PREFIX obo:
PREFIX rdf:
PREFIX rdfs:
PREFIX xsd:
obo:PHIPO_0001287 a rdfs:Class ;
rdfs:label "normal growth on tolnaftate"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to tolnaftate (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0061101 a rdfs:Class ;
rdfs:label "neuroendocrine cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030182 , obo:GO_0060563 .
obo:BFO_0000051 a rdf:Property ;
rdfs:label "has part" ;
rdfs:comment "a core relation that holds between a whole and its part"@en ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:BFO_0000062 a rdf:Property ;
rdfs:label "preceded by"@en ;
rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002086 .
obo:RO_0002315 a rdf:Property ;
rdfs:label "results in acquisition of features of"@en ;
rdfs:comment "The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity" ;
rdfs:domain obo:GO_0008150 ;
rdfs:range obo:UBERON_0000061 ;
rdfs:subPropertyOf obo:RO_0040036 , obo:RO_0002295 .
obo:BFO_0000063 a rdf:Property ;
rdfs:label "precedes"@en ;
rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002222 .
obo:BFO_0000066 a rdf:Property ;
rdfs:label "occurs in" ;
rdfs:comment "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000004 .
obo:RO_0002337 a rdf:Property ;
rdfs:label "related via localization to"@en ;
rdfs:comment "A relationship that holds via some process of localization" ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 .
obo:RO_0002231 a rdf:Property ;
rdfs:label "has start location"@en ;
rdfs:comment "x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y" ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002479 .
obo:RO_0002232 a rdf:Property ;
rdfs:label "has end location"@en ;
rdfs:comment "x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y" ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002479 .
obo:RO_0019000 a rdf:Property ;
rdfs:label "regulates characteristic" ;
rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:PATO_0000001 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002233 a rdf:Property ;
rdfs:label "has input"@en ;
rdfs:comment "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0000057 .
obo:RO_0002211 a rdf:Property ;
rdfs:label "regulates" ;
rdfs:comment "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002411 .
obo:RO_0002018 a rdf:Property ;
rdfs:label "has component process" ;
rdfs:comment "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002180 .
obo:RO_0002479 a rdf:Property ;
rdfs:label "has part that occurs in" ;
rdfs:comment "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000004 .
obo:BFO_0000050 a rdf:Property ;
rdfs:label "part of" ;
rdfs:comment "a core relation that holds between a part and its whole"@en ;
rdfs:range obo:BFO_0000003 , obo:BFO_0000004 , obo:BFO_0000020 , obo:BFO_0000017 , obo:BFO_0000031 , obo:BFO_0000002 , obo:BFO_0000019 ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0002295 a rdf:Property ;
rdfs:label "results in developmental progression of"@en ;
rdfs:comment "p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss)." ;
rdfs:domain obo:GO_0008150 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002324 .
obo:RO_0002501 a rdf:Property ;
rdfs:label "causal relation between processes" ;
rdfs:comment "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:BFO_0000055 a rdf:Property ;
rdfs:label "realizes"@en ;
rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000017 .
obo:RO_0000057 a rdf:Property ;
rdfs:label "has participant"@en ;
rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 .
obo:RO_0002222 a rdf:Property ;
rdfs:label "temporally related to"@en ;
rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 .
obo:RO_0002334 a rdf:Property ;
rdfs:label "regulated by"@en ;
rdfs:comment "inverse of regulates" ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002427 .
obo:RO_0002414 a rdf:Property ;
rdfs:label "transitively provides input for"@en ;
rdfs:comment "transitive form of directly_provides_input_for" ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0004047 .
obo:CHEBI_33673 a rdfs:Class ;
rdfs:label "zinc group molecular entity" ;
rdfs:subClassOf obo:CHEBI_33676 .
obo:RO_0002473 a rdf:Property ;
rdfs:label "composed primarily of" ;
rdfs:comment "x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:BFO_0000051 .
obo:RO_0002220 a rdf:Property ;
rdfs:label "adjacent to"@en ;
rdfs:comment "x adjacent to y if and only if x and y share a boundary." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002163 .
obo:RO_0002570 a rdf:Property ;
rdfs:label "conduit for" ;
rdfs:comment "x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0002506 a rdf:Property ;
rdfs:label "causal relation between entities" ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002202 a rdf:Property ;
rdfs:label "develops from"@en ;
rdfs:comment "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y" ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002258 , obo:RO_0002254 .
obo:RO_0011002 a rdf:Property ;
rdfs:label "regulates activity of" ;
rdfs:comment "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002566 .
obo:RO_0002566 a rdf:Property ;
rdfs:label "causally influences" ;
rdfs:comment "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002506 .
obo:RO_0000087 a rdf:Property ;
rdfs:label "has role"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000023 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0002215 a rdf:Property ;
rdfs:label "capable of"@en ;
rdfs:comment "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002216 .
obo:RO_0003001 a rdf:Property ;
rdfs:label "produced by"@en ;
rdfs:comment "a produced_by b iff some process that occurs_in b has_output a." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 .
obo:RO_0002330 a rdf:Property ;
rdfs:label "genomically related to"@en ;
rdfs:comment "holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts." ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 .
obo:RO_0000085 a rdf:Property ;
rdfs:label "has function"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000034 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0002375 a rdf:Property ;
rdfs:label "in branching relationship with"@en ;
rdfs:comment "A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002323 .
obo:RO_0002450 a rdf:Property ;
rdfs:label "directly positively regulates activity of" ;
rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.""" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002448 .
obo:RO_0002150 a rdf:Property ;
rdfs:label "continuous with"@en ;
rdfs:comment "X continuous_with Y if and only if X and Y share a fiat boundary." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002323 .
obo:RO_0003000 a rdf:Property ;
rdfs:label "produces"@en ;
rdfs:comment "a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 .
obo:RO_0002449 a rdf:Property ;
rdfs:label "directly negatively regulates activity of" ;
rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.""" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002448 .
obo:RO_0002595 a rdf:Property ;
rdfs:label "causal relation between material entity and a process" ;
rdfs:comment "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002176 a rdf:Property ;
rdfs:label "connects"@en ;
rdfs:comment "c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002323 .
obo:RO_0002448 a rdf:Property ;
rdfs:label "directly regulates activity of" ;
rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.
A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.""" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0011002 , obo:RO_0002436 .
obo:RO_0002258 a rdf:Property ;
rdfs:label "developmentally preceded by"@en ;
rdfs:comment "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p" ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002324 .
obo:RO_0000091 a rdf:Property ;
rdfs:label "has disposition"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000016 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0002206 a rdf:Property ;
rdfs:label "expressed in"@en ;
rdfs:comment "x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process" ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:UBERON_0000465 ;
rdfs:subPropertyOf obo:RO_0002330 .
obo:RO_0000056 a rdf:Property ;
rdfs:label "participates in"@en ;
rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000003 .
obo:RO_0002434 a rdf:Property ;
rdfs:label "interacts with" ;
rdfs:comment "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 .
obo:RO_0002002 a rdf:Property ;
rdfs:label "has 2D boundary"@en ;
rdfs:comment "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity"@en ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000141 ;
rdfs:subPropertyOf obo:RO_0002323 .
obo:RO_0002487 a rdf:Property ;
rdfs:label "relation between physical entity and a process or stage" ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000003 .
obo:GO_0110165 a rdfs:Class ;
rdfs:label "cellular anatomical structure" ;
rdfs:comment "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." ;
rdfs:subClassOf obo:GO_0005575 , obo:UBERON_0000061 , obo:UBERON_0000465 .
obo:RO_0002256 a rdf:Property ;
rdfs:label "developmentally induced by"@en ;
rdfs:comment "t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T" ;
rdfs:domain obo:UBERON_0000465 ;
rdfs:range obo:UBERON_0000465 ;
rdfs:subPropertyOf obo:RO_0002258 .
obo:RO_0002497 a rdf:Property ;
rdfs:label "existence ends during or before" ;
rdfs:comment "x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002487 .
obo:RO_0020105 a rdf:Property ;
rdfs:label "is anatomical entity" ;
rdfs:comment "This property only applies to anatomical entities." ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range .
obo:RO_0002567 a rdf:Property ;
rdfs:label "biomechanically related to" ;
rdfs:comment "A relation that holds between elements of a musculoskeletal system or its analogs." ;
rdfs:domain obo:UBERON_0000061 ;
rdfs:range obo:UBERON_0000061 ;
rdfs:subPropertyOf obo:RO_0002328 .
obo:RO_0002551 a rdf:Property ;
rdfs:label "has skeleton" ;
rdfs:comment "A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision." ;
rdfs:domain obo:UBERON_0000061 ;
rdfs:range ;
rdfs:subPropertyOf obo:BFO_0000051 .
obo:RO_0002177 a rdf:Property ;
rdfs:label "attached to part of"@en ;
rdfs:comment "a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b." ;
rdfs:domain obo:UBERON_0000061 ;
rdfs:range obo:UBERON_0000061 ;
rdfs:subPropertyOf obo:RO_0002567 , obo:RO_0002323 .
obo:RO_0002254 a rdf:Property ;
rdfs:label "has developmental contribution from"@en ;
rdfs:comment "x has developmental contribution from y iff x has some part z such that z develops from y"@en ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002258 .
obo:RO_0002104 a rdf:Property ;
rdfs:label "has plasma membrane part"@en ;
rdfs:comment "Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part." ;
rdfs:domain obo:UBERON_0000465 ;
rdfs:range obo:UBERON_0000465 ;
rdfs:subPropertyOf obo:BFO_0000051 .
obo:RO_0002384 a rdf:Property ;
rdfs:label "has developmental potential involving"@en ;
rdfs:comment "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)."@en ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002324 .
obo:RO_0002005 a rdf:Property ;
rdfs:label "innervated by"@en ;
rdfs:comment "relation between an anatomical structure and a neuron projection bundle that has synaptic terminals in the structure." ;
rdfs:domain obo:UBERON_0000061 ;
rdfs:range obo:UBERON_0000122 .
obo:RO_0002226 a rdf:Property ;
rdfs:label "develops in"@en ;
rdfs:comment "x develops_in y if x is located in y whilst x is developing" ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002258 .
obo:RO_0002576 a rdf:Property ;
rdfs:label "skeleton of" ;
rdfs:comment "inverse of has skeleton" ;
rdfs:domain obo:UBERON_0000061 ;
rdfs:range obo:UBERON_0000061 ;
rdfs:subPropertyOf obo:BFO_0000050 .
obo:RO_0002372 a rdf:Property ;
rdfs:label "has muscle origin"@en ;
rdfs:comment "m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to."@en ;
rdfs:domain obo:UBERON_0000061 ;
rdfs:range obo:UBERON_0000061 ;
rdfs:subPropertyOf obo:RO_0002567 , obo:RO_0002371 .
obo:CL_0000525 a rdfs:Class ;
rdfs:label "syncytiotrophoblast cell" ;
rdfs:comment "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy." ;
rdfs:subClassOf obo:CL_0000351 , obo:CL_4052002 .
obo:RO_0002162 a rdf:Property ;
rdfs:label "in taxon" ;
rdfs:comment "x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed." ;
rdfs:range obo:OBI_0100026 , obo:NCBITaxon_33208 ;
rdfs:subPropertyOf obo:RO_0002320 .
obo:RO_0015004 a rdf:Property ;
rdfs:label "has characterizing marker set" ;
rdfs:comment "A relation that applies between a cell type and a set of markers that can be used to uniquely identify that cell type." ;
rdfs:domain obo:CL_0000000 ;
rdfs:range .
obo:RO_0002353 a rdf:Property ;
rdfs:label "output of"@en ;
rdfs:comment "inverse of has output" ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .
obo:RO_0015016 a rdf:Property ;
rdfs:label "has low plasma membrane amount" ;
rdfs:comment "A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface." ;
rdfs:domain obo:CL_0000000 ;
rdfs:range obo:UBERON_0000465 ;
rdfs:subPropertyOf obo:RO_0002104 .
obo:RO_0002207 a rdf:Property ;
rdfs:label "directly develops from"@en ;
rdfs:comment "Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002202 .
obo:RO_0000053 a rdf:Property ;
rdfs:label "has characteristic"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence"@en ;
rdfs:range obo:BFO_0000020 .
obo:RO_0015015 a rdf:Property ;
rdfs:label "has high plasma membrane amount" ;
rdfs:comment "A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface." ;
rdfs:domain obo:CL_0000000 ;
rdfs:range obo:UBERON_0000465 ;
rdfs:subPropertyOf obo:RO_0002104 .
obo:GO_0003416 a rdfs:Class ;
rdfs:label "endochondral bone growth" ;
rdfs:comment "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone." ;
rdfs:subClassOf obo:GO_0048589 , obo:GO_0098868 .
obo:RO_0002343 a rdf:Property ;
rdfs:label "results in growth of"@en ;
rdfs:domain obo:GO_0008150 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0040036 , obo:RO_0002295 .
obo:GO_0010716 a rdfs:Class ;
rdfs:label "negative regulation of extracellular matrix disassembly" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." ;
rdfs:subClassOf obo:GO_0010715 , obo:GO_0065007 , obo:GO_1903054 .
obo:RO_0002212 a rdf:Property ;
rdfs:label "negatively regulates"@en ;
rdfs:comment "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002305 , obo:RO_0002211 .
obo:GO_0043556 a rdfs:Class ;
rdfs:label "regulation of translation in response to oxidative stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0032055 , obo:GO_0065007 .
obo:UBERON_0002749 a rdfs:Class ;
rdfs:label "regional part of cerebellar cortex" ;
rdfs:comment "A regional part of brain that is part of a cerebellar cortex [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0002616 .
obo:RO_0000086 a rdf:Property ;
rdfs:label "has quality"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
rdfs:range obo:BFO_0000019 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:GO_0002182 a rdfs:Class ;
rdfs:label "cytoplasmic translational elongation" ;
rdfs:comment "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm." ;
rdfs:subClassOf obo:GO_0006414 .
obo:RO_0004007 a rdf:Property ;
rdfs:label "has primary input or output" ;
rdfs:comment "p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0000057 .
obo:RO_0004008 a rdf:Property ;
rdfs:label "has primary output" ;
rdfs:comment "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0004007 , obo:RO_0002234 .
obo:GO_0006521 a rdfs:Class ;
rdfs:label "regulation of amino acid metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080090 .
obo:GO_0060411 a rdfs:Class ;
rdfs:label "cardiac septum morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart." ;
rdfs:subClassOf obo:GO_0009653 .
obo:RO_0002298 a rdf:Property ;
rdfs:label "results in morphogenesis of"@en ;
rdfs:comment "The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state." ;
rdfs:domain obo:GO_0008150 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0040036 , obo:RO_0002295 .
obo:UBERON_0003063 a rdfs:Class ;
rdfs:label "prechordal plate" ;
rdfs:comment "A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:RO_0002494 a rdf:Property ;
rdfs:label "transformation of" ;
rdfs:comment "x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships" ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002202 .
obo:GO_0060627 a rdfs:Class ;
rdfs:label "regulation of vesicle-mediated transport" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0051049 , obo:GO_0065007 .
obo:GO_0007216 a rdfs:Class ;
rdfs:label "G protein-coupled glutamate receptor signaling pathway" ;
rdfs:comment "A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process." ;
rdfs:subClassOf obo:GO_0007165 , obo:GO_0007186 , obo:GO_0007215 .
obo:RO_0002224 a rdf:Property ;
rdfs:label "starts with"@en ;
rdfs:comment "x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000051 .
obo:PHIPO_0000310 a rdfs:Class ;
rdfs:label "obsolete normal effector of virulence" ;
rdfs:comment "The pathogen has the ability to cause infectious disease dependent upon the gene for gene relationship between the pathogen and host genotype and this is unaltered compared to the wildtype interaction. This may result in disease (virulence) or no disease (avirulence)." .
obo:GO_1900160 a rdfs:Class ;
rdfs:label "plastid chromosome packaging" ;
rdfs:comment "A process in which plastidial DNA and associated proteins organize into a compact, orderly structure." ;
rdfs:subClassOf obo:GO_0051276 .
obo:RO_0002592 a rdf:Property ;
rdfs:label "results in organization of" ;
rdfs:comment "p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c" ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0040036 .
obo:GO_1901861 a rdfs:Class ;
rdfs:label "regulation of muscle tissue development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of muscle tissue development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:CL_4307049 a rdfs:Class ;
rdfs:label "Astro-TE NN_5 Hs3st3a1 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Thbs4 (Mmus), Hs3st3a1 (Mmus), Sfrp1 (Mmus). It is distinguished from other Astro-TE NN_5 cells by expression of Hs3st3a1, Sfrp1. These cells are located in the Olfactory areas, brain , in or close to the regions: Anterior olfactory nucleus, corpus callosum, body, lateral ventricle, corpus callosum, anterior forceps . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5229 Astro-TE NN_5." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301595 .
obo:RO_0015001 a rdf:Property ;
rdfs:label "has exemplar data" ;
rdfs:comment "A relation between a material entity and some data in which the data is taken as exemplifying the material entity." ;
rdfs:range .
a rdfs:Class ;
rdfs:label "brain" ;
rdfs:subClassOf , obo:UBERON_0000955 , obo:UBERON_0008823 .
obo:RO_0002433 a rdf:Property ;
rdfs:label "contributes to morphology of" ;
rdfs:comment "p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm." ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:BSPO_0000123 a rdf:Property ;
rdfs:range .
obo:RO_0002492 a rdf:Property ;
rdfs:label "existence ends during" ;
rdfs:comment "x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y)." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002497 , obo:RO_0002490 .
obo:RO_0002495 a rdf:Property ;
rdfs:label "immediate transformation of" ;
rdfs:comment "x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t" ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002494 , obo:RO_0002207 .
obo:GO_0061668 a rdfs:Class ;
rdfs:label "mitochondrial ribosome assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0042255 .
obo:RO_0002588 a rdf:Property ;
rdfs:label "results in assembly of" ;
rdfs:domain obo:GO_0008150 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002592 , obo:RO_0002297 .
obo:UBERON_0027371 a rdfs:Class ;
rdfs:label "striosome" ;
rdfs:comment "One of two compartments identified in the neostriatum, particularly the caudate nucleus, on the basis of differential staining for several biochemical markers such as acetylcholinesterase and calbindin. In individual sections, the striosomes appear as small patches of differentially high or low staining activity. In three dimensions, they form a 3D labyrinth extending throughout the caudate nucleus and in the putamen." ;
rdfs:subClassOf obo:UBERON_0025736 .
obo:GO_0046173 a rdfs:Class ;
rdfs:label "polyol biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms." ;
rdfs:subClassOf obo:GO_0019751 , obo:GO_0046165 .
obo:GO_0001763 a rdfs:Class ;
rdfs:label "morphogenesis of a branching structure" ;
rdfs:comment "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0032501 .
obo:UBERON_0002190 a rdfs:Class ;
rdfs:label "subcutaneous adipose tissue" ;
rdfs:comment "A portion of adipose tissue that is part of the hypodermis, beneath the dermis." ;
rdfs:subClassOf obo:UBERON_0001013 .
obo:CL_0000025 a rdfs:Class ;
rdfs:label "egg cell" ;
rdfs:comment "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization." ;
rdfs:subClassOf obo:CL_0000675 .
obo:RO_0002216 a rdf:Property ;
rdfs:label "capable of part of"@en ;
rdfs:comment "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002500 , obo:RO_0002328 .
obo:GO_0021533 a rdfs:Class ;
rdfs:label "cell differentiation in hindbrain" ;
rdfs:comment "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0009100 a rdfs:Class ;
rdfs:label "glycoprotein metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0019538 , obo:GO_1901135 .
obo:PHIPO_0000607 a rdfs:Class ;
rdfs:label "resistance to flutriafol"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to flutriafol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0046533 a rdfs:Class ;
rdfs:label "negative regulation of photoreceptor cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0045665 , obo:GO_0046532 , obo:GO_0051241 , obo:GO_0065007 .
obo:CHEBI_55429 a rdfs:Class ;
rdfs:label "cephamycin" ;
rdfs:comment "Any member of the cephamycin sub-group of cephem antibiotics, differing from cephalosporins in possessing a methoxy group at the 7α-position of the cephem nucleus, and in being resistant to β-lactamase." ;
rdfs:subClassOf obo:CHEBI_38311 .
obo:CL_0002606 a rdfs:Class ;
rdfs:label "astrocyte of the spinal cord" ;
rdfs:comment "An astrocyte of the spinal cord." ;
rdfs:subClassOf obo:CL_0000127 .
obo:UBERON_0034707 a rdfs:Class ;
rdfs:label "differentiating neuroepithelium" ;
rdfs:comment "A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells." ;
rdfs:subClassOf obo:UBERON_0034705 .
obo:CHEBI_7528 a rdfs:Class ;
rdfs:label "netilmycin" ;
rdfs:subClassOf obo:CHEBI_22479 , obo:CHEBI_22507 , obo:CHEBI_28079 , obo:CHEBI_63367 .
obo:RO_0018038 a rdf:Property ;
rdfs:range .
obo:GO_0098609 a rdfs:Class ;
rdfs:label "cell-cell adhesion" ;
rdfs:comment "The attachment of one cell to another cell via adhesion molecules." ;
rdfs:subClassOf obo:GO_0007155 .
obo:GO_0060578 a rdfs:Class ;
rdfs:label "superior vena cava morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048845 .
obo:GO_0046621 a rdfs:Class ;
rdfs:label "negative regulation of organ growth" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism." ;
rdfs:subClassOf obo:GO_0046620 , obo:GO_0048640 , obo:GO_0051241 , obo:GO_0065007 .
obo:CHEBI_26416 a rdfs:Class ;
rdfs:label "pyridine alkaloid" ;
rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_26421 .
obo:CHEBI_140325 a rdfs:Class ;
rdfs:label "secondary carboxamide" ;
rdfs:comment "A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR1." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:CHEBI_87197 a rdfs:Class ;
rdfs:label "dichlorophenyl dicarboximide fungicide" ;
rdfs:comment "A dicarboximide fungicide in which the nitrogen of the dicarboximide group is substituted by a dichlorophenyl group." ;
rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_87195 .
obo:UBERON_0019258 a rdfs:Class ;
rdfs:label "white matter of hindbrain" ;
rdfs:comment "A white matter that is part of the hindbrain." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0003544 .
obo:GO_1905208 a rdfs:Class ;
rdfs:label "negative regulation of cardiocyte differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1905207 .
obo:UBERON_0003931 a rdfs:Class ;
rdfs:label "diencephalic white matter" ;
rdfs:comment "White matter that is part of a diencephalon [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0019261 .
obo:CL_0000353 a rdfs:Class ;
rdfs:label "blastoderm cell" ;
rdfs:comment "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)." ;
rdfs:subClassOf obo:CL_0000007 .
obo:CHEBI_2682 a rdfs:Class ;
rdfs:label "amphotericin B" ;
rdfs:comment "A macrolide antibiotic used to treat potentially life-threatening fungal infections." ;
rdfs:subClassOf obo:CHEBI_25105 , obo:CHEBI_26177 , obo:CHEBI_61355 , obo:CHEBI_87113 .
obo:RO_0018034 a rdf:Property ;
rdfs:range .
a rdf:Property ;
rdfs:range .
obo:PHIPO_0000953 a rdfs:Class ;
rdfs:label "pathogen penetration structure present when near host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the pathogen specialized host penetration structure is present." ;
rdfs:subClassOf obo:PHIPO_0000352 .
obo:UBERON_0000087 a rdfs:Class ;
rdfs:label "inner cell mass" ;
rdfs:comment "A mass of cells that develop into the body of the embryo and some extraembryonic tissues." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:RO_0002219 a rdf:Property ;
rdfs:label "surrounded by"@en ;
rdfs:comment "x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x" ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002220 .
obo:UBERON_1100000 a rdfs:Class ;
rdfs:label "digestive tract junction" ;
rdfs:comment "An anatomical junction between two parts of the digestive tract." ;
rdfs:subClassOf obo:UBERON_0007651 .
obo:CHEBI_27242 a rdfs:Class ;
rdfs:label "uridines" ;
rdfs:subClassOf obo:CHEBI_39446 .
a rdf:Property ;
rdfs:range .
obo:UBERON_0001645 a rdfs:Class ;
rdfs:label "trigeminal nerve" ;
rdfs:comment "Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw)." ;
rdfs:subClassOf obo:UBERON_0001785 .
obo:BSPO_0000126 a rdf:Property ;
rdfs:range .
a rdf:Property ;
rdfs:label "extends_fibers_into" ;
rdfs:comment "X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y" ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002170 .
obo:BSPO_0000096 a rdf:Property ;
rdfs:range .
obo:RO_0002134 a rdf:Property ;
rdfs:label "innervates"@en ;
rdfs:comment """Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input.
T innervates some R
Expands_to: T has_fasciculating_neuron_projection that synapse_in some R."""@en ;
rdfs:domain obo:UBERON_0000122 ;
rdfs:range .
obo:GO_0042176 a rdfs:Class ;
rdfs:label "regulation of protein catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0051246 , obo:GO_0065007 .
obo:GO_0023023 a rdfs:Class ;
rdfs:label "MHC protein complex binding" ;
rdfs:comment "Binding to a major histocompatibility complex." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0044877 .
obo:RO_0004009 a rdf:Property ;
rdfs:label "has primary input" ;
rdfs:comment "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0004007 , obo:RO_0002233 .
obo:PR_P06879 a rdfs:Class ;
rdfs:label "prolactin (mouse)" ;
rdfs:comment "A prolactin that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000013246 , obo:PR_000029032 .
obo:RO_0018040 a rdf:Property ;
rdfs:range .
a rdf:Property ;
rdfs:range .
obo:RO_0020337 a rdf:Property ;
rdfs:label "has constituent monomer" ;
rdfs:comment "A relation that holds between a polymer and its constituent monomers. P has_constituent_monomer 'm' if and only if P has_component multiple instances of 'm' and each instance of 'm' is covalently attached to another instance of 'm'."@en ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002180 .
a rdf:Property ;
rdfs:range .
a rdf:Property ;
rdfs:range .
obo:RO_0002160 a rdf:Property ;
rdfs:label "only in taxon" ;
rdfs:comment "x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z." ;
rdfs:range obo:OBI_0100026 ;
rdfs:subPropertyOf obo:RO_0002162 .
obo:GO_0016052 a rdfs:Class ;
rdfs:label "carbohydrate catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." ;
rdfs:subClassOf obo:GO_0005975 , obo:GO_0009056 .
obo:CHEBI_77056 a rdfs:Class ;
rdfs:label "(R)-closantel" ;
rdfs:comment "An N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide that has R configuration." ;
rdfs:subClassOf obo:CHEBI_77054 .
obo:GO_0031116 a rdfs:Class ;
rdfs:label "positive regulation of microtubule polymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." ;
rdfs:subClassOf obo:GO_0031112 , obo:GO_0031113 , obo:GO_0032273 , obo:GO_0065007 , obo:GO_1902905 .
obo:RO_0002213 a rdf:Property ;
rdfs:label "positively regulates"@en ;
rdfs:comment "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002304 , obo:RO_0002211 .
obo:CL_0011022 a rdfs:Class ;
rdfs:label "fibroblast of skin of back" ;
rdfs:comment "A fibroblast that is part of skin of back." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0002620 .
obo:PHIPO_0000982 a rdfs:Class ;
rdfs:label "normal meiosis"@en ;
rdfs:comment "A reproductive process phenotype in which the meiotic nuclear divisions are normal (i.e. indistinguishable from wild type). (GO:0140013)." ;
rdfs:subClassOf obo:PHIPO_0000984 .
obo:CHEBI_51689 a rdfs:Class ;
rdfs:label "enone" ;
rdfs:comment "An α,β-unsaturated ketone of general formula R1R2C=CR3‒C(=O)R4 (R4 ≠ H) in which the C=O function is conjugated to a C=C double bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_51721 , obo:CHEBI_78840 .
obo:PHIPO_0001354 a rdfs:Class ;
rdfs:label "sensitive to prothioconazole" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to prothioconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PR_000001832 a rdfs:Class ;
rdfs:label "SIRP/SHPS-1 family protein" ;
rdfs:comment "A protein with core architecture consisting of a signal sequence, one Immunoglobulin V-set domain (Pfam:PF07686), two Immunoglobulin C1-set domains (Pfam:PF07654), a single-pass transmembrane region and a very small cytoplasmic region." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:NCBITaxon_117571 a rdfs:Class ;
rdfs:label "Euteleostomi" ;
rdfs:subClassOf obo:NCBITaxon_117570 .
obo:GO_0010831 a rdfs:Class ;
rdfs:label "positive regulation of myotube differentiation" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ;
rdfs:subClassOf obo:GO_0010830 , obo:GO_0051155 , obo:GO_0065007 .
obo:GO_0048048 a rdfs:Class ;
rdfs:label "embryonic eye morphogenesis" ;
rdfs:comment "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized." ;
rdfs:subClassOf obo:GO_0048562 , obo:GO_0048592 .
obo:GO_0045619 a rdfs:Class ;
rdfs:label "regulation of lymphocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." ;
rdfs:subClassOf obo:GO_0051249 , obo:GO_0065007 , obo:GO_1902105 .
obo:GO_0006023 a rdfs:Class ;
rdfs:label "aminoglycan biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." ;
rdfs:subClassOf obo:GO_0006022 , obo:GO_0009058 , obo:GO_0009059 , obo:GO_1901137 .
obo:GO_1990280 a rdfs:Class ;
rdfs:label "RNA localization to chromatin" ;
rdfs:comment "A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin." ;
rdfs:subClassOf obo:GO_0006403 .
obo:RO_0002339 a rdf:Property ;
rdfs:label "has target end location"@en ;
rdfs:comment "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002344 .
obo:CHEBI_3405 a rdfs:Class ;
rdfs:label "carboxin" ;
rdfs:comment "An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acid. A fungicide for control of bunts and smuts that is normally used as a seed treatment." ;
rdfs:subClassOf obo:CHEBI_13248 , obo:CHEBI_140325 , obo:CHEBI_38104 , obo:CHEBI_38106 , obo:CHEBI_51751 , obo:CHEBI_87015 .
obo:GO_1904675 a rdfs:Class ;
rdfs:label "regulation of somatic stem cell division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of somatic stem cell division." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000035 .
obo:GO_0070160 a rdfs:Class ;
rdfs:label "tight junction" ;
rdfs:comment "A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." ;
rdfs:subClassOf obo:GO_0005911 .
obo:GO_1903019 a rdfs:Class ;
rdfs:label "negative regulation of glycoprotein metabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process." ;
rdfs:subClassOf obo:GO_0051248 , obo:GO_0065007 , obo:GO_1903018 .
obo:GO_0034392 a rdfs:Class ;
rdfs:label "negative regulation of smooth muscle cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process." ;
rdfs:subClassOf obo:GO_0010656 , obo:GO_0034391 , obo:GO_0065007 .
obo:UBERON_0004905 a rdfs:Class ;
rdfs:label "articulation" ;
rdfs:comment "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." ;
rdfs:subClassOf obo:UBERON_0034921 .
obo:GO_1905331 a rdfs:Class ;
rdfs:label "negative regulation of morphogenesis of an epithelium" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0065007 , obo:GO_1905330 .
obo:GO_0014025 a rdfs:Class ;
rdfs:label "neural keel formation" ;
rdfs:comment "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts." ;
rdfs:subClassOf obo:GO_0048646 .
obo:RO_0002297 a rdf:Property ;
rdfs:label "results in formation of"@en ;
rdfs:domain obo:GO_0008150 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002234 , obo:RO_0002295 , obo:IDO_0000660 .
obo:PATO_0002288 a rdfs:Class ;
rdfs:label "decreased elasticity" ;
rdfs:comment "An elasticity which is relatively low." ;
rdfs:subClassOf obo:PATO_0001171 , obo:PATO_0002303 .
obo:RO_0002573 a rdf:Property ;
rdfs:label "has modifier" ;
rdfs:comment "A relation that holds between an attribute or a qualifier and another attribute." ;
rdfs:domain obo:BFO_0000020 ;
rdfs:range obo:BFO_0000020 .
a rdf:Property ;
rdfs:label "obsolete decreased_in_magnitude_relative_to" ;
rdfs:comment "OBSOLETE. q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." ;
rdfs:domain obo:PATO_0000001 ;
rdfs:range obo:PATO_0000001 .
obo:RO_0015006 a rdf:Property ;
rdfs:label "different in magnitude relative to" ;
rdfs:comment "q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." ;
rdfs:domain obo:PATO_0000001 ;
rdfs:range obo:PATO_0000001 .
obo:RO_0015007 a rdf:Property ;
rdfs:label "increased in magnitude relative to" ;
rdfs:comment "q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." ;
rdfs:domain obo:PATO_0000001 ;
rdfs:range obo:PATO_0000001 ;
rdfs:subPropertyOf obo:RO_0015006 .
a rdf:Property ;
rdfs:label "obsolete increased_in_magnitude_relative_to" ;
rdfs:comment "OBSOLETE. q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." ;
rdfs:domain obo:PATO_0000001 ;
rdfs:range obo:PATO_0000001 .
obo:RO_0015008 a rdf:Property ;
rdfs:label "decreased in magnitude relative to" ;
rdfs:comment "q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." ;
rdfs:domain obo:PATO_0000001 ;
rdfs:range obo:PATO_0000001 ;
rdfs:subPropertyOf obo:RO_0015006 .
obo:GO_1905558 a rdfs:Class ;
rdfs:label "negative regulation of mitotic nuclear envelope disassembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0051129 , obo:GO_0065007 , obo:GO_1905557 .
obo:UBERON_0009479 a rdfs:Class ;
rdfs:label "ectoderm of buccopharyngeal membrane" ;
rdfs:comment "An ectoderm that is part of a buccopharyngeal membrane." ;
rdfs:subClassOf obo:UBERON_0000924 .
obo:GO_1905871 a rdfs:Class ;
rdfs:label "regulation of protein localization to cell leading edge" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to cell leading edge." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_2000108 a rdfs:Class ;
rdfs:label "positive regulation of leukocyte apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0065007 , obo:GO_2000106 .
obo:GO_0045648 a rdfs:Class ;
rdfs:label "positive regulation of erythrocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045639 , obo:GO_0045646 , obo:GO_0065007 .
obo:GO_0005488 a rdfs:Class ;
rdfs:label "binding" ;
rdfs:comment "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf obo:GO_0003674 .
obo:GO_0009532 a rdfs:Class ;
rdfs:label "plastid stroma" ;
rdfs:comment "The proteinaceous ground substance of plastids." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0008643 a rdfs:Class ;
rdfs:label "carbohydrate transport" ;
rdfs:comment "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y." ;
rdfs:subClassOf obo:GO_0006810 .
obo:CHEBI_33554 a rdfs:Class ;
rdfs:label "organosulfonate oxoanion" ;
rdfs:comment "An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:RO_0018033 a rdf:Property ;
rdfs:range .
obo:GO_0035290 a rdfs:Class ;
rdfs:label "trunk segmentation" ;
rdfs:comment "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8." ;
rdfs:subClassOf obo:GO_0035282 .
obo:UBERON_0036186 a rdfs:Class ;
rdfs:label "fibroelastic connective tissue" ;
rdfs:subClassOf obo:UBERON_0002521 , obo:UBERON_0011824 .
obo:CL_0000036 a rdfs:Class ;
rdfs:label "epithelial fate stem cell" ;
rdfs:comment "A somatic stem cell that is committed to an epithelial fate, possessing the capacity for self-renewal and the ability to differentiate into one or more distinct mature cell types of the epithelial lineage. This cell is crucial for the development, homeostasis, repair, and regeneration of epithelial tissues." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000723 .
obo:CHEBI_64256 a rdfs:Class ;
rdfs:label "tunicamycin C1" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 14-methylpentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:CL_0000306 a rdfs:Class ;
rdfs:label "crystallin accumulating cell" ;
rdfs:subClassOf obo:CL_0000325 .
obo:GO_0021646 a rdfs:Class ;
rdfs:label "vagus nerve formation" ;
rdfs:comment "The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." ;
rdfs:subClassOf obo:GO_0021603 , obo:GO_0048646 .
obo:UBERON_0036352 a rdfs:Class ;
rdfs:label "wall of subclavian artery" ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0000415 .
obo:PHIPO_0000596 a rdfs:Class ;
rdfs:label "resistance to eflornithine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to eflornithine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0006222 a rdfs:Class ;
rdfs:label "future diencephalon" ;
rdfs:comment "The foremost region of the future forebrain that develops into the diencephalon." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:RO_0002387 a rdf:Property ;
rdfs:label "has potential to develop into"@en ;
rdfs:comment "x has the potential to develop into y iff x develops into y or if x is capable of developing into y"@en ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002384 .
obo:GO_1904951 a rdfs:Class ;
rdfs:label "positive regulation of establishment of protein localization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of establishment of protein localization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070201 , obo:GO_1903829 .
obo:GO_0051494 a rdfs:Class ;
rdfs:label "negative regulation of cytoskeleton organization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0051493 , obo:GO_0065007 .
obo:CL_0000192 a rdfs:Class ;
rdfs:label "smooth muscle cell" ;
rdfs:comment "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." ;
rdfs:subClassOf obo:CL_0008000 , obo:CL_0008007 .
obo:GO_0048855 a rdfs:Class ;
rdfs:label "adenohypophysis morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0036094 a rdfs:Class ;
rdfs:label "small molecule binding" ;
rdfs:comment "Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule." ;
rdfs:subClassOf obo:GO_0005488 .
obo:GO_0060502 a rdfs:Class ;
rdfs:label "epithelial cell proliferation involved in lung morphogenesis" ;
rdfs:comment "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung." ;
rdfs:subClassOf obo:GO_0050673 .
obo:RO_0012003 a rdf:Property ;
rdfs:label "acts on population of"@en ;
rdfs:comment "p acts on population of c iff c' is a collection, has members of type c, and p has participant c" ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0000057 .
obo:NCBITaxon_337687 a rdfs:Class ;
rdfs:label "Muroidea" ;
rdfs:subClassOf obo:NCBITaxon_1963758 .
obo:GO_0021863 a rdfs:Class ;
rdfs:label "forebrain neuroblast differentiation" ;
rdfs:comment "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0014016 , obo:GO_0030154 .
obo:CHEBI_17029 a rdfs:Class ;
rdfs:label "chitin" ;
rdfs:comment "An aminoglycan consisting of β-(1→4)-linked N-acetyl-D-glucosamine residues." ;
rdfs:subClassOf obo:CHEBI_21638 , obo:CHEBI_22506 .
obo:CL_4028001 a rdfs:Class ;
rdfs:label "pulmonary capillary endothelial cell" ;
rdfs:comment "Any capillary endothelial cell that is part of a lung." ;
rdfs:subClassOf obo:CL_0002144 , obo:CL_2000016 .
obo:GO_0007548 a rdfs:Class ;
rdfs:label "sex differentiation" ;
rdfs:comment "The establishment of the sex of an organism by physical differentiation." ;
rdfs:subClassOf obo:GO_0003006 .
obo:CHEBI_51373 a rdfs:Class ;
rdfs:label "GABA agonist" ;
rdfs:comment "A drug that binds to and activates γ-aminobutyric acid receptors." ;
rdfs:subClassOf obo:CHEBI_51374 .
obo:UBERON_0009722 a rdfs:Class ;
rdfs:label "entire pharyngeal arch endoderm" ;
rdfs:subClassOf obo:UBERON_0005291 , obo:UBERON_0005911 , obo:UBERON_0015833 .
obo:GO_1905268 a rdfs:Class ;
rdfs:label "negative regulation of chromatin organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1902275 .
obo:CHEBI_38215 a rdfs:Class ;
rdfs:label "calcium channel blocker" ;
rdfs:comment "One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools." ;
rdfs:subClassOf obo:CHEBI_38808 , obo:CHEBI_48706 .
obo:GO_0045764 a rdfs:Class ;
rdfs:label "positive regulation of amino acid metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." ;
rdfs:subClassOf obo:GO_0006521 , obo:GO_0009893 , obo:GO_0065007 .
obo:UBERON_0001533 a rdfs:Class ;
rdfs:label "subclavian artery" ;
rdfs:comment "One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0004573 .
obo:RO_0020101 a rdf:Property ;
rdfs:label "vessel supplies blood to" ;
rdfs:comment "x vessel supplies blood to y if and only if x is a vessel that supplies blood directly or indirectly to an anatomical structure y." ;
rdfs:domain obo:UBERON_0001981 ;
rdfs:range obo:UBERON_0000061 ;
rdfs:subPropertyOf obo:RO_0002178 .
obo:RO_0002131 a rdf:Property ;
rdfs:label "overlaps"@en ;
rdfs:comment "x overlaps y if and only if there exists some z such that x has part z and z part of y" ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002323 .
a rdf:Property ;
rdfs:label "channels_from" ;
rdfs:range .
obo:RO_0020102 a rdf:Property ;
rdfs:label "vessel drains blood from" ;
rdfs:comment "x vessel drains blood from y if and only if x is a vessel that drains blood directly or indirectly from an anatomical structure y." ;
rdfs:domain obo:UBERON_0001981 ;
rdfs:range obo:UBERON_0000061 ;
rdfs:subPropertyOf obo:RO_0002179 .
obo:RO_0002170 a rdf:Property ;
rdfs:label "connected to"@en ;
rdfs:comment "a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b" ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002323 .
a rdf:Property ;
rdfs:label "channel for" ;
rdfs:domain obo:UBERON_0004111 ;
rdfs:range obo:UBERON_0000463 .
obo:GO_0106214 a rdfs:Class ;
rdfs:label "regulation of vesicle fusion with Golgi apparatus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus." ;
rdfs:subClassOf obo:GO_0031338 , obo:GO_0065007 , obo:GO_1903358 .
obo:UBERON_0019292 a rdfs:Class ;
rdfs:label "white matter of pons" ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0014891 , obo:UBERON_0019291 .
obo:GO_0014052 a rdfs:Class ;
rdfs:label "regulation of gamma-aminobutyric acid secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." ;
rdfs:subClassOf obo:GO_0032890 , obo:GO_0051046 , obo:GO_0051955 , obo:GO_0065007 .
obo:GO_1905306 a rdfs:Class ;
rdfs:label "positive regulation of cardiac myofibril assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051495 , obo:GO_0065007 , obo:GO_1902117 , obo:GO_1902905 , obo:GO_1905304 .
obo:GO_0071622 a rdfs:Class ;
rdfs:label "regulation of granulocyte chemotaxis" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0002688 , obo:GO_0065007 .
obo:GO_0060612 a rdfs:Class ;
rdfs:label "adipose tissue development" ;
rdfs:comment "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0061448 .
obo:RO_0002296 a rdf:Property ;
rdfs:label "results in development of"@en ;
rdfs:comment "p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state." ;
rdfs:domain obo:GO_0008150 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0040036 , obo:RO_0002295 .
obo:CHEBI_15354 a rdfs:Class ;
rdfs:label "choline" ;
rdfs:comment "A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function." ;
rdfs:subClassOf obo:CHEBI_23217 .
obo:GO_1905476 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to membrane" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903828 , obo:GO_1905475 .
obo:GO_0060973 a rdfs:Class ;
rdfs:label "cell migration involved in heart development" ;
rdfs:comment "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ." ;
rdfs:subClassOf obo:GO_0016477 .
obo:GO_0097576 a rdfs:Class ;
rdfs:label "vacuole fusion" ;
rdfs:comment "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole." ;
rdfs:subClassOf obo:GO_0007033 , obo:GO_0009987 , obo:GO_0048284 .
obo:RO_0012008 a rdf:Property ;
rdfs:label "results in fusion of"@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002592 .
obo:PHIPO_0000754 a rdfs:Class ;
rdfs:label "sensitive to leptomycin B"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to leptomycin B. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0009841 a rdfs:Class ;
rdfs:label "upper rhombic lip" ;
rdfs:comment "Anterior-most region of dorsal hindbrain within rhombomere 1, adjacent the midbrain-hindbrain boundary." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:PHIPO_0000719 a rdfs:Class ;
rdfs:label "sensitive to fusidic acid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fusidic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1901161 a rdfs:Class ;
rdfs:label "primary amino compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of primary amino compound." ;
rdfs:subClassOf obo:GO_0009056 .
obo:CHEBI_87100 a rdfs:Class ;
rdfs:label "triazole fungicide" ;
rdfs:comment "Any triazole antifungal agent that has been used as a fungicide." ;
rdfs:subClassOf obo:CHEBI_86426 .
obo:CHEBI_63046 a rdfs:Class ;
rdfs:label "emulsifier" ;
rdfs:comment "The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:BFO_0000034 a rdfs:Class ;
rdfs:label "function"@en ;
rdfs:subClassOf obo:BFO_0000016 .
obo:BFO_0000054 a rdf:Property ;
rdfs:label "realized in"@en ;
rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
rdfs:domain obo:BFO_0000017 ;
rdfs:range obo:BFO_0000015 .
obo:RO_0000079 a rdf:Property ;
rdfs:label "function of"@en ;
rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000034 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:CHEBI_33318 a rdfs:Class ;
rdfs:label "main group element atom" ;
rdfs:comment "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:UBERON_0004237 a rdfs:Class ;
rdfs:label "blood vessel smooth muscle" ;
rdfs:comment "Smooth muscle found within, and composing the majority of the wall of blood vessels." ;
rdfs:subClassOf obo:UBERON_0001135 .
obo:CHEBI_39230 a rdfs:Class ;
rdfs:label "emamectin" ;
rdfs:comment "A mixture of emamectin B1a (major component) and emamectin B1b (minor component)." ;
rdfs:subClassOf obo:CHEBI_39213 .
obo:PHIPO_0001348 a rdfs:Class ;
rdfs:label "resistance to pyrifenox" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to pyrifenox. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1905349 a rdfs:Class ;
rdfs:label "ciliary transition zone assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone." ;
rdfs:subClassOf obo:GO_0022607 .
obo:GO_0045779 a rdfs:Class ;
rdfs:label "negative regulation of bone resorption" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption." ;
rdfs:subClassOf obo:GO_0045124 , obo:GO_0046851 , obo:GO_0065007 .
obo:GO_1903748 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to mitochondrion" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitochondrion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903747 , obo:GO_1903828 .
obo:CHEBI_64255 a rdfs:Class ;
rdfs:label "tunicamycin B3" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 13-methyltetradecanoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:UBERON_0010378 a rdfs:Class ;
rdfs:label "mesenchyme from splanchnopleure" ;
rdfs:comment "Mesenchyme that develops_from a splanchnopleure." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005291 , obo:UBERON_0007524 .
obo:RO_0002328 a rdf:Property ;
rdfs:label "functionally related to"@en ;
rdfs:comment "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." ;
rdfs:range .
obo:GO_1901589 a rdfs:Class ;
rdfs:label "axon microtubule bundle" ;
rdfs:comment "An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment." ;
rdfs:subClassOf obo:GO_0097427 .
obo:GO_0021872 a rdfs:Class ;
rdfs:label "forebrain generation of neurons" ;
rdfs:comment "The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons." ;
rdfs:subClassOf obo:GO_0048699 .
obo:CHEBI_88227 a rdfs:Class ;
rdfs:label "potassium ionophore" ;
rdfs:comment "Any ionophore capable of transportation of potassium ions across membranes." ;
rdfs:subClassOf obo:CHEBI_24869 .
obo:GO_0098657 a rdfs:Class ;
rdfs:label "import into cell" ;
rdfs:comment "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." ;
rdfs:subClassOf obo:GO_0006810 .
obo:RO_0002338 a rdf:Property ;
rdfs:label "has target start location"@en ;
rdfs:comment "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002344 .
obo:GO_1904027 a rdfs:Class ;
rdfs:label "negative regulation of collagen fibril organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903054 , obo:GO_1904026 .
obo:PHIPO_0000823 a rdfs:Class ;
rdfs:label "sensitive to cercosporamide"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cercosporamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PATO_0002303 a rdfs:Class ;
rdfs:label "decreased object quality" ;
rdfs:comment "A quality of an object that has a value that is decreased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0001241 , obo:PATO_0002301 .
obo:PHIPO_0000765 a rdfs:Class ;
rdfs:label "sensitive to methicillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to methicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:BFO_0000017 a rdfs:Class ;
rdfs:label "realizable entity"@en ;
rdfs:comment "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
rdfs:subClassOf obo:BFO_0000020 .
obo:UBERON_0014398 a rdfs:Class ;
rdfs:label "respiratory muscle" ;
rdfs:comment "Muscle that is part of the respiratory system." ;
rdfs:subClassOf obo:UBERON_0001630 , obo:UBERON_0003831 .
obo:UBERON_0002104 a rdfs:Class ;
rdfs:label "visual system" ;
rdfs:comment "The sensory system subserving the sense of vision." ;
rdfs:subClassOf obo:UBERON_0001032 .
obo:RO_0002180 a rdf:Property ;
rdfs:label "has component"@en ;
rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
rdfs:range ;
rdfs:subPropertyOf obo:BFO_0000051 .
obo:CHEBI_64571 a rdfs:Class ;
rdfs:label "NMDA receptor agonist" ;
rdfs:comment "An excitatory amino acid agonist which binds to NMDA receptors and triggers a response." ;
rdfs:subClassOf obo:CHEBI_50103 .
obo:GO_1901716 a rdfs:Class ;
rdfs:label "negative regulation of GABA catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0045763 , obo:GO_0062014 , obo:GO_0065007 , obo:GO_1901715 .
obo:UBERON_0010341 a rdfs:Class ;
rdfs:label "1st arch mesenchyme from head mesenchyme" ;
rdfs:comment "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0010042 , obo:UBERON_0010360 .
obo:PHIPO_0000410 a rdfs:Class ;
rdfs:label "decreased asexual spore germination frequency"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of asexual spore germination is decreased." ;
rdfs:subClassOf obo:PHIPO_0000509 .
obo:CL_0000598 a rdfs:Class ;
rdfs:label "pyramidal neuron" ;
rdfs:comment "Pyramidal neurons have a pyramid-shaped soma with a single axon, a large apical dendrite and multiple basal dendrites. The apex and an apical dendrite typically point toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000029 .
obo:RO_0002130 a rdf:Property ;
rdfs:label "has synaptic terminal in"@en ;
rdfs:comment "A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input." ;
rdfs:domain obo:CL_0000540 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0002100 a rdf:Property ;
rdfs:label "has soma location" ;
rdfs:comment "Relation between a neuron and a material anatomical entity that its soma is part of."@en ;
rdfs:domain obo:CL_0000540 ;
rdfs:range obo:UBERON_0000465 ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0002113 a rdf:Property ;
rdfs:label "has presynaptic terminal in"@en ;
rdfs:comment "Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input."@en ;
rdfs:domain obo:CL_0000540 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002130 .
obo:RO_0020104 a rdf:Property ;
rdfs:label "is neuron" ;
rdfs:comment "This property only applies to neurons" ;
rdfs:domain obo:CL_0000540 ;
rdfs:range .
obo:RO_0002110 a rdf:Property ;
rdfs:label "has postsynaptic terminal in"@en ;
rdfs:comment "Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. "@en ;
rdfs:domain obo:CL_0000540 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002130 .
obo:CHEBI_233423 a rdfs:Class ;
rdfs:label "antifibrotic agent" ;
rdfs:comment "Any agent which acts to reduce fibrosis." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:UBERON_0004797 a rdfs:Class ;
rdfs:label "blood vessel layer" ;
rdfs:comment "Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:GO_0006998 a rdfs:Class ;
rdfs:label "nuclear envelope organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0061024 .
obo:CHEBI_53559 a rdfs:Class ;
rdfs:label "topoisomerase IV inhibitor" ;
rdfs:comment "A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands." ;
rdfs:subClassOf obo:CHEBI_70727 .
obo:PHIPO_0000267 a rdfs:Class ;
rdfs:label "abnormal vacuolar transport"@en ;
rdfs:comment "A single organism cellular process phenotype in which vacuolar transport is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000257 , obo:PHIPO_0000929 .
obo:GO_0014812 a rdfs:Class ;
rdfs:label "muscle cell migration" ;
rdfs:comment "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism." ;
rdfs:subClassOf obo:GO_0016477 .
obo:RO_0002565 a rdf:Property ;
rdfs:label "results in movement of" ;
rdfs:comment "Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c" ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0040036 .
obo:CL_4030048 a rdfs:Class ;
rdfs:label "striosomal D1 medium spiny neuron" ;
rdfs:comment "A DRD1-expressing medium spiny neuron that is part of a striosome of dorsal striatum." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_4023026 .
obo:RO_0002292 a rdf:Property ;
rdfs:label "expresses" ;
rdfs:comment "y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process." ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002330 .
obo:GO_1900408 a rdfs:Class ;
rdfs:label "negative regulation of cellular response to oxidative stress" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0065007 , obo:GO_1900407 , obo:GO_1902883 .
obo:PHIPO_0000393 a rdfs:Class ;
rdfs:label "sensitive to oxolinic acid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to oxolinic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0009583 a rdfs:Class ;
rdfs:label "detection of light stimulus" ;
rdfs:comment "The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0009416 , obo:GO_0009581 , obo:GO_0009582 .
obo:UBERON_0001685 a rdfs:Class ;
rdfs:label "hyoid bone" ;
rdfs:comment "A horseshoe shaped bone situated in the anterior midline of the neck between the chin and the thyroid cartilage. The hyoid bone provides attachment to the muscles of the floor of the mouth and the tongue above, the larynx below, and the epiglottis and pharynx behind. [WP,modified]." ;
rdfs:subClassOf obo:UBERON_0008001 .
obo:GO_0021753 a rdfs:Class ;
rdfs:label "superior salivary nucleus development" ;
rdfs:comment "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0021751 , obo:GO_0048856 .
obo:PHIPO_0001004 a rdfs:Class ;
rdfs:label "normal pathogen morphology during colonization of host"@en ;
rdfs:comment "A pathogen host interaction phenotype where the morphology of the pathogen during host colonization is normal (indistinguishable from wild type). This relates to the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0000998 .
obo:GO_0051966 a rdfs:Class ;
rdfs:label "regulation of synaptic transmission, glutamatergic" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 .
obo:GO_1905037 a rdfs:Class ;
rdfs:label "autophagosome organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome." ;
rdfs:subClassOf obo:GO_0007033 .
obo:PHIPO_0001079 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction pigment phenotype" ;
rdfs:comment "A pathogen host interaction organism level phenotype affecting the deposition or aggregation of coloring matter in a cell." .
obo:GO_0021830 a rdfs:Class ;
rdfs:label "interneuron migration from the subpallium to the cortex" ;
rdfs:comment "The directed movement of interneurons from the subpallium to the cortex during forebrain development." ;
rdfs:subClassOf obo:GO_0021843 .
obo:RO_0002344 a rdf:Property ;
rdfs:label "results in transport to from or in"@en ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002337 .
obo:PATO_0002299 a rdfs:Class ;
rdfs:label "tubular" ;
rdfs:comment "A cylindrical shape that is hollow." ;
rdfs:subClassOf obo:PATO_0001873 , obo:PATO_0002078 .
obo:RO_0015011 a rdf:Property ;
rdfs:label "has cross section" ;
rdfs:comment "s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2." ;
rdfs:range .
obo:UBERON_0000465 a rdfs:Class ;
rdfs:label "material anatomical entity" ;
rdfs:comment "Anatomical entity that has mass." ;
rdfs:subClassOf obo:BFO_0000040 , obo:UBERON_0001062 .
obo:PHIPO_0000708 a rdfs:Class ;
rdfs:label "resistance to cephalexin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cephalexin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001299 a rdfs:Class ;
rdfs:label "normal growth on pyrrolnitrin"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrrolnitrin (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:UBERON_0016549 a rdfs:Class ;
rdfs:label "central nervous system white matter layer" ;
rdfs:comment "A layer of of the central nervous system that is composed of white matter." ;
rdfs:subClassOf obo:UBERON_0022303 .
obo:PATO_0000964 a rdfs:Class ;
rdfs:label "transparent" ;
rdfs:comment "A optical quality inhering in a bearer by virtue of the bearer's lacking opacity." ;
rdfs:subClassOf obo:PATO_0000957 .
obo:GO_0021722 a rdfs:Class ;
rdfs:label "superior olivary nucleus maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:RO_0002299 a rdf:Property ;
rdfs:label "results in maturation of"@en ;
rdfs:comment "The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity." ;
rdfs:domain obo:GO_0008150 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0040036 , obo:RO_0002295 .
obo:GO_0061792 a rdfs:Class ;
rdfs:label "secretory granule maturation" ;
rdfs:comment "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0033363 , obo:GO_0071695 .
obo:GO_2000138 a rdfs:Class ;
rdfs:label "positive regulation of cell proliferation involved in heart morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0065007 , obo:GO_2000136 .
obo:PHIPO_0001236 a rdfs:Class ;
rdfs:label "effector-mediated suppression of host effector triggered immunity absent"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion initially induced by the host activating its own hypersensitive response in defense, is subsequently not suppressed by a pathogen effector." ;
rdfs:subClassOf obo:PHIPO_0001176 .
obo:PHIPO_0001207 a rdfs:Class ;
rdfs:label "normal filament length"@en ;
rdfs:comment "A single species cell morphology phenotype where the length of hyphal filaments are normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001206 .
obo:UBERON_0010225 a rdfs:Class ;
rdfs:label "thalamic complex" ;
rdfs:comment "A nuclear complex which in mammals consists of four parts, the hypothalamus, epithalamus, ventral thalamus, and dorsal thalamus[WP,modified]." ;
rdfs:subClassOf obo:UBERON_0007245 , obo:UBERON_0019269 .
obo:CHEBI_82894 a rdfs:Class ;
rdfs:label "(R)-miconazole" ;
rdfs:comment "A 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that has R configuration." ;
rdfs:subClassOf obo:CHEBI_82892 .
obo:RO_0018039 a rdf:Property ;
rdfs:range .
obo:GO_0019336 a rdfs:Class ;
rdfs:label "phenol-containing compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0018958 .
obo:GO_1901505 a rdfs:Class ;
rdfs:label "carbohydrate derivative transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of carbohydrate derivative from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 .
obo:RO_0002342 a rdf:Property ;
rdfs:label "results in transport across"@en ;
rdfs:comment "Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002344 , obo:RO_0002021 .
obo:CHEBI_30347 a rdfs:Class ;
rdfs:label "ethylenediamine" ;
rdfs:comment "An alkane-α,ω-diamine in which the alkane is ethane." ;
rdfs:subClassOf obo:CHEBI_35411 .
obo:GO_1905941 a rdfs:Class ;
rdfs:label "positive regulation of gonad development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of gonad development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1905939 , obo:GO_2000243 .
obo:CHEBI_83876 a rdfs:Class ;
rdfs:label "cationic sphingoid" ;
rdfs:comment "An organic cation obtained by protonation of the amino function of any sphingoid" ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_0140640 a rdfs:Class ;
rdfs:label "catalytic activity, acting on a nucleic acid" ;
rdfs:comment "Catalytic activity that acts to modify a nucleic acid." ;
rdfs:subClassOf obo:GO_0003824 .
obo:PHIPO_0000895 a rdfs:Class ;
rdfs:label "sensitive to mancozeb"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to mancozeb. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_87127 a rdfs:Class ;
rdfs:label "allylamine antifungal drug" ;
rdfs:comment "An organonitrogen compound that contains an amino group that is attached to a carbon which is itself attached to an olefinic carbon and which has been used as an antifungal drug." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:GO_0060283 a rdfs:Class ;
rdfs:label "negative regulation of oocyte development" ;
rdfs:comment "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0060281 , obo:GO_0065007 , obo:GO_2000242 .
obo:PHIPO_0000989 a rdfs:Class ;
rdfs:label "decreased level of pathogen protein within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen protein usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001197 .
obo:GO_0014819 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle contraction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle contraction." ;
rdfs:subClassOf obo:GO_0006942 , obo:GO_0065007 .
obo:PHIPO_0000677 a rdfs:Class ;
rdfs:label "resistance to ceftriaxone"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ceftriaxone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0000369 a rdfs:Class ;
rdfs:label "corpus striatum" ;
rdfs:comment "The corpus striatum (striated body) is a compound structure consisting of the caudate nucleus and the lentiform nucleus, which consists of the putamen and the globus pallidus[WP]." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_0099541 a rdfs:Class ;
rdfs:label "trans-synaptic signaling by lipid" ;
rdfs:comment "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid." ;
rdfs:subClassOf obo:GO_0099537 .
obo:RO_0002608 a rdf:Property ;
rdfs:label "process has causal agent" ;
rdfs:comment "Inverse of 'causal agent in process'" ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:GO_0098704 a rdfs:Class ;
rdfs:label "carbohydrate import across plasma membrane" ;
rdfs:comment "The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0034219 , obo:GO_0098739 .
obo:GO_1903780 a rdfs:Class ;
rdfs:label "negative regulation of cardiac conduction" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0065007 , obo:GO_1903779 .
obo:CHEBI_33405 a rdfs:Class ;
rdfs:label "hydracid" ;
rdfs:comment "A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ;
rdfs:subClassOf obo:CHEBI_33608 .
obo:GO_1903078 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to plasma membrane" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903076 , obo:GO_1904377 , obo:GO_1905477 .
obo:GO_0008610 a rdfs:Class ;
rdfs:label "lipid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." ;
rdfs:subClassOf obo:GO_0006629 , obo:GO_0009058 .
obo:GO_0071621 a rdfs:Class ;
rdfs:label "granulocyte chemotaxis" ;
rdfs:comment "The movement of a granulocyte in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0030595 , obo:GO_0097530 .
obo:UBERON_0000484 a rdfs:Class ;
rdfs:label "simple cuboidal epithelium" ;
rdfs:comment "Unilaminar epithelium that consists of a single layer of cuboidal cells." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0010077 .
obo:UBERON_0006815 a rdfs:Class ;
rdfs:label "areolar connective tissue" ;
rdfs:comment "Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand." ;
rdfs:subClassOf obo:UBERON_0011825 .
a rdf:Property ;
rdfs:label "protects" ;
rdfs:range .
obo:CHEBI_8984 a rdfs:Class ;
rdfs:label "sodium dodecyl sulfate" ;
rdfs:comment "An organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate." ;
rdfs:subClassOf obo:CHEBI_26819 , obo:CHEBI_38700 .
obo:GO_0098712 a rdfs:Class ;
rdfs:label "L-glutamate import across plasma membrane" ;
rdfs:comment "The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015813 , obo:GO_0089718 .
obo:GO_0034105 a rdfs:Class ;
rdfs:label "positive regulation of tissue remodeling" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of tissue remodeling." ;
rdfs:subClassOf obo:GO_0034103 , obo:GO_0051240 , obo:GO_0065007 .
obo:PHIPO_0001295 a rdfs:Class ;
rdfs:label "inhibition of pathogen polygalacturonase by host decreased"@en ;
rdfs:comment """A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen polygalacturonase
occurs to a lesser extent than normal.""" ;
rdfs:subClassOf obo:PHIPO_0000347 .
obo:PR_000011241 a rdfs:Class ;
rdfs:label "homeobox protein Nkx-2.1" ;
rdfs:comment "A protein that is a translation product of the human NKX2-1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0018958 a rdfs:Class ;
rdfs:label "phenol-containing compound metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0110125 a rdfs:Class ;
rdfs:label "negative regulation of myotube cell migration" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration." ;
rdfs:subClassOf obo:GO_0030336 , obo:GO_0065007 , obo:GO_0110123 .
obo:CHEBI_46634 a rdfs:Class ;
rdfs:label "carbapenemcarboxylic acid" ;
rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_46633 .
obo:NCBITaxon_6072 a rdfs:Class ;
rdfs:label "Eumetazoa" ;
rdfs:subClassOf obo:NCBITaxon_33208 .
obo:PHIPO_0001032 a rdfs:Class ;
rdfs:label "decreased level of pyocyanin"@en ;
rdfs:comment "A single species cell phenotype in which the amount of pyocyanin measured in a cell is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001031 .
obo:GO_1905166 a rdfs:Class ;
rdfs:label "negative regulation of lysosomal protein catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904351 , obo:GO_1905165 .
obo:CHEBI_35623 a rdfs:Class ;
rdfs:label "anticonvulsant" ;
rdfs:comment "A drug used to prevent seizures or reduce their severity." ;
rdfs:subClassOf obo:CHEBI_35488 .
obo:UBERON_0002616 a rdfs:Class ;
rdfs:label "regional part of brain" ;
rdfs:comment "Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia." ;
rdfs:subClassOf obo:UBERON_0000073 , obo:UBERON_0000481 .
obo:UBERON_0000966 a rdfs:Class ;
rdfs:label "retina" ;
rdfs:comment "The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0005388 .
obo:UBERON_0004548 a rdfs:Class ;
rdfs:label "left eye" ;
rdfs:comment "An eye that is part of a left side of organism [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000970 , obo:UBERON_0015212 .
obo:BSPO_0000120 a rdf:Property ;
rdfs:range .
obo:CHEBI_33457 a rdfs:Class ;
rdfs:label "phosphorus oxoacid" ;
rdfs:comment "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." ;
rdfs:subClassOf obo:CHEBI_33408 , obo:CHEBI_36360 .
obo:GO_0099173 a rdfs:Class ;
rdfs:label "postsynapse organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0016043 .
obo:PHIPO_0000004 a rdfs:Class ;
rdfs:label "unaffected pathogenicity" ;
rdfs:comment "A phenotype where the ability of a pathogen, to produce an infectious disease in another organism is unaffected (i.e the same as wild-type, it could be pathogenic or non-pathogenic)." ;
rdfs:subClassOf obo:PHIPO_0000006 .
obo:GO_1904770 a rdfs:Class ;
rdfs:label "intramembranous bone morphogenesis" ;
rdfs:comment "The developmental process by which an intramembranous bone is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060349 .
obo:GO_1904411 a rdfs:Class ;
rdfs:label "positive regulation of secretory granule organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of secretory granule organization." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0065007 , obo:GO_1904409 .
obo:CHEBI_22728 a rdfs:Class ;
rdfs:label "benzopyrrole" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 , obo:CHEBI_38180 .
obo:UBERON_0011864 a rdfs:Class ;
rdfs:label "tendon collagen fibril" ;
rdfs:comment "The connective tissue bundles in the extracellular matrix of tendon tissue that are composed of collagen, and play a role in tissue strength and elasticity." ;
rdfs:subClassOf obo:UBERON_0011860 .
obo:GO_0061536 a rdfs:Class ;
rdfs:label "glycine secretion" ;
rdfs:comment "The controlled release of glycine by a cell." ;
rdfs:subClassOf obo:GO_0015816 , obo:GO_0032940 , obo:GO_0046903 .
obo:CHEBI_25693 a rdfs:Class ;
rdfs:label "organic heteromonocyclic compound" ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33670 .
obo:GO_0099054 a rdfs:Class ;
rdfs:label "presynapse assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a presynapse." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0022607 , obo:GO_0099172 .
a rdfs:Class ;
rdfs:label "ventricular systems" ;
rdfs:subClassOf , obo:UBERON_0005281 .
obo:GO_0005515 a rdfs:Class ;
rdfs:label "protein binding" ;
rdfs:comment "Binding to a protein." ;
rdfs:subClassOf obo:GO_0005488 .
obo:CHEBI_84735 a rdfs:Class ;
rdfs:label "algal metabolite" ;
rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." ;
rdfs:subClassOf obo:CHEBI_75763 .
obo:CHEBI_17137 a rdfs:Class ;
rdfs:label "hydrogensulfite" ;
rdfs:subClassOf obo:CHEBI_33482 .
obo:CL_0000154 a rdfs:Class ;
rdfs:label "protein secreting cell" ;
rdfs:comment "Any secretory cell that is capable of some protein secretion." ;
rdfs:subClassOf obo:CL_0000151 .
obo:PHIPO_0001138 a rdfs:Class ;
rdfs:label "decreased number of asexual reproductive structures"@en ;
rdfs:comment "A single species phenotype where the frequency of occurrence of asexual reproductive structures is decreased." ;
rdfs:subClassOf obo:PHIPO_0000121 .
obo:CHEBI_61800 a rdfs:Class ;
rdfs:label "2-deoxystreptamine derivative" ;
rdfs:comment "Any derivative of 2-deoxystreptamine." ;
rdfs:subClassOf obo:CHEBI_61689 .
obo:GO_0048505 a rdfs:Class ;
rdfs:label "regulation of timing of cell differentiation" ;
rdfs:comment "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development." ;
rdfs:subClassOf obo:GO_0040034 , obo:GO_0045595 .
obo:UBERON_0005288 a rdfs:Class ;
rdfs:label "tela choroidea of third ventricle" ;
rdfs:comment "Tela chorioidea that lines the third ventricle[ZFA]. The part of the choroid plexus in relation to the body of the ventricle forms the vascular fringed margin of a triangular process of pia mater, named the tela chorioidea of the third ventricle, and projects from under cover of the lateral edge of the fornix. Blood is supplied by branches from the superior cerebellar artery[WP]." ;
rdfs:subClassOf obo:UBERON_0005283 .
obo:PHIPO_0001219 a rdfs:Class ;
rdfs:label "normal growth on voriconazole"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to voriconazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CL_0000080 a rdfs:Class ;
rdfs:label "circulating cell" ;
rdfs:comment "A cell which moves among different tissues of the body, via blood, lymph, or other medium." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_1990751 a rdfs:Class ;
rdfs:label "Schwann cell chemotaxis" ;
rdfs:comment "The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0036135 , obo:GO_0060326 .
obo:CHEBI_58942 a rdfs:Class ;
rdfs:label "cationic amino-acid residue" ;
rdfs:comment "An amino-acid residue protonated on nitrogen." ;
rdfs:subClassOf obo:CHEBI_64769 .
obo:CL_0000126 a rdfs:Class ;
rdfs:label "macroglial cell" ;
rdfs:comment "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together." ;
rdfs:subClassOf obo:CL_0000125 .
obo:GO_0007517 a rdfs:Class ;
rdfs:label "muscle organ development" ;
rdfs:comment "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 , obo:GO_0061061 .
obo:UBERON_0004461 a rdfs:Class ;
rdfs:label "skeletal musculature of head" ;
rdfs:comment "Any collection of skeletal muscles that is part of a head [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001015 , obo:UBERON_0008229 .
obo:RO_0002371 a rdf:Property ;
rdfs:label "attached to"@en ;
rdfs:comment "a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a" ;
rdfs:domain obo:UBERON_0000061 ;
rdfs:range obo:UBERON_0000061 ;
rdfs:subPropertyOf obo:RO_0002177 , obo:RO_0002170 .
obo:UBERON_0018150 a rdfs:Class ;
rdfs:label "skin of lower lip" ;
rdfs:comment "A zone of skin that is part of a lower lip." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0001458 .
obo:CL_4310095 a rdfs:Class ;
rdfs:label "GPi Core internal globus pallidus core projecting neuron (Primate)" ;
rdfs:comment "A internal globus pallidus core projecting neuron of the Primates brain. These cells are located in the internal segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPi Core." ;
rdfs:subClassOf obo:CL_0020003 .
obo:NCBITaxon_862507 a rdfs:Class ;
rdfs:label "Mus " ;
rdfs:subClassOf obo:NCBITaxon_10088 .
obo:GO_0098528 a rdfs:Class ;
rdfs:label "skeletal muscle fiber differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract." ;
rdfs:subClassOf obo:GO_0014902 , obo:GO_0030154 , obo:GO_0035914 .
obo:CL_4023058 a rdfs:Class ;
rdfs:label "mesothelial fibroblast of the leptomeninx" ;
rdfs:comment "A mesothelial fibroblast found in the leptomeninx." ;
rdfs:subClassOf obo:CL_0002319 , obo:CL_4023054 .
obo:PHIPO_0000317 a rdfs:Class ;
rdfs:label "obsolete increased effector of virulence activation of host defense" ;
rdfs:comment "The pathogen effector entity has an increased ability to activate host defense." .
obo:GO_0003298 a rdfs:Class ;
rdfs:label "physiological muscle hypertrophy" ;
rdfs:comment "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development." ;
rdfs:subClassOf obo:GO_0014896 .
obo:UBERON_0003848 a rdfs:Class ;
rdfs:label "gonadal vein" ;
rdfs:comment "In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:PHIPO_0000727 a rdfs:Class ;
rdfs:label "sensitive to clofazimine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to clofazimine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0060563 a rdfs:Class ;
rdfs:label "neuroepithelial cell differentiation" ;
rdfs:comment "The process in which epiblast cells acquire specialized features of neuroepithelial cells." ;
rdfs:subClassOf obo:GO_0002065 , obo:GO_0030154 .
obo:UBERON_0019206 a rdfs:Class ;
rdfs:label "tongue papilla epithelium" ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0002424 , obo:UBERON_0003357 .
obo:UBERON_0004140 a rdfs:Class ;
rdfs:label "primary heart field" ;
rdfs:comment "A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005291 , obo:UBERON_0007688 .
obo:UBERON_0003471 a rdfs:Class ;
rdfs:label "artery of lower lip" ;
rdfs:comment "The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0003496 , obo:UBERON_0009657 .
obo:RO_0002252 a rdf:Property ;
rdfs:label "connecting branch of" ;
rdfs:comment "b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002375 , obo:RO_0002170 .
obo:UBERON_0003498 a rdfs:Class ;
rdfs:label "heart blood vessel" ;
rdfs:comment "A blood vessel that is part of a heart [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003834 , obo:UBERON_0005985 .
obo:PHIPO_0001276 a rdfs:Class ;
rdfs:label "increased number of host galls during pathogen invasion"@en ;
rdfs:comment "A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in an increased number of plant galls (BTO:0005833 plant gall)." ;
rdfs:subClassOf obo:PHIPO_0001268 .
obo:GO_0002262 a rdfs:Class ;
rdfs:label "myeloid cell homeostasis" ;
rdfs:comment "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0048872 .
obo:GO_0070586 a rdfs:Class ;
rdfs:label "cell-cell adhesion involved in gastrulation" ;
rdfs:comment "The attachment of one cell to another cell affecting gastrulation." ;
rdfs:subClassOf obo:GO_0098609 .
obo:CL_4023069 a rdfs:Class ;
rdfs:label "medial ganglionic eminence derived GABAergic interneuron" ;
rdfs:comment "A GABAergic interneuron that develops from the medial ganglionic eminence and has migrated to the cerebral cortex." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_0010011 , obo:CL_4023063 .
obo:GO_0045806 a rdfs:Class ;
rdfs:label "negative regulation of endocytosis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis." ;
rdfs:subClassOf obo:GO_0030100 , obo:GO_0051051 , obo:GO_0051129 , obo:GO_0065007 .
obo:CHEBI_53339 a rdfs:Class ;
rdfs:label "olefinic fatty acid" ;
rdfs:comment "Any fatty acid containing at least one C=C double bond." ;
rdfs:subClassOf obo:CHEBI_27208 , obo:CHEBI_78840 .
obo:GO_0036336 a rdfs:Class ;
rdfs:label "dendritic cell migration" ;
rdfs:comment "The movement of a dendritic cell within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0071674 .
obo:PATO_0045086 a rdfs:Class ;
rdfs:label "normal occurrence" ;
rdfs:comment "An occurrence which is relatively normal." ;
rdfs:subClassOf obo:PATO_0000057 , obo:PATO_0045073 .
obo:RO_0015010 a rdf:Property ;
rdfs:label "has relative magnitude" ;
rdfs:range .
obo:UBERON_0002362 a rdfs:Class ;
rdfs:label "arachnoid mater" ;
rdfs:comment "A think avascular meningeal layer, between the pia mater and the dural mater. It is separated from the pia mater by the subarachnoid space." ;
rdfs:subClassOf obo:UBERON_0000391 .
obo:CHEBI_76697 a rdfs:Class ;
rdfs:label "EC 5.99.* (other isomerases) inhibitor" ;
rdfs:comment "An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*)." ;
rdfs:subClassOf obo:CHEBI_75596 .
obo:CL_1000428 a rdfs:Class ;
rdfs:label "stem cell of epidermis" ;
rdfs:comment "A somatic stem cell that is part of the epidermis." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000723 .
obo:UBERON_0015833 a rdfs:Class ;
rdfs:label "foregut epithelium" ;
rdfs:comment "An epithelium that is part of a foregut." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003929 .
obo:GO_1904754 a rdfs:Class ;
rdfs:label "positive regulation of vascular associated smooth muscle cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration." ;
rdfs:subClassOf obo:GO_0014911 , obo:GO_0065007 , obo:GO_1904752 .
obo:UBERON_0009133 a rdfs:Class ;
rdfs:label "pleuroperitoneal membrane" ;
rdfs:comment "A fold of tissue which extends into the peritoneal cavity of the developing embryo and participates in the separation of the pleural and peritoneal cavities." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005291 .
obo:PHIPO_0001247 a rdfs:Class ;
rdfs:label "pathogen modulation of host metabolic process phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which a pathogen effects a change in the metabolic processes of its host organism." ;
rdfs:subClassOf obo:PHIPO_0001173 .
obo:UBERON_0016570 a rdfs:Class ;
rdfs:label "lamina of gray matter of spinal cord" ;
rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0022303 .
obo:CL_4301612 a rdfs:Class ;
rdfs:label "newly formed oligodendrocyte (Mmus)" ;
rdfs:comment "A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Ptprb (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1182 NFOL NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4072001 , obo:CL_4300367 .
obo:UBERON_0001612 a rdfs:Class ;
rdfs:label "facial artery" ;
rdfs:comment "A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0035398 .
obo:UBERON_0007214 a rdfs:Class ;
rdfs:label "mesenchyme derived from trunk neural crest" ;
rdfs:comment "Mesenchyme that develops_from a trunk neural crest." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005256 .
obo:GO_1900120 a rdfs:Class ;
rdfs:label "regulation of receptor binding" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor." ;
rdfs:subClassOf obo:GO_0043393 , obo:GO_0065007 .
obo:PHIPO_0001043 a rdfs:Class ;
rdfs:label "level of pathogen produced toxin within host phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, which affects the level of pathogen produced toxin during host infection." ;
rdfs:subClassOf obo:PHIPO_0001197 .
obo:PHIPO_0000855 a rdfs:Class ;
rdfs:label "sensitive to doxycycline"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to doxycycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0010820 a rdfs:Class ;
rdfs:label "positive regulation of T cell chemotaxis" ;
rdfs:comment "Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0010819 , obo:GO_0065007 , obo:GO_0140131 , obo:GO_2000406 .
obo:UBERON_0014387 a rdfs:Class ;
rdfs:label "mesenchyme derived from neural crest" ;
rdfs:comment "Mesenchyme that develops_from the neural crest[Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0010313 .
obo:CHEBI_48923 a rdfs:Class ;
rdfs:label "erythromycin" ;
rdfs:comment "Any of several wide-spectrum macrolide antibiotics obtained from actinomycete Saccharopolyspora erythraea (formerly known as Streptomyces erythraeus)." ;
rdfs:subClassOf obo:CHEBI_23953 .
a rdfs:Class ;
rdfs:label "Superior salivatory nucleus" ;
rdfs:subClassOf , obo:UBERON_0002149 .
obo:GO_1903904 a rdfs:Class ;
rdfs:label "negative regulation of establishment of T cell polarity" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity." ;
rdfs:subClassOf obo:GO_0050868 , obo:GO_0065007 , obo:GO_1903903 .
a rdfs:Class ;
rdfs:label "third ventricle" ;
rdfs:subClassOf , obo:UBERON_0002286 .
obo:UBERON_0001994 a rdfs:Class ;
rdfs:label "hyaline cartilage tissue" ;
rdfs:comment "Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance." ;
rdfs:subClassOf obo:UBERON_0002418 .
obo:GO_0009952 a rdfs:Class ;
rdfs:label "anterior/posterior pattern specification" ;
rdfs:comment "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." ;
rdfs:subClassOf obo:GO_0003002 .
obo:GO_0141187 a rdfs:Class ;
rdfs:label "nucleic acid biosynthetic process" ;
rdfs:comment "The biosynthetic process resulting in the formation of a nucleic acid." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0009059 , obo:GO_0034654 , obo:GO_0090304 .
obo:CHEBI_133598 a rdfs:Class ;
rdfs:label "chlortetracycline(1-)" ;
rdfs:comment "An organic anion that is the major structure of chlortetracycline at pH 7.3 (according to Marvin v 6.2.0.)." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:GO_0050680 a rdfs:Class ;
rdfs:label "negative regulation of epithelial cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0050678 , obo:GO_0065007 .
obo:GO_0070727 a rdfs:Class ;
rdfs:label "cellular macromolecule localization" ;
rdfs:comment "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." ;
rdfs:subClassOf obo:GO_0033036 , obo:GO_0051641 .
obo:GO_0006338 a rdfs:Class ;
rdfs:label "chromatin remodeling" ;
rdfs:comment "A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication." ;
rdfs:subClassOf obo:GO_0006325 .
obo:UBERON_0004643 a rdfs:Class ;
rdfs:label "lateral ventricle ependyma" ;
rdfs:comment "An ependyma that is part of a lateral ventricle [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0004670 , obo:UBERON_0005357 .
obo:CHEBI_64271 a rdfs:Class ;
rdfs:label "tunicamycin D1" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a heptadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:CHEBI_27666 a rdfs:Class ;
rdfs:label "actinomycin D" ;
rdfs:subClassOf obo:CHEBI_15369 , obo:CHEBI_35213 .
obo:RO_0018036 a rdf:Property ;
rdfs:range .
a rdf:Property ;
rdfs:range .
obo:GO_0010968 a rdfs:Class ;
rdfs:label "regulation of microtubule nucleation" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." ;
rdfs:subClassOf obo:GO_0031113 , obo:GO_0065007 .
obo:PATO_0000407 a rdfs:Class ;
rdfs:label "flat" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's having a horizontal surface without a slope, tilt, or curvature." ;
rdfs:subClassOf obo:PATO_0002254 .
obo:CHEBI_76967 a rdfs:Class ;
rdfs:label "human xenobiotic metabolite" ;
rdfs:comment "Any human metabolite produced by metabolism of a xenobiotic compound in humans." ;
rdfs:subClassOf obo:CHEBI_76206 , obo:CHEBI_77746 .
obo:CHEBI_35674 a rdfs:Class ;
rdfs:label "antihypertensive agent" ;
rdfs:comment "Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism." ;
rdfs:subClassOf obo:CHEBI_35554 .
obo:GO_0030103 a rdfs:Class ;
rdfs:label "vasopressin secretion" ;
rdfs:comment "The regulated release of vasopressin from secretory granules into the blood." ;
rdfs:subClassOf obo:GO_0030072 , obo:GO_0046903 .
obo:GO_0061301 a rdfs:Class ;
rdfs:label "cerebellum vasculature morphogenesis" ;
rdfs:comment "The process in which the vasculature of the cerebellum is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:UBERON_0004175 a rdfs:Class ;
rdfs:label "internal genitalia" ;
rdfs:comment "The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." ;
rdfs:subClassOf obo:UBERON_0003133 .
obo:GO_0005581 a rdfs:Class ;
rdfs:label "collagen trimer" ;
rdfs:comment "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." ;
rdfs:subClassOf obo:GO_0032991 .
obo:UBERON_0001605 a rdfs:Class ;
rdfs:label "ciliary muscle" ;
rdfs:comment "The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0003386 , obo:UBERON_0010314 , obo:UBERON_0011222 .
obo:CHEBI_79020 a rdfs:Class ;
rdfs:label "alpha,beta-unsaturated monocarboxylic acid" ;
rdfs:comment "A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C≡C bond." ;
rdfs:subClassOf obo:CHEBI_25384 .
obo:GO_0045904 a rdfs:Class ;
rdfs:label "negative regulation of translational termination" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination." ;
rdfs:subClassOf obo:GO_0006449 , obo:GO_0017148 , obo:GO_0043242 , obo:GO_0065007 .
obo:CHEBI_83753 a rdfs:Class ;
rdfs:label "(2R,3R)-cyproconazole" ;
rdfs:comment "The (2R,3R)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol." ;
rdfs:subClassOf obo:CHEBI_83748 .
obo:GO_1905517 a rdfs:Class ;
rdfs:label "macrophage migration" ;
rdfs:comment "The orderly movement of a macrophage from one site to another." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0071674 , obo:GO_0097529 .
obo:GO_0098802 a rdfs:Class ;
rdfs:label "plasma membrane signaling receptor complex" ;
rdfs:comment "Any protein complex that is part of the plasma membrane and which functions as a signaling receptor." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0043235 , obo:GO_0098797 .
obo:CHEBI_38443 a rdfs:Class ;
rdfs:label "1-benzopyran" ;
rdfs:subClassOf obo:CHEBI_22727 .
obo:GO_0043392 a rdfs:Class ;
rdfs:label "negative regulation of DNA binding" ;
rdfs:comment "Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)." ;
rdfs:subClassOf obo:GO_0051100 , obo:GO_0051101 , obo:GO_0065007 .
obo:SO_0000704 a rdfs:Class .
obo:CHEBI_72695 a rdfs:Class ;
rdfs:label "organic molecule" ;
rdfs:comment "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." ;
rdfs:subClassOf obo:CHEBI_25367 , obo:CHEBI_50860 .
obo:PHIPO_0000159 a rdfs:Class ;
rdfs:label "normal subcellular component"@en ;
rdfs:comment "A single species phenotype in which the amount, distribution, composition or morphology of a cell part is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000463 .
obo:CHEBI_18407 a rdfs:Class ;
rdfs:label "hydrogen cyanide" ;
rdfs:comment "A one-carbon compound consisting of a methine group triple bonded to a nitrogen atom" ;
rdfs:subClassOf obo:CHEBI_33405 , obo:CHEBI_64708 .
obo:UBERON_0007499 a rdfs:Class ;
rdfs:label "epithelial sac" ;
rdfs:comment "An epithelial tube that is open at one end only." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003914 , obo:UBERON_0009856 .
obo:UBERON_0011997 a rdfs:Class ;
rdfs:label "coelom" ;
rdfs:comment "The aggregate of the coelemic cavity lumen plus the membranes that line the lumen." ;
rdfs:subClassOf obo:UBERON_0000481 .
obo:UBERON_0001474 a rdfs:Class ;
rdfs:label "bone element" ;
rdfs:comment "Skeletal element that is composed of bone tissue." ;
rdfs:subClassOf obo:UBERON_0004765 .
obo:GO_0048285 a rdfs:Class ;
rdfs:label "organelle fission" ;
rdfs:comment "The creation of two or more organelles by division of one organelle." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0009987 .
obo:GOREL_0002004 a rdf:Property ;
rdfs:label "results in fission of" ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0000057 .
obo:GO_0042110 a rdfs:Class ;
rdfs:label "T cell activation" ;
rdfs:comment "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0046649 .
obo:CHEBI_33848 a rdfs:Class ;
rdfs:label "polycyclic arene" ;
rdfs:comment "A polycyclic aromatic hydrocarbon." ;
rdfs:subClassOf obo:CHEBI_33658 , obo:CHEBI_33666 .
obo:CL_0000075 a rdfs:Class ;
rdfs:label "columnar/cuboidal epithelial cell" ;
rdfs:comment "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ;
rdfs:subClassOf obo:CL_0000066 .
obo:GO_0019786 a rdfs:Class ;
rdfs:label "protein-phosphatidylethanolamide deconjugating activity" ;
rdfs:comment "Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue." ;
rdfs:subClassOf obo:GO_0016787 , obo:GO_0140096 .
obo:GO_0007010 a rdfs:Class ;
rdfs:label "cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0016043 .
obo:UBERON_0034715 a rdfs:Class ;
rdfs:label "pineal tract" ;
rdfs:comment "A cranial nerve fiber tract that innervates the pineal body." ;
rdfs:subClassOf obo:UBERON_0034713 , obo:UBERON_0034714 .
obo:RO_0002380 a rdf:Property ;
rdfs:label "branching part of"@en ;
rdfs:comment "x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002375 , obo:BFO_0000050 .
obo:PR_000040662 a rdfs:Class ;
rdfs:label "cathepsin-like protease" ;
rdfs:comment "A protein that is a translation product of some metazoan gene that encodes a signal peptide followed by a single Cathepsin propeptide inhibitor domain (Pfam:PF08246) followed by a single Papain family cysteine protease (Pfam:PF00112) domain at the C terminus." ;
rdfs:subClassOf obo:PR_000036194 .
obo:UBERON_0034720 a rdfs:Class ;
rdfs:label "head taste bud" ;
rdfs:comment "A taste bud that is located on the skin of the head." ;
rdfs:subClassOf obo:UBERON_0001727 , obo:UBERON_0034717 .
obo:GO_0001816 a rdfs:Class ;
rdfs:label "cytokine production" ;
rdfs:comment "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0010467 , obo:GO_0032501 .
obo:GO_0022411 a rdfs:Class ;
rdfs:label "cellular component disassembly" ;
rdfs:comment "A cellular process that results in the breakdown of a cellular component." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0016043 .
obo:RO_0002590 a rdf:Property ;
rdfs:label "results in disassembly of" ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002592 , obo:RO_0002586 .
obo:GO_0006941 a rdfs:Class ;
rdfs:label "striated muscle contraction" ;
rdfs:comment "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope." ;
rdfs:subClassOf obo:GO_0006936 .
obo:UBERON_0003568 a rdfs:Class ;
rdfs:label "neck connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a neck [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:GO_0050768 a rdfs:Class ;
rdfs:label "negative regulation of neurogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0050767 , obo:GO_0051961 , obo:GO_0065007 .
obo:GO_1905557 a rdfs:Class ;
rdfs:label "regulation of mitotic nuclear envelope disassembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly." ;
rdfs:subClassOf obo:GO_0010549 , obo:GO_0010564 , obo:GO_0065007 .
obo:GO_0045662 a rdfs:Class ;
rdfs:label "negative regulation of myoblast differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0045661 , obo:GO_0065007 .
obo:GO_0160307 a rdfs:Class ;
rdfs:label "protein biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of protein." ;
rdfs:subClassOf obo:GO_0006412 , obo:GO_0009059 .
obo:RO_0002230 a rdf:Property ;
rdfs:label "ends with"@en ;
rdfs:comment "x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000051 .
obo:PATO_0040003 a rdfs:Class ;
rdfs:label "pathogenicity" ;
rdfs:comment "The ability of a pathogen to produce an infectious disease or disorder in an another organism." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:PHIPO_0000113 a rdfs:Class ;
rdfs:label "obsolete altered functionality of penetration structure" ;
rdfs:comment "Penetration structure formed but not functioning in the same manner as the wild type." .
obo:UBERON_0001805 a rdfs:Class ;
rdfs:label "autonomic ganglion" ;
rdfs:comment "Ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion." ;
rdfs:subClassOf obo:UBERON_0000045 , obo:UBERON_0003338 .
obo:UBERON_0003292 a rdfs:Class ;
rdfs:label "meninx of spinal cord" ;
rdfs:comment "A meninx that is part of a spinal cord [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002360 , obo:UBERON_0005174 .
obo:UBERON_0000166 a rdfs:Class ;
rdfs:label "oral opening" ;
rdfs:comment "The orifice that connects the mouth to the exterior of the body." ;
rdfs:subClassOf obo:UBERON_0000161 .
obo:GO_0022604 a rdfs:Class ;
rdfs:label "regulation of cell morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0065007 .
obo:UBERON_0003614 a rdfs:Class ;
rdfs:label "blood vessel elastic tissue" ;
rdfs:comment "Elastic tissue layer that lines a blood vessel layer." ;
rdfs:subClassOf obo:UBERON_0002521 , obo:UBERON_0003613 .
obo:CHEBI_30212 a rdfs:Class .
obo:UBERON_0002384 a rdfs:Class ;
rdfs:label "connective tissue" ;
rdfs:comment "Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:GO_0003169 a rdfs:Class ;
rdfs:label "coronary vein morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of veins of the heart are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048845 , obo:GO_0060977 .
obo:GO_0003342 a rdfs:Class ;
rdfs:label "proepicardium development" ;
rdfs:comment "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060485 .
obo:UBERON_0006846 a rdfs:Class ;
rdfs:label "surface groove" ;
rdfs:comment "A furrow or an incomplete tube." ;
rdfs:subClassOf obo:UBERON_0000466 .
obo:RO_0002572 a rdf:Property ;
rdfs:label "luminal space of" ;
rdfs:comment "s is luminal space of x iff s is lumen_of x and s is an immaterial entity" ;
rdfs:domain obo:BFO_0000141 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002571 .
obo:CHEBI_62220 a rdfs:Class ;
rdfs:label "pyocyanine(1+)" ;
rdfs:comment "An organic cation resulting from the protonation of pyocyanin." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_39201 .
obo:CHEBI_16040 a rdfs:Class ;
rdfs:label "cytosine" ;
rdfs:comment "An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4." ;
rdfs:subClassOf obo:CHEBI_26432 , obo:CHEBI_38337 , obo:CHEBI_38338 , obo:CHEBI_38387 .
obo:UBERON_0004345 a rdfs:Class ;
rdfs:label "trophectoderm" ;
rdfs:comment "Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0005292 .
obo:GO_1901694 a rdfs:Class ;
rdfs:label "positive regulation of compound eye retinal cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0046672 , obo:GO_0065007 , obo:GO_1901692 .
obo:CHEBI_35568 a rdfs:Class ;
rdfs:label "mancude ring" ;
rdfs:comment "Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:NCBITaxon_10088 a rdfs:Class ;
rdfs:label "Mus " ;
rdfs:subClassOf obo:NCBITaxon_39107 .
obo:CHEBI_26562 a rdfs:Class ;
rdfs:label "ribose phosphate" ;
rdfs:subClassOf obo:CHEBI_25900 .
obo:PHIPO_0000967 a rdfs:Class ;
rdfs:label "abolished pathogen penetration across the barrier"@en ;
rdfs:comment "A single species pathogen penetration phenotype in in which the ability of the pathogen to penetrate a given experimental substance/membrane is abolished." ;
rdfs:subClassOf obo:PHIPO_0000030 .
obo:GO_0048844 a rdfs:Class ;
rdfs:label "artery morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048514 .
obo:GO_0043170 a rdfs:Class ;
rdfs:label "macromolecule metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0008152 .
obo:PHIPO_0000716 a rdfs:Class ;
rdfs:label "sensitive to cefixime"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefixime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_2000176 a rdfs:Class ;
rdfs:label "positive regulation of pro-T cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation." ;
rdfs:subClassOf obo:GO_0045582 , obo:GO_0065007 , obo:GO_1905458 , obo:GO_2000174 .
obo:UBERON_0001883 a rdfs:Class ;
rdfs:label "olfactory tubercle" ;
rdfs:comment "Region in the ventral telencephalon, prominent in rodents, but present in all mammals, consisting of a laminated cortical part and the cap/hilus region. It is traditionally viewed as part of the olfactory cortex but recognized by some as having a striatal character. According to many authors, the structure of the OT transitions from cortical like to striatal like along the lateral medial axis. (Maryann Martone)." ;
rdfs:subClassOf obo:UBERON_0009663 .
obo:GO_0060136 a rdfs:Class ;
rdfs:label "embryonic process involved in female pregnancy" ;
rdfs:comment "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother." ;
rdfs:subClassOf obo:GO_0022414 , obo:GO_0048609 .
obo:CHEBI_84291 a rdfs:Class ;
rdfs:label "organic sulfur anion" ;
rdfs:comment "An organic anion in which the charge resides on a sulfur atom." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_26835 .
obo:CHEBI_51867 a rdfs:Class ;
rdfs:label "methyl ketone" ;
rdfs:comment "A ketone of formula RC(=O)CH3 (R ≠ H)." ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:CL_0000100 a rdfs:Class ;
rdfs:label "motor neuron" ;
rdfs:comment "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." ;
rdfs:subClassOf obo:CL_0000527 .
obo:PATO_0001550 a rdfs:Class ;
rdfs:label "decreased sensitivity toward" ;
rdfs:comment "A sensitivity toward an external stimulus which is lower than normal/average." ;
rdfs:subClassOf obo:PATO_0000516 , obo:PATO_0002303 .
obo:CHEBI_48819 a rdfs:Class ;
rdfs:label "cyano group" ;
rdfs:subClassOf obo:CHEBI_36823 .
obo:RO_0018037 a rdf:Property ;
rdfs:range .
obo:GO_0022008 a rdfs:Class ;
rdfs:label "neurogenesis" ;
rdfs:comment "Generation of cells within the nervous system." ;
rdfs:subClassOf obo:GO_0030154 .
obo:CHEBI_6472 a rdfs:Class ;
rdfs:label "lincomycin" ;
rdfs:comment "A carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis." ;
rdfs:subClassOf obo:CHEBI_23007 , obo:CHEBI_35275 , obo:CHEBI_46770 , obo:CHEBI_84186 .
obo:GO_0098544 a rdfs:Class ;
rdfs:label "maintenance of protein complex location" ;
rdfs:comment "Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away." ;
rdfs:subClassOf obo:GO_0031503 , obo:GO_0051235 .
obo:GO_0060012 a rdfs:Class ;
rdfs:label "synaptic transmission, glycinergic" ;
rdfs:comment "The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ;
rdfs:subClassOf obo:GO_0007268 .
obo:CL_0002372 a rdfs:Class ;
rdfs:label "myotube" ;
rdfs:comment "A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development." ;
rdfs:subClassOf obo:CL_0000187 , obo:CL_0000737 , obo:CL_4052002 .
obo:GO_1902211 a rdfs:Class ;
rdfs:label "regulation of prolactin signaling pathway" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of prolactin signaling pathway." ;
rdfs:subClassOf obo:GO_0001959 , obo:GO_0065007 .
obo:GO_2000472 a rdfs:Class ;
rdfs:label "negative regulation of hematopoietic stem cell migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration." ;
rdfs:subClassOf obo:GO_0030336 , obo:GO_0065007 , obo:GO_2000471 .
obo:UBERON_0002418 a rdfs:Class ;
rdfs:label "cartilage tissue" ;
rdfs:comment "Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts." ;
rdfs:subClassOf obo:UBERON_0004755 .
obo:CL_0012001 a rdfs:Class ;
rdfs:label "neuron of the forebrain" ;
rdfs:comment "A CNS neuron of the forebrain." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000029 .
obo:UBERON_0014892 a rdfs:Class ;
rdfs:label "skeletal muscle organ, vertebrate" ;
rdfs:comment "A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles)." ;
rdfs:subClassOf obo:UBERON_0001630 .
obo:RO_0002103 a rdf:Property ;
rdfs:label "synapsed by"@en ;
rdfs:comment "Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. "@en ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002485 .
obo:GO_0051931 a rdfs:Class ;
rdfs:label "regulation of sensory perception" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal." ;
rdfs:subClassOf obo:GO_0031644 , obo:GO_0065007 .
obo:CHEBI_36688 a rdfs:Class ;
rdfs:label "heterotricyclic compound" ;
rdfs:subClassOf obo:CHEBI_33671 .
obo:CHEBI_60895 a rdfs:Class ;
rdfs:label "D-alpha-amino acid anion" ;
rdfs:comment "Any α-amino acid anion in which the parent amino acid has D-configuration." ;
rdfs:subClassOf obo:CHEBI_33558 .
a rdf:Property ;
rdfs:range .
obo:GO_0048628 a rdfs:Class ;
rdfs:label "myoblast maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0048469 .
obo:GO_0008320 a rdfs:Class ;
rdfs:label "transmembrane protein transporter activity" ;
rdfs:comment "Enables the transfer of a protein from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0005215 , obo:GO_0022884 , obo:GO_0140318 .
obo:CHEBI_26218 a rdfs:Class ;
rdfs:label "potassium salt" ;
rdfs:comment "Any alkali metal salt having potassium(1+) as the cation." ;
rdfs:subClassOf obo:CHEBI_26217 , obo:CHEBI_35479 .
obo:GO_0002690 a rdfs:Class ;
rdfs:label "positive regulation of leukocyte chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0002687 , obo:GO_0002688 , obo:GO_0050921 , obo:GO_0065007 .
obo:UBERON_0015129 a rdfs:Class ;
rdfs:label "epicardial fat" ;
rdfs:comment "Visceral intrapericardial fat contiguous with the myocardial surface." ;
rdfs:subClassOf obo:UBERON_0001013 , obo:UBERON_0003837 , obo:UBERON_0035814 .
obo:RO_0002221 a rdf:Property ;
rdfs:label "surrounds"@en ;
rdfs:comment "inverse of surrounded by" ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002220 .
obo:GO_0033685 a rdfs:Class ;
rdfs:label "negative regulation of luteinizing hormone secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone." ;
rdfs:subClassOf obo:GO_0032277 , obo:GO_0033684 , obo:GO_0065007 .
obo:GO_0006721 a rdfs:Class ;
rdfs:label "terpenoid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups." ;
rdfs:subClassOf obo:GO_0006720 .
obo:CHEBI_60798 a rdfs:Class ;
rdfs:label "excitatory amino acid antagonist" ;
rdfs:comment "Any substance which inhibits the action of receptors for excitatory amino acids." ;
rdfs:subClassOf obo:CHEBI_48706 .
obo:CHEBI_26395 a rdfs:Class ;
rdfs:label "purine nucleotide" ;
rdfs:comment "Any nucleotide that has a purine nucleobase." ;
rdfs:subClassOf obo:CHEBI_26401 , obo:CHEBI_36976 .
obo:PHIPO_0000189 a rdfs:Class ;
rdfs:label "obsolete altered pathogen host interaction DNA binding specificity" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which a gene product that normally binds to a specific DNA sequence instead binds to a different sequence when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:GO_0060452 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle contraction" ;
rdfs:comment "Any process that increases the frequency, rate or extent of cardiac muscle contraction." ;
rdfs:subClassOf obo:GO_0045823 , obo:GO_0045989 , obo:GO_0055117 , obo:GO_0065007 .
obo:PHIPO_0000705 a rdfs:Class ;
rdfs:label "resistance to norfloxacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to norfloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0005597 a rdfs:Class ;
rdfs:label "lung primordium" ;
rdfs:comment "A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum." ;
rdfs:subClassOf obo:UBERON_0001048 .
obo:CHEBI_46847 a rdfs:Class ;
rdfs:label "N-iminopiperazine" ;
rdfs:subClassOf obo:CHEBI_26144 .
obo:PHIPO_0001195 a rdfs:Class ;
rdfs:label "inhibition of pathogen chorismate mutase by host present"@en ;
rdfs:comment "A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen chorismate mutase is present." ;
rdfs:subClassOf obo:PHIPO_0000347 .
obo:GO_0048661 a rdfs:Class ;
rdfs:label "positive regulation of smooth muscle cell proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0048660 , obo:GO_0065007 .
obo:GO_0032870 a rdfs:Class ;
rdfs:label "cellular response to hormone stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." ;
rdfs:subClassOf obo:GO_0009725 , obo:GO_0070887 , obo:GO_0071495 .
obo:GO_0090515 a rdfs:Class ;
rdfs:label "L-glutamate transmembrane import into vacuole" ;
rdfs:comment "The directed movement of L-glutamate into the vacuole across the vacuolar membrane." ;
rdfs:subClassOf obo:GO_0015800 , obo:GO_0015813 , obo:GO_0090454 .
obo:PHIPO_0000400 a rdfs:Class ;
rdfs:label "abnormal cellular component organization"@en ;
rdfs:comment "A cellular process phenotype in which any process of cellular component organization at the cellular level is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000407 , obo:PHIPO_0000929 .
obo:CL_4052045 a rdfs:Class ;
rdfs:label "steroidogenic stromal cell of ovary" ;
rdfs:comment "A stromal cell that is part of the ovarian stroma, characterized by its ability to synthesize steroid hormones." ;
rdfs:subClassOf obo:CL_0000499 , obo:CL_0002132 .
obo:GO_0008277 a rdfs:Class ;
rdfs:label "regulation of G protein-coupled receptor signaling pathway" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0065007 .
obo:GO_0046825 a rdfs:Class ;
rdfs:label "regulation of protein export from nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm." ;
rdfs:subClassOf obo:GO_0033157 , obo:GO_0046822 , obo:GO_0065007 .
obo:GO_1902809 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle fiber differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation." ;
rdfs:subClassOf obo:GO_0010830 , obo:GO_0065007 , obo:GO_2001014 .
obo:CHEBI_59814 a rdfs:Class ;
rdfs:label "L-alpha-amino acid anion" ;
rdfs:comment "Conjugate base of an L-α-amino acid arising from deprotonation of the C-1 carboxy group." ;
rdfs:subClassOf obo:CHEBI_33558 .
obo:GO_0072577 a rdfs:Class ;
rdfs:label "endothelial cell apoptotic process" ;
rdfs:comment "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." ;
rdfs:subClassOf obo:GO_0006915 .
obo:GO_0044091 a rdfs:Class ;
rdfs:label "membrane biogenesis" ;
rdfs:comment "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." ;
rdfs:subClassOf obo:GO_0044085 .
obo:PHIPO_0000666 a rdfs:Class ;
rdfs:label "resistance to cyclosporine A"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cyclosporine A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_81853 a rdfs:Class ;
rdfs:label "fenhexamid" ;
rdfs:comment "An aromatic amide resulting from the formal condensation of the carboxy group of 1-methylcyclohexanecarboxylic acid with the amino group of 4-amino-2,3-dichlorophenol." ;
rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_29347 , obo:CHEBI_33853 , obo:CHEBI_62733 , obo:CHEBI_87015 .
obo:GO_2000542 a rdfs:Class ;
rdfs:label "negative regulation of gastrulation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." ;
rdfs:subClassOf obo:GO_0010470 , obo:GO_0045992 , obo:GO_0065007 .
obo:PHIPO_0000102 a rdfs:Class ;
rdfs:label "obsolete loss of motility" .
obo:CHEBI_27412 a rdfs:Class ;
rdfs:label "gentamycin C1" ;
rdfs:subClassOf obo:CHEBI_28417 .
obo:GO_1904057 a rdfs:Class ;
rdfs:label "negative regulation of sensory perception of pain" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain." ;
rdfs:subClassOf obo:GO_0031645 , obo:GO_0051930 , obo:GO_0065007 .
obo:CL_2000068 a rdfs:Class ;
rdfs:label "pericardium fibroblast" ;
rdfs:comment "Any fibroblast that is part of a pericardium." ;
rdfs:subClassOf obo:CL_0000057 .
obo:UBERON_0012254 a rdfs:Class ;
rdfs:label "abdominal aorta artery" ;
rdfs:comment "An artery that originates from the abdominal aorta." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0004573 .
obo:GO_0075009 a rdfs:Class ;
rdfs:label "germ tube formation" ;
rdfs:comment "Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0009743 a rdfs:Class ;
rdfs:label "response to carbohydrate" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_1901700 .
obo:GO_0008356 a rdfs:Class ;
rdfs:label "asymmetric cell division" ;
rdfs:comment "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." ;
rdfs:subClassOf obo:GO_0051301 .
obo:PHIPO_0001139 a rdfs:Class ;
rdfs:label "decreased number of septa in asexual spore"@en ;
rdfs:comment "A single species phenotype where the frequency of occurrence of septum within an asexual spore is decreased." ;
rdfs:subClassOf obo:PHIPO_0000127 , obo:PHIPO_0001137 .
obo:CHEBI_75592 a rdfs:Class ;
rdfs:label "L-cycloserine" ;
rdfs:comment "A 4-amino-1,2-oxazolidin-3-one that has S configuration. An antibiotic isolated from Erwinia uredovora." ;
rdfs:subClassOf obo:CHEBI_23503 .
obo:PHIPO_0000332 a rdfs:Class ;
rdfs:label "pathogen colonization of host phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype which affects the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:UBERON_0003557 a rdfs:Class ;
rdfs:label "midbrain arachnoid mater" ;
rdfs:comment "An arachnoid mater that is part of a midbrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002362 , obo:UBERON_0003288 .
obo:CL_2000072 a rdfs:Class ;
rdfs:label "adipose microvascular endothelial cell" ;
rdfs:comment "Any microvascular endothelial cell that is part of a adipose tissue." ;
rdfs:subClassOf obo:CL_0002320 , obo:CL_2000008 .
obo:GO_0060325 a rdfs:Class ;
rdfs:label "face morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_23981 a rdfs:Class ;
rdfs:label "ethanolamines" ;
rdfs:subClassOf obo:CHEBI_22478 .
obo:GO_0070230 a rdfs:Class ;
rdfs:label "positive regulation of lymphocyte apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070228 , obo:GO_2000108 .
obo:GO_0042562 a rdfs:Class ;
rdfs:label "hormone binding" ;
rdfs:comment "Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor." ;
rdfs:subClassOf obo:GO_0005488 .
obo:GO_0015172 a rdfs:Class ;
rdfs:label "acidic amino acid transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3." ;
rdfs:subClassOf obo:GO_0015171 .
obo:UBERON_0003409 a rdfs:Class ;
rdfs:label "gland of tongue" ;
rdfs:comment "Any of the mucous, serous, or mixed glands that empty their secretions onto the surface of the tongue." ;
rdfs:subClassOf obo:UBERON_0002530 , obo:UBERON_0010047 .
obo:CHEBI_5653 a rdfs:Class ;
rdfs:label "hemiacetal" ;
rdfs:comment "A compound having the general formula RR'C(OH)OR'' (R'' ≠ H)." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:GO_0021819 a rdfs:Class ;
rdfs:label "layer formation in cerebral cortex" ;
rdfs:comment "The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0061308 a rdfs:Class ;
rdfs:label "cardiac neural crest cell development involved in heart development" ;
rdfs:comment "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart." ;
rdfs:subClassOf obo:GO_0014032 .
obo:PATO_0001401 a rdfs:Class ;
rdfs:label "oligopotent" ;
rdfs:comment "A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity." ;
rdfs:subClassOf obo:PATO_0001397 .
obo:PHIPO_0000822 a rdfs:Class ;
rdfs:label "sensitive to antimycin A"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to antimycin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0030857 a rdfs:Class ;
rdfs:label "negative regulation of epithelial cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." ;
rdfs:subClassOf obo:GO_0030856 , obo:GO_0045596 , obo:GO_0065007 .
obo:CL_0000159 a rdfs:Class ;
rdfs:label "seromucus secreting cell" ;
rdfs:subClassOf obo:CL_0000151 .
obo:CHEBI_35693 a rdfs:Class ;
rdfs:label "dicarboxylic acid anion" ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:GO_0120187 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to chromatin" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903829 , obo:GO_1905634 .
obo:GO_0051130 a rdfs:Class ;
rdfs:label "positive regulation of cellular component organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0051128 , obo:GO_0065007 .
obo:PATO_0000502 a rdfs:Class ;
rdfs:label "delayed" ;
rdfs:comment "A quality of a process which starts later than the natural start time or the reference process." ;
rdfs:subClassOf obo:PATO_0002325 .
obo:CHEBI_68452 a rdfs:Class ;
rdfs:label "azole" ;
rdfs:comment "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen." ;
rdfs:subClassOf obo:CHEBI_38101 , obo:CHEBI_38179 .
obo:GO_0051461 a rdfs:Class ;
rdfs:label "positive regulation of corticotropin secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell." ;
rdfs:subClassOf obo:GO_0051240 , obo:GO_0051459 , obo:GO_0065007 , obo:GO_0090277 .
obo:GO_0071168 a rdfs:Class ;
rdfs:label "protein localization to chromatin" ;
rdfs:comment "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0034502 .
obo:CL_4307084 a rdfs:Class ;
rdfs:label "CHOR NN_1 Tbc1d1 choroid plexus epithelial cell (Mmus)" ;
rdfs:comment "A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus), Tbc1d1 (Mmus). It is distinguished from other CHOR NN cells by expression of Tbc1d1. These cells are located in the Cerebellum, brain , in or close to the regions: Paraflocculus, choroid plexus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5264 CHOR NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301608 .
obo:CL_4033050 a rdfs:Class ;
rdfs:label "catecholaminergic neuron" ;
rdfs:comment "A neuron that releases catecholamine as a neurotransmitter." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000540 .
obo:CHEBI_86484 a rdfs:Class ;
rdfs:label "methoxyacrylate strobilurin antifungal agent" ;
rdfs:comment "Any strobilurin antifungal agent that contains a methoxyacrylate group." ;
rdfs:subClassOf obo:CHEBI_25248 , obo:CHEBI_51702 , obo:CHEBI_86482 .
obo:CL_4307043 a rdfs:Class ;
rdfs:label "Astro-TE NN_2 Mcm6 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mcm6 (Mmus), Egfr (Mmus), Pcsk6 (Mmus). It is distinguished from other Astro-TE NN_2 cells by expression of Mcm6. These cells are located in the Hippocampal region , in or close to the regions: Dentate gyrus, molecular layer, Dentate gyrus, polymorph layer, Dentate gyrus, granule cell layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5223 Astro-TE NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301592 .
obo:CHEBI_50047 a rdfs:Class ;
rdfs:label "organic amino compound" ;
rdfs:comment "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:CHEBI_87015 a rdfs:Class ;
rdfs:label "anilide fungicide" ;
rdfs:comment "Any amide fungicide whose structure contains an anilide group." ;
rdfs:subClassOf obo:CHEBI_60600 .
obo:UBERON_0010135 a rdfs:Class ;
rdfs:label "sensory circumventricular organ" ;
rdfs:comment "A circumventricular organ that is capable of monitoring the levels of substances to the cerebrospinal fluid." ;
rdfs:subClassOf obo:UBERON_0005408 .
obo:GO_0007528 a rdfs:Class ;
rdfs:label "neuromuscular junction development" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0050808 .
obo:GO_0010032 a rdfs:Class ;
rdfs:label "meiotic chromosome condensation" ;
rdfs:comment "Compaction of chromatin structure prior to meiosis in eukaryotic cells." ;
rdfs:subClassOf obo:GO_0030261 , obo:GO_0070192 .
obo:PATO_0045054 a rdfs:Class ;
rdfs:label "normal length" ;
rdfs:comment "A length quality which is relatively normal or average" ;
rdfs:subClassOf obo:PATO_0000122 , obo:PATO_0045050 .
obo:CHEBI_25675 a rdfs:Class ;
rdfs:label "oligomycin" ;
rdfs:comment "Any of the 26-membered ring macrolides produced by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases." ;
rdfs:subClassOf obo:CHEBI_25105 , obo:CHEBI_72600 .
obo:GO_0060295 a rdfs:Class ;
rdfs:label "regulation of cilium movement involved in cell motility" ;
rdfs:comment "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility." ;
rdfs:subClassOf obo:GO_0003352 , obo:GO_0065007 , obo:GO_1902019 .
obo:UBERON_0004581 a rdfs:Class ;
rdfs:label "systemic venous system" ;
rdfs:comment "The part of the venous system that drains the general body tissues[Kardong]." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:PHIPO_0000784 a rdfs:Class ;
rdfs:label "sensitive to nisin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to nisin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0120034 a rdfs:Class ;
rdfs:label "positive regulation of plasma membrane bounded cell projection assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly." ;
rdfs:subClassOf obo:GO_0031346 , obo:GO_0044089 , obo:GO_0065007 , obo:GO_0120032 .
obo:GO_0014015 a rdfs:Class ;
rdfs:label "positive regulation of gliogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia." ;
rdfs:subClassOf obo:GO_0014013 , obo:GO_0050769 , obo:GO_0065007 .
obo:CHEBI_83748 a rdfs:Class ;
rdfs:label "2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol" ;
rdfs:comment "A tertiary alcohol that is butan-2-ol substituted by a 4-chlorophenyl group at position 2, a cyclopropyl group at position 3 and a 1H-1,2,4-triazol-1-yl group at position 1." ;
rdfs:subClassOf obo:CHEBI_26878 , obo:CHEBI_35727 , obo:CHEBI_51454 , obo:CHEBI_83403 .
obo:GO_0035735 a rdfs:Class ;
rdfs:label "intraciliary transport involved in cilium assembly" ;
rdfs:comment "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly." ;
rdfs:subClassOf obo:GO_0042073 .
obo:RO_0002341 a rdf:Property ;
rdfs:label "results in transport along"@en ;
rdfs:comment "Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l " ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002337 .
obo:GO_0043502 a rdfs:Class ;
rdfs:label "regulation of muscle adaptation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of muscle adaptation." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 , obo:GO_0090257 .
obo:GO_0030278 a rdfs:Class ;
rdfs:label "regulation of ossification" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 .
obo:CHEBI_33792 a rdfs:Class ;
rdfs:label "canonical ribonucleoside residue" ;
rdfs:subClassOf obo:CHEBI_33791 .
obo:GO_2000241 a rdfs:Class ;
rdfs:label "regulation of reproductive process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of reproductive process." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:GO_0060843 a rdfs:Class ;
rdfs:label "venous endothelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0060837 .
obo:UBERON_0003837 a rdfs:Class ;
rdfs:label "thoracic segment connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a thorax [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003586 .
obo:GO_0007606 a rdfs:Class ;
rdfs:label "sensory perception of chemical stimulus" ;
rdfs:comment "The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." ;
rdfs:subClassOf obo:GO_0007600 .
obo:GO_0060441 a rdfs:Class ;
rdfs:label "epithelial tube branching involved in lung morphogenesis" ;
rdfs:comment "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." ;
rdfs:subClassOf obo:GO_0048754 .
obo:GO_1902533 a rdfs:Class ;
rdfs:label "positive regulation of intracellular signal transduction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." ;
rdfs:subClassOf obo:GO_0009967 , obo:GO_0065007 , obo:GO_1902531 .
obo:PHIPO_0000971 a rdfs:Class ;
rdfs:label "abolished formation of autophagosomes"@en ;
rdfs:comment "A single organism phenotype observed in the vegetative growth phase of the life cycle in which the ability of the organism to form autophagosomes is abolished (they were present and are now absent) (GO:0005776)." ;
rdfs:subClassOf obo:PHIPO_0000973 .
obo:UBERON_0003942 a rdfs:Class ;
rdfs:label "somatosensory system" ;
rdfs:comment "The sensory system for the sense of touch and pain." ;
rdfs:subClassOf obo:UBERON_0001032 .
obo:UBERON_0004151 a rdfs:Class ;
rdfs:label "cardiac chamber" ;
rdfs:comment "A cardiac chamber surrounds an enclosed cavity within the heart." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:CHEBI_84087 a rdfs:Class ;
rdfs:label "human urinary metabolite" ;
rdfs:comment "Any metabolite (endogenous or exogenous) found in human urine samples." ;
rdfs:subClassOf obo:CHEBI_77746 .
obo:CHEBI_52433 a rdfs:Class ;
rdfs:label "piperacillin(1-)" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:CL_4307095 a rdfs:Class ;
rdfs:label "COP NN_1 Bmp4 committed oligodendrocyte precursor (Mmus)" ;
rdfs:comment "A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Bmp4 (Mmus), Mob3b (Mmus). It is distinguished from other COP NN_1 cells by expression of Bmp4, Mob3b. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5275 COP NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301611 .
obo:GO_0051905 a rdfs:Class ;
rdfs:label "establishment of pigment granule localization" ;
rdfs:comment "The directed movement of a pigment granule to a specific location." ;
rdfs:subClassOf obo:GO_0051650 .
obo:NCBITaxon_7711 a rdfs:Class ;
rdfs:label "Chordata" ;
rdfs:subClassOf obo:NCBITaxon_33511 .
obo:PHIPO_0000738 a rdfs:Class ;
rdfs:label "sensitive to spectinomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to spectinomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_50266 a rdfs:Class ;
rdfs:label "prodrug" ;
rdfs:comment "A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug." ;
rdfs:subClassOf obo:CHEBI_136859 , obo:CHEBI_23888 .
obo:CHEBI_33662 a rdfs:Class ;
rdfs:label "annulene" ;
rdfs:comment "A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms." ;
rdfs:subClassOf obo:CHEBI_33664 .
obo:UBERON_0000476 a rdfs:Class ;
rdfs:label "acellular anatomical structure" ;
rdfs:comment "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." ;
rdfs:subClassOf obo:UBERON_0000001 .
obo:CL_0011115 a rdfs:Class ;
rdfs:label "precursor cell" ;
rdfs:comment "A cell that, by division or terminal differentiation, can give rise to other cell types." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0045602 a rdfs:Class ;
rdfs:label "negative regulation of endothelial cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation." ;
rdfs:subClassOf obo:GO_0030857 , obo:GO_0045601 , obo:GO_0065007 .
obo:UBERON_0003103 a rdfs:Class ;
rdfs:label "compound organ" ;
rdfs:comment "Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:UBERON_0001663 a rdfs:Class ;
rdfs:label "cerebral vein" ;
rdfs:comment "The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The external veins are the superior cerebral veins, inferior cerebral veins, and middle cerebral vein. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0003499 .
obo:PHIPO_0001365 a rdfs:Class ;
rdfs:label "resistance to bixafen" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to bixafen. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_2000097 a rdfs:Class ;
rdfs:label "midbrain dopaminergic neuron" ;
rdfs:comment "Any dopaminergic neuron that is part of a midbrain." ;
rdfs:subClassOf obo:CL_0000700 , obo:CL_2000029 .
obo:CHEBI_32877 a rdfs:Class ;
rdfs:label "primary amine" ;
rdfs:comment "A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group." ;
rdfs:subClassOf obo:CHEBI_32952 , obo:CHEBI_50994 .
obo:CHEBI_33543 a rdfs:Class ;
rdfs:label "sulfonate" ;
rdfs:comment "The sulfur oxoanion formed by deprotonation of sulfonic acid." ;
rdfs:subClassOf obo:CHEBI_33482 .
obo:GO_0043933 a rdfs:Class ;
rdfs:label "protein-containing complex organization" ;
rdfs:comment "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." ;
rdfs:subClassOf obo:GO_0016043 .
obo:GO_0045926 a rdfs:Class ;
rdfs:label "negative regulation of growth" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." ;
rdfs:subClassOf obo:GO_0040008 , obo:GO_0048519 , obo:GO_0065007 .
obo:GO_0048732 a rdfs:Class ;
rdfs:label "gland development" ;
rdfs:comment "The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:GO_0046670 a rdfs:Class ;
rdfs:label "positive regulation of retinal cell programmed cell death" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina." ;
rdfs:subClassOf obo:GO_0043068 , obo:GO_0046668 , obo:GO_0051094 , obo:GO_0065007 .
obo:GO_0042116 a rdfs:Class ;
rdfs:label "macrophage activation" ;
rdfs:comment "A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0002274 .
obo:UBERON_0004271 a rdfs:Class ;
rdfs:label "outflow tract pericardium" ;
rdfs:comment "A pericardium that is part of a outflow tract [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002407 .
obo:PATO_0070060 a rdfs:Class ;
rdfs:label "quality of interaction of a substance with electromagnetic radiation" ;
rdfs:comment "A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength." ;
rdfs:subClassOf obo:PATO_0002198 .
obo:UBERON_0003379 a rdfs:Class ;
rdfs:label "cardiac muscle of right atrium" ;
rdfs:comment "A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001133 , obo:UBERON_0004490 .
obo:UBERON_0000922 a rdfs:Class ;
rdfs:label "embryo" ;
rdfs:comment "Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." ;
rdfs:subClassOf obo:UBERON_0000468 .
obo:RO_0002489 a rdf:Property ;
rdfs:label "existence starts with" ;
rdfs:comment "x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y)." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002488 .
obo:RO_0002493 a rdf:Property ;
rdfs:label "existence ends with" ;
rdfs:comment "x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y)." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002492 .
obo:UBERON_0009577 a rdfs:Class ;
rdfs:label "metencephalon sulcus limitans" ;
rdfs:comment "A sulcus limitans of neural tube that is part of a future metencephalon." ;
rdfs:subClassOf obo:UBERON_0005478 .
obo:GO_1904821 a rdfs:Class ;
rdfs:label "chloroplast disassembly" ;
rdfs:comment "The disaggregation of a chloroplast into its constituent components." ;
rdfs:subClassOf obo:GO_0009658 , obo:GO_0022411 , obo:GO_1903008 .
obo:PHIPO_0000746 a rdfs:Class ;
rdfs:label "sensitive to voriconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to voriconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0005728 a rdfs:Class ;
rdfs:label "extraembryonic mesoderm" ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0005292 , obo:UBERON_0007524 .
obo:GO_0098969 a rdfs:Class ;
rdfs:label "neurotransmitter receptor transport to postsynaptic membrane" ;
rdfs:comment "The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles." ;
rdfs:subClassOf obo:GO_0015031 , obo:GO_0097120 , obo:GO_0098877 , obo:GO_0099072 , obo:GO_1903540 .
obo:CHEBI_149836 a rdfs:Class ;
rdfs:label "tigecycline" ;
rdfs:comment "Tetracycline in which the hydroxy group at position 5 and the methyl group at position 6 are replaced by hydrogen, and with a dimethylamino substituent and an (N-tert-butylglycyl)amino substituent at positions 7 and 9, respectively. A glycylcycline antibiotic, it has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. It is used for the intravenous treatment of complicated skin and skin structure infections caused by susceptible organisms." ;
rdfs:subClassOf obo:CHEBI_139592 , obo:CHEBI_26895 .
obo:GO_0009941 a rdfs:Class ;
rdfs:label "chloroplast envelope" ;
rdfs:comment "The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." ;
rdfs:subClassOf obo:GO_0009526 .
obo:PHIPO_0001241 a rdfs:Class ;
rdfs:label "decreased chitinase activity"@en ;
rdfs:comment "A single species molecular function phenotype in which the observed rate of chitinase activity is decreased." ;
rdfs:subClassOf obo:PHIPO_0000436 .
obo:PR_P08920 a rdfs:Class ;
rdfs:label "T-cell surface antigen CD2 (mouse)" ;
rdfs:comment "A CD2 molecule that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001083 , obo:PR_000029032 .
obo:PR_000001810 a rdfs:Class ;
rdfs:label "CSF-1/PDGF receptor-type tyrosine-protein kinase" ;
rdfs:comment "A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PR_P55284 a rdfs:Class ;
rdfs:label "cadherin-5 (mouse)" ;
rdfs:comment "A cadherin-5 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001444 , obo:PR_000029032 .
obo:CL_1100001 a rdfs:Class ;
rdfs:label "secretory epithelial cell"@en ;
rdfs:comment "An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0000151 .
obo:UBERON_0008885 a rdfs:Class ;
rdfs:label "right putamen" ;
rdfs:comment "A putamen that is part of a right cerebral hemisphere." ;
rdfs:subClassOf obo:UBERON_0001874 .
obo:GO_0030182 a rdfs:Class ;
rdfs:label "neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuron." ;
rdfs:subClassOf obo:GO_0030154 .
obo:PHIPO_0000653 a rdfs:Class ;
rdfs:label "resistance to fluconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fluconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0072657 a rdfs:Class ;
rdfs:label "protein localization to membrane" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a specific location in a membrane." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0051668 .
obo:GO_0000961 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial RNA catabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ;
rdfs:subClassOf obo:GO_0000960 , obo:GO_0065007 , obo:GO_1902369 .
obo:UBERON_0003114 a rdfs:Class ;
rdfs:label "pharyngeal arch 3" ;
rdfs:comment "The third branchial arch contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus." ;
rdfs:subClassOf obo:UBERON_0002539 .
obo:GO_0061055 a rdfs:Class ;
rdfs:label "myotome development" ;
rdfs:comment "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0014888 a rdfs:Class ;
rdfs:label "striated muscle adaptation" ;
rdfs:comment "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." ;
rdfs:subClassOf obo:GO_0043500 .
obo:UBERON_0000167 a rdfs:Class ;
rdfs:label "oral cavity" ;
rdfs:comment "Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present)." ;
rdfs:subClassOf obo:UBERON_0000464 , obo:UBERON_0002553 .
obo:RO_0001015 a rdf:Property ;
rdfs:label "location of"@en ;
rdfs:comment "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ;
rdfs:range .
obo:PHIPO_0000946 a rdfs:Class ;
rdfs:label "decreased cellular reactive oxygen species level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0000945 , obo:PHIPO_0001035 .
obo:CL_0013000 a rdfs:Class ;
rdfs:label "forebrain radial glial cell"@en ;
rdfs:comment "Any radial glial cell that is part of some forebrain." ;
rdfs:subClassOf obo:CL_0000681 .
obo:PHIPO_0000931 a rdfs:Class ;
rdfs:label "cell wall organization or biogenesis phenotype"@en ;
rdfs:comment "A phenotype that affects cell wall organization or biogenesis." ;
rdfs:subClassOf obo:PHIPO_0000930 .
obo:GO_1905321 a rdfs:Class ;
rdfs:label "negative regulation of mesenchymal stem cell migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration." ;
rdfs:subClassOf obo:GO_0030336 , obo:GO_0065007 , obo:GO_1905320 .
obo:CL_0002076 a rdfs:Class ;
rdfs:label "endo-epithelial cell" ;
rdfs:comment "An epithelial cell derived from endoderm." ;
rdfs:subClassOf obo:CL_0000066 .
obo:GO_0021603 a rdfs:Class ;
rdfs:label "cranial nerve formation" ;
rdfs:comment "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0045599 a rdfs:Class ;
rdfs:label "negative regulation of fat cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0045598 , obo:GO_0065007 .
obo:GO_2000035 a rdfs:Class ;
rdfs:label "regulation of stem cell division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of stem cell division." ;
rdfs:subClassOf obo:GO_0051302 , obo:GO_0065007 .
obo:UBERON_0036422 a rdfs:Class ;
rdfs:label "wall of pulmonary artery" ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0000415 .
obo:CHEBI_35850 a rdfs:Class ;
rdfs:label "sulfone" ;
rdfs:comment "An organosulfur compound having the structure RS(=O)2R (R ≠ H)." ;
rdfs:subClassOf obo:CHEBI_33261 .
obo:GO_0014031 a rdfs:Class ;
rdfs:label "mesenchymal cell development" ;
rdfs:comment "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:GO_1903979 a rdfs:Class ;
rdfs:label "negative regulation of microglial cell activation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation." ;
rdfs:subClassOf obo:GO_0043031 , obo:GO_0065007 , obo:GO_0150079 , obo:GO_1903978 .
obo:CHEBI_62247 a rdfs:Class ;
rdfs:label "(1R,2S)-epoxypropylphosphonate(1-)" ;
rdfs:comment "An organophosphonate oxoanion obtained by deprotonation of one of the two phosphonate OH groups of (1R,2S)-epoxypropylphosphonic acid; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_59635 .
obo:CHEBI_50909 a rdfs:Class ;
rdfs:label "nephrotoxic agent" ;
rdfs:comment "A role played by any chemical compound (natural or synthetic) exhibiting itself through the ability to induce damage to the kidneys." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:CHEBI_83708 a rdfs:Class ;
rdfs:label "(R)-flutriafol" ;
rdfs:subClassOf obo:CHEBI_83707 .
obo:CHEBI_50319 a rdfs:Class ;
rdfs:label "nucleotide residue" ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:CHEBI_473992 a rdfs:Class ;
rdfs:label "nystatin A1" ;
rdfs:comment "A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species." ;
rdfs:subClassOf obo:CHEBI_59676 .
obo:PHIPO_0001230 a rdfs:Class ;
rdfs:label "host defense-induced phenolic compound present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the host phenolic compounds usually present during infection are normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:GO_0002627 a rdfs:Class ;
rdfs:label "positive regulation of T cell antigen processing and presentation" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002579 , obo:GO_0002625 , obo:GO_0002711 , obo:GO_0065007 .
obo:PHIPO_0000379 a rdfs:Class ;
rdfs:label "abnormal cell wall organization"@en ;
rdfs:comment "A cellular process phenotype in which cell wall organization is abnormal. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall." ;
rdfs:subClassOf obo:PHIPO_0000400 .
obo:GO_1902252 a rdfs:Class ;
rdfs:label "positive regulation of erythrocyte apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process." ;
rdfs:subClassOf obo:GO_0033034 , obo:GO_0065007 , obo:GO_1902250 .
obo:UBERON_0006799 a rdfs:Class ;
rdfs:label "glandular epithelium" ;
rdfs:comment "An epithelium that is composed primarily of secretory cells." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:UBERON_0005358 a rdfs:Class ;
rdfs:label "ventricle of nervous system" ;
rdfs:comment "A layer in the central nervous system that lines system of communicating cavities in the brain and spinal cord." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:CHEBI_33859 a rdfs:Class ;
rdfs:label "aromatic carboxylic acid" ;
rdfs:comment "Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring." ;
rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_33659 .
obo:UBERON_0007286 a rdfs:Class ;
rdfs:label "presumptive floor plate" ;
rdfs:comment "A presumptive structure that has the potential to develop into a floor plate." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:CHEBI_36434 a rdfs:Class ;
rdfs:label "octadecatrienoate" ;
rdfs:comment "A C18, straight-chain, unsaturated long-chain fatty acid anion and the conjugate base of its corresponding octadecatrienoic acid, formed by deprotonation of the carboxylic acid group." ;
rdfs:subClassOf obo:CHEBI_57560 , obo:CHEBI_59203 , obo:CHEBI_76567 .
obo:GO_0007077 a rdfs:Class ;
rdfs:label "mitotic nuclear membrane disassembly" ;
rdfs:comment "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis." ;
rdfs:subClassOf obo:GO_0051081 , obo:GO_1903047 .
obo:PHIPO_0000693 a rdfs:Class ;
rdfs:label "resistance to carbapenems"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to carbapenems. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0005694 a rdfs:Class ;
rdfs:label "chromosome" ;
rdfs:comment "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." ;
rdfs:subClassOf obo:GO_0043232 .
obo:PHIPO_0001270 a rdfs:Class ;
rdfs:label "sensitive to calcium ion starvation"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to calcium ion starvation. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide." ;
rdfs:subClassOf obo:PHIPO_0001098 .
obo:GO_0060760 a rdfs:Class ;
rdfs:label "positive regulation of response to cytokine stimulus" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of a response to cytokine stimulus." ;
rdfs:subClassOf obo:GO_0048584 , obo:GO_0060759 , obo:GO_0065007 .
obo:UBERON_0005057 a rdfs:Class ;
rdfs:label "immune organ" ;
rdfs:comment "An organ that is part of a immune system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:PHIPO_0000172 a rdfs:Class ;
rdfs:label "obsolete abolished pathogen host interaction RNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which RNA binding by a gene product does not occur, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:GO_0055022 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle tissue growth" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth." ;
rdfs:subClassOf obo:GO_0055021 , obo:GO_0061117 , obo:GO_0065007 .
obo:CL_4301582 a rdfs:Class ;
rdfs:label "CBX Purkinje Gaba_1 Purkinje cell (Mmus)" ;
rdfs:comment "A Purkinje cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pcp2 (Mmus), Stk17b (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1152 CBX Purkinje Gaba_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300353 .
obo:PHIPO_0000148 a rdfs:Class ;
rdfs:label "altered DNA binding specificity"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which a gene product that normally binds to a specific DNA sequence instead binds to a different sequence when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000145 .
obo:GO_1904693 a rdfs:Class ;
rdfs:label "midbrain morphogenesis" ;
rdfs:comment "The developmental process by which a midbrain is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:UBERON_0034876 a rdfs:Class ;
rdfs:label "future neurohypophysis" ;
rdfs:comment "The outgrowth of neuroectoderm located on the floor of the embryonic hypothalamus that gives rise to the neurohypophysis (posterior lobe) of the pituitary gland." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_0070062 a rdfs:Class ;
rdfs:label "extracellular exosome" ;
rdfs:comment "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." ;
rdfs:subClassOf obo:GO_1903561 .
obo:PHIPO_0000190 a rdfs:Class ;
rdfs:label "delayed host-defense induced lesion formation by host hypersensitive response"@en ;
rdfs:comment "A phenotype where there is an delayed process of host tissue cell death, leading to the formation of a host lesion, which is induced by the host activating its own hypersensitive response in defense against a pathogen." ;
rdfs:subClassOf obo:PHIPO_0000192 , obo:PHIPO_0000985 .
obo:PHIPO_0001445 a rdfs:Class ;
rdfs:label "decreased level of deoxynivalenol"@en ;
rdfs:comment "A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is decreased." ;
rdfs:subClassOf obo:PHIPO_0001031 .
obo:GO_0044409 a rdfs:Class ;
rdfs:label "entry into host" ;
rdfs:comment "Penetration by an organism into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0051701 .
obo:GO_0005794 a rdfs:Class ;
rdfs:label "Golgi apparatus" ;
rdfs:comment "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways." ;
rdfs:subClassOf obo:GO_0043231 .
obo:CHEBI_36388 a rdfs:Class ;
rdfs:label "saturated organic heterocyclic parent" ;
rdfs:subClassOf obo:CHEBI_35552 .
obo:GO_0090425 a rdfs:Class ;
rdfs:label "acinar cell differentiation" ;
rdfs:comment "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini." ;
rdfs:subClassOf obo:GO_0002067 , obo:GO_0030154 .
obo:GO_0021984 a rdfs:Class ;
rdfs:label "adenohypophysis development" ;
rdfs:comment "The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_73539 a rdfs:Class ;
rdfs:label "naphthyridine derivative" ;
rdfs:comment "Any organonitrogen heterocyclic compound that is a derivative of a naphthyridine." ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 .
obo:GO_0032352 a rdfs:Class ;
rdfs:label "positive regulation of hormone metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0032350 , obo:GO_0065007 .
obo:GO_0140252 a rdfs:Class ;
rdfs:label "regulation protein catabolic process at postsynapse" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0140250 .
obo:UBERON_0004667 a rdfs:Class ;
rdfs:label "interventricular septum muscular part" ;
rdfs:comment "The muscular portion of the wall between the two lower chambers of the heart." ;
rdfs:subClassOf obo:UBERON_0002385 .
obo:NCBITaxon_1338369 a rdfs:Class ;
rdfs:label "Dipnotetrapodomorpha" ;
rdfs:subClassOf obo:NCBITaxon_8287 .
obo:GO_0042998 a rdfs:Class ;
rdfs:label "positive regulation of Golgi to plasma membrane protein transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." ;
rdfs:subClassOf obo:GO_0042996 , obo:GO_0051222 , obo:GO_0065007 , obo:GO_1903078 .
obo:CHEBI_49020 a rdfs:Class ;
rdfs:label "hormone antagonist" ;
rdfs:comment "A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." ;
rdfs:subClassOf obo:CHEBI_48706 , obo:CHEBI_51061 .
obo:GO_0071383 a rdfs:Class ;
rdfs:label "cellular response to steroid hormone stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." ;
rdfs:subClassOf obo:GO_0032870 , obo:GO_0048545 , obo:GO_0070887 , obo:GO_0071396 .
obo:UBERON_0003309 a rdfs:Class ;
rdfs:label "floor plate of diencephalon" ;
rdfs:comment "A floor plate that is part of a diencephalon [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0002616 , obo:UBERON_0003306 .
obo:CHEBI_76730 a rdfs:Class ;
rdfs:label "EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH‒NH2 group of donors (EC 1.4.*.*)." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:CHEBI_24753 a rdfs:Class ;
rdfs:label "hygromycin" ;
rdfs:subClassOf obo:CHEBI_22479 , obo:CHEBI_22507 .
obo:GO_0030213 a rdfs:Class ;
rdfs:label "hyaluronan biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine." ;
rdfs:subClassOf obo:GO_0006024 , obo:GO_0009058 , obo:GO_0030212 .
obo:CHEBI_35359 a rdfs:Class ;
rdfs:label "carboxamidine" ;
rdfs:comment "Compounds having the structure RC(=NR)NR2. The term is used as a suffix in systematic nomenclature to denote the ‒C(=NH)NH2 group including its carbon atom." ;
rdfs:subClassOf obo:CHEBI_2634 , obo:CHEBI_35352 .
obo:GO_1905165 a rdfs:Class ;
rdfs:label "regulation of lysosomal protein catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904350 .
obo:CL_4310136 a rdfs:Class ;
rdfs:label "STRv D1 MSN nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron (Primate)" ;
rdfs:comment "A nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D1 MSN." ;
rdfs:subClassOf obo:CL_4030051 , obo:CL_4310058 .
obo:GO_0061659 a rdfs:Class ;
rdfs:label "ubiquitin-like protein ligase activity" ;
rdfs:comment "Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate." ;
rdfs:subClassOf obo:GO_0019787 .
obo:CL_2000008 a rdfs:Class ;
rdfs:label "microvascular endothelial cell" ;
rdfs:comment "Any blood vessel endothelial cell that is part of a microvascular endothelium." ;
rdfs:subClassOf obo:CL_0000071 .
obo:GO_0010668 a rdfs:Class ;
rdfs:label "ectodermal cell differentiation" ;
rdfs:comment "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0030154 .
obo:NCBITaxon_131567 a rdfs:Class ;
rdfs:label "cellular organisms" ;
rdfs:subClassOf obo:NCBITaxon_1 .
obo:UBERON_0010059 a rdfs:Class ;
rdfs:label "hypoglossal cord" ;
rdfs:subClassOf obo:UBERON_0002036 .
obo:GO_0021544 a rdfs:Class ;
rdfs:label "subpallium development" ;
rdfs:comment "The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0061556 a rdfs:Class ;
rdfs:label "trigeminal ganglion morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of a trigeminal ganglion is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0061559 .
obo:GO_1990874 a rdfs:Class ;
rdfs:label "vascular associated smooth muscle cell proliferation" ;
rdfs:comment "The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0048659 .
obo:GO_0007163 a rdfs:Class ;
rdfs:label "establishment or maintenance of cell polarity" ;
rdfs:comment "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." ;
rdfs:subClassOf obo:GO_0009987 .
obo:UBERON_0006267 a rdfs:Class ;
rdfs:label "notochordal plate" ;
rdfs:comment "The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0002050 , obo:UBERON_0005291 , obo:UBERON_0010371 .
obo:PHIPO_0001281 a rdfs:Class ;
rdfs:label "presence of host protein phosphorylation with pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, occurs during pathogen infection (GO:0006468 protein phosphorylation)." ;
rdfs:subClassOf obo:PHIPO_0001247 .
obo:PHIPO_0000470 a rdfs:Class ;
rdfs:label "obsolete location of pathogen growth within host phenotype" .
obo:CL_0000514 a rdfs:Class ;
rdfs:label "smooth muscle myoblast" ;
rdfs:comment "A precursor cell destined to differentiate into smooth muscle myocytes." ;
rdfs:subClassOf obo:CL_0000056 .
obo:RO_0002203 a rdf:Property ;
rdfs:label "develops into"@en ;
rdfs:comment "inverse of develops from" ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002387 , obo:RO_0002388 , obo:RO_0002286 .
obo:PHIPO_0001038 a rdfs:Class ;
rdfs:label "normal level of substance in cell"@en ;
rdfs:comment "A single species cell phenotype in which the amount of a specific substance measured in a cell is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000403 .
obo:GO_0060638 a rdfs:Class ;
rdfs:label "mesenchymal-epithelial cell signaling" ;
rdfs:comment "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted." ;
rdfs:subClassOf obo:GO_0007267 .
obo:UBERON_0005665 a rdfs:Class ;
rdfs:label "3rd arch endoderm" ;
rdfs:comment "An endoderm that is part of a pharyngeal arch 3." ;
rdfs:subClassOf obo:UBERON_0000925 .
obo:GO_0033034 a rdfs:Class ;
rdfs:label "positive regulation of myeloid cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process." ;
rdfs:subClassOf obo:GO_0033032 , obo:GO_0043065 , obo:GO_0065007 .
obo:PHIPO_0000390 a rdfs:Class ;
rdfs:label "sensitive to diethofencarb"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to diethocarb. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0072598 a rdfs:Class ;
rdfs:label "protein localization to chloroplast" ;
rdfs:comment "A process in which a protein is transported to, or maintained at, a location in a chloroplast." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033365 .
obo:GO_1905956 a rdfs:Class ;
rdfs:label "positive regulation of endothelial tube morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis." ;
rdfs:subClassOf obo:GO_0051240 , obo:GO_0065007 , obo:GO_1901509 , obo:GO_1905332 .
obo:CHEBI_190509 a rdfs:Class ;
rdfs:label "imipenem zwitterion" ;
rdfs:comment "Zwitterionic form of imipenem having an anionic carboxy group and a protonated methaneimidamido group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:GO_0060294 a rdfs:Class ;
rdfs:label "cilium movement involved in cell motility" ;
rdfs:comment "Movement of cilia mediated by motor proteins that contributes to the movement of a cell." ;
rdfs:subClassOf obo:GO_0003341 .
obo:UBERON_0010329 a rdfs:Class ;
rdfs:label "paired limb/fin bud mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a limb/fin bud." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0010377 .
obo:GO_0002277 a rdfs:Class ;
rdfs:label "myeloid dendritic cell activation involved in immune response" ;
rdfs:comment "The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0001773 , obo:GO_0002275 .
obo:PHIPO_0000251 a rdfs:Class ;
rdfs:label "abnormal RNA localization"@en ;
rdfs:comment "A single organism phenotype in which the localization of an RNA in a cell is abnormal. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." ;
rdfs:subClassOf obo:PHIPO_0000249 , obo:PHIPO_0001094 .
obo:GO_0014010 a rdfs:Class ;
rdfs:label "Schwann cell proliferation" ;
rdfs:comment "The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0014009 .
obo:GO_0048570 a rdfs:Class ;
rdfs:label "notochord morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048562 .
obo:CHEBI_37143 a rdfs:Class ;
rdfs:label "organofluorine compound" ;
rdfs:comment "An organofluorine compound is a compound containing at least one carbon-fluorine bond." ;
rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_24062 .
obo:UBERON_0003052 a rdfs:Class ;
rdfs:label "midbrain-hindbrain boundary" ;
rdfs:comment "The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate." ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0007651 .
obo:CHEBI_26714 a rdfs:Class ;
rdfs:label "sodium salt" ;
rdfs:comment "Any alkali metal salt having sodium(1+) as the cation." ;
rdfs:subClassOf obo:CHEBI_26712 , obo:CHEBI_35479 .
obo:UBERON_0007204 a rdfs:Class ;
rdfs:label "brachiocephalic vasculature" ;
rdfs:comment "The vasculature consisting of brachiocephalic arteries and veins." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:CHEBI_33599 a rdfs:Class ;
rdfs:label "spiro compound" ;
rdfs:comment "A compound having one atom as the only common member of two rings." ;
rdfs:subClassOf obo:CHEBI_33635 .
a rdfs:Class ;
rdfs:label "Cerebellar cortex" ;
rdfs:subClassOf , obo:UBERON_0002129 .
obo:PR_000001867 a rdfs:Class ;
rdfs:label "interleukin-5 receptor subunit alpha" ;
rdfs:comment "A protein that is a translation product of the human IL5RA gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PHIPO_0000536 a rdfs:Class ;
rdfs:label "resistance to triclosan"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to triclosan. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0060487 a rdfs:Class ;
rdfs:label "lung epithelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030855 , obo:GO_0060479 .
obo:GO_0140096 a rdfs:Class ;
rdfs:label "catalytic activity, acting on a protein" ;
rdfs:comment "Catalytic activity that acts to modify a protein." ;
rdfs:subClassOf obo:GO_0003824 .
obo:PR_000002976 a rdfs:Class ;
rdfs:label "Ly-6-like protein" ;
rdfs:comment "A protein that is the translation product of any of the LY6 genes (LY6A-LY6I)." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0010596 a rdfs:Class ;
rdfs:label "negative regulation of endothelial cell migration" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." ;
rdfs:subClassOf obo:GO_0010594 , obo:GO_0030336 , obo:GO_0065007 .
obo:UBERON_0010083 a rdfs:Class ;
rdfs:label "future dermis" ;
rdfs:comment "Mesenchyme that has the potential to develop into a dermis." ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:PATO_0002148 a rdfs:Class ;
rdfs:label "increased virulence" ;
rdfs:comment "A virulence that is relatively high." ;
rdfs:subClassOf obo:PATO_0002146 , obo:PATO_0002305 .
obo:CHEBI_137598 a rdfs:Class ;
rdfs:label "4-aminosalicylate(1-)" ;
rdfs:comment "An aminobenzoate that is the conjugate base of 4-aminosalicylic acid, obtained by deprotonation of the carboxy group. Major miscrospecies at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_22494 , obo:CHEBI_24675 .
obo:GO_0014004 a rdfs:Class ;
rdfs:label "microglia differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system." ;
rdfs:subClassOf obo:GO_0010001 , obo:GO_0030154 , obo:GO_0030225 .
obo:UBERON_0000409 a rdfs:Class ;
rdfs:label "serous gland" ;
rdfs:comment "A gland in which the principal secretory cells are serous secreting cells." ;
rdfs:subClassOf obo:UBERON_0002365 .
obo:PHIPO_0001098 a rdfs:Class ;
rdfs:label "sensitive to stress"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to a specific stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide." ;
rdfs:subClassOf obo:PHIPO_0001217 .
obo:PHIPO_0000519 a rdfs:Class ;
rdfs:label "resistance to piperacillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to piperacillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:GO_0021579 a rdfs:Class ;
rdfs:label "medulla oblongata morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0035911 a rdfs:Class ;
rdfs:label "descending aorta morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." ;
rdfs:subClassOf obo:GO_0009653 .
obo:UBERON_0034994 a rdfs:Class ;
rdfs:label "hindbrain cortical intermediate zone" ;
rdfs:subClassOf obo:UBERON_0004040 .
obo:UBERON_0000948 a rdfs:Class ;
rdfs:label "heart" ;
rdfs:comment "A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0005181 , obo:UBERON_0007100 , obo:UBERON_0010314 .
obo:GO_0005730 a rdfs:Class ;
rdfs:label "nucleolus" ;
rdfs:comment "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." ;
rdfs:subClassOf obo:GO_0043232 .
obo:PR_000001944 a rdfs:Class ;
rdfs:label "transcription factor PU.1" ;
rdfs:comment "A protein that is a translation product of the human SPI1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0060980 a rdfs:Class ;
rdfs:label "cell migration involved in coronary vasculogenesis" ;
rdfs:comment "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0035441 , obo:GO_0060973 .
obo:CL_4310125 a rdfs:Class ;
rdfs:label "STR TAC3-PLPP4 GABA TAC3-positive striatal interneuron (Primate)" ;
rdfs:comment "A TAC3-positive striatal interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR TAC3-PLPP4 GABA." ;
rdfs:subClassOf obo:CL_4042001 .
obo:PHIPO_0000368 a rdfs:Class ;
rdfs:label "increased pathogen growth within host"@en ;
rdfs:comment "A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host is increased." ;
rdfs:subClassOf obo:PHIPO_0000954 .
obo:GO_0055117 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle contraction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac muscle contraction." ;
rdfs:subClassOf obo:GO_0006942 , obo:GO_0008016 , obo:GO_0065007 .
obo:GO_1903778 a rdfs:Class ;
rdfs:label "protein localization to vacuolar membrane" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0072657 , obo:GO_0072665 .
obo:CHEBI_47019 a rdfs:Class ;
rdfs:label "dihydroxytetrahydrofuran" ;
rdfs:subClassOf obo:CHEBI_47017 .
obo:CHEBI_35474 a rdfs:Class ;
rdfs:label "anxiolytic drug" ;
rdfs:comment "Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions." ;
rdfs:subClassOf obo:CHEBI_35473 .
obo:UBERON_0014649 a rdfs:Class ;
rdfs:label "white matter of medulla oblongata" ;
rdfs:comment "A white matter that is part of a medulla oblongata." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0014891 , obo:UBERON_0019262 .
obo:PHIPO_0001398 a rdfs:Class ;
rdfs:label "sensitive to oxidative stress"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to an oxidative stress. Typically, individuals or populations are deemed sensitive to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die)." ;
rdfs:subClassOf obo:PHIPO_0001098 .
obo:GO_0032377 a rdfs:Class ;
rdfs:label "regulation of intracellular lipid transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells." ;
rdfs:subClassOf obo:GO_0032368 , obo:GO_0032386 , obo:GO_0065007 .
obo:GO_0120254 a rdfs:Class ;
rdfs:label "olefinic compound metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0010612 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle adaptation" ;
rdfs:comment "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." ;
rdfs:subClassOf obo:GO_0043502 , obo:GO_0065007 .
obo:GO_0097049 a rdfs:Class ;
rdfs:label "motor neuron apoptotic process" ;
rdfs:comment "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0051402 .
obo:CHEBI_44976 a rdfs:Class ;
rdfs:label "phosphonic acid" ;
rdfs:comment "A phosphorus oxoacid that consists of a single pentavalent phosphorus covalently bound via single bonds to a single hydrogen and two hydroxy groups and via a double bond to an oxygen. The parent of the class of phosphonic acids." ;
rdfs:subClassOf obo:CHEBI_26069 , obo:CHEBI_33457 .
obo:GO_2000401 a rdfs:Class ;
rdfs:label "regulation of lymphocyte migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lymphocyte migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0071675 .
obo:CHEBI_32158 a rdfs:Class ;
rdfs:label "streptomycin sulfate" ;
rdfs:subClassOf obo:CHEBI_38012 .
obo:UBERON_0005499 a rdfs:Class ;
rdfs:label "rhombomere 1" ;
rdfs:comment "Hindbrain segment or neuromere 1." ;
rdfs:subClassOf obo:UBERON_0001892 .
obo:GO_0005930 a rdfs:Class ;
rdfs:label "axoneme" ;
rdfs:comment "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." ;
rdfs:subClassOf obo:GO_0110165 .
obo:PHIPO_0000321 a rdfs:Class ;
rdfs:label "obsolete abnormal effector of pathogenicity activation of host defense" ;
rdfs:comment "The host defenses activated by the pathogen are altered compared to the wild type interaction." .
obo:CHEBI_55370 a rdfs:Class ;
rdfs:label "imidazolidinone" ;
rdfs:comment "An imidazolidine containing one or more oxo groups." ;
rdfs:subClassOf obo:CHEBI_38261 .
obo:UBERON_0009125 a rdfs:Class ;
rdfs:label "petrosal placode" ;
rdfs:comment "Epibranchial placode between geniculate and nodose. Associated with 2nd branchial cleft." ;
rdfs:subClassOf obo:UBERON_0003078 .
obo:RO_0002385 a rdf:Property ;
rdfs:label "has potential to developmentally contribute to"@en ;
rdfs:comment "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y"@en ;
rdfs:domain obo:UBERON_0001062 ;
rdfs:range obo:UBERON_0001062 ;
rdfs:subPropertyOf obo:RO_0002384 .
obo:CL_0000047 a rdfs:Class ;
rdfs:label "neural stem cell" ;
rdfs:comment "An undifferentiated neural cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple central nervous system neuronal and glial cell types." ;
rdfs:subClassOf obo:CL_0002319 .
obo:GO_1902882 a rdfs:Class ;
rdfs:label "regulation of response to oxidative stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of response to oxidative stress." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080134 .
obo:CL_4072003 a rdfs:Class ;
rdfs:label "mature myelinating oligodendrocyte" ;
rdfs:comment "A post-mitotic oligodendrocyte derived from a myelin-forming oligodendrocyte (MFOL). A mature Myelinating Oligodendrocyte is a fully differentiated cell that is actively engaged in myelination. In addition to high expression of canonical myelin genes (e.g., Mbp, Plp1, Mog), a MOL can be distinguished by the expression of stage-enriched genes Grm3, Klk6, Ptgds, Anxa5, and Hopx in mice. These markers reflect the functional specialization of a mature oligodendrocyte, including roles in signalling, lipid metabolism, and myelin maintenance." ;
rdfs:subClassOf obo:CL_0000128 , obo:UBERON_0004121 .
obo:CHEBI_2634 a rdfs:Class ;
rdfs:label "amidine" ;
rdfs:comment "Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. In organic chemistry an unspecified amidine is commonly a carboxamidine." ;
rdfs:subClassOf obo:CHEBI_51143 .
obo:CHEBI_52726 a rdfs:Class ;
rdfs:label "proteasome inhibitor" ;
rdfs:comment "A drug that blocks the action of proteasomes, cellular complexes that break down proteins." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:PHIPO_0000349 a rdfs:Class ;
rdfs:label "presence of pathogen growth on host surface"@en ;
rdfs:comment "A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is present." ;
rdfs:subClassOf obo:PHIPO_0000188 .
obo:GO_0006913 a rdfs:Class ;
rdfs:label "nucleocytoplasmic transport" ;
rdfs:comment "The directed movement of molecules between the nucleus and the cytoplasm." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0051169 .
obo:GO_0048247 a rdfs:Class ;
rdfs:label "lymphocyte chemotaxis" ;
rdfs:comment "The directed movement of a lymphocyte in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0030595 , obo:GO_0072676 .
obo:PHIPO_0000306 a rdfs:Class ;
rdfs:label "obsolete abnormal effector of virulence" ;
rdfs:comment "The host defenses activated by the pathogen are altered compared to the wild type interaction" .
obo:CHEBI_36340 a rdfs:Class ;
rdfs:label "fermion" ;
rdfs:comment "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." ;
rdfs:subClassOf obo:CHEBI_36342 .
obo:CHEBI_35973 a rdfs:Class ;
rdfs:label "3-oxo monocarboxylic acid anion" ;
rdfs:comment "An oxo monocarboxylic acid anion having the oxo group located at the 3-position (R = H or organyl group)." ;
rdfs:subClassOf obo:CHEBI_35902 .
obo:PHIPO_0001434 a rdfs:Class ;
rdfs:label "sensitive to cyprodinil" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cyprodinil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1903008 a rdfs:Class ;
rdfs:label "organelle disassembly" ;
rdfs:comment "The disaggregation of an organelle into its constituent components." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0022411 .
obo:PHIPO_0001149 a rdfs:Class ;
rdfs:label "decreased reactive oxygen species production"@en ;
rdfs:comment "A single species metabolic cellular process phenotype in which the formation of reactive oxygen species (any molecules or ions formed by the incomplete one-electron reduction of oxygen) is decreased.(GO:1903409)" ;
rdfs:subClassOf obo:PHIPO_0000929 , obo:PHIPO_0001147 .
obo:GO_1903116 a rdfs:Class ;
rdfs:label "positive regulation of actin filament-based movement" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of actin filament-based movement." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0065007 , obo:GO_1903115 .
obo:CLM_1000043 a rdfs:Class ;
rdfs:label "NS forest marker set of pulmonary neuroendocrine cell (Human lung)." ;
rdfs:subClassOf obo:SO_0001260 .
obo:UBERON_0003583 a rdfs:Class ;
rdfs:label "larynx connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a larynx [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003570 .
obo:CL_0000842 a rdfs:Class ;
rdfs:label "mononuclear leukocyte" ;
rdfs:comment "A leukocyte with a single non-segmented nucleus in the mature form." ;
rdfs:subClassOf obo:CL_0000226 , obo:CL_0000738 .
obo:CHEBI_33424 a rdfs:Class ;
rdfs:label "sulfur oxoacid derivative" ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_33241 .
obo:UBERON_0000916 a rdfs:Class ;
rdfs:label "abdomen" ;
rdfs:comment "The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column." ;
rdfs:subClassOf obo:UBERON_0009569 .
obo:GO_1905456 a rdfs:Class ;
rdfs:label "regulation of lymphoid progenitor cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901532 .
obo:UBERON_0006756 a rdfs:Class ;
rdfs:label "median lingual swelling" ;
rdfs:comment "During the third week of embryological development there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings which rise from the inner surface of the mandibular arch and meet in the middle line. The site of their meeting remains post-embryonically as the median sulcus of the tongue. The tuberculum impar is said to form the central part of the tongue immediately in front of the foramen cecum, but Hammar insists that it is purely a transitory structure and forms no part of the adult tongue[WP, Gray's]." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:CL_2000019 a rdfs:Class ;
rdfs:label "compound eye photoreceptor cell" ;
rdfs:comment "Any photoreceptor cell that is part of a compound eye." ;
rdfs:subClassOf obo:CL_0000210 , obo:CL_0000287 .
obo:GO_0043393 a rdfs:Class ;
rdfs:label "regulation of protein binding" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein binding." ;
rdfs:subClassOf obo:GO_0051098 , obo:GO_0065007 .
obo:PHIPO_0001080 a rdfs:Class ;
rdfs:label "altered pathogen pigment accumulation within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the accumulation of pathogen pigmentation (coloring matter) usually present during infection differs from normal." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:GO_0055085 a rdfs:Class ;
rdfs:label "transmembrane transport" ;
rdfs:comment "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 .
obo:GO_1905672 a rdfs:Class ;
rdfs:label "negative regulation of lysosome organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0065007 , obo:GO_1905671 .
obo:GO_0042611 a rdfs:Class ;
rdfs:label "MHC protein complex" ;
rdfs:comment "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen." ;
rdfs:subClassOf obo:GO_0098797 .
obo:UBERON_0003067 a rdfs:Class ;
rdfs:label "dorsolateral placode" ;
rdfs:comment "Lateral neurogenic placodes positioned dorsal of the epibranchial placodes." ;
rdfs:subClassOf obo:UBERON_0009955 .
obo:BSPO_0000098 a rdf:Property ;
rdfs:range .
obo:UBERON_0002308 a rdfs:Class ;
rdfs:label "nucleus of brain" ;
rdfs:comment "A neural nucleus that is part of the brain." ;
rdfs:subClassOf obo:UBERON_0000125 .
obo:CHEBI_26177 a rdfs:Class ;
rdfs:label "polyene antibiotic" ;
rdfs:comment "A family of antibiotics containing a conjugated polyene moiety, usuallly isolated from some species of Streptomyces." ;
rdfs:subClassOf obo:CHEBI_33822 .
obo:UBERON_0036072 a rdfs:Class ;
rdfs:label "respiratory primordium epithelium" ;
rdfs:subClassOf obo:UBERON_0004185 , obo:UBERON_0005911 , obo:UBERON_0007499 , obo:UBERON_0009854 , obo:UBERON_0015833 .
a rdf:Property ;
rdfs:label "subdivision of" ;
rdfs:comment "placeholder relation. X = 'subdivision of A' and subdivision_of some B means that X is the mereological sum of A and B" ;
rdfs:range ;
rdfs:subPropertyOf obo:BFO_0000050 .
obo:GO_0051952 a rdfs:Class ;
rdfs:label "regulation of amine transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:UBERON_0004130 a rdfs:Class ;
rdfs:label "cerebellar layer" ;
rdfs:comment "A cortical cell layer of the cerebellum. Examples: the granular (inner+outer) layer, molecular layer, Purkinje cell layer, and the ventricular layer of the embryo." ;
rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0016548 .
obo:GO_1990188 a rdfs:Class ;
rdfs:label "euchromatin binding" ;
rdfs:comment "Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin." ;
rdfs:subClassOf obo:GO_0003682 , obo:GO_0005488 .
obo:GO_0120276 a rdfs:Class ;
rdfs:label "regulation of cerebral blood circulation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cerebral blood circulation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903522 .
obo:GO_1904962 a rdfs:Class ;
rdfs:label "plastid to vacuole vesicle-mediated transport" ;
rdfs:comment "The vesicle-mediated and directed movement of substances from plastid to vacuole." ;
rdfs:subClassOf obo:GO_0007034 , obo:GO_0010496 , obo:GO_0016192 , obo:GO_0016482 .
obo:GO_0032891 a rdfs:Class ;
rdfs:label "negative regulation of organic acid transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032890 , obo:GO_0051051 , obo:GO_0065007 .
obo:UBERON_0005863 a rdfs:Class ;
rdfs:label "cartilaginous condensation" ;
rdfs:comment "Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes." ;
rdfs:subClassOf obo:UBERON_0005856 .
obo:PHIPO_0000425 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction pathogen carbohydrate binding phenotype" ;
rdfs:comment "A pathogen host interaction phenotype which affects the binding of carbohydrate to protein." .
obo:GO_0060623 a rdfs:Class ;
rdfs:label "regulation of chromosome condensation" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." ;
rdfs:subClassOf obo:GO_0033044 , obo:GO_0065007 .
obo:CHEBI_33558 a rdfs:Class ;
rdfs:label "alpha-amino-acid anion" ;
rdfs:comment "An amino-acid anion obtained by deprotonation of any alpha-amino acid." ;
rdfs:subClassOf obo:CHEBI_37022 .
obo:GO_0015807 a rdfs:Class ;
rdfs:label "L-amino acid transport" ;
rdfs:comment "The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0006865 , obo:GO_0046942 , obo:GO_0071705 .
obo:GO_0014866 a rdfs:Class ;
rdfs:label "skeletal myofibril assembly" ;
rdfs:comment "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0030239 .
obo:CL_0000295 a rdfs:Class ;
rdfs:label "somatotropin secreting cell" ;
rdfs:comment "A peptide hormone secreting cell that produces growth hormone, somatotropin." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000167 .
obo:PHIPO_0000671 a rdfs:Class ;
rdfs:label "resistance to spectinomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to spectinomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0033554 a rdfs:Class ;
rdfs:label "cellular response to stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0051716 .
obo:PHIPO_0000768 a rdfs:Class ;
rdfs:label "sensitive to thiabendazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to thiabendazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000138 a rdfs:Class ;
rdfs:label "altered protein binding specificity"@en ;
rdfs:comment "A single species molecular function phenotype in which a mutation causes a gene product to bind to one or more proteins with different specificity from normal. For example, a protein may bind to a protein in a mutant that it does not bind in wild type. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000133 .
obo:PHIPO_0000642 a rdfs:Class ;
rdfs:label "resistance to plumbagin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to plumbagin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0001659 a rdfs:Class ;
rdfs:label "temperature homeostasis" ;
rdfs:comment "A homeostatic process in which an organism modulates its internal body temperature." ;
rdfs:subClassOf obo:GO_0048871 .
obo:GO_0045727 a rdfs:Class ;
rdfs:label "positive regulation of translation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0010628 , obo:GO_0051247 , obo:GO_0065007 .
obo:PATO_0001405 a rdfs:Class ;
rdfs:label "anucleate" ;
rdfs:comment "A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus." ;
rdfs:subClassOf obo:PATO_0001404 .
obo:UBERON_0006304 a rdfs:Class ;
rdfs:label "future trigeminal ganglion" ;
rdfs:comment "See: https://github.com/obophenotype/mouse-anatomy-ontology/issues/13 and https://github.com/obophenotype/uberon/issues/693 -- consider merging into trigeminal ganglion, as this complicates the model" ;
rdfs:subClassOf obo:UBERON_0003869 .
obo:UBERON_0009522 a rdfs:Class ;
rdfs:label "lateral lingual swelling epithelium" ;
rdfs:comment "An epithelium that is part of a lateral lingual swelling." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0000490 , obo:UBERON_0003929 , obo:UBERON_0005291 .
obo:GO_0048534 a rdfs:Class ;
rdfs:label "hematopoietic or lymphoid organ development" ;
rdfs:comment "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." ;
rdfs:subClassOf obo:GO_0048513 .
obo:CHEBI_28417 a rdfs:Class ;
rdfs:label "gentamycin C" ;
rdfs:subClassOf obo:CHEBI_17833 .
obo:GO_1903828 a rdfs:Class ;
rdfs:label "negative regulation of protein localization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0048523 , obo:GO_0065007 .
obo:CHEBI_33352 a rdfs:Class ;
rdfs:label "manganese group element atom" ;
rdfs:subClassOf obo:CHEBI_33561 .
obo:PHIPO_0000830 a rdfs:Class ;
rdfs:label "sensitive to ofloxacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_39213 a rdfs:Class ;
rdfs:label "avermectin insecticide" ;
rdfs:subClassOf obo:CHEBI_39209 , obo:CHEBI_39220 .
obo:GO_0043270 a rdfs:Class ;
rdfs:label "positive regulation of monoatomic ion transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0043269 , obo:GO_0051050 , obo:GO_0065007 .
obo:UBERON_0005723 a rdfs:Class ;
rdfs:label "floor plate spinal cord region" ;
rdfs:comment "A multi-tissue structure that is part of a spinal cord and is part of a floor plate." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0001948 , obo:UBERON_0003306 .
obo:GO_0032388 a rdfs:Class ;
rdfs:label "positive regulation of intracellular transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0048522 , obo:GO_0051050 , obo:GO_0065007 .
obo:CHEBI_76729 a rdfs:Class ;
rdfs:label "EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*)." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:CHEBI_37806 a rdfs:Class ;
rdfs:label "penicillanic acid" ;
rdfs:comment "A penam that consists of 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane bearing a carboxy group at position 2 and having (2S,5R)-configuration." ;
rdfs:subClassOf obo:CHEBI_25865 .
obo:UBERON_4200230 a rdfs:Class ;
rdfs:label "surface of bone" ;
rdfs:comment "An anatomical surface that is part of a bone." ;
rdfs:subClassOf obo:UBERON_0006984 .
obo:CL_2000086 a rdfs:Class ;
rdfs:label "neocortex basket cell" ;
rdfs:comment "Any basket cell that is part of a neocortex." ;
rdfs:subClassOf obo:CL_0000118 , obo:CL_0010011 .
obo:GO_1902838 a rdfs:Class ;
rdfs:label "regulation of nuclear migration along microtubule" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of nuclear migration along microtubule." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902513 .
obo:CHEBI_62868 a rdfs:Class ;
rdfs:label "hepatoprotective agent" ;
rdfs:comment "Any compound that is able to prevent damage to the liver." ;
rdfs:subClassOf obo:CHEBI_50267 .
obo:GO_0044464 a rdfs:Class ;
rdfs:label "obsolete cell part" ;
rdfs:comment "OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms." .
obo:PHIPO_0001387 a rdfs:Class ;
rdfs:label "normal growth on phenamacril" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to phenamacril (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PHIPO_0001319 a rdfs:Class ;
rdfs:label "resistance to metalaxyl"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to metalaxyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001456 a rdfs:Class ;
rdfs:label "susceptibility to pathogen"@en ;
rdfs:comment "A quality of an organism describing the extent to which it is prone to infection, colonization, or disease development following exposure to a pathogen." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:PHIPO_0001423 a rdfs:Class ;
rdfs:label "resistance to imazalil" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to imazalil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1901219 a rdfs:Class ;
rdfs:label "regulation of cardiac chamber morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000826 .
obo:GO_0048333 a rdfs:Class ;
rdfs:label "mesodermal cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell." ;
rdfs:subClassOf obo:GO_0030154 .
obo:UBERON_0036244 a rdfs:Class ;
rdfs:label "secretion of serous membrane" ;
rdfs:comment "A transudate found in the serous sac." ;
rdfs:subClassOf obo:UBERON_0007779 .
obo:RO_0001025 a rdf:Property ;
rdfs:label "located in"@en ;
rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
rdfs:range .
a rdf:Property ;
rdfs:label "filtered through" ;
rdfs:comment "Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity." ;
rdfs:range .
obo:GO_0051093 a rdfs:Class ;
rdfs:label "negative regulation of developmental process" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0050793 , obo:GO_0065007 .
obo:PATO_0001159 a rdfs:Class ;
rdfs:label "concentrated" ;
rdfs:comment "A concentration quality inhering in a bearer by virtue of the bearer's exhibiting concentration." ;
rdfs:subClassOf obo:PATO_0000033 .
obo:RO_0015012 a rdf:Property ;
rdfs:label "reciprocal of" ;
rdfs:comment "q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e." ;
rdfs:range .
obo:COB_0000080 a rdfs:Class .
obo:UBERON_0027368 a rdfs:Class ;
rdfs:label "matrix compartment" ;
rdfs:comment "The larger of two chemoarchitectural compartments identified in the neostriatum through differential staining for various biochemical markers. It usually is identified through differentially high staining for acetylcholinesterase and calbinin D28K." ;
rdfs:subClassOf obo:UBERON_0025736 .
obo:GO_0071763 a rdfs:Class ;
rdfs:label "nuclear membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0061024 .
obo:GO_0035050 a rdfs:Class ;
rdfs:label "embryonic heart tube development" ;
rdfs:comment "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field." ;
rdfs:subClassOf obo:GO_0035295 , obo:GO_0048856 , obo:GO_0060429 .
obo:GO_0071695 a rdfs:Class ;
rdfs:label "anatomical structure maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0021700 .
obo:GO_1901165 a rdfs:Class ;
rdfs:label "positive regulation of trophoblast cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of trophoblast cell migration." ;
rdfs:subClassOf obo:GO_0030335 , obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1901163 , obo:GO_2000243 .
obo:GO_0090258 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial fission" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0051093 , obo:GO_0065007 , obo:GO_0090140 .
obo:PR_000001971 a rdfs:Class ;
rdfs:label "vascular endothelial growth factor receptor" ;
rdfs:comment "A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0008816 a rdfs:Class ;
rdfs:label "embryonic head" ;
rdfs:comment "A head that is part of a embryo." ;
rdfs:subClassOf obo:UBERON_0000033 .
obo:GO_0032502 a rdfs:Class ;
rdfs:label "developmental process" ;
rdfs:comment "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_0002689 a rdfs:Class ;
rdfs:label "negative regulation of leukocyte chemotaxis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0002686 , obo:GO_0002688 , obo:GO_0050922 , obo:GO_0065007 .
obo:CHEBI_38502 a rdfs:Class ;
rdfs:label "cytochrome-bc1 complex inhibitor" ;
rdfs:subClassOf obo:CHEBI_38497 .
obo:UBERON_0003502 a rdfs:Class ;
rdfs:label "neck blood vessel" ;
rdfs:comment "A blood vessel that is part of a neck [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:CL_0000569 a rdfs:Class ;
rdfs:label "cardiac mesenchymal cell" ;
rdfs:comment "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field." ;
rdfs:subClassOf obo:CL_0008019 , obo:CL_2000073 .
obo:COB_0000022 a rdfs:Class ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:CHEBI_76866 a rdfs:Class ;
rdfs:label "EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor" ;
rdfs:comment "An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using a quinone or similar as acceptor (EC 1.6.5.*)." ;
rdfs:subClassOf obo:CHEBI_76733 .
obo:GO_0003158 a rdfs:Class ;
rdfs:label "endothelium development" ;
rdfs:comment "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060429 .
obo:CL_4307070 a rdfs:Class ;
rdfs:label "beta-2 tanycyte (Mmus)" ;
rdfs:comment "A beta2-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Fndc3c1 (Mmus), Ecrg4 (Mmus). It is distinguished from other Tanycyte NN cells by expression of Ecrg4. These cells are located in the Hypothalamus, brain , in or close to the regions: Median eminence, third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5250 Tanycyte NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4042020 , obo:CL_4300362 .
obo:UBERON_0000020 a rdfs:Class ;
rdfs:label "sense organ" ;
rdfs:comment "An organ that is capable of transducing sensory stimulus to the nervous system." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:PR_000029032 a rdfs:Class ;
rdfs:label "Mus musculus protein" ;
rdfs:comment "A protein that is encoded in the genome of Mus musculus." ;
rdfs:subClassOf obo:PR_000000001 , obo:PR_000036194 .
obo:CHEBI_37404 a rdfs:Class ;
rdfs:label "elemental copper" ;
rdfs:subClassOf obo:CHEBI_23377 .
obo:GO_1905145 a rdfs:Class ;
rdfs:label "cellular response to acetylcholine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_1901699 , obo:GO_1901701 , obo:GO_1905144 .
obo:PHIPO_0000945 a rdfs:Class ;
rdfs:label "altered cellular reactive oxygen species level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell differs from normal." ;
rdfs:subClassOf obo:PHIPO_0000944 .
obo:PHIPO_0001371 a rdfs:Class ;
rdfs:label "sensitive to pyrimorph" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrimorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0043455 a rdfs:Class ;
rdfs:label "regulation of secondary metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_0051447 a rdfs:Class ;
rdfs:label "negative regulation of meiotic cell cycle" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0045786 , obo:GO_0051445 , obo:GO_0065007 , obo:GO_2000242 .
obo:GO_0021594 a rdfs:Class ;
rdfs:label "rhombomere formation" ;
rdfs:comment "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CHEBI_53784 a rdfs:Class ;
rdfs:label "antispasmodic drug" ;
rdfs:comment "A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder." ;
rdfs:subClassOf obo:CHEBI_51371 .
obo:UBERON_0008896 a rdfs:Class ;
rdfs:label "post-hyoid pharyngeal arch" ;
rdfs:comment "A pharyngeal arch that is posterior to the hyoid arch. i.e. any pharyngeal arch with a number 3 or higher." ;
rdfs:subClassOf obo:UBERON_0002539 .
obo:BSPO_0000099 a rdf:Property ;
rdfs:range .
obo:PHIPO_0000631 a rdfs:Class ;
rdfs:label "resistance to cefepime"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cefepime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_33703 a rdfs:Class ;
rdfs:label "amino-acid cation" ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_33702 .
obo:CHEBI_36816 a rdfs:Class ;
rdfs:label "oxime O-ether" ;
rdfs:comment "O-organyl oximes R2C=NOR' (R' ≠ H)." ;
rdfs:subClassOf obo:CHEBI_25698 , obo:CHEBI_35352 .
obo:PHIPO_0000682 a rdfs:Class ;
rdfs:label "resistance to propiconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to propiconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000514 a rdfs:Class ;
rdfs:label "population viability phenotype"@en ;
rdfs:comment "A single organism cell population phenotype that reflects the proportion of the population that survive and develop normally." ;
rdfs:subClassOf obo:PHIPO_0000509 .
obo:CL_2000046 a rdfs:Class ;
rdfs:label "ventricular cardiac muscle cell" ;
rdfs:comment "Any cardiac muscle cell that is part of a cardiac ventricle." ;
rdfs:subClassOf obo:CL_0000746 .
obo:GO_0009536 a rdfs:Class ;
rdfs:label "plastid" ;
rdfs:comment "Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid." ;
rdfs:subClassOf obo:GO_0043231 .
obo:GO_0003215 a rdfs:Class ;
rdfs:label "cardiac right ventricle morphogenesis" ;
rdfs:comment "The process in which the right cardiac ventricle is generated and organized." ;
rdfs:subClassOf obo:GO_0003208 , obo:GO_0009653 .
obo:GO_2001016 a rdfs:Class ;
rdfs:label "positive regulation of skeletal muscle cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0065007 , obo:GO_2001014 .
obo:GO_0014861 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle contraction via regulation of action potential" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes." ;
rdfs:subClassOf obo:GO_0014819 , obo:GO_0050789 , obo:GO_0098900 .
obo:PHIPO_0001000 a rdfs:Class ;
rdfs:label "abnormal pathogen swollen terminal hyphae during cell to cell migration"@en ;
rdfs:comment "A pathogen host interaction phenotype where the morphology of the pathogen terminal hyphae during host colonization is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0000334 , obo:PHIPO_0000999 .
obo:GO_0060351 a rdfs:Class ;
rdfs:label "cartilage development involved in endochondral bone morphogenesis" ;
rdfs:comment "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones." ;
rdfs:subClassOf obo:GO_0051216 .
obo:GO_1904117 a rdfs:Class ;
rdfs:label "cellular response to vasopressin" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_0071375 , obo:GO_1904116 .
obo:GO_0002711 a rdfs:Class ;
rdfs:label "positive regulation of T cell mediated immunity" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity." ;
rdfs:subClassOf obo:GO_0002708 , obo:GO_0002709 , obo:GO_0002824 , obo:GO_0065007 .
obo:PATO_0000169 a rdfs:Class ;
rdfs:label "viability" ;
rdfs:comment "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:UBERON_0000055 a rdfs:Class ;
rdfs:label "vessel" ;
rdfs:comment "A tubular structure that contains, conveys body fluid, such as blood or lymph." ;
rdfs:subClassOf obo:UBERON_0004111 .
obo:CHEBI_35294 a rdfs:Class ;
rdfs:label "carbopolycyclic compound" ;
rdfs:comment "A polyclic compound in which all of the ring members are carbon atoms." ;
rdfs:subClassOf obo:CHEBI_33598 , obo:CHEBI_35295 .
obo:GO_0021615 a rdfs:Class ;
rdfs:label "glossopharyngeal nerve morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0021602 .
obo:GO_0042391 a rdfs:Class ;
rdfs:label "regulation of membrane potential" ;
rdfs:comment "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." ;
rdfs:subClassOf obo:GO_0065008 .
obo:GO_0031645 a rdfs:Class ;
rdfs:label "negative regulation of nervous system process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." ;
rdfs:subClassOf obo:GO_0031644 , obo:GO_0051241 , obo:GO_0065007 .
obo:PHIPO_0001016 a rdfs:Class ;
rdfs:label "obsolete altered level of host callose deposition induced by pathogen" ;
rdfs:comment "A pathogen host interaction phenotype where any process in which callose is transported to, and/or maintained in, a specific location during the host defense response to a pathogen is abnormal. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. (GO:0052542)." .
obo:UBERON_0036289 a rdfs:Class ;
rdfs:label "anterior wall of right ventricle" ;
rdfs:comment "Region of wall of right ventricle which is continuous with the lateral and septal walls of right ventricle." ;
rdfs:subClassOf obo:UBERON_0004784 , obo:UBERON_0036286 .
obo:CHEBI_36080 a rdfs:Class ;
rdfs:label "protein" ;
rdfs:comment "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." ;
rdfs:subClassOf obo:CHEBI_33695 , obo:PR_000018263 , obo:PR_000064867 .
obo:PHIPO_0000008 a rdfs:Class ;
rdfs:label "obsolete functional pathogen effector present" ;
rdfs:comment "A phenotype where the ability of a pathogen effector to produce an infectious disease is present." .
a rdfs:Class ;
rdfs:label "Medulla" ;
rdfs:subClassOf , obo:UBERON_0001896 .
obo:PHIPO_0000661 a rdfs:Class ;
rdfs:label "resistance to sulfisoxazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to sulfisoxazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_35571 a rdfs:Class ;
rdfs:label "mancude organic heterocyclic parent" ;
rdfs:subClassOf obo:CHEBI_35552 , obo:CHEBI_35573 .
obo:PHIPO_0000834 a rdfs:Class ;
rdfs:label "sensitive to quinupristin-dalfopristin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to quinupristin-dalfopristin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CARO_0010004 a rdfs:Class .
obo:UBERON_0010255 a rdfs:Class ;
rdfs:label "3rd arch mesenchyme from neural crest" ;
rdfs:comment "Mesenchyme that develops_from a neural crest and is part of a 3rd arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005690 , obo:UBERON_0010258 , obo:UBERON_0010359 .
obo:CHEBI_48378 a rdfs:Class ;
rdfs:label "carboximidic acid" ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_48377 .
obo:UBERON_0006568 a rdfs:Class ;
rdfs:label "hypothalamic nucleus" ;
rdfs:comment "A nucleus of brain that is part of a hypothalamus." ;
rdfs:subClassOf obo:UBERON_0002308 , obo:UBERON_0006569 .
obo:GO_0098961 a rdfs:Class ;
rdfs:label "dendritic transport of ribonucleoprotein complex" ;
rdfs:comment "The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0031503 , obo:GO_0098935 .
obo:CHEBI_22917 a rdfs:Class ;
rdfs:label "phytogenic insecticide" ;
rdfs:comment "An insecticide compound naturally occurring in plants." ;
rdfs:subClassOf obo:CHEBI_24852 .
obo:GO_0051458 a rdfs:Class ;
rdfs:label "corticotropin secretion" ;
rdfs:comment "The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus." ;
rdfs:subClassOf obo:GO_0030072 , obo:GO_0046903 .
obo:CHEBI_24129 a rdfs:Class ;
rdfs:label "furans" ;
rdfs:comment "Compounds containing at least one furan ring." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 .
obo:GO_0014056 a rdfs:Class ;
rdfs:label "regulation of acetylcholine secretion, neurotransmission" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine." ;
rdfs:subClassOf obo:GO_0032222 , obo:GO_0046928 , obo:GO_0051952 , obo:GO_0065007 .
obo:GO_0048280 a rdfs:Class ;
rdfs:label "vesicle fusion with Golgi apparatus" ;
rdfs:comment "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi." ;
rdfs:subClassOf obo:GO_0006906 , obo:GO_0007030 , obo:GO_0009987 .
obo:GO_0048667 a rdfs:Class ;
rdfs:label "cell morphogenesis involved in neuron differentiation" ;
rdfs:comment "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." ;
rdfs:subClassOf obo:GO_0000902 .
obo:CHEBI_83911 a rdfs:Class ;
rdfs:label "diniconazole-M" ;
rdfs:comment "A (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol that is the active R-enantiomer of diniconazole. A fungicide used to control a range of diseases including mildew, bunts and smuts." ;
rdfs:subClassOf obo:CHEBI_83909 , obo:CHEBI_87067 .
obo:GO_0048851 a rdfs:Class ;
rdfs:label "hypophysis formation" ;
rdfs:comment "The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0070051 a rdfs:Class ;
rdfs:label "fibrinogen binding" ;
rdfs:comment "Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0044877 .
obo:UBERON_0006919 a rdfs:Class ;
rdfs:label "tongue squamous epithelium" ;
rdfs:comment "A squamous epithelium that is part of a tongue." ;
rdfs:subClassOf obo:UBERON_0002424 , obo:UBERON_0003357 , obo:UBERON_0006914 .
obo:GO_0002605 a rdfs:Class ;
rdfs:label "negative regulation of dendritic cell antigen processing and presentation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002578 , obo:GO_0002604 , obo:GO_0065007 .
obo:CHEBI_49103 a rdfs:Class ;
rdfs:label "drug metabolite" ;
rdfs:subClassOf obo:CHEBI_76967 .
obo:CL_4301575 a rdfs:Class ;
rdfs:label "Lugaro cell (Mmus)" ;
rdfs:comment "A Lugaro cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pthlh (Mmus), Tfap2b (Mmus), Rspo2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1145 CB PLI Gly-Gaba_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0011006 , obo:CL_4300349 .
obo:PR_000001004 a rdfs:Class ;
rdfs:label "CD4 molecule" ;
rdfs:comment "A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0002100 a rdfs:Class ;
rdfs:label "trunk" ;
rdfs:comment "Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present." ;
rdfs:subClassOf obo:UBERON_0011676 .
obo:PHIPO_0001027 a rdfs:Class ;
rdfs:label "decreased protein level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of protein measured in a cell is lower than normal. Total protein or a specific protein may be affected." ;
rdfs:subClassOf obo:PHIPO_0001025 , obo:PHIPO_0001035 .
obo:GO_0106110 a rdfs:Class ;
rdfs:label "vomitoxin biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats." ;
rdfs:subClassOf obo:GO_0016106 , obo:GO_0034309 , obo:GO_0042181 , obo:GO_0043386 , obo:GO_0046173 , obo:GO_0097176 , obo:GO_0120255 , obo:GO_1901503 , obo:GO_1902653 .
obo:CL_4310147 a rdfs:Class ;
rdfs:label "OB Dopa-GABA OB-Dopa-GABA (Primate)" ;
rdfs:comment "A OB-Dopa-GABA of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB Dopa-GABA." ;
rdfs:subClassOf obo:CL_0020006 .
obo:GO_0071626 a rdfs:Class ;
rdfs:label "mastication" ;
rdfs:comment "The process of biting and mashing food with the teeth prior to swallowing." ;
rdfs:subClassOf obo:GO_0022600 .
obo:GO_0005773 a rdfs:Class ;
rdfs:label "vacuole" ;
rdfs:comment "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." ;
rdfs:subClassOf obo:GO_0043231 .
obo:GO_0150031 a rdfs:Class ;
rdfs:label "regulation of protein localization to lysosome" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to lysosome." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:UBERON_0035819 a rdfs:Class ;
rdfs:label "abdominopelvic cavity" ;
rdfs:comment "The part of the ventral body cavity that is within the abdominal segment of the trunk, which encompasses the abdomen proper plus pelvic cavity." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:PHIPO_0001376 a rdfs:Class ;
rdfs:label "normal anatomical structure physical quality phenotype"@en ;
rdfs:comment "A physical anatomical structure phenotype in which the amount, distribution, morphology, or other physical characteristic of a cell part, cell, or tissue, or individual is normal in the vegetative growth phase of the life cycle (i.e. indistinguishable from wild type.)" ;
rdfs:subClassOf obo:PHIPO_0001373 .
obo:GO_0043235 a rdfs:Class ;
rdfs:label "signaling receptor complex" ;
rdfs:comment "Any protein complex that binds a signaling molecule such as a hormone, neurotransmitter, molecular pattern recognition receptor (PAMPs and DAMPS), or an intracellular messenger to initiate a change in cell function." ;
rdfs:subClassOf obo:GO_0032991 .
obo:UBERON_0000349 a rdfs:Class ;
rdfs:label "limbic system" ;
rdfs:comment "A set of midline structures surrounding the brainstem of the mammalian brain, originally described anatomically, e.g., hippocampal formation, amygdala, hypothalamus, cingulate cortex. Although the original designation was anatomical, the limbic system has come to be associated with the system in the brain subserving emotional functions. As such, it is very poorly defined and doesn't correspond closely to the anatomical meaning any longer. [BirnLex]." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:PR_000001084 a rdfs:Class ;
rdfs:label "T-cell surface glycoprotein CD8 alpha chain" ;
rdfs:comment "A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_24833 a rdfs:Class ;
rdfs:label "oxoacid" ;
rdfs:comment "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ;
rdfs:subClassOf obo:CHEBI_24651 .
obo:CHEBI_35790 a rdfs:Class ;
rdfs:label "oxazole" ;
rdfs:comment "An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom." ;
rdfs:subClassOf obo:CHEBI_38104 , obo:CHEBI_68452 .
obo:GO_0071671 a rdfs:Class ;
rdfs:label "regulation of smooth muscle cell chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis." ;
rdfs:subClassOf obo:GO_0014910 , obo:GO_0050920 , obo:GO_0065007 .
obo:PHIPO_0000866 a rdfs:Class ;
rdfs:label "sensitive to hymexazol"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to hymexazol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0110024 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle myoblast proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0110022 , obo:GO_2000288 .
obo:GO_1903037 a rdfs:Class ;
rdfs:label "regulation of leukocyte cell-cell adhesion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion." ;
rdfs:subClassOf obo:GO_0022407 , obo:GO_0065007 .
obo:PHIPO_0000088 a rdfs:Class ;
rdfs:label "obsolete normal budding" .
obo:PHIPO_0000407 a rdfs:Class ;
rdfs:label "cellular component organization phenotype"@en ;
rdfs:comment "A phenotype that affects a process of cellular component organization, i.e. the assembly, arrangement of constituent parts, or disassembly of a cellular component, that occurs at the cellular level." ;
rdfs:subClassOf obo:PHIPO_0000034 .
obo:UBERON_0003513 a rdfs:Class ;
rdfs:label "trunk blood vessel" ;
rdfs:comment "A blood vessel that is part of a trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:CL_0002191 a rdfs:Class ;
rdfs:label "granulocytopoietic cell" ;
rdfs:comment "A cell involved in the formation of a granulocyte." ;
rdfs:subClassOf obo:CL_0000839 .
obo:CL_0000335 a rdfs:Class ;
rdfs:label "mesenchyme condensation cell" ;
rdfs:comment "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors." ;
rdfs:subClassOf obo:CL_0008019 .
obo:UBERON_0013479 a rdfs:Class ;
rdfs:label "lung endothelium" ;
rdfs:comment "A blood vessel endothelium that is part of a lung [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000115 , obo:UBERON_0004638 , obo:UBERON_0004702 .
obo:CHEBI_133135 a rdfs:Class ;
rdfs:label "chromenochromene" ;
rdfs:comment "Any organic heteroolycyclic compound whose skeleton two ortho-fused chromene rings, and their derivatives." ;
rdfs:subClassOf obo:CHEBI_38166 .
obo:GO_0015179 a rdfs:Class ;
rdfs:label "L-amino acid transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids." ;
rdfs:subClassOf obo:GO_0015171 , obo:GO_0022857 , obo:GO_0046943 .
obo:GO_0030659 a rdfs:Class ;
rdfs:label "cytoplasmic vesicle membrane" ;
rdfs:comment "The lipid bilayer surrounding a cytoplasmic vesicle." ;
rdfs:subClassOf obo:GO_0012506 , obo:GO_0016020 .
obo:CL_4307101 a rdfs:Class ;
rdfs:label "NFOL NN_2 Il23a newly formed oligodendrocyte (Mmus)" ;
rdfs:comment "A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Piezo2 (Mmus), Ptprb (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Il23a, Opalin, Ptprb. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5281 NFOL NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301612 .
obo:CL_1001579 a rdfs:Class ;
rdfs:label "cerebral cortex glial cell" ;
rdfs:comment "Glial cell of cerebral cortex." ;
rdfs:subClassOf obo:CL_0000125 .
obo:GO_0003013 a rdfs:Class ;
rdfs:label "circulatory system process" ;
rdfs:comment "An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." ;
rdfs:subClassOf obo:GO_0003008 .
obo:GO_0010934 a rdfs:Class ;
rdfs:label "macrophage cytokine production" ;
rdfs:comment "The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0001816 , obo:GO_0061082 .
obo:UBERON_0004755 a rdfs:Class ;
rdfs:label "skeletal tissue" ;
rdfs:comment "A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:CL_0002144 a rdfs:Class ;
rdfs:label "capillary endothelial cell" ;
rdfs:comment "An endothelial cell found in capillaries." ;
rdfs:subClassOf obo:CL_0000071 , obo:CL_0002653 , obo:CL_2000008 .
obo:GO_0010611 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle hypertrophy" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." ;
rdfs:subClassOf obo:GO_0014743 , obo:GO_0043502 , obo:GO_0065007 .
obo:CHEBI_94759 a rdfs:Class ;
rdfs:label "6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole" ;
rdfs:subClassOf obo:CHEBI_35618 .
obo:CHEBI_51750 a rdfs:Class ;
rdfs:label "alpha,beta-unsaturated carboxylic acid amide" ;
rdfs:comment "A monocarboxylic amide of general formula R1R2C=CR3‒C(=O)NR4R5 or R1C≡C‒C(=O)NR2R3 in which the amide C=O function is conjugated to an unsaturated C-C bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:UBERON_0011004 a rdfs:Class ;
rdfs:label "pharyngeal arch cartilage" ;
rdfs:comment "A cartilage element that is part of a splanchnocranium." ;
rdfs:subClassOf obo:UBERON_0003933 , obo:UBERON_0007844 .
obo:PHIPO_0000762 a rdfs:Class ;
rdfs:label "sensitive to tigecycline"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tigecycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0001890 a rdfs:Class ;
rdfs:label "forebrain" ;
rdfs:comment "The most anterior region of the brain including both the telencephalon and diencephalon." ;
rdfs:subClassOf obo:UBERON_0002616 , obo:UBERON_0004121 .
obo:CL_4307040 a rdfs:Class ;
rdfs:label "Astro-TE NN_1 Lncpint astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Dio2 (Mmus), Lncpint (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Lncpint. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5220 Astro-TE NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301591 .
obo:PHIPO_0000627 a rdfs:Class ;
rdfs:label "resistance to copper"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to copper. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_45924 a rdfs:Class ;
rdfs:label "trimethoprim" ;
rdfs:comment "An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge." ;
rdfs:subClassOf obo:CHEBI_38338 , obo:CHEBI_51683 .
obo:GO_2000832 a rdfs:Class ;
rdfs:label "negative regulation of steroid hormone secretion" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion." ;
rdfs:subClassOf obo:GO_0032369 , obo:GO_0046888 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_2000831 .
obo:PR_000001087 a rdfs:Class ;
rdfs:label "adhesion G-protein coupled receptor" ;
rdfs:comment "A G-protein coupled receptor with a 7 transmembrane (secretin family) domain (Pfam:PF00002) preceded by an amino-terminal region containing one or more functional domains with adhesion-like motifs." ;
rdfs:subClassOf obo:PR_000030035 .
obo:GO_0090168 a rdfs:Class ;
rdfs:label "Golgi reassembly" ;
rdfs:comment "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance." ;
rdfs:subClassOf obo:GO_0007030 , obo:GO_0022607 .
obo:GO_0170038 a rdfs:Class ;
rdfs:label "proteinogenic amino acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0046394 , obo:GO_0170039 .
obo:GO_0075053 a rdfs:Class ;
rdfs:label "penetration peg formation" ;
rdfs:comment "The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0075015 .
obo:NCBITaxon_1206794 a rdfs:Class ;
rdfs:label "Ecdysozoa" ;
rdfs:subClassOf obo:NCBITaxon_33317 .
obo:GO_0033243 a rdfs:Class ;
rdfs:label "positive regulation of amine catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0033240 , obo:GO_0033241 , obo:GO_0065007 .
obo:UBERON_0010333 a rdfs:Class ;
rdfs:label "extraembryonic membrane mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a extraembryonic membrane." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0004120 , obo:UBERON_0005292 .
obo:UBERON_0036925 a rdfs:Class ;
rdfs:label "wall of eyeball" ;
rdfs:subClassOf obo:UBERON_0000060 .
obo:CL_0008053 a rdfs:Class ;
rdfs:label "circumventricular organ capillary endothelial cell" ;
rdfs:comment "A capillary endothelial cell that is part of the circumventricular organs (CVOs), characterized by fenestrations that facilitate selective permeability to molecules, distinguishing it from the non-fenestrated endothelial cells of the blood-brain barrier. This cell is integral to the unique vascular structure of CVOs, which lack a traditional blood-brain barrier. It enables bidirectional exchange of polar molecules between blood and neural tissue, supporting neuroendocrine signaling, fluid balance, and immune responses. It is marked by the expression of PLVAP, a component of the fenestral diaphragm, in both rodents and humans." ;
rdfs:subClassOf obo:CL_0000666 , obo:CL_0002144 , obo:CL_2000044 .
obo:PHIPO_0000127 a rdfs:Class ;
rdfs:label "abnormal asexual spore morphology"@en ;
rdfs:comment "A reproductive phenotype where the morphology of the asexual spore is abnormal (FAO:0000023). The product of mitosis." ;
rdfs:subClassOf obo:PHIPO_0000047 .
obo:CHEBI_4511 a rdfs:Class ;
rdfs:label "dicloxacillin" ;
rdfs:comment "A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]formyl group." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_17334 , obo:CHEBI_23697 .
obo:GO_1904352 a rdfs:Class ;
rdfs:label "positive regulation of protein catabolic process in the vacuole" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole." ;
rdfs:subClassOf obo:GO_0045732 , obo:GO_0065007 , obo:GO_1904350 .
obo:CHEBI_76853 a rdfs:Class ;
rdfs:label "EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor" ;
rdfs:comment "An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*)." ;
rdfs:subClassOf obo:CHEBI_76727 .
obo:PR_P17433 a rdfs:Class ;
rdfs:label "transcription factor PU.1 (mouse)" ;
rdfs:comment "A transcription factor PU.1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001944 , obo:PR_000029032 .
obo:PHIPO_0001068 a rdfs:Class ;
rdfs:label "survival of host organism with pathogen"@en ;
rdfs:comment "A host organism viability phenotype where the host organism survives in the presence of the pathogen." ;
rdfs:subClassOf obo:PHIPO_0001070 .
obo:CL_4307065 a rdfs:Class ;
rdfs:label "Tanycyte NN_2 Mylk3 alpha1-tanycyte (Mmus)" ;
rdfs:comment "A alpha1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dynlrb2 (Mmus), Mylk3 (Mmus), Sfta3-ps (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Mylk3. It is glutamatergic (inferred from expression of Slc17a8). These cells are located in the Hypothalamus , in or close to the regions: Periventricular hypothalamic nucleus, intermediate part . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5245 Tanycyte NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_1100001 , obo:CL_4042017 , obo:CL_4301603 .
obo:GO_0007088 a rdfs:Class ;
rdfs:label "regulation of mitotic nuclear division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitosis." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0010564 , obo:GO_0051783 , obo:GO_0065007 .
obo:PATO_0000718 a rdfs:Class ;
rdfs:label "lethal (sensu genetics)" ;
rdfs:comment "A viability quality inhering in a population by virtue of the bearer's long term survival inability." ;
rdfs:subClassOf obo:PATO_0000169 .
obo:GO_0031112 a rdfs:Class ;
rdfs:label "positive regulation of microtubule polymerization or depolymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." ;
rdfs:subClassOf obo:GO_0031110 , obo:GO_0051495 , obo:GO_0065007 .
obo:CHEBI_46844 a rdfs:Class ;
rdfs:label "N-acylpiperazine" ;
rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_32988 .
obo:NCBITaxon_314146 a rdfs:Class ;
rdfs:label "Euarchontoglires" ;
rdfs:subClassOf obo:NCBITaxon_1437010 .
obo:GO_0043230 a rdfs:Class ;
rdfs:label "extracellular organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." ;
rdfs:subClassOf obo:GO_0043226 .
obo:GO_1900131 a rdfs:Class ;
rdfs:label "negative regulation of lipid binding" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding." ;
rdfs:subClassOf obo:GO_0051100 , obo:GO_0065007 .
obo:GO_0003147 a rdfs:Class ;
rdfs:label "neural crest cell migration involved in heart formation" ;
rdfs:comment "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation." ;
rdfs:subClassOf obo:GO_0001755 , obo:GO_0060974 .
obo:GO_0051321 a rdfs:Class ;
rdfs:label "meiotic cell cycle" ;
rdfs:comment "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." ;
rdfs:subClassOf obo:GO_0007049 , obo:GO_0022414 .
obo:GO_0022626 a rdfs:Class ;
rdfs:label "cytosolic ribosome" ;
rdfs:comment "A ribosome located in the cytosol." ;
rdfs:subClassOf obo:GO_0005840 .
obo:UBERON_0008243 a rdfs:Class ;
rdfs:label "upper back muscle" ;
rdfs:comment "A muscle of back that is part of a dorsal thoracic segment of trunk." ;
rdfs:subClassOf obo:UBERON_0002324 , obo:UBERON_0003830 .
obo:GO_0045685 a rdfs:Class ;
rdfs:label "regulation of glial cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glia cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:UBERON_0012360 a rdfs:Class ;
rdfs:label "bone of jaw" ;
rdfs:comment "A bone element that is part of a jaw region." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0003462 , obo:UBERON_0013765 .
obo:CHEBI_77737 a rdfs:Class ;
rdfs:label "dexverapamil(1+)" ;
rdfs:comment "An ammonium ion resulting from the protonation of the tertiary amino group of dexverapamil." ;
rdfs:subClassOf obo:CHEBI_35274 .
obo:UBERON_3000977 a rdfs:Class ;
rdfs:label "body external integument structure" ;
rdfs:comment "Dermal, epidermal, glandular and pigment structures of the body integument." ;
rdfs:subClassOf obo:UBERON_3000961 .
obo:UBERON_0004851 a rdfs:Class ;
rdfs:label "aorta endothelium" ;
rdfs:comment "The thin layer of flat cells that line the aorta and form a barrier between circulating blood in the lumen and the rest of the vessel wall." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0004638 , obo:UBERON_0004700 .
obo:GO_0140231 a rdfs:Class ;
rdfs:label "anterograde axonal transport of neurotransmitter receptor complex" ;
rdfs:comment "The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0097120 , obo:GO_0099637 , obo:GO_0099641 .
obo:PHIPO_0000800 a rdfs:Class ;
rdfs:label "sensitive to farnesol"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to farnesol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0003344 a rdfs:Class ;
rdfs:label "pericardium morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the pericardium is generated and organized." ;
rdfs:subClassOf obo:GO_0002011 , obo:GO_0009653 , obo:GO_0048598 .
obo:UBERON_0006905 a rdfs:Class ;
rdfs:label "mandibular process mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a mandibular prominence." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005253 .
obo:CL_0000740 a rdfs:Class ;
rdfs:label "retinal ganglion cell" ;
rdfs:comment "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." ;
rdfs:subClassOf obo:CL_0000540 .
obo:CHEBI_57248 a rdfs:Class ;
rdfs:label "echinocandin" ;
rdfs:comment "Any one of a family of large lipopeptides that are inhibitors of the enzyme 1,3-β-glucan synthase, thus damaging fungal cell walls. Echinocandins are fungicidal against most Candida spp and fungistatic against Aspergillus spp." ;
rdfs:subClassOf obo:CHEBI_46895 , obo:CHEBI_86478 .
obo:GO_0002385 a rdfs:Class ;
rdfs:label "mucosal immune response" ;
rdfs:comment "An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract." ;
rdfs:subClassOf obo:GO_0002251 .
obo:PHIPO_0000978 a rdfs:Class ;
rdfs:label "sensitive to sodium chloride"@en ;
rdfs:comment "A phenotype in which a population of a single-species shows increased sensitivity to sodium chloride, manifested as an affect on the extent of population growth. (CHEBI:26710)." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_51208 a rdfs:Class ;
rdfs:label "mecillinam" ;
rdfs:comment "A penicillin in which the 6β substituent is [(azepan-1-yl)methylidene]amino; an extended-spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria." ;
rdfs:subClassOf obo:CHEBI_17334 .
obo:UBERON_0000000 a rdfs:Class ;
rdfs:label "processual entity" ;
rdfs:comment "An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." .
obo:CHEBI_25384 a rdfs:Class ;
rdfs:label "monocarboxylic acid" ;
rdfs:comment "An oxoacid containing a single carboxy group." ;
rdfs:subClassOf obo:CHEBI_33575 .
obo:UBERON_0003133 a rdfs:Class ;
rdfs:label "reproductive organ" ;
rdfs:comment "An organ involved in reproduction." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0005156 .
obo:UBERON_0000063 a rdfs:Class ;
rdfs:label "organ subunit" ;
rdfs:comment "A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:CHEBI_83925 a rdfs:Class ;
rdfs:label "non-proteinogenic alpha-amino acid" ;
rdfs:comment "Any α-amino acid which is not a member of the group of 23 proteinogenic amino acids." ;
rdfs:subClassOf obo:CHEBI_33704 , obo:CHEBI_83820 .
obo:GO_0051963 a rdfs:Class ;
rdfs:label "regulation of synapse assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ;
rdfs:subClassOf obo:GO_0050807 , obo:GO_0065007 , obo:GO_1901888 .
obo:CL_0000710 a rdfs:Class ;
rdfs:label "neurecto-epithelial cell" ;
rdfs:comment "Epithelial cells derived from neural plate and neural crest." ;
rdfs:subClassOf obo:CL_0000075 , obo:CL_0002077 .
obo:CL_0002242 a rdfs:Class ;
rdfs:label "nucleate cell" ;
rdfs:comment "A cell containing at least one nucleus." ;
rdfs:subClassOf obo:CL_0000000 .
obo:CL_0000071 a rdfs:Class ;
rdfs:label "blood vessel endothelial cell" ;
rdfs:comment "An endothelial cell that lines the vasculature." ;
rdfs:subClassOf obo:CL_0000115 , obo:CL_0002139 .
obo:UBERON_0011925 a rdfs:Class ;
rdfs:label "preganglionic autonomic fiber" ;
rdfs:comment "Nerve fibers which project from the central nervous system to autonomic ganglia. In the sympathetic division most preganglionic fibers originate with neurons in the intermediolateral column of the spinal cord, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in synapses or continue through the splanchnic nerves to the prevertebral ganglia. In the parasympathetic division the fibers originate in neurons of the brain stem and sacral spinal cord. In both divisions the principal transmitter is acetylcholine but peptide cotransmitters may also be released." ;
rdfs:subClassOf obo:UBERON_0003041 , obo:UBERON_0006134 .
obo:CHEBI_81760 a rdfs:Class ;
rdfs:label "difenoconazole" ;
rdfs:comment "A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups. A broad spectrum fungicide with novel broad-range activity used as a spray or seed treatment. It is moderately toxic to humans, mammals, birds and most aquatic organisms." ;
rdfs:subClassOf obo:CHEBI_35618 , obo:CHEBI_39430 , obo:CHEBI_59779 , obo:CHEBI_87067 , obo:CHEBI_87100 .
obo:UBERON_0011565 a rdfs:Class ;
rdfs:label "lumen of gastrointestinal system" ;
rdfs:subClassOf obo:UBERON_0002553 .
obo:CHEBI_176839 a rdfs:Class ;
rdfs:label "vitamin B3" ;
rdfs:comment "Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms)." ;
rdfs:subClassOf obo:CHEBI_75769 .
obo:GO_0051302 a rdfs:Class ;
rdfs:label "regulation of cell division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0007043 a rdfs:Class ;
rdfs:label "cell-cell junction assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a junction between cells." ;
rdfs:subClassOf obo:GO_0034329 , obo:GO_0045216 .
obo:GO_0098900 a rdfs:Class ;
rdfs:label "regulation of action potential" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ;
rdfs:subClassOf obo:GO_0042391 , obo:GO_0050789 .
obo:GO_0140251 a rdfs:Class ;
rdfs:label "regulation protein catabolic process at presynapse" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0140250 .
obo:UBERON_0036657 a rdfs:Class ;
rdfs:label "wall of fourth ventricle" ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0036661 .
obo:GO_0019725 a rdfs:Class ;
rdfs:label "cellular homeostasis" ;
rdfs:comment "Any process involved in the maintenance of an internal steady state at the level of the cell." ;
rdfs:subClassOf obo:GO_0042592 .
obo:PHIPO_0000313 a rdfs:Class ;
rdfs:label "obsolete normal effector of virulence activation of host defense" ;
rdfs:comment "The host defenses activated by the pathogen are unaltered compared to the wild type interaction" .
obo:CHEBI_33853 a rdfs:Class ;
rdfs:label "phenols" ;
rdfs:comment "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_33822 .
obo:CHEBI_71629 a rdfs:Class ;
rdfs:label "nisin" ;
rdfs:comment "A type-A lantibiotic containing 34 amino acid residues (including lanthionine (Lan), methyllanthionine (MeLan), didehydroalanine (Dha) and didehydroaminobutyric acid (Dhb)) and five thioether bridges. It is obtained by fermentation of the bacterium Lactococcus lactis and shows particular activity against Clostridium botulinum. It is used in the production of various processed foods to suppress Gram-positive spoilage and pathogenic bacteria and so extend shelf life." ;
rdfs:subClassOf obo:CHEBI_51026 , obo:CHEBI_71645 .
obo:UBERON_0005253 a rdfs:Class ;
rdfs:label "head mesenchyme" ;
rdfs:comment "Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005291 .
obo:CL_0000069 a rdfs:Class ;
rdfs:label "branched duct epithelial cell" ;
rdfs:subClassOf obo:CL_0000068 .
a rdfs:Class ;
rdfs:label "Subfornical organ" ;
rdfs:subClassOf , obo:UBERON_0002219 .
obo:PR_000001015 a rdfs:Class ;
rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45RA" ;
rdfs:comment "A receptor-type tyrosine-protein phosphatase C isoform CD45R that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-8 or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000050216 .
obo:GO_0048714 a rdfs:Class ;
rdfs:label "positive regulation of oligodendrocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045687 , obo:GO_0048713 , obo:GO_0065007 .
obo:GO_0021782 a rdfs:Class ;
rdfs:label "glial cell development" ;
rdfs:comment "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:GO_0106259 a rdfs:Class ;
rdfs:label "symbiont-mediated cell-to-cell migration in host" ;
rdfs:comment "The directional movement of a symbiont from one host cell to another." ;
rdfs:subClassOf obo:GO_0044001 .
obo:GO_0098868 a rdfs:Class ;
rdfs:label "bone growth" ;
rdfs:comment "The increase in size or mass of a bone that contributes to the shaping of that bone." ;
rdfs:subClassOf obo:GO_0035265 , obo:GO_0048589 .
obo:GO_0036293 a rdfs:Class ;
rdfs:label "response to decreased oxygen levels" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." ;
rdfs:subClassOf obo:GO_0070482 .
obo:NCBITaxon_41665 a rdfs:Class ;
rdfs:label "Neopterygii" ;
rdfs:subClassOf obo:NCBITaxon_186623 .
obo:UBERON_0005239 a rdfs:Class ;
rdfs:label "basal plate metencephalon" ;
rdfs:subClassOf obo:UBERON_0004064 .
obo:BSPO_0000102 a rdf:Property ;
rdfs:range .
obo:GO_0050870 a rdfs:Class ;
rdfs:label "positive regulation of T cell activation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of T cell activation." ;
rdfs:subClassOf obo:GO_0050863 , obo:GO_0051251 , obo:GO_0065007 , obo:GO_1903039 .
obo:PHIPO_0000779 a rdfs:Class ;
rdfs:label "sensitive to streptomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to streptomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0050808 a rdfs:Class ;
rdfs:label "synapse organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0034330 .
obo:CL_0000122 a rdfs:Class ;
rdfs:label "stellate neuron" ;
rdfs:comment "A neuron that has dendritic processes radiating from the cell body forming a star-like shape." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000029 .
obo:GO_1904266 a rdfs:Class ;
rdfs:label "regulation of Schwann cell chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis." ;
rdfs:subClassOf obo:GO_0050920 , obo:GO_0065007 , obo:GO_1900147 .
obo:CHEBI_70781 a rdfs:Class ;
rdfs:label "PPAR modulator" ;
rdfs:comment "Any compound which acts on the peroxisome proliferator-activated receptor." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:GO_0090141 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial fission" ;
rdfs:comment "Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0051094 , obo:GO_0065007 , obo:GO_0090140 .
obo:GO_0042886 a rdfs:Class ;
rdfs:label "amide transport" ;
rdfs:comment "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0071705 .
obo:UBERON_0000457 a rdfs:Class ;
rdfs:label "cavernous artery" ;
rdfs:comment "Any of several small branches of the internal carotid artery that supply the trigeminal ganglion and the walls of the cavernous and petrosal sinuses." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:CHEBI_33658 a rdfs:Class ;
rdfs:label "arene" ;
rdfs:comment "Any monocyclic or polycyclic aromatic hydrocarbon." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_33663 .
a rdfs:Class ;
rdfs:label "PLCH1" ;
rdfs:subClassOf obo:SO_0000704 .
obo:GO_0001840 a rdfs:Class ;
rdfs:label "neural plate development" ;
rdfs:comment "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060429 .
obo:CHEBI_38498 a rdfs:Class ;
rdfs:label "mitochondrial NADH:ubiquinone reductase inhibitor" ;
rdfs:subClassOf obo:CHEBI_25355 , obo:CHEBI_38503 .
obo:UBERON_0000977 a rdfs:Class ;
rdfs:label "pleura" ;
rdfs:comment "The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion)." ;
rdfs:subClassOf obo:UBERON_0000042 .
obo:GO_0002582 a rdfs:Class ;
rdfs:label "positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." ;
rdfs:subClassOf obo:GO_0002579 , obo:GO_0002580 , obo:GO_0065007 .
obo:CHEBI_51354 a rdfs:Class ;
rdfs:label "benzylpenicillin(1-)" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:PHIPO_0000015 a rdfs:Class ;
rdfs:label "reduced virulence" ;
rdfs:comment "A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is decreased (i.e. fewer symptoms than normal)." ;
rdfs:subClassOf obo:PHIPO_0000011 .
obo:GO_0071495 a rdfs:Class ;
rdfs:label "cellular response to endogenous stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." ;
rdfs:subClassOf obo:GO_0009719 .
obo:GO_0099098 a rdfs:Class ;
rdfs:label "microtubule polymerization based movement" ;
rdfs:comment "The movement of a cellular component as a result of microtubule polymerization." ;
rdfs:subClassOf obo:GO_0007018 .
obo:GO_0140039 a rdfs:Class ;
rdfs:label "cell-cell adhesion in response to extracellular stimulus" ;
rdfs:comment "The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus." ;
rdfs:subClassOf obo:GO_0098609 .
obo:GO_0043938 a rdfs:Class ;
rdfs:label "positive regulation of sporulation" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure." ;
rdfs:subClassOf obo:GO_0043937 , obo:GO_0051094 , obo:GO_0065007 .
obo:GO_0018995 a rdfs:Class ;
rdfs:label "host cellular component" ;
rdfs:comment "Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection." ;
rdfs:subClassOf obo:GO_0044217 .
obo:GO_0021546 a rdfs:Class ;
rdfs:label "rhombomere development" ;
rdfs:comment "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_2007013 a rdfs:Class ;
rdfs:label "preplacodal ectoderm" ;
rdfs:comment "Non neural ectoderm that surrounds the presumptive neural plate and gives rise to neurogenic placodes." ;
rdfs:subClassOf obo:UBERON_0005497 .
obo:CHEBI_51422 a rdfs:Class ;
rdfs:label "organodiyl group" ;
rdfs:comment "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." ;
rdfs:subClassOf obo:CHEBI_51446 .
obo:UBERON_0014454 a rdfs:Class ;
rdfs:label "visceral abdominal adipose tissue" ;
rdfs:comment "Subcutaneous adipose tissue that is located in the peritoneal cavity." ;
rdfs:subClassOf obo:UBERON_0001013 , obo:UBERON_0007808 .
obo:RO_0002007 a rdf:Property ;
rdfs:label "bounding layer of"@en ;
rdfs:comment """X outer_layer_of Y iff:
. X :continuant that bearer_of some PATO:laminar
. X part_of Y
. exists Z :surface
. X has_boundary Z
. Z boundary_of Y
has_boundary: http://purl.obolibrary.org/obo/RO_0002002
boundary_of: http://purl.obolibrary.org/obo/RO_0002000""" ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:BFO_0000050 .
obo:PHIPO_0000534 a rdfs:Class ;
rdfs:label "resistance to actinomycin D"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to actinomycin D. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1903358 a rdfs:Class ;
rdfs:label "regulation of Golgi organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of Golgi organization." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:GO_0007506 a rdfs:Class ;
rdfs:label "gonadal mesoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0007498 , obo:GO_0048856 , obo:GO_0060485 .
obo:GO_0002158 a rdfs:Class ;
rdfs:label "osteoclast proliferation" ;
rdfs:comment "The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0070661 .
obo:CHEBI_17076 a rdfs:Class ;
rdfs:label "streptomycin" ;
rdfs:comment "A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class" ;
rdfs:subClassOf obo:CHEBI_26788 , obo:CHEBI_87113 , obo:CHEBI_87114 .
obo:UBERON_0004062 a rdfs:Class ;
rdfs:label "neural tube marginal layer" ;
rdfs:comment "The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter." ;
rdfs:subClassOf obo:UBERON_0005162 .
obo:GO_0007040 a rdfs:Class ;
rdfs:label "lysosome organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0080171 .
obo:GO_0042417 a rdfs:Class ;
rdfs:label "dopamine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ;
rdfs:subClassOf obo:GO_0006584 , obo:GO_0008152 .
obo:GO_0045988 a rdfs:Class ;
rdfs:label "negative regulation of striated muscle contraction" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction." ;
rdfs:subClassOf obo:GO_0006942 , obo:GO_0045932 , obo:GO_0065007 .
obo:CHEBI_137982 a rdfs:Class ;
rdfs:label "tertiary ammonium ion" ;
rdfs:comment "An organic cation obtained by protonation of the amino group of any tertiary amino compound." ;
rdfs:subClassOf obo:CHEBI_25697 .
obo:GO_2000195 a rdfs:Class ;
rdfs:label "negative regulation of female gonad development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905940 , obo:GO_2000194 .
obo:GO_0061300 a rdfs:Class ;
rdfs:label "cerebellum vasculature development" ;
rdfs:comment "The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0001944 , obo:GO_0048856 .
obo:PR_000007597 a rdfs:Class ;
rdfs:label "protein c-Fos" ;
rdfs:comment "A protein that is a translation product of the human FOS gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_35716 a rdfs:Class ;
rdfs:label "C-nitro compound" ;
rdfs:comment "A nitro compound having the nitro group