 , obo:VO_0000490 .

obo:VO_0016057 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0003420 .

obo:VO_0020082 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain 158000000 UNT/ML [FluMist 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020347 .

obo:VO_0017838 a rdfs:Class ;
  rdfs:label "influenza B virus antigen, Hong Kong 330-2001 / meningococcal group C polysaccharide Injection [Menitorix]" ;
  rdfs:subClassOf obo:VO_0017890 .

obo:VO_0007443 a rdfs:Class ;
  rdfs:label "human papillomavirus  16 E6 (18-26) peptide vaccine" ;
  rdfs:comment "A peptide derived from the oncogenic human papillomavirus (HPV) early gene product E6. The HPV 16 transforming protein E6 is expressed in precancerous and malignant cervical lesions and has a high affinity for the most common human lymphocyte antigen (HLA), HLA-A2. Immunogenic peptides from the HPV 16 E6 may be used to trigger a T-cell-mediated immune response to HPV." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0004872 a rdfs:Class ;
  rdfs:label "Adenovirus Type 4 Vaccine Live Oral Product" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003175 .

obo:VO_0001136 a rdfs:Class ;
  rdfs:label "live attenuated Brucella suis vaccine" ;
  rdfs:comment "live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella suis infection." ;
  rdfs:subClassOf obo:VO_0000721 , obo:VO_0001127 .

obo:VO_0001479 a rdfs:Class ;
  rdfs:label "vaccine target specification" ;
  rdfs:comment "The objective that intends to produce vaccine via the vaccine preparation process." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:VO_0002657 a rdfs:Class ;
  rdfs:label "rpoB from Salmonella Typhimurium" ;
  rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0019595 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Nasal Spray [Flumist Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003808 , obo:VO_0019592 .

obo:VO_0002155 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.19)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0015736 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015801 .

obo:VO_0016835 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.2 LFU/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0016757 .

obo:VO_0003368 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0010444 .

obo:VO_0004714 a rdfs:Class ;
  rdfs:label "rMV-Ed-G vaccine" ;
  rdfs:subClassOf obo:VO_0012169 .

obo:OBI_0000434 a rdfs:Class ;
  rdfs:label "adding material objective"@en ;
  rdfs:comment "is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity"@en ;
  rdfs:subClassOf obo:OBI_0000686 .

obo:VO_0020303 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2019-2020 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0001817 , obo:VO_0010420 .

obo:VO_0020804 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0019465 .

obo:VO_0017430 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0017672 , obo:VO_0020836 .

obo:VO_0004087 a rdfs:Class ;
  rdfs:label "VSV[Delta]G/LVGPC vaccine" ;
  rdfs:subClassOf obo:VO_0012177 .

obo:VO_0005250 a rdfs:Class ;
  rdfs:label "KD-414 vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by KM Biologics Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005201 .

obo:VO_0016689 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0001954 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B6.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002360 .

obo:VO_0019669 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML [Fluzone 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020483 .

obo:VO_0015576 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015493 , obo:VO_0015539 , obo:VO_0015540 .

obo:VO_0016438 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Mevita" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0002011 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 11A1.26)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002372 .

obo:VO_0002817 a rdfs:Class ;
  rdfs:label "obsolete B. melitensis omp31 mutant vaccine" ;
  rdfs:comment "A omp31 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice" .

obo:VO_0002278 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002461 , obo:VO_0007748 .

obo:VO_0018225 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 5000 UNT / Rubella virus 1000 UNT Injection" ;
  rdfs:subClassOf obo:VO_0018250 .

obo:VO_0016105 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 20 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015994 .

obo:VO_0019868 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Flulaval Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020342 .

obo:VO_0004406 a rdfs:Class ;
  rdfs:label "Insulin-dependent diabetes mellitus DNA vaccine JwGAD65 + IL-4" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002811 .

obo:VO_0019257 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010433 .

obo:VO_0019100 a rdfs:Class ;
  rdfs:label "nasal spray" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:DOID_0050615 a rdfs:Class ;
  rdfs:label "respiratory system cancer"@en ;
  rdfs:comment "An organ system cancer located_in the respiratory system that is characterized by uncontrolled cellular proliferation in the respiratory tract."@en ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_1579 .

obo:NCBITaxon_5864 a rdfs:Class ;
  rdfs:label "Babesia" ;
  rdfs:subClassOf obo:NCBITaxon_5863 .

obo:VO_0003660 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010309 , obo:VO_0010415 .

obo:VO_0004407 a rdfs:Class ;
  rdfs:label "Adjuvant arthritis DNA vaccine pCMV3.65 encoding HSP65" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002823 .

obo:VO_0018329 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0018318 .

obo:VO_0002700 a rdfs:Class ;
  rdfs:label "US8 from Bovine herpesvirus 1" ;
  rdfs:comment "A deletion of BHV-1 gE gene in strain A is considered as a live attenuated vaccine. After challenge, vaccinated calves were protected against disease and virus shedding was reduced" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001424 .

obo:VO_0015693 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 50" ;
  rdfs:subClassOf obo:VO_0015566 , obo:VO_0015782 .

obo:VO_0001858 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0002436 , obo:VO_0007748 .

obo:VO_0017166 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] Box of 2" ;
  rdfs:subClassOf obo:VO_0017163 , obo:VO_0017184 , obo:VO_0017618 .

obo:VO_0015606 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015557 , obo:VO_0015589 , obo:VO_0015653 .

obo:VO_0017283 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017230 .

obo:VO_0002863 a rdfs:Class ;
  rdfs:label "Salmonella typhi aroA mutant vaccine" ;
  rdfs:comment "An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. typhi Ty2" ;
  rdfs:subClassOf obo:VO_0000671 .

obo:VO_0018627 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 1 UNT [Je-Vax]" ;
  rdfs:subClassOf obo:VO_0000066 , obo:VO_0018626 .

obo:VO_0019528 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.02 MG/ML Injectable Suspension [HB-VAX]" ;
  rdfs:subClassOf obo:VO_0015493 , obo:VO_0019534 .

obo:VO_0005077 a rdfs:Class ;
  rdfs:label "pcDNA3.1(Zeo)+ DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1(Zeo)+.  This plasmid is 5015 base pairs in length and contains a zeocin selectable marker, a CMV promoter, and an ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015646 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0015581 , obo:VO_0015671 .

obo:VO_0001074 a rdfs:Class ;
  rdfs:label "Babesia canis vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0020764 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG Injectable Solution [OncoTICE] by Merck" ;
  rdfs:subClassOf obo:VO_0020761 .

obo:VO_0004525 a rdfs:Class ;
  rdfs:label "Avian pneumovirus DNA vaccine expressing the F gene" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001514 .

obo:VO_0020931 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Fluarix]" ;
  rdfs:subClassOf obo:VO_0000045 , obo:VO_0020929 .

obo:VO_0006105 a rdfs:Class ;
  rdfs:label "precision vaccines program-057 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant which is a small molecule adjuvant that is able to induce a mixed Th1/Th2 response and active innate immunity. " ;
  rdfs:subClassOf obo:VO_0000580 .

obo:OPL_0000241 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum hepatic merozoite" ;
  rdfs:comment "A Plasmodium falciparum merozoite that is produced in a hepatic schizont and released into the bloodstream of a human host. These forms invade erythrocytes." ;
  rdfs:subClassOf obo:OPL_0000130 , obo:OPL_0000272 .

obo:VO_0016630 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 1" ;
  rdfs:subClassOf obo:VO_0016563 , obo:VO_0016614 .

obo:VO_0019299 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020481 .

obo:VO_0001486 a rdfs:Class ;
  rdfs:label "Equid herpesvirus 1 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Equid herpesvirus 1 infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003537 .

obo:NCBITaxon_162145 a rdfs:Class ;
  rdfs:label "human metapneumovirus" ;
  rdfs:subClassOf obo:NCBITaxon_162387 .

obo:DOID_4362 a rdfs:Class ;
  rdfs:label "cervical cancer"@en ;
  rdfs:comment "A female reproductive organ cancer that is located_in the cervix."@en ;
  rdfs:subClassOf obo:DOID_363 .

obo:VO_0001805 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus Modified Live Virus Vaccine (USDA: 19E1.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001495 , obo:VO_0007748 .

obo:VO_0006007 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b vaccine PRP-D conjugate" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010437 .

obo:VO_0011006 a rdfs:Class ;
  rdfs:label "Irp7" ;
  rdfs:comment "Using a mouse plague model, YPO1914 (irp7) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0002765 a rdfs:Class ;
  rdfs:label "UP from Toxoplasma gondii" ;
  rdfs:comment "A UP mutant, in combination with an OMPDC mutation, is attenuated in mice and induces significant protection from wild type T. gondii" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001453 .

obo:VO_0020348 a rdfs:Class ;
  rdfs:label "Flumist 2011-2012 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000044 , obo:VO_0010419 .

obo:VO_0001659 a rdfs:Class ;
  rdfs:label "Bursal Disease Variant, Live Virus Vaccine (USDA: 12L1.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0007558 a rdfs:Class ;
  rdfs:label "MOv-PBL Vaccine" ;
  rdfs:comment "Peripheral blood lymphocytes (PBL) transfected to express MOv have been designed for possible use in autologous adoptive cellular immunotherapy of ovarian adenocarcinomas that overexpress folate-binding protein. MOv-PBLs express MOv-gamma (MOv), a chimeric receptor gene product derived from a recombinant gene encoding the variable region of murine monoclonal antibody MOv18 against folate-binding protein (FBP), often overexpressed in human ovarian cancer cells, and the human gene encoding the IgG and IgE Fc receptor gamma subunit. Autologous vaccination with these PBLs stimulates a host cytotoxic T lymphocyte response against ovarian cancer cells that overexpress FBP." ;
  rdfs:subClassOf obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0019503 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Prefilled Syringe [Havrix]" ;
  rdfs:subClassOf obo:VO_0003827 , obo:VO_0015279 , obo:VO_0019502 .

obo:VO_0015112 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015111 .

obo:VO_0003167 a rdfs:Class ;
  rdfs:label "Oral Poliovirus vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010447 .

obo:VO_0010103 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii MIC1" ;
  rdfs:comment "A MIC1 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0015949 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites] Box of 3" ;
  rdfs:subClassOf obo:VO_0015639 , obo:VO_0015723 , obo:VO_0016044 .

obo:VO_0004447 a rdfs:Class ;
  rdfs:label "Prostate cancer DNA vaccine rPSMAt encoding PSMA" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0015168 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Gerke" ;
  rdfs:subClassOf obo:VO_0015164 .

obo:VO_0016778 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0016721 .

obo:VO_0001339 a rdfs:Class ;
  rdfs:label "cationic liposome-DNA complex JVRS-100 vaccin adjuvant" ;
  rdfs:comment "A liposome-based vaccine adjuvant that is composed of virus sized liposomes that contain a DNA plasmid." ;
  rdfs:subClassOf obo:VO_0000366 .

obo:VO_0016049 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 250" ;
  rdfs:subClassOf obo:VO_0015670 , obo:VO_0015804 .

obo:VO_0017467 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 1.5 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017465 , obo:VO_0017466 .

obo:VO_0018853 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010301 , obo:VO_0010415 .

obo:VO_0004906 a rdfs:Class ;
  rdfs:label "MERS-CoV protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:OPL_0000290 a rdfs:Class ;
  rdfs:label "Plasmodium macrogametocyte stage" ;
  rdfs:comment "A macrogametocyte stage in the Plasmodium lifecycle that occurs either in the bloodstream of a vertebrate host or the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000028 , obo:OPL_0000289 .

obo:VO_0017087 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Covaxis] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017084 .

obo:VO_0015268 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0015262 , obo:VO_0015267 .

obo:VO_0016204 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 50 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015903 .

obo:VO_0001380 a rdfs:Class ;
  rdfs:label "B16 Vaccine adjuvanted by Loxoribine" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0019207 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0019710 .

obo:VO_0001073 a rdfs:Class ;
  rdfs:label "CMV vaccine vector" ;
  rdfs:comment "a herpesvirus vaccine vector that uses a CMV virus strain" ;
  rdfs:subClassOf obo:VO_0000283 .

obo:VO_0016838 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0016759 .

obo:VO_0005115 a rdfs:Class ;
  rdfs:label "SARS Ad S/N vaccine" ;
  rdfs:comment "A SARS recombinant vector vaccine made of combination of two adenovirus-based vectors, one expressing the nucleocapsid (N) and the other expressing the spike (S) protein" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0003001 a rdfs:Class ;
  rdfs:label "obsolete WEEV Subunit E2 Protein Vaccine" ;
  rdfs:comment "A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" .

obo:VO_0019897 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Fluzone 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019889 , obo:VO_0020482 .

obo:VO_0010164 a rdfs:Class ;
  rdfs:label "non-US diphtheria, tetanus toxoids and acellular pertussis vaccine, Haemophilus influenzae type b conjugate, and poliovirus vaccine, inactivated (DTaP-Hib-IPV)" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0019945 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Flucelvax 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020329 .

obo:VO_0019592 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:OPL_0000171 a rdfs:Class ;
  rdfs:label "human parasite role" ;
  rdfs:comment "A parasite role which is realized only during parasitic infection of a human." ;
  rdfs:subClassOf obo:IDO_0000403 .

obo:NCBITaxon_7164 a rdfs:Class ;
  rdfs:label "Anopheles <genus>" ;
  rdfs:subClassOf obo:NCBITaxon_33340 .

obo:VO_0002762 a rdfs:Class ;
  rdfs:label "mic2 from Toxoplasma gondii" ;
  rdfs:comment "A mic2 mutant is attenuated in mice and induces protection from challenge with wild type T. gondii" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001453 .

obo:VO_0006004 a rdfs:Class ;
  rdfs:label "cholera live attenuated" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000763 , obo:VO_0001217 , obo:VO_0010455 .

obo:VO_0001254 a rdfs:Class ;
  rdfs:label "capsular polysaccharide of pathogen organism as vaccine component" ;
  rdfs:subClassOf obo:VO_0001256 .

obo:VO_0001080 a rdfs:Class ;
  rdfs:label "Androstenedione" ;
  rdfs:subClassOf obo:FMA_12278 .

obo:VO_0018054 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 10" ;
  rdfs:subClassOf obo:VO_0018053 , obo:VO_0018075 , obo:VO_0018145 .

obo:VO_0005101 a rdfs:Class ;
  rdfs:label "SARS N + SARS M DNA vaccine" ;
  rdfs:comment "A SARS DNA combination vaccine that is made from recombinant plasmids' containing membrane protein (M) and nucleocapsid protein (N) sequences constructed then expressed and purified from E. coli bacteria." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012183 .

obo:OPL_0000137 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum sporozoite" ;
  rdfs:comment "A Plasmodium falciparum is formed in the oocyst. It migrates to and resides in the salivary glands of the mosquito vector. A distinction is made between oocyst-derived and salivary gland-derived sporozoites. Sporozoites invade hepatocytes in the vertebrate host." ;
  rdfs:subClassOf obo:NCBITaxon_5833 , obo:OPL_0000278 .

obo:VO_0003997 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 .

obo:VO_0020388 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0020384 .

obo:VO_0001925 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002353 .

obo:VO_0016228 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015906 .

obo:VO_0016723 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0016708 , obo:VO_0016733 .

obo:VO_0002060 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Standard & Variant, Mass & Ark Types, Killed Virus Vaccine (USDA: 12D5.45)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002367 , obo:VO_0007748 .

obo:VO_0002080 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass & Ark Types, Killed Virus Vaccine (USDA: 12M5.42)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0016678 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML [Infanrix]" ;
  rdfs:subClassOf obo:VO_0016705 .

obo:VO_0016690 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Tetravac]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0010212 a rdfs:Class ;
  rdfs:label "rabies vaccine, for intramuscular injection RETIRED CODE" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010448 .

obo:VO_0019688 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003627 .

obo:VO_0015281 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015283 , obo:VO_0019503 .

obo:VO_0015173 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Veron" ;
  rdfs:subClassOf obo:VO_0015164 .

obo:VO_0010367 a rdfs:Class ;
  rdfs:label "(Squeezable Tube Presentation) - ROTARIX vaccine" ;
  rdfs:subClassOf obo:VO_0010738 .

obo:VO_0017258 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 , obo:VO_0017801 , obo:VO_0018770 .

obo:VO_0004501 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine p-Beta-actinH7HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0020027 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injectable Suspension [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020019 , obo:VO_0020479 .

obo:VO_0003292 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003339 .

obo:VO_0002058 a rdfs:Class ;
  rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.04)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002385 , obo:VO_0007748 .

obo:VO_0002594 a rdfs:Class ;
  rdfs:label "galU from Francisella tularensis" ;
  rdfs:comment "A galU mutant is attenuated in mice, with only transient weight loss observed. Two months after inoculation, mice were challenge with wild type F. tularensis and were protected, once again only experiencing transient weight loss" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0000641 a rdfs:Class ;
  rdfs:label "combination vaccine" ;
  rdfs:comment """Combination vaccine is a vaccine that induces protection against multiple infectious diseases or several different serotypes of the same organism. The anitgens contained in combination vaccines are either formulated together by the manufacturer or physically mixed by a health care provider just prior to administration. Both approaches require licensure.
Ref: Baylor NW and Midthum K. Regulation and testing of vaccines. In: Vaccines (Editors: Plotkin S, Orenstein W, and Offit P). 2008.  p1624.""" ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0003768 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003767 .

obo:VO_0010287 a rdfs:Class ;
  rdfs:label "viral neutralization titer assay" ;
  rdfs:comment "An assay that measures the titer of antibodies that neturalize a pathogen within an organism." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:VO_0003921 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Fluad 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003911 .

obo:VO_0007369 a rdfs:Class ;
  rdfs:label "Dendritic Cell-Autologous Lung Tumor Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of lymphocytes harvested from a patient with lung cancer and induced to become antigen-presenting cells (APCs) known as dendritic cells. The dendritic cells are transduced with the gene encoding an antigen specific to the patient's cancer and then returned to the patient. In the host, the altered cells stimulate the immune system to mount a primary T cell response against lung tumor cells expressing the target antigen. Dendritic cell-autologous lung tumor vaccines have been investigated for use in cancer immunotherapy." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0011486 a rdfs:Class ;
  rdfs:label "SARS subunit spike protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012183 .

obo:VO_0018713 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injection" ;
  rdfs:subClassOf obo:VO_0015054 .

obo:VO_0017112 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur] Box of 2 by Novartis" ;
  rdfs:subClassOf obo:VO_0017111 .

obo:VO_0019857 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML [Flublok Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020326 .

obo:VO_0020753 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017681 .

obo:VO_0005274 a rdfs:Class ;
  rdfs:label "Th1 immunity stimulatory role" ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0004372 a rdfs:Class ;
  rdfs:label "Rabies virus DNA vaccine encoding the ERA glycoprotein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000650 .

obo:VO_0018084 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018166 .

obo:VO_0020890 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Fluad]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0019420 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.069 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.0016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.0032 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.0064 MG/ML / diphtheria toxoid vaccine, inactivated 18 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [ACEL-IMUNE]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0003442 , obo:VO_0010435 .

obo:VO_0002166 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.1A)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0011446 a rdfs:Class ;
  rdfs:label "Francisella tularensis GroEL protein vaccine" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0001264 a rdfs:Class ;
  rdfs:label "AS02 vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant comprised of monophosphoryl lipid A (MPL), QS21 and an oil in water emulsion." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0016795 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0016722 , obo:VO_0016737 , obo:VO_0016821 .

obo:VO_0020093 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0003521 .

obo:VO_0020199 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0020497 .

obo:VO_0020419 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 50" ;
  rdfs:subClassOf obo:VO_0020391 , obo:VO_0020429 .

obo:VO_0004637 a rdfs:Class ;
  rdfs:label "HS93Tox-/pIG-T1K vaccine" ;
  rdfs:subClassOf obo:VO_0001130 , obo:VO_0001474 .

obo:VO_0001503 a rdfs:Class ;
  rdfs:label "bovine coronavirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Bovine coronavirus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0004897 .

obo:VO_0001468 a rdfs:Class ;
  rdfs:label "chicken vaccine" ;
  rdfs:comment "Vaccine that used for immunizing chicken." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001461 .

obo:VO_0017486 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [T Immun] Box of 10" ;
  rdfs:subClassOf obo:VO_0017484 , obo:VO_0017497 .

obo:VO_0019488 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.265 MG/ML Injection [PedvaxHIB]" ;
  rdfs:subClassOf obo:VO_0000083 , obo:VO_0010444 , obo:VO_0019487 .

obo:VO_0007400 a rdfs:Class ;
  rdfs:label "Bcr-Abl peptide vaccine" ;
  rdfs:comment "A cancer vaccine consisting of the bcr-abl b3a2 fusion oncoprotein, frequently expressed in chronic myelogenous leukemia (CML), with potential antineoplastic activity. Vaccination with the bcr-abl (b3a2)-derived peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express the bcr-abl b3a2 fusion protein. The bcr-abl p210-b3a2 breakpoint-derived pentapeptide vaccine is used in combination with GM-CSF. The peptides may help the body build an effective immune response to kill cancer cells, and the GM-CSF may increase the number of immune cells found in bone marrow or peripheral blood. This combination is used to treat patients with Philadelphia chromosome-positive chronic myelogenous leukemia. It can also be used in combination with imatinib mesylate to decrease or eliminate all evidence of disease in patients who have CML that is in remission after treatment with imatinib mesylate, but who still have small amounts of detectable disease" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0020538 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020851 .

obo:VO_0007315 a rdfs:Class ;
  rdfs:label "Autologous Sarcoma Lysate-pulsed Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from sarcoma cells with potential immunostimulatory and antineoplastic activities. Upon administration, the autologous sarcoma lysate-pulsed dendritic cell vaccine exposes the immune system to an undefined amount of sarcoma-type tumor associated antigens (TAA), which may result in the induction of both specific anti-tumoral cytotoxic T lymphocytes (CTL) and antibody-dependent responses against the sarcoma TAA-expressing cells, resulting in sarcoma cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0001588 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.12)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001220 , obo:VO_0001522 , obo:VO_0007748 .

obo:VO_0018655 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection [Cervarix] Box of 10" ;
  rdfs:subClassOf obo:VO_0018654 , obo:VO_0018657 .

obo:VO_0016625 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015003 .

obo:VO_0020712 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1920000000 CFU Injection" ;
  rdfs:subClassOf obo:VO_0020710 , obo:VO_0020740 .

obo:VO_0000183 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus gene" ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0015809 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 25" ;
  rdfs:subClassOf obo:VO_0015494 .

obo:VO_0016604 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0016589 , obo:VO_0016596 .

obo:VO_0002002 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.26)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:VO_0019770 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML [Fluad Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020311 .

obo:VO_0004111 a rdfs:Class ;
  rdfs:label "Chimeric SIN/VEE Virus SIN-83 vaccine" ;
  rdfs:subClassOf obo:VO_0001499 .

obo:VO_0000873 a rdfs:Class ;
  rdfs:label "PGA/ME vaccine" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0002828 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei purN mutant vaccine" ;
  rdfs:comment "Although 30:93a purN -immunized mice were challenged with a 10-fold higher dose of WT E8, mice were strongly protected and showed no signs of clinical illness until the experiment was terminated" ;
  rdfs:subClassOf obo:VO_0012175 .

obo:VO_0011537 a rdfs:Class ;
  rdfs:label "Measles Virus vaccine VVM" ;
  rdfs:subClassOf obo:VO_0000654 .

obo:VO_0015912 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [VACCIN GENHEVAC B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015627 , obo:VO_0015765 , obo:VO_0016021 .

obo:VO_0004120 a rdfs:Class ;
  rdfs:label "Chimaeric HBV core particles carrying Puumala virus nucleocapsid protein fragments vaccine" ;
  rdfs:subClassOf obo:VO_0012167 .

obo:VO_0018214 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus 1000 UNT / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2000 PFU Injection" ;
  rdfs:subClassOf obo:VO_0018247 .

obo:VO_0002504 a rdfs:Class ;
  rdfs:label "Streptococcus equi gene" ;
  rdfs:comment "A bacterial gene that is from Streptococcus equi." ;
  rdfs:subClassOf obo:VO_0002503 .

obo:VO_0015901 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015624 , obo:VO_0016016 .

obo:VO_0000705 a rdfs:Class ;
  rdfs:label "vaccine specific antibody test" ;
  rdfs:subClassOf obo:VO_0000584 .

obo:VO_0019514 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen (isoform L), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform M), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform S), recombinant 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0015841 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] by Organon" ;
  rdfs:subClassOf obo:VO_0015633 .

obo:VO_0001321 a rdfs:Class ;
  rdfs:label "LTR192G vaccine adjuvant" ;
  rdfs:comment "An E. coli LT toxin derived vaccine adjuvant that is a mutant form of E.coli heat-labile toxin." ;
  rdfs:subClassOf obo:VO_0000388 .

obo:NCBITaxon_1314 a rdfs:Class ;
  rdfs:label "Streptococcus pyogenes" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:VO_0001185 a rdfs:Class ;
  rdfs:label "Inovocox vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:VO_0001352 a rdfs:Class ;
  rdfs:label "ty particles vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant made of virus like particles (VLPS) containing the yeast retrotransposon Ty which has the amino acids 1-381 of the pI protein encoded." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0000771 a rdfs:Class ;
  rdfs:label "BCG vaccine" ;
  rdfs:comment "BCG Vaccine is a Mycobacterium tuberculosis vaccine that is a live attenuated strain of Mycobacterium bovis (Bacillus Calmette Guerin; BCG)." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0010443 .

obo:VO_0004721 a rdfs:Class ;
  rdfs:label "CVD 103-HgR- REPEC vaccine" ;
  rdfs:subClassOf obo:VO_0000041 .

obo:VO_0003693 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0000983 .

obo:VO_0002439 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Rabies Vaccine" ;
  rdfs:subClassOf obo:VO_0000650 , obo:VO_0002436 .

obo:VO_0019956 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Fluvirin 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019952 , obo:VO_0020476 .

obo:VO_0000154 a rdfs:Class ;
  rdfs:label "sodC from B. abortus strain 2308" ;
  rdfs:comment "A Brucella abortus gene that has the name sodC and comes from strain 2308. " ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000793 , obo:VO_0001232 .

obo:VO_0018452 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumopur] Box of 10" ;
  rdfs:subClassOf obo:VO_0018431 , obo:VO_0018436 .

obo:VO_0020785 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 ORGANISMS Injectable Suspension [OncoTICE] Box of 1 by MSD" ;
  rdfs:subClassOf obo:VO_0020784 .

obo:OPL_0000252 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum oocyst-derived sporozoite stage" ;
  rdfs:comment "A sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the human host." ;
  rdfs:subClassOf obo:OPL_0000115 , obo:OPL_0000256 , obo:OPL_0000301 .

obo:VO_0020171 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) Prefilled Syringe [Ipol]" ;
  rdfs:subClassOf obo:VO_0000054 , obo:VO_0020170 .

obo:VO_0018720 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018717 .

obo:VO_0002175 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1791.19)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0010847 a rdfs:Class ;
  rdfs:label "Bordetella pertussis protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0004341 a rdfs:Class ;
  rdfs:label "Human cytomegalovirus DNA vaccine VCL-CB01 encoding phosphoprotein 65 and gB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000455 , obo:VO_0001227 .

obo:VO_0019517 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.0025 MG/ML [Recombivax]" ;
  rdfs:subClassOf obo:VO_0019516 .

obo:VO_0019348 a rdfs:Class ;
  rdfs:label "0.5 ML Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.008 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0010210 , obo:VO_0010445 .

obo:VO_0003039 a rdfs:Class ;
  rdfs:label "Alkest TW 20 vaccine stabilizer" ;
  rdfs:comment "a polysorbate 20 vaccine stabilizer that is Alkest TW20." ;
  rdfs:subClassOf obo:VO_0000929 .

obo:VO_0004668 a rdfs:Class ;
  rdfs:label "Schistosoma gordonii -M6-Sj-F1 vaccine" ;
  rdfs:subClassOf obo:VO_0001229 .

obo:VO_0015935 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015636 , obo:VO_0016036 .

obo:VO_0018771 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0001648 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.40)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0010146 a rdfs:Class ;
  rdfs:label "Meningococcal polysaccharide (groups A, C, Y, W) tetanus toxoid conjugate, meningococcal B recombinant vaccine, 0.5mL, preservative free" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0019450 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:NCBITaxon_11292 a rdfs:Class ;
  rdfs:label "Lyssavirus rabies" ;
  rdfs:subClassOf obo:NCBITaxon_11286 .

obo:VO_0004109 a rdfs:Class ;
  rdfs:label "recombinant RNA replicons from attenuated VEE virus vaccine" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0001499 .

obo:VO_0003087 a rdfs:Class ;
  rdfs:label "obsolete RB51 induced immune response without protection" .

obo:VO_0019371 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0020175 .

obo:VO_0002279 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.21)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002461 , obo:VO_0007748 .

obo:VO_0001761 a rdfs:Class ;
  rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0000712 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0005038 a rdfs:Class ;
  rdfs:label "pUMVC4b DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pUMVC4b.  This plasmid is 4478 base pairs in length and contains a CMV promoter and kanamycin and ampicillin resistance genes." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000194 a rdfs:Class ;
  rdfs:label "FDA licensed vaccine role" ;
  rdfs:comment "a USA licensed vaccine role that inheres ina vaccine approven to be by the US FDA to be used for humans in the USA. " ;
  rdfs:subClassOf obo:VO_0000812 .

obo:VO_0007440 a rdfs:Class ;
  rdfs:label "HCV DNA Vaccine INO-8000" ;
  rdfs:comment "A multi-antigen DNA vaccine consisting of plasmids encoding the hepatitis C virus (HCV) nonstructural proteins 3 (NS3), 4A (NS4A), 4B (NS4B) and 5A (NS5A), with potential immunomodulating and cancer preventive activities. Administered via intramuscular injection followed by electroporation, cells transfected with the HCV DNA vaccine INO-8000 express the encoded HCV proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against HCV-infected liver cells expressing the NS3, NS4A, NS4B or NS5A proteins. This results in the eradication of HCV-infected cells. HCV, a small, enveloped, single-stranded RNA virus belonging to the Flaviviridae family, is associated with the development of hepatocellular carcinoma (HCC)" ;
  rdfs:subClassOf obo:VO_0005499 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0016366 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0004683 a rdfs:Class ;
  rdfs:label "rNDV-H6 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0019193 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020324 .

obo:VO_0002356 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002488 .

obo:VO_0001739 a rdfs:Class ;
  rdfs:label "Riemerella Anatipestifer Avirulent Live Culture Vaccine (USDA: 1811.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000563 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0001512 , obo:VO_0007748 , obo:VO_0007749 .

obo:VO_0019915 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Injectable Solution [Flublok 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0003874 , obo:VO_0019914 .

obo:VO_0018143 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018135 , obo:VO_0018179 .

obo:VO_0016095 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015992 .

obo:VO_0004838 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0017895 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003347 .

obo:VO_0001965 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4466.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002364 .

obo:VO_0001328 a rdfs:Class ;
  rdfs:label "imiquimod vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant contiaing imiquimod a imidazoquinoline." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0018412 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 5 vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003255 .

obo:VO_0016975 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0017438 .

obo:VO_0001253 a rdfs:Class ;
  rdfs:label "capsular polysaccharide subunit vaccine" ;
  rdfs:subClassOf obo:VO_0001255 .

obo:VO_0005469 a rdfs:Class ;
  rdfs:label "trivalent poliovirus vaccine, live, oral" ;
  rdfs:comment "A poliovirus vaccine that contains three types of poliovirus and uses poliovirus particles that have been grown under controlled conditions and then killed to prevent disease caused from the vaccine." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010447 .

obo:VO_0017267 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection Box of 5" ;
  rdfs:subClassOf obo:VO_0017264 .

obo:VO_0005195 a rdfs:Class ;
  rdfs:label "V590 vaccine" ;
  rdfs:comment "A SARS-CoV-2 vaccine that uses a recombinant vesicular stomatitis virus (rVSV) platform, and is made by Merck. Development of the vaccine was discontinued on January 25, 2021." ;
  rdfs:subClassOf obo:VO_0005199 .

obo:VO_0017163 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017616 .

obo:VO_0000143 a rdfs:Class ;
  rdfs:label "cholera toxin vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant consisting of cholera toxin (CT) from Vibrio cholerae." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0017231 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Adacel]" ;
  rdfs:subClassOf obo:VO_0000005 , obo:VO_0017230 .

obo:VO_0017272 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.008 MG / Bordetella pertussis 0.05 MG / diphtheria toxoid vaccine, inactivated 30 UNT / tetanus toxoid vaccine, inactivated 40 UNT Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017225 .

obo:VO_0006044 a rdfs:Class ;
  rdfs:label "Pneumococcal Conjugate unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010453 .

obo:VO_0011135 a rdfs:Class ;
  rdfs:label "NA from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ;
  rdfs:comment "Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later.  The mice immunized with HA plasmid once and the NA plasmid twice survived 100% [PubMed: 19067149]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0015253 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Epaxal]" ;
  rdfs:subClassOf obo:VO_0015250 , obo:VO_0015252 .

obo:VO_0001334 a rdfs:Class ;
  rdfs:label "Abisco-100 vaccine adjuvant" ;
  rdfs:comment "A saponin vaccine adjuvant that is made from highly purified saponins." ;
  rdfs:subClassOf obo:VO_0001267 .

obo:VO_0020312 a rdfs:Class ;
  rdfs:label "Fluad Quadrivalent 2021-2022 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010423 .

obo:VO_0001728 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium Live Culture Vaccine (USDA: 19C1.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0002507 , obo:VO_0007748 .

obo:VO_0010324 a rdfs:Class ;
  rdfs:label "influenza A virus (H5N1) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0000335 a rdfs:Class ;
  rdfs:label "vaccine injection site" ;
  rdfs:comment "A vaccination site that is used for injection of a vaccine. " ;
  rdfs:subClassOf obo:VO_0003247 .

obo:BFO_0000035 a rdfs:Class ;
  rdfs:label "process boundary"@en ;
  rdfs:comment "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:VO_0002091 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002413 , obo:VO_0007748 .

obo:VO_0002479 a rdfs:Class ;
  rdfs:label "Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin" ;
  rdfs:subClassOf obo:VO_0000329 , obo:VO_0002478 .

obo:VO_0005155 a rdfs:Class ;
  rdfs:label "NVX-CoV2373 vaccine" ;
  rdfs:comment "A SARS-CoV 2 (rSARS-CoV-2) subunit vaccine made of nanoparticles composed of a trimeric full-length SARS-CoV-2 spike glycoprotein and Matrix-M1 adjuvant." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0003028 a rdfs:Class ;
  rdfs:label "human serum albumin" ;
  rdfs:comment "the serum albumin that is part of human" ;
  rdfs:subClassOf obo:VO_0000516 .

obo:VO_0004697 a rdfs:Class ;
  rdfs:label "rAd-P97c vaccine" ;
  rdfs:subClassOf obo:VO_0000329 .

obo:VO_0003986 a rdfs:Class ;
  rdfs:label "Adacel Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003984 .

obo:VO_0017247 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017246 , obo:VO_0017801 .

obo:VO_0016421 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015967 .

obo:VO_0017422 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Adt Booster] Box of 5" ;
  rdfs:subClassOf obo:VO_0017421 , obo:VO_0017424 .

obo:VO_0020527 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC] Box of 10 by Mylan" ;
  rdfs:subClassOf obo:VO_0020526 .

obo:VO_0019837 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus antigen 0.03 MG/ML Prefilled Syringe [Afluria 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003733 , obo:VO_0019836 .

obo:VO_0010276 a rdfs:Class ;
  rdfs:label "assay type datum" ;
  rdfs:comment "A measurment datum that records the type of assay used." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0017611 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017589 , obo:VO_0017610 .

obo:VO_0000862 a rdfs:Class ;
  rdfs:label "Canada" ;
  rdfs:comment "Canada is a country that exists in north America." ;
  rdfs:subClassOf obo:VO_0010632 .

obo:VO_0004657 a rdfs:Class ;
  rdfs:label "rBCG -Stx2B E. coli vaccine" ;
  rdfs:subClassOf obo:VO_0000041 .

obo:VO_0020408 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix]" ;
  rdfs:subClassOf obo:VO_0020391 .

obo:VO_0010977 a rdfs:Class ;
  rdfs:label "GNA992 (hsf)" ;
  rdfs:comment "Protective antigen [PubMed: 10710308]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0016614 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 1" ;
  rdfs:subClassOf obo:VO_0016558 .

obo:VO_0018376 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG" ;
  rdfs:subClassOf obo:VO_0003346 .

obo:VO_0003144 a rdfs:Class ;
  rdfs:label "Imuvac vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0000929 a rdfs:Class ;
  rdfs:label "polysorbate 20 vaccine stabilizer" ;
  rdfs:comment "a vaccine stabilizer that is a polysorbate 20. It encourages the suspension of one liquid in another and has mild toxicity." ;
  rdfs:subClassOf obo:VO_0000853 .

obo:VO_0010270 a rdfs:Class ;
  rdfs:label "challenge-killing interval datum" ;
  rdfs:comment "A measurment datum that  records the interval between the vaccine challenge and the sacrifice of the organism during a vaccine challenge." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0010910 a rdfs:Class ;
  rdfs:label "GP from Zaire ebolavirus" ;
  rdfs:comment "Cynomolgus macaques were immunized with DNA/rAd5 vaccines expressing ZEBOV (GP) and SEBOV glycoprotein (GP) prior to lethal challenge with BEBOV. Vaccinated subjects developed robust, antigen-specific humoral and cellular immune responses against the GP from ZEBOV as well as cellular immunity against BEBOV GP, and immunized macaques were uniformly protected against lethal challenge with BEBOV [PubMed: 20502688]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0018486 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0018442 .

obo:VO_0010470 a rdfs:Class ;
  rdfs:label "relative correlate of immune protection" ;
  rdfs:subClassOf obo:VO_0010468 .

obo:VO_0003279 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0004934 a rdfs:Class ;
  rdfs:label "human age 4 months at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0003971 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Pentacel]" ;
  rdfs:subClassOf obo:VO_0000084 .

obo:VO_0020370 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 1000000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003849 .

obo:VO_0010909 a rdfs:Class ;
  rdfs:label "TTC" ;
  rdfs:comment "The fragment C of tetanus toxin was amplified from Clostridium tetani DNA by PCR.  Immunization of mice with rTTC resulted in the production of antibodies that were able to protect mice against a challenge with tetanus toxin furthermore, rTTC in vivo appeared to be able to undergo retrograde axonal transport [PubMed: 12075415]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010775 .

obo:VO_0015191 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015275 .

obo:VO_0005092 a rdfs:Class ;
  rdfs:label "Nanocovax vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine with recombinant SARS-CoV-2 spike (S) protein and aluminum phosphate adjuvant" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0017386 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Diftavax]" ;
  rdfs:subClassOf obo:VO_0018788 .

obo:OPL_0000042 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum erythrocytic ring trophozoite stage" ;
  rdfs:comment "An erythrocytic ring trophozoite stage in the Plasmodium falciparum life cycle that occurs in erythrocytes of a human host. During this stage some Plasmodium falciparum merozoites undergo asexual reproduction cycle in erythrocytes and form young trophozoites that are referred to as \"ring form\" due to their morphology." ;
  rdfs:subClassOf obo:OPL_0000140 , obo:OPL_0000207 , obo:OPL_0000305 .

obo:OPL_0000295 a rdfs:Class ;
  rdfs:label "Plasmodium oocyst stage" ;
  rdfs:comment "An oocyst stage in the Plasmodium lifecycle that occurs on the hemocoel side of the midgut of a mosquito vector. During this stage Plasmodium ookinete invades and escapes midgut wall of mosquito and embed itself onto the exterior of the gut membrane and develop encysted zygote, called oocyst." ;
  rdfs:subClassOf obo:OPL_0000073 .

obo:VO_0007340 a rdfs:Class ;
  rdfs:label "autologous lymphoma immunoglobulin-derived scFv-chemokine DNA vaccine" ;
  rdfs:comment "A cancer vaccine that encodes macrophage inflammatory protein 3 alpha (MIP3a)-fused lymphoma idiotype in single chain format for patients with atients with Asymptomatic Phase Lymphoplasmacytic Lymphoma." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0003826 a rdfs:Class ;
  rdfs:label "Havrix Injectable Product" ;
  rdfs:subClassOf obo:VO_0000052 .

obo:VO_0004935 a rdfs:Class ;
  rdfs:label "human age 11 to 12 years at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0005491 a rdfs:Class ;
  rdfs:label "mesothelioma cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against mesothelioma cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0019742 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0016351 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:VO_0010461 a rdfs:Class ;
  rdfs:label "vaccine-induced innate immune response" ;
  rdfs:subClassOf obo:VO_0000287 .

obo:VO_0016032 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015668 , obo:VO_0015784 .

obo:VO_0016387 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015947 .

obo:VO_0018766 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0018761 .

obo:VO_0019413 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.006 MG/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Vaxelis]" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0012185 .

obo:VO_0007023 a rdfs:Class ;
  rdfs:label "Natural Killer Cells ZRx101 vaccine" ;
  rdfs:comment "A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma. (NCIT_C85466)." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0000416 a rdfs:Class ;
  rdfs:label "intravenous route" ;
  rdfs:comment "A route of administration that is located in the vein" ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0001242 a rdfs:Class ;
  rdfs:label "cholera toxin B subunit vaccine adjuvant" ;
  rdfs:comment "A cholera toxin derived vaccine adjuvant made of the B subunit of the cholera toxin from Vibrio cholerae." ;
  rdfs:subClassOf obo:VO_0001348 .

obo:VO_0012185 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae vaccine" ;
  rdfs:comment "A vaccine that protects against Haemophilus influenzae." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000661 .

obo:VO_0016491 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Mevita" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0015046 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 58 Vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003308 .

obo:VO_0000132 a rdfs:Class ;
  rdfs:label "pcDNA3 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000663 a rdfs:Class ;
  rdfs:label "SC602 vaccine" ;
  rdfs:comment "A live attenuated Shigella flexneri 2a vaccine that carries deletions of the plasmid-borne virulence gene icsA (mediating intra- and intercellular spread) and the chromosomal locus iuc (encoding aerobactin)." ;
  rdfs:subClassOf obo:VO_0000680 .

obo:NCBITaxon_2732543 a rdfs:Class ;
  rdfs:label "Hepelivirales" ;
  rdfs:subClassOf obo:NCBITaxon_2732461 .

obo:VO_0001316 a rdfs:Class ;
  rdfs:label "stearyl tyrosine vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant stearyl tyrosine is considered an \"organic equivelant\" of aluminum hydroxide." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0017965 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec] Box of 1" ;
  rdfs:subClassOf obo:VO_0017938 , obo:VO_0017949 .

obo:VO_0005372 a rdfs:Class ;
  rdfs:label "Vaxfectin vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is equimolar mixture of the cationic lipid GAP-DMORIE [(±)-N-(3-aminopropyl)-N,N-dimethyl-2,3-bis(cis-9-tetradecenyloxy)-1-propanaminium bromide)] and a neutral colipid DPyPE (1,2-diphytanoyl-sn-glydero-3-phosphoethanolamine)." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0004548 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine D1ME-VRP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0015632 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015566 , obo:VO_0015667 .

obo:VO_0020331 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003070 , obo:VO_0010431 .

obo:VO_0020504 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0010186 a rdfs:Class ;
  rdfs:label "influenza, split virus, quadrivalent, injectable, contains preservative" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0002412 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ;
  rdfs:subClassOf obo:VO_0002393 , obo:VO_0002425 .

obo:VO_0020779 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 CELLS Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0020775 .

obo:VO_0016796 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0016722 , obo:VO_0016738 , obo:VO_0016822 .

obo:VO_0004816 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0004815 .

obo:VO_0019969 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019950 .

obo:VO_0003975 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Kinrix]" ;
  rdfs:subClassOf obo:VO_0000067 .

obo:VO_0021038 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0021034 .

obo:VO_0007161 a rdfs:Class ;
  rdfs:label "Recombinant Fowlpox-PSA(L155)/TRICOM Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant fowlpox virus encoding fragment of human prostate-specific antigen (PSA), PSA:154-163 (155L), and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). Administration of this agent may induce a cytotoxic T cell response against PSA-expressing tumor cells. Dendritic cells infected with TRICOM vectors greatly enhance naive T-cell activation and peptide-specific T-cell stimulation. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0002082 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.50)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0000338 a rdfs:Class ;
  rdfs:label "Brucella melitensis bp26 deletion vaccine" ;
  rdfs:comment "A B. melitensis vaccine that is recombinant B. melitensis Rev. 1 vaccine with the bp26 deletion. It has similar vaccine efficacy to Rev. 1. Its advantage compared to Rev. 1 is that this feature of bp26 deletion promotes diagnosis. PMID:17070627." ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0005354 a rdfs:Class ;
  rdfs:label "UM-3003 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that includes UM-3003, a small molecule TLR7/8 agonist that can stimulate Th1-biased immune profile." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0011554 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 DNA vaccine tgD-VP22" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000987 .

obo:VO_0001778 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis Killed Virus Vaccine (USDA: 1525.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001486 , obo:VO_0007748 .

obo:VO_0018255 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT [RabAvert]" ;
  rdfs:subClassOf obo:VO_0000094 , obo:VO_0018268 .

obo:VO_0004300 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pIRES/HA/IL-12p35 + pIRES/NA/IL-12p40" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0011435 a rdfs:Class ;
  rdfs:label "Chlamydophila pneumoniae LcrE protein vaccine" ;
  rdfs:subClassOf obo:VO_0012173 .

obo:VO_0020875 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Preflucel] Box of 10" ;
  rdfs:subClassOf obo:VO_0020874 , obo:VO_0020884 .

obo:VO_0020521 a rdfs:Class ;
  rdfs:label "0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML Nasal Spray [Flumist] Box of 5" ;
  rdfs:subClassOf obo:VO_0020952 .

obo:VO_0015520 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML [Engerix B]" ;
  rdfs:subClassOf obo:VO_0010711 , obo:VO_0015524 .

obo:VO_0018458 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 10" ;
  rdfs:subClassOf obo:VO_0018433 , obo:VO_0018442 .

obo:VO_0011243 a rdfs:Class ;
  rdfs:label "ORF2" ;
  rdfs:comment "An open reading frame 2 plasmid (pORF2) and the capsid protein (Cap) of PCV2 were used as DNA and subunit vaccines, respectively. In FCM analysis, although pORF2 and Cap alone showed comparable efficacy in eliciting lymphoproliferative responses and Cap-specific CD4(+) T cells, pORF2 was superior to the Cap protein in triggering CD8(+) T cells. Following virus challenge, real-time PCR and histopathological analysis confirmed that only low viral DNA loads and mild microscopic lesions appeared in pORF2-immunized mice [PubMed: 18632956]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010799 .

obo:VO_0017785 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017779 .

obo:VO_0019524 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.005 MG/ML Prefilled Syringe [Recombivax]" ;
  rdfs:subClassOf obo:VO_0015489 .

obo:VO_0007331 a rdfs:Class ;
  rdfs:label "Brachyury-expressing Modified Vaccinia Ankara-TRICOM Vaccine" ;
  rdfs:comment "A cancer vaccine composed of a replication-deficient, attenuated derivative of the vaccinia virus strain Ankara expressing both a CD8+ T-cell epitope from the brachyury protein and a triad of T-cell co-stimulatory molecules (MVA Brachyury-TRICOM), with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration of the brachyury-expressing modified vaccinia Ankara (MVA)-TRICOM vaccine, the expressed brachyury protein induces specific CD8+ and CD4+ T-cell responses against brachyury-expressing tumor cells. This causes both tumor cell lysis and a decrease in the growth of brachyury-expressing tumor cells. Brachyury, a member of the T-box family of transcription factors that is overexpressed in numerous cancer cell types, is correlated with increased epithelial-mesenchymal transition (EMT), cancer resistance and cancer progression. TRICOM, a triad of three human T-cell co-stimulatory molecules, B7.1, ICAM-1 and LFA-3, enhances antigen-specific T-cell activation." ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0015534 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0016708 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0016671 , obo:VO_0016681 , obo:VO_0016719 .

obo:VO_0015827 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015622 , obo:VO_0015623 .

obo:VO_0011511 a rdfs:Class ;
  rdfs:label "Clostridium botulinum DNA vaccine pSCARSBHc" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012187 .

obo:VO_0003567 a rdfs:Class ;
  rdfs:label "PNEUMOVAX 23 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003563 .

obo:VO_0004398 a rdfs:Class ;
  rdfs:label "Lymphoma DNA vaccine V-Alpha-V-Beta-V-Beta-FrC" ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0005060 a rdfs:Class ;
  rdfs:label "pVR1020 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pVR1020.  This plasmid contains a CMV promoter and kanamycin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016043 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 250" ;
  rdfs:subClassOf obo:VO_0015669 , obo:VO_0015798 .

obo:VO_0001732 a rdfs:Class ;
  rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001019 , obo:VO_0007748 .

obo:VO_0002869 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium atpA mutant vaccine" ;
  rdfs:comment "An atpA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0002751 a rdfs:Class ;
  rdfs:label "E2 gene from Western equine encephalomyelitis virus" ;
  rdfs:comment "A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001449 .

obo:VO_0018608 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 2290000 UNT" ;
  rdfs:subClassOf obo:VO_0004822 .

obo:VO_0019198 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML / influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019677 .

obo:VO_0018742 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 8 X Oral Tablet Box of 1 by Staufen" ;
  rdfs:subClassOf obo:VO_0018741 .

obo:VO_0016268 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015923 .

obo:VO_0017257 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0017808 , obo:VO_0018769 .

obo:DOID_11076 a rdfs:Class ;
  rdfs:label "Brucella suis brucellosis"@en ;
  rdfs:comment "A brucellosis that involves an infection caused by Brucella suis [NCBITaxon:29461] in swine and humans. The disease has_symptom fever, has_symptom chills, has_symptom malaise, has_symptom diaphoresis, has_symptom arthralgia, has_symptom myalgia, has_symptom headache, has_symptom anorexia, and has_symptom fatigue."@en ;
  rdfs:subClassOf obo:DOID_11077 .

obo:VO_0016081 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015869 .

obo:VO_0004469 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine sABC encoding prM and E" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0011514 a rdfs:Class ;
  rdfs:label "Helicobacter pylori NAP protein vaccine" ;
  rdfs:subClassOf obo:VO_0012181 .

obo:VO_0018383 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML [Pneumovax 23]" ;
  rdfs:subClassOf obo:VO_0018400 .

obo:VO_0007034 a rdfs:Class ;
  rdfs:label "poly microsphere encapsulated HER2/neu oral vaccine" ;
  rdfs:comment "A cancer vaccine consisting of Her2/neu peptides incorporated into microspheres of poly (lactide-co-glycolide) (PLGA), a biodegradable polymer. Poly microsphere encapsulated HER2/neu oral vaccine has been investigated for use in immunotherapy for tumors positive for HER-2/neu, a tumor associated antigen that is overexpressed in various cancers, including breast and ovarian cancer.‚Äö√†√∂‚àö¬ß" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0018109 a rdfs:Class ;
  rdfs:label "1 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018175 .

obo:VO_0000757 a rdfs:Class ;
  rdfs:label "ISCOM vaccine adjuvant" ;
  rdfs:comment "A particulate antigen delivery system vaccine adjuvant that consists of an assembly of antigens in multimeric form and presents an antigen to induce specific immunologic responses. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines. MeSH term: D20.215.894.860.449." ;
  rdfs:subClassOf obo:VO_0001356 .

obo:VO_0019521 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.003 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0019520 .

obo:VO_0016953 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016952 .

obo:NCBITaxon_464095 a rdfs:Class ;
  rdfs:label "Picornavirales" ;
  rdfs:subClassOf obo:NCBITaxon_2732506 .

obo:VO_0020168 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018046 .

obo:VO_0007147 a rdfs:Class ;
  rdfs:label "Prostate Tumor Antigen-activated Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A dendritic cell (DC)-based cancer vaccine composed of autologous dendritic cells (DCs) activated with a prostate tumor cell lysate containing tumor-associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, the prostate tumor antigen-activated autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against prostate cancer cells expressing prostate tumor cell-specific antigens, which may result in prostate tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0017729 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 600 UNT/ML Injectable Suspension [Acel-P]" ;
  rdfs:subClassOf obo:VO_0017728 , obo:VO_0017796 .

obo:VO_0011250 a rdfs:Class ;
  rdfs:label "GIII" ;
  rdfs:comment "Mice immunized with either gII, gIII, gVI antigen or a mixture of them were challenged intraperitoneally with 8.5 x 10(3) plaque forming units of PRV. All the mice immunized with 1.5 and 4.5 micrograms of the mixture and 4.5 micrograms of the gIII antigen survived [PubMed: 1322712]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010800 .

obo:VO_0000139 a rdfs:Class ;
  rdfs:label "complete Freund's adjuvant" ;
  rdfs:comment "A Freund's emulsified oil adjuvant that contains inactivated and dried mycobacteria, usually Mycobacterium tuberculosis (the pathogenic agent of tuberculosis)." ;
  rdfs:subClassOf obo:VO_0000133 .

obo:VO_0015560 a rdfs:Class ;
  rdfs:label "1 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015555 .

obo:VO_0001931 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4560.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002354 .

obo:VO_0001556 a rdfs:Class ;
  rdfs:label "Edwardsiella ictaluri Avirulent Live Culture Vaccine (USDA: 1531.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000645 , obo:VO_0001217 , obo:VO_0001470 , obo:VO_0001521 , obo:VO_0007748 .

obo:VO_0001783 a rdfs:Class ;
  rdfs:label "Equine Rotavirus Killed Virus Vaccine (USDA: 1E15.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001496 , obo:VO_0007748 .

obo:VO_0004664 a rdfs:Class ;
  rdfs:label "rMVA-SIV-CD40L Simian immunodeficiency virus vaccine" ;
  rdfs:subClassOf obo:VO_0000751 .

obo:VO_0002743 a rdfs:Class ;
  rdfs:label "E from SARS-CoV" ;
  rdfs:comment "An E mutant is attenuated in hamsters and induces significant protection from challenge with wild type SARS" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001444 .

obo:VO_0002154 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.18)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0011265 a rdfs:Class ;
  rdfs:label "E2 envelope protein" ;
  rdfs:comment "Since the E2 amino-terminal sequence for all VEE subtype viruses is conserved, we tested the protective capacity in mice of passively transferred mAb 1A2B-10 and found it to protect from both epizootic and enzootic VEE virus challenge. Since horses are an important natural host for VEE virus, pep1-19 was used to immunize horses and was found to be immunogenic and to elicit virus-reactive antibody [PubMed: 7543231]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010774 .

obo:VO_0010421 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2020" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0002197 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotype 3, Live Marek's Disease Vector Vaccine (USDA: 1A88.R0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0015934 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015636 , obo:VO_0016035 .

obo:VO_0003319 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 15B vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003220 .

obo:VO_0003199 a rdfs:Class ;
  rdfs:label "Bordetella pertussis pertactin vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003196 .

obo:VO_0017274 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.008 MG / Bordetella pertussis 0.05 MG / diphtheria toxoid vaccine, inactivated 30 UNT / tetanus toxoid vaccine, inactivated 40 UNT Injectable Solution [Infanrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017273 .

obo:OPL_0000301 a rdfs:Class ;
  rdfs:label "Plasmodium oocyst-derived sporozoite stage" ;
  rdfs:comment "A sporozoite stage in the Plasmodium lifecycle that develops in oocyst of the mosquito midgut." ;
  rdfs:subClassOf obo:OPL_0000256 , obo:OPL_0000300 .

obo:VO_0004575 a rdfs:Class ;
  rdfs:label "Duck hepatitis virus 1 DNA vaccine pSCA/VP1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001528 .

obo:VO_0016344 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Europharma" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:VO_0003511 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0003497 .

obo:VO_0005471 a rdfs:Class ;
  rdfs:label "MAS-1 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant 30:70 (w/w) Water-in-Oil  (W/O) emulsion that stimulates a mixed Th1/Th2 response." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:IAO_0000311 a rdfs:Class ;
  rdfs:label "publication"@en ;
  rdfs:comment "A document that is the output of a publishing process."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:VO_0018446 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumopur] Box of 20" ;
  rdfs:subClassOf obo:VO_0018424 .

obo:VO_0000629 a rdfs:Class ;
  rdfs:label "Bacillus anthracis recombinant vaccine using PA domain 4" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000484 .

obo:VO_0016621 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0016601 , obo:VO_0016611 , obo:VO_0016628 .

obo:VO_0007637 a rdfs:Class ;
  rdfs:label "MAGE-A3-genetically modified lymphocyte vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0019818 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0002006 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45B9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002370 .

obo:VO_0003466 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated Injection [Vaqta]" ;
  rdfs:subClassOf obo:VO_0003462 .

obo:VO_0019495 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / meningococcal group C polysaccharide / meningococcal polysaccharide vaccine group Y Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0003192 , obo:VO_0010437 , obo:VO_0010444 , obo:VO_0020832 .

obo:VO_0011307 a rdfs:Class ;
  rdfs:label "6K" ;
  rdfs:comment """DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain [PubMed: 19923571].

Note:  The 6K protein is part of the 6K-E1 structural protein""" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010841 .

obo:VO_0007422 a rdfs:Class ;
  rdfs:label "MUC1-KLH conjugate vaccine" ;
  rdfs:comment "A peptide vaccine, containing human tumor-associated epithelial mucin (MUC1) conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with MUC1-KLH conjugate vaccine may stimulate humoral and cytotoxic T-lymphocyte (CTL) responses against tumor cells expressing the MUC1 antigen. In this vaccine, MUC1 antigen is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition. MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in an aberrant or deglycosylated form in various cancers such as those of the breast, prostate, and ovary." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0005425 , obo:VO_0005484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0001288 a rdfs:Class ;
  rdfs:label "Avridine vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is N, N-dioctadecyl-N', N'-bis(2-hydroxyethyl) propanediamine (Avridine)." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0004456 a rdfs:Class ;
  rdfs:label "Chinese Schistosoma japonicum DNA vaccine pCMV-Sjc97 encoding paramyosin" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001229 .

obo:VO_0003897 a rdfs:Class ;
  rdfs:label "Flublok 2017-2018 vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003895 .

obo:VO_0020549 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluad] Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0020548 .

obo:VO_0005071 a rdfs:Class ;
  rdfs:label "pSW3891 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pSW3891.  This plasmid contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016705 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0015113 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015111 .

obo:VO_0002740 a rdfs:Class ;
  rdfs:label "US3 from Pseudorabies virus" ;
  rdfs:comment "Researchers intranasally inoculated pigs, the natural host of this virus, with mutant PRV strains in which the genes encoding the protein kinase (US3) proteins were inactivated. After challenge infection with the virulent PRV strain NIA-3, no virus was excreted by wt PRV- and PK- mutant-immunized animals, indicating complete protective immunity" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001442 .

obo:VO_0001675 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.14)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001488 , obo:VO_0007748 .

obo:VO_0020261 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0018553 a rdfs:Class ;
  rdfs:label "0.5 ML Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015055 , obo:VO_0018807 .

obo:VO_0017001 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tet Aktiv]" ;
  rdfs:subClassOf obo:VO_0016995 , obo:VO_0017487 .

obo:VO_0017374 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Diftavax]" ;
  rdfs:subClassOf obo:VO_0018786 .

obo:VO_0002732 a rdfs:Class ;
  rdfs:label "GP5 protein from Porcine respiratory and reproductive syndrome virus" ;
  rdfs:comment "A mutation in the GP5 protein attenuates HP-PRRSV in piglets. This mutant (HuN4-F112) induces protection against challenge with wild type HP-PRRSV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001441 .

obo:VO_0002457 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis vaccine" ;
  rdfs:subClassOf obo:VO_0001222 , obo:VO_0001502 .

obo:VO_0004624 a rdfs:Class ;
  rdfs:label "FPV-LT vaccine" ;
  rdfs:subClassOf obo:VO_0001488 .

obo:VO_0017150 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 50 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017149 .

obo:VO_0007102 a rdfs:Class ;
  rdfs:label "recombinant human Hsp110-gp100 chaperone complex vaccine" ;
  rdfs:comment "A recombinant chaperone-peptide complex-based vaccine composed of a complex between heat shock protein hsp110 and the human melanoma-associated antigen gp100, with potential antineoplastic activity. Upon vaccination, recombinant hsp110-gp100 chaperone complex activates the immune system to exert a cytotoxic T cell immune response and antigen-specific interferon-gamma production against gp100-overexpressing cancer cells. Gp100, is overexpressed in a variety of cancer cell types. Hsp110, binds to and chaperones full-length proteins during heat shock; as an immunoadjuvant it is able to enhance an immune response against antigen(s) and stimulate T-lymphocyte activation." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0007175 a rdfs:Class ;
  rdfs:label "VHL-42: 65-76(V74G) Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine consisting of amino acids 65 through 76 derived from the tumor suppressor protein Von Hippel-Lindau (VHL) with a glycine substitution at position 74. As a cancer vaccine, VHL-59: 65-76(V74G) may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0004615 a rdfs:Class ;
  rdfs:label "pcDNA3-MCC/ST vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0010110 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii RACK1" ;
  rdfs:comment "A RACK1 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0018280 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Prefilled Syringe [VACCIN RABIQUE INACTIVE MERIEUX]" ;
  rdfs:subClassOf obo:VO_0018260 , obo:VO_0018267 , obo:VO_0018289 .

obo:VO_0017018 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 50 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0017017 .

obo:VO_0001422 a rdfs:Class ;
  rdfs:label "Salmonella Enteritidis gene" ;
  rdfs:comment "A bacterial gene that is from Salmonella Enteritidis." ;
  rdfs:subClassOf obo:VO_0000168 .

obo:VO_0017865 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0017493 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 2" ;
  rdfs:subClassOf obo:VO_0017489 , obo:VO_0017499 .

obo:VO_0002739 a rdfs:Class ;
  rdfs:label "UL50 from Pseudorabies virus" ;
  rdfs:comment "A UL50 mutant is attenuated in pseudorabies virus and induces significant protection in pigs from challenge with the highly virulent NIA-3 strain of PrV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001442 .

obo:VO_0018169 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution [Priorix] Box of 20" ;
  rdfs:subClassOf obo:VO_0018167 , obo:VO_0018171 .

obo:VO_0002802 a rdfs:Class ;
  rdfs:label "Bordetella bronchiseptica aroA/trpE mutant vaccine" ;
  rdfs:comment "Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract" ;
  rdfs:subClassOf obo:VO_0000394 .

obo:VO_0004387 a rdfs:Class ;
  rdfs:label "Marburg virus DNA vaccine MARV GP encoding GP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012163 .

obo:VO_0018513 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 10 by European" ;
  rdfs:subClassOf obo:VO_0018505 .

obo:VO_0021169 a rdfs:Class ;
  rdfs:label "0.25 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0019987 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Flucelvax 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019974 .

obo:VO_0017071 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Tetamun] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017068 .

obo:VO_0001121 a rdfs:Class ;
  rdfs:label "rhabdovirus-based vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a rhabdovirus-based viral strain as the vaccine vector" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0002017 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Modified Live Virus Vaccine (USDA: 1931.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002374 .

obo:VO_0010869 a rdfs:Class ;
  rdfs:label "LASVsSgp2 glycoprotein" ;
  rdfs:comment "HLA-A*0201 mice immunized with either GPC(42-50) from LASVsSgp2 glycoprotein or GPC(60-68) were protected against challenge with a recombinant vaccinia virus that expressed LASV GPC [PubMed: 16912286]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010763 .

obo:VO_0001305 a rdfs:Class ;
  rdfs:label "D-Murapalmitine vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that includes an MDP analog called D-Murapalmitine." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0016347 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:VO_0003516 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0003514 .

obo:OBI_0200201 a rdfs:Class ;
  rdfs:label "ANOVA" ;
  rdfs:comment "A statistical hypothesis test in which the means of several groups are all equal."@en ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:VO_0011030 a rdfs:Class ;
  rdfs:label "FhaB" ;
  rdfs:comment "A combination of the 69-kDa outer membrane protein and filamentous hemagglutinin (fhaB), both isolated from lymphocytosis promoting factor (LPF; pertussis toxin) minus mutants of Bordetella pertussis, is protective in the mouse intracerebral challenge potency (Kendrick) test [PubMed: 2056199]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:VO_0015956 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015730 , obo:VO_0015736 , obo:VO_0016046 .

obo:VO_0003107 a rdfs:Class ;
  rdfs:label "Rabivac vaccine" ;
  rdfs:comment "A human diploid cell vaccine against rabies, a viral infectious disease." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0000712 , obo:VO_0010448 .

obo:VO_0015913 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Fendrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015628 , obo:VO_0015766 .

obo:VO_0018731 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Intramuscular Solution [Typherix]" ;
  rdfs:subClassOf obo:VO_0018718 , obo:VO_0018730 .

obo:CHEBI_53424 a rdfs:Class ;
  rdfs:label "polysorbate 20" ;
  rdfs:comment "A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0001351 a rdfs:Class ;
  rdfs:label "threonyl muramyl dipeptide (TMDP) vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is threonyl muramyl dipeptide (TMDP)." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0020811 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000743 .

obo:VO_0004743 a rdfs:Class ;
  rdfs:label "rFPV-AI-H5A-IL6 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0016070 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 50 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015867 .

obo:VO_0006089 a rdfs:Class ;
  rdfs:label "Venezuelan equine encephalitis inactivated" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000712 , obo:VO_0001499 .

obo:VO_0019507 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML Injection [Vaqta]" ;
  rdfs:subClassOf obo:VO_0018870 , obo:VO_0019506 , obo:VO_0019511 .

obo:VO_0004431 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine TA2M encoding tyrosinase peptides" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0010821 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:CHEBI_52071 a rdfs:Class ;
  rdfs:label "dextran" ;
  rdfs:comment "A (1->6)-alpha-D-glucan which has extra branching consisting of (1->2), (1->3) or (1->4) linkages." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0007500 a rdfs:Class ;
  rdfs:label "CAR G36-PDL1 vaccine" ;
  rdfs:comment "A cancer vaccine made with chimeric antigen receptor (CAR) T cells that can be used to treat solid tumors. These CAR-T cells are engineered to target carbonic anhydrase IX (CAIX) to secrete anti-PD-L1 monoclonal antibody (mAb), termed immune-restoring (IR) CAR G36-PDL1. The T cells can be used to treat clear cell renal cell carcinoma (ccRCC) with reconstituted human leukocyte antigen (HLA) partially matched human leukocytes derived from fetal CD34+ hematopoietic stem cells (HSCs) and bearing human ccRCC skrc-59 cells under the kidney capsule. The cells can restore active antitumor immunity by promoting tumor-killing cytotoxicity, reducing immunosuppressive cell components such as M2 macrophages and exhausted CD8+ T cells, and enhancing T follicular helper (Tfh)-B cell crosstalk." ;
  rdfs:subClassOf obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0002580 a rdfs:Class ;
  rdfs:label "aroC from Edwardsiella tarda" ;
  rdfs:comment "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001413 .

obo:VO_0020923 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0003502 , obo:VO_0004914 .

obo:VO_0002497 a rdfs:Class ;
  rdfs:label "influenza vaccine (inactivated, adjuvanted)" ;
  rdfs:comment """created according to 
WHO Technical Report Series, No. 927, 2005
Annex 3
Recommendations for the production and control of influenza vaccine (inactivated)""" ;
  rdfs:subClassOf obo:VO_0001176 .

obo:VO_0000308 a rdfs:Class ;
  rdfs:label "Francisella tularensis vaccine LVS LPS" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0001993 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002362 .

obo:VO_0019449 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 25 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0002954 a rdfs:Class ;
  rdfs:label "Classical swine fever virus E2 mutant vaccine" ;
  rdfs:comment "A E2 mutant in Classical swine fever virus is attenuated and provides protection in pigs after oronasal vaccination (not intradermal vaccination) against lethal challenge dose of CSFV strain Eystrup" ;
  rdfs:subClassOf obo:VO_0001012 .

obo:VO_0001470 a rdfs:Class ;
  rdfs:label "catfish vaccine" ;
  rdfs:comment "Vaccine that used for immunizing catfish." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001462 .

obo:VO_0018394 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe [Pneumovax II]" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0002093 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002413 , obo:VO_0007748 .

obo:VO_0002378 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0000568 , obo:VO_0001466 , obo:VO_0001501 .

obo:VO_0004649 a rdfs:Class ;
  rdfs:label "RB51-MIC3/GRA6/MIC1/SRS2 vaccine" ;
  rdfs:subClassOf obo:VO_0001065 .

obo:VO_0002899 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium IppB/msbB mutant vaccine" ;
  rdfs:comment "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" .

obo:VO_0020437 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020406 .

obo:VO_0020796 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 CELLS Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020794 , obo:VO_0020806 .

obo:VO_0002464 a rdfs:Class ;
  rdfs:label "Parvovirus-Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-CanicolaGrippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002465 .

obo:VO_0002230 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002487 , obo:VO_0007748 .

obo:VO_0017321 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Act-HIB DTP]" ;
  rdfs:subClassOf obo:VO_0017320 .

obo:VO_0018194 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus vaccine Injectable Suspension [M.M.R. VaxPro]" ;
  rdfs:subClassOf obo:VO_0018193 .

obo:VO_0007496 a rdfs:Class ;
  rdfs:label "HLA-A2-binding TYR/MART-1/gp100 multipeptide-pulsed autologous dendritic cell vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted melanoma-associated antigen peptides tyrosinase (TYR), MART-1(melanoma antigen recognized by T-cells) and melanoma antigen glycoprotein 100 (gp100), with potential immunomodulating and antineoplastic activity. Upon vaccination, HLA-A2-binding TYR/MART-1/gp100 multipeptide-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount an anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against Tyr-, MART-1 and gp100-expressing cancer cells, resulting in tumor cell lysis. HLA-A2 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A2 may improve antigenic peptide immunogenicity." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0004703 a rdfs:Class ;
  rdfs:label "Ty21a-O-Ps (Shigella dysenteriae )" ;
  rdfs:subClassOf obo:VO_0000769 .

obo:VO_0007682 a rdfs:Class ;
  rdfs:label "KLH and tumor lysate pulsed DC vaccine" ;
  rdfs:comment "A cancer vaccine made with dendritic cells pulsed with KLH and tumor lysate for patients with neuroblastoma." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0017488 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tet Aktiv] Box of 100" ;
  rdfs:subClassOf obo:VO_0017487 , obo:VO_0017498 .

obo:VO_0020005 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML Prefilled Syringe [Fluzone High-Dose 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020484 .

obo:VO_0018300 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT Injection [Imovax]" ;
  rdfs:subClassOf obo:VO_0018258 , obo:VO_0018307 , obo:VO_0020181 .

obo:OGG_3000885596 a rdfs:Class ;
  rdfs:label "panD" ;
  rdfs:comment "Probable aspartate 1-decarboxylase precursor PanD (aspartate alpha-decarboxylase)" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0020604 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 10 by Evans Vaccines" ;
  rdfs:subClassOf obo:VO_0020603 .

obo:VO_0001985 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002360 .

obo:VO_0020645 a rdfs:Class ;
  rdfs:label "1 ML BCG, live, Connaught strain 20000 UNT/ML Injectable Solution by AJ Vaccines" ;
  rdfs:subClassOf obo:VO_0020642 .

obo:VO_0016666 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by Europharma" ;
  rdfs:subClassOf obo:VO_0016626 .

obo:VO_0016857 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016805 .

obo:VO_0016636 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0016621 .

obo:VO_0021142 a rdfs:Class ;
  rdfs:label "influenza virus vaccine 2022-2023 (quadrivalent - Austria/Darwin/Phuket/Victoria) Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0003556 a rdfs:Class ;
  rdfs:label "Lactobacillales vaccine" ;
  rdfs:subClassOf obo:VO_0003554 .

obo:VO_0010813 a rdfs:Class ;
  rdfs:label "Yersinia ruckeri protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0017898 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015067 .

obo:NCBITaxon_8835 a rdfs:Class ;
  rdfs:label "Anas" ;
  rdfs:subClassOf obo:NCBITaxon_1549675 .

obo:VO_0020969 a rdfs:Class ;
  rdfs:label "Influenza Virus Fragmented, Inactivated, Strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain A / South Australia / 55/2014 Ivr-175" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0010298 , obo:VO_0010415 .

obo:VO_0002397 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2 Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ;
  rdfs:subClassOf obo:VO_0001490 , obo:VO_0002391 .

obo:VO_0003993 a rdfs:Class ;
  rdfs:label "INFANRIX vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003958 .

obo:VO_0002423 a rdfs:Class ;
  rdfs:label "equine EEV and WEV encephalomyelitis-influenza-West Nile virus vaccine-tetanus toxoid" ;
  rdfs:subClassOf obo:VO_0000752 , obo:VO_0002422 .

obo:VO_0010342 a rdfs:Class ;
  rdfs:label "DENGVAXIA vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0000725 , obo:VO_0001220 .

obo:VO_0011457 a rdfs:Class ;
  rdfs:label "Dengue subunit E protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000725 .

obo:VO_0020773 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 CELLS" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0019465 .

obo:VO_0004281 a rdfs:Class ;
  rdfs:label "Fluad vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0016964 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Adt Booster]" ;
  rdfs:subClassOf obo:VO_0016963 , obo:VO_0017421 .

obo:VO_0002461 a rdfs:Class ;
  rdfs:label "Parvovirus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0001456 , obo:VO_0002462 .

obo:VO_0003082 a rdfs:Class ;
  rdfs:label "Vaxchora vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000763 , obo:VO_0006004 , obo:VO_0010312 .

obo:NCBITaxon_149539 a rdfs:Class ;
  rdfs:label "Salmonella enterica subsp. enterica serovar Enteritidis" ;
  rdfs:subClassOf obo:NCBITaxon_59201 .

obo:VO_0018360 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003341 .

obo:VO_0016239 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Fendrix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015908 .

obo:VO_0004019 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding HA from influenza B virus (B/Ibaraki/2/85)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0018158 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 25" ;
  rdfs:subClassOf obo:VO_0018143 .

obo:VO_0011463 a rdfs:Class ;
  rdfs:label "Coccidioides immitis subunit URE protein vaccine" ;
  rdfs:comment "a Coccidioides vaccine that contains C. immitis subunit URE protein" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012179 .

obo:VO_0011098 a rdfs:Class ;
  rdfs:label "US5" ;
  rdfs:comment "BALB/c mice receiving a glycoprotein D1 (gD1, US5) DNA vaccine alone were 80% protected against a subsequent HSV-1 challenge.  Results also indicate that the administration of NLX as an adjuvant improved protective immunity against HSV-1 [PubMed: 19174474]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010834 .

obo:NCBITaxon_5690 a rdfs:Class ;
  rdfs:label "Trypanosoma" ;
  rdfs:subClassOf obo:NCBITaxon_5654 .

obo:VO_0019703 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0015856 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [HBvaxPRO] by Sanofi" ;
  rdfs:subClassOf obo:VO_0015650 .

obo:VO_0011088 a rdfs:Class ;
  rdfs:label "PUUVsSgp1" ;
  rdfs:comment "To investigate the ability of recombinant N (rN, nucleocapsid proteins) from different hantaviruses to elicit cross-protection, we immunized bank voles with rN from Puumala (PUUV), Topografov (TOPV), Andes (ANDV), and Dobrava (DOBV) viruses and subsequently challenged them with PUUV. All animals immunized with PUUV (PUUVsSgp1) and TOPV rN were completely protected [PubMed: 12050380]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010768 .

obo:NCBITaxon_10537 a rdfs:Class ;
  rdfs:label "Canine mastadenovirus A" ;
  rdfs:subClassOf obo:NCBITaxon_10509 .

obo:VO_0019677 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML / influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0015194 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension [Havrix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015193 .

obo:VO_0002565 a rdfs:Class ;
  rdfs:label "mucR from B. melitensis" ;
  rdfs:comment "A mucR mutant has a significantly reduced degree of colonization in mice and protects against wild type B. melitensis 16M" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001400 .

obo:VO_0003606 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010309 , obo:VO_0010415 .

obo:VO_0003527 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0003526 .

obo:VO_0020816 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0018536 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 12 BAU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018633 .

obo:VO_0019242 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hawaii/70/2019 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Minnesota/41/2019 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0016452 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Mevita" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0012163 a rdfs:Class ;
  rdfs:label "Marburg Virus vaccine" ;
  rdfs:comment "A vaccine that protects against Marburg Virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0010240 a rdfs:Class ;
  rdfs:label "host adverse event variable" ;
  rdfs:comment "A variable representing the presence of host adverse events from the vaccination process." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0003745 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0001817 , obo:VO_0010433 .

obo:VO_0002649 a rdfs:Class ;
  rdfs:label "obsolete msbB from Salmonella spp." ;
  rdfs:comment "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" .

obo:VO_0001114 a rdfs:Class ;
  rdfs:label "Bordetella avium vaccine" ;
  rdfs:comment "Bordetella bacterial vaccine against infection of B. avium" ;
  rdfs:subClassOf obo:VO_0000587 .

obo:VO_0021027 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 PFU/ML Injectable Suspension [Zostavax]" ;
  rdfs:subClassOf obo:VO_0021025 , obo:VO_0021026 , obo:VO_0021045 .

obo:VO_0018897 a rdfs:Class ;
  rdfs:label "influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:VO_0000045 a rdfs:Class ;
  rdfs:label "Fluarix vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0007590 a rdfs:Class ;
  rdfs:label "Biolistic DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0017423 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Adt Vaccine]" ;
  rdfs:subClassOf obo:VO_0017384 , obo:VO_0017420 .

obo:VO_0016131 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015881 .

obo:VO_0018781 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010323 , obo:VO_0010437 .

obo:VO_0010088 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii CST2" ;
  rdfs:comment "A CST2 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0004871 a rdfs:Class ;
  rdfs:label "HUMAN ADENOVIRUS B SEROTYPE 7 STRAIN 55142" ;
  rdfs:comment "CUI: C4083103" ;
  rdfs:subClassOf obo:NCBITaxon_10508 .

obo:VO_0000085 a rdfs:Class ;
  rdfs:label "Plague vaccine by Greer Laboratories Inc" ;
  rdfs:comment "Product Name: Plague Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010482 .

obo:VO_0018902 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0003097 a rdfs:Class ;
  rdfs:label "Rotashield vaccine" ;
  rdfs:comment "A rotavirus vaccine against severe diarrheal disease." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000641 , obo:VO_0001220 , obo:VO_0010449 .

obo:VO_0001964 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4465.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002364 .

obo:VO_0004535 a rdfs:Class ;
  rdfs:label "IBV DNA vaccine pVAX1-16S1/M/N" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001502 .

obo:VO_0017196 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0017188 , obo:VO_0017636 .

obo:VO_0017684 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0005416 a rdfs:Class ;
  rdfs:label "mRNA-1273.529 vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA booster vaccine by Moderna that targets the Omicron variant" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0004650 a rdfs:Class ;
  rdfs:label "BPZE1- FHA (H1N1/PR8 influenza A virus) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0020355 a rdfs:Class ;
  rdfs:label "Fluvirin 2010-2011 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000046 , obo:VO_0000578 , obo:VO_0010426 .

obo:VO_0004715 a rdfs:Class ;
  rdfs:label "rLAG- PA-Dcpep vaccine" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0020510 a rdfs:Class ;
  rdfs:label "hepatitis A virus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0002858 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis metH/siaD mutant vaccine" ;
  rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0016004 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 20" ;
  rdfs:subClassOf obo:VO_0003424 .

obo:VO_0003454 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 13.4 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0010929 a rdfs:Class ;
  rdfs:label "VP35 from Marburg Virus" ;
  rdfs:comment "Guinea pigs were vaccinated with recombinant VEE replicons (packaged into VEE-like particles), inoculated with MBGV, and evaluated for viremia and survival after challenge with typical MGBV disease.  Results indicated that VP35 afforded incomplete protection [PubMed: 9813200 ]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010769 .

obo:VO_0016442 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Waymade" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0017054 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] Box of 25 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017053 .

obo:VO_0005405 a rdfs:Class ;
  rdfs:label "AAHI-SC2 vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by ImmunityBio, Inc." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0017185 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017628 .

obo:VO_0018252 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0005397 a rdfs:Class ;
  rdfs:label "GRT-R912 vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by Gritstone Bio, Inc." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0020221 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.1 MG/ML Injectable Suspension [Comirnaty]" ;
  rdfs:subClassOf obo:VO_0020219 , obo:VO_0020220 .

obo:VO_0018586 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML Oral Suspension [Rotarix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018585 .

obo:VO_0015183 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0015180 , obo:VO_0015189 , obo:VO_0015270 .

obo:VO_0002971 a rdfs:Class ;
  rdfs:label "Herpes simplex virus 1 gH mutant vaccine" ;
  rdfs:comment "A gH mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1" ;
  rdfs:subClassOf obo:VO_0000958 .

obo:VO_0019234 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Delaware/39/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Nebraska/14/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0018133 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0020706 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] Box of 6" ;
  rdfs:subClassOf obo:VO_0020703 , obo:VO_0020709 .

obo:VO_0018018 a rdfs:Class ;
  rdfs:label "Poliomyelitis Virus Type 2 (Sabin Strain (P712, Ch, 2ab)) Live Attenuated Oral Vaccine" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0003167 .

obo:DOID_2914 a rdfs:Class ;
  rdfs:label "immune system disease"@en ;
  rdfs:comment "A disease of anatomical entity that is located_in the immune system."@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:VO_0004675 a rdfs:Class ;
  rdfs:label "SL3262- UreA and UreB vaccine" ;
  rdfs:subClassOf obo:VO_0012181 .

obo:VO_0020555 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluarix] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020554 .

obo:VO_0003961 a rdfs:Class ;
  rdfs:label "ChAd63-KH vaccine" ;
  rdfs:comment "replication defective simian adenoviral vector expressing KH, a self-cleaving polyprotein comprising L. donovani KMP-11 and HASPB" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001142 .

obo:VO_0015340 a rdfs:Class ;
  rdfs:label "Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML Injection [Vivaxim]" ;
  rdfs:subClassOf obo:VO_0015338 , obo:VO_0015339 .

obo:VO_0004051 a rdfs:Class ;
  rdfs:label "Streptococcus agalactiae Rib protein vaccine" ;
  rdfs:subClassOf obo:VO_0001375 .

obo:VO_0004270 a rdfs:Class ;
  rdfs:label "Bacillus anthracis PA protein vaccine with TMDP" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0004661 a rdfs:Class ;
  rdfs:label "rVSV- SEBOV-GP and -VP40 vaccine" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:NCBITaxon_186537 a rdfs:Class ;
  rdfs:label "Marburgvirus" ;
  rdfs:subClassOf obo:NCBITaxon_11266 .

obo:VO_0020398 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0020383 .

obo:VO_0016490 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0019301 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019983 .

obo:VO_0017173 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017172 .

obo:VO_0001582 a rdfs:Class ;
  rdfs:label "Salmonella Dublin Live Culture Vaccine (USDA: 19D1.R0)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000768 , obo:VO_0000813 , obo:VO_0001217 .

obo:VO_0016823 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0016733 , obo:VO_0016772 .

obo:VO_0018388 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Injectable Solution [Pnu-Imune]" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:VO_0017565 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] Box of 20" ;
  rdfs:subClassOf obo:VO_0017563 , obo:VO_0017578 .

obo:VO_0005343 a rdfs:Class ;
  rdfs:label "COVID-19 subunit vaccine by PT Bio Farma" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine by PT Bio Farma" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0001411 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei gene" ;
  rdfs:comment "A bacterial gene that is from Burkholderia pseudomallei." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0001682 a rdfs:Class ;
  rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1622.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000985 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0000352 a rdfs:Class ;
  rdfs:label "Megan Egg vaccine" ;
  rdfs:comment "Megan Egg is a Salmonella vaccine that that consists of a double gene-deleted S. enterica serovar Typhimurium strain and is formulated fro immunization of pullets. Megan Egg contains the same Megan Vac1 organism but Megan Vac1 is used for younger birds (broilers)." ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000768 .

obo:VO_0010336 a rdfs:Class ;
  rdfs:label "AFLURIA QUADRIVALENT SOUTHERN HEMISPHERE vaccine" ;
  rdfs:subClassOf obo:VO_0001817 .

obo:VO_0001250 a rdfs:Class ;
  rdfs:label "monophosphoryl lipid A vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant derived from the lipopolysaccharide (LPS) of Salmonella minnesota R595." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0001388 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine encoding G4" ;
  rdfs:comment "A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi G4 protein." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0000792 a rdfs:Class ;
  rdfs:label "mouse gene" ;
  rdfs:subClassOf obo:OGG_0000000002 .

obo:VO_0020805 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain Injectable Solution [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020804 .

obo:VO_0003210 a rdfs:Class ;
  rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003200 .

obo:VO_0007485 a rdfs:Class ;
  rdfs:label "gp100 Vaccinia vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant vaccinia virus encoding the gp100 melanoma-melanocyte antigen. gp100 human antigen is a wild-type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0010125 a rdfs:Class ;
  rdfs:label "Staphylococcus bacteriophage lysate" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000770 .

obo:VO_0019666 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Flublok Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020324 .

obo:VO_0011125 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Goose/Guangdong/1/96(H5N1))" ;
  rdfs:comment "Results indicated that two doses of 10 microg of pCAGGoptiHA derived from Influenza A virus (A/Goose/Guangdong/1/96(H5N1)) could induce complete protection in chickens against H5 lethal virus challenge [PubMed: 17451817]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:NCBITaxon_11095 a rdfs:Class ;
  rdfs:label "Pestivirus" ;
  rdfs:subClassOf obo:NCBITaxon_11050 .

obo:VO_0003335 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0007229 a rdfs:Class ;
  rdfs:label "Allogeneic Melanoma Vaccine AGI-101H" ;
  rdfs:comment "A cancer vaccine derived from two gentically modified human melanoma cell lines with potential antineoplastic activity. Allogeneic melanoma vaccine AGI-101H consists of a 1:1 mixture of cells from two genetically modified human melanoma cell lines, designated as Mich1H6 and Mich2H6, that have been gamma-irradiated to render the cells non-proliferative. Upon administration, this vaccine may stimulate a cytotoxic immune response against melanoma tumor cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0007455 a rdfs:Class ;
  rdfs:label "human papillomavirus  E6/E7 DNA vaccine GX-188E" ;
  rdfs:comment "A therapeutic DNA vaccine encoding the E6/E7 fusion protein of human papillomavirus (HPV) subtypes 16 and 18, plus the immune-enhancer, Fms-like tyrosine kinase-3 ligand (FLT3L), with potential immunostimulating and antineoplastic activities. DNA vaccine GX-188E is administered using a proprietary delivery system that electroporates the vaccine into cervical cells. Expression of the E6/E7 fusion product may elicit a cytotoxic T-lymphocyte (CTL) response against cervical cancer cells expressing E6 and E7 oncoproteins, resulting in tumor cell lysis. FLT3L is a ligand for the FLT3 tyrosine kinase receptor, which upon activation stimulates the proliferation of hematopoietic progenitor cells. HPV type 16 and 18 are the most common HPV types involved in cervical carcinogenesis" ;
  rdfs:subClassOf obo:VO_0000667 , obo:VO_0007656 , obo:VO_0007660 .

obo:VO_0006011 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine pediatric/adolescent dosage 3 dose schedule" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 .

obo:VO_0003919 a rdfs:Class ;
  rdfs:label "FLUAD 2015-2016 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003918 .

obo:DOID_0050687 a rdfs:Class ;
  rdfs:label "cell type cancer"@en ;
  rdfs:comment "A cancer that is classified by the type of cell from which it is derived."@en ;
  rdfs:subClassOf obo:DOID_162 .

obo:VO_0020958 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 UNT/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 .

obo:VO_0020024 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injectable Suspension [Fluvirin 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020019 , obo:VO_0020355 .

obo:VO_0001711 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0002885 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium guaBA/clpP mutant vaccine" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:OBI_0000686 a rdfs:Class ;
  rdfs:label "material combination objective" ;
  rdfs:comment "is an objective to obtain an output material that contains several input materials."@en ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:VO_0016356 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Europharma" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:VO_0016402 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 3 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015960 , obo:VO_0015966 .

obo:VO_0000233 a rdfs:Class ;
  rdfs:label "life-threatening reaction to previous vaccination" ;
  rdfs:subClassOf obo:VO_0000227 .

obo:VO_0018688 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0018686 , obo:VO_0018687 , obo:VO_0020188 .

obo:VO_0019779 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010433 .

obo:VO_0007078 a rdfs:Class ;
  rdfs:label "Recombinant Vaccinia-CEA Vaccine" ;
  rdfs:comment "A recombinant vaccinia virus encoding carcinoembryonic antigen (CEA). CEA is overexpressed in several cancer cell types, including gastrointestinal, breast, and non-small cell lung cancers. Attenuated vaccinia virus is a highly effective immunizing agent that evokes both humoral and cell-mediated responses. Vaccination with this agent may evoke a cytotoxic immune response to CEA-expressing cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005429 , obo:VO_0007657 .

obo:VO_0002554 a rdfs:Class ;
  rdfs:label "cyaA from Bordetella bronchiseptica" ;
  rdfs:comment "A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 x 105 CFU of RB50, the B. Bronchiseptica parent strain" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001407 .

obo:VO_0015207 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015206 , obo:VO_0015301 .

obo:VO_0001846 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Modified Live & Killed Virus Vaccine (USDA: 15B9.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0002433 , obo:VO_0007748 .

obo:VO_0019187 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0020303 .

obo:VO_0005188 a rdfs:Class ;
  rdfs:label "Turkovac vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Health Institutes of Turkey" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0000389 a rdfs:Class ;
  rdfs:label "Feline panleukopenia virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Feline panleukopenia virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 , obo:VO_0001465 .

obo:VO_0016316 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015931 .

obo:VO_0016896 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.025 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017269 .

obo:VO_0018910 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/11/2021 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:VO_0011424 a rdfs:Class ;
  rdfs:label "Chlamydophila pneumoniae DNA vaccine encoding PknD" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012173 .

obo:VO_0003633 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016-2017 Injectable Suspension" ;
  rdfs:comment "RXN STRENGTH: 0.03 MG/ML (expressed as influenza A virus A/California/7/2009 (H1N1) antigen) / 0.03 MG/ML (expressed as influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen) / 0.03 MG/ML (expressed as influenza B virus B/Brisbane/60/2008 antigen) / 0.03 MG/ML (expressed as influenza B virus B/Phuket/3073/2013 antigen)" ;
  rdfs:subClassOf obo:VO_0003628 .

obo:VO_0011238 a rdfs:Class ;
  rdfs:label "GB" ;
  rdfs:comment "Recombinant adenovirus expressing gB (rAd-gB) was found to induce effective protective immunity against a virulent viral infection, regardless of whether it was administered via the muscular or systemic route [PubMed: 19116444]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010800 .

obo:VO_0010802 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:DOID_0080176 a rdfs:Class ;
  rdfs:label "meningococcal meningitis"@en ;
  rdfs:comment "A bacterial meningitis that has_material_basis_in Neisseria meningitidis infection."@en ;
  rdfs:subClassOf obo:DOID_9470 .

obo:VO_0006074 a rdfs:Class ;
  rdfs:label "SARS-COV-2 COVID-19 Viral Vector Non-replicating Non-US Vaccine Product (CONVIDECIA) CanSino Biological Inc./Beijing Institute of Biotechnology" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005267 .

obo:VO_0021090 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Kinrix]" ;
  rdfs:subClassOf obo:VO_0000067 .

obo:VO_0010779 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:VO_0007555 a rdfs:Class ;
  rdfs:label "HLA-A*0201-Restricted URLC10-VEGFR1-VEGFR2 multipeptide vaccine" ;
  rdfs:comment "A cancer vaccine containing three HLA-A0201-restricted peptide epitopes with potential immunostimulatory, antiangiogenic, and antitumor activities. Vaccine peptide epitopes are derived from the tumor associated antigen (TAA) URLC (up-regulated in lung cancer 10) and vascular endothelial growth factor receptors (VEGFR) 1 and 2. Upon administration, HLA-A0201-restricted URLC10-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against URLC10-expressing tumor cells and the tumor microvasculature expressing VEGFR 1 and 2 peptides; this may result in tumor cell lysis, the inhibition of tumor angiogenesis, and decreased tumor growth. HLA-A0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0000349 a rdfs:Class ;
  rdfs:label "influenza A (H1N1) 2009 Monovalent vaccine (MedImmune LLC)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001178 , obo:VO_0003211 , obo:VO_0010415 .

obo:VO_0019402 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 600 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017806 , obo:VO_0019401 .

obo:VO_0001406 a rdfs:Class ;
  rdfs:label "Aeromonas hydrophila gene" ;
  rdfs:comment "A bacterial gene that is from Aeromonas hydrophila." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0003246 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 8 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0011119 a rdfs:Class ;
  rdfs:label "M2 from Influenza A virus (A/Puerto Rico/8/34(H1N1))" ;
  rdfs:comment "A targeted fusion protein based on the CTA1-DD adjuvant and containing tandem repeats of the matrix protein 2 (M2e) ectodomain epitope derived from Influenza A virus (A/Puerto Rico/8/34(H1N1)), CTA1-3M2e-DD, confers strong protective immunity against a potentially lethal challenge infection with influenza virus in mice. The formulation was highly effective for mucosal immunizations and promoted high M2e-specific serum IgG and mucosal IgA antibody titers and an hitherto unknown anti-M2e CD4 T cell immunity [PubMed: 18243429]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0004911 a rdfs:Class ;
  rdfs:label "PfSPZ-Cvac vaccine" ;
  rdfs:comment "The fully infectious PfSPZ are attenuated in vivo by concomitant administration of an anti-malarial drug (chloroquine). Chloroquine kills disease-associated blood stages but does not affect pre-erythrocytic (sporozoite or liver) stages, which are exposed to the host's immune system. Sporozoites-induced protection is mediated by immunity against pre-erythrocytic stages." ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0004582 a rdfs:Class ;
  rdfs:label "IBV DNA vaccine pVAX-S1 with GM-CSF adjuvant" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001502 .

obo:VO_0018347 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003337 .

obo:VO_0000127 a rdfs:Class ;
  rdfs:label "aluminum hydroxide vaccine adjuvant" ;
  rdfs:comment "An aluminum vaccine adjuvant that contains aluminum hydroxide." ;
  rdfs:subClassOf obo:VO_0000884 .

obo:VO_0003313 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 11A vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003217 .

obo:NCBITaxon_5659 a rdfs:Class ;
  rdfs:label "Leishmania amazonensis" ;
  rdfs:subClassOf obo:NCBITaxon_38568 .

obo:VO_0007291 a rdfs:Class ;
  rdfs:label "Autologous Dinitrophenyl-Modified Ovarian Cancer Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous ovarian cancer cell peptide antigens conjugated to the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of autologous dinitrophenyl-modified ovarian cancer vaccine may induce a cytotoxic T-lymphocyte (CTL) response against ovarian cancer cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0016084 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015869 .

obo:VO_0001791 a rdfs:Class ;
  rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.02)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001456 , obo:VO_0007748 .

obo:VO_0010374 a rdfs:Class ;
  rdfs:label "Frozen Formulation - Recombinant Human Albumin (RHA) - ProQuad vaccine" ;
  rdfs:subClassOf obo:VO_0000091 , obo:VO_0000484 .

obo:IAO_8000016 a rdfs:Class ;
  rdfs:label "taxonomic bridge ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000004 .

obo:VO_0019898 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0001936 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4479.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002356 .

obo:VO_0002638 a rdfs:Class ;
  rdfs:label "obsolete guaB from Salmonella spp." ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" .

obo:VO_0017118 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017578 .

obo:VO_0017099 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis] Box of 20" ;
  rdfs:subClassOf obo:VO_0017096 , obo:VO_0017118 , obo:VO_0017569 .

obo:VO_0016171 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015889 .

obo:VO_0002389 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0001468 , obo:VO_0002390 .

obo:VO_0003499 a rdfs:Class ;
  rdfs:label "human influenza A (H1N1)-like virus vaccine" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003495 .

obo:VO_0020290 a rdfs:Class ;
  rdfs:label "Vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML [Vaxchora]" ;
  rdfs:subClassOf obo:VO_0003082 , obo:VO_0020289 .

obo:VO_0003054 a rdfs:Class ;
  rdfs:label "intravesical vaccination" ;
  rdfs:comment "The injection of a given substance directly into the bladder via a urethral catheter instead of being injected under the skin." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0003950 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML" ;
  rdfs:subClassOf obo:VO_0003949 .

obo:VO_0010851 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0015811 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 3" ;
  rdfs:subClassOf obo:VO_0015494 .

obo:VO_0000572 a rdfs:Class ;
  rdfs:label "vaccination protocol" ;
  rdfs:comment "vaccination protocol is the protocol of a vaccination procedure." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:VO_0007214 a rdfs:Class ;
  rdfs:label "Ag NY-ESO-1 vaccine" ;
  rdfs:comment "A cancer vaccine made of a recombinant NY-ESO-1 protein with a TLR7 agonist" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0015638 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015572 , obo:VO_0015669 .

obo:VO_0004732 a rdfs:Class ;
  rdfs:label "ALVAC-BTV-CP(VP2/VP5) vaccine" ;
  rdfs:subClassOf obo:VO_0001515 .

obo:OPL_0000271 a rdfs:Class ;
  rdfs:label "Plasmodium erythrocytic merozoite" ;
  rdfs:comment "A Plasmodium merozoite that is produced in an erythrocytic schizont and released into the bloodstream of a vertebrate host. These forms invade erythrocytes." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000270 .

obo:VO_0000614 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae protein P6 with cholera toxin vaccine" ;
  rdfs:subClassOf obo:VO_0000471 .

obo:VO_0010190 a rdfs:Class ;
  rdfs:label "influenza, recombinant, quadrivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0010415 .

obo:VO_0001308 a rdfs:Class ;
  rdfs:label "PMMA vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant made from the emulsion polymerization of methyl methacrylate." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0006029 a rdfs:Class ;
  rdfs:label "meningococcal A polysaccharide vaccine (non-US)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 .

obo:CL_0000113 a rdfs:Class ;
  rdfs:label "mononuclear phagocyte" ;
  rdfs:comment "A vertebrate phagocyte with a single nucleus." ;
  rdfs:subClassOf obo:CL_0000518 , obo:CL_0000842 .

obo:VO_0007749 a rdfs:Class ;
  rdfs:label "licensed duck vaccine" ;
  rdfs:subClassOf obo:VO_0000657 , obo:VO_0001469 , obo:VO_0001528 .

obo:VO_0007326 a rdfs:Class ;
  rdfs:label "anti-HER2/HER3 dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine that uses anti-HER2/HER3 dendritic cells in combination with Pembrolizumab in patients with Asymptomatic Brain Metastasis From Triple Negative Breast Cancer (TNBC) or HER2+ Breast Cancer (HER2+BC). The dendritic cells boost the immune system, and the Pembrolizumab enhances cancer immune responses, in combination they may shrink the cancer." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0015870 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 20" ;
  rdfs:subClassOf obo:VO_0015614 , obo:VO_0015692 , obo:VO_0015994 .

obo:VO_0004114 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae outer membrane recombinant P4 vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012185 .

obo:VO_0004895 a rdfs:Class ;
  rdfs:label "female biological sex datum" ;
  rdfs:comment "A biological sex datum that represents the biological sex of an animal (including human) as being female." ;
  rdfs:subClassOf obo:VO_0001194 .

obo:VO_0010874 a rdfs:Class ;
  rdfs:label "LcrV from y. pestis CO92" ;
  rdfs:comment "MAb BA5 protected animals against plague, neutralized the Y. pestis type III secretion pathway and promoted opsonophagocytic clearance of bacteria in blood. LcrV residues 196-225 were necessary and sufficient for MAb BA5 binding.  These results identify LcrV residues 196-225 as a linear epitope that is recognized by the murine immune system to confer plague protection [PubMed: 20005318]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0020691 a rdfs:Class ;
  rdfs:label "Aconitum napellus extract / ferrous cation / Gelsemium Sempervirens Preparation / Gentiana lutea root extract / Influenza A virus / Lactate / Luffa operculata whole extract / VERATRUM ALBUM Preparation Injectable Solution [Metavirulent]" ;
  rdfs:subClassOf obo:VO_0020690 .

obo:VO_0003756 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003755 .

obo:VO_0001772 a rdfs:Class ;
  rdfs:label "equine influenza killed virus vaccine (USDA: 1505.24)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0001176 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0017477 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017476 .

obo:VO_0016859 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Pur] Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0016807 .

obo:VO_0007138 a rdfs:Class ;
  rdfs:label "Retroviral Vector MFGS-MOv18-gamma Vaccine" ;
  rdfs:comment "A recombinant retrovirus containing the modified murine retroviral vector MFG-S encoding a chimeric construct, MOv18-gamma. MOv18 is a murine monoclonal antibody developed against epitope of human folate binding protein, which is overexpressed on more than 90% of non-mucinous epithelial ovarian neoplasms. The chimeric construct (MOv18-gamma) encodes the variable region of MOv18 antibody, and the gamma chain of human T-cell receptor. This virion might be used to transduce autologous T lymphocytes, and reintroduced back to the patient after expansion ex vivo to invoke specific immune response against ovarian cancer cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0002926 a rdfs:Class ;
  rdfs:label "obsolete SC602" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" .

obo:VO_0017506 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0017684 .

obo:VO_0010454 a rdfs:Class ;
  rdfs:label "licensed human tick-borne encephalitis virus vaccine" ;
  rdfs:comment "Tick-borne Encephalitis Virus (TBEV) vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0012190 .

obo:VO_0010993 a rdfs:Class ;
  rdfs:label "ECSE_P3-0034" ;
  rdfs:comment "Oral immunization of FaeG-expressing L. lactis exhibits a protective response against ETEC infection in mice [PubMed: 19277476]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:DOID_1793 a rdfs:Class ;
  rdfs:label "pancreatic cancer"@en ;
  rdfs:comment "An endocrine gland cancer located_in the pancreas."@en ;
  rdfs:subClassOf obo:DOID_170 , obo:DOID_28 .

obo:VO_0018677 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 Powder for Oral Suspension [Rotarix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018676 .

obo:VO_0002306 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.26)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002480 .

obo:VO_0010331 a rdfs:Class ;
  rdfs:label "intralesional route" ;
  rdfs:comment "A route of administration that inject the material (such as vaccines, allergens) directly into a lesion or into the skin." ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0001571 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001501 .

obo:VO_0007195 a rdfs:Class ;
  rdfs:label "Ad-sig-hMUC-1/ecdCD40L vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant adenoviral vector encoding the tumor-associated antigen (TAA) human MUC-1 (hMUC-1) linked to the extracellular domain (ecd) of the co-stimulatory molecule CD40 ligand (CD40L) and an adenovirus signal sequence that encodes a secretory signal peptide (Ad-sig) with potential immunostimulating and antineoplastic activities. Due to the presence of the secretory signal peptide expressed by Ad-sig in the vaccine construct, transfected cells may secrete a fusion protein composed of hMUC-1 and the CD40L ecd. The CD40L moiety part of the fusion protein binds to CD40 receptors on dendritic cells (DCs). Subsequently, DCs may be activated and migrate, T-cells may expand, and a cytotoxic T lymphocyte (CTL) response against tumor cells that overexpress hMUC-1 may follow. MUC-1 is a hypoglycosylated TAA overexpressed by epithelial cancer cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0005484 , obo:VO_0005486 , obo:VO_0005489 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0018060 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 25" ;
  rdfs:subClassOf obo:VO_0018053 , obo:VO_0018078 , obo:VO_0018148 .

obo:VO_0004201 a rdfs:Class ;
  rdfs:label "J5dLPS/OMP vaccine" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0018467 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0018454 .

obo:VO_0001454 a rdfs:Class ;
  rdfs:label "Human herpesvirus 2 gene" ;
  rdfs:comment "A viral gene that is from Human herpesvirus 2." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0003790 a rdfs:Class ;
  rdfs:label "influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010310 , obo:VO_0010415 .

obo:VO_0020984 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, strain A / Victoria / 361/2011 H3N2 - Derived Strain Used Ivr-165 0.00752 MG/ML" ;
  rdfs:subClassOf obo:VO_0020982 .

obo:VO_0003859 a rdfs:Class ;
  rdfs:label "Imovax Injectable Product" ;
  rdfs:subClassOf obo:VO_0000063 .

obo:VO_0002165 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.19)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0018228 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018251 .

obo:VO_0006080 a rdfs:Class ;
  rdfs:label "Tick-borne encephalitis vaccine inactivated preservative free 0.5mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000712 , obo:VO_0000952 .

obo:VO_0016079 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015869 .

obo:VO_0007518 a rdfs:Class ;
  rdfs:label "obsolete Melanoma DNA vaccine TA2M(TM) encoding tyrosinase peptides" .

obo:NCBITaxon_9989 a rdfs:Class ;
  rdfs:label "Rodentia" ;
  rdfs:subClassOf obo:NCBITaxon_314147 .

obo:VO_0005181 a rdfs:Class ;
  rdfs:label "chimpanzee adenovirus Oxford1 vaccine vector" ;
  rdfs:comment "A chimpanzee adenovirus vaccine vector that  patented by Oxford and derived from ChAd serotype Y25 that exchanges the native E4 orf4, orf6 and orf6/7 genes for those from HAdV-C5" ;
  rdfs:subClassOf obo:VO_0001055 .

obo:VO_0002631 a rdfs:Class ;
  rdfs:label "fliC from Salmonella Enteritidis" ;
  rdfs:comment "A fliC mutant, in combination with a guaB mutant, is attenuated in mice and chickens and induces significant protection from challenge with wild type S. enterica" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001422 .

obo:VO_0003904 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2018-2019 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003903 .

obo:VO_0004382 a rdfs:Class ;
  rdfs:label "Ebola virus recombinant adenovirus vaccine AdC7-ZGP encoding GP" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000726 .

obo:VO_0020163 a rdfs:Class ;
  rdfs:label "pertussis vaccine 0.0468 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010435 .

obo:VO_0001261 a rdfs:Class ;
  rdfs:label "DDA vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is dimethyldioctadecylammonium bromide (DDA), a lipophilic quaternary ammonium salt known as a good adjuvant when co-administered systemically or nasally with an antigen." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0017995 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0017992 , obo:VO_0018036 .

obo:OPL_0000284 a rdfs:Class ;
  rdfs:label "Plasmodium hepatic trophozoite" ;
  rdfs:comment "A Plasmodium trophozoite that is found in hepatocytes." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000281 .

obo:VO_0020786 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 ORGANISMS Injectable Suspension [OncoTICE] by MSD" ;
  rdfs:subClassOf obo:VO_0020783 .

obo:VO_0017496 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:DOID_3620 a rdfs:Class ;
  rdfs:label "central nervous system cancer"@en ;
  rdfs:comment "A nervous system cancer that is located_in the central nervous system."@en ;
  rdfs:subClassOf obo:DOID_3093 , obo:DOID_331 .

obo:VO_0017801 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017799 .

obo:NCBITaxon_10405 a rdfs:Class ;
  rdfs:label "Orthohepadnavirus" ;
  rdfs:subClassOf obo:NCBITaxon_2732514 .

obo:VO_0019275 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020493 .

obo:VO_0020826 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML [HibTITER]" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0001176 , obo:VO_0003455 , obo:VO_0010415 .

obo:VO_0000652 a rdfs:Class ;
  rdfs:label "licensed cat vaccine" ;
  rdfs:subClassOf obo:VO_0000363 , obo:VO_0001465 .

obo:VO_0002524 a rdfs:Class ;
  rdfs:label "ureC from Actinobacillus pleuropneumoniae" ;
  rdfs:comment "Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001384 .

obo:VO_0002227 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002403 , obo:VO_0007748 .

obo:VO_0016193 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Mevita" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:VO_0019106 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0021088 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.006 MG/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0000746 , obo:VO_0001214 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0002870 a rdfs:Class ;
  rdfs:label "Salmonella Gallinarum cbiA/cobS mutant vaccine" ;
  rdfs:comment "A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis" ;
  rdfs:subClassOf obo:VO_0002508 .

obo:IAO_8000001 a rdfs:Class ;
  rdfs:label "base ontology module"@en ;
  rdfs:comment "An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies."@en ;
  rdfs:seeAlso <https://github.com/INCATools/ontology-starter-kit/issues/50> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:VO_0015945 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 250" ;
  rdfs:subClassOf obo:VO_0015638 , obo:VO_0015719 , obo:VO_0016043 .

obo:VO_0003058 a rdfs:Class ;
  rdfs:label "Mycobacterium marinum vaccine" ;
  rdfs:comment "A vaccine that protects against Mycobacterium marinum." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000592 .

obo:VO_0018564 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0018561 , obo:VO_0018719 .

obo:VO_0004035 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis DNA vaccine ESAT-6" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:VO_0018435 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II]" ;
  rdfs:subClassOf obo:VO_0018425 .

obo:VO_0021019 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2000 PFU" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0017884 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0015070 .

obo:VO_0000618 a rdfs:Class ;
  rdfs:label "vaccine antigen role" ;
  rdfs:subClassOf obo:VO_0000617 .

obo:VO_0015940 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 20" ;
  rdfs:subClassOf obo:VO_0015637 , obo:VO_0016037 .

obo:VO_0007202 a rdfs:Class ;
  rdfs:label "Adenovirus 5-Human Guanylyl Cyclase C-PADRE vaccine" ;
  rdfs:comment "A replication-defective, recombinant adenoviral serotype 5 (Ad5) encoding human guanylyl cyclase C (hGCC) and the synthetic Pan DR epitope (PADRE), with potential antineoplastic and immunomodulating activities. Upon intramuscular administration, the Ad5-hGCC-PADRE vaccine expresses hGCC, which may induce both humoral and cellular immune responses against tumor cells expressing the hGCC antigen. This results in the immune-mediated inhibition of tumor cell proliferation, and leads to tumor death. The hGCC protein is normally restricted to intestinal epithelial cells but is overexpressed by metastatic colorectal tumors. PADRE is a helper T-lymphocyte epitope that is able to augment the magnitude and duration of the cytotoxic T-lymphocyte (CTL) response." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005490 , obo:VO_0007657 .

obo:VO_0015891 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [H B Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015621 , obo:VO_0015724 , obo:VO_0016007 .

obo:VO_0018197 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000737 .

obo:VO_0011312 a rdfs:Class ;
  rdfs:label "NS1 from Dengue virus" ;
  rdfs:comment "The protective efficacy and immune responses of mice intramuscularly injected with plasmid encoding DEN-2 non-structural protein 1 (NS1) was evaluated. Intravenously challenged by lethal DEN-2, mice vaccinated with NS1-DNA exhibited a delay onset of paralysis, a marked decrease of morbidity, and a significant enhancement of survival [PubMed: 12922127]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010844 .

obo:VO_0020998 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 PFU [Varivax]" ;
  rdfs:subClassOf obo:VO_0000119 , obo:VO_0020997 .

obo:VO_0002519 a rdfs:Class ;
  rdfs:label "apxIIC from Actinobacillus pleuropneumoniae" ;
  rdfs:comment "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001384 .

obo:VO_0017012 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 2 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0017011 .

obo:VO_0016610 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Twinrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0016561 , obo:VO_0016615 .

obo:VO_0002216 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.28)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002411 , obo:VO_0007748 .

obo:VO_0000320 a rdfs:Class ;
  rdfs:label "pTHamp DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:NCBITaxon_9963 a rdfs:Class ;
  rdfs:label "Caprinae" ;
  rdfs:subClassOf obo:NCBITaxon_9895 .

obo:VO_0020254 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0003340 .

obo:VO_0007236 a rdfs:Class ;
  rdfs:label "Alpha-1,3-galactosyltransferase-expressing Allogeneic Renal Cell Carcinoma Vaccine" ;
  rdfs:comment "An allogeneic renal cell cancer (RCC) vaccine composed of cell line-derived RCCs that are genetically engineered to express the murine alpha-1,3-galactosyltransferase (GalT), with potential immunostimulatory and antineoplastic activities. Not naturally occurring in humans, GalT catalyzes the expression of foreign alpha-1,3-galactosyl (alpha-gal) carbohydrate epitopes on the cell membranes of the allogeneic RCCs present in the vaccine. This induces a hyperacute rejection reaction involving pre-existing human anti-alpha-gal antibodies, which bind to the foreign alpha-gal epitopes expressed by the allogeneic RCCs. This results in complement-mediated cytotoxicity (CMC) and antibody-dependent cell-mediated cytotoxicity (ADCC) towards endogenous RCCs with unmodified carbohydrate epitopes." ;
  rdfs:subClassOf obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0003118 a rdfs:Class ;
  rdfs:label "M-M-R I vaccine" ;
  rdfs:comment "A vaccine used to protect against measles, mumps, and rubella for 12-15 month-old individuals." ;
  rdfs:subClassOf obo:VO_0000641 , obo:VO_0000731 .

obo:VO_0019416 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.0468 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.0468 MG/ML / diphtheria toxoid vaccine, inactivated 13.4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017799 .

obo:NCBITaxon_90371 a rdfs:Class ;
  rdfs:label "Salmonella enterica subsp. enterica serovar Typhimurium" ;
  rdfs:subClassOf obo:NCBITaxon_59201 .

obo:VO_0007433 a rdfs:Class ;
  rdfs:label "LY6K/VEGFR1/VEGFR2 Multipeptide Vaccine" ;
  rdfs:comment "A multipeptide vaccine consisting of peptides derived from lymphocyte antigen 6 complex locus K (LY6K) and type I and II vascular endothelial growth factor receptors (VEGFRs) with potential antineoplastic activity. Upon administration, LY6K/VEGFR1/VEGFR2 multipeptide vaccine may elicit an antitumor cytotoxic T-lymphocyte (CTL) immune response against LY6K-expressing tumor cells and/or VEGFR-expressing vascular endothelial cells involved in tumor angiogenesis. LY6K is a tumor-associated antigen (TAA) that occurs singly in glycosylphosphatidyl-inositol (GPI)-linked cell-surface glycoproteins or as three-fold repeated domain in the urokinase-type plasminogen activator receptor; VEGFRs are cell surface receptors that stimulate endothelial cell proliferation, invasion, angiogenesis, and vasculogenesis upon ligand binding and receptor activation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005496 , obo:VO_0007657 .

obo:VO_0007089 a rdfs:Class ;
  rdfs:label "Oncovax-ID/IL-2 Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a mixture of a murine lymphoma-derived idiotype and interleukin-2 (IL-2) encapsulated in dimyristoylphosphatidylcholine liposomes. The use of a liposomal carrier confers immunogenicity to the naturally non-immunogenic idiotype." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0015545 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Engerix B]" ;
  rdfs:subClassOf obo:VO_0003419 , obo:VO_0010711 .

obo:VO_0001977 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44F9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002361 .

obo:VO_0001132 a rdfs:Class ;
  rdfs:label "assay of CFU reduction in liver" ;
  rdfs:comment "assay of CFU reduction in liver is a CFU reduction assay that is measured using the extracted liver as the tissue for isolation of infected pathogens." ;
  rdfs:subClassOf obo:VO_0000242 .

obo:NCBITaxon_9526 a rdfs:Class ;
  rdfs:label "Catarrhini" ;
  rdfs:subClassOf obo:NCBITaxon_314293 .

obo:VO_0017984 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.5 MG / meningococcal group C polysaccharide 0.5 MG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.5 MG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.5 MG Injectable Solution by Sanofi" ;
  rdfs:subClassOf obo:VO_0017955 .

obo:VO_0005108 a rdfs:Class ;
  rdfs:label "SARS MA-ExoN vaccine" ;
  rdfs:comment "A SARS recombinant vector vaccine that is made  from of the highly attenuated modified vaccinia virus Ankara (MVA) containing the gene encoding full-length SARS-CoV S" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0020016 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 50000000 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 50000000 MG/ML [Flumist 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020350 .

obo:VO_0004330 a rdfs:Class ;
  rdfs:label "Human papillomavirus DNA vaccine pC16-L1 encoding L1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000667 .

obo:VO_0016326 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 3 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015937 .

obo:VO_0020077 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.12 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.12 MG/ML [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0019998 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML [Fluzone Intradermal 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020480 .

obo:NCBITaxon_28211 a rdfs:Class ;
  rdfs:label "Alphaproteobacteria" ;
  rdfs:subClassOf obo:NCBITaxon_1224 .

obo:VO_0011564 a rdfs:Class ;
  rdfs:label "Neospora caninum NcMAG1 protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0001065 .

obo:VO_0016658 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Opti" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0004586 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus DNA vaccine P-JEV" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000665 .

obo:VO_0003043 a rdfs:Class ;
  rdfs:label "Sindbis virus vaccine" ;
  rdfs:comment "A viral vaccine against infection of an Sindbis virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0003767 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 , obo:VO_0010433 .

obo:VO_0016285 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0016026 .

obo:VO_0017088 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax]" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017563 .

obo:VO_0003440 a rdfs:Class ;
  rdfs:label "Fluzone Intradermal Trivalent vaccine" ;
  rdfs:comment "A trivalent influenza vaccine containing two strains of influenza A and one strain of influenza B for use in people 18 years to 64 years for use during the 2012-2013 season." ;
  rdfs:subClassOf obo:VO_0001176 , obo:VO_0001236 .

obo:VO_0019337 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0003441 , obo:VO_0010444 , obo:VO_0010445 .

obo:VO_0000219 a rdfs:Class ;
  rdfs:label "vaccine solvent" ;
  rdfs:comment "a vaccine component that is used to dissolve vaccine powder into liquid. The vaccine in a powder form has to be reconstituted by mixing vaccine powder with vaccine solvent before administered." ;
  rdfs:subClassOf obo:VO_0000179 .

obo:VO_0019670 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0001768 a rdfs:Class ;
  rdfs:label "Equine Arteritis Modified Live Virus Vaccine (USDA: 1531.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001500 , obo:VO_0007748 .

obo:VO_0003451 a rdfs:Class ;
  rdfs:label "Twinrix Injectable Product" ;
  rdfs:subClassOf obo:VO_0000113 .

obo:VO_0016257 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015919 .

obo:VO_0017107 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017102 .

obo:VO_0016336 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0018524 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Injectable Product" ;
  rdfs:subClassOf obo:VO_0003212 .

obo:VO_0007057 a rdfs:Class ;
  rdfs:label "WT1 126-134 peptide vaccine" ;
  rdfs:comment "A synthetic peptide vaccine consisting of the amino acids 126 through 134 of the human Wilms' Tumor protein-1 (WT1) with potential antitumor activity. WT1, a tumor associated antigen, is overexpressed in most types of leukemia and in a variety of solid cancers. Vaccination with WT1 126-134 peptide vaccine may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005429 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0000991 a rdfs:Class ;
  rdfs:label "pDONR221 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pDONR221. The plasmid length is 4762." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0011085 a rdfs:Class ;
  rdfs:label "Gc" ;
  rdfs:comment "Seoul virus (SEOV) is one of the four known hantaviruses causing hemorrhagic fever with renal syndrome (HFRS).  A replication-competent recombinant canine adenovirus type 2 expressing the Gc protein of SEOV (rCAV-2-Gc) in BALB/c mice induced complete protection against a intensive infectious challenge with ~1,000 50% infective doses (ID50) for SEOV strain CC-2 [PubMed: 20181748]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010768 .

obo:VO_0001950 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1185.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0002358 .

obo:VO_0003488 a rdfs:Class ;
  rdfs:label "influenza B virus B/Phuket/3073/2013 antigen" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:VO_0019281 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0002709 a rdfs:Class ;
  rdfs:label "ORF-A from Feline immunodeficiency virus" ;
  rdfs:comment "Feline immunodeficiency virus (FIV) made defective in the accessory gene ORF-A were previously shown to be greatly attenuated in its ability to replicate in lymphocytes but to grow normally or near normally in other cell types. 3/9 vaccinees (cats) showed no evidence of the challenge virus over a 15-month observation period. In the other vaccinees, the challenge virus was predominant for various periods of time, but pre-existing viral loads and CD4 lymphocyte counts were either unaffected or altered only marginally and transiently" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001433 .

obo:DOID_8736 a rdfs:Class ;
  rdfs:label "smallpox"@en ;
  rdfs:comment "A viral infectious disease that results in infection located in skin, has_material_basis_in Variola virus (Orthopoxvirus variola), which is transmitted by droplets from oral, nasal or pharyngeal mucosa, transmitted by contact with the body fluids, or transmitted by fomites. The infection results in formation of lesions, first on the face, hands and forearms and later on the trunk."@en ;
  rdfs:subClassOf obo:DOID_7 , obo:DOID_934 .

obo:VO_0017332 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000738 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0010415 .

obo:NCBITaxon_548681 a rdfs:Class ;
  rdfs:label "Herpesvirales" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:VO_0010840 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0019644 a rdfs:Class ;
  rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010427 .

obo:VO_0007083 a rdfs:Class ;
  rdfs:label "Racotumomab Vaccine" ;
  rdfs:comment "An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional structure of N-glycolyl ceramides of mono-sialyl lactose, the antigenic target of P3. As a result, this anti-idiotype antibody may stimulate the host immune system to elicit humoral and cellular immune responses against tumor cells expressing NeuGc-GM3 gangliosides, which are expressed in a wide variety of tumor cells." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0018456 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 20" ;
  rdfs:subClassOf obo:VO_0018432 , obo:VO_0018440 .

obo:NCBITaxon_11241 a rdfs:Class ;
  rdfs:label "Rinderpest morbillivirus" ;
  rdfs:subClassOf obo:NCBITaxon_11229 .

obo:VO_0016570 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Hepatitis B Surface Antigen Vaccine Injectable Solution [Ambirix]" ;
  rdfs:subClassOf obo:VO_0016579 .

obo:PR_P0DTC2 a rdfs:Class ;
  rdfs:label "spike glycoprotein (SARS-CoV-2)" ;
  rdfs:comment "A protein that is a translation product of the S gene in SARS-CoV-2." ;
  rdfs:subClassOf obo:PR_000000001 .

obo:VO_0015621 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [H B Vax]" ;
  rdfs:subClassOf obo:VO_0015574 , obo:VO_0015661 .

obo:VO_0020463 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10 by Sanofi" .

obo:VO_0015902 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015624 , obo:VO_0016017 .

obo:VO_0020611 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension by Sanofi" ;
  rdfs:subClassOf obo:VO_0020538 .

obo:VO_0003350 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003351 .

obo:VO_0017466 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 1.5 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017464 .

obo:VO_0007063 a rdfs:Class ;
  rdfs:label "Recombinant Human Papillomavirus Nonavalent Vaccine" ;
  rdfs:comment "A non-infectious, recombinant, nonavalent vaccine prepared from highly purified virus-like particles (VLPs) comprised of the major capsid (L1) proteins from human papillomavirus (HPV) types 6, 11, 16, 18, 31, 33, 45, 52, and 58, with active immunizing activity. Upon administration, the recombinant HPV nonavalent vaccine activates the immune system to produce antibodies against the 9 HPV types. This protects against HPV infection and HPV-related cancers. Altogether, HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58 account for the majority of the HPV types that cause cervical, vulvar, vaginal and anal cancers.‚Äö√†√∂‚àö¬ß" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005488 , obo:VO_0007657 .

obo:VO_0002074 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 12J5.62)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002367 , obo:VO_0007748 .

obo:VO_0010738 a rdfs:Class ;
  rdfs:label "Rotarix vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000658 , obo:VO_0000714 , obo:VO_0001220 , obo:VO_0010449 .

obo:VO_0011093 a rdfs:Class ;
  rdfs:label "Hepatitis B surface antigen" ;
  rdfs:comment "Study compared a current HBV vaccine that contains recombinant hepatitis B surface antigen HBsAg) adsorbed to alum in chimpanzees, with two novel vaccine strategies that have proven superior to the current vaccine in mice. All animals receiving either control or CpG-containing subunit vaccines at 0 and 4 weeks attained titers of HBsAg-specific antibody (anti-HBs) considered protective (> or =10 mIU/ml) and were indeed protected from challenge at 8 weeks with 10(3.5) 50% chimp infectious doses (CID(50)) of intravenous HBV [PubMed: 16428890]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010781 .

obo:VO_0010713 a rdfs:Class ;
  rdfs:label "Epaxal vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000646 , obo:VO_0000714 , obo:VO_0010438 .

obo:VO_0010295 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0018336 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018323 .

obo:VO_0020577 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Influsplit] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020576 .

obo:VO_0015580 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Fendrix]" ;
  rdfs:subClassOf obo:VO_0015532 , obo:VO_0015597 .

obo:VO_0000255 a rdfs:Class ;
  rdfs:label "usage of bronchodilator" ;
  rdfs:subClassOf obo:VO_0000207 .

obo:VO_0019264 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010431 .

obo:VO_0004318 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 recombinant vector vaccine rLaSota/gDFL encoding gD" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000987 .

obo:VO_0005427 a rdfs:Class ;
  rdfs:label "lymphoma vaccine" ;
  rdfs:comment "A cancer vaccine that is used against lymphoma." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0017910 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injectable Solution [Begrivac]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017818 .

obo:VO_0017499 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 2" ;
  rdfs:subClassOf obo:VO_0017676 .

obo:VO_0000597 a rdfs:Class ;
  rdfs:label "obsolete class" .

obo:VO_0000656 a rdfs:Class ;
  rdfs:label "Mumps virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Mumps virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0004613 a rdfs:Class ;
  rdfs:label "smallpox vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0018217 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT / Varicella Virus Vaccine Live (Oka-Merck) strain 1000 UNT Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018248 .

obo:VO_0002964 a rdfs:Class ;
  rdfs:label "Feline infectious peritonitis virus 7ab mutant vaccine" ;
  rdfs:comment "A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens" ;
  rdfs:subClassOf obo:VO_0001504 .

obo:VO_0000116 a rdfs:Class ;
  rdfs:label "pCBINT DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0020183 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 667000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0004815 .

obo:VO_0007463 a rdfs:Class ;
  rdfs:label "HLA-A*2402-Restricted VEGFR1 peptide vaccine" ;
  rdfs:comment "A peptide vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. gp100:280-288(288V) peptide has a valine substitution at amino acid position 288 to improve immunogenicity. Vaccination with gp100:280-288(288V) peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005486 , obo:VO_0005489 , obo:VO_0005490 , obo:VO_0007657 .

obo:VO_0002915 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium znuABC mutant vaccine" ;
  rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0003644 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003639 .

obo:VO_0019464 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 5 MG/ML / tetanus toxoid vaccine, inactivated 10 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0011485 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni FspA1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012182 .

obo:VO_0005375 a rdfs:Class ;
  rdfs:label "T-vant vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuant that is derived from Salmonella enterica serovar typhimurium and is able to induce Th1/Th2/Th17 immune responses through the mechanism of action of TLR4, inflammasome, and DC activation." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0005377 a rdf:Property ;
  rdfs:label "has molecular receptor" ;
  rdfs:comment "An object property that represents a relation between a material entity and a molecular entitiy that serves as the molecular receptor to the material entity." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0003609 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2013-2014 Formula Influenza Virus Vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003607 .

obo:CHEBI_17833 a rdfs:Class ;
  rdfs:label "gentamycin" ;
  rdfs:comment "Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0012381 a rdfs:Class ;
  rdfs:label "LSA-3" ;
  rdfs:comment "In chimpanzees (Pan troglodytes), the primates most closely related to humans and that share a similar susceptibility to P. falciparum liver-stage infection, immunization with LSA-3 induced protection against successive heterologous challenges with large numbers of P. falciparum sporozoites [PubMed: 11062538]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0011445 a rdfs:Class ;
  rdfs:label "E. coli IutA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0012212 a rdfs:Class ;
  rdfs:label "cancer vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a Cancer vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0003500 a rdfs:Class ;
  rdfs:label "human influenza A (H3N2)-like virus vaccine" ;
  rdfs:subClassOf obo:VO_0003495 .

obo:VO_0002241 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47C5.20)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002398 , obo:VO_0007748 .

obo:VO_0002624 a rdfs:Class ;
  rdfs:label "obsolete clpP from Salmonella spp." ;
  rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" .

obo:VO_0018612 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000665 , obo:VO_0010440 .

obo:VO_0017510 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 100" ;
  rdfs:subClassOf obo:VO_0017507 , obo:VO_0017515 .

obo:VO_0016885 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 10 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0016878 .

obo:VO_0000550 a rdfs:Class ;
  rdfs:label "therapeutic vaccine" ;
  rdfs:comment "A vaccine that is used for treatment for a disease." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0018429 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML Injectable Solution [Pneumovax 23]" ;
  rdfs:subClassOf obo:VO_0018419 .

obo:VO_0010988 a rdfs:Class ;
  rdfs:label "IroN from Escherichia coli" ;
  rdfs:comment "Active immunization of BALB/c mice with IroN antigen in Freund's adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed:  17145948 ]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0017026 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension [T-Immun Immuno]" ;
  rdfs:subClassOf obo:VO_0017025 , obo:VO_0017503 .

obo:VO_0001660 a rdfs:Class ;
  rdfs:label "Chicken Anemia Virus Live Virus Vaccine (USDA: 10A1.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001510 , obo:VO_0007748 .

obo:VO_0016946 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension by Lederle Products" ;
  rdfs:subClassOf obo:VO_0016944 .

obo:VO_0020590 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] Box of 20" ;
  rdfs:subClassOf obo:VO_0020587 , obo:VO_0020606 , obo:VO_0020878 .

obo:VO_0016142 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0004684 a rdfs:Class ;
  rdfs:label "rAPMV3-F newcastle disease vaccine" ;
  rdfs:subClassOf obo:VO_0001222 .

obo:VO_0000384 a rdfs:Class ;
  rdfs:label "IL-15 plasmid vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0001342 .

obo:VO_0010209 a rdfs:Class ;
  rdfs:label "Oral Polio Vaccine, Unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 .

obo:VO_0019753 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:NCBITaxon_694009 a rdfs:Class ;
  rdfs:label "Severe acute respiratory syndrome-related coronavirus" ;
  rdfs:subClassOf obo:NCBITaxon_694002 .

obo:VO_0000427 a rdfs:Class ;
  rdfs:label "phase 1 vaccine trial" ;
  rdfs:comment "A vaccine clinical trial that investigates the safety profile of a vaccine in a small group (10-50) of healthy volunteers." ;
  rdfs:subClassOf obo:VO_0000596 .

obo:NCBITaxon_5794 a rdfs:Class ;
  rdfs:label "Apicomplexa" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:VO_0011407 a rdfs:Class ;
  rdfs:label "NIpah Virus G and F Proteins subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012169 .

obo:VO_0002613 a rdfs:Class ;
  rdfs:label "aroA from Salmonella Typhi" ;
  rdfs:comment "An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. typhi Ty2" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001419 .

obo:VO_0003308 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 58 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003299 , obo:VO_0010446 .

obo:NCBITaxon_10995 a rdfs:Class ;
  rdfs:label "Infectious bursal disease virus" ;
  rdfs:subClassOf obo:NCBITaxon_10993 .

obo:VO_0018623 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018620 .

obo:VO_0020768 a rdfs:Class ;
  rdfs:label "BCG, live, Tice strain 12.5 MG Injection" ;
  rdfs:subClassOf obo:VO_0019412 , obo:VO_0020758 .

obo:VO_0020142 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine Prefilled Syringe [Menactra]" ;
  rdfs:subClassOf obo:VO_0000071 , obo:VO_0000561 , obo:VO_0010445 .

obo:VO_0007298 a rdfs:Class ;
  rdfs:label "Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858" ;
  rdfs:comment "A recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0020784 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 ORGANISMS Injectable Suspension [OncoTICE] Box of 1" ;
  rdfs:subClassOf obo:VO_0020783 , obo:VO_0020787 .

obo:VO_0021035 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix]" ;
  rdfs:subClassOf obo:VO_0021033 , obo:VO_0021034 , obo:VO_0021041 .

obo:VO_0019239 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0018755 a rdfs:Class ;
  rdfs:label "Tick-borne encephalitis virus inactivated Injectable Suspension [Fsme Immun]" ;
  rdfs:subClassOf obo:VO_0018754 .

obo:IAO_8000012 a rdfs:Class ;
  rdfs:label "species subset ontology module"@en ;
  rdfs:comment "A subset ontology that is crafted to either include or exclude a taxonomic grouping of species."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:VO_0004876 a rdfs:Class ;
  rdfs:label "Adenovirus Type 4 Vaccine Live 32000 UNT" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003175 .

obo:VO_0010352 a rdfs:Class ;
  rdfs:label "MRESVIA vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000753 .

obo:VO_0002295 a rdfs:Class ;
  rdfs:label "Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4989.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002459 .

obo:VO_0004537 a rdfs:Class ;
  rdfs:label "Pasteurella multocida DNA vaccine pcDNA-OMPH/OMPA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000620 .

obo:VO_0016907 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.016 MG/ML / Bordetella pertussis 0.1 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017288 .

obo:VO_0015091 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015089 .

obo:VO_0015845 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 .

obo:VO_0016868 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 5 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016823 .

obo:VO_0017246 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0017799 .

obo:VO_0007659 a rdfs:Class ;
  rdfs:label "whole tumor cell cancer vaccine" ;
  rdfs:comment "A whole cell cancer vaccine that uses whole tumor cells to deliver cancer antigen(s)." ;
  rdfs:subClassOf obo:VO_0007658 .

obo:VO_0001576 a rdfs:Class ;
  rdfs:label "Brucella Abortus Strain 19, Live Culture, Reduced Dose Vaccine (USDA: 1251.02)" ;
  rdfs:subClassOf obo:VO_0000022 , obo:VO_0000813 .

obo:VO_0018144 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix]" ;
  rdfs:subClassOf obo:VO_0018141 , obo:VO_0018143 , obo:VO_0018181 .

obo:VO_0010471 a rdfs:Class ;
  rdfs:label "absolute correlate of immune protection" ;
  rdfs:subClassOf obo:VO_0010468 .

obo:VO_0017695 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Pediacel] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017690 .

obo:VO_0000319 a rdfs:Class ;
  rdfs:label "pTH DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003837 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 3 (Saukett)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003834 .

obo:VO_0020800 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 UNT [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020799 .

obo:VO_0010099 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA7" ;
  rdfs:comment "A GRA7 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0011351 a rdfs:Class ;
  rdfs:label "Leishmania infantum HASPB2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012159 .

obo:VO_0017043 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 50 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0017042 .

obo:VO_0010284 a rdfs:Class ;
  rdfs:label "vaccine preservative datum" ;
  rdfs:comment "A measurment datum that records the vaccine preservative of a vaccine." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0011549 a rdfs:Class ;
  rdfs:label "Plasmodium berghei CS protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0002513 .

obo:VO_0011171 a rdfs:Class ;
  rdfs:label "HN" ;
  rdfs:comment "A novel mumps vaccine with good immunity and safety was developed by selecting an antigen (HN) component of the mumps virus. The clinical and pathological observations after challenge of vaccinated rhesus monkeys indicated further that the immune response induced by this vaccine provided complete protection from wild-type virus infection [PubMed: 18597904]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010785 .

obo:VO_0020393 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typherix]" ;
  rdfs:subClassOf obo:VO_0020360 , obo:VO_0020472 .

obo:VO_0001547 a rdfs:Class ;
  rdfs:label "Feline Leukemia Killed Virus Vaccine (USDA: 1555.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0000843 , obo:VO_0007748 .

obo:VO_0015229 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0015339 .

obo:VO_0015661 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015492 .

obo:VO_0001103 a rdfs:Class ;
  rdfs:label "inactivation" ;
  rdfs:comment "Inactivation is a processual entity that produces inactive material." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0003086 a rdfs:Class ;
  rdfs:label "obsolete RB51 induced immune protection" .

obo:VO_0002587 a rdfs:Class ;
  rdfs:label "carB from Escherichia coli" ;
  rdfs:comment "A carAB mutant is attenuated in turkeys and induces significant protection from challenge with wild type E. coli" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000161 .

obo:VO_0004546 a rdfs:Class ;
  rdfs:label "Brucella abortus DNA vaccine pVF278" ;
  rdfs:subClassOf obo:VO_0001225 .

obo:VO_0018770 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0001870 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Rabies Modified Live & Killed Virus Vaccine (USDA: 16T9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0002439 , obo:VO_0007748 .

obo:VO_0016463 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0002605 a rdfs:Class ;
  rdfs:label "wbtI from Francisella tularensis" ;
  rdfs:comment "A wbtI mutant is attenuated in mice. The mutant protected against a low dose challenge with the parental strain, but was less effective against higher doses. However, increasing the immunization dose increased the resistance to higher challenge doses" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0016038 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 3" ;
  rdfs:subClassOf obo:VO_0003422 .

obo:NCBITaxon_151340 a rdfs:Class ;
  rdfs:label "Papillomaviridae" ;
  rdfs:subClassOf obo:NCBITaxon_2732421 .

obo:VO_0002069 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 12H1.4M)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002367 , obo:VO_0007748 .

obo:VO_0020103 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003950 , obo:VO_0018801 .

obo:VO_0018504 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0018502 .

obo:VO_0004458 a rdfs:Class ;
  rdfs:label "Chinese Schistosoma japonicum DNA vaccine SjCTPI" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001229 .

obo:BFO_0000020 a rdfs:Class ;
  rdfs:label "specifically dependent continuant"@en ;
  rdfs:comment "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:VO_0005119 a rdfs:Class ;
  rdfs:label "MERS England1 S DNA + England1 S protein subunit vaccine" ;
  rdfs:comment "A MERS combination vaccine made of made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein and a DNA vaccine that is a plasmid  that encoded S1 subunit" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000534 , obo:VO_0004900 .

obo:VO_0004827 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 1100000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0004825 .

obo:NCBITaxon_2109 a rdfs:Class ;
  rdfs:label "Mycoplasmopsis synoviae" ;
  rdfs:subClassOf obo:NCBITaxon_2895623 .

obo:VO_0017387 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Dt Rix]" ;
  rdfs:subClassOf obo:VO_0018788 .

obo:VO_0019829 a rdfs:Class ;
  rdfs:label "influenza A virus A/Norway/16606/2021 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Victoria/1/2020 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Austria/1359417/2021 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0000805 a rdfs:Class ;
  rdfs:label "effective" ;
  rdfs:subClassOf obo:VO_0000804 .

obo:OPL_0000416 a rdfs:Class ;
  rdfs:label "Plasmodium chabaudi lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Plasmodium chabaudi." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0010727 a rdfs:Class ;
  rdfs:label "obsolete Menomune A/C/Y/W-135 vaccine" ;
  rdfs:comment "Trade Name: Menomune A/C/Y/W-135" .

obo:VO_0004690 a rdfs:Class ;
  rdfs:label "YF17D- HIV-1 p24 vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0015332 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated 320 UNT/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution [Vivaxim]" ;
  rdfs:subClassOf obo:VO_0015326 , obo:VO_0015330 , obo:VO_0015331 .

obo:VO_0007648 a rdfs:Class ;
  rdfs:label "OVA-TEXO vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:DOID_14456 a rdfs:Class ;
  rdfs:label "Brucella melitensis brucellosis"@en ;
  rdfs:comment "A brucellosis that involves an infection caused by Brucella melitensis [NCBITaxon:29459] in cattle, goats, sheep and humans. The disease has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom limb pain and has_symptom back pain."@en ;
  rdfs:subClassOf obo:DOID_11077 .

obo:VO_0003324 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 19F vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003224 .

obo:VO_0000749 a rdfs:Class ;
  rdfs:label "Parainfluenza virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Parainfluenza virus." ;
  rdfs:subClassOf obo:VO_0000609 .

obo:VO_0011272 a rdfs:Class ;
  rdfs:label "TcpF" ;
  rdfs:comment "Antibodies generated against TcpF are protective against experimental V. cholerae infection in the infant mouse cholera model [PubMed: 16040956]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010848 .

obo:VO_0018206 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 TCID / Mumps virus 12500 TCID / Rubella virus 1000 TCID [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0000069 , obo:VO_0018245 .

obo:VO_0016431 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:NCBITaxon_28174 a rdfs:Class ;
  rdfs:label "Vibrio ordalii" ;
  rdfs:subClassOf obo:NCBITaxon_641 .

obo:VO_0015962 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015730 , obo:VO_0015736 , obo:VO_0016046 .

obo:VO_0002813 a rdfs:Class ;
  rdfs:label "obsolete non-infectious disease vaccine" ;
  rdfs:comment "A vaccine that prevents or treats a non-infectious disease." .

obo:VO_0017162 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Pediacel] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017157 .

obo:VO_0004402 a rdfs:Class ;
  rdfs:label "EAU DNA vaccine IRBP-DNA encoding IRBP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002837 .

obo:VO_0019253 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017381 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0004710 a rdfs:Class ;
  rdfs:label "rOka-gD2- HSV-2 vaccine" ;
  rdfs:subClassOf obo:VO_0012168 .

obo:VO_0001911 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002345 .

obo:VO_0020846 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0015739 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 250" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015804 .

obo:VO_0003443 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide vaccine" ;
  rdfs:subClassOf obo:VO_0000671 , obo:VO_0001255 .

obo:VO_0003505 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0003504 .

obo:VO_0017576 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017555 .

obo:VO_0015838 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] by Sanofi" ;
  rdfs:subClassOf obo:VO_0015632 .

obo:VO_0021127 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2021 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020492 .

obo:VO_0004062 a rdfs:Class ;
  rdfs:label "Helicobacter pylori GltA Protein vaccine" ;
  rdfs:subClassOf obo:VO_0012181 .

obo:OPL_0000312 a rdfs:Class ;
  rdfs:label "Vertebrate hepatocyte" ;
  rdfs:comment "A hepatocyte that is a part of or originated from a vertebrate." ;
  rdfs:subClassOf obo:CL_0000182 .

obo:VO_0003477 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0007377 a rdfs:Class ;
  rdfs:label "DNA plasmid-encoding Interleukin-12/HPV DNA plasmids therapeutic vaccine INO-3112" ;
  rdfs:comment "A DNA-based combination immunotherapeutic, INO-3112, composed of VGX-3100, a preparation of DNA plasmids encoding the E6 and E7 genes of human papillomavirus (HPV) subtypes 16 and 18, combined with INO-9012, a DNA plasmid encoding the immune activator and pro-inflammatory cytokine human interleukin-12 (IL-12) with potential immunoactivating and antineoplastic activities. Upon intramuscular delivery by electroporation of VGX-3100, the HPV E6 and E7 proteins are translated in cells and elicit a cytotoxic T-lymphocyte (CTL) response against cancer cells expressing the E6 and E7 antigens, resulting in tumor cell lysis. HPV type 16 and HPV type 18 are associated with the development of certain types of cancer. Upon intramuscular delivery by electroporation of INO-9012, IL-12 is expressed and activates the immune system by promoting the activation of natural killer cells (NK cells), inducing secretion of interferon-gamma (IFN-g) and promoting CTL responses against tumor cells. This boosts the immune response and results in increased CTL-mediated tumor cell death as compared with the administration of VGX-3100 alone." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007660 .

obo:CHEBI_64220 a rdfs:Class ;
  rdfs:label "monosodium glutamate" ;
  rdfs:comment "An organic sodium salt that is the monosodium salt of glutamic acid." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0000645 a rdfs:Class ;
  rdfs:label "licensed fish vaccine" ;
  rdfs:subClassOf obo:VO_0000363 , obo:VO_0001462 .

obo:VO_0001046 a rdfs:Class ;
  rdfs:label "Herpes simplex virus vaccine vector" ;
  rdfs:comment "a herpesvirus vaccine vector that uses a herpes simplex virus strain" ;
  rdfs:subClassOf obo:VO_0000283 .

obo:VO_0002259 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4847.23)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000542 , obo:VO_0000640 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0007748 .

obo:VO_0005512 a rdfs:Class ;
  rdfs:label "ME-F-1051 (VesiVax®) vaccine adjuvant" ;
  rdfs:comment "Vaccine adjuvant based on VesiVax® liposome." ;
  rdfs:subClassOf obo:VO_0000366 .

obo:VO_0001425 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica gene" ;
  rdfs:comment "A bacterial gene that is from Yersinia enterocolitica." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0003655 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2018-2019 Vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003650 .

obo:VO_0018263 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injectable Solution [Verorab]" ;
  rdfs:subClassOf obo:VO_0018270 .

obo:VO_0020128 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017821 .

obo:VO_0020314 a rdfs:Class ;
  rdfs:label "Fluarix 2010-2011 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000045 , obo:VO_0000578 , obo:VO_0010426 .

obo:VO_0001743 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine (USDA: 14P5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000932 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0004467 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine sB encoding E" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0007392 a rdfs:Class ;
  rdfs:label "EGFRvIII Peptide Vaccine" ;
  rdfs:comment "An antineoplastic vaccine directed against a peptide found in the epidermal growth factor receptor class III variant (EGFRvIII), a constitutively activated mutant of the wild-type tyrosine kinase. This protein variant is present in a substantial proportion of malignant gliomas and other human cancers." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0017835 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Prefilled Syringe [Invivac]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017888 .

obo:VO_0011066 a rdfs:Class ;
  rdfs:label "3-1E" ;
  rdfs:comment "The Eimeria tenella antigen gene (3-1E) and chicken interferon gamma gene (ChIFN-gamma) were subcloned into the mammalian expression vector proVAX forming the plasmids proE and prol.  After challenge the proIE-vaccinated chickens showed protective immunity as demonstrated by significantly reduced oocyst shedding [PubMed: 17274297]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010823 .

obo:VO_0010432 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2016-2017" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0007094 a rdfs:Class ;
  rdfs:label "NY-ESO-1(157-165) peptide-pulsed autologous dendritic cell vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with a peptide derived from the tumor associated antigen human cancer-testis antigen NY-ESO-1 (NY-ESO-1(157-165)), with potential immunostimulatory and antineoplastic activities. Upon administration, the NY-ESO-1(157-165) peptide-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount both an anti-tumoral cytotoxic T-lymphocyte (CTL) and an antibody-mediated immune response against NY-ESO-1-expressing tumor cells, which may result in tumor cell lysis. NY-ESO-1 is expressed both in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0001165 a rdfs:Class ;
  rdfs:label "intraperitoneal pathogen challenge" ;
  rdfs:comment "intraperitoneal pathogen challenge is a pathogen challenge process that occurs in the intraperitoneal site of a host." ;
  rdfs:subClassOf obo:OBI_0000712 .

obo:VO_0020917 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020913 .

obo:VO_0017750 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] Box of 5" ;
  rdfs:subClassOf obo:VO_0017747 , obo:VO_0017753 .

obo:VO_0001750 a rdfs:Class ;
  rdfs:label "Giardia Lamblia Killed Protozoa Vaccine (USDA: 18G5.00)" ;
  rdfs:subClassOf obo:VO_0000315 , obo:VO_0000455 , obo:VO_0001083 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0003201 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0003196 .

obo:VO_0010914 a rdfs:Class ;
  rdfs:label "P4 from Haemophilus influenzae" ;
  rdfs:comment "The P4 protein is an integral outer membrane protein that has a role in acquiring hemin and nucleosides [PubMed: 1715322 ]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:VO_0010363 a rdfs:Class ;
  rdfs:label "Varivax (Frozen) vaccine" ;
  rdfs:subClassOf obo:VO_0000119 .

obo:VO_0019887 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Solution [Flublok 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0003878 , obo:VO_0019886 .

obo:VO_0016759 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016693 .

obo:VO_0001830 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.26)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0002477 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0016893 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adacel]" ;
  rdfs:subClassOf obo:VO_0016892 , obo:VO_0017265 .

obo:VO_0015917 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [Hevac B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015630 , obo:VO_0015682 , obo:VO_0016025 .

obo:VO_0015800 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015493 .

obo:VO_0003953 a rdfs:Class ;
  rdfs:label "Ixiaro (Japanese Encephalitis Vaccine, Inactivated, Adsorbed) Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003951 , obo:VO_0018618 .

obo:VO_0020076 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.12 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.12 MG/ML [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020478 .

obo:VO_0002837 a rdfs:Class ;
  rdfs:label "autoimmune disease vaccine" ;
  rdfs:comment "A vaccine that prevents or treats an autoimmune disease." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005503 .

obo:VO_0016874 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Pediacel] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016814 .

obo:VO_0017876 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.05 MG" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:OPL_0000349 a rdfs:Class ;
  rdfs:label "Plasmodium vivax merozoite stage" ;
  rdfs:comment "A merozoite stage in the Plasmodium vivax life cycle." ;
  rdfs:subClassOf obo:OPL_0000036 , obo:OPL_0000292 , obo:OPL_0000374 .

obo:VO_0002943 a rdfs:Class ;
  rdfs:label "Yersinia pestis pcm mutant vaccine" ;
  rdfs:comment "A pcm mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:DOID_11405 a rdfs:Class ;
  rdfs:label "diphtheria"@en ;
  rdfs:comment "A primary bacterial infectious disease that is characterized by sore throat, low fever, and an adherent membrane (a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. A milder form of diphtheria can be restricted to the skin. It is caused by Corynebacterium diphtheriae, an aerobic Gram-positive bacterium. Diphtheria toxin spreads through the bloodstream and can lead to potentially life-threatening complications that affect other organs of the body, such as the heart and kidneys."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:VO_0015672 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015598 .

obo:VO_0001396 a rdfs:Class ;
  rdfs:label "cocktail vaccine containing subunit vaccine and inactivated whole organism vaccine" ;
  rdfs:comment "a cocktail vaccine that contains both subunit vaccine and inactivated whole organism vaccines." ;
  rdfs:subClassOf obo:VO_0000315 , obo:VO_0000534 , obo:VO_0001395 .

obo:VO_0011153 a rdfs:Class ;
  rdfs:label "A2" ;
  rdfs:comment "Study results show that a single intraperitoneal administration of the A2-recombinant L. tarentolae strain expressing the Leishmania donovani A2 antigen protects BALB/c mice against L. infantum challenge and that protective immunity is associated with high levels of IFN-gamma production prior and after challenge [PubMed: 19818721]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0000110 a rdfs:Class ;
  rdfs:label "E. coli O157:H7 intimin vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0015883 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 25" ;
  rdfs:subClassOf obo:VO_0015618 , obo:VO_0016005 .

obo:VO_0004922 a rdfs:Class ;
  rdfs:label "child age" ;
  rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ;
  rdfs:subClassOf obo:VO_0004921 .

obo:OPL_0000140 a rdfs:Class ;
  rdfs:label "erythrocytic ring trophozoite stage" ;
  rdfs:comment "An early trophozoite stage of Plasmodium sp. where a large central vacuole and peripheral nucleus give an appearance of a signet ring." ;
  rdfs:subClassOf obo:OPL_0000243 .

obo:NCBITaxon_11673 a rdfs:Class ;
  rdfs:label "Feline immunodeficiency virus" ;
  rdfs:subClassOf obo:NCBITaxon_11646 .

obo:VO_0005199 a rdfs:Class ;
  rdfs:label "COVID-19 recombinant vector vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0004908 .

obo:VO_0010443 a rdfs:Class ;
  rdfs:label "licensed human mycobacterium tuberculosis vaccine" ;
  rdfs:comment "Mycobacterium tuberculosis vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000077 , obo:VO_0000635 .

obo:VO_0019484 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.015 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003409 , obo:VO_0020836 .

obo:VO_0020195 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA spike protein Injectable Suspension [Comirnaty]" ;
  rdfs:subClassOf obo:VO_0004987 , obo:VO_0020194 .

obo:VO_0017037 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 10 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0017036 .

obo:VO_0020251 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.008 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML Prefilled Syringe [Prevnar]" ;
  rdfs:subClassOf obo:VO_0000090 , obo:VO_0010210 , obo:VO_0010445 .

obo:VO_0016073 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015868 .

obo:VO_0002910 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Gallinarum relA/spoT mutant vaccine" ;
  rdfs:comment "A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum" .

obo:VO_0019768 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hawaii/70/2019 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Minnesota/41/2019 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML [Flublok Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020325 .

obo:VO_0003729 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML [Afluria 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003727 .

obo:VO_0005364 a rdfs:Class ;
  rdfs:label "Tomatine vaccine adjuvant" ;
  rdfs:comment "A carbohydrate vaccine adjuvant that is tomatidine in which the hydroxy group at position 3 is linked to lycotetraose, a tetrasaccharide composed of two units of D-glucose, one unit of D-xylose, and one unit of D-galactose." ;
  rdfs:subClassOf obo:VO_0001359 .

obo:VO_0002367 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Vaccine" ;
  rdfs:subClassOf obo:VO_0001502 , obo:VO_0002365 .

obo:VO_0016655 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Mevita" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:NCBITaxon_153135 a rdfs:Class ;
  rdfs:label "Gammaretrovirus" ;
  rdfs:subClassOf obo:NCBITaxon_327045 .

obo:NCBITaxon_724 a rdfs:Class ;
  rdfs:label "Haemophilus" ;
  rdfs:subClassOf obo:NCBITaxon_712 .

obo:VO_0011055 a rdfs:Class ;
  rdfs:label "VP1 from Canine parvovirus" ;
  rdfs:comment "This study shows that a plasmid DNA (pGT36VP1) encoding the full length VP1 region of canine parvovirus (CPV) induces immunity that protects dogs against challenge with virulent virus [PubMed: 9569471]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010807 .

obo:VO_0005422 a rdfs:Class ;
  rdfs:label "SLA-LSQ vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0003545 a rdfs:Class ;
  rdfs:label "Lyssavirus vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Lyssavirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0000598 a rdfs:Class ;
  rdfs:label "whole organism vaccine" ;
  rdfs:comment "A vaccine that uses whole organism as its component" ;
  rdfs:subClassOf obo:VO_0005505 .

obo:VO_0016327 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 3 by Mtk" ;
  rdfs:subClassOf obo:VO_0015937 .

obo:VO_0004376 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine pUB-ASP-2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0004673 a rdfs:Class ;
  rdfs:label "quadrivalent influenza vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003495 .

obo:VO_0000479 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae cell membrane vaccine (CM-Hi)" ;
  rdfs:subClassOf obo:VO_0000471 .

obo:VO_0017517 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 50" ;
  rdfs:subClassOf obo:VO_0017506 .

obo:VO_0004626 a rdfs:Class ;
  rdfs:label "LT-BCG- Ag85B /Rv3425 vaccine" ;
  rdfs:subClassOf obo:VO_0003130 .

obo:VO_0010768 a rdfs:Class ;
  rdfs:label "Hantavirus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0010320 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis Recombinant Fusion Protein Fhbp Group B vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0010448 a rdfs:Class ;
  rdfs:label "licensed human rabies virus vaccine" ;
  rdfs:comment "Rabies virus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000650 .

obo:VO_0020415 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020469 .

obo:VO_0015102 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Havpur] Box of 10" ;
  rdfs:subClassOf obo:VO_0015099 , obo:VO_0015104 , obo:VO_0015258 .

obo:VO_0018091 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0018084 , obo:VO_0018170 .

obo:VO_0017482 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017684 .

obo:VO_0011391 a rdfs:Class ;
  rdfs:label "Bordetella pertussis DNA vaccine encoding Prn" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000765 .

obo:VO_0001084 a rdfs:Class ;
  rdfs:label "baculovirus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a baculovirus as the vector " ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0001057 a rdfs:Class ;
  rdfs:label "Coxsackievirus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a Coxsackievirus strain" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0003769 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003767 .

obo:VO_0020716 a rdfs:Class ;
  rdfs:label "BCG, live, Connaught strain 20000 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0020715 .

obo:VO_0001887 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002338 .

obo:VO_0016600 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Twinrix]" ;
  rdfs:subClassOf obo:VO_0016591 , obo:VO_0016606 .

obo:VO_0018147 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 20" ;
  rdfs:subClassOf obo:VO_0018144 , obo:VO_0018157 .

obo:VO_0000857 a rdfs:Class ;
  rdfs:label "correlated profile of immune protection" ;
  rdfs:comment "Measurement process profile determined by the measurement data generated from a measurement process which indicates the degree of immunological protection in the vaccine recipient." ;
  rdfs:subClassOf obo:BFO_0000144 .

obo:VO_0003848 a rdfs:Class ;
  rdfs:label "IPOL vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003846 .

obo:VO_0017007 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017003 , obo:VO_0017020 , obo:VO_0017491 .

obo:VO_0018547 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML Injectable Suspension [Cervarix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018546 , obo:VO_0018549 .

obo:VO_0016408 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1 by GSK" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0010108 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii MIC8" ;
  rdfs:comment "A MIC8 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0002824 a rdfs:Class ;
  rdfs:label "live attenuated Brucella abortus with deletion of znuA vaccine" ;
  rdfs:comment "Deletion of gene znuA attenuates Brucella abortus and this live attenuated vaccine was challenged in mice. These mice showed significantly fewer spenic CFU" ;
  rdfs:subClassOf obo:VO_0001134 .

obo:NCBITaxon_3052518 a rdfs:Class ;
  rdfs:label "Orthonairovirus haemorrhagiae" ;
  rdfs:subClassOf obo:NCBITaxon_1980410 .

obo:VO_0011328 a rdfs:Class ;
  rdfs:label "AMN1" ;
  rdfs:comment "C57BL/6 mice immunized with rAMN1 showed a significant reduction of the fungal burden in their lungs at 90 days postchallenge compared to the control mice at 15 days [PubMed: 16369008]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010853 .

obo:VO_0002721 a rdfs:Class ;
  rdfs:label "gH from Herpes simplex virus type 1 and 2" ;
  rdfs:comment "A gH mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001437 .

obo:VO_0000390 a rdfs:Class ;
  rdfs:label "obsolete birds vaccine" ;
  rdfs:comment "Vaccine that used for immunizing birds." .

obo:VO_0020835 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b 0.05 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020836 .

obo:VO_0002071 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 12J5.40)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002367 , obo:VO_0007748 .

obo:VO_0004125 a rdfs:Class ;
  rdfs:label "recombinant VEE Replicons expressing MBGV GP vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012163 .

obo:VO_0000096 a rdfs:Class ;
  rdfs:label "Adenovirus Type 4 and Type 7 Vaccine, Live, Oral" ;
  rdfs:subClassOf obo:VO_0000037 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 .

obo:VO_0015610 a rdfs:Class ;
  rdfs:label "1 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015558 , obo:VO_0015589 , obo:VO_0015657 .

obo:VO_0011447 a rdfs:Class ;
  rdfs:label "obsolete Francisella tularensis DNA vaccine rLm/iglC" .

obo:VO_0000350 a rdfs:Class ;
  rdfs:label "live virulent vaccine role" ;
  rdfs:comment "Vaccine role that is characteristic of a live virulent vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0001631 a rdfs:Class ;
  rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1235.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:DOID_0080600 a rdfs:Class ;
  rdfs:label "COVID-19"@en ;
  rdfs:comment "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2, a subtype of Betacoronavirus pandemicum."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0021117 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:VO_0015321 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0003432 , obo:VO_0010745 .

obo:VO_0007509 a rdfs:Class ;
  rdfs:label "Melan-A/MAGE-3.DP4 peptide vaccine" ;
  rdfs:comment "Gene name: MAGEA3" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0016390 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015952 .

obo:VO_0010168 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b vaccine, PRP-OMP conjugate" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010437 .

obo:VO_0020797 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 CELLS Injectable Suspension [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020795 , obo:VO_0020796 , obo:VO_0020807 .

obo:VO_0002021 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Escherichia Coli Bacterin (USDA: 4585.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0000974 , obo:VO_0002377 .

obo:DOID_17 a rdfs:Class ;
  rdfs:label "musculoskeletal system disease"@en ;
  rdfs:comment "A disease of anatomical entity that occurs in the muscular and/or skeletal system."@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:VO_0015556 a rdfs:Class ;
  rdfs:label "Haemophilus B Conjugate Vaccine / Hepatitis B Surface Antigen Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000746 , obo:VO_0010439 , obo:VO_0020836 .

obo:VO_0007730 a rdfs:Class ;
  rdfs:label "RAS peptide cancer vaccine TG01" ;
  rdfs:comment "A cancer vaccine containing seven 17 amino acids long synthetic RAS oncogene-encoded peptides representing the most common codon 12 and 13 oncogenic mutations in Kirsten rat sarcoma viral oncogene homolog (KRAS), with potential immunomodulating and antineoplastic activities. The vaccine may stimulate a specific CD4-positive helper T-lymphocyte- and cytotoxic T-lymphocyte (CTL)-mediated immune response against RAS mutant-specific-expressing cancer cells, resulting in an inhibition of tumor cell proliferation and tumor cell death. The vaccine can be given in combination with Balstilimab and QS-21 for patients with pancreatic cancer to increase efficacy. " ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005430 , obo:VO_0007657 .

obo:VO_0016373 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 20 by Veron" ;
  rdfs:subClassOf obo:VO_0016037 .

obo:VO_0007529 a rdfs:Class ;
  rdfs:label "obsolete mRNA-Electroporated Dendritic Cells Vaccine" .

obo:NCBITaxon_28216 a rdfs:Class ;
  rdfs:label "Betaproteobacteria" ;
  rdfs:subClassOf obo:NCBITaxon_1224 .

obo:VO_0005485 a rdfs:Class ;
  rdfs:label "bladder cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against bladder cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0017363 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Prefilled Syringe [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0017361 .

obo:VO_0000931 a rdfs:Class ;
  rdfs:label "vaccine residual protein from cell culture" ;
  rdfs:comment "a cell culture residual in vaccine that is residual protein from cell culture. " ;
  rdfs:subClassOf obo:VO_0000856 .

obo:VO_0016598 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Paediatric] Box of 1" ;
  rdfs:subClassOf obo:VO_0016586 , obo:VO_0016593 , obo:VO_0016602 .

obo:VO_0019581 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2022 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020494 .

obo:VO_0020117 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML / mumps virus vaccine live, Jeryl Lynn strain 25000 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML Injection [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0000069 , obo:VO_0020116 .

obo:VO_0001884 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4089.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002336 .

obo:VO_0004638 a rdfs:Class ;
  rdfs:label "ALVAC-SIV/gp120 vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0007366 a rdfs:Class ;
  rdfs:label "Cyclin B1 Peptide-pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with cyclin B1 peptide, with potential immunostimulatory and antineoplastic activities. Upon administration, cyclin B1 peptide-pulsed autologous dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and anti-cyclin B1 antibody responses against cyclin B1-expressing cancer cells, resulting in tumor cell lysis. Cyclin B1, a key regulator of the cell cycle and cell division, is overexpressed in a variety of cancer cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0018080 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0018052 , obo:VO_0018160 .

obo:VO_0007243 a rdfs:Class ;
  rdfs:label "ALVAC-CEA B7.1 Vaccine" ;
  rdfs:comment "A cancer vaccine that uses a viral vector system derived from the canarypox virus engineered to target the carcinoembryonic antigen (CEA). It causes infected cells to temporarily display CEA and activates the immune system to attack the tumor cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0004046 a rdfs:Class ;
  rdfs:label "Leishmania major DNA vaccine encoding Gp63" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001231 .

obo:VO_0000271 a rdfs:Class ;
  rdfs:label "Francisella tularensis vaccine LVS" ;
  rdfs:comment "A live attenuated Francisella tularensis vaccine. It is available in American Type Culture Collection with ATCC ID: 29684." ;
  rdfs:subClassOf obo:VO_0000152 , obo:VO_0001217 .

obo:VO_0016333 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Europharma" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0001921 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Killed Virus Vaccine (USDA: 1175.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0002353 .

obo:VO_0002218 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4659.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002425 , obo:VO_0007748 .

obo:VO_0020236 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain 500000000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020237 .

obo:VO_0001319 a rdfs:Class ;
  rdfs:label "nanoemulsion vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant and is made from non-toxic lipid droplets a few hundred nanometers in diameter and made from surfactants approved for human consumption and common food substances that are 'Generally Recognized as Safe' (GRAS) by the FDA." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:NCBITaxon_9612 a rdfs:Class ;
  rdfs:label "Canis lupus" ;
  rdfs:subClassOf obo:NCBITaxon_9611 .

obo:VO_0002140 a rdfs:Class ;
  rdfs:label "Fowl Pox-Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 15E2.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002444 , obo:VO_0007748 .

obo:VO_0016791 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016729 .

obo:VO_0002312 a rdfs:Class ;
  rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49G6.22)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002465 , obo:VO_0007748 .

obo:VO_0016200 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015902 .

obo:VO_0020562 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Stada] Box of 10" ;
  rdfs:subClassOf obo:VO_0020561 , obo:VO_0020603 , obo:VO_0020864 .

obo:VO_0017887 a rdfs:Class ;
  rdfs:label "COVID-19 vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005264 .

obo:VO_0018469 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0018454 .

obo:VO_0020066 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0000710 a rdfs:Class ;
  rdfs:label "Brucella melitensis strain Rev. 1 vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000647 , obo:VO_0001135 .

obo:VO_0007153 a rdfs:Class ;
  rdfs:label "PSA/IL-2/GM-CSF Vaccine" ;
  rdfs:comment "A prostate cancer vaccine containing prostate specific antigen (PSA) combined with the cytokines, interleukin-2 (IL-2) and granulocyte macrophage-colony-stimulating factor (GM-CSF), with potential antineoplastic activity. Upon intradermal vaccination, PSA/IL-2/GM-CSF vaccine may activate the immune system to induce a cytotoxic T-cell (CTL) response against prostate cancer cells expressing this antigen, thereby decreasing tumor cell growth. PSA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed by prostate cancer cells. IL-2 stimulates natural killer (NK) cells and cytotoxic T-cells against the PSA-expressing tumor cells. GM-CSF promotes antigen presentation to dendritic cells and further stimulates a tumor-specific cytotoxic T-lymphocyte (CTL) response." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0007547 a rdfs:Class ;
  rdfs:label "LMP-2:419-427 Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine containing amino acids residues from 419 through 427 of the latent membrane protein-2 (LMP-2) of the Epstein-Barr virus (EBV) with potential immunostimulating and antineoplastic activities. LMP-2, an EBV transmembrane protein, is expressed in various malignancies including nasopharyngeal cancer and EBV-positive Hodgkin's disease. Vaccination with the LMP-2:49-427 peptide may boost the immune system to mount a specific cytotoxic T-lymphocyte response against LMP-2 producing cells, resulting in cell lysis and inhibition of cancer cell proliferation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005498 , obo:VO_0007657 .

obo:VO_0015130 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe [Epaxal] Box of 10" ;
  rdfs:subClassOf obo:VO_0015127 , obo:VO_0015132 , obo:VO_0015295 .

obo:NCBITaxon_8015 a rdfs:Class ;
  rdfs:label "Salmonidae" ;
  rdfs:subClassOf obo:NCBITaxon_1489388 .

obo:VO_0001109 a rdfs:Class ;
  rdfs:label "MVTT vaccine vector" ;
  rdfs:comment "a vaccinia virus vector that uses the MVTT vaccine strain as the vector. MVTT is an attenuated vaccine strain. " ;
  rdfs:subClassOf obo:VO_0000600 .

obo:VO_0004148 a rdfs:Class ;
  rdfs:label "DNA vaccine co-expressing A85A and caspase-3" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:VO_0001444 a rdfs:Class ;
  rdfs:label "SARS-CoV gene" ;
  rdfs:comment "A viral gene that is from SARS-CoV." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0007172 a rdfs:Class ;
  rdfs:label "Renal Cell Carcinoma Peptides Vaccine IMA901" ;
  rdfs:comment "A multipeptide cancer vaccine targeting renal cell carcinoma with potential immunopotentiating activity. Renal cell carcinoma peptides vaccine IMA901 consists of 10 different synthetic tumor-associated peptide (TUMAP) antigens (9 HLA-class I-binding and 1 HLA class II-binding); endogenously, these TUMAPs are expressed by the majority of renal cell carcinomas. Vaccination with this agent may significantly increase host cytotoxic T-lymphocyte (CTL) immune responses against tumor cells expressing these peptide antigens." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0020781 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 ORGANISMS [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020780 .

obo:VO_0000545 a rdfs:Class ;
  rdfs:label "human vaccinee population" ;
  rdfs:comment "a population of human beings who are vaccinated." ;
  rdfs:subClassOf obo:VO_0000546 .

obo:VO_0003821 a rdfs:Class ;
  rdfs:label "influenza B virus B/Colorado/06/2017 antigen" ;
  rdfs:comment "RXAUI: 10329696" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:VO_0020481 a rdfs:Class ;
  rdfs:label "Fluzone 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 , obo:VO_0010416 .

obo:VO_0016931 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 2 LFU/ML / tetanus toxoid vaccine, inactivated 2 LFU/ML Injection Box of 10 by Massbiologics" ;
  rdfs:subClassOf obo:VO_0016930 .

obo:VO_0016362 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0020857 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluad] Box of 10" ;
  rdfs:subClassOf obo:VO_0020856 , obo:VO_0020884 .

obo:VO_0004545 a rdfs:Class ;
  rdfs:label "Borrelia pertussis DNA vaccine pcDNA/S1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000765 .

obo:VO_0007128 a rdfs:Class ;
  rdfs:label "WT1 Peptide Vaccine WT2725" ;
  rdfs:comment "A peptide cancer vaccine comprised of a peptide derived from Wilms tumor gene 1 (WT1) protein, with potential immunomodulating and antineoplastic activities. Upon administration, WT2725 may induce a specific cytotoxic T-lymphocyte (CTL) response against WT1-overexpressing tumor cells. WT1 protein, a zinc finger DNA-binding protein, is overexpressed in leukemic cells and in a vast number of non-hematological solid tumors." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0001961 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica Bacterin (USDA: 4477.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002363 .

obo:VO_0017263 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Adacel]" ;
  rdfs:subClassOf obo:VO_0000005 , obo:VO_0018772 .

obo:VO_0010632 a rdfs:Class ;
  rdfs:label "country" ;
  rdfs:subClassOf obo:BFO_0000029 .

obo:VO_0002493 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis-Marek's Disease Serotype 3, Live Marek's Disease Vector Vaccine (USDA: 16J1.R3)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002441 , obo:VO_0007748 .

obo:VO_0000331 a rdfs:Class ;
  rdfs:label "pVCL(pCXN2-mVIN) DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015155 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by European" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0004706 a rdfs:Class ;
  rdfs:label "SG33-VP2/5 vaccine" ;
  rdfs:subClassOf obo:VO_0001476 , obo:VO_0001515 .

obo:VO_0019256 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019795 .

obo:PATO_0000047 a rdfs:Class ;
  rdfs:label "biological sex" ;
  rdfs:comment "An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:VO_0003942 a rdfs:Class ;
  rdfs:label "Human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003940 .

obo:VO_0015531 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution [Engerix B]" ;
  rdfs:subClassOf obo:VO_0010711 , obo:VO_0015500 .

obo:VO_0002848 a rdfs:Class ;
  rdfs:label "obsolete KKF24" ;
  rdfs:comment "An iglC mutant is highly attenuated in mice. Inoculated mice were challenged 30 days later with wild type F. tularensis and were highly protected" .

obo:VO_0016376 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015941 .

obo:VO_0020945 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML [FluMist Quadrivalent]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0000982 , obo:VO_0004914 .

obo:VO_0017796 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 600 UNT/ML Injectable Suspension [Acel-P]" ;
  rdfs:subClassOf obo:VO_0017794 , obo:VO_0017795 , obo:VO_0017800 .

obo:VO_0001789 a rdfs:Class ;
  rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.00)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001456 , obo:VO_0007748 .

obo:VO_0020667 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution Box of 6" ;
  rdfs:subClassOf obo:VO_0020656 , obo:VO_0020709 .

obo:VO_0003398 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003399 .

obo:VO_0010751 a rdfs:Class ;
  rdfs:label "bacterium protein" ;
  rdfs:comment "a protein from a bacterium" ;
  rdfs:subClassOf obo:PR_000000001 .

obo:VO_0005480 a rdfs:Class ;
  rdfs:label "Plasmodium chabaudi vaccine" ;
  rdfs:comment "a malaria vaccine that protects against malaria caused by Plasmodium chabaudi." ;
  rdfs:subClassOf obo:VO_0000761 .

obo:VO_0001813 a rdfs:Class ;
  rdfs:label "West Nile Virus Killed Virus Vaccine (USDA: 1995.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000752 , obo:VO_0001475 , obo:VO_0007748 .

obo:NCBITaxon_2759 a rdfs:Class ;
  rdfs:label "Eukaryota" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:VO_0011301 a rdfs:Class ;
  rdfs:label "T. cruzi PAR1" ;
  rdfs:comment "C57BL/6 mice were immunized s.c. with recombinant PFR-1 (PAR1) protein co-adsorbed to alum with rIL-12. rPFR-1 immunized animals were able to successfully resolve parasitemia by day 30 p.i., with the peak parasitemia occurring between days 17 and 21 p.i. [PubMed: 12798650]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0020500 a rdfs:Class ;
  rdfs:label "hepatitis C virus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0016581 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Adult]" ;
  rdfs:subClassOf obo:VO_0016568 , obo:VO_0016585 .

obo:DOID_3118 a rdfs:Class ;
  rdfs:label "hepatobiliary disease"@en ;
  rdfs:comment "A gastrointestinal system disease that is located_in the liver and/or biliary tract."@en ;
  rdfs:subClassOf obo:DOID_77 .

obo:VO_0015176 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015265 .

obo:VO_0015571 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015491 , obo:VO_0015549 .

obo:VO_0004882 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.1 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.1 MG/ML [Menomune A/C/Y/W-135]" ;
  rdfs:subClassOf obo:VO_0000072 .

obo:VO_0010023 a rdfs:Class ;
  rdfs:label "Leishmania infantum HSP70 II" ;
  rdfs:comment "A HSP70 II protein that is part of Leishmania  infantum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010836 .

obo:VO_0020243 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Injectable Suspension [Prevnar]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0001971 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1187.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0004726 a rdfs:Class ;
  rdfs:label "ALVAC-BTV-VP2/VP5 vaccine" ;
  rdfs:subClassOf obo:VO_0001515 .

obo:VO_0018372 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG" ;
  rdfs:subClassOf obo:VO_0003345 .

obo:VO_0016669 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016626 .

obo:VO_0020404 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 1000000000 UNT/ML Injectable Suspension by Aventis" ;
  rdfs:subClassOf obo:VO_0020385 .

obo:VO_0021034 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0021032 , obo:VO_0021040 .

obo:VO_0018575 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension [Stamaril] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018574 .

obo:OPL_0000375 a rdfs:Class ;
  rdfs:label "Plasmodium berghei lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Plasmodium berghei." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0010071 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi G1" ;
  rdfs:comment "A G1 protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0005361 a rdfs:Class ;
  rdfs:label "Montanide IMS 1313 vaccine adjuvant" ;
  rdfs:comment "A Montanide vaccine adjuvant that is a water-dispersed liquid IMS 1313 nanoparticle combined with an immuno-stimulating compound." ;
  rdfs:subClassOf obo:VO_0001271 .

obo:NCBITaxon_11040 a rdfs:Class ;
  rdfs:label "Rubivirus" ;
  rdfs:subClassOf obo:NCBITaxon_2732543 .

obo:VO_0011007 a rdfs:Class ;
  rdfs:label "YPO0612" ;
  rdfs:comment "Using a mouse plague model, YPO0612 may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0006000 a rdfs:Class ;
  rdfs:label "adenovirus vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000037 , obo:VO_0000455 , obo:VO_0000635 .

obo:VO_0016217 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:VO_0004780 a rdfs:Class ;
  rdfs:label "NYVAC-JEV- prM/E/ NS1 vaccine" ;
  rdfs:subClassOf obo:VO_0000665 .

obo:VO_0007478 a rdfs:Class ;
  rdfs:label "GM-CSF, IL-12 and GM-CSF+IL-12 genetically modified tumor cell vaccine" ;
  rdfs:comment "Used C57BL/6 mice and irradiated B16 tumor cells expressing granulocyte and macrophage colony-stimulating factor (GM-CSF), interleukin-12 (IL-12) or both. Tumor was transplanted by the injection of wild-type B16 cells. Tumor growth and survival were measured to evaluate the efficacy of vaccination. Specific humoral response and immunoglobulin G (IgG) switch were evaluated measuring total IgG and IgG1 and IgG2a subtypes against tumor membrane proteins of B16 cells" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0003578 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0015080 .

obo:VO_0018418 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 9V vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003561 .

obo:VO_0016506 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Mtk" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:VO_0000469 a rdfs:Class ;
  rdfs:label "autogenous bacterin vaccine" ;
  rdfs:comment "a bacterial vaccine that uses bacterin from a bacterial strain isolated from a herd with a purpose to generate hard-specific vaccine. " ;
  rdfs:subClassOf obo:VO_0000165 .

obo:VO_0015822 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] by Merck" ;
  rdfs:subClassOf obo:VO_0015615 .

obo:VO_0000071 a rdfs:Class ;
  rdfs:label "Menactra vaccine" ;
  rdfs:comment "Menactra, Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine, is indicated for active immunization to prevent invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, Y and W-135." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0000714 , obo:VO_0003441 , obo:VO_0010444 .

obo:VO_0007405 a rdfs:Class ;
  rdfs:label "inactivated vaccinia virus vaccine" ;
  rdfs:comment "A poxvirus made non-infectious by ultraviolet light or other inactivation methods in order to reduce its pathogenicity. In cancer gene therapy, inactivated vaccinia virus may be used as a vector to express a protein that kills tumor cells or elicits specific anti-tumor immunity. In a cancer vaccine application, tumor cells taken from the host may be adsorbed with inactivated vaccinia virus and returned to the host, where the modified tumor cells may stimulate an anti-tumor immune response." ;
  rdfs:subClassOf obo:VO_0000315 , obo:VO_0007657 .

obo:VO_0011261 a rdfs:Class ;
  rdfs:label "Nef" ;
  rdfs:comment "Study compared the handling of overlapping 24-mer peptides from HIV Nef either mixed or covalently linked in tandem in one protein.  With adjuvant, overlapping peptides were capable of protecting Balb/c mice against lethal viral challenge with 3 108 plaque forming units of vv-nef, whereas the intact protein was less protective [PubMed: 19193636]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010767 .

obo:NCBITaxon_1639 a rdfs:Class ;
  rdfs:label "Listeria monocytogenes" ;
  rdfs:subClassOf obo:NCBITaxon_1385 .

obo:VO_0003150 a rdfs:Class ;
  rdfs:label "Hepatitis B surface antigen vaccine" ;
  rdfs:comment "A Hepatitis B virus vaccine that uses recombinant Hepatitis B surface antigen as the antigen" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000644 , obo:VO_0010439 .

obo:VO_0007045 a rdfs:Class ;
  rdfs:label "synthetic hTERT DNA vaccine INO-1400" ;
  rdfs:comment "A DNA vaccine consisting of a plasmid encoding the full-length sequence of the tumor-associated antigen (TAA) human telomerase reverse transcriptase (hTERT), which is the catalytic subunit of human telomerase and synthesizes telomeric DNA at the chromosome ends, containing two immunogenic mutations, with potential immunostimulating and antineoplastic activities. Upon intradermal vaccination of the hTERT-encoding DNA vaccine INO-1400 in combination with electroporation, hTERT protein is expressed and activates the immune system to mount a cytotoxic T-cell (CTL) response against telomerase-expressing tumor cells, which may result in tumor cell death. Telomerase prolongs the functional lifespan of cells via the restoration and maintenance of telomere length. Abnormally activated in tumorigenesis, telomerase is expressed in the majority of human cancer cells, but its expression is low or non-existent in normal cells." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0017434 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.015 MG / Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.25 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0017672 , obo:VO_0020836 .

obo:VO_0019911 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluzone High-Dose 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020485 .

obo:VO_0003257 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:NCBITaxon_5809 a rdfs:Class ;
  rdfs:label "Sarcocystidae" ;
  rdfs:subClassOf obo:NCBITaxon_423054 .

obo:VO_0003617 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2015-2016 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003616 .

obo:VO_0005386 a rdfs:Class ;
  rdfs:label "3M-052-SE vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0020087 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0020018 .

obo:VO_0018807 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015054 .

obo:VO_0010325 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated vaccine" ;
  rdfs:subClassOf obo:VO_0000646 , obo:VO_0000712 .

obo:VO_0019304 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Fluarix 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019301 , obo:VO_0020316 .

obo:OPL_0000169 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi trypomastigote stage" ;
  rdfs:comment "A trypomastigote stage in the Trypanosoma cruzi lifecycle that occurs either in the vertebrate host or an insect vector." ;
  rdfs:subClassOf obo:OPL_0000033 , obo:OPL_0000185 .

obo:VO_0001492 a rdfs:Class ;
  rdfs:label "avian polyomavirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Avian Polyomavirus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 , obo:VO_0001461 .

obo:VO_0010172 a rdfs:Class ;
  rdfs:label "hepatitis B vaccine (recombinant), CpG adjuvanted" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0010439 .

obo:VO_0019535 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine Injectable Suspension [Recombivax]" ;
  rdfs:subClassOf obo:VO_0003416 .

obo:VO_0000830 a rdfs:Class ;
  rdfs:label "rF1 + rV vaccine" ;
  rdfs:comment "A Y. pestis subunit vaccine that uses recombinant F1 and V antigens. PMID:312163." ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0004653 a rdfs:Class ;
  rdfs:label "AcHERV-sH1N1-HA vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0002754 a rdfs:Class ;
  rdfs:label "obsolete PE2 from Western equine encephalomyelitis virus" ;
  rdfs:comment "A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur" .

obo:VO_0011016 a rdfs:Class ;
  rdfs:label "pYV0055" ;
  rdfs:comment "Complexes of YopB (pYV0055), YopD, and YopE (BDE) secreted by Yersinia pseudotuberculosis were purified by affinity chromatography and used as immunogens to determine if antibodies to the translocon could provide protection against Y. pestis in mice. The YopB protein or a complex of YopB and YopD (BD) was purified and determined by vaccination to be immunogenic in mice. Mice actively vaccinated with BD or passively vaccinated with anti-BD serum were protected against lethal challenge with F1(-) Y. pestis [PubMed: 18765742]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010796 .

obo:VO_0001399 a rdfs:Class ;
  rdfs:label "fusion conjugate protein vaccine" ;
  rdfs:comment "a conjugate vaccine that conjugate more than one open reading frames of protective antigens or conjugate a protective antigen to a carrier protein." ;
  rdfs:subClassOf obo:VO_0000195 .

obo:VO_0003188 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine foreign to USA" ;
  rdfs:comment "A Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0000946 , obo:VO_0003444 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010445 , obo:VO_0010447 .

obo:DOID_2043 a rdfs:Class ;
  rdfs:label "hepatitis B"@en ;
  rdfs:comment "A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0004137 a rdfs:Class ;
  rdfs:label "heterologous MARV protein VLP vaccine" ;
  rdfs:subClassOf obo:VO_0012163 .

obo:VO_0021147 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.12 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 31 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 33 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 45 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 52 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 58 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.06 MG/ML Prefilled Syringe [Gardasil 9]" ;
  rdfs:subClassOf obo:VO_0003075 .

obo:VO_0007117 a rdfs:Class ;
  rdfs:label "tyrosinase-KLH vaccine" ;
  rdfs:comment "A peptide vaccine containing a tyrosinase epitope conjugated with keyhole lymphocyte hemocyanin (KLH) with potential antineoplastic activity. Tyrosinase, one of the melanoma differentiation antigens, is the rate-limiting enzyme for melanin synthesis. This tyrosine epitope is conjugated with KLH, which serves as an immunostimulant and a hapten carrier, to enhance immune recognition. Vaccination with tyrosinase-KLH peptide vaccine may produce anti-tyrosinase antibodies as well as elicit a cytotoxic T lymphocyte (CTL) response against cells expressing tyrosinase antigen, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0015218 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015217 , obo:VO_0015227 , obo:VO_0015308 .

obo:VO_0004808 a rdfs:Class ;
  rdfs:label "APSV Wetvax vaccine" ;
  rdfs:subClassOf obo:VO_0000433 , obo:VO_0000455 , obo:VO_0010452 .

obo:VO_0010905 a rdfs:Class ;
  rdfs:label "BoNT/C(Hc50)" ;
  rdfs:comment "Researchers constructed a replication-incompetent adenovirus encoding a synthesized codon-optimized gene for expression of the heavy chain C-fragment (H(C)50) of botulinum neurotoxin type C (BoNT/C).  After a single dose of 2 x 10^7pfu adenoviral vectors in a mouse model, the animals were completely protected against intraperitoneal challenge with 100 x MLD(50) of active BoNT/C  [PubMed: 17897756]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010762 .

obo:VO_0007444 a rdfs:Class ;
  rdfs:label "human papillomavirus  16 E7:86-93 peptide vaccine" ;
  rdfs:comment "A synthetic peptide vaccine consisting of amino acids 86 through 93 (TLGIVCPI) of the viral oncoprotein human papillomavirus (HPV) 16 E7. Vaccination with HPV-16 E7:86-93 peptide, which binds to HLA-A* 0201 molecule, may stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV-16 E7." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0012168 a rdfs:Class ;
  rdfs:label "Herpes simplex virus type 1 and 2 vaccine" ;
  rdfs:comment "A vaccine that protects against Herpes simplex virus type 1 and 2." ;
  rdfs:subClassOf obo:VO_0000727 .

obo:VO_0016058 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0003420 .

obo:VO_0007142 a rdfs:Class ;
  rdfs:label "VEGFR2-169 Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine containing an HLA-A*2402-restricted epitope of vascular endothelial growth factor receptor (VEGFR) 2 with potential immunostimulatory and antineoplastic activities. Upon administration, VEGFR2-169 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against VEGFR2-expressing tumor cells. VEGFR2, a receptor tyrosine kinase, is overexpressed by a variety of tumor types; overexpression is associated with tumor cell proliferation and tumor angiogenesis. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenic peptide immunogenicity." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005430 , obo:VO_0007657 .

obo:NCBITaxon_80840 a rdfs:Class ;
  rdfs:label "Burkholderiales" ;
  rdfs:subClassOf obo:NCBITaxon_28216 .

obo:VO_0020034 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe [Fluvirin 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020028 , obo:VO_0020355 .

obo:VO_0003538 a rdfs:Class ;
  rdfs:label "Papillomaviridae vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Papillomaviridae." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0020897 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020887 , obo:VO_0020909 .

obo:VO_0002150 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Conn Type, Live Virus Vaccine (USDA: 1761.13)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0020098 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0020097 .

obo:VO_0020566 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippeimpfstoff Ratiopharm] Box of 10" ;
  rdfs:subClassOf obo:VO_0020565 , obo:VO_0020603 , obo:VO_0020866 .

obo:VO_0007384 a rdfs:Class ;
  rdfs:label "gp96-secreting Allogeneic Bladder Cancer Cell Vaccine HS-410" ;
  rdfs:comment "An allogeneic urothelial bladder cancer cell vaccine expressing a recombinant secretory form of the immunoadjuvant heat shock protein gp96 fused with an immunoglobulin Fc domain (gp96-Ig) protein, with potential antineoplastic activity. Upon administration of the gp96-Ig-secreting allogeneic bladder cancer cell vaccine HS-410, the live, irradiated tumor cells continuously secrete gp96-Ig along with its chaperoned tumor associated antigens (TAAs). This enhances antigen cross presentation to cytotoxic T-lymphocytes (CTLs) and, upon expansion, leads to the induction of a potent CTL response against the TAAs on the endogenous bladder cancer cells. This vaccine also induces a memory T cell response that could fight recurring cancer cells. gp96-Ig is constructed by replacing the KDEL endoplasmic reticulum (ER) retention sequence of gp96 with the Fc portion of the IgG1 protein. This allows for gp96, normally an ER-resident chaperone peptide, to be released from cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0004014 a rdfs:Class ;
  rdfs:label "Neisseria miningitidis TBP2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0016633 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0016564 , obo:VO_0016617 .

obo:VO_0020738 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain Injectable Suspension [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020737 .

obo:VO_0019229 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0010428 , obo:VO_0019750 .

obo:VO_0017341 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0017808 .

obo:VO_0019807 a rdfs:Class ;
  rdfs:label "influenza A virus A/Idaho/07/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Indiana/08/2018 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Injectable Suspension [Flucelvax Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020332 .

obo:VO_0007619 a rdfs:Class ;
  rdfs:label "IDD-3 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0017775 a rdfs:Class ;
  rdfs:label "Bordetella Pertussis Filamentous Haemagglutinin Antigen" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:OGG_3000886960 a rdfs:Class ;
  rdfs:label "lysA" ;
  rdfs:comment "Diaminopimelate decarboxylase LysA (DAP decarboxylase)" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0018894 a rdfs:Class ;
  rdfs:label "influenza A virus A/Washington/19/2020 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0000070 a rdfs:Class ;
  rdfs:label "M-M-Vax vaccine" ;
  rdfs:comment "A Measles-Mumps vaccine that is manufactured by Merck and used for human. " ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000736 , obo:VO_0001220 , obo:VO_0010441 , obo:VO_0010442 .

obo:VO_0003302 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 18 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003299 , obo:VO_0010446 .

obo:UBERON_0001981 a rdfs:Class ;
  rdfs:label "blood vessel" ;
  rdfs:comment "A vessel through which blood circulates in the body." ;
  rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0010000 .

obo:VO_0019792 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003703 .

obo:VO_0015643 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015670 .

obo:VO_0007265 a rdfs:Class ;
  rdfs:label "anti-idiotypic monoclonal antibody BEC2 vaccine" ;
  rdfs:comment "A murine anti-idiotypic monoclonal antibody (anti-Id MoAb) that is directed against an idiotype mimicking a disialoganglioside GD3. GD3 represents a major surface marker on most human melanoma cells. Due to poor immunogenicity of GD3, anti-Id MoAb BEC2 (Ab2) was raised against a mouse anti-GD3 MoAb, R24 (Ab1). This anti-Id MoAb was shown to be functionally mimicking GD3 in stimulating an immune response to produce Ab3 that may be used in combination with other adjuvants for treatment of melanomas." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0018735 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 2000000000 ORGANISMS Delayed Release Oral Capsule [Vivotif Berna]" ;
  rdfs:subClassOf obo:VO_0018733 , obo:VO_0018734 .

obo:NCBITaxon_35500 a rdfs:Class ;
  rdfs:label "Pecora" ;
  rdfs:subClassOf obo:NCBITaxon_91561 .

obo:OPL_0000026 a rdfs:Class ;
  rdfs:label "microgamete stage" ;
  rdfs:comment "A gamete stage in apicomplexan parasites when exflagellated microgametocyte divides into microgamete." ;
  rdfs:subClassOf obo:OPL_0000181 , obo:OPL_0000260 .

obo:VO_0017460 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 160 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017457 .

obo:VO_0018399 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003212 .

obo:VO_0004425 a rdfs:Class ;
  rdfs:label "Cancer DNA vaccine p.DOM-AH1 encoding fragment C" ;
  rdfs:comment "Gene name: Fragment C from tetanus toxin" ;
  rdfs:subClassOf obo:VO_0005489 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0018032 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML [Ipol]" ;
  rdfs:subClassOf obo:VO_0000054 , obo:VO_0018046 .

obo:VO_0016301 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 20 by Veron" ;
  rdfs:subClassOf obo:VO_0016029 .

obo:VO_0020593 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] Box of 50 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020592 .

obo:VO_0019368 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.0025 MG/ML Prefilled Syringe [Recombivax]" ;
  rdfs:subClassOf obo:VO_0019367 , obo:VO_0019519 .

obo:NCBITaxon_29459 a rdfs:Class ;
  rdfs:label "Brucella melitensis" ;
  rdfs:subClassOf obo:NCBITaxon_234 .

obo:VO_0005252 a rdfs:Class ;
  rdfs:label "ReCOV vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine by Jiangsu Rec-Biotechnology Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0015117 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by European" ;
  rdfs:subClassOf obo:VO_0015111 .

obo:VO_0017568 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0017567 , obo:VO_0017576 .

obo:DOID_0081267 a rdfs:Class ;
  rdfs:label "graft-versus-host disease"@en ;
  rdfs:comment "An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32."@en ;
  rdfs:subClassOf obo:DOID_2914 .

obo:NCBITaxon_11320 a rdfs:Class ;
  rdfs:label "Influenza A virus" ;
  rdfs:subClassOf obo:NCBITaxon_197911 .

obo:VO_0016264 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 3 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015922 .

obo:VO_0020139 a rdfs:Class ;
  rdfs:label "mumps virus vaccine live, Jeryl Lynn strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015056 .

obo:VO_0001374 a rdfs:Class ;
  rdfs:label "vaccinee" ;
  rdfs:comment "an organism that is vaccinated with a vaccine" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:VO_0002273 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4875.A0)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000539 , obo:VO_0000640 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0017134 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017133 , obo:VO_0017141 , obo:VO_0017598 .

obo:VO_0018089 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution [Priorix] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018088 .

obo:VO_0000030 a rdfs:Class ;
  rdfs:label "Decavac vaccine" ;
  rdfs:comment "Product Name: Tetanus & Diphtheria Toxoids Adsorbed for Adult Use" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0011415 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum subunit SE36 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000455 , obo:VO_0000534 .

obo:VO_0007197 a rdfs:Class ;
  rdfs:label "Adenovector Encoding MDA7 Vaccine" ;
  rdfs:comment "A nonreplicating adenoviral vector (adenovector) encoding the melanoma differentiation-associated 7 gene (MDA7) with potential antineoplastic activity. After intratumoral injection and adenovector-mediated gene transfer of MDA7 into tumor cells, the expressed MDA7 transgene may inhibit tumor cell proliferation and induce tumor cell apoptosis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0016025 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015666 , obo:VO_0015772 .

obo:VO_0019568 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluvirin 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003681 , obo:VO_0019544 .

obo:VO_0010426 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2010-2011" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0001900 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 11B5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0002344 .

obo:VO_0003978 a rdfs:Class ;
  rdfs:label "KINRIX vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003977 .

obo:VO_0003172 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Hepatitis B vaccine" ;
  rdfs:subClassOf obo:VO_0000738 , obo:VO_0010439 .

obo:VO_0005015 a rdfs:Class ;
  rdfs:label "pNGVL3 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pNGVL3.  This plasmid has a CMV promoter and kanamycin and ampicillin resistance genes." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015704 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 50" ;
  rdfs:subClassOf obo:VO_0015569 , obo:VO_0015793 .

obo:VO_0003195 a rdfs:Class ;
  rdfs:label "Acetone-Dried Typhoid Vi Polysaccharide vaccine" ;
  rdfs:comment "A polysaccharide vaccine to prevent typhoid caused Salmonella typhi. Acetone is used to inactivate culture, and dried." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0003443 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010451 .

obo:VO_0018078 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 25" ;
  rdfs:subClassOf obo:VO_0018052 , obo:VO_0018158 .

obo:VO_0010762 a rdfs:Class ;
  rdfs:label "Clostridium botulinum protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:VO_0015683 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015565 , obo:VO_0015776 .

obo:VO_0000835 a rdfs:Class ;
  rdfs:label "Epm vaccine" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000935 .

obo:VO_0004420 a rdfs:Class ;
  rdfs:label "IHNV DNA vaccine pCDNA-G encoding G" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012165 .

obo:VO_0019647 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0020320 .

obo:VO_0007599 a rdfs:Class ;
  rdfs:label "DLK1/EPHA2/HBB/NRP1/RGS5/TEM1 peptide-pulsed alpha-type-1 polarized dendritic cell vaccine" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0004275 a rdfs:Class ;
  rdfs:label "human apo B-100 peptide-2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0002793 .

obo:VO_0003189 a rdfs:Class ;
  rdfs:label "seasonal influenza virus vaccine foreign to USA" ;
  rdfs:comment "A seasonal Influenza virus vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0003444 , obo:VO_0010415 .

obo:VO_0001198 a rdfs:Class ;
  rdfs:label "pathogen strain for challenge datum" ;
  rdfs:comment "A measurement datum that represents a specific pathogen strain used for animal challenge study. Different pathogen strains can be represented using discretized digitals.  " ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0001362 a rdfs:Class ;
  rdfs:label "allergy vaccine" ;
  rdfs:comment "a vaccine that targets for allergy." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005503 .

obo:VO_0004094 a rdfs:Class ;
  rdfs:label "dVV-L vaccine" ;
  rdfs:subClassOf obo:VO_0000651 .

obo:VO_0019619 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020331 .

obo:VO_0017213 a rdfs:Class ;
  rdfs:label "10 ML tetanus toxoid vaccine, inactivated 8 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017212 , obo:VO_0017214 , obo:VO_0017587 .

obo:VO_0011142 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/chicken/Indonesia/7/2003(H5N1))" ;
  rdfs:comment "All specific-pathogen-free chickens immunized with (vFP2211) expressing a modified synthetic HA gene from H5N1 A/chicken/Indonesia/7/2003 were clinically protected from HPAI challenge [PubMed: 20521642]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0001608 a rdfs:Class ;
  rdfs:label "Avian Reovirus Killed Virus Vaccine (USDA: 1045.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001513 , obo:VO_0007748 .

obo:OPL_0000299 a rdfs:Class ;
  rdfs:label "Plasmodium hepatic schizont stage" ;
  rdfs:comment "A hepatic schizont stage in the Plasmodium lifecycle that occurs in the infected hepatocytes of a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000059 , obo:OPL_0000297 .

obo:VO_0021013 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0021011 , obo:VO_0021040 .

obo:VO_0002014 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4367.26)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002373 .

obo:VO_0000082 a rdfs:Class ;
  rdfs:label "Pediarix vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000714 , obo:VO_0000743 .

obo:OPL_0000327 a rdfs:Class ;
  rdfs:label "Plasmodium vivax sporozoite" ;
  rdfs:comment "A Plasmodium vivax is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector." ;
  rdfs:subClassOf obo:NCBITaxon_5855 , obo:OPL_0000278 .

obo:VO_0004799 a rdfs:Class ;
  rdfs:label "SAd-ME.TRAP vaccine" ;
  rdfs:subClassOf obo:VO_0000761 .

obo:VO_0007182 a rdfs:Class ;
  rdfs:label "RCAS-Akt Vaccine" ;
  rdfs:comment "A recombinant retroviral virus derived from SR-A strain of Rous sarcoma virus carrying a constitutively active form of the AKT Gene. The viral vector RCAS harbors a Replication Competent ALV Splice acceptor. This recombinant virus was use in animal model to study gliomagenesis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0004787 a rdfs:Class ;
  rdfs:label "dVV-HA5(H5N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0001671 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001488 , obo:VO_0007748 .

obo:VO_0015650 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015487 , obo:VO_0015588 .

obo:VO_0002787 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis RD1/panCD mutant vaccine" ;
  rdfs:comment "RD1 and panCD mutants in Mycobacterium tuberculosis were attenuated and provided protection in CD4-deficient mice against an aerosol challenge with virulent M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0003703 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0000983 , obo:VO_0010433 .

obo:VO_0002591 a rdfs:Class ;
  rdfs:label "clpB from Francisella tularensis" ;
  rdfs:comment "A clpB mutant in Francisella tularensis subspecies tularensis strain SCHU S4 was attenuated and provided protection against aerosol challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0011077 a rdfs:Class ;
  rdfs:label "SodB from F. tularensis SCHU S4" ;
  rdfs:comment "C57BL/6 mice were vaccinated intranasally (i.n.) with the sodB(Ft) mutant and challenged i.n. with lethal doses of F. tularensis SchuS4. SodB(Ft) vaccinated mice following SchuS4 challenge exhibited significantly reduced bacterial burden in lungs, liver and spleen, regulated production of pro-inflammatory cytokines and less severe histopathological lesions compared to the LVS vaccinated mice. The sodB(Ft) vaccination induced a potent humoral immune response and protection against SchuS4 required both CD4 and CD8 T cells in the vaccinated mice [PubMed: 18692537]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:VO_0001024 a rdfs:Class ;
  rdfs:label "inactivated avian influenza vaccine" ;
  rdfs:comment "an avian influenza vaccine that uses inactivated viral organism" ;
  rdfs:subClassOf obo:VO_0000461 , obo:VO_0001176 .

obo:DOID_7 a rdfs:Class ;
  rdfs:label "disease of anatomical entity"@en ;
  rdfs:comment "A disease that manifests in a defined anatomical structure."@en ;
  rdfs:subClassOf obo:DOID_4 .

obo:VO_0007344 a rdfs:Class ;
  rdfs:label "autologous tumor cell lysate vaccine" ;
  rdfs:comment "A cancer vaccine made from the patient's cancer cells that may make the body build an immune response and kill their tumor cells. The autologous tumor cell vaccine will be given together with adjuvant interferon gamma or sargramostim (GM-CSF) in patients with advanced cancer (breast, lung, prostate, colorectal, sarcoma, renal, melanoma). The vaccine uses irradiated autologous tumor cells and tumor lysate." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0001313 a rdfs:Class ;
  rdfs:label "Sclavo peptide vaccine adjuvant" ;
  rdfs:comment "A cytokine vaccine adjuvant that contains the 163-171 peptide of IL-1β." ;
  rdfs:subClassOf obo:VO_0001353 .

obo:VO_0020809 a rdfs:Class ;
  rdfs:label "BCG, live, Tice strain Injection [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0019412 .

obo:VO_0001031 a rdfs:Class ;
  rdfs:label "Salmonella typhimurium SL3261 vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector using a live attenuated Salmonella enterica strain SL3261." ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0015951 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [H B Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015640 , obo:VO_0015725 , obo:VO_0016040 .

obo:VO_0005308 a rdfs:Class ;
  rdfs:label "immune response profile" ;
  rdfs:comment "Process profile that reflects a pattern of a specific immune response." ;
  rdfs:subClassOf obo:BFO_0000144 .

obo:VO_0007113 a rdfs:Class ;
  rdfs:label "TLR-9/GM vaccine" ;
  rdfs:comment "Gene name: Tyrosinase" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0000947 a rdfs:Class ;
  rdfs:label "PreveNile vaccine" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000752 .

obo:VO_0000372 a rdfs:Class ;
  rdfs:label "profertility vaccine" ;
  rdfs:comment "A vaccine that is used to improve conception." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0012405 a rdfs:Class ;
  rdfs:label "NucA" ;
  rdfs:comment "Mouse antiserum directed against the recombinant NucA protein was reactive on Western immunoblots and whole-cell ELISA with all H. influenzae strains tested including Eagan and was bactericidal for two heterologous strains tested. The antiserum also resulted in a log reduction in bacteremia, in an infant-rat protection study with H. influenzae type b as the challenge strain [PubMed: 10768940]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:VO_0000293 a rdfs:Class ;
  rdfs:label "pND2 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000282 a rdfs:Class ;
  rdfs:label "pMAMneoBlue DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0006022 a rdfs:Class ;
  rdfs:label "influenza nasal unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0000586 a rdfs:Class ;
  rdfs:label "multivalent vaccine against bacterial and viral diseases" ;
  rdfs:comment "a multivalent vaccine that is designed to immunize against at least one bacterial disease and one viral disease." ;
  rdfs:subClassOf obo:VO_0000556 , obo:VO_0000563 .

obo:VO_0000081 a rdfs:Class ;
  rdfs:label "influenza A (H1N1) 2009 Monovalent Vaccine (Novartis)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003211 , obo:VO_0010415 .

obo:VO_0000304 a rdfs:Class ;
  rdfs:label "pRK DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0017742 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0017738 , obo:VO_0017741 , obo:VO_0017771 .

obo:VO_0011474 a rdfs:Class ;
  rdfs:label "Newcastle disease virus vaccine by Dow AgroSciences" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001222 .

obo:VO_0002129 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus, Live Canarypox Vector Vaccine (USDA: 14W7.R0)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002401 , obo:VO_0007748 .

obo:VO_0018746 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Injectable Solution [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0018745 .

obo:VO_0020088 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003499 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0012174 a rdfs:Class ;
  rdfs:label "Chlamydophila psittaci vaccine" ;
  rdfs:comment "A Chlamydia bacterial vaccine against Chlamydophila psittaci infection" ;
  rdfs:subClassOf obo:VO_0000573 .

obo:VO_0000634 a rdfs:Class ;
  rdfs:label "intravenous vaccination" ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0001929 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002353 .

obo:VO_0010865 a rdfs:Class ;
  rdfs:label "Tbp2" ;
  rdfs:comment "Recombinant Tbp1 and Tbp2 proteins were expressed from Escherichia coli and antisera were raised to the purified proteins. In a passive model of bacteraemia, infant rats were protected from challenge with Hib after transfer of anti-rTbp2 antiserum, but not after anti-rTbp1 antiserum [PubMed: 8830248]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:VO_0000603 a rdfs:Class ;
  rdfs:label "BCG mutant secreting listeriolysin" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0019405 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Pentacel]" ;
  rdfs:subClassOf obo:VO_0000084 .

obo:VO_0018878 a rdfs:Class ;
  rdfs:label "influenza A virus A/Delaware/39/2019 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:VO_0020384 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0003855 , obo:VO_0020375 .

obo:VO_0020209 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0020498 .

obo:VO_0002896 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium IppA/IppB/msbB" ;
  rdfs:comment "An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" .

obo:VO_0016224 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Mevita" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:VO_0002855 a rdfs:Class ;
  rdfs:label "Francisella tularensis wbtI mutant vaccine" ;
  rdfs:comment "A wbtI mutant is attenuated in mice. The mutant protected against a low dose challenge with the parental strain, but was less effective against higher doses. However, increasing the immunization dose increased the resistance to higher challenge doses" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0018597 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 2210000 UNT" ;
  rdfs:subClassOf obo:VO_0004825 .

obo:VO_0001244 a rdfs:Class ;
  rdfs:label "Prevnar 13 vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000424 , obo:VO_0000556 .

obo:VO_0015271 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0015268 , obo:VO_0015274 .

obo:VO_0004747 a rdfs:Class ;
  rdfs:label "ALVAC-AI-H5 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0016647 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by ADL" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0015538 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution [Heptavax]" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0017285 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Tripacel] Box of 5" ;
  rdfs:subClassOf obo:VO_0017284 , obo:VO_0017286 .

obo:VO_0015133 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015300 .

obo:VO_0010817 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0017194 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017189 , obo:VO_0017201 , obo:VO_0017635 .

obo:VO_0018478 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 20 by Gerke" ;
  rdfs:subClassOf obo:VO_0018440 , obo:VO_0018459 .

obo:VO_0001699 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1651.05)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0016744 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] Box of 5" ;
  rdfs:subClassOf obo:VO_0016710 , obo:VO_0016772 .

obo:VO_0015152 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0003343 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0003093 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum RTS,S/AS01 vaccine" ;
  rdfs:comment "A malaria vaccine that consists of hepatitis B surface antigen virus-like particles, incorporating a portion of the Plasmodium falciparum-derived circumsporozoite protein and a liposome-based adjuvant." ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000455 , obo:VO_0010489 .

obo:VO_0010773 a rdfs:Class ;
  rdfs:label "Coxiella burnetii protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0018127 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Vaccine / Rubella virus / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0010735 , obo:VO_0018126 .

obo:VO_0004264 a rdfs:Class ;
  rdfs:label "rgp120 HIV vaccine with immunoliposomes" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0011367 a rdfs:Class ;
  rdfs:label "cancer DNA vaccine encoding Endoglin Boosted with recombinant Endoglin Protein" ;
  rdfs:comment "Gene name: Eng" ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0011294 a rdfs:Class ;
  rdfs:label "T. cruzi TS" ;
  rdfs:comment "To develop a vaccine strategy taking advantage of activated CD8(+)T cells,a DNA vaccine, designated pGFP-TSA1, encoding a fusion protein linking GFP to a single CTL epitope of TSA1(TS), a leading candidate for vaccine against T. cruzi was constructed. C57BL/6 mice vaccinated with this plasmid showed suppressed parasitemia and prolonged survival. Vaccination with pGFP-TSA1 enhanced epitope-specific cytotoxicity and IFN-gamma secretion by CD8(+)T cells [PubMed: 18321749]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:DOID_10283 a rdfs:Class ;
  rdfs:label "prostate cancer"@en ;
  rdfs:comment "A male reproductive organ cancer that is located_in the prostate."@en ;
  rdfs:subClassOf obo:DOID_3856 .

obo:VO_0018569 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Intramuscular Solution [Typherix] by GSK" ;
  rdfs:subClassOf obo:VO_0018568 .

obo:VO_0015952 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat] Box of 1" ;
  rdfs:subClassOf obo:VO_0015641 , obo:VO_0015726 , obo:VO_0016039 .

obo:VO_0019278 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Washington/19/2020 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017539 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution [Tetamun]" ;
  rdfs:subClassOf obo:VO_0017678 .

obo:VO_0003407 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0004311 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine H5 DNA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0003871 a rdfs:Class ;
  rdfs:label "COMVAX Injectable Product" ;
  rdfs:subClassOf obo:VO_0000028 .

obo:VO_0000722 a rdfs:Class ;
  rdfs:label "Brucella suis strain 2 vaccine" ;
  rdfs:comment "An orally administrable brucellosis vaccine that was was developed in China. It is effective for oral vaccination of sheep, goats, cattle and pigs." ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001136 .

obo:VO_0003639 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003638 .

obo:VO_0004442 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine hTRP2 encoding TRP-2" ;
  rdfs:comment "Gene name: gp100" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0000852 a rdfs:Class ;
  rdfs:label "Periovac vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000649 , obo:VO_0000865 .

obo:GO_0032991 a rdfs:Class ;
  rdfs:label "protein-containing complex" ;
  rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0010273 a rdfs:Class ;
  rdfs:label "host adverse event  to vaccine datum" ;
  rdfs:comment "A measurment datum that records the presence or abasence of adverse event in a host in response of some vaccine." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:NCBITaxon_197911 a rdfs:Class ;
  rdfs:label "Alphainfluenzavirus" ;
  rdfs:subClassOf obo:NCBITaxon_11308 .

obo:VO_0011550 a rdfs:Class ;
  rdfs:label "Giardia duodenalis DNA vaccine encoding CWP2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001083 .

obo:VO_0020886 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0020851 .

obo:VO_0015236 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML [Havrix]" ;
  rdfs:subClassOf obo:VO_0000052 , obo:VO_0015235 .

obo:VO_0016151 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 20 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015887 .

obo:VO_0020056 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Injectable Suspension [Afluria 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020298 .

obo:VO_0018706 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 TCID Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018702 .

obo:VO_0021175 a rdfs:Class ;
  rdfs:label "0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0020719 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 660000000 CFU Injection" ;
  rdfs:subClassOf obo:VO_0020717 , obo:VO_0020740 .

obo:VO_0005400 a rdfs:Class ;
  rdfs:label "Prime-2-CoV-Beta vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Speransa Therapeutics." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0010999 a rdfs:Class ;
  rdfs:label "SopB" ;
  rdfs:comment "The entire SopB and SifB genes were cloned into DNA vaccine vectors and were administered along with live attenuated Salmonella.  It was found that SopB vaccination reduced the bacterial burden of organs by about 5-fold on day 4 and day 8 after challenge with virulent Salmonella and proved to be a more efficient vaccination strategy than live attenuated bacteria alone [PubMed: 19428891]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010776 .

obo:VO_0004620 a rdfs:Class ;
  rdfs:label "vFP89-H5 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:NCBITaxon_260963 a rdfs:Class ;
  rdfs:label "Avulavirus" ;
  rdfs:subClassOf obo:NCBITaxon_2560069 .

obo:VO_0003967 a rdfs:Class ;
  rdfs:label "HEPLISAV-B 20 MCG per 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003966 .

obo:VO_0001013 a rdfs:Class ;
  rdfs:label "Morupar vaccine" ;
  rdfs:comment "A Measles-Mumps-Rubella vaccine that is manufactured by Sanofi Aventis." ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0000732 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus vaccine" ;
  rdfs:comment "A Corynebacterium diphtheriae vaccine that also protect against infection with Clostridium tetani." ;
  rdfs:subClassOf obo:VO_0000640 , obo:VO_0000735 .

obo:VO_0002521 a rdfs:Class ;
  rdfs:label "apxIIIB from Actinobacillus pleuropneumoniae" ;
  rdfs:comment "An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001384 .

obo:OPL_0000274 a rdfs:Class ;
  rdfs:label "Plasmodium ookinete" ;
  rdfs:comment "A Plasmodium that is a 'banana-shaped' form originates from the round zygote. The ookinete is found in the midgut of a mosquito vector and traverses the midgut wall of a mosquito vector." ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0003462 a rdfs:Class ;
  rdfs:label "Vaqta Injectable Product" ;
  rdfs:subClassOf obo:VO_0010745 .

obo:VO_0020341 a rdfs:Class ;
  rdfs:label "Flulaval Quad 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 , obo:VO_0010416 .

obo:VO_0003964 a rdfs:Class ;
  rdfs:label "obsolete vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML [Vaxchora]" .

obo:VO_0015523 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.001 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0017444 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.08 MG/ML Injection [ActHIB]" ;
  rdfs:subClassOf obo:VO_0017441 , obo:VO_0017443 .

obo:VO_0017365 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxin Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0003095 , obo:VO_0017364 .

obo:VO_0011189 a rdfs:Class ;
  rdfs:label "NcMAG1" ;
  rdfs:comment "Intraperitoneal application of NcMAG1 suspended in saponin adjuvants lead to protection against disease in 50% of animals vaccinated in a C57Bl/6 mouse cerebral infection model [PubMed: 19835644]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0002936 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica htrA mutant vaccine" ;
  rdfs:comment "A htrA mutant in Yersinia enterocolitica was attenuated and provided partial protection against challenge in mice" ;
  rdfs:subClassOf obo:VO_0012186 .

obo:VO_0000186 a rdfs:Class ;
  rdfs:label "RNA vaccine" ;
  rdfs:comment "A vaccine that uses RNA(s) derived from a pathogen organism." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:VO_0002776 a rdfs:Class ;
  rdfs:label "Listeria monocytogenes actA mutant vaccine" ;
  rdfs:comment "An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes" ;
  rdfs:subClassOf obo:VO_0002500 .

obo:VO_0004571 a rdfs:Class ;
  rdfs:label "Pseudomonas aeruginosa DNA vaccine pGACAG-PcrV" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000393 .

obo:VO_0019532 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.04 MG/ML Injection [Recombivax]" ;
  rdfs:subClassOf obo:VO_0015498 .

obo:VO_0010093 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA17" ;
  rdfs:comment "A GRA17 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0003679 a rdfs:Class ;
  rdfs:label "Fluvirin 2015-2016 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003676 .

obo:VO_0015923 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015632 , obo:VO_0015690 , obo:VO_0016026 .

obo:VO_0020689 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020677 .

obo:VO_0019934 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0010936 a rdfs:Class ;
  rdfs:label "Ag85A" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0015997 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015660 , obo:VO_0015783 .

obo:VO_0010346 a rdfs:Class ;
  rdfs:label "Fluzone Intradermal vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0007131 a rdfs:Class ;
  rdfs:label "Ovarian Cancer Peptide Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of synthetic peptides corresponding to naturally-occurring peptides derived from ovarian cancer cell antigens. Ovarian cancer peptide vaccine may elicit a cytotoxic T-cell response against tumor cells expressing the related ovarian cancer cell antigens." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0016997 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [T Immun] Box of 1" ;
  rdfs:subClassOf obo:VO_0016996 , obo:VO_0017019 , obo:VO_0017485 .

obo:VO_0016221 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015905 .

obo:VO_0017716 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017715 .

obo:VO_0020551 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluarix]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020858 .

obo:VO_0000361 a rdfs:Class ;
  rdfs:label "vaccine-induced leukocyte activation" ;
  rdfs:subClassOf obo:VO_0000180 .

obo:VO_0015198 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015197 .

obo:VO_0000121 a rdfs:Class ;
  rdfs:label "YF-Vax vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000714 , obo:VO_0003134 .

obo:VO_0005487 a rdfs:Class ;
  rdfs:label "leukemia cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against leukemia." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0004344 a rdfs:Class ;
  rdfs:label "HIV DNA vaccine SHIV-89.6 DNA (DNA/89.6)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0017208 a rdfs:Class ;
  rdfs:label "1 ML tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution [Tetabulin] Box of 1 by Baxter" ;
  rdfs:subClassOf obo:VO_0017207 .

obo:VO_0011334 a rdfs:Class ;
  rdfs:label "MAPP15" ;
  rdfs:comment "The microtubule-associate protein (MAP p15) was tested as a vaccine in mice, and tests showed that p15 (native or recombinant) generated up to 100% protection from an otherwise lethal challenge of a heterologous strain of Trypanosoma brucei [PubMed: 15161078]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010854 .

obo:VO_0019570 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone 2015-2016]" ;
  rdfs:subClassOf obo:VO_0010427 , obo:VO_0015080 , obo:VO_0019544 .

obo:VO_0017873 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0016560 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000745 , obo:VO_0001214 .

obo:VO_0004206 a rdfs:Class ;
  rdfs:label "BOOSTRIX vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0004205 .

obo:VO_0000980 a rdfs:Class ;
  rdfs:label "Flucelvax" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0001377 a rdfs:Class ;
  rdfs:label "unvaccinated" ;
  rdfs:comment "an organismal quality that indicates an organism (e.g., human) is unvaccinated with any vaccine." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:VO_0017791 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 15000000000 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017790 , obo:VO_0017799 .

obo:VO_0016261 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015921 .

obo:VO_0017756 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017770 , obo:VO_0017803 .

obo:VO_0016925 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.05 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017389 .

obo:VO_0019365 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen (isoform L), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform M), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform S), recombinant 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0019514 .

obo:VO_0018239 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 20000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018254 .

obo:VO_0003021 a rdfs:Class ;
  rdfs:label "oral vaccination" ;
  rdfs:comment "vaccination process that occurs in oral route." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0018296 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018285 .

obo:VO_0007544 a rdfs:Class ;
  rdfs:label "MVA-PSA/PAP Prostate Cancer Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the gene for the CD4 epitope-rich C-terminal domain of the Epstein Barr Virus (EBV) antigen EBNA1 and fused to the full-length of the EBV-associated antigen latent membrane protein 2 (LMP2), with potential immunostimulatory and antineoplastic activities. Upon administration, MVA EBNA1/LMP2 vaccine may elicit a cytotoxic T-cell immune response against cancer cells expressing EBNA1 and LMP2. Multi-antigen vaccine therapy may be more efficacious than single-antigen therapy vaccine therapy. EBNA1, a sequence-specific DNA binding protein, plays an important role in EBV episomal genome maintenance and gene transactivation." ;
  rdfs:subClassOf obo:VO_0005498 , obo:VO_0007657 .

obo:NCBITaxon_470137 a rdfs:Class ;
  rdfs:label "Brucella suis ATCC 23445" ;
  rdfs:subClassOf obo:NCBITaxon_29461 .

obo:VO_0018035 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injectable Solution [Ipol] Box of 10" ;
  rdfs:subClassOf obo:VO_0018034 , obo:VO_0018036 .

obo:VO_0003622 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003617 .

obo:VO_0016008 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015661 , obo:VO_0015795 .

obo:VO_0020359 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0003856 .

obo:VO_0019267 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/North Carolina/04/2016 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010431 .

obo:VO_0001299 a rdfs:Class ;
  rdfs:label "interleukin-7 vaccine adjuvant" ;
  rdfs:comment "A cytokine vaccine adjuvant that includes IL-7." ;
  rdfs:subClassOf obo:VO_0001353 .

obo:VO_0015187 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015180 .

obo:VO_0001417 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis gene" ;
  rdfs:comment "A bacterial gene that is from Neisseria meningitidis." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:OPL_0000386 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii merozoite" ;
  rdfs:comment "A Plasmodium yoelii in merozoite stage." ;
  rdfs:subClassOf obo:NCBITaxon_5861 , obo:OPL_0000270 .

obo:VO_0020939 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.009 MG/ML" ;
  rdfs:subClassOf obo:VO_0003507 , obo:VO_0004914 .

obo:VO_0020232 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain 100000000 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020239 , obo:VO_0020240 .

obo:VO_0015733 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 250" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015804 .

obo:VO_0001139 a rdfs:Class ;
  rdfs:label "vaccine organism viability" ;
  rdfs:comment "vaccine viability is a viability of a vaccine organism." ;
  rdfs:subClassOf obo:PATO_0000169 .

obo:VO_0010149 a rdfs:Class ;
  rdfs:label "no vaccine administered" ;
  rdfs:comment "An information content entity that specify no vaccine adminstered." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0020106 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine / L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine / L1 protein, human papillomavirus type 31 vaccine / L1 protein, human papillomavirus type 33 vaccine / L1 protein, human papillomavirus type 45 vaccine / L1 protein, human papillomavirus type 52 vaccine / L1 protein, human papillomavirus type 58 vaccine / L1 protein, human papillomavirus type 6 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 .

obo:VO_0017597 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0002602 a rdfs:Class ;
  rdfs:label "sodB from Francisella tularensis" ;
  rdfs:comment "C57BL/6 mice were vaccinated intranasally (i.n.) with the sodB(Ft) mutant and challenged i.n. with lethal doses of F. tularensis SchuS4. SodB(Ft) vaccinated mice following SchuS4 challenge exhibited significantly reduced bacterial burden in lungs, liver and spleen, regulated production of pro-inflammatory cytokines and less severe histopathological lesions compared to the LVS vaccinated mice. The sodB(Ft) vaccination induced a potent humoral immune response and protection against SchuS4 required both CD4 and CD8 T cells in the vaccinated mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0003522 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0003521 .

obo:VO_0017821 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 , obo:VO_0017813 .

obo:VO_0010806 a rdfs:Class ;
  rdfs:label "Feline leukemia virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0000883 a rdfs:Class ;
  rdfs:label "multi-dose Vaxigrip vaccine" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0000868 .

obo:VO_0003418 a rdfs:Class ;
  rdfs:label "Mumps-Rubella Vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000641 , obo:VO_0010442 , obo:VO_0010450 .

obo:VO_0011200 a rdfs:Class ;
  rdfs:label "NcMIC1" ;
  rdfs:comment "Study assessed the potential protectivity of NcMIC1-based vaccination against experimental N. caninum infection in mice.  Quantitative real-time PCR revealed that the infection intensity was significantly reduced in the group vaccinated with recNcMIC1 antigen.  Serological analysis showed that only recNcMIC1-immunized animals generated detectable antibody levels recognizing native NcMIC1. Thus, of all protocols applied, only recNcMIC1 vaccination appears to be suited to reduce cerebral infection in mice challenged with N. caninum tachyzoites [PubMed: 16108562]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0017240 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Hepatitis B Surface Antigen Vaccine / Human poliovirus / tetanus toxoid vaccine, inactivated Injectable Solution [Infanrix Hexa]" ;
  rdfs:subClassOf obo:VO_0017239 .

obo:VO_0016575 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Twinrix Paediatric]" ;
  rdfs:subClassOf obo:VO_0016580 .

obo:VO_0015603 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015557 .

obo:VO_0018190 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus vaccine / Varicella Virus Vaccine Live (Oka-Merck) strain Injectable Solution [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0018189 .

obo:VO_0005460 a rdfs:Class ;
  rdfs:label "DTP-Haemophilus influenzae type b conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000641 , obo:VO_0000738 .

obo:VO_0004162 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii DNA vaccine encoding PyHEP17 protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002514 .

obo:VO_0020206 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.2 MG/ML Injectable Suspension [Spikevax]" ;
  rdfs:subClassOf obo:VO_0020204 , obo:VO_0020205 .

obo:VO_0011034 a rdfs:Class ;
  rdfs:label "PtxA" ;
  rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model.  These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:VO_0001019 a rdfs:Class ;
  rdfs:label "live attenuated avian reovirus vaccine" ;
  rdfs:comment "an avian reovirus vaccine that using live attenauted reovirus. " ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0001513 .

obo:NCBITaxon_2946633 a rdfs:Class ;
  rdfs:label "Heptrevirinae" ;
  rdfs:subClassOf obo:NCBITaxon_12058 .

obo:VO_0004324 a rdfs:Class ;
  rdfs:label "Newcastle disease virus DNA vaccine pCAGF encoding the F protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001222 .

obo:VO_0003797 a rdfs:Class ;
  rdfs:label "Shingrix Injectable Product" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003317 .

obo:VO_0017427 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 50 LFU/ML / tetanus toxin 10 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017370 .

obo:VO_0007713 a rdfs:Class ;
  rdfs:label "NY-ESO-1/PRAME/MAGE-A3/WT-1 peptide vaccine" ;
  rdfs:comment "A cancer vaccine comprised of synthetic peptides derived from the cancer-testis antigen NY-ESO-1, preferentially expressed antigen in melanoma (PRAME), human melanoma antigen A3 (MAGE-A3) and the human Wilms tumor protein-1 (WT-1), with potential immunostimulating and antineoplastic activities. NY-ESO-1/PRAME/MAGE-A3/WT-1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing NY-ESO-1, PRAME, MAGE-A3 and WT-1, resulting in tumor cell lysis. As proteins are degraded in cells, peptides are presented on the surface of these cells as a complex with tissue type molecules (HLA molecules). T-cells may then recognize the peptide-HLA complexes, via its T-cell receptor, potentially resulting in tumor-cell killing, if sufficient priming takes place. Cancer testis antigens (CTA's) are known to be immunogenic and are only expressed at immunoprivileged sites, thus out of reach of immune responses, and on cancer cells, making them ideal targets for therapeutic cancer vaccination. The CTA's chosen were NY-ESO-1, MAGE-A3 and PRAME. WT-1 is additionally included as this protein has proven to be an important antigen in hematological malignancies. It is combined with azacitidine for treatment of patients with high-risk myelodysplastic syndrome or acute myeloid leukemia. " ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0010114 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii PLP1" ;
  rdfs:comment "A PLP1 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0004640 a rdfs:Class ;
  rdfs:label "E. coli-CPPs Edwardsiella tarda vaccine" ;
  rdfs:subClassOf obo:VO_0002506 .

obo:NCBITaxon_139 a rdfs:Class ;
  rdfs:label "Borreliella burgdorferi" ;
  rdfs:subClassOf obo:NCBITaxon_64895 .

obo:VO_0020065 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Afluria 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020298 .

obo:VO_0018358 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003340 .

obo:VO_0018517 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018524 .

obo:OBI_0000718 a rdfs:Class ;
  rdfs:label "pathogen role" ;
  rdfs:comment "pathogen role is a role which inheres in an organism and realized in the process of disease course in the organism bearing host role caused by the organism bearing pathogen role"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0017129 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0011543 a rdfs:Class ;
  rdfs:label "Sin Nombre virus DNA vaccine encoding SNVsSgp1 (NP)" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012167 .

obo:VO_0021023 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003275 , obo:VO_0021040 .

obo:VO_0007067 a rdfs:Class ;
  rdfs:label "RASVAC-C Vaccine" ;
  rdfs:comment "A synthetic vaccine used for cancer immunotherapy also known as Ras(cis 12)-Vaccinia Vaccine, RASVAC-C is based on a mutant peptide epitope of the Ras oncoprotein at codon 12 that induces recognition and induction of tumor-specific, cell-mediated immune responses. Ras is an intracellular GTP-binding protein involved in signal transduction and regulation of proliferation and differentiation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0020029 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe [Afluria 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020028 , obo:VO_0020298 .

obo:VO_0007164 a rdfs:Class ;
  rdfs:label "Recombinant Vaccinia-Prostate Specific Antigen Vaccine" ;
  rdfs:comment "A recombinant vaccinia virus encoding prostate-specific antigen (PSA). Vaccination with recombinant vaccinia-PSA may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for PSA, which may decrease tumor growth." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0010244 a rdfs:Class ;
  rdfs:label "assay analysis tool version variable" ;
  rdfs:comment "A variable representing the programs used to analyze an assay" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0006055 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent booster preservative free 10 mcg/0.2 mL dose tris-sucrose formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0004694 a rdfs:Class ;
  rdfs:label "RCN-IRES-tPA-YpF1 Yersinia pestis vaccine" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0006078 a rdfs:Class ;
  rdfs:label "Tick-borne encephalitis vaccine (non-US)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000952 .

obo:VO_0001764 a rdfs:Class ;
  rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0000712 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0005809 a rdfs:Class ;
  rdfs:label "RH-AMA1KO vaccine" ;
  rdfs:comment "A Live attenuated vaccine RH-AMA1KO that immunizes against Toxoplasma gondii trypmastigote." ;
  rdfs:subClassOf obo:VO_0000994 .

obo:VO_0018542 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection [Cervarix] Box of 20" ;
  rdfs:subClassOf obo:VO_0018540 , obo:VO_0018544 .

obo:VO_0020928 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 50000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003502 , obo:VO_0004914 .

obo:VO_0020762 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG Injectable Solution [OncoTICE] Box of 1" ;
  rdfs:subClassOf obo:VO_0020761 , obo:VO_0020765 .

obo:VO_0016889 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0016881 .

obo:VO_0004079 a rdfs:Class ;
  rdfs:label "V-LSN vaccine" ;
  rdfs:subClassOf obo:VO_0012177 .

obo:VO_0002453 a rdfs:Class ;
  rdfs:label "Newcastle Disease-Bronchitis Vaccine-Salmonella Enteritidis Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0000768 , obo:VO_0002457 .

obo:VO_0016127 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 50 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015880 .

obo:VO_0018413 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 6B vaccine 0.001 MG" ;
  rdfs:subClassOf obo:VO_0003250 .

obo:VO_0016672 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML [Diphtherie-Adsorbat-Impfstoff Behring]" ;
  rdfs:subClassOf obo:VO_0003429 .

obo:VO_0017846 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine Injectable Suspension [Trumenba]" ;
  rdfs:subClassOf obo:VO_0003081 , obo:VO_0017895 .

obo:VO_0018919 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0020325 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2020-2021 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003067 , obo:VO_0010424 .

obo:VO_0007332 a rdfs:Class ;
  rdfs:label "Brain Tumor Initiating Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine comprised of brain tumor initiating cells (BTICs), with potential immunostimulating and antineoplastic activity. BITCs are from the glioblastoma multiforme (GBM) cell line GBM-6 and contain glioma stem-like cell-associated antigens. Upon administration, the BITC vaccine may stimulate a specific anti-tumoral cytotoxic T-lymphocyte (CTL) response against brain tumor cancer cells and brain tumor stem like cells, resulting in tumor cell lysis. BITC have unique antigenicity and have the ability to self-renew; vaccination against BITC antigens may kill these cells and may prevent tumor recurrences." ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0007106 a rdfs:Class ;
  rdfs:label "recombinant Vaccinia-TRP1 vaccine" ;
  rdfs:comment "A recombinant vaccinia virus encoding the melanocyte differentiation antigen tyrosinase-related protein-1 (TRP-1) with potential use in cancer immunotherapy." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0017780 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017778 , obo:VO_0017779 , obo:VO_0017801 .

obo:VO_0000802 a rdfs:Class ;
  rdfs:label "vaccine storage in refrigerator" ;
  rdfs:comment "vaccine storage that is executed in refrigerator, usually 0-10^C." ;
  rdfs:subClassOf obo:VO_0000800 .

obo:VO_0010716 a rdfs:Class ;
  rdfs:label "Imovax Polio vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010447 .

obo:VO_0010121 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii SAG5C" ;
  rdfs:comment "A SAG5C protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0007438 a rdfs:Class ;
  rdfs:label "IL-12-expressing Mesenchymal Stem Cell Vaccine GX-051" ;
  rdfs:comment "Human mesenchymal stem cells (MSCs) transduced with a retroviral vector encoding a modified form of the cytokine interleukin-12 (IL-12), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration, IL-12-expressing MSC vaccine GX-051 secretes IL-12. IL-12 activates the immune system by both promoting the secretion of interferon-gamma, which activates natural killer cells (NKs), and inducing cytotoxic T-cell responses, which may result in both decreased cell proliferation and increased cell death in tumor cells." ;
  rdfs:subClassOf obo:VO_0005497 , obo:VO_0007657 .

obo:VO_0011193 a rdfs:Class ;
  rdfs:label "ClpP" ;
  rdfs:comment "The protective effects of ATP-dependent caseinolytic protease (ClpP) was evaluated. Vaccinated mice were intraperitoneally and/or intranasally challenged with different pneumococcal strains. In intraperitoneal challenge models with pneumococcal strain D39 (serotype 2), clpP elicited some protection in mice [PubMed: 20038538]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0001780 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis Killed Virus Vaccine (USDA: 1525.22)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001486 , obo:VO_0007748 .

obo:VO_0015964 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015732 , obo:VO_0015738 , obo:VO_0016048 .

obo:VO_0004900 a rdfs:Class ;
  rdfs:label "MERS vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0004897 .

obo:VO_0002109 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Canarypox Vector Vaccine (USDA: 13D1.R1)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0000960 a rdfs:Class ;
  rdfs:label "killed infectious bursal disease virus vaccine" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0001497 .

obo:VO_0006015 a rdfs:Class ;
  rdfs:label "hepatitis B vaccine unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010439 .

obo:VO_0017219 a rdfs:Class ;
  rdfs:label "7.5 ML tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017471 .

obo:VO_0001749 a rdfs:Class ;
  rdfs:label "Distemper Modified Live Virus Vaccine (USDA: 1471.10)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012178 .

obo:VO_0017976 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.03 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017953 .

obo:VO_0017579 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0017555 .

obo:VO_0020394 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0020377 , obo:VO_0020398 .

obo:VO_0011178 a rdfs:Class ;
  rdfs:label "TM-1" ;
  rdfs:comment "An antiserum raised in chicken against the TM-1 polypeptide, which was produced by recombinant Escherichia coli cells and purified by column chromatography, inhibited growth of M.g. cells in vitro. Moreover, chickens immunized with this 29 kDa polypeptide (TM-1) were partially protected from a challenge with virulent M.g [PubMed: 8212828]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010819 .

obo:VO_0002947 a rdfs:Class ;
  rdfs:label "Yersinia pseudotuberculosis phoP mutant vaccine" ;
  rdfs:comment "A phoP mutant in Yersinia pseudotuberculosis (Yptb) was attenuated and provided protection against oral challenge with virulent Yptb in mice" ;
  rdfs:subClassOf obo:VO_0002510 .

obo:VO_0017406 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 4 LFU/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0017405 .

obo:VO_0015784 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015596 .

obo:VO_0017862 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.5 MG" ;
  rdfs:subClassOf obo:VO_0004860 .

obo:VO_0002820 a rdfs:Class ;
  rdfs:label "Brucella melitensis WR201 (16MΔpurEK) vaccine" ;
  rdfs:comment "Mice infected with delta purE201 developed only five to eight times normal spleen weight at 1 week p.i. and produced no interleukin-6 in their serum, which is much lower than the mice infected with the parental strain (16M)" ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0011248 a rdfs:Class ;
  rdfs:label "Gp50" ;
  rdfs:comment "A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 was administered to pigs to determine if it would have a greater protective effect than a vector containing the gene for gp50 alone. Both NYVAC vectors protected pigs similarly from virulent pseudorabies virus challenge [PubMed: 8904669]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010800 .

obo:VO_0002990 a rdfs:Class ;
  rdfs:label "Pseudorabies virus US3 mutant vaccine" ;
  rdfs:comment "Researchers intranasally inoculated pigs, the natural host of this virus, with mutant PRV strains in which the genes encoding the protein kinase (US3) proteins were inactivated. After challenge infection with the virulent PRV strain NIA-3, no virus was excreted by wt PRV- and PK- mutant-immunized animals, indicating complete protective immunity" ;
  rdfs:subClassOf obo:VO_0000750 .

obo:VO_0020492 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2021 Southern Hemisphere vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010425 .

obo:VO_0017236 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella Pertussis Filamentous Haemagglutinin Antigen / diphtheria toxoid vaccine, inactivated / pertactin adsorbed / tetanus toxoid vaccine, inactivated Injection [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0017234 .

obo:VO_0021158 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0004174 a rdfs:Class ;
  rdfs:label "BacHA derived from Influenza A virus (A/Indonesia/CDC669/2006(H5N1)) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0007489 a rdfs:Class ;
  rdfs:label "gp100/IFA vaccine" ;
  rdfs:comment """To understand why cancer vaccine-induced T cells often do not eradicate tumors, we studied immune responses in mice vaccinated with gp100 melanoma peptide in incomplete Freund's adjuvant (peptide/IFA), which is commonly used in clinical cancer vaccine trials (Hailemichael et al., 2013).
Immunization Route: Intramuscular injection (i.m.)""" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020678 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain Injectable Suspension [IMMUGRIP]" ;
  rdfs:subClassOf obo:VO_0020677 .

obo:VO_0012357 a rdfs:Class ;
  rdfs:label "Streptococcus pyogenes protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:VO_0012407 a rdfs:Class ;
  rdfs:label "PstS1" ;
  rdfs:comment "Vaccination with the recombinant PstS-1 antigen and cholera toxin significantly protected against the challenge given 10 days later, but only marginally after 12 weeks [PubMed: 10869767]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0011297 a rdfs:Class ;
  rdfs:label "T. cruzi CRP-10" ;
  rdfs:comment "A complement regulatory protein (CRP) of Trypanosoma cruzi was evaluated as a vaccine candidate in a murine model of experimental T. cruzi infection. Recombinant CRP derived from an Escherichia coli expression system and a plasmid encoding the full-length crp structural gene under the control of a eukaryotic promoter were used to immunize BALB/c mice. Immunization with both protein and DNA vaccines resulted in a Th1-type T-cell response, comparable antibody titers, and similar immunoglobulin G isotype profiles. Only mice immunized with the crp DNA plasmid produced antibodies capable of lysing the parasites in the presence of complement and were protected against a lethal challenge with T. cruzi trypomastigotes [PubMed: 10948115]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0017812 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y" ;
  rdfs:subClassOf obo:VO_0000053 .

obo:VO_0015122 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015286 .

obo:VO_0011209 a rdfs:Class ;
  rdfs:label "HN hemagglutinin-neuraminidase" ;
  rdfs:comment "Recombinant baculoviruses containing the fusion (F) and hemagglutinin-neuraminidase (HN) glycoprotein gene of the viscerotropic velogenic (vv) Newcastle disease virus (NDV) isolate, Kr-005/00, and a lentogenic La Sota strain of the NDV were constructed.  A single dose of rNDHN(V) had a protective effect against mortality (p <0.01) in chickens [PubMed: 18716451]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010805 .

obo:VO_0001723 a rdfs:Class ;
  rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000620 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0007186 a rdfs:Class ;
  rdfs:label "1(SOCS1)-silenced dendritic cell vaccine" ;
  rdfs:comment "To obtain SOCS1-silenced DCs, DCs derived from mouse bone marrow cells ex vivo were induced to differentiation in the presence of granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-4, and then transduced with Len-SOCS1-shRNA or control Len-GFP lentiviruses. The SOCS1-silenced DCs were loaded by TRP2 peptide to prepare the DC vaccine, which was induced to mature by LPS. The DCs were analyzed by flow cytometry (FCM) for surface expressions of MHCII and CD86 and by real-time PCR for the expressions of SOCS1, IL-10 as well as IL-12p40. B16 or IL-10-silenced B16 (IL-10(-/-);) cells were inoculated into C57BL/6 mice." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0018166 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018164 , obo:VO_0018179 .

obo:VO_0004025 a rdfs:Class ;
  rdfs:label "Treponema pallidum TmpB protein vaccine" ;
  rdfs:subClassOf obo:VO_0001230 .

obo:VO_0001685 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotype 1, Live Virus Vaccine (USDA: 16L1.09)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0001567 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001501 .

obo:VO_0017557 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0017556 , obo:VO_0017576 .

obo:VO_0001598 a rdfs:Class ;
  rdfs:label "avian influenza H7N3 Subtype, Killed Virus Vaccine (USDA: 10F5.13)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0001700 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 16G1.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0002510 a rdfs:Class ;
  rdfs:label "Yersinia pseudotuberculosis vaccine" ;
  rdfs:comment "A bacterial vaccine that protects against infections by Yersinia pseudotuberculosis." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000601 .

obo:VO_0017521 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017519 .

obo:VO_0017021 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0016995 , obo:VO_0017498 .

obo:VO_0000610 a rdfs:Class ;
  rdfs:label "viral vaccine vector" ;
  rdfs:comment "a vaccine vector that uses a virus as the vector." ;
  rdfs:subClassOf obo:VO_0000599 .

obo:VO_0007276 a rdfs:Class ;
  rdfs:label "autologous anti-gp100:154-162 T-cell receptor gene-engineered peripheral blood lymphocytes vaccine" ;
  rdfs:comment "Human autologous peripheral blood lymphocytes (PBLs) transduced with a glycoprotein 100 (gp100) epitope-determined T cell receptor (TCR) gene, with potential antineoplastic activity. PBLs are isolated from a melanoma patient and pulsed with a viral vector encoding the TCR specific for amino acid residues 154-162 of gp100 (KTWGQYWQV). After expansion ex vivo, the transduced autologous PBLs, expressing this specific TCR, are reintroduced into the patient and bind to melanoma cells expressing the gp100 protein, which may result in specific cytotoxic T-lymphocyte (CTL) killing of gp100-expressing melanoma cells. gp100 is a melanocyte lineage-specific antigen overexpressed in melanomas." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0017954 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0017933 .

obo:VO_0020125 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML / meningococcal polysaccharide vaccine group W-135 0.1 MG/ML / meningococcal polysaccharide vaccine group Y 0.1 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017819 .

obo:VO_0017772 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017770 .

obo:VO_0010194 a rdfs:Class ;
  rdfs:label "influenza, seasonal, Southern Hemisphere, quadrivalent, 0.5mL dose, no preservative" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0002161 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.12)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:OBI_0000245 a rdfs:Class ;
  rdfs:label "organization"@en ;
  rdfs:comment "An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0019398 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injectable Suspension [Pediarix]" ;
  rdfs:subClassOf obo:VO_0000082 , obo:VO_0019397 .

obo:VO_0018285 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003863 , obo:VO_0018272 .

obo:VO_0002233 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002487 , obo:VO_0007748 .

obo:VO_0017554 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0017548 .

obo:VO_0007207 a rdfs:Class ;
  rdfs:label "Adenovirus RSV-TK vaccine" ;
  rdfs:comment "A gene viral vector complex comprised of a replication-defective adenovirus and a herpes simplex virus thymidine kinase gene that activates ganciclovir, causing inhibition of DNA synthesis and apoptosis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0016413 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 25 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015958 , obo:VO_0015964 .

obo:VO_0004118 a rdfs:Class ;
  rdfs:label "Adenovirus vectors expressing Marburg virus glycoprotein vaccine" ;
  rdfs:subClassOf obo:VO_0012163 .

obo:VO_0017455 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis polysaccharide group Y tetanus toxoid conjugate" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0020478 a rdfs:Class ;
  rdfs:label "Fluzone 2010-2011 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 , obo:VO_0010426 .

obo:VO_0010301 a rdfs:Class ;
  rdfs:label "influenza B virus antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003519 .

obo:VO_0018528 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018620 .

obo:VO_0011503 a rdfs:Class ;
  rdfs:label "Yersinia enterocolititica Subunit V Antigen Protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012186 .

obo:VO_0004844 a rdfs:Class ;
  rdfs:label "Menveo Injectable Product" ;
  rdfs:subClassOf obo:VO_0001246 , obo:VO_0010445 .

obo:OPL_0000010 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum microgametocyte stage" ;
  rdfs:comment "A microgametocyte stage in the Plasmodium falciparum lifecycle that occurs either in the bloodstream of a human host or the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000143 , obo:OPL_0000192 , obo:OPL_0000291 .

obo:VO_0019696 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003715 , obo:VO_0010427 , obo:VO_0019695 .

obo:VO_0021153 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 0.05 MG/ML Prefilled Syringe [Bexsero]" ;
  rdfs:subClassOf obo:VO_0003066 .

obo:VO_0002794 a rdfs:Class ;
  rdfs:label "obsolete M. tuberculosis secA2 mutant" ;
  rdfs:comment "Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Guerin vaccination." .

obo:VO_0007191 a rdfs:Class ;
  rdfs:label "27-35(27L):MART-1 peptide vaccine" ;
  rdfs:comment "A synthetic peptide consisting of amino acids 27 through 35 of the melanoma differentiation antigen MART-1. 27-35(27L) MART-1 has a leucine substitution at amino acid position 27 to improve binding to HLA-A*0201. Vaccination with this agent may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against melanoma cells expressing MART-1." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0020695 a rdfs:Class ;
  rdfs:label "Antigens Surface Of Virus Influenza, strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain A / Switzerland / 9715293/2013, Nib-88 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0020694 .

obo:VO_0000041 a rdfs:Class ;
  rdfs:label "Escherichia coli vaccine" ;
  rdfs:comment "A bacterial vaccine that prevents against Escherichia coli infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003552 .

obo:VO_0000823 a rdfs:Class ;
  rdfs:label "Vibrio anguillarum vaccine" ;
  rdfs:comment "a bacterial vaccine against V. anguillarum infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000566 .

obo:VO_0000385 a rdfs:Class ;
  rdfs:label "Brucella abortus DNA vaccine encoding L7/L12 and P39" ;
  rdfs:subClassOf obo:VO_0001225 .

obo:VO_0017140 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 80" ;
  rdfs:subClassOf obo:VO_0017133 , obo:VO_0017151 , obo:VO_0017602 .

obo:VO_0010418 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2012-2013" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0019490 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.005 MG/ML / meningococcal group C polysaccharide 0.01 MG/ML / meningococcal polysaccharide vaccine group Y 0.01 MG/ML Injection [MenHibrix]" ;
  rdfs:subClassOf obo:VO_0000031 , obo:VO_0019489 .

obo:VO_0007072 a rdfs:Class ;
  rdfs:label "p.DOM-WT1-126 DNA Vaccine" ;
  rdfs:comment "A fusion DNA vaccine containing the first domain of fragment C (FrC) of tetanus toxin (TT865-1120) (p.DOM) fused to the human Wilms' Tumor gene-1 (WT1)-derived MHC class I-binding epitope WT1.126, with potential antitumor activity. Upon vaccination with p.DOM-WT1-126 DNA and subsequent electroporation, this vaccine may induce a WT1 epitope-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing cancer cells. WT1, a tumor associated antigen, is overexpressed in most types of leukemia and in a variety of solid cancers. The FrC of tetanus toxin contains the MHC II-binding sequence, p30, which induces T-helper cell activation for long-lasting immunity." ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0010982 a rdfs:Class ;
  rdfs:label "GNA2091" ;
  rdfs:comment "Protective antigen as shown in some assays [PubMed: 16825336]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0005032 a rdfs:Class ;
  rdfs:label "pCAT DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCAT.  This plasmid is 4364 base pairs in length and contains an ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019169 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 4 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0019462 .

obo:VO_0010925 a rdfs:Class ;
  rdfs:label "MOMP from C. psittaci" ;
  rdfs:comment "Plasmid DNA (pcDNA1::MOMP A) expressing the major outer membrane protein (MOMP) of Chlamydophila psittaci genotype A strain 89/1051 has been tested for its ability to induce protective immunity against Cp. psittaci challenge in budgerigars.  DNA immunisation significantly reduced clinical signs, macroscopic lesions, pharyngeal and cloacal excretion as well as chlamydial replication, even in the presence of pre-existing serum antibodies, as compared to the placebo-vaccinated controls [PubMed: 19640395]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010839 .

obo:VO_0001709 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, C2 Strain, Live VirusVaccine (USDA: 17B1.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0010013 a rdfs:Class ;
  rdfs:label "Leishmania  donovani Acen1" ;
  rdfs:comment "A Acen1 protein that is part of Leishmania  donovani" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0020696 a rdfs:Class ;
  rdfs:label "Antigens Surface Of Virus Influenza, strain B / Brisbane / 9/2014 Wild Type" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010308 , obo:VO_0010415 .

obo:VO_0018203 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0017354 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Hib Dpt Merieux]" ;
  rdfs:subClassOf obo:VO_0017349 .

obo:VO_0004495 a rdfs:Class ;
  rdfs:label "IHNV DNA vaccine pIHN-G encoding glycoproteins" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012165 .

obo:VO_0003376 a rdfs:Class ;
  rdfs:label "Stamaril Injectable Product" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003139 .

obo:VO_0007247 a rdfs:Class ;
  rdfs:label "ALVAC-MART-1 vaccine" ;
  rdfs:comment "A cancer vaccine containing a replication-defective recombinant canarypox virus (ALVAC), encoding an epitope of MART-1 (melanoma antigen recognized by T-cells), with potential immunostimulatory and antineoplastic activities. Upon administration, the MART-1 epitope is expressed by the ALVAC vector in ALVAC-MART-1 vaccine; a host cytotoxic T lymphocyte (CTL) response against MART-1-expressing tumor cells may follow, resulting in tumor cell lysis and decreased tumor cell proliferation" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0001237 a rdfs:Class ;
  rdfs:label "CpG DNA vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant compsed of CpG DNA." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0002680 a rdfs:Class ;
  rdfs:label "senB from Shigella" ;
  rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000169 .

obo:VO_0003736 a rdfs:Class ;
  rdfs:label "afluria 2018-2019 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003734 .

obo:VO_0020301 a rdfs:Class ;
  rdfs:label "Afluria 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000006 , obo:VO_0000578 , obo:VO_0010416 .

obo:VO_0017857 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide 2.5 MG" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010290 , obo:VO_0010444 .

obo:VO_0004811 a rdfs:Class ;
  rdfs:label "Recombinant Aeromonas hydrophila vaccine (Aera)" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0002505 .

obo:VO_0020157 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0017673 .

obo:VO_0021124 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0020304 .

obo:VO_0010735 a rdfs:Class ;
  rdfs:label "Priorix-Tetra vaccine" ;
  rdfs:comment "A Measles-Mumps-Rubella-Vericella vaccine that is live attenuated and manufactured by GlaxoSmithKline Biologicals. " ;
  rdfs:subClassOf obo:VO_0000714 , obo:VO_0000737 .

obo:VO_0011420 a rdfs:Class ;
  rdfs:label "Herpes simplex virus type 2 vaccine using phage displaying GG protein" ;
  rdfs:subClassOf obo:VO_0012168 .

obo:VO_0002440 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calicivirus vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001465 , obo:VO_0001487 , obo:VO_0001509 .

obo:VO_0016812 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Infanrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0016730 , obo:VO_0016754 , obo:VO_0016830 .

obo:VO_0018654 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection [Cervarix]" ;
  rdfs:subClassOf obo:VO_0018652 , obo:VO_0018653 .

obo:VO_0021106 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0020323 .

obo:VO_0021170 a rdfs:Class ;
  rdfs:label "0.3 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (XBB.1.5) 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:DOID_6536 a rdfs:Class ;
  rdfs:label "plasma cell neoplasm"@en ;
  rdfs:comment "A mature B-cell neoplasm that is composed of plasma cells."@en ;
  rdfs:subClassOf obo:DOID_707 .

obo:VO_0017921 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injection [ACWY Vax]" ;
  rdfs:subClassOf obo:VO_0003138 , obo:VO_0017820 .

obo:VO_0010898 a rdfs:Class ;
  rdfs:label "E0" ;
  rdfs:comment "Swine vaccinated with VVR expressing E0 and/or E2 resisted a lethal challenge infection with CSFV. Glycoprotein E0 represents a second determinant for the induction of protective immunity against classical swine fever [PubMed: 7666549]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010801 .

obo:VO_0021094 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010447 .

obo:VO_0017188 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0017631 .

obo:VO_0020217 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.05 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020215 .

obo:VO_0017048 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 50" ;
  rdfs:subClassOf obo:VO_0017031 , obo:VO_0017517 .

obo:VO_0002200 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1B82.50)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0017673 a rdfs:Class ;
  rdfs:label "Meningococcal-Tetanus Vaccine" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0003396 .

obo:VO_0000528 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis arabinomannan-protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000077 , obo:VO_0000195 .

obo:NCBITaxon_3052223 a rdfs:Class ;
  rdfs:label "Henipavirus hendraense" ;
  rdfs:subClassOf obo:NCBITaxon_260964 .

obo:VO_0017594 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML [Tetasorbat]" ;
  rdfs:subClassOf obo:VO_0017682 .

obo:VO_0019350 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020263 .

obo:VO_0016540 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:VO_0004411 a rdfs:Class ;
  rdfs:label "Herpes simplex virus DNA vaccine pSIN-gB encoding gB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0007626 a rdfs:Class ;
  rdfs:label "ipilimumab vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0003908 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010317 , obo:VO_0010415 .

obo:VO_0020616 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix]" ;
  rdfs:subClassOf obo:VO_0021035 .

obo:VO_0015303 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 10" ;
  rdfs:subClassOf obo:VO_0015301 , obo:VO_0015305 .

obo:VO_0001331 a rdfs:Class ;
  rdfs:label "Flagellin vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant composed of flagellin from gram-negative bacteria." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0019714 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0001187 a rdfs:Class ;
  rdfs:label "intramuscular vaccination" ;
  rdfs:comment "a vaccination that occurs in the intramuscular route." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0019352 a rdfs:Class ;
  rdfs:label "0.5 ML varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0020283 .

obo:VO_0016806 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 20" ;
  rdfs:subClassOf obo:VO_0016727 , obo:VO_0016748 , obo:VO_0016821 .

obo:VO_0017417 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0015591 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015528 , obo:VO_0015601 .

obo:VO_0000004 a rdfs:Class ;
  rdfs:label "ActHIB vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000662 , obo:VO_0000714 , obo:VO_0010437 .

obo:VO_0004307 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine A/NP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0000409 a rdfs:Class ;
  rdfs:label "licensed horse vaccine" ;
  rdfs:subClassOf obo:VO_0000363 , obo:VO_0001472 .

obo:VO_0007351 a rdfs:Class ;
  rdfs:label "Carcinoembryonic Antigen Peptide 1-6D Vaccine" ;
  rdfs:comment "9-residue human leukocyte antigen (HLA)-restricted fragment of carcinoembryonic antigen (CEA). Vaccination with carcinoembryonic antigen peptide 1-6D, which has the amino acid sequence YLSGANLNL, may elicit a cytotoxic T lymphocyte (CTL) immune response against tumors expressing CEA." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005430 , obo:VO_0007657 .

obo:VO_0004759 a rdfs:Class ;
  rdfs:label "rMVTT-HA-QH (H5N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0004568 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine M2-DNA/M2-Ad" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0020336 a rdfs:Class ;
  rdfs:label "FluLaval 2010-2011 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000043 , obo:VO_0010426 .

obo:VO_0020703 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020701 , obo:VO_0020702 , obo:VO_0020736 .

obo:OPL_0000338 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii tachyzoite" ;
  rdfs:comment "A Toxoplasma gondii that is formed in tissue in  a host and replicates quickly. This replaces the previous term as ." ;
  rdfs:subClassOf obo:NCBITaxon_5811 .

obo:VO_0000581 a rdfs:Class ;
  rdfs:label "H. influenzae gene" ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:NCBITaxon_206351 a rdfs:Class ;
  rdfs:label "Neisseriales" ;
  rdfs:subClassOf obo:NCBITaxon_28216 .

obo:VO_0017543 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0017678 .

obo:VO_0000920 a rdfs:Class ;
  rdfs:label "bovine albumin cell culture residual in vaccine" ;
  rdfs:comment "a cell culture residual in vaccine that is bovine albumin." ;
  rdfs:subClassOf obo:VO_0000856 .

obo:VO_0011227 a rdfs:Class ;
  rdfs:label "VP4 from Bovine rotavirus" ;
  rdfs:comment "Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system.  Challenge of neonates born to animals immunized with VP4 protein on assembled particles or in cell lysates showed protection against challenge with both homologous (bovine C486) and heterologous (SA-11) strains of rotavirus [PubMed: 8382422]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010789 .

obo:VO_0001851 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16F1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002435 , obo:VO_0007748 .

obo:VO_0000768 a rdfs:Class ;
  rdfs:label "Salmonella vaccine" ;
  rdfs:comment "Vaccine that protects against Salmonella species infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003552 .

obo:VO_0018094 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Prefilled Syringe [Priorix]" ;
  rdfs:subClassOf obo:VO_0018093 , obo:VO_0018229 .

obo:VO_0001051 a rdfs:Class ;
  rdfs:label "porcine adenovirus 3 vaccine vector" ;
  rdfs:comment "an adenovirus vaccine vector that uses a porcine adenovirus 3 strain" ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0020615 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0021034 .

obo:OPL_0000165 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Plasmodium falciparum." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0002993 a rdfs:Class ;
  rdfs:label "SARS-CoV E gene mutant vaccine" ;
  rdfs:comment "An E mutant is attenuated in hamsters and induces significant protection from challenge with wild type SARS" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0020991 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigens, strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain Nib-88 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0020988 .

obo:VO_0018558 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018557 .

obo:VO_0005339 a rdfs:Class ;
  rdfs:label "Ad5-triCoV/Mac vaccine" ;
  rdfs:comment "A SARS-CoV-2 replication deficient human adenovirus vector vaccine expressing the spike, nucleocapsid and RNA polymerase proteins." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:VO_0011012 a rdfs:Class ;
  rdfs:label "YPO0420" ;
  rdfs:comment "Using a mouse plague model, YPO0420 may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0007566 a rdfs:Class ;
  rdfs:label "G250 Peptide Vaccine" ;
  rdfs:comment "A naturally occurring 9-residue peptide of fibroblast growth factor 5 (FGF-5). Recognized by tumor infiltrating cytotoxic T lymphocytes originally isolated from a renal cell carcinoma that overexpressed FGF-5, FGF-5:172-176/217-220 peptide activates various cytotoxic CD8 lymphocytes in an HLA-restricted manner. Overexpressed in several cancer cell lines, FGF-5 is a tumor-associated antigen that may be useful in cancer immunotherapy." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0018155 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0018143 .

obo:VO_0017662 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Tetanus-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0007410 a rdfs:Class ;
  rdfs:label "mesothelioma tumor lysate-pulsed autologous dendritic cell vaccine" ;
  rdfs:comment "A cell-based cancer vaccine consisting of autologous dendritic cells (DCs) pulsed with mesothelioma tumor lysate with potential immunostimulating and antineoplastic activities. Upon administration, mesothelioma tumor lysate-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount a specific cytotoxic T lymphocyte (CTL) response against mesothelioma tumor cells, resulting in tumor cell lysis. " ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0017449 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y / tetanus toxoid vaccine, inactivated Injectable Solution [Nimenrix]" ;
  rdfs:subClassOf obo:VO_0017448 , obo:VO_0017920 .

obo:VO_0011492 a rdfs:Class ;
  rdfs:label "Trypanosoma brucei subunit p15 Protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012184 .

obo:VO_0002031 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: )" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0018489 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 20 by Axicorp" ;
  rdfs:subClassOf obo:VO_0018459 .

obo:VO_0020533 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020827 .

obo:VO_0020532 a rdfs:Class ;
  rdfs:label "0.5 ML A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0020530 , obo:VO_0020686 .

obo:NCBITaxon_1980410 a rdfs:Class ;
  rdfs:label "Bunyavirales" ;
  rdfs:subClassOf obo:NCBITaxon_2497571 .

obo:VO_0002118 a rdfs:Class ;
  rdfs:label "Canine Distemper-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14D9.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002482 , obo:VO_0007748 .

obo:VO_0002535 a rdfs:Class ;
  rdfs:label "mce-3 from Mycobacterium tuberculosis" ;
  rdfs:comment "A mce-3 mutant in Mycobacterium tuberculosis is attenuated and provides protection against challenge for mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0007310 a rdfs:Class ;
  rdfs:label "Autologous OFA-iLRP RNA-Transfected Dendritic Cell Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous, mature monocyte-derived dendritic cells (DCs) transfected with oncofetal antigen immature laminin receptor protein (OFA-iLRP) RNA, with potential antineoplastic activity. Upon administration, DCs in the OFA-iLRP RNA-transfected autologous dendritic cell vaccine express, process, and present OFA-iLRP to the host immune system, which may mount a potent cytotoxic T-cell (CTL) response against OFA-iLRP-expressing tumor cells. As a highly conserved protein, OFA-iLRP is preferentially expressed in fetal tissues and in many types of cancer, including hematopoietic malignancies, but is not detectable in normal differentiated adult cells." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:OGG_2000000002 a rdfs:Class ;
  rdfs:label "gene of Bacteria" ;
  rdfs:comment "A gene of an organism of Bacteria" ;
  rdfs:subClassOf obo:OGG_0000000002 .

obo:VO_0001255 a rdfs:Class ;
  rdfs:label "polysaccharide subunit vaccine" ;
  rdfs:comment "a subunit vaccine that uses polysaccharide as protective antigen" ;
  rdfs:subClassOf obo:VO_0000534 .

obo:VO_0020377 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0020359 , obo:VO_0020367 , obo:VO_0020383 .

obo:VO_0016733 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016719 .

obo:VO_0017677 a rdfs:Class ;
  rdfs:label "hepatitis B virus subtype ADW2 HBsAg surface protein antigen" ;
  rdfs:subClassOf obo:VO_0011093 .

obo:VO_0020297 a rdfs:Class ;
  rdfs:label "yellow fever virus strain 17D-204 live antigen 4000 UNT/ML Injection [YF-Vax]" ;
  rdfs:subClassOf obo:VO_0020296 .

obo:VO_0003060 a rdfs:Class ;
  rdfs:label "Monkeypox virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Monkeypox virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003539 .

obo:VO_0003428 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 2000000000 UNT [Vivotif]" ;
  rdfs:subClassOf obo:VO_0003353 .

obo:VO_0000975 a rdfs:Class ;
  rdfs:label "uropathogenic E. coli vaccine" ;
  rdfs:comment "An E. coli vaccine against uropathogenic E. coli infections" ;
  rdfs:subClassOf obo:VO_0000041 .

obo:VO_0003809 a rdfs:Class ;
  rdfs:label "FluMist Quadrivalent, 2015-2016 Formula Nasal Spray" ;
  rdfs:subClassOf obo:VO_0003806 .

obo:VO_0017032 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017031 , obo:VO_0017507 .

obo:VO_0007013 a rdfs:Class ;
  rdfs:label "Recombinant Anti-WT1 Immunotherapeutic GSK2302024A Vaccine" ;
  rdfs:comment "An immunotherapeutic composed of the Wilms tumor 1 (WT1) and an as of yet undisclosed adjuvant, with potential antineoplastic activity. Upon administration, the immune system may be stimulated to exert a cytotoxic T-lymphocyte (CTL) response against WT1-expressing tumor cells. The adjuvant stimulates the immune system's response to WT1. WT1, a tumor-associated antigen (TAA) and transcription factor, is overexpressed in a variety of tumor cell types." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0001497 a rdfs:Class ;
  rdfs:label "infectious bursal disease virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Infectious Bursal Disease Virus (IBDV) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 , obo:VO_0001468 .

obo:OBI_0000444 a rdfs:Class ;
  rdfs:label "target of material addition role"@en ;
  rdfs:comment "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role (the target) receives the addition of another material entity."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0018136 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Vaccine 35000 PFU/ML / Rubella virus 1400 PFU/ML / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0010735 , obo:VO_0018242 .

obo:VO_0010370 a rdfs:Class ;
  rdfs:label "TDVAX (NDC 13533) vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0015941 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015638 , obo:VO_0015715 , obo:VO_0016039 .

obo:VO_0001439 a rdfs:Class ;
  rdfs:label "Human Respiratory Syncytial Virus gene" ;
  rdfs:comment "A viral gene that is from Human Respiratory Syncytial Virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0016213 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0015165 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0015164 .

obo:VO_0016424 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 25 by Mtk" ;
  rdfs:subClassOf obo:VO_0015970 .

obo:VO_0004509 a rdfs:Class ;
  rdfs:label "PRRSV DNA vaccine pIRESorf7/IL-2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001802 .

obo:IAO_8000005 a rdfs:Class ;
  rdfs:label "import ontology module"@en ;
  rdfs:comment "A subset ontology module that is intended to be imported from another ontology."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/extract> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:VO_0003628 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016-2017 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003627 .

obo:VO_0016160 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0017151 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 80" ;
  rdfs:subClassOf obo:VO_0017129 , obo:VO_0017609 .

obo:VO_0015581 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Gen Vax]" ;
  rdfs:subClassOf obo:VO_0015534 , obo:VO_0015597 .

obo:VO_0011120 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Hong Kong/1/68(H3N2))" ;
  rdfs:comment "Vaccination with HA-VRP derived from Influenza A virus (A/Hong Kong/1/68(H3N2)) did not strongly stimulate either neutralizing or IgG1 antibodies but did induce IgG2a antibodies. Expression of IgG2a antibodies in this context correlated with clearance of virus and increased protection against lethal influenza challenge [PubMed: 16960108]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0015172 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015164 .

obo:VO_0019727 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0020951 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML Nasal Spray [Flumist]" ;
  rdfs:subClassOf obo:VO_0020943 , obo:VO_0020950 .

obo:VO_0017343 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution [Repevax]" ;
  rdfs:subClassOf obo:VO_0017341 .

obo:VO_0000345 a rdfs:Class ;
  rdfs:label "Brucella melitensis WR201 vaccine" ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0005021 a rdfs:Class ;
  rdfs:label "pTPA-PA63-LAMP1 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pTPA-PA63-LAMP1." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019685 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0020045 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Fluarix 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020314 .

obo:VO_0002266 a rdfs:Class ;
  rdfs:label "Encephalomyelitis Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.23)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000541 , obo:VO_0000640 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0007748 .

obo:VO_0017376 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Dt Vaccinol]" ;
  rdfs:subClassOf obo:VO_0018786 .

obo:VO_0001433 a rdfs:Class ;
  rdfs:label "Feline immunodeficiency virus gene" ;
  rdfs:comment "A viral gene that is from Feline immunodeficiency virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0016830 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0016735 , obo:VO_0016779 .

obo:VO_0004736 a rdfs:Class ;
  rdfs:label "ALVAC-WNV-PrM/E (dogs and cats) vaccine" ;
  rdfs:subClassOf obo:VO_0000752 .

obo:VO_0018692 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 700000 PFU [Rotarix]" ;
  rdfs:subClassOf obo:VO_0010738 , obo:VO_0018691 .

obo:VO_0003365 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003364 .

obo:VO_0018274 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003857 .

obo:OPL_0000248 a rdfs:Class ;
  rdfs:label "erythrocytic merozoite stage" ;
  rdfs:comment "A merozoite stage in the apicomplexan lifecycle that occurrs in the bloodstream of a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000036 .

obo:VO_0017824 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML [Menjugate]" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0010726 , obo:VO_0018790 .

obo:VO_0019098 a rdfs:Class ;
  rdfs:label "pill" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:DOID_0050175 a rdfs:Class ;
  rdfs:label "tick-borne encephalitis"@en ;
  rdfs:comment "A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Tick-borne encephalitis virus (Orthoflavivirus encephalitidis), which is transmitted_by Ixodes ticks. The infection has_symptom drowsiness, has_symptom confusion, has_symptom sensory disturbances, and has_symptom paralysis."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0020906 a rdfs:Class ;
  rdfs:label "Influenza A virus / Influenza B virus Injectable Suspension [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0020903 .

obo:IAO_0000003 a rdfs:Class ;
  rdfs:label "measurement unit label"@en ;
  rdfs:comment "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:VO_0001272 a rdfs:Class ;
  rdfs:label "EtxB vaccine adjuvant" ;
  rdfs:comment "An E. coli LT toxin derived vaccine adjuvant composed of the B subunit of E. coli heat-labile toxin." ;
  rdfs:subClassOf obo:VO_0000388 .

obo:VO_0007280 a rdfs:Class ;
  rdfs:label "Autologous Colorectal Tumor Antigen-pulsed Dendritic Cell Vaccine" ;
  rdfs:comment "A dendritic cell (DC)-based cancer vaccine composed of autologous DCs pulsed with tumor cell lysates from a colorectal cancer patient containing tumor-associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous colorectal tumor antigen-pulsed DC vaccine exposes the immune system to colorectal tumor cell antigens, which may result in cytotoxic T-lymphocyte (CTL)-mediated immune responses against the colorectal cancer cells. This leads to cancer cell lysis. The tumor cell lysate contains a range of antigens that are essential for the neoplastic growth and survival of the cancer cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0018172 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 6 CELLS/ML" ;
  rdfs:subClassOf obo:VO_0015052 .

obo:VO_0020586 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Preflucel] by Baxter" ;
  rdfs:subClassOf obo:VO_0020583 .

obo:VO_0005010 a rdfs:Class ;
  rdfs:label "pSport-B-gal DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pSport-B-gal.  This plasmid contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0010901 a rdfs:Class ;
  rdfs:label "FHc" ;
  rdfs:comment "Purified FHc was used to vaccinate mice and evaluate their survival against challenge with active botulinum neurotoxin serotype F (BoNT/F).  Mice that received one injection of 5 microg or two injections of >or=0.04 microg of FHc were completely protected [PubMed: 18845829]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010762 .

obo:VO_0017172 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] Box of 10" ;
  rdfs:subClassOf obo:VO_0017171 , obo:VO_0017183 , obo:VO_0017621 .

obo:VO_0003473 a rdfs:Class ;
  rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010303 , obo:VO_0010415 .

obo:VO_0000941 a rdfs:Class ;
  rdfs:label "Apex-IHN vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000645 , obo:VO_0012165 .

obo:VO_0000779 a rdfs:Class ;
  rdfs:label "obsolete NP-VRP" ;
  rdfs:comment "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus NP protein." .

obo:VO_0020661 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst] Box of 5 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020660 .

obo:VO_0003432 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003430 .

obo:VO_0005411 a rdfs:Class ;
  rdfs:label "UNAIR Inactivated COVID-19 Vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Airlangga University" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005201 .

obo:VO_0015986 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015651 , obo:VO_0015675 , obo:VO_0016063 .

obo:VO_0020060 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0010885 a rdfs:Class ;
  rdfs:label "TC0512 outer membrane protein, putative" ;
  rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0512 showed significant levels of protection when compared to negative control animals.  At 9 days following challenge TC0512 showed a 73% reduction in the number of recoverable Chlamydia compared with vector only immunized controls  [PubMed: 17239501]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010795 .

obo:VO_0016307 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Organon" ;
  rdfs:subClassOf obo:VO_0015926 .

obo:VO_0016293 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0016027 .

obo:VO_0020901 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Viroflu]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0019387 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Quadracel]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003213 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0007727 a rdfs:Class ;
  rdfs:label "polyvalent melanoma vaccine" ;
  rdfs:comment "A cancer vaccine consisting of whole irradiated heterologous melanoma cells which express multiple melanoma-related antigens. Polyvalent melanoma vaccine may stimulate an antitumoral cytotoxic T-cell immune response in the host, resulting in inhibition of tumor cell proliferation and tumor cell death. Vaccines may make the body build an immune response and kill tumor cells. Interleukin-2 may stimulate a person's white blood cells to kill tumor cells. Interferon alfa-2b may interfere with the growth of tumor cells. Treatment with this combination may help treat melanoma. " ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0001366 a rdfs:Class ;
  rdfs:label "Caprine herpesvirus type 1 vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Caprine herpesvirus type 1 virus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003537 .

obo:VO_0001982 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002360 .

obo:VO_0005498 a rdfs:Class ;
  rdfs:label "nasopharyngeal cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against nasopharyngeal cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0018889 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0017199 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017198 .

obo:VO_0004557 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda DNA vaccine pCE6" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002506 .

obo:VO_0002960 a rdfs:Class ;
  rdfs:label "Feline immunodeficiency virus vif mutant vaccine" ;
  rdfs:comment "A vif mutant in feline immunodeficiency virus was attenuated and a vif-deleted FIV provirus DNA protected cats against challenge with the homologous FIV-PPR biological isolate." ;
  rdfs:subClassOf obo:VO_0001508 .

obo:VO_0017583 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 5.33 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017582 .

obo:VO_0006091 a rdfs:Class ;
  rdfs:label "Ebola unspecified" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000726 .

obo:GO_0006955 a rdfs:Class ;
  rdfs:label "immune response" ;
  rdfs:comment "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." ;
  rdfs:subClassOf obo:GO_0050896 .

obo:VO_0001880 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4019.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002333 .

obo:VO_0004333 a rdfs:Class ;
  rdfs:label "Human papillomavirus DNA vaccine E7SH DNA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000667 .

obo:VO_0005257 a rdfs:Class ;
  rdfs:label "COVID-19 inactivated vaccine by the Scientific and Technological Research Council of Turkey" ;
  rdfs:comment "A SARS-CoV-2 inactivated virus vaccine by the Scientific and Technological Research Council of Turkey adjuvanted by aluminum hydroxide and CpG ODN" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005201 .

obo:VO_0011108 a rdfs:Class ;
  rdfs:label "HPV L1" ;
  rdfs:comment "rAAV5, -8 and -9 vectors expressing an HPV16 L1/E7 fusion gene were generated and applied intranasally for combined prophylactic and therapeutic vaccination of mice.  Vaccination with the rAAV vectors led to a significant protection of animals against a challenge with different HPV tumour cell lines [PubMed: 20032542]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010786 .

obo:VO_0004071 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae RASV synthesizing PsaA vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0015728 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat] Box of 3" ;
  rdfs:subClassOf obo:VO_0015575 , obo:VO_0015799 .

obo:VO_0015722 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites] Box of 10" ;
  rdfs:subClassOf obo:VO_0015573 , obo:VO_0015795 .

obo:NCBITaxon_3052230 a rdfs:Class ;
  rdfs:label "Hepacivirus hominis" ;
  rdfs:subClassOf obo:NCBITaxon_11050 .

obo:VO_0019738 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Flublok Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020327 .

obo:VO_0003778 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003777 .

obo:VO_0004151 a rdfs:Class ;
  rdfs:label "yellow fever NS1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000123 .

obo:UBERON_0001045 a rdfs:Class ;
  rdfs:label "midgut" ;
  rdfs:comment "Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]." ;
  rdfs:subClassOf obo:UBERON_0004921 .

obo:VO_0000244 a rdfs:Class ;
  rdfs:label "hypersensitity to arginine" ;
  rdfs:subClassOf obo:VO_0000207 .

obo:VO_0002982 a rdfs:Class ;
  rdfs:label "Porcine respiratory and reproductive syndrome virus GP5 protein mutant vaccine" ;
  rdfs:comment "A mutation in the GP5 protein attenuates HP-PRRSV in piglets. This mutant (HuN4-F112) induces protection against challenge with wild type HP-PRRSV" ;
  rdfs:subClassOf obo:VO_0001511 .

obo:VO_0016902 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0016899 , obo:VO_0017279 .

obo:VO_0010437 a rdfs:Class ;
  rdfs:label "licensed human haemophilus influenzae serotype b vaccine" ;
  rdfs:comment "Haemophilus influenzae serotype b vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000662 .

obo:VO_0000995 a rdfs:Class ;
  rdfs:label "pVAC1 3.0 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pVAC1 3.0. The manufacturer is Invitrogen." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019781 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003638 .

obo:VO_0021131 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020345 .

obo:VO_0011216 a rdfs:Class ;
  rdfs:label "Fbp" ;
  rdfs:comment "The fibrinogen-binding protein (FgBP) reacted with serum taken from horses recovering from strangles and protected mice against lethal challenge from S. equi subsp. equi [PubMed: 9579073]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010816 .

obo:VO_0020727 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Solution [ImmuCyst] by Alliance" ;
  rdfs:subClassOf obo:VO_0020724 .

obo:VO_0012179 a rdfs:Class ;
  rdfs:label "Coccidioides vaccine" ;
  rdfs:comment "A vaccine that protects against Coccidioides spp." ;
  rdfs:subClassOf obo:VO_0000267 .

obo:VO_0004060 a rdfs:Class ;
  rdfs:label "Helicobacter pylori HspA Protein vaccine" ;
  rdfs:subClassOf obo:VO_0012181 .

obo:OPL_0000032 a rdfs:Class ;
  rdfs:label "Anopheles midgut" ;
  rdfs:comment "A midgut that is a part of or originated from an Anopheles mosquito." ;
  rdfs:subClassOf obo:UBERON_0001045 .

obo:VO_0015474 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii protein" ;
  rdfs:subClassOf obo:VO_0010771 .

obo:VO_0010757 a rdfs:Class ;
  rdfs:label "Bacillus anthracis protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:VO_0016586 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Paediatric]" ;
  rdfs:subClassOf obo:VO_0016582 , obo:VO_0016588 .

obo:VO_0020019 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0003212 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0002546 a rdfs:Class ;
  rdfs:label "trpD from Mycobacterium tuberculosis" ;
  rdfs:comment "A trpD mutant is highly attenuated in mice and induces more protection from challenge with wild type M. tuberculosis than that induced by the current vaccine BCG" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0002699 a rdfs:Class ;
  rdfs:label "UL23 from Bovine herpesvirus 1" ;
  rdfs:comment "A thymidine kinase-deficient mutant (B8-D53) showed no detectable thymidine kinase-inducing activity and was attenuated in calves. B8-D53 also induced protection from challenge with wild type BHV-1" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001424 .

obo:VO_0000673 a rdfs:Class ;
  rdfs:label "Shigella Sfl 124 vaccine" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0003972 a rdfs:Class ;
  rdfs:label "Pentacel vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003970 , obo:VO_0020832 .

obo:IAO_0000109 a rdfs:Class ;
  rdfs:label "measurement datum"@en ;
  rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:VO_0015833 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Fendrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015628 .

obo:VO_0020247 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.008 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0010210 , obo:VO_0010445 .

obo:VO_0001226 a rdfs:Class ;
  rdfs:label "Brucella melitensis DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000709 .

obo:VO_0018759 a rdfs:Class ;
  rdfs:label "Vaccine, Typh.-Paratyph.A & B Injectable Solution [Tab Impfstoff]" ;
  rdfs:subClassOf obo:VO_0018758 .

obo:VO_0001385 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi vaccine" ;
  rdfs:comment "A vaccine that protects against Trypanosoma cruzi." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0011525 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine encoding SAG1 protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:VO_0007304 a rdfs:Class ;
  rdfs:label "Autologous Lymphoma Cell/Autologous Dendritic Cell Electrofusion Hybrid Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine consisting of hybrid cells created by electrofusing autologous dendritic cells (DCs) and autologous lymphoma cells with potential immunostimulating and antitumor activities. Upon administration, autologous lymphoma cell/autologous dendritic cell electrofusion hybrid vaccine may stimulate the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against specific autologous lymphoma-associated antigens, resulting in lymphoma cell apoptosis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0021046 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection [Varilrix]" ;
  rdfs:subClassOf obo:VO_0003274 , obo:VO_0010746 .

obo:DOID_28 a rdfs:Class ;
  rdfs:label "endocrine system disease"@en ;
  rdfs:comment "A disease of anatomical entity that is located_in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body."@en ;
  rdfs:subClassOf obo:DOID_7 .

obo:VO_0003714 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010314 , obo:VO_0010415 .

obo:VO_0010356 a rdfs:Class ;
  rdfs:label "PREVNAR 20 vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000424 , obo:VO_0000556 .

obo:VO_0003685 a rdfs:Class ;
  rdfs:label "Fluvirin 2016-2017 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003682 .

obo:VO_0015106 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension [Havrix]" ;
  rdfs:subClassOf obo:VO_0015105 , obo:VO_0015276 .

obo:VO_0018508 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0018503 .

obo:VO_0021173 a rdfs:Class ;
  rdfs:label "0.3 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (XBB.1.5) 0.1 MG/ML Prefilled Syringe [Comirnaty 2023-2024]" ;
  rdfs:subClassOf obo:VO_0021171 .

obo:VO_0007601 a rdfs:Class ;
  rdfs:label "DNP-modified autologous vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0001002 a rdfs:Class ;
  rdfs:label "phCMV1 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label phCMV1.  This plasmid is 4200 base pairs long, has a CMV promoter, contains kanamycin and neomycin antibiotics resistance genes, and is manufactured by Genlantis." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0017123 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 5 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017122 .

obo:VO_0003032 a rdfs:Class ;
  rdfs:label "immune factor-induced control of intracellular replication of live attenuated vaccine" ;
  rdfs:subClassOf obo:VO_0000286 .

obo:VO_0005049 a rdfs:Class ;
  rdfs:label "proVAX DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label proVAX. This plasmid contains a CMV promoter and a hCG-beta leader sequence." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0004414 a rdfs:Class ;
  rdfs:label "C. tetani DNA vaccine pcDNA3tetC encoding fragment C" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000640 .

obo:NCBITaxon_11309 a rdfs:Class ;
  rdfs:label "unidentified influenza virus" ;
  rdfs:subClassOf obo:NCBITaxon_35324 .

obo:VO_0001428 a rdfs:Class ;
  rdfs:label "Yersinia ruckeri gene" ;
  rdfs:comment "A bacterial gene that is from Yersinia ruckeri." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0017251 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution [Repevax]" ;
  rdfs:subClassOf obo:VO_0017250 .

obo:VO_0020684 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML Injectable Suspension [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020676 , obo:VO_0020683 .

obo:VO_0005241 a rdfs:Class ;
  rdfs:label "MRT5500 vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine that is manufactured by Sanofi Pasteur" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0007570 a rdfs:Class ;
  rdfs:label "FrSh61 (MEA) VHL33 peptide vaccine" ;
  rdfs:comment "A peptide derived from the tumor suppressor protein Von Hippel-Lindau (VHL). This peptide, sequence: MEAGRPRPCCAR, was constructed based on a frameshift mutation of one of the VHL gene products; the more abundant protein VHLp18(MEA) (where MEA stands for three amino acids, Met-Glu-Ala). Vaccination with FrSh61(MEA)VHL33 peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0020673 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0020668 , obo:VO_0020752 .

obo:VO_0020179 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (human), inactivated 2.5 UNT/ML Injection [Imovax]" ;
  rdfs:subClassOf obo:VO_0020178 , obo:VO_0020181 .

obo:VO_0019830 a rdfs:Class ;
  rdfs:label "influenza A virus A/Norway/16606/2021 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Victoria/1/2020 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Austria/1359417/2021 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML [FluMist Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020354 .

obo:VO_0018369 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003344 .

obo:VO_0017586 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 8 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0003405 , obo:VO_0017648 .

obo:NCBITaxon_619591 a rdfs:Class ;
  rdfs:label "Monkeypox virus Zaire-96-I-16" ;
  rdfs:subClassOf obo:NCBITaxon_10244 .

obo:VO_0000594 a rdfs:Class ;
  rdfs:label "vaccine specific T cell mediated cytotoxicity" ;
  rdfs:subClassOf obo:VO_0000106 .

obo:VO_0000813 a rdfs:Class ;
  rdfs:label "USA licensed cattle vaccine" ;
  rdfs:comment "A cattle vaccine with license that is used in USA." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000643 , obo:VO_0007748 .

obo:VO_0016903 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017283 .

obo:VO_0007450 a rdfs:Class ;
  rdfs:label "human papillomavirus 16 E7 peptide/padre 965.10 vaccine" ;
  rdfs:comment "A synthetic agent derived from human papillomavirus (HPV) E7 nuclear protein which is used to produce vaccines against HPV infection and HPV-related neoplasms. HPV E7 oncogenic protein binds the retinoblastoma tumor suppressor protein, pRB, as well as a number of other cellular proteins, and serves as a transcriptional activator. This protein is important in the induction and maintenance of cellular transformation and is co-expressed in the majority of HPV-containing carcinomas. PADRE(R) is a proprietary family of molecules that enhances the immune systems response against an administered immunogen such as the HPV E7 nuclear protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0005149 a rdfs:Class ;
  rdfs:label "rDNA-expressed S SARS protein vaccine" ;
  rdfs:comment "A SARS DNA vaccine made from rDNA-expressed ectodomain of the S protein." ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0015715 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015572 , obo:VO_0015794 .

obo:VO_0010797 a rdfs:Class ;
  rdfs:label "Bovine Leukemia virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0010944 a rdfs:Class ;
  rdfs:label "Eae" ;
  rdfs:comment "EHEC strains produce intimin, an outer membrane adhesin encoded by the eae gene located in a chromosomal pathogenicity island termed the locus of enterocyte effacement [PubMed: 17258324]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0016014 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 25" ;
  rdfs:subClassOf obo:VO_0003262 .

obo:VO_0011215 a rdfs:Class ;
  rdfs:label "Sfs" ;
  rdfs:comment "Parts of the three recombinant proteins (FNZ (cell surface-bound fibronectin binding protein), SFS (secreted fibronectin binding protein), and EAG (alpha2-macroglobulin, albumin, and immunoglobulin G [IgG] binding protein)) were used to immunize mice, either subcutaneously or intranasally, prior to nasal challenge with S. equi subsp. equi. The adjuvant used was EtxB, a recombinant form of the B subunit of Escherichia coli heat-labile enterotoxin. It was shown that nasal colonization of S. equi subsp. equi and weight loss due to infection were significantly reduced after vaccination compared with a mock-vaccinated control group. This effect was more pronounced after intranasal vaccination than after subcutaneous vaccination; nearly complete eradication of nasal colonization was obtained after intranasal vaccination (P < 0.001) [PubMed: 15155624]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010816 .

obo:VO_0007225 a rdfs:Class ;
  rdfs:label "Allogeneic GM-CSF-secreting Tumor Vaccine PANC 10.05 pcDNA-1/GM-Neo" ;
  rdfs:comment "An allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with a plasmid carrying the gene for cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Allogeneic GM-CSF-secreting tumor vaccine PANC 10.05 pcDNA-1/GM-Neo secretes GM-CSF thereby activating dendritic cells, promoting antigen presentation to B- and T-cells, and promoting a cytotoxic T-lymphocyte (CTL) response. This may eventually kill tumor cells. The pancreatic tumor cells are derived from the PANC 10.05 tumor cell line." ;
  rdfs:subClassOf obo:VO_0005430 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0001794 a rdfs:Class ;
  rdfs:label "Haemophilus Parasuis Avirulent Live Culture Vaccine (USDA: 19J1.00)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000611 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0001545 a rdfs:Class ;
  rdfs:label "Feline Leukemia Killed Virus Vaccine (USDA: 1555.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0000843 , obo:VO_0007748 .

obo:VO_0000782 a rdfs:Class ;
  rdfs:label "VRP expressing VP30 vaccine" ;
  rdfs:comment "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP30 protein." ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0018013 a rdfs:Class ;
  rdfs:label "poliomyelitis virus type 1 brunhilde / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) Injectable Solution [Poliovaccine Ssi]" ;
  rdfs:subClassOf obo:VO_0018012 .

obo:VO_0017528 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0017521 .

obo:VO_0001664 a rdfs:Class ;
  rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.51)" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:VO_0019655 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019654 , obo:VO_0020489 .

obo:VO_0001619 a rdfs:Class ;
  rdfs:label "Bronchitis Mass & Ark Types, Killed Virus Vaccine (USDA: 1235.15)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0019376 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000946 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0002255 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4845.24)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002429 , obo:VO_0003143 , obo:VO_0007748 .

obo:OPL_0000260 a rdfs:Class ;
  rdfs:label "gamete stage" ;
  rdfs:comment "A life cycle stage of some parasites that develop into mature sexual cells." ;
  rdfs:subClassOf obo:UBERON_0000105 .

obo:VO_0010223 a rdfs:Class ;
  rdfs:label "zoster vaccine recombinant" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000635 , obo:VO_0000669 .

obo:VO_0015795 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015492 .

obo:VO_0017202 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017201 .

obo:VO_0003354 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Delayed Release Oral Capsule [Vivotif]" ;
  rdfs:subClassOf obo:VO_0003357 .

obo:VO_0010896 a rdfs:Class ;
  rdfs:label "Ssb" ;
  rdfs:comment "Mice vaccinated with candidate gene ssb showed significant reduction of spleen chlamydial loads as compared to nave, non-protected control mice (p 0.048).  This resulted in the ability of ssb to mediate a modest, but significant level of protection in an inbred A/J mouse respiratory challenge model [PubMed: 16434129]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010794 .

obo:VO_0001704 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0004185 a rdfs:Class ;
  rdfs:label "Salmonella DNA vaccine encoding SopB Protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000768 .

obo:VO_0007090 a rdfs:Class ;
  rdfs:label "Survivin Antigen Vaccine DPX-Survivac" ;
  rdfs:comment "A lipid depot-based therapeutic cancer vaccine composed of survivin epitopes, a universal T Helper peptide and a polynucleotide adjuvant encapsulated in liposomes and then formulated in the hydrophobic carrier Montanide ISA51 VG, with potential immunopotentiating and antineoplastic activities. Upon injection of the maveropepimut-S, a depot is created at the injection site from which the antigens and adjuvant are released. This vaccine may elicit a long lasting cellular response against survivin-expressing cancers, resulting in a decrease in tumor cell proliferation and an induction of tumor cell death. Survivin, a member of the inhibitor of apoptosis (IAP) family expressed during embryonic development, is upregulated in a variety of human cancers while absent in most normal adult cells; its expression in tumors is associated with a more aggressive phenotype, decreased survival, and increased resistance to chemotherapy." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0019382 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injectable Suspension [Pediarix]" ;
  rdfs:subClassOf obo:VO_0000082 , obo:VO_0017799 .

obo:VO_0011041 a rdfs:Class ;
  rdfs:label "US6 from Bovine herpesvirus 1" ;
  rdfs:comment "Calves were injected intranasally with either AdCMVgC or AdCMVgD (US6) or a combination of these two recombinants or a commercially available live vaccine for comparison. The highest BHV-1 neutralizing antibody titres were obtained with AdCMVgD (US6) followed by the live vaccine and to a lower extent with the combination of the two recombinants. Calves were protected against intranasal BHV-1 challenge performed 3 weeks after the second immunization [PubMed: 11818166]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010802 .

obo:VO_0001160 a rdfs:Class ;
  rdfs:label "vaccination dose specification" ;
  rdfs:subClassOf obo:OBI_0000969 .

obo:VO_0016878 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0016831 , obo:VO_0016838 .

obo:VO_0001593 a rdfs:Class ;
  rdfs:label "avian influenza H5N2 Subtype, Killed Virus Vaccine (USDA: 1057.H5)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0016841 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016762 .

obo:VO_0000363 a rdfs:Class ;
  rdfs:label "licensed vaccine" ;
  rdfs:comment "A vaccine that is licensed for commercial use." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0010836 a rdfs:Class ;
  rdfs:label "Leishmania infantum protein" ;
  rdfs:subClassOf obo:VO_0015478 .

obo:VO_0005268 a rdfs:Class ;
  rdfs:label "authorized COVID-19 recombinant adenoviral vector vaccine" ;
  rdfs:subClassOf obo:VO_0005200 , obo:VO_0005267 .

obo:PR_000015399 a rdfs:Class ;
  rdfs:label "superoxide dismutase [Cu-Zn]" ;
  rdfs:comment "A SODC domain protein that is a translation product of the human SOD1 gene or a 1:1 ortholog thereof." ;
  rdfs:subClassOf obo:PR_000000001 .

obo:VO_0007373 a rdfs:Class ;
  rdfs:label "Dendritic Cell-Recombinant Prostate-Specific Membrane Antigen Vaccine" ;
  rdfs:comment "A vaccine comprised of autologous dendritic cells pulsed with a recombinant prostate specific membrane antigen." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0002919 a rdfs:Class ;
  rdfs:label "obsolete S. dysenteriae 1 strain WRSd1" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" .

obo:VO_0018116 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Vaccine / Rubella virus vaccine / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018115 .

obo:VO_0016770 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0016719 .

obo:VO_0000561 a rdfs:Class ;
  rdfs:label "toxoid vaccine" ;
  rdfs:comment "A vaccine containing a toxoid, used to protect against toxins produced by certain bacteria. A toxoid (also called inactivated toxin) is a processed toxin that has been treated by chemical means, heat, or irradiation and is no longer capable of causing disease." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:VO_0017644 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [T Wellcovax]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0015260 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015252 .

obo:VO_0017546 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Tetamun] Box of 10" ;
  rdfs:subClassOf obo:VO_0017545 , obo:VO_0017547 .

obo:VO_0000092 a rdfs:Class ;
  rdfs:label "Fluzone Intradermal Quadrivalent" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0020770 a rdfs:Class ;
  rdfs:label "BCG, live, Tice strain 12.5 MG Injection [OncoTICE] by MSD" ;
  rdfs:subClassOf obo:VO_0020769 .

obo:VO_0017161 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Pediacel] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017160 .

obo:VO_0004129 a rdfs:Class ;
  rdfs:label "Q-VAX vaccine" ;
  rdfs:subClassOf obo:VO_0000463 .

obo:VO_0020618 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0020617 .

obo:VO_0005170 a rdfs:Class ;
  rdfs:label "GX-19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 DNA vaccine expressing the SARS-CoV-2 S protein" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0017753 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0017741 .

obo:VO_0004833 a rdfs:Class ;
  rdfs:label "Quadracel Injectable Product" ;
  rdfs:subClassOf obo:VO_0010736 .

obo:VO_0020374 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003849 .

obo:VO_0020008 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0017943 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017931 .

obo:OPL_0000028 a rdfs:Class ;
  rdfs:label "macrogametocyte stage" ;
  rdfs:comment "A gametocyte stage where a cell differentiates into a female sexual form called macrogametocyte." ;
  rdfs:subClassOf obo:OPL_0000150 .

obo:VO_0001176 a rdfs:Class ;
  rdfs:label "inactivated influenza vaccine" ;
  rdfs:comment "inactivated influenza vaccine is an inactivated viral vaccine that targets at influenza viral infections." ;
  rdfs:subClassOf obo:VO_0000642 , obo:VO_0000712 .

obo:VO_0000052 a rdfs:Class ;
  rdfs:label "Havrix vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000646 , obo:VO_0000714 , obo:VO_0010438 .

obo:VO_0019200 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2016 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020488 .

obo:VO_0002442 a rdfs:Class ;
  rdfs:label "Infectious Salmon Anemia Virus Vaccine-Aeromonas Salmonicida-Vibrio Anguillarum-Ordalii-Salmonicida Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0000820 , obo:VO_0001462 , obo:VO_0001520 .

obo:VO_0000394 a rdfs:Class ;
  rdfs:label "Bordetella bronchiseptica vaccine" ;
  rdfs:comment "Bordetella bacterial vaccine that is used to protect against Bordetella bronchiseptica infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000587 .

obo:VO_0007644 a rdfs:Class ;
  rdfs:label "mouse/human gp10025-33 peptide plus CpG adjuvant; mouse/human gp100; mouse/human gp10025-33 peptide-pulsed DCs  vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0011340 a rdfs:Class ;
  rdfs:label "Rop2" ;
  rdfs:comment "A study  to examine the immunostimulatory properties of Leishmania infantum Hsp83 (83) to elicit humoral and cellular response against the Toxoplasma gondii Rop2 protein in an adjuvant-free vaccination system was conducted. Mice immunized with fusion Rop2-83 elicited a stronger humoral and cellular response in comparison to mice immunized with Rop2 alone, or a mix of LiHsp83 and Rop2. The fusion protein induced a Th1 type response, with predominance of specific IgG2a/IgG2c isotype and IFN-gamma secretions, whereas Rop2 alone or mixed with LiHsp83 produced a Th1/Th2 mixed response. Vaccination with fusion protein conferred a remarkable resistance against oral infection with ME49 cysts in C57BL/6 and C3H mice, in comparison to mice immunized with Rop2 alone or the protein mixture. Following lethal challenge, a significant survival rate was observed in Rop2-83 immunized Balb/c and C57BL/6 mice in comparison to control groups [PubMed: 16545504]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0010082 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi TSA-1" ;
  rdfs:comment "A TSA-1 protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0005009 a rdfs:Class ;
  rdfs:label "VCL-1632 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label VCL-1632. This plasmid contains a CMV promoter, kanamycin resistance gene, the murine Kappa constant region sequence, a translational enhancer, the murine IgG2a heavy-chain sequence, and a translation terminator. This plasmid is derived from pUC-18." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0017082 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] Box of 50 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017081 .

obo:VO_0000684 a rdfs:Class ;
  rdfs:label "vaccine transportation" ;
  rdfs:comment "Process of transporting vaccine from one place to another place." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0016116 a rdfs:Class ;
  rdfs:label "0.5 ML hepatitis B surface antigen vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Organon" ;
  rdfs:subClassOf obo:VO_0015872 .

obo:VO_0015975 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015644 , obo:VO_0016059 .

obo:VO_0021016 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution [Varilrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0021014 , obo:VO_0021018 .

obo:VO_0001534 a rdfs:Class ;
  rdfs:label "Quail Pox Live Virus Vaccine (USDA: 18E1.10)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000513 , obo:VO_0000657 , obo:VO_0001220 , obo:VO_0007748 .

obo:DOID_4325 a rdfs:Class ;
  rdfs:label "Ebola virus disease"@en ;
  rdfs:comment "A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Bundibugyo virus (Orthoebolavirus bundibugyoense), Sudan ebolavirus (Orthoebolavirus sudanense), Tai Forest ebolavirus (Orthoebolavirus taiense), or Zaire ebolavirus (Orthoebolavirus zairense), which are transmitted_by contact with the body fluids of an infected animal or person, transmitted by contaminated fomites, or transmitted by infected medical equipment. The infection has_symptom fever, has_symptom headache, has_symptom joint pain, has_symptom muscle aches, has_symptom sore throat, has_symptom weakness, has_symptom diarrhea, has_symptom vomiting, has_symptom stomach pain, has_symptom rash, has_symptom red eyes, has_symptom hiccups, and has_symptom internal and external bleeding."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:NCBITaxon_10264 a rdfs:Class ;
  rdfs:label "Pigeonpox virus" ;
  rdfs:subClassOf obo:NCBITaxon_10260 .

obo:NCBITaxon_11118 a rdfs:Class ;
  rdfs:label "Coronaviridae" ;
  rdfs:subClassOf obo:NCBITaxon_76804 .

obo:VO_0004322 a rdfs:Class ;
  rdfs:label "IHNV DNA vaccine pCMV4-N encoding the nucleoprotein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012165 .

obo:VO_0011413 a rdfs:Class ;
  rdfs:label "Bordetella pertussis DNA vaccine encoding TcfA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000765 .

obo:VO_0011276 a rdfs:Class ;
  rdfs:label "SP" ;
  rdfs:comment "The potential protection of Lmjsp (Leishmania major signal peptidase) was evaluated in three different vaccination strategies (DNA/DNA, Protein/Protein and DNA/Protein), against L. major infection. We demonstrated that vaccination with SPase through all three mentioned strategies induced a parasite specific Th1 response and conferred partial protection against parasite challenge. However, our results indicated that DNA/DNA strategy developed more effective protective responses than the other two approaches and induced 81% reduction in L. major parasite load [PubMed: 16481076]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0002914 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium wecA mutant vaccine" ;
  rdfs:comment "A wecA mutant (DSM645) is attenuated in C57BL/6J mice through i.p. and oral immunization. This mutant also protects against challenge with S. typhimurium strains TML and SL1344 30 days after immunization" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0003882 a rdfs:Class ;
  rdfs:label "Flublok 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000978 , obo:VO_0010417 .

obo:VO_0019176 a rdfs:Class ;
  rdfs:label "0.5 ML hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0019506 .

obo:VO_0015225 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0015224 .

obo:VO_0020188 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0010738 , obo:VO_0020187 .

obo:VO_0007287 a rdfs:Class ;
  rdfs:label "Autologous Dendritic Cell-Autologous Tumor mRNA-Human CD40L Vaccine" ;
  rdfs:comment "cancer vaccine consisting of autologous dendritic cells transfected with autologous tumor mRNA and the human CD40 ligand (CD40L) gene with immunostimulatory and antitumor activities. Vaccination with autologous dendritic cell-autologous tumor mRNA-human CD40L vaccine may elicit a cytotoxic T cell response against tumor cells from which the autologous tumor mRNA was derived. When expressed by dendritic cells, tumor antigens and the co-stimulatory molecule CD40L, which binds to CD40 receptors on antigen presenting cells (APC), facilitate both humoral and cellular immune responses against tumor cells." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0018071 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018070 .

obo:VO_0004313 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine pcDNA3.1-SAG1-ROP2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:VO_0020459 a rdfs:Class ;
  rdfs:label "obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1 by Sanofi" .

obo:VO_0004550 a rdfs:Class ;
  rdfs:label "Feline immunodeficiency virus recombinant vector vaccine FIV-Delta-RT" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0001508 .

obo:VO_0003893 a rdfs:Class ;
  rdfs:label "Flublok 2016-2017 vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003891 .

obo:VO_0019326 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020103 .

obo:VO_0017296 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0018780 .

obo:VO_0004460 a rdfs:Class ;
  rdfs:label "Chinese Schistosoma japonicum DNA vaccine pVIVO2-IL12-Sj23 encoding Sj23 and IL-12" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001229 .

obo:VO_0004101 a rdfs:Class ;
  rdfs:label "MBP fused on Campylobacter FlaA (MBP-FlaA) vaccine" ;
  rdfs:subClassOf obo:VO_0012182 .

obo:VO_0002576 a rdfs:Class ;
  rdfs:label "asd from Burkholderia pseudomallei" ;
  rdfs:comment "An asd mutant is highly attenuated in mice. This mutant was also able to protect against acute inhalation melioidosis caused by challenge with wild type B. pseudomallei" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001411 .

obo:VO_0000517 a rdfs:Class ;
  rdfs:label "ETEC vaccine ACAM2017" ;
  rdfs:comment "ACAM2017 was derived from ACAM2007. Genes aroC, ompC, and ompF were deleted, while CS1 and pStrep were added." ;
  rdfs:subClassOf obo:VO_0000619 .

obo:VO_0010002 a rdfs:Class ;
  rdfs:label "Cp15 from Crptosporidium parvum" ;
  rdfs:comment "A Cp15 protein that is part of Crptosporidium parvum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010842 .

obo:VO_0003725 a rdfs:Class ;
  rdfs:label "Afluria 2016-2017 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003722 .

obo:VO_0011318 a rdfs:Class ;
  rdfs:label "RVFVsMgp1 M protein" ;
  rdfs:comment "The glycoprotein (GP) and nucleocapsid (NC) genes of Rift Valley fever virus (RVFV) were expressed in different expression systems and were evaluated for their ability to protect mice from virulent challenge using a prime-boost regime.  Mice vaccinated with a lumpy skin disease virus-vectored recombinant vaccine (rLSDV-RVFV) expressing the two RVFV glycoproteins (G1 and G2, expressed by the RVFV M Segment) developed neutralising antibodies and were fully protected when challenged, as were those vaccinated with a crude extract of truncated G2 glycoprotein (tG2) [PubMed: 16870311]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010849 .

obo:VO_0010887 a rdfs:Class ;
  rdfs:label "TC0439 adherence factor" ;
  rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0439 showed significant levels of protection when compared to negative control animals [PubMed: 17239501]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010795 .

obo:VO_0017832 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Prefilled Syringe [Begrivac]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017888 .

obo:VO_0000816 a rdfs:Class ;
  rdfs:label "biweekly" ;
  rdfs:subClassOf obo:PATO_0000044 .

obo:VO_0018665 a rdfs:Class ;
  rdfs:label "Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018663 , obo:VO_0020139 .

obo:VO_0018024 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 1000000 CELLS / poliovirus vaccine inactivated, type 2 (MEF-1) 100000 CELLS / poliovirus vaccine inactivated, type 3 (Saukett) 300000 CELLS [Polio Sabin-Rit Multi]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018046 .

obo:VO_0019240 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:VO_0002482 a rdfs:Class ;
  rdfs:label "Canine Distemper-Coronavirus-Parvovirus Vaccine" ;
  rdfs:subClassOf obo:VO_0002393 , obo:VO_0012178 .

obo:VO_0002844 a rdfs:Class ;
  rdfs:label "Francisella tularensis galU mutant vaccine" ;
  rdfs:comment "A galU mutant is attenuated in mice, with only transient weight loss observed. Two months after inoculation, mice were challenge with wild type F. tularensis and were protected, once again only experiencing transient weight loss" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0020962 a rdfs:Class ;
  rdfs:label "Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.00752 MG/ML" ;
  rdfs:subClassOf obo:VO_0003526 .

obo:VO_0018424 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumopur]" ;
  rdfs:subClassOf obo:VO_0018382 , obo:VO_0018383 , obo:VO_0018392 .

obo:VO_0004291 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine p188 encoding H7" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0003668 a rdfs:Class ;
  rdfs:label "YF-Vax 4000 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003669 .

obo:VO_0010788 a rdfs:Class ;
  rdfs:label "Rabies virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0019115 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010420 .

obo:VO_0001715 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.17)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0020152 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine Injection [Menveo]" ;
  rdfs:subClassOf obo:VO_0001246 , obo:VO_0010445 .

obo:VO_0001653 a rdfs:Class ;
  rdfs:label "Bursal Disease Standard & Variant, Killed Virus Vaccine (USDA: 12B5.40)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000960 , obo:VO_0007748 .

obo:VO_0015501 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen (isoform L), recombinant 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0004253 a rdfs:Class ;
  rdfs:label "inactivated H1N1(2009) vaccine with AF03 adjuvant" ;
  rdfs:subClassOf obo:VO_0001176 .

obo:VO_0010918 a rdfs:Class ;
  rdfs:label "Omp26" ;
  rdfs:comment "OMP26 was used to immunize rats via intestinal Peyer's patches, followed by an intratracheal boost. Immunization was found to significantly enhance bacterial clearance following pulmonary challenge with both the homologous NTHI strain and a different NTHI strain [PubMed: 9573117]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:VO_0004393 a rdfs:Class ;
  rdfs:label "Brucella abortus DNA vaccine pcDNA3-SOD encoding Cu-Zn SOD" ;
  rdfs:subClassOf obo:VO_0001225 .

obo:VO_0002103 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0015141 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015140 , obo:VO_0015144 , obo:VO_0015308 .

obo:VO_0015649 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection [H-B-Vax II]" ;
  rdfs:subClassOf obo:VO_0015544 , obo:VO_0019369 .

obo:VO_0007362 a rdfs:Class ;
  rdfs:label "CMV pp65 Peptide-pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with the human cytomegalovirus (CMV) phosphoprotein pp65, with potential immunostimulatory and antineoplastic activities. Upon administration, the CMV pp65 peptide-pulsed autologous DC vaccine exposes the immune system to the CMV pp65 peptide, which may result in a cytotoxic T-lymphocyte (CTL) response against CMV pp65-expressing tumor cells leading to cell lysis. The CMV pp65 protein, also called the 65 kDa lower matrix phosphoprotein, is the primary component of the enveloped subviral particle of CMV and is expressed in certain tumor types, such as glioblastoma" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0019543 a rdfs:Class ;
  rdfs:label "human-bovine reassortant rotavirus strain G1 vaccine 1100000 UNT/ML / human-bovine reassortant rotavirus strain G2 vaccine 1400000 UNT/ML / human-bovine reassortant rotavirus strain G3 vaccine 1100000 UNT/ML / human-bovine reassortant rotavirus strain G4 vaccine 1000000 UNT/ML / human-bovine reassortant rotavirus strain P1A[8] vaccine 1150000 UNT/ML Oral Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010449 .

obo:VO_0016914 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.0936 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetravac]" ;
  rdfs:subClassOf obo:VO_0016913 , obo:VO_0017295 .

obo:NCBITaxon_5800 a rdfs:Class ;
  rdfs:label "Eimeria" ;
  rdfs:subClassOf obo:NCBITaxon_423054 .

obo:VO_0000500 a rdfs:Class ;
  rdfs:label "infection disorder prevention" ;
  rdfs:comment "infection disorder prevention is a process that prevents a disorder that is the physical basis of an infectious disease." ;
  rdfs:subClassOf obo:VO_0000496 .

obo:VO_0016781 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016722 .

obo:VO_0018311 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0018284 .

obo:VO_0001953 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002360 .

obo:VO_0015068 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML" ;
  rdfs:subClassOf obo:VO_0015070 .

obo:VO_0016250 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016024 .

obo:VO_0020147 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0003441 , obo:VO_0010436 , obo:VO_0010444 .

obo:VO_0002450 a rdfs:Class ;
  rdfs:label "Mink Distemper-Enteritis Vaccine-Clostridium Botulinum Type C-Pseudomonas Aeruginosa Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000393 , obo:VO_0002449 .

obo:VO_0019822 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003594 , obo:VO_0019821 .

obo:VO_0007577 a rdfs:Class ;
  rdfs:label "obsolete Autologous Dendritic Cell-Tumor Fusion Vaccine" .

obo:VO_0017604 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0000721 a rdfs:Class ;
  rdfs:label "Brucella suis vaccine" ;
  rdfs:comment "a Brucella vaccine against infection wtih B. suis" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000025 .

obo:VO_0001340 a rdfs:Class ;
  rdfs:label "DHEA vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is DHEA, which is relatively stable and can be directly incorporated into vaccine formulations." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0016210 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0000935 a rdfs:Class ;
  rdfs:label "Sarcocystis neurona vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0001754 a rdfs:Class ;
  rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012180 .

obo:OPL_0000182 a rdfs:Class ;
  rdfs:label "Trypanosoma brucei trypomastigote" ;
  rdfs:comment "A Trypanosoma brucei that is a Trypomastigote form of Trypanosoma brucei. In this form the large kinetoplast is postnuclear and is at the most posterior part of the body and the flagellum emerges from the flagellar pocket, and runs along the entire length of the body as an undulating membrane." ;
  rdfs:subClassOf obo:NCBITaxon_5691 .

obo:VO_0000380 a rdfs:Class ;
  rdfs:label "subtenon vaccination" ;
  rdfs:comment "YH" ;
  rdfs:subClassOf obo:VO_0000002 .

obo:DOID_11054 a rdfs:Class ;
  rdfs:label "urinary bladder cancer"@en ;
  rdfs:comment "An urinary system cancer that results_in malignant growth located_in the urinary bladder."@en ;
  rdfs:subClassOf obo:DOID_3996 .

obo:VO_0020366 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Oral Powder [Vivotif]" ;
  rdfs:subClassOf obo:VO_0003353 , obo:VO_0020373 .

obo:VO_0015906 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25" ;
  rdfs:subClassOf obo:VO_0003267 .

obo:VO_0017764 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution [Tussoglobin] Box of 1" ;
  rdfs:subClassOf obo:VO_0017763 , obo:VO_0017765 .

obo:VO_0015592 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 50" ;
  rdfs:subClassOf obo:VO_0015528 , obo:VO_0015602 .

obo:VO_0003071 a rdfs:Class ;
  rdfs:label "FluLaval Quadrivalent" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0001562 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0000987 , obo:VO_0001220 .

obo:VO_0000107 a rdfs:Class ;
  rdfs:label "T cell vaccine antigen processing and presentation" ;
  rdfs:subClassOf obo:VO_0000106 .

obo:VO_0016644 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0016622 .

obo:VO_0001367 a rdfs:Class ;
  rdfs:label "heat-killed vaccine" ;
  rdfs:comment "an inactivation vaccine that is prepared by heat inactivation." ;
  rdfs:subClassOf obo:VO_0000017 .

obo:VO_0003533 a rdfs:Class ;
  rdfs:label "Yersiniaceae vaccine" ;
  rdfs:comment "Vaccine that protects against Yersiniaceae infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003551 .

obo:VO_0000422 a rdfs:Class ;
  rdfs:label "melanoma vaccine" ;
  rdfs:comment "A cancer vaccine that is used against melanoma, a malignant tumor of melanocytes." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0018029 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 2000000 CELLS/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 200000 CELLS/ML / poliovirus vaccine inactivated, type 3 (Saukett) 600000 CELLS/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020168 .

obo:VO_0015614 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015566 , obo:VO_0015659 .

obo:VO_0017352 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Dpt Merieux]" ;
  rdfs:subClassOf obo:VO_0017349 .

obo:VO_0002710 a rdfs:Class ;
  rdfs:label "vif from Feline immunodeficiency virus" ;
  rdfs:comment "A vif mutant in feline immunodeficiency virus was attenuated and FIV-pPPR delta vif proviral DNA protected cats against challenge with the homologous FIV-PPR biological isolate." ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001433 .

obo:VO_0019579 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2021 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020492 .

obo:VO_0007409 a rdfs:Class ;
  rdfs:label "Lapuleucel-T vaccine" ;
  rdfs:comment "A cell-based vaccine targets tumors expressing the HER2/neu marker. HER-2/neu is a growth factor receptor, and its overexpression has been associated with a number of cancers including breast, ovarian, colon and lung cancers. APC8024 comprise of autologous antigen-presenting peripheral blood mononuclear cells (APCs) that have been exposed to HER2/neu protein and can be administered to the patient. These cells may stimulate an antitumor T-cell response to cancer cells expressing HER2/neu." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0015654 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0015559 , obo:VO_0015600 .

obo:VO_0003129 a rdfs:Class ;
  rdfs:label "BCG vaccine SSI" ;
  rdfs:comment "Pharmacotherapeutic group (ATC code): J 07 AN 01." ;
  rdfs:subClassOf obo:VO_0000771 .

obo:VO_0010251 a rdfs:Class ;
  rdfs:label "vaccination route variable" ;
  rdfs:comment "A variable representing the vaccination route etc." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0004280 a rdfs:Class ;
  rdfs:label "Aflunov vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0002725 a rdfs:Class ;
  rdfs:label "US8 from Herpes simplex virus type 1 and 2" ;
  rdfs:comment "An HSV-1 gE (Us8) deletion strain, NS-gEnull, was used as a live attenuated vaccine. After HSV-1 challenge, latent virus was recovered by DRG explant cocultures from <10% of vaccinated mice compared with 100% of mock-vaccinated mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001437 .

obo:VO_0002104 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0017471 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003385 .

obo:VO_0020544 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Begripal] Box of 10" ;
  rdfs:subClassOf obo:VO_0020543 , obo:VO_0020603 , obo:VO_0020855 .

obo:VO_0011452 a rdfs:Class ;
  rdfs:label "Dengue vaccine using Vaccinia virus expressing prM protein" ;
  rdfs:subClassOf obo:VO_0000725 .

obo:VO_0002431 a rdfs:Class ;
  rdfs:label "horse EEV, VEV, WEV encephalomyelitis-West Nile Virus Vaccine-Tetanus Toxoid" ;
  rdfs:subClassOf obo:VO_0000541 , obo:VO_0002401 .

obo:VO_0018043 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 3 (Saukett) 300000 CELLS" ;
  rdfs:subClassOf obo:VO_0003837 .

obo:VO_0016253 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015918 .

obo:VO_0003439 a rdfs:Class ;
  rdfs:label "vaccine vector role" ;
  rdfs:comment "Vaccine component role inheres in a vaccine vector." ;
  rdfs:subClassOf obo:VO_0000617 .

obo:VO_0020623 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0020616 , obo:VO_0021037 .

obo:VO_0010970 a rdfs:Class ;
  rdfs:label "DnaK from Brucella" ;
  rdfs:comment "Brucella DnaK is a protective antigen [PubMed: 17686554]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0007674 a rdfs:Class ;
  rdfs:label "HPV E6/E7-encoding semliki forest virus vaccine Vvax001" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant, attenuated, replication-incompetent form of the Semliki Forest Virus (SFV) vector encoding the viral oncoproteins E6 and E7 derived from the human papillomavirus (HPV), with potential immunomodulating and antineoplastic activities. The vaccine induces expression of the E6/E7 proteins and stimulates both the innate and the adaptive immune system, resulting in a potent cytotoxic T-lymphocyte (CTL) response against and lysis of tumor cells expressing HPV E6 and E7. The vaccine may help to treat patients with a history of (pre) malignant cervical lesions." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0015694 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015567 , obo:VO_0015783 .

obo:VO_0011373 a rdfs:Class ;
  rdfs:label "Cancer DNA Vaccine pLXSHDmB7-2 encoding Cd86" ;
  rdfs:comment "Gene name: Cd86" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0011380 a rdfs:Class ;
  rdfs:label "Brucella abortus DNA vaccine encoding RplL and Omp16" ;
  rdfs:subClassOf obo:VO_0001225 .

obo:VO_0002194 a rdfs:Class ;
  rdfs:label "obsolete Porcine Circovirus Type 2, Killed Baculovirus Vector Vaccine (USDA: 19K5.R0)" .

obo:VO_0002908 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium rpoS mutant vaccine" ;
  rdfs:comment "Immunizations with Salmonella typhimurium rpoS and rpoS aroA mutants protected susceptible BALB/c mice against subsequent oral challenge with virulent S. typhimurium. When administered orally or intraperitoneally, rpoS derivatives of the mouse-virulent S. typhimurium strains, C52 and SL1344, were highly attenuated and were efficient single-dose live vaccines" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0020448 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typherix] Box of 1" ;
  rdfs:subClassOf obo:VO_0020411 , obo:VO_0020424 .

obo:VO_0010136 a rdfs:Class ;
  rdfs:label "Respiratory syncytial virus (RSV), vaccine, bivalent, protein subunit RSV prefusion F, diluent reconstituted, 0.5 mL, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000534 , obo:VO_0000635 , obo:VO_0000754 .

obo:VO_0018409 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 4 vaccine 0.004 MG" ;
  rdfs:subClassOf obo:VO_0003232 .

obo:VO_0002833 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda esrB mutant vaccine" ;
  rdfs:comment "An esrB mutant is highly attenuated in fish (turbot), with an LD50 of 10(8.1)cfu/fish. Vaccination with this mutant elicited significant protection from wild type E. tarda" ;
  rdfs:subClassOf obo:VO_0002506 .

obo:VO_0000069 a rdfs:Class ;
  rdfs:label "M-M-R II vaccine" ;
  rdfs:comment "A Measles-Mumps-Rubella vaccine that is live attenuated and manufactured by Merck & Co, Inc. " ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000641 , obo:VO_0000714 , obo:VO_0000731 , obo:VO_0001220 .

obo:NCBITaxon_11084 a rdfs:Class ;
  rdfs:label "Tick-borne encephalitis virus" ;
  rdfs:subClassOf obo:NCBITaxon_3044782 .

obo:VO_0017438 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0017435 , obo:VO_0020832 .

obo:VO_0020607 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 20 by Evans Vaccines" ;
  rdfs:subClassOf obo:VO_0020606 .

obo:VO_0010724 a rdfs:Class ;
  rdfs:label "Meningitec vaccine" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010444 .

obo:VO_0010839 a rdfs:Class ;
  rdfs:label "Chlamydophila psittaci protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0001035 a rdfs:Class ;
  rdfs:label "Yersinia ruckeri vaccine" ;
  rdfs:comment "a bacterial vaccine against Yersinia ruckeri infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000601 .

obo:VO_0007124 a rdfs:Class ;
  rdfs:label "Recombinant Adenovirus-hIFN-beta Vaccine" ;
  rdfs:comment "A recombinant replication-defective adenovirus which encodes the gene for the cytokine human interferon-beta (IFN-beta). Once inserted into and replicating in host tumor cells, recombinant adenovirus-hIFN-beta expresses human IFN-beta, which may stimulate an antiproliferative natural killer (NK) cell response against tumor cells and induce caspase-mediated tumor cell apoptosis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005491 , obo:VO_0007657 .

obo:VO_0016092 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015992 .

obo:VO_0007588 a rdfs:Class ;
  rdfs:label "BCG treatment after surgical tumor removal vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0004286 a rdfs:Class ;
  rdfs:label "recombinant Brucella abortus AsnC protein vaccine with CFA/IFA adjuvant" ;
  rdfs:subClassOf obo:VO_0000108 , obo:VO_0000484 .

obo:NCBITaxon_203692 a rdfs:Class ;
  rdfs:label "Spirochaetia" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:VO_0007449 a rdfs:Class ;
  rdfs:label "human papillomavirus -11 vaccine" ;
  rdfs:comment "A vaccine directed against Human Papillomavirus Type 11 that causes majority of the genital warts and anogenital cancers." ;
  rdfs:subClassOf obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0010482 a rdfs:Class ;
  rdfs:label "licensed human Yersinia pestis vaccine" ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000648 .

obo:VO_0019427 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus capsular oligosaccharide Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0010437 , obo:VO_0010445 .

obo:VO_0017093 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] Box of 5" ;
  rdfs:subClassOf obo:VO_0017088 , obo:VO_0017122 , obo:VO_0017566 .

obo:VO_0017690 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0017685 , obo:VO_0017744 .

obo:VO_0003184 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus vaccine foreign to USA" ;
  rdfs:comment "A Diphtheria-Tetanus-Pertussis-Poliovirus vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0000742 , obo:VO_0003444 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0020751 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension [Bcg Medac] Box of 1" ;
  rdfs:subClassOf obo:VO_0020750 , obo:VO_0020752 .

obo:VO_0019658 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0020303 .

obo:VO_0018495 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0018463 .

obo:VO_0016935 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adt Booster] Box of 5" ;
  rdfs:subClassOf obo:VO_0016934 , obo:VO_0016937 , obo:VO_0017397 .

obo:VO_0001942 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0002323 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4BC5.22)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002460 , obo:VO_0007748 .

obo:VO_0019218 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/11/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Delaware/55/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML / influenza B virus B/Singapore/WUH4618/2021 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020335 .

obo:VO_0015512 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [H B Vax]" ;
  rdfs:subClassOf obo:VO_0003256 .

obo:VO_0019610 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluad Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020313 .

obo:VO_0010157 a rdfs:Class ;
  rdfs:label "Diphtheria, Tetanus, Poliomyelitis adsorbed" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000943 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0010790 a rdfs:Class ;
  rdfs:label "Rubella virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0019435 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Haemophilus capsular oligosaccharide 0.02 MG/ML [HibTITER]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000659 , obo:VO_0001214 , obo:VO_0010437 , obo:VO_0010445 .

obo:VO_0004296 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pIRES/HA/IL-2 expressing HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0005004 a rdfs:Class ;
  rdfs:label "pCMV/R DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCMV/R. This plasmid is a mammalian expression vector with a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002042 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Variant, Serotype 3, Live Virus Vaccine (USDA: 1282.50)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:OBI_0000806 a rdfs:Class ;
  rdfs:label "material maintenance objective" ;
  rdfs:comment "An objective specification maintains some or all of the qualities of a material over time."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OPL_0000259 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum oocyst-derived sporozoite" ;
  rdfs:comment "A Plasmodium falciparum sporozoite that is found in the infected hepatocytes of a human host." ;
  rdfs:subClassOf obo:OPL_0000137 , obo:OPL_0000279 .

obo:VO_0002932 a rdfs:Class ;
  rdfs:label "obsolete Shigella sonnei virG/senA/senB mutant vaccine" ;
  rdfs:comment "A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei" .

obo:VO_0001293 a rdfs:Class ;
  rdfs:label "Gerbu vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant that is comprised of a mixture of GMDP, DDA, and Zinc L-proline salt complex (ZnPro8)." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0004776 a rdfs:Class ;
  rdfs:label "NYVAC-JEV vaccine" ;
  rdfs:subClassOf obo:VO_0000665 .

obo:VO_0002025 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4595.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002380 .

obo:VO_0003134 a rdfs:Class ;
  rdfs:label "YF-17D vaccine" ;
  rdfs:comment "A Yellow fever virus vaccine that uses the live attenated 17D strain." ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0010456 .

obo:VO_0002085 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass Type, Killed Virus Vaccine (USDA: 12M5.E0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0005246 a rdfs:Class ;
  rdfs:label "CoviVac (Vietnam)" ;
  rdfs:comment "A SARS-CoV-2 recombinant Newcastle Disease Virus vector vaccine expressing membrane-anchored pre-fusion-stabilized trimeric SARS-CoV-2 S protein" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0017309 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 4 LFU/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017302 .

obo:VO_0007321 a rdfs:Class ;
  rdfs:label "Autologous-Cell Leukemia Vaccine" ;
  rdfs:comment "An autologous therapeutic vaccine for the treatment of acute myelogenous leukemia. This vaccine is prepared from blood samples of patients following their first relapse. Tumor cells extracted from blood sample are modified with hapten, a process that makes the cells appear foreign to the patient's body and results in stimulating immune response against the cancer." ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0005487 , obo:VO_0007657 .

obo:NCBITaxon_359391 a rdfs:Class ;
  rdfs:label "Brucella abortus 2308" ;
  rdfs:subClassOf obo:NCBITaxon_235 .

obo:VO_0015032 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003302 .

obo:VO_0007474 a rdfs:Class ;
  rdfs:label "ESO-1 reactive autologous peripheral blood lymphocyte vaccine" ;
  rdfs:comment "Human peripheral blood lymphocytes (PBL) isolated from a patient, exposed to the tumor-associated protein ESO-1 in vitro, and then transferred back to the same patient to target tumor cells expressing ESO-1. ESO-1 is a human self-antigen expressed by melanomas. The ESO-1 gene encodes several MHC class I- and MHC class II-restricted epitopes that may activate cytotoxic T-cell-mediated tumor destruction" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:NCBITaxon_9796 a rdfs:Class ;
  rdfs:label "Equus caballus" ;
  rdfs:subClassOf obo:NCBITaxon_9788 .

obo:CHEBI_26710 a rdfs:Class ;
  rdfs:label "sodium chloride" ;
  rdfs:comment "An inorganic chloride salt having sodium(1+) as the counterion." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0019554 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020305 .

obo:VO_0000464 a rdfs:Class ;
  rdfs:label "protein of pathogen organism as vaccine component" ;
  rdfs:subClassOf obo:VO_0000000 .

obo:VO_0002619 a rdfs:Class ;
  rdfs:label "atpA from Salmonella Typhimurium" ;
  rdfs:comment "An atpA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0018728 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection [Typhim VI] Box of 10" ;
  rdfs:subClassOf obo:VO_0018727 , obo:VO_0018729 .

obo:VO_0018531 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension [Ixiaro] Box of 1 by Valneva" ;
  rdfs:subClassOf obo:VO_0018530 .

obo:VO_0015006 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Twinrix]" ;
  rdfs:subClassOf obo:VO_0003451 .

obo:VO_0005463 a rdfs:Class ;
  rdfs:label "influenza, intradermal, quadrivalent, preservative free, injectable" ;
  rdfs:subClassOf obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0001070 a rdfs:Class ;
  rdfs:label "E. coli vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector that uses an E. coli strain" ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0019290 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019960 .

obo:VO_0004126 a rdfs:Class ;
  rdfs:label "recombinant VEE Replicons expressing MBGV NP vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012163 .

obo:VO_0018340 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003334 .

obo:VO_0017944 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0017932 .

obo:VO_0000647 a rdfs:Class ;
  rdfs:label "licensed goat vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000363 .

obo:VO_0001756 a rdfs:Class ;
  rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012180 .

obo:VO_0011203 a rdfs:Class ;
  rdfs:label "CbpA" ;
  rdfs:comment "Mice were actively immunized with a fragment of choline binding protein A (CbpA; also known as PspC, Hic, and SpsA). CbpA was able to protect mice from intraperitoneal challenge with medium to very high doses of a highly virulent capsular type 2 pneumococcal strain, D39 [PubMed: 11553536]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0019961 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Afluria 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019941 .

obo:VO_0012363 a rdfs:Class ;
  rdfs:label "AY243312" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010764 .

obo:VO_0020094 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0003521 .

obo:VO_0001239 a rdfs:Class ;
  rdfs:label "RC529 vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant named RC529 that is a lipid A mimetic." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0004231 a rdfs:Class ;
  rdfs:label "Tetanus Toxoid vaccine with Stearyl Tyrosine" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000640 .

obo:VO_0001531 a rdfs:Class ;
  rdfs:label "Pigeon Pox Live Virus Vaccine (USDA: 1881.10)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001220 , obo:VO_0001481 , obo:VO_0007748 .

obo:VO_0007581 a rdfs:Class ;
  rdfs:label "Bacille Calmette Guerin for melanoma of lower extremity vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0001721 a rdfs:Class ;
  rdfs:label "Newcastle Disease VG/GA Strain, Live Virus Vaccine (USDA: 17A2.V1)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0004085 a rdfs:Class ;
  rdfs:label "ML29 vaccine" ;
  rdfs:subClassOf obo:VO_0012177 .

obo:VO_0007461 a rdfs:Class ;
  rdfs:label "GVAX Lung Cancer Vaccine" ;
  rdfs:comment "This is an autologous lung cancer vaccine consisting of patient-specific lung cancer cells genetically modified to secrete granulocyte-macrophage colony stimulating factor (GM-CSF), an immunostimulatory cytokine (NCIT_C1979). GM-CSF modulates the proliferation and differentiation of a variety of hematopoietic progenitor cells with some specificity towards stimulation of leukocyte production and may reverse treatment-induced neutropenias." ;
  rdfs:subClassOf obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0015734 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015805 .

obo:VO_0010165 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b conjugate and Hepatitis B vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000746 , obo:VO_0010437 , obo:VO_0010439 .

obo:VO_0016019 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015663 , obo:VO_0015817 .

obo:OPL_0000387 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii gametocyte" ;
  rdfs:comment "A Plasmodium yoelii in gametocyte stage." ;
  rdfs:subClassOf obo:NCBITaxon_5861 , obo:OPL_0000267 .

obo:VO_0001485 a rdfs:Class ;
  rdfs:label "USA licensed vaccine" ;
  rdfs:comment "A vaccine licensed in the USA" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000363 .

obo:VO_0020819 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen Injectable Solution [HibTITER]" ;
  rdfs:subClassOf obo:VO_0020818 .

obo:VO_0016203 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 50 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015903 .

obo:VO_0018854 a rdfs:Class ;
  rdfs:label "influenza B virus antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010301 , obo:VO_0010415 .

obo:VO_0019262 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0012396 a rdfs:Class ;
  rdfs:label "FbaA" ;
  rdfs:comment "Mice immunized with FbpA were protected from challenge with group A streptococcus [PubMed: 19254483]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012357 .

obo:VO_0004532 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi DNA vaccine encoding TSA-1 and Tc24" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001385 .

obo:VO_0019564 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flulaval Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003767 , obo:VO_0019544 .

obo:VO_0016162 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0015971 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 250" ;
  rdfs:subClassOf obo:VO_0003265 .

obo:VO_0007059 a rdfs:Class ;
  rdfs:label "WT1 247-261 peptide vaccine" ;
  rdfs:comment "A synthetic peptide vaccine consisting of a HLA-DRw53-restricted human Wilms' Tumor protein-1 (WT1) peptide comprised of amino acids 247 through 261, a HLA class II-restricted WT1 peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 247-261 peptide may stimulate a CD4-positive helper T-lymphocyte-mediated immune response against WT1 expressing cells. Activated helper T-cells stimulate dendritic cells, and activate the proliferation of other T-lymphoctes and B-lymphocytes. This causes tumor cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing tumor cells. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0005486 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0007318 a rdfs:Class ;
  rdfs:label "Autologous Tumor Cell Proteoliposome Chronic Lymphocytic Leukemia Vaccine" ;
  rdfs:comment "An autologous chronic lymphocytic leukemia cancer vaccine consisting of patient-specific membrane proteins directly extracted from patient autologous tumor cells and incorporated into liposomes along with Interleukin 2 (IL-2) to produce membrane-patched proteoliposomes, with potential immunostimulating and antineoplastic activities. After subcutaneous injection of the autologous tumor cell proteoliposomes chronic lymphocytic leukemia vaccine, liposomes deliver the encapsulated tumor antigens into the cytosol of antigen presenting cells (APCs). Subsequently, the APCs process the antigens and present antigen-derived peptides to the immune system. This may enhance recognition of tumors by the immune system, and activate both cytotoxic CD8+ T cells and CD4+ helper T cells against tumor cells. IL-2 is incorporated into the vaccine to leverage its ability to expand activated T cells." ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0004175 a rdfs:Class ;
  rdfs:label "Flagellin-based HA globular head fusion vaccine using HA protein from Influenza A virus (A/Viet Nam/1203/2004(H5N1))" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0003235 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010306 , obo:VO_0010415 .

obo:VO_0005056 a rdfs:Class ;
  rdfs:label "pUBIQ DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pUBIQ.  This plasmid is derived from pGEM3 and contains a CMV promoter and an ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:NCBITaxon_418103 a rdfs:Class ;
  rdfs:label "Plasmodium (Plasmodium)" ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0018055 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018054 .

obo:VO_0002807 a rdfs:Class ;
  rdfs:label "Bordetella pertussis aroA mutant vaccine" ;
  rdfs:comment "An aroA mutant is highly attenuated in mice and induces significant protection from challenge with wild type B. pertussis" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0006054 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent booster preservative free 10 mcg/0.2 mL dose" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0003003 a rdfs:Class ;
  rdfs:label "Western equine encephalomyelitis virus PE2/E1 or E2 mutant vaccine" ;
  rdfs:comment "A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur" ;
  rdfs:subClassOf obo:VO_0012188 .

obo:DOID_707 a rdfs:Class ;
  rdfs:label "B-cell lymphoma"@en ;
  rdfs:comment "A non-Hodgkin lymphoma that has_material_basis_in B cells."@en ;
  rdfs:subClassOf obo:DOID_0060058 .

obo:VO_0004940 a rdfs:Class ;
  rdfs:label "human age 6 months at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0020266 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 2 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0018030 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 2000000 CELLS/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 200000 CELLS/ML / poliovirus vaccine inactivated, type 3 (Saukett) 600000 CELLS/ML Injectable Suspension [Polio Sabin-S]" ;
  rdfs:subClassOf obo:VO_0018029 .

obo:VO_0016029 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0015667 , obo:VO_0015779 .

obo:VO_0015063 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:NCBITaxon_11229 a rdfs:Class ;
  rdfs:label "Morbillivirus" ;
  rdfs:subClassOf obo:NCBITaxon_2560076 .

obo:DOID_0060097 a rdfs:Class ;
  rdfs:label "thoracic benign neoplasm"@en ;
  rdfs:comment "An organ system benign neoplam that is located_in the thoracic cavity."@en ;
  rdfs:subClassOf obo:DOID_14566 , obo:DOID_7 .

obo:VO_0016677 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML [Tetravac]" ;
  rdfs:subClassOf obo:VO_0016704 .

obo:VO_0001348 a rdfs:Class ;
  rdfs:label "cholera toxin derived vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant that is derived from cholera toxin." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0015687 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 25" ;
  rdfs:subClassOf obo:VO_0015565 , obo:VO_0015780 .

obo:VO_0016724 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Diphtherie-Adsorbat-Impfstoff Behring]" ;
  rdfs:subClassOf obo:VO_0016709 , obo:VO_0016733 .

obo:VO_0003675 a rdfs:Class ;
  rdfs:label "Fluvirin 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000046 .

obo:VO_0020698 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1 MG/ML" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017679 .

obo:VO_0016148 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Europharma" ;
  rdfs:subClassOf obo:VO_0015886 .

obo:VO_0003573 a rdfs:Class ;
  rdfs:label "ProQuad vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003572 .

obo:VO_0001249 a rdfs:Class ;
  rdfs:label "RC529-AF vaccine adjuvant" ;
  rdfs:comment "An aqueous formula of the synthetic vaccine adjuvant RC529." ;
  rdfs:subClassOf obo:VO_0001239 .

obo:VO_0016119 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015873 .

obo:VO_0002766 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae apxIA mutant vaccine" ;
  rdfs:comment "The mutant strain, with deletion of apxIA gene, obtained in this study offered a level of cross-serovar protection against A. pleuropneumoniae infection in mice and pigs (Reference: PMID:16930871)." ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0007437 a rdfs:Class ;
  rdfs:label "HLA-Matched Donor Mononuclear Cell-Enriched Leukocytes Apocell vaccine" ;
  rdfs:comment "A preparation of allogeneic HLA-matched leukocytes treated with a derivative of placental protein 14 (PP14) with potential immunomodulating activity. PP14 derivative-treated HLA-matched donor mononuclear cell-enriched leukocytes contain at least fifty-five percent early-apoptotic T cells; after infusion and when processed by recipient dendritic cells, early-apoptotic T cells may help induce a decrease in the donor effector T-cell responses against the recipient of an allogeneic hematopoietic stem cell (HSC) transplant, thereby minimizing allogeneic HSC transplant-related graft-versus-host disease (GVHD). PP14, a 162 amino acid glycosylated protein secreted by the late secretory phase endometrium, binds to T cells in a carbohydrate fashion and has been shown to induce T-cell apoptosis; maternal immune tolerance to the fetus and pregnancy-related remissions of autoimmune disease may involve PP14-induced T cell apoptosis." ;
  rdfs:subClassOf obo:VO_0005503 .

obo:VO_0019704 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0000355 a rdfs:Class ;
  rdfs:label "pzz DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0018420 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML Injectable Solution [Pnu-Imune]" ;
  rdfs:subClassOf obo:VO_0018381 , obo:VO_0018388 .

obo:VO_0004543 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine expressing PA" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0002811 a rdfs:Class ;
  rdfs:label "diabetes vaccine" ;
  rdfs:comment "A vaccine that prevents or treats diabetes." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005503 .

obo:VO_0019423 a rdfs:Class ;
  rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.08 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 12 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0017302 .

obo:VO_0019225 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019742 .

obo:VO_0019145 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020813 .

obo:VO_0004340 a rdfs:Class ;
  rdfs:label "Classical swine fever virus DNA vaccine pCI-gp55" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001012 .

obo:VO_0011531 a rdfs:Class ;
  rdfs:label "influenza virus NP protein vaccine (influenza A virus (A/nt/60/1968(H3N2)))" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0001467 a rdfs:Class ;
  rdfs:label "dog vaccine" ;
  rdfs:comment "Vaccine that used for immunizing dog (Canis familiaris)." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001471 .

obo:VO_0006014 a rdfs:Class ;
  rdfs:label "hepatitis B vaccine adolescent/high risk infant dosage" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010439 .

obo:NCBITaxon_1239 a rdfs:Class ;
  rdfs:label "Bacillota" ;
  rdfs:subClassOf obo:NCBITaxon_1783272 .

obo:VO_0017745 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Pediacel] Box of 10" ;
  rdfs:subClassOf obo:VO_0017744 , obo:VO_0017751 .

obo:VO_0003253 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 7F vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0011362 a rdfs:Class ;
  rdfs:label "Cryptosporidium. parvum DNA vaccine encoding CP24" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012160 .

obo:VO_0001907 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4335.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002349 .

obo:VO_0017303 a rdfs:Class ;
  rdfs:label "Bordetella pertussis / diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension [Adacel]" ;
  rdfs:subClassOf obo:VO_0000005 , obo:VO_0017302 .

obo:VO_0011319 a rdfs:Class ;
  rdfs:label "RVFVsSgp2 N protein" ;
  rdfs:comment "Immunisation of mice with cDNA encoding the nucleocapsid protein induced strong humoral and lymphocyte proliferative immune responses.  Even though complete protection was not achieved by genetic immunisation, four out of eight mice vaccinated with cDNA encoding the nucleocapsid protein displayed no clinical signs of infection after challenge. In contrast, all fourteen control animals displayed clinical manifestations of Rift Valley Fever after challenge [PubMed: 19149901]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010849 .

obo:VO_0004500 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pCMVH5HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0019341 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0003441 , obo:VO_0010436 , obo:VO_0010444 .

obo:VO_0007507 a rdfs:Class ;
  rdfs:label "MART-1:27-35 peptide vaccine" ;
  rdfs:comment "A natural or synthetic peptide cancer vaccine consisting of amino acid residues 27 through 35 of the melanoma-associated antigen MART-1 with potential antineoplastic activity. Vaccination with MART-1:27-35 peptide may induce cytotoxic host immune responses against melanoma cells that express this peptide" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0000917 a rdfs:Class ;
  rdfs:label "polymyxin B vaccine allergen" ;
  rdfs:subClassOf obo:VO_0000910 .

obo:VO_0010081 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi Trans-salidase" ;
  rdfs:comment "A Trans-salidase protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0004821 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 1000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0004820 .

obo:VO_0019842 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003751 .

obo:VO_0000262 a rdfs:Class ;
  rdfs:label "pIRES DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002577 a rdfs:Class ;
  rdfs:label "purM from Burkholderia pseudomallei" ;
  rdfs:comment "Mice that were challenged with a higher dose of mutant 56:65 purM were protected" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001411 .

obo:VO_0003590 a rdfs:Class ;
  rdfs:label "Fluzone 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003589 .

obo:VO_0018777 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML / Bordetella pertussis 0.1 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0011322 a rdfs:Class ;
  rdfs:label "GEh29" ;
  rdfs:comment "80% of C3H/HeJ mice immunized with Eh29 administered in combination with a subclinical dose of whole cholera toxin, but not as an Eh29-CTxB fusion, showed no evidence of infection in tissue sections harvested following intracecal challenge with virulent E. histolytica trophozoites. These results suggest that Eh29 is capable of inducing protective anti-amoebic immune responses in mice following oral immunization and could be used in the development of oral vaccines against amoebiasis [PubMed: 20303954]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010852 .

obo:VO_0017705 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0017685 , obo:VO_0017752 .

obo:VO_0001017 a rdfs:Class ;
  rdfs:label "live attenuated Marek's disease virus vaccine" ;
  rdfs:comment "A live attenuated vaccine that protects against Marek's disease virus." ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0012162 .

obo:VO_0010969 a rdfs:Class ;
  rdfs:label "Tig" ;
  rdfs:comment "protective antigen [PubMed: 17239499]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0016626 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015003 .

obo:VO_0018083 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 25000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Injectable Suspension Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018082 .

obo:VO_0007718 a rdfs:Class ;
  rdfs:label "P501-AS15 vaccine" ;
  rdfs:comment "A cancer vaccine made up of CPC-P501 protein formulated with the adjuvant AS15. Patients with hormone-sensitive prostate cancer and rising PSA, after primary tumor treatment, can be treated with the P501-AS15 vaccine. " ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0020322 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2021-2022 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0000983 , obo:VO_0010423 .

obo:VO_0016780 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016732 .

obo:VO_0011426 a rdfs:Class ;
  rdfs:label "Chlamydophila psittaci DNA vaccine pcDNA2/MOMP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012174 .

obo:VO_0018004 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003213 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0003670 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML [YF-Vax]" ;
  rdfs:subClassOf obo:VO_0003665 .

obo:VO_0002590 a rdfs:Class ;
  rdfs:label "capB from Francisella tularensis" ;
  rdfs:comment "There was a deletion in gene capB of F. tularensis live vaccine strain. LVS capB, while much less virulent than LVS, induces potent protective immunity against lethal LVS i.n. challenge in mice, comparable to that induced by LVS" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0002314 a rdfs:Class ;
  rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49G6.24)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002465 , obo:VO_0007748 .

obo:VO_0020069 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluvirin 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020355 .

obo:VO_0000674 a rdfs:Class ;
  rdfs:label "recombinant SFL124-27 expressing Shigella dysenteriae type 1 O antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000681 .

obo:VO_0010116 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii ROP8" ;
  rdfs:comment "A ROP8 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0017800 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine Injectable Suspension [Acel-P]" ;
  rdfs:subClassOf obo:VO_0017799 .

obo:IAO_0000102 a rdfs:Class ;
  rdfs:label "data about an ontology part"@en ;
  rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:VO_0020170 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018046 .

obo:VO_0011506 a rdfs:Class ;
  rdfs:label "WEEV Subunit E2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012188 .

obo:VO_0010097 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA41" ;
  rdfs:comment "A GRA41 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0015513 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Hepasorbat]" ;
  rdfs:subClassOf obo:VO_0003256 .

obo:VO_0001647 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.19)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0020854 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Begripal]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020889 .

obo:VO_0001201 a rdfs:Class ;
  rdfs:label "Enterisol Ileitis vaccine" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001105 .

obo:VO_0016745 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Revaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0016711 , obo:VO_0016768 .

obo:VO_0007231 a rdfs:Class ;
  rdfs:label "allogeneic multipotent adult progenitor cells vaccine" ;
  rdfs:comment "A biologic product that consists of undifferentiated stem cells, obtained from adult bone marrow or other non-embryonic tissue sources, that are expanded in vitro and deposited in master cell banks for \"\"off-the-shelf\"\" use, with potential hematopoiesis-inducing and immunomodulating activities. Allogeneic multipotent adult progenitor cells (MAPCs) are non-immunogenic due to the lack of major histocompatibility (MHC) molecule expression, and so elicit no immune response upon administration. In vivo, bone marrow-derived adult stem cells are capable of maturing into a broad range of cell types and may help restore the immune system by producing multiple therapeutic molecules in response to inflammation and tissue damage." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0002003 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Hardjo Bacterin (USDA: 4L49.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002368 .

obo:IAO_8000004 a rdfs:Class ;
  rdfs:label "bridge ontology module"@en ;
  rdfs:comment "An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/inter-anatomy-ontology-bridge-ontologies> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:VO_0000471 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae vaccine" ;
  rdfs:subClassOf obo:VO_0012185 .

obo:VO_0016661 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0004999 a rdfs:Class ;
  rdfs:label "AKS-452 vaccine" ;
  rdfs:comment "A SARS-CoV-2-RBD-Fc fusion protein designed to induce or boost a Th1/Th2 mixed immune response in patients against the Receptor Binding Domain (RBD) of the novel coronavirus spike protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0016165 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0016003 .

obo:VO_0017771 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0017770 .

obo:VO_0019883 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Nasal Spray [Flumist 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019882 , obo:VO_0020350 .

obo:VO_0011073 a rdfs:Class ;
  rdfs:label "IglC2" ;
  rdfs:comment "Mice immunized with rLm/iglC were protected against lethal challenge with F. tularensis LVS administered by the intranasal route, a route chosen to mimic airborne infection, and, most importantly, against aerosol challenge with the highly virulent Type A F. tularensis SchuS4 strain [PubMed: 19126421]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:VO_0007190 a rdfs:Class ;
  rdfs:label "12MP, 12MP/Tet, 12MP/6MHP, or 6MHP vaccine" ;
  rdfs:comment "4 treatment groups, vaccinated with 12 MHC class I-restricted melanoma peptides to stimulate CTL (12 MP, group A), plus a tetanus peptide (group B), or a mixture of 6 melanoma helper peptides (6 MHP, group C) to stimulate helper T lymphocytes (HTL), or with 6 melanoma helper peptide (6 MHP) alone (group D), in incomplete Freund's adjuvant plus granulocyte macrophage colony-stimulating factor." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0019134 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010423 .

obo:VO_0001159 a rdfs:Class ;
  rdfs:label "PUREVAX Ferret Distemper vaccine" ;
  rdfs:comment "PUREVAX Ferret Distemper is a lyophilized ferret vaccine of a recombinant canarypox vector expressing the HA and F glycoproteins of canine distemper virus." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000653 , obo:VO_0012178 .

obo:VO_0018021 a rdfs:Class ;
  rdfs:label "Poliomyelitis Virus Type 3 (Sabin Strain (Leon 12a1b)) Live Attenuated Oral Vaccine 600000 UNT" ;
  rdfs:subClassOf obo:VO_0018020 .

obo:VO_0000102 a rdfs:Class ;
  rdfs:label "TENIVAC vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0011225 a rdfs:Class ;
  rdfs:label "MSP1 from P. berghei" ;
  rdfs:comment "Mice vaccinated with recombinant rMSP1 (rPbMSP1), which was generated from Plasmodium berghei, in alum mounted significant protective immunity against challenge infection (P < 0.01). On day 121 after the booster, three out of ten mice immunized with rPbMSP1 in PBS survived parasite infection (P < 0.05) and eight out of ten mice vaccinated with r MSP1 in alum did (P < 0.01). Hence, immunization with MSP1 in alum obviously has conferred protective effects, which prevented death from P. berghei lethal infection in mice (P < 0.01) [PubMed: 17568385]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015475 .

obo:VO_0006047 a rdfs:Class ;
  rdfs:label "respiratory syncytial virus monoclonal antibody (motavizumab) intramuscular" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000753 .

obo:VO_0017024 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0016995 , obo:VO_0017501 .

obo:VO_0018079 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 40" ;
  rdfs:subClassOf obo:VO_0018052 , obo:VO_0018159 .

obo:VO_0015868 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015614 , obo:VO_0015690 , obo:VO_0015992 .

obo:VO_0003014 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii OMPDC/UP mutant vaccine" ;
  rdfs:comment "An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii" ;
  rdfs:subClassOf obo:VO_0000994 .

obo:VO_0000943 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Poliovirus vaccine" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0000664 , obo:VO_0000732 .

obo:VO_0020149 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0020146 .

obo:VO_0000034 a rdfs:Class ;
  rdfs:label "obsolete Diphtheria and Tetanus Toxoids Adsorbed by Sanofi Pasteur Ltd" ;
  rdfs:comment "This term is obsolete since there is another term with the same meaning." .

obo:VO_0018525 a rdfs:Class ;
  rdfs:label "0.5 ML Anthrax Vaccine Adsorbed 0.1 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0004215 , obo:VO_0018596 .

obo:VO_0003787 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2016-2017 Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003785 .

obo:VO_0004669 a rdfs:Class ;
  rdfs:label "Streptococcus gordonii-TTFC vaccine" ;
  rdfs:subClassOf obo:VO_0000640 .

obo:VO_0002626 a rdfs:Class ;
  rdfs:label "cpxA from Salmonella Typhimurium" ;
  rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0003722 a rdfs:Class ;
  rdfs:label "Afluria 2016-2017 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003721 .

obo:VO_0001329 a rdfs:Class ;
  rdfs:label "resiquimod vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant, resiquimod is a chemical analog of imiquimod." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0000074 a rdfs:Class ;
  rdfs:label "Mumpsvax vaccine" ;
  rdfs:comment "Product Name: Mumps Virus Vaccine Live" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000656 , obo:VO_0010442 .

obo:VO_0004221 a rdfs:Class ;
  rdfs:label "Pasteurella multocida rOmpH vaccine" ;
  rdfs:subClassOf obo:VO_0000620 .

obo:VO_0015553 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Lt Grk]" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0016897 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.025 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0016896 , obo:VO_0017270 .

obo:VO_0010303 a rdfs:Class ;
  rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003501 , obo:VO_0010299 .

obo:VO_0004682 a rdfs:Class ;
  rdfs:label "rNDV-H5 ( HPAI H5N1 challenge in mule ducks) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0019249 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2021 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020492 .

obo:DOID_12549 a rdfs:Class ;
  rdfs:label "hepatitis A"@en ;
  rdfs:comment "A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis A virus (Hepatovirus ahepa), which is transmitted_by ingestion of contaminated food or water, or transmitted_by direct contact with an infected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:NCBITaxon_12083 a rdfs:Class ;
  rdfs:label "Poliovirus 2" ;
  rdfs:subClassOf obo:NCBITaxon_138950 .

obo:VO_0017453 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide 0.02 MG/ML / tetanus toxoid vaccine, inactivated 0.04 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010444 , obo:VO_0017673 .

obo:VO_0011185 a rdfs:Class ;
  rdfs:label "LctP" ;
  rdfs:comment "A total of 11 meningococcal proteins that are necessary for establishing systemic infection were expressed as recombinant antigens and assessed for their ability to protect mice against live bacterial challenge against N. meningitidis; the lactate permease (LctP) elicited protective immunity [PubMed: 15964482]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:NCBITaxon_76804 a rdfs:Class ;
  rdfs:label "Nidovirales" ;
  rdfs:subClassOf obo:NCBITaxon_2732506 .

obo:VO_0017966 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec] Box of 10" ;
  rdfs:subClassOf obo:VO_0017938 , obo:VO_0017950 .

obo:VO_0016363 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Axicorp" ;
  rdfs:subClassOf obo:VO_0016036 .

obo:VO_0004293 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pCMV/H7" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0007037 a rdfs:Class ;
  rdfs:label "recombinant Fowlpox-CEA(6D)/TRICOM vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). This agent may enhance CEA presentation to antigen presenting cells (APC) and activate cytotoxic T-cells against CEA-expressing tumors." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0018788 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0016417 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 3 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015960 , obo:VO_0015966 .

obo:VO_0010001 a rdfs:Class ;
  rdfs:label "Cp21 from Crptosporidium parvum" ;
  rdfs:comment "A Cp21 protein that is part of Crptosporidium parvum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010842 .

obo:VO_0005510 a rdfs:Class ;
  rdfs:label "EVAX-B vaccine adjuvant" ;
  rdfs:comment "Botryococcene oil-in-water emulsion vaccine adjuvant made by EVAX Inc., which targets to induce a mixed Th1/Th2 response." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0019843 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0019399 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.936 MG/ML / diphtheria toxoid vaccine, inactivated 13.4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017799 , obo:VO_0018770 .

obo:VO_0007521 a rdfs:Class ;
  rdfs:label "DIPG and GMB Immunomodulatory DC vaccine" ;
  rdfs:comment "A cancer vaccine based on ex vivo genetic modifications in combination with known tumor-specific antigens may substantially enhance the activation potential of tumor-specific T cells with improved benefit to patients. This DC vaccine is based on autologous DCs pulsed with genetically modified tumor cells or related antigens such as neoantigens to induce a strong anti-tumor immunity. The patient will receive intravenous cyclophosphamide (200 mg/m2) or oral (cytoxan) before the vaccine, followed by DC vaccine and intravenous bevacizumab (15 mg/kg)." ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 , obo:VO_0007658 .

obo:NCBITaxon_2732421 a rdfs:Class ;
  rdfs:label "Papovaviricetes" ;
  rdfs:subClassOf obo:NCBITaxon_2732415 .

obo:VO_0001111 a rdfs:Class ;
  rdfs:label "lumpy skin disease virus vaccine vector" ;
  rdfs:comment "A poxvirus vaccine vector that uses an attenuated lumpy skin disease virus as the vector.  " ;
  rdfs:subClassOf obo:VO_0001115 .

obo:NCBITaxon_1279 a rdfs:Class ;
  rdfs:label "Staphylococcus" ;
  rdfs:subClassOf obo:NCBITaxon_1385 .

obo:VO_0015760 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Gen Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015581 , obo:VO_0015817 .

obo:VO_0016923 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / pertactin adsorbed 0.005 MG/ML / Pertussis Vaccine 0.016 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017312 .

obo:VO_0003987 a rdfs:Class ;
  rdfs:label "Adacel 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003986 .

obo:VO_0000142 a rdfs:Class ;
  rdfs:label "incomplete Freund's adjuvant" ;
  rdfs:comment "A Freund's emulsified oil adjuvant that does not contain the mycobacterial components." ;
  rdfs:subClassOf obo:VO_0000133 .

obo:VO_0019636 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2022 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020494 .

obo:VO_0019453 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Decavac]" ;
  rdfs:subClassOf obo:VO_0000030 , obo:VO_0000561 , obo:VO_0001214 .

obo:VO_0018069 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 100 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018068 .

obo:VO_0003329 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 33F vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003249 .

obo:VO_0002053 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Standard & Variant, Serotype 3, Live Virus Vaccine (USDA: 12C8.43)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0001517 a rdfs:Class ;
  rdfs:label "Canarypox virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Canarypox virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000512 .

obo:OPL_0000287 a rdfs:Class ;
  rdfs:label "Plasmodium macrogamete stage" ;
  rdfs:comment "A macrogamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000085 , obo:OPL_0000286 .

obo:VO_0020218 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0020498 .

obo:VO_0015593 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015523 .

obo:VO_0001918 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4389.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002352 .

obo:NCBITaxon_520 a rdfs:Class ;
  rdfs:label "Bordetella pertussis" ;
  rdfs:subClassOf obo:NCBITaxon_517 .

obo:VO_0007640 a rdfs:Class ;
  rdfs:label "Melacine vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:MONDO_0005065 a rdfs:Class ;
  rdfs:label "mesothelioma" ;
  rdfs:comment "A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos." ;
  rdfs:subClassOf obo:DOID_14566 .

obo:VO_0020190 a rdfs:Class ;
  rdfs:label "rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018807 .

obo:VO_0020405 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0020387 , obo:VO_0020412 .

obo:VO_0018460 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumopur] Box of 1" ;
  rdfs:subClassOf obo:VO_0018434 , obo:VO_0018444 .

obo:VO_0015137 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015135 .

obo:VO_0019853 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Washington/19/2020 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0015232 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0010438 , obo:VO_0010451 , obo:VO_0015231 .

obo:NCBITaxon_642 a rdfs:Class ;
  rdfs:label "Aeromonas" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:VO_0003126 a rdfs:Class ;
  rdfs:label "FP85A vaccine" ;
  rdfs:comment "A TB vaccine that uses attenuated fowlpox strain FP9 to express mycobacterial mycolyl transferase Ag85A." ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0002162 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1771.14)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0003285 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000675 .

obo:VO_0021121 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.0857 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017850 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0003408 , obo:VO_0010437 .

obo:VO_0018308 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0018283 .

obo:VO_0010853 a rdfs:Class ;
  rdfs:label "Coccidioides spp. protein" ;
  rdfs:subClassOf obo:VO_0010756 .

obo:DOID_0080001 a rdfs:Class ;
  rdfs:label "bone disease"@en ;
  rdfs:comment "A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function."@en ;
  rdfs:subClassOf obo:DOID_65 .

obo:VO_0000997 a rdfs:Class ;
  rdfs:label "pSin-CMV-Vac DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pSin-CMV-Vac. The promoter is CMV." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019319 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluarix 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020315 .

obo:VO_0002330 a rdfs:Class ;
  rdfs:label "Bovine Parainfluenza 3-Respiratory Syncytial Virus vaccine" ;
  rdfs:subClassOf obo:VO_0000990 , obo:VO_0001507 .

obo:VO_0016329 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0007383 a rdfs:Class ;
  rdfs:label "Emepepimut-S vaccine" ;
  rdfs:comment "A liposome-encapsulated peptide vaccine consisting of a synthetic peptide derived from the mucin 1 (MUC-1) antigen with potential antineoplastic activity. Upon vaccination, MUC-1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against MUC-1-expressing tumor cells, resulting in growth inhibition. MUC-1 antigen is a high-molecular-weight transmembrane glycoprotein that is overexpressed on the cell surfaces of many epithelial tumor cells as well as on the cell surfaces of some B-cell lymphoma cells and multiple myeloma cells. (NCIT_C2195)." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0021161 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML Injection [Menveo]" ;
  rdfs:subClassOf obo:VO_0001246 , obo:VO_0010445 .

obo:VO_0000836 a rdfs:Class ;
  rdfs:label "Yersinia pestis YscF subunit vaccine" ;
  rdfs:comment "A Y. pestis subunit vaccine that uses Y. pestis YscF protein as antigen. PMID:15978133." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000648 .

obo:VO_0016615 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0016558 .

obo:VO_0012182 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni vaccine" ;
  rdfs:comment "A Campylobacter vaccine that protects against Campylobacter jejuni." ;
  rdfs:subClassOf obo:VO_0000568 .

obo:VO_0015960 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015734 , obo:VO_0015740 , obo:VO_0016050 .

obo:VO_0020594 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] by Sanofi" ;
  rdfs:subClassOf obo:VO_0020587 .

obo:VO_0004021 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding HA from influenza A virus (A/equine/Kentucky/1/1981(H3N8))" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0018632 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 12 BAU/ML [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0011558 , obo:VO_0018631 .

obo:VO_0019603 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020304 .

obo:VO_0017011 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 2" ;
  rdfs:subClassOf obo:VO_0017003 , obo:VO_0017022 , obo:VO_0017493 .

obo:VO_0004763 a rdfs:Class ;
  rdfs:label "rLSDV-RPV vaccine" ;
  rdfs:subClassOf obo:VO_0001455 .

obo:UBERON_0002385 a rdfs:Class ;
  rdfs:label "muscle tissue" ;
  rdfs:comment "Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]." ;
  rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0010000 .

obo:VO_0010150 a rdfs:Class ;
  rdfs:label "record of unknown vaccine or immune globulin" ;
  rdfs:comment "A record of missing knowledge indicating that vaccine or immune globulin is unknown." ;
  rdfs:subClassOf obo:OBI_0000852 .

obo:VO_0015879 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 25" ;
  rdfs:subClassOf obo:VO_0015617 , obo:VO_0016005 .

obo:VO_0001290 a rdfs:Class ;
  rdfs:label "cholera toxin A1-subunit-ProteinA D-fragment fusion protein" ;
  rdfs:comment "A microbial derivative vaccine adjuvant composed of the CTA1-DD fusion protein." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0015567 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015542 , obo:VO_0015596 .

obo:VO_0017480 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML [T Immun]" ;
  rdfs:subClassOf obo:VO_0017684 .

obo:VO_0005051 a rdfs:Class ;
  rdfs:label "pUSE- DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pUSE-.  This plasmid is a mammalian expression vector derived from pCI-neo." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015767 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Fendrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015587 .

obo:VO_0015014 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000627 , obo:VO_0001214 .

obo:VO_0020595 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Viroflu]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020880 .

obo:OGMS_0000063 a rdfs:Class ;
  rdfs:label "disease course" ;
  rdfs:comment "The totality of all processes through which a given disease instance is realized."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0002213 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002412 , obo:VO_0007748 .

obo:VO_0011321 a rdfs:Class ;
  rdfs:label "LcrV" ;
  rdfs:comment "Mice actively immunized using a recombinant V antigen (rVagHis, encoded by lcrV gene) of Y. enterocolitica were completely protected against challenge with both, Y. enterocolitica 0:8 and Y. pseudotuberculosis serotype III [PubMed: 10089162]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010851 .

obo:VO_0000135 a rdfs:Class ;
  rdfs:label "vaccine-induced adaptive immune response" ;
  rdfs:subClassOf obo:VO_0000287 .

obo:VO_0002537 a rdfs:Class ;
  rdfs:label "obsolete panC from Mycobacterium tuberculosis" ;
  rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" .

obo:OPL_0000246 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum hepatic merozoite stage" ;
  rdfs:comment "A hepatic merozoite stage in the Plasmodium falciparum lifecycle that occurs in the hepatocyte of a human host." ;
  rdfs:subClassOf obo:OPL_0000103 , obo:OPL_0000247 , obo:OPL_0000294 .

obo:VO_0003036 a rdfs:Class ;
  rdfs:label "sucrose vaccine stabilizer" ;
  rdfs:comment "a vaccine stabilizer that is specifically made by a sucrose. " ;
  rdfs:subClassOf obo:VO_0003034 .

obo:VO_0010427 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2015-2016" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0016579 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Hepatitis B Surface Antigen Vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000745 , obo:VO_0001214 .

obo:VO_0011378 a rdfs:Class ;
  rdfs:label "Bovine leukemia virus DNA vaccine encoding Env" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012161 .

obo:VO_0002325 a rdfs:Class ;
  rdfs:label "avian encephalomyelitis-chicken anemia virus-fowl pox vaccine" ;
  rdfs:subClassOf obo:VO_0001510 , obo:VO_0002326 .

obo:OPL_0000068 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum macrogametocyte stage" ;
  rdfs:comment "A macrogametocyte stage in the Plasmodium falciparum lifecycle that occurs either in the bloodstream of a human host or the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000028 , obo:OPL_0000192 , obo:OPL_0000290 .

obo:VO_0003426 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0015490 .

obo:VO_0018235 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Prefilled Syringe [Priorix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018234 , obo:VO_0018236 .

obo:VO_0007617 a rdfs:Class ;
  rdfs:label "human leukocyte antigen class I-modified peptide vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0017525 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] Box of 50" ;
  rdfs:subClassOf obo:VO_0017522 , obo:VO_0017528 .

obo:VO_0004503 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pCAGGHA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0016082 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015869 .

obo:VO_0019442 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 13.4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0012403 a rdfs:Class ;
  rdfs:label "Rib" ;
  rdfs:comment "Vaccination of mice with the Rib protein protected against two strains of capsular type III and two strains of type II, and vaccination with the alpha protein protected against one strain of type II and one strain of type Ib [PubMed: 8751893]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012356 .

obo:MONDO_0023644 a rdfs:Class ;
  rdfs:label "lip and oral cavity carcinoma" ;
  rdfs:comment "A carcinoma arising in the lip or oral cavity. Most oral cavity carcinomas are squamous cell carcinomas of the tongue, buccal mucosa, or gums. Less frequent morphologic variants include mucoepidermoid carcinoma and adenocarcinoma. Lip carcinomas are usually basal cell or squamous cell carcinomas." ;
  rdfs:subClassOf obo:DOID_1542 .

obo:VO_0000906 a rdfs:Class ;
  rdfs:label "Eimeria vaccine" ;
  rdfs:comment "Protozoan vaccine that is used to protect against Eimeria spp. (Eimeria) infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0005191 a rdfs:Class ;
  rdfs:label "MVA-SARS-2-S vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant vector vaccine that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein (S)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0004601 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae pspA-rBCG vector vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0011057 a rdfs:Class ;
  rdfs:label "GatC" ;
  rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #2, gatC) was found to be protective. Three of the clones (CP #1) elicited protection that was statistically higher than the unvaccinated control, which has high variance [PubMed: 15811648]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:VO_0020121 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain Injection [Attenuvax]" ;
  rdfs:subClassOf obo:VO_0000007 , obo:VO_0020120 .

obo:VO_0003793 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003791 .

obo:VO_0001959 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D7.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002362 .

obo:VO_0005424 a rdfs:Class ;
  rdfs:label "GLA-AF vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0000298 a rdfs:Class ;
  rdfs:label "pN4a-gal DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002835 a rdfs:Class ;
  rdfs:label "obsolete Edwardsiella tarda aroC/slyA mutant vaccine" ;
  rdfs:comment "An aroC and slyA mutant is attenuated in zebra fish. This mutant is also protective against challenge from wild type E. tarda, resulting in a relative percent survival of 80.1%" .

obo:VO_0002703 a rdfs:Class ;
  rdfs:label "E1 from Classical swine fever virus" ;
  rdfs:comment "An N to A amino acid substitution was made in the N594 site of the E1 glycoprotein, resulting in attenuation of the virus in swine. This attenuated virus induced protection against challenge with wild type CSFV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001430 .

obo:VO_0019561 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flucelvax Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020335 .

obo:VO_0017721 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 50" ;
  rdfs:subClassOf obo:VO_0017714 , obo:VO_0017727 , obo:VO_0017784 .

obo:VO_0017358 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017799 .

obo:VO_0019344 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen 0.12 MG/ML / Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020153 .

obo:VO_0016392 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0018883 a rdfs:Class ;
  rdfs:label "influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0010312 a rdfs:Class ;
  rdfs:label "Vibrio cholerae CVD 103-HGR strain live antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000763 , obo:VO_0001217 .

obo:DOID_4 a rdfs:Class ;
  rdfs:label "disease"@en ;
  rdfs:comment "A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:VO_0003025 a rdfs:Class ;
  rdfs:label "vaccine emulsifier role" ;
  rdfs:comment "a role inheres in the vaccine component when it is added into vaccine's formulation, it tends to stabilizes an emulsion by increasing its kinetic stablity." ;
  rdfs:subClassOf obo:VO_0000415 .

obo:VO_0018565 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection [Typhim VI] Box of 10" ;
  rdfs:subClassOf obo:VO_0018564 , obo:VO_0018566 .

obo:VO_0017950 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec] Box of 10" ;
  rdfs:subClassOf obo:VO_0017904 .

obo:VO_0010280 a rdfs:Class ;
  rdfs:label "vaccination frequency datum" ;
  rdfs:comment "A measurment datum that records the number of occurences the host was vaccinated as part of the vaccination process." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0000258 a rdfs:Class ;
  rdfs:label "pGA DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0020935 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Vaxigrip Junior]" ;
  rdfs:subClassOf obo:VO_0020929 .

obo:VO_0018182 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0018179 .

obo:VO_0007181 a rdfs:Class ;
  rdfs:label "PAX3/FKHR Peptide Vaccine" ;
  rdfs:comment "A synthetic peptide vaccine based on the sequences of a translocation mutation of 2 transcriptional factor genes, PAX3 and FKHR. PAX3/FKHR fusion proteins are frequently found in patients with rhabdomyosarcomas. Vaccination with PAX3/FKHR peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this PAX3/FKHR fusion protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0015126 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015292 .

obo:VO_0003762 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2016-2017 vaccine 0.5 Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003761 .

obo:VO_0001568 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001501 .

obo:VO_0010262 a rdfs:Class ;
  rdfs:label "host response to vaccine study design" ;
  rdfs:comment "A vaccine study design that is about the host response to a vaccine." ;
  rdfs:subClassOf obo:VO_0010261 .

obo:VO_0017000 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [T Immun] Box of 10 by Baxter" ;
  rdfs:subClassOf obo:VO_0016999 .

obo:VO_0006094 a rdfs:Class ;
  rdfs:label "CpG55.2 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant with a Toll-like receptor 9 (TLR9)-active oligonucleotide that is able to induce Th1/Th2 immune responses." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017448 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0010436 , obo:VO_0017815 , obo:VO_0017819 .

obo:VO_0019924 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Prefilled Syringe [Afluria 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019923 , obo:VO_0020300 .

obo:VO_0005163 a rdfs:Class ;
  rdfs:label "Sputnik V vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine composed of Ad26 and Ad5 vectors expressing S protein that lyophilised." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005268 .

obo:VO_0002341 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002342 .

obo:VO_0011080 a rdfs:Class ;
  rdfs:label "CWP2" ;
  rdfs:comment "The gene encoding the full length cyst wall protein-2 (CWP2) from Giardia lamblia was subcloned into the pCDNA3 mammalian expression vector and stably introduced into S. typhimurium STM1.  Challenge infection with live Giardia muris cysts revealed that mice receiving the CWP2-encoding DNA vaccine were able to reduce cyst shedding by approximately 60% compared to control mice [PubMed: 17996337]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010829 .

obo:VO_0017532 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 250 UNT/ML [Tetabulin]" ;
  rdfs:subClassOf obo:VO_0017531 .

obo:VO_0016123 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015878 .

obo:NCBITaxon_12264 a rdfs:Class ;
  rdfs:label "Cowpea mosaic virus" ;
  rdfs:subClassOf obo:NCBITaxon_464095 .

obo:VO_0005443 a rdfs:Class ;
  rdfs:label "licensed human hepatitis B immune globulin passive vaccine" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0020245 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Prefilled Syringe [Prevnar]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0017402 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 25 LFU/ML / Pertussis Vaccine 8 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution [Tri-Immunol Im]" ;
  rdfs:subClassOf obo:VO_0017357 , obo:VO_0017401 .

obo:VO_0020564 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Stada] by Mylan" ;
  rdfs:subClassOf obo:VO_0020561 .

obo:VO_0019741 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2023 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020496 .

obo:VO_0020989 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigens, strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain Nib-88 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0020988 .

obo:VO_0007343 a rdfs:Class ;
  rdfs:label "autologous total tumor mrna and CMV-pp65-flLAMP mRNA loaded liposome vaccine" ;
  rdfs:comment "A cancer vaccine consisting of total tumor RNA (TTRNA) derived and amplified from autologous tumor cells and mRNA encoding the human cytomegalovirus (CMV) matrix protein pp65 (65 kDa lower matrix phosphoprotein; UL83) as a fusion protein with the full-length lysosome-associated membrane protein (flLAMP), formulated in DOTAP lipid particles, with potential immunostimulatory and antineoplastic activities. he autologous total tumor mRNA and CMV-pp65-flLAMP mRNA loaded liposome vaccine, the mRNA is taken up, translated and presented by antigen presenting cells (APCs). This leads to an induction of both cytotoxic T-lymphocyte and memory T-cell dependent immune responses that specifically target and destroy the patient's cancer cells that express these tumor antigens. The incorporation of flLAMP may route CMV pp-65 antigens into the lysosomal compartment, resulting in enhanced MHC class II antigen presentation, thereby promoting CD4-positive T-cell responses. Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liposome vaccine is used to treat patients with Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM). The vaccine is also used for for the treatment of early melanoma recurrence following adjuvant Anti-PD-1 antibody therapy." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0011440 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum MSP3 protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000534 .

obo:VO_0019710 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0007689 a rdfs:Class ;
  rdfs:label "mature dendritic cell melanoma vaccine" ;
  rdfs:comment "A cancer vaccine that may elicit a cytotoxic T-cell (CTL) response against cancer cells. Autologous dendritic cells are pulsed with melanoma tumor-specific peptides. The mature dendritic cell (mDC3/8) vaccine (primer and booster) in patients with stage III and stage IV melanoma is followed by treatment with pembrolizumab (anti-PD-1 therapy). Using dendritic cells (a kind of white blood cell) as a vaccine could stimulate your own immune system to react to your melanoma cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0017955 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.5 MG / meningococcal group C polysaccharide 0.5 MG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.5 MG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.5 MG Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017819 .

obo:NCBITaxon_9654 a rdfs:Class ;
  rdfs:label "Procyon lotor" ;
  rdfs:subClassOf obo:NCBITaxon_3072906 .

obo:VO_0015816 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 50" ;
  rdfs:subClassOf obo:VO_0015496 .

obo:VO_0007515 a rdfs:Class ;
  rdfs:label "dendritic cell survivin vaccine" ;
  rdfs:comment "A cancer vaccine made using the participant's own blood cells. The vaccine will contain a virus called an adenovirus, similar the virus that causes the common cold. The dendritic cells contain survivin+, CD11c+, Human Leukocyte Antigen - antigen D Related (HLA-DR)+ by flow-cytometry. The vaccine is given in combination with G-CSF, T cells, and the CD34 progenitor cells." ;
  rdfs:subClassOf obo:VO_0005492 , obo:VO_0007657 , obo:VO_0007658 .

obo:NCBITaxon_33892 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis variant bovis BCG" ;
  rdfs:subClassOf obo:NCBITaxon_1765 .

obo:VO_0015471 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum protein" ;
  rdfs:subClassOf obo:VO_0010771 .

obo:OBI_0000675 a rdfs:Class ;
  rdfs:label "statistical hypothesis test objective"@en ;
  rdfs:comment "is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:VO_0010842 a rdfs:Class ;
  rdfs:label "Cryptosporidium parvum protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:NCBITaxon_13488 a rdfs:Class ;
  rdfs:label "Dicentrarchus" ;
  rdfs:subClassOf obo:NCBITaxon_1489388 .

obo:VO_0016481 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0020271 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003401 .

obo:VO_0018370 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG" ;
  rdfs:subClassOf obo:VO_0003345 .

obo:VO_0004805 a rdfs:Class ;
  rdfs:label "rVEE-Ebola-NP vaccine" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0005123 a rdfs:Class ;
  rdfs:label "VSVΔG-MERS vaccine" ;
  rdfs:comment "A MERS recombinant vector virus made from chimeric virus based on the vesicular stomatitis virus (VSV) in which the G gene was replaced by MERS-CoV S gene (VSV≈í√ÆG-MERS)." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0020369 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 10000000000 UNT" ;
  rdfs:subClassOf obo:VO_0003446 .

obo:VO_0004510 a rdfs:Class ;
  rdfs:label "PRRSV DNA vaccine pCI-ORF5/ORF6" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001802 .

obo:NCBITaxon_5811 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii" ;
  rdfs:subClassOf obo:NCBITaxon_5809 .

obo:VO_0003011 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii UIS3 mutant vaccine" ;
  rdfs:comment "Deletion of UIS3 in Plasmodium yoelii provided attenuation and full protection in mice by Pyuis3(-) sporozoites required at least 2 immunizations against challenges with infectious sporozoites" ;
  rdfs:subClassOf obo:VO_0002514 .

obo:VO_0001518 a rdfs:Class ;
  rdfs:label "Psittacid herpesvirus 1 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Psittacid herpesvirus 1 infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000727 .

obo:VO_0003386 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003201 .

obo:VO_0002684 a rdfs:Class ;
  rdfs:label "hemA from Vibrio cholerae" ;
  rdfs:comment "A hemA mutant is highly attenuated in mice and rabbits and induces protection from challenge with wild type V. cholerae in rabbits" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001423 .

obo:VO_0005811 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii irradiated sterilised tachyzoites vaccine" ;
  rdfs:comment "A Live attenuated vaccine irradiated sterilised tachyzoites that immunizes against Toxoplasma gondii trypmastigote." ;
  rdfs:subClassOf obo:VO_0000994 .

obo:VO_0000175 a rdfs:Class ;
  rdfs:label "pCEP4 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002277 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.01)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002461 , obo:VO_0007748 .

obo:VO_0019333 a rdfs:Class ;
  rdfs:label "0.5 ML measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0020118 .

obo:VO_0011147 a rdfs:Class ;
  rdfs:label "NS1 from Japanese encephalitis virus" ;
  rdfs:comment "Balb/c mice and swine vaccinated with TK(-)/gG(-)/NS1(+) expressing NS1 protein of JEV could confer protective immunity against lethal challenge of the virulent PRV Ea strain and develop a good humoral and cellular immune response against JEV [PubMed: 15121294]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010783 .

obo:VO_0001182 a rdfs:Class ;
  rdfs:label "vaccine strain role" ;
  rdfs:comment "a vaccine role that is borne by an organism strain serving as a vaccine" ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0020575 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Influsplit] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020574 .

obo:VO_0010705 a rdfs:Class ;
  rdfs:label "Actacel vaccine" ;
  rdfs:subClassOf obo:VO_0000714 , obo:VO_0003168 .

obo:VO_0010198 a rdfs:Class ;
  rdfs:label "influenza, Madin Darby Canine Kidney, subunit, trivalent, injectable, contains preservative" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000534 , obo:VO_0010415 .

obo:VO_0000847 a rdfs:Class ;
  rdfs:label "Plague vaccine USP" ;
  rdfs:comment "A formalin-inactivated preparation that was manufactured by Cutter Biologicals (a division of Miles Laboratories, Inc.). It is now available only from Greer Laboratories, Inc. The killed or inactivated plague vaccine is prepared from Y. pestis organisms grown in artificial media and then inactivated in formaldehyde." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010482 .

obo:VO_0002458 a rdfs:Class ;
  rdfs:label "Newcastle-Paramyxovirus vaccine" ;
  rdfs:subClassOf obo:VO_0001222 .

obo:VO_0015287 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML Injectable Solution [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015285 , obo:VO_0015286 .

obo:VO_0012171 a rdfs:Class ;
  rdfs:label "Entamoeba histolytica vaccine" ;
  rdfs:comment "A vaccine that protects against Entamoeba histolytica." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0018232 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018252 .

obo:VO_0001068 a rdfs:Class ;
  rdfs:label "Herpes simplex virus vaccine 1 vector" ;
  rdfs:comment "A Herpes simplex virus vaccine vector that uses a virus type 1 strain" ;
  rdfs:subClassOf obo:VO_0001046 .

obo:VO_0006072 a rdfs:Class ;
  rdfs:label "SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (Anhui Zhifei Longcom Biopharmaceutical + Institute of Microbiology Chinese Academy of Sciences)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0016499 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:VO_0000585 a rdfs:Class ;
  rdfs:label "immunization objective" ;
  rdfs:comment "immunization objective is the specification of an objective to achieve immunization." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:VO_0021098 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020489 .

obo:VO_0015958 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015732 , obo:VO_0015738 , obo:VO_0016048 .

obo:VO_0004010 a rdfs:Class ;
  rdfs:label "Neospora caninum NcDG1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001065 .

obo:DOID_10844 a rdfs:Class ;
  rdfs:label "Japanese encephalitis"@en ;
  rdfs:comment "A viral infectious disease that results_in infection located_in brain, has_material_basis_in Japanese encephalitis virus (Orthoflavivirus japonicum), which is transmitted_by Culex tritaeniorhynchus mosquito bite. The infection has_symptom headache, has_symptom high fever, has_symptom neck stiffness, has_symptom stupor, has_symptom disorientation, has_symptom coma, has_symptom tremors, has_symptom convulsions, and has_symptom spastic paralysis."@en ;
  rdfs:subClassOf obo:DOID_331 , obo:DOID_934 .

obo:VO_0004484 a rdfs:Class ;
  rdfs:label "Vaccinia virus DNA vaccine pWRG/L1R" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000651 .

obo:VO_0016249 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016023 .

obo:VO_0007257 a rdfs:Class ;
  rdfs:label "Anti-CD3 x Anti-CD20 Bispecific Antibody-Armed Activated T Cells Cancer Vaccine" ;
  rdfs:comment "Autologous activated T cells that have been coated with bispecific antibodies (BiAb), with potential antineoplastic and immunomodulating activities. In vitro, T cells are activated through exposure to the anti-CD3 murine monoclonal antibody OKT3 and low-dose interleukin 2 (Il-2) for 6-14 days and then armed with anti-CD3 x anti-CD20 bispecific antibody (CD20Bi). Upon administration, anti-CD3 x anti-CD20 bispecific antibody-armed activated T cells (AATC) attach to CD3-expressing T cells and CD20-expressing tumor cells, selectively cross-linking T cells and tumor cells. This may result in the recruitment and activation of cytotoxic T lymphocyte (CTLs), CTL-mediated specific tumor cell lysis, and the secretion of antitumor cytokines and chemokines. CD20, a cell surface phosphoprotein, is found on normal B cells and most B-cell tumors." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0020924 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.00752 MG/ML" ;
  rdfs:subClassOf obo:VO_0003502 , obo:VO_0004914 .

obo:VO_0007592 a rdfs:Class ;
  rdfs:label "obsolete CD80 Breast Cancer Vaccine" .

obo:VO_0017746 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Pediacel] Box of 20" ;
  rdfs:subClassOf obo:VO_0017744 , obo:VO_0017752 .

obo:VO_0016039 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015669 , obo:VO_0015794 .

obo:VO_0003494 a rdfs:Class ;
  rdfs:label "Spirochaetes vaccine" ;
  rdfs:comment "Vaccine that protects against Spirochaetes infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003553 .

obo:VO_0011459 a rdfs:Class ;
  rdfs:label "Canine distemper virus DNA vaccine encoding HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012178 .

obo:VO_0005011 a rdfs:Class ;
  rdfs:label "pSin-B-gal DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pSin-B-gal.  This plasmid contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0011174 a rdfs:Class ;
  rdfs:label "MIC3" ;
  rdfs:comment "Protective experiments of DNA vaccine pcDNA3-MIC3 (pMIC3i) in Kumming mice showed that the vaccine could significantly prolong the survival time of the mice challenged by virulent RH strains of T. gondii [PubMed: 19800170]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0016904 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.013 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Tripacel]" ;
  rdfs:subClassOf obo:VO_0016903 , obo:VO_0017284 .

obo:VO_0000879 a rdfs:Class ;
  rdfs:label "Porphyromonas denticanis" ;
  rdfs:subClassOf obo:NCBITaxon_836 .

obo:VO_0018747 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen Injection" ;
  rdfs:subClassOf obo:VO_0018715 .

obo:VO_0021043 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution [Zostavax]" ;
  rdfs:subClassOf obo:VO_0000124 , obo:VO_0021040 .

obo:VO_0000315 a rdfs:Class ;
  rdfs:label "inactivated vaccine" ;
  rdfs:comment "A whole organism vaccine that uses an inativated pathogen organism as its component." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:VO_0015499 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0005444 a rdfs:Class ;
  rdfs:label "licensed human immune globulin passive vaccine, intramuscular" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0003286 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003335 .

obo:VO_0011308 a rdfs:Class ;
  rdfs:label "Cp23 from Crptosporidium parvum" ;
  rdfs:comment "A Cp23 protein that is part of Crptosporidium parvum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010842 .

obo:VO_0001672 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001488 , obo:VO_0007748 .

obo:VO_0015298 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0010176 a rdfs:Class ;
  rdfs:label "influenza, live, trivalent, intranasal" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001178 , obo:VO_0010415 .

obo:DOID_0060058 a rdfs:Class ;
  rdfs:label "lymphoma"@en ;
  rdfs:comment "A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs."@en ;
  rdfs:subClassOf obo:DOID_0060073 , obo:DOID_2531 .

obo:VO_0003531 a rdfs:Class ;
  rdfs:label "Proteobacteria vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0018901 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen (isoform L), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform M), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform S), recombinant 0.01 MG/ML [Prehevbrio]" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0001944 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0017459 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 160 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [T Polio Adsorbed]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010447 , obo:VO_0017674 .

obo:VO_0000750 a rdfs:Class ;
  rdfs:label "Pseudorabies virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Pseudorabies virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003537 .

obo:VO_0002262 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza-West Nile Virus Eastern & Western, Killed Virus, Killed Flavivirus Chimera Vaccine-Tetanus Toxoid (USDA: 4855.R2)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002430 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0016561 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Twinrix]" ;
  rdfs:subClassOf obo:VO_0000113 , obo:VO_0016558 .

obo:OPL_0000279 a rdfs:Class ;
  rdfs:label "Plasmodium oocyst-derived sporozoite" ;
  rdfs:comment "A Plasmodium sporozoite that is found in the infected hepatocytes of a vertebrate host." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000278 .

obo:VO_0010782 a rdfs:Class ;
  rdfs:label "Influenza virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0001154 a rdfs:Class ;
  rdfs:label "Brucella abortus HSA-L7/L12 vaccine" ;
  rdfs:comment "B. abortus L7/L12 is a B. abortus subunit vaccine using L7/L12 that is formed by recombinant Human Serum Albumin (HAS)-L7/L12 fusion protein." ;
  rdfs:subClassOf obo:VO_0000323 .

obo:VO_0017718 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017717 .

obo:VO_0018628 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 1 UNT Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018626 , obo:VO_0018800 .

obo:VO_0000787 a rdfs:Class ;
  rdfs:label "obsolete gene" .

obo:VO_0017288 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML / Bordetella pertussis 0.1 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017227 .

obo:VO_0011481 a rdfs:Class ;
  rdfs:label "PCV2 DNA vaccine encoding ORF2 protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001524 .

obo:VO_0002790 a rdfs:Class ;
  rdfs:label "obsolete M. tuberculosis phoP mutant SO2" ;
  rdfs:comment "Study evaluated immunogenicity and protection against Mycobacterium tuberculosis in rhesus monkeys with an attenuated M. tuberculosis with a disrupted phoP gene (SO2) as a single-dose vaccine. SO2 treatment showed reduced average lung bacterial counts (1.0 and 1.2 log respectively, compared with 0.4 log for BCG) and significant protective effect by reduction in C-reactive protein levels, body weight loss, and decrease of erythrocyte-associated hematologic parameters (MCV, MCH, Hb, Ht) as markers of inflammatory infection, all relative to non-vaccinated controls" .

obo:VO_0017413 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Adt Booster]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0018795 .

obo:VO_0019812 a rdfs:Class ;
  rdfs:label "influenza A virus A/Kansas/14/2017 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Switzerland/3330/2017 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML [FluMist Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020351 .

obo:VO_0007472 a rdfs:Class ;
  rdfs:label "indium in 111-labeled autologous peripheral blood mononuclear cells vaccine" ;
  rdfs:comment "A preparation of autologous peripheral blood mononuclear cells (PBMCs) radiolabeled with indium In 111 with radioisotopic activity. Autologous PBMCs are isolated, expanded ex vivo, radiolabeled with indium In 111, and then infused back into the patient. Gamma scintigraphy may then be used to image gamma ray-emitting indium In 111 PBMCs localized in lymphoma tissue." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0005174 a rdfs:Class ;
  rdfs:label "bacTRL-Spike vaccine" ;
  rdfs:comment "A SARS-CoV-2 oral DNA vaccine that delivers plasmids containing synthetic DNA encoding spike protein from SARS-CoV-2." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0015647 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015582 , obo:VO_0015671 .

obo:VO_0000631 a rdfs:Class ;
  rdfs:label "vaccine in clinical trial role" ;
  rdfs:comment "A vaccine in clinical trial role is a regulation-assigned role that inheres in a vaccine that is currently in clinical trial." ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0015896 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015622 , obo:VO_0015623 , obo:VO_0015732 , obo:VO_0015738 , obo:VO_0016011 .

obo:VO_0007741 a rdfs:Class ;
  rdfs:label "tumor lysate/KLH pulsed dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine made from proteins from the patient's tumor cells may boost the body's immune response against the tumor. The effects of chemotherapy on the immune system can potentially make immunotherapy more effective if administered soon after completion of chemotherapy. The addition of recombinant human IL-7 (interleukin 7) (rhIL-7 (recombinant human interleukin 7)) may make the immunotherapy more effective. Alpha cluster of differentiation 25 (CD25) and 8H9 depleted autologous lymphocytes plus tumor lysate/keyhole limpet hemocyanin (KLH) pulsed dendritic cell vaccines plus or minus r-hIL7 (CYT107) may induce immune responses to tumor lysate in patients (with Ewing's sarcoma, rhabdomyosarcoma or neuroblastoma)." ;
  rdfs:subClassOf obo:VO_0005495 , obo:VO_0007657 , obo:VO_0007658 .

obo:IAO_8000009 a rdfs:Class ;
  rdfs:label "single layer subset ontology module"@en ;
  rdfs:comment "A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:VO_0002864 a rdfs:Class ;
  rdfs:label "Aro-deleted S. Typhi vaccine" ;
  rdfs:comment "Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ;
  rdfs:subClassOf obo:VO_0000671 .

obo:VO_0005454 a rdfs:Class ;
  rdfs:label "licensed human varicella zoster immune globulin passive vaccine" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0016120 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 20 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015874 .

obo:VO_0005813 a rdfs:Class ;
  rdfs:label "UV-attenuated Toxoplasma gondii vaccine with DSCG adjuvant" ;
  rdfs:comment "A Live attenuated vaccine with DSCG adjuvant that immunizes against Toxoplasma gondii trypmastigote." ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000994 .

obo:VO_0001705 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.12)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0016713 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0016676 , obo:VO_0016689 , obo:VO_0016719 .

obo:VO_0020739 a rdfs:Class ;
  rdfs:label "BCG, live, Connaught strain Injectable Suspension [InterVax]" ;
  rdfs:subClassOf obo:VO_0020737 .

obo:VO_0001863 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 16E5.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002437 , obo:VO_0007748 .

obo:VO_0004074 a rdfs:Class ;
  rdfs:label "BoNT/A(Hc) vaccine" ;
  rdfs:subClassOf obo:VO_0012187 .

obo:VO_0010745 a rdfs:Class ;
  rdfs:label "Vaqta vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000646 , obo:VO_0000712 , obo:VO_0000714 , obo:VO_0010438 .

obo:VO_0017692 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Pediacel] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017691 .

obo:VO_0011210 a rdfs:Class ;
  rdfs:label "SERA-5" ;
  rdfs:comment "Researchers constructed a new recombinant molecule of SERA5, namely SE36.  Vaccination of Squirrel monkeys with SE36 protein and aluminium hydroxyl gel (SE36/AHG) conferred protection against high parasitemia and boosted serum anti-SE36 IgG after P. falciparum parasite challenge [PubMed: 20493274]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0001020 a rdfs:Class ;
  rdfs:label "Advent vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:VO_0005134 a rdfs:Class ;
  rdfs:label "MVvac2-MERS-N vaccine" ;
  rdfs:comment "A MERS recombinant vector vaccine made of live-attenuated measles virus (MV) vaccine encoding the MERS-CoV nucleocapsid protein (MERS-N)." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0001282 a rdfs:Class ;
  rdfs:label "obsolete immunization target role of viral pathogen" .

obo:VO_0004405 a rdfs:Class ;
  rdfs:label "Autoimmune diabetes DNA vaccine pND2-GAD65-BAX encoding GAD and BAX" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002811 .

obo:VO_0020635 a rdfs:Class ;
  rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 PFU/ML Injectable Suspension [Zostavax] by Merck" ;
  rdfs:subClassOf obo:VO_0020634 .

obo:VO_0002763 a rdfs:Class ;
  rdfs:label "OMPDC from Toxoplasma gondii" ;
  rdfs:comment "An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001453 .

obo:VO_0015502 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.001 MG/ML [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015523 .

obo:VO_0005100 a rdfs:Class ;
  rdfs:label "SARS N protein DNA vaccine" ;
  rdfs:comment "A SARS DNA vaccine that is made from recombinant plasmid containing nucleocapsid protein (N) sequence constructed then expressed and purified from E. coli bacteria." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012183 .

obo:VO_0000708 a rdfs:Class ;
  rdfs:label "boost vaccination" ;
  rdfs:comment "A vaccination process that occurs after the primer vaccination with a purpose to boost host immune response to vaccine antigen." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0017426 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 50 LFU/ML / Pertussis Vaccine 24 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017349 .

obo:VO_0015025 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Tenivac]" ;
  rdfs:subClassOf obo:VO_0000102 .

obo:VO_0021024 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 PFU/ML" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0016650 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Europharma" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0007210 a rdfs:Class ;
  rdfs:label "Adenovirus-PSA Prostate Cancer Vaccine" ;
  rdfs:comment "A cancer vaccine composed of a genetically engineered, replication-deficient type 5 adenovirus carrying the human prostate-specific antigen (PSA), with potential immunostimulating and antineoplastic activities. Upon subcutaneous vaccination with the adenovirus-PSA prostate cancer vaccine, the adenovirus infects cells and expresses PSA. In turn, PSA may activate the immune system and may induce a cytotoxic T-lymphocyte response against PSA-expressing tumor cells. PSA, a tumor associated antigen, is expressed by prostate epithelial cells and is overexpressed in prostate cancer." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0003397 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003399 .

obo:VO_0015524 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0010327 .

obo:VO_0018381 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML [Pnu-Imune]" ;
  rdfs:subClassOf obo:VO_0003323 .

obo:VO_0018671 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 1000 MG Oral Suspension [Rotarix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018670 .

obo:VO_0012379 a rdfs:Class ;
  rdfs:label "GltA" ;
  rdfs:comment "Mice were immunised with the citrate synthase protein by intra-Peyer's patch immunisation. Pre-immunisation with the citrate synthase protein led to a 84-91% reduction in H. pylori infection compared to unimmunised controls [PubMed: 10378424]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010855 .

obo:VO_0020347 a rdfs:Class ;
  rdfs:label "FluMist 2010-2011 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000044 , obo:VO_0010426 .

obo:NCBITaxon_1280 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus" ;
  rdfs:subClassOf obo:NCBITaxon_1279 .

obo:VO_0020843 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Grippeimpfstoff Ratiopharm]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0010243 a rdfs:Class ;
  rdfs:label "assay type variable" ;
  rdfs:comment "A variable representing the assay type (ELISA, microarray) etc." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0003448 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Pill" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000487 .

obo:VO_0003798 a rdfs:Class ;
  rdfs:label "Varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML [Shingrix]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003317 .

obo:VO_0019434 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.036 MG/ML / Haemophilus capsular oligosaccharide 0.05 MG/ML Injectable Solution [Prohibit]" ;
  rdfs:subClassOf obo:VO_0019426 , obo:VO_0019433 .

obo:VO_0015670 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015493 .

obo:VO_0019625 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flulaval Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020343 .

obo:VO_0019489 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.005 MG/ML / meningococcal group C polysaccharide 0.01 MG/ML / meningococcal polysaccharide vaccine group Y 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0003192 , obo:VO_0010437 , obo:VO_0010444 , obo:VO_0020832 .

obo:VO_0000197 a rdfs:Class ;
  rdfs:label "obsolete West Nile virus gene" .

obo:VO_0018221 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018249 .

obo:VO_0015605 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Intramuscular Solution [Recombivax] by Merck" ;
  rdfs:subClassOf obo:VO_0015527 .

obo:VO_0020333 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2020-2021 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003070 , obo:VO_0010424 .

obo:VO_0020754 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain Injectable Solution [Pacis]" ;
  rdfs:subClassOf obo:VO_0020753 .

obo:VO_0016998 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [T Immun] Box of 1 by Baxter" ;
  rdfs:subClassOf obo:VO_0016997 .

obo:VO_0000236 a rdfs:Class ;
  rdfs:label "pCR4-TOPO DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0010314 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003498 , obo:VO_0010297 .

obo:VO_0007068 a rdfs:Class ;
  rdfs:label "RASVAC-V Vaccine" ;
  rdfs:comment "A synthetic vaccine used for cancer immunotherapy also known as Ras(val 12)-Vaccinia Vaccine, RASVAC-V is based on a mutant peptide epitope of the Ras oncoprotein at codon 12 (valine instead of glycine) that induces recognition and induction of tumor-specific, cell-mediated immune responses. Ras is an intracellular GTP-binding protein involved in signal transduction and regulation of proliferation and differentiation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0004800 a rdfs:Class ;
  rdfs:label "NYVAC-CSP malaria vaccine" ;
  rdfs:subClassOf obo:VO_0000761 .

obo:VO_0007731 a rdfs:Class ;
  rdfs:label "SCIB1 DNA vaccine" ;
  rdfs:comment "A cancer vaccine that encodes a melanoma antigen tyrosinase-related protein 2 (TRP2) cytotoxic T-lymphocyte (CTL) epitope and a modified monoclonal antibody, a chimera of human IgG1/murine IgG2a with T cell mimotopes expressed within the complementarity-determining regions (CDR) of the antibodies, with potential immunostimulating and antineoplastic activities. The melanoma TRP2 CTL epitope vaccine SCIB1 expresses the modified antibody. Subsequently, the Fc component of the engineered antibody targets and binds to the CD64 receptor on the dendritic cells (DCs); upon processing by DCs, the cellular immune system may be activated to induce helper T-cell and CTL immune responses against tumor cells expressing the TRP2 antigen. SCIB1 can be used in combination with either nivolumab (Opdivo) with ipilimumab (Yervoy) or pembrolizumab (Keytruda), standard treatments approved for patients with advanced melanoma." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0004473 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine 1040D2MEL encoding dengue-2 prM-E-LAMP chimeric protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:VO_0016238 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 1 by European" ;
  rdfs:subClassOf obo:VO_0016015 .

obo:VO_0016966 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Adt Vaccine]" ;
  rdfs:subClassOf obo:VO_0016963 , obo:VO_0017423 .

obo:VO_0011384 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae ApxIa and ApxIIa protein vaccine" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0011466 a rdfs:Class ;
  rdfs:label "Shigella flexneri Invaplex 24 subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000680 .

obo:VO_0019775 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019774 , obo:VO_0020310 .

obo:VO_0020228 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, vector non-replicating Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020227 .

obo:VO_0015488 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis Recombinant Fusion Protein Fhbp Group B" ;
  rdfs:subClassOf obo:VO_0003960 .

obo:VO_0015170 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Mevita" ;
  rdfs:subClassOf obo:VO_0015164 .

obo:OPL_0000264 a rdfs:Class ;
  rdfs:label "Plasmodium gamete" ;
  rdfs:comment "A Plasmodium that is found in the midgut of a mosquito vector during gamete lifecycle stage. There are two forms of gametes: micro- and macrogametocytes." ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0007359 a rdfs:Class ;
  rdfs:label "CEA RNA-pulsed Autologous Human Cultured Dendritic Cells Vaccine" ;
  rdfs:comment "Autologous human dendritic cells pulsed with RNA encoding the carcinoembryonic antigen (CEA) are being studied for possible use in the treatment of cancer expressing CEA." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0019322 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluvirin 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020471 .

obo:VO_0017902 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.3 MG/ML Injectable Suspension [Bexsero]" ;
  rdfs:subClassOf obo:VO_0017844 , obo:VO_0017929 .

obo:VO_0011164 a rdfs:Class ;
  rdfs:label "MDV040" ;
  rdfs:comment "Recombinant fowl poxviruses (rFPVs) were constructed to express genes from serotype 1 Marek's disease virus (MDV, Gallid herpesvirus 2).  rFPV/gB1 expressing MDV040 conferred 42% protection in maternal antibody-positive chickens when challenged with highly virulent MDV isolates [PubMed: 14562881]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010804 .

obo:VO_0000789 a rdfs:Class ;
  rdfs:label "DNA and Ad5/35 vector expressing HIV gp160 protein vaccine" ;
  rdfs:comment "A vaccine combination that includes a DNA vaccine and a replication-defective chimeric Ad5 vector with the Ad35 fiber (Ad5/35) that express the same codon-optimized SIV gag gene. The DNA vaccine is used for priming, and the Ad5/35 vaccine is used for boosting. PMID:16079886." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0001658 a rdfs:Class ;
  rdfs:label "Bursal Disease Variant, Killed Virus Vaccine (USDA: 12A5.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000960 , obo:VO_0007748 .

obo:VO_0011179 a rdfs:Class ;
  rdfs:label "PrM from West Nile virus" ;
  rdfs:comment "Starting with a previously designed eukaryotic expression vector, a recombinant plasmid (pCBWN) that expressed the WN virus prM and E proteins was constructed. A single intramuscular injection of pCBWN DNA induced protective immunity, preventing WN virus infection in mice and horses when subjected to challenge with the NY99-6480 strain of WNV [PubMed: 11287553]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010803 .

obo:VO_0010138 a rdfs:Class ;
  rdfs:label "Respiratory syncytial virus (RSV) monoclonal antibody, IgG1κ, (nirsevimab-alip), 1 mL, neonates and children to 24 months" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000753 , obo:VO_0000756 .

obo:VO_0020560 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippe-Impfstoff Csl] by bioCSL" ;
  rdfs:subClassOf obo:VO_0020557 .

obo:VO_0017977 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017954 .

obo:VO_0011045 a rdfs:Class ;
  rdfs:label "Peb1A" ;
  rdfs:comment "Chitosan-DNA vaccines were prepared by embedding pcDNA3.1(+)-cadF and pcDNA3.1(+)-peblA with chitosan respectively. The mice immunized with chitosan-DNA vaccines have generated high levels of IgA and IgG from the sera and IgA from the intestinal secretions and the P/N value went up to 20.58, 30.13 and 6.87 respectively. The chitosan-DNA vaccines induced strongest level of protection in BALB/c mice against challenge with C. jejuni HS:19 strain and the protective efficacies was 93.70 [PubMed: 18206008]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010765 .

obo:VO_0016951 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017408 .

obo:NCBITaxon_1769 a rdfs:Class ;
  rdfs:label "Mycobacterium leprae" ;
  rdfs:subClassOf obo:NCBITaxon_1763 .

obo:NCBITaxon_314147 a rdfs:Class ;
  rdfs:label "Glires" ;
  rdfs:subClassOf obo:NCBITaxon_314146 .

obo:VO_0018658 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection Box of 20" ;
  rdfs:subClassOf obo:VO_0018653 .

obo:VO_0003519 a rdfs:Class ;
  rdfs:label "human influenza B virus vaccine" ;
  rdfs:subClassOf obo:VO_0003495 .

obo:VO_0000654 a rdfs:Class ;
  rdfs:label "Measles virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Measles virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003543 .

obo:VO_0015885 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015619 , obo:VO_0016002 .

obo:VO_0020293 a rdfs:Class ;
  rdfs:label "Vibrio cholerae CVD 103-HGR strain live antigen Oral Suspension [Vaxchora]" ;
  rdfs:subClassOf obo:VO_0003082 , obo:VO_0020292 .

obo:VO_0000063 a rdfs:Class ;
  rdfs:label "Imovax Rabies (USA)" ;
  rdfs:comment "The Imovax(R) 9 Rabies Vaccine is a sterile, stable, freeze-dried 10 suspension of rabies virus prepared from strain PM-1503-3M." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010448 .

obo:VO_0010211 a rdfs:Class ;
  rdfs:label "pneumococcal conjugate vaccine, 13 valent" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000424 .

obo:VO_0002061 a rdfs:Class ;
  rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.E0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002385 , obo:VO_0007748 .

obo:VO_0016065 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015860 .

obo:VO_0012160 a rdfs:Class ;
  rdfs:label "Cryptosporidium parvum vaccine" ;
  rdfs:comment "A vaccine that protects against Cryptosporidium parvum." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0004290 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine BacPAKHA encoding EqfKY HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0007017 a rdfs:Class ;
  rdfs:label "Recombinant Vaccinia DF3/MUC1 Vaccine" ;
  rdfs:comment "A vaccinia virus based vaccine expressing human tumor associated epithelial mucin (DF3 antigen; MUC1). MUC1 antigen, a membrane bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in various tumors such as breast, prostate, and ovarian cancers. This vaccine could be used in development of immunotherapeutics against cancers expressing MUC1." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0015529 a rdfs:Class ;
  rdfs:label "Haemophilus B Conjugate Vaccine / Hepatitis B Surface Antigen Vaccine Injectable Solution [Procomvax]" ;
  rdfs:subClassOf obo:VO_0015556 .

obo:VO_0011206 a rdfs:Class ;
  rdfs:label "Gnd" ;
  rdfs:comment "BALB/c mice were immunized with recombinant 6-Phosphogluconate dehydrogenase (r6PGD) and boosted after 3 weeks. Immunized mice were challenged intranasally with a lethal dose of S. pneumoniae. Immunization of mice with r6PGD protected 60% (P < 0.001) of mice for 5 days and 40% (P < 0.05) of the mice for 21 days following intranasal lethal challenge [PubMed: 16634799]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0004106 a rdfs:Class ;
  rdfs:label "MVA85A prime and BCG boost vaccine" ;
  rdfs:subClassOf obo:VO_0000077 .

obo:VO_0003459 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated 50 UNT/ML [Vaqta]" ;
  rdfs:subClassOf obo:VO_0010745 .

obo:VO_0021104 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluad Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020313 .

obo:VO_0006019 a rdfs:Class ;
  rdfs:label "Historical record of a typhus vaccination" ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0015789 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015491 .

obo:VO_0015085 a rdfs:Class ;
  rdfs:label "influenza A virus (H3N2) antigen" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0004003 a rdfs:Class ;
  rdfs:label "Pseudorabies recombinant vector vaccine encoding gp50 protein" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000750 .

obo:VO_0002288 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus, Live Canarypox Vector Vaccine-Tetanus Toxoid (USDA: 48W9.R0)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002431 , obo:VO_0007748 .

obo:VO_0002552 a rdfs:Class ;
  rdfs:label "obsolete aroA from Bordetella bronchiseptica" ;
  rdfs:comment "Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract" .

obo:VO_0015980 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3" ;
  rdfs:subClassOf obo:VO_0003264 .

obo:VO_0000858 a rdfs:Class ;
  rdfs:label "serologic correlated profile of immune protection" ;
  rdfs:comment "Correlated profile of immune protection that is reflected by serologic antibody levels." ;
  rdfs:subClassOf obo:VO_0000857 .

obo:VO_0001625 a rdfs:Class ;
  rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.18)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0001716 a rdfs:Class ;
  rdfs:label "Newcastle Disease Killed Virus Vaccine (USDA: 1705.10)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001222 , obo:VO_0007748 .

obo:VO_0005802 a rdfs:Class ;
  rdfs:label "Giardia lamblia bivalent DNA vaccine encoding a1-giardin and CWP2" ;
  rdfs:comment "A Live attenuated vaccine encoding a1-giardin and CWP2 that immunizes against Giardi lamblia trophozoite." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001083 .

obo:VO_0004768 a rdfs:Class ;
  rdfs:label "rORFV-CSFV-E2 vaccine" ;
  rdfs:subClassOf obo:VO_0001012 .

obo:VO_0005062 a rdfs:Class ;
  rdfs:label "pcDNA3.1/V5-His-TOPO DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1/V5-His-TOPO.  This plasmid is 5523 base pairs in length and contains a CMV promoter and ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002976 a rdfs:Class ;
  rdfs:label "human metapneumovirus G protein mutant vaccine" ;
  rdfs:comment "A G mutant is attenuated in African green monkeys and induces protection from challenge with wild type HMPV" ;
  rdfs:subClassOf obo:VO_0002511 .

obo:VO_0020416 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 1" ;
  rdfs:subClassOf obo:VO_0020391 , obo:VO_0020426 .

obo:VO_0016470 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Veron" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0004368 a rdfs:Class ;
  rdfs:label "Herpes simplex virus DNA vaccine gB-DNA encoding gB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0015929 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [H-B-Vax II] Box of 10" ;
  rdfs:subClassOf obo:VO_0015634 , obo:VO_0016034 .

obo:VO_0000765 a rdfs:Class ;
  rdfs:label "Bordetella pertussis vaccine" ;
  rdfs:comment "A bacterial vaccine that prevents against Bordetella pertussis infection that causes pertussis or whooping cough." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000587 .

obo:VO_0000868 a rdfs:Class ;
  rdfs:label "Vaxigrip vaccine" ;
  rdfs:comment "Vaxigrip is an Influenza virus vaccine that is manufactured by 'Sanofi Pasteur Limited." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0001176 , obo:VO_0010415 .

obo:VO_0017057 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac] by Sanofi" ;
  rdfs:subClassOf obo:VO_0017050 .

obo:VO_0017811 a rdfs:Class ;
  rdfs:label "influenza B virus antigen, Hong Kong 330-2001 / meningococcal group C polysaccharide" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000563 , obo:VO_0003495 .

obo:VO_0003983 a rdfs:Class ;
  rdfs:label "DAPTACEL vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003981 .

obo:VO_0019735 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0020323 .

obo:VO_0003998 a rdfs:Class ;
  rdfs:label "BOOSTRIX vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003995 .

obo:VO_0019211 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0005045 a rdfs:Class ;
  rdfs:label "pND-14 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pND-14.  This plasmid contains a CMV promoter, ampicillin resistance gene, a tissue plasminogen activator leader sequence, a bovine growth hormone terminator, and constitutive transport element from simian retrovirus." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007394 a rdfs:Class ;
  rdfs:label "ICT-121 Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with purified peptides derived from the tumor-associated antigen (TAA) CD133, with potential immunostimulatory and antineoplastic activities. Upon leukapheresis, monocytes are differentiated into DCs and are mixed with the CD133 peptides. Upon intradermal re-administration of the ICT-121 DC vaccine, the DCs present the CD133 peptides to the immune system, which stimulates the immune system to induce a specific cytotoxic T-lymphocyte (CTL) response against CD133-expressing tumor cells and leads to tumor cell lysis. CD133 is overexpressed on various types of cancer cells; its overexpression is correlated with increased resistance to chemotherapy." ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 .

obo:DOID_5041 a rdfs:Class ;
  rdfs:label "esophageal cancer"@en ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the esophagus."@en ;
  rdfs:subClassOf obo:DOID_3119 .

obo:VO_0004440 a rdfs:Class ;
  rdfs:label "Melanoma DNA vaccine gp75 DNA encoding melanosomal membrane glycoproteins, gp75 Vaccine" ;
  rdfs:comment "Gene name: HUMGP 75" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0020528 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC] by Mylan" ;
  rdfs:subClassOf obo:VO_0020525 .

obo:VO_0010031 a rdfs:Class ;
  rdfs:label "Neospora caninum GRA2" ;
  rdfs:comment "A GRA2 protein that is part of Neospora caninum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0002842 a rdfs:Class ;
  rdfs:label "Francisella tularensis FTL0552 mutant vaccine" ;
  rdfs:comment "A FTL0552 mutant in Francisella tularensis was attenuated and provided partial protection in mice against challenge with a lethal dose of the virulent SchuS4 strain when compared to naive mice" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0000590 a rdfs:Class ;
  rdfs:label "vaccine preparation" ;
  rdfs:comment "vaccine preparation is a manufacturing process to produce a vaccine." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0000828 a rdfs:Class ;
  rdfs:label "Yersinia EV76 vaccine" ;
  rdfs:comment "A Yersinia pestis vaccine that is a pigmentation negative mutant of Y. pestis derived from a fully virulent strain." ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0001610 a rdfs:Class ;
  rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0015616 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [H-B-Vax II]" ;
  rdfs:subClassOf obo:VO_0003427 , obo:VO_0015568 .

obo:VO_0000240 a rdfs:Class ;
  rdfs:label "hypersensitity to gelatin" ;
  rdfs:subClassOf obo:VO_0000207 .

obo:VO_0000159 a rdfs:Class ;
  rdfs:label "live attenuated vaccine preparation by serial passages in vitro" ;
  rdfs:comment "A live attenuated vaccine prepraration process that is performed by serial passages in vitro for pathogen attenuation." ;
  rdfs:subClassOf obo:VO_0000718 .

obo:VO_0002749 a rdfs:Class ;
  rdfs:label "E1 from Western equine encephalomyelitis virus" ;
  rdfs:comment "A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001449 .

obo:VO_0015496 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0005111 a rdfs:Class ;
  rdfs:label "MERS-CoV S vaccine adjuvanted with CpG and Alum" ;
  rdfs:comment "A MERS subunit vaccine that has a combined adjuvant of aluminum hydroxide and CpG oligodeoxynucleotides." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0001493 a rdfs:Class ;
  rdfs:label "Mink enteritis virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Mink enteritis virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000389 .

obo:VO_0010143 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, 50 mcg/0.5 mL dose" ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0001086 a rdfs:Class ;
  rdfs:label "complex adenovirus vaccine vector" ;
  rdfs:comment "an adenovirus vaccine vector that uses a complex adenovirus as the vector strain." ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0016550 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015985 .

obo:OPL_0000089 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum ookinete" ;
  rdfs:comment "A Plasmodium falciparum that is a 'banana-shaped' form and originates from the round zygote. The ookinete is found in the midgut of a mosquito vector and traverses the midgut wall of a mosquito vector." ;
  rdfs:subClassOf obo:NCBITaxon_5833 , obo:OPL_0000274 .

obo:VO_0001748 a rdfs:Class ;
  rdfs:label "Distemper Live Canarypox Vector Vaccine (USDA: 1471.R0)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012178 .

obo:VO_0016060 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 3" ;
  rdfs:subClassOf obo:VO_0003420 .

obo:VO_0005097 a rdfs:Class ;
  rdfs:label "Soberana 02 vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine developed by Finlay Vaccine Institute (IFV)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0004698 a rdfs:Class ;
  rdfs:label "PrV-HA (swine-origin H1N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0010239 a rdfs:Class ;
  rdfs:label "sacrifice process variable" ;
  rdfs:comment "A variable representing the planned process used for the sacrifice" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0015310 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015306 .

obo:VO_0005185 a rdfs:Class ;
  rdfs:label "mRNA-1283 vaccine" ;
  rdfs:comment "A SARS-CoV-2 refrigerator-stable mRNA vaccine by Moderna that encodes for the portions of the SARS-CoV-2 spike protein critical for neutralization, specifically the Receptor Binding Domain (RBD) and N-terminal Domain (NTD)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0017394 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Adt Vaccine]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0018791 .

obo:VO_0011192 a rdfs:Class ;
  rdfs:label "Ply" ;
  rdfs:comment "The protective effects a pneumolysin mutant (DeltaA146 Ply) against pneumococcal infections in mice was evaluated. Vaccinated mice were challenged with pneumococcal strain D39 at 1,500 times the LD50 (1.5 x 105 CFU) and the vaccinated mice survived significantly longer than control mice after challenge [PubMed: 20038538]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0016098 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015993 .

obo:NCBITaxon_36855 a rdfs:Class ;
  rdfs:label "Brucella canis" ;
  rdfs:subClassOf obo:NCBITaxon_234 .

obo:VO_0018052 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018143 .

obo:VO_0016993 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 5 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016992 .

obo:VO_0003091 a rdfs:Class ;
  rdfs:label "Fluogen vaccine" ;
  rdfs:comment "Influenza virus vaccine is used to prevent infection caused by influenza virus types A and B." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0002497 , obo:VO_0010415 .

obo:VO_0000276 a rdfs:Class ;
  rdfs:label "pJW4303 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000772 a rdfs:Class ;
  rdfs:label "Streptococcal vaccine" ;
  rdfs:comment "Vaccine that protects against streptococcal infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003555 .

obo:VO_0000105 a rdfs:Class ;
  rdfs:label "vaccine T cell epitope" ;
  rdfs:subClassOf obo:VO_0000811 .

obo:VO_0018257 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML [Rabivac]" ;
  rdfs:subClassOf obo:VO_0003107 , obo:VO_0003863 .

obo:VO_0017907 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine Injectable Suspension [Meningitec]" ;
  rdfs:subClassOf obo:VO_0017847 , obo:VO_0017933 .

obo:VO_0019715 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2015-2016]" ;
  rdfs:subClassOf obo:VO_0010427 , obo:VO_0015080 , obo:VO_0019714 .

obo:VO_0007720 a rdfs:Class ;
  rdfs:label "PD-L1 peptide vaccine" ;
  rdfs:comment "A cancer vaccine composed of a peptide derived from the tumor-associated antigen (TAA) and immune checkpoint molecule programmed cell death-1 ligand 1 (PD-L1) combined with the immunoadjuvant montanide ISA-51, with potential immunomodulating and antineoplastic activities. Vaccination with PD-L1 peptide vaccine may activate the immune system to induce an immune response against PD-L1-expressing cells. This may increase and restore the proliferation and activation of various immune cells, including cytotoxic T-lymphocytes (CTLs), and may eradicate PD-L1-expressing tumor cells. The vaccines aims to stimulate PD-L1 specific T-cells, hence eliminating both PD-L1 positive tumor cells as well as PD-L1 positive immunosuppressive and antigen presenting cells in the tumor microenvironment. It has been used in clinical trials for patients with multiple melanoma." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0003437 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003435 .

obo:VO_0003224 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 19F vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0000706 a rdfs:Class ;
  rdfs:label "vaccine trial regulation" ;
  rdfs:comment "A vaccine regulation process for vaccine clinical trials." ;
  rdfs:subClassOf obo:VO_0000683 .

obo:VO_0017491 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017489 , obo:VO_0017497 .

obo:VO_0016428 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0005073 a rdfs:Class ;
  rdfs:label "pGT146-mIL-12 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pGT146-mIL-12." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016137 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015885 .

obo:VO_0020747 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 4000000 ORGANISMS/ML" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017681 .

obo:VO_0015161 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by MZG" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0019659 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0011259 a rdfs:Class ;
  rdfs:label "NS1 (non-structural protein 1)" ;
  rdfs:comment "Protection from lethal viral infection has been achieved with passively administered monoclonal antibody specific for flavivirus glycoprotein NS1 [PubMed: 1736531]. Immunization of monkeys with yellow fever virus-specified nonstructural protein NS1 resulted in protection against fatal hepatitis as well as marked reduction in the magnitude of viremia after subcutaneous challenge with yellow fever virus [PubMed: 3783816]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010791 .

obo:VO_0017229 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 , obo:VO_0017227 .

obo:VO_0000982 a rdfs:Class ;
  rdfs:label "FluMist Quadrivalent vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0001178 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0012368 a rdfs:Class ;
  rdfs:label "ESAT-6" ;
  rdfs:comment "In a prophylactic vaccine model, immunization with the Mycobacterium tuberculosis protein ESAT-6 with LANAC adjuvant elicited significant protective immunity against aerosol challenge with virulent M. tuberculosis [PubMed: 16751377]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0007738 a rdfs:Class ;
  rdfs:label "TriAd cancer vaccine" ;
  rdfs:comment "A cancer vaccine of 3 adenoviral vaccines (ETBX-011, ETBX-051 & ETBX-061). ETBX-011 uses a replication-defective, E1- and E2b-deleted oncolytic adenoviral serotype 5 (Ad5) encoding an epitope of human carcinoembryonic antigen (CEA). ETBX-051 is composed of a replication-defective, serotype 5 adenovirus (Ad5) with the viral genes early 1 (E1), early 2b (E2b), and early 3 (E3) deleted, and the human transcription factor brachyury encoded. ETBX-061 composed of a replication-defective, serotype 5 adenovirus (Ad5) with the viral genes early 1 (E1), early 2b (E2b), and early 3 (E3) deleted, and the human glycoprotein mucin 1 (MUC1) encoded. The three of these vaccines act against tumor associated antigens and have potential immunostimulating and antineoplastic activities. The TriAd vaccine can be used in combination with Anti-PD-L1/TGF-beta trap (M7824) and Anktiva (N-803) to shrink previously untreated head and neck tumors before surgery or stop the tumors from coming back after all treatment." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0001597 a rdfs:Class ;
  rdfs:label "avian influenza H7N3 Subtype, Killed Virus Vaccine (USDA: 1057.H7)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:OPL_0000093 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum hepatic schizont stage" ;
  rdfs:comment "A hepatic schizont stage in the lifecycle of Plasmodium falciparum that occurs in the infected hepatocytes of a human host." ;
  rdfs:subClassOf obo:OPL_0000059 , obo:OPL_0000158 , obo:OPL_0000299 .

obo:VO_0020430 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0020472 .

obo:VO_0017147 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0017129 , obo:VO_0017607 .

obo:NCBITaxon_2901879 a rdfs:Class ;
  rdfs:label "Severe acute respiratory syndrome coronavirus" ;
  rdfs:subClassOf obo:NCBITaxon_694009 .

obo:VO_0004210 a rdfs:Class ;
  rdfs:label "Ovine Ecthyma live virus vaccine by Texas Agricultural Experiment Station" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000503 , obo:VO_0001220 , obo:VO_0001460 .

obo:VO_0001998 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:VO_0018167 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution [Priorix]" ;
  rdfs:subClassOf obo:VO_0018165 , obo:VO_0018166 , obo:VO_0018182 .

obo:VO_0007354 a rdfs:Class ;
  rdfs:label "Carcinoembryonic Antigen RNA-pulsed DC Cancer Vaccine" ;
  rdfs:comment "A vaccine comprised of autologous dendritic cells pulsed with mRNA-encoded Carcinoembryonic Antigen (CEA) targeting tumor cells expressing CEA. " ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:PATO_0000001 a rdfs:Class ;
  rdfs:label "quality" ;
  rdfs:comment "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:VO_0017102 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017570 .

obo:VO_0019611 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluarix Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020320 .

obo:VO_0002755 a rdfs:Class ;
  rdfs:label "cen1 from Leishmania donovani" ;
  rdfs:comment "A cen1 mutant is attenuated in mice and hamsters and induces significant protection from challenge with wild type L. donovani" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001450 .

obo:VO_0003664 a rdfs:Class ;
  rdfs:label "influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010316 , obo:VO_0010415 .

obo:VO_0018606 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 698000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004820 .

obo:VO_0018669 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 1000 MG Oral Suspension" ;
  rdfs:subClassOf obo:VO_0018667 , obo:VO_0020187 .

obo:VO_0004810 a rdfs:Class ;
  rdfs:label "2011-2012 trivalent inactivated vaccine (A/California/7/09 (H1N1), A/Perth /16/2009 (H3N2), and B/Brisbane/60/2008)" ;
  rdfs:comment "2010-2011 trivalent seasonal inactivated influenza vaccine 2010 consisting of Influenza A virus (A/California/7/2009(H1N1)), Influenza A virus (A/Texas/50/2012(H3N2)), Influenza B virus (B/Brisbane/60/2008)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0018246 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 12500 UNT / Rubella virus vaccine 1000 UNT" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0002319 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine-Bordetella Bronchiseptica-Clostridium Perfringens Type C-Erysipelothrix Rhusiopathiae-Escherichia Coli-Pasteurella Multocida Bacterin-Toxoid (USDA: 49T9.21)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000619 , obo:VO_0001220 , obo:VO_0002468 , obo:VO_0007748 .

obo:VO_0020542 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Afluria] by bioCSL" ;
  rdfs:subClassOf obo:VO_0020539 .

obo:VO_0019203 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0015256 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Havpur]" ;
  rdfs:subClassOf obo:VO_0015251 , obo:VO_0015252 .

obo:VO_0001759 a rdfs:Class ;
  rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.29)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012180 .

obo:VO_0004757 a rdfs:Class ;
  rdfs:label "rBCG-Ag85A/Ag85B vaccine" ;
  rdfs:subClassOf obo:VO_0003130 .

obo:VO_0000213 a rdfs:Class ;
  rdfs:label "hypersensitivity to chicken product" ;
  rdfs:subClassOf obo:VO_0000207 .

obo:VO_0020307 a rdfs:Class ;
  rdfs:label "Agriflu 2010-2011 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0001126 , obo:VO_0010426 .

obo:VO_0016734 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016720 .

obo:VO_0010200 a rdfs:Class ;
  rdfs:label "Japanese Encephalitis vaccine for intramuscular administration" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010440 .

obo:VO_0021029 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe [Zostavax]" ;
  rdfs:subClassOf obo:VO_0021028 , obo:VO_0021048 .

obo:VO_0003051 a rdfs:Class ;
  rdfs:label "percutaneous route" ;
  rdfs:comment "epicutaneous (application onto the skin)" ;
  rdfs:subClassOf obo:VO_0000574 .

obo:OAE_0000055 a rdfs:Class ;
  rdfs:label "contraindication" ;
  rdfs:comment "A contraindication is a disposition that increases the risk of harm involved in using a particular drug, carrying out a medical procedure, or engaging in a particular activity such that the risk of harm exceeds a threshold. An contraindication serves as a reason to withhold a certain medical treatment." ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:VO_0001579 a rdfs:Class ;
  rdfs:label "Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1841.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0000990 , obo:VO_0001220 .

obo:VO_0019309 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML Prefilled Syringe [Fluzone High-Dose 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019308 , obo:VO_0020484 .

obo:VO_0005033 a rdfs:Class ;
  rdfs:label "pGT36 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pGT36.  This plasmid is a derivative of pcDNA3 and contains a CMV promoter and a kanamycin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007012 a rdfs:Class ;
  rdfs:label "Recombinant Adenovirus-Cre Recombinase Vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0016112 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015872 .

obo:VO_0004357 a rdfs:Class ;
  rdfs:label "Hepatitis B DNA vaccine pS encoding major envelope proteins" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000644 .

obo:VO_0019355 a rdfs:Class ;
  rdfs:label "0.7 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0016018 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 50" ;
  rdfs:subClassOf obo:VO_0003425 .

obo:VO_0001234 a rdfs:Class ;
  rdfs:label "protozoan vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a protozoan vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0001798 a rdfs:Class ;
  rdfs:label "Porcine Circovirus Type 2, Killed Virus Vaccine (USDA: 19K5.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001524 , obo:VO_0007748 .

obo:VO_0021109 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0019760 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML [Flulaval Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020344 .

obo:DOID_5295 a rdfs:Class ;
  rdfs:label "intestinal disease"@en ;
  rdfs:comment "A gastrointestinal system disease that is located_in the intestine."@en ;
  rdfs:subClassOf obo:DOID_77 .

obo:VO_0011455 a rdfs:Class ;
  rdfs:label "Dengue vaccine using Vaccinia virus expressing M protein" ;
  rdfs:subClassOf obo:VO_0000725 .

obo:VO_0011501 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus DNA vaccine pUJENS3" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000665 .

obo:VO_0007387 a rdfs:Class ;
  rdfs:label "Glioma-associated Peptide-loaded Dendritic Cell Vaccine SL-701" ;
  rdfs:comment "A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various, synthetic glioma-associated antigen (GAA) peptides, with potential antineoplastic activity. Upon subcutaneous administration, the glioma-associated peptide-loaded DC vaccine SL-701 exposes the immune system to various GAA peptides. This may stimulate both anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against the GAA-expressing glioma cells, which may result in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0007419 a rdfs:Class ;
  rdfs:label "MUC-1 peptide vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a synthetic peptide derived from the mucin 1 (MUC1) antigen with potential antineoplastic activity. Upon administration, MUC1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the MUC1 antigen, resulting in decreased tumor growth. Overexpressed on many tumor cells, MUC1 antigen, a mammary-type apomucin, is a high-molecular-weight transmembrane glycoprotein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0015709 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 3" ;
  rdfs:subClassOf obo:VO_0015570 , obo:VO_0015792 .

obo:VO_0002380 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002381 .

obo:VO_0020298 a rdfs:Class ;
  rdfs:label "Afluria 2010-2011 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000006 , obo:VO_0000578 , obo:VO_0010426 .

obo:VO_0015669 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015492 .

obo:NCBITaxon_119088 a rdfs:Class ;
  rdfs:label "Enoplea" ;
  rdfs:subClassOf obo:NCBITaxon_1206794 .

obo:VO_0018519 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:VO_0004554 a rdfs:Class ;
  rdfs:label "Chlamydia trachomatis DNA vaccine pWRG7079::MOMP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001207 .

obo:VO_0004777 a rdfs:Class ;
  rdfs:label "ALVAC-JEV vaccine" ;
  rdfs:subClassOf obo:VO_0000665 .

obo:VO_0020534 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / influenza B virus antigen 0.02 MG/ML Injectable Solution [HibTITER]" ;
  rdfs:subClassOf obo:VO_0020533 , obo:VO_0020828 .

obo:VO_0004259 a rdfs:Class ;
  rdfs:label "HIV-2 DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0019801 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0003708 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0000983 , obo:VO_0010431 .

obo:VO_0015210 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015208 .

obo:VO_0000939 a rdfs:Class ;
  rdfs:label "yeast extract cell culture residual in vaccine" ;
  rdfs:comment "a cell culture residual in vaccine that is from yeast extract." ;
  rdfs:subClassOf obo:VO_0000856 .

obo:VO_0015542 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Suspension [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0003416 .

obo:VO_0015245 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015243 .

obo:VO_0007663 a rdfs:Class ;
  rdfs:label "genetically engineered allogeneic prostate carinoma cells secreting interleukin-3 and interferon gamma vaccine" ;
  rdfs:comment "A cancer vaccine made with HLA class I-matched allogeneic human prostate carcinoma cells that are genetically engineered to secrete interleukin-2 and interferon gamma for patients with prostate carcinoma. Interleukin-2 may stimulate a person's white blood cells including natural killer cells to kill prostate cancer cells. Interferon gamma may interfere with the growth of the cancer cells. Combining interferon gamma with interleukin-2 may be a more effective treatment for prostate cancer." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0002573 a rdfs:Class ;
  rdfs:label "vjbR from B. melitensis" ;
  rdfs:comment "The deletion of vjbR gene in Brucella melitensis strain 16M made a live attenuated vaccine and provided significance protection against mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001400 .

obo:VO_0001097 a rdfs:Class ;
  rdfs:label "RECOMBITEK rDistemper vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000649 , obo:VO_0012178 .

obo:VO_0003864 a rdfs:Class ;
  rdfs:label "RabAvert Injectable Product" ;
  rdfs:subClassOf obo:VO_0000094 .

obo:OGG_2060083332 a rdfs:Class ;
  rdfs:label "protein-coding gene of Mycobacterium tuberculosis H37Rv" ;
  rdfs:comment "A gene of Mycobacterium tuberculosis H37Rv that has a protein-coding gene disposition" ;
  rdfs:subClassOf obo:OGG_2000083332 .

obo:VO_0004658 a rdfs:Class ;
  rdfs:label "rDEV-us78HA vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0007220 a rdfs:Class ;
  rdfs:label "allogeneic dendritic cell vaccine COMBIG-DC" ;
  rdfs:comment "A cancer vaccine consisting of allogeneic, immortalized dendritic cells (DCs) loaded with tumor specific antigens and activated, with potential immunostimulatory and antineoplastic activities. Upon intratumoral administration of the allogeneic dendritic cell vaccine COMBIG-DC, these activated DCs attract natural killer (NK) cells, induce an anti-inflammatory response leading to the induction of NK-cell-mediated tumor cell death. Upon release of tumor associated antigens (TAAs) from the lysed tumor cells, these antigens are taken up by antigen presenting cells which activate the immune system to elicit a potent cytotoxic T-cell (CTL) response against the TAAs, resulting in the death of TAAs-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0001430 a rdfs:Class ;
  rdfs:label "Classical swine fever virus gene" ;
  rdfs:comment "A viral gene that is from Classical swine fever virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0015485 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015489 .

obo:VO_0001463 a rdfs:Class ;
  rdfs:label "obsolete Fowlpox virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Fowlpox virus infection" .

obo:VO_0020588 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] Box of 10" ;
  rdfs:subClassOf obo:VO_0020587 , obo:VO_0020603 , obo:VO_0020877 .

obo:VO_0019119 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0006036 a rdfs:Class ;
  rdfs:label "Meningococcal MCV4 unspecified conjugate formulation(groups A C Y and W-135)" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010444 .

obo:OPL_0000175 a rdfs:Class ;
  rdfs:label "Trypanosoma brucei trypomastigote stage" ;
  rdfs:comment "A trypomastigote stage in the Trypanosoma brucei lifecycle that occurs in the vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000033 , obo:OPL_0000048 .

obo:VO_0015508 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML [H-B-Vax II]" ;
  rdfs:subClassOf obo:VO_0003423 .

obo:VO_0018152 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 100" ;
  rdfs:subClassOf obo:VO_0018150 , obo:VO_0018156 .

obo:VO_0005253 a rdfs:Class ;
  rdfs:label "Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated virus vaccine by Kocak Farma" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005201 .

obo:VO_0017442 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.08 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017440 , obo:VO_0017445 .

obo:VO_0017918 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / meningococcal polysaccharide vaccine group W-135 / meningococcal polysaccharide vaccine group Y Injectable Solution [Menquadfi]" ;
  rdfs:subClassOf obo:VO_0017819 .

obo:VO_0005435 a rdfs:Class ;
  rdfs:label "SARS-COV-2 COVID-19 mRNA, bivalent, original/Omicron BA.1, Non-US Vaccine Product (Comirnaty Bivalent), Pfizer-BioNTech" ;
  rdfs:comment "A Comirnaty COVID-19 mRNA vaccine produced by Pfizer-BioNTech,which is a bivalent vaccine that is effective against the original strain of COVID-19 as well as the Omicron BA.1 variant.A non-US vaccine product." ;
  rdfs:subClassOf obo:VO_0004987 .

obo:VO_0018058 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 20" ;
  rdfs:subClassOf obo:VO_0018053 , obo:VO_0018077 , obo:VO_0018147 .

obo:VO_0003483 a rdfs:Class ;
  rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010304 , obo:VO_0010415 .

obo:VO_0016071 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015868 .

obo:VO_0003359 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine Prefilled Syringe [Bexsero]" ;
  rdfs:subClassOf obo:VO_0004851 .

obo:VO_0017329 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000738 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0010415 , obo:VO_0017808 .

obo:VO_0005145 a rdfs:Class ;
  rdfs:label "MERS GLS-5300 vaccine" ;
  rdfs:comment "A MERS DNA Vaccine that is made of the plasmid pGX9109 expressing MERS S protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0004900 .

obo:VO_0016154 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0018442 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 10" ;
  rdfs:subClassOf obo:VO_0018423 .

obo:VO_0010770 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:VO_0016853 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016801 .

obo:VO_0020476 a rdfs:Class ;
  rdfs:label "Fluvirin 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000046 , obo:VO_0010416 .

obo:VO_0000025 a rdfs:Class ;
  rdfs:label "Brucella vaccine" ;
  rdfs:comment "A vaccine that protects against Brucella that causes brucellosis in animals and humans." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003550 .

obo:VO_0019510 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010325 , obo:VO_0010438 .

obo:VO_0018268 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT" ;
  rdfs:subClassOf obo:VO_0003862 .

obo:VO_0015319 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Prefilled Syringe [Epaxal]" ;
  rdfs:subClassOf obo:VO_0003432 , obo:VO_0010713 .

obo:VO_0001482 a rdfs:Class ;
  rdfs:label "obsolete bovine herpesvirus 1 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Bovine herpesvirus 1 infection" .

obo:VO_0003681 a rdfs:Class ;
  rdfs:label "Fluvirin 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000046 , obo:VO_0010432 .

obo:VO_0010086 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii CDPK6" ;
  rdfs:comment "A CDPK6 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0020108 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine / L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine / L1 protein, human papillomavirus type 6 vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018798 .

obo:VO_0017760 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 160 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003196 .

obo:VO_0007430 a rdfs:Class ;
  rdfs:label "Human Papilloma Virus L1 Virus-Like Particle V504 Vaccine" ;
  rdfs:comment "A vaccine formulation consisting of several types of human papillomavirus (HPV)-derived noninfectious virus-like particles (VLPs) with potential immunoprophylactic activity. Upon administration, HPV L1 VLP vaccine V504 may generate humoral immunity against various HPV L. major capsid proteins, thereby preventing cervical infection upon exposure to the associated HPV types. VLPs are composed of self-assembling L. major capsid proteins or functional L. major capsid protein derivatives." ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0005488 , obo:VO_0007657 .

obo:VO_0011232 a rdfs:Class ;
  rdfs:label "RABVgp1 nucleoprotein N" ;
  rdfs:comment "Mice vaccinated intraperitoneally (i.p.) with 10^7 p.f.u. of a vaccinia virus recombinant expressing either the glycoprotein (rVac-G) or nucleoprotein (rVac-N) of rabies virus 3 weeks before challenge were protected against peripheral lethal infection [PubMed: 8207400]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010788 .

obo:VO_0003080 a rdfs:Class ;
  rdfs:label "Nimenrix vaccine" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000195 , obo:VO_0010444 .

obo:VO_0003119 a rdfs:Class ;
  rdfs:label "Hib-Imune vaccine" ;
  rdfs:comment "Active immunization against Haemophilius influenzae type b in recommended routinely for children at 24 months of age and for children at 15 months of age enrolled in child care facilities." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000627 .

obo:VO_0011113 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/WSN/1933(H1N1))" ;
  rdfs:comment "A nonpathogenic vector of the cytoplasmic domain of the VSV G protein and expressing influenza virus HA (derived from Influenza A virus (A/WSN/1933(H1N1))) provides complete protection from lethal influenza virus challenge after intranasal administration. A second vector with VSV G deleted and expressing HA (DeltaG-HA) is also protective and nonpathogenic and has the advantage of not inducing neutralizing antibodies to the vector itself [PubMed: 10196265]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0018402 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 14 vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003219 .

obo:VO_0001643 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.13)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0019558 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flucelvax Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020332 .

obo:VO_0020175 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003863 .

obo:VO_0015116 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015111 .

obo:VO_0007651 a rdfs:Class ;
  rdfs:label "RIPO(H3.3) vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0019999 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0003040 a rdfs:Class ;
  rdfs:label "Tween 20 vaccine stabilizer" ;
  rdfs:comment "a polysorbate 20 vaccine stabilizer that is Tween 20." ;
  rdfs:subClassOf obo:VO_0000929 .

obo:VO_0005105 a rdfs:Class ;
  rdfs:label "SARS CTLA4-S DNA vaccine" ;
  rdfs:comment "A SARS DNA vaccine that is made from  CTLA4HingeSARS800 DNA with SARS-CoV S protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012183 .

obo:VO_0002251 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.45)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002422 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0018767 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain Injectable Suspension [Stamaril]" ;
  rdfs:subClassOf obo:VO_0018809 .

obo:VO_0001983 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002360 .

obo:VO_0003503 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0003502 .

obo:VO_0010358 a rdfs:Class ;
  rdfs:label "Refrigerator-Stable Formulation - ProQuad vaccine" ;
  rdfs:subClassOf obo:VO_0000091 .

obo:VO_0000279 a rdfs:Class ;
  rdfs:label "pK3 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003748 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2017-2018 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003746 .

obo:VO_0004188 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi DbpA and OspA Protein vaccine" ;
  rdfs:subClassOf obo:VO_0000764 .

obo:VO_0020517 a rdfs:Class ;
  rdfs:label "0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML Nasal Spray [FluMist Quadrivalent]" ;
  rdfs:subClassOf obo:VO_0020516 , obo:VO_0020947 .

obo:VO_0005452 a rdfs:Class ;
  rdfs:label "licensed human tetanus immune globulin passive vaccine" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0015582 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015536 , obo:VO_0015597 .

obo:VO_0020003 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML [Fluzone High-Dose 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020485 .

obo:VO_0000621 a rdfs:Class ;
  rdfs:label "laboratory animal model of vaccine research" ;
  rdfs:comment "Animal model of vaccine research is a role played by some organism (e.g., mouse) that is used for vaccine research in the laboratory." ;
  rdfs:subClassOf obo:VO_0000616 .

obo:VO_0017333 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injection [Act-HIB DTP]" ;
  rdfs:subClassOf obo:VO_0017332 .

obo:VO_0004788 a rdfs:Class ;
  rdfs:label "rCPV-BTV-Cpox vaccine" ;
  rdfs:subClassOf obo:VO_0001515 .

obo:VO_0018736 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 2000000000 ORGANISMS Delayed Release Oral Capsule [Vivotif Berna] Box of 3" ;
  rdfs:subClassOf obo:VO_0018735 , obo:VO_0018738 .

obo:VO_0003296 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003338 .

obo:VO_0015805 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 3" ;
  rdfs:subClassOf obo:VO_0015493 .

obo:VO_0017707 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017756 .

obo:VO_0007348 a rdfs:Class ;
  rdfs:label "Bcl-Xl_42-CAF09b vaccine" ;
  rdfs:comment "A cancer vaccine made up of Bcl-xl_42 and the adjuvant CAF09b for patients with hormone-sensitive Prostate Cancer (PC) and lymph node metastases. B-cell lymphoma extra large protein (Bcl-xl) protein plays a vital role in the cancer cell's ability to avoid programmed cell death (apoptosis) and is upregulated in a variety of cancerous diseases, Bcl-xl_42 is a peptide fragment of the full protein and can lead to the death of cancer cells. CAF09b improves the activation of the immune system. " ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0020733 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Suspension [ImmuCyst] by Sanofi" ;
  rdfs:subClassOf obo:VO_0020730 .

obo:VO_0004521 a rdfs:Class ;
  rdfs:label "Herpes Simplex Virus 2 DNA Vaccine Vaxfectin-gD2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0018599 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 772000 PFU/ML" ;
  rdfs:subClassOf obo:VO_0004825 .

obo:VO_0015741 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015495 , obo:VO_0015806 .

obo:VO_0001507 a rdfs:Class ;
  rdfs:label "Bovine Respiratory Syncytial Virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Bovine Respiratory Syncytial Virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0001271 a rdfs:Class ;
  rdfs:label "Montanide vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant developed by Montanide." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0016101 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015993 .

obo:VO_0018617 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000665 , obo:VO_0010440 .

obo:VO_0002958 a rdfs:Class ;
  rdfs:label "Feline herpesvirus 1 UL23 mutant vaccine" ;
  rdfs:comment "A thymidine kinase-deficient mutant (C7301dlTK) is attenuated in cats and induced significant protection from wild type FHV-1 4 weeks after vaccination" ;
  rdfs:subClassOf obo:VO_0001487 .

obo:VO_0002079 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass & Ark Types, Killed Virus Vaccine (USDA: 12M5.41)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0019684 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003627 .

obo:VO_0000206 a rdfs:Class ;
  rdfs:label "licensed pig vaccine" ;
  rdfs:subClassOf obo:VO_0000363 , obo:VO_0001474 .

obo:VO_0011221 a rdfs:Class ;
  rdfs:label "MSP8" ;
  rdfs:comment "Immunization with Plasmodium yoelii merozoite surface protein (PyMSP)-8 protects mice from lethal malaria but does not prevent infection [PubMed: 18097046]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015474 .

obo:VO_0003520 a rdfs:Class ;
  rdfs:label "human influenza B-like virus vaccine" ;
  rdfs:subClassOf obo:VO_0003495 , obo:VO_0004914 .

obo:VO_0015842 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] by Sanofi" ;
  rdfs:subClassOf obo:VO_0015637 .

obo:VO_0003148 a rdfs:Class ;
  rdfs:label "LIPO-5 vaccine" ;
  rdfs:comment "LIPO-5 is a therapeutic HIV vaccine made up of lipopeptides, Study Names: VRI02/ANRS 149 LIGHT; NCT01492985" ;
  rdfs:subClassOf obo:VO_0000295 , obo:VO_0000550 .

obo:VO_0007532 a rdfs:Class ;
  rdfs:label "hTERT-LAMP mRNA-loaded autologous dendritic cell vaccine GRNVAC1" ;
  rdfs:comment "A cancer vaccine containing dendritic cells (DCs) that are transfected with messenger RNA (mRNA) encoding human telomerase reverse transcriptase (hTERT) and LAMP. " ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0002064 a rdfs:Class ;
  rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.T0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002385 , obo:VO_0007748 .

obo:VO_0002151 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1761.14)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0005336 a rdfs:Class ;
  rdfs:label "AAV5-RBD-S vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine by Biocad" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0020363 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Oral Capsule [Typhoral L]" ;
  rdfs:subClassOf obo:VO_0020372 .

obo:VO_0019174 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.07 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0019493 .

obo:VO_0005022 a rdfs:Class ;
  rdfs:label "pTPA-PA63 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pTPA-PA63." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0010217 a rdfs:Class ;
  rdfs:label "rotavirus, live, pentavalent vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010449 .

obo:VO_0019156 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.006 MG/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Vaxelis]" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000744 , obo:VO_0000746 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0002100 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza Modified Live Virus Vaccine (USDA: 13C1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002407 , obo:VO_0007748 .

obo:VO_0003130 a rdfs:Class ;
  rdfs:label "recombinant BCG vaccine" ;
  rdfs:comment "A TB vaccine that uses BCG as vaccine vector." ;
  rdfs:subClassOf obo:VO_0000077 , obo:VO_0000484 , obo:VO_0001217 .

obo:VO_0015221 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015218 .

obo:VO_0016865 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016821 .

obo:VO_0020808 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain Injection [Oncotice Bcg]" ;
  rdfs:subClassOf obo:VO_0019412 .

obo:NCBITaxon_10912 a rdfs:Class ;
  rdfs:label "Rotavirus" ;
  rdfs:subClassOf obo:NCBITaxon_2946186 .

obo:VO_0004224 a rdfs:Class ;
  rdfs:label "Rotavirus Chimeric VP6 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000658 .

obo:NCBITaxon_11128 a rdfs:Class ;
  rdfs:label "Bovine coronavirus" ;
  rdfs:subClassOf obo:NCBITaxon_694002 .

obo:VO_0002548 a rdfs:Class ;
  rdfs:label "vicK from Streptococcus equi" ;
  rdfs:comment "A vicK mutant is attenuated in mice and induced protection from challenge with wild type S. equi" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0002504 .

obo:VO_0001868 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci-Rabies Modified Live & Killed Virus, Modified Live Chlamydia Vaccine (USDA: 1619.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0002438 , obo:VO_0007748 .

obo:VO_0015658 a rdfs:Class ;
  rdfs:label "1 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0015560 , obo:VO_0015600 .

obo:VO_0018847 a rdfs:Class ;
  rdfs:label "oral tablet" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:VO_0018210 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 12500 UNT / Rubella virus vaccine 1000 UNT Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018246 .

obo:VO_0004242 a rdfs:Class ;
  rdfs:label "inactivated HIV-2 vaccine with PMMA" ;
  rdfs:subClassOf obo:VO_0000295 , obo:VO_0000712 .

obo:VO_0019110 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020000 .

obo:VO_0007005 a rdfs:Class ;
  rdfs:label "Recombinant Adenovirus-LacZ Vaccine" ;
  rdfs:comment "Gene name: lacZ" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0003875 a rdfs:Class ;
  rdfs:label "Flublok 2012-2013 Formula Injectable Product" ;
  rdfs:subClassOf obo:VO_0003874 .

obo:VO_0000120 a rdfs:Class ;
  rdfs:label "Vivotif (USA)" ;
  rdfs:subClassOf obo:VO_0003353 .

obo:VO_0015017 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injectable Product" ;
  rdfs:subClassOf obo:VO_0015014 .

obo:VO_0020267 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 2 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020266 .

obo:VO_0000557 a rdfs:Class ;
  rdfs:label "attenuated Mycobacterium bovis strain WAg522 vaccine" ;
  rdfs:subClassOf obo:VO_0000077 , obo:VO_0001217 .

obo:VO_0006065 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free pediatric 25 mcg/0.25 mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0002562 a rdfs:Class ;
  rdfs:label "exsA from B. abortus" ;
  rdfs:comment "Brucella DeltaexsA mutant showed decreased survival in mice compared to the survival of parental strain S2308. This demonstrated that ExsA is critical for full bacterial virulence. The B. abortus exsA deletion mutant was used as a live vaccine candidate. Challenge experiments revealed that the exsA mutant strain induced superior protective immunity in BALB/c mice compared to the protective immunity induced by strain S19 or RB51" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000793 .

obo:VO_0017655 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0016104 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 20 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015994 .

obo:VO_0019614 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluarix Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020323 .

obo:VO_0018756 a rdfs:Class ;
  rdfs:label "Tick-borne encephalitis virus inactivated Injectable Suspension [Ticovac]" ;
  rdfs:subClassOf obo:VO_0018754 .

obo:VO_0016694 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 12.5 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0016901 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.01 MG/ML / Bordetella pertussis 0.008 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Boostrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0016900 , obo:VO_0016902 , obo:VO_0017278 .

obo:VO_0005474 a rdfs:Class ;
  rdfs:label "3M-052-AF vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is a lipid-based nanosuspension of a synthetic TLR7/8 ligand that facilitates adsorption to aluminum oxyhydroxide via the structural properties of the helper lipid employed." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:UBERON_0003408 a rdfs:Class ;
  rdfs:label "gland of digestive tract" ;
  rdfs:comment "A gland that is part of a digestive tract [Automatically generated definition]." ;
  rdfs:subClassOf obo:UBERON_0002530 , obo:UBERON_0013765 .

obo:VO_0010828 a rdfs:Class ;
  rdfs:label "Neospora caninum protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0017666 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Prefilled Syringe [Clostet]" ;
  rdfs:subClassOf obo:VO_0003400 .

obo:VO_0003108 a rdfs:Class ;
  rdfs:label "Genhevac B vaccine" ;
  rdfs:comment "This absorbed recombinant hepatitis B vaccine is indicated for active immunization against hepatitis B virus infection caused by all known subtypes in subjects of any age considered at risk of exposure to the virus." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0010439 .

obo:VO_0003311 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 7F vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003253 .

obo:VO_0016318 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 3 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015933 .

obo:VO_0018796 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000508 , obo:VO_0001214 , obo:VO_0010445 .

obo:VO_0011389 a rdfs:Class ;
  rdfs:label "Rickettsia DNA vaccine encoding OmpB Protein boosted with recombinant OmpB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000484 , obo:VO_0000767 .

obo:VO_0006025 a rdfs:Class ;
  rdfs:label "influenza virus vaccine whole virus" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0018039 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018046 .

obo:OPMI_0000441 a rdfs:Class ;
  rdfs:label "biomarker role"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0019935 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003579 .

obo:VO_0001089 a rdfs:Class ;
  rdfs:label "CDC recommendation of the use of  Influenza A (h1N1) 2009 vaccine" ;
  rdfs:subClassOf obo:IAO_0000001 .

obo:VO_0003781 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003779 .

obo:VO_0019273 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0020322 .

obo:VO_0001143 a rdfs:Class ;
  rdfs:label "Avipox virus vaccine vector" ;
  rdfs:comment "a poxvirus vaccine vector that uses an avipox virus as the vector" ;
  rdfs:subClassOf obo:VO_0000447 .

obo:VO_0003719 a rdfs:Class ;
  rdfs:label "Afluria 2015-2016 Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003716 .

obo:VO_0015564 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [Hevac B]" ;
  rdfs:subClassOf obo:VO_0015489 , obo:VO_0015552 .

obo:VO_0018315 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Injectable Suspension [Tollwut-Impfstoff] by Sanofi" ;
  rdfs:subClassOf obo:VO_0018293 .

obo:VO_0000680 a rdfs:Class ;
  rdfs:label "Shigella flexneri vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000769 .

obo:VO_0001227 a rdfs:Class ;
  rdfs:label "Human betaherpesvirus 5 vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Human herpesvirus 5." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000727 .

obo:VO_0010799 a rdfs:Class ;
  rdfs:label "Porcine circovirus 2 protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0005202 a rdfs:Class ;
  rdfs:label "COVID-19 subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0004908 .

obo:VO_0004105 a rdfs:Class ;
  rdfs:label "Live attenuated vaccine TC-83" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0001499 .

obo:VO_0007151 a rdfs:Class ;
  rdfs:label "PSA-OP Peptide Vaccine" ;
  rdfs:comment "A 30-residue prostate specific antigen (PSA) oligoepitope peptide (OP) vaccine with potential antineoplastic activity. PSA-OP peptide vaccine contains the PSA-1 and PSA-3 HLA-A2 epitopes and the PSA-9 HLA-class I-A3 epitope joined by peptide linker sequences. In an animal model, vaccination with this agent has been shown to elicit a cytotoxic T-lymphocyte immune response." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0018010 a rdfs:Class ;
  rdfs:label "Poliomyelitis Virus Type 1 (Sabin Strain (Ls-C, 2ab)) Live Attenuated Oral Vaccine 1000000 UNT" ;
  rdfs:subClassOf obo:VO_0018009 .

obo:VO_0004607 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae HS93Tox-/pIG-T1K vectored vaccine" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0006104 a rdfs:Class ;
  rdfs:label "S-540956 vaccine adjuvant" ;
  rdfs:comment "An oligonucleotide vaccine adjuvant that is a TLR9-agonistic adjuant containing a CpG oligonucleotide annealed to a complementary strand with an amphiphilic chain unit, acts as a potent cancer vaccine adjuvant by targeting draining lymph nodes." ;
  rdfs:subClassOf obo:VO_0006102 .

obo:VO_0001452 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii gene" ;
  rdfs:comment "A Plasmodium gene that is from Plasmodium yoelii." ;
  rdfs:subClassOf obo:VO_0000171 .

obo:VO_0015148 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015237 .

obo:VO_0003348 a rdfs:Class ;
  rdfs:label "live attenuated vaccine-induced up-regulated gene expression compared to infection with wild type pathogen" ;
  rdfs:comment "A vaccine-induced up-regulation gene expression that occurs in live attenuated vaccine and compared with the host system infected with live wild type virulent strain which is the parent strain of this live attenuated vaccine. " ;
  rdfs:subClassOf obo:VO_0000569 .

obo:VO_0019529 a rdfs:Class ;
  rdfs:label "obsolete hepatitis B surface antigen vaccine 0.04 MG/ML" .

obo:VO_0004752 a rdfs:Class ;
  rdfs:label "rFP-RPV-H/F vaccine" ;
  rdfs:subClassOf obo:VO_0001455 .

obo:VO_0016688 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0020304 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2020-2021 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0001817 , obo:VO_0010424 .

obo:DOID_0060083 a rdfs:Class ;
  rdfs:label "immune system cancer"@en ;
  rdfs:comment "An organ system cancer located_in the immune system that is characterized by uncontrolled cellular proliferation in organs of the immune system."@en ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_2914 .

obo:VO_0003000 a rdfs:Class ;
  rdfs:label "Western equine encephalomyelitis virus PE2/E1 mutant vaccine" ;
  rdfs:comment "A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ;
  rdfs:subClassOf obo:VO_0012188 .

obo:VO_0011039 a rdfs:Class ;
  rdfs:label "PtxE" ;
  rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model. These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:VO_0019214 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019723 .

obo:VO_0003508 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0003507 .

obo:VO_0019547 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003727 , obo:VO_0019544 .

obo:VO_0004177 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding M1 from influenza A virus (A/chicken/Henan/12/2004(H5N1))" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:OPL_0000303 a rdfs:Class ;
  rdfs:label "Plasmodium trophozoite stage" ;
  rdfs:comment "A trophozoite stage in the Plasmodium lifecycle that occurs in a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000057 .

obo:VO_0016551 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015986 .

obo:VO_0003300 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 6 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003299 , obo:VO_0010446 .

obo:VO_0019123 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010423 .

obo:VO_0015698 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [H-B-Vax II] Box of 10" ;
  rdfs:subClassOf obo:VO_0015568 , obo:VO_0015787 .

obo:VO_0010063 a rdfs:Class ;
  rdfs:label "Plasmodium vivax CS" ;
  rdfs:comment "A CS protein that is part of Plasmodium vivax|A PvCS protein that is part of Plasmodium vivax" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015473 .

obo:OPL_0000004 a rdfs:Class ;
  rdfs:label "Triatominae hindgut" ;
  rdfs:comment "A hindgut that is a part of or originated from a Triatominae bug." ;
  rdfs:subClassOf obo:UBERON_0001046 .

obo:VO_0016045 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015670 , obo:VO_0015800 .

obo:VO_0007303 a rdfs:Class ;
  rdfs:label "Autologous Lymphoma Cell/Allogeneic Dendritic Cell Electrofusion Hybrid Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine consisting of hybrid cells created by electrofusing allogeneic dendritic cells (DCs) and autologous lymphoma cells with potential immunostimulating and antitumor activities. Upon administration, autologous lymphoma cell/allogeneic dendritic cell electrofusion hybrid vaccine may stimulate the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against specific autologous lymphoma-associated antigens, resulting in lymphoma cell apoptosis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0019138 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019136 , obo:VO_0020482 .

obo:VO_0017757 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017755 , obo:VO_0017756 , obo:VO_0017772 .

obo:VO_0002469 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0001505 , obo:VO_0002471 .

obo:VO_0010933 a rdfs:Class ;
  rdfs:label "NP Marburgvirus - Ravn" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010769 .

obo:VO_0018482 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0018457 .

obo:IAO_0000032 a rdfs:Class ;
  rdfs:label "scalar measurement datum"@en ;
  rdfs:comment "A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0021080 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.006 MG/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Vaxelis]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0016511 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe Box of 3 by European" ;
  rdfs:subClassOf obo:VO_0016060 .

obo:VO_0017615 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Pediacel] Box of 20" ;
  rdfs:subClassOf obo:VO_0017613 , obo:VO_0017628 .

obo:VO_0015752 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015812 .

obo:VO_0001734 a rdfs:Class ;
  rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.04)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001019 , obo:VO_0007748 .

obo:VO_0004570 a rdfs:Class ;
  rdfs:label "Pseudomonas aeruginosa DNA vaccine pGACAG-OprF/OprI" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000393 .

obo:VO_0020523 a rdfs:Class ;
  rdfs:label "0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML Nasal Spray Box of 5" ;
  rdfs:subClassOf obo:VO_0020519 , obo:VO_0020953 .

obo:VO_0015036 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 11 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 16 Vaccine 0.12 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 31 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 33 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 45 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 52 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 58 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 6 Vaccine 0.06 MG/ML Prefilled Syringe [Gardasil 9]" ;
  rdfs:subClassOf obo:VO_0015039 .

obo:VO_0003759 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003757 .

obo:VO_0017046 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 100" ;
  rdfs:subClassOf obo:VO_0017031 , obo:VO_0017515 .

obo:VO_0000160 a rdfs:Class ;
  rdfs:label "influenza A (H1N1) 2009 Monovalent Vaccine (Sanofi Pasteur)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003211 , obo:VO_0010415 .

obo:VO_0019575 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003649 , obo:VO_0019544 .

obo:VO_0006058 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent preservative free 3 mcg/0.2 mL dose tris-sucrose formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0015074 a rdfs:Class ;
  rdfs:label "injection form" ;
  rdfs:subClassOf obo:VO_0015062 .

obo:VO_0001359 a rdfs:Class ;
  rdfs:label "carbohydrate vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is primarily composed of carbohydrates." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017180 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetasorbat] Box of 10" ;
  rdfs:subClassOf obo:VO_0017179 , obo:VO_0017183 , obo:VO_0017625 .

obo:VO_0017347 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Quatro Virelon No]" ;
  rdfs:subClassOf obo:VO_0017344 .

obo:VO_0010835 a rdfs:Class ;
  rdfs:label "Leishmania major protein" ;
  rdfs:subClassOf obo:VO_0015478 .

obo:VO_0016854 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] Box of 5 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016802 .

obo:VO_0002604 a rdfs:Class ;
  rdfs:label "wbtA from Francisella tularensis" ;
  rdfs:comment "A wbtA mutant in Francisella tularensis was attenuated and provided protection in mice against challenge with an otherwise lethal dose of either F. tularensis LVS or a fully virulent clinical isolate of F. tularensis type B" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0020722 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020721 .

obo:VO_0002588 a rdfs:Class ;
  rdfs:label "ler from Escherichia coli" ;
  rdfs:comment "A ler deletion mutant derived from wild-type EHEC O157:H7 86-24 was constructed by use of suicide vector pCVD442. Following challenge of 7-day-old suckling mice with O157:H7 EDL933, 75.2% born to group B mothers (immunized with F25) sur- vived, as did 83.0% born to group C mothers (immunized with F105). The surviving suckling mice consistently gained body weight. Only 16.8% of sucking mice born to control group mice survived the challenge" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000161 .

obo:VO_0011131 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Indonesia/CDC594/2006(H5N1))" ;
  rdfs:comment "Viral challenge studies showed that live BacHA derived from Influenza A virus (A/Indonesia/CDC594/2006(H5N1)) was able to provide 100% protection against 5 50% mouse lethal doses (MLD(50)) of homologous (clade 2.1) and heterologous (clade 1) H5N1 [PubMed: 20071572]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0020880 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Viroflu]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020901 .

obo:VO_0018322 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe [Rabipur] Box of 1" ;
  rdfs:subClassOf obo:VO_0018292 , obo:VO_0018305 , obo:VO_0018325 .

obo:VO_0010947 a rdfs:Class ;
  rdfs:label "GNA2001" ;
  rdfs:comment "Protective antigen [PubMed: 10710308]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0019150 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0003773 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 , obo:VO_0010431 .

obo:VO_0002527 a rdfs:Class ;
  rdfs:label "obsolete actA from Listeria monocytogenes" ;
  rdfs:comment "An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes" .

obo:VO_0010954 a rdfs:Class ;
  rdfs:label "PPE18" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0004988 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0001478 a rdfs:Class ;
  rdfs:label "turkey vaccine" ;
  rdfs:comment "Vaccine that used for immunizing turkey." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001461 .

obo:VO_0015105 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015275 .

obo:VO_0002401 a rdfs:Class ;
  rdfs:label "horse EEV, VEV, WEV encephalomyelitis and West Nile Virus vaccine" ;
  rdfs:subClassOf obo:VO_0000752 , obo:VO_0001472 , obo:VO_0001498 , obo:VO_0001499 , obo:VO_0012188 .

obo:OPL_0000161 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum zygote" ;
  rdfs:comment "A Plasmodium falciparum zygote is formed after fertilisation of the macrogamete by a microgamete in the midgut of the mosquito vector. This round form is the only diploid stage in the Plasmodium falciparum life cycle." ;
  rdfs:subClassOf obo:NCBITaxon_5833 , obo:OPL_0000285 .

obo:VO_0004213 a rdfs:Class ;
  rdfs:label "obsolete BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS 0.1 MG/ML" .

obo:VO_0020508 a rdfs:Class ;
  rdfs:label "Yersinia pestis as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0007412 a rdfs:Class ;
  rdfs:label "Mimotope-P10s-PADRE peptide vaccine" ;
  rdfs:comment "Gene name: P10" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0002640 a rdfs:Class ;
  rdfs:label "obsolete guaB from Salmonella spp." ;
  rdfs:comment "A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica" .

obo:VO_0015858 a rdfs:Class ;
  rdfs:label "1 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 25 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015611 .

obo:VO_0007716 a rdfs:Class ;
  rdfs:label "oral therapeutic vaccine V3-X" ;
  rdfs:comment "A cancer vaccine consisting of the tumor-associated antigen (TAA) oligosaccharide antigen sialyl Lewis A (CA19-9; sialylated Lewis A antigen; carbohydrate antigen 19-9; cancer antigen 19-9), with potential immunostimulating and antineoplastic activities. Oral therapeutic vaccine V3-X induces a cytotoxic T-lymphocyte (CTL)-mediated immune response against tumor cells expressing CA19-9. Cholangiocarcinoma (CCA) is a malignant neoplasm originating from the epithelial cells lining the intra- or extrahepatic biliary ducts. This immunotherapeutic formulation is made from pooled heat- and chemically-inactivated blood from donors with CCA for a pill for cholangiocarcinoma patients." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0003242 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injection [Recombivax]" ;
  rdfs:subClassOf obo:VO_0010737 .

obo:VO_0006008 a rdfs:Class ;
  rdfs:label "Hep A live attenuated-IM" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010438 .

obo:VO_0004923 a rdfs:Class ;
  rdfs:label "adolescence age" ;
  rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ;
  rdfs:subClassOf obo:VO_0004921 .

obo:VO_0004645 a rdfs:Class ;
  rdfs:label "CAdVa-Filoviruses (EbMarburg viruses) vaccine" ;
  rdfs:subClassOf obo:VO_0012163 .

obo:VO_0017959 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0017931 .

obo:NCBITaxon_186938 a rdfs:Class ;
  rdfs:label "Respirovirus" ;
  rdfs:subClassOf obo:NCBITaxon_11158 .

obo:VO_0005127 a rdfs:Class ;
  rdfs:label "Viral-like-particle S-MHV SARS vaccine" ;
  rdfs:comment "A SARS VLP vaccine made from the SARS-CoV spike protein (S) and the Nucleocapsid (N), envelope (E) and membrane (M) proteins from mouse hepatitis coronavirus (MHV)" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0012183 .

obo:VO_0007559 a rdfs:Class ;
  rdfs:label "light-emitting Oncolytic Vaccinia virus GL-ONC1 vaccine" ;
  rdfs:comment "An attenuated oncolytic vaccinia virus encoding the light-emitting fusion protein Renilla luciferase-Aequorea green fluorescent protein (RUC-GFP) with potential bioluminescent and antineoplastic activities. Upon administration, light-emitting oncolytic vaccinia virus GL-ONC1 specifically enters tumor cells due to the permeable nature of the tumor vasculature. Once inside the cell, the virus replicates, resulting in tumor cell lysis and the release of mature viral particles into the tumor microenvironment. Released viral particles may then infect and destroy neighboring tumor cells. In addition, the release of tumor-associated antigens (TAAs) by lysed tumor cells into the bloodstream may activate the immune system to mount a cytotoxic T lymphocyte (CTL) response against the tumor. The expression of RUC-GFP by this agent allows for both detection and monitoring of virally infected tumor cells in vivo and vitro with luciferase-mediated bioluminescence imaging and fluorescence imaging techniques." ;
  rdfs:subClassOf obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0004354 a rdfs:Class ;
  rdfs:label "Hepatitis B DNA vaccine pRc/CMV-HBs(S) encoding HBsAg" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000644 .

obo:DOID_3347 a rdfs:Class ;
  rdfs:label "osteosarcoma"@en ;
  rdfs:comment "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus)."@en ;
  rdfs:subClassOf obo:DOID_184 .

obo:VO_0007685 a rdfs:Class ;
  rdfs:label "KRAS-targeted mRNA vaccine" ;
  rdfs:comment "A cancer vaccine used alone or in combination with PD-1 inhibitor in patients with advanced solid tumors with KRAS mutation (G12C, G12D, or G12V) and HLA type HLA-A11:01 or HLA C08:02. The vaccine is a lipid nanoparticle (LNP)-formulated mRNA-based cancer vaccine that targets the most commonly occurring KRAS mutations (G12D, G12V, and G12C). The mRNA-derived KRAS-targeted vaccine V941 (mRNA-5671) is taken up and translated by antigen presenting cells (APCs). Following translation, the epitopes are presented via major histocompatibility complex (MHC) molecules on the surface of the APCs. This leads to an induction of both cytotoxic T-lymphocyte (CTL)- and memory T-cell-dependent immune responses that specifically target and destroy tumor cells harboring these specific KRAS mutations." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0007657 .

obo:VO_0016132 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015882 .

obo:VO_0001889 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002338 .

obo:VO_0003886 a rdfs:Class ;
  rdfs:label "Flublok 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000978 .

obo:VO_0019222 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0020306 .

obo:VO_0001115 a rdfs:Class ;
  rdfs:label "capripoxvirus vaccine vector" ;
  rdfs:comment "a poxvirus vaccine vector that uses an attenuated capripoxvirus strain as the vaccine vector" ;
  rdfs:subClassOf obo:VO_0000447 .

obo:VO_0020276 a rdfs:Class ;
  rdfs:label "obsolete typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe" .

obo:VO_0020512 a rdfs:Class ;
  rdfs:label "poliovirus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0007329 a rdfs:Class ;
  rdfs:label "Belagenpumatucel-L Vaccine" ;
  rdfs:comment "A transforming growth factor beta2 (TGF-beta2) antisense gene-modified allogeneic tumor cell vaccine with potential immunostimulatory and antineoplastic activities. Belagenpumatucel-L is prepared by transfecting allogeneic non-small cell lung cancer (NSCLC) cells with a plasmid containing a TGF-beta2 antisense transgene, expanding the cells, and then irradiating and freezing them. Upon administration, this agent may elicit a cytotoxic T lymphocyte (CTL) response against host NSCLC cells, resulting in decreased tumor cell proliferation; vaccine immunogenicity may be potentiated by suppression of tumor TGF-beta2 production by antisense RNA expressed by the vaccine plasmid TGF-beta2 antisense transgene. Elevated levels of TGF-beta2 are frequently linked to immunosuppression in cancer patients and may be inversely correlated with prognosis in patients with NSCLC." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0017961 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0017932 .

obo:VO_0002615 a rdfs:Class ;
  rdfs:label "obsolete aroC from Salmonella spp." ;
  rdfs:comment "Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" .

obo:VO_0019903 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Flucelvax 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020329 .

obo:VO_0016169 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 20 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0016004 .

obo:VO_0006003 a rdfs:Class ;
  rdfs:label "cholera BivWC" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010455 .

obo:VO_0018304 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabivac] Box of 5" ;
  rdfs:subClassOf obo:VO_0018277 , obo:VO_0018311 .

obo:VO_0010857 a rdfs:Class ;
  rdfs:label "Lef from B. anthracis str. A2012" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010757 .

obo:VO_0020105 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injectable Suspension [Je-Vax]" ;
  rdfs:subClassOf obo:VO_0000066 , obo:VO_0018800 .

obo:OPL_0000415 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Plasmodium yoelii." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0001337 a rdfs:Class ;
  rdfs:label "B7-2 vaccine adjuvant" ;
  rdfs:comment "A cytokine vaccine adjuvant that includes B7-2." ;
  rdfs:subClassOf obo:VO_0001353 .

obo:VO_0020010 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003500 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0004054 a rdfs:Class ;
  rdfs:label "Streptococcus pyogenes FbaA protein vaccine" ;
  rdfs:subClassOf obo:VO_0002852 .

obo:VO_0002487 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0002403 .

obo:VO_0011287 a rdfs:Class ;
  rdfs:label "Tox" ;
  rdfs:comment "In 1923, it was discovered that treatment with formalin eliminated the toxicity of diphtheria toxin (DT) without destroying its immunogenicity. Formalinreated DT, now called diphtheria toxoid, rapidly became the preferred vaccine against diphtheria, and diphtheria toxoid (usually in combined vaccines, such as diphtheriaetanus toxoidsertussis vaccine [DTP] or diphtheriaetanus toxoidscellular pertussis vaccine [DTaP] for children and tetanusiphtheria toxoids vaccine for adults [Td]) is still used throughout the world for active immunization against diphtheria [PubMed: 10657208]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010798 .

obo:VO_0011181 a rdfs:Class ;
  rdfs:label "LpdA" ;
  rdfs:comment "Sera of the challenge group immunized with CCPS-P64kR showed a three-fold higher bactericidal response than the sera of the group immunized with the plain CCPS and they were able to protect against challenge with Neisseria meningococci in the infant rat protection model [PubMed: 15039094]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0003423 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0010042 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum Hsp90" ;
  rdfs:comment "A Hsp90 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:OPL_0000291 a rdfs:Class ;
  rdfs:label "Plasmodium microgametocyte stage" ;
  rdfs:comment "A microgametocyte stage in the Plasmodium lifecycle that occurs either in the bloodstream of a vertebrate host or the midgut of a mosquito vector." ;
  rdfs:subClassOf obo:OPL_0000143 , obo:OPL_0000289 .

obo:VO_0015267 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015261 .

obo:VO_0003112 a rdfs:Class ;
  rdfs:label "Rudivax vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010450 , obo:VO_0010637 .

obo:VO_0001081 a rdfs:Class ;
  rdfs:label "adenovirus serotype 5 vaccine vector" ;
  rdfs:comment "an adenovirus vaccine vector that uses an Adenovirus serotype 5 strain." ;
  rdfs:subClassOf obo:VO_0000136 .

obo:VO_0017633 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017632 , obo:VO_0017636 .

obo:VO_0017931 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0017899 .

obo:VO_0019687 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003757 .

obo:OBI_0000422 a rdfs:Class ;
  rdfs:label "syringe" ;
  rdfs:comment "A processed material which is used to introduce or draw fluids from a material entity. A syringe is made of a piston and body. the movement of the piston in the body determines the amount/volume of fluid to inject or draw"@en ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:VO_0017622 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanus-Impfstoff Merieux] Box of 20" ;
  rdfs:subClassOf obo:VO_0017620 , obo:VO_0017628 .

obo:VO_0004158 a rdfs:Class ;
  rdfs:label "Yersinia pestis DNA vaccine encoding dfF1 protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000648 .

obo:VO_0017311 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / pertactin adsorbed 0.005 MG/ML / Pertussis Vaccine 0.016 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 , obo:VO_0018785 .

obo:VO_0010786 a rdfs:Class ;
  rdfs:label "Human papillomavirus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0002358 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine" ;
  rdfs:subClassOf obo:VO_0002338 , obo:VO_0002372 .

obo:VO_0017789 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.025 MG" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010435 .

obo:VO_0016792 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Infanrix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016730 .

obo:VO_0002313 a rdfs:Class ;
  rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49G6.23)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002465 , obo:VO_0007748 .

obo:VO_0020270 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 UNT/ML Injectable Solution [TE Anatoxal Berna]" ;
  rdfs:subClassOf obo:VO_0020268 , obo:VO_0020269 .

obo:VO_0020389 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020383 .

obo:VO_0003552 a rdfs:Class ;
  rdfs:label "Enterobacteriaceae vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003551 .

obo:VO_0004912 a rdfs:Class ;
  rdfs:label "PfSPZ-GA1 vaccine" ;
  rdfs:comment "Sanaria(R) PfSPZ-GA1 consists of purified, aseptic, cryopreserved Pf sporozoites (NF54 strain) genetically attenuated by removal of the b9 and slarp genes to halt development in the early liver stages." ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0004245 a rdfs:Class ;
  rdfs:label "Recombinant Colorectal cancer antigen GA733 Vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005426 , obo:VO_0007657 .

obo:VO_0020021 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injectable Suspension [Afluria 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020019 , obo:VO_0020299 .

obo:VO_0019300 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020482 .

obo:VO_0002643 a rdfs:Class ;
  rdfs:label "htrA from Salmonella Typhimurium" ;
  rdfs:comment "A htrA mutant in Salmonella typhimurium is attenuated and provides protection in mice against an oral challenge with virulent S. typhimurium SL1344" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0019439 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.2 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0019438 .

obo:VO_0011018 a rdfs:Class ;
  rdfs:label "P145" ;
  rdfs:comment "Following passive immunization, antisera partially protected infant rats from bacteremia resulting from intraperitoneal challenge with bacteria. As assessed by immunoblotting, pooled adult human sera contained antibodies reactive with P145. Following passive immunization, these antisera partially protected infant rats from bacteremia resulting from intraperitoneal challenge with bacteria.  Antibody to P145 may contribute to protection against Brazilian purpuric fever [PubMed: 1937817]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:BFO_0000148 a rdfs:Class ;
  rdfs:label "zero-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:VO_0019827 a rdfs:Class ;
  rdfs:label "influenza A virus A/North Carolina/04/2016 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0007678 a rdfs:Class ;
  rdfs:label "IDO peptide vaccine" ;
  rdfs:comment "A cancer vaccine derived from the immunomodulatory enzyme indoleamine 2,3-dioxygenase (IDO) with potential immunomodulating and antineoplastic activities. It may activate the immune system to induce an immune response against IDO-expressing tumor cells, which may restore the proliferation and activation of various immune cells including cytotoxic T-lymphocytes (CTLs), natural killer cells (NKs), and dendritic cells (DCs), and may eradicate IDO-expressing tumor cells through a CTL-mediated response. This vaccine, using a small fragment of IDO, can be used in combination with either Ipilimumab or Vemurafenib to treat malignant melanoma that has metastasized. " ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0017601 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017597 , obo:VO_0017607 .

obo:VO_0016847 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 20 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016795 .

obo:VO_0005358 a rdfs:Class ;
  rdfs:label "AS01B vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant includes 3-O-desacyl-4'-monophosphoryl lipid A (MPL) from Salmonella minnesota and a saponin molecule (QS-21) purified from plant extract Quillaja saponaria Molina, combined in a liposomal formulation consisting of dioleoyl phosphatidylcholine (DOPC) and cholesterol in phosphate-buffered saline solution." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0018134 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Suspension [M-M-RVAXPRO]" ;
  rdfs:subClassOf obo:VO_0018133 .

obo:VO_0002853 a rdfs:Class ;
  rdfs:label "Francisella tularensis sodC mutant vaccine" ;
  rdfs:comment "A sodC mutant in Francisella tularensis subspecies holarctica was attenuated and provided protection and cleared the infection against lethal challenge in nearly 50% of the mice infected with the deletion of sodC mutant." ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0007452 a rdfs:Class ;
  rdfs:label "human papillomavirus tumor antigen vaccine" ;
  rdfs:comment "A vaccinia viral based vaccine, encoding epitopes of E6 and E7 proteins from human papillomavirus (HPV) types 16 and 18, with immunostimulatory and antineoplastic activities. HPV types 16 and 18 account for approximately 70% of cervical cancers. Vaccination with this HPV-TA (tumor antigen) vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for E6 and E7 from either type 16 or 18 HPV, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0003621 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003620 .

obo:VO_0018710 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Solution [Ervevax]" ;
  rdfs:subClassOf obo:VO_0018807 .

obo:NCBITaxon_2099 a rdfs:Class ;
  rdfs:label "Mesomycoplasma hyopneumoniae" ;
  rdfs:subClassOf obo:NCBITaxon_2895623 .

obo:VO_0006075 a rdfs:Class ;
  rdfs:label "SARS-COV-2 COVID-19 Viral Vector Non-replicating Non-US Vaccine Product (Sputnik Light)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005267 .

obo:VO_0019991 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003611 .

obo:VO_0000089 a rdfs:Class ;
  rdfs:label "Poliovax vaccine" ;
  rdfs:comment "Product Name: Poliovirus Vaccine Inactivated (Human Diploid Cell)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010447 .

obo:VO_0019233 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020495 .

obo:VO_0018481 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0018457 .

obo:VO_0003490 a rdfs:Class ;
  rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010305 , obo:VO_0010415 .

obo:VO_0019977 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML [Fluzone 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020480 .

obo:VO_0002538 a rdfs:Class ;
  rdfs:label "panD from Mycobacterium tuberculosis" ;
  rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0016199 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Gerke" ;
  rdfs:subClassOf obo:VO_0015902 .

obo:VO_0001587 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.11)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001220 , obo:VO_0001522 , obo:VO_0007748 .

obo:VO_0011028 a rdfs:Class ;
  rdfs:label "21B4" ;
  rdfs:comment "Crude extracts of Babesia bovis parasites were systematically fractionated and tested in numerous sequential vaccination/challenge experiments in adult cattle. A short fragment of the third antigen (21B4) has been shown to be protective [PubMed: 1441189]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010827 .

obo:VO_0000797 a rdfs:Class ;
  rdfs:label "cattle gene" ;
  rdfs:subClassOf obo:OGG_0000000002 .

obo:VO_0020711 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1920000000 CFU [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020710 .

obo:VO_0017420 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017670 .

obo:VO_0005168 a rdfs:Class ;
  rdfs:label "CVnCoV vaccine" ;
  rdfs:comment "A SARS-CoV-2 mRNA vaccine developed by CureVac AG and CEPI." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:OPL_0000332 a rdfs:Class ;
  rdfs:label "Neospora caninum tachyzoite" ;
  rdfs:comment "A Neospora caninum that is found intracellular in the intermediate hosts in which asexual replication takes place." ;
  rdfs:subClassOf obo:NCBITaxon_29176 .

obo:VO_0004365 a rdfs:Class ;
  rdfs:label "Herpes simplex virus DNA vaccine gD-2 encoding gD" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:NCBITaxon_1764 a rdfs:Class ;
  rdfs:label "Mycobacterium avium" ;
  rdfs:subClassOf obo:NCBITaxon_1763 .

obo:NCBITaxon_9788 a rdfs:Class ;
  rdfs:label "Equidae" ;
  rdfs:subClassOf obo:NCBITaxon_314145 .

obo:VO_0015203 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Haematogmbh" ;
  rdfs:subClassOf obo:VO_0015200 .

obo:VO_0016312 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 10 by Organon" ;
  rdfs:subClassOf obo:VO_0015927 .

obo:VO_0000391 a rdfs:Class ;
  rdfs:label "Leptospira spp. vaccine" ;
  rdfs:comment "Vaccine that protects against Leptospira spp. infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003553 .

obo:VO_0020971 a rdfs:Class ;
  rdfs:label "Influenza Virus Fragmented, Inactivated, Strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain A / Switzerland / 9715293/2013, Nib-88" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0010303 , obo:VO_0010415 .

obo:UBERON_0013765 a rdfs:Class ;
  rdfs:label "digestive system element" ;
  rdfs:comment "Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements." ;
  rdfs:subClassOf obo:UBERON_0000062 .

obo:VO_0007401 a rdfs:Class ;
  rdfs:label "E1M(184V) peptide vaccine" ;
  rdfs:comment "A proprietary lipid emulsion containing five vaccines: diphtheria, pertussis, tetanus (DPT), Bacille Calmette-Guerin (BCG), measles, Serratia marcescens and pneumococcal, with potential immunostimulating activity. Subcutaneous administration of the DPT/BCG/measles/Serratia/pneumococcus vaccine activates the immune system and may both abrogate tumor-induced immune tolerance and induce an antitumor immune response, which may eradicate the tumor. (NCIT_C62801)." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0017681 a rdfs:Class ;
  rdfs:label "BCG, live, Montreal strain" ;
  rdfs:subClassOf obo:VO_0000771 .

obo:VO_0020539 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Afluria]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020852 .

obo:VO_0001787 a rdfs:Class ;
  rdfs:label "Chlamydia Psittaci Modified Live Chlamydia Vaccine (USDA: 1581.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001217 , obo:VO_0001473 , obo:VO_0007748 , obo:VO_0012174 .

obo:VO_0007314 a rdfs:Class ;
  rdfs:label "Autologous Renal Cell Carcinoma Tumor Lysate-Pulsed Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with renal cell carcinoma (RCC) tumor cell lysate containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous renal cell carcinoma tumor lysate-dendritic cell vaccine may stimulate anti-tumoral cytotoxic T-lymphocyte (CTL) and antibody responses against RCC tumor cells expressing RCC TAAs, resulting in RCC tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0016673 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML [Repevax]" ;
  rdfs:subClassOf obo:VO_0003429 .

obo:VO_0004944 a rdfs:Class ;
  rdfs:label "human age within one month at vaccination" ;
  rdfs:comment "A human child age range at vaccination with the range from the birth to one month after birth at when a vaccination is taken. HepB vaccination is sometimes taken within 12  hours after birth." ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0018790 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000195 , obo:VO_0000508 , obo:VO_0001214 .

obo:VO_0001064 a rdfs:Class ;
  rdfs:label "Mycobacterium smegmatis vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector that uses an attenuated Mycobacterium smegmatis strain" ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0010024 a rdfs:Class ;
  rdfs:label "Leishmania  major KMP-11" ;
  rdfs:comment "A KMP-11 protein that is part of Leishmania  major" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0018913 a rdfs:Class ;
  rdfs:label "influenza A virus A/Norway/16606/2021 (H3N2) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:NCBITaxon_262698 a rdfs:Class ;
  rdfs:label "Brucella abortus bv. 1 str. 9-941" ;
  rdfs:subClassOf obo:NCBITaxon_235 .

obo:VO_0015052 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010441 .

obo:VO_0011102 a rdfs:Class ;
  rdfs:label "US4" ;
  rdfs:comment "In two experiments, mice immunised with phage displaying a single epitope of gG2 (US4) were protected against challenge with a lethal dose of whole HSV-2 [PubMed: 10725197]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010834 .

obo:VO_0010161 a rdfs:Class ;
  rdfs:label "diphtheria, tetanus toxoids and acellular pertussis vaccine, and poliovirus vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0000942 .

obo:VO_0002509 a rdfs:Class ;
  rdfs:label "Salmonella enteritidis vaccine" ;
  rdfs:comment "A bacterial vaccine that protects against infections by Salmonella enterica subsp. enterica serovar Enteritidis." ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0000993 a rdfs:Class ;
  rdfs:label "V1R DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label V1R." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019518 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.0025 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019516 .

obo:VO_0000036 a rdfs:Class ;
  rdfs:label "ETEC vaccine ACAM2010" ;
  rdfs:comment "A CFA/I‐expressing vaccine." ;
  rdfs:subClassOf obo:VO_0000619 .

obo:DOID_635 a rdfs:Class ;
  rdfs:label "acquired immunodeficiency syndrome"@en ;
  rdfs:comment "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS."@en ;
  rdfs:subClassOf obo:DOID_526 .

obo:VO_0017314 a rdfs:Class ;
  rdfs:label "Candida albicans extract / diphtheria toxoid vaccine, inactivated / Glycerin / Proteus mirabilis / Purified Protein Derivative of Tuberculin / tetanus toxin Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0010131 a rdfs:Class ;
  rdfs:label "host age variable" ;
  rdfs:comment "A variable representing the age of the host" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0016288 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0016026 .

obo:VO_0000596 a rdfs:Class ;
  rdfs:label "vaccine clinical trial" ;
  rdfs:comment "Planned process by which a vaccine is tested clinically for safety and effectiveness. Clinical trials are conducted in phases. Classically, clinical trials unfold in three phases in order to gather data and information about a vaccine and its performance. This will form the basis of a dossier submitted to regulatory authorities by way of an application for licensure. After a vaccine is licensed and is being used by large numbers of people, a Phase IV study may or may not be taken for vaccine clinical evaluation." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0000743 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine" ;
  rdfs:comment "A vaccine used to prevent infections of diphtheria, tetanus (lockjaw), pertussis (whooping cough), hepatitis B, and poliovirus." ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010439 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0015778 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 2" ;
  rdfs:subClassOf obo:VO_0015595 .

obo:VO_0011029 a rdfs:Class ;
  rdfs:label "PagA from B. anthracis" ;
  rdfs:comment "Study described the construction and evaluation of an adenovirus vaccine expressing domain 4 of Bacillus anthracis protective antigen, Ad.D4. Ad.D4 elicited antibodies to protective antigen 14 days after a single intramuscular injection, which were further increased upon boosting. Furthermore, two doses of Ad.D4 4 weeks apart were sufficient to protect 67% of mice from toxin challenge [PubMed: 16428747]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010757 .

obo:VO_0002584 a rdfs:Class ;
  rdfs:label "esrC from Edwardsiella tarda" ;
  rdfs:comment "An aroC and esrC mutant is attenuated in zebra fish. This mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 71.3%" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001413 .

obo:VO_0015900 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015624 , obo:VO_0016015 .

obo:VO_0001686 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotype 2, Live Virus Vaccine (USDA: 1631.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0020240 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain Injectable Suspension [Dryvax]" ;
  rdfs:subClassOf obo:VO_0020229 , obo:VO_0020239 .

obo:VO_0018865 a rdfs:Class ;
  rdfs:label "influenza A virus A/Indiana/08/2018 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010299 , obo:VO_0010415 .

obo:VO_0002224 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46E5.24)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002389 , obo:VO_0007748 .

obo:VO_0010846 a rdfs:Class ;
  rdfs:label "Rickettsia spp protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0019953 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Afluria 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019952 , obo:VO_0020301 .

obo:VO_0001205 a rdfs:Class ;
  rdfs:label "CFU reduction per spleen" ;
  rdfs:comment "A reduction of colony forming unit that was measured with the unit of colony forming units (CFU) from the sample of mouse spleen." ;
  rdfs:subClassOf obo:VO_0001164 .

obo:VO_0000579 a rdfs:Class ;
  rdfs:label "Haemophilus somnus vaccine" ;
  rdfs:comment "bacterial vaccine that is used to protect against Haemophilus somnus infection" ;
  rdfs:subClassOf obo:VO_0000661 .

obo:VO_0010012 a rdfs:Class ;
  rdfs:label "Giardia  lamblia CWP2" ;
  rdfs:comment "A CWP2 protein that is part of Giardia  lamblia" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015483 .

obo:VO_0016717 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Solution [Dipht Toxoid Asid]" ;
  rdfs:subClassOf obo:VO_0018796 .

obo:VO_0018286 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018269 , obo:VO_0018273 .

obo:VO_0002234 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.29)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002400 , obo:VO_0007748 .

obo:VO_0017948 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML Prefilled Syringe [ActHIB] Box of 1" ;
  rdfs:subClassOf obo:VO_0017901 .

obo:VO_0001474 a rdfs:Class ;
  rdfs:label "pig vaccine" ;
  rdfs:comment "Vaccine that used for immunizing pig." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001218 .

obo:VO_0001960 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D7.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002362 .

obo:UBERON_0006314 a rdfs:Class ;
  rdfs:label "bodily fluid" ;
  rdfs:comment "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:VO_0016709 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Diphtherie-Adsorbat-Impfstoff Behring]" ;
  rdfs:subClassOf obo:VO_0016672 , obo:VO_0016683 , obo:VO_0016719 .

obo:DOID_120 a rdfs:Class ;
  rdfs:label "female reproductive organ cancer"@en ;
  rdfs:comment "A reproductive organ cancer that is manifested in the female genitals. This includes organs such as the ovaries, fallopian tubes, uterus, cervix, vagina and vulva."@en ;
  rdfs:subClassOf obo:DOID_193 , obo:DOID_229 .

obo:VO_0007441 a rdfs:Class ;
  rdfs:label "MVA-FCU1 TG4023 vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the suicide gene FCU1 with potential antineoplastic activity. FCU1 is a bifunctional yeast cytosine deaminase (CD) / uracil phosphoribosyltransferase (UPRT) fusion gene. Upon intratumoral administration, MVA-FCU1TG4023 enters tumor cells where FCU1 is expressed. Subsequently, the noncytotoxic prodrug 5-fluorocytosine (5-FC) is administered systemically and is deaminated by CD in FCU1- transduced tumor cells into 5-fluorouracil (5-FU), which is then directly metabolized to 5-fluoro-uridine monophosphate (5-FUMP) by UPRT; 5-FUMP may then be further transformed to 5-fluoro-deoxyuridine monophosphate (5-FdUMP), an irreversible inhibitor of thymidylate synthase and, so, DNA synthesis through deprivation of deoxythymidine triphosphate (dTTP). 5-FU and its active metabolites may then selectively kill tumor cells, avoiding toxicity in nonmalignant cells. The MVA viral vector, derived from the replication-competent strain Ankara, is a highly attenuated, replication-defective vaccinia strain incapable of virion assembly" ;
  rdfs:subClassOf obo:VO_0005499 , obo:VO_0007657 .

obo:IAO_8000019 a rdfs:Class ;
  rdfs:label "ontology module subsetted by OWL profile"@en ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:NCBITaxon_54315 a rdfs:Class ;
  rdfs:label "Bovine viral diarrhea virus 2" ;
  rdfs:subClassOf obo:NCBITaxon_11095 .

obo:VO_0002526 a rdfs:Class ;
  rdfs:label "actA from Listeria monocytogenes" ;
  rdfs:comment "An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001403 .

obo:VO_0005264 a rdfs:Class ;
  rdfs:label "authorized COVID-19 vaccine" ;
  rdfs:comment "A COVID-19 vaccine that is authorized for emergent use, which is typically authorized based on an Emergency Use Authorization (EUA)." ;
  rdfs:subClassOf obo:VO_0004908 .

obo:VO_0017149 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0017129 , obo:VO_0017608 .

obo:VO_0000225 a rdfs:Class ;
  rdfs:label "hypersensitivity to neomycin" ;
  rdfs:subClassOf obo:VO_0000224 .

obo:VO_0016784 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016725 .

obo:VO_0019251 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0019513 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0010745 , obo:VO_0019512 .

obo:VO_0004731 a rdfs:Class ;
  rdfs:label "ALVAC-WNV-prM/E vaccine" ;
  rdfs:subClassOf obo:VO_0000752 .

obo:VO_0015810 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 250" ;
  rdfs:subClassOf obo:VO_0015494 .

obo:VO_0005234 a rdfs:Class ;
  rdfs:label "NBP2001 vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine by SK Bioscience" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0002353 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine" ;
  rdfs:subClassOf obo:VO_0002338 , obo:VO_0002345 .

obo:VO_0007213 a rdfs:Class ;
  rdfs:label "AFP Gene Hepatocellular Carcinoma Vaccine" ;
  rdfs:comment "A cancer vaccine composed of naked plasmid DNA of the gene for the tumor-associated antigen alpha-fetoprotein (AFP), a macromolecule that acts as a specific immunologic target for hepatocellular carcinoma. This agent exerts an antitumor effect by inducing cytotoxic T-lymphocytes to attack AFP-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0005429 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0017894 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003347 .

obo:VO_0001456 a rdfs:Class ;
  rdfs:label "Erysipelothrix rhusiopathiae vaccine" ;
  rdfs:comment "bacterial vaccine that is used to protect against Erysipelothrix rhusiopathiae infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003554 .

obo:VO_0001972 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1189.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:NCBITaxon_83555 a rdfs:Class ;
  rdfs:label "Chlamydia abortus" ;
  rdfs:subClassOf obo:NCBITaxon_810 .

obo:VO_0002101 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0002036 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.14)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002326 , obo:VO_0007748 .

obo:VO_0019196 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010432 .

obo:VO_0018872 a rdfs:Class ;
  rdfs:label "influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003519 , obo:VO_0010415 .

obo:VO_0020919 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Vaxigrip Junior]" ;
  rdfs:subClassOf obo:VO_0020913 .

obo:VO_0002815 a rdfs:Class ;
  rdfs:label "obsolete B. melitensis mucR mutant vaccine" ;
  rdfs:comment "A mucR mutant has a significantly reduced degree of colonization in mice and protects against wild type B. melitensis 16M" .

obo:VO_0016093 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015992 .

obo:VO_0016339 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:DOID_12365 a rdfs:Class ;
  rdfs:label "malaria"@en ;
  rdfs:comment "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle."@en ;
  rdfs:subClassOf obo:DOID_1398 .

obo:VO_0020690 a rdfs:Class ;
  rdfs:label "Aconitum napellus extract / ferrous cation / Gelsemium Sempervirens Preparation / Gentiana lutea root extract / Influenza A virus / Lactate / Luffa operculata whole extract / VERATRUM ALBUM Preparation Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0017300 a rdfs:Class ;
  rdfs:label "Bordetella pertussis / diphtheria toxoid vaccine, inactivated / pertactin adsorbed / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0017799 .

obo:VO_0001738 a rdfs:Class ;
  rdfs:label "Duck Virus Hepatitis Modified Live Virus Vaccine (USDA: 14B1.10)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0007748 , obo:VO_0007749 .

obo:VO_0002304 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002480 .

obo:VO_0018259 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML [Tollwut-Impfstoff]" ;
  rdfs:subClassOf obo:VO_0003858 .

obo:VO_0016486 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0003274 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0002149 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.12)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0010911 a rdfs:Class ;
  rdfs:label "GP from Sudan ebolavirus" ;
  rdfs:comment "Cynomolgus macaques were immunized with DNA/rAd5 vaccines expressing ZEBOV (GP) and SEBOV glycoprotein (GP) prior to lethal challenge with BEBOV. Vaccinated subjects developed robust, antigen-specific humoral and cellular immune responses against the GP from ZEBOV as well as cellular immunity against BEBOV GP, and immunized macaques were uniformly protected against lethal challenge with BEBOV [PubMed: 20502688]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0018390 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Injectable Solution [Synflorix]" ;
  rdfs:subClassOf obo:VO_0001245 , obo:VO_0018516 .

obo:VO_0004169 a rdfs:Class ;
  rdfs:label "recombinant baculovirus encoding HA from Influenza A virus (A/Puerto Rico/8/1934(H1N1)) vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000642 .

obo:OPL_0000310 a rdfs:Class ;
  rdfs:label "Vertebrate blood" ;
  rdfs:comment "Blood that is part of or originated from a vertebrate." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:VO_0020330 a rdfs:Class ;
  rdfs:label "Flucelvax 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000980 , obo:VO_0010417 .

obo:VO_0007729 a rdfs:Class ;
  rdfs:label "pUMVC3-IGFBP2-HER2-IGF1R plasmid DNA vaccine" ;
  rdfs:comment "A cancer vaccine containing the mammalian expression vector pUMVC3 encoding epitopes derived from three tumor-associated antigens (TAAs): human insulin-like growth factor-binding protein 2 (IGFBP2), human epidermal growth factor receptor 2 (HER2; ERBB2) and insulin-like growth factor 1 receptor (IGF1R), with potential immunostimulating and antineoplastic activities. The vaccine This activates the immune system to mount a combined response from specific T helper type 1 (Th1) cells, memory T-cells and cytotoxic T-lymphocytes (CTL) against IGFBP2-, HER2-, and IGF1R-expressing tumor cells. This vaccine may prevent cancer from coming back in patients with non-metastatic, node positive, human epidermal growth factor receptor (HER)2 negative breast cancer in which all signs and symptoms have disappeared. Vaccines made from deoxyribonucleic acid (DNA) may help the body build an effective immune response to kill tumor cells. It is given in combination with sargramostim." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 , obo:VO_0007660 .

obo:NCBITaxon_9925 a rdfs:Class ;
  rdfs:label "Capra hircus" ;
  rdfs:subClassOf obo:NCBITaxon_9963 .

obo:VO_0001053 a rdfs:Class ;
  rdfs:label "Nobivac Piro vaccine" ;
  rdfs:subClassOf obo:VO_0000649 , obo:VO_0001074 .

obo:VO_0015586 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection [H-B-Vax II]" ;
  rdfs:subClassOf obo:VO_0015498 , obo:VO_0015544 .

obo:VO_0016508 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Veron" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:VO_0004452 a rdfs:Class ;
  rdfs:label "Prostate cancer DNA vaccine pmPSCA encoding PSCA" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0002176 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 1791.1X)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0020985 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, strain A / Victoria / 361/2011 H3N2 - Derived Strain Used Ivr-165 0.009 MG/ML" ;
  rdfs:subClassOf obo:VO_0020982 .

obo:VO_0015730 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015801 .

obo:VO_0002121 a rdfs:Class ;
  rdfs:label "Canine Coronavirus-Parvovirus Modified Live Virus Vaccine (USDA: 14R1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002393 , obo:VO_0007748 .

obo:VO_0020119 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML Injection [Attenuvax]" ;
  rdfs:subClassOf obo:VO_0020115 , obo:VO_0020118 , obo:VO_0020121 .

obo:VO_0000129 a rdfs:Class ;
  rdfs:label "vaccination frequency" ;
  rdfs:comment "Vaccination frequency is a qualitative term that represents how many times vaccination has occurred." ;
  rdfs:subClassOf obo:PATO_0000044 .

obo:VO_0019572 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2016 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020488 .

obo:VO_0019966 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Flucelvax 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019946 .

obo:VO_0001879 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid (USDA: 4109.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002332 .

obo:VO_0000078 a rdfs:Class ;
  rdfs:label "Mycobax vaccine" ;
  rdfs:comment """Mycobax is a BCG vaccine that is made by Sanofi Pasteur, Ltd.
Ref: http://www.biopharma.com/cgi/full6.lasso?Key=412.65916""" ;
  rdfs:subClassOf obo:VO_0000771 .

obo:VO_0002447 a rdfs:Class ;
  rdfs:label "Mareks Disease-Newcastle Disease vaccine" ;
  rdfs:subClassOf obo:VO_0001222 .

obo:VO_0004115 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae dLOS-P6 vaccine" ;
  rdfs:subClassOf obo:VO_0012185 .

obo:VO_0004634 a rdfs:Class ;
  rdfs:label "rHVT-H5 (clade 2.2 H5N1 HPAIV) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0002923 a rdfs:Class ;
  rdfs:label "Shigella flexneri aroD mutant vaccine" ;
  rdfs:comment "An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0010369 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2022-2023 formula vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0015636 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax]" ;
  rdfs:subClassOf obo:VO_0003422 , obo:VO_0015548 .

obo:VO_0010976 a rdfs:Class ;
  rdfs:label "GNA1162" ;
  rdfs:comment "Protective antigen[PubMed: 10710308]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0015192 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension [Havrix]" ;
  rdfs:subClassOf obo:VO_0015191 , obo:VO_0015276 .

obo:VO_0005347 a rdfs:Class ;
  rdfs:label "ARCT-154 vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by Arcturus Therapeutics, Inc., named as ARCT-154." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0002566 a rdfs:Class ;
  rdfs:label "omp25 from B. melitensis" ;
  rdfs:comment "A omp25 mutant is attenuated and provides protection against challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001400 .

obo:VO_0004234 a rdfs:Class ;
  rdfs:label "gp120 recominant vaccine with MDP adjuvant" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0019972 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML [Agriflu 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020308 .

obo:VO_0006043 a rdfs:Class ;
  rdfs:label "pneumococcal conjugate vaccine 10 valent" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0010453 .

obo:VO_0003595 a rdfs:Class ;
  rdfs:label "Fluzone 2018-2019 Injectable Product" ;
  rdfs:comment "RXN STRENGTH: 0.12 MG/ML (expressed as influenza A virus A/Michigan/45/2015 (H1N1) antigen) / 0.12 MG/ML (expressed as influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen) / 0.12 MG/ML (expressed as influenza B virus B/Maryland/15/2016 antigen)" ;
  rdfs:subClassOf obo:VO_0003594 .

obo:VO_0002549 a rdfs:Class ;
  rdfs:label "aroA from Aeromonas hydrophila" ;
  rdfs:comment "An A. hydrophila aroA mutant is highly attenuated in trout, and a single immunization conferred significant protection from challenge with wild type A. hydrophila" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001406 .

obo:VO_0018487 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0018442 .

obo:VO_0020311 a rdfs:Class ;
  rdfs:label "Fluad Quadrivalent 2020-2021 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0012167 a rdfs:Class ;
  rdfs:label "Hantavirus vaccine" ;
  rdfs:comment "Viral vaccine that protects against Hantavirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0000047 a rdfs:Class ;
  rdfs:label "Fluzone" ;
  rdfs:comment "Product Name: Influenza Virus Vaccine, Trivalent, Types A and B" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0017014 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 20" ;
  rdfs:subClassOf obo:VO_0017003 , obo:VO_0017023 , obo:VO_0017494 .

obo:VO_0015546 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Fendrix]" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0002695 a rdfs:Class ;
  rdfs:label "ssrA from Yersinia pestis" ;
  rdfs:comment "An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001426 .

obo:VO_0001216 a rdfs:Class ;
  rdfs:label "obsolete Lymphocytic choriomeningitis mammarenavirus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Lymphocytic choriomeningitis mammarenavirus" .

obo:VO_0012186 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica vaccine" ;
  rdfs:comment "A vaccine that protects against Yersinia enterocolitica." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000601 .

obo:NCBITaxon_11135 a rdfs:Class ;
  rdfs:label "Feline infectious peritonitis virus" ;
  rdfs:subClassOf obo:NCBITaxon_693997 .

obo:VO_0016206 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 50 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015903 .

obo:VO_0001603 a rdfs:Class ;
  rdfs:label "Avian Paramyxovirus Type 1, Killed Virus Vaccine (USDA: 10C5.11)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001527 , obo:VO_0007748 .

obo:VO_0006083 a rdfs:Class ;
  rdfs:label "typhoid vaccine parenteral acetone-killed dried (U.S. military)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001214 , obo:VO_0010451 .

obo:VO_0002785 a rdfs:Class ;
  rdfs:label "chikungunya virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Chikungunya virus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0007162 a rdfs:Class ;
  rdfs:label "Recombinant Fowlpox-TRICOM Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a recombinant fowlpox virus vector encoding TRICOM. TRICOM is comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3) that may enhance antigen presentation and activate cytotoxic T-cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0000567 a rdfs:Class ;
  rdfs:label "DNA vaccine Rv1806-1807" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000077 .

obo:VO_0003317 a rdfs:Class ;
  rdfs:label "Shingrix vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000484 , obo:VO_0000641 , obo:VO_0000669 , obo:VO_0000712 , obo:VO_0010328 .

obo:VO_0015875 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 50" ;
  rdfs:subClassOf obo:VO_0015615 , obo:VO_0015697 , obo:VO_0016000 .

obo:VO_0019797 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Fluvirin 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003687 , obo:VO_0019795 .

obo:VO_0004082 a rdfs:Class ;
  rdfs:label "V-LSG + V-LSN vaccine" ;
  rdfs:subClassOf obo:VO_0012177 .

obo:VO_0000632 a rdfs:Class ;
  rdfs:label "vaccine-induced humoral immune response" ;
  rdfs:comment "Vaccine induced immue response mediated hrough a body fluid" ;
  rdfs:subClassOf obo:VO_0000135 .

obo:VO_0002274 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4875.A1)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000539 , obo:VO_0000640 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0004336 a rdfs:Class ;
  rdfs:label "Ebola virus recombinant VSVΔG-GP encoding GP vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000726 .

obo:VO_0002998 a rdfs:Class ;
  rdfs:label "West Nile virus C protein mutant vaccine" ;
  rdfs:comment "A virus with a C protein mutation is attenuated in mice and induces significant protection from challenge with wild type West Nile virus" ;
  rdfs:subClassOf obo:VO_0000752 .

obo:VO_0003303 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003299 , obo:VO_0010446 .

obo:VO_0002912 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium tolA mutant vaccine" ;
  rdfs:comment "A tolA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0005800 a rdfs:Class ;
  rdfs:label "Neospora caninum killed protozoa vaccine" ;
  rdfs:comment "A Inactivated vaccine that immunizes against Neospora caninum protozoa." ;
  rdfs:subClassOf obo:VO_0000315 , obo:VO_0001065 .

obo:VO_0001776 a rdfs:Class ;
  rdfs:label "equine influenza modified live virus vaccine (USDA: 1501.10)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000460 , obo:VO_0001178 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0002047 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1288.4A)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0019633 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020491 .

obo:VO_0000716 a rdfs:Class ;
  rdfs:label "conjugate vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0004552 a rdfs:Class ;
  rdfs:label "Foot-and-Mouth Disease Virus Cationic Microparticle-coated DNA vaccine" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001213 .

obo:VO_0004854 a rdfs:Class ;
  rdfs:label "smallpox vaccine live vaccinia virus" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000433 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010452 .

obo:VO_0019920 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Injectable Suspension [Fluzone 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019916 , obo:VO_0020480 .

obo:VO_0018243 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 17500 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0010709 a rdfs:Class ;
  rdfs:label "DT Polio Adsorbed vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000714 , obo:VO_0000943 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0001825 a rdfs:Class ;
  rdfs:label "Porcine Circovirus Type 2, Killed Baculovirus Vector Vaccine (USDA: 19K5.R0)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001524 , obo:VO_0007748 .

obo:VO_0017035 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0017033 .

obo:VO_0007504 a rdfs:Class ;
  rdfs:label "MART-1 Vaccinia vaccine" ;
  rdfs:comment "A cancer vaccine consisting of an attenuated recombinant vaccinia virus expressing the melanoma-associated antigen MART-1. Vaccination with this agent may stimulate cytotoxic host immune responses to melanoma cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020776 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 CELLS Injectable Suspension [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020774 , obo:VO_0020775 , obo:VO_0020807 .

obo:VO_0017688 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Covaxis] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017687 .

obo:VO_0000449 a rdfs:Class ;
  rdfs:label "Moraxella Bovis Bacterin Piliguard Pinkeye-1 trivalent vaccine" ;
  rdfs:subClassOf obo:VO_0000438 .

obo:VO_0016352 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0016035 .

obo:VO_0004671 a rdfs:Class ;
  rdfs:label "SL3261-Leishmania major vaccine" ;
  rdfs:subClassOf obo:VO_0001231 .

obo:VO_0005310 a rdfs:Class ;
  rdfs:label "Th2-biased immune profile" ;
  rdfs:comment "An immune profile that is characterized by the presence of T type 2 Th (Th2) cells that produce IL-4, IL-5, IL-10, and IL-13, which are responsible for strong antibody production, eosinophil activation, and inhibition of several macrophage functions, thus providing phagocyte-independent protective responses." ;
  rdfs:subClassOf obo:VO_0005308 .

obo:VO_0011395 a rdfs:Class ;
  rdfs:label "Human papillomavirus E7 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000667 .

obo:VO_0016751 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] Box of 10" ;
  rdfs:subClassOf obo:VO_0016714 , obo:VO_0016774 .

obo:VO_0015947 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites] Box of 1" ;
  rdfs:subClassOf obo:VO_0015639 , obo:VO_0015721 , obo:VO_0016039 .

obo:VO_0000482 a rdfs:Class ;
  rdfs:label "recombinant protein vaccine preparation" ;
  rdfs:comment "A vaccine preparation process that uses recombinant molecular technology to prepare recombinant protein." ;
  rdfs:subClassOf obo:VO_0000717 .

obo:VO_0016937 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection Box of 5" ;
  rdfs:subClassOf obo:VO_0016933 , obo:VO_0017399 .

obo:VO_0019185 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020489 .

obo:VO_0020873 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC] Box of 10" ;
  rdfs:subClassOf obo:VO_0020872 , obo:VO_0020884 .

obo:VO_0016881 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0016833 , obo:VO_0016842 .

obo:VO_0018684 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML Oral Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018681 .

obo:VO_0007615 a rdfs:Class ;
  rdfs:label "Hsp70 chaperone-based gel composition vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0018294 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Prefilled Syringe [VACCIN RABIQUE INACTIVE MERIEUX]" ;
  rdfs:subClassOf obo:VO_0018280 , obo:VO_0018298 .

obo:VO_0018120 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella virus vaccine Injectable Solution [M-M-RVAXPRO]" ;
  rdfs:subClassOf obo:VO_0018118 .

obo:VO_0004994 a rdfs:Class ;
  rdfs:label "SCB-2019 vaccine" ;
  rdfs:comment "A SARS-CoV-2 trimeric S protein subunit vaccine." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0002448 a rdfs:Class ;
  rdfs:label "chicken Mareks disease-tenosynovitis vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001513 , obo:VO_0012162 .

obo:VO_0015627 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [VACCIN GENHEVAC B]" ;
  rdfs:subClassOf obo:VO_0015585 , obo:VO_0015664 .

obo:VO_0020471 a rdfs:Class ;
  rdfs:label "Fluvirin 2011-2012 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000046 , obo:VO_0010419 .

obo:VO_0015597 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0021178 a rdfs:Class ;
  rdfs:label "0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Injection [Spikevax 2023-2024]" ;
  rdfs:subClassOf obo:VO_0021176 .

obo:VO_0019525 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.01 MG/ML Injection [Recombivax]" ;
  rdfs:subClassOf obo:VO_0015490 .

obo:VO_0007337 a rdfs:Class ;
  rdfs:label "autologous cancer testis antigen specific dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine that uses autologous cancer testis (CT) antigen specific dendritic cell (DC) preceded by decitabine as a demethylating chemotherapy for patients with high-risk neuroblastoma, Ewings sarcoma, osteogenic sarcoma, rhabdomyosarcoma or synovial sarcoma. The mature DC is pulsed with overlapping peptides mixes derived from full-length NY-ESO-1, MAGE-A1, and MAGE-A3." ;
  rdfs:subClassOf obo:VO_0005495 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0016456 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015975 .

obo:VO_0018145 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 10" ;
  rdfs:subClassOf obo:VO_0018144 , obo:VO_0018155 .

obo:VO_0001737 a rdfs:Class ;
  rdfs:label "Duck Virus Enteritis Modified Live Virus Vaccine (USDA: 1461.10)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001525 , obo:VO_0007748 , obo:VO_0007749 .

obo:VO_0001148 a rdfs:Class ;
  rdfs:label "no vaccine protection" ;
  rdfs:subClassOf obo:VO_0000247 .

obo:VO_0020657 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution [ImmuCyst]" ;
  rdfs:subClassOf obo:VO_0020703 .

obo:VO_0019127 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0020582 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [INFLUVAC] by Mylan" ;
  rdfs:subClassOf obo:VO_0020579 .

obo:VO_0019293 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluarix 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020317 .

obo:UBERON_0002530 a rdfs:Class ;
  rdfs:label "gland" ;
  rdfs:comment "An organ that functions as a secretory or excretory organ." ;
  rdfs:subClassOf obo:UBERON_0000062 .

obo:PR_000001154 a rdfs:Class ;
  rdfs:label "Toll-like receptor 3" ;
  rdfs:comment "A Toll-like receptor that is a translation product of the human TLR3 gene or a 1:1 ortholog thereof." ;
  rdfs:subClassOf obo:PR_000001096 .

obo:VO_0000294 a rdfs:Class ;
  rdfs:label "pNGVL DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0016304 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015926 .

obo:VO_0005040 a rdfs:Class ;
  rdfs:label "pAK-4 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pAK-4.  This plasmid is 6600 base pairs in length and contains a CMV promoter and kanamycin and ampicillin resistance genes." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0017641 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [T Immun]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0016475 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0000326 a rdfs:Class ;
  rdfs:label "pUC18 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0018859 a rdfs:Class ;
  rdfs:label "influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0005301 a rdfs:Class ;
  rdfs:label "Alhydroxiquim-II vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0007218 a rdfs:Class ;
  rdfs:label "Allogeneic B7.1/HLA-A1 Transfected Tumor Cell Vaccine" ;
  rdfs:comment "An allogeneic whole cell vaccine, derived from irradiated allogenic tumor cells manipulated to express human B7.1 (CD80 antigen) and human leukocyte antigen (HLA) A1, with potential antitumor activity. Vaccination with allogeneic B7.1/HLA-A1 transfected tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor cell proliferation." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0015003 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix]" ;
  rdfs:subClassOf obo:VO_0015006 .

obo:VO_0018561 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0018717 .

obo:VO_0001100 a rdfs:Class ;
  rdfs:label "persons aged 6 months--24 years" ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:VO_0007466 a rdfs:Class ;
  rdfs:label "immunotherapeutic GSK1572932A vaccine" ;
  rdfs:comment "An immunotherapeutic containing a proprietary adjuvant system combined with a melanoma-associated antigen peptide MAGE-A3 epitope with potential immunomodulating and antineoplastic activities. Intramuscular administration with GSK1572932A may stimulate the immune system to exert both humoral and cellular immune responses against MAGE-A3-expressing tumor cells. MAGE-A3, a tumor associated antigen (TAA), is overexpressed in a variety of tumor cell types, including non-small cell lung cancer (NSCLC), melanoma, head and neck cancer, and bladder cancer." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0000254 a rdfs:Class ;
  rdfs:label "pES DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pES.  This plasmid has a CMV promoter and contains a kanamycin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007381 a rdfs:Class ;
  rdfs:label "hVEGF26-104/RFASE peptide vaccine" ;
  rdfs:comment "A therapeutic cancer vaccine containing a truncated, synthetic peptide mimic of the human angiogenic activator vascular endothelial growth factor (VEGF), consisting of 79 amino acids (amino acids 26-104 of VEGF), and emulsified in the immunoadjuvant RFASE, with potential immunostimulatory and antitumor activities. Upon intramuscular vaccination, the hVEGF26-104 moiety of hVEGF26-104/RFASE acts as an antigen and induces an immune response against VEGF, which results in anti-VEGF antibody binding to and neutralization of endogenous VEGF. This prevents the binding of endogenous VEGF to the VEGF receptor (VEGFR) and blocks VEGFR-mediated endothelial cell signaling, resulting in an inhibition of both angiogenesis and tumor cell proliferation. VEGF plays a key role in angiogenesis, tumor cell proliferation and invasion. RFASE, which belongs to the group of sulpholipopolysaccharides (SLPs), is a synthetic polysaccharide covalently coupled to lipid groups and sulphate groups, and is able to induce a strong humoral immune response upon antigen administration." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0000118 a rdfs:Class ;
  rdfs:label "microbial derivative vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that contains microbial derived material." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002207 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4629.27)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002396 , obo:VO_0007748 .

obo:VO_0017869 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.05 MG" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0002138 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002395 , obo:VO_0007748 .

obo:VO_0020441 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 10" ;
  rdfs:subClassOf obo:VO_0020408 , obo:VO_0020417 .

obo:VO_0019467 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 50 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003456 .

obo:VO_0011094 a rdfs:Class ;
  rdfs:label "PreS2 middle surface protein" ;
  rdfs:comment "The immunological protection of pVAX-PS, a DNA vaccine, was assessed in the tree shrews model. pVAX-PS was constructed by inserting the gene encoding the middle (pre-S2 plus S) envelope protein of HBV into a plasmid vector pVAX1.  Results indicated that pVAX-PS immunization could induce remarkable humoral immune response and prevent the experimental tree shrews from infection of HBV [PubMed: 12932306]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010781 .

obo:VO_0002677 a rdfs:Class ;
  rdfs:label "msbB2 from Shigella" ;
  rdfs:comment "A virG, senA, senB, and msbB2 mutant (WRSs3) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs3 is comparable to live attenuated vaccine strain WRSS1" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000169 .

obo:CHEBI_53426 a rdfs:Class ;
  rdfs:label "polysorbate 80" ;
  rdfs:comment "A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by an oleoyl group." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0004065 a rdfs:Class ;
  rdfs:label "Plasmodium berghei MSP1 Protein vaccine" ;
  rdfs:subClassOf obo:VO_0002513 .

obo:VO_0003770 a rdfs:Class ;
  rdfs:label "FluLaval Quadrivalent 2017-2018 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003768 .

obo:VO_0018594 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0018768 .

obo:OPL_0000408 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi sporozoite stage" ;
  rdfs:comment "A sporozoite stage in the Plasmodium knowlesi." ;
  rdfs:subClassOf obo:OPL_0000152 , obo:OPL_0000300 , obo:OPL_0000417 .

obo:VO_0007705 a rdfs:Class ;
  rdfs:label "MVA-BN-CV301 vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a proprietary version of the recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding both the two human tumor-associated antigens (TAAs) carcinoembryonic antigen (CEA) and mucin-1 (MUC-1), and TRICOM, which is comprised of the three human immune-enhancing co-stimulatory molecules B7-1, ICAM-1 and LFA-3, with potential immunostimulatory and antineoplastic activities. MVA-BN-CV301, followed by multiple boosting doses of the fowlpox virus (FPV) vaccine CV301 may lead to a cytotoxic T-lymphocyte (CTL) response against CEA- and MUC-1-expressing tumor cells is activated. In addition, the CV301-dependent anti-tumor CTL response upregulates the expression of programmed cell death ligand 1 (PD-L1); therefore, when CV301 is combined with a programmed cell death 1 (PD-1) immune checkpoint inhibitor, the antitumor effect may be increased. CV301 is a poxviral-based vaccine comprised of recombinant Modified vaccinia Ankara (MVA-BN-CV301, prime) and recombinant fowlpox (FPV-CV301, boost). CV301 contains transgenes encoding two (2) tumor-associated antigens (TAA), mucin 1 (MUC1) and carcinoembryonic antigen (CEA), as well as three costimulatory molecules (B7.1, intercellular adhesion molecule 1 (ICAM-1) and lymphocyte function-associated antigen 3 (LFA-3), designated TRICOM). It is given in combination with SX-682 and M7824 for patients with Triple Negative Breast Cancer (TNBC) and Human papilloma virus (HPV) negative head and neck squamous cell carcinoma (HNSCC)." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0004563 a rdfs:Class ;
  rdfs:label "Leptospira interrogans DNA vaccine pTARGET/ LigBrep" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000391 .

obo:VO_0003885 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML [Flublok 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003882 , obo:VO_0004914 .

obo:VO_0005067 a rdfs:Class ;
  rdfs:label "pVacc4 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pVacc4.  This plasmid is a derivative of pVacc1 and contains a CMV promoter." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015181 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015180 , obo:VO_0015188 , obo:VO_0015269 .

obo:VO_0004724 a rdfs:Class ;
  rdfs:label "RSV-H7 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0001314 a rdfs:Class ;
  rdfs:label "Specol vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant that is a water-in-oil emulsion that is used as an adjuvant and has immunostimulating properties similar to Freund's complete adjuvant (FCA)." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:NCBITaxon_107819 a rdfs:Class ;
  rdfs:label "Clostridium perfringens D" ;
  rdfs:subClassOf obo:NCBITaxon_1502 .

obo:VO_0002716 a rdfs:Class ;
  rdfs:label "UL0 from Gallid herpesvirus 1" ;
  rdfs:comment "A UL0 mutant in infectious laryngotracheitis virus (ILTV) was attenuated. Chickens immunized with UL0-negative ILTV were protected from clinical disease after subsequent infection with virulent ILTV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001435 .

obo:VO_0021010 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 19400 PFU Injection [Zostavax]" ;
  rdfs:subClassOf obo:VO_0021008 , obo:VO_0021009 .

obo:VO_0020812 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe [Kinrix]" ;
  rdfs:subClassOf obo:VO_0000067 .

obo:VO_0011512 a rdfs:Class ;
  rdfs:label "Dobrava-Belgrade virus S nucleocapsid protein vaccine" ;
  rdfs:subClassOf obo:VO_0012167 .

obo:VO_0003331 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 8 vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003246 .

obo:VO_0002513 a rdfs:Class ;
  rdfs:label "Plasmodium berghei vaccine" ;
  rdfs:comment "a malaria vaccine that protects against malaria caused by Plasmodium berghei." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000761 .

obo:FMA_12278 a rdfs:Class ;
  rdfs:label "Hormone" ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0015864 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015613 , obo:VO_0015683 , obo:VO_0015992 .

obo:VO_0004796 a rdfs:Class ;
  rdfs:label "MVA-PvTRAP vaccine" ;
  rdfs:subClassOf obo:VO_0000758 .

obo:VO_0020382 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 10000000000 UNT Oral Powder" ;
  rdfs:subClassOf obo:VO_0020369 .

obo:VO_0018279 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Injectable Suspension [Tollwut-Impfstoff]" ;
  rdfs:subClassOf obo:VO_0018259 , obo:VO_0018266 , obo:VO_0018288 .

obo:VO_0001987 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002361 .

obo:VO_0019757 a rdfs:Class ;
  rdfs:label "influenza A virus A/Delaware/39/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Nebraska/14/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0004008 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae SrtA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0016000 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0015660 , obo:VO_0015786 .

obo:VO_0019482 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine Injection [COMVAX]" ;
  rdfs:subClassOf obo:VO_0000028 , obo:VO_0019481 .

obo:VO_0001586 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.10)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001220 , obo:VO_0001522 , obo:VO_0007748 .

obo:CL_0000226 a rdfs:Class ;
  rdfs:label "single nucleate cell" ;
  rdfs:comment "A cell with a single nucleus." ;
  rdfs:subClassOf obo:CL_0000255 , obo:CL_0002242 .

obo:VO_0018644 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine / L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine / L1 protein, Human papillomavirus type 6 Vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018798 .

obo:VO_0000832 a rdfs:Class ;
  rdfs:label "modified Yersinia pestis with TLR4-stimulating LPS vaccine" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0019786 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003745 .

obo:VO_0017536 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017533 .

obo:VO_0018520 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:NCBITaxon_662 a rdfs:Class ;
  rdfs:label "Vibrio" ;
  rdfs:subClassOf obo:NCBITaxon_641 .

obo:VO_0015557 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015528 , obo:VO_0015559 .

obo:VO_0005504 a rdfs:Class ;
  rdfs:label "vaccine against infectious disease" ;
  rdfs:comment "Vaccine against an infectious disease caused by specific pathogen(s)." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005503 .

obo:UBERON_0001046 a rdfs:Class ;
  rdfs:label "hindgut" ;
  rdfs:comment "The caudalmost subdivision of a digestive tract." ;
  rdfs:subClassOf obo:UBERON_0004921 .

obo:VO_0005138 a rdfs:Class ;
  rdfs:label "CRT-N SARS vaccine" ;
  rdfs:comment "A SARS DNA vaccine made from  encoding calrectulin linked to a SARS-CoV N protein" ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0020960 a rdfs:Class ;
  rdfs:label "Influenza B virus vaccine, B-Brisbane-60-2008-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain / Influenza Virus Vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0017630 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0017610 .

obo:VO_0017191 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol] Box of 1 by Novartis" ;
  rdfs:subClassOf obo:VO_0017190 .

obo:VO_0001817 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0001176 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0016703 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 50 LFU/ML" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0020646 a rdfs:Class ;
  rdfs:label "1 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0021013 .

obo:VO_0001575 a rdfs:Class ;
  rdfs:label "Brucella Abortus Strain 19, Live Culture Vaccine (USDA: 1251.01)" ;
  rdfs:subClassOf obo:VO_0000022 , obo:VO_0000813 , obo:VO_0001214 .

obo:VO_0011170 a rdfs:Class ;
  rdfs:label "M matrix protein" ;
  rdfs:comment "Lewis rats were immunized with recombinant vaccinia virus (VV) expressing various proteins of measles virus (MV). VVM (Matrix Protein) -immunized rats were partially protected from MV challenge [PubMed: 1833505]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010784 .

obo:VO_0004347 a rdfs:Class ;
  rdfs:label "HIV recombinant vector vaccine MVA-gag encoding gag" ;
  rdfs:subClassOf obo:VO_0000295 , obo:VO_0000484 .

obo:VO_0021136 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Washington/19/2020 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0019456 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Tenivac]" ;
  rdfs:subClassOf obo:VO_0000102 , obo:VO_0019454 .

obo:VO_0018633 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 12 BAU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018631 , obo:VO_0018800 .

obo:VO_0003916 a rdfs:Class ;
  rdfs:label "FLUAD 2015-2016 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003910 .

obo:OPL_0000117 a rdfs:Class ;
  rdfs:label "Homo sapiens blood" ;
  rdfs:comment "Blood that is part of or originated from a human (Homo sapiens)." ;
  rdfs:subClassOf obo:OPL_0000320 , obo:UBERON_0000178 .

obo:VO_0011477 a rdfs:Class ;
  rdfs:label "Helicobacter pylori DNA vaccine encoding UreB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012181 .

obo:VO_0004539 a rdfs:Class ;
  rdfs:label "Erysipelothrix rhusiopathiae DNA vaccine pcD-ACSC" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001456 .

obo:VO_0016619 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Adult] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016599 .

obo:VO_0018407 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 23F vaccine 0.001 MG" ;
  rdfs:subClassOf obo:VO_0003252 .

obo:VO_0018554 a rdfs:Class ;
  rdfs:label "0.5 ML Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution by Aventis" ;
  rdfs:subClassOf obo:VO_0018553 .

obo:VO_0019816 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0020908 a rdfs:Class ;
  rdfs:label "Influenza A virus Injectable Suspension [Alpha RIX Tetra]" ;
  rdfs:subClassOf obo:VO_0020907 .

obo:VO_0010232 a rdfs:Class ;
  rdfs:label "tuberculin skin test; purified protein derivative, multipuncture device" ;
  rdfs:subClassOf obo:NCIT_C85994 .

obo:VO_0003931 a rdfs:Class ;
  rdfs:label "Fluad 2018-2019 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003930 .

obo:OPL_0000152 a rdfs:Class ;
  rdfs:label "sporozoite stage" ;
  rdfs:comment "A parasite lifecycle stage of some sporozoans where cells divide through sporogony producing daughter cells called sporozoites that infect new hosts." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0000727 a rdfs:Class ;
  rdfs:label "Herpesvirus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Herpesvirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0000643 a rdfs:Class ;
  rdfs:label "licensed cattle vaccine" ;
  rdfs:comment "a vaccine with license that is used for cattle." ;
  rdfs:subClassOf obo:VO_0000363 , obo:VO_0001466 .

obo:VO_0017120 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 20 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0017118 .

obo:VO_0019392 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Daptacel]" ;
  rdfs:subClassOf obo:VO_0000029 , obo:VO_0018770 .

obo:NCBITaxon_12092 a rdfs:Class ;
  rdfs:label "Hepatovirus A" ;
  rdfs:subClassOf obo:NCBITaxon_12091 .

obo:VO_0000438 a rdfs:Class ;
  rdfs:label "Moraxella bovis bacterin vaccine" ;
  rdfs:comment "a Moraxella bovis vaccine that is prepared using a bacterial bacterin." ;
  rdfs:subClassOf obo:VO_0000437 .

obo:VO_0010965 a rdfs:Class ;
  rdfs:label "FyuA" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0002391 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0001471 , obo:VO_0004897 .

obo:VO_0016396 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0020452 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0020415 , obo:VO_0020428 .

obo:VO_0002133 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.2A)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002421 , obo:VO_0007748 .

obo:VO_0019622 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020334 .

obo:VO_0003434 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0018673 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 [Rotarix]" ;
  rdfs:subClassOf obo:VO_0010738 , obo:VO_0018672 .

obo:VO_0002223 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46E5.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002390 , obo:VO_0007748 .

obo:VO_0003815 a rdfs:Class ;
  rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML [Flumist Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003808 .

obo:VO_0002369 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Mannheimia Haemolytica Toxoid" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0001523 , obo:VO_0002358 .

obo:VO_0000509 a rdfs:Class ;
  rdfs:label "Nontypeable Haemophilus influenzae P5 peptide MVF/H3 vaccine" ;
  rdfs:subClassOf obo:VO_0000471 .

obo:VO_0000137 a rdfs:Class ;
  rdfs:label "combination vaccine role" ;
  rdfs:comment "A vaccine role that indicates the vaccine being a combination vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0018066 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 10" ;
  rdfs:subClassOf obo:VO_0018065 , obo:VO_0018075 , obo:VO_0018151 .

obo:VO_0007134 a rdfs:Class ;
  rdfs:label "P53-Synthetic Long Peptides Vaccine" ;
  rdfs:comment "A peptide vaccine consisting of 10 synthetic long peptides (SLPs), 25-30 amino acids in size and derived from the middle portion of p53 (amino acids 70-251), mixed with the adjuvant Montanide ISA-51 with potential immunostimulatory and antitumor activities. Upon administration, p53 synthetic long peptide (70-251) vaccine may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL) response against p53-expressing tumor cells. p53, a tumor associated antigen (TAA), may be overexpressed in variety of cancer cell types." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0005000 a rdfs:Class ;
  rdfs:label "pCAGGSP7 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCAGGSP7. This plasmid has a polylinker containing KpnI, XhoI, ClaI, EcoRV, SmaI, Not1 and Sac1 sites inserted into the EcoRI site of pCAGGS." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000303 a rdfs:Class ;
  rdfs:label "Brucella suis strain VTRS1 vaccine" ;
  rdfs:subClassOf obo:VO_0001136 .

obo:VO_0004459 a rdfs:Class ;
  rdfs:label "Chinese Schistosoma japonicum DNA vaccine SjCTPI-Hsp70" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001229 .

obo:VO_0001277 a rdfs:Class ;
  rdfs:label "viral vaccine immunization" ;
  rdfs:subClassOf obo:VO_0000494 .

obo:VO_0011523 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine pcDNA3-MIC3" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:VO_0016948 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 4 LFU/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0016947 , obo:VO_0017406 .

obo:VO_0003336 a rdfs:Class ;
  rdfs:label "live attenuated vaccine-induced down-regulated gene expression compared to infection with wild type pathogen" ;
  rdfs:comment "a vaccine-induced down-regulation gene expression that occurs in live attenuated vaccine and compared with the host system infected with live wild type virulent strain which is the parent strain of this live attenuated vaccine. " ;
  rdfs:subClassOf obo:VO_0000239 .

obo:VO_0004819 a rdfs:Class ;
  rdfs:label "Rotarix Oral Liquid Product" ;
  rdfs:subClassOf obo:VO_0010738 .

obo:VO_0003810 a rdfs:Class ;
  rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML [Flumist 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003806 .

obo:VO_0017929 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.3 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017895 .

obo:VO_0003068 a rdfs:Class ;
  rdfs:label "obsolete RB51 induced host immune response" .

obo:VO_0021166 a rdfs:Class ;
  rdfs:label "DTP- Haemophilus influenzae type b conjugate and hepatitis b vaccine (non-US)" ;
  rdfs:comment "A DTP-Haemophilus influenzae type b conjugate and hepatitis B vaccine that is used outside USA." ;
  rdfs:subClassOf obo:VO_0005457 .

obo:VO_0020342 a rdfs:Class ;
  rdfs:label "Flulaval Quad 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003071 , obo:VO_0010417 .

obo:VO_0018074 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018065 .

obo:VO_0010053 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum Pfs25" ;
  rdfs:comment "A Pfs25 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0002937 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica ompR mutant vaccine" ;
  rdfs:comment "A ompR mutant in Yersinia enterocolitica was attenuated and provided a partial protection from challenge in mice" ;
  rdfs:subClassOf obo:VO_0012186 .

obo:VO_0011158 a rdfs:Class ;
  rdfs:label "MspC" ;
  rdfs:comment "Study showed that cationic distearoyl phosphatidylcholine (DSPC) liposomes, when used as vaccine adjuvant with the immunodominant 63-kDa glycoprotein (gp63, mspC) of Leishmania donovani promastigotes, induced significant protection against progressive visceral leishmaniasis in susceptible BALB/c mice. gp63 used without adjuvant elicited partial protection but in association with liposomes exhibited marked resistance in both the livers and spleens of the mice challenged 10 days after the last vaccination [PubMed: 18195029]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0001490 a rdfs:Class ;
  rdfs:label "canine adenovirus Type 2 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Canine Adenovirus Type 2 (Canine adenovirus 2) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000037 .

obo:VO_0016565 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.04 MG/ML [Twinrix]" ;
  rdfs:subClassOf obo:VO_0000113 , obo:VO_0016556 .

obo:VO_0002822 a rdfs:Class ;
  rdfs:label "obsolete B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA" ;
  rdfs:comment "A virB2 mutant is attenuated in Brucella melitensis and provides protection in mice" .

obo:VO_0010863 a rdfs:Class ;
  rdfs:label "VP35 from Reston ebolavirus" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0018514 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 20 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0018506 .

obo:DOID_417 a rdfs:Class ;
  rdfs:label "autoimmune disease"@en ;
  rdfs:comment "An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues."@en ;
  rdfs:subClassOf obo:DOID_2914 .

obo:VO_0000754 a rdfs:Class ;
  rdfs:label "marker vaccine" ;
  rdfs:comment "A vaccine that is used in conjunction with diagnostic tests to differentiate vaccinated animals from carrier animals. It can be a subunit or a gene-deleted vaccine." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0015991 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe Box of 50" ;
  rdfs:subClassOf obo:VO_0015485 , obo:VO_0015775 .

obo:VO_0010206 a rdfs:Class ;
  rdfs:label "meningococcal B vaccine, recombinant, OMV, adjuvanted" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0010444 .

obo:VO_0000502 a rdfs:Class ;
  rdfs:label "Inactivated ETEC expressing CFA/I and CFA/II vaccine" ;
  rdfs:subClassOf obo:VO_0000974 .

obo:VO_0004875 a rdfs:Class ;
  rdfs:label "Adenovirus Type 4 Vaccine Live 32000 UNT Delayed Release Oral Tablet" ;
  rdfs:subClassOf obo:VO_0004874 .

obo:VO_0010092 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii GRA16" ;
  rdfs:comment "A GRA16 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0004088 a rdfs:Class ;
  rdfs:label "YFV17D/LAS-GPC vaccine" ;
  rdfs:subClassOf obo:VO_0012177 .

obo:VO_0000412 a rdfs:Class ;
  rdfs:label "Brucella melitensis P39 recombinant protein vaccine" ;
  rdfs:comment "A Brucella subunit vaccine that uses recombinant Brucella melitensis 16M P39, a putative periplasmic binding protein." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0001223 .

obo:VO_0019746 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020495 .

obo:VO_0020498 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0016728 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0016713 , obo:VO_0016733 .

obo:VO_0003782 a rdfs:Class ;
  rdfs:label "Flucelvax 2015-2016 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003780 .

obo:VO_0000366 a rdfs:Class ;
  rdfs:label "liposome-based vaccine adjuvant" ;
  rdfs:comment "A particulate antigen delivery system vaccine adjuvant that contains particles made up of concentric lipid membranes containing phospholipids and other lipids in a bilayer configuration separated by aqueous compartments. It is a relatively stable but non-covalently-bound complex of saponin adjuvant Quil-A, cholesterol and amphipathic antigen in a molar ratio of approximately 1:1:1. The spectrum of viral capsid antigens and non-viral amphipathic antigens of relevance for human vaccination, incorporated into ISCOMs, comprises influenza, measles, rabies, gp340 from EB-virus, gp120 from HIV, Plasmodium falciparum and Trypanosoma cruzi." ;
  rdfs:subClassOf obo:VO_0001356 .

obo:VO_0001694 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 1 & 3, Live Virus Vaccine (USDA: 16L1.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0020281 a rdfs:Class ;
  rdfs:label "varicella zoster virus glycoprotein E Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010326 .

obo:VO_0016965 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injection [Adt Booster] Box of 5" ;
  rdfs:subClassOf obo:VO_0016964 , obo:VO_0016967 , obo:VO_0017422 .

obo:VO_0020801 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 UNT Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020799 , obo:VO_0020804 .

obo:NCBITaxon_44088 a rdfs:Class ;
  rdfs:label "Canarypox virus" ;
  rdfs:subClassOf obo:NCBITaxon_10260 .

obo:VO_0001955 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B6.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002360 .

obo:VO_0018224 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 5000 UNT / Rubella virus 1000 UNT [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018250 .

obo:VO_0000664 a rdfs:Class ;
  rdfs:label "Poliovirus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Poliovirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003547 .

obo:VO_0020040 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain Nasal Spray [Flumist 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020038 , obo:VO_0020348 .

obo:VO_0017307 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 30 LFU/ML / Pertussis Vaccine 0.0468 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension [Tripacel]" ;
  rdfs:subClassOf obo:VO_0017304 , obo:VO_0017306 .

obo:VO_0016406 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015955 , obo:VO_0015961 .

obo:VO_0015773 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015489 .

obo:VO_0018643 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Prefilled Syringe [Japanese encephalitis GCVC]" ;
  rdfs:subClassOf obo:VO_0018801 .

obo:NCBITaxon_1719 a rdfs:Class ;
  rdfs:label "Corynebacterium pseudotuberculosis" ;
  rdfs:subClassOf obo:NCBITaxon_1716 .

obo:VO_0003654 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2018-2019 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003650 .

obo:VO_0018800 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003948 , obo:VO_0018612 .

obo:VO_0002408 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine" ;
  rdfs:subClassOf obo:VO_0002407 , obo:VO_0012180 .

obo:VO_0002846 a rdfs:Class ;
  rdfs:label "Francisella tularensis guaB mutant vaccine" ;
  rdfs:comment "A guaB mutant is attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0017131 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [T Wellcovax] Box of 1" ;
  rdfs:subClassOf obo:VO_0017130 , obo:VO_0017141 , obo:VO_0017596 .

obo:VO_0017169 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol] Box of 20 by Novartis" ;
  rdfs:subClassOf obo:VO_0017168 .

obo:VO_0010810 a rdfs:Class ;
  rdfs:label "Infectious Hematopoietic Necrosis Virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0000318 a rdfs:Class ;
  rdfs:label "pTARGET DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:OPL_0000280 a rdfs:Class ;
  rdfs:label "Plasmodium salivary gland-derived sporozoite" ;
  rdfs:comment "A Plasmodium sporozoite that is found in the salivary glands of the mosquito vector." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000278 .

obo:VO_0001828 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.23)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0002477 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0020438 a rdfs:Class ;
  rdfs:label "1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 50 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020407 .

obo:VO_0002385 a rdfs:Class ;
  rdfs:label "chicken bursal disease-reovirus vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001497 , obo:VO_0001513 .

obo:VO_0001948 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0020765 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0020760 .

obo:VO_0001614 a rdfs:Class ;
  rdfs:label "Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.22)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0004530 a rdfs:Class ;
  rdfs:label "Leishmania major DNA vaccine pcLACK + IL-22" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001231 .

obo:VO_0011254 a rdfs:Class ;
  rdfs:label "VP2 from Rotavirus" ;
  rdfs:comment "Both inbred BALB/c and outbred CD-1 mice were immunized with rotavirus VP2/6-rVLPs (2/6-VLPs) combined with CT-E29H, orally or intranasally (i.n.), and the comparative efficacy of different formulations was then determined.  Two immunizations with 2-6VLPs and CT-E29H were sufficient to protect BALB/c mice, regardless of the route of administration [PubMed: 11270595]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010789 .

obo:OPL_0000242 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum erythrocytic merozoite" ;
  rdfs:comment "A Plasmodium falciparum merozoite that is produced in an erythrocytic schizont and released into the bloodstream of a human host. These forms invade erythrocytes." ;
  rdfs:subClassOf obo:OPL_0000130 , obo:OPL_0000271 .

obo:VO_0010341 a rdfs:Class ;
  rdfs:label "CYFENDUS vaccine" ;
  rdfs:subClassOf obo:VO_0000014 .

obo:VO_0004865 a rdfs:Class ;
  rdfs:label "MenHibrix Injectable Product" ;
  rdfs:subClassOf obo:VO_0000031 .

obo:VO_0016446 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0002422 a rdfs:Class ;
  rdfs:label "equine EEV and WEV encephalomyelitis-influenza vaccine-tetanus toxoid" ;
  rdfs:subClassOf obo:VO_0000460 , obo:VO_0002420 .

obo:VO_0002727 a rdfs:Class ;
  rdfs:label "M2-2 from Human metapneumovirus" ;
  rdfs:comment "An M2-2 mutant is attenuated in African green monkeys and induced protection from challenge with wild type HMPV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001438 .

obo:VO_0017963 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group B vaccine 0.3 MG/ML Injectable Suspension [Boostrix] by GSK" ;
  rdfs:subClassOf obo:VO_0017937 .

obo:OPL_0000268 a rdfs:Class ;
  rdfs:label "Plasmodium macrogametocyte" ;
  rdfs:comment "A Plasmodium gametocyte that is a female gametocyte of Plasmodium and found either in the bloodstream of the vertebrate host or midgut of mosquito vector. The macrogametocyte is a precursor of the macrogamete." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000267 .

obo:VO_0019430 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Tdvax]" ;
  rdfs:subClassOf obo:VO_0017670 .

obo:VO_0006086 a rdfs:Class ;
  rdfs:label "vaccinia (smallpox) vaccine diluted" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010452 .

obo:VO_0000685 a rdfs:Class ;
  rdfs:label "obsolete recombinant bacterial vector vaccine role" ;
  rdfs:comment "A recombinant vector vaccine role that inheres in a bacterium that carries a vaccine antigen for development of a particular vaccine " .

obo:VO_0015625 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Fendrix]" ;
  rdfs:subClassOf obo:VO_0015580 , obo:VO_0015663 .

obo:UBERON_0010047 a rdfs:Class ;
  rdfs:label "oral gland" ;
  rdfs:comment "Gland of the epithelium lining the oral cavity. The most common are the salivary glands." ;
  rdfs:subClassOf obo:UBERON_0003408 .

obo:VO_0016773 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0016719 .

obo:VO_0000113 a rdfs:Class ;
  rdfs:label "Twinrix vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000712 , obo:VO_0000714 , obo:VO_0000745 , obo:VO_0001214 .

obo:VO_0020110 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.04 MG/ML Injection [Gardasil]" ;
  rdfs:subClassOf obo:VO_0000049 , obo:VO_0020109 .

obo:VO_0011001 a rdfs:Class ;
  rdfs:label "YscF from Y. pestis KIM 10" ;
  rdfs:comment "Modified YscF antigens were able to partially protect immunized mice at various levels against lethal challenge with Y. pestis KIM 1001 strain [PubMed: 18291562]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0004628 a rdfs:Class ;
  rdfs:label "A2-CPA-CPB(-CTE)-recombinant L. tarentolae vaccine" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0012159 .

obo:VO_0003325 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 2 vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003225 .

obo:VO_0010109 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii PGAM2" ;
  rdfs:comment "A PGAM2 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0016593 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Paediatric] Box of 1" ;
  rdfs:subClassOf obo:VO_0016582 , obo:VO_0016597 .

obo:VO_0007178 a rdfs:Class ;
  rdfs:label "VHL16 Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL16 peptide, also known as S111I, is a point mutation variant of the VHL tumor suppressor protein; the mutation is in amino acid position 111. Vaccination with this agent may stimulate a cytotoxic T-cell response in patients with VHL-associated cancers that express this variant of the VHL tumor suppressor protein." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0015029 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML Injection [Varivax]" ;
  rdfs:subClassOf obo:VO_0015031 .

obo:VO_0016435 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Haematogmbh" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:NCBITaxon_6181 a rdfs:Class ;
  rdfs:label "Schistosoma" ;
  rdfs:subClassOf obo:NCBITaxon_33317 .

obo:VO_0019445 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 20 LFU/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018787 .

obo:VO_0019502 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003431 .

obo:VO_0018539 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018797 .

obo:VO_0011062 a rdfs:Class ;
  rdfs:label "Gam82" ;
  rdfs:comment "Animals vaccinated with Gam82 and challenged with E. maxima showed lower oocyst shedding and reduced intestinal pathology compared with non-vaccinated and parasite-challenged animals. Gam82 vaccination also stimulated the production of antigen-specific serum antibodies and induced greater levels of IL-2 and IL-15 mRNAs compared with non-vaccinated controls. These results demonstrate that the Gam82 recombinant protein protects against E. maxima and augments humoral and cell-mediated immunity [PubMed: 20178868]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010833 .

obo:VO_0002379 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000620 , obo:VO_0001466 , obo:VO_0001501 , obo:VO_0001523 .

obo:VO_0015925 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 20" ;
  rdfs:subClassOf obo:VO_0015632 , obo:VO_0015692 , obo:VO_0016029 .

obo:VO_0000761 a rdfs:Class ;
  rdfs:label "malaria vaccine" ;
  rdfs:comment "Plasmodium vaccine is a vaccine that prevents against Plasmodium species causing malaria. It is made from antigens arising from any of the four strains of Plasmodium which cause malaria in humans, or from P. berghei which causes malaria in rodents." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0016609 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Twinrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0016561 , obo:VO_0016614 .

obo:VO_0020895 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Inflexal]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0004596 a rdfs:Class ;
  rdfs:label "SHIV DNA vaccine encoding env and gag" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0015762 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015583 , obo:VO_0015819 .

obo:VO_0001806 a rdfs:Class ;
  rdfs:label "Pseudorabies Modified Live Virus Vaccine (USDA: 1891.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000750 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0018579 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0018578 , obo:VO_0018682 .

obo:VO_0002245 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47K1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002410 , obo:VO_0007748 .

obo:VO_0016779 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0016721 .

obo:OPL_0000057 a rdfs:Class ;
  rdfs:label "trophozoite stage" ;
  rdfs:comment "A parasite lifecycle stage of some protozoan parasites that is a non-reproductive, feeding and growing stage." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0002299 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002479 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0002738 a rdfs:Class ;
  rdfs:label "UL23 from Pseudorabies virus" ;
  rdfs:comment "A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001442 .

obo:VO_0018908 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:DOID_3908 a rdfs:Class ;
  rdfs:label "lung non-small cell carcinoma"@en ;
  rdfs:comment "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma."@en ;
  rdfs:subClassOf obo:DOID_3905 .

obo:VO_0004887 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0004886 .

obo:VO_0010637 a rdfs:Class ;
  rdfs:label "Rubella virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Rubella virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003549 .

obo:VO_0001126 a rdfs:Class ;
  rdfs:label "Agriflu" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0010415 .

obo:VO_0004742 a rdfs:Class ;
  rdfs:label "FP-IBDV-VP2 vaccine" ;
  rdfs:subClassOf obo:VO_0001497 .

obo:VO_0019311 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020008 .

obo:VO_0019942 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Afluria 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020302 .

obo:VO_0002364 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002368 .

obo:VO_0017503 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension [T-Immun Immuno]" ;
  rdfs:subClassOf obo:VO_0017483 , obo:VO_0017502 .

obo:VO_0003905 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Flublok Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003903 .

obo:VO_0003174 a rdfs:Class ;
  rdfs:label "DTP-ActHIB vaccine" ;
  rdfs:comment "A vaccine used to prevent diphtheria, tetanus, pertussis, and Haemophilus type B infections." ;
  rdfs:subClassOf obo:VO_0000942 .

obo:VO_0020487 a rdfs:Class ;
  rdfs:label "Fluzone Intradermal 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003440 , obo:VO_0010417 .

obo:VO_0005477 a rdfs:Class ;
  rdfs:label "Giardia spp. protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0000209 a rdfs:Class ;
  rdfs:label "pHIS64 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0005116 a rdfs:Class ;
  rdfs:label "Ad5.MERS-S1 vaccine" ;
  rdfs:comment "A MERS recombinant vector vaccine made of a recombinant adenoviral vector encoding the  the S1 extracellular domain of S protein" ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0010961 a rdfs:Class ;
  rdfs:label "GP from Lake Victoria marburgvirus" ;
  rdfs:comment "Study developed replication-competent vaccines against EBOV and MARV based on attenuated recombinant vesicular stomatitis virus vectors expressing either the EBOV glycoprotein or MARV glycoprotein from Lake Victoria marburgvirus - Musoke. A single intramuscular injection of the EBOV or MARV vaccine elicited completely protective immune responses in nonhuman primates against lethal EBOV or MARV challenges [PubMed: 15937495]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010769 .

obo:VO_0001874 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calicivirus Modified Live Virus Vaccine (USDA: 16C1.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001220 , obo:VO_0002440 , obo:VO_0007748 .

obo:VO_0016157 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0002515 a rdfs:Class ;
  rdfs:label "Leishmania infantum gene" ;
  rdfs:comment "A protozoan gene that is from Leishmania infantum." ;
  rdfs:subClassOf obo:VO_0000174 .

obo:VO_0016864 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 10 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016819 .

obo:VO_0021150 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.12 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 31 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 33 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 45 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 52 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 58 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.06 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 .

obo:VO_0010334 a rdfs:Class ;
  rdfs:label "ABRYSVO (STN 125768) vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000753 .

obo:VO_0019102 a rdfs:Class ;
  rdfs:label "delayed release oral tablet" ;
  rdfs:subClassOf obo:VO_0018847 .

obo:VO_0019316 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Afluria 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020298 .

obo:VO_0000642 a rdfs:Class ;
  rdfs:label "influenza virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with influenza virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0021084 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0001214 , obo:VO_0010447 .

obo:VO_0011329 a rdfs:Class ;
  rdfs:label "ELI-Ag1" ;
  rdfs:comment "ELI-Antigen 1 (ELI-Ag1) was tested for its protective capacity in BALB/c mice against intraperitoneal challenge with 2500 arthroconidia of this dimorphic fungus and was found to be highly protective [PubMed: 14505918]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010853 .

obo:VO_0004897 a rdfs:Class ;
  rdfs:label "coronavirus vaccine" ;
  rdfs:comment "A vaccine against coronavirus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0018543 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.02 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0018539 .

obo:VO_0020974 a rdfs:Class ;
  rdfs:label "Influenza Virus Fragmented, Inactivated, Strain B / Phuket / 3073/2013 0.0075 MG/ML" ;
  rdfs:subClassOf obo:VO_0020973 .

obo:VO_0002948 a rdfs:Class ;
  rdfs:label "Yersinia ruckeri aroA mutant vaccine" ;
  rdfs:comment "An aroA mutant is highly attenuated in rainbow trout and induces significant protection from challenge with wild type Y. ruckeri" ;
  rdfs:subClassOf obo:VO_0001035 .

obo:VO_0004541 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus DNA vaccine pClfaSrtD13" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002502 .

obo:VO_0004463 a rdfs:Class ;
  rdfs:label "Schistosoma mansoni DNA vaccine pcDNA/GPXbb encoding glutathione-S-peroxidase, GPX" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0003046 .

obo:VO_0002959 a rdfs:Class ;
  rdfs:label "Feline immunodeficiency virus ORF-A mutant vaccine" ;
  rdfs:comment "Feline immunodeficiency virus (FIV) made defective in the accessory gene ORF-A were previously shown to be greatly attenuated in its ability to replicate in lymphocytes but to grow normally or near normally in other cell types. 3/9 vaccinees (cats) showed no evidence of the challenge virus over a 15-month observation period. In the other vaccinees, the challenge virus was predominant for various periods of time, but pre-existing viral loads and CD4 lymphocyte counts were either unaffected or altered only marginally and transiently" ;
  rdfs:subClassOf obo:VO_0001508 .

obo:BFO_0000003 a rdfs:Class ;
  rdfs:label "occurrent"@en ;
  rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:VO_0003584 a rdfs:Class ;
  rdfs:label "Fluzone 2016-2017 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 , obo:VO_0010432 .

obo:VO_0016554 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000745 , obo:VO_0001214 .

obo:VO_0002436 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Vaccine" ;
  rdfs:subClassOf obo:VO_0000389 , obo:VO_0002440 .

obo:VO_0002110 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.T0)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002408 , obo:VO_0007748 .

obo:VO_0000495 a rdfs:Class ;
  rdfs:label "induction of adaptive immune response to antigen" ;
  rdfs:comment "induction of adaptive immune response to antigen is an active immunization process that results in induction of adaptive immune response to some antigens, for example, in a vaccine." ;
  rdfs:subClassOf obo:VO_0000491 .

obo:VO_0018213 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus 1000 UNT / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2000 PFU [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018247 .

obo:NCBITaxon_10240 a rdfs:Class ;
  rdfs:label "Poxviridae" ;
  rdfs:subClassOf obo:NCBITaxon_2732525 .

obo:VO_0011196 a rdfs:Class ;
  rdfs:label "NcSAG1" ;
  rdfs:comment "NcSAG1 and NcSRS2, the two major immunodominant tachyzoite surface antigens of the apicomplexan parasite Neospora caninum, were investigated for their potential as vaccine candidates in mice. Results suggest that a combined DNA/recombinant antigen-vaccine, based on NcSAG1 and NcSRS2, respectively, exhibited a highly significant protective effect against experimentally induced cerebral neosporosis in mice [PubMed: 12741509]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0011538 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei DNA vaccine encoding Flagellin protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012175 .

obo:VO_0015911 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015626 , obo:VO_0015763 , obo:VO_0016022 .

obo:VO_0019366 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen (isoform L), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform M), recombinant 0.01 MG/ML / hepatitis B surface antigen (isoform S), recombinant 0.01 MG/ML Injection [Prehevbrio]" ;
  rdfs:subClassOf obo:VO_0019365 , obo:VO_0019515 .

obo:VO_0020358 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a 10000000000 UNT [Vivotif]" ;
  rdfs:subClassOf obo:VO_0003353 , obo:VO_0003446 .

obo:VO_0001091 a rdfs:Class ;
  rdfs:label "Poulvac FluFend I AI H5N3 RG vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000461 , obo:VO_0003143 .

obo:VO_0015490 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003421 , obo:VO_0003423 .

obo:VO_0002555 a rdfs:Class ;
  rdfs:label "dnt from Bordetella bronchiseptica" ;
  rdfs:comment "A dnt mutant in Bordetella bronchiseptica was attenuated and provides protection in guinea pigs against intranasal challenge with strain L3" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001407 .

obo:VO_0007371 a rdfs:Class ;
  rdfs:label "dendritic cell-gp100-MART-1 Antigen vaccine" ;
  rdfs:comment "An autologous dendritic cells vaccine with antineoplastic property. Dendritic cells harvested from cancer patients are pulsed with human gp100 melanoma antigen and MART-1 (melanoma antigen recognized by T-cells) antigen; both antigens are up-regulated in melanomas. Vaccination with this vaccine may elicit the host immune response against MART-1 or gp100 expressing cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0001839 a rdfs:Class ;
  rdfs:label "Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 49A5.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002452 , obo:VO_0007748 , obo:VO_0010475 .

obo:NCBITaxon_836 a rdfs:Class ;
  rdfs:label "Porphyromonas" ;
  rdfs:subClassOf obo:NCBITaxon_976 .

obo:VO_0018572 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension [Stamaril] Box of 1" ;
  rdfs:subClassOf obo:VO_0018571 , obo:VO_0018576 , obo:VO_0018763 .

obo:VO_0018048 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Vaccine 35000 PFU/ML / Rubella virus 1400 PFU/ML / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018137 .

obo:NCBITaxon_9611 a rdfs:Class ;
  rdfs:label "Canis" ;
  rdfs:subClassOf obo:NCBITaxon_9608 .

obo:VO_0010147 a rdfs:Class ;
  rdfs:label "Chikungunya, live attenuated vaccine, 0.5 mL, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0001220 , obo:VO_0002785 .

obo:VO_0000535 a rdfs:Class ;
  rdfs:label "recombinant Salmonella typhimurium secreting Mycobacterium tuberculosis ESAT-6 vaccine" ;
  rdfs:subClassOf obo:VO_0000077 , obo:VO_0000484 .

obo:VO_0020982 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigen, strain A / Victoria / 361/2011 H3N2 - Derived Strain Used Ivr-165" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010329 , obo:VO_0010415 .

obo:VO_0017437 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.02 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017435 , obo:VO_0017445 .

obo:VO_0004309 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine HA DNA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0019838 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0017612 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0017611 , obo:VO_0017629 .

obo:VO_0016870 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] Box of 25 by Sanofi" ;
  rdfs:subClassOf obo:VO_0016810 .

obo:VO_0004565 a rdfs:Class ;
  rdfs:label "Laryngotracheitis DNA vaccine encoding gB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001488 .

obo:VO_0007398 a rdfs:Class ;
  rdfs:label "Mammaglobin-A DNA Vaccine" ;
  rdfs:comment "A cancer vaccine containing a plasmid encoding the mammaglobin-A gene with potential immunostimulating and antineoplastic activities. Upon administration, mammaglobin-A DNA vaccine may induce both humoral and cytotoxic T lymphocyte (CTL) immune responses against tumor cells that express mammaglobin-A, which may result in decreased tumor growth. The 10 kiloDalton (kD) glycoprotein mammglobin-A is expressed in over 80% of human breast cancers." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 , obo:VO_0007660 .

obo:OPL_0000257 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum hepatic trophozoite" ;
  rdfs:comment "A Plasmodium falciparum trophozoite that is found in hepatocytes of a human host. It is a feeding stage with a single nucleus" ;
  rdfs:subClassOf obo:OPL_0000146 , obo:OPL_0000284 .

obo:GO_0019814 a rdfs:Class ;
  rdfs:label "immunoglobulin complex" ;
  rdfs:comment "A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ;
  rdfs:subClassOf obo:GO_0032991 .

obo:NCBITaxon_693997 a rdfs:Class ;
  rdfs:label "Alphacoronavirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_2501931 .

obo:VO_0002476 a rdfs:Class ;
  rdfs:label "Rabies vaccine-Ehrlichia Risticii Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0000650 , obo:VO_0001472 , obo:VO_0003550 .

obo:VO_0000153 a rdfs:Class ;
  rdfs:label "toxoid vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a toxoid vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0002804 a rdfs:Class ;
  rdfs:label "obsolete Bordetella bronchiseptica bscN and cyaA double mutant vaccine" ;
  rdfs:comment "A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 x 105 CFU of RB50, the B. Bronchiseptica parent strain." .

obo:VO_0000388 a rdfs:Class ;
  rdfs:label "E. coli LT toxin derived vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant that is derived from E. coli heat labile toxin LT." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0017972 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0017943 , obo:VO_0017959 .

obo:VO_0019478 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.02 MG/ML / tetanus toxoid vaccine, inactivated 0.048 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0019471 .

obo:VO_0015936 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 20" ;
  rdfs:subClassOf obo:VO_0015636 , obo:VO_0016037 .

obo:VO_0007548 a rdfs:Class ;
  rdfs:label "MAGE-A1/MAGE-A3/NY-ESO-1 peptide vaccine" ;
  rdfs:comment "A cancer vaccine comprised of synthetic peptides derived from human melanoma antigen A1 (MAGE-A1), human melanoma antigen A3 (MAGE-A3) and cancer-testis antigen NY-ESO-1 with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-A1/MAGE-A3/NY-ESO-1 peptides vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-A1, MAGE-A3 and NY-ESO-1, resulting in tumor cell lysis. The MAGE-A1, MAGE-A3, and NY-ESO-1 tumor-associated antigens (TAAS) are overexpressed by a variety of cancer cell types." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0000620 a rdfs:Class ;
  rdfs:label "Pasteurella multocida vaccine" ;
  rdfs:comment "Vaccine that protects against Pasteurella multocida infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0003320 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 17F vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003221 .

obo:VO_0007167 a rdfs:Class ;
  rdfs:label "Rilimogene-galvacirepvec Vaccine" ;
  rdfs:comment "A vaccine formulation consisting of recombinant vaccinia virus encoding prostate specific antigen (PSA) and recombinant vaccinia virus encoding three co-stimulatory molecule transgenes B7.1, ICAM-1, and LFA-3 (TRICOM). Vaccination with PSA in combination with TRICOM may enhance antigen presentation, resulting in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells expressing PSA." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0001933 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Haemophilus somnus-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4489.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002490 .

obo:VO_0005037 a rdfs:Class ;
  rdfs:label "pET11d DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pET11d.  This plasmid is 5674 base pairs in length and contains an ampicillin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003632 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2016-2017 Formula 0.5 ML Injection" ;
  rdfs:comment "RXN STRENGTH: 0.03 MG/ML (expressed as influenza A virus A/California/7/2009 (H1N1) antigen) / 0.03 MG/ML (expressed as influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen) / 0.03 MG/ML (expressed as influenza B virus B/Brisbane/60/2008 antigen) / 0.03 MG/ML (expressed as influenza B virus B/Phuket/3073/2013 antigen)" ;
  rdfs:subClassOf obo:VO_0003631 .

obo:VO_0010154 a rdfs:Class ;
  rdfs:label "hepatitis B vaccine, adult dosage" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010439 .

obo:VO_0019764 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.0857 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.0857 MG/ML [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:VO_0002438 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci-Rabies Vaccine" ;
  rdfs:subClassOf obo:VO_0000650 , obo:VO_0002437 .

obo:VO_0021111 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0003692 a rdfs:Class ;
  rdfs:label "Fluvirin 2017-2018 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003691 .

obo:VO_0017514 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0017506 .

obo:VO_0016467 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Mevita" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0018392 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe [Pneumopur]" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0017652 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Clostet]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0007667 a rdfs:Class ;
  rdfs:label "GVAX leukemia vaccine" ;
  rdfs:comment "A cancer vaccine that uses irradiated, adenovirus transduced autologous myeloblasts to secrete granulocyte-macrophage colony-stimulating factor (GVAX) early after allogeneic hematopoietic stem cell transplantation (HSCT) to induce potent immune responses. The vaccine may prevent advanced myelodysplastic syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), or acute myeloid leukemia (AML) from relapsing after stem cell transplant. The patients own cancer cells are engineered to produce a protein called GM-CSF, which can be effective in stimulating a powerful immune response specific to that cancer. " ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0020913 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0015745 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 250" ;
  rdfs:subClassOf obo:VO_0015495 , obo:VO_0015810 .

obo:VO_0010876 a rdfs:Class ;
  rdfs:label "V antigen" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0000067 a rdfs:Class ;
  rdfs:label "Kinrix vaccine" ;
  rdfs:comment "Product Name: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0016034 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0003426 , obo:VO_0015787 .

obo:VO_0016477 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Haematogmbh" ;
  rdfs:subClassOf obo:VO_0015977 .

obo:VO_0002891 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine" ;
  rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" .

obo:VO_0019914 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0020482 a rdfs:Class ;
  rdfs:label "Fluzone 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 , obo:VO_0010417 .

obo:VO_0017383 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Adt Booster]" ;
  rdfs:subClassOf obo:VO_0017670 .

obo:VO_0003730 a rdfs:Class ;
  rdfs:label "Afluria 2017-2018 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003728 .

obo:VO_0017699 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] Box of 20" ;
  rdfs:subClassOf obo:VO_0017696 , obo:VO_0017705 , obo:VO_0017749 .

obo:VO_0016315 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015930 .

obo:VO_0016244 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [VACCIN GENHEVAC B] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015912 .

obo:VO_0003314 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 10A vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003959 .

obo:NCBITaxon_7995 a rdfs:Class ;
  rdfs:label "Siluriformes" ;
  rdfs:subClassOf obo:NCBITaxon_186625 .

obo:VO_0001803 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine (USDA: 19S1.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001511 , obo:VO_0007748 .

obo:VO_0002632 a rdfs:Class ;
  rdfs:label "fliD from Salmonella Typhimurium" ;
  rdfs:comment "A guaBA, clpP, and fliD mutant (CVD 1923) is attenuated in mice after oral immunization. This mutant is also protective, with a vaccine efficacy of 80% in mice against wild type challenge from Salmonella Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0003472 a rdfs:Class ;
  rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010303 , obo:VO_0010415 .

obo:VO_0001326 a rdfs:Class ;
  rdfs:label "Brucella abortus subunit vaccine using Omp16" ;
  rdfs:subClassOf obo:VO_0001221 .

obo:NCBITaxon_9608 a rdfs:Class ;
  rdfs:label "Canidae" ;
  rdfs:subClassOf obo:NCBITaxon_379584 .

obo:NCBITaxon_3052303 a rdfs:Class ;
  rdfs:label "Mammarenavirus choriomeningitidis" ;
  rdfs:subClassOf obo:NCBITaxon_1653394 .

obo:VO_0018805 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML Injectable Suspension [Cervarix]" ;
  rdfs:subClassOf obo:VO_0018804 .

obo:NCBITaxon_38345 a rdfs:Class ;
  rdfs:label "Leptospira kirschneri serovar Grippotyphosa" ;
  rdfs:subClassOf obo:NCBITaxon_171 .

obo:NCBITaxon_180255 a rdfs:Class ;
  rdfs:label "Iltovirus" ;
  rdfs:subClassOf obo:NCBITaxon_10293 .

obo:VO_0018500 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018465 .

obo:VO_0001727 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium Live Culture Vaccine (USDA: 19C1.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0002507 , obo:VO_0007748 .

obo:VO_0005806 a rdfs:Class ;
  rdfs:label "p52(-)/p36(-) GAP vaccine" ;
  rdfs:comment "A Live attenuated vaccine p52(-)/p36(-) GAP that immunizes against Plasmodium falciparum sporozoite." ;
  rdfs:subClassOf obo:VO_0000087 , obo:VO_0000455 .

obo:VO_0010323 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide vaccine" ;
  rdfs:subClassOf obo:VO_0012185 .

obo:VO_0012385 a rdfs:Class ;
  rdfs:label "OspB" ;
  rdfs:comment "Mice immunized with recombinant OspB protein were protected from challenge with Borrelia burgdorferi [PubMed: 8168958]." ;
  rdfs:subClassOf obo:VO_0012368 .

obo:VO_0018690 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML Oral Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018687 .

obo:VO_0011136 a rdfs:Class ;
  rdfs:label "M1 from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ;
  rdfs:comment "Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later.  The mice immunized with M1 plasmid survived 25% with five immunizations.  The mixture of M1 and NP plasmids protected 95% of the mice against the homologous virus, and 80% of the mice against a challenge with heterologous H1N1 (PR8) virus [PubMed: 19067149]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0020180 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (human), inactivated Injection" ;
  rdfs:subClassOf obo:VO_0003857 .

obo:VO_0018721 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0018719 , obo:VO_0018720 .

obo:VO_0019724 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Fluvirin 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003681 , obo:VO_0019723 .

obo:VO_0019330 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.12 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 31 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 33 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 45 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 52 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 58 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.06 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 .

obo:VO_0016274 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Veron" ;
  rdfs:subClassOf obo:VO_0015923 .

obo:VO_0007477 a rdfs:Class ;
  rdfs:label "GITRL RNA-transfected autologous dendritic cell vaccine" ;
  rdfs:comment "An autologous dendritic cell (DC) cancer vaccine with GITRL RNA-transfected that has potential immunostimulatory activity. " ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0002090 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002413 , obo:VO_0007748 .

obo:VO_0004329 a rdfs:Class ;
  rdfs:label "Human papillomavirus DNA vaccine Pe7(pcDNA3-Sig/sE7/LAMP) encoding E7" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000667 .

obo:VO_0018924 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen" ;
  rdfs:subClassOf obo:VO_0015085 .

obo:VO_0018532 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension [Ixiaro] by Valneva" ;
  rdfs:subClassOf obo:VO_0018529 .

obo:VO_0000467 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus phage lysate vaccine" ;
  rdfs:comment "a S. aureus vaccine that uses the bacterial phage lysate as the protective antigen. " ;
  rdfs:subClassOf obo:VO_0002502 .

obo:VO_0018546 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, Human papillomavirus type 16 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML Injectable Suspension [Cervarix]" ;
  rdfs:subClassOf obo:VO_0018545 , obo:VO_0018652 .

obo:VO_0002229 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002403 , obo:VO_0007748 .

obo:DOID_170 a rdfs:Class ;
  rdfs:label "endocrine gland cancer"@en ;
  rdfs:comment "An organ system cancer located_in endocrine system that is characterized by uncontrolled cellular proliferation of the hormone producing glands of the endocrine system."@en ;
  rdfs:subClassOf obo:DOID_0050686 .

obo:VO_0000738 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Pertussis vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000732 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0003101 a rdfs:Class ;
  rdfs:label "Cholera vaccine, USP" ;
  rdfs:comment "An active immunization against cholera, indicated only for individuals traveling to or residing in countries where cholera is endemic or epidemic." ;
  rdfs:subClassOf obo:VO_0006004 .

obo:VO_0005156 a rdfs:Class ;
  rdfs:label "CoV2 SAM vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine that has a lipid nanoparticle (LNP) platform and Spike protein antigen" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0019730 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/11/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Delaware/55/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML / influenza B virus B/Singapore/WUH4618/2021 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020335 .

obo:VO_0020234 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain 500000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0020229 .

obo:VO_0017814 a rdfs:Class ;
  rdfs:label "Haemophilus B Conjugate Vaccine / meningococcal group C polysaccharide" ;
  rdfs:subClassOf obo:VO_0000053 , obo:VO_0000195 .

obo:VO_0005441 a rdfs:Class ;
  rdfs:label "licensed human cytomegalovirus immune globulin passive vaccine, intravenous" ;
  rdfs:subClassOf obo:VO_0005445 .

obo:VO_0017920 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injectable Solution [Nimenrix]" ;
  rdfs:subClassOf obo:VO_0003080 , obo:VO_0017819 .

obo:VO_0005466 a rdfs:Class ;
  rdfs:label "tetanus and diphtheria toxoids, adsorbed, preservative free, for adult use (2 Lf of tetanus toxoid and 2 Lf of diphtheria toxoid)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000714 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0018695 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 700000 PFU Powder for Oral Suspension [Rotarix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018694 , obo:VO_0018697 .

obo:VO_0005196 a rdfs:Class ;
  rdfs:label "VXA-CoV2-1 vaccine" ;
  rdfs:comment "A SARS-CoV-2 adenoviral vector-based oral vaccine by Vaxart expressing a SARS-CoV-2 antigen and dsRNA adjuvant" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:VO_0010008 a rdfs:Class ;
  rdfs:label "inactivated vaccine role" ;
  rdfs:comment "Vaccine role that is characteristic of an inactivated vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0010990 a rdfs:Class ;
  rdfs:label "C4424" ;
  rdfs:comment "Active immunization of BALB/c mice with C4424 antigen in Freund's adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0018602 a rdfs:Class ;
  rdfs:label "Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 2220000 UNT" ;
  rdfs:subClassOf obo:VO_0004824 .

obo:VO_0005392 a rdfs:Class ;
  rdfs:label "ACM-001 vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by ACM Biolabs." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0002688 a rdfs:Class ;
  rdfs:label "sodA from Yersinia enterocolitica" ;
  rdfs:comment "A sodA mutant in Yersinia enterocolitica was highly attenuated and mice immunized with a single oral dose of the mutant strain were protected against a lethal oral-challenge infection with wild-type Y. enterocolitica" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001425 .

obo:VO_0019695 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0005141 a rdfs:Class ;
  rdfs:label "CoronaVac vaccine" ;
  rdfs:comment "A SARS-CoV-2 whole virus vaccine made from a purified inactivated SARS-CoV-2 virus." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0020553 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluarix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020552 .

obo:VO_0002920 a rdfs:Class ;
  rdfs:label "Shigella flexneri 2a strain CVD 1203 vaccine" ;
  rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ;
  rdfs:subClassOf obo:VO_0000680 .

obo:VO_0000337 a rdfs:Class ;
  rdfs:label "pWRG1644 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0010070 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi CRP" ;
  rdfs:comment "A CRP protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0000928 a rdfs:Class ;
  rdfs:label "Raboral vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000645 , obo:VO_0000649 , obo:VO_0000650 .

obo:VO_0002324 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome-Parvovirus Reproductive Form, Modified Live & Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4P19.20)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002473 , obo:VO_0007748 .

obo:VO_0015853 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] by Sanofi" ;
  rdfs:subClassOf obo:VO_0015647 .

obo:VO_0018583 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML Oral Suspension" ;
  rdfs:subClassOf obo:VO_0018687 .

obo:VO_0005476 a rdfs:Class ;
  rdfs:label "Nanostructured Lipid Carrier (NLC) vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant is a small molecule adjuvant that induces Th1-based immune response and is designed for use with self-amplifying RNA antigens." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017670 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 .

obo:NCBITaxon_5833 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum" ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0001636 a rdfs:Class ;
  rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000961 , obo:VO_0007748 .

obo:VO_0010127 a rdfs:Class ;
  rdfs:label "obsolete Historical diphtheria and tetanus toxoids and acellular pertussis, poliovirus, Haemophilus b conjugate and hepatitis B (recombinant) vaccine." .

obo:VO_0002285 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.21)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002431 , obo:VO_0007748 .

obo:VO_0020571 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Inflexal] Box of 10 by Crucell" ;
  rdfs:subClassOf obo:VO_0020570 .

obo:VO_0005179 a rdfs:Class ;
  rdfs:label "lipid nanoparticle vector" ;
  rdfs:comment "A nanoparticle vector composed of lipids." ;
  rdfs:subClassOf obo:VO_0005180 .

obo:VO_0003205 a rdfs:Class ;
  rdfs:label "Bordetella pertussis pertactin vaccine, inactivated 0.005 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003199 .

obo:VO_0020743 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 120 MG [Pacis]" ;
  rdfs:subClassOf obo:VO_0020742 .

obo:VO_0011009 a rdfs:Class ;
  rdfs:label "YdeN" ;
  rdfs:comment "Using a mouse plague model, YPO3047 (ydeN) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0003541 a rdfs:Class ;
  rdfs:label "Reoviridae vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Reoviridae." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0004688 a rdfs:Class ;
  rdfs:label "M.S-Helicobacter pylori-opm26 vaccine" ;
  rdfs:subClassOf obo:VO_0012181 .

obo:VO_0004933 a rdfs:Class ;
  rdfs:label "human age 1 to 2 months at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0004002 a rdfs:Class ;
  rdfs:label "Brucella melitensis omp31 mutant vaccine" ;
  rdfs:comment "A omp31 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice" ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0020791 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 500000000 CFU Injection [Oncotice Bcg]" ;
  rdfs:subClassOf obo:VO_0020789 , obo:VO_0020790 , obo:VO_0020808 .

obo:VO_0010958 a rdfs:Class ;
  rdfs:label "MSP1 from P. falciparum" ;
  rdfs:comment "Aotus monkeys were challenged with the virulent Vietnam Oak Knoll (FVO) strain of P. falciparum.  Vaccination of A. nancymai with yMSP1(19) induced protective immune responses.  Both of the A. nancymai vaccinated with yMSP1(19) self-resolved an otherwise lethal infection [PubMed: 8529111]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0019983 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:NCBITaxon_10927 a rdfs:Class ;
  rdfs:label "Bovine rotavirus" ;
  rdfs:subClassOf obo:NCBITaxon_10912 .

obo:VO_0002144 a rdfs:Class ;
  rdfs:label "Marek's Disease-Newcastle Disease Serotypes 1 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 16N1.R1)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002447 , obo:VO_0007748 .

obo:VO_0002516 a rdfs:Class ;
  rdfs:label "apxIA from Actinobacillus pleuropneumoniae" ;
  rdfs:comment "The mutant strain, with deletion of apxIA gene, obtained in this study offered a level of cross-serovar protection against A. pleuropneumoniae infection in mice and pigs (Reference: PMID: 16930871)." ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001384 .

obo:VO_0020380 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Injectable Solution [Typherix]" ;
  rdfs:subClassOf obo:VO_0010744 , obo:VO_0020278 .

obo:VO_0000484 a rdfs:Class ;
  rdfs:label "recombinant vector vaccine" ;
  rdfs:comment "A vaccine that uses a modified virus or bacterium as the vector to deliver vaccine antigen(s) to the cells of the host body." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0005505 .

obo:VO_0020132 a rdfs:Class ;
  rdfs:label "mumps virus vaccine live, Jeryl Lynn strain / rubella virus vaccine live (Wistar RA 27-3 strain) Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0001220 , obo:VO_0003418 .

obo:VO_0010068 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii SSP2" ;
  rdfs:comment "A SSP2 protein that is part of Plasmodium yoelii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015474 .

obo:VO_0018037 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0018022 .

obo:VO_0004677 a rdfs:Class ;
  rdfs:label "Schmidt-Ruppin Rous sarcoma virus-H7 (H7N7) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0005026 a rdfs:Class ;
  rdfs:label "pMASIA-tgD DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pMASIA-tgD.  This plasmid is based off of pMASIA and contains a CMV promoter and kanamycin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0003220 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 15B vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0000377 a rdfs:Class ;
  rdfs:label "sublingual route" ;
  rdfs:comment "An oral route of administration that is underneath the tongue." ;
  rdfs:seeAlso <http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38300> ;
  rdfs:subClassOf obo:VO_0000886 .

obo:VO_0016384 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 3 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015946 .

obo:VO_0019805 a rdfs:Class ;
  rdfs:label "influenza A virus A/Idaho/07/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Indiana/08/2018 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Iowa/06/2017 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020332 .

obo:VO_0002875 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Gallinarum cbiA/cobS mutant vaccine" ;
  rdfs:comment "A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis" .

obo:VO_0000164 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis gene" ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0015665 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015594 .

obo:VO_0017158 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Pediacel] Box of 10" ;
  rdfs:subClassOf obo:VO_0017157 , obo:VO_0017183 , obo:VO_0017614 .

obo:VO_0015944 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015638 , obo:VO_0015718 , obo:VO_0016042 .

obo:VO_0004773 a rdfs:Class ;
  rdfs:label "ALVAC- CDV-H/F vaccine" ;
  rdfs:subClassOf obo:VO_0012178 .

obo:VO_0005496 a rdfs:Class ;
  rdfs:label "esophageal cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against esophageal cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0016954 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017411 .

obo:VO_0016277 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015924 .

obo:VO_0004144 a rdfs:Class ;
  rdfs:label "E. coli heat-labile enterotoxin B-subunit (LB-T) vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0020839 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Fluad]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0004794 a rdfs:Class ;
  rdfs:label "NYVAC-Pf7 vaccine" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0020282 a rdfs:Class ;
  rdfs:label "varicella zoster virus glycoprotein E Injection [Shingrix]" ;
  rdfs:subClassOf obo:VO_0003317 , obo:VO_0020281 .

obo:VO_0007026 a rdfs:Class ;
  rdfs:label "NY-ESO-1/GLA-SE vaccine ID-G305AmN" ;
  rdfs:comment "A cancer vaccine composed of a recombinant form of the tumor antigen NY-ESO-1 and glucopyranosyl lipid adjuvant (GLA)-stable emulsion (GLA-SE), with potential antineoplastic and immunomodulating activities. Upon intramuscular injection, the adjuvant portion of the NY-ESO-1/GLA-SE vaccine ID-G30 binds to toll-like receptor subtype 4 (TLR-4) expressed on dendritic cells (DCs), monocytes, macrophages and B cells. The activated DCs present the NY-ESO-1 antigen to Th1 CD4 T-lymphocytes. This leads to the induction of cytotoxic T lymphocytes (CTLs) and the killing of NY-ESO-1-expressing tumor cells. This vaccine also induces specific antibody responses and increases the production of inflammatory cytokines." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0005484 , obo:VO_0005486 , obo:VO_0005493 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0019594 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Nasal Spray [Flumist Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0003807 , obo:VO_0019592 .

obo:NCBITaxon_33213 a rdfs:Class ;
  rdfs:label "Bilateria" ;
  rdfs:subClassOf obo:NCBITaxon_33154 .

obo:VO_0018326 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0018318 .

obo:VO_0020072 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.09 MG/ML [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0017883 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.004 MG" ;
  rdfs:subClassOf obo:VO_0015070 .

obo:VO_0010908 a rdfs:Class ;
  rdfs:label "RplL" ;
  rdfs:comment "Study was designed to evaluate the immunogenicity and the protective efficacy of a divalent fusion DNA vaccine encoding both the Brucella abortus L7/L12 protein (ribosomal protein, rplL) and Omp16 protein (outer membrane lipoprotein). This divalent DNA vaccine induced a significant level of protection against challenge with the virulent B. abortus in BALB/c mice [PubMed: 16622210]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0006100 a rdfs:Class ;
  rdfs:label "SLA-Alum vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant of a synthetic TLR4 agonist and aluminum salt." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0001553 a rdfs:Class ;
  rdfs:label "Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0007748 .

obo:VO_0010348 a rdfs:Class ;
  rdfs:label "IXCHIQ vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002785 .

obo:VO_0000287 a rdfs:Class ;
  rdfs:label "vaccine-induced immune response" ;
  rdfs:comment "An immune system process that is realized in the calibrated response of the recipient to a vaccine." ;
  rdfs:subClassOf obo:VO_0000288 .

obo:VO_0011282 a rdfs:Class ;
  rdfs:label "SMT" ;
  rdfs:comment "Upon challenge with L. infantum, C57BL/6 mice immunized with SMT formulated in MPL-SE adjuvant showed significantly lower parasite burdens in both spleens and livers compared with non-immunized mice or mice injected with adjuvant alone [PubMed: 17804125]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010836 .

obo:VO_0015756 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 50" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015816 .

obo:VO_0004886 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0010464 a rdfs:Class ;
  rdfs:label "cell-mediated immune marker" ;
  rdfs:comment "An immune biomarker that indicates a cell-mediated immune response." ;
  rdfs:subClassOf obo:OPMI_0000446 .

obo:VO_0016730 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 UNT/ML Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0016715 , obo:VO_0016735 .

obo:VO_0017727 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0017713 , obo:VO_0017788 .

obo:VO_0000401 a rdfs:Class ;
  rdfs:label "prime-boost vaccine with DNA vaccine priming" ;
  rdfs:comment "A prime-boost vaccine that contains one DNA vaccine for priming and at least one other vaccine for boosting. " ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000400 .

obo:VO_0018171 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0018166 .

obo:VO_0017210 a rdfs:Class ;
  rdfs:label "1 ML tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017205 , obo:VO_0017536 .

obo:DOID_1542 a rdfs:Class ;
  rdfs:label "head and neck carcinoma"@en ;
  rdfs:comment "A head and neck cancer that has_material_basis_in epithelial cells and is located in the upper aerodigestive tract, including the lip, oral cavity (mouth), nasal cavity, paranasal sinuses, pharynx, and larynx."@en ;
  rdfs:subClassOf obo:DOID_11934 , obo:DOID_305 .

obo:VO_0003804 a rdfs:Class ;
  rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen" ;
  rdfs:comment "CUI: C4026651" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0001445 a rdfs:Class ;
  rdfs:label "Simian Immunodeficiency Virus gene" ;
  rdfs:comment "A viral gene that is from Simian Immunodeficiency Virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0004077 a rdfs:Class ;
  rdfs:label "BoNT/B(Hc) vaccine" ;
  rdfs:subClassOf obo:VO_0012187 .

obo:VO_0002374 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000658 , obo:VO_0001466 , obo:VO_0001503 .

obo:VO_0010075 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi Tc24" ;
  rdfs:comment "A Tc24 protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0003115 a rdfs:Class ;
  rdfs:label "Optaflu vaccine" ;
  rdfs:comment "A vaccine against flu (influenza) in adults, especially in those who run an increased risk of experiencing associated complications in case they fall ill with flu." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0002496 , obo:VO_0010415 .

obo:VO_0000261 a rdfs:Class ;
  rdfs:label "usage of steroid" ;
  rdfs:subClassOf obo:VO_0000207 .

obo:VO_0001766 a rdfs:Class ;
  rdfs:label "Rabies Live Canarypox Vector Vaccine (USDA: 1901.R6)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0007307 a rdfs:Class ;
  rdfs:label "autologous melanoma Lysate/NY-ESO-1-pulsed autologous dendritic cell vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with both a lysate from autologous melanoma cells containing tumor associated antigens (TAAs) and a synthetic peptide derived from the tumor associated antigen human cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate/NY-ESO-1-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody-mediated immune responses against melanoma cells, which may result in melanoma cell lysis. NY-ESO-1 is expressed in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0016158 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Europharma" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0001223 a rdfs:Class ;
  rdfs:label "Brucella melitensis subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000709 .

obo:VO_0002411 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ;
  rdfs:subClassOf obo:VO_0002412 .

obo:VO_0005281 a rdfs:Class ;
  rdfs:label "2E151 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0002900 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium ompD/nmpC mutant vaccine" ;
  rdfs:comment "In a pig infection experiment including two oral immunizations with SalmoporcDeltaompD (OmpD, nmpC) and challenge with a multiresistant S. enterica serovar Typhimurium DT104 clinical isolate, we confirmed the protective efficacy of SalmoporcDeltaompD in pigs, showing a significant reduction of both clinical symptoms and colonization of lymph nodes and intestinal tract" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0006032 a rdfs:Class ;
  rdfs:label "meningococcal B unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0004784 a rdfs:Class ;
  rdfs:label "rVEE-HA(H1N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:OBI_0000712 a rdfs:Class ;
  rdfs:label "pathogen challenge" ;
  rdfs:comment "The administration of a live pathogenic organism to a host."@en ;
  rdfs:subClassOf obo:OBI_0003456 .

obo:VO_0005320 a rdfs:Class ;
  rdfs:label "202-CoV vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine manufactured by Shanghai Zerun Biotechnology, Walvax Biotechnology, and CEPI" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0007634 a rdfs:Class ;
  rdfs:label "mAb PC61 and DC/tumor fusion vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0011437 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum RplF protein vaccine" ;
  rdfs:subClassOf obo:VO_0012176 .

obo:IAO_8000015 a rdfs:Class ;
  rdfs:label "template generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated from a template specification and fillers for slots in that template."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/template> , <https://github.com/dosumis/dead_simple_owl_design_patterns/> , <https://doi.org/10.1186/s13326-017-0126-0> ;
  rdfs:subClassOf obo:IAO_8000014 .

obo:VO_0002187 a rdfs:Class ;
  rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.12)" .

obo:VO_0015676 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015562 , obo:VO_0015770 .

obo:VO_0000221 a rdfs:Class ;
  rdfs:label "pCMV-3FUB DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007483 a rdfs:Class ;
  rdfs:label "gp100 and GM-CSF DNA/Gold vaccine" ;
  rdfs:comment "A vaccine consisting of microscopic gold particles coated with plasmid DNA encoding the glycoprotein 100 (gp100) melanoma antigen and granulocyte-macrophage colony-stimulating factor (GM-CSF). Vaccination with gp100 and GM-CSF DNA/gold vaccine may stimulate the host immune system to direct cytotoxic T lymphocytes (CTL) against gp100 positive cells, resulting in decreased tumor growth. GM-CSF is thought to increase the induction and activation of antigen-presenting cells (APC), allowing for a reduction in the dose of gp100 administered." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0000329 a rdfs:Class ;
  rdfs:label "Mycoplasma hyopneumoniae vaccine" ;
  rdfs:comment "bacterial vaccine that protect against Mycoplasma hyopneumoniae infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000604 .

obo:VO_0001042 a rdfs:Class ;
  rdfs:label "BoHV-4 vaccine vector" ;
  rdfs:subClassOf obo:VO_0000283 .

obo:VO_0003231 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection [Heplisav-B]" ;
  rdfs:subClassOf obo:VO_0003270 .

obo:VO_0001975 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B9.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002360 .

obo:VO_0011236 a rdfs:Class ;
  rdfs:label "MSP4/5" ;
  rdfs:comment "Oral immunization of mice with Escherichia coli-expressed Plasmodium yoelii merozoite surface protein 4/5 or the C-terminal 19-kDa fragment of merozoite surface protein 1 induced systemic antibody responses and protected mice against lethal malaria infection [PubMed: 15385527]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015474 .

obo:VO_0020610 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension by Evans Vaccines" ;
  rdfs:subClassOf obo:VO_0020538 .

obo:VO_0018476 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0018455 .

obo:VO_0015890 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015620 , obo:VO_0015716 , obo:VO_0016008 .

obo:VO_0017803 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.016 MG/ML" ;
  rdfs:subClassOf obo:VO_0003196 .

obo:PR_000001159 a rdfs:Class ;
  rdfs:label "Toll-like receptor 8" ;
  rdfs:comment "A Toll-like receptor that is a translation product of the human TLR8 gene or a 1:1 ortholog thereof." ;
  rdfs:subClassOf obo:PR_000001096 .

obo:VO_0019876 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Flulaval 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019872 .

obo:VO_0015041 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0003303 .

obo:VO_0001745 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Modified Live Virus Vaccine (USDA: 14P1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000932 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0017325 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Suspension [Infanrix-Hib]" ;
  rdfs:subClassOf obo:VO_0017323 .

obo:VO_0018886 a rdfs:Class ;
  rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010305 , obo:VO_0010415 .

obo:VO_0005368 a rdfs:Class ;
  rdfs:label "Syntex Adjuvant Formulation" ;
  rdfs:comment "A muramyl dipeptide vaccine adjuvant that muramyl dipeptide derivative (threonyl-MDP) in an oil-in-water (o/w) emulsion vehicle." ;
  rdfs:subClassOf obo:VO_0000187 .

obo:VO_0007079 a rdfs:Class ;
  rdfs:label "Remestemcel-L Vaccine" ;
  rdfs:comment "Human mesenchymal stem cells (MSCs) harvested from bone marrow of healthy adult donors and expanded ex vivo, with potential immunosuppressive activity. Remestemcel-L cells are hypo-immunogenic due to lack of major histocompatibility II (MHC II) molecule expression, eliciting little, if any, host immune response upon intravenous infusion. Infusion of allogeneic MSCs may result in: a) increased production of anti-inflammatory cytokines, such as interleukin-10, prostaglandin E, and hepatocyte growth factor; b) decreased mononuclear phagocyte expression of indoleamine 2,3,-dioxygenase, which catabolizes L-tryptophan into its pro-inflammatory metabolites; and c) modulated dendritic cell (DC)maturation and disrupted activities of natural killer (NK) cells and CD8+ and CD4+ T cells. In addition, pluripotent MSCs, upon administration, may be recruited to damaged tissue sites, differentiating along specific lineages when stimulated." ;
  rdfs:subClassOf obo:VO_0005429 , obo:VO_0007657 .

obo:VO_0018471 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0018454 .

obo:VO_0007415 a rdfs:Class ;
  rdfs:label "monoclonal antibody A1G4 anti-idiotype vaccine" ;
  rdfs:comment "An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma, and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0005486 , obo:VO_0005495 , obo:VO_0007657 .

obo:VO_0001096 a rdfs:Class ;
  rdfs:label "Ovastim vaccine" ;
  rdfs:comment "A vaccine used to increase the fecundity in breeding ewes. Ovastim increases the number of multiple ovulations and therefore the number of multiple births." ;
  rdfs:subClassOf obo:VO_0000372 , obo:VO_0000455 , obo:VO_0000503 .

obo:VO_0011051 a rdfs:Class ;
  rdfs:label "Env/Rex/Tax" ;
  rdfs:comment "The bovine leukemia virus (BLV) envelope gene encoding extracellular glycoprotein gp51 (encoded by env gene) and transmembrane glycoprotein gp30 was cloned into a vehicle expression vector under the human cytomegalovirus (CMV) intermediate early promoter. The intramuscular injection of this plasmid vector generated a cellular immune response. Seven out of ten cows vaccinated with the DNA construct resisted a drastic challenge [PubMed: 10824867]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010797 .

obo:VO_0019280 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0003643 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003642 .

obo:VO_0004581 a rdfs:Class ;
  rdfs:label "IBV DNA vaccine pVAX1-N" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001502 .

obo:VO_0017003 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0016995 , obo:VO_0017489 .

obo:VO_0011563 a rdfs:Class ;
  rdfs:label "Neospora caninum NcMIC1 protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0001065 .

obo:VO_0011406 a rdfs:Class ;
  rdfs:label "Herpes simplex virus type 2 DNA vaccine encoding GB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0018156 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0018143 .

obo:VO_0002608 a rdfs:Class ;
  rdfs:label "metH from Neisseria meningitidis" ;
  rdfs:comment "A metH mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001417 .

obo:VO_0000636 a rdfs:Class ;
  rdfs:label "recombinant vector vaccine role" ;
  rdfs:comment "A vaccine role that indicates the vaccine being a recombinant vector vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0007537 a rdfs:Class ;
  rdfs:label "Folate-FITC vaccine" ;
  rdfs:comment "A conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity. Folate-FITC binds to folate receptors, which are overexpressed on the surfaces of many cancer cells including kidney and ovarian cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate, circulating anti-fluorescein antibodies may recognize and bind to the FITC moiety, resulting in antibody-dependent cellular cytotoxicity. " ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0001713 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.15)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0015846 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] by Waymade" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 .

obo:VO_0015535 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution [H B Vax]" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0001692 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 1 & 3, Live Herpesvirus Chimera Vaccine (USDA: 1631.R0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0011528 a rdfs:Class ;
  rdfs:label "infleunza virus DNA vaccine encoding NP from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0006099 a rdfs:Class ;
  rdfs:label "GLA-Alum vaccine adjuvant" ;
  rdfs:comment "A combination vaccine adjuvant of a synthetic TLR agonist and aluminum salt." ;
  rdfs:subClassOf obo:VO_0001354 .

obo:VO_0007696 a rdfs:Class ;
  rdfs:label "mRNA-based personalized cancer vaccine NCI-4650" ;
  rdfs:comment "A cancer vaccine targeting up to fifteen tumor-associated antigens (TAAs) that are specifically expressed by a patient's cancer cells, with potential immunostimulatory and antineoplastic activities. Up to fifteen neoantigen epitopes are incorporated in a proprietary formulation designed to maximize mRNA delivery and minimize mRNA-triggered immune responses. The mRNA-based PCV NCI-4650 is taken up and the mRNAs are translated by antigen presenting cells (APCs). Then, the expressed epitopes are presented via major histocompatibility complex (MHC) molecules on the surface of the APCs. This induces both cytotoxic T-lymphocyte (CTL)- and memory T-cell-dependent immune responses that specifically target and destroy the patient's cancer cells that express these neoantigens. Exome sequencing can identify certain gene mutations in a person's tumor. This can then be used to create cancer treatments. This mRNA vaccine might cause certain tumors to shrink. Immunogenic neoantigens and can predict for neoantigens binding the patient human leukocyte antigen (HLA) molecules from melanoma or epithelial cancer patients and use these epitopes for a personalized therapeutic messenger ribonucleic acid (mRNA) vaccine." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0007657 .

obo:VO_0020832 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0012185 .

obo:VO_0020884 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0020851 .

obo:VO_0018319 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabipur] Box of 5" ;
  rdfs:subClassOf obo:VO_0018290 , obo:VO_0018302 , obo:VO_0018324 .

obo:VO_0001303 a rdfs:Class ;
  rdfs:label "Murametide vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant made of murametide that has adjuvant activity similar to MDP." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0000124 a rdfs:Class ;
  rdfs:label "Zostavax vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000419 , obo:VO_0000455 .

obo:VO_0015519 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML [VACCIN GENHEVAC B]" ;
  rdfs:subClassOf obo:VO_0003230 .

obo:VO_0021030 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe [Zostavax] Box of 1" ;
  rdfs:subClassOf obo:VO_0021029 , obo:VO_0021031 .

obo:VO_0019865 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluarix Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020319 .

obo:VO_0018682 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML Oral Suspension [Rotarix]" ;
  rdfs:subClassOf obo:VO_0018680 , obo:VO_0018681 , obo:VO_0020188 .

obo:VO_0019875 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001176 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0000541 a rdfs:Class ;
  rdfs:label "equine EEV, VEE & WEV encephalomyelitis-tetanus toxoid" ;
  rdfs:subClassOf obo:VO_0001499 , obo:VO_0002420 .

obo:VO_0004147 a rdfs:Class ;
  rdfs:label "live, attenuated Rifampin-resistant rough mutants of Brucella melitensis vaccine" ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0018351 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003338 .

obo:NCBITaxon_9669 a rdfs:Class ;
  rdfs:label "Mustela putorius furo" ;
  rdfs:subClassOf obo:NCBITaxon_169418 .

obo:NCBITaxon_171 a rdfs:Class ;
  rdfs:label "Leptospira" ;
  rdfs:subClassOf obo:NCBITaxon_203692 .

obo:VO_0017974 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0017944 , obo:VO_0017961 .

obo:VO_0003047 a rdfs:Class ;
  rdfs:label "Schistosoma vaccine" ;
  rdfs:comment "A protozoan vaccine against Schistosoma infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000417 .

obo:VO_0003896 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML [Flublok 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003894 .

obo:VO_0019994 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0003307 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 52 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003299 , obo:VO_0010446 .

obo:VO_0018431 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumopur]" ;
  rdfs:subClassOf obo:VO_0018421 .

obo:VO_0002651 a rdfs:Class ;
  rdfs:label "nuoG from Salmonella Gallinarum" ;
  rdfs:comment "A nuoG mutant is attenuated in chickens and induced significant protection from challenge with wild type S. Gallinarum" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001420 .

obo:VO_0015308 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 1" ;
  rdfs:subClassOf obo:VO_0015307 , obo:VO_0015310 .

obo:VO_0004133 a rdfs:Class ;
  rdfs:label "P1-HspB (fusion of protein 1 and heat-shock protein B) vaccine" ;
  rdfs:subClassOf obo:VO_0000463 .

obo:VO_0018401 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 14 vaccine 0.001 MG" ;
  rdfs:subClassOf obo:VO_0003219 .

obo:VO_0002905 a rdfs:Class ;
  rdfs:label "Salmonella Gallinarum relA/spoT mutant vaccine" ;
  rdfs:comment "A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum" ;
  rdfs:subClassOf obo:VO_0002508 .

obo:VO_0004039 a rdfs:Class ;
  rdfs:label "Psuedorabies DNA vaccine encoding IE180 protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000750 .

obo:VO_0012408 a rdfs:Class ;
  rdfs:label "DnaK from Mycobacterium tuberculosis" ;
  rdfs:comment "In an ex vivo transfection approach with a retroviral vector a single antigen (hsp70) could evoke strong protection in mice [PubMed: 9234527]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0020144 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine Injection [Menactra]" ;
  rdfs:subClassOf obo:VO_0000071 , obo:VO_0000561 , obo:VO_0010445 .

obo:VO_0000433 a rdfs:Class ;
  rdfs:label "vaccinia virus vaccine" ;
  rdfs:comment "Smallpox virus vaccine that uses vaccinia virus. The vaccine is made from a laboratory strain of the live vaccinia virus that has been attenuated, or weakened, so that it stimulates an immune response without causing the severe disease associated with smallpox." ;
  rdfs:subClassOf obo:VO_0000651 .

obo:NCBITaxon_287 a rdfs:Class ;
  rdfs:label "Pseudomonas aeruginosa" ;
  rdfs:subClassOf obo:NCBITaxon_286 .

obo:BFO_0000018 a rdfs:Class ;
  rdfs:label "zero-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:VO_0007604 a rdfs:Class ;
  rdfs:label "Flagrp170 vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0003856 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML" ;
  rdfs:subClassOf obo:VO_0003849 .

obo:VO_0012374 a rdfs:Class ;
  rdfs:label "PPE14" ;
  rdfs:comment "immunization with the soluble recombinant rMTB41 protein plus adjuvant, a regimen known to generate primarily CD4+ T cells, resulted in induction of protection comparable to BCG in two well-established animal models of tuberculosis (mice and guinea pigs) [PubMed: 15917115]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0001669 a rdfs:Class ;
  rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.5C)" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:VO_0006069 a rdfs:Class ;
  rdfs:label "SARS-COV-2 COVID-19 mRNA bivalent original/Omicron BA.1 Non-US Vaccine Product (Comirnaty Bivalent) Pfizer-BioNTech" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0000247 a rdfs:Class ;
  rdfs:label "vaccine efficacy" ;
  rdfs:comment """Vaccine efficacy is an efficacy of a vaccine in induction of protective immune response in vivo or protection against infection of a virulent pathogen. 
Specifically, vaccine efficacy (VE) is the percentage reduction in disease incidence attributable to vaccination, calculated by means of the following equation:
VE(%) = (U - V)/U x 100
where U = the incidence in unvaccinated people and 
V = the incidence in vaccinated people.
Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Editors: Plotkin S, et al. 2008. p1542-71.""" ;
  rdfs:subClassOf obo:PATO_0001029 .

obo:VO_0002143 a rdfs:Class ;
  rdfs:label "Marek's Disease-Newcastle Disease Serotype 3, Live Marek's Disease Vector Vaccine (USDA: 16N1.R0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002447 , obo:VO_0007748 .

obo:VO_0019980 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Injectable Suspension [Flulaval 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019978 , obo:VO_0020338 .

obo:VO_0010879 a rdfs:Class ;
  rdfs:label "GatA" ;
  rdfs:comment """Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #3, gatA) was found to be protective.  Three of the clones (CP #1) elicited protection that was statistically higher than the unvaccinated control, which has high variance [PubMed: 15811648].

Note:  Part of CP #3 also belongs to gatB""" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:VO_0016054 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 25" ;
  rdfs:subClassOf obo:VO_0003259 .

obo:VO_0016762 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003429 .

obo:NCBITaxon_11021 a rdfs:Class ;
  rdfs:label "Eastern equine encephalitis virus" ;
  rdfs:subClassOf obo:NCBITaxon_11019 .

obo:VO_0001266 a rdfs:Class ;
  rdfs:label "VSA-3 vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant which is an emulsion plus DDA." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:OPL_0000394 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi merozoite" ;
  rdfs:comment "A Plasmodium knowlesi in merozoite stage." ;
  rdfs:subClassOf obo:NCBITaxon_5850 , obo:OPL_0000270 .

obo:VO_0002239 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47A5.20)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001471 , obo:VO_0002392 , obo:VO_0007748 .

obo:VO_0016741 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Diphtherie-Adsorbat-Impfstoff Behring] Box of 10" ;
  rdfs:subClassOf obo:VO_0016709 , obo:VO_0016768 .

obo:VO_0001994 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:VO_0011400 a rdfs:Class ;
  rdfs:label "Puumala virus PUUVsSgp1 (NP) protein vaccine" ;
  rdfs:subClassOf obo:VO_0012167 .

obo:VO_0017778 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017777 .

obo:VO_0000493 a rdfs:Class ;
  rdfs:label "natural active immunization" ;
  rdfs:comment "natural active immunization is an active immunization that occur naturally when a person or animal comes in contact with antigens includeing microbes." ;
  rdfs:subClassOf obo:VO_0000491 .

obo:VO_0019583 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluzone Quadrivalent 2023 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020496 .

obo:VO_0003263 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0010711 .

obo:VO_0020949 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML [Flumist]" ;
  rdfs:subClassOf obo:VO_0000044 , obo:VO_0000578 , obo:VO_0004914 .

obo:VO_0002039 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis-Chicken Anemia Virus-Fowl Pox C155Live and Modified Live C212Virus Vaccine (USDA: 10T1.40)+C433" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002325 , obo:VO_0007748 .

obo:VO_0016195 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:VO_0007403 a rdfs:Class ;
  rdfs:label "hTERT multipeptide/montanide ISA-51 VG/Imiquimod vaccine GX 301" ;
  rdfs:comment "A therapeutic cancer vaccine consisting of four epitopes derived from the human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, including hTERT (540-548) acetate, hTERT (611-626) acetate, hTERT (672-686) acetate and hTERT (766-780) acetate, emulsified individually in the adjuvant montanide ISA-51 VG and administered with the immune response modifier (IRM) imiquimod, with potential immunostimulating and antineoplastic activities. Each hTERT peptide emulsion is administered individually by intradermal injection. Subsequently, imiquimod is applied topically to the injection site(s). Vaccination with GX 301 may elicit a cytotoxic T-cell (CTL) response against telomerase-expressing tumor cells. Telomerase is expressed in the majority of human cancer cells, infrequently expressed in normal cells, and is directly linked to tumorigenesis. Imiquimod stimulates cytokine production through the activation of toll-like receptor 7 (TLR-7), and also exhibits antiproliferative effects. Montanide ISA-51, also known as incomplete Freund's adjuvant (IFA), is a stabilized water-in-oil emulsion containing mineral oil with mannide oleate, which contains vegetable-grade (VG) oleic acid derived from olive oil. ISA-51 non-specifically stimulates cell-mediated immune responses to antigens." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0011517 a rdfs:Class ;
  rdfs:label "Theileria annulata Subunit SPAG-1 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000909 .

obo:VO_0016837 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016759 .

obo:VO_0002987 a rdfs:Class ;
  rdfs:label "obsolete Pseudorabies virus gp50/gp63 mutant vaccine" ;
  rdfs:comment "A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky's disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3" .

obo:VO_0000625 a rdfs:Class ;
  rdfs:label "conjugate vaccine role" ;
  rdfs:comment "A vaccine role that indicates the vaccine being a conjugate vaccine. " ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0017738 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML [Covaxis]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0017802 .

obo:VO_0018001 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0018000 .

obo:VO_0015159 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Mevita" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0001137 a rdfs:Class ;
  rdfs:label "Eimeria tenella vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000906 .

obo:VO_0021100 a rdfs:Class ;
  rdfs:label "influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0020305 .

obo:VO_0017767 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated Injectable Solution [Acel P Lederle]" ;
  rdfs:subClassOf obo:VO_0017806 .

obo:VO_0000419 a rdfs:Class ;
  rdfs:label "Varicella-zoster virus live vaccine" ;
  rdfs:comment "a Varicella-zoster virus vaccine that is live attenuated." ;
  rdfs:subClassOf obo:VO_0000669 , obo:VO_0001220 .

obo:NCBITaxon_620 a rdfs:Class ;
  rdfs:label "Shigella" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:VO_0001542 a rdfs:Class ;
  rdfs:label "Feline immunodeficiency virus Killed Virus Vaccine (USDA: 15A5.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001508 , obo:VO_0007748 .

obo:VO_0003104 a rdfs:Class ;
  rdfs:label "Rabiesvax vaccine" ;
  rdfs:subClassOf obo:VO_0000650 , obo:VO_0000712 .

obo:VO_0016168 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0016003 .

obo:VO_0005325 a rdfs:Class ;
  rdfs:label "VSA-2 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is synthesized by derivatizing a natural Momordica saponin in one step.  VSA-2 is chemically stable. VSA-2 is much less toxic than QS-21.  VSA-2 is more Th1-biased than QS-21. Momordica saponins are isolated from widely available and sustainable sources." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0016955 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0016954 , obo:VO_0017412 .

obo:VO_0017431 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine Injectable Solution [PedvaxHIB]" ;
  rdfs:subClassOf obo:VO_0017430 , obo:VO_0017433 .

obo:DOID_3717 a rdfs:Class ;
  rdfs:label "gastric adenocarcinoma"@en ;
  rdfs:comment "A stomach carcinoma that derives_from epithelial cells of glandular origin."@en ;
  rdfs:subClassOf obo:DOID_299 , obo:DOID_5517 .

obo:VO_0019475 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.015 MG/ML / Neisseria meningitidis 0.25 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0019469 .

obo:VO_0018101 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Prefilled Syringe [Priorix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018100 .

obo:VO_0018470 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0018454 .

obo:VO_0016684 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Infanrix]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0018193 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0015589 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015528 , obo:VO_0015599 .

obo:VO_0015575 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat]" ;
  rdfs:subClassOf obo:VO_0015492 , obo:VO_0015537 .

obo:CHEBI_7507 a rdfs:Class ;
  rdfs:label "neomycin" ;
  rdfs:comment "A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0018708 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 UNT Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018707 , obo:VO_0018807 .

obo:VO_0007707 a rdfs:Class ;
  rdfs:label "NEO-PV-01 vaccine" ;
  rdfs:comment "A cancer vaccine consisting of patient-specific mutated peptide epitopes, which are immunogenic and unique to the patient's tumor, with potential immunomodulating and antineoplastic activities. The neoantigen-based anti-cancer vaccine NEO-PV-01 stimulates the host immune system to mount a specific and potent cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the neoantigens, which results in tumor cell lysis. Both metastatic squamous non-small cell lung cancer (NSCLC) and extensive stage small cell lung cancer (SCLC) are incurable with current therapies, but due to mutations induced by cigarette smoke, typically express a large number of altered proteins that can be recognized as foreign by the immune system. Targeting the immune system against tumor specific antigens using a peptide vaccine could lead to improved response rate and prolonged overall survival with no additional toxicity when combined with Pembrolizumab (monoclonal antibodies that block PD-1/PD-L1 interactions) and standard of care chemotherapy." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0005379 a rdfs:Class ;
  rdfs:label "PIKA vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0010831 a rdfs:Class ;
  rdfs:label "Babesia canis protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0002212 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002412 , obo:VO_0007748 .

obo:VO_0016309 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015926 .

obo:VO_0005331 a rdfs:Class ;
  rdfs:label "recombinant viral vector vaccine" ;
  rdfs:comment "A recombiant vector vaccine that is has a viral vector." ;
  rdfs:subClassOf obo:VO_0000484 .

obo:VO_0004713 a rdfs:Class ;
  rdfs:label "rMeV- SCD vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0017855 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide 0.008 MG/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010290 , obo:VO_0010444 .

obo:VO_0020133 a rdfs:Class ;
  rdfs:label "mumps virus vaccine live, Jeryl Lynn strain / rubella virus vaccine live (Wistar RA 27-3 strain) Injectable Solution [Biavax II]" ;
  rdfs:subClassOf obo:VO_0020132 .

obo:VO_0002659 a rdfs:Class ;
  rdfs:label "ruvB from Salmonella Typhimurium" ;
  rdfs:comment "A ruvB mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0019698 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:NCBITaxon_186778 a rdfs:Class ;
  rdfs:label "Novirhabdovirus" ;
  rdfs:subClassOf obo:NCBITaxon_11270 .

obo:VO_0018006 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) Injection [Boostrix]" ;
  rdfs:subClassOf obo:VO_0018004 .

obo:IDO_0000403 a rdfs:Class ;
  rdfs:label "parasite role"@en ;
  rdfs:comment "A symbiont role borne by an organism in virtue of the fact that it derives a growth, survival, or fitness advantage from symbiosis while the other symbiont's growth, survival, or fitness is reduced."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0010291 a rdfs:Class ;
  rdfs:label "Bacillus anthracis strain V770-NP1-R antigen vaccine" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0020159 a rdfs:Class ;
  rdfs:label "Brucella abortus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0001193 a rdfs:Class ;
  rdfs:label "vaccination mouse strain datum" ;
  rdfs:comment """A measurement datum that represents a specific mouse strain used for vaccination. Different strains can be represented using discretized digitals.  For example, 0 = BALB/c; 1 = CD1; 2 = mixed/outbred; 3 = C57BL/6; 4 = OF1; 5 = 129/Sv; 6 = Swiss albino.
""" ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0001857 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0002436 , obo:VO_0007748 .

obo:VO_0002969 a rdfs:Class ;
  rdfs:label "Hepatitis B virus X protein mutant vaccine" ;
  rdfs:comment "Researchers generated a series of woodchuck hepatitis virus (WHV) X mutants. Woodchucks inoculated with X mutants, including those with no serologic evidence of infection, were protected from later challenge with infectious Woodchuck Hepatitis Virus, suggesting previous infection with resulting protective immunity" ;
  rdfs:subClassOf obo:VO_0000644 .

obo:VO_0019377 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection [Vaxelis]" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0020832 .

obo:VO_0000966 a rdfs:Class ;
  rdfs:label "recombinant vaccine vector E. coli vaccine" ;
  rdfs:comment "An E. coli vaccine that uses a recombinant vaccine vector to express an E. coli antigen(s)" ;
  rdfs:subClassOf obo:VO_0000041 , obo:VO_0000484 .

obo:DOID_1273 a rdfs:Class ;
  rdfs:label "respiratory syncytial virus infectious disease"@en ;
  rdfs:comment "A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus, which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress."@en ;
  rdfs:subClassOf obo:DOID_934 .

obo:VO_0001075 a rdfs:Class ;
  rdfs:label "Salmonella typhi vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector that uses a Salmonella typhi strain" ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0020352 a rdfs:Class ;
  rdfs:label "Flumist Quadrivalent 2020-2021 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000982 , obo:VO_0010424 .

obo:VO_0019931 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Prefilled Syringe [Fluzone Intradermal 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0010418 , obo:VO_0019923 .

obo:VO_0010824 a rdfs:Class ;
  rdfs:label "Theileria parva protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0007426 a rdfs:Class ;
  rdfs:label "multipeptide vaccine S-588210" ;
  rdfs:comment "A cancer vaccine composed of a combination of the injectable formulations S-488210, which contains the three HLA-A*02:01-restricted peptides up-regulated lung cancer 10 (lymphocyte antigen 6K; LY6K; URLC10), cell division cycle-associated protein 1 (kinetochore protein Nuf2; NUF2; CDCA1) and insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3; KOC1) and S-488211, which contains the two HLA-A*02:01-restricted peptides DEP domain-containing protein 1A (DEPDC1) and M-phase phosphoprotein 1 (kinesin-like protein KIF20B; MPHOSPH1), with potential immunostimulatory and antitumor activities. Upon administration, multipeptide vaccine S-588210 may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing KOC1, CDCA1, URLC10, DEPDC1 or MPHOSPH1 peptides, resulting in tumor cell lysis and decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0015214 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015206 , obo:VO_0015304 .

obo:VO_0020014 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 50000000 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003500 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0007526 a rdfs:Class ;
  rdfs:label "ESR1 peptide vaccine" ;
  rdfs:comment "A cancer vaccine comprised of estrogen receptor alpha (ERa; estrogen receptor 1; ESR1) mutant peptides, combined with the immunoadjuvants granulocyte-macrophage colony-stimulating factor (GM-CSF) and montanide ISA, with potential immunomodulating and antineoplastic activities. ESR1 mutant peptides in the ESR1 peptides/GM-CSF/montanide ISA vaccine may activate the immune system to induce an immune response against tumor cells expressing these ESR1 mutations.  Cancer peptides used in this vaccine are derived from the estrogen receptor and are combined with the adjuvant Montanide ISA and GM-CSF to enhance their immune response. The vaccine may improve outcomes of patients with endocrine resistant breast cancer. " ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0007657 .

obo:NCBITaxon_39944 a rdfs:Class ;
  rdfs:label "Caprine alphaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_10319 .

obo:OGG_3000888772 a rdfs:Class ;
  rdfs:label "phoP" ;
  rdfs:comment "Possible two component system response transcriptional positive regulator PhoP" ;
  rdfs:subClassOf obo:OGG_2060083332 .

obo:VO_0016323 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015935 .

obo:VO_0017336 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution [Pediacel]" ;
  rdfs:subClassOf obo:VO_0017335 .

obo:VO_0005078 a rdfs:Class ;
  rdfs:label "pVF DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pVF." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019650 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010420 .

obo:VO_0004617 a rdfs:Class ;
  rdfs:label "short overlapping peptides and full-length recombinant protein vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0015209 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0015208 .

obo:VO_0015918 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015631 , obo:VO_0015683 , obo:VO_0016026 .

obo:VO_0020896 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Influsplit]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0019177 a rdfs:Class ;
  rdfs:label "0.5 ML hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019508 .

obo:VO_0019676 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003779 , obo:VO_0010427 , obo:VO_0019675 .

obo:VO_0020371 a rdfs:Class ;
  rdfs:label "Typhoid Vaccine Live Ty21a Extended Release Oral Capsule" ;
  rdfs:subClassOf obo:VO_0003449 .

obo:VO_0017877 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:NCBITaxon_1307 a rdfs:Class ;
  rdfs:label "Streptococcus suis" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:VO_0003546 a rdfs:Class ;
  rdfs:label "Flaviviridae vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Flaviviridae." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0016637 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Emra-Med" ;
  rdfs:subClassOf obo:VO_0016621 .

obo:VO_0004018 a rdfs:Class ;
  rdfs:label "influenza virus HA protein vaccine (influenza A virus (A/Fukuoka/C29/85(H3N2)))" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0010442 a rdfs:Class ;
  rdfs:label "licensed human mumps virus vaccine" ;
  rdfs:comment "Mumps virus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000656 .

obo:VO_0012373 a rdfs:Class ;
  rdfs:label "HBHA" ;
  rdfs:comment "Purified preparations of HBHA were emulsified in a dimethyldioctadecylammonium bromide-monophosphoryl lipid A adjuvant and tested for the ability to reduce M. tuberculosis infection in the mouse aerosol challenge model for tuberculosis. The HBHA-containing vaccine gave a approximately 0.7-log reduction in CFU in both mouse lungs and spleens compared to adjuvant controls 28 days following challenge [PubMed: 15557600]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0017645 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [Tet Aktiv]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0011154 a rdfs:Class ;
  rdfs:label "F1-ATPase" ;
  rdfs:comment "Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani.  Results demonstrated that liposomal LD31 (ATP synthase alpha chain) reduced parasite burden by 74%-77% [PubMed: 19503834]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0012356 a rdfs:Class ;
  rdfs:label "Streptococcus agalactiae protein" ;
  rdfs:subClassOf obo:VO_0010752 .

obo:NCBITaxon_160 a rdfs:Class ;
  rdfs:label "Treponema pallidum" ;
  rdfs:subClassOf obo:NCBITaxon_136 .

obo:VO_0010489 a rdfs:Class ;
  rdfs:label "licensed human malaria vaccine" ;
  rdfs:comment "malaria vaccine is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000761 .

obo:VO_0010915 a rdfs:Class ;
  rdfs:label "Pal" ;
  rdfs:comment "Recombinant P6 (pal) was capable of eliciting a protective antibody response against live H. influenzae type b challenge in a modified infant rat model of bacteremia [PubMed: 9261944]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:NCBITaxon_11901 a rdfs:Class ;
  rdfs:label "Bovine leukemia virus" ;
  rdfs:subClassOf obo:NCBITaxon_327045 .

obo:VO_0007712 a rdfs:Class ;
  rdfs:label "NY-ESO-1, MAGE-A1, and MAGE-A3 dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine that is made from the subject's blood cells and is designed to interact in the patient's body with cells that are programmed to fight specific tumor proteins NY-ESO-1, Melanoma Antigen Gene-A1 (MAGE-A1) and Melanoma Antigen Gene-A3 (MAGE-A3). The vaccine can be given in combination with decitabine which may increase the amount and activity of these cancer proteins on the surface of tumor cells to increase the possibility that the vaccine will stimulate cells to act against the tumor cells. The dendritic cells may stimulate CD4 and CD8 antigen specific T cells in patients with relapsed or refractory pediatric high grade gliomas, medulloblastomas, and central nervous system primitive neuroectodermal tumors (CNS PNETs)." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:OBI_0000750 a rdfs:Class ;
  rdfs:label "study design independent variable"@en ;
  rdfs:comment "a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled"@en ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0007562 a rdfs:Class ;
  rdfs:label "mRNA-Derived Prostate Cancer Vaccine CV9103" ;
  rdfs:comment "A prostate cancer vaccine containing mRNAs encoding prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), prostate stem cell antigen (PSCA) and six-transmembrane epithelial antigen of the prostate (STEAP), with potential antitumor activity. Upon administration, mRNA-derived prostate cancer vaccine CV9103 may stimulate the immune system to mount a cytotoxic T lymphocyte response (CTL) against PSA-, PSMA-, PSCA- and STEAP-expressing prostate tumor cells. The mRNA used in this vaccine is modified and formulated to have enhanced translational potency and adjuvant activities. PSA, PSMA, PSCA and STEAP may be upregulated in prostate cancer cells; their expression in prostate cancer has been correlated with disease progression." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0017598 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017597 , obo:VO_0017603 .

obo:VO_0004350 a rdfs:Class ;
  rdfs:label "HIV recombinant vector vaccine MVA.HIVA encoding env and rev" ;
  rdfs:subClassOf obo:VO_0000295 , obo:VO_0000484 .

obo:VO_0002256 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4845.32)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002429 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0011035 a rdfs:Class ;
  rdfs:label "Cpn60" ;
  rdfs:comment "A soluble fraction obtained from Bordetella pertussis was evaluated as adjuvant for the pertussis component of the Diphtheria-Pertussis-Tetanus (DPT) vaccine. High levels of antibodies were induced, and a 78% protection rate of mice challenged with live B. pertussis was observed. Two proteins were identified as the 73 kDa N-terminal alpha-domain of BrkA autotransporter protein and the Cpn60/60 kDa chaperonin. Both stimulated antibodies against pertussis and induced a 42% protection rate against the challenge [PubMed: 17011680]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010847 .

obo:NCBITaxon_40269 a rdfs:Class ;
  rdfs:label "Aliivibrio salmonicida" ;
  rdfs:subClassOf obo:NCBITaxon_641 .

obo:VO_0011394 a rdfs:Class ;
  rdfs:label "Marburg Virus Nucleoprotein Vaccine" ;
  rdfs:subClassOf obo:VO_0012163 .

obo:OPL_0000348 a rdfs:Class ;
  rdfs:label "Plasmodium vivax sporozoite stage" ;
  rdfs:comment "A sporozoite stage in Plasmodium vivax life cycle." ;
  rdfs:subClassOf obo:OPL_0000152 , obo:OPL_0000300 , obo:OPL_0000374 .

obo:VO_0007681 a rdfs:Class ;
  rdfs:label "intracel KLH vaccine" ;
  rdfs:comment "A cancer vaccine that could teach T-cells to detect and kill cancer cells better. Intracel KLH is given without adjuvant subcutaneously and with Tetanus Toxoid 0.5 ml intramuscularly." ;
  rdfs:subClassOf obo:VO_0000177 , obo:VO_0000577 .

obo:VO_0003607 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2013-2014 Formula Injectable Product" ;
  rdfs:subClassOf obo:VO_0003579 .

obo:VO_0016941 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxin 10 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017403 .

obo:VO_0016843 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 10 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016815 .

obo:VO_0015224 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta] Box of 10" ;
  rdfs:subClassOf obo:VO_0015217 , obo:VO_0015228 , obo:VO_0015309 .

obo:VO_0000891 a rdfs:Class ;
  rdfs:label "phenoxy ethanol vaccine preservative" ;
  rdfs:subClassOf obo:VO_0000851 .

obo:VO_0005311 a rdfs:Class ;
  rdfs:label "Th1/Th2 mixed immune profile" ;
  rdfs:comment "An immune profile that is characterized by the presense of both Type 1 and Type 2 T helper  (Th1 and Th2) cells." ;
  rdfs:subClassOf obo:VO_0005308 .

obo:VO_0006079 a rdfs:Class ;
  rdfs:label "Tick-borne encephalitis vaccine inactivated preservative free 0.25mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000635 , obo:VO_0000712 , obo:VO_0000952 .

obo:VO_0018017 a rdfs:Class ;
  rdfs:label "poliomyelitis virus type 1 brunhilde 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution [Poliovaccine Ssi]" ;
  rdfs:subClassOf obo:VO_0018013 .

obo:VO_0020079 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.12 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.12 MG/ML Prefilled Syringe [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0002692 a rdfs:Class ;
  rdfs:label "nlpD from Yersinia pestis" ;
  rdfs:comment "An nlpD mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001426 .

obo:VO_0010120 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii SAG5B" ;
  rdfs:comment "A SAG5B protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0015307 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015299 , obo:VO_0015306 .

obo:VO_0007649 a rdfs:Class ;
  rdfs:label "procarbazine, dactinomycin, velba vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0018070 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Priorix-Tetra] Box of 20" ;
  rdfs:subClassOf obo:VO_0018065 , obo:VO_0018077 , obo:VO_0018153 .

obo:VO_0007163 a rdfs:Class ;
  rdfs:label "Recombinant Vaccinia PSA Vaccine" ;
  rdfs:comment "A vaccine consisting of recombinant vaccinia virus encoding prostate specific antigen (PSA). Vaccination with recombinant vaccinia prostate-specific antigen vaccine stimulates the host immune system to mount a cytotoxic T-cell response against tumor cells expressing PSA." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0018113 a rdfs:Class ;
  rdfs:label "1 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution [Priorix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018110 .

obo:VO_0002730 a rdfs:Class ;
  rdfs:label "M2 from Influenza virus" ;
  rdfs:comment "Mutant influenza virus that lacks the transmembrane and cytoplasmic tail domains of M2 (M2 knockout [M2KO]) from Influenza A virus (A/Puerto Rico/8/34(H1N1)) is attenuated in both cell culture and mice. Mice intranasally vaccinated with M2KO virus developed protective immune responses and survived a lethal challenge with the wild-type virus, suggesting that the M2KO virus has potential as a live attenuated vaccine" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000185 .

obo:VO_0005235 a rdfs:Class ;
  rdfs:label "NDV-HXP-S vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine by Mahidol University" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005199 .

obo:VO_0003402 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003400 .

obo:VO_0016785 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Revaxis] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016726 .

obo:VO_0004991 a rdfs:Class ;
  rdfs:label "COVAXIN vaccine" ;
  rdfs:comment "BBV152 (also known as Covaxin) is an inactivated COVID-19 vaccine that is developed by Bharat Biotech in collaboration with the Indian Council of Medical Research." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0018092 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution Box of 20" ;
  rdfs:subClassOf obo:VO_0018084 , obo:VO_0018171 .

obo:VO_0000172 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum gene" ;
  rdfs:subClassOf obo:VO_0000171 .

obo:VO_0020116 a rdfs:Class ;
  rdfs:label "measles virus vaccine live, Enders' attenuated Edmonston strain 2000 UNT/ML / mumps virus vaccine live, Jeryl Lynn strain 25000 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 2000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0020114 .

obo:VO_0007456 a rdfs:Class ;
  rdfs:label "Human Prostate-Specific Membrane Antigen Plasmid DNA Vaccine" ;
  rdfs:comment "A vaccine consisting of a plasmid DNA encoding the human prostate-specific membrane antigen (PSMA). Upon administration, expressed PSMA may stimulate a cytotoxic T cell response against tumor cells that express this antigen, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0005494 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0020153 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen 0.12 MG/ML / Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0010205 .

obo:VO_0020494 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2022 Southern Hemisphere vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010430 .

obo:VO_0003332 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 9N vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003254 .

obo:VO_0018794 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0020707 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution Box of 3" ;
  rdfs:subClassOf obo:VO_0020702 .

obo:VO_0001085 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus vaccine" ;
  rdfs:comment "Chlamydia bacterial vaccine against C. abortus infection" ;
  rdfs:subClassOf obo:VO_0000573 .

obo:VO_0010236 a rdfs:Class ;
  rdfs:label "intevention interval variable" ;
  rdfs:comment "A variable representing the interval between the vaccination and pathogen challenge start" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0004092 a rdfs:Class ;
  rdfs:label "MVA vaccine" ;
  rdfs:subClassOf obo:VO_0000651 .

obo:VO_0011448 a rdfs:Class ;
  rdfs:label "Eimeria tenella vaccine rBCG pMV361-Rho" ;
  rdfs:subClassOf obo:VO_0001137 .

obo:VO_0001297 a rdfs:Class ;
  rdfs:label "interleukin-1b vaccine adjuvant" ;
  rdfs:comment "A cytokine vaccine adjuvant that includes IL-1b." ;
  rdfs:subClassOf obo:VO_0001353 .

obo:VO_0010046 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum MSP4" ;
  rdfs:comment "A MSP4 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0018702 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1000 TCID Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018700 , obo:VO_0018711 .

obo:VO_0010089 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii CyP" ;
  rdfs:comment "A CyP protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0003419 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003415 .

obo:VO_0017685 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017741 .

obo:VO_0017578 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0017555 .

obo:VO_0017008 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution [Tetanol] Box of 10 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0017007 .

obo:VO_0019192 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010420 .

obo:VO_0005019 a rdfs:Class ;
  rdfs:label "pPA63-LAMP1 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pPA63-LAMP1." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0017935 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML Prefilled Syringe [ActHIB]" ;
  rdfs:subClassOf obo:VO_0017901 .

obo:VO_0003596 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML [Fluzone 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003594 .

obo:VO_0020051 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Fluzone 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020478 .

obo:VO_0015782 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0015595 .

obo:VO_0015611 a rdfs:Class ;
  rdfs:label "1 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015558 , obo:VO_0015590 , obo:VO_0015658 .

obo:NCBITaxon_91561 a rdfs:Class ;
  rdfs:label "Artiodactyla" ;
  rdfs:subClassOf obo:NCBITaxon_314145 .

obo:VO_0003213 a rdfs:Class ;
  rdfs:label "Diphtheria Toxoid-Pertussis-Poliovirus vaccine" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000664 , obo:VO_0000735 , obo:VO_0000765 .

obo:VO_0007382 a rdfs:Class ;
  rdfs:label "HPV-6-targeting immunotherapeutic vaccine INO-3106" ;
  rdfs:comment "A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus subtype 6 (HPV-6), with potential immunostimulating and antineoplastic activities. Administered via intramuscular electroporation, HPV-6-targeting immunotherapeutic vaccine INO-3106 expresses the HPV-6 E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells that are expressing those proteins, resulting in tumor cell lysis. HPV-6 infections are associated with aerodigestive malignancies." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0018178 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0018175 .

obo:VO_0007510 a rdfs:Class ;
  rdfs:label "CDX-1307 vaccine" ;
  rdfs:comment "A cancer vaccine for bladder cancer designed to generate an immune response against a protein called human chorionic gonadotropin-beta (hCG-β). hCG-β is made by several types of cancers, including bladder cancer, and has been shown to be associated with shorter times to development of metastases and reduced survival in bladder cancer. Administering the CDX-1307 vaccine will cause the body's immune system to attack bladder cancer cells in order to kill them or otherwise keep them from spreading or coming back. The human monoclonal antibody (B11) directed against the mannose receptor and linked to the beta-subunit of human chorionic gonadotropin (hCG beta) with potential immunostimulating and antineoplastic activities. The monoclonal antibody moiety of human monoclonal antibody B11-hCG beta fusion protein CDX-1307 binds to mannose receptors on antigen presenting cells (APCs), including human dendritic cells (DCs) and macrophages. APCs present the processed hCG beta antigen on their cell surfaces, which may initiate an antibody-dependent cell-mediated cytotoxicity (ADCC) response against hCG beta-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0020272 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 5 LFU" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0001460 a rdfs:Class ;
  rdfs:label "Orf Virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Orf Virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000512 .

obo:NCBITaxon_28344 a rdfs:Class ;
  rdfs:label "Porcine reproductive and respiratory syndrome virus" ;
  rdfs:subClassOf obo:NCBITaxon_76803 .

obo:VO_0016443 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0004100 a rdfs:Class ;
  rdfs:label "inactivated Campylobacter jejuni whole-cell vaccine" ;
  rdfs:subClassOf obo:VO_0001214 , obo:VO_0012182 .

obo:VO_0019243 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hawaii/70/2019 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Minnesota/41/2019 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020325 .

obo:VO_0016391 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat] Box of 3 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015954 .

obo:VO_0004795 a rdfs:Class ;
  rdfs:label "Toxminus-PLD toxoid vaccine" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0002789 .

obo:VO_0015182 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015181 .

obo:VO_0004271 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii TyCS-VLP vaccine" ;
  rdfs:subClassOf obo:VO_0002514 .

obo:VO_0020025 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injectable Suspension [Fluvirin 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020019 , obo:VO_0020471 .

obo:VO_0000963 a rdfs:Class ;
  rdfs:label "E. coli toxoid vaccine" ;
  rdfs:comment "an E. coli vaccine that uses toxoid antigen" ;
  rdfs:subClassOf obo:VO_0000041 , obo:VO_0000561 .

obo:VO_0004028 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi OspA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000764 .

obo:VO_0019823 a rdfs:Class ;
  rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010433 .

obo:VO_0016177 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0017605 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0017683 .

obo:VO_0018714 a rdfs:Class ;
  rdfs:label "Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injection [Ervevax]" ;
  rdfs:subClassOf obo:VO_0018713 .

obo:VO_0002892 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium hfq mutant vaccine" ;
  rdfs:comment "Oral immunization with the Salmonella hfq deletion mutant efficiently protects mice against subsequent oral challenge with virulent strain of Salmonella Typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0018130 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Solution [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0000069 , obo:VO_0018129 .

obo:VO_0017637 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0017631 .

obo:VO_0002722 a rdfs:Class ;
  rdfs:label "iCP0 from Herpes simplex virus type 1 and 2" ;
  rdfs:comment "A live-attenuated HSV-2 ICP0 virus provides significant protection against wild-type HSV-2 (MS strain) challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001454 .

obo:VO_0004249 a rdfs:Class ;
  rdfs:label "Mutagrip vaccine with P40 adjuvant" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0010337 a rdfs:Class ;
  rdfs:label "AFLURIA SOUTHERN HEMISPHERE vaccine" ;
  rdfs:subClassOf obo:VO_0000006 .

obo:VO_0003038 a rdfs:Class ;
  rdfs:label "protein vaccine stabilizer" ;
  rdfs:comment "a vaccine stabilizer that is a protein." ;
  rdfs:subClassOf obo:VO_0000853 .

obo:VO_0003525 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0003523 , obo:VO_0004914 .

obo:VO_0011024 a rdfs:Class ;
  rdfs:label "AroA" ;
  rdfs:comment "The aroA gene of A. salmonicida was cloned in Escherichia coli, and the nucleotide sequence was determined.  Vaccination of brown trout with 10(7) CFU of A. salmonicida 644Rb aroA by intraperitoneal injection resulted in a 253-fold increase in the 50% lethal dose (LD50) compared with unvaccinated controls challenged with a virulent clinical isolate 9 weeks later [PubMed: 8478107]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010814 .

obo:VO_0020715 a rdfs:Class ;
  rdfs:label "BCG, live, Connaught strain 20000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020714 , obo:VO_0020735 .

obo:VO_0003467 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated Injection" ;
  rdfs:subClassOf obo:VO_0003468 .

obo:VO_0011298 a rdfs:Class ;
  rdfs:label "T. cruzi G4" ;
  rdfs:comment "The vaccine efficacy of a  putative candidate antigen against T. cruzi infection and disease in a mouse model. C57BL/6 mice vaccinated with a T. cruzi G4-encoding plasmid and cytokine (interleukin-12 and granulocyte-macrophage colony-stimulating factor) expression plasmids elicited a strong Th1-type antibody response dominated by immunoglobulin G2b (IgG2b)/IgG1 isotypes. The dominant IgG2b/IgG1 antibody response was maintained after a challenge infection and was associated with 90% control of the acute-phase tissue parasite burden and an almost undetectable level of tissue parasites during the chronic phase, as determined by a sensitive T. cruzi 18S rRNA gene-specific real-time PCR approach [PubMed: 18550728]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0016822 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0016733 , obo:VO_0016771 .

obo:VO_0010715 a rdfs:Class ;
  rdfs:label "Hiberix vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000662 , obo:VO_0000714 , obo:VO_0001214 , obo:VO_0010437 .

obo:VO_0000932 a rdfs:Class ;
  rdfs:label "canine coronavirus vaccine" ;
  rdfs:subClassOf obo:VO_0004897 .

obo:VO_0007242 a rdfs:Class ;
  rdfs:label "ALVAC-CEA (VCP248) vaccine" ;
  rdfs:comment "A replication-defective recombinant canarypox virus (ALVAC) that contains the entire human carcinoembryonic antigen (CEA) gene. Vaccination with ALVAC-CEA (VCP248) may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against CEA-positive tumor cells, thereby decreasing tumor growth. (NCI04)" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0007107 a rdfs:Class ;
  rdfs:label "Sargramostim Plasmid DNA Melanoma Vaccine Adjuvant" ;
  rdfs:comment "A vaccine adjuvant consisting of a plasmid DNA encoding sargramostim (a granulocyte macrophage-colony stimulating factor). Upon administration, expressed sargramostim may stimulate a cytotoxic T cell response enhancing the host immune response to a concomitantly administered melanoma vaccine." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0002847 a rdfs:Class ;
  rdfs:label "Francisella tularensis IglB mutant vaccine" ;
  rdfs:comment "Intranasal vaccination with KKF235 (F. tularensis subsp. novicida mutant (DeltaiglB) ) protected mice from subsequent homotypic challenge with U112 as well as heterotypic challenge with F. tularensis subsp. holarctica (LVS). Most significantly, oral immunization with KKF235 protected mice from a highly lethal subsp. tularensis (SCHU S4) pulmonary challenge" ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0005362 a rdfs:Class ;
  rdfs:label "Montanide ISA 206 vaccine adjuvant" ;
  rdfs:comment "A water-dispersed liquid nanoparticle combined with an immuno-stimulating compound." ;
  rdfs:subClassOf obo:VO_0001271 .

obo:VO_0007292 a rdfs:Class ;
  rdfs:label "Autologous EBV-Transformed B Lymphoblastoid-Tumor Fusion Cell Vaccine" ;
  rdfs:comment "A cell-based vaccine composed of autologous tumor cells with Epstein-Barr virus-transformed B-lymphoblastoid cells. Upon administration, this vaccine may stimulate a cytotoxic T cell response against tumor cells, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0007187 a rdfs:Class ;
  rdfs:label "117-126:FGF-5 Peptide Vaccine" ;
  rdfs:comment "A fragment of fibroblast growth factor-5 (FGF-5). Originally isolated from a renal cell carcinoma cell line that overexpressed FGF-5, FGF-5:117-126 peptide is recognized by tumor infiltrating cytotoxic T lymphocytes. Overexpressed by several cancer cell types, this peptide is being tested as a potential target for antineoplastic immunotherapies. (NCI04)" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0002965 a rdfs:Class ;
  rdfs:label "obsolete Feline infectious peritonitis virus 7ab mutant vaccine" ;
  rdfs:comment "A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens" .

obo:VO_0003591 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML [Fluzone 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003589 .

obo:VO_0018468 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0018454 .

obo:VO_0015175 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015148 , obo:VO_0015242 .

obo:VO_0017232 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / Bordetella pertussis / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Boostrix]" ;
  rdfs:subClassOf obo:VO_0000015 , obo:VO_0017230 .

obo:VO_0000250 a rdfs:Class ;
  rdfs:label "pcREV DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002357 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Mannheimia Haemolytica Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0001523 , obo:VO_0002358 .

obo:OPL_0000404 a rdfs:Class ;
  rdfs:label "Plasmodium chabaudi sporozoite stage" ;
  rdfs:comment "A sporozoite stage in the Plasmodium chabaudi." ;
  rdfs:subClassOf obo:OPL_0000152 , obo:OPL_0000300 , obo:OPL_0000416 .

obo:VO_0002268 a rdfs:Class ;
  rdfs:label "Encephalomyelitis Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.27)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000541 , obo:VO_0000640 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0007748 .

obo:VO_0010020 a rdfs:Class ;
  rdfs:label "Leishmania  donovani NH36" ;
  rdfs:comment "A NH36 protein that is part of Leishmania  donovani" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0015156 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:OPL_0000060 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum schizont" ;
  rdfs:comment "A Plasmodium falciparum divides through schizogony. Depending on its location, it is either called hepatic or erythrocytic schizont. The schizont is a dividing stage with 2 or more nuclei." ;
  rdfs:subClassOf obo:NCBITaxon_5833 , obo:OPL_0000275 .

obo:VO_0018406 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 19F vaccine 0.006 MG/ML" ;
  rdfs:subClassOf obo:VO_0003224 .

obo:VO_0010326 a rdfs:Class ;
  rdfs:label "Varicella zoster virus glycoprotein E vaccine" ;
  rdfs:subClassOf obo:VO_0000669 .

obo:VO_0015056 a rdfs:Class ;
  rdfs:label "Mumps Virus Vaccine Live, Jeryl Lynn Strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010442 .

obo:VO_0007173 a rdfs:Class ;
  rdfs:label "Renal Cell Carcinoma/CD40L RNA-Transfected Autologous Dendritic Cell Vaccine AGS-003" ;
  rdfs:comment "A cell-based preparation in which autologous, mature dendritic cells (DCs) are electroporated with in vitro transcribed (IVT) RNAs encoding for a synthetic form of T-cell protein CD40 ligand (CD40L) and IVT RNA encoding for autologous tumor-associated antigens (TAAs) derived from patient-specific bladder cell carcinoma (BCC) cells, with potential immunostimulatory and antineoplastic activities. Upon electroporation into autologous DCs, the RNA is translated and processed. BCC-specific antigenic peptides are subsequently presented via major histocompatibility complex (MHC) Class I molecules on the DCs surface. When AGS-003-BLD is reintroduced to the patient, the MHC-presented peptides interact with and activate CD8-positive T cells, which elicits a highly specific cytotoxic T-cell (CTL) response against tumor cells expressing the patient-specific BCC TAAs. The signal cascade initiated by expression of the co-stimulatory molecule CD40L results in the secretion of the inflammatory cytokine IL-12, which further stimulates CTLs." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0019930 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Prefilled Syringe [Fluzone High-Dose 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0010418 , obo:VO_0019923 .

obo:VO_0001370 a rdfs:Class ;
  rdfs:label "formalin-killed vaccine" ;
  rdfs:comment "an inactivation vaccine that is prepared by formalin inactivation." ;
  rdfs:subClassOf obo:VO_0000017 .

obo:VO_0003536 a rdfs:Class ;
  rdfs:label "Bacillus vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Bacillus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003555 .

obo:VO_0007152 a rdfs:Class ;
  rdfs:label "PSA-PAP/KLH-pulsed Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with the prostate-specific tumor associated antigens (TAAs) prostate specific antigen (PSA) and prostate acid phosphatase (PAP), and conjugated to the immunostimulant keyhole limpet hemocyanin (KLH), with potential immunostimulatory and antineoplastic activities. Upon administration, prostate cancer antigen/KLH-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against prostate cancer cells expressing PSA and PAP, which may result in prostate cancer cell lysis. KLH is an immunogenic carrier and serves as an immunostimulant to improve antigenic immune recognition and T-cell responses and can be used to evaluate vaccine efficacy." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0003111 a rdfs:Class ;
  rdfs:label "Mumpsvax II vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010442 .

obo:VO_0001563 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0000987 , obo:VO_0001220 .

obo:VO_0017926 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide Injectable Solution [Mengivac]" ;
  rdfs:subClassOf obo:VO_0017821 .

obo:VO_0010041 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum EBA-175 RII" ;
  rdfs:comment "A EBA-175 RII protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0017858 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.008 MG/ML" ;
  rdfs:subClassOf obo:VO_0004886 .

obo:VO_0001448 a rdfs:Class ;
  rdfs:label "West Nile virus gene" ;
  rdfs:comment "A viral gene that is from West Nile virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0000573 a rdfs:Class ;
  rdfs:label "Chlamydia vaccine" ;
  rdfs:comment "A vaccine that protects against Chlamydia bacterial infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0010135 a rdfs:Class ;
  rdfs:label "Respiratory syncytial virus (RSV), vaccine, recombinant, protein subunit RSV prefusion F, adjuvant reconstituted, 0.5 mL, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000534 , obo:VO_0000635 , obo:VO_0000753 .

obo:VO_0020556 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluarix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020551 .

obo:VO_0019609 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluad Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020312 .

obo:VO_0005230 a rdfs:Class ;
  rdfs:label "COVID-eVax vaccine" ;
  rdfs:comment "A SARS-CoV-2 plasmid DNA vaccine manufactured by Takis and Rottapharm Biotech" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:VO_0018427 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:VO_0003878 a rdfs:Class ;
  rdfs:label "Flublok 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000978 , obo:VO_0010416 .

obo:VO_0018581 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 467000 PFU/ML Oral Suspension [Rotarix] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018580 .

obo:VO_0010453 a rdfs:Class ;
  rdfs:label "licensed human streptococcus pneumoniae vaccine" ;
  rdfs:comment "Streptococcus pneumoniae vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000675 .

obo:VO_0001591 a rdfs:Class ;
  rdfs:label "avian influenza H3N4 Subtype, Killed Virus Vaccine (USDA: 1057.H3)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001024 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0018348 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003337 .

obo:VO_0002437 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Vaccine" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0000573 , obo:VO_0002436 .

obo:VO_0020244 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0016764 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0016718 .

obo:VO_0016533 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 1 by Europharma" ;
  rdfs:subClassOf obo:VO_0016061 .

obo:OPL_0000376 a rdfs:Class ;
  rdfs:label "Neospora caninum lifecycle stage" ;
  rdfs:comment "A lifecycle stage of Neospora caninum." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:OPL_0000270 a rdfs:Class ;
  rdfs:label "Plasmodium merozoite" ;
  rdfs:comment "A Plasmodium that is during merozoite lifecycle stage, occurs in the bloodstream of a vertebrate host." ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:NCBITaxon_3073809 a rdfs:Class ;
  rdfs:label "Australaves" ;
  rdfs:subClassOf obo:NCBITaxon_8825 .

obo:VO_0003185 a rdfs:Class ;
  rdfs:label "HIB Polysaccharide vaccine foreign to USA" ;
  rdfs:comment "A Haemophilis influenzae Type b capsular polysaccharide vaccine manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0000627 , obo:VO_0003444 .

obo:VO_0004202 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum Tarp subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012176 .

obo:VO_0011078 a rdfs:Class ;
  rdfs:label "FopA" ;
  rdfs:comment "Anti-FopA MAbs protected 90% of nave C3H/HeN mice from lethal challenge with F. tularensis LVS when administered prophylactically as well as therapeutically [PubMed: 19176692]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010760 .

obo:VO_0001067 a rdfs:Class ;
  rdfs:label "herpesvirus of turkey vaccine vector" ;
  rdfs:subClassOf obo:VO_0000283 .

obo:VO_0004896 a rdfs:Class ;
  rdfs:label "intersex biological sex datum" ;
  rdfs:comment "A biological sex datum that represents the biological sex of an animal (including human) as being intersex." ;
  rdfs:subClassOf obo:VO_0001194 .

obo:VO_0001528 a rdfs:Class ;
  rdfs:label "Duck hepatitis virus 1 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Duck hepatitis virus 1 (Duck hepatitis A virus) infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 , obo:VO_0001469 .

obo:VO_0004783 a rdfs:Class ;
  rdfs:label "rPIV5-H3 (influenza virus) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0001333 a rdfs:Class ;
  rdfs:label "ISCOMATRIX vaccine adjuvant" ;
  rdfs:comment "A particulate antigen delivery system vaccine adjuvant that is a vaccine adjuvant comprising cholesterol, phospholipid and saponin but without antigen." ;
  rdfs:subClassOf obo:VO_0001356 .

obo:CHEBI_17992 a rdfs:Class ;
  rdfs:label "sucrose" ;
  rdfs:comment "A glycosyl glycoside formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:VO_0020694 a rdfs:Class ;
  rdfs:label "Antigens Surface Of Virus Influenza, strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain A / Switzerland / 9715293/2013, Nib-88" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010303 , obo:VO_0010415 .

obo:VO_0002505 a rdfs:Class ;
  rdfs:label "Aeromonas hydrophila vaccine" ;
  rdfs:comment "Aeromonas vaccine that protects against Aeromonas hydrophila infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000589 .

obo:DOID_3571 a rdfs:Class ;
  rdfs:label "liver cancer"@en ;
  rdfs:comment "A hepatobiliary system cancer that is located_in the liver."@en ;
  rdfs:subClassOf obo:DOID_0080355 , obo:DOID_170 , obo:DOID_3118 .

obo:VO_0019917 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Injectable Suspension [Afluria 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019916 , obo:VO_0020300 .

obo:VO_0010926 a rdfs:Class ;
  rdfs:label "ABRA" ;
  rdfs:comment "Protective antigen [PubMed: 11489167]" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010771 .

obo:NCBITaxon_38525 a rdfs:Class ;
  rdfs:label "avian metapneumovirus" ;
  rdfs:subClassOf obo:NCBITaxon_162387 .

obo:VO_0003377 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain Injection [Stamaril]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0003139 .

obo:VO_0010277 a rdfs:Class ;
  rdfs:label "assay analysis tool version datum" ;
  rdfs:comment "A measurment datum that records the version of an analysis tool (software) used for an assay." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0010752 a rdfs:Class ;
  rdfs:label "G+ bacterium protein" ;
  rdfs:subClassOf obo:VO_0010751 .

obo:VO_0019536 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine Injection [Prehevbrio]" ;
  rdfs:subClassOf obo:VO_0003421 .

obo:VO_0015300 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015298 .

obo:VO_0017355 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Hibdpt Vaccinol]" ;
  rdfs:subClassOf obo:VO_0017349 .

obo:VO_0020501 a rdfs:Class ;
  rdfs:label "influenza A virus as vaccine component" ;
  rdfs:subClassOf obo:VO_0000420 .

obo:VO_0003737 a rdfs:Class ;
  rdfs:label "Afluria 2018-2019 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003734 .

obo:VO_0020300 a rdfs:Class ;
  rdfs:label "Afluria 2012-2013 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000006 , obo:VO_0000578 , obo:VO_0010418 .

obo:VO_0005275 a rdfs:Class ;
  rdfs:label "Th2 immunity stimulatory role" ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0018774 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.008 MG / Bordetella pertussis 0.05 MG / diphtheria toxoid vaccine, inactivated 30 UNT / tetanus toxoid vaccine, inactivated 40 UNT" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0000108 a rdfs:Class ;
  rdfs:label "Brucella abortus vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000025 .

obo:VO_0021171 a rdfs:Class ;
  rdfs:label "0.3 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (XBB.1.5) 0.1 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0021170 .

obo:VO_0017626 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017610 .

obo:VO_0007325 a rdfs:Class ;
  rdfs:label "allogeneic HLA-A2/4-1BB ligand-expressing melanoma vaccine" ;
  rdfs:comment "A cancer vaccine that consists of an allogeneic cell line that has a high expression level of melanoma molecules (HLA A2/4-1BB Ligand), and has been genetically modified to induce a strong immune response. Stimulation of the immune response against the tumor can help destroy residual tumor in melanoma patients with very high risk for disease recurrence and in patients with relatively low tumor burden who already got first line treatment for their disease." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0018417 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 9V vaccine 0.001 MG" ;
  rdfs:subClassOf obo:VO_0003561 .

obo:VO_0003258 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0015019 .

obo:VO_0000615 a rdfs:Class ;
  rdfs:label "vaccine role" ;
  rdfs:comment "Role that inheres in a prepared material entity that is designed to induce protection or treatment for a disease or infection. " ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0020158 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0020157 .

obo:VO_0003618 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003616 .

obo:VO_0011017 a rdfs:Class ;
  rdfs:label "Caf1 from Y. pestis" ;
  rdfs:comment "Vaccination of mice with deF1 DNA conferred protection against subcutaneous infection with the virulent Y. pestis Kimberley53 strain, even at challenge amounts as high as 4,000 50% lethal doses [PubMed: 12496187 ]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0010871 a rdfs:Class ;
  rdfs:label "L1R from Monkeypox virus Zaire-96-I-16" ;
  rdfs:comment "It has previously been shown that a DNA subunit vaccine (4pox) based on four orthopoxvirus immunogens (L1R, B5R, A27L and A33R) can produce protective immunity against lethal orthopoxvirus challenges in mice and nonhuman primates. the immunogenicity of an L1R construct to which a tissue plasminogen activator signal sequence was placed in frame with the full-length L1R gene was tested. When the tPA-L1R construct was substituted for the unmodified L1R gene in the 4pox vaccine, given as a prime and single boost, animals were better protected from lethal challenge with vaccinia virus (VACV) [PubMed: 18485547]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010764 .

obo:VO_0011491 a rdfs:Class ;
  rdfs:label "Trypanosoma brucei DNA vaccine encoding TSA protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012184 .

obo:VO_0007404 a rdfs:Class ;
  rdfs:label "hTERT vaccine V934/V935" ;
  rdfs:comment "Gene name: TERT" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0007044 a rdfs:Class ;
  rdfs:label "SVN53-67/M57-KLH peptide vaccine" ;
  rdfs:comment "A peptide vaccine containing a 15-mer peptide (DLAQMFFCFKELEGW), with C to M alteration at amino acid position 57, derived from the anti-apoptosis protein survivin, and conjugated with keyhole limpet hemocyanin (KLH), with potential immunopotentiating and antineoplastic activities. Upon subcutaneous administration of SVN53-67/M57-KLH peptide vaccine, this peptide is able to bind both HMC class I and II molecules and may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) as well as a T-helper cell response against survivin-expressing cancer cells. This may result in decreased tumor cell proliferation and ultimately tumor cell death. Survivin, a member of the inhibitor of apoptosis (IAP) family, expressed during embryonic development while absent in most normal adult cells, is upregulated in a variety of human cancers; its expression in tumors is associated with a more aggressive phenotype, decreased survival, and increased resistance to chemotherapy. KLH may enhance immune recognition and may promote an enhanced response. As SVN53-67 is weakly immunogenic in humans, the M57 alteration may lead to greater affinity towards HLA-A*0201 and thus an enhanced antitumor immune response." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0005492 , obo:VO_0007657 .

obo:VO_0002927 a rdfs:Class ;
  rdfs:label "Shigella sonnei virG/senA/senB/msbB2 mutant vaccine" ;
  rdfs:comment "A virG, senA, senB, and msbB2 mutant (WRSs3) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs3 is comparable to live attenuated vaccine strain WRSS1" ;
  rdfs:subClassOf obo:VO_0000679 .

obo:VO_0000336 a rdfs:Class ;
  rdfs:label "pVR1012x/s DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0002228 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J8.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002412 , obo:VO_0007748 .

obo:VO_0002043 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1288.42)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0004238 a rdfs:Class ;
  rdfs:label "gp140, Gag and Tat protein vaccine with MF59" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0019957 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Fluvirin 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019952 , obo:VO_0020477 .

obo:VO_0015774 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe Box of 25" ;
  rdfs:subClassOf obo:VO_0015489 .

obo:VO_0000562 a rdfs:Class ;
  rdfs:label "therapeutic vaccine function" ;
  rdfs:comment "A vaccine function realized the process of vaccination and leading to induction of an adaptive immune response to treat an existing specific disorder." ;
  rdfs:subClassOf obo:VO_0000278 .

obo:VO_0020283 a rdfs:Class ;
  rdfs:label "varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0003803 , obo:VO_0020281 .

obo:NCBITaxon_40050 a rdfs:Class ;
  rdfs:label "Orbivirus alphaequi" ;
  rdfs:subClassOf obo:NCBITaxon_10892 .

obo:VO_0017369 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Revaxis]" ;
  rdfs:subClassOf obo:VO_0003095 , obo:VO_0017368 .

obo:VO_0004511 a rdfs:Class ;
  rdfs:label "Chinese Schistosoma japonicum DNA vaccine SjC23-Hsp70" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001229 .

obo:VO_0016740 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Covaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0016708 , obo:VO_0016768 .

obo:VO_0002443 a rdfs:Class ;
  rdfs:label "fowlpox-Laryngotracheitis vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000985 , obo:VO_0001468 , obo:VO_0001488 .

obo:VO_0000408 a rdfs:Class ;
  rdfs:label "organ or tissue specific immune response to vaccine" ;
  rdfs:subClassOf obo:VO_0000287 .

obo:VO_0007141 a rdfs:Class ;
  rdfs:label "VEGFR1-1084 Peptide Vaccine" ;
  rdfs:comment "A peptide vaccine containing an HLA-A*2402-restricted epitope of vascular endothelial growth factor receptor 1 (VEGFR1 or Flt-1) with potential immunostimulating, antiangiogenic, and antineoplastic activities. Upon vaccination, VEGFR1-1084 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against VEGFR1-expressing endothelial cells of the tumor microvasculature, which may inhibit tumor angiogenesis and tumor cell proliferation. VEGFR1, a receptor tyrosine kinase, may be overexpressed on endothelial cells of the tumor microvasculature and is associated with tumor cell proliferation, invasion and tumor angiogenesis. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenicity." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005430 , obo:VO_0007657 .

obo:VO_0017418 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux]" ;
  rdfs:subClassOf obo:VO_0017381 , obo:VO_0017417 .

obo:VO_0002145 a rdfs:Class ;
  rdfs:label "Marek's Disease-Newcastle Disease Serotypes 1 & 2 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 16N1.R2)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002447 , obo:VO_0007748 .

obo:VO_0007445 a rdfs:Class ;
  rdfs:label "human papillomavirus  16 L1-VLP vaccine" ;
  rdfs:comment "A vaccine consisting of human papillomavirus-derived noninfectious virus-like particles (VLPs), containing the L. major capsid protein. Vaccination with HPV 16 L1-VLP results in increases in T cell-proliferative response to HPV 16 L1-VLP, as well as significant increases in cytokine (interferon-gamma, interleukin-5 and -10) responses to L1 VLP. This agent may reduce the incidence of persistent HPV-16 infection, which may be responsible for half of all cases of cervical cancer including high-grade cervical intraepithelial neoplasia." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000667 , obo:VO_0007656 .

obo:VO_0016976 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.02 MG/ML Injection [Hiberix]" ;
  rdfs:subClassOf obo:VO_0010436 , obo:VO_0016975 , obo:VO_0017439 .

obo:VO_0003278 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 20000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0006060 a rdfs:Class ;
  rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 100 mcg/0.5mL dose or 50 mcg/0.25mL dose" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0017776 a rdfs:Class ;
  rdfs:label "Bordetella Pertussis Fimbriae Serotype 2 And 3 Antigen" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0003290 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0088 MG/ML" ;
  rdfs:subClassOf obo:VO_0003345 .

obo:VO_0018457 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 1" ;
  rdfs:subClassOf obo:VO_0018433 , obo:VO_0018441 .

obo:OAE_0000004 a rdfs:Class ;
  rdfs:label "vaccine adverse event" ;
  rdfs:comment "an adverse event that occurs after a vaccination." ;
  rdfs:subClassOf obo:OAE_0000001 .

obo:VO_0000216 a rdfs:Class ;
  rdfs:label "pCMV-1 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:NCBITaxon_197 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni" ;
  rdfs:subClassOf obo:NCBITaxon_194 .

obo:NCBITaxon_1980442 a rdfs:Class ;
  rdfs:label "Orthohantavirus" ;
  rdfs:subClassOf obo:NCBITaxon_1980410 .

obo:BFO_0000140 a rdfs:Class ;
  rdfs:label "continuant fiat boundary"@en ;
  rdfs:comment "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:VO_0003057 a rdfs:Class ;
  rdfs:label "obsolete augmented protection and cellular immunity using host protein as adjuvant" ;
  rdfs:comment "An vaccine-induced host response that shows augmented protection and cellular immunity after a host protein is used as adjuvant. " .

obo:VO_0000249 a rdfs:Class ;
  rdfs:label "vaccine-induced antiviral neutralizing antibody response" ;
  rdfs:subClassOf obo:VO_0000632 .

obo:VO_0003238 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [Recombivax]" ;
  rdfs:subClassOf obo:VO_0003237 .

obo:VO_0007203 a rdfs:Class ;
  rdfs:label "Adenovirus B7-1 vaccine" ;
  rdfs:comment "A gene-viral vector complex comprised of an adenovirus vector and B7-1 gene targeting the CD80 antigen. Adenovirus B7-1 is used as a component in antineoplastic vaccines to elicit a cytotoxic T-cell response." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0002291 a rdfs:Class ;
  rdfs:label "Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4960.00)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002463 , obo:VO_0007748 .

obo:VO_0001767 a rdfs:Class ;
  rdfs:label "Rabies Live Vaccinia Vector Vaccine (USDA: 1901.R0)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0018491 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 20 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0018459 .

obo:VO_0017985 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.5 MG / meningococcal group C polysaccharide 0.5 MG Injectable Solution by Aventis" ;
  rdfs:subClassOf obo:VO_0017956 .

obo:VO_0016492 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Mtk" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0001976 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B9.22)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002360 .

obo:VO_0019412 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain Injection" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0019465 .

obo:NCBITaxon_29546 a rdfs:Class ;
  rdfs:label "Lawsonia intracellularis" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:VO_0016031 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015668 , obo:VO_0015783 .

obo:VO_0016811 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] Box of 50" ;
  rdfs:subClassOf obo:VO_0016729 , obo:VO_0016753 , obo:VO_0016827 .

obo:VO_0012364 a rdfs:Class ;
  rdfs:label "Ag85B from M. tuberculosis H37Rv" ;
  rdfs:comment "In mice, a primary vaccination with Ag85B-encoding plasmid DNA (DNA-85B) was protective against Mycobacterium tuberculosis (MTB) infection and associated with Ag85B-specific CD4+ T cells producing IFN-gamma and controlling intramacrophagic MTB growth [PubMed: 17250590]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0011470 a rdfs:Class ;
  rdfs:label "Eimeria tenella GX3262 protein vaccine" ;
  rdfs:subClassOf obo:VO_0001137 .

obo:VO_0011311 a rdfs:Class ;
  rdfs:label "E protein from Dengue virus" ;
  rdfs:comment "A recombinant baculovirus encoding a dengue (DEN)-2 virus envelope glycoprotein truncated of 102 amino acids (aa) at its C-terminus (D2EA102) was constructed. Both intracellular and extracellular D2EA102 induced neutralizing antibodies in mice and were thus immunogenic. Sixty eight percent (P < 0.001) of mice vaccinated with 5 gg of extracellular D2EA102 protein were protected against lethal challenge [PubMed: 7826210]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010844 .

obo:VO_0000192 a rdfs:Class ;
  rdfs:label "Montanide 103 vaccine adjuvant" ;
  rdfs:comment "A Montanide vaccine adjuvant that is Montanide 103." ;
  rdfs:subClassOf obo:VO_0001271 .

obo:VO_0007611 a rdfs:Class ;
  rdfs:label "hapten dinitrophenyl vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0016753 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] Box of 50" ;
  rdfs:subClassOf obo:VO_0016714 , obo:VO_0016776 .

obo:VO_0019793 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003767 .

obo:VO_0016265 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 3 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015922 .

obo:VO_0004735 a rdfs:Class ;
  rdfs:label "ALVAC-EIV (equine influenza virus H3N8) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0015903 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 50" ;
  rdfs:subClassOf obo:VO_0015624 , obo:VO_0016018 .

obo:VO_0000712 a rdfs:Class ;
  rdfs:label "inactivated viral vaccine" ;
  rdfs:comment "a viral vaccine that is inactivated" ;
  rdfs:subClassOf obo:VO_0000315 , obo:VO_0000609 .

obo:VO_0018275 a rdfs:Class ;
  rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003857 .

obo:VO_0005459 a rdfs:Class ;
  rdfs:label "Diphtheria, tetanus toxoids and acellular pertussis vaccine, unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000738 .

obo:VO_0019569 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Fluvirin 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003687 , obo:VO_0019544 .

obo:GO_0050896 a rdfs:Class ;
  rdfs:label "response to stimulus" ;
  rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:VO_0003585 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML [Fluzone 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003584 .

obo:VO_0017924 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide Injectable Solution [AC Vax]" ;
  rdfs:subClassOf obo:VO_0017821 .

obo:VO_0019338 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML Injection [Menactra]" ;
  rdfs:subClassOf obo:VO_0000071 , obo:VO_0000561 .

obo:VO_0017135 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017133 , obo:VO_0017143 , obo:VO_0017599 .

obo:VO_0016544 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015984 .

obo:VO_0011416 a rdfs:Class ;
  rdfs:label "Entamoeba histolytica SREHP protein vaccine" ;
  rdfs:subClassOf obo:VO_0012171 .

obo:VO_0018207 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 TCID / Mumps virus 12500 TCID / Rubella virus 1000 TCID Injection" ;
  rdfs:subClassOf obo:VO_0018245 .

obo:VO_0003889 a rdfs:Class ;
  rdfs:label "Flublok 2015-2016 vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003887 .

obo:VO_0015510 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Engerix B]" ;
  rdfs:subClassOf obo:VO_0003256 , obo:VO_0010711 .

obo:VO_0016416 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 3 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015960 , obo:VO_0015966 .

obo:VO_0018022 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018046 .

obo:VO_0003113 a rdfs:Class ;
  rdfs:label "Tetracoq vaccine" ;
  rdfs:comment "An adsorbed diphtheria, tetanus, pertussis and inactivated poliomyelitis vaccine." ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0000640 , obo:VO_0000664 , obo:VO_0000712 , obo:VO_0000735 , obo:VO_0000765 , obo:VO_0001214 .

obo:VO_0003827 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML [Havrix]" ;
  rdfs:subClassOf obo:VO_0000052 , obo:VO_0003431 .

obo:VO_0015771 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015594 .

obo:VO_0017344 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Pertussis Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0016284 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0016026 .

obo:VO_0005059 a rdfs:Class ;
  rdfs:label "pWRG7079 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pWRG7079.  This plasmid contains a CMV promoter and a kanamycin resistance gene and differs from pWRG7077 by the insertion of a TPA sequence." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0018648 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018797 .

obo:VO_0000273 a rdfs:Class ;
  rdfs:label "vaccine-induced T cell interferon-gamma production" ;
  rdfs:subClassOf obo:VO_0000593 .

obo:VO_0015727 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Hepasorbat] Box of 10" ;
  rdfs:subClassOf obo:VO_0015575 , obo:VO_0015795 .

obo:VO_0019643 a rdfs:Class ;
  rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010432 .

obo:VO_0011293 a rdfs:Class ;
  rdfs:label "T. cruzi Cruzipain" ;
  rdfs:comment "To study the protective effects in vivo of cruzipain-specific Th1 responses against systemic T. cruzi challenges, mice  were immunized with recombinant cruzipain plus interleukin 12 (IL-12) and a neutralizing anti-IL-4 MAb. These immunized mice developed potent cruzipain-specific memory Th1 cell responses and were significantly protected against normally lethal systemic T. cruzi challenges. To study whether cruzipain could induce mucosal immune responses relevant for vaccine development, recombinant attenuated Salmonella enterica serovar Typhimurium vaccines expressing cruzipain were prepared. BALB/c mice immunized with salmonella expressing cruzipain were significantly protected against T. cruzi mucosal infection [PubMed: 12183554]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0010712 a rdfs:Class ;
  rdfs:label "Eolarix vaccine" ;
  rdfs:comment "A Measles-Rubella vaccine that is live attenuated and manufactured by GlaxoSmithKline Biologicals." ;
  rdfs:subClassOf obo:VO_0000714 , obo:VO_0000945 , obo:VO_0001220 .

obo:VO_0020052 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0017728 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 600 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017795 .

obo:VO_0011197 a rdfs:Class ;
  rdfs:label "PsrP" ;
  rdfs:comment "Mice immunized with recombinant (r)PsrP(BR) had significantly less bacteria in their blood and improved survival versus controls following intranasal challenge [PubMed: 19627498]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010779 .

obo:VO_0000033 a rdfs:Class ;
  rdfs:label "Diphtheria and Tetanus Toxoids Adsorbed USP vaccine by Sanofi Pasteur Inc" ;
  rdfs:comment "Product Name: Diphtheria & Tetanus Toxoids Adsorbed" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0007062 a rdfs:Class ;
  rdfs:label "Quadrivalent Human Papillomavirus (types 6, 11, 16, 18) Recombinant Vaccine" ;
  rdfs:comment "A non-infectious recombinant, quadrivalent vaccine prepared from the highly purified virus-like particles (VLPs) of the major capsid (L1) protein of human papillomavirus (HPV) Types 6, 11, 16, and 18 with immunoprophylactic activity. The immunoprohylactic efficacy of L1 VLP vaccines, such as recombinant human papillomavirus quadrivalent vaccine, appear to be mediated by the development of humoral immune responses. HPV Types 16 and 18 account for approximately 70% of cervical cancers and HPV Types 6 and 11 account for approximately 90% of genital warts." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005488 , obo:VO_0007657 .

obo:VO_0015828 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] by GSK" ;
  rdfs:subClassOf obo:VO_0015622 , obo:VO_0015623 .

obo:VO_0017825 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML [ActHIB]" ;
  rdfs:subClassOf obo:VO_0000004 , obo:VO_0010444 , obo:VO_0017850 .

obo:VO_0018337 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Prefilled Syringe [Rabipur] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018322 .

obo:VO_0016571 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Hepatitis B Surface Antigen Vaccine Injectable Solution [Twinrix Adult]" ;
  rdfs:subClassOf obo:VO_0016579 .

obo:VO_0002502 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus vaccine" ;
  rdfs:comment "A bacterial vaccine that protects against infection with Staphylococcus aureus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000770 .

obo:VO_0015681 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe [H B Vax] Box of 50" ;
  rdfs:subClassOf obo:VO_0015563 , obo:VO_0015775 .

obo:VO_0020464 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0020447 .

obo:VO_0004499 a rdfs:Class ;
  rdfs:label "avian influenza virus DNA vaccine pNP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0001607 a rdfs:Class ;
  rdfs:label "Avian Reovirus Killed Virus Vaccine (USDA: 1045.01)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001513 , obo:VO_0007748 .

obo:VO_0003976 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Kinrix]" ;
  rdfs:subClassOf obo:VO_0000067 .

obo:VO_0007462 a rdfs:Class ;
  rdfs:label "bivalent neuroblastoma vaccine with adjuvant OPT-821" ;
  rdfs:comment "A cancer vaccine that is a bivalent vaccine with the antigens GD2L and GD3L for patients with High-Risk Neuroblastoma. The antigens are linked to KLH and mixed with OPT-821. It is given in combination with oral β-glucan, which can help white blood cells kill cancer." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0007657 .

obo:VO_0002916 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium znuABC mutant vaccine" ;
  rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" .

obo:VO_0003196 a rdfs:Class ;
  rdfs:label "inactivated acellular pertussis vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0001214 , obo:VO_0003389 , obo:VO_0010435 .

obo:VO_0003247 a rdfs:Class ;
  rdfs:label "vaccination site" ;
  rdfs:comment "The site that is the part of the host body and the entrance point where a vaccine is administered. " ;
  rdfs:subClassOf obo:BFO_0000029 .

obo:VO_0019384 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0002267 a rdfs:Class ;
  rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.26)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002420 , obo:VO_0007748 .

obo:VO_0010882 a rdfs:Class ;
  rdfs:label "DnaK from Chlamydophila abortus" ;
  rdfs:comment "In pregnant mice, the dnaK vaccine induced a non-specific partial protection from abortion after challenge with Chlamydophila abortus [PubMed: 12056482]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010817 .

obo:VO_0004850 a rdfs:Class ;
  rdfs:label "Trumenba vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0004849 .

obo:VO_0015772 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0015489 .

obo:VO_0004542 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus DNA vaccine encoding Efb, FnbpA, ClfA, Cna" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002502 .

obo:VO_0003912 a rdfs:Class ;
  rdfs:label "Fluad 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000362 , obo:VO_0004281 , obo:VO_0010433 .

obo:VO_0002134 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis-Influenza Modified Live & Killed Virus Vaccine (USDA: 1518.20)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002421 , obo:VO_0007748 .

obo:VO_0019463 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 4 UNT/ML Injection [Tdvax]" ;
  rdfs:subClassOf obo:VO_0019462 .

obo:VO_0019992 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML [Fluzone Intradermal 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020486 .

obo:VO_0020061 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Injectable Suspension [Fluvirin 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020471 .

obo:VO_0018250 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 5000 UNT / Rubella virus 1000 UNT" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0012178 a rdfs:Class ;
  rdfs:label "canine distemper virus vaccine" ;
  rdfs:comment "A vaccine that protects against Canine distemper virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003543 .

obo:NCBITaxon_333774 a rdfs:Class ;
  rdfs:label "unclassified Papillomaviridae" ;
  rdfs:subClassOf obo:NCBITaxon_151340 .

obo:VO_0016308 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015926 .

obo:VO_0005305 a rdfs:Class ;
  rdfs:label "TLR3 receptor role" ;
  rdfs:comment "A role of a material entity that binds to TLR3 and activates the receptor for pathogen recognition and activation of innate immunity." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0000290 a rdfs:Class ;
  rdfs:label "host response to vaccine component" ;
  rdfs:comment "Process that specifies host response to a vaccine component." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0016290 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0016026 .

obo:DOID_9351 a rdfs:Class ;
  rdfs:label "diabetes mellitus"@en ;
  rdfs:comment "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both."@en ;
  rdfs:subClassOf obo:DOID_4 .

obo:VO_0007726 a rdfs:Class ;
  rdfs:label "PolyPEPI1018 CRC vaccine" ;
  rdfs:comment "A cancer vaccine that contains 6 synthetic peptides mixed with the adjuvant Montanide™. The peptides were selected to induce T cell responses against 12 dominant epitopes from 7 cancer testis antigens (CTAs), which are the most frequently expressed CTAs in colorectal cancer. The 6 peptides were optimized to induce long lasting CRC specific T cell responses. Colorectal cancer peptide vaccine PolyPEPI1018 potentially elicits a cytotoxic T-lymphocyte response against colorectal tumors expressing the CTAs associated with the vaccine, which may result in a reduction in tumor cell proliferation. " ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005426 , obo:VO_0007657 .

obo:UBERON_0004120 a rdfs:Class ;
  rdfs:label "mesoderm-derived structure" ;
  rdfs:comment "An anatomical structure that develops (entirely or partially) from the mesoderm." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:VO_0019107 a rdfs:Class ;
  rdfs:label "0.1 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019995 .

obo:VO_0004355 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pDNA encoding M2 and NP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0004166 a rdfs:Class ;
  rdfs:label "Clostridium botulinum DNA vaccine pSCARSA/BHc" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012187 .

obo:VO_0018760 a rdfs:Class ;
  rdfs:label "yellow fever virus strain 17D-204 live antigen Injectable Suspension [Arilvax]" ;
  rdfs:subClassOf obo:VO_0018808 .

obo:VO_0002386 a rdfs:Class ;
  rdfs:label "Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica vaccine" ;
  rdfs:subClassOf obo:VO_0001490 , obo:VO_0002418 .

obo:NCBITaxon_1236 a rdfs:Class ;
  rdfs:label "Gammaproteobacteria" ;
  rdfs:subClassOf obo:NCBITaxon_1224 .

obo:VO_0002741 a rdfs:Class ;
  rdfs:label "glycoprotein G from Rabies virus" ;
  rdfs:comment "A glycoprotein G mutant in rabies virus is attenuated. After a one-dose intramuscular vaccination, the ERAg3m virus protected 100% of mice and hamsters from lethal challenge. In co-infections, using a lethal dose of street rabies virus mixed with ERAg3m, 100% of hamsters and 90% of mice survived and were protected against subsequent infection" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001443 .

obo:VO_0007393 a rdfs:Class ;
  rdfs:label "Fas-Chimera Transgene-expressing Endothelial Tumor Cell-targeting Adenovector VB-111 Vaccine" ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 .

obo:VO_0015847 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 .

obo:VO_0011473 a rdfs:Class ;
  rdfs:label "Vaxxitek HVT+IBD vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0012162 .

obo:VO_0000474 a rdfs:Class ;
  rdfs:label "killed nontypeable Haemophilus influenzae whole-cell vaccine" ;
  rdfs:subClassOf obo:VO_0000471 .

obo:VO_0001287 a rdfs:Class ;
  rdfs:label "BAY R1005 vaccine adjuvant" ;
  rdfs:comment "A synthetic vaccine adjuvant that is Bay R1005 (N-(2-Deoxy-2-L-leucylamino beta-D-glucopyranosyl)-N-octadecyldodecanoylamide hydroacetate )." ;
  rdfs:subClassOf obo:VO_0001357 .

obo:VO_0007269 a rdfs:Class ;
  rdfs:label "anti-PRAME Immunotherapeutic GSK2302032A Vaccine" ;
  rdfs:comment "An immunotherapeutic agent targeting the tumor-associated antigen (TAA), preferentially expressed antigen of melanoma (PRAME), with potential antineoplastic activity." ;
  rdfs:subClassOf obo:VO_0005486 , obo:VO_0007657 .

obo:NCBITaxon_40119 a rdfs:Class ;
  rdfs:label "Parvovirinae" ;
  rdfs:subClassOf obo:NCBITaxon_2732415 .

obo:VO_0019739 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2023 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020496 .

obo:VO_0004924 a rdfs:Class ;
  rdfs:label "adult age" ;
  rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ;
  rdfs:subClassOf obo:VO_0004921 .

obo:VO_0004564 a rdfs:Class ;
  rdfs:label "SIV recombinant vector vaccine rAd5/rLCMV" ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000751 .

obo:VO_0001698 a rdfs:Class ;
  rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1651.02)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001017 , obo:VO_0007748 .

obo:VO_0004303 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pBK-SFV-NP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0002545 a rdfs:Class ;
  rdfs:label "sigE from Mycobacterium tuberculosis" ;
  rdfs:comment "A sigE mutant is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis, more so than the existing vaccine BCG" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0001632 a rdfs:Class ;
  rdfs:label "Bursal Disease Killed Virus Vaccine (USDA: 1275.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000960 , obo:VO_0007748 .

obo:VO_0001427 a rdfs:Class ;
  rdfs:label "Yersinia pseudotuberculosis gene" ;
  rdfs:comment "A bacterial gene that is from Yersinia pseudotuberculosis." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0007376 a rdfs:Class ;
  rdfs:label "DNA plasmid-encoding Interleukin-12 INO-9012 vaccine" ;
  rdfs:comment "A plasmid DNA vaccine encoding the human pro-inflammatory cytokine interleukin-12 (IL-12) with potential immunoactivating activity. Upon intramuscular delivery by electroporation of DNA plasmid encoding interleukin-12 INO-9012, IL-12 is translated in cells and activates the immune system by promoting the activation of natural killer cells (NK cells), inducing secretion of interferon-gamma and promoting cytotoxic T-cell responses against tumor cells. This may result in both immune-mediated tumor cell death and the inhibition of tumor cell proliferation." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0016296 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 10 by Merck" ;
  rdfs:subClassOf obo:VO_0016027 .

obo:VO_0011186 a rdfs:Class ;
  rdfs:label "ExbB" ;
  rdfs:comment "A total of 11 meningococcal proteins that are necessary for establishing systemic infection were expressed as recombinant antigens and assessed for their ability to protect mice against live bacterial challenge against N. meningitidis; ExbB, which is required for iron acquisition, elicited protective immunity [PubMed: 15964482]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0003306 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 45 Vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003299 , obo:VO_0010446 .

obo:VO_0003819 a rdfs:Class ;
  rdfs:label "influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010315 , obo:VO_0010415 .

obo:VO_0001168 a rdfs:Class ;
  rdfs:label "E. coli FimH with CFA and then IFA vaccine" ;
  rdfs:comment "an E. coli subunit vaccine that uses E. coli FimH adhesin protein as teh antigen, and uses the complete Freund's adjuvant (CFA) in the first vaccination and the incomplete Freund's adjuvant (IFA) in the boost vaccination." ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0017866 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.005 MG" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0002988 a rdfs:Class ;
  rdfs:label "obsolete Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine" ;
  rdfs:comment "A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" .

obo:VO_0007101 a rdfs:Class ;
  rdfs:label "recombinant Fowlpox-Tyrosinase vaccine" ;
  rdfs:comment "A recombinant fowlpox virus vaccine with potential antineoplastic activity. Binding to the melanoma antigen tyrosinase, recombinant fowlpox-tyrosinase vaccine generates cellular immune responses against melanoma cells expressing the tyrosinase antigen; this effect is enhanced by the co-administration of interleukin 2 (IL-2). Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:OBI_0000456 a rdfs:Class ;
  rdfs:label "material transformation objective"@en ;
  rdfs:comment "an objective specifiction that creates an specific output object from input materials."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:VO_0001028 a rdfs:Class ;
  rdfs:label "Leishmania tarentolae vaccine vector" ;
  rdfs:comment "a parasite vaccine vector using a live attenuated Leishmania tarentolae strain.  " ;
  rdfs:subClassOf obo:VO_0001034 .

obo:VO_0003094 a rdfs:Class ;
  rdfs:label "Pnu-Imune vaccine" ;
  rdfs:subClassOf obo:VO_0000675 , obo:VO_0001217 .

obo:VO_0010633 a rdfs:Class ;
  rdfs:label "USA" ;
  rdfs:comment "USA is a country that exists in north America." ;
  rdfs:subClassOf obo:VO_0010632 .

obo:VO_0003838 a rdfs:Class ;
  rdfs:label "PEDIARIX Injectable Product" ;
  rdfs:subClassOf obo:VO_0000082 .

obo:VO_0020769 a rdfs:Class ;
  rdfs:label "BCG, live, Tice strain 12.5 MG Injection [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020759 , obo:VO_0020768 , obo:VO_0020809 .

obo:VO_0004702 a rdfs:Class ;
  rdfs:label "Typhi strain Ty21a-PA Bacillus anthracis vaccine" ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0003959 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 10A vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0018719 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML [Typhim VI]" ;
  rdfs:subClassOf obo:VO_0018717 .

obo:VO_0019289 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003611 .

obo:VO_0000660 a rdfs:Class ;
  rdfs:label "ProHIBiT vaccine" ;
  rdfs:subClassOf obo:VO_0000662 .

obo:VO_0021132 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0020322 .

obo:VO_0018124 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella virus vaccine Injection [M-M-RVAXPRO]" ;
  rdfs:subClassOf obo:VO_0018122 .

obo:VO_0020885 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0020851 .

obo:VO_0019858 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Victoria/1/2020 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML / influenza B virus B/Washington/02/2019 antigen 158000000 UNT/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0015235 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0011354 a rdfs:Class ;
  rdfs:label "Leishmania amazonensis DNA vaccine encoding GP47" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012158 .

obo:VO_0017184 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension Box of 2" ;
  rdfs:subClassOf obo:VO_0017152 , obo:VO_0017627 .

obo:VO_0003227 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 22F vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0017019 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016995 , obo:VO_0017496 .

obo:VO_0000851 a rdfs:Class ;
  rdfs:label "vaccine preservative" ;
  rdfs:comment """Vaccine additive that is added to a vaccine formulation to prevent the growth of bacteria or fungi that inadvertently may be introduced into the vaccine during use.
Ref: Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 73.""" ;
  rdfs:subClassOf obo:VO_0000179 , obo:VO_0000850 .

obo:VO_0004142 a rdfs:Class ;
  rdfs:label "Salmonella vacT vaccine" ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0010355 a rdfs:Class ;
  rdfs:label "PREHEVBRIO vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0010439 .

obo:VO_0000593 a rdfs:Class ;
  rdfs:label "vaccine specific T cell cytokine production" ;
  rdfs:subClassOf obo:VO_0000106 .

obo:VO_0015278 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015275 .

obo:VO_0004415 a rdfs:Class ;
  rdfs:label "West Nile virus DNA vaccine pCBWN encoding prM and E" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000752 .

obo:NCBITaxon_11308 a rdfs:Class ;
  rdfs:label "Orthomyxoviridae" ;
  rdfs:subClassOf obo:NCBITaxon_2497571 .

obo:VO_0011489 a rdfs:Class ;
  rdfs:label "Canine distemper virus DNA vaccine encoding F and HA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012178 .

obo:VO_0016011 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0015662 , obo:VO_0015803 .

obo:VO_0001104 a rdfs:Class ;
  rdfs:label "Rous sarcoma virus vaccine vector" ;
  rdfs:subClassOf obo:VO_0001102 .

obo:VO_0002044 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1288.43)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0003686 a rdfs:Class ;
  rdfs:label "Fluvirin 2016-2017 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003685 .

obo:VO_0004029 a rdfs:Class ;
  rdfs:label "Borrelia burgdorferi OspB protein vaccine" ;
  rdfs:subClassOf obo:VO_0000764 .

obo:VO_0003990 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 .

obo:VO_0003321 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 18C vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003222 .

obo:VO_0000073 a rdfs:Class ;
  rdfs:label "Meruvax II vaccine" ;
  rdfs:comment "Product Name: Rubella Virus Vaccine Live" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010450 , obo:VO_0010637 .

obo:VO_0018637 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Injectable Solution [Japanese encephalitis GCVC]" ;
  rdfs:subClassOf obo:VO_0018635 .

obo:VO_0004861 a rdfs:Class ;
  rdfs:label "meningococcal group C polysaccharide 0.01 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010290 , obo:VO_0010444 .

obo:VO_0018141 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML [Mmr Priorix]" ;
  rdfs:subClassOf obo:VO_0018135 .

obo:VO_0000546 a rdfs:Class ;
  rdfs:label "vaccinee population" ;
  rdfs:comment "a population group that are vaccinated with a specific vaccine" ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:VO_0001744 a rdfs:Class ;
  rdfs:label "Canine Coronavirus Killed Virus Vaccine (USDA: 14P5.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000932 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0007495 a rdfs:Class ;
  rdfs:label "HLA-A1-binding MAGE-1/MAGE-3 multipeptide-pulsed autologous dendritic cell vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A1-binding melanoma-associated antigen peptides MAGE-1 and MAGE-3 with potential immunomodulating and antineoplastic activity. Upon vaccination, HLA-A1-binding MAGE-1/MAGE-3 multipeptide-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount an anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against MAGE1- and MAGE-3-expressing cancer cells, resulting in tumor cell lysis. HLA-A1 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A1 may improve antigenic peptide immunogenicity." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0016879 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016832 , obo:VO_0016839 .

obo:VO_0010809 a rdfs:Class ;
  rdfs:label "Canine distemper virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0002814 a rdfs:Class ;
  rdfs:label "obsolete B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA" ;
  rdfs:comment "Unmarked rough B. abortus and B. melitensis deletion mutants of manBA (including manA and manB) were attenuated. These mutants provided protection against virulent Brucella challenge in mice" .

obo:VO_0000806 a rdfs:Class ;
  rdfs:label "ineffective" ;
  rdfs:subClassOf obo:VO_0000804 .

obo:VO_0015600 a rdfs:Class ;
  rdfs:label "HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0015555 .

obo:VO_0002346 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Campylobacter Fetus-Leptospira CanicolaGrippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0000568 , obo:VO_0002349 .

obo:VO_0003506 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0003504 .

obo:VO_0016836 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.5 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0016758 .

obo:VO_0011430 a rdfs:Class ;
  rdfs:label "Chlamydophila abortus DNA vaccine encoding MOMP" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001085 .

obo:VO_0003923 a rdfs:Class ;
  rdfs:label "Fluad 2016-2017 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003922 .

obo:VO_0016842 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0016762 .

obo:VO_0016022 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015664 , obo:VO_0015820 .

obo:VO_0002933 a rdfs:Class ;
  rdfs:label "obsolete Shigella sonnei virG/senA/senB/msbB2 mutant vaccine" ;
  rdfs:comment "A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei" .

obo:VO_0003842 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003835 .

obo:NCBITaxon_37124 a rdfs:Class ;
  rdfs:label "Chikungunya virus" ;
  rdfs:subClassOf obo:NCBITaxon_11019 .

obo:VO_0015011 a rdfs:Class ;
  rdfs:label "ActHIB Injectable Product" ;
  rdfs:subClassOf obo:VO_0000004 .

obo:VO_0016667 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10 by Gerke" ;
  rdfs:subClassOf obo:VO_0016626 .

obo:VO_0017915 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injectable Solution [ACWY Vax]" ;
  rdfs:subClassOf obo:VO_0003138 , obo:VO_0017819 .

obo:VO_0010814 a rdfs:Class ;
  rdfs:label "Aeromonas salmonicida protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0020315 a rdfs:Class ;
  rdfs:label "Fluarix 2011-2012 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000045 , obo:VO_0000578 , obo:VO_0010419 .

obo:VO_0019506 a rdfs:Class ;
  rdfs:label "hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0018869 , obo:VO_0019510 .

obo:VO_0017124 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 5 by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0017122 .

obo:VO_0004903 a rdfs:Class ;
  rdfs:label "inactivated monovalent influenza A/H5N1 (3.75 mcg hemagglutinin [HA] A/Indonesia/05/2005) split-virus (SV) vaccine (Sanofi)" ;
  rdfs:comment "Inactivated monovalent influenza A/H5N1 (3.75 mcg hemagglutinin [HA] A/Indonesia/05/2005) split-virus (SV) vaccine (Sanofi)" ;
  rdfs:subClassOf obo:VO_0000065 .

obo:VO_0019181 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0019654 .

obo:VO_0015998 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015660 , obo:VO_0015784 .

obo:VO_0018550 a rdfs:Class ;
  rdfs:label "0.5 ML Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018665 .

obo:VO_0010345 a rdfs:Class ;
  rdfs:label "Fluzone High-Dose Quadrivalent vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000556 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0003478 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010296 , obo:VO_0010415 .

obo:VO_0001618 a rdfs:Class ;
  rdfs:label "Bronchitis Georgia Type, Live Virus Vaccine (USDA: 1231.1L)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0003049 a rdfs:Class ;
  rdfs:label "vaccine conjugate protein" ;
  rdfs:comment "The conjugate protein is a part of a conjugate vaccine and acts as a carrier protein that is covalently attached to a vaccine antigen with poor antigenicity (e.g., a polysaccharide). A conjugate protein is able to induce T-cell-dependent immune responses and stimulate the production of immune memory." ;
  rdfs:subClassOf obo:VO_0000179 .

obo:VO_0015839 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] by Merck" ;
  rdfs:subClassOf obo:VO_0015633 .

obo:VO_0016489 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 10 by Haematogmbh" ;
  rdfs:subClassOf obo:VO_0015978 .

obo:VO_0001120 a rdfs:Class ;
  rdfs:label "Bovilis Neoguard vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000643 , obo:VO_0001065 .

obo:VO_0011040 a rdfs:Class ;
  rdfs:label "UL49 from Bovine herpesvirus 1" ;
  rdfs:comment "Protection against a BHV-1 challenge was obtained in calves immunized with the plasmid encoding tgD-VP22 (UL49), as shown by significant reductions in viral excretion [PubMed: 15650221]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010802 .

obo:VO_0021114 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020344 .

obo:VO_0016569 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Injectable Suspension [Twinrix Paediatric]" ;
  rdfs:subClassOf obo:VO_0016578 .

obo:VO_0019254 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019788 .

obo:VO_0017739 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML [Pediacel]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0017802 .

obo:VO_0012386 a rdfs:Class ;
  rdfs:label "OspC" ;
  rdfs:comment "Mice immunized with recombinant OspC protein were protected from challenge with Borrelia burgdorferi [PubMed: 8168958]." ;
  rdfs:subClassOf obo:VO_0012368 .

obo:VO_0010057 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum Pfs45" ;
  rdfs:comment "A Pfs45 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0002777 a rdfs:Class ;
  rdfs:label "Listeria monocytogenes actA/plcB mutant vaccine" ;
  rdfs:comment "An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes" ;
  rdfs:subClassOf obo:VO_0002500 .

obo:VO_0002610 a rdfs:Class ;
  rdfs:label "siaD from Neisseria meningitidis" ;
  rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001417 .

obo:DOID_0080179 a rdfs:Class ;
  rdfs:label "haemophilus meningitis"@en ;
  rdfs:comment "A bacterial meningitis that has_material_basis_in Haemophilus influenzae infection."@en ;
  rdfs:subClassOf obo:DOID_9470 .

obo:VO_0018189 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus vaccine / Varicella Virus Vaccine Live (Oka-Merck) strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0007300 a rdfs:Class ;
  rdfs:label "Autologous IL-2-expressing B-CLL Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous, B-chronic lymphocytic leukemia (B-CLL) cells harvested from a patient and transduced ex vivo with an adenoviral vector encoding the gene for the human cytokine interleukin-2 (IL-2), with potential immunostimulating and antineoplastic activities. Upon reintroduction into the patient, the autologous IL-2-expressing B-CLL vaccine expresses IL-2, stimulates natural killer (NK) cells, and may enhance the cytotoxic T-lymphocyte (CTL) immune response against the patient's B-CLL cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0002296 a rdfs:Class ;
  rdfs:label "Trichomonas Foetus Vaccine, Killed Protozoa-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4990.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002481 .

obo:VO_0019782 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:IDO_0000420 a rdfs:Class ;
  rdfs:label "biological vector of infectious agent role"@en ;
  rdfs:comment "An infectious agent vector role borne by an organism in virtue of the fact that the infectious agent multiplies in the vector."@en ;
  rdfs:subClassOf obo:IDO_0000418 .

obo:VO_0017025 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017502 .

obo:VO_0020877 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP] Box of 10" ;
  rdfs:subClassOf obo:VO_0020876 , obo:VO_0020884 .

obo:VO_0018923 a rdfs:Class ;
  rdfs:label "influenza A virus A/Sydney/5/2021 (H1N1) antigen" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0004693 a rdfs:Class ;
  rdfs:label "RCN-rabies-G vaccine" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0003100 a rdfs:Class ;
  rdfs:label "Tevax vaccine" ;
  rdfs:comment "An inactIve vaccine used to prevent tetanus." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0010436 .

obo:DOID_65 a rdfs:Class ;
  rdfs:label "connective tissue disease"@en ;
  rdfs:comment "A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage."@en ;
  rdfs:subClassOf obo:DOID_17 .

obo:VO_0011124 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Solomon Islands/3/2006(H1N1))" ;
  rdfs:comment "In mouse models of influenza infection, the vaccines derived from Influenza A virus (A/Solomon Islands/3/2006(H1N1)) hemagglutinin elicit robust antibody responses that mitigate disease and protect mice from lethal challenge [PubMed: 18493310]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:NCBITaxon_2732005 a rdfs:Class ;
  rdfs:label "Bamfordvirae" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:VO_0000295 a rdfs:Class ;
  rdfs:label "human immunodeficiency virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with human immunodeficiency virus that causes AIDS." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0015749 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015497 , obo:VO_0015578 , obo:VO_0015814 .

obo:VO_0002112 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus-Rabies Modified Live & Killed Virus Vaccine (USDA: 13H9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002414 , obo:VO_0007748 .

obo:VO_0018297 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018288 .

obo:VO_0010362 a rdfs:Class ;
  rdfs:label "VAXELIS vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0002836 a rdfs:Class ;
  rdfs:label "E. coli carAB mutant vaccine" ;
  rdfs:comment "A carAB mutant is attenuated in turkeys and induces significant protection from challenge with wild type E. coli" ;
  rdfs:subClassOf obo:VO_0000962 .

obo:VO_0017036 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017032 , obo:VO_0017045 , obo:VO_0017509 .

obo:VO_0019906 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluvirin 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019898 , obo:VO_0020476 .

obo:VO_0003580 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.12 MG/ML [Fluzone 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0015080 .

obo:VO_0004604 a rdfs:Class ;
  rdfs:label "autologous TriMix-DC melanoma vaccine" ;
  rdfs:comment "A dendritic cell vaccine consisting of dendritic cells (DCs) electroporated with mRNA encoding three adjuvants, CD40 ligand (CD40L), a constitutively active TLR4, and CD70 (all together termed TriMix); coelectroporated with full-length mRNA encoding MAGE-A3, MAGE-C2, Tyrosinase and gp100; and linked to DC-LAMP, with potential immunostimulating activity. Upon vaccination, the DCs may stimulate the immune system to mount an antigen-specific cytotoxic T-lymphocyte (CTL) response against the melanoma antigens. This may decrease cellular proliferation of melanoma cells expressing these antigens. Electroporation with the adjuvants CD40L and TLR4 allows for the generation of mature and active DCs; electroporation with CD70 provides a costimulatory signal to CD27+ naive T cells thereby supporting T-cell proliferation and inhibiting T-cell apoptosis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0015261 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0011005 a rdfs:Class ;
  rdfs:label "YapF" ;
  rdfs:comment "Using a mouse model, YPO0606 (yapF) partially protected mice from infection with Y. pestis at a high challenge dosage (200x LD(50)) [PubMed: 19651863]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0016926 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.05 MG/ML Injectable Solution by Aventis" ;
  rdfs:subClassOf obo:VO_0016925 .

obo:VO_0015857 a rdfs:Class ;
  rdfs:label "1 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015610 .

obo:VO_0019381 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000743 , obo:VO_0017799 .

obo:VO_0020938 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.00752 MG/ML" ;
  rdfs:subClassOf obo:VO_0003507 , obo:VO_0004914 .

obo:DOID_229 a rdfs:Class ;
  rdfs:label "female reproductive system disease"@en ;
  rdfs:comment "A reproductive system disease that impairs the ability to reproduce and is located in the uterus, vagina, cervix, ovaries or fallopian tubes."@en ;
  rdfs:subClassOf obo:DOID_15 .

obo:VO_0015217 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015216 , obo:VO_0015307 .

obo:VO_0001963 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4465.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002364 .

obo:VO_0019587 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Flublok 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003894 , obo:VO_0019584 .

obo:VO_0004778 a rdfs:Class ;
  rdfs:label "NYVAC-PRV- gII/ gp50 vaccine" ;
  rdfs:subClassOf obo:VO_0000750 .

obo:VO_0004553 a rdfs:Class ;
  rdfs:label "FMDV DNA vaccine encoding P1 and non-structural proteins 2A, 3C, and 3D" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001213 .

obo:VO_0002520 a rdfs:Class ;
  rdfs:label "obsolete apxIIC from Actinobacillus pleuropneumoniae" ;
  rdfs:comment "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" .

obo:VO_0003901 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003902 .

obo:VO_0001539 a rdfs:Class ;
  rdfs:label "Mink Enteritis vaccine" ;
  rdfs:subClassOf obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001493 , obo:VO_0010475 .

obo:VO_0004772 a rdfs:Class ;
  rdfs:label "NYVAC- CDV-H/F vaccine" ;
  rdfs:subClassOf obo:VO_0012178 .

obo:VO_0020203 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.2 MG/ML" ;
  rdfs:subClassOf obo:VO_0020497 .

obo:VO_0019362 a rdfs:Class ;
  rdfs:label "1 ML hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015279 , obo:VO_0019502 .

obo:VO_0001459 a rdfs:Class ;
  rdfs:label "obsolete Eimeria spp. vaccine" ;
  rdfs:comment "protozoan vaccine that is used to protect against Eimeria spp. (Eimeria) infection" .

obo:VO_0015666 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0015489 .

obo:VO_0018535 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injection [Jespect]" ;
  rdfs:subClassOf obo:VO_0018534 , obo:VO_0018625 .

obo:VO_0006101 a rdfs:Class ;
  rdfs:label "Stable Emulsion (SE) vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant that includes squalene-based oil-in-water emulsion." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0010767 a rdfs:Class ;
  rdfs:label "Human Immunodeficiency Virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0010449 a rdfs:Class ;
  rdfs:label "licensed human rotavirus vaccine" ;
  rdfs:comment "Rotavirus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000658 .

obo:VO_0020064 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Prefilled Syringe [Fluarix 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020314 .

obo:VO_0017545 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Tetamun]" ;
  rdfs:subClassOf obo:VO_0017538 , obo:VO_0017544 .

obo:VO_0003098 a rdfs:Class ;
  rdfs:label "Moraten vaccine" ;
  rdfs:comment "A more attenuated measles vaccine that targets measles virus strain Moraten." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010441 .

obo:VO_0019208 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019712 .

obo:VO_0017958 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.02 MG/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0017927 .

obo:VO_0003083 a rdfs:Class ;
  rdfs:label "influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted by GSK" ;
  rdfs:comment "Product Name: Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0010415 .

obo:VO_0017195 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Prefilled Syringe [Tetanol] Box of 20 by Novartis" ;
  rdfs:subClassOf obo:VO_0017194 .

obo:VO_0018782 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis 0.25 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0001209 a rdfs:Class ;
  rdfs:label "vaccine protection efficacy measurement" ;
  rdfs:comment "vaccine protection efficacy measurement is an assay that measures the protection efficayc of a vaccine." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:NCBITaxon_36470 a rdfs:Class ;
  rdfs:label "Streptococcus sp. 'group A'" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:VO_0001501 a rdfs:Class ;
  rdfs:label "Bovine viral diarrhea virus 1 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Bovine viral diarrhea virus 1 infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003546 .

obo:DOID_9256 a rdfs:Class ;
  rdfs:label "colorectal cancer"@en ;
  rdfs:comment "A large intestine cancer that is located_in the colon and/or located_in the rectum."@en ;
  rdfs:subClassOf obo:DOID_10155 .

obo:VO_0011271 a rdfs:Class ;
  rdfs:label "TcpA" ;
  rdfs:comment "Antibodies against TCP were able to protect baby mice against challenge with V. cholerae O1 of the classical but not of the El Tor biotype [PubMed: 7911787]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010848 .

obo:VO_0015311 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015306 .

obo:VO_0017710 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.016 MG/ML Injectable Suspension [Infanrix] Box of 25 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0017709 .

obo:VO_0002825 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei aroC deletion mutant vaccine" ;
  rdfs:comment "The aroC deletion in the resultant mutant, designated A2 Delta aroC, was confirmed by PCR, Southern hybridization and failure of the mutant to grow in a defined medium without aromatic compounds. The constructed unmarked aroC mutant of B. pseudomallei is attenuated in both BALB/c and C57Bl/6 mice and is able to confer significant protection in C57Bl/6 mice." ;
  rdfs:subClassOf obo:VO_0012175 .

obo:VO_0003934 a rdfs:Class ;
  rdfs:label "GARDASIL Injection" ;
  rdfs:subClassOf obo:VO_0003932 .

obo:VO_0002901 a rdfs:Class ;
  rdfs:label "Salmonella Gallinarum nuoG mutant vaccine" ;
  rdfs:comment "A nuoG mutant is attenuated in chickens and induced significant protection from challenge with wild type S. Gallinarum" ;
  rdfs:subClassOf obo:VO_0002508 .

obo:VO_0010789 a rdfs:Class ;
  rdfs:label "Rotavirus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0004760 a rdfs:Class ;
  rdfs:label "rMVTT-SIV-gpe vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0004325 a rdfs:Class ;
  rdfs:label "PRRSV DNA vaccine GST-ORF5 encoding GP5" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001802 .

obo:OBI_0000652 a rdfs:Class ;
  rdfs:label "material combination" ;
  rdfs:comment "is a material processing with the objective to combine two or more material entities as input into a single material entity as output."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:VO_0007723 a rdfs:Class ;
  rdfs:label "personalized follicular lymphoma vaccine" ;
  rdfs:comment "A cancer vaccine co-administered with poly-ICLC, nivolumab, and rituximab (or another monoclonal antibody against CD20) to treat Follicular Lymphoma. The peptides comprising the vaccine are reconstituted in up to 4 pools with 5 peptides per pool (A, B, C, and D)." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005427 , obo:VO_0007657 .

obo:VO_0017847 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine Injectable Suspension [Meningitec]" ;
  rdfs:subClassOf obo:VO_0010445 , obo:VO_0010724 , obo:VO_0017899 .

obo:VO_0003867 a rdfs:Class ;
  rdfs:label "Hiberix Injectable Product" ;
  rdfs:subClassOf obo:VO_0010715 .

obo:VO_0001003 a rdfs:Class ;
  rdfs:label "pCJ-3 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCJ-3.  This plasmid has a CMV promoter and a kanamycin resistance gene." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0000817 a rdfs:Class ;
  rdfs:label "DNA vaccine expressing multiple HIV epitopes" ;
  rdfs:comment "A HIV vaccine that is composed of a DNA vaccine expressing conserved, multiple HIV epitopes. PMID:16359234." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0003805 a rdfs:Class ;
  rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010307 , obo:VO_0010415 .

obo:VO_0020891 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Fluarix]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0012380 a rdfs:Class ;
  rdfs:label "TbpA" ;
  rdfs:comment "Recombinant TbpA protein was used in a mouse intraperitoneal-infection model to determine their ability to protect against meningococcal infection and to induce cross-reactive and bactericidal antibodies. TbpA was found to afford protection against meningococcal challenge when administered as the sole immunogen [PubMed: 11179327]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010778 .

obo:VO_0021116 a rdfs:Class ;
  rdfs:label "influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020491 .

obo:VO_0001765 a rdfs:Class ;
  rdfs:label "Rabies Live Canarypox Vector Vaccine (USDA: 1901.R1)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000650 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0016109 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015872 .

obo:VO_0002944 a rdfs:Class ;
  rdfs:label "Yersinia pestis smpB/ssrA mutant vaccine" ;
  rdfs:comment "An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0004448 a rdfs:Class ;
  rdfs:label "Prostate cancer DNA vaccine pVax-PSA" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0002531 a rdfs:Class ;
  rdfs:label "fadD26 from Mycobacterium tuberculosis" ;
  rdfs:comment "An fadD26 mutant is attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0019665 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2020 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020490 .

obo:VO_0020955 a rdfs:Class ;
  rdfs:label "influenza B virus antigen 50000000 /ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010301 , obo:VO_0010415 .

obo:VO_0005159 a rdfs:Class ;
  rdfs:label "Ad26.COV2.S vaccine" ;
  rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine composed of Ad26 vector expressing S protein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005268 .

obo:VO_0002368 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Leptospira Hardjo Bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0002358 .

obo:VO_0003528 a rdfs:Class ;
  rdfs:label "influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0003526 .

obo:VO_0007484 a rdfs:Class ;
  rdfs:label "gp100 Protein (184V) vaccine" ;
  rdfs:comment "A recombinant peptide derived from the human melanoma antigen glycoprotein 100 (gp100) with potential use in cancer immunotherapy. gp100 protein(184V) has a valine substitution at position 184. Vaccination with this peptide may evoke a cytotoxic T lymphocyte (CTL) response against tumor cells expression the gp100 antigen." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0015950 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [H B Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015640 , obo:VO_0015724 , obo:VO_0016039 .

obo:VO_0000238 a rdfs:Class ;
  rdfs:label "vaccine dominant epitope" ;
  rdfs:subClassOf obo:VO_0000811 .

obo:VO_0000870 a rdfs:Class ;
  rdfs:label "Babesia bigemina vaccine by local veterinary institutes" ;
  rdfs:subClassOf obo:VO_0001033 .

obo:VO_0010105 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii MIC13" ;
  rdfs:comment "A MIC13 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0002942 a rdfs:Class ;
  rdfs:label "Yersinia pestis nlpD mutant vaccine" ;
  rdfs:comment "An nlpD mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ;
  rdfs:subClassOf obo:VO_0000648 .

obo:VO_0018159 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 40" ;
  rdfs:subClassOf obo:VO_0018143 .

obo:VO_0016453 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Mtk" ;
  rdfs:subClassOf obo:VO_0015974 .

obo:VO_0002235 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live Virus, Live Canarypox Vector Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J9.R1)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002403 , obo:VO_0007748 .

obo:VO_0001751 a rdfs:Class ;
  rdfs:label "Neospora Caninum Killed Protozoa Vaccine (USDA: 1N11.00)" ;
  rdfs:subClassOf obo:VO_0000315 , obo:VO_0000455 , obo:VO_0001065 , obo:VO_0001471 , obo:VO_0007748 .

obo:VO_0003216 a rdfs:Class ;
  rdfs:label "Fluvax vaccine" ;
  rdfs:comment """For the prevention of influenza caused by Influenza Virus, Types A and B. For the Southern
Hemisphere 2017 season, the vaccine is indicated for use only in persons aged 5 years and
over.""" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000642 , obo:VO_0001176 , obo:VO_0010415 .

obo:VO_0017990 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 2000000 CELLS/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 200000 CELLS/ML / poliovirus vaccine inactivated, type 3 (Saukett) 600000 CELLS/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018029 .

obo:VO_0019946 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Flucelvax 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020330 .

obo:VO_0016848 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Boostrix] Box of 25 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016796 .

obo:VO_0017407 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML [Revaxis]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003095 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 , obo:VO_0018793 .

obo:VO_0003669 a rdfs:Class ;
  rdfs:label "YF-Vax Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003665 .

obo:VO_0016558 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0016557 .

obo:VO_0001030 a rdfs:Class ;
  rdfs:label "obsolete vaccine-induced mouse immune response" .

obo:VO_0016775 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension Box of 25" ;
  rdfs:subClassOf obo:VO_0016720 .

obo:DOID_193 a rdfs:Class ;
  rdfs:label "reproductive organ cancer"@en ;
  rdfs:comment "An organ system cancer that is manifested in the reproductive organs."@en ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_15 .

obo:VO_0007365 a rdfs:Class ;
  rdfs:label "CTP-37-DT vaccine" ;
  rdfs:comment "A vaccine composed of synthetic peptides derived from beta-human chorionic gonadotropin (hCG) conjugated to diphtheria toxoid. Vaccination with this peptide may elicit the host immune response against hCG-producing cancer cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0020836 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000662 , obo:VO_0010437 .

obo:VO_0020395 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0020377 , obo:VO_0020399 .

obo:VO_0020198 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.025 MG/ML / SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (BA.4/BA.5) 0.025 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0001298 a rdfs:Class ;
  rdfs:label "interleukin-2 vaccine adjuvant" ;
  rdfs:comment "A cytokine vaccine adjuvant that includes IL-2." ;
  rdfs:subClassOf obo:VO_0001353 .

obo:VO_0004076 a rdfs:Class ;
  rdfs:label "BoNT/F(Hc) vaccine" ;
  rdfs:subClassOf obo:VO_0012187 .

obo:VO_0001710 a rdfs:Class ;
  rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.0A)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0007748 .

obo:VO_0001381 a rdfs:Class ;
  rdfs:label "immunized organism" ;
  rdfs:comment "an organism that is immunized for a disease" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:VO_0016987 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017476 .

obo:VO_0001926 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.24)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002353 .

obo:VO_0000091 a rdfs:Class ;
  rdfs:label "ProQuad vaccine" ;
  rdfs:comment "A Measles-Mumps-Rubella-Vericella vaccine that is live and manufactured by Merck & Co, Inc. " ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000641 , obo:VO_0000737 .

obo:VO_0019349 a rdfs:Class ;
  rdfs:label "0.5 ML Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.008 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML Prefilled Syringe [Prevnar]" ;
  rdfs:subClassOf obo:VO_0000090 , obo:VO_0010210 , obo:VO_0010445 .

obo:VO_0000653 a rdfs:Class ;
  rdfs:label "licensed ferret vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000363 , obo:VO_0001464 .

obo:VO_0004097 a rdfs:Class ;
  rdfs:label "MVA-BN vaccine" ;
  rdfs:subClassOf obo:VO_0000651 .

obo:NCBITaxon_543 a rdfs:Class ;
  rdfs:label "Enterobacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_91347 .

obo:VO_0016240 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [Fendrix] Box of 10 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015909 .

obo:VO_0007473 a rdfs:Class ;
  rdfs:label "indium in 111-labeled autologous polymorphonuclear leukocytes vaccine" ;
  rdfs:comment "A preparation of autologous peripheral polymorphonuclear (PMNLs) radiolabeled with indium In 111 with radioisotopic activity. Autologous PMNLs are isolated, expanded ex vivo, radiolabeled with indium In 111, and then infused back into the patient. Gamma scintigraphy may then be used to image gamma ray-emitting indium In 111 PMNLs localized in lymphoma tissue." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 .

obo:OPL_0000253 a rdfs:Class ;
  rdfs:label "salivary gland-derived sporozoite stage" ;
  rdfs:comment "A sporozoite stage in the Plasmodium lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000152 .

obo:VO_0019493 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.07 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0010437 , obo:VO_0020832 .

obo:VO_0020668 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020749 .

obo:VO_0010193 a rdfs:Class ;
  rdfs:label "influenza, seasonal, Southern Hemisphere, quadrivalent, pediatric 0.25mL dose, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0017556 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017549 , obo:VO_0017555 .

obo:VO_0019834 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003791 .

obo:VO_0017098 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017097 .

obo:VO_0007140 a rdfs:Class ;
  rdfs:label "Sargramostim Plasmid DNA Pancreatic Tumor Cell Vaccine" ;
  rdfs:comment "A whole cell vaccine comprised of irradiated allogenic pancreatic tumor cells transfected with a plasmid DNA encoding human sargramostim (GM-CSF). Vaccination results in expression of GM-CSF, which induces proliferation and differentiation hematopoietic lineage cells as well as stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Furthermore, administration of this pancreatic tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0005430 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0020977 a rdfs:Class ;
  rdfs:label "Influenza Virus Fragmented, Inactivated, Strain B / Phuket / 3073/2013 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0020973 .

obo:VO_0015532 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution [Fendrix]" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0000178 a rdfs:Class ;
  rdfs:label "inactivated vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a inactivated vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0010074 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi rTcENO from H8" ;
  rdfs:comment "A rTcENO from H8 protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0004720 a rdfs:Class ;
  rdfs:label "rVCG- Chlamydia-cholera vaccine" ;
  rdfs:subClassOf obo:VO_0001207 .

obo:VO_0019401 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 600 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003196 .

obo:VO_0010803 a rdfs:Class ;
  rdfs:label "West Nile virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0016042 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 25" ;
  rdfs:subClassOf obo:VO_0015669 , obo:VO_0015797 .

obo:VO_0004043 a rdfs:Class ;
  rdfs:label "Rotavirus VP6 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000658 .

obo:VO_0001206 a rdfs:Class ;
  rdfs:label "vaccine protection efficacy datum" ;
  rdfs:comment "A measurement datum that represents a type of vaccine protection efficacy as an outcome of a vaccine protection study. The result can be represented as a digit, for example, 0 = no protection, and 1 = protection (determined by a p-value cutoff)." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0000578 a rdfs:Class ;
  rdfs:label "H1N1 influenza vaccine" ;
  rdfs:comment "H1N1 Influenza vaccine is an Influenza virus vaccine that is used to vaccinate against H1N1 Influenza subtype vaccine." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000642 .

obo:VO_0015907 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 50" ;
  rdfs:subClassOf obo:VO_0003267 .

obo:VO_0002432 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Chlamydia Psittaci vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000563 , obo:VO_0000573 , obo:VO_0000843 , obo:VO_0001465 .

obo:VO_0016930 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 2 LFU/ML / tetanus toxoid vaccine, inactivated 2 LFU/ML Injection Box of 10" ;
  rdfs:subClassOf obo:VO_0016929 , obo:VO_0017392 .

obo:VO_0003046 a rdfs:Class ;
  rdfs:label "Schistosoma mansoni vaccine" ;
  rdfs:comment "A protozoan vaccine against Schistosoma mansoni" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003047 .

obo:VO_0015572 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015492 , obo:VO_0015531 .

obo:VO_0001966 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4466.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002364 .

obo:VO_0010283 a rdfs:Class ;
  rdfs:label "vaccine vector datum" ;
  rdfs:comment "A measurment datum that records the vaccine vector of a vaccine." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:VO_0017117 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension Box of 2" ;
  rdfs:subClassOf obo:VO_0017073 , obo:VO_0017577 .

obo:VO_0010330 a rdfs:Class ;
  rdfs:label "intratumoral route" ;
  rdfs:comment "A route of administration that inject the material (such as vaccines, allergens) directly into a tumor." ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0010778 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0010852 a rdfs:Class ;
  rdfs:label "Entamoeba histolytica protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0000227 a rdfs:Class ;
  rdfs:label "reaction to previous vaccination" ;
  rdfs:subClassOf obo:VO_0000207 .

obo:VO_0001814 a rdfs:Class ;
  rdfs:label "West Nile Virus Live Canarypox Vector Vaccine (USDA: 1991.R0)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000752 , obo:VO_0001220 , obo:VO_0001475 , obo:VO_0007748 .

obo:VO_0016685 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Pediacel]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0017947 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.05 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Menjugate]" ;
  rdfs:subClassOf obo:VO_0017908 .

obo:VO_0021154 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 0.05 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010444 .

obo:VO_0005152 a rdfs:Class ;
  rdfs:label "MVA-MERS-S vaccine" ;
  rdfs:comment "A MERS recombinant vector made of recombinant modified vaccinia virus Ankara (rMVA) vaccine vector carrying full MERS-CoV spike glycoprotein." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0004900 .

obo:VO_0010183 a rdfs:Class ;
  rdfs:label "influenza, split virus, quadrivalent, injectable, preservative free" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0001937 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4509.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002488 .

obo:VO_0016582 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Twinrix Paediatric]" ;
  rdfs:subClassOf obo:VO_0016569 , obo:VO_0016585 .

obo:VO_0007701 a rdfs:Class ;
  rdfs:label "multiantigen liposome loaded dendritic cell vaccine" ;
  rdfs:comment "A cancer vaccine for which Advanced Renal Cell Carcinoma patients undergo total nephrectomy to harvest primary tumor for vaccine preparation. Dendritic cells are then pulsed with multiantigens or tumor cells. Some patients also receive vaccination with irradiated autologous tumor lysate. The vaccine may make the body build an immune response to kill tumor cells." ;
  rdfs:subClassOf obo:VO_0005494 , obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0004843 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0004839 .

obo:VO_0016774 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0016720 .

obo:VO_0016519 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Europharma" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0018044 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003837 .

obo:VO_0007071 a rdfs:Class ;
  rdfs:label "URLC10-CDCA1-KOC1 Multipeptide Vaccine" ;
  rdfs:comment "A cancer vaccine containing multiple peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this vaccine are derived from, URLC10 (up-regulated lung cancer 10), CDCA1 (cell division cycle-associated protein 1), KOC1 (IGF II mRNA Binding Protein 3). Upon administration, URLC10-CDCA1-KOC1 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, CDCA1, KCO1 peptides, resulting in cell lysis and decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005490 , obo:VO_0007657 .

obo:VO_0018725 a rdfs:Class ;
  rdfs:label "Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injection [Typherix]" ;
  rdfs:subClassOf obo:VO_0018718 , obo:VO_0018724 .

obo:VO_0019474 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.015 MG/ML / Neisseria meningitidis 0.25 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0019468 .

obo:VO_0017616 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetanol]" ;
  rdfs:subClassOf obo:VO_0017592 , obo:VO_0017610 .

obo:VO_0018592 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.00752 MG/ML" ;
  rdfs:subClassOf obo:VO_0018768 .

obo:VO_0018261 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injectable Solution [Rabipur]" ;
  rdfs:subClassOf obo:VO_0018270 .

obo:VO_0003579 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2013-2014 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0004914 , obo:VO_0010416 .

obo:VO_0002111 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus-Rabies Modified Live & Killed Virus Vaccine (USDA: 13G9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002466 , obo:VO_0007748 .

obo:VO_0000167 a rdfs:Class ;
  rdfs:label "pcDNA3.1V5HisTOPO/TA DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0007139 a rdfs:Class ;
  rdfs:label "rF-MUC1(DF3)/TRICOM Vaccine" ;
  rdfs:comment "A fowlpox vaccine containing the tumor-associated antigen mucin-1 (MUC1), found in pancreatic tumor cells, and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; TRICOM), which is designed to enhance antigen presentation and activation of immune responses critical for tumor destruction. Vaccination with this agent may elicit a host immune response against MUC1-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005430 , obo:VO_0007657 .

obo:VO_0020750 a rdfs:Class ;
  rdfs:label "BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension [Bcg Medac]" ;
  rdfs:subClassOf obo:VO_0020748 , obo:VO_0020749 , obo:VO_0020756 .

obo:NCBITaxon_314293 a rdfs:Class ;
  rdfs:label "Simiiformes" ;
  rdfs:subClassOf obo:NCBITaxon_9443 .

obo:VO_0003264 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0003258 .

obo:VO_0005434 a rdfs:Class ;
  rdfs:label "PVSRIPO vaccine vector" ;
  rdfs:comment "A recombinant viral vaccine vector that uses PVSRIPO, a recombinant nonpathogenic polio-rhinovirus chimera. PVSRIPO is an engineerable oncolytic virus whereas its internal ribosomal entry site element can be substituted to demolish its cytopathogenic effect. PVSRIPO has a natural inherent tropism for antigen-presenting cells (including dendritic cells and macrophages) due to the presence of the CD-155 receptor on their cellular surfaces. This enables it of inducing CD8+ T-cell mediate immune responses." ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0001790 a rdfs:Class ;
  rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.01)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001456 , obo:VO_0007748 .

obo:VO_0004287 a rdfs:Class ;
  rdfs:label "M2 mutant from influenza A vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0002132 a rdfs:Class ;
  rdfs:label "Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.27)" ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002421 , obo:VO_0007748 .

obo:VO_0017656 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Repevax]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:NCBITaxon_9625 a rdfs:Class ;
  rdfs:label "Vulpes" ;
  rdfs:subClassOf obo:NCBITaxon_9608 .

obo:VO_0007123 a rdfs:Class ;
  rdfs:label "Xenogeneic Tyrosinase DNA vaccine" ;
  rdfs:comment "A plasmid DNA vaccine, encoding an epitope of mouse tyrosinase, with potential antineoplastic activity. Administered via intramuscular electroporation, vaccination with xenogeneic tyrosinase DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) immune responses against melanoma cells that express tyrosinase, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0016800 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Repevax] Box of 10" ;
  rdfs:subClassOf obo:VO_0016725 , obo:VO_0016742 , obo:VO_0016819 .

obo:VO_0018587 a rdfs:Class ;
  rdfs:label "1.5 ML Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 667000 /ML Oral Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018583 , obo:VO_0018690 .

obo:VO_0020483 a rdfs:Class ;
  rdfs:label "Fluzone 2019-2020 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 , obo:VO_0010420 .

obo:VO_0019699 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2015-2016]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003616 , obo:VO_0010427 .

obo:VO_0020823 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0017567 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Revaxis]" ;
  rdfs:subClassOf obo:VO_0017552 , obo:VO_0017555 .

obo:VO_0015169 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015164 .

obo:VO_0019651 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020489 .

obo:VO_0007623 a rdfs:Class ;
  rdfs:label "Incomplete Freund's adjuvant (IFA) alone, or a melanoma vaccine in IFA" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0001941 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002358 .

obo:VO_0016420 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015967 .

obo:VO_0002681 a rdfs:Class ;
  rdfs:label "obsolete senB from Shigella" ;
  rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" .

obo:VO_0002711 a rdfs:Class ;
  rdfs:label "3a from Feline infectious peritonitis virus" ;
  rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001434 .

obo:VO_0000542 a rdfs:Class ;
  rdfs:label "equine EEV, VEV and WEV encephalomyelitis-rhinopneumonitis-influenza vaccine-tetanus toxoid" ;
  rdfs:subClassOf obo:VO_0000541 , obo:VO_0002428 .

obo:VO_0002542 a rdfs:Class ;
  rdfs:label "RD1 from Mycobacterium tuberculosis" ;
  rdfs:comment "RD1 and panCD mutants in Mycobacterium tuberculosis were attenuated and provided protection in CD4-deficient mice against an aerosol challenge with virulent M. tuberculosis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0002026 a rdfs:Class ;
  rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4595.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002380 .

obo:VO_0003027 a rdfs:Class ;
  rdfs:label "human serum albumin vaccine additive" ;
  rdfs:comment "a protein vaccine stablizer that is specifically human serum albumin." ;
  rdfs:subClassOf obo:VO_0003038 .

obo:VO_0001453 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii gene" ;
  rdfs:comment "A protozoan gene that is from Toxoplasma gondii." ;
  rdfs:subClassOf obo:VO_0000170 .

obo:VO_0021095 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2022-2023 Northern Hemisphere vaccine Injection" ;
  rdfs:subClassOf obo:VO_0003073 , obo:VO_0010428 .

obo:VO_0010258 a rdfs:Class ;
  rdfs:label "vaccine vector variable" ;
  rdfs:comment "A variable representing the vaccine vector (DNA plasmid, viral vector) etc." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0004136 a rdfs:Class ;
  rdfs:label "VSV-based vaccine expressing MBGV GP" ;
  rdfs:subClassOf obo:VO_0012163 .

obo:VO_0002201 a rdfs:Class ;
  rdfs:label "Fowl Pox-Mycoplasma Gallisepticum Live Fowl Pox Vector Vaccine (USDA: 1D51.R0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002445 , obo:VO_0007748 .

obo:VO_0010793 a rdfs:Class ;
  rdfs:label "Tick-borne Encephalitis Virus (TBEV) protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0003249 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 33F vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:VO_0001260 a rdfs:Class ;
  rdfs:label "Titermax Gold vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant which is a water-in-oil adjuvant with CRL-8300 (a block copolymer), squalene, and sorbitan monooleate." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0004437 a rdfs:Class ;
  rdfs:label "Lung metastasis DNA vaccine pCEP4-MUC1 encoding MUC1" ;
  rdfs:comment "Gene name: MUC1" ;
  rdfs:subClassOf obo:VO_0005486 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0010994 a rdfs:Class ;
  rdfs:label "IpaB" ;
  rdfs:comment "The invasiveness and virulence of Shigella spp. are largely due to the expression of plasmid-encoded virulence factors, among which are the invasion plasmid antigens (IpaB, IpaC, and IpaD). Recent observations have indicated that the Ipa proteins (IpaB, IpaC, and possibly IpaD) form a multiprotein complex capable of inducing the phagocytic event which internalizes the bacterium.  Researchers isolated a complex of invasins and LPS from water-extractable antigens of virulent shigellae.  Western blot analysis of the complex indicates that all of the major virulence antigens of Shigella, including IpaB, IpaC, and IpaD, and LPS are components of this macromolecular complex.  Guinea pigs (keratoconjunctivitis model) or mice (lethal lung model) immunized intranasally with purivied invasin complex (invaplex) on days 0, 14, and 28 and challenged 3 weeks later with virulent shigellae were protected from disease (P<0.01 for both animal models) [PubMed: 11083774]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010777 .

obo:VO_0002599 a rdfs:Class ;
  rdfs:label "purC/purD from Francisella tularensis" ;
  rdfs:comment "A purMCD mutant in Francisela tularensis was attenuated. A low dosage of F. tularensis LVS delta purMCD mutant provided protection against challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001414 .

obo:VO_0018801 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003948 , obo:VO_0018617 .

obo:VO_0018229 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Prefilled Syringe [Priorix]" ;
  rdfs:subClassOf obo:VO_0018227 , obo:VO_0018228 .

obo:VO_0020041 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003499 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0004790 a rdfs:Class ;
  rdfs:label "rBCG-S2PT vaccine" ;
  rdfs:subClassOf obo:VO_0000765 .

obo:VO_0015761 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015582 , obo:VO_0015817 .

obo:VO_0003774 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2018-2019 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003773 .

obo:VO_0020086 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain 158000000 UNT/ML Nasal Spray [Flumist 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020084 , obo:VO_0020348 .

obo:VO_0010158 a rdfs:Class ;
  rdfs:label "diphtheria and tetanus toxoids, adsorbed for pediatric use" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000732 , obo:VO_0010436 , obo:VO_0010445 .

obo:VO_0020787 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 ORGANISMS Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0020782 .

obo:VO_0011423 a rdfs:Class ;
  rdfs:label "Herpes simplex virus type 1 DNA vaccine encoding GE" ;
  rdfs:comment "An HSV-1 gE (Us8) deletion strain, NS-gEnull, was used as a live attenuated vaccine. After HSV-1 challenge, latent virus was recovered by DRG explant cocultures from <10% of vaccinated mice compared with 100% of mock-vaccinated mice" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000958 .

obo:VO_0003539 a rdfs:Class ;
  rdfs:label "Orthopoxvirus vaccine" ;
  rdfs:comment "A vaccine that is used against an infection by a pathogen under Orthopoxvirus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000512 .

obo:VO_0001847 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002434 , obo:VO_0007748 .

obo:VO_0017937 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group B vaccine 0.3 MG/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017903 .

obo:VO_0007519 a rdfs:Class ;
  rdfs:label "dendritic vaccine, allogeneic hematopoietic stem cells, cytotoxic lymphocytes" ;
  rdfs:comment "A cancer vaccine made of tumor cells and tumor stem cells that are isolated from a sample from a patient with glioblastoma multiforme. Dendritic cells are isolated from peripheral blood mononuclear cells and cultured. The tumor sample provides tumor specific antigens to prepare the dendritic vaccine. Cytotoxic lymphocytes are obtained from peripheral blood after dendritic vaccine administrations. Hematopoietic stem cells are harvested from closely related donor after granulocyte-colony-stimulating factor (G-CSF) administration. Allogeneic haploidentical hematopoietic stem cells are administered intrathecally, dendritic cells are administered subcutaneously, and cytotoxic lymphocytes are adminstered intrathecally. The combination of these treatments may control tumor cell quantity and target regulation of effector functions of tumor stem cells." ;
  rdfs:subClassOf obo:VO_0005428 , obo:VO_0007657 , obo:VO_0007658 .

obo:NCBITaxon_1649845 a rdfs:Class ;
  rdfs:label "Yersinia pseudotuberculosis complex" ;
  rdfs:subClassOf obo:NCBITaxon_629 .

obo:VO_0004017 a rdfs:Class ;
  rdfs:label "influenza virus HA protein vaccine (influenza A virus (A/Yamagata/120/1986(H1N1)))" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0007198 a rdfs:Class ;
  rdfs:label "Adenovector-transduced AP1903-inducible MyD88/CD40-expressing Autologous PSMA-specific Prostate Cancer Vaccine BPX-201" ;
  rdfs:comment "A genetically-modified, dendritic cell-based (DCs) vaccine in which the autologous cells are transduced with an adenoviral vector expressing the tumor antigen prostate-specific membrane antigen (PSMA) and a fusion protein composed of synthetic ligand inducible adjuvant iMC composed of a drug-inducible costimulatory CD40 receptor (iCD40) and the adaptor protein MyD88, with potential immunomodulating and antineoplastic activities. The iCD40 contains a membrane-localized cytoplasmic CD40 domain fused to the FK506 modified drug-binding protein 12 (FKBP12). Upon intradermal administration of BPX-201, these DCs accumulate in local draining lymph nodes. Twenty-four hours after vaccination, the dimerizing agent AP1903 is administered. AP1903 binds to the drug binding domain, leading to iMC oligomerization and activation of iCD40 and MyD88-mediated signaling in iMC-expressing DCs. This signaling pathway activates the DCs and stimulates a cytotoxic T-lymphocyte (CTL) response against host tumor cells that express PSMA. PSMA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed in prostate cancer cells and is used as a tumor marker for both diagnosis and treatment evaluation. MyD88 is involved in interleukin 1 receptor (IL1R) and toll-like receptor (TLR) signaling." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0010460 a rdfs:Class ;
  rdfs:label "SARS Coronavirus 2 XBB.1.5" ;
  rdfs:subClassOf obo:NCBITaxon_2697049 .

obo:VO_0016388 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites] Box of 3 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015949 .

obo:VO_0004612 a rdfs:Class ;
  rdfs:label "Newcastle disease virus lysate vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0004506 a rdfs:Class ;
  rdfs:label "PRRSV DNA vaccine pCA-U-optiGP5" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001802 .

obo:VO_0005492 a rdfs:Class ;
  rdfs:label "myeloma cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is developed against myeloma cancer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0012391 a rdfs:Class ;
  rdfs:label "MecA" ;
  rdfs:comment "An internal region from the transpeptidase domain from the PBP2a (encoded by mecA) was cloned into a mammalian expression vector, to be used as DNA vaccine in a Murine model. After three sets of DNA vaccination, the immune response represented by antibodies against a fragment of PBP2a was evaluated by enzyme linked immunosorbent assay (ELISA), showing a significant antibody response. The antibacterial effect of the DNA vaccine was evaluated by intraperitoneal immunization and challenge with a sublethal dose of MRSA for 7 days in mice. After the challenge, the number of bacteria from kidneys from immunized and non-immunized mice were determined. Kidneys from immunized mice had 1000 times less on bacteria than the positive controls (non-immunized mice) [PubMed: 12744903]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012355 .

obo:VO_0019728 a rdfs:Class ;
  rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0018362 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.002 MG" ;
  rdfs:subClassOf obo:VO_0003342 .

obo:VO_0001930 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002353 .

obo:VO_0001438 a rdfs:Class ;
  rdfs:label "Human metapneumovirus gene" ;
  rdfs:comment "A viral gene that is from Human metapneumovirus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0002449 a rdfs:Class ;
  rdfs:label "Mink Distemper-Enteritis Vaccine-Clostridium Botulinum Type C Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0002451 , obo:VO_0002484 .

obo:VO_0016216 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0015904 .

obo:VO_0004070 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae PiaA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0015164 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0015149 , obo:VO_0015175 , obo:VO_0015240 .

obo:VO_0020211 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0020498 .

obo:VO_0001217 a rdfs:Class ;
  rdfs:label "live attenuated bacterial vaccine" ;
  rdfs:comment "Bacterial vaccine that is live and attenuated." ;
  rdfs:subClassOf obo:VO_0000165 , obo:VO_0000367 .

obo:VO_0001133 a rdfs:Class ;
  rdfs:label "assay of CFU reduction in lung" ;
  rdfs:comment "assay of CFU reduction in lung is a CFU reduction assay that is measured using the extracted lung as the tissue for isolation of infected pathogens." ;
  rdfs:subClassOf obo:VO_0000242 .

obo:VO_0017782 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 20" ;
  rdfs:subClassOf obo:VO_0017780 , obo:VO_0017786 .

obo:VO_0019417 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.0468 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.0468 MG/ML / diphtheria toxoid vaccine, inactivated 13.4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension [Tripedia]" ;
  rdfs:subClassOf obo:VO_0000112 , obo:VO_0000561 , obo:VO_0001214 , obo:VO_0017799 .

obo:VO_0020614 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML Injection [Varivax] by Sanofi" ;
  rdfs:subClassOf obo:VO_0015029 .

obo:VO_0015633 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015567 , obo:VO_0015668 .

obo:VO_0015561 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.001 MG/ML Prefilled Syringe [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015502 , obo:VO_0015593 .

obo:VO_0007235 a rdfs:Class ;
  rdfs:label "Alpha Fetoprotein Adenoviral Vector Vaccine" ;
  rdfs:comment "A vaccine consisting of a recombinant adenoviral vector encoding alpha fetoprotein. After vaccination, expressed alpha fetoprotein may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells that express alpha fetoprotein, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005429 , obo:VO_0007657 .

obo:VO_0015626 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix]" ;
  rdfs:subClassOf obo:VO_0015583 , obo:VO_0015664 .

obo:VO_0007006 a rdfs:Class ;
  rdfs:label "Synthetic Glioblastoma Mutated Tumor-specific Peptides Vaccine Therapy APVAC2" ;
  rdfs:comment "A personalized peptide-based cancer vaccine comprised of one or two de novo synthesized patient-specific tumor-mutated peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB mutated tumor-specific peptides vaccine therapy APVAC2 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the selected mutated tumor-associated peptides, which results in decreased GB growth. These peptides are specifically selected and synthesized based on the expression of the patient‚Äö√†√∂‚àö√òs own mutated tumor-associated antigens, which were detected during individual tumor genome sequencing." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005428 , obo:VO_0007657 .

obo:NCBITaxon_624 a rdfs:Class ;
  rdfs:label "Shigella sonnei" ;
  rdfs:subClassOf obo:NCBITaxon_620 .

obo:VO_0002621 a rdfs:Class ;
  rdfs:label "clpP from Salmonella Enteritidis" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective, and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001422 .

obo:VO_0000568 a rdfs:Class ;
  rdfs:label "Campylobacter vaccine" ;
  rdfs:comment "A vaccine that protects against Campylobacter bacterial infectioni." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0020097 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001178 , obo:VO_0003501 , obo:VO_0010415 .

obo:OPL_0000294 a rdfs:Class ;
  rdfs:label "Plasmodium hepatic merozoite stage" ;
  rdfs:comment "A hepatic merozoite stage in the Plasmodium lifecycle that occurs in the hepatocyte of a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000247 , obo:OPL_0000292 .

obo:VO_0001322 a rdfs:Class ;
  rdfs:label "E. coli heat-labile toxin vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant containing E. coli heat-labile toxin." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0011553 a rdfs:Class ;
  rdfs:label "Rabies DNA vaccine encoding Rabies virus Glycoprotein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000650 .

obo:DOID_848 a rdfs:Class ;
  rdfs:label "arthritis"@en ;
  rdfs:comment "A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located_in joint."@en ;
  rdfs:subClassOf obo:DOID_0080001 .

obo:NCBITaxon_10345 a rdfs:Class ;
  rdfs:label "Suid alphaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_10319 .

obo:VO_0015521 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Intramuscular Solution [Recombivax]" ;
  rdfs:subClassOf obo:VO_0015525 .

obo:VO_0019654 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0015145 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine, Inactivated 320 UNT/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0015331 .

obo:VO_0001990 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002362 .

obo:VO_0019550 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0003745 , obo:VO_0019544 .

obo:VO_0010841 a rdfs:Class ;
  rdfs:label "Western equine encephalomyelitis virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0000150 a rdfs:Class ;
  rdfs:label "antibody titer" ;
  rdfs:comment "A titer of antibody that shows how much antibody an organism has produced that recognizes a particular epitope, expressed as the greatest dilution ratio (or its reciprocal) that still gives a positive result. ELISA is a common means of determining antibody titers." ;
  rdfs:subClassOf obo:VO_0000555 .

obo:VO_0002206 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4629.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002397 , obo:VO_0007748 .

obo:VO_0002871 a rdfs:Class ;
  rdfs:label "Salmonella Enteritidis guaBA/clpP mutant vaccine" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective, and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis" ;
  rdfs:subClassOf obo:VO_0002509 .

obo:VO_0003629 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2016-2017]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003627 .

obo:VO_0018651 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0003303 .

obo:VO_0017154 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Infanrix] Box of 25" ;
  rdfs:subClassOf obo:VO_0017153 , obo:VO_0017186 , obo:VO_0017612 .

obo:VO_0020874 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Preflucel]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020899 .

obo:VO_0001078 a rdfs:Class ;
  rdfs:label "recombinant heterologous vector vaccine" ;
  rdfs:comment "a recombinant vector vaccine that uses a homologous vector, i.e., when the target species of the vaccine is not one of the natural hosts for the vector." ;
  rdfs:subClassOf obo:VO_0000484 .

obo:VO_0015045 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 52 Vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003307 .

obo:VO_0017648 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution [Tetanol]" ;
  rdfs:subClassOf obo:VO_0003397 .

obo:VO_0018033 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018046 .

obo:VO_0000031 a rdfs:Class ;
  rdfs:label "MenHibrix vaccine" ;
  rdfs:comment "A vaccine for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroups C and Y and Haemophilus influenzae type b. MENHIBRIX is approved for use in children 6 weeks of age through 18 months of age." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0000641 , obo:VO_0000662 , obo:VO_0001214 , obo:VO_0010290 , obo:VO_0010437 , obo:VO_0010444 .

obo:OBI_0000319 a rdfs:Class ;
  rdfs:label "material to be added role"@en ;
  rdfs:comment "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role is added into another material entity (the target)."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:VO_0017904 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec]" ;
  rdfs:subClassOf obo:VO_0017847 .

obo:VO_0012378 a rdfs:Class ;
  rdfs:label "HspB from Helicobacter pylori" ;
  rdfs:comment "Orogastric immunization of mice with recombinant H. pylori HspB proteins protected 70% of animals from a challenge dose of 10^4 Helicobacter felis bacteria [PubMed: 7604021]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010855 .

obo:VO_0007058 a rdfs:Class ;
  rdfs:label "WT1 235-243 peptide vaccine" ;
  rdfs:comment "A synthetic peptide vaccine consisting of a HLA-A24-restricted human Wilms' Tumor protein-1 (WT1) peptide comprised of amino acids 235 through 243, a MHC class I-restricted peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 235-243 peptide may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0020905 a rdfs:Class ;
  rdfs:label "Influenza A virus / Influenza B virus Injectable Suspension [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020903 .

obo:VO_0016674 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML [Revaxis]" ;
  rdfs:subClassOf obo:VO_0003429 .

obo:VO_0018198 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0010735 , obo:VO_0018197 .

obo:VO_0001860 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D8.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0002436 , obo:VO_0007748 .

obo:VO_0019847 a rdfs:Class ;
  rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010431 .

obo:VO_0003267 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B]" ;
  rdfs:subClassOf obo:VO_0003258 .

obo:VO_0001849 a rdfs:Class ;
  rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live & Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.2C)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0002434 , obo:VO_0007748 .

obo:VO_0019284 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Flulaval Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020342 .

obo:VO_0002534 a rdfs:Class ;
  rdfs:label "mce-2 from Mycobacterium tuberculosis" ;
  rdfs:comment "A Mce-2 mutant in Mycobacterium tuberculosis is attenuated and provides protection against challenge for mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000164 .

obo:VO_0001267 a rdfs:Class ;
  rdfs:label "saponin vaccine adjuvant" ;
  rdfs:comment "A tensoactive compound vaccine adjuvant that is derived from saponin, a compound that is an immunostimulator found in the plant P. senega." ;
  rdfs:subClassOf obo:VO_0001358 .

obo:DOID_0040084 a rdfs:Class ;
  rdfs:label "Streptococcus pneumonia"@en ;
  rdfs:comment "A bacterial pneumonia has_material_basis_in Streptococcus pneumoniae."@en ;
  rdfs:subClassOf obo:DOID_874 .

obo:VO_0003734 a rdfs:Class ;
  rdfs:label "Afluria 2018-2019 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003733 .

obo:VO_0003853 a rdfs:Class ;
  rdfs:label "Typhim VI Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003850 .

obo:VO_0002015 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4367.30)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002373 .

obo:VO_0010064 a rdfs:Class ;
  rdfs:label "Plasmodium vivax PvDBPII" ;
  rdfs:comment "A DBPII protein that is part of Plasmodium vivax|A PvDBPII protein that is part of Plasmodium vivax" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015473 .

obo:VO_0003568 a rdfs:Class ;
  rdfs:label "PNEUMOVAX 23 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003567 .

obo:NCBITaxon_1502 a rdfs:Class ;
  rdfs:label "Clostridium perfringens" ;
  rdfs:subClassOf obo:NCBITaxon_1485 .

obo:VO_0002298 a rdfs:Class ;
  rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae Bacterin (USDA: 4993.21)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0001214 , obo:VO_0002478 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0018576 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018570 , obo:VO_0018765 .

obo:VO_0000325 a rdfs:Class ;
  rdfs:label "Brucella melitensis DNA vaccine encoding Omp31" ;
  rdfs:subClassOf obo:VO_0001226 .

obo:VO_0020902 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Xanaflu]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0017844 a rdfs:Class ;
  rdfs:label "meningococcal group B vaccine Injectable Suspension [Bexsero]" ;
  rdfs:subClassOf obo:VO_0003066 , obo:VO_0017895 .

obo:VO_0002159 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1762.1H)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0002949 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 UL23 mutant vaccine" ;
  rdfs:comment "A thymidine kinase-deficient mutant (B8-D53) showed no detectable thymidine kinase-inducing activity and was attenuated in calves. B8-D53 also induced protection from challenge with wild type BHV-1" ;
  rdfs:subClassOf obo:VO_0000987 .

obo:VO_0010296 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003498 , obo:VO_0010297 .

obo:VO_0020122 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide / meningococcal group C polysaccharide / meningococcal polysaccharide vaccine group W-135 / meningococcal polysaccharide vaccine group Y Injectable Solution [Menomune A/C/Y/W-135]" ;
  rdfs:subClassOf obo:VO_0000072 , obo:VO_0017819 , obo:VO_0020131 .

obo:VO_0000344 a rdfs:Class ;
  rdfs:label "intraperitoneal route" ;
  rdfs:comment "A route of administration that located in the peritoneum." ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0011513 a rdfs:Class ;
  rdfs:label "Helicobacter pylori catalase protein vaccine" ;
  rdfs:subClassOf obo:VO_0012181 .

obo:VO_0003140 a rdfs:Class ;
  rdfs:label "non-small cell lung cancer vaccine" ;
  rdfs:comment "A cancer vaccine against non-small cell lung cancer (NSCLC)" ;
  rdfs:subClassOf obo:VO_0000177 , obo:VO_0005486 .

obo:VO_0005376 a rdfs:Class ;
  rdfs:label "Th1/Th2/Th17 mixed immune profile" ;
  rdfs:comment "An immune profile that is characterized by the presense of Type 1 Type 2, and Th17 T helper cells." ;
  rdfs:subClassOf obo:VO_0005308 .

obo:VO_0004585 a rdfs:Class ;
  rdfs:label "Infectious Bursal Disease virus DNA vaccine expressing VP2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001497 .

obo:VO_0015491 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0003275 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0018218 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 1000 UNT / Mumps virus 25100 UNT / Rubella virus vaccine 1000 UNT / Varicella Virus Vaccine Live (Oka-Merck) strain 1000 UNT Injectable Solution [Priorix-Tetra]" ;
  rdfs:subClassOf obo:VO_0018216 , obo:VO_0018217 .

obo:VO_0002032 a rdfs:Class ;
  rdfs:label "avian influenza-Fowl Pox H5 Subtype, Live Fowl Pox Vector Vaccine (USDA: 1061.R0)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000657 , obo:VO_0001178 , obo:VO_0002329 , obo:VO_0003143 , obo:VO_0007748 .

obo:VO_0002336 a rdfs:Class ;
  rdfs:label "bovine rhinotracheitis vaccine-leptospira pomona bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0000987 .

obo:VO_0002198 a rdfs:Class ;
  rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 1A88.R1)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002382 , obo:VO_0007748 .

obo:VO_0010474 a rdfs:Class ;
  rdfs:label "mechanistic correlate of immune protection" ;
  rdfs:comment "Correlated profile of immune protection that is mechanistically and causally responsible for protection." ;
  rdfs:subClassOf obo:VO_0010472 .

obo:VO_0011529 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine encoding NP from influenza A virus (A/chicken/Hubei/489/2004(H5N1))" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0020866 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippeimpfstoff Ratiopharm] Box of 10" ;
  rdfs:subClassOf obo:VO_0020865 , obo:VO_0020884 .

obo:VO_0010420 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2019-2020" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0019864 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0015530 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Solution [Bimmugen]" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0003318 a rdfs:Class ;
  rdfs:label "TDAP/IPV vaccine foreign to USA" ;
  rdfs:comment "A vaccine against tetanus, diphtheria, pertussis, and inactivated poliovirus manufactured outside of the U.S." ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0003180 , obo:VO_0003444 , obo:VO_0010447 .

obo:VO_0000637 a rdfs:Class ;
  rdfs:label "Flavobacterium columnare vaccine" ;
  rdfs:comment "bacterial vaccine that is used to protect against Flavobacterium columnare infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0016831 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016759 .

obo:VO_0003551 a rdfs:Class ;
  rdfs:label "Enterobacterales vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0007670 a rdfs:Class ;
  rdfs:label "HER2 ICD peptide vaccine" ;
  rdfs:comment "A cancer vaccine made from peptides that may help the body build an effective immune response to kill tumor cells. Patients with HER2 positive locally advanced breast cancer can be vaccinated with a HER2 Intracellular Domain (ICD) peptide-based vaccine administered concurrently with trastuzumab. The vaccine may lead to an immune response (HER2 specific T cell immunity and/or the development of intramolecular epitope spreading)." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0002788 a rdfs:Class ;
  rdfs:label "Streptococcus suis vaccine" ;
  rdfs:comment "a bacterial vaccine against Streptococcus suis infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000772 .

obo:VO_0018428 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0018517 .

obo:VO_0019166 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0019454 .

obo:VO_0007168 a rdfs:Class ;
  rdfs:label "Sipuleucel-T Vaccine" ;
  rdfs:comment "A cell-based vaccine composed of autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0001130 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae vaccine" ;
  rdfs:comment "a bacterial vaccine against A. pleuropneumoniae infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003535 .

obo:VO_0020143 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine Injection" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0003441 , obo:VO_0010444 , obo:VO_0010445 .

obo:VO_0005270 a rdfs:Class ;
  rdfs:label "1V270 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that includes IV270, which is a low-molecular weight TLR7 agonist conjugated to a phospholipid and is a highly potent and stable immune activator." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0010987 a rdfs:Class ;
  rdfs:label "FimH" ;
  rdfs:comment "Antibodies directed at the putative binding region of FimH (anti- s-FimH1-25) significantly reduced E. coli bladder infections in the experimental mouse model of urinary tract infections [PubMed: 9276729]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0007638 a rdfs:Class ;
  rdfs:label "MCMV-TRP2 vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0000080 a rdfs:Class ;
  rdfs:label "pBK-SFV DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0011266 a rdfs:Class ;
  rdfs:label "HslU" ;
  rdfs:comment "Study demonstrated that a recombinant construction of heat-shock protein (hslU) with lypopolysaccharide (rcHSP-LPS) administered 24 hours before inoculation induced resistance to S. typhimurium infection. Protection formed after 3 injections of rcHSP-LPS with 10 mcg in each or single injection with 100 mcg/mouse. Forty to eighty percent of immunized mice survived after challenge while 90% of control animals died. Destruction of the HSP by boiling of the construction led to loss of protective effect [PubMed: 19621817]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010776 .

obo:VO_0005329 a rdfs:Class ;
  rdfs:label "dmLT vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that includes double mutant of heat-labile E. coli toxin (LT) at R192G/L211A or LT(R192G/L211A)" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017292 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017247 , obo:VO_0017291 .

obo:VO_0000283 a rdfs:Class ;
  rdfs:label "herpesvirus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a herpesvirus as the vector." ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0007086 a rdfs:Class ;
  rdfs:label "Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine" ;
  rdfs:comment "A peptide vaccine preparation, containing recombinant human epidermal growth factor (rEGF) linked to the Neisseria meningitidis-derived recombinant immunogenic carrier protein P64k (rP64k) and mixed with the immunoadjuvant Montanide ISA 51, with potential active immunotherapy activity. Recombinant human EGF-rP64K/Montanide ISA 51 vaccine may trigger a humoral immune response against vaccine rEGF and rP64K and, so, against endogenous EGF. Antibody-mediated inhibition of endogenous EGF binding to its receptor, epithelial growth factor receptor (EGFR), may result in the inhibition of tumor cell proliferation." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000577 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0001163 a rdfs:Class ;
  rdfs:label "pathogen challenge protocol" ;
  rdfs:comment "pathogen challenge protocol is a protocol that is used for a pathogen challenge process." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:VO_0018912 a rdfs:Class ;
  rdfs:label "influenza B virus B/Singapore/WUH4618/2021 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010301 , obo:VO_0010415 .

obo:VO_0000020 a rdfs:Class ;
  rdfs:label "Brucella abortus strain RB51 vaccine vector" ;
  rdfs:comment "A bacterial vaccine vector that uses B. abortus vaccine strain RB51 as the vector." ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0020262 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 10 MG/ML" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0007600 a rdfs:Class ;
  rdfs:label "DNA vaccine encoding p42.3" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0001809 a rdfs:Class ;
  rdfs:label "Pseudorabies Modified Live Virus Vaccine (USDA: 1891.R4)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000750 , obo:VO_0001220 , obo:VO_0007748 .

obo:VO_0005465 a rdfs:Class ;
  rdfs:label "Non-US monovalent oral polio vaccine, unspecified formulation" ;
  rdfs:comment "A poliovirus vaccine that contains one type of  poliovirus and uses poliovirus particles that have been grown under controlled conditions and then killed to prevent disease caused from the vaccine." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010447 .

obo:OPL_0000033 a rdfs:Class ;
  rdfs:label "trypomastigote stage" ;
  rdfs:comment "A parasite lifecycle stage of trypanosomes. In trypomastigote stage, the kinetoplast is near the posterior end of the body, and the flagellum lies attached to the cell body for most of its length by an undulating membrane." ;
  rdfs:subClassOf obo:OPL_0000181 .

obo:VO_0004361 a rdfs:Class ;
  rdfs:label "Coxsackievirus DNA vaccine pCMV/VPl encoding VP1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001228 .

obo:VO_0019952 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0018475 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 10 by Gerke" ;
  rdfs:subClassOf obo:VO_0018455 .

obo:VO_0010875 a rdfs:Class ;
  rdfs:label "LcrV from Y. pestis KIM 10" ;
  rdfs:comment "An LcrV variant lacking amino acid residues 271 to 300 (rV10) elicited immune responses that protected mice against a lethal challenge with Y. pestis [PubMed: 16041032]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0020100 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.0000000385 MG/ML [Je-Vax]" ;
  rdfs:subClassOf obo:VO_0000066 , obo:VO_0020099 .

obo:VO_0004538 a rdfs:Class ;
  rdfs:label "BVDV DNA vaccine encoding E2" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001466 , obo:VO_0003061 .

obo:VO_0007174 a rdfs:Class ;
  rdfs:label "Renal Tumor-Reactive Autologous Peripheral Blood Lymphocyte Vaccine" ;
  rdfs:comment "Peripheral blood lymphocytes (PBL) harvested from the blood of a renal cancer patient and exposed in vitro to renal tumor-associated antigens (TAA). Introducing these renal tumor-reactive autologous peripheral blood lymphocytes back to the same patient target tumor cells expressing these TAAs and could induce a cytotoxic T-cell-mediated immune response against renal cell cancer." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0001986 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002361 .

obo:NCBITaxon_119210 a rdfs:Class ;
  rdfs:label "H3N2 subtype" ;
  rdfs:subClassOf obo:NCBITaxon_11320 .

obo:VO_0007423 a rdfs:Class ;
  rdfs:label "MUC1-KLH vaccine/QS21" ;
  rdfs:comment "A peptide vaccine containing the human tumor-associated antigen epithelial mucin (MUC1 antigen) conjugated with keyhole limpet hemocyanin (KLH) and combined with the nonspecific immunoadjuvant QS21, with potential antineoplastic activity. MUC1 antigen is linked with KLH, an immunostimulant and a hapten carrier, in order to enhance immune recognition; the co-administration of saponin-derived QS21 potentially amplifies the total immune response to the MUC1 antigen. Administration of MUC1-KLH vaccine/QS21 may result in both the production of antitumor antibodies and the stimulation of a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the MUC1 antigen. MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed as an aberrant or deglycosylated form in various cancers such as breast, prostate and ovarian cancers." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0018355 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003339 .

obo:VO_0019373 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine wistar strain PM-1503-3M (human), inactivated 2.5 UNT/ML Injection [Imovax]" ;
  rdfs:subClassOf obo:VO_0019372 , obo:VO_0020179 .

obo:VO_0007573 a rdfs:Class ;
  rdfs:label "Ad5F35-LMP1/LMP2-Transduced autologous dendritic cell vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0007270 a rdfs:Class ;
  rdfs:label "antigen-targeted Personalized Breast Cancer Vaccine" ;
  rdfs:comment "An individualized, therapeutic cancer vaccine (IVAC) composed of liposomes containing RNA encoding two or three tumor associated antigens (TAAs) that are specifically expressed in the patient's individual cancer selected from a warehouse (\"\"off the shelf\"\") and p53 RNA, with potential immunostimulatory and antineoplastic activities. Upon administration, the antigen-targeted personalized breast cancer vaccines are translated by antigen presenting cells (APCs) and the expressed protein is presented via major histocompatibility complex (MHC) molecules on the surface of the APCs. This leads to an induction of both cytotoxic T-lymphocyte (CTL) and memory T-cell immune responses against the TAAs. The RNAs in the vaccine are specifically selected for an individual patient after RNA profiling of the patient's tumor." ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0003408 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0012185 .

obo:VO_0002122 a rdfs:Class ;
  rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002393 , obo:VO_0007748 .

obo:BFO_0000031 a rdfs:Class ;
  rdfs:label "generically dependent continuant"@en ;
  rdfs:comment "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:PATO_0001678 a rdfs:Class ;
  rdfs:label "efficient" ;
  rdfs:comment "An efficiency quality inhering in a bearer by virtue of the bearer's having efficiency." ;
  rdfs:subClassOf obo:PATO_0001029 .

obo:VO_0017243 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Hepatitis B Surface Antigen Vaccine / tetanus toxoid vaccine, inactivated Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003172 .

obo:VO_0001122 a rdfs:Class ;
  rdfs:label "Saccharomyces cerevisiae vaccine vector" ;
  rdfs:comment "a recombinant vaccine vector that uses Saccharomyces cerevisiae as the vaccine vector" ;
  rdfs:subClassOf obo:VO_0001141 .

obo:OBI_0000067 a rdfs:Class ;
  rdfs:label "evaluant role"@en ;
  rdfs:comment "a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OPL_0000359 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii tachyzoite stage" ;
  rdfs:comment "A tachyzoite stage in the Toxoplasma gondii life cycle." ;
  rdfs:subClassOf obo:OPL_0000325 , obo:OPL_0000380 .

obo:VO_0002335 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Vaccine-Leptospira Hardjo-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002336 .

obo:VO_0000759 a rdfs:Class ;
  rdfs:label "contraceptive vaccine" ;
  rdfs:comment "A vaccine that is used to prevent conception." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:IAO_8000020 a rdfs:Class ;
  rdfs:label "EL++ ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000019 .

obo:VO_0020057 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML Injectable Suspension [Fluzone 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020479 .

obo:VO_0003697 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2015-2016 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003696 .

obo:VO_0016227 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 25 by Aca Mueller" ;
  rdfs:subClassOf obo:VO_0015906 .

obo:VO_0015955 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015729 , obo:VO_0015735 , obo:VO_0016045 .

obo:VO_0010868 a rdfs:Class ;
  rdfs:label "VP40 from Zaire ebolavirus" ;
  rdfs:comment """Vaccination of BALB/c or C57BL/6 mice with eVLPs, composed of the EBOV glycoprotein and matrix viral protein (VP)40 with a lipid membrane, in conjunction with QS-21 adjuvant resulted in mixed IgG subclass responses, a Th1-like memory cytokine response, and protection from lethal EBOV challenge [PubMed: 16002721].

VP40 expressed from alphavirus replicons induced a protective immune response in BALB/c mice when challenged with Ebola virus Zaire [PubMed: 11485406].""" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0004592 a rdfs:Class ;
  rdfs:label "Plasmodium yoelii DNA vaccine pPyHsp60-VR1012" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002514 .

obo:VO_0020046 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML [Fluarix 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020315 .

obo:VO_0011152 a rdfs:Class ;
  rdfs:label "GRP-78" ;
  rdfs:comment "BALB/c mice were immunized with a vaccine expressing the 78kDa (GRP-78) antigen of Leishmania donovani. Challenge infection was given intracardially after 2 weeks of second booster. A significant decrease in parasite burden was seen in vaccinees over the infected controls on all post challenge days and was found that maximum protection was provided by 78kDa+rIL-12 vaccine.  It was highly immunogenic as depicted by the reduction in parasite load (71-94.8%) [PubMed: 20093205]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0019598 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Nasal Spray [Flumist Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019592 , obo:VO_0020352 .

obo:VO_0000910 a rdfs:Class ;
  rdfs:label "vaccine allergen" ;
  rdfs:comment "vaccine allergen is a material entity that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals who has been vaccinated with a vaccine." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0000310 a rdfs:Class ;
  rdfs:label "vaccine emulsifier" ;
  rdfs:comment "a vaccine additive that stabilizes the vaccine emulsification manufacturing process and makes emulsion of the vaccine easier. " ;
  rdfs:subClassOf obo:VO_0000179 , obo:VO_0000850 .

obo:VO_0016020 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0015663 , obo:VO_0015818 .

obo:VO_0011524 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum DNA vaccine encoding TC0767/768" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012176 .

obo:VO_0016648 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Axicorp" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0005507 a rdfs:Class ;
  rdfs:label "Bl-Eng2 vaccine adjuvant" ;
  rdfs:comment "Vaccine adjuvant that is primarily composed of protein and actives innate immune pathways to induce a mixed Th1/Th2 response." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0007692 a rdfs:Class ;
  rdfs:label "melanoma helper peptide vaccine" ;
  rdfs:comment "A cancer vaccine consisting of peptides derived from melanoma-associated antigens and an adjuvant peptide derived from tetanus toxoid. Vaccination with this agent may stimulate a host cytotoxic T-cell response against tumor cells expressing melanoma-associated antigens, resulting in tumor cell lysis. Vaccines made from peptides may make the body build an immune response to kill tumor cells. Vaccines using melanoma peptides from cytotoxic T cells and helper T cells could work in treating patients with metastatic melanoma. This vaccine contains 12 melanoma peptides restricted by Human Leukocyte Antigen (HLA)-A1, -A2, or -A3 and 6 melanoma helper peptides restricted by HLA-DR molecules emulsified with sargramostim (Granulocyte-macrophage colony-stimulating factor, GM-CSF) and Montanide ISA-51 or Montanide ISA-51 VG (ISA-51)." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0007737 a rdfs:Class ;
  rdfs:label "transgenic lymphocyte immunization vaccine" ;
  rdfs:comment "A cancer vaccine made as patient's lymphocytes are rendered transgenic for a gene coding for selected portion of telomerase an enzyme expressed in the vast majority of cancer cells. Transgenic cells are then returned to the patient to produce an immune response targeted at cancer cells expressing telomerase. The transgenic cells serve as antigen- presenting cells (APCs) with the dual function of antigen synthesis and presentation. Vaccination produces an immune response targeting cancer cells expressing telomerase." ;
  rdfs:subClassOf obo:VO_0007657 , obo:VO_0007658 .

obo:VO_0010203 a rdfs:Class ;
  rdfs:label "meningococcal oligosaccharide (groups A, C, Y and W-135) diphtheria toxoid conjugate vaccine (MCV4O)" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0000168 a rdfs:Class ;
  rdfs:label "Salmonella gene" ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0010820 a rdfs:Class ;
  rdfs:label "Bordetella avium protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0017254 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Repevax]" ;
  rdfs:subClassOf obo:VO_0017252 .

obo:VO_0002352 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0001501 , obo:VO_0002336 .

obo:VO_0003461 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine, Inactivated 50 UNT/ML Injection [Vaqta]" ;
  rdfs:subClassOf obo:VO_0003466 .

obo:VO_0016273 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015923 .

obo:VO_0000748 a rdfs:Class ;
  rdfs:label "obsolete Papillomavirus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Papillomavirus." .

obo:VO_0015290 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0001871 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Rabies Modified Live Virus, Canarypox Vector Vaccine (USDA: 16T9.R0)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001021 , obo:VO_0002439 , obo:VO_0007748 .

obo:VO_0003808 a rdfs:Class ;
  rdfs:label "Flumist Quadrivalent 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000982 , obo:VO_0010433 .

obo:VO_0003369 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0003368 .

obo:VO_0015193 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension [Havrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015192 , obo:VO_0015195 , obo:VO_0015277 .

obo:VO_0019238 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020344 .

obo:NCBITaxon_1513 a rdfs:Class ;
  rdfs:label "Clostridium tetani" ;
  rdfs:subClassOf obo:NCBITaxon_1485 .

obo:VO_0017836 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Prefilled Syringe [Mastaflu]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017888 .

obo:VO_0015272 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0015267 .

obo:VO_0020795 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 800000000 CELLS [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020794 .

obo:VO_0005316 a rdfs:Class ;
  rdfs:label "Noora vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine by Bagheiat-allah University of Medical Sciences" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0018505 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0018502 .

obo:VO_0019869 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Injectable Suspension [Flulaval Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020342 .

obo:VO_0001049 a rdfs:Class ;
  rdfs:label "Vaxsafe MS vaccine" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000949 , obo:VO_0001077 .

obo:VO_0017899 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0004837 .

obo:VO_0003540 a rdfs:Class ;
  rdfs:label "Orthohepadnavirus vaccine" ;
  rdfs:comment "Vaccine that protects against Orthohepadnavirus infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000563 .

obo:VO_0004193 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum LSA-3 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0004913 a rdfs:Class ;
  rdfs:label "virus-like particle vaccine role" ;
  rdfs:comment "A vaccine role that inheres in a vaccine using virus-like particles (VLPs), multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccines." ;
  rdfs:subClassOf obo:VO_0000615 .

obo:VO_0016680 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated Injectable Suspension [Boostrix]" ;
  rdfs:subClassOf obo:VO_0016706 .

obo:VO_0019496 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / meningococcal group C polysaccharide / meningococcal polysaccharide vaccine group Y Injection [MenHibrix]" ;
  rdfs:subClassOf obo:VO_0000031 , obo:VO_0000561 , obo:VO_0003192 , obo:VO_0020832 .

obo:VO_0001416 a rdfs:Class ;
  rdfs:label "Mycoplasma gallisepticum gene" ;
  rdfs:comment "A bacterial gene that is from Mycoplasma gallisepticum." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0002953 a rdfs:Class ;
  rdfs:label "Classical swine fever virus E1 mutant vaccine" ;
  rdfs:comment "An N to A amino acid substitution was made in the N594 site of the E1 glycoprotein, resulting in attenuation of the virus in swine. This attenuated virus induced protection against challenge with wild type CSFV" ;
  rdfs:subClassOf obo:VO_0001012 .

obo:VO_0019941 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Afluria 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0004914 , obo:VO_0020301 .

obo:VO_0017366 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / tetanus toxoid vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000943 , obo:VO_0001214 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0018875 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0020603 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020884 .

obo:VO_0007253 a rdfs:Class ;
  rdfs:label "Androgen Receptor Ligand-binding Domain-encoding Plasmid DNA Vaccine MVI-118" ;
  rdfs:comment "A cancer vaccine containing pTVG4 plasmid DNA encoding the human androgen receptor (AR) ligand-binding domain (LBD) (pTVG-AR), with potential immunostimulating and antineoplastic activities. Upon intradermal administration of AR LBD-encoding plasmid DNA vaccine MVI-118, the plasmid DNA vaccine expresses AR LBD and may stimulate the host immune system to generate a cytotoxic T-lymphocyte (CTL) response against AR LBD-expressing prostate cancer cells. This reduces proliferation of AR-expressing tumor cells. AR, a tumor-associated antigen (TAA) overexpressed in prostate cancer cells, plays a key role in the development and progression of prostate cancer; its expression is correlated with poor prognosis." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0002375 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000639 , obo:VO_0000963 , obo:VO_0002377 .

obo:VO_0003965 a rdfs:Class ;
  rdfs:label "Heplisav-B Injectable Product" ;
  rdfs:subClassOf obo:VO_0003152 .

obo:OGG_2060224914 a rdfs:Class ;
  rdfs:label "protein-coding gene of Brucella melitensis bv. 1 str. 16M" ;
  rdfs:comment "A gene of Brucella melitensis bv. 1 str. 16M that has a protein-coding gene disposition" ;
  rdfs:subClassOf obo:OGG_2000224914 .

obo:VO_0015738 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 25" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015803 .

obo:IDO_0000450 a rdfs:Class ;
  rdfs:label "pathogenic disposition"@en ;
  rdfs:comment "A disposition to initiate processes that result in a disorder."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:VO_0000243 a rdfs:Class ;
  rdfs:label "assay of CFU reduction in spleen" ;
  rdfs:comment "assay of CFU reduction in spleen is a CFU reduction assay that is measured using the extracted spleen as the tissue for isolation of infected pathogens." ;
  rdfs:subClassOf obo:VO_0000242 .

obo:VO_0004282 a rdfs:Class ;
  rdfs:label "Focetria vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0002094 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus, Canarypox Vector Vaccine (USDA: 1331.R1)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002413 , obo:VO_0007748 .

obo:VO_0007022 a rdfs:Class ;
  rdfs:label "Tn(c)-KLH Conjugate Vaccine" ;
  rdfs:comment "A vaccine containing a clustered pancarcinoma carbohydrate antigen conjugated with keyhole limpet hemocyanin (KLH) with potential antineoplastic activity. Alpha-N-acetylgalactosamine (Tn) is a monosaccharide usually O-linked to serine or threonine residues of mucins found on most epithelial cancers with the highest expression on prostate cancer. This vaccine contains the Tn epitope cluster (c) that is synthesized by linking 3 copies of the Tn epitope on a threonine backbone to achieve the essential immunogenic structure. KLH is a hapten carrier and serves as an immunostimulant to improve immune recognition. Vaccination with Tn(c)-KLH vaccine may produce antibodies and elicit a cytotoxic T lymphocyte (CTL) response against those tumor cells expressing Tn antigen, resulting in decreased tumor growth." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000534 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0007157 a rdfs:Class ;
  rdfs:label "PSMA/TARP Peptide Vaccine" ;
  rdfs:comment "A peptide-based cancer vaccine containing epitopes of T cell receptor gamma-chain alternate reading frame protein (TARP) and prostate-specific membrane antigen (PSMA) in combination with a Poly IC-LC immunoadjuvant, with potential antineoplastic activity. Upon administration, PSMA/TARP peptide vaccine may stimulate a host cytotoxic T-cell (CTL) response against TARP- and PSMA-expressing tumor cells, resulting in tumor cell cytotoxicity. The nuclear protein TARP and PSMA are commonly expressed in prostate cancer cells." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0004408 a rdfs:Class ;
  rdfs:label "Pristane-induced arthritis DNA vaccine DNA-hsp65 encoding Mycobacterium leprae 65-kDa heat shock protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0002823 .

obo:VO_0016188 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0015901 .

obo:VO_0004207 a rdfs:Class ;
  rdfs:label "Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML" ;
  rdfs:subClassOf obo:VO_0003199 .

obo:VO_0002246 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47L9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002402 , obo:VO_0007748 .

obo:VO_0011456 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum PmpE/F-2 protein vaccine" ;
  rdfs:subClassOf obo:VO_0012176 .

obo:VO_0010893 a rdfs:Class ;
  rdfs:label "PmpE/F-2" ;
  rdfs:comment "Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection.  In addition, pmpE/F-2 was able to engender protective immunity against challenge with C. muridarum [PubMed: 19155509]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010795 .

obo:VO_0019871 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Flulaval Quad 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020342 .

obo:VO_0000307 a rdfs:Class ;
  rdfs:label "KKF24 vaccine" ;
  rdfs:comment "KKF24 is a recombinant strain of Francisella novicida U112 with iglC mutation (F. novicida delta-iglC::ermC). PMID:14680699." ;
  rdfs:subClassOf obo:VO_0000152 .

obo:DOID_11100 a rdfs:Class ;
  rdfs:label "Q fever"@en ;
  rdfs:comment "A primary bacterial infectious disease that is a zoonotic infectious disease affecting multiple organs, has_material_basis_in Coxiella burnetii, which is transmitted_by inhalation of air contaminated by barnyard dust containing dried placental material, birth fluids, or excreta of infected herd animals, transmitted_by ingestion of contaminated milk, transmitted_by tick bites and transmitted_by contact with infected person. The infection has_symptom fever, has_symptom headache, has_symptom cough, has_symptom pleuritic chest pain, has_symptom myalgia and has_symptom arthralgia."@en ;
  rdfs:subClassOf obo:DOID_0050338 .

obo:VO_0005148 a rdfs:Class ;
  rdfs:label "SARS NDV-VF/S vaccine" ;
  rdfs:comment "A SARS-CoV recombinant vector vaccine that is made from the Newcastle disease virus from  the lentogenic LaSota strain expressing SARS-CoV S protein." ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0007645 a rdfs:Class ;
  rdfs:label "multi-epitope folate receptor alpha-loaded dendritic cell vaccine" ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0017128 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0017073 .

obo:VO_0000936 a rdfs:Class ;
  rdfs:label "Suvaxyn Aujeszky vaccine" ;
  rdfs:comment "A vaccine that is made of a TK-negative (TK -) and gI/gE-negative (gI/gE -) pseudorabies virus (PRV) mutant to protect pigs against Aujeszky's disease. Aujeszky's disease is also known as pseudorabies. It is a disease primarily of pigs and is caused by porcine herpesvirus 1. This disease is characterized by respiratory, reproductive and nervous signs." ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000750 .

obo:NCBITaxon_5693 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi" ;
  rdfs:subClassOf obo:NCBITaxon_5690 .

obo:VO_0003062 a rdfs:Class ;
  rdfs:label "Murid herpesvirus 1 vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Murine Cytomegalovirus (or called murid herpesvirus 1)." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000727 .

obo:VO_0003712 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003711 .

obo:VO_0015123 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML Injectable Solution [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015122 , obo:VO_0015287 .

obo:VO_0011247 a rdfs:Class ;
  rdfs:label "ORF67" ;
  rdfs:comment "Monoclonal antibodies to gI neutralize VZV in vitro in a complement- dependent manner [PubMed: 3021804]. Guinea pigs immunized with recombinant varicella-zoster virus (VZV) glycoproteins E (gE) and I (gI) developed antigen-specific antibodies in the sera, vitreous, and conjunctival washes. Sera from immunized animals neutralized both cell-free and cell-associated VZV, and peripheral blood lymphocytes proliferated in vitro in response to recombinant gE and gI and to antigens from VZV-infected cells. Immunized guinea pigs were inoculated intravitreally with VZV, which induces chronic uveitis. VZV DNA was more rapidly cleared and infectious VZV was isolated less frequently from the retinas of animals immunized with gE and gI compared with that in controls receiving adjuvant alone [PubMed: 9697709]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010792 .

obo:VO_0020326 a rdfs:Class ;
  rdfs:label "Flublok Quadrivalent 2021-2022 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003067 , obo:VO_0010423 .

obo:VO_0015186 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 CELLS/ML Injectable Suspension [Hepatyrix] Box of 50 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015185 .

obo:VO_0017207 a rdfs:Class ;
  rdfs:label "1 ML tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution [Tetabulin] Box of 1" ;
  rdfs:subClassOf obo:VO_0017206 , obo:VO_0017210 , obo:VO_0017535 .

obo:VO_0018117 a rdfs:Class ;
  rdfs:label "Measles Vaccine / Mumps Vaccine / Rubella virus vaccine / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution [ProQuad]" ;
  rdfs:subClassOf obo:VO_0000091 , obo:VO_0018115 .

obo:VO_0005292 a rdfs:Class ;
  rdfs:label "EmT4 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0005340 a rdfs:Class ;
  rdfs:label "VB10.2129 vaccine" ;
  rdfs:comment "A SARS-CoV-2 DNA vaccine developed by Vaccibody AS encoding the receptor-binding domain" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005203 .

obo:NCBITaxon_83560 a rdfs:Class ;
  rdfs:label "Chlamydia muridarum" ;
  rdfs:subClassOf obo:NCBITaxon_810 .

obo:VO_0017668 a rdfs:Class ;
  rdfs:label "Diphtheria-Tetanus-Poliovirus-Influenza B vaccine" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0000664 , obo:VO_0000732 , obo:VO_0003495 .

obo:VO_0002977 a rdfs:Class ;
  rdfs:label "human metapneumovirus M2-2 mutant vaccine" ;
  rdfs:comment "An M2-2 mutant is attenuated in African green monkeys and induced protection from challenge with wild type HMPV" ;
  rdfs:subClassOf obo:VO_0002511 .

obo:VO_0017522 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension [Tetravac]" ;
  rdfs:subClassOf obo:VO_0017520 , obo:VO_0017521 .

obo:NCBITaxon_780 a rdfs:Class ;
  rdfs:label "Rickettsia" ;
  rdfs:subClassOf obo:NCBITaxon_766 .

obo:VO_0019116 a rdfs:Class ;
  rdfs:label "0.25 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020489 .

obo:VO_0015604 a rdfs:Class ;
  rdfs:label "1 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015558 .

obo:VO_0003202 a rdfs:Class ;
  rdfs:label "Bordetella pertussis fimbriae 2/3 vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003196 .

obo:VO_0004451 a rdfs:Class ;
  rdfs:label "Prostate cancer DNA vaccine encoding PSCA" ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0004254 a rdfs:Class ;
  rdfs:label "recombinant NY-ESO-1 ISCOMATRIX vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0004489 a rdfs:Class ;
  rdfs:label "WEE virus DNA vaccine pVHX-6 encoding 26S" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012188 .

obo:VO_0005008 a rdfs:Class ;
  rdfs:label "VR10551 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label VR10551.  This plasmid contains a human cytomegalovirus immediate early 1 promoter, a kanamycin resistance gene, intron A and a modified rabbit b-globin terminator." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015922 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 3" ;
  rdfs:subClassOf obo:VO_0015631 , obo:VO_0015688 , obo:VO_0016030 .

obo:VO_0010085 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii CDPK1" ;
  rdfs:comment "A CDPK1 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:VO_0002033 a rdfs:Class ;
  rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.10 )" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002326 , obo:VO_0007748 .

obo:VO_0015671 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015597 .

obo:VO_0016720 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0016704 , obo:VO_0016706 .

obo:VO_0003141 a rdfs:Class ;
  rdfs:label "CV9201 vaccine" ;
  rdfs:comment "A non-small cell lung cancer mRNA-derived vaccine that contains modified mRNAs encoding cancer-testis antigen NY-ESO-1, melanoma-associated antigens C1 (MAGE-C1/CT7) and C2 (MAGE-C2/CT10), survivin, and the oncofetal antigen 5T4 with potential antitumor and immunomodulatory activities." ;
  rdfs:subClassOf obo:VO_0003140 , obo:VO_0007657 .

obo:NCBITaxon_5866 a rdfs:Class ;
  rdfs:label "Babesia bigemina" ;
  rdfs:subClassOf obo:NCBITaxon_5864 .

obo:VO_0010272 a rdfs:Class ;
  rdfs:label "sacrifice process datum" ;
  rdfs:comment "A measurment datum that records the method of sacrifice (i.e. killing). " ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:NCBITaxon_194 a rdfs:Class ;
  rdfs:label "Campylobacter" ;
  rdfs:subClassOf obo:NCBITaxon_213849 .

obo:VO_0001344 a rdfs:Class ;
  rdfs:label "LTK72 vaccine adjuvant" ;
  rdfs:comment "An E. coli LT toxin derived vaccine adjuvant that is a mutant form of heat-labile Escherichia coli enterotoxin (LT) that contains a substitution Ala -> Arg  in position 72 of the A subunit." ;
  rdfs:subClassOf obo:VO_0000388 .

obo:VO_0003289 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003334 .

obo:VO_0020449 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typhim VI] Box of 1" ;
  rdfs:subClassOf obo:VO_0020430 , obo:VO_0020474 .

obo:CL_0000255 a rdfs:Class ;
  rdfs:label "eukaryotic cell" ;
  rdfs:comment "Any cell that in taxon some Eukaryota." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:NCBITaxon_3379134 a rdfs:Class ;
  rdfs:label "Pseudomonadati" ;
  rdfs:subClassOf obo:NCBITaxon_2 .

obo:VO_0010169 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine, pediatric/adolescent dosage, 2 dose schedule" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 .

obo:VO_0011542 a rdfs:Class ;
  rdfs:label "Leishmania donovani DNA vaccine encoding NH36 Protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0001142 .

obo:VO_0016971 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 50 LFU/ML / Pertussis Vaccine 24 UNT/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Solution by Aventis" ;
  rdfs:subClassOf obo:VO_0016970 .

obo:VO_0018416 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 7F vaccine 0.002 MG/ML" ;
  rdfs:subClassOf obo:VO_0003253 .

obo:VO_0015552 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Hevac B]" ;
  rdfs:subClassOf obo:VO_0003419 .

obo:VO_0017749 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] Box of 20" ;
  rdfs:subClassOf obo:VO_0017747 , obo:VO_0017752 .

obo:VO_0000478 a rdfs:Class ;
  rdfs:label "E. coli vaccine using intimin polypeptide" ;
  rdfs:subClassOf obo:VO_0000628 , obo:VO_0001466 .

obo:VO_0018236 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0018233 .

obo:VO_0002057 a rdfs:Class ;
  rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.03)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002385 , obo:VO_0007748 .

obo:VO_0004131 a rdfs:Class ;
  rdfs:label "M-44 vaccine" ;
  rdfs:subClassOf obo:VO_0000463 .

obo:VO_0003022 a rdfs:Class ;
  rdfs:label "subcutaneous vaccination" ;
  rdfs:comment "vaccination process that occurs in the subcutaneous route" ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0016977 a rdfs:Class ;
  rdfs:label "0.5 ML Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.02 MG/ML Injection [Hiberix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0016976 .

obo:VO_0002454 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis Vaccine-Mycoplasma Gallisepticum Bacterin" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0001222 , obo:VO_0001502 .

obo:VO_0016126 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 25 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015879 .

obo:VO_0001892 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4129.00)" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000455 , obo:VO_0000563 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002340 .

obo:VO_0007286 a rdfs:Class ;
  rdfs:label "autologous dendritic cell-allogeneic melanoma tumor cell lysate vaccine" ;
  rdfs:comment "A cell-based vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from heat-treated allogeneic melanoma tumor cells. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T-cell and antibody responses to melanoma cells bearing shared melanoma antigens such as MelanA/MART-1, gp100, MAGE3, resulting in tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0004699 a rdfs:Class ;
  rdfs:label "PrV-PCV2-ORF2 vaccine" ;
  rdfs:subClassOf obo:VO_0001524 .

obo:VO_0000840 a rdfs:Class ;
  rdfs:label "recombinant Yersinia rV10 vaccine" ;
  rdfs:comment "A Y. pestis vaccine that uses the recombinant V10 (rV10), a variant (lacking residues 271 to 300) of Yersinia pestis LcrV. PMID:16861680." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000648 .

obo:VO_0007001 a rdfs:Class ;
  rdfs:label "Recombinant Adenovirus-Interferon/Syn3 Vaccine" ;
  rdfs:comment "A non-replicating recombinant adenovirus type 5 (Ad5)-vector encoding the gene for interferon alpha-2b (IFN_2b) and the gene transfer enhancement agent Syn 3, with potential antineoplastic activity. Upon intravesical administration, recombinant adenovirus-interferon with Syn3 transfects both cancerous and normal bladder cells, and the adenovirus secretes interferon (IFN_2b) into the bladder. IFN exerts a direct antitumor killing effect and a bystander effect, thereby killing adjacent, non-transfected cancerous bladder cells. Syn 3 enhances the ability of the adenoviral vector to transfect cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005485 , obo:VO_0007657 .

obo:VO_0019327 a rdfs:Class ;
  rdfs:label "0.5 ML L1 protein, human papillomavirus type 11 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 16 vaccine 0.08 MG/ML / L1 protein, human papillomavirus type 18 vaccine 0.04 MG/ML / L1 protein, human papillomavirus type 6 vaccine 0.04 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0020109 .

obo:VO_0010886 a rdfs:Class ;
  rdfs:label "TC0757 hypothetical protein" ;
  rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0757 showed significant levels of protection when compared to negative control animals [PubMed: 17239501]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010795 .

obo:VO_0020683 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020675 .

obo:VO_0017833 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Prefilled Syringe [Enzira]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017888 .

obo:VO_0001056 a rdfs:Class ;
  rdfs:label "measles virus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a measles virus strain" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0020963 a rdfs:Class ;
  rdfs:label "Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.009 MG/ML" ;
  rdfs:subClassOf obo:VO_0003526 .

obo:DOID_574 a rdfs:Class ;
  rdfs:label "peripheral nervous system disease"@en ;
  rdfs:comment "A nervous system disease that affects the peripheral nervous system."@en ;
  rdfs:subClassOf obo:DOID_863 .

obo:VO_0001952 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44M5.22)" ;
  rdfs:subClassOf obo:VO_0002359 .

obo:NCBITaxon_151341 a rdfs:Class ;
  rdfs:label "Polyomaviridae" ;
  rdfs:subClassOf obo:NCBITaxon_2732421 .

obo:VO_0016767 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0016719 .

obo:VO_0002020 a rdfs:Class ;
  rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Clostridium Perfringens Types C & D-Escherichia Coli Bacterin-Toxoid (USDA: 4575.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0000974 , obo:VO_0002376 .

obo:VO_0000907 a rdfs:Class ;
  rdfs:label "surface antigens from the zona pellucida" ;
  rdfs:subClassOf obo:OBI_1110034 .

obo:VO_0016076 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Gerke" ;
  rdfs:subClassOf obo:VO_0015868 .

obo:VO_0003831 a rdfs:Class ;
  rdfs:label "Havrix, Hepatitis A Vaccine (Inactivated), (Pediatric Dose) 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0003833 .

obo:VO_0020888 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Afluria]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:NCBITaxon_1311 a rdfs:Class ;
  rdfs:label "Streptococcus agalactiae" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:VO_0019894 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension [Fluvirin 2013-2014 Formula]" ;
  rdfs:subClassOf obo:VO_0019889 , obo:VO_0020476 .

obo:VO_0016320 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015934 .

obo:VO_0020075 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003499 , obo:VO_0004914 , obo:VO_0010415 .

obo:VO_0018025 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 1000000 CELLS / poliovirus vaccine inactivated, type 2 (MEF-1) 100000 CELLS / poliovirus vaccine inactivated, type 3 (Saukett) 300000 CELLS Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020168 .

obo:VO_0016912 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Boostrix] by GSK" ;
  rdfs:subClassOf obo:VO_0016911 .

obo:IAO_0000005 a rdfs:Class ;
  rdfs:label "objective specification"@en ;
  rdfs:comment "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:VO_0015832 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Suspension [Fendrix] by GSK" ;
  rdfs:subClassOf obo:VO_0015626 .

obo:VO_0003726 a rdfs:Class ;
  rdfs:label "afluria 2016-2017 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003725 .

obo:VO_0007551 a rdfs:Class ;
  rdfs:label "HLA-A1, A2, B35-restricted survivin peptide/montanide ISA-51 vaccine" ;
  rdfs:comment "A peptide vaccine comprised of synthetic HLA-A1, -A2 and -B35 restricted survivin epitopes combined with the adjuvant Montanide ISA-51 with potential antineoplastic activity. Upon administration, HLA-A1, A2, B35-restricted survivin peptides/Montanide ISA-51 vaccine may stimulate a cytotoxic T cell response against tumor cells that overexpress survivin, resulting in tumor cell lysis. Montanide ISA-51, also known as incomplete Freund's adjuvant or IFA, is a stabilized water-in-oil emulsion adjuvant containing mineral oil with mannide oleate added as a surfactant that non-specifically stimulates cell-mediated immune responses to antigens." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0019700 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0018785 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / pertactin adsorbed 0.005 MG/ML / Pertussis Vaccine 0.016 MG/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0001997 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.25)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002364 .

obo:VO_0003297 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ;
  rdfs:subClassOf obo:VO_0003337 .

obo:NCBITaxon_11974 a rdfs:Class ;
  rdfs:label "Caliciviridae" ;
  rdfs:subClassOf obo:NCBITaxon_464095 .

obo:VO_0018174 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 700 PFU/ML [Priorix]" ;
  rdfs:subClassOf obo:VO_0018173 .

obo:VO_0018310 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0018284 .

obo:VO_0002512 a rdfs:Class ;
  rdfs:label "Human respiratory syncytial virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection of Human respiratory syncytial virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0017781 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 0.016 MG/ML Injectable Suspension [Boostrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0017780 , obo:VO_0017785 .

obo:NCBITaxon_1891747 a rdfs:Class ;
  rdfs:label "Gammapolyomavirus avis" ;
  rdfs:subClassOf obo:NCBITaxon_151341 .

obo:VO_0015713 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 20" ;
  rdfs:subClassOf obo:VO_0015571 , obo:VO_0015790 .

obo:VO_0018851 a rdfs:Class ;
  rdfs:label "yellow fever virus strain 17D-204 live antigen 2000 UNT/ML [Stamaril]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010456 .

obo:VO_0004394 a rdfs:Class ;
  rdfs:label "Brucella melitensis DNA vaccine pCI-Omp31" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000709 .

obo:VO_0004576 a rdfs:Class ;
  rdfs:label "Hantavirus DNA vaccine pWRG/HTN-M" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012167 .

obo:VO_0010307 a rdfs:Class ;
  rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003498 , obo:VO_0010297 .

obo:VO_0015067 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0010444 .

obo:VO_0020565 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippeimpfstoff Ratiopharm]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020865 .

obo:VO_0017861 a rdfs:Class ;
  rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.008 MG/ML" ;
  rdfs:subClassOf obo:VO_0004860 .

obo:VO_0017951 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Menjugate] Box of 1" ;
  rdfs:subClassOf obo:VO_0017905 .

obo:VO_0006010 a rdfs:Class ;
  rdfs:label "hepatitis A vaccine pediatric dosage unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 .

obo:CL_0000182 a rdfs:Class ;
  rdfs:label "hepatocyte" ;
  rdfs:comment "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." ;
  rdfs:subClassOf obo:CL_0000255 .

obo:VO_0003018 a rdfs:Class ;
  rdfs:label "intragastric vaccination" ;
  rdfs:comment "vaccination that occurs in the intagastric route." ;
  rdfs:subClassOf obo:VO_0000002 .

obo:VO_0020927 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0003502 , obo:VO_0004914 .

obo:VO_0007576 a rdfs:Class ;
  rdfs:label "obsolete Autologous Dendritic Cell Vaccine ACT2001" .

obo:VO_0002572 a rdfs:Class ;
  rdfs:label "virB2 from B. abortus" ;
  rdfs:comment "A virB2 mutant is attenuated in Brucella melitensis and provides protection in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0000793 .

obo:VO_0004639 a rdfs:Class ;
  rdfs:label "ALVAC-rabies vaccine" ;
  rdfs:subClassOf obo:VO_0000650 .

obo:VO_0015578 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015496 , obo:VO_0015545 .

obo:VO_0015615 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO]" ;
  rdfs:subClassOf obo:VO_0015567 , obo:VO_0015660 .

obo:NCBITaxon_27592 a rdfs:Class ;
  rdfs:label "Bovinae" ;
  rdfs:subClassOf obo:NCBITaxon_9895 .

obo:VO_0002637 a rdfs:Class ;
  rdfs:label "guaB from Salmonella Typhimurium" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0017679 a rdfs:Class ;
  rdfs:label "BCG, live, Connaught strain" ;
  rdfs:subClassOf obo:VO_0000771 .

obo:VO_0000042 a rdfs:Class ;
  rdfs:label "pBHT DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0004707 a rdfs:Class ;
  rdfs:label "Myxoma-FCV vaccine" ;
  rdfs:subClassOf obo:VO_0001509 .

obo:VO_0010018 a rdfs:Class ;
  rdfs:label "Leishmania  donovani KH" ;
  rdfs:comment "A KH protein that is part of Leishmania  donovani" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010832 .

obo:VO_0020545 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Begripal] Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0020544 .

obo:VO_0007275 a rdfs:Class ;
  rdfs:label "Autologous Ad-CD154-Transduced CLL B Cells Vaccine" ;
  rdfs:comment "An autologous tumor cell vaccine containing chronic lymphocytic leukemia (CLL) B cells transduced with an adenoviral vector carrying chimeric CD154 (ad-CD154) with potential antineoplastic activity. Administration of autologous ad-CD154 transduced CLL B cells may result in increases in the numbers of leukemia-specific CD4+ T cells and high serum-levels of IL-12 and IFN-gamma. Due to ligation of CD154 to CD40 on CLL cells, this agent may induce CLL cells to express the proapoptotic molecule BID and death receptors CD95 (Fas) and DR5, rendering CLL B cells first resistant and then sensitive to Fas-mediated apoptosis. In addition, autologous ad-CD154 transduced CLL B cells may induce MHC class I-dependent cytotoxic T lymphocyte (CTL) responses against autologous leukemia cells. CD154 is a type II membrane glycoprotein and ligand for CD40; both molecules are important in cognate co-stimulatory cell-cell interactions." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0004297 a rdfs:Class ;
  rdfs:label "influenza virus DNA vaccine pIRES/NA/IL-2 encoding NA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000642 .

obo:VO_0000399 a rdfs:Class ;
  rdfs:label "vaccine-induced T cell interferon-gramm production boosted by IL-15 vaccine adjuvant" ;
  rdfs:comment "A vaccine-induced adjuvant boosted T cell interferon-gramm production that results from the addition of a IL-15 vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000383 .

obo:NCBITaxon_91347 a rdfs:Class ;
  rdfs:label "Enterobacterales" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OBI_0200000 a rdfs:Class ;
  rdfs:label "data transformation"@en ;
  rdfs:comment "A planned process that produces output data from input data."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VO_0011502 a rdfs:Class ;
  rdfs:label "Cryptosporidium. parvum DNA vaccine encoding CP15/61" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012160 .

obo:VO_0000455 a rdfs:Class ;
  rdfs:label "prophylactic vaccine" ;
  rdfs:comment "a vaccine that is used for prevention against a disease." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:DOID_0050338 a rdfs:Class ;
  rdfs:label "primary bacterial infectious disease"@en ;
  rdfs:comment "A bacterial infectious disease that results_in infection by bacteria as a result of their presence or activity within the normal, healthy host, and their intrinsic virulence is, in part, a necessary consequence of their need to reproduce and spread."@en ;
  rdfs:subClassOf obo:DOID_104 .

obo:VO_0015250 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML [Epaxal]" ;
  rdfs:subClassOf obo:VO_0010713 , obo:VO_0015249 .

obo:VO_0020164 a rdfs:Class ;
  rdfs:label "pertussis vaccine 0.0468 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017808 .

obo:VO_0003943 a rdfs:Class ;
  rdfs:label "Human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML" ;
  rdfs:subClassOf obo:VO_0003941 .

obo:VO_0015655 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension Box of 3" ;
  rdfs:subClassOf obo:VO_0015559 , obo:VO_0015601 .

obo:VO_0016087 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 20 by Mtk" ;
  rdfs:subClassOf obo:VO_0015870 .

obo:VO_0015330 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated 320 UNT/ML / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML [Vivaxim]" ;
  rdfs:subClassOf obo:VO_0010748 , obo:VO_0015329 .

obo:VO_0017765 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017762 .

obo:VO_0007554 a rdfs:Class ;
  rdfs:label "HLA-A0201-Restricted TRP2-gp100-EphA2-HER2 multipeptide vaccine" ;
  rdfs:comment "A cancer vaccine containing four HLA-A0201-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Vaccine peptide epitopes are derived from the tumor associated antigens (TAAs) tyrosinase-related protein 2 (TRP2), glycoprotein 100 (gp100), Ephrin receptor A2 (EphA2) and human epidermal growth factor receptor 2 (HER2). Upon administration, HLA-A0201-restricted TRp2-gp100-EphA2-HER2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against TRP2-gp100-EphA2-HER2-expressing tumor cells, resulting in tumor cell lysis and decreased tumor cell proliferation. HLA-A0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0005398 a rdfs:Class ;
  rdfs:label "MIPSCo-mRNA-RBD-1 vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by the University of Melbourne." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0011374 a rdfs:Class ;
  rdfs:label "Phleum pratense allergy Phl p 12 subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0001362 .

obo:VO_0016887 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0016879 .

obo:VO_0010922 a rdfs:Class ;
  rdfs:label "PotF" ;
  rdfs:comment "PotF was evaluated as an antigen for a vaccine candidate against B. pseudomallei infection. Nonmembrane regions of the B. pseudomallei protein was expressed and purified from Escherichia coli and then evaluated as a vaccine candidate in an established mouse model of B. pseudomallei infection. When delivered with the monophosphoryl lipid A-trehalose dicorynomycolate adjuvant, the protein stimulated antigen-specific humoral and cellular immune responses. Immunization with the PotF protein domain afforded significant protection against a subsequent challenge with B. pseudomallei [PubMed: 17517877]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010840 .

obo:VO_0007408 a rdfs:Class ;
  rdfs:label "KLH-FITC vaccine" ;
  rdfs:comment "A conjugate consisting of keyhole-limpet hemocyanin (KLH) and fluorescein isothiocyanate (FITC) with potential immunostimulating activity. Vaccination with KLH-FITC may elicit an immune response against fluorescein and the production of anti-fluorescein IgG antibodies. KLH, a natural protein isolated from the marine mollusk keyhole limpet, is an immunostimulant carrier protein." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0007064 a rdfs:Class ;
  rdfs:label "Recombinant Vaccinia Viral Vector RO5217790 Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a modified, replication-defective, vaccinia virus Ankara (MVA) strain encoding the tumor-associated antigens (TAAs) human papillomavirus type 16 (HPV16) subtypes E6 and E7, and human interleukin-2 (IL-2), with potential immunostimulating and antineoplastic activities. Vaccination with MVA-HPV16E6/E7-IL2 vaccine TG4001 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing HPV16 E6 and E7, resulting in tumor cell lysis. Expression of IL-2 augments the specific CTL response against HPV16 E6- and E7-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005488 , obo:VO_0007657 .

obo:VO_0003755 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2018-2019 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003752 .

obo:VO_0010124 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii TgPF" ;
  rdfs:comment "A TgPF protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0000181 a rdfs:Class ;
  rdfs:label "lipopolysaccharide vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant made from bacterial lipopolysaccharide (LPS) of gram-negative bacteria." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0000146 a rdfs:Class ;
  rdfs:label "Corynebacterium-derived P40 vaccine adjuvant" ;
  rdfs:comment "A microbial derivative vaccine adjuvant that is the P40 particulate fraction isolated from Corynebacterium." ;
  rdfs:subClassOf obo:VO_0000118 .

obo:VO_0007673 a rdfs:Class ;
  rdfs:label "hodgkin's antigens-GM-CSF-expressing cell vaccine" ;
  rdfs:comment "A cancer vaccine consisting of Hodgkin lymphoma cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Hodgkin antigens-GM-CSF-expressing cell vaccine may stimulate a cytotoxic T-lymphocyte (CTL) immune response against Hodgkin lymphoma-associated antigens, which may result in the lysis of tumor cells expressing these antigens. Also, transfected Hodgkin lymphoma cells secrete GM-CSF, which may potentiate the CTL response against Hodgkin lymphoma-associated antigens. Vaccines made from a tumor antigen may help the body build an effective immune response to kill tumor cells. This vaccine contains cells expressing Hodgkin's antigens and GM-CSF, and could cause an immunological response in Hodgkin's lymphoma patients." ;
  rdfs:subClassOf obo:VO_0005427 , obo:VO_0007657 , obo:VO_0007658 .

obo:IAO_8000008 a rdfs:Class ;
  rdfs:label "analysis subset ontology module"@en ;
  rdfs:comment "An ontology module that is intended for usage in analysis or discovery applications."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:VO_0000450 a rdfs:Class ;
  rdfs:label "NPAP Brucella vaccine" ;
  rdfs:subClassOf obo:VO_0000108 , obo:VO_0001214 .

obo:VO_0015695 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015567 , obo:VO_0015784 .

obo:VO_0020608 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension Box of 50" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020886 .

obo:VO_0003413 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML" ;
  rdfs:subClassOf obo:VO_0003408 , obo:VO_0010437 .

obo:VO_0017020 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0016995 , obo:VO_0017497 .

obo:VO_0018858 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0000880 a rdfs:Class ;
  rdfs:label "pCLF4 vaccine" ;
  rdfs:comment "pCLF4 is a Bacillus anthracis vaccine that contains the N-terminal region (amino acids [aa] 10-254) of Bacillus anthracis LF cloned into the pCI expression plasmid." ;
  rdfs:subClassOf obo:VO_0000013 .

obo:VO_0018529 a rdfs:Class ;
  rdfs:label "0.5 ML Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injectable Suspension [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0018528 , obo:VO_0018621 .

obo:VO_0016254 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015918 .

obo:VO_0004660 a rdfs:Class ;
  rdfs:label "rVSV-EBOV vaccine" ;
  rdfs:comment "An Ebola virus vaccine that uses a recombinant vesicular stomatitis virus (rVSV) vector expressing an Ebola filovirus glycoprotein" ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0000161 a rdfs:Class ;
  rdfs:label "Escherichia coli gene" ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0010005 a rdfs:Class ;
  rdfs:label "CpP2 from Crptosporidium parvum" ;
  rdfs:comment "A CpP2 protein that is part of Crptosporidium parvum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010842 .

obo:VO_0003783 a rdfs:Class ;
  rdfs:label "Flucelvax 2015-2016 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003782 .

obo:VO_0020702 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 1.62 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0020700 , obo:VO_0020735 .

obo:VO_0011141 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/turkey/Ireland/1378/1983(H5N8))" ;
  rdfs:comment "All  specific-pathogen-free chickens immunized with (vFP89) expressing the native hemagglutinin (HA) gene from H5N8 A/turkey/ Ireland/1378/83 were clinically protected from HPAI challenge [PubMed: 20521642]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0020111 a rdfs:Class ;
  rdfs:label "L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010446 , obo:VO_0018797 .

obo:NCBITaxon_85007 a rdfs:Class ;
  rdfs:label "Mycobacteriales" ;
  rdfs:subClassOf obo:NCBITaxon_1783272 .

obo:VO_0010171 a rdfs:Class ;
  rdfs:label "hepatitis B vaccine, pediatric or pediatric/adolescent dosage" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010439 .

obo:VO_0010417 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2014-2015" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0018927 a rdfs:Class ;
  rdfs:label "influenza B virus B/Michigan/01/2021 antigen" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:VO_0001036 a rdfs:Class ;
  rdfs:label "Streptococcus gordonii vaccine vector" ;
  rdfs:comment "a bacterial vaccine vector using a live attenuated Streptococcus gordonii vaccine vector." ;
  rdfs:subClassOf obo:VO_0000166 .

obo:VO_0017090 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Repevax] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017089 .

obo:VO_0016972 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 50 LFU/ML / tetanus toxin 10 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017427 .

obo:VO_0001141 a rdfs:Class ;
  rdfs:label "fungal vaccine vector" ;
  rdfs:comment "a recombinant vaccine vector that uses a fungus as the vaccine vector" ;
  rdfs:subClassOf obo:VO_0000599 .

obo:OPL_0000258 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum gamete" ;
  rdfs:comment "A Plasmodium falciparum that is found in midgut of mosquito vector. There are two forms of gametes: micro- and macrogametocytes." ;
  rdfs:subClassOf obo:NCBITaxon_5833 , obo:OPL_0000264 .

obo:VO_0019428 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus capsular oligosaccharide Injectable Suspension [HibTITER]" ;
  rdfs:subClassOf obo:VO_0000659 , obo:VO_0019425 .

obo:VO_0017281 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.013 MG / Bordetella pertussis 0.01 MG / diphtheria toxoid vaccine, inactivated 30 UNT / tetanus toxoid vaccine, inactivated 40 UNT Injection" ;
  rdfs:subClassOf obo:VO_0017230 .

obo:VO_0007194 a rdfs:Class ;
  rdfs:label "Ad CMV I kappaB alpha vaccine" ;
  rdfs:comment "Gene name: GPT" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:DOID_11934 a rdfs:Class ;
  rdfs:label "head and neck cancer"@en ;
  rdfs:comment "An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx."@en ;
  rdfs:subClassOf obo:DOID_0050686 .

obo:VO_0000332 a rdfs:Class ;
  rdfs:label "tertiary vaccination" ;
  rdfs:comment "tertiary vaccination is a vaccination that is performed at the third time in a row." ;
  rdfs:subClassOf obo:VO_0000708 .

obo:VO_0002999 a rdfs:Class ;
  rdfs:label "obsolete WEEV DNA Vaccine encoding 6K-E1 Protein" ;
  rdfs:comment "A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" .

obo:VO_0005417 a rdfs:Class ;
  rdfs:label "Omicron COVID-19 inactivated vaccine by China National Biotec Group Company Limited" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by China National Biotec Group Company Limited" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005201 .

obo:VO_0001580 a rdfs:Class ;
  rdfs:label "Salmonella Choleraesuis Avirulent Live Culture Vaccine (USDA: 19A1.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000768 , obo:VO_0000813 , obo:VO_0001217 .

obo:VO_0018344 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003335 .

obo:VO_0011260 a rdfs:Class ;
  rdfs:label "LACK" ;
  rdfs:comment "Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge.  A truncated portion of the LACK antigen (LACKp24) was able to induce the highest protective effect compared to other constructs.  The DNA vaccine encoding LACK was able to induce partial protection in mice [PubMed: 18951941]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0001155 a rdfs:Class ;
  rdfs:label "shiga toxin-producing E. coli vaccine" ;
  rdfs:comment "An E. coli vaccine against Shiga toxin-producing E. coli (STEC) infections" ;
  rdfs:subClassOf obo:VO_0000041 .

obo:VO_0018063 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 40 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0018062 .

obo:VO_0018808 a rdfs:Class ;
  rdfs:label "yellow fever virus strain 17D-204 live antigen Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010456 .

obo:VO_0018494 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax II] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0018459 .

obo:VO_0018464 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 10" ;
  rdfs:subClassOf obo:VO_0018435 , obo:VO_0018448 .

obo:VO_0007448 a rdfs:Class ;
  rdfs:label "human papillomavirus  DNA plasmids therapeutic vaccine VGX-3100" ;
  rdfs:comment "A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus (HPV) subtypes 16 and 18, respectively, with potential immunostimulating and antineoplastic activities. Administered via intramuscular electroporation, HPV DNA plasmids therapeutic vaccine VGX-3100 expresses E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against cervical cancer cells expressing E6 and E7 proteins, resulting in tumor cell lysis. HPV type 16 and HPV type 18 are the most common HPV types involved in cervical carcinogenesis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0000667 , obo:VO_0007656 , obo:VO_0007660 .

obo:VO_0018398 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.001 MG" ;
  rdfs:subClassOf obo:VO_0003212 .

obo:OPL_0000164 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi trypomastigote" ;
  rdfs:comment "A Trypanosoma cruzi that is found in the bloodstream of infected mammals. It is a non-dividing form that is infectious for its insect vector." ;
  rdfs:subClassOf obo:NCBITaxon_5693 .

obo:VO_0019395 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.08 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 12 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017808 , obo:VO_0018769 .

obo:VO_0011239 a rdfs:Class ;
  rdfs:label "UL44 from Pseudorabies virus" ;
  rdfs:comment "A trial vaccine containing pseudorabies virus (PRV) glycoprotein gC as the main component showed excellent protection against virulent virus infection in pigs [PubMed: 9300361]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010800 .

obo:VO_0018028 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 2000000 CELLS/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 200000 CELLS/ML / poliovirus vaccine inactivated, type 3 (Saukett) 600000 CELLS/ML [Polio Sabin-S]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010447 , obo:VO_0018046 .

obo:VO_0019553 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Afluria Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0019544 , obo:VO_0020304 .

obo:VO_0007607 a rdfs:Class ;
  rdfs:label "gp100 vaccine" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0005387 a rdfs:Class ;
  rdfs:label "3M-052-Alum vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0004654 a rdfs:Class ;
  rdfs:label "BV-H5/H7/H9 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0010485 a rdfs:Class ;
  rdfs:label "licensed human Junin virus vaccine" ;
  rdfs:comment "Junin virus vaccine that is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0006027 .

obo:VO_0002931 a rdfs:Class ;
  rdfs:label "obsolete Shigella sonnei virG/senA/senB/msbB2 mutant vaccine" ;
  rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" .

obo:VO_0019219 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:BFO_0000147 a rdfs:Class ;
  rdfs:label "zero-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:VO_0019188 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019659 .

obo:VO_0017068 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Tetamun]" ;
  rdfs:subClassOf obo:VO_0017067 , obo:VO_0017545 .

obo:VO_0017817 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0010437 , obo:VO_0015063 .

obo:VO_0003562 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 9V vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003561 .

obo:VO_0017308 a rdfs:Class ;
  rdfs:label "Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 4 LFU/ML / Pertussis Vaccine 0.021 MG/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML [Adacel]" ;
  rdfs:subClassOf obo:VO_0000005 , obo:VO_0018784 .

obo:VO_0003007 a rdfs:Class ;
  rdfs:label "Plasmodium FabB/FabF mutant vaccine" ;
  rdfs:comment "A genetically attenuated parasite (GAP) with a mutation in the FabB/FabF gene is attenuated in mice by arresting in the late liver stage. It also conferred complete protection in mice from challenge with wild type Plasmodium" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0001294 a rdfs:Class ;
  rdfs:label "GM-CSF vaccine adjuvant" ;
  rdfs:comment "A cytokine vaccine adjuvant that includes GM-CSF." ;
  rdfs:subClassOf obo:VO_0001353 .

obo:VO_0020035 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe [Fluvirin 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020028 , obo:VO_0020471 .

obo:VO_0004366 a rdfs:Class ;
  rdfs:label "Herpes simplex virus DNA vaccine Delta-gB-2 encoding gB" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012168 .

obo:VO_0017735 a rdfs:Class ;
  rdfs:label "2 ML acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution Box of 5" ;
  rdfs:subClassOf obo:VO_0017731 , obo:VO_0017766 .

obo:VO_0017996 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0018037 .

obo:VO_0020287 a rdfs:Class ;
  rdfs:label "varicella-zoster virus vaccine live (Oka-Merck) strain 29800 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0003279 .

obo:VO_0020214 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.025 MG/ML / SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (BA.4/BA.5) 0.025 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005265 .

obo:VO_0010897 a rdfs:Class ;
  rdfs:label "E2 from Classical swine fever virus" ;
  rdfs:comment """Pigs were subjected to challenge infection with a dose of 1x10(5)TCID(50) (50% tissue culture infective dose) virulent CSFV strain.  At 1 week post challenge infection, all of the yE2-immunized pigs were alive and without symptoms or signs of CSF.  The yeast-expressed E2 protein retains correct immunogenicity and is able to induce a protective immune response against CSFV infection [PubMed: 19625145].

In a seperate study, swine vaccinated with VVR expressing E0 and/or E2 resisted a lethal challenge infection with CSFV. Glycoprotein E0 represents a second determinant for the induction of protective immunity against classical swine fever [PubMed: 7666549].""" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010801 .

obo:VO_0001724 a rdfs:Class ;
  rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.03)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000620 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0005126 a rdfs:Class ;
  rdfs:label "recombinant SARS DNA spike protein vaccine" ;
  rdfs:comment "A recombinant SARS DNA vaccine made from rDNA-expressed ectodomain of the S protein." ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000484 , obo:VO_0012183 .

obo:OPL_0000283 a rdfs:Class ;
  rdfs:label "Plasmodium erythrocytic ring trophozoite" ;
  rdfs:comment "A Plasmodium erythrocytic trophozoite that has a typical 'ring-like' appearance. Ring-form trophozoites of Plasmodium are often thin and delicate, measuring on average 1/5 the diameter of the red blood cell." ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000282 .

obo:VO_0004155 a rdfs:Class ;
  rdfs:label "Pseduorabies Subunit Glycoprotein C vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0000750 .

obo:VO_0015304 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015300 .

obo:VO_0002086 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12P5.40)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002384 , obo:VO_0007748 .

obo:VO_0019673 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0021018 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 200 UNT/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0021013 .

obo:VO_0018570 a rdfs:Class ;
  rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0018761 .

obo:VO_0004531 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii DNA vaccine ROP8-pVAX-1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000994 .

obo:VO_0020378 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Intramuscular Solution [Typhim V]" ;
  rdfs:subClassOf obo:VO_0020361 , obo:VO_0020368 , obo:VO_0020384 .

obo:VO_0000171 a rdfs:Class ;
  rdfs:label "Plasmodium gene" ;
  rdfs:subClassOf obo:VO_0000170 .

obo:NCBITaxon_1549675 a rdfs:Class ;
  rdfs:label "Galloanserae" ;
  rdfs:subClassOf obo:NCBITaxon_8825 .

obo:VO_0007311 a rdfs:Class ;
  rdfs:label "Autologous Ovarian Tumor Cell Lysate-Pulsed Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous, irradiated dendritic cells (DCs) pulsed with ovarian tumor cell lysate containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous ovarian tumor cell lysate-pulsed dendritic cell vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against ovarian tumor cells expressing the patients ovarian tumor cell-specific TAAs, which may result in ovarian tumor cell lysis." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0015644 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B]" ;
  rdfs:subClassOf obo:VO_0003420 , obo:VO_0015545 .

obo:VO_0001520 a rdfs:Class ;
  rdfs:label "Infectious salmon anemia virus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Infectious salmon anemia virus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0004426 a rdfs:Class ;
  rdfs:label "Carcinoma DNA vaccine pVAX/E2A" ;
  rdfs:comment "Gene name: E2A" ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0005353 a rdfs:Class ;
  rdfs:label "UM-3004 vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that includes UM-3004, a small molecule TLR7/8 agonist that can stimulate Th1-biased immune profile." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0015702 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 25" ;
  rdfs:subClassOf obo:VO_0015569 , obo:VO_0015791 .

obo:VO_0003122 a rdfs:Class ;
  rdfs:label "Certiva vaccine" ;
  rdfs:comment "A vaccine against diphtheria, tetanus, and pertussis." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000641 , obo:VO_0000738 .

obo:VO_0007565 a rdfs:Class ;
  rdfs:label "HLA-A2, A3-Restricted FGF-5 Peptides/Montanide ISA-51 Vaccine" ;
  rdfs:comment "A peptide vaccine comprised of synthetic HLA-A2- and HLA-A3-binding peptides, derived from amino acid sequences of fibroblast growth factor-5 (FGF-5), combined with the adjuvant Montanide ISA-51 with potential antineoplastic activity. HLA-A2, A3-restricted FGF-5 peptides contain motifs recognized by the MHC class I molecules HLA-A2 and HLA-A3 and may stimulate a cytotoxic T-cell response against tumor cells that overexpress FGF-5. Montanide ISA-51, a stabilized water-in-oil emulsion adjuvant containing mineral oil with mannide oleate added as a surfactant, non-specifically stimulates cell-mediated immune responses to antigens" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005494 , obo:VO_0007657 .

obo:VO_0010052 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum Pfs230" ;
  rdfs:comment "A Pfs230 protein that is part of Plasmodium falciparum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0001256 a rdfs:Class ;
  rdfs:label "polysaccharide of pathogen organism as vaccine component" ;
  rdfs:subClassOf obo:VO_0000000 .

obo:VO_0007281 a rdfs:Class ;
  rdfs:label "Autologous CT7/MAGE-A3/WT1 mRNA-Electroporated Langerhans-Type Dendritic Cells Vaccine" ;
  rdfs:comment "An autologous tumor cell vaccine containing CD34+ hematopoietic progenitor cell (HPC)-derived Langerhans-type dendritic cells (LCs) electroporated with mRNA encoding the full-length cancer-testis antigens, CT7 and melanoma-associated antigen 3 (MAGE-A3), and the self-differentiation tumor antigen, Wilms tumor 1 (WT1) with potential immunomodulating and antineoplastic activity. The autologous CT7/MAGE-A3/WT1 mRNA-electroporated Langerhans-type dendritic cells are prepared by drawing a blood sample containing the CD34+ HPCs from a cancer patient. The CD34+ HPCs are treated with a combination of cytokines which specifically support LC development, and the LC population is enriched and expanded ex vivo. The cultured LCs are allowed to mature for one day and then electroporated separately with CT7, MAGE-A3 or WT1 mRNA before final maturation. Upon intradermal administration into the patient, the mature LCs may activate cell-mediated immunity and induce both cytotoxic CD8+ T cells and CD4+ helper T cells against cancer cells expressing CT7, MAGE-A3 and WT1 tumor antigens. This may result in the immune-mediated inhibition of tumor cell proliferation, leading to tumor cell death. CT7 and MAGE-A3 are tumor-specific proteins overexpressed in a number of cancers but not in healthy tissues other than testis and placenta. WT1 is a transcription factor important in development and cancer pathogenesis, which is overexpressed in a variety of cancers, including multiple myeloma, leukemia, ovarian cancer, malignant mesothelioma, neural tumors and renal carcinoma." ;
  rdfs:subClassOf obo:VO_0000186 , obo:VO_0000484 , obo:VO_0005492 , obo:VO_0007657 .

obo:DOID_3093 a rdfs:Class ;
  rdfs:label "nervous system cancer"@en ;
  rdfs:comment "An organ system cancer located_in the nervous system that affects the central or peripheral nervous system."@en ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_863 .

obo:VO_0000131 a rdfs:Class ;
  rdfs:label "calcium phosphate vaccine adjuvant" ;
  rdfs:comment "A mineral salt vaccine adjuvant composed of calcium phosphate." ;
  rdfs:subClassOf obo:VO_0000093 .

obo:VO_0020916 a rdfs:Class ;
  rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain Injection [Fluvax]" ;
  rdfs:subClassOf obo:VO_0003216 , obo:VO_0020913 .

obo:VO_0017676 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003384 .

obo:VO_0020992 a rdfs:Class ;
  rdfs:label "Influenza Virus Surface Antigens, strain A / Switzerland / 9715293/2013 H3N2 - Analogue Strain Nib-88 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0020988 .

obo:VO_0015239 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015238 , obo:VO_0015241 .

obo:VO_0000339 a rdfs:Class ;
  rdfs:label "Francisella tularensis vaccine FSC043" ;
  rdfs:comment "A spontaneous mutant of the SCHU S4 strain that protects against virulent F. tularensis infection." ;
  rdfs:subClassOf obo:VO_0000152 .

obo:VO_0015097 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML Prefilled Syringe [Epaxal] Box of 1 by Stada" ;
  rdfs:subClassOf obo:VO_0015096 .

obo:VO_0016611 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0016562 , obo:VO_0016616 .

obo:VO_0019565 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injectable Suspension [Flulaval Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0003773 , obo:VO_0019544 .

obo:VO_0018693 a rdfs:Class ;
  rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 700000 PFU Powder for Oral Suspension" ;
  rdfs:subClassOf obo:VO_0018691 , obo:VO_0018698 .

obo:VO_0003589 a rdfs:Class ;
  rdfs:label "Fluzone 2017-2018 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 , obo:VO_0010433 .

obo:VO_0005130 a rdfs:Class ;
  rdfs:label "VRP-MERS-N vaccine" ;
  rdfs:comment "A MERS recombinant vector made from Venezuelan equine encephalitis replicons bearing epitopes of N protein from MERS. Crosslisted as SARS vaccine (VIOLINID:5754). Efficacy higher intranasally than subcutaneously." ;
  rdfs:subClassOf obo:VO_0004900 .

obo:VO_0001852 a rdfs:Class ;
  rdfs:label "Feline Rhinotracheitis-Calici-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16F1.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002435 , obo:VO_0007748 .

obo:VO_0018557 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1" ;
  rdfs:subClassOf obo:VO_0018556 , obo:VO_0018560 , obo:VO_0018722 .

obo:VO_0011084 a rdfs:Class ;
  rdfs:label "OmpP2" ;
  rdfs:comment "Rabbit antibody prepared against P2 from one strain was cross-reactive with P2 isolated from the other two heterologous strains by Western blot. This antibody passively protected infant rats against type b Haemophilus infection caused by the homologous organism, but not against challenge by a strain with the heterologous 36,500 mol wt P2 protein [PubMed: 6603479]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010772 .

obo:VO_0005455 a rdfs:Class ;
  rdfs:label "licensed human varicella zoster immune globulin  passive vaccine (Investigational New Drug)" ;
  rdfs:subClassOf obo:VO_0005446 .

obo:VO_0017461 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 160 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution [T Polio Adsorbed]" ;
  rdfs:subClassOf obo:VO_0017458 , obo:VO_0017460 .

obo:VO_0004480 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine pCPA" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:VO_0017221 a rdfs:Class ;
  rdfs:label "7.5 ML tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017220 , obo:VO_0017222 , obo:VO_0017473 .

obo:VO_0004936 a rdfs:Class ;
  rdfs:label "human age 4 to 6 years at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004928 .

obo:VO_0005055 a rdfs:Class ;
  rdfs:label "pUSK DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pUSK." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0015171 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 10 by MZG" ;
  rdfs:subClassOf obo:VO_0015164 .

obo:VO_0003766 a rdfs:Class ;
  rdfs:label "FluLaval Quadrivalent 2015-2016 vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003764 .

obo:VO_0020520 a rdfs:Class ;
  rdfs:label "0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML Nasal Spray [Flumist]" ;
  rdfs:subClassOf obo:VO_0020519 , obo:VO_0020951 .

obo:VO_0003061 a rdfs:Class ;
  rdfs:label "Bovine viral diarrhea virus 2 vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Bovine viral diarrhea virus 2 infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003546 .

obo:VO_0011434 a rdfs:Class ;
  rdfs:label "Chlamydophila pneumoniae DNA vaccine encoding FabD" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012173 .

obo:VO_0015684 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [Gen Vax] Box of 10" ;
  rdfs:subClassOf obo:VO_0015565 , obo:VO_0015777 .

obo:VO_0000202 a rdfs:Class ;
  rdfs:label "Hepatitis A virus gene" ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0010763 a rdfs:Class ;
  rdfs:label "Lassa Fever Virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0003948 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0010440 .

obo:VO_0018453 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumopur] Box of 20" ;
  rdfs:subClassOf obo:VO_0018431 , obo:VO_0018437 .

obo:VO_0020952 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 50000000 /ML / influenza B virus antigen 50000000 /ML Nasal Spray [Flumist] Box of 5" ;
  rdfs:subClassOf obo:VO_0020951 , obo:VO_0020953 .

obo:VO_0001152 a rdfs:Class ;
  rdfs:label "enterotoxigenic E. coli vaccine" ;
  rdfs:comment "An E. coli vaccine against enterotoxigenic E. coli infections" ;
  rdfs:subClassOf obo:VO_0000041 .

obo:VO_0016161 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 1 by Merck" ;
  rdfs:subClassOf obo:VO_0016002 .

obo:VO_0015318 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injectable Suspension [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0015315 .

obo:VO_0006109 a rdfs:Class ;
  rdfs:label "nucleic acid vaccine adjuvant" ;
  rdfs:comment "A vaccine adjuvant that is primarily composed of nucleic acid." ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017680 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0002879 a rdfs:Class ;
  rdfs:label "Salmonella Gallinarum crp mutant vaccine" ;
  rdfs:comment "A crp mutant is attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ;
  rdfs:subClassOf obo:VO_0002508 .

obo:VO_0001676 a rdfs:Class ;
  rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.15)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001488 , obo:VO_0007748 .

obo:VO_0017058 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 LFU/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017049 , obo:VO_0017526 .

obo:VO_0017509 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe [Tetanol] Box of 10" ;
  rdfs:subClassOf obo:VO_0017507 , obo:VO_0017514 .

obo:VO_0007033 a rdfs:Class ;
  rdfs:label "PCLUS 6.1-18MN vaccine" ;
  rdfs:comment "A synthetic HIV-1 envelope peptide that was developed for use as a vaccine. Vaccination with PCLUS 6.1-18MN may stimulate the host immune system to mount cytotoxic T lymphocyte (CTL) and T helper cell responses, and induce the production of neutralizing antibodies." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0001108 a rdfs:Class ;
  rdfs:label "ORF virus vaccine vector" ;
  rdfs:comment "a poxvirus vaccine vector that uses an ORF virus which is a parapoxvirus." ;
  rdfs:subClassOf obo:VO_0000447 .

obo:VO_0002240 a rdfs:Class ;
  rdfs:label "Canine Parvovirus Modified Live Virus Vaccine-Leptospira Canicola Icterohaemorrhagiae Bacterin (USDA: 47B1.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002419 , obo:VO_0007748 .

obo:NCBITaxon_10786 a rdfs:Class ;
  rdfs:label "Feline panleukopenia virus" ;
  rdfs:subClassOf obo:NCBITaxon_3052707 .

obo:VO_0000659 a rdfs:Class ;
  rdfs:label "HIBTITER vaccine" ;
  rdfs:subClassOf obo:VO_0000662 .

obo:VO_0003366 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen" ;
  rdfs:subClassOf obo:VO_0003960 .

obo:BFO_0000144 a rdfs:Class ;
  rdfs:label "process profile"@en ;
  rdfs:comment "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:VO_0017330 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / influenza B virus antigen / influenza B virus antigen, Hong Kong 330-2001 / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Act-HIB DTP]" ;
  rdfs:subClassOf obo:VO_0017329 .

obo:VO_0015336 a rdfs:Class ;
  rdfs:label "hepatitis A virus / typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Injectable Suspension [ViATIM]" ;
  rdfs:subClassOf obo:VO_0015323 , obo:VO_0015335 .

obo:VO_0020858 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Fluarix]" ;
  rdfs:subClassOf obo:VO_0020851 , obo:VO_0020891 .

obo:VO_0001733 a rdfs:Class ;
  rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.03)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001019 , obo:VO_0007748 .

obo:VO_0001881 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4059.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002334 .

obo:VO_0004665 a rdfs:Class ;
  rdfs:label "rMVA-CCHF vaccine" ;
  rdfs:subClassOf obo:VO_0001365 .

obo:NCBITaxon_5759 a rdfs:Class ;
  rdfs:label "Entamoeba histolytica" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:VO_0003611 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0004914 , obo:VO_0010417 .

obo:VO_0016622 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 10" ;
  rdfs:subClassOf obo:VO_0016601 , obo:VO_0016612 , obo:VO_0016629 .

obo:VO_0015723 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Gemvites] Box of 3" ;
  rdfs:subClassOf obo:VO_0015573 , obo:VO_0015799 .

obo:VO_0018333 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabivac] Box of 1 by Boehringer Ingelheim" ;
  rdfs:subClassOf obo:VO_0018320 .

obo:VO_0003152 a rdfs:Class ;
  rdfs:label "HEPLISAV-B vaccine" ;
  rdfs:comment "A Hepatitis B surface antigen viral vaccine that utilizes a cytidine-phosphate-guanosine oligodeoxynucleotide (CpGODN) 1018, as an adjuvant." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000484 , obo:VO_0000644 , obo:VO_0010439 .

obo:VO_0020531 a rdfs:Class ;
  rdfs:label "0.5 ML A/Hong Kong/4801/2014 (H3n2) - Like Virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain 0.03 MG/ML Injectable Suspension [INFLUVAC]" ;
  rdfs:subClassOf obo:VO_0020530 , obo:VO_0020684 .

obo:VO_0019340 a rdfs:Class ;
  rdfs:label "0.5 ML Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML Prefilled Syringe [Menactra]" ;
  rdfs:subClassOf obo:VO_0000071 , obo:VO_0000561 .

obo:VO_0007508 a rdfs:Class ;
  rdfs:label "Melan-A VLP vaccine" ;
  rdfs:comment "A vaccine consisting of the melanocyte differentiation antigen Melan A (also called MART-1) encapsulated in noninfectious virus-like particles (VLP) with potential immunostimulating and antineoplastic activities. Upon administration, Melan-A VLP vaccine may activate the immune system to exert a specific cytotoxic T lymphocyte (CTL) response against cancer cells expressing the Melan A antigen, resulting in tumor cell lysis. Melan A is an antigen that is upregulated in most melanomas. VLP stimulates the immune system and promotes the CTL response." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0015022 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Tenivac]" ;
  rdfs:subClassOf obo:VO_0015025 .

obo:NCBITaxon_35324 a rdfs:Class ;
  rdfs:label "unclassified Orthomyxoviridae" ;
  rdfs:subClassOf obo:NCBITaxon_11308 .

obo:VO_0000987 a rdfs:Class ;
  rdfs:label "bovine herpesvirus 1 vaccine" ;
  rdfs:comment "Viral vaccine that is used to protect against Bovine herpesvirus 1 infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001466 , obo:VO_0003537 .

obo:VO_0000756 a rdfs:Class ;
  rdfs:label "acellular vaccine" ;
  rdfs:comment "A subunit vaccine that is produced by using only the antigenic part of the disease causing organism. It often requires a \"booster\" every few years to maintain their effectiveness." ;
  rdfs:subClassOf obo:VO_0000534 .

obo:VO_0012362 a rdfs:Class ;
  rdfs:label "OprI" ;
  rdfs:comment "Recombinant OprI protein was used to immunize mice, and was found to be protective against a challenge with a four- to fivefold 50% lethal dose of P. aeruginosa [PubMed: 2114360]." ;
  rdfs:subClassOf obo:VO_0012370 .

obo:VO_0005412 a rdfs:Class ;
  rdfs:label "V-01-351/V-01D Bivalence Vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Livzon Pharmaceutical Group Inc." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005269 .

obo:VO_0011444 a rdfs:Class ;
  rdfs:label "E. coli IreA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0019520 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.003 MG/ML" ;
  rdfs:subClassOf obo:VO_0003150 .

obo:VO_0011484 a rdfs:Class ;
  rdfs:label "obsolete Td Polio Adsorbed" ;
  rdfs:comment "This term is obsolete since there is another term with the same name." .

obo:VO_0004478 a rdfs:Class ;
  rdfs:label "Bacillus anthracis DNA vaccine pTPA-P" ;
  rdfs:subClassOf obo:VO_0000013 , obo:VO_0000032 .

obo:NCBITaxon_483179 a rdfs:Class ;
  rdfs:label "Brucella canis ATCC 23365" ;
  rdfs:subClassOf obo:NCBITaxon_36855 .

obo:VO_0001025 a rdfs:Class ;
  rdfs:label "vesicular stomatitis virus vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses a vesicular stomatitis virus (VSV) as the vector." ;
  rdfs:subClassOf obo:VO_0001121 .

obo:VO_0015933 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Gen Vax] Box of 3" ;
  rdfs:subClassOf obo:VO_0015635 , obo:VO_0016038 .

obo:VO_0002961 a rdfs:Class ;
  rdfs:label "Feline infectiour peritonitis virus 3abc mutant vaccine" ;
  rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ;
  rdfs:subClassOf obo:VO_0001504 .

obo:VO_0015987 a rdfs:Class ;
  rdfs:label "10 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1" ;
  rdfs:subClassOf obo:VO_0015652 , obo:VO_0015711 , obo:VO_0016064 .

obo:VO_0002706 a rdfs:Class ;
  rdfs:label "gI from Equid herpesvirus" ;
  rdfs:comment "A glycoprotein I mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001431 .

obo:VO_0011228 a rdfs:Class ;
  rdfs:label "HEP17" ;
  rdfs:comment "Immunization of mice with subunit vaccines based on the Plasmodium yoelii 17kDa hepatocyte erythrocyte protein (PyHEP17), orthologue of Plasmodium falciparum exported protein 1 (PfExp1), induces antigen-specific immune responses and protects against sporozoite challenge [PubMed: 17303242]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015474 .

obo:VO_0017702 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Repevax] Box of 5 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017701 .

obo:VO_0006090 a rdfs:Class ;
  rdfs:label "tetravalent dengue fever vaccine" ;
  rdfs:subClassOf obo:VO_0000725 .

obo:VO_0017806 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated Injectable Solution" ;
  rdfs:subClassOf obo:VO_0003196 , obo:VO_0017808 .

obo:VO_0003741 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2016-2017 Formula Influenza Virus Vaccine Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003739 .

obo:VO_0011130 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Indonesia/CDC669/2006(H5N1))" ;
  rdfs:comment "Viral challenge studies showed that live BacHA derived from Influenza A virus (A/Indonesia/CDC669/2006(H5N1)) was able to provide 100% protection against 5 50% mouse lethal doses (MLD(50)) of homologous (clade 2.1) and heterologous (clade 1) H5N1 [PubMed: 20071572]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0001901 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine (USDA: 1155.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0002345 .

obo:VO_0004928 a rdfs:Class ;
  rdfs:label "human child age range at vaccination" ;
  rdfs:comment "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ;
  rdfs:subClassOf obo:VO_0004927 .

obo:VO_0005428 a rdfs:Class ;
  rdfs:label "brain cancer vaccine" ;
  rdfs:comment "A cancer vaccine that is used against brain canceer." ;
  rdfs:subClassOf obo:VO_0000177 .

obo:VO_0015514 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Lt Grk]" ;
  rdfs:subClassOf obo:VO_0003256 .

obo:VO_0002007 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45B9.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002370 .

obo:VO_0017999 a rdfs:Class ;
  rdfs:label "0.5 ML poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML Injection by Saudi" ;
  rdfs:subClassOf obo:VO_0017996 .

obo:VO_0017587 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 8 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017586 , obo:VO_0017588 .

obo:VO_0017139 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Solution [Tetanol] Box of 20 by Novartis" ;
  rdfs:subClassOf obo:VO_0017138 .

obo:VO_0021007 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 19400 PFU" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:VO_0004719 a rdfs:Class ;
  rdfs:label "CVB4/p24(73(3)) vaccine" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0001245 a rdfs:Class ;
  rdfs:label "Synflorix vaccine" ;
  rdfs:comment "SYNFLORIX is indicated for active immunization of infants and children from 6 weeks up to 5 years of age against Streptococcus pneumoniae serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F and 23F and invasive disease caused by these serotypes (including sepsis, meningitis, bacteraemic pneumonia, pleural empyema and bacteraemia)." ;
  rdfs:subClassOf obo:VO_0000675 , obo:VO_0001214 , obo:VO_0010453 .

obo:VO_0018624 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0018640 , obo:VO_0018799 .

obo:VO_0018185 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps virus / Rubella virus / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018184 .

obo:VO_0010351 a rdfs:Class ;
  rdfs:label "JYNNEOS vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000641 , obo:VO_0001220 , obo:VO_0003060 , obo:VO_0010452 .

obo:VO_0017969 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 0.03 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Meningitec]" ;
  rdfs:subClassOf obo:VO_0017946 .

obo:VO_0020018 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003499 , obo:VO_0004914 , obo:VO_0010415 .

obo:NCBITaxon_635 a rdfs:Class ;
  rdfs:label "Edwardsiella <enterobacteria>" ;
  rdfs:subClassOf obo:NCBITaxon_91347 .

obo:VO_0010756 a rdfs:Class ;
  rdfs:label "fungus protein" ;
  rdfs:comment "a protein from fungus" ;
  rdfs:subClassOf obo:PR_000000001 .

obo:VO_0020020 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Injectable Suspension [Afluria 2010-2011 Formula]" ;
  rdfs:subClassOf obo:VO_0020019 , obo:VO_0020298 .

obo:VO_0016886 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 10 UNT/ML Injectable Solution Box of 10 by Novartis" ;
  rdfs:subClassOf obo:VO_0016878 .

obo:NCBITaxon_5855 a rdfs:Class ;
  rdfs:label "Plasmodium vivax" ;
  rdfs:subClassOf obo:NCBITaxon_418103 .

obo:VO_0001740 a rdfs:Class ;
  rdfs:label "Flavobacterium Columnare Avirulent Live Culture Vaccine (USDA: 17F1.00)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000637 , obo:VO_0000645 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0001153 a rdfs:Class ;
  rdfs:label "Androvax vaccine" ;
  rdfs:subClassOf obo:VO_0000372 , obo:VO_0000455 , obo:VO_0000503 .

obo:VO_0018128 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000737 .

obo:VO_0010939 a rdfs:Class ;
  rdfs:label "Omp31" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0001228 a rdfs:Class ;
  rdfs:label "Coxsackievirus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Coxsackievirus" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003547 .

obo:VO_0011304 a rdfs:Class ;
  rdfs:label "MOMP from C. psittaci 6BC" ;
  rdfs:comment "Transgenic rice immunization expressing the Chlamydophila psittaci (Cp. psittaci) antigen (MOMP) fused to the B subunit of Escherichia coli heat-labile enterotoxin (LTB) induced partial protection (53.3%) against a lethal challenge with the highly virulent Cp. psittaci 6BC strain in a BALB/c mouse model [PubMed: 19146896]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010839 .

obo:VO_0015475 a rdfs:Class ;
  rdfs:label "Plasmodium berghei protein" ;
  rdfs:subClassOf obo:VO_0010771 .

obo:VO_0012175 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei vaccine" ;
  rdfs:comment "A vaccine that protects against Burkholderia pseudomallei." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003532 .

obo:VO_0001836 a rdfs:Class ;
  rdfs:label "Mink Distemper-Enteritis Modified Live Virus & Killed Virus Vaccine-Clostridium botulinum Type C Bacterin-Toxoid (USDA: 4929.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001021 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0002449 , obo:VO_0007748 , obo:VO_0010475 .

obo:VO_0019854 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Washington/19/2020 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Darwin/7/2019 antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML Injectable Suspension [Flucelvax Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020334 .

obo:VO_0011143 a rdfs:Class ;
  rdfs:label "HA from Influenza A virus (A/Hatay/2004/(H5N1))" ;
  rdfs:comment "A neutralizing monoclonal antibody (mAb) 9F4 against the hemagglutinin (HA) of the influenza A/chicken/hatay/2004 H5N1 virus was generated.   MAb 9F4 was found to be protective, both prophylactically and therapeutically, against lethal viral challenge of mice [PubMed: 20519402]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010782 .

obo:VO_0010119 a rdfs:Class ;
  rdfs:label "Toxoplasma gondii SAG2" ;
  rdfs:comment "A SAG2 protein that is part of Toxoplasma gondii" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010826 .

obo:VO_0007146 a rdfs:Class ;
  rdfs:label "Prostate Cancer Vaccine ONY-P1" ;
  rdfs:comment "A cell-based vaccine derived from prostate cancer with potential immunopotentiating and antineoplastic activities. Prostate cancer vaccine ONY-P1 is derived from three irradiated allogeneic prostate cancer cell lines that represent different stages of prostate cancer and express a broad range of prostate and prostate cancer antigens. Upon administration, this vaccine may stimulate a host immune response against prostate cancer cells; in the vaccination schedule, the first two vaccinations are co-administered with bacillus Calmette-Guerin (BCG) as an adjuvant." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0017270 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.025 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Covaxis]" ;
  rdfs:subClassOf obo:VO_0017228 , obo:VO_0017269 .

obo:VO_0018283 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018268 , obo:VO_0018270 .

obo:VO_0000196 a rdfs:Class ;
  rdfs:label "recombinant vector vaccine preparation" ;
  rdfs:comment "A vaccine preparation that results in the generation of a recombinant vector vaccine" ;
  rdfs:subClassOf obo:VO_0000590 .

obo:VO_0005239 a rdfs:Class ;
  rdfs:label "FAKHRAVAC vaccine" ;
  rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Organization of Defensive Innovation and Research in Iran" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005266 .

obo:VO_0000783 a rdfs:Class ;
  rdfs:label "VRP expressing VP35 vaccine" ;
  rdfs:comment "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP35 protein." ;
  rdfs:subClassOf obo:VO_0000726 .

obo:VO_0004746 a rdfs:Class ;
  rdfs:label "rFPV-H5AI-L2 vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0016988 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0016987 , obo:VO_0017477 .

obo:VO_0005048 a rdfs:Class ;
  rdfs:label "pcDNA DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pcDNA." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019279 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Wisconsin/588/2019 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020326 .

obo:VO_0000489 a rdfs:Class ;
  rdfs:label "obsolete licensed human vaccine role" ;
  rdfs:comment "A licensed vaccine role that is bears in a licensed human vaccine." .

obo:VO_0016832 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 150 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016760 .

obo:VO_0018568 a rdfs:Class ;
  rdfs:label "0.5 ML Salmonella Typhi Inactivated Antigen 0.05 MG/ML Intramuscular Solution [Typherix]" ;
  rdfs:subClassOf obo:VO_0018567 , obo:VO_0018731 .

obo:VO_0000156 a rdfs:Class ;
  rdfs:label "viral gene" ;
  rdfs:subClassOf obo:OGG_0000000002 .

obo:VO_0010796 a rdfs:Class ;
  rdfs:label "Yersinia pseudotuberculosis protein" ;
  rdfs:subClassOf obo:VO_0010753 .

obo:VO_0010438 a rdfs:Class ;
  rdfs:label "licensed human hepatitis A virus vaccine" ;
  rdfs:comment "Hepatitis A virus vaccine with license for human use." ;
  rdfs:subClassOf obo:VO_0000635 , obo:VO_0000646 .

obo:VO_0017069 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Tetamun] Box of 10" ;
  rdfs:subClassOf obo:VO_0017068 , obo:VO_0017072 , obo:VO_0017546 .

obo:VO_0003563 a rdfs:Class ;
  rdfs:label "Pneumovax 23 Injectable Product" ;
  rdfs:subClassOf obo:VO_0000088 .

obo:VO_0000974 a rdfs:Class ;
  rdfs:label "inactivated E. coli vaccine" ;
  rdfs:subClassOf obo:VO_0000041 , obo:VO_0001214 .

obo:VO_0016500 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B] Box of 3 by Axicorp" ;
  rdfs:subClassOf obo:VO_0015980 .

obo:VO_0019285 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), inactivated 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019875 .

obo:VO_0015554 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0003423 , obo:VO_0015525 .

obo:VO_0011366 a rdfs:Class ;
  rdfs:label "cancer subunit NY-ESO-1 protein vaccine" ;
  rdfs:comment "Gene name: CTAG1B" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0004265 a rdfs:Class ;
  rdfs:label "pneumococcal polysaccharide conjugate vaccine serotype 1 (PNC-1)" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0003284 .

obo:VO_0003450 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010306 , obo:VO_0010415 .

obo:VO_0005448 a rdfs:Class ;
  rdfs:label "licensed human respiratory syncytial virus immune globulin passive vaccine, intravenous" ;
  rdfs:subClassOf obo:VO_0005445 .

obo:VO_0000556 a rdfs:Class ;
  rdfs:label "multivalent vaccine" ;
  rdfs:comment "a vaccine that is designed to immunize against two or more strains of the same microorganism, or against two or more microorganisms." ;
  rdfs:subClassOf obo:VO_0000001 .

obo:VO_0015228 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Prefilled Syringe Box of 10" ;
  rdfs:subClassOf obo:VO_0015216 , obo:VO_0015311 .

obo:VO_0003517 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0019662 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/34/2019 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:OPL_0000409 a rdfs:Class ;
  rdfs:label "Plasmodium knowlesi merozoite stage" ;
  rdfs:comment "A merozoite stage in the Plasmodium knowlesi." ;
  rdfs:subClassOf obo:OPL_0000036 , obo:OPL_0000292 , obo:OPL_0000417 .

obo:VO_0002342 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Leptospira Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002336 , obo:VO_0002338 .

obo:VO_0016115 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension [HBvaxPRO] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015872 .

obo:VO_0016432 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Eurim-Pharm" ;
  rdfs:subClassOf obo:VO_0015973 .

obo:VO_0020847 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen 0.03 MG/ML [Preflucel]" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0018137 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML / Mumps Vaccine 35000 PFU/ML / Rubella virus 1400 PFU/ML / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018242 .

obo:VO_0010830 a rdfs:Class ;
  rdfs:label "Sarcocystis neurona protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0007038 a rdfs:Class ;
  rdfs:label "recombinant Saccharomyces Cerevisia-CEA(610D)-expressing vaccine GI-6207" ;
  rdfs:comment "A whole, heat-killed, recombinant Saccharomyces cerevisiae yeast-based vaccine genetically altered to express the carcinoembryonic antigen (CEA) peptide 610D with potential immunostimulating and antineoplastic activities. Upon administration, recombinant Saccharomyces cerevisia-CEA(610D) vaccine GI-6207 may stimulate a host cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells, which may result in tumor cell lysis. CEA, a tumor associated antigen, is overexpressed on a wide variety of human cancer cells including colorectal, gastric, lung, breast and pancreatic cancer cells. CEA 610D encodes for 9 amino acids (605-613) in which aspartate is substituted for asparagine at position 610 (610D) in order to strengthen the induction of the CTL response against CEA-expressing tumor cells." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:OPL_0000311 a rdfs:Class ;
  rdfs:label "Vertebrate erythrocyte" ;
  rdfs:comment "An erythrocyte that is a part of or originated from a vertebrate." ;
  rdfs:subClassOf obo:CL_0000232 .

obo:VO_0017732 a rdfs:Class ;
  rdfs:label "2 ML acellular pertussis vaccine, inactivated 160 MG/ML Injectable Solution [Tussoglobin]" ;
  rdfs:subClassOf obo:VO_0017731 , obo:VO_0017763 .

obo:VO_0000251 a rdfs:Class ;
  rdfs:label "pgp.LAMP-1 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pgp.LAMP-1.  This plasmid has a CMV promoter and contains the human lysosomal-associated membrane protein-1 signal sequence." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0011214 a rdfs:Class ;
  rdfs:label "Fnz" ;
  rdfs:comment "Parts of the three recombinant proteins (FNZ (cell surface-bound fibronectin binding protein), SFS (secreted fibronectin binding protein), and EAG (alpha2-macroglobulin, albumin, and immunoglobulin G [IgG] binding protein)) were used to immunize mice, either subcutaneously or intranasally, prior to nasal challenge with S. equi subsp. equi. The adjuvant used was EtxB, a recombinant form of the B subunit of Escherichia coli heat-labile enterotoxin. It was shown that nasal colonization of S. equi subsp. equi and weight loss due to infection were significantly reduced after vaccination compared with a mock-vaccinated control group. This effect was more pronounced after intranasal vaccination than after subcutaneous vaccination; nearly complete eradication of nasal colonization was obtained after intranasal vaccination (P < 0.001) [PubMed: 15155624]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010816 .

obo:VO_0010261 a rdfs:Class ;
  rdfs:label "vaccine study design" ;
  rdfs:comment "A study design that is about a vaccine study." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:VO_0005401 a rdfs:Class ;
  rdfs:label "RH109 vaccine" ;
  rdfs:comment "A SARS-CoV-2 RNA vaccine by Wuhan Recogen Biotechnology Co., Ltd." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005198 .

obo:VO_0002857 a rdfs:Class ;
  rdfs:label "Mycoplasma gallisepticum lpd mutant vaccine" ;
  rdfs:comment "An lpd mutant is highly attenuated in chickens and induces significant protection from challenge with wild type M. gallisepticum" ;
  rdfs:subClassOf obo:VO_0000949 , obo:VO_0001077 .

obo:VO_0019296 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Flucelvax 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019290 , obo:VO_0020330 .

obo:VO_0019629 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone 2019-2020]" ;
  rdfs:subClassOf obo:VO_0019601 , obo:VO_0020483 .

obo:IAO_0020000 a rdfs:Class ;
  rdfs:label "identifier"@en ;
  rdfs:comment "An information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:DOID_5520 a rdfs:Class ;
  rdfs:label "head and neck squamous cell carcinoma"@en ;
  rdfs:comment "A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck."@en ;
  rdfs:subClassOf obo:DOID_1542 .

obo:VO_0017940 a rdfs:Class ;
  rdfs:label "0.6 ML Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML Injectable Suspension [Menjugate]" ;
  rdfs:subClassOf obo:VO_0017905 .

obo:VO_0015961 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015729 , obo:VO_0015735 , obo:VO_0016045 .

obo:VO_0017822 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide 0.015 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010323 , obo:VO_0010437 .

obo:NCBITaxon_11266 a rdfs:Class ;
  rdfs:label "Filoviridae" ;
  rdfs:subClassOf obo:NCBITaxon_11157 .

obo:VO_0003752 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2018-2019 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003751 .

obo:VO_0016752 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] Box of 25" ;
  rdfs:subClassOf obo:VO_0016714 , obo:VO_0016775 .

obo:VO_0004587 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus DNA vaccine pCJ-3/E encoding E" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000665 .

obo:OPL_0000190 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum hepatic schizont" ;
  rdfs:comment "A Plasmodium falciparum schizont that is found in infected hepatocytes (i.e., liver cells) of a human host." ;
  rdfs:subClassOf obo:OPL_0000060 , obo:OPL_0000277 .

obo:VO_0019752 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/9/2021 (H3N2) antigen 0.0857 MG/ML / influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.0857 MG/ML / influenza B virus B/Michigan/01/2021 antigen 0.0857 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.0857 MG/ML [Fluzone Quadrivalent 2023 Southern Hemisphere]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020496 .

obo:VO_0005511 a rdfs:Class ;
  rdfs:label "EVAX-S vaccine adjuvant" ;
  rdfs:comment "Squalene oil-in-water emulsion vaccine adjuvant made by EVAX Inc., which targets to induce a mixed Th1/Th2 response." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0020233 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain 100000000 UNT/ML Injectable Suspension [Dryvax]" ;
  rdfs:subClassOf obo:VO_0020232 .

obo:OPL_0000275 a rdfs:Class ;
  rdfs:label "Plasmodium schizont" ;
  rdfs:comment "A Plasmodium that is a form divides through schizogony. Depending on its location, it is either called hepatic or erythrocytic schizont. The schizont is a dividing stage with 2 or more nuclei." ;
  rdfs:subClassOf obo:NCBITaxon_5820 .

obo:VO_0001665 a rdfs:Class ;
  rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.56)" ;
  rdfs:subClassOf obo:VO_0000367 , obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000906 , obo:VO_0007748 .

obo:VO_0011067 a rdfs:Class ;
  rdfs:label "GX3262" ;
  rdfs:comment "A cDNA clone derived from sporulated oocysts of Eimeria tenella and encoding the expression product GX3262 was identified using a monoclonal antibody raised against Eimeria acervulina sporozoites.  After challenge with an experimental E. tenella infection, the greatest degree of protection in immunized broiler chickens was seen after only a single immunization of 2-day-old birds with a live recombinant E. coli preparation [PubMed: 2659532]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010823 .

obo:VO_0015129 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe [Epaxal] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015128 .

obo:VO_0010222 a rdfs:Class ;
  rdfs:label "typhoid Vi capsular polysaccharide vaccine" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003443 , obo:VO_0010451 .

obo:VO_0000001 a rdfs:Class ;
  rdfs:label "vaccine" ;
  rdfs:comment "Material entity that is manufactured to realize the vaccine function." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:VO_0015594 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0003109 a rdfs:Class ;
  rdfs:label "Meruvax I vaccine" ;
  rdfs:comment "HPV77/DE5 strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0010450 .

obo:VO_0007372 a rdfs:Class ;
  rdfs:label "dendritic cell-MART-1 Peptide vaccine" ;
  rdfs:comment "A cancer vaccine consisting of dendritic cells harvested from a patient with cancer and pulsed or transduced with a peptide fragment of MART-1 (melanoma antigen recognized by T-cells), an antigen expressed by melanoma cells. When the altered dendritic cells are returned to the patient, they stimulate the host immune system to mount a cytotoxic T-lymphocyte immune response against tumor cells expressing MART-1." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0020319 a rdfs:Class ;
  rdfs:label "Fluarix Quad 2014-2015 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0000983 , obo:VO_0010417 .

obo:VO_0003050 a rdfs:Class ;
  rdfs:label "vaccine conjugate role" ;
  rdfs:comment "A role inheres in a material eneitity that union itself chemically with a relative weak vaccine antigen to form a new whole that can create an effective miinuogen. The " ;
  rdfs:subClassOf obo:VO_0000617 .

obo:NCBITaxon_5867 a rdfs:Class ;
  rdfs:label "Babesia canis" ;
  rdfs:subClassOf obo:NCBITaxon_5864 .

obo:VO_0007224 a rdfs:Class ;
  rdfs:label "Allogeneic GM-CSF-Secreting Breast Cancer Vaccine" ;
  rdfs:comment "An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon vaccination, the genetically modified cells secrete GM-CSF, thereby potentiating a tumor-specific T cell response against breast cancer cell-asociated antigens.A vaccine that is being studied as a way to help the body's immune system kill breast cancer cells. To make the vaccine, the GM-CSF gene is put into breast cancer cells in the laboratory. The cells are then treated with radiation to stop them from growing and injected into the same or a different patient. The GM-CSF protein made by the changed breast cancer cells may help the immune system kill breast cancer cells in the body." ;
  rdfs:subClassOf obo:VO_0005484 , obo:VO_0007657 , obo:VO_0007660 .

obo:VO_0015092 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe [Vaqta] Box of 1 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015089 .

obo:VO_0015783 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015596 .

obo:VO_0016892 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.01 MG/ML / diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0017264 .

obo:VO_0020966 a rdfs:Class ;
  rdfs:label "Influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.00752 MG/ML" ;
  rdfs:subClassOf obo:VO_0003521 .

obo:VO_0002733 a rdfs:Class ;
  rdfs:label "glycoprotein E from Pseudorabies virus" ;
  rdfs:comment "A glycoprotein E mutant, in combination with UL23 and glycoprotein G mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001442 .

obo:VO_0004891 a rdfs:Class ;
  rdfs:label "CN54gp140 + GLA vaccine" ;
  rdfs:comment "A recombinant uncleaved clade C HIV-1 envelope gp140 protein (CN54gp140)" ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0007093 a rdfs:Class ;
  rdfs:label "NA17.A2 peptide vaccine" ;
  rdfs:comment "A peptide cancer vaccine comprised of human leukocyte antigen HLA-A2-restricted peptide derived from a metastatic melanoma cell line of patient NA17, with potential immunomodulating and antineoplastic activity. NA17. A2 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumors that express this antigen, which may result in a reduction in tumor size. This NA17 specific antigen, encoded by an intron sequence of N-acetylglucosaminyltransferase V (GnT-V) gene, is expressed in about 50% of melanomas." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0003927 a rdfs:Class ;
  rdfs:label "Fluad 2017-2018 vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003926 .

obo:VO_0002173 a rdfs:Class ;
  rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1791.14)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001018 , obo:VO_0002457 , obo:VO_0007748 .

obo:VO_0002654 a rdfs:Class ;
  rdfs:label "poxA from Salmonella Typhimurium" ;
  rdfs:comment "A poxA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0002818 a rdfs:Class ;
  rdfs:label "Brucella abortus pgk mutant vaccine" ;
  rdfs:comment "A pgk mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus" ;
  rdfs:subClassOf obo:VO_0001134 .

obo:VO_0003994 a rdfs:Class ;
  rdfs:label "INFANRIX vaccine 0.5 ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003993 .

obo:VO_0001912 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.23)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000813 , obo:VO_0001220 , obo:VO_0002345 .

obo:VO_0000767 a rdfs:Class ;
  rdfs:label "Rickettsial vaccine" ;
  rdfs:comment "Vaccine that protects against Rickettsia infection. Typhus is any of several similar diseases caused by Rickettsia bacteria. So Rickettsial vaccine is also called typhus vaccine. " ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003550 .

obo:VO_0007499 a rdfs:Class ;
  rdfs:label "MAGE-3.A1 peptide vaccine" ;
  rdfs:comment "A synthetic peptide cancer vaccine consisting of human leukocyte antigen HLA-A1-restricted peptide derived from human melanoma antigen 3 (MAGE-3) with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-3.A1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-3, resulting in tumor cell lysis. MAGE-3, a tumor-associated antigen (TAA), is overexpressed by a variety of cancer cell types." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0001471 a rdfs:Class ;
  rdfs:label "gray wolf vaccine" ;
  rdfs:comment "Vaccine that used for immunizing gray wolf." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0001464 .

obo:VO_0000485 a rdfs:Class ;
  rdfs:label "E. coli subunit vaccine using CO393" ;
  rdfs:subClassOf obo:VO_0000628 .

obo:VO_0017754 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.008 MG" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0003196 .

obo:VO_0000272 a rdfs:Class ;
  rdfs:label "pIRES2 DsRed2 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0019485 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.265 MG/ML / hepatitis B surface antigen vaccine 0.01 MG/ML Injection" ;
  rdfs:subClassOf obo:VO_0019481 .

obo:NCBITaxon_9986 a rdfs:Class ;
  rdfs:label "Oryctolagus cuniculus" ;
  rdfs:subClassOf obo:NCBITaxon_314147 .

obo:VO_0017988 a rdfs:Class ;
  rdfs:label "0.5 ML poliomyelitis virus type 1 brunhilde 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution [Poliovaccine Ssi]" ;
  rdfs:subClassOf obo:VO_0017987 , obo:VO_0018013 .

obo:VO_0016994 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 12.5 LFU/ML Injectable Suspension by Statens Serum Institut" ;
  rdfs:subClassOf obo:VO_0016987 .

obo:VO_0011343 a rdfs:Class ;
  rdfs:label "GLURP" ;
  rdfs:comment "Some of the S. sciureus monkeys immunized with MSP-3(212-380)-AS02 or GLURP(27-500)-alum were able to fully or partially control parasitaemia upon an experimental P. falciparum [Falciparum Uganda Palo Alto (FUP-SP) strain] blood-stage infection, and this protection was related to the prechallenge antibody titres induced. The data are indicative that MSP-3 and GLURP can induce protective immunity against an experimental P. falciparum infection using adjuvants that are acceptable for human use and this should trigger further studies with those new antigens [PubMed: 15049780]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015471 .

obo:VO_0011089 a rdfs:Class ;
  rdfs:label "N protein [Topografov virus]" ;
  rdfs:comment "To investigate the ability of recombinant N (rN, nucleocapsid proteins) from different hantaviruses to elicit cross-protection, we immunized bank voles with rN from Puumala (PUUV), Topografov (TOPV), Andes (ANDV), and Dobrava (DOBV) viruses and subsequently challenged them with PUUV. All animals immunized with PUUV and TOPV rN were completely protected [PubMed: 12050380]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010768 .

obo:VO_0007662 a rdfs:Class ;
  rdfs:label "GD2L, GD3L, Globo H, fucosyl GM1, and N-propionylated polysialic acid KLH conjugate vaccine" ;
  rdfs:comment "A cancer vaccine used to treat patients with small cell lung cancer by using several components (small cell lung cancer targets) that have been tested individually in patients with small cell lung cancer or other cancers (GD2, GD3, Globo H, Fucosyl GM1 and N-propionylated polysialic acid) so that the body will make antibodies to the vaccine which will also react against the cancer. Two other substances (KLH and OPT-821) are added which boost the immune system. Vaccination with the pentavalent KLH conjugate vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing any of these antigens." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0011168 a rdfs:Class ;
  rdfs:label "N nucleocapsid protein" ;
  rdfs:comment "Lewis rats were immunized with recombinant vaccinia virus (VV) expressing various proteins of measles virus (MV). VVN (Nucleocapsid Protein) -immunized rats survived a MV challenge infection [PubMed: 1833505]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010784 .

obo:VO_0011462 a rdfs:Class ;
  rdfs:label "Canine parvovirus DNA vaccine pGT36VP1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0012180 .

obo:VO_0020207 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (BA.4/BA.5) 0.025 MG/ML" ;
  rdfs:subClassOf obo:VO_0020497 .

obo:VO_0010030 a rdfs:Class ;
  rdfs:label "Neospora caninum MIC3" ;
  rdfs:comment "A MIC3 protein that is part of Neospora caninum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0021143 a rdfs:Class ;
  rdfs:label "influenza virus vaccine 2022-2023 (quadrivalent - Darwin/Victoria/Austria/Phuket) Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010428 .

obo:VO_0016522 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injectable Solution [HBvaxPRO] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015983 .

obo:VO_0001629 a rdfs:Class ;
  rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1232.15)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0015806 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection Box of 1" ;
  rdfs:subClassOf obo:VO_0015494 .

obo:VO_0010318 a rdfs:Class ;
  rdfs:label "influenza B virus B/Colorado/06/2017 antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003519 , obo:VO_0010301 .

obo:VO_0020256 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.008 MG/ML" ;
  rdfs:subClassOf obo:VO_0003345 .

obo:VO_0015976 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3" ;
  rdfs:subClassOf obo:VO_0015644 , obo:VO_0016060 .

obo:VO_0010734 a rdfs:Class ;
  rdfs:label "Priorix vaccine" ;
  rdfs:comment "A MMR vaccine that is manufactured by GlaxoSmithKline Biologicals." ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000641 , obo:VO_0000714 , obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0017549 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML [Boostrix]" ;
  rdfs:subClassOf obo:VO_0017548 .

obo:DOID_10154 a rdfs:Class ;
  rdfs:label "small intestine cancer"@en ;
  rdfs:comment "An intestinal cancer that is located_in the small intestine."@en ;
  rdfs:subClassOf obo:DOID_10155 .

obo:VO_0004163 a rdfs:Class ;
  rdfs:label "Neospora caninum DNA vaccine encoding NcSAG1 and NcSRS2, combined with recombinant NcSAG1 and NcSRS2 Protein" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000484 , obo:VO_0001065 .

obo:VO_0019767 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hawaii/66/2019 (H1N1) antigen 158000000 UNT/ML / influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML / influenza B virus B/Washington/02/2019 antigen 158000000 UNT/ML [Flumist Quadrivalent 2020-2021]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020352 .

obo:VO_0020030 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza virus vaccine, inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain Prefilled Syringe [Afluria 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0020028 , obo:VO_0020299 .

obo:VO_0000044 a rdfs:Class ;
  rdfs:label "FluMist" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000556 , obo:VO_0000714 , obo:VO_0001178 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0017322 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Pertussis Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Infanrix-Hib]" ;
  rdfs:subClassOf obo:VO_0017320 .

obo:VO_0001840 a rdfs:Class ;
  rdfs:label "Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 49A5.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000652 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002452 , obo:VO_0007748 , obo:VO_0010475 .

obo:VO_0020083 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 158000000 UNT/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza virus vaccine, live attenuated, A-Perth-16-2009 (H3N2) strain 158000000 UNT/ML [Flumist 2011-2012 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020348 .

obo:NCBITaxon_11019 a rdfs:Class ;
  rdfs:label "Alphavirus" ;
  rdfs:subClassOf obo:NCBITaxon_2732461 .

obo:VO_0018518 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0018516 .

obo:VO_0002331 a rdfs:Class ;
  rdfs:label "bovine rhinotracheitis vaccine-haemophilus somnus-mannheimia haemolytica-pasteurella multocida bacterin-toxoid" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000620 , obo:VO_0000987 , obo:VO_0001523 .

obo:VO_0017879 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0015069 .

obo:VO_0010366 a rdfs:Class ;
  rdfs:label "Zostavax (Refrigerator Stable) vaccine" ;
  rdfs:subClassOf obo:VO_0000124 .

obo:VO_0018272 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003862 .

obo:VO_0011412 a rdfs:Class ;
  rdfs:label "Mycobacterium tuberculosis Mtb72F protein subunit vaccine" ;
  rdfs:subClassOf obo:VO_0000077 , obo:VO_0000534 .

obo:VO_0007543 a rdfs:Class ;
  rdfs:label "FRAME-001 personalized vaccine" ;
  rdfs:comment "A cancer vaccine made from tumor-specific neopeptides resulting from frameshift mutations in tumor cells, so-called Frames, present potentially potent targets for the immune system and can be utilized in therapeutic anti-cancer vaccination with the intention to synergize in their effect with immune checkpoint inhibitors. The personalized vaccine FRAME-001 based on a patient's Framome and selection of Frame peptides in advanced NSCLC cancer patients after standard first line treatment consisting of immune checkpoint inhibitor pembrolizumab as monotherapy or combined with chemotherapy (carboplatin/cisplatin and pemetrexed/paclitaxel) could help treat patients with non-small cell lung cancer." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0003140 , obo:VO_0007657 .

obo:VO_0011438 a rdfs:Class ;
  rdfs:label "Burkholderia pseudomallei subunit PotF protein vaccine" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0012175 .

obo:VO_0002648 a rdfs:Class ;
  rdfs:label "msbB from Salmonella Typhimurium" ;
  rdfs:comment "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0003744 a rdfs:Class ;
  rdfs:label "Afluria Quadrivalent 2016-2017 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000578 , obo:VO_0001817 , obo:VO_0010432 .

obo:VO_0004314 a rdfs:Class ;
  rdfs:label "Yersinia pestis DNA vaccine F1-V DNA" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000648 .

obo:VO_0018359 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG/ML" ;
  rdfs:subClassOf obo:VO_0003340 .

obo:VO_0011277 a rdfs:Class ;
  rdfs:label "H2B" ;
  rdfs:comment "Researchers tested the ability of the entire H2B protein of L. major, its divergent or conserved regions to provide protection against virulent L. major challenge.  The divergent amino-terminal region of H2B is able to confer potent protection against a virulent challenge in BALB/c mice [PubMed: 16417957]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0020187 a rdfs:Class ;
  rdfs:label "rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain Oral Suspension" ;
  rdfs:subClassOf obo:VO_0004815 .

obo:NCBITaxon_1980915 a rdfs:Class ;
  rdfs:label "Novirhabdovirus hirame" ;
  rdfs:subClassOf obo:NCBITaxon_186778 .

obo:VO_0021020 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2000 PFU [Varilrix]" ;
  rdfs:subClassOf obo:VO_0010746 , obo:VO_0021019 .

obo:NCBITaxon_40674 a rdfs:Class ;
  rdfs:label "Mammalia" ;
  rdfs:subClassOf obo:NCBITaxon_32524 .

obo:VO_0018253 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 10000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:NCBITaxon_546272 a rdfs:Class ;
  rdfs:label "Brucella melitensis ATCC 23457" ;
  rdfs:subClassOf obo:NCBITaxon_29459 .

obo:VO_0012375 a rdfs:Class ;
  rdfs:label "Gap" ;
  rdfs:comment "GAPDH (Gap) associated with murine IL-12 gene in a DNA vaccine formulation partially protected mice against experimental infection [PubMed: 12171297]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010758 .

obo:VO_0003339 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0000501 a rdfs:Class ;
  rdfs:label "E. coli vaccine using verocytotoxin toxoid" ;
  rdfs:subClassOf obo:VO_0000963 .

obo:VO_0020679 a rdfs:Class ;
  rdfs:label "A/Hong Kong/4801/2014 (H3n2) - Like Virus / Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain / Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008 strain Injectable Suspension [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0020677 .

obo:VO_0019970 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone 2014-2015 Formula]" ;
  rdfs:subClassOf obo:VO_0019951 .

obo:VO_0018479 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 20 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0018440 , obo:VO_0018459 .

obo:VO_0019600 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Nasal Spray [FluMist Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0019592 , obo:VO_0020354 .

obo:VO_0020399 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0020383 .

obo:VO_0019988 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Fluvirin 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019976 .

obo:VO_0002886 a rdfs:Class ;
  rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine (merged to VO_0002885)" ;
  rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" .

obo:VO_0003640 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2017-2018]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003638 .

obo:VO_0002419 a rdfs:Class ;
  rdfs:label "canine parvovirus vaccine-leptospira canicola icterohaemorrhagiae bacterin" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0001471 , obo:VO_0012180 .

obo:VO_0016601 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix]" ;
  rdfs:subClassOf obo:VO_0016562 , obo:VO_0016607 .

obo:VO_0001654 a rdfs:Class ;
  rdfs:label "Bursal Disease Standard & Variant, Killed Virus Vaccine (USDA: 12B5.41)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000960 , obo:VO_0007748 .

obo:VO_0019268 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010433 .

obo:VO_0003344 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003285 , obo:VO_0010445 , obo:VO_0010453 .

obo:VO_0005406 a rdfs:Class ;
  rdfs:label "Betuvax-CoV2 vaccine" ;
  rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Human Stem Cell Institute" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0004832 a rdfs:Class ;
  rdfs:label "RotaTeq, Rotavirus, live pentavalent (RV5) Oral Vaccine" ;
  rdfs:subClassOf obo:VO_0004830 .

obo:VO_0019771 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2454/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010424 .

obo:VO_0020007 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.12 MG/ML [Fluzone High-Dose 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0004914 , obo:VO_0020480 .

obo:VO_0003849 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003443 , obo:VO_0010451 .

obo:VO_0003371 a rdfs:Class ;
  rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010456 .

obo:DOID_8557 a rdfs:Class ;
  rdfs:label "oropharynx cancer"@en ;
  rdfs:comment "A pharynx cancer that is located_in the oropharynx."@en ;
  rdfs:subClassOf obo:DOID_0060119 .

obo:VO_0018148 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution [Mmr Priorix] Box of 25" ;
  rdfs:subClassOf obo:VO_0018144 , obo:VO_0018158 .

obo:VO_0017724 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension Box of 10" ;
  rdfs:subClassOf obo:VO_0017713 , obo:VO_0017785 .

obo:VO_0018662 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 6 Vaccine 0.02 MG/ML" ;
  rdfs:subClassOf obo:VO_0003300 .

obo:VO_0000551 a rdfs:Class ;
  rdfs:label "obsolete licensed veterinary vaccine role" ;
  rdfs:comment "A licensed vaccine role that is bears in a licensed veterinary vaccine." .

obo:VO_0016915 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.0936 MG/ML / diphtheria toxoid vaccine, inactivated 60 UNT/ML / Human poliovirus 160 BAU/ML / tetanus toxoid vaccine, inactivated 80 UNT/ML Injectable Suspension [Tetravac] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016914 .

obo:VO_0015492 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015500 .

obo:VO_0017218 a rdfs:Class ;
  rdfs:label "50 ML tetanus toxoid vaccine, inactivated 1.5 UNT/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0017215 , obo:VO_0017469 .

obo:VO_0007333 a rdfs:Class ;
  rdfs:label "rMVA-PSA/PSMA/TRICOM vaccine" ;
  rdfs:comment "A cancer vaccine consisting of recombinant modified vaccinia Ankara (rMVA) encoding the prostate specific antigen (PSA), the prostate-specific membrane antigen (PSMA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). Vaccination with PSA/PSMA in combination with TRICOM may enhance antigen presentation, resulting in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells over-expressing PSA or PSMA." ;
  rdfs:subClassOf obo:VO_0005425 , obo:VO_0007657 .

obo:VO_0016809 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 60 LFU/ML Injectable Suspension [Tetravac] Box of 10" ;
  rdfs:subClassOf obo:VO_0016729 , obo:VO_0016751 , obo:VO_0016825 .

obo:VO_0020758 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 12.5 MG" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0019465 .

obo:VO_0007361 a rdfs:Class ;
  rdfs:label "Chimeric Ad11p/Ad3 Oncolytic Virus Vaccine" ;
  rdfs:comment "A complex, replication-selective, E1B and partial E3 gene deleted, adenovirus type 11p (Ad11p)/Ad3 chimeric oncolytic virus with potential antineoplastic activity. Upon intralesional injection of enadenotucirev, the adenovirus selectively and rapidly replicates in cancer cells; however, it is unable to replicate in normal, healthy cells. This induces a selective adenovirus-mediated cytotoxicity in cancer cells, which leads to cancer cell lysis. Following the lysis of infected cells, the replicated virus is released and can infect adjacent cells, which both induces further tumor cell oncolysis and may activate the immune system to kill the infected tumor cells. The E1B protein causes p53 inactivation in host cells, which promotes viral replication. Deletion of E1B prevents replication in normal, healthy cells that express wild-type p53. The mutation and subsequent inactivation of p53 in cancer cells enables the E1B-deleted adenovirus to selectively replicate in cancer cells. Partial deletion of the E3 gene, which encodes the adenovirus death protein, enhances the safety profile of the administered adenovirus." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0019542 a rdfs:Class ;
  rdfs:label "human-bovine reassortant rotavirus strain G1 vaccine / human-bovine reassortant rotavirus strain G2 vaccine / human-bovine reassortant rotavirus strain G3 vaccine / human-bovine reassortant rotavirus strain G4 vaccine / human-bovine reassortant rotavirus strain P1A[8] vaccine Oral Suspension [RotaTeq]" ;
  rdfs:subClassOf obo:VO_0000097 , obo:VO_0010217 .

obo:VO_0003455 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000508 , obo:VO_0001214 , obo:VO_0010445 .

obo:VO_0010228 a rdfs:Class ;
  rdfs:label "yellow fever vaccine, unspecified formulation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010456 .

obo:VO_0015284 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 25000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0016330 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 1 by Cc" ;
  rdfs:subClassOf obo:VO_0015938 .

obo:VO_0004597 a rdfs:Class ;
  rdfs:label "SHIV(Ba-L) DNA vaccine encoding env and gag" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000295 .

obo:VO_0001922 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4435.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0000813 , obo:VO_0001214 , obo:VO_0002349 .

obo:VO_0000095 a rdfs:Class ;
  rdfs:label "Rabies vaccine Adsorbed by BioPort Corp" ;
  rdfs:comment "Product Name: Rabies Vaccine Adsorbed" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010448 .

obo:VO_0016983 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group C polysaccharide 0.02 MG/ML / tetanus toxoid vaccine, inactivated 0.04 MG/ML Injectable Suspension [Neisvac C] by Pfizer" ;
  rdfs:subClassOf obo:VO_0016982 .

obo:VO_0020239 a rdfs:Class ;
  rdfs:label "smallpox vaccine live, New York City Board of Health vaccinia strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0020229 .

obo:VO_0015785 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension Box of 20" ;
  rdfs:subClassOf obo:VO_0015596 .

obo:VO_0007488 a rdfs:Class ;
  rdfs:label "gp100-Reactive Autologous Peripheral Blood Lymphocyte vaccine" ;
  rdfs:comment "Human peripheral blood lymphocytes (PBL) isolated from a patient, exposed to the tumor-associated antigen gp100 in vitro, and then transferred back to the same patient to target tumor sites expressing gp100. gp100 human antigen is a wild-type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:OBI_0000969 a rdfs:Class ;
  rdfs:label "dose specification" ;
  rdfs:comment "a directive information entity that describes the dose that will be administered to a target"@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:VO_0000720 a rdfs:Class ;
  rdfs:label "Brucella abortus strain RB51SOD vaccine" ;
  rdfs:subClassOf obo:VO_0001134 .

obo:VO_0010288 a rdfs:Class ;
  rdfs:label "study design variable" ;
  rdfs:comment "A directive information entity that is part of a study design. It can be eithor independent variables whose values are selected to determine its relationship to an observed phenomenon (the dependent variable) or dependent variables that are studied and expected to change when the independent variable varies." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:VO_0020493 a rdfs:Class ;
  rdfs:label "Fluzone Quadrivalent 2021-2022 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003073 , obo:VO_0010423 .

obo:VO_0003954 a rdfs:Class ;
  rdfs:label "0.5 ML Ixiaro 0.012 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003953 .

obo:VO_0001755 a rdfs:Class ;
  rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.21)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001471 , obo:VO_0007748 , obo:VO_0012180 .

obo:VO_0017706 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0017685 , obo:VO_0017753 .

obo:VO_0016898 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML / Bordetella pertussis 0.025 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Covaxis] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016897 .

obo:VO_0000232 a rdfs:Class ;
  rdfs:label "pCR3 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0011175 a rdfs:Class ;
  rdfs:label "Apa" ;
  rdfs:comment "We show that the 50- to 55-kDa Apa protein, specified by the Rv1860 gene of M. tuberculosis, can elicit both lymphoproliferative response and gamma interferon (IFN-gamma) production.  A poxvirus recombinant expressing the Apa protein conferred a significant level of protective immunity in guinea pigs against a challenge dose of virulent M. tuberculosis [PubMed: 12654810]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010770 .

obo:VO_0010373 a rdfs:Class ;
  rdfs:label "(Refrigerated) - ProQuad vaccine" ;
  rdfs:subClassOf obo:VO_0000091 .

obo:VO_0007350 a rdfs:Class ;
  rdfs:label "CAP-3 (CEA Peptide 9-mer) Vaccine" ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005489 , obo:VO_0007657 .

obo:VO_0003072 a rdfs:Class ;
  rdfs:label "FluLaval Tetra vaccine" ;
  rdfs:comment "Product Name: Quadrivalent Influenza Vaccine (Split Virion, Inactivated)" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0002495 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0021031 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Prefilled Syringe Box of 1" ;
  rdfs:subClassOf obo:VO_0021028 .

obo:VO_0002492 a rdfs:Class ;
  rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46L9.20)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0001217 , obo:VO_0001220 , obo:VO_0002404 , obo:VO_0007748 .

obo:VO_0016982 a rdfs:Class ;
  rdfs:label "0.5 ML meningococcal group C polysaccharide 0.02 MG/ML / tetanus toxoid vaccine, inactivated 0.04 MG/ML Injectable Suspension [Neisvac C]" ;
  rdfs:subClassOf obo:VO_0016981 , obo:VO_0017454 .

obo:VO_0004901 a rdfs:Class ;
  rdfs:label "influenza B virus B/Wisconsin/1/2010 antigen" ;
  rdfs:subClassOf obo:VO_0015086 .

obo:UBERON_0001638 a rdfs:Class ;
  rdfs:label "vein" ;
  rdfs:comment "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." ;
  rdfs:subClassOf obo:UBERON_0001981 .

obo:VO_0000778 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum ABRA protein vaccine" ;
  rdfs:subClassOf obo:VO_0000087 .

obo:VO_0000776 a rdfs:Class ;
  rdfs:label "P. vivax PVS25 vaccine with Montanide ISA-720 adjuvant" ;
  rdfs:subClassOf obo:VO_0000758 .

obo:VO_0002561 a rdfs:Class ;
  rdfs:label "bp26 from B. melitensis" ;
  rdfs:comment "A bp26 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001400 .

obo:VO_0020367 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Injectable Suspension [Hepatyrix]" ;
  rdfs:subClassOf obo:VO_0020374 .

obo:NCBITaxon_10239 a rdfs:Class ;
  rdfs:label "Viruses" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:VO_0019778 a rdfs:Class ;
  rdfs:label "influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Washington/02/2019 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010425 .

obo:VO_0000055 a rdfs:Class ;
  rdfs:label "vaccine related journal article" ;
  rdfs:comment "A jourmal article that mentions a vaccine, which was retrieved from PubMed and annotated using VO-SciMinner." ;
  rdfs:subClassOf obo:IAO_0000013 .

obo:IAO_0000142 a rdf:Property ;
  rdfs:label "mentions"@en ;
  rdfs:comment "An information artifact IA mentions an entity E exactly when it has a component/part that denotes E"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:VO_0001405 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus gene" ;
  rdfs:comment "A bacterial gene that is from Staphylococcus aureus." ;
  rdfs:subClassOf obo:OGG_2000000002 .

obo:VO_0015206 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0015300 .

obo:VO_0010266 a rdfs:Class ;
  rdfs:label "host age datum" ;
  rdfs:comment "A measurment datum that records  the age of thost." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:PATO_0000165 a rdfs:Class ;
  rdfs:label "time" ;
  rdfs:comment "A quality in which events occur in sequence." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:NCBITaxon_10358 a rdfs:Class ;
  rdfs:label "Cytomegalovirus" ;
  rdfs:subClassOf obo:NCBITaxon_10357 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data item"@en ;
  rdfs:comment "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0017888 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003408 , obo:VO_0010437 .

obo:VO_0017913 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injectable Solution [Invivac]" ;
  rdfs:subClassOf obo:VO_0010444 , obo:VO_0017818 .

obo:VO_0021091 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe [Infanrix]" ;
  rdfs:subClassOf obo:VO_0000064 .

obo:VO_0015315 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003430 .

obo:VO_0015213 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015211 .

obo:OPL_0000078 a rdfs:Class ;
  rdfs:label "erythrocytic schizont stage" ;
  rdfs:comment "A schizont stage that occurs in erythrocytes where trophozoites mature into a schizont and schizont produces daughter trophozoites or merozoites." ;
  rdfs:subClassOf obo:OPL_0000084 .

obo:VO_0005180 a rdfs:Class ;
  rdfs:label "nanoparticle vector" ;
  rdfs:comment "Vaccine vector that is a tiny particle, typically in the nanometer size range, used to deliver genetic code to specific cells within the body." ;
  rdfs:subClassOf obo:VO_0003674 .

obo:NCBITaxon_731 a rdfs:Class ;
  rdfs:label "Histophilus somni" ;
  rdfs:subClassOf obo:NCBITaxon_712 .

obo:VO_0010035 a rdfs:Class ;
  rdfs:label "Neospora caninum p24" ;
  rdfs:comment "A p24 protein that is part of Neospora caninum" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010828 .

obo:VO_0001440 a rdfs:Class ;
  rdfs:label "Infectious Hematopoietic Necrosis Virus gene" ;
  rdfs:comment "A viral gene that is from Infectious Hematopoietic Necrosis Virus." ;
  rdfs:subClassOf obo:VO_0000156 .

obo:VO_0018916 a rdfs:Class ;
  rdfs:label "influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0019149 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000738 , obo:VO_0001214 .

obo:VO_0019370 a rdfs:Class ;
  rdfs:label "1 ML hepatitis B surface antigen vaccine 0.04 MG/ML Injection [Recombivax]" ;
  rdfs:subClassOf obo:VO_0019369 , obo:VO_0019532 .

obo:OGMS_0000061 a rdfs:Class ;
  rdfs:label "pathological bodily process" ;
  rdfs:comment "A bodily process that is clinically abnormal."@en ;
  rdfs:subClassOf obo:OGMS_0000060 .

obo:VO_0016007 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 1" ;
  rdfs:subClassOf obo:VO_0015661 , obo:VO_0015794 .

obo:VO_0016562 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix]" ;
  rdfs:subClassOf obo:VO_0000113 , obo:VO_0016559 .

obo:VO_0015622 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix B]" ;
  rdfs:subClassOf obo:VO_0015576 , obo:VO_0015577 , obo:VO_0015662 .

obo:VO_0011090 a rdfs:Class ;
  rdfs:label "M Segment" ;
  rdfs:comment "Researchers vaccinated hamsters with a vaccinia virus-vectored vaccine expressing the M and the S segments of Hantaan (HTN) virus and challenged them with HTN, Seoul (SEO), or Puumala (PUU) virus.  Study found that vaccinated hamsters, challenged with HTN or SEO virus, were neither viremic nor had evidence of virus in their lungs or kidneys [PubMed: 7666542]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010768 .

obo:VO_0003701 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2016-2017 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003699 .

obo:OPL_0000130 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum merozoite" ;
  rdfs:comment "A Plasmodium falciparum that is produced in a schizont, found in the bloodstream of a human host and invades erythrocytes." ;
  rdfs:subClassOf obo:NCBITaxon_5833 , obo:OPL_0000270 .

obo:VO_0017113 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur] by Novartis" ;
  rdfs:subClassOf obo:VO_0017108 .

obo:VO_0020807 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain Injectable Suspension [OncoTICE]" ;
  rdfs:subClassOf obo:VO_0020806 .

obo:VO_0017793 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 15000000000 UNT/ML Injectable Suspension Box of 5 by Aventis" ;
  rdfs:subClassOf obo:VO_0017792 .

obo:VO_0020780 a rdfs:Class ;
  rdfs:label "BCG, Live, Tice Strain 200000000 ORGANISMS" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0019465 .

obo:NCBITaxon_10334 a rdfs:Class ;
  rdfs:label "Felid alphaherpesvirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_10319 .

obo:VO_0018086 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 TCID/ML Injectable Solution [Priorix] Box of 10" ;
  rdfs:subClassOf obo:VO_0018085 , obo:VO_0018091 , obo:VO_0018168 .

obo:VO_0010723 a rdfs:Class ;
  rdfs:label "Liquid Pedvax HIB vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000714 , obo:VO_0010437 .

obo:VO_0011332 a rdfs:Class ;
  rdfs:label "Pmp1" ;
  rdfs:comment "Recombinant Pmp1 was reactive with serum from individuals with both acute and protracted disease, and evoked protection in two murine models of infection with C. posadasii [PubMed: 16495561]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010853 .

obo:VO_0011383 a rdfs:Class ;
  rdfs:label "Bovine herpesvirus 1 GPI protein vaccine" ;
  rdfs:subClassOf obo:VO_0000987 .

obo:VO_0005189 a rdfs:Class ;
  rdfs:label "hAd5-COVID-19 vaccine" ;
  rdfs:comment "A SARS-CoV-2 human adenovirus serotype 5 (hAd5) vector vaccine with E1/E2b/E3 deletions expressing SARS-CoV-2 viral antigen spike fusion protein and nucleocapsid with an enhanced T-cell stimulation domain." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:VO_0016377 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 1 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015941 .

obo:VO_0000824 a rdfs:Class ;
  rdfs:label "MVA expressing HIV Gag, Pol and Env proteins vaccine" ;
  rdfs:comment "A recombinant modified vaccinia Ankara (MVA) expressing HIV Gag, Pol, and Env proteins. PMID:16472543." ;
  rdfs:subClassOf obo:VO_0000295 .

obo:VO_0019305 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.03 MG/ML / influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.03 MG/ML Prefilled Syringe [Flucelvax 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019301 , obo:VO_0020328 .

obo:VO_0010078 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi TcSSP4" ;
  rdfs:comment "A TcSSP4 protein that is part of Trypanosoma cruzi" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0002307 a rdfs:Class ;
  rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 49B1.21)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000619 , obo:VO_0001220 , obo:VO_0002469 , obo:VO_0007748 .

obo:VO_0018163 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 /ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 25000 /ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 /ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0018162 .

obo:VO_0020624 a rdfs:Class ;
  rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 4000 UNT/ML Injectable Solution [Varilrix] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0020623 .

obo:BFO_0000024 a rdfs:Class ;
  rdfs:label "fiat object part"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0015869 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015614 , obo:VO_0015691 , obo:VO_0015993 .

obo:VO_0018321 a rdfs:Class ;
  rdfs:label "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injectable Solution [Rabivac] Box of 5" ;
  rdfs:subClassOf obo:VO_0018291 , obo:VO_0018304 , obo:VO_0018324 .

obo:VO_0001238 a rdfs:Class ;
  rdfs:label "Ribi vaccine adjuvant" ;
  rdfs:comment "An emulsion vaccine adjuvant that is a stable oil-in-water emulsion." ;
  rdfs:subClassOf obo:VO_0001355 .

obo:VO_0010247 a rdfs:Class ;
  rdfs:label "pathogen variable" ;
  rdfs:comment "A variable representing the species or type of the pathogen" ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0021105 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/6/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Austria/1359417/2021 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2022-2023]" ;
  rdfs:subClassOf obo:VO_0020306 .

obo:VO_0015325 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine, Inactivated / Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Intramuscular Solution" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010438 , obo:VO_0010451 , obo:VO_0015322 .

obo:VO_0000702 a rdfs:Class ;
  rdfs:label "obsolete recombinant viral vector vaccine role" ;
  rdfs:comment "A recombinant vector vaccine role that inheres in a virus that carries a vaccine antigen for development of a particular vaccine " .

obo:VO_0011451 a rdfs:Class ;
  rdfs:label "Entamoeba histolytica Gal/GalNAc lectin protein vaccine" ;
  rdfs:subClassOf obo:VO_0012171 .

obo:VO_0003794 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2017-2018 Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0003792 .

obo:VO_0020899 a rdfs:Class ;
  rdfs:label "influenza A virus (H1N1) antigen Injectable Suspension [Preflucel]" ;
  rdfs:subClassOf obo:VO_0020887 .

obo:VO_0017665 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [T-Immun Immuno]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0010254 a rdfs:Class ;
  rdfs:label "vaccination interval variable" ;
  rdfs:comment "A variable representing the interval between multiple vaccinations." ;
  rdfs:subClassOf obo:VO_0010288 .

obo:VO_0017691 a rdfs:Class ;
  rdfs:label "0.5 ML acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Pediacel] Box of 10" ;
  rdfs:subClassOf obo:VO_0017690 , obo:VO_0017704 , obo:VO_0017745 .

obo:VO_0018202 a rdfs:Class ;
  rdfs:label "MEASLES VIRUS VACCINE,LIVE ATTENUATED / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injection [Priorix]" ;
  rdfs:subClassOf obo:VO_0010734 , obo:VO_0018201 .

obo:VO_0007246 a rdfs:Class ;
  rdfs:label "ALVAC-hB7.1 vaccine" ;
  rdfs:comment "A vaccine comprise of a canarypox viral vector that carries the gene for human B7.1 (CD80 antigen) with potential use as an autologous therapeutic cancer vaccine. Tumor cells harvested from a patient are infected with ALVAC-hB7 1, thereby producing an autologous cell line that exhibits increased expression of HLA class I and class II, CD54 (ICAM), and CD80. Increased expression of these proteins by this autologous cell line may activate an antitumor T-cell response when the modified cells are administered to the patient." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0015821 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] by Sanofi" ;
  rdfs:subClassOf obo:VO_0015614 .

obo:VO_0002523 a rdfs:Class ;
  rdfs:label "apxIVA from Actinobacillus pleuropneumoniae" ;
  rdfs:comment "A precisely defined DeltaapxIICDeltaapxIVA double-deletion mutant of A. pleuropneumoniae was constructed based on HB04C(-) by transconjugation and counterselection. The results demonstrated that the DeltaapxIICDeltaapxIVA double mutant strain was less virulent than HB04C(-). Despite attenuation of virulence, the DeltaapxIICDeltaapxIVA double mutant remains immunogenic and conferred a similar level of protective immunity to pigs against challenge with a lethal dose of a heterologous fully virulent standard serovar 1 strain of A. pleuropneumoniae" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001384 .

obo:VO_0011300 a rdfs:Class ;
  rdfs:label "T. cruzi PAR2" ;
  rdfs:comment "C57BL/6 mice were immunized s.c. with recombinant PFR-2 (PAR2)  protein co-adsorbed to alum with rIL-12. rPFR-2 immunized animals were able to successfully resolve parasitemia by day 30 p.i., with the peak parasitemia occurring between days 17 and 21 p.i. [PubMed: 12798650]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010838 .

obo:VO_0000284 a rdfs:Class ;
  rdfs:label "pMASIA DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0018799 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine, inactivated 0.012 MG/ML" ;
  rdfs:subClassOf obo:VO_0003948 .

obo:VO_0020946 a rdfs:Class ;
  rdfs:label "influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML Nasal Spray" ;
  rdfs:subClassOf obo:VO_0020941 .

obo:VO_0003820 a rdfs:Class ;
  rdfs:label "Flumist Quadrivalent 2018-2019 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000982 , obo:VO_0010431 .

obo:VO_0003651 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2018-2019]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0003649 .

obo:VO_0010827 a rdfs:Class ;
  rdfs:label "Babesia bovis protein" ;
  rdfs:subClassOf obo:VO_0010755 .

obo:VO_0000952 a rdfs:Class ;
  rdfs:label "Dhori virus vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000609 .

obo:VO_0007050 a rdfs:Class ;
  rdfs:label "therapeutic Breast/Ovarian/Prostate peptide cancer vaccine DPX-0907" ;
  rdfs:comment "A lipid-based multi-peptide cancer vaccine targeted against multiple cancers with immunopotentiating activity. Therapeutic breast/ovarian/prostate peptide cancer vaccine DPX-0907 is a lyophilized liposomal proprietary preparation comprised of 7 tumor-specific HLA-A2-restricted epitopes (TAAs): topoisomerase II alpha, B-cell receptor-associated protein 31 (CDM protein), TNF-alpha-converting enzyme (TACE/ADAM17), Abelson homolog 2 (Abl2), gamma catenin (Junction plakoglobin), epithelial discoidin domain receptor 1 (EDDR1) and integrin beta 8 subunit. Upon vaccination, the lyophilized antigen/adjuvant/liposome complex is re-suspended in Montanide 1SA51 VG to create a depot effect, thereby presenting the TAAs to the immune system for a prolonged period of time. This may stimulate a potent cytotoxic T-lymphocyte (CTL) immune response against cancer cells that express these 7 TAAs and share epitopes with the vaccine epitope peptides, resulting in tumor cell lysis. The 7 TAAs are overexpressed on the surface of breast/ovarian and prostate cancer cells and play an important role in tumor cell growth and survival." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005425 , obo:VO_0005484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0007206 a rdfs:Class ;
  rdfs:label "Adenovirus HER2-Transduced Autologous Dendritic Cell Vaccine" ;
  rdfs:comment "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a replication-deficient adenovirus vector encoding HER-2 with potential antineoplastic activity. Upon administration, adenovirus HER2-transduced autologous dendritic cell vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against HER-2-positive tumor cells, which may result in tumor cell death and decreased tumor growth. HER-2, a tyrosine kinase receptor for epidermal growth factor (EGF) (also known as neu and ErbB2), is overexpressed by some breast, ovarian, and gastric cancers." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:VO_0004496 a rdfs:Class ;
  rdfs:label "Mycobacterium marinum pCMV-85A vaccine" ;
  rdfs:subClassOf obo:VO_0003058 .

obo:VO_0000665 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus vaccine" ;
  rdfs:comment "A viral vaccine that protects against infection with Japanese encephalitis virus." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003546 .

obo:VO_0001171 a rdfs:Class ;
  rdfs:label "Brucella melitensis Rev. 1 with bp26 and omp31 deletions vaccine" ;
  rdfs:comment "B. melitensis bp26 and omp31 deletion vaccine is a Brucella melitensis vaccine that has double deletions of bp26 and omp31." ;
  rdfs:subClassOf obo:VO_0001135 .

obo:VO_0019711 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Injection [Flublok 2015-2016]" ;
  rdfs:subClassOf obo:VO_0003886 , obo:VO_0010427 , obo:VO_0019710 .

obo:OPL_0000085 a rdfs:Class ;
  rdfs:label "macrogamete stage" ;
  rdfs:comment "A gamete stage in parasites when macrogametocytes produce macrogametes through the process known as gametogenesis." ;
  rdfs:subClassOf obo:OPL_0000181 , obo:OPL_0000260 .

obo:VO_0019351 a rdfs:Class ;
  rdfs:label "0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020472 .

obo:VO_0004032 a rdfs:Class ;
  rdfs:label "Listeria monocytogenes p60 Protein vaccine" ;
  rdfs:subClassOf obo:VO_0002500 .

obo:VO_0000745 a rdfs:Class ;
  rdfs:label "licensed human Hepatitis A & B vaccine" ;
  rdfs:subClassOf obo:VO_0010438 , obo:VO_0010439 .

obo:VO_0020337 a rdfs:Class ;
  rdfs:label "Flulaval 2011-2012 Formula vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000043 , obo:VO_0010419 .

obo:VO_0017047 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 150 UNT/ML Prefilled Syringe Box of 20" ;
  rdfs:subClassOf obo:VO_0017031 , obo:VO_0017516 .

obo:VO_0007540 a rdfs:Class ;
  rdfs:label "MAGE-A3-expressing Adenovirus Type 5 vaccine" ;
  rdfs:comment "An oncolytic adenoviral vaccine composed of a replication-defective, E1- and E3-deleted adenovirus serotype 5 (Ad5) with a transgene encoding the human melanoma antigen A3 (MAGE-A3), with potential antineoplastic activity. Upon administration, MAGE-A3-expressing adenovirus type 5 vaccine selectively replicates in cancer cells and expresses MAGE-A3. This induces an immune response against tumor cells expressing the MAGE-A3 antigen, which leads to tumor cell death. The tumor-associated antigen MAGE-A3 is overexpressed by a variety of cancer cell types." ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0019470 a rdfs:Class ;
  rdfs:label "Haemophilus capsular oligosaccharide / Neisseria meningitidis Injectable Suspension [Liquid PedvaxHIB]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003192 , obo:VO_0010437 , obo:VO_0010444 .

obo:VO_0021081 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Quadracel]" ;
  rdfs:subClassOf obo:VO_0010736 .

obo:VO_0007322 a rdfs:Class ;
  rdfs:label "autologous-cell melanoma vaccine" ;
  rdfs:comment "An autologous-cell vaccine for melanoma." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0007627 a rdfs:Class ;
  rdfs:label "ipilimumab, vemurafenib vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0018106 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 20000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018240 .

obo:VO_0002347 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0002337 .

obo:VO_0003135 a rdfs:Class ;
  rdfs:label "YF-17DD vaccine" ;
  rdfs:comment "A Yellow fever virus vaccine that uses the live attenated 17DD strain." ;
  rdfs:subClassOf obo:VO_0000123 , obo:VO_0001220 .

obo:VO_0015295 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 48 UNT/ML Prefilled Syringe [Epaxal] Box of 10" ;
  rdfs:subClassOf obo:VO_0015293 , obo:VO_0015297 .

obo:VO_0017533 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 250 UNT/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0017531 .

obo:VO_0015033 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 18 Vaccine 0.08 MG/ML" ;
  rdfs:subClassOf obo:VO_0003302 .

obo:VO_0011013 a rdfs:Class ;
  rdfs:label "HpmB" ;
  rdfs:comment "Using a mouse plague model, YPO3720 (hpmB) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010759 .

obo:VO_0020334 a rdfs:Class ;
  rdfs:label "Flucelvax Quadrivalent 2021-2022 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0003070 , obo:VO_0010423 .

obo:NCBITaxon_11158 a rdfs:Class ;
  rdfs:label "Paramyxoviridae" ;
  rdfs:subClassOf obo:NCBITaxon_11157 .

obo:VO_0020997 a rdfs:Class ;
  rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 1350 PFU" ;
  rdfs:subClassOf obo:VO_0003273 .

obo:NCBITaxon_2 a rdfs:Class ;
  rdfs:label "Bacteria" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:VO_0004549 a rdfs:Class ;
  rdfs:label "Dengue virus DNA vaccine encoding NS1" ;
  rdfs:subClassOf obo:VO_0000032 , obo:VO_0000725 .

obo:DOID_9261 a rdfs:Class ;
  rdfs:label "nasopharynx carcinoma"@en ;
  rdfs:comment "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract."@en ;
  rdfs:subClassOf obo:DOID_0050615 , obo:DOID_0060119 , obo:DOID_305 .

obo:VO_0000921 a rdfs:Class ;
  rdfs:label "bovine serum cell culture residual in vaccine" ;
  rdfs:comment "a cell culture residual in vaccine that is bovine serum." ;
  rdfs:subClassOf obo:VO_0000856 .

obo:VO_0002280 a rdfs:Class ;
  rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.22)" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0002461 , obo:VO_0007748 .

obo:VO_0020255 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.004 MG/ML" ;
  rdfs:subClassOf obo:VO_0003342 .

obo:VO_0000321 a rdfs:Class ;
  rdfs:label "Brucella abortus DNA vaccine encoding BCSP31, SOD and L7/L12" ;
  rdfs:subClassOf obo:VO_0001225 .

obo:VO_0007016 a rdfs:Class ;
  rdfs:label "Recombinant Modified Vaccinia Ankara-5T4 Vaccine" ;
  rdfs:comment "A cancer vaccine comprised of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the 5T4 fetal oncoprotein (MVA-h5T4). Vaccination with recombinant modified vaccinia Ankara-5T4 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing 5T4 fetal oncoprotein antigen, resulting in tumor cell lysis. The MVA viral vector, derived from the replication-competent strain Ankara, is a highly attentuated, replication-defective vaccinia strain incapable of virion assembly." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005484 , obo:VO_0007657 .

obo:UBERON_0001255 a rdfs:Class ;
  rdfs:label "urinary bladder" ;
  rdfs:comment "Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]." ;
  rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0018707 .

obo:VO_0011372 a rdfs:Class ;
  rdfs:label "cancer retroviral vector vaccine encoding Cd40lg" ;
  rdfs:subClassOf obo:VO_0007657 .

obo:VO_0007075 a rdfs:Class ;
  rdfs:label "Tumor Cell Derivative Vaccine" ;
  rdfs:comment "A vaccine made of cancer cells, parts of cancer cells, or pure tumor antigens (substances isolated from tumor cells). A tumor antigen vaccine may stimulate the body's immune system to find and kill cancer cells." ;
  rdfs:subClassOf obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0007434 a rdfs:Class ;
  rdfs:label "Globo H-DT vaccine OBI-833" ;
  rdfs:comment "A carbohydrate-based vaccine comprised of the Globo H hexasaccharide 1 (Globo H) antigen conjugated to DT-CRM197, a non-toxic, mutated form of diphtheria toxin (DT), with potential immunostimulating and antineoplastic activities. Upon administration of Globo H-DT vaccine OBI-833, the carbohydrate antigen Globo H may stimulate a cytotoxic T-lymphocyte (CTL) response against Globo H-expressing tumor cells, thereby decreasing tumor cell proliferation. The hexasaccharide Globo H is a tumor-associated antigen (TAA) commonly found on a variety of tumor cells. DT-CRM197, also called diphtheria toxin cross-reacting material 197, is used to increase the immunogenicity of the Globo H carbohydrate antigen." ;
  rdfs:subClassOf obo:VO_0005426 , obo:VO_0005484 , obo:VO_0005486 , obo:VO_0005490 , obo:VO_0005496 , obo:VO_0007657 .

obo:VO_0018613 a rdfs:Class ;
  rdfs:label "Japanese encephalitis virus Injectable Suspension [Ixiaro]" ;
  rdfs:subClassOf obo:VO_0011558 , obo:VO_0018612 .

obo:VO_0010007 a rdfs:Class ;
  rdfs:label "Eimeria maxima gam56" ;
  rdfs:comment "A gam56 protein that is part of Eimeria maxima" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010833 .

obo:VO_0000940 a rdfs:Class ;
  rdfs:label "yeast protein cell culture residual in vaccine" ;
  rdfs:comment "a cell culture residual in vaccine that is yeast protein." ;
  rdfs:subClassOf obo:VO_0000856 .

obo:VO_0000340 a rdfs:Class ;
  rdfs:label "intramuscular route" ;
  rdfs:comment "A route of administration that inject the material(such as vaccines, allergens) directly into a muscle." ;
  rdfs:subClassOf obo:VO_0000574 .

obo:VO_0016659 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix] Box of 1 by Orifarm Leverkus" ;
  rdfs:subClassOf obo:VO_0016625 .

obo:VO_0016934 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 2 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Adt Booster]" ;
  rdfs:subClassOf obo:VO_0016933 , obo:VO_0017396 .

obo:VO_0002752 a rdfs:Class ;
  rdfs:label "obsolete E2 from Western equine encephalomyelitis virus" ;
  rdfs:comment "A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" .

obo:VO_0007264 a rdfs:Class ;
  rdfs:label "anti-idiotypic mAb MK2-23+BCG vaccine" ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0007657 .

obo:VO_0020737 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0001519 , obo:VO_0017679 .

obo:VO_0019265 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0019821 .

obo:VO_0005109 a rdfs:Class ;
  rdfs:label "SARS rMA15-ΔE vaccine" ;
  rdfs:comment "A SARS recombinant vector vaccine that is made from  recombinant MA15 virulent mouse-adapted SARS-CoV (MA15) background of E-deleted vaccine candidate  (rMA15-DeltaE)." ;
  rdfs:subClassOf obo:VO_0012183 .

obo:VO_0002115 a rdfs:Class ;
  rdfs:label "Encephalomyelitis-Influenza-West Nile Virus Eastern & Western, Killed Virus Vaccine (USDA: 13W5.20)" ;
  rdfs:comment "A horse Encephalomyelitis-Influenza-West Nile Virus vaccine that is inactivated and manufactured by Wyeth Pharmaceuticals Inc. " ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002483 , obo:VO_0007748 .

obo:VO_0018895 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 0.0857 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003501 , obo:VO_0010415 .

obo:VO_0020138 a rdfs:Class ;
  rdfs:label "mumps virus vaccine live, Jeryl Lynn strain 40000 UNT/ML Injectable Solution [Mumpsvax]" ;
  rdfs:subClassOf obo:VO_0000074 , obo:VO_0015059 .

obo:NCBITaxon_2732506 a rdfs:Class ;
  rdfs:label "Pisoniviricetes" ;
  rdfs:subClassOf obo:NCBITaxon_2732396 .

obo:VO_0000444 a rdfs:Class ;
  rdfs:label "vaccine licensing" ;
  rdfs:comment "vaccine licensing is a vaccine approval process that involves in licensing a vaccine." ;
  rdfs:subClassOf obo:VO_0000440 .

obo:VO_0019531 a rdfs:Class ;
  rdfs:label "hepatitis B surface antigen vaccine 0.04 MG/ML Injection [Heplisav-B]" ;
  rdfs:subClassOf obo:VO_0003152 , obo:VO_0015498 .

obo:VO_0000992 a rdfs:Class ;
  rdfs:label "pCN3 DNA vaccine plasmid" ;
  rdfs:comment "A DNA vaccine plasmid vector that has the plasmid label pCN3. The plasmid promoter is CMV." ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0011242 a rdfs:Class ;
  rdfs:label "IE180" ;
  rdfs:comment "To examine the response by IE180 more closely, a vaccine trial in mice with a vector DNA construct that contains the gene encoding for IE180, designated pcDNAIE180 was conducted.  Seven months after immunization with pcDNAIE180, an overall 25% of BALB/c, C3H/HeJ, and C57BL/6 mice receiving a lethal PrV challenge were protected [PubMed: 9586695]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010800 .

obo:VO_0017106 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] Box of 20 by Sanofi" ;
  rdfs:subClassOf obo:VO_0017105 .

obo:VO_0003360 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen" ;
  rdfs:subClassOf obo:VO_0003960 .

obo:VO_0001142 a rdfs:Class ;
  rdfs:label "Leishmania donovani vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000762 .

obo:VO_0005297 a rdfs:Class ;
  rdfs:label "BECC438s vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0018438 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 1" ;
  rdfs:subClassOf obo:VO_0018422 .

obo:VO_0003328 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 3 vaccine 0.05 MG/ML" ;
  rdfs:subClassOf obo:VO_0003248 .

obo:VO_0018366 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0022 MG" ;
  rdfs:subClassOf obo:VO_0003343 .

obo:VO_0019929 a rdfs:Class ;
  rdfs:label "influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine, B-Wisconsin-1-2010-like virus Prefilled Syringe [Fluzone 2012-2013 Formula]" ;
  rdfs:subClassOf obo:VO_0019923 , obo:VO_0020480 .

obo:VO_0001702 a rdfs:Class ;
  rdfs:label "Mycoplasma Gallisepticum Live Culture Vaccine (USDA: 1751.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000949 , obo:VO_0001077 , obo:VO_0001217 , obo:VO_0007748 .

obo:VO_0018075 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0018052 , obo:VO_0018155 .

obo:VO_0002202 a rdfs:Class ;
  rdfs:label "Fowl Pox-Laryngotracheitis Live Fowl Pox Vector Vaccine (USDA: 1F31.R0)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0002443 , obo:VO_0007748 .

obo:VO_0011385 a rdfs:Class ;
  rdfs:label "Actinobacillus pleuropneumoniae HS93C-Ampr" ;
  rdfs:comment "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" ;
  rdfs:subClassOf obo:VO_0001130 .

obo:VO_0007734 a rdfs:Class ;
  rdfs:label "tetanus peptide melanoma vaccine" ;
  rdfs:comment "A cancer vaccine consisting of peptides derived from melanoma-associated antigens and a modified T-cell epitope derived from tetanus toxoid. Vaccination with this agent may stimulate a host cytotoxic and helper T-cell response against tumor cells expressing melanoma-associated antigens, resulting in decreased tumor growth. This vaccine is compromised of multi-epitope melanoma peptide vaccine (12MP) and 1 tetanus peptide melanoma vaccine emulsified with GM-CSF and ISA-51 (incomplete Freund's adjuvant)." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000577 , obo:VO_0007657 .

obo:VO_0005286 a rdfs:Class ;
  rdfs:label "Mannadjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0005228 a rdfs:Class ;
  rdfs:label "ChAdV68-S vaccine" ;
  rdfs:comment "A SARS-CoV-2 Chimpanzee Adenovirus serotype 6 vector vaccine manufactured by Gritstone Oncology and the National Institute of Allergy and Infectious Diseases" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:VO_0015249 a rdfs:Class ;
  rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1000 UNT/ML" ;
  rdfs:subClassOf obo:VO_0003433 .

obo:VO_0002075 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass Type, Killed Virus Vaccine (USDA: 12M5.00)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002383 , obo:VO_0007748 .

obo:VO_0019161 a rdfs:Class ;
  rdfs:label "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000742 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0015080 a rdfs:Class ;
  rdfs:label "Fluzone 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000047 .

obo:NCBITaxon_10792 a rdfs:Class ;
  rdfs:label "Mink enteritis virus" ;
  rdfs:subClassOf obo:NCBITaxon_10786 .

obo:VO_0020578 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Influsplit] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020573 .

obo:VO_0019860 a rdfs:Class ;
  rdfs:label "influenza A virus A/Tasmania/503/2020 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Victoria/1/2020 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML / influenza B virus B/Washington/02/2019 antigen 158000000 UNT/ML Nasal Spray [FluMist Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020353 .

obo:VO_0003173 a rdfs:Class ;
  rdfs:label "Tritanrix vaccine" ;
  rdfs:comment "Active immunzation against diphtheria, tetanus, pertussis and hepatitis B (HBV) in infants from 6 weeks onwards" ;
  rdfs:subClassOf obo:VO_0000561 , obo:VO_0000712 , obo:VO_0001214 , obo:VO_0003172 .

obo:VO_0005201 a rdfs:Class ;
  rdfs:label "COVID-19 inactivated vaccine" ;
  rdfs:subClassOf obo:VO_0000712 , obo:VO_0004908 .

obo:DOID_9470 a rdfs:Class ;
  rdfs:label "bacterial meningitis"@en ;
  rdfs:comment "A meningitis that has_material_basis_in a bacterial infection."@en ;
  rdfs:subClassOf obo:DOID_104 , obo:DOID_331 .

obo:OPL_0000298 a rdfs:Class ;
  rdfs:label "Plasmodium erythrocytic schizont stage" ;
  rdfs:comment "An erythrocytic schizont stage in the Plasmodium lifecycle that occurs in the infected erythrocytes of a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000078 , obo:OPL_0000297 .

obo:VO_0004729 a rdfs:Class ;
  rdfs:label "FP-AI-H5(H5N1) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:OPL_0000307 a rdfs:Class ;
  rdfs:label "Plasmodium zygote stage" ;
  rdfs:comment "A zygote stage in the Plasmodium lifecycle that occurs in the midgut of the mosquito vector where a microgamete and a macrogamete fertilizes each other to produce a diploid cell." ;
  rdfs:subClassOf obo:OPL_0000181 , obo:UBERON_0000106 .

obo:VO_0015049 a rdfs:Class ;
  rdfs:label "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 25000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML Injection [M-M-R II]" ;
  rdfs:subClassOf obo:VO_0015048 .

obo:VO_0002868 a rdfs:Class ;
  rdfs:label "Salmonella Typhimurium asd/rfc mutant vaccine" ;
  rdfs:comment "An rfc mutant, in combination with an asd mutation, is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ;
  rdfs:subClassOf obo:VO_0002507 .

obo:VO_0020472 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003855 , obo:VO_0020280 .

obo:VO_0015705 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 1" ;
  rdfs:subClassOf obo:VO_0015570 , obo:VO_0015788 .

obo:VO_0007049 a rdfs:Class ;
  rdfs:label "TBC-CEA-Contaminated W/ BVDV vaccine" ;
  rdfs:comment "A cancer vaccine consisting of a recombinant vector encoding the tumor-associated carcinoembryonic antigen (CEA) that is‚Äö√†√∂‚àö¬ßcontaminated‚Äö√†√∂‚àö¬ßwith bovine viral diarrhea virus (BVDV). The carcinoembryonic antigen (CEA) is a prevalent tumor marker expressed by a number of different cancers such as colorectal, breast, lung and ovarian carcinomas; vaccination with vaccinia virus genetically engineered to express‚Äö√†√∂‚àö¬ßCEA‚Äö√†√∂‚àö¬ßmay generate antitumoral T-cell responses.‚Äö√†√∂‚àö¬ßBVDV‚Äö√†√∂‚àö¬ßis an RNA pestivirus that may contaminate vaccines due to its presence in fetal calf serum used as a growth supplement in the tissue culture of mammalian cells used in vaccine production." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0007657 .

obo:VO_0020294 a rdfs:Class ;
  rdfs:label "yellow fever virus strain 17D-204 live antigen 2000 UNT/ML Injection" ;
  rdfs:subClassOf obo:VO_0001220 , obo:VO_0003371 .

obo:VO_0020587 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [VAXIGRIP]" ;
  rdfs:subClassOf obo:VO_0020538 , obo:VO_0020876 .

obo:VO_0003489 a rdfs:Class ;
  rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010305 , obo:VO_0010415 .

obo:VO_0019648 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Kansas/14/2017 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2019-2020]" ;
  rdfs:subClassOf obo:VO_0000578 , obo:VO_0020343 .

obo:VO_0010187 a rdfs:Class ;
  rdfs:label "influenza A monovalent (H5N1), adjuvanted, National stockpile 2013" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 .

obo:VO_0010315 a rdfs:Class ;
  rdfs:label "influenza A virus A/Slovenia/2903/2015 (H1N1) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003498 , obo:VO_0010297 .

obo:VO_0002363 a rdfs:Class ;
  rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Haemophilus Somnus-Mannheimia Haemolytica Bacterin" ;
  rdfs:subClassOf obo:VO_0002357 .

obo:VO_0007082 a rdfs:Class ;
  rdfs:label "PR-151 Peptide Vaccine" ;
  rdfs:comment "A tumor-specific peptide encoded by patient-specific mutant p53 oncogene with potential immunostimulatory properties. The peptide (LPTGQDL) contains a frame shift mutation at amino acid position 134. It was used to pulse dendritic cells, which are then used in the adoptive immunotherapy setting and may stimulate the host immune system to mount a specific cytotoxic T lymphocyte response against tumor cells expressing the p35 mutation." ;
  rdfs:subClassOf obo:VO_0000577 , obo:VO_0005486 , obo:VO_0007657 .

obo:VO_0016089 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution [HBvaxPRO] Box of 50 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015871 .

obo:VO_0002126 a rdfs:Class ;
  rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.29)" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000712 , obo:VO_0001220 , obo:VO_0002393 , obo:VO_0007748 .

obo:VO_0002665 a rdfs:Class ;
  rdfs:label "znuA from Salmonella Typhimurium" ;
  rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001421 .

obo:VO_0001512 a rdfs:Class ;
  rdfs:label "Riemerella anatipestifer vaccine" ;
  rdfs:comment "Vaccine that protects against Riemerella anatipestifer infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0003704 a rdfs:Class ;
  rdfs:label "Fluarix Quadrivalent 2017-2018 Injectable Product" ;
  rdfs:subClassOf obo:VO_0003703 .

obo:VO_0015086 a rdfs:Class ;
  rdfs:label "influenza B virus antigen" ;
  rdfs:subClassOf obo:VO_0000919 .

obo:VO_0003124 a rdfs:Class ;
  rdfs:label "obsolete Fluogen" .

obo:VO_0002459 a rdfs:Class ;
  rdfs:label "bovine parainfluenza 3 vaccine-Leptospira Pomona vaccine" ;
  rdfs:subClassOf obo:VO_0000391 , obo:VO_0000563 , obo:VO_0000990 , obo:VO_0001507 .

obo:OPL_0000247 a rdfs:Class ;
  rdfs:label "hepatic merozoite stage" ;
  rdfs:comment "A merozoite stage in the Plasmodium lifecycle that occurs in the hepatocyte of a vertebrate host." ;
  rdfs:subClassOf obo:OPL_0000036 .

obo:VO_0021103 a rdfs:Class ;
  rdfs:label "influenza A virus A/Darwin/11/2021 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Delaware/55/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Singapore/INFTT-16-0610/2016 antigen 0.03 MG/ML / influenza B virus B/Singapore/WUH4618/2021 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010415 .

obo:VO_0019199 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000578 , obo:VO_0004673 , obo:VO_0010432 .

obo:NCBITaxon_32524 a rdfs:Class ;
  rdfs:label "Amniota" ;
  rdfs:subClassOf obo:NCBITaxon_117571 .

obo:VO_0000012 a rdfs:Class ;
  rdfs:label "vaccine-induced B cell mediated immunity" ;
  rdfs:subClassOf obo:VO_0010462 .

obo:NCBITaxon_1392 a rdfs:Class ;
  rdfs:label "Bacillus anthracis" ;
  rdfs:subClassOf obo:NCBITaxon_1386 .

obo:VO_0017319 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / Haemophilus B Conjugate Vaccine / tetanus toxoid vaccine, inactivated Injectable Solution [Hibdt]" ;
  rdfs:subClassOf obo:VO_0017318 .

obo:VO_0016698 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 20 UNT" ;
  rdfs:subClassOf obo:VO_0003455 .

obo:VO_0019170 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 4 UNT/ML Injection [Tdvax]" ;
  rdfs:subClassOf obo:VO_0019169 , obo:VO_0019463 .

obo:OPL_0000207 a rdfs:Class ;
  rdfs:label "Plasmodium falciparum erythrocytic trophozoite stage" ;
  rdfs:comment "An erythrocytic trophozoite stage in the Plasmodium falciparum life cycle that occurs in erythrocytes of a human host." ;
  rdfs:subClassOf obo:OPL_0000243 , obo:OPL_0000251 , obo:OPL_0000304 .

obo:VO_0002744 a rdfs:Class ;
  rdfs:label "nef from Simian Immunodeficiency Virus" ;
  rdfs:comment "A SIV nef mutant is attenuated in rhesus monkeys and induces protection from challenge with wild type SIV" ;
  rdfs:subClassOf obo:VO_0000048 , obo:VO_0001445 .

obo:VO_0004228 a rdfs:Class ;
  rdfs:label "cancer vaccine using E7 protein of human papillomavirus 16 and Quil-A" ;
  rdfs:comment "Gene name: E7" ;
  rdfs:subClassOf obo:VO_0000534 , obo:VO_0005488 , obo:VO_0007657 .

obo:VO_0015886 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10" ;
  rdfs:subClassOf obo:VO_0015619 , obo:VO_0016003 .

obo:VO_0007112 a rdfs:Class ;
  rdfs:label "tetravalent RNA-lipoplex cancer vaccine" ;
  rdfs:comment "A RNA-lipoplex (RNA-LIP)-based cancer vaccine containing four naked ribonucleic acid (RNA)-drug products (DPs) RBL001.1, RBL002.2, RBL003.1, and RBL004.1 encoding the four melanoma-associated antigens (MAAs), the cancer-testis antigen NY-ESO-1, the human melanoma-associated antigen A3 (MAGE-A3), tyrosinase, and putative tyrosine-protein phosphatase (TPTE), encapsulated in liposomes, with potential antineoplastic activity. Upon intravenous administration of the tetravalent RNA-lipoplex cancer vaccine BNT111, the liposomes protect the RNA from degradation in the bloodstream, travel to the spleen and are taken up by antigen-presenting cells (APCs). The RNA is translocated to the cytoplasm and translated into the four tumor-associated proteins. The expressed proteins are processed and the human leukocyte antigen (HLA)-peptide complexes are presented to the immune system. This results in the production of various pro-inflammatory cytokines and induces antigen-specific CD8+ and CD4+ T-cell responses against the four selected MAAs NY-ESO-1, MAGE-A3, tyrosinase, and TPTE." ;
  rdfs:subClassOf obo:VO_0000422 , obo:VO_0000534 , obo:VO_0007657 .

obo:VO_0011046 a rdfs:Class ;
  rdfs:label "FlaA from C. jejuni 81-176" ;
  rdfs:comment "Mice were immunized intranasally with two doses of 3 to 50 microgram of MBP-FlaA.  The protective efficacies of a 50 microgram of MBP-FlaA plus LT(R192G) dose against disease symptoms and intestinal colonization were 81.1 and 84%, respectively. When mice which had been immunized with 50 microgram of MBP-FlaA plus LT(R192G) intranasally were challenged orally with 8 x 10(10), 8 x 10(9), or 8 x 10(8) cells of strain 81-176, the protective efficacies against intestinal colonization at 7 days postinfection were 71.4, 71.4, and 100%, respectively [PubMed: 10531231]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010765 .

obo:VO_0021087 a rdfs:Class ;
  rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.006 MG/ML / hepatitis B surface antigen vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000362 , obo:VO_0000561 , obo:VO_0000712 , obo:VO_0000738 , obo:VO_0000746 , obo:VO_0001214 , obo:VO_0010437 , obo:VO_0010439 , obo:VO_0010444 , obo:VO_0010447 .

obo:VO_0005803 a rdfs:Class ;
  rdfs:label "Giardia lamblia vaccine encoding a-enolase" ;
  rdfs:comment "A Live attenuated vaccine encoding a-enolase that immunizes against Giardi lamblia trophozoite." ;
  rdfs:subClassOf obo:VO_0001083 .

obo:NCBITaxon_11039 a rdfs:Class ;
  rdfs:label "Western equine encephalitis virus" ;
  rdfs:subClassOf obo:NCBITaxon_11019 .

obo:VO_0018843 a rdfs:Class ;
  rdfs:label "oral" ;
  rdfs:subClassOf obo:VO_0015061 .

obo:VO_0020726 a rdfs:Class ;
  rdfs:label "BCG, Live, Connaught Strain 81 MG Injectable Solution [ImmuCyst] Box of 1 by Alliance" ;
  rdfs:subClassOf obo:VO_0020725 .

obo:VO_0001040 a rdfs:Class ;
  rdfs:label "fowlpox virus vaccine vector" ;
  rdfs:comment "an Avipox virus vaccine vector that uses a fowlpox virus as the vector" ;
  rdfs:subClassOf obo:VO_0001143 .

obo:VO_0015197 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix] Box of 1" ;
  rdfs:subClassOf obo:VO_0015204 , obo:VO_0015280 .

obo:VO_0018449 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Prefilled Syringe [Pneumovax II] Box of 20" ;
  rdfs:subClassOf obo:VO_0018425 .

obo:UBERON_0000062 a rdfs:Class ;
  rdfs:label "organ" ;
  rdfs:comment "Anatomical structure that performs a specific function or group of functions [WP]." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:VO_0003777 a rdfs:Class ;
  rdfs:label "Flulaval Quadrivalent 2018-2019 vaccine Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0003774 .

obo:VO_0010864 a rdfs:Class ;
  rdfs:label "VP35 from Zaire ebolavirus" ;
  rdfs:comment "VP35 expressed from alphavirus replicons induced a protective immune response in C57BL/6 mice when challenged with Ebola virus Zaire [PubMed: 11485406]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010761 .

obo:VO_0000604 a rdfs:Class ;
  rdfs:label "Mycoplasma vaccine" ;
  rdfs:comment "Vaccine that protects against Mycoplasma bacterial infection." ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000165 .

obo:VO_0020427 a rdfs:Class ;
  rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution Box of 10" ;
  rdfs:subClassOf obo:VO_0020469 .

obo:VO_0018501 a rdfs:Class ;
  rdfs:label "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0018426 .

obo:NCBITaxon_12080 a rdfs:Class ;
  rdfs:label "Poliovirus 1" ;
  rdfs:subClassOf obo:NCBITaxon_138950 .

obo:VO_0016341 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0015939 .

obo:OBI_1110034 a rdfs:Class ;
  rdfs:label "antigen"@en ;
  rdfs:comment "A material entity that has the antigen role."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0012384 a rdfs:Class ;
  rdfs:label "OspA" ;
  rdfs:comment "Mice immunized with recombinant OspA protein were protected from challenge with Borrelia burgdorferi [PubMed: 8168958]." ;
  rdfs:subClassOf obo:VO_0012368 .

obo:VO_0015541 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Suspension [Fendrix]" ;
  rdfs:subClassOf obo:VO_0003416 .

obo:VO_0015134 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 50 UNT/ML Injectable Solution [Vaqta]" ;
  rdfs:subClassOf obo:VO_0015133 , obo:VO_0015301 .

obo:VO_0003938 a rdfs:Class ;
  rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.08 MG/ML" ;
  rdfs:subClassOf obo:VO_0003303 .

obo:NCBITaxon_9224 a rdfs:Class ;
  rdfs:label "Psittacidae" ;
  rdfs:subClassOf obo:NCBITaxon_3073809 .

obo:IAO_0000310 a rdfs:Class ;
  rdfs:label "document"@en ;
  rdfs:comment "A collection of information content entities intended to be understood together as a whole"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:NCBITaxon_2732092 a rdfs:Class ;
  rdfs:label "Shotokuvirae" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:VO_0007656 a rdfs:Class ;
  rdfs:label "preventive cancer vaccine" ;
  rdfs:comment "Cancer vaccine that prevents cancer formation and development." ;
  rdfs:subClassOf obo:VO_0000177 , obo:VO_0000455 .

obo:VO_0019210 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus A/Cambodia/e0826360/2020 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Victoria/2570/2019 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML / influenza B virus B/Victoria/705/2018 antigen 0.03 MG/ML Prefilled Syringe [Fluad Quadrivalent 2021-2022]" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0020312 .

obo:VO_0016945 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 LFU/ML / tetanus toxoid vaccine, inactivated 10 LFU/ML Injectable Suspension by Iaf Biovac" ;
  rdfs:subClassOf obo:VO_0016944 .

obo:VO_0016763 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 50 LFU/ML Injectable Solution" ;
  rdfs:subClassOf obo:VO_0016703 .

obo:VO_0018041 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 2 (MEF-1) 200000 CELLS/ML" ;
  rdfs:subClassOf obo:VO_0003836 .

obo:VO_0020169 a rdfs:Class ;
  rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) Injectable Suspension [Ipol]" ;
  rdfs:subClassOf obo:VO_0000054 , obo:VO_0020168 .

obo:VO_0000514 a rdfs:Class ;
  rdfs:label "typhoid-paratyphoid vaccine" ;
  rdfs:comment "a Salmonella vaccine against both typhoid caused by S. typhi and paratyphoid caused by S. paratyphi." ;
  rdfs:subClassOf obo:VO_0000768 .

obo:VO_0002829 a rdfs:Class ;
  rdfs:label "Edwardsiella ictaluri crp mutant vaccine" ;
  rdfs:comment "A crp mutant is attenuated in zebrafish and catfish that were immunized intramuscularly and intracoelomically, respectively. Six weeks after immunization, both zebrafish and catfish were protected from challenge with wild type E. ictaluri" ;
  rdfs:subClassOf obo:VO_0001521 .

obo:VO_0010478 a rdfs:Class ;
  rdfs:label "licensed human francisella tularensis vaccine" ;
  rdfs:comment "Francisella tularensis vaccine that is licensed for use in humans." ;
  rdfs:subClassOf obo:VO_0000152 , obo:VO_0000635 .

obo:VO_0005342 a rdfs:Class ;
  rdfs:label "ChAd-triCoV/Mac vaccine" ;
  rdfs:comment "A SARS-CoV-2 replication deficient chimpanzee adenovirus 68 vector vaccine expressing the spike, nucleocapsid and RNA polymerase proteins." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005200 .

obo:VO_0020223 a rdfs:Class ;
  rdfs:label "SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 OMICRON (BA.4/BA.5) 0.025 MG/ML" ;
  rdfs:subClassOf obo:VO_0020498 .

obo:VO_0016173 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 1 by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0015892 , obo:VO_0015894 .

obo:VO_0015965 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Suspension [Engerix-B] Box of 250" ;
  rdfs:subClassOf obo:VO_0015642 , obo:VO_0015643 , obo:VO_0015733 , obo:VO_0015739 , obo:VO_0016049 .

obo:VO_0001392 a rdfs:Class ;
  rdfs:label "Trypanosoma cruzi PAR2 protein vaccine" ;
  rdfs:comment "A T. cruzi subunit vaccine that uses T. cruzi PAR2 protein as protective antigen." ;
  rdfs:subClassOf obo:VO_0001385 .

obo:VO_0006021 a rdfs:Class ;
  rdfs:label "Human Rabies vaccine from human diploid cell culture" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010448 .

obo:VO_0007130 a rdfs:Class ;
  rdfs:label "Ovapuldencel-T Vaccine" ;
  rdfs:comment "A cancer vaccine consisting of autologous dendritic cells (DCs) loaded with autologous, lethally irradiated cancer cells and mixed with the cytokine granulocyte-macrophage colony stimulating factor (GM-CSF), with potential immunostimulatory and antineoplastic activities. Upon vaccination, ovapuldencel-T may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against the repertoire of tumor associated antigens (TAAs) found in the irradiated cancer cells. GM-CSF enhances the activation of dendritic cells (DCs) and promotes antigen presentation to both B- and T-lymphocytes." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005493 , obo:VO_0007657 .

obo:VO_0018879 a rdfs:Class ;
  rdfs:label "influenza A virus A/Nebraska/14/2019 (H1N1) antigen 0.03 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010297 , obo:VO_0010415 .

obo:VO_0004623 a rdfs:Class ;
  rdfs:label "rDEV-re6 (H5) vaccine" ;
  rdfs:subClassOf obo:VO_0000642 .

obo:VO_0005206 a rdfs:Class ;
  rdfs:label "Matrix-M vaccine adjuvant" ;
  rdfs:comment "A saponin vaccine adjuvant comprised of 40 nm nanoparticles composed of Quillaja saponins, cholesterol and phospholipid." ;
  rdfs:subClassOf obo:VO_0001267 .

obo:VO_0016464 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 3 by Gerke" ;
  rdfs:subClassOf obo:VO_0015976 .

obo:VO_0003225 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 2 vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003284 , obo:VO_0010453 .

obo:OPL_0000269 a rdfs:Class ;
  rdfs:label "Plasmodium microgametocyte" ;
  rdfs:comment "A Plasmodium gametocyte that is a male gametocyte of Plasmodium and found either in the bloodstream of a vertebrate host or midgut of a mosquito vector. The microgametocyte is a precursor cell of the microgamete" ;
  rdfs:subClassOf obo:NCBITaxon_5820 , obo:OPL_0000267 .

obo:VO_0010774 a rdfs:Class ;
  rdfs:label "VEE Virus protein" ;
  rdfs:subClassOf obo:VO_0010754 .

obo:VO_0016108 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Solution Box of 50 by Merck" ;
  rdfs:subClassOf obo:VO_0015996 .

obo:VO_0018129 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Solution" ;
  rdfs:subClassOf obo:VO_0000731 , obo:VO_0001220 .

obo:VO_0017377 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injectable Solution [Dt Wellcovax]" ;
  rdfs:subClassOf obo:VO_0018786 .

obo:VO_0010329 a rdfs:Class ;
  rdfs:label "influenza A virus A/Victoria/361/2011 (H3N2) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003501 , obo:VO_0010299 .

obo:VO_0017659 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0003398 .

obo:VO_0005470 a rdfs:Class ;
  rdfs:label "Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus, Haemophilus b Conjugate (Meningococcal Protein Conjugate), and Hepatitis B (Recombinant) Vaccine." ;
  rdfs:subClassOf obo:VO_0000195 , obo:VO_0000455 , obo:VO_0000561 , obo:VO_0000563 , obo:VO_0000712 , obo:VO_0000732 , obo:VO_0001214 , obo:VO_0010435 , obo:VO_0010436 , obo:VO_0010445 , obo:VO_0010447 .

obo:VO_0016150 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Sanofi" ;
  rdfs:subClassOf obo:VO_0015886 .

obo:VO_0003715 a rdfs:Class ;
  rdfs:label "Afluria 2015-2016 vaccine" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000006 , obo:VO_0000578 .

obo:VO_0000314 a rdfs:Class ;
  rdfs:label "pSG2 DNA vaccine plasmid" ;
  rdfs:subClassOf obo:VO_0000435 .

obo:VO_0018160 a rdfs:Class ;
  rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 1400 PFU/ML Injectable Solution Box of 50" ;
  rdfs:subClassOf obo:VO_0018143 .

obo:VO_0002068 a rdfs:Class ;
  rdfs:label "Bursal Disease-Newcastle Disease Killed Virus Vaccine (USDA: 12G5.43)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0000712 , obo:VO_0002365 , obo:VO_0007748 .

obo:VO_0019406 a rdfs:Class ;
  rdfs:label "Bacillus anthracis strain V770-NP1-R antigens 0.1 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0010291 , obo:VO_0010434 .

obo:VO_0005351 a rdfs:Class ;
  rdfs:label "IN-B009 vaccine" ;
  rdfs:comment "A SARS-CoV-2 subunit vaccine by HK inno.N Corporation" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0005202 .

obo:VO_0007297 a rdfs:Class ;
  rdfs:label "Autologous GM-CSF-Secreting Lethally Irradiated Leukemia Cell Vaccine" ;
  rdfs:comment "An autologous cancer vaccine composed of lethally irradiated leukemia cells that are genetically modified to secrete the immunostimulatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Upon intradermal injection, the autologous GM-CSF-secreting lethally irradiated leukemia cell vaccine secretes GM-CSF. In turn, GM-CSF may stimulate the immune system to attack tumor cells by enhancing the activation of dendritic cells (DCs) and promoting antigen presentation to both B- and T-lymphocytes. In addition, GM-CSF promotes antibody-dependent cellular cytotoxicity (ADCC), and increases interleukin-2-mediated lymphokine-activated killer cell function." ;
  rdfs:subClassOf obo:VO_0000484 , obo:VO_0005487 , obo:VO_0007657 .

obo:VO_0017589 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 80 UNT/ML [Infanrix]" ;
  rdfs:subClassOf obo:VO_0017682 .

obo:VO_0016145 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [HBvaxPRO] Box of 10 by Cc" ;
  rdfs:subClassOf obo:VO_0015886 .

obo:VO_0017743 a rdfs:Class ;
  rdfs:label "acellular pertussis vaccine, inactivated 0.006 MG/ML Injectable Suspension [Covaxis] Box of 10" ;
  rdfs:subClassOf obo:VO_0017742 , obo:VO_0017751 .

obo:VO_0015660 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0015596 .

obo:VO_0016134 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [H B Vax] Box of 50 by Kohlpharma" ;
  rdfs:subClassOf obo:VO_0015884 .

obo:VO_0020672 a rdfs:Class ;
  rdfs:label "50 ML BCG, Live, Montreal Strain 4000000 ORGANISMS/ML Injectable Suspension [Bcg Medac] by Lamepro" ;
  rdfs:subClassOf obo:VO_0020669 .

obo:VO_0015160 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1.44 UNT/ML Prefilled Syringe [Havrix] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015150 .

obo:VO_0015793 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe Box of 50" ;
  rdfs:subClassOf obo:VO_0015491 .

obo:NCBITaxon_10292 a rdfs:Class ;
  rdfs:label "Herpesviridae" ;
  rdfs:subClassOf obo:NCBITaxon_548681 .

obo:VO_0017573 a rdfs:Class ;
  rdfs:label "tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur]" ;
  rdfs:subClassOf obo:VO_0017554 , obo:VO_0017555 .

obo:VO_0010299 a rdfs:Class ;
  rdfs:label "influenza A virus (H3N2) antigen vaccine" ;
  rdfs:subClassOf obo:VO_0003501 .

obo:VO_0003444 a rdfs:Class ;
  rdfs:label "vaccine foreign to USA" ;
  rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ;
  rdfs:subClassOf obo:VO_0000635 .

obo:VO_0015716 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution [Engerix B] Box of 10" ;
  rdfs:subClassOf obo:VO_0015572 , obo:VO_0015795 .

obo:VO_0020127 a rdfs:Class ;
  rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML / meningococcal polysaccharide vaccine group W-135 0.1 MG/ML / meningococcal polysaccharide vaccine group Y 0.1 MG/ML Injection [Menomune A/C/Y/W-135]" ;
  rdfs:subClassOf obo:VO_0000072 , obo:VO_0020126 .

obo:VO_0004217 a rdfs:Class ;
  rdfs:label "Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine-Haemophilus Parasuis Bacterin (USDA: 49Q9.20)" ;
  rdfs:subClassOf obo:VO_0000563 , obo:VO_0001217 , obo:VO_0001802 , obo:VO_0003535 .

obo:VO_0001014 a rdfs:Class ;
  rdfs:label "obsolete bacterial vaccine organism live attenuated" ;
  rdfs:comment "A live attenuated quality of a bacterial vaccine strain. " .

obo:VO_0015109 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension Box of 1" ;
  rdfs:subClassOf obo:VO_0015105 , obo:VO_0015278 .

obo:VO_0018264 a rdfs:Class ;
  rdfs:label "rabies virus vaccine flury-lep strain Injectable Suspension [Rabipur]" ;
  rdfs:subClassOf obo:VO_0018271 .

obo:VO_0001496 a rdfs:Class ;
  rdfs:label "Equine rotavirus vaccine" ;
  rdfs:comment "viral vaccine that is used to protect against Equine rotavirus infection" ;
  rdfs:subClassOf obo:VO_0000001 , obo:VO_0000658 .

obo:OBI_0000086 a rdfs:Class ;
  rdfs:label "reagent role"@en ;
  rdfs:comment "A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer."@en ;
  rdfs:subClassOf obo:OBI_0003610 .

obo:VO_0017109 a rdfs:Class ;
  rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 40 UNT/ML Injectable Suspension [Td-Pur] Box of 10" ;
  rdfs:subClassOf obo:VO_0017108 , obo:VO_0017114 , obo:VO_0017574 .

obo:VO_0010943 a rdfs:Class ;
  rdfs:label "EltB" ;
  rdfs:comment "LT is a hetero-oligomeric AB5 type enterotoxin composed of a 27 kDa A subunit with toxic ADP ribosyl transferase activity and a stable noncovalent-linked pentamer of 11.6 kDa B subunits. ETEC infection and colonization of the small intestine, and the production of LT, causes acute diarrhea that can be fatal without intervention [PubMed: 17188785]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010766 .

obo:VO_0019308 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.12 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML Prefilled Syringe" ;
  rdfs:subClassOf obo:VO_0020004 .

obo:VO_0000881 a rdfs:Class ;
  rdfs:label "Equity vaccine" ;
  rdfs:comment "Equity Oestrus Control Vaccine for Horses is prepared from an analogue of gonadotropin releasing factor (GnRF) linked to a carrier protein. It has an adjuvant that enhances the level and duration of the immune response to GnRF with minimal injection site reactivity. It is used as an aid in the control of oestrus and oestrus-related behaviour in fillies and mares not intended for breeding." ;
  rdfs:subClassOf obo:VO_0000409 , obo:VO_0000455 , obo:VO_0000759 .

obo:VO_0017217 a rdfs:Class ;
  rdfs:label "50 ML tetanus toxoid vaccine, inactivated 1.5 UNT/ML Injectable Solution [Tetanol] Box of 1" ;
  rdfs:subClassOf obo:VO_0017216 , obo:VO_0017218 , obo:VO_0017468 .

obo:VO_0002465 a rdfs:Class ;
  rdfs:label "Parvovirus-Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae-Leptospira CanicolaGrippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002461 .

obo:NCBITaxon_641 a rdfs:Class ;
  rdfs:label "Vibrionaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:VO_0001355 a rdfs:Class ;
  rdfs:label "emulsion vaccine adjuvant" ;
  rdfs:subClassOf obo:VO_0000580 .

obo:VO_0017713 a rdfs:Class ;
  rdfs:label "0.5 ML Pertussis Vaccine 0.016 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0017779 .

obo:VO_0000084 a rdfs:Class ;
  rdfs:label "Pentacel vaccine" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000714 , obo:VO_0000744 , obo:VO_0010163 .

obo:VO_0015970 a rdfs:Class ;
  rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B] Box of 25" ;
  rdfs:subClassOf obo:VO_0003265 .

obo:VO_0003574 a rdfs:Class ;
  rdfs:label "ProQuad vaccine 0.5 ML Injection" ;
  rdfs:subClassOf obo:VO_0003573 .

obo:VO_0010937 a rdfs:Class ;
  rdfs:label "Env Gp160" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010767 .

obo:VO_0012395 a rdfs:Class ;
  rdfs:label "FBP54" ;
  rdfs:comment "Mice subcutaneously or orally immunized with FBP54 survived significantly longer following the challenge with S. pyogenes than did nonimmunized mice [PubMed: 11159987]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0012357 .

obo:VO_0020431 a rdfs:Class ;
  rdfs:label "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] by Glaxosmithkline" ;
  rdfs:subClassOf obo:VO_0020408 .

obo:VO_0003600 a rdfs:Class ;
  rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen" ;
  rdfs:comment "RXAUI: 9198755" ;
  rdfs:subClassOf obo:VO_0015084 .

obo:VO_0011163 a rdfs:Class ;
  rdfs:label "NP from Lake Victoria marburgvirus" ;
  rdfs:comment "Nonhuman primates (cynomolgus macaques) were inoculated with VEE replicons expressing MBGV GP and/or NP and challenged with MGBV.  MBGV NP afforded incomplete (partial) protection, sufficient to prevent death but not disease in two of three macaques [PubMed: 9813200 ]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010769 .

obo:VO_0011217 a rdfs:Class ;
  rdfs:label "CS from P. berghei str. ANKA" ;
  rdfs:comment "Researchers produced a prototypic malaria vaccine based on a highly versatile self-assembling polypeptide nanoparticle (SAPN) platform that can repetitively display antigenic epitopes. Researchers used this platform to display a tandem repeat of the B cell immunodominant repeat epitope (DPPPPNPN)(2)D of the malaria parasite Plasmodium berghei circumsporozoite (CS) protein. Administered in saline, without the need for a heterologous adjuvant, the SAPN construct P4c-Mal conferred a long-lived, protective immune response to mice with a broad range of genetically distinct immune backgrounds including the H-2(b), H-2(d), and H-2(k) alleles. Mice were protected against an initial challenge of parasites up to 6 mo after the last immunization or for up to 15 mo against a second challenge after an initial challenge of parasites had successfully been cleared.  [PubMed: 19915055]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0015475 .

obo:VO_0016184 a rdfs:Class ;
  rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix B] Box of 1 by Mtk" ;
  rdfs:subClassOf obo:VO_0015900 .

obo:VO_0018095 a rdfs:Class ;
  rdfs:label "0.5 ML MEASLES VIRUS VACCINE,LIVE ATTENUATED 1400 PFU/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 7000 PFU/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 1400 PFU/ML Prefilled Syringe [Priorix] Box of 1" ;
  rdfs:subClassOf obo:VO_0018094 , obo:VO_0018097 , obo:VO_0018230 .

obo:VO_0002460 a rdfs:Class ;
  rdfs:label "Parvovirus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ;
  rdfs:subClassOf obo:VO_0002461 .

obo:VO_0005365 a rdfs:Class ;
  rdfs:label "Zymosan vaccine adjuvant" ;
  rdfs:comment "A carbohydrate vaccine adjuvant that polysaccharide prepared from the cell wall of Saccaromyces cerevisiae (bakers' yeast)." ;
  rdfs:subClassOf obo:VO_0001359 .

obo:VO_0015609 a rdfs:Class ;
  rdfs:label "0.5 ML HEPATITIS B VIRUS SUBTYPE ADW2 HBSAG SURFACE PROTEIN ANTIGEN 0.02 MG/ML Injectable Suspension [Engerix B] Box of 50" ;
  rdfs:subClassOf obo:VO_0015557 , obo:VO_0015592 , obo:VO_0015656 .

obo:VO_0015796 a rdfs:Class ;
  rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injectable Solution Box of 100" ;
  rdfs:subClassOf obo:VO_0015492 .

obo:VO_0001621 a rdfs:Class ;
  rdfs:label "Bronchitis Mass & Conn Types, Live Virus Vaccine (USDA: 1231.14)" ;
  rdfs:subClassOf obo:VO_0000446 , obo:VO_0000455 , obo:VO_0001220 , obo:VO_0001502 , obo:VO_0007748 .

obo:VO_0010431 a rdfs:Class ;
  rdfs:label "human influenza virus vaccine 2018-2019" ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0010415 , obo:VO_0010457 .

obo:VO_0019690 a rdfs:Class ;
  rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Injectable Suspension" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0000578 , obo:VO_0001236 , obo:VO_0010415 .

obo:VO_0016786 a rdfs:Class ;
  rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML Injectable Suspension [Td-Impfstoff Merieux] by Sanofi" ;
  rdfs:subClassOf obo:VO_0016727 .

obo:VO_0018014 a rdfs:Class ;
  rdfs:label "poliomyelitis virus type 1 brunhilde 80 UNT/ML" ;
  rdfs:subClassOf obo:VO_0018011 .

obo:VO_0002830 a rdfs:Class ;
  rdfs:label "Edwardsiella tarda aroC mutant vaccine" ;
  rdfs:comment "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" ;
  rdfs:subClassOf obo:VO_0002506 .

obo:VO_0020567 a rdfs:Class ;
  rdfs:label "0.5 ML influenza A virus (H1N1) antigen 0.03 MG/ML Injectable Suspension [Grippeimpfstoff Ratiopharm] Box of 10 by Mylan" ;
  rdfs:subClassOf obo:VO_0020566 .

obo:VO_0018862 a rdfs:Class ;
  rdfs:label "influenza A virus A/Brisbane/02/2018 (H1N1) antigen 0.09 MG/ML" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0001045 a rdfs:Class ;
  rdfs:label "APMV-3 vaccine vector" ;
  rdfs:comment "a viral vaccine vector that uses an avian paramyxovirus strain" ;
  rdfs:subClassOf obo:VO_0000610 .

obo:VO_0010998 a rdfs:Class ;
  rdfs:label "GroEL from Salmonella spp." ;
  rdfs:comment "Researchers evaluated the immunogenicity and protective efficacy of GroEL of Salmonella enterica serovar Typhi against lethal infection by S. typhi Ty2 in mice with or without adjuvants.  Immunization of mice with GroEL-alone, GroEL + alum, and GroEL + CFA provided 70, 50 and 80% protection, respectively, against lethal challenge by S. typhi in mice.  The present study shows that GroEL forms an ideal candidate molecule to develop a recombinant protein based vaccine against human typhoid [PubMed: 19851830]." ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010776 .

obo:VO_0000981 a rdfs:Class ;
  rdfs:label "Porcilis Pesti vaccine" ;
  rdfs:subClassOf obo:VO_0000206 , obo:VO_0000455 , obo:VO_0001012 .

obo:VO_0017792 a rdfs:Class ;
  rdfs:label "Pertussis Vaccine 15000000000 UNT/ML Injectable Suspension Box of 5" ;
  rdfs:subClassOf obo:VO_0017791 .

obo:VO_0004197 a rdfs:Class ;
  rdfs:label "pcDNA3-LiP0 vaccine" ;
  rdfs:subClassOf obo:VO_0012159 .

obo:DOID_686 a rdfs:Class ;
  rdfs:label "liver carcinoma"@en ;
  rdfs:comment "A liver cancer that has_material_basis_in epithelial cells."@en ;
  rdfs:subClassOf obo:DOID_305 , obo:DOID_3571 .

obo:VO_0004063 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae PhpA-79 protein vaccine" ;
  rdfs:subClassOf obo:VO_0000675 .

obo:VO_0010027 a rdfs:Class ;
  rdfs:label "Leishmania  major P36" ;
  rdfs:comment "A P36 protein that is part of Leishmania  major" ;
  rdfs:subClassOf obo:VO_0001232 , obo:VO_0010835 .

obo:VO_0016875 a rdfs:Class ;
  rdfs:label "diphtheria toxoid vaccine, inactivated 0.2 LFU/ML Injectable Solution by Connaught" ;
  rdfs:subClassOf obo:VO_0016757 .

obo:VO_0017872 a rdfs:Class ;
  rdfs:label "Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.004 MG" ;
  rdfs:subClassOf obo:VO_0015063 .

obo:VO_0018439 a rdfs:Class ;
  rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 1.15 MG/ML Injectable Solution [Pneumovax 23] Box of 10" ;
  rdfs:subClassOf obo:VO_0018422 .

obo:VO_0000731 a rdfs:Class ;
  rdfs:label "Measles-Mumps-Rubella vaccine" ;
  rdfs:comment "A Measles-Mumps vaccine that also protects against infection with  Rubella virus." ;
  rdfs:subClassOf obo:VO_0000455 , obo:VO_0000736 , obo:VO_0010441 , obo:VO_0010442 , obo:VO_0010450 .

obo:VO_0003514 a rdfs:Class ;
  rdfs:label "influenza virus vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain" ;
  rdfs:subClassOf obo:VO_0000362 , obo:VO_0000455 , obo:VO_0001176 , obo:VO_0003498 , obo:VO_0010415 .

obo:VO_0005439 a rdfs:Class ;
  rdfs:label "passive vaccine" ;
  rdfs:comment "A vaccine that is made of immune globulin and used to immunize an individual against some disease(s)." ;
  rdfs:subClassOf obo:VO_0005505 .

obo:VO_0004917 a rdfs:Class ;
  rdfs:label "vaccine specific interleukin-4 response" ;
  rdfs:comment "vaccine-induced T-helper 2 type immune response that is indicated by the presence of interleukin-4 production" ;
  rdfs:subClassOf obo:VO_0000101 .

obo:BFO_0000067 a rdf:Property ;
  rdfs:label "contains process"@en ;
  rdfs:comment "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000179 a rdf:Property ;
  rdfs:label "BFO OWL specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ;
  rdfs:range xsd:string .

obo:BFO_0000180 a rdf:Property ;
  rdfs:label "BFO CLIF specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ;
  rdfs:range xsd:string .

obo:IAO_0000111 a rdf:Property ;
  rdfs:label "editor preferred term"@en ;
  rdfs:comment "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000112 a rdf:Property ;
  rdfs:label "example of usage"@en ;
  rdfs:comment "A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold."@en ;
  rdfs:range xsd:string .

obo:IAO_0000113 a rdf:Property ;
  rdfs:label "in branch"@en ;
  rdfs:comment "An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet."@en ;
  rdfs:range xsd:string .

obo:IAO_0000114 a rdf:Property ;
  rdfs:label "has curation status"@en ;
  rdfs:range xsd:string .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "definition"@en ;
  rdfs:comment "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "editor note"@en ;
  rdfs:comment "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ;
  rdfs:range xsd:string .

obo:IAO_0000117 a rdf:Property ;
  rdfs:label "term editor"@en ;
  rdfs:comment "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ;
  rdfs:range xsd:string .

obo:IAO_0000118 a rdf:Property ;
  rdfs:label "alternative label"@en ;
  rdfs:comment "A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like."@en ;
  rdfs:range xsd:string .

obo:IAO_0000119 a rdf:Property ;
  rdfs:label "definition source"@en ;
  rdfs:comment "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ;
  rdfs:range xsd:string .

obo:IAO_0000231 a rdf:Property ;
  rdfs:label "has obsolescence reason"@en ;
  rdfs:comment "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ;
  rdfs:range xsd:string .

obo:IAO_0000232 a rdf:Property ;
  rdfs:label "curator note"@en ;
  rdfs:comment "An administrative note of use for a curator but of no use for a user"@en ;
  rdfs:range xsd:string .

obo:IAO_0000233 a rdf:Property ;
  rdfs:label "term tracker item"@en ;
  rdfs:comment "An IRI or similar locator for a request or discussion of an ontology term."@en ;
  rdfs:range xsd:string .

obo:IAO_0000234 a rdf:Property ;
  rdfs:label "ontology term requester"@en ;
  rdfs:comment "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition."@en ;
  rdfs:range xsd:string .

obo:IAO_0000411 a rdf:Property ;
  rdfs:label "is denotator type"@en ;
  rdfs:comment "Relates an class defined in an ontology, to the type of it's denotator"@en ;
  rdfs:range xsd:string .

obo:IAO_0000412 a rdf:Property ;
  rdfs:label "imported from"@en ;
  rdfs:comment "For external terms/classes, the ontology from which the term was imported"@en ;
  rdfs:range xsd:string .

obo:IAO_0000424 a rdf:Property ;
  rdfs:label "expand expression to"@en ;
  rdfs:comment "A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en ;
  rdfs:range xsd:string .

obo:IAO_0000425 a rdf:Property ;
  rdfs:label "expand assertion to"@en ;
  rdfs:comment "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en ;
  rdfs:range xsd:string .

obo:IAO_0000426 a rdf:Property ;
  rdfs:label "first order logic expression"@en ;
  rdfs:range xsd:string .

obo:IAO_0000427 a rdf:Property ;
  rdfs:label "antisymmetric property"@en ;
  rdfs:comment "Use boolean value xsd:true to indicate that the property is an antisymmetric property"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OMO_0001001 .

obo:IAO_0000589 a rdf:Property ;
  rdfs:label "OBO foundry unique label"@en ;
  rdfs:comment "An alternative name for a class or property which is unique across the OBO Foundry."@en ;
  rdfs:range xsd:string .

obo:IAO_0000596 a rdf:Property ;
  rdfs:label "has ID digit count"@en ;
  rdfs:comment "Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix\" annotation property value concatenated with an integer in the id range (left padded with \"0\"s to make this many digits)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000597 a rdf:Property ;
  rdfs:label "has ID range allocated to"@en ;
  rdfs:comment "Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms"@en ;
  rdfs:range xsd:string .

obo:IAO_0000598 a rdf:Property ;
  rdfs:label "has ID policy for"@en ;
  rdfs:comment "Relating an ontology used to record id policy to the ontology namespace whose policy it manages"@en ;
  rdfs:range xsd:string .

obo:IAO_0000599 a rdf:Property ;
  rdfs:label "has ID prefix"@en ;
  rdfs:comment "Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with \"0\"s to make this many digits) to construct an ID for a term being created."@en ;
  rdfs:range xsd:string .

obo:IAO_0000600 a rdf:Property ;
  rdfs:label "elucidation"@en ;
  rdfs:range xsd:string .

obo:IAO_0000601 a rdf:Property ;
  rdfs:label "has associated axiom(nl)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000602 a rdf:Property ;
  rdfs:label "has associated axiom(fol)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000603 a rdf:Property ;
  rdfs:label "is allocated id range"@en ;
  rdfs:comment "Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. \"IAO_0020000-IAO_0020999\""@en ;
  rdfs:range xsd:string .

obo:IAO_0000700 a rdf:Property ;
  rdfs:label "has ontology root term"@en ;
  rdfs:comment "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ;
  rdfs:range xsd:string .

obo:IAO_0006011 a rdf:Property ;
  rdfs:label "may be identical to"@en ;
  rdfs:comment "A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged."@en ;
  rdfs:range xsd:string .

obo:IAO_0006012 a rdf:Property ;
  rdfs:label "scheduled for obsoletion on or after"@en ;
  rdfs:comment "Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date."@en ;
  rdfs:range xsd:dateTime .

obo:IAO_0010000 a rdf:Property ;
  rdfs:label "has axiom label"@en ;
  rdfs:range xsd:string .

obo:IAO_0100001 a rdf:Property ;
  rdfs:label "term replaced by"@en ;
  rdfs:comment "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
  rdfs:range xsd:string .

obo:OBI_0001847 a rdf:Property ;
  rdfs:label "ISA alternative term"@en ;
  rdfs:comment "An alternative term used by the ISA tools project (http://isa-tools.org)."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:OBI_9991118 a rdf:Property ;
  rdfs:label "IEDB alternative term" ;
  rdfs:comment "An alternative term used by the IEDB."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:OGG_0000000006 a rdf:Property ;
  rdfs:label "NCBI GeneID"@en ;
  rdfs:comment "A GeneID in the NCBI Gene database " ;
  rdfs:range xsd:string .

obo:OGG_0000000007 a rdf:Property ;
  rdfs:label "NCBI LocusTag"@en ;
  rdfs:comment "the NCBI LocusTag name of a gene " ;
  rdfs:range xsd:string .

obo:OGG_0000000009 a rdf:Property ;
  rdfs:label "modification date"@en ;
  rdfs:comment "a date of content modification" ;
  rdfs:range xsd:string .

obo:OGG_0000000015 a rdf:Property ;
  rdfs:label "organism NCBITaxon ID"@en ;
  rdfs:comment "The NCBITaxon ontology ID of an organism." ;
  rdfs:range xsd:string .

obo:OGG_0000000017 a rdf:Property ;
  rdfs:label "chromosome ID of gene"@en ;
  rdfs:comment "A chromosome ID where a gene is located." ;
  rdfs:range xsd:string .

obo:OGG_0000000018 a rdf:Property ;
  rdfs:label "type of gene"@en ;
  rdfs:comment "an annotation property that specifies the type of a gene" ;
  rdfs:range xsd:string .

obo:OGG_0000000019 a rdf:Property ;
  rdfs:label "nomenclature status"@en ;
  rdfs:comment "an annotation property that specifies a nomenclature status" ;
  rdfs:range xsd:string .

obo:OGG_0000000030 a rdf:Property ;
  rdfs:label "has PubMed association"@en ;
  rdfs:comment "An annotation property that represents a gene's association with PubMed publication(s). " ;
  rdfs:range xsd:string .

obo:OMO_0001001 a rdf:Property ;
  rdfs:label "logical characteristic of object property" ;
  rdfs:comment "This is an annotation used on an object property to indicate a logical characterstic beyond what is possible in OWL." ;
  rdfs:range xsd:string .

obo:OMO_0002000 a rdf:Property ;
  rdfs:label "defined by construct" ;
  rdfs:comment "Links an annotation property to a SPARQL CONSTRUCT query which is meant to provide semantics for a shortcut relation." ;
  rdfs:range xsd:string .

obo:OMO_0003000 a rdf:Property ;
  rdfs:label "abbreviation" ;
  rdfs:comment "A synonym type for describing abbreviations or initalisms" ;
  rdfs:range xsd:string .

obo:OMO_0003001 a rdf:Property ;
  rdfs:label "ambiguous synonym" ;
  rdfs:comment "A synonym type for describing ambiguous synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003002 a rdf:Property ;
  rdfs:label "dubious synonym" ;
  rdfs:comment "A synonym type for describing dubious synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003003 a rdf:Property ;
  rdfs:label "layperson synonym" ;
  rdfs:comment "A synonym type for describing layperson or colloquial synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003004 a rdf:Property ;
  rdfs:label "plural form" ;
  rdfs:comment "A synonym type for describing pluralization synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003005 a rdf:Property ;
  rdfs:label "UK spelling synonym" ;
  rdfs:comment "A synonym type for describing UK spelling variants" ;
  rdfs:range xsd:string .

obo:OMO_0003006 a rdf:Property ;
  rdfs:label "misspelling" ;
  rdfs:comment "A synonym type for common misspellings" ;
  rdfs:range xsd:string .

obo:OMO_0003007 a rdf:Property ;
  rdfs:label "misnomer" ;
  rdfs:comment "A synonym type for misnomers, i.e., a synonym that is not technically correct but is commonly used anyway" ;
  rdfs:range xsd:string .

obo:OMO_0003008 a rdf:Property ;
  rdfs:label "previous name" ;
  rdfs:comment "A synonym type for names that have been used as primary labels in the past." ;
  rdfs:range xsd:string .

obo:OMO_0003009 a rdf:Property ;
  rdfs:label "legal name" ;
  rdfs:comment "A synonym type for the legal entity name" ;
  rdfs:range xsd:string .

obo:OMO_0003010 a rdf:Property ;
  rdfs:label "International Nonproprietary Name" ;
  rdfs:comment "The International Nonproprietary Name (INN) is a standardize name for a pharmaceutical drug or active ingredient issued by the World Health Organization (WHO) meant to address the issues with country- or language-specific brand names. These are issued in several languages, including English, Latin, French, Russian, Spanish, Arabic, and Chinese." ;
  rdfs:range xsd:string .

obo:OMO_0003011 a rdf:Property ;
  rdfs:label "latin term" ;
  rdfs:comment "A synonym type for describing Latin term synonyms." ;
  rdfs:range xsd:string .

obo:OMO_0003012 a rdf:Property ;
  rdfs:label "acronym" ;
  rdfs:comment "A synonym type for describing abbreviations that are a part of the full name's words, such as initialisms or alphabetisms." ;
  rdfs:range xsd:string .

obo:OMO_0004000 a rdf:Property ;
  rdfs:label "has symbol" ;
  rdfs:comment "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity." ;
  rdfs:range xsd:string .

obo:RO_0000053 a rdf:Property ;
  rdfs:label "has characteristic"@en ;
  rdfs:comment "Inverse of characteristic_of"@en ;
  rdfs:range obo:BFO_0000020 .

obo:RO_0000080 a rdf:Property ;
  rdfs:label "quality of"@en ;
  rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000081 a rdf:Property ;
  rdfs:label "role of"@en ;
  rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000092 a rdf:Property ;
  rdfs:label "disposition of"@en ;
  rdfs:comment "inverse of has disposition" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0001001 a rdf:Property ;
  rdfs:label "derives into"@en ;
  rdfs:comment "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001015 a rdf:Property ;
  rdfs:label "location of"@en ;
  rdfs:comment "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001900 a rdf:Property ;
  rdfs:label "temporal interpretation" ;
  rdfs:comment "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0002000 a rdf:Property ;
  rdfs:label "2D boundary of"@en ;
  rdfs:comment "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002009 a rdf:Property ;
  rdfs:label "cell expresses" ;
  rdfs:comment "A relation that applies between a cell(c) and a gene(g) , where the process of 'transcription, DNA templated (GO_0006351)' is occuring in in cell c and that process has input gene g." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002292 .

obo:RO_0002086 a rdf:Property ;
  rdfs:label "ends after"@en ;
  rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002091 a rdf:Property ;
  rdfs:label "starts during"@en ;
  rdfs:comment "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002092 a rdf:Property ;
  rdfs:label "happens during"@en ;
  rdfs:comment "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))"@en ;
  rdfs:seeAlso <https://wiki.geneontology.org/Happens_during> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002093 , obo:RO_0002091 .

obo:RO_0002093 a rdf:Property ;
  rdfs:label "ends during"@en ;
  rdfs:comment "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). "@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002161 a rdf:Property ;
  rdfs:label "never in taxon" ;
  rdfs:comment "x never in taxon T if and only if T is a class, and x does not instantiate the class expression \"in taxon some T\". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002172 .

obo:RO_0002171 a rdf:Property ;
  rdfs:label "mutually spatially disjoint with"@en ;
  rdfs:comment "A is mutually_spatially_disjoint_with B if both A and B are classes, and there exists no p such that p is part_of some A and p is part_of some B." ;
  rdfs:seeAlso obo:RO_0002163 , <https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002420 .

obo:RO_0002172 a rdf:Property ;
  rdfs:label "taxonomic class assertion"@en ;
  rdfs:comment "An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002420 .

obo:RO_0002175 a rdf:Property ;
  rdfs:label "present in taxon"@en ;
  rdfs:comment "S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S" ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002172 .

obo:RO_0002204 a rdf:Property ;
  rdfs:label "gene product of"@en ;
  rdfs:comment "definition \"x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x\"" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002330 .

obo:RO_0002205 a rdf:Property ;
  rdfs:label "has gene product"@en ;
  rdfs:comment "x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002330 .

obo:RO_0002206 a rdf:Property ;
  rdfs:label "expressed in"@en ;
  rdfs:comment "x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002330 .

obo:RO_0002222 a rdf:Property ;
  rdfs:label "temporally related to"@en ;
  rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002245 a rdf:Property ;
  rdfs:label "over-expressed in" ;
  rdfs:comment "g is over-expressed in t iff g is expressed in t, and the expression level of g is increased relative to some background." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002206 .

obo:RO_0002246 a rdf:Property ;
  rdfs:label "under-expressed in" ;
  rdfs:comment "g is under-expressed in t iff g is expressed in t, and the expression level of g is decreased relative to some background." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002206 .

obo:RO_0002260 a rdf:Property ;
  rdfs:label "has biological role" ;
  rdfs:comment "c has-biological-role r iff c has-role r and r is a biological role (CHEBI:24432)" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000087 .

obo:RO_0002261 a rdf:Property ;
  rdfs:label "has application role" ;
  rdfs:comment "c has-application-role r iff c has-role r and r is an application role (CHEBI:33232)" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000087 .

obo:RO_0002262 a rdf:Property ;
  rdfs:label "has chemical role" ;
  rdfs:comment "c has-chemical-role r iff c has-role r and r is a chemical role (CHEBI:51086)" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000087 .

obo:RO_0002291 a rdf:Property ;
  rdfs:label "ubiquitously expressed in"@en ;
  rdfs:comment "x is ubiquitously expressed in y if and only if x is expressed in y, and the majority of cells in y express x" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002206 .

obo:RO_0002293 a rdf:Property ;
  rdfs:label "ubiquitously expresses"@en ;
  rdfs:comment "inverse of ubiquiotously expressed in" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002292 .

obo:RO_0002314 a rdf:Property ;
  rdfs:label "characteristic of part of"@en ;
  rdfs:comment "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/reflexivity/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002502 .

obo:RO_0002320 a rdf:Property ;
  rdfs:label "evolutionarily related to"@en ;
  rdfs:comment "A relationship that holds via some environmental process" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002330 a rdf:Property ;
  rdfs:label "genomically related to"@en ;
  rdfs:comment "holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002350 a rdf:Property ;
  rdfs:label "member of"@en ;
  rdfs:comment "is member of is a mereological relation between a item and a collection." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002410 a rdf:Property ;
  rdfs:label "causally related to"@en ;
  rdfs:comment "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002416 a rdf:Property ;
  rdfs:label "logical macro assertion"@en ;
  rdfs:comment "An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/shortcut-relations/> ;
  rdfs:range xsd:string .

obo:RO_0002420 a rdf:Property ;
  rdfs:label "logical macro assertion on a class"@en ;
  rdfs:comment "A logical macro assertion whose domain is an IRI for a class" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002416 .

obo:RO_0002421 a rdf:Property ;
  rdfs:label "logical macro assertion on a property"@en ;
  rdfs:comment "A logical macro assertion whose domain is an IRI for a property" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002416 .

obo:RO_0002422 a rdf:Property ;
  rdfs:label "logical macro assertion on an object property"@en ;
  rdfs:comment "Used to annotate object properties to describe a logical meta-property or characteristic of the object property." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002421 .

obo:RO_0002502 a rdf:Property ;
  rdfs:label "depends on" ;
  rdfs:seeAlso obo:BFO_0000169 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002503 a rdf:Property ;
  rdfs:label "towards" ;
  rdfs:comment "q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002502 .

obo:RO_0002510 a rdf:Property ;
  rdfs:label "transcribed from" ;
  rdfs:comment "x is transcribed from y if and only if x is synthesized from template y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002330 .

obo:RO_0002511 a rdf:Property ;
  rdfs:label "transcribed to" ;
  rdfs:comment "inverse of transcribed from" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002330 .

obo:RO_0002512 a rdf:Property ;
  rdfs:label "ribosomal translation of" ;
  rdfs:comment "x is the ribosomal translation of y if and only if a ribosome reads x through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002330 .

obo:RO_0002513 a rdf:Property ;
  rdfs:label "ribosomally translates to" ;
  rdfs:comment "inverse of ribosomal translation of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002330 .

obo:RO_0002601 a rdf:Property ;
  rdfs:label "logical macro assertion involving identity" ;
  rdfs:comment "A shortcut relationship that holds between two entities based on their identity criteria" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002416 .

obo:RO_0002602 a rdf:Property ;
  rdfs:label "in approximate one to one relationship with" ;
  rdfs:comment "A shortcut relationship between two entities x and y1, such that the intent is that the relationship is functional and inverse function, but there is no guarantee that this property holds." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002601 .

obo:RO_0002604 a rdf:Property ;
  rdfs:label "is opposite of" ;
  rdfs:comment "x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x)." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002602 .

obo:RO_0004017 a rdf:Property ;
  rdfs:label "realizable has basis in" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0004023 a rdf:Property ;
  rdfs:label "causal relationship with disease as subject" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0040035 , obo:RO_0002410 .

obo:RO_0004096 a rdf:Property ;
  rdfs:label "DEPRECATED inheres in"@en ;
  rdfs:comment "DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0004097 a rdf:Property ;
  rdfs:label "DEPRECATED bearer of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0040035 a rdf:Property ;
  rdfs:label "disease relationship" ;
  rdfs:comment "This relation groups  relations between diseases and any other kind of entity." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:UBPROP_0000001 a rdf:Property ;
  rdfs:label "external_definition" ;
  rdfs:range xsd:string .

obo:UBPROP_0000002 a rdf:Property ;
  rdfs:label "axiom_lost_from_external_ontology" ;
  rdfs:range xsd:string .

obo:UBPROP_0000003 a rdf:Property ;
  rdfs:label "homology_notes" ;
  rdfs:range xsd:string .

obo:UBPROP_0000007 a rdf:Property ;
  rdfs:label "has_relational_adjective" ;
  rdfs:range xsd:string .

obo:UBPROP_0000008 a rdf:Property ;
  rdfs:label "taxon_notes" ;
  rdfs:range xsd:string .

obo:UBPROP_0000011 a rdf:Property ;
  rdfs:label "development_notes" ;
  rdfs:range xsd:string .

obo:UBPROP_0000012 a rdf:Property ;
  rdfs:label "external_ontology_notes" ;
  rdfs:range xsd:string .

obo:UBPROP_0000202 a rdf:Property ;
  rdfs:label "fma_set_term" ;
  rdfs:range xsd:string .

obo:VO_0000016 a rdf:Property ;
  rdfs:label "has vaccine conjugate protein" ;
  rdfs:comment "A type of 'has vaccine component' relation that specifies a vaccine conjugate protein for a specific vaccine" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:VO_0000520 .

obo:VO_0000138 a rdf:Property ;
  rdfs:label "has bacterial vaccine vector" ;
  rdfs:comment "A type of 'has vaccine vector' relation that specifies a bacterial vaccine vector" ;
  rdfs:range obo:NCBITaxon_2 ;
  rdfs:subPropertyOf obo:VO_0000530 .

obo:VO_0000270 a rdf:Property ;
  rdfs:label "has vaccine contraindication" ;
  rdfs:comment "A relation that specifies contraindication of a vaccine." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0000281 a rdf:Property ;
  rdfs:label "has viral vaccine vector" ;
  rdfs:comment "A type of 'has vaccine vector' that is specifically for viral vaccine vector" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:VO_0000530 .

obo:VO_0000369 a rdf:Property ;
  rdfs:label "has DNA vaccine plasmid" ;
  rdfs:comment "A 'has vaccine component' relation that specifies the plasmid used for development of a particular DNA vaccine. " ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:VO_0000520 .

obo:VO_0000445 a rdf:Property ;
  rdfs:label "infection_of" ;
  rdfs:comment "A relation between a disorder and an infectious pathogen." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0000462 a rdf:Property ;
  rdfs:label "induced by vaccination of" ;
  rdfs:comment "An object property that specifies a process that is induced by vaccination of a vaccine" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0000476 a rdf:Property ;
  rdfs:label "has DNA vaccine antigen gene" ;
  rdfs:comment "A 'has vaccine component' relation that specifies a gene inserted to DNA vaccine plasmid for development of a particular DNA vaccine, and this gene encodes for a protein antigen. " ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:VO_0000520 .

obo:VO_0000524 a rdf:Property ;
  rdfs:label "has vaccine antigen" ;
  rdfs:comment "An object property that specifies a vaccine antigen" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0000527 a rdf:Property ;
  rdfs:label "has vaccine protective antigen" ;
  rdfs:comment "A type of 'has vaccine antigen' relation that is specifically for vaccine protective antigen component" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:VO_0000524 .

obo:VO_0000529 a rdf:Property ;
  rdfs:label "has vaccine adjuvant" ;
  rdfs:comment "A type of 'has vaccine component' relation that is specifically for vaccine adjuvant component" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:VO_0000520 .

obo:VO_0000538 a rdf:Property ;
  rdfs:label "has vaccine preservative" ;
  rdfs:comment "A 'has vaccine component' relation that is specifically used for vaccine preservative" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:VO_0000520 .

obo:VO_0000608 a rdf:Property ;
  rdfs:label "DNA vaccine expresses protein antigen" ;
  rdfs:comment "An 'expresses' relation that specifies a relation between a DNA vaccine and a  protein antigen to be expressed by the DNA vaccine. " ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002292 .

obo:VO_0000638 a rdf:Property ;
  rdfs:label "obsolete vaccinates" ;
  rdfs:comment "A relation between a vaccine instance and an organism type such that if the vaccine instance is given to an instance of the organism by the process vaccination, then it changes the organism's disposition to have an immune response against a disease." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0000711 a rdf:Property ;
  rdfs:label "obsolete has_vaccine_allergen" ;
  rdfs:comment "has_vaccine_allegen is a relation that specifies an allegen to a vaccine." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0000799 a rdf:Property ;
  rdfs:label "vaccine organism has mutation" ;
  rdfs:comment "An object property that represents a mutational relation between a vaccine organism and another material (e.g., gene or protein). the mutated material initially exists in the original wildtype organism. " ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0000818 a rdf:Property ;
  rdfs:label "has vaccine virmugen" ;
  rdfs:comment "An object property that specifies a relation between a vaccine and a vaccine virmugen. " ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0000894 a rdf:Property ;
  rdfs:label "has subunit vaccine protective antigen" ;
  rdfs:comment "A 'has subunit vaccine antigen' relation that indicates the antigen is protective." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:VO_0000525 .

obo:VO_0000908 a rdf:Property ;
  rdfs:label "is_distributed_by" ;
  rdfs:comment "A relation that specifies a company that distributes a product (e.g., vaccine). The company is very likely not the manufacturer of the product." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0001818 a rdf:Property ;
  rdfs:label "VIOLIN vaccine ID" ;
  rdfs:comment "An annotation property that represents a matched vaccine identifier used in the VIOLIN database." ;
  rdfs:range xsd:string .

obo:VO_0003099 a rdf:Property ;
  rdfs:label "trade name" ;
  rdfs:comment "An annotation property that represents the trade name of a product." ;
  rdfs:range xsd:string .

obo:VO_0003127 a rdf:Property ;
  rdfs:label "has prime vaccine" ;
  rdfs:comment "An object property that represents a relation between a vaccine with a prime-boost schedule and a vaccine used for priming." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0003146 a rdf:Property ;
  rdfs:label "has vaccine active ingredient" ;
  rdfs:comment "An annotation property that represents the active ingredient of a vaccine." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:VO_0003147 .

obo:VO_0003147 a rdf:Property ;
  rdfs:label "has vaccine ingredient" ;
  rdfs:comment "An annotation property that represents the vaccine ingredient of a vaccine. Such an ingredient may not be active." ;
  rdfs:range xsd:string .

obo:VO_0003151 a rdf:Property ;
  rdfs:label "vaccine dose annotation" ;
  rdfs:comment "An annotation property that describes the dose information of a vaccine" ;
  rdfs:range xsd:string .

obo:VO_0003158 a rdf:Property ;
  rdfs:label "obsolete vaccine proper name" ;
  rdfs:comment "An annotation property that represents the proper name of a vaccine, which is defined in an official way such as one defined by FDA." ;
  rdfs:range xsd:string .

obo:VO_0003159 a rdf:Property ;
  rdfs:label "obsolete vaccine manufacturer" ;
  rdfs:comment "An annotation property that represents the manufacturer of a vaccine" ;
  rdfs:range xsd:string .

obo:VO_0003160 a rdf:Property ;
  rdfs:label "FDA vaccine indications" ;
  rdfs:comment "An annotation property that represents the indications of a vaccine defined by the USA FDA." ;
  rdfs:range xsd:string .

obo:VO_0003161 a rdf:Property ;
  rdfs:label "vaccine package insert PDF URL" ;
  rdfs:comment "An annotation property that represents a URL of the package insert PDF document of a licensed vaccine" ;
  rdfs:range xsd:string .

obo:VO_0003162 a rdf:Property ;
  rdfs:label "vaccine STN" ;
  rdfs:comment "An annotation property that indicate the number that is generated by FDA based on a request from an applicant of a product licensing." ;
  rdfs:range xsd:string .

obo:VO_0003198 a rdf:Property ;
  rdfs:label "RxNorm ID" ;
  rdfs:range xsd:string .

obo:VO_0003557 a rdf:Property ;
  rdfs:label "obsolete has Protegen id" ;
  rdfs:range xsd:string .

obo:VO_0003558 a rdf:Property ;
  rdfs:label "obsolete has Protegen annotation" ;
  rdfs:range xsd:string .

obo:VO_0003560 a rdf:Property ;
  rdfs:label "RxNorm Preferred Name" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:VO_0004909 a rdf:Property ;
  rdfs:label "obsolete immunizes against disease process" ;
  rdfs:comment "A shortcut object property that represents a relation between a vaccine and a disease process where the vaccine immunizes a host against a disease process." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0005279 a rdf:Property ;
  rdfs:label "RxNorm Synonym" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:VO_0005328 a rdf:Property ;
  rdfs:label "VAC adjuvant ID" ;
  rdfs:comment "An identifier assigned by the Vaccine Adjuvant Compendium (VAC: https://vac.niaid.nih.gov/)" ;
  rdfs:range xsd:string .

obo:VO_0005431 a rdf:Property ;
  rdfs:label "vaccine antigen annotation" ;
  rdfs:comment "An annotation property that represents the annotated information about the antigens used for a specific vaccine." ;
  rdfs:range xsd:string .

obo:VO_0005432 a rdf:Property ;
  rdfs:label "obsolete vaccine preparation annotation" ;
  rdfs:range xsd:string .

obo:VO_0005433 a rdf:Property ;
  rdfs:label "vaccine response annotation" ;
  rdfs:range xsd:string .

obo:VO_0005438 a rdf:Property ;
  rdfs:label "CVX code" ;
  rdfs:comment "An annotation property that refers to a specific CVX ID." ;
  rdfs:range xsd:string .

obo:VO_0005481 a rdf:Property ;
  rdfs:label "capable of blocking transmission (of life cycle)" ;
  rdfs:comment "A relation between a material entity  and a parasite where the material entity causes some process against some parasite such that transmitting to additional hosts or vectors." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_0005500 a rdf:Property ;
  rdfs:label "obsolete status of vaccine development" ;
  rdfs:comment "An annotation property that shows the status of vaccine developmeint including: clinical trial, research, licensed, or Emergency Use Authorization (EUA)." ;
  rdfs:range xsd:string .

obo:VO_0010151 a rdf:Property ;
  rdfs:label "OMOP concept ID" ;
  rdfs:comment "An annotation property that represents an identifier of RxNorm or RxNorm extension concept assigned by OMOP." ;
  rdfs:range xsd:string .

obo:VO_0010152 a rdf:Property ;
  rdfs:label "RxNorm OMOP extension ID" ;
  rdfs:comment "An annotation property that represents an identifier of RxNorm extension term assigned by OMOP." ;
  rdfs:range xsd:string .

obo:VO_0015021 a rdf:Property ;
  rdfs:label "has drug supplier" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:VO_1000000 a rdf:Property ;
  rdfs:label "CVX full vaccine name" ;
  rdfs:comment "An annotation property that refers to full vaccine name in CVX code set." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:VO_1000001 a rdf:Property ;
  rdfs:label "CVX short description" ;
  rdfs:comment "An annotation property that refers to short description in CVX code set." ;
  rdfs:range xsd:string .

<http://purl.obolibrary.org/obo/ncbitaxon#has_rank> a rdf:Property ;
  rdfs:label "has_rank" ;
  rdfs:range xsd:string .

obo:IAO_0000409 a rdfs:Class ;
  rdfs:label "denotator type"@en ;
  rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000410 a obo:IAO_0000409 ;
  rdfs:label "universal"@en .

obo:IAO_0000420 a obo:IAO_0000409 ;
  rdfs:label "defined class"@en ;
  rdfs:comment "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en .

obo:IAO_0000421 a obo:IAO_0000409 ;
  rdfs:label "named class expression"@en ;
  rdfs:comment "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en .

obo:VO_0015077 a rdfs:Class ;
  rdfs:label "drug brand name" ;
  rdfs:comment "An information content entity that specifies a family of drug products containing a specific active ingredient." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0010458 a obo:VO_0015077 ;
  rdfs:label "Comirnaty 2023-2024" .

obo:VO_0010459 a obo:VO_0015077 ;
  rdfs:label "Spikevax 2023-2024" .

obo:VO_0015341 a obo:VO_0015077 ;
  rdfs:label "Vaqta" .

obo:VO_0015342 a obo:VO_0015077 ;
  rdfs:label "Epaxal" .

obo:VO_0015343 a obo:VO_0015077 ;
  rdfs:label "Havpur" .

obo:VO_0015344 a obo:VO_0015077 ;
  rdfs:label "Havrix" .

obo:VO_0015345 a obo:VO_0015077 ;
  rdfs:label "Vivaxim" .

obo:VO_0015346 a obo:VO_0015077 ;
  rdfs:label "Hepatyrix" .

obo:VO_0015347 a obo:VO_0015077 ;
  rdfs:label "ViATIM" .

obo:VO_0015348 a obo:VO_0015077 ;
  rdfs:label "Hav Sorbat Ssw" .

obo:VO_0015357 a obo:VO_0015077 ;
  rdfs:label "AC Vax" .

obo:VO_0015358 a obo:VO_0015077 ;
  rdfs:label "Acel Imune" .

obo:VO_0015359 a obo:VO_0015077 ;
  rdfs:label "Acel P Lederle" .

obo:VO_0015360 a obo:VO_0015077 ;
  rdfs:label "Acel-P" .

obo:VO_0015361 a obo:VO_0015077 ;
  rdfs:label "Act-HIB DTP" .

obo:VO_0015362 a obo:VO_0015077 ;
  rdfs:label "ActHIB" .

obo:VO_0015363 a obo:VO_0015077 ;
  rdfs:label "ACWY Vax" .

obo:VO_0015364 a obo:VO_0015077 ;
  rdfs:label "Adacel" .

obo:VO_0015365 a obo:VO_0015077 ;
  rdfs:label "Adt Booster" .

obo:VO_0015366 a obo:VO_0015077 ;
  rdfs:label "Adt" .

obo:VO_0015367 a obo:VO_0015077 ;
  rdfs:label "Ambirix" .

obo:VO_0015368 a obo:VO_0015077 ;
  rdfs:label "Anrix" .

obo:VO_0015369 a obo:VO_0015077 ;
  rdfs:label "Arilvax" .

obo:VO_0015370 a obo:VO_0015077 ;
  rdfs:label "Attenuvax" .

obo:VO_0015371 a obo:VO_0015077 ;
  rdfs:label "Begrivac" .

obo:VO_0015372 a obo:VO_0015077 ;
  rdfs:label "Bexsero" .

obo:VO_0015373 a obo:VO_0015077 ;
  rdfs:label "Bimmugen" .

obo:VO_0015374 a obo:VO_0015077 ;
  rdfs:label "Biothrax" .

obo:VO_0015375 a obo:VO_0015077 ;
  rdfs:label "Boostrix" .

obo:VO_0015376 a obo:VO_0015077 ;
  rdfs:label "Cervarix" .

obo:VO_0015377 a obo:VO_0015077 ;
  rdfs:label "Cervarix Grk" .

obo:VO_0015378 a obo:VO_0015077 ;
  rdfs:label "Clostet" .

obo:VO_0015379 a obo:VO_0015077 ;
  rdfs:label "Covaxis" .

obo:VO_0015380 a obo:VO_0015077 ;
  rdfs:label "Di Te Tuss Asid" .

obo:VO_0015381 a obo:VO_0015077 ;
  rdfs:label "Di Tetasorbat" .

obo:VO_0015382 a obo:VO_0015077 ;
  rdfs:label "Diftavax" .

obo:VO_0015383 a obo:VO_0015077 ;
  rdfs:label "Dipht Toxoid Asid" .

obo:VO_0015384 a obo:VO_0015077 ;
  rdfs:label "Diphtherie-Adsorbat-Impfstoff Behring" .

obo:VO_0015385 a obo:VO_0015077 ;
  rdfs:label "Dpt Merieux" .

obo:VO_0015386 a obo:VO_0015077 ;
  rdfs:label "Dpt Vaccinol" .

obo:VO_0015387 a obo:VO_0015077 ;
  rdfs:label "Dt Impfstoff" .

obo:VO_0015388 a obo:VO_0015077 ;
  rdfs:label "Dt Rix" .

obo:VO_0015389 a obo:VO_0015077 ;
  rdfs:label "Dt Vaccinol" .

obo:VO_0015390 a obo:VO_0015077 ;
  rdfs:label "Dt Wellcovax" .

obo:VO_0015391 a obo:VO_0015077 ;
  rdfs:label "Dtp Rix" .

obo:VO_0015392 a obo:VO_0015077 ;
  rdfs:label "Engerix-B" .

obo:VO_0015393 a obo:VO_0015077 ;
  rdfs:label "Enzira" .

obo:VO_0015394 a obo:VO_0015077 ;
  rdfs:label "Ervevax" .

obo:VO_0015395 a obo:VO_0015077 ;
  rdfs:label "Eurim Pharm" .

obo:VO_0015396 a obo:VO_0015077 ;
  rdfs:label "Fendrix" .

obo:VO_0015397 a obo:VO_0015077 ;
  rdfs:label "Fsme Immun" .

obo:VO_0015398 a obo:VO_0015077 ;
  rdfs:label "Gardasil" .

obo:VO_0015399 a obo:VO_0015077 ;
  rdfs:label "Gemvites" .

obo:VO_0015400 a obo:VO_0015077 ;
  rdfs:label "Gen Vax" .

obo:VO_0015401 a obo:VO_0015077 ;
  rdfs:label "H B Vax" .

obo:VO_0015402 a obo:VO_0015077 ;
  rdfs:label "H-B-Vax II" .

obo:VO_0015403 a obo:VO_0015077 ;
  rdfs:label "HBvaxPRO" .

obo:VO_0015404 a obo:VO_0015077 ;
  rdfs:label "Hepasorbat" .

obo:VO_0015405 a obo:VO_0015077 ;
  rdfs:label "Heptavax" .

obo:VO_0015406 a obo:VO_0015077 ;
  rdfs:label "Hevac B" .

obo:VO_0015407 a obo:VO_0015077 ;
  rdfs:label "HEXYON" .

obo:VO_0015408 a obo:VO_0015077 ;
  rdfs:label "Hib Dpt Merieux" .

obo:VO_0015409 a obo:VO_0015077 ;
  rdfs:label "Hibdpt Vaccinol" .

obo:VO_0015410 a obo:VO_0015077 ;
  rdfs:label "Hibdt" .

obo:VO_0015411 a obo:VO_0015077 ;
  rdfs:label "Hiberix" .

obo:VO_0015412 a obo:VO_0015077 ;
  rdfs:label "HibTITER" .

obo:VO_0015413 a obo:VO_0015077 ;
  rdfs:label "Imojev" .

obo:VO_0015414 a obo:VO_0015077 ;
  rdfs:label "Imovax" .

obo:VO_0015415 a obo:VO_0015077 ;
  rdfs:label "Imuvac" .

obo:VO_0015416 a obo:VO_0015077 ;
  rdfs:label "Infanrix" .

obo:VO_0015417 a obo:VO_0015077 ;
  rdfs:label "Infanrix Hexa" .

obo:VO_0015418 a obo:VO_0015077 ;
  rdfs:label "Infanrix-Hib" .

obo:VO_0015419 a obo:VO_0015077 ;
  rdfs:label "Invivac" .

obo:VO_0015420 a obo:VO_0015077 ;
  rdfs:label "Ipol" .

obo:VO_0015421 a obo:VO_0015077 ;
  rdfs:label "Ixiaro" .

obo:VO_0015422 a obo:VO_0015077 ;
  rdfs:label "Japanese encephalitis GCVC" .

obo:VO_0015423 a obo:VO_0015077 ;
  rdfs:label "Je-Vax" .

obo:VO_0015424 a obo:VO_0015077 ;
  rdfs:label "Jespect" .

obo:VO_0015425 a obo:VO_0015077 ;
  rdfs:label "Lt Grk" .

obo:VO_0015426 a obo:VO_0015077 ;
  rdfs:label "M-M-R II" .

obo:VO_0015427 a obo:VO_0015077 ;
  rdfs:label "M-M-RVAXPRO" .

obo:VO_0015428 a obo:VO_0015077 ;
  rdfs:label "Mastaflu" .

obo:VO_0015429 a obo:VO_0015077 ;
  rdfs:label "Menactra" .

obo:VO_0015430 a obo:VO_0015077 ;
  rdfs:label "Mencevax Acwy" .

obo:VO_0015431 a obo:VO_0015077 ;
  rdfs:label "Mengivac" .

obo:VO_0015432 a obo:VO_0015077 ;
  rdfs:label "Mengivac A + C" .

obo:VO_0015433 a obo:VO_0015077 ;
  rdfs:label "Meningitec" .

obo:VO_0015434 a obo:VO_0015077 ;
  rdfs:label "Menitorix" .

obo:VO_0015435 a obo:VO_0015077 ;
  rdfs:label "Menjugate" .

obo:VO_0015436 a obo:VO_0015077 ;
  rdfs:label "Menquadfi" .

obo:VO_0015437 a obo:VO_0015077 ;
  rdfs:label "Menveo" .

obo:VO_0015438 a obo:VO_0015077 ;
  rdfs:label "Mmr Priorix" .

obo:VO_0015439 a obo:VO_0015077 ;
  rdfs:label "Moniarix" .

obo:VO_0015440 a obo:VO_0015077 ;
  rdfs:label "Multitest Cmi" .

obo:VO_0015441 a obo:VO_0015077 ;
  rdfs:label "Mumpsvax" .

obo:VO_0015442 a obo:VO_0015077 ;
  rdfs:label "Neisvac C" .

obo:VO_0015443 a obo:VO_0015077 ;
  rdfs:label "Nimenrix" .

obo:VO_0015444 a obo:VO_0015077 ;
  rdfs:label "Pa Vaccinol" .

obo:VO_0015445 a obo:VO_0015077 ;
  rdfs:label "Pac Merieux" .

obo:VO_0015446 a obo:VO_0015077 ;
  rdfs:label "Pediacel" .

obo:VO_0015447 a obo:VO_0015077 ;
  rdfs:label "PedvaxHIB" .

obo:VO_0015448 a obo:VO_0015077 ;
  rdfs:label "Pertuvac" .

obo:VO_0015449 a obo:VO_0015077 ;
  rdfs:label "Pneumopur" .

obo:VO_0015450 a obo:VO_0015077 ;
  rdfs:label "Pneumorix" .

obo:VO_0015451 a obo:VO_0015077 ;
  rdfs:label "Pneumovax 23" .

obo:VO_0015452 a obo:VO_0015077 ;
  rdfs:label "Pneumovax II" .

obo:VO_0015453 a obo:VO_0015077 ;
  rdfs:label "Pnu-Imune" .

obo:VO_0015454 a obo:VO_0015077 ;
  rdfs:label "Polio Sabin-Rit Multi" .

obo:VO_0015455 a obo:VO_0015077 ;
  rdfs:label "Polio Sabin-S" .

obo:VO_0015456 a obo:VO_0015077 ;
  rdfs:label "Poliovaccine Ssi" .

obo:VO_0015457 a obo:VO_0015077 ;
  rdfs:label "Prevnar" .

obo:VO_0015458 a obo:VO_0015077 ;
  rdfs:label "Priorix" .

obo:VO_0015459 a obo:VO_0015077 ;
  rdfs:label "Priorix-Tetra" .

obo:VO_0015460 a obo:VO_0015077 ;
  rdfs:label "Procomvax" .

obo:VO_0015461 a obo:VO_0015077 ;
  rdfs:label "ProQuad" .

obo:VO_0015462 a obo:VO_0015077 ;
  rdfs:label "Quadracel" .

obo:VO_0015463 a obo:VO_0015077 ;
  rdfs:label "Quatro Virelon No" .

obo:VO_0015464 a obo:VO_0015077 ;
  rdfs:label "RabAvert" .

obo:VO_0015465 a obo:VO_0015077 ;
  rdfs:label "Rabipur" .

obo:VO_0015466 a obo:VO_0015077 ;
  rdfs:label "Rabivac" .

obo:VO_0015467 a obo:VO_0015077 ;
  rdfs:label "Recombivax" .

obo:VO_0015468 a obo:VO_0015077 ;
  rdfs:label "Repevax" .

obo:VO_0015469 a obo:VO_0015077 ;
  rdfs:label "Revaxis" .

obo:VO_0015470 a obo:VO_0015077 ;
  rdfs:label "Rotarix" .

obo:VO_0015477 a obo:VO_0015077 ;
  rdfs:label "RUDIVAX" .

obo:VO_0015479 a obo:VO_0015077 ;
  rdfs:label "Silgard" .

obo:VO_0015480 a obo:VO_0015077 ;
  rdfs:label "Stamaril" .

obo:VO_0015481 a obo:VO_0015077 ;
  rdfs:label "Synflorix" .

obo:VO_0015482 a obo:VO_0015077 ;
  rdfs:label "T Immun" .

obo:VO_0018810 a obo:VO_0015077 ;
  rdfs:label "T Medevax" .

obo:VO_0018811 a obo:VO_0015077 ;
  rdfs:label "T Polio Adsorbed" .

obo:VO_0018812 a obo:VO_0015077 ;
  rdfs:label "T Vaccinol" .

obo:VO_0018813 a obo:VO_0015077 ;
  rdfs:label "T Wellcovax" .

obo:VO_0018814 a obo:VO_0015077 ;
  rdfs:label "T-Immun Immuno" .

obo:VO_0018815 a obo:VO_0015077 ;
  rdfs:label "Tab Impfstoff" .

obo:VO_0018816 a obo:VO_0015077 ;
  rdfs:label "Td Impfstoff" .

obo:VO_0018817 a obo:VO_0015077 ;
  rdfs:label "Td-Impfstoff Merieux" .

obo:VO_0018818 a obo:VO_0015077 ;
  rdfs:label "Td-Pur" .

obo:VO_0018819 a obo:VO_0015077 ;
  rdfs:label "Tet Aktiv" .

obo:VO_0018820 a obo:VO_0015077 ;
  rdfs:label "Tetabulin" .

obo:VO_0018821 a obo:VO_0015077 ;
  rdfs:label "Tetamun" .

obo:VO_0018822 a obo:VO_0015077 ;
  rdfs:label "Tetanol" .

obo:VO_0018823 a obo:VO_0015077 ;
  rdfs:label "Tetanus-Impfstoff Merieux" .

obo:VO_0018824 a obo:VO_0015077 ;
  rdfs:label "Tetasorbat" .

obo:VO_0018825 a obo:VO_0015077 ;
  rdfs:label "Tetatoxoid" .

obo:VO_0018826 a obo:VO_0015077 ;
  rdfs:label "Tetravac" .

obo:VO_0018827 a obo:VO_0015077 ;
  rdfs:label "TicoVac" .

obo:VO_0018828 a obo:VO_0015077 ;
  rdfs:label "Tollwut-Impfstoff" .

obo:VO_0018829 a obo:VO_0015077 ;
  rdfs:label "Tri-Immunol Im" .

obo:VO_0018830 a obo:VO_0015077 ;
  rdfs:label "Triaxis" .

obo:VO_0018831 a obo:VO_0015077 ;
  rdfs:label "Tripacel" .

obo:VO_0018832 a obo:VO_0015077 ;
  rdfs:label "Trumenba" .

obo:VO_0018833 a obo:VO_0015077 ;
  rdfs:label "Tussoglobin" .

obo:VO_0018834 a obo:VO_0015077 ;
  rdfs:label "Twinrix" .

obo:VO_0018835 a obo:VO_0015077 ;
  rdfs:label "Twinrix Adult" .

obo:VO_0018836 a obo:VO_0015077 ;
  rdfs:label "Twinrix Paediatric" .

obo:VO_0018837 a obo:VO_0015077 ;
  rdfs:label "Typherix" .

obo:VO_0018838 a obo:VO_0015077 ;
  rdfs:label "Typhim VI" .

obo:VO_0018839 a obo:VO_0015077 ;
  rdfs:label "VACCIN GENHEVAC B" .

obo:VO_0018840 a obo:VO_0015077 ;
  rdfs:label "VACCIN RABIQUE INACTIVE MERIEUX" .

obo:VO_0018841 a obo:VO_0015077 ;
  rdfs:label "Verorab" .

obo:VO_0018842 a obo:VO_0015077 ;
  rdfs:label "Vivotif Berna" .

obo:VO_0018930 a obo:VO_0015077 ;
  rdfs:label "ACAM2000" .

obo:VO_0018931 a obo:VO_0015077 ;
  rdfs:label "ACEL-IMUNE" .

obo:VO_0018932 a obo:VO_0015077 ;
  rdfs:label "Afluria 2010-2011 Formula" .

obo:VO_0018933 a obo:VO_0015077 ;
  rdfs:label "Afluria 2011-2012 Formula" .

obo:VO_0018934 a obo:VO_0015077 ;
  rdfs:label "Afluria 2012-2013 Formula" .

obo:VO_0018935 a obo:VO_0015077 ;
  rdfs:label "Afluria 2013-2014 Formula" .

obo:VO_0018936 a obo:VO_0015077 ;
  rdfs:label "Afluria 2014-2015 Formula" .

obo:VO_0018937 a obo:VO_0015077 ;
  rdfs:label "Afluria 2015-2016" .

obo:VO_0018938 a obo:VO_0015077 ;
  rdfs:label "Afluria 2016-2017" .

obo:VO_0018939 a obo:VO_0015077 ;
  rdfs:label "Afluria 2017-2018" .

obo:VO_0018940 a obo:VO_0015077 ;
  rdfs:label "Afluria 2018-2019" .

obo:VO_0018941 a obo:VO_0015077 ;
  rdfs:label "Afluria Quadrivalent 2016-2017 Formula" .

obo:VO_0018942 a obo:VO_0015077 ;
  rdfs:label "Afluria Quadrivalent 2017-2018" .

obo:VO_0018943 a obo:VO_0015077 ;
  rdfs:label "Afluria Quadrivalent 2018-2019" .

obo:VO_0018944 a obo:VO_0015077 ;
  rdfs:label "Afluria Quadrivalent 2019-2020" .

obo:VO_0018945 a obo:VO_0015077 ;
  rdfs:label "Afluria Quadrivalent 2020-2021" .

obo:VO_0018946 a obo:VO_0015077 ;
  rdfs:label "Afluria Quadrivalent 2021-2022" .

obo:VO_0018947 a obo:VO_0015077 ;
  rdfs:label "Afluria Quadrivalent 2022-2023" .

obo:VO_0018948 a obo:VO_0015077 ;
  rdfs:label "Agriflu 2010-2011 Formula" .

obo:VO_0018949 a obo:VO_0015077 ;
  rdfs:label "Agriflu 2012-2013 Formula" .

obo:VO_0018950 a obo:VO_0015077 ;
  rdfs:label "Biavax II" .

obo:VO_0018951 a obo:VO_0015077 ;
  rdfs:label "Certiva" .

obo:VO_0018952 a obo:VO_0015077 ;
  rdfs:label "Comirnaty" .

obo:VO_0018953 a obo:VO_0015077 ;
  rdfs:label "COMVAX" .

obo:VO_0018954 a obo:VO_0015077 ;
  rdfs:label "Daptacel" .

obo:VO_0018955 a obo:VO_0015077 ;
  rdfs:label "Decavac" .

obo:VO_0018956 a obo:VO_0015077 ;
  rdfs:label "Dryvax" .

obo:VO_0018957 a obo:VO_0015077 ;
  rdfs:label "FLUAD 2015-2016" .

obo:VO_0018958 a obo:VO_0015077 ;
  rdfs:label "Fluad 2016-2017" .

obo:VO_0018959 a obo:VO_0015077 ;
  rdfs:label "Fluad 2017-2018" .

obo:VO_0018960 a obo:VO_0015077 ;
  rdfs:label "Fluad 2018-2019" .

obo:VO_0018961 a obo:VO_0015077 ;
  rdfs:label "Fluad 2019-2020" .

obo:VO_0018962 a obo:VO_0015077 ;
  rdfs:label "Fluad 2020-2021" .

obo:VO_0018963 a obo:VO_0015077 ;
  rdfs:label "Fluad Quadrivalent 2020-2021" .

obo:VO_0018964 a obo:VO_0015077 ;
  rdfs:label "Fluad Quadrivalent 2021-2022" .

obo:VO_0018965 a obo:VO_0015077 ;
  rdfs:label "Fluad Quadrivalent 2022-2023" .

obo:VO_0018966 a obo:VO_0015077 ;
  rdfs:label "Fluarix 2010-2011 Formula" .

obo:VO_0018967 a obo:VO_0015077 ;
  rdfs:label "Fluarix 2011-2012 Formula" .

obo:VO_0018968 a obo:VO_0015077 ;
  rdfs:label "Fluarix 2012-2013 Formula" .

obo:VO_0018969 a obo:VO_0015077 ;
  rdfs:label "Fluarix 2013-2014 Formula" .

obo:VO_0018970 a obo:VO_0015077 ;
  rdfs:label "Fluarix 2014-2015 Formula" .

obo:VO_0018971 a obo:VO_0015077 ;
  rdfs:label "Fluarix Quad 2014-2015 Formula" .

obo:VO_0018972 a obo:VO_0015077 ;
  rdfs:label "Fluarix Quadrivalent 2015-2016" .

obo:VO_0018973 a obo:VO_0015077 ;
  rdfs:label "Fluarix Quadrivalent 2016-2017" .

obo:VO_0018974 a obo:VO_0015077 ;
  rdfs:label "Fluarix Quadrivalent 2017-2018" .

obo:VO_0018975 a obo:VO_0015077 ;
  rdfs:label "Fluarix Quadrivalent 2018-2019" .

obo:VO_0018976 a obo:VO_0015077 ;
  rdfs:label "Fluarix Quadrivalent 2019-2020" .

obo:VO_0018977 a obo:VO_0015077 ;
  rdfs:label "Fluarix Quadrivalent 2020-2021" .

obo:VO_0018978 a obo:VO_0015077 ;
  rdfs:label "Fluarix Quadrivalent 2021-2022" .

obo:VO_0018979 a obo:VO_0015077 ;
  rdfs:label "Fluarix Quadrivalent 2022-2023" .

obo:VO_0018980 a obo:VO_0015077 ;
  rdfs:label "Flublok 2012-2013 Formula" .

obo:VO_0018981 a obo:VO_0015077 ;
  rdfs:label "Flublok 2013-2014 Formula" .

obo:VO_0018982 a obo:VO_0015077 ;
  rdfs:label "Flublok 2014-2015 Formula" .

obo:VO_0018983 a obo:VO_0015077 ;
  rdfs:label "Flublok 2015-2016" .

obo:VO_0018984 a obo:VO_0015077 ;
  rdfs:label "Flublok 2016-2017" .

obo:VO_0018985 a obo:VO_0015077 ;
  rdfs:label "Flublok 2017-2018" .

obo:VO_0018986 a obo:VO_0015077 ;
  rdfs:label "Flublok Quadrivalent 2017-2018" .

obo:VO_0018987 a obo:VO_0015077 ;
  rdfs:label "Flublok Quadrivalent 2018-2019" .

obo:VO_0018988 a obo:VO_0015077 ;
  rdfs:label "Flublok Quadrivalent 2019-2020" .

obo:VO_0018989 a obo:VO_0015077 ;
  rdfs:label "Flublok Quadrivalent 2020-2021" .

obo:VO_0018990 a obo:VO_0015077 ;
  rdfs:label "Flublok Quadrivalent 2021-2022" .

obo:VO_0018991 a obo:VO_0015077 ;
  rdfs:label "Flublok Quadrivalent 2022-2023" .

obo:VO_0018992 a obo:VO_0015077 ;
  rdfs:label "Flucelvax 2012-2013 Formula" .

obo:VO_0018993 a obo:VO_0015077 ;
  rdfs:label "Flucelvax 2013-2014 Formula" .

obo:VO_0018994 a obo:VO_0015077 ;
  rdfs:label "Flucelvax 2014-2015 Formula" .

obo:VO_0018995 a obo:VO_0015077 ;
  rdfs:label "Flucelvax 2015-2016" .

obo:VO_0018996 a obo:VO_0015077 ;
  rdfs:label "Flucelvax Quadrivalent 2016-2017" .

obo:VO_0018997 a obo:VO_0015077 ;
  rdfs:label "Flucelvax Quadrivalent 2017-2018" .

obo:VO_0018998 a obo:VO_0015077 ;
  rdfs:label "Flucelvax Quadrivalent 2018-2019" .

obo:VO_0018999 a obo:VO_0015077 ;
  rdfs:label "Flucelvax Quadrivalent 2019-2020" .

obo:VO_0019000 a obo:VO_0015077 ;
  rdfs:label "Flucelvax Quadrivalent 2020-2021" .

obo:VO_0019001 a obo:VO_0015077 ;
  rdfs:label "Flucelvax Quadrivalent 2021-2022" .

obo:VO_0019002 a obo:VO_0015077 ;
  rdfs:label "Flucelvax Quadrivalent 2022-2023" .

obo:VO_0019003 a obo:VO_0015077 ;
  rdfs:label "FluLaval 2010-2011 Formula" .

obo:VO_0019004 a obo:VO_0015077 ;
  rdfs:label "Flulaval 2011-2012 Formula" .

obo:VO_0019005 a obo:VO_0015077 ;
  rdfs:label "Flulaval 2012-2013 Formula" .

obo:VO_0019006 a obo:VO_0015077 ;
  rdfs:label "Flulaval 2013-2014 Formula" .

obo:VO_0019007 a obo:VO_0015077 ;
  rdfs:label "Flulaval 2014-2015 Formula" .

obo:VO_0019008 a obo:VO_0015077 ;
  rdfs:label "Flulaval Quad 2013-2014 Formula" .

obo:VO_0019009 a obo:VO_0015077 ;
  rdfs:label "Flulaval Quad 2014-2015 Formula" .

obo:VO_0019010 a obo:VO_0015077 ;
  rdfs:label "FluLaval Quadrivalent 2015-2016" .

obo:VO_0019011 a obo:VO_0015077 ;
  rdfs:label "Flulaval Quadrivalent 2016-2017" .

obo:VO_0019012 a obo:VO_0015077 ;
  rdfs:label "Flulaval Quadrivalent 2017-2018" .

obo:VO_0019013 a obo:VO_0015077 ;
  rdfs:label "Flulaval Quadrivalent 2018-2019" .

obo:VO_0019014 a obo:VO_0015077 ;
  rdfs:label "Flulaval Quadrivalent 2019-2020" .

obo:VO_0019015 a obo:VO_0015077 ;
  rdfs:label "Flulaval Quadrivalent 2020-2021" .

obo:VO_0019016 a obo:VO_0015077 ;
  rdfs:label "Flulaval Quadrivalent 2021-2022" .

obo:VO_0019017 a obo:VO_0015077 ;
  rdfs:label "Flulaval Quadrivalent 2022-2023" .

obo:VO_0019018 a obo:VO_0015077 ;
  rdfs:label "FluMist 2010-2011 Formula" .

obo:VO_0019019 a obo:VO_0015077 ;
  rdfs:label "Flumist 2011-2012 Formula" .

obo:VO_0019020 a obo:VO_0015077 ;
  rdfs:label "Flumist 2012-2013 Formula" .

obo:VO_0019021 a obo:VO_0015077 ;
  rdfs:label "Flumist 2014-2015 Formula" .

obo:VO_0019022 a obo:VO_0015077 ;
  rdfs:label "Flumist 2015-2016" .

obo:VO_0019023 a obo:VO_0015077 ;
  rdfs:label "Flumist Quadrivalent 2016-2017" .

obo:VO_0019024 a obo:VO_0015077 ;
  rdfs:label "Flumist Quadrivalent 2017-2018" .

obo:VO_0019025 a obo:VO_0015077 ;
  rdfs:label "Flumist Quadrivalent 2018-2019" .

obo:VO_0019026 a obo:VO_0015077 ;
  rdfs:label "FluMist Quadrivalent 2019-2020" .

obo:VO_0019027 a obo:VO_0015077 ;
  rdfs:label "Flumist Quadrivalent 2020-2021" .

obo:VO_0019028 a obo:VO_0015077 ;
  rdfs:label "FluMist Quadrivalent 2021-2022" .

obo:VO_0019029 a obo:VO_0015077 ;
  rdfs:label "FluMist Quadrivalent 2022-2023" .

obo:VO_0019030 a obo:VO_0015077 ;
  rdfs:label "Fluvirin 2010-2011 Formula" .

obo:VO_0019031 a obo:VO_0015077 ;
  rdfs:label "Fluvirin 2011-2012 Formula" .

obo:VO_0019032 a obo:VO_0015077 ;
  rdfs:label "Fluvirin 2012-2013 Formula" .

obo:VO_0019033 a obo:VO_0015077 ;
  rdfs:label "Fluvirin 2013-2014 Formula" .

obo:VO_0019034 a obo:VO_0015077 ;
  rdfs:label "Fluvirin 2014-2015 Formula" .

obo:VO_0019035 a obo:VO_0015077 ;
  rdfs:label "Fluvirin 2015-2016" .

obo:VO_0019036 a obo:VO_0015077 ;
  rdfs:label "Fluvirin 2016-2017" .

obo:VO_0019037 a obo:VO_0015077 ;
  rdfs:label "Fluvirin 2017-2018" .

obo:VO_0019038 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2010-2011 Formula" .

obo:VO_0019039 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2011-2012 Formula" .

obo:VO_0019040 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2012-2013 Formula" .

obo:VO_0019041 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2013-2014 Formula" .

obo:VO_0019042 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2014-2015 Formula" .

obo:VO_0019043 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2015-2016" .

obo:VO_0019044 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2016-2017" .

obo:VO_0019045 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2017-2018" .

obo:VO_0019046 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2018-2019" .

obo:VO_0019047 a obo:VO_0015077 ;
  rdfs:label "Fluzone 2019-2020" .

obo:VO_0019048 a obo:VO_0015077 ;
  rdfs:label "Fluzone High-Dose 2012-2013 Formula" .

obo:VO_0019049 a obo:VO_0015077 ;
  rdfs:label "Fluzone High-Dose 2013-2014 Formula" .

obo:VO_0019050 a obo:VO_0015077 ;
  rdfs:label "Fluzone High-Dose 2014-2015 Formula" .

obo:VO_0019051 a obo:VO_0015077 ;
  rdfs:label "Fluzone Intradermal 2012-2013 Formula" .

obo:VO_0019052 a obo:VO_0015077 ;
  rdfs:label "Fluzone Intradermal 2013-2014 Formula" .

obo:VO_0019053 a obo:VO_0015077 ;
  rdfs:label "Fluzone Intradermal 2014-2015 Formula" .

obo:VO_0019054 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2013-2014 Formula" .

obo:VO_0019055 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2014-2015 Formula" .

obo:VO_0019056 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2015-2016" .

obo:VO_0019057 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2016 Southern Hemisphere" .

obo:VO_0019058 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2016-2017" .

obo:VO_0019059 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2017-2018" .

obo:VO_0019060 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2018-2019" .

obo:VO_0019061 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2019-2020" .

obo:VO_0019062 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2020 Southern Hemisphere" .

obo:VO_0019063 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2020-2021" .

obo:VO_0019064 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2021 Southern Hemisphere" .

obo:VO_0019065 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2021-2022" .

obo:VO_0019066 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2022 Southern Hemisphere" .

obo:VO_0019067 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2022-2023" .

obo:VO_0019068 a obo:VO_0015077 ;
  rdfs:label "Fluzone Quadrivalent 2023 Southern Hemisphere" .

obo:VO_0019069 a obo:VO_0015077 ;
  rdfs:label "Gardasil 9" .

obo:VO_0019070 a obo:VO_0015077 ;
  rdfs:label "HB-VAX" .

obo:VO_0019071 a obo:VO_0015077 ;
  rdfs:label "Heplisav-B" .

obo:VO_0019072 a obo:VO_0015077 ;
  rdfs:label "Kinrix" .

obo:VO_0019073 a obo:VO_0015077 ;
  rdfs:label "Liquid PedvaxHIB" .

obo:VO_0019074 a obo:VO_0015077 ;
  rdfs:label "MenHibrix" .

obo:VO_0019075 a obo:VO_0015077 ;
  rdfs:label "Meningovax-AC" .

obo:VO_0019076 a obo:VO_0015077 ;
  rdfs:label "Menomune A/C/Y/W-135" .

obo:VO_0019077 a obo:VO_0015077 ;
  rdfs:label "Meruvax II" .

obo:VO_0019078 a obo:VO_0015077 ;
  rdfs:label "OmniHIB" .

obo:VO_0019079 a obo:VO_0015077 ;
  rdfs:label "Pediarix" .

obo:VO_0019080 a obo:VO_0015077 ;
  rdfs:label "Pentacel" .

obo:VO_0019081 a obo:VO_0015077 ;
  rdfs:label "Prehevbrio" .

obo:VO_0019082 a obo:VO_0015077 ;
  rdfs:label "Prevnar 13" .

obo:VO_0019083 a obo:VO_0015077 ;
  rdfs:label "Prohibit" .

obo:VO_0019084 a obo:VO_0015077 ;
  rdfs:label "RotaTeq" .

obo:VO_0019085 a obo:VO_0015077 ;
  rdfs:label "Shingrix" .

obo:VO_0019086 a obo:VO_0015077 ;
  rdfs:label "Spikevax" .

obo:VO_0019087 a obo:VO_0015077 ;
  rdfs:label "Tdvax" .

obo:VO_0019088 a obo:VO_0015077 ;
  rdfs:label "TE Anatoxal Berna" .

obo:VO_0019089 a obo:VO_0015077 ;
  rdfs:label "Tenivac" .

obo:VO_0019090 a obo:VO_0015077 ;
  rdfs:label "Tripedia" .

obo:VO_0019091 a obo:VO_0015077 ;
  rdfs:label "Varivax" .

obo:VO_0019092 a obo:VO_0015077 ;
  rdfs:label "Vaxchora" .

obo:VO_0019093 a obo:VO_0015077 ;
  rdfs:label "Vaxelis" .

obo:VO_0019094 a obo:VO_0015077 ;
  rdfs:label "Vivotif" .

obo:VO_0019095 a obo:VO_0015077 ;
  rdfs:label "YF-Vax" .

obo:VO_0019096 a obo:VO_0015077 ;
  rdfs:label "Zostavax" .

obo:VO_0019418 a obo:VO_0015077 ;
  rdfs:label "Liquid Pedvax HIB" .

obo:VO_0020356 a obo:VO_0015077 ;
  rdfs:label "Typhim V" .

obo:VO_0020357 a obo:VO_0015077 ;
  rdfs:label "Typhoral L" .

obo:VO_0020650 a obo:VO_0015077 ;
  rdfs:label "Afluria" .

obo:VO_0020653 a obo:VO_0015077 ;
  rdfs:label "Agrippal" .

obo:VO_0021049 a obo:VO_0015077 ;
  rdfs:label "Alpha RIX Tetra" .

obo:VO_0021050 a obo:VO_0015077 ;
  rdfs:label "Bcg Medac" .

obo:VO_0021051 a obo:VO_0015077 ;
  rdfs:label "Begripal" .

obo:VO_0021052 a obo:VO_0015077 ;
  rdfs:label "Fluad" .

obo:VO_0021053 a obo:VO_0015077 ;
  rdfs:label "Fluarix" .

obo:VO_0021054 a obo:VO_0015077 ;
  rdfs:label "Fluenz" .

obo:VO_0021055 a obo:VO_0015077 ;
  rdfs:label "Flumist" .

obo:VO_0021056 a obo:VO_0015077 ;
  rdfs:label "FluMist Quadrivalent" .

obo:VO_0021057 a obo:VO_0015077 ;
  rdfs:label "Fluvax" .

obo:VO_0021058 a obo:VO_0015077 ;
  rdfs:label "Grippe-Impfstoff Csl" .

obo:VO_0021059 a obo:VO_0015077 ;
  rdfs:label "Grippe-Impfstoff Stada" .

obo:VO_0021060 a obo:VO_0015077 ;
  rdfs:label "Grippeimpfstoff Ratiopharm" .

obo:VO_0021061 a obo:VO_0015077 ;
  rdfs:label "ImmuCyst" .

obo:VO_0021062 a obo:VO_0015077 ;
  rdfs:label "IMMUGRIP" .

obo:VO_0021063 a obo:VO_0015077 ;
  rdfs:label "Inflexal" .

obo:VO_0021064 a obo:VO_0015077 ;
  rdfs:label "Influsplit" .

obo:VO_0021065 a obo:VO_0015077 ;
  rdfs:label "INFLUVAC" .

obo:VO_0021066 a obo:VO_0015077 ;
  rdfs:label "Intanza" .

obo:VO_0021067 a obo:VO_0015077 ;
  rdfs:label "InterVax" .

obo:VO_0021068 a obo:VO_0015077 ;
  rdfs:label "Metavirulent" .

obo:VO_0021069 a obo:VO_0015077 ;
  rdfs:label "OncoTICE" .

obo:VO_0021070 a obo:VO_0015077 ;
  rdfs:label "Oncotice Bcg" .

obo:VO_0021071 a obo:VO_0015077 ;
  rdfs:label "Pacis" .

obo:VO_0021072 a obo:VO_0015077 ;
  rdfs:label "Pandemrix" .

obo:VO_0021073 a obo:VO_0015077 ;
  rdfs:label "Preflucel" .

obo:VO_0021074 a obo:VO_0015077 ;
  rdfs:label "Varilrix" .

obo:VO_0021075 a obo:VO_0015077 ;
  rdfs:label "VAXIGRIP" .

obo:VO_0021076 a obo:VO_0015077 ;
  rdfs:label "Vaxigrip Junior" .

obo:VO_0021077 a obo:VO_0015077 ;
  rdfs:label "Viroflu" .

obo:VO_0021078 a obo:VO_0015077 ;
  rdfs:label "Xanaflu" .

obo:VO_0015076 a rdfs:Class ;
  rdfs:label "drug package" ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VO_0015078 a obo:VO_0015076 ;
  rdfs:label "Box of 1" .

obo:VO_0015079 a obo:VO_0015076 ;
  rdfs:label "Box of 10" .

obo:VO_0015082 a obo:VO_0015076 ;
  rdfs:label "Box of 20" .

obo:VO_0015083 a obo:VO_0015076 ;
  rdfs:label "Box of 50" .

obo:VO_0015349 a obo:VO_0015076 ;
  rdfs:label "Box of 2" .

obo:VO_0015350 a obo:VO_0015076 ;
  rdfs:label "Box of 3" .

obo:VO_0015351 a obo:VO_0015076 ;
  rdfs:label "Box of 5" .

obo:VO_0015352 a obo:VO_0015076 ;
  rdfs:label "Box of 25" .

obo:VO_0015353 a obo:VO_0015076 ;
  rdfs:label "Box of 40" .

obo:VO_0015354 a obo:VO_0015076 ;
  rdfs:label "Box of 80" .

obo:VO_0015355 a obo:VO_0015076 ;
  rdfs:label "Box of 100" .

obo:VO_0015356 a obo:VO_0015076 ;
  rdfs:label "Box of 250" .

obo:VO_0021079 a obo:VO_0015076 ;
  rdfs:label "Box of 6" .

obo:VO_0010395 a rdfs:Class ;
  rdfs:label "flu season" ;
  rdfs:comment "A period typically associated with a higher incidence of influenza virus infections, characterized by the increased circulation of flu viruses in a population." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:VO_0010397 a obo:VO_0010395 ;
  rdfs:label "flu season 2013-2014" .

obo:VO_0010398 a obo:VO_0010395 ;
  rdfs:label "flu season 2014-2015" .

obo:VO_0010399 a obo:VO_0010395 ;
  rdfs:label "flu season 2012-2013" .

obo:VO_0010400 a obo:VO_0010395 ;
  rdfs:label "flu season 2011-2012" .

obo:VO_0010401 a obo:VO_0010395 ;
  rdfs:label "flu season 2019-2020" .

obo:VO_0010402 a obo:VO_0010395 ;
  rdfs:label "flu season 2020" .

obo:VO_0010403 a obo:VO_0010395 ;
  rdfs:label "flu season 2016" .

obo:VO_0010404 a obo:VO_0010395 ;
  rdfs:label "flu season 2021-2022" .

obo:VO_0010405 a obo:VO_0010395 ;
  rdfs:label "flu season 2020-2021" .

obo:VO_0010406 a obo:VO_0010395 ;
  rdfs:label "flu season 2021" .

obo:VO_0010407 a obo:VO_0010395 ;
  rdfs:label "flu season 2010-2011" .

obo:VO_0010408 a obo:VO_0010395 ;
  rdfs:label "flu season 2015-2016" .

obo:VO_0010409 a obo:VO_0010395 ;
  rdfs:label "flu season 2022-2023" .

obo:VO_0010410 a obo:VO_0010395 ;
  rdfs:label "flu season 2023" .

obo:VO_0010411 a obo:VO_0010395 ;
  rdfs:label "flu season 2022" .

obo:VO_0010412 a obo:VO_0010395 ;
  rdfs:label "flu season 2018-2019" .

obo:VO_0010413 a obo:VO_0010395 ;
  rdfs:label "flu season 2016-2017" .

obo:VO_0010414 a obo:VO_0010395 ;
  rdfs:label "flu season 2017-2018" .

obo:VO_0000299 a rdfs:Class ;
  rdfs:label "company" ;
  rdfs:comment "A legal organization that represents an association of people with a specific objective." ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:VO_0000023 a obo:VO_0000299 ;
  rdfs:label "Invitrogen" .

obo:VO_0000056 a obo:VO_0000299 ;
  rdfs:label "United Vaccines, Inc" .

obo:VO_0000057 a obo:VO_0000299 ;
  rdfs:label "Heska Corporation" .

obo:VO_0000058 a obo:VO_0000299 ;
  rdfs:label "Texas Vet lab, Inc" .

obo:VO_0000059 a obo:VO_0000299 ;
  rdfs:label "SolidTech Animal Health, Inc" .

obo:VO_0000060 a obo:VO_0000299 ;
  rdfs:label "MVP Laboratories, Inc" .

obo:VO_0000061 a obo:VO_0000299 ;
  rdfs:label "Addison Biological Laboratory, Inc" .

obo:VO_0000062 a obo:VO_0000299 ;
  rdfs:label "Neotech, LLC" .

obo:VO_0000149 a obo:VO_0000299 ;
  rdfs:label "Aceto Pharma Corp" .

obo:VO_0000204 a obo:VO_0000299 ;
  rdfs:label "Intervet" .

obo:VO_0000205 a obo:VO_0000299 ;
  rdfs:label "Fort Dodge" .

obo:VO_0000264 a obo:VO_0000299 ;
  rdfs:label "ProtaTek International, Inc" .

obo:VO_0000265 a obo:VO_0000299 ;
  rdfs:label "Arko Laboratories Ltd" .

obo:VO_0000268 a obo:VO_0000299 ;
  rdfs:label "Newport Laboratories, Inc" .

obo:VO_0000269 a obo:VO_0000299 ;
  rdfs:label "Texas Agricultural Experiment Station" .

obo:VO_0000296 a obo:VO_0000299 ;
  rdfs:label "Brinton Laboratories Inc" .

obo:VO_0000570 a obo:VO_0000299 ;
  rdfs:label "Novartis Animal Health US, Inc." .

obo:VO_0000607 a obo:VO_0000299 ;
  rdfs:label "Intercell Biomedical" .

obo:VO_0000686 a obo:VO_0000299 ;
  rdfs:label "Acambis, Inc" .

obo:VO_0000687 a obo:VO_0000299 ;
  rdfs:label "Berna Biotech, Ltd" .

obo:VO_0000688 a obo:VO_0000299 ;
  rdfs:label "BioPort Corp" .

obo:VO_0000689 a obo:VO_0000299 ;
  rdfs:label "CSL Limited" .

obo:VO_0000690 a obo:VO_0000299 ;
  rdfs:label "GlaxoSmithKline plc" ;
  rdfs:comment "A British multinational pharmaceutical company headquartered in Brentford, England" .

obo:VO_0000691 a obo:VO_0000299 ;
  rdfs:label "Greer Laboratories Inc" .

obo:VO_0000693 a obo:VO_0000299 ;
  rdfs:label "Massachusetts Public Health Biologic Lab" .

obo:VO_0000694 a obo:VO_0000299 ;
  rdfs:label "MedImmune Vaccines, Inc" .

obo:VO_0000695 a obo:VO_0000299 ;
  rdfs:label "Merck & Co., Inc." .

obo:VO_0000696 a obo:VO_0000299 ;
  rdfs:label "Novartis Vaccines and Diagnostics" .

obo:VO_0000697 a obo:VO_0000299 ;
  rdfs:label "Organon Teknika Corp LLC" .

obo:VO_0000698 a obo:VO_0000299 ;
  rdfs:label "Research Foundation for Microbial Diseases of Osaka University" .

obo:VO_0000699 a obo:VO_0000299 ;
  rdfs:label "Sanofi Pasteur Limited" .

obo:VO_0000700 a obo:VO_0000299 ;
  rdfs:label "Sanofi Pasteur, Inc" .

obo:VO_0000701 a obo:VO_0000299 ;
  rdfs:label "Wyeth Pharmaceuticals Inc" .

obo:VO_0000703 a obo:VO_0000299 ;
  rdfs:label "Sanofi Pasteur, SA" .

obo:VO_0000821 a obo:VO_0000299 ;
  rdfs:label "Vetech Labs" .

obo:VO_0000841 a obo:VO_0000299 ;
  rdfs:label "Pfizer Animal Health" .

obo:VO_0000846 a obo:VO_0000299 ;
  rdfs:label "BIOPHARM" .

obo:VO_0000848 a obo:VO_0000299 ;
  rdfs:label "Cutter Biological" .

obo:VO_0000861 a obo:VO_0000299 ;
  rdfs:label "Bioproperties" .

obo:VO_0000869 a obo:VO_0000299 ;
  rdfs:label "Solvay Pharmaceuticals" .

obo:VO_0000877 a obo:VO_0000299 ;
  rdfs:label "Websters Animal Health" .

obo:VO_0000890 a obo:VO_0000299 ;
  rdfs:label "Colorado Serum Company CZ Veterinaria" .

obo:VO_0000892 a obo:VO_0000299 ;
  rdfs:label "Biken" .

obo:VO_0000893 a obo:VO_0000299 ;
  rdfs:label "Schering-Plough" .

obo:VO_0000895 a obo:VO_0000299 ;
  rdfs:label "Baxter Healthcare Corporation" .

obo:VO_0000896 a obo:VO_0000299 ;
  rdfs:label "Merck Frosst" .

obo:VO_0000901 a obo:VO_0000299 ;
  rdfs:label "Boehringer-Ingelheim Vetmedica, Inc" .

obo:VO_0000904 a obo:VO_0000299 ;
  rdfs:label "SBL Vaccine" .

obo:VO_0000905 a obo:VO_0000299 ;
  rdfs:label "Wyeth Canada" .

obo:VO_0000914 a obo:VO_0000299 ;
  rdfs:label "Virbac" .

obo:VO_0000959 a obo:VO_0000299 ;
  rdfs:label "Embrex" .

obo:VO_0000964 a obo:VO_0000299 ;
  rdfs:label "Novartis Animal Health" .

obo:VO_0000971 a obo:VO_0000299 ;
  rdfs:label "Novartis" .

obo:VO_0000989 a obo:VO_0000299 ;
  rdfs:label "Novus International" .

obo:VO_0001001 a obo:VO_0000299 ;
  rdfs:label "Biomune" .

obo:VO_0001006 a obo:VO_0000299 ;
  rdfs:label "Vical, Inc." .

obo:VO_0001010 a obo:VO_0000299 ;
  rdfs:label "Promega" .

obo:VO_0001027 a obo:VO_0000299 ;
  rdfs:label "Lohman Animal Health International" .

obo:VO_0001058 a obo:VO_0000299 ;
  rdfs:label "Centre for Ticks and Tickborne Disease, Malawi" .

obo:VO_0001069 a obo:VO_0000299 ;
  rdfs:label "ImmunoVaccine Technologies, Canada" .

obo:VO_0001079 a obo:VO_0000299 ;
  rdfs:label "Local veterinary institutes" .

obo:VO_0001119 a obo:VO_0000299 ;
  rdfs:label "Merial, Inc" .

obo:VO_0001174 a obo:VO_0000299 ;
  rdfs:label "Schering-Plough Animal Health" .

obo:VO_0001179 a obo:VO_0000299 ;
  rdfs:label "Bayer Leverkusen" .

obo:VO_0001212 a obo:VO_0000299 ;
  rdfs:label "Coopers Animal Health" .

obo:VO_0001219 a obo:VO_0000299 ;
  rdfs:label "Dow AgroSciences" .

obo:VO_0001458 a obo:VO_0000299 ;
  rdfs:label "International Duck Research Cooperative, Inc." .

obo:VO_0001529 a obo:VO_0000299 ;
  rdfs:label "VacciCel, Inc." ;
  rdfs:comment """Vaccicel, Inc. has a location in Belton, TX. Active officers include Andre Menchu, Andres Menchu, Kathryn M Baker, Katheryn Becker and Andres Menches. Vaccicel, Inc. filed as a Domestic For-Profit Corporation on Tuesday, August 22, 1995 in the state of Texas and is currently active. Andres Menchu serves as the registered agent for this organization.The company's line of business includes Mfg Research & Development Veterinary Bacterial Vaccines. 
(http://www.corporationwiki.com/Texas/Belton/vaccicel-inc/34296230.aspx)""" .

obo:VO_0002498 a obo:VO_0000299 ;
  rdfs:label "ID Biomedical Corporation of Quebec" ;
  rdfs:comment """GSK Acquires Influenza Vaccine Manufacturer ID Biomedical Corporation
http://www.medicalnewstoday.com/releases/34803.php

GlaxoSmithKline plc (NYSE:GSK) announced the completion of the acquisition of ID Biomedical. This follows regulatory clearances of the transaction and adoption of the acquisition agreement by ID Biomedical's shareholders (which occurred on the 16th of November). ID Biomedical becomes a wholly-owned subsidiary of GSK. ...""" .

obo:VO_0003069 a obo:VO_0000299 ;
  rdfs:label "Protein Sciences Corporation" .

obo:VO_0003076 a obo:VO_0000299 ;
  rdfs:label "Valneva SE" .

obo:VO_0003078 a obo:VO_0000299 ;
  rdfs:label "Israel Institute for Biological Research" ;
  rdfs:comment "An Israeli research and development laboratory" .

obo:VO_0003079 a obo:VO_0000299 ;
  rdfs:label "PaxVax, Inc." .

obo:VO_0003089 a obo:VO_0000299 ;
  rdfs:label "Lederle Laboratories Division" ;
  rdfs:comment "Out of buisness" .

obo:VO_0003123 a obo:VO_0000299 ;
  rdfs:label "Abbot Laboratories" .

obo:VO_0003125 a obo:VO_0000299 ;
  rdfs:label "Parke, Davis, Company" .

obo:VO_0003132 a obo:VO_0000299 ;
  rdfs:label "Max Planck Institute for Infection Biology" .

obo:VO_0003137 a obo:VO_0000299 ;
  rdfs:label "Bio-Manguinhos" .

obo:VO_0003145 a obo:VO_0000299 ;
  rdfs:label "Mylan Products Limited" .

obo:VO_0003149 a obo:VO_0000299 ;
  rdfs:label "French National Agency for Research on AIDS and Viral Hepatitis (ANRS)" .

obo:VO_0003153 a obo:VO_0000299 ;
  rdfs:label "Dynavax Technologies Corporation" ;
  rdfs:comment "A company trhat is located at Berkeley, CA, USA. Its website is: http://www.dynavax.com." .

obo:VO_0003157 a obo:VO_0000299 ;
  rdfs:label "Novavax, Inc." ;
  rdfs:comment "Novavax, Inc. is a clinical-stage biotechnology company committed to delivering novel products to prevent a broad range of infectious diseases." .

obo:VO_0003163 a obo:VO_0000299 ;
  rdfs:label "Teva Pharmaceuticals USA, Inc." .

obo:VO_0003164 a obo:VO_0000299 ;
  rdfs:label "Seqirus, Inc." .

obo:VO_0003166 a obo:VO_0000299 ;
  rdfs:label "Connaught Laboratories, Inc." ;
  rdfs:comment "Located in Swiftwater, Pennsylvania, this company is now known as Sanofi Pasteur Limited." .

obo:VO_0003179 a obo:VO_0000299 ;
  rdfs:label "Chiron Behring Vaccines Private Ltd" .

obo:VO_0004892 a obo:VO_0000299 ;
  rdfs:label "Advent Srl., Italy" ;
  rdfs:comment """ADVENT SRL
VIA CRESCENZIO 9
ROMA, ROMA, 00193  Italy
+39-0691093692
Company Type: Corporation Subsidiary
http://www.hoovers.com/company-information/cs/company-profile.advent_srl.aebb99e74ae57b09.html?aka_re=1""" .

obo:VO_0004932 a obo:VO_0000299 ;
  rdfs:label "Janssen Pharmaceutica" ;
  rdfs:comment "A pharmaceutical company that was founded in 1953 by Paul Janssen, is headquartered in Beerse, Belgium, and owned by Johnson & Johnson." .

obo:VO_0004945 a obo:VO_0000299 ;
  rdfs:label "CanSino Biologics" .

obo:VO_0004946 a obo:VO_0000299 ;
  rdfs:label "BioNTech" ;
  rdfs:comment "A German biotechnology company that is dedicated to the development and manufacture of active immunotherapies for a patient-specific approach to the treatment of serious diseases." .

obo:VO_0004947 a obo:VO_0000299 ;
  rdfs:label "Pfizer Inc." ;
  rdfs:comment "An American multinational pharmaceutical corporation headquartered in New York City." .

obo:VO_0004948 a obo:VO_0000299 ;
  rdfs:label "AstraZeneca" ;
  rdfs:comment "A British-Swedish multinational pharmaceutical and biopharmaceutical company with its headquarters in Cambridge, United Kingdom and Sodertalje, Sweden. AstraZeneca makes products for major disease areas including cancer, cardiovascular, gastrointestinal, infection, neuroscience, respiratory and inflammation." .

obo:VO_0004949 a obo:VO_0000299 ;
  rdfs:label "Beijing Institute of Biological Products" .

obo:VO_0004950 a obo:VO_0000299 ;
  rdfs:label "Sinopharm Group Co., Ltd." .

obo:VO_0004951 a obo:VO_0000299 ;
  rdfs:label "Wuhan Institute of Biological Products" .

obo:VO_0004952 a obo:VO_0000299 ;
  rdfs:label "Gamaleya Research Institute" .

obo:VO_0004953 a obo:VO_0000299 ;
  rdfs:label "Moderna" .

obo:VO_0004954 a obo:VO_0000299 ;
  rdfs:label "Sinovac Biotech Ltd" ;
  rdfs:comment "A biopharmaceutical company headquartered in Beijing, China" .

obo:VO_0004955 a obo:VO_0000299 ;
  rdfs:label "AnGes, Inc." .

obo:VO_0004956 a obo:VO_0000299 ;
  rdfs:label "Arcturus Therapeutics" ;
  rdfs:comment "An American biotech company focused on the discovery, development and commercialization of therapeutics for rare diseases with focus on RNA" .

obo:VO_0004957 a obo:VO_0000299 ;
  rdfs:label "Beijing Minhai Biotechnology Co., Ltd." .

obo:VO_0004958 a obo:VO_0000299 ;
  rdfs:label "Vaxxinity" .

obo:VO_0004959 a obo:VO_0000299 ;
  rdfs:label "Beijing Wantai Biological Pharmacy" .

obo:VO_0004960 a obo:VO_0000299 ;
  rdfs:label "State Research Center of Virology and Biotechnology VECTOR" .

obo:VO_0004961 a obo:VO_0000299 ;
  rdfs:label "Genexine, Inc." .

obo:VO_0004962 a obo:VO_0000299 ;
  rdfs:label "Inovio Pharmaceuticals, Inc." ;
  rdfs:comment "An American biotechnology company focused on the discovery, development, and commercialization of synthetic DNA products for treating cancers and infectious diseases" .

obo:VO_0004963 a obo:VO_0000299 ;
  rdfs:label "Kentucky Bioprocessing, Inc." .

obo:VO_0004964 a obo:VO_0000299 ;
  rdfs:label "Anhui Zhifei Longcom Biopharmaceutical Co., Ltd." .

obo:VO_0004965 a obo:VO_0000299 ;
  rdfs:label "Serum Institute of India" ;
  rdfs:comment "A manufacturer of immunobiological drugs including vaccines in India" .

obo:VO_0004966 a obo:VO_0000299 ;
  rdfs:label "Zydus Cadila" .

obo:VO_0004967 a obo:VO_0000299 ;
  rdfs:label "Adimmune Corporation" .

obo:VO_0004968 a obo:VO_0000299 ;
  rdfs:label "Walvax Biotechnology Co., Ltd." ;
  rdfs:comment "A China-based company principally engaged in the research, development, production and distribution of vaccines, monoclonal antibodies and blood products" .

obo:VO_0004969 a obo:VO_0000299 ;
  rdfs:label "Symvivo" .

obo:VO_0004970 a obo:VO_0000299 ;
  rdfs:label "Chulalongkorn University" .

obo:VO_0004971 a obo:VO_0000299 ;
  rdfs:label "Imperial College London" ;
  rdfs:comment "A public research university in London" .

obo:VO_0004972 a obo:VO_0000299 ;
  rdfs:label "Medicago Inc." ;
  rdfs:comment "A Canadian biotechnology company focused on the discovery, development, and commercialization of virus-like particles using plants as \"bioreactors\" to produce proteins as candidate vaccines and medications" .

obo:VO_0004973 a obo:VO_0000299 ;
  rdfs:label "Entos Pharmaceuticals" .

obo:VO_0004974 a obo:VO_0000299 ;
  rdfs:label "ReiThera Srl" .

obo:VO_0004975 a obo:VO_0000299 ;
  rdfs:label "ImmunityBio, Inc." .

obo:VO_0004976 a obo:VO_0000299 ;
  rdfs:label "NantKwest, Inc." .

obo:VO_0004977 a obo:VO_0000299 ;
  rdfs:label "University Medical Center Hamburg-Eppendorf" ;
  rdfs:comment "The teaching hospital of the University of Hamburg and one of the largest hospitals in Hamburg, Germany" .

obo:VO_0004978 a obo:VO_0000299 ;
  rdfs:label "Medigen, Inc." .

obo:VO_0004979 a obo:VO_0000299 ;
  rdfs:label "Sichuan University" ;
  rdfs:comment "A public research university in Chengdu, Sichuan, China" .

obo:VO_0004980 a obo:VO_0000299 ;
  rdfs:label "Vaxine Pty Ltd." .

obo:VO_0004981 a obo:VO_0000299 ;
  rdfs:label "Instituto Finlay de Vacunas" .

obo:VO_0004982 a obo:VO_0000299 ;
  rdfs:label "Clover Biopharmaceuticals, Inc." .

obo:VO_0004983 a obo:VO_0000299 ;
  rdfs:label "Institut Pasteur" ;
  rdfs:comment "A French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines" .

obo:VO_0004984 a obo:VO_0000299 ;
  rdfs:label "COVAXX" .

obo:VO_0004985 a obo:VO_0000299 ;
  rdfs:label "University of Queensland" ;
  rdfs:comment "A public research university located primarily in Brisbane, Queensland, Australia" .

obo:VO_0004986 a obo:VO_0000299 ;
  rdfs:label "Vaxart, Inc." ;
  rdfs:comment "An American biotechnology company focused on the discovery, development, and commercialization of oral recombinant vaccines" .

obo:VO_0004997 a obo:VO_0000299 ;
  rdfs:label "Cellid Co., Ltd." .

obo:VO_0004998 a obo:VO_0000299 ;
  rdfs:label "University Medical Center Groningen" .

obo:VO_0005080 a obo:VO_0000299 ;
  rdfs:label "AIVITA Biomedical, Inc." .

obo:VO_0005086 a obo:VO_0000299 ;
  rdfs:label "Sanofi S.A." ;
  rdfs:comment "Sanofi S.A. is a French multinational pharmaceutical company headquartered in Paris, France." .

obo:VO_0005208 a obo:VO_0000299 ;
  rdfs:label "CureVac AG" .

obo:VO_0005209 a obo:VO_0000299 ;
  rdfs:label "Research Institute for Biological Safety Problems" .

obo:VO_0005210 a obo:VO_0000299 ;
  rdfs:label "Bharat Biotech International Limited" .

obo:VO_0005211 a obo:VO_0000299 ;
  rdfs:label "University of Munich (Ludwig-Maximilians)" .

obo:VO_0005212 a obo:VO_0000299 ;
  rdfs:label "West China Hospital" .

obo:VO_0005213 a obo:VO_0000299 ;
  rdfs:label "University Hospital Tuebingen" .

obo:VO_0005214 a obo:VO_0000299 ;
  rdfs:label "Shenzhen Geno-Immune Medical Institute" .

obo:VO_0005215 a obo:VO_0000299 ;
  rdfs:label "Providence Health & Services" .

obo:VO_0005216 a obo:VO_0000299 ;
  rdfs:label "City of Hope Medical Center" .

obo:VO_0005217 a obo:VO_0000299 ;
  rdfs:label "Codagenix, Inc." .

obo:VO_0005218 a obo:VO_0000299 ;
  rdfs:label "Center for Genetic Engineering and Biotechnology" .

obo:VO_0005219 a obo:VO_0000299 ;
  rdfs:label "Biological E. Ltd" .

obo:VO_0005220 a obo:VO_0000299 ;
  rdfs:label "GeneOne Life Science, Inc." .

obo:VO_0005221 a obo:VO_0000299 ;
  rdfs:label "Nanogen Pharmaceutical Biotechnology" .

obo:VO_0005222 a obo:VO_0000299 ;
  rdfs:label "Shionogi" .

obo:VO_0005223 a obo:VO_0000299 ;
  rdfs:label "Altimmune, Inc." .

obo:VO_0005224 a obo:VO_0000299 ;
  rdfs:label "Erciyes University" .

obo:VO_0005225 a obo:VO_0000299 ;
  rdfs:label "Vaccine and Infectious Disease Organization" .

obo:VO_0005564 a obo:VO_0000299 ;
  rdfs:label "Barr Laboratories, Inc." .

obo:VO_0005565 a obo:VO_0000299 ;
  rdfs:label "Daiichi Sankyo Co., Ltd." .

obo:VO_0005566 a obo:VO_0000299 ;
  rdfs:label "Elixirgen Therapeutics, Inc." ;
  rdfs:comment "A company advancing its controllable self-replicating RNA technology to develop therapies for a broad spectrum of diseases, including rare diseases, aging-related disorders, and cancer." .

obo:VO_0005567 a obo:VO_0000299 ;
  rdfs:label "Emergent BioDefense Operations Lansing LLC" ;
  rdfs:comment "A company offers pharmaceutical and specialized products to healthcare providers located in United States." .

obo:VO_0005568 a obo:VO_0000299 ;
  rdfs:label "Emergent Product Development Gaithersburg, Inc." ;
  rdfs:comment "A company located in Gaithersburg, Maryland." .

obo:VO_0005569 a obo:VO_0000299 ;
  rdfs:label "Sanaria Inc., Rockville, MD" ;
  rdfs:comment "A company dedicated to the production of a vaccine protective against malaria caused by the pathogen Plasmodium falciparum." .

obo:VO_0005570 a obo:VO_0000299 ;
  rdfs:label "Seqirus Pty. Ltd" .

obo:VO_0005571 a obo:VO_0000299 ;
  rdfs:label "Seqirus Vaccines Limited" .

obo:VO_0005572 a obo:VO_0000299 ;
  rdfs:label "Syneos Health" .

obo:VO_0010377 a obo:VO_0000299 ;
  rdfs:label "Organon Teknika Corp., LLC" .

obo:VO_0010379 a obo:VO_0000299 ;
  rdfs:label "Merck Sharp & Dohme LLC" .

obo:VO_0010380 a obo:VO_0000299 ;
  rdfs:label "Emergent Product Development Gaithersburg Inc." .

obo:VO_0010381 a obo:VO_0000299 ;
  rdfs:label "Valneva Austria GmbH" .

obo:VO_0010382 a obo:VO_0000299 ;
  rdfs:label "Bavarian Nordic" .

obo:VO_0010383 a obo:VO_0000299 ;
  rdfs:label "ModernaTX, Inc." .

obo:VO_0010384 a obo:VO_0000299 ;
  rdfs:label "Pfizer Ireland Pharmaceuticals" .

obo:VO_0010385 a obo:VO_0000299 ;
  rdfs:label "VBI Vaccines (Delaware) Inc." .

obo:VO_0010386 a obo:VO_0000299 ;
  rdfs:label "Moderna Tx Inc." .

obo:VO_0010387 a obo:VO_0000299 ;
  rdfs:label "MassBiologics" .

obo:VO_0010388 a obo:VO_0000299 ;
  rdfs:label "MSP Vaccine Company" .

obo:VO_0010392 a obo:VO_0000299 ;
  rdfs:label "BioNTech Manufacturing GmbH" .

obo:VO_0007655 a rdfs:Class ;
  rdfs:label "tumor antigen" ;
  rdfs:comment "Either a tumor-specific or a tumor-associated antigen." ;
  rdfs:subClassOf obo:OBI_1110034 .

obo:VO_0010332 a obo:VO_0007655 ;
  rdfs:label "tumor-specific antigen" ;
  rdfs:comment "Antigen that is only expressed by tumor cells." .

obo:VO_0010333 a obo:VO_0007655 ;
  rdfs:label "tumor-associated antigen" ;
  rdfs:comment "Antigen that is overexpressed by tumor cells." .

obo:IAO_0000225 a rdfs:Class ;
  rdfs:label "obsolescence reason specification"@en ;
  rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000103 a obo:IAO_0000225 ;
  rdfs:label "failed exploratory term"@en ;
  rdfs:comment "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en .

obo:IAO_0000226 a obo:IAO_0000225 ;
  rdfs:label "placeholder removed"@en .

obo:IAO_0000227 a obo:IAO_0000225 ;
  rdfs:label "terms merged"@en .

obo:IAO_0000228 a obo:IAO_0000225 ;
  rdfs:label "term imported"@en .

obo:IAO_0000229 a obo:IAO_0000225 ;
  rdfs:label "term split"@en .

obo:OMO_0001000 a obo:IAO_0000225 ;
  rdfs:label "out of scope" ;
  rdfs:comment "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en .

obo:IAO_0000078 a rdfs:Class ;
  rdfs:label "curation status specification"@en ;
  rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000002 a obo:IAO_0000078 ;
  rdfs:label "example to be eventually removed"@en .

obo:IAO_0000120 a obo:IAO_0000078 ;
  rdfs:label "metadata complete"@en ;
  rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en .

obo:IAO_0000121 a obo:IAO_0000078 ;
  rdfs:label "organizational term"@en ;
  rdfs:comment "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en .

obo:IAO_0000122 a obo:IAO_0000078 ;
  rdfs:label "ready for release"@en ;
  rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en .

obo:IAO_0000123 a obo:IAO_0000078 ;
  rdfs:label "metadata incomplete"@en ;
  rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en .

obo:IAO_0000124 a obo:IAO_0000078 ;
  rdfs:label "uncurated"@en ;
  rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en .

obo:IAO_0000125 a obo:IAO_0000078 ;
  rdfs:label "pending final vetting"@en ;
  rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en .

obo:IAO_0000423 a obo:IAO_0000078 ;
  rdfs:label "to be replaced with external ontology term"@en ;
  rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en .

obo:IAO_0000428 a obo:IAO_0000078 ;
  rdfs:label "requires discussion"@en ;
  rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .
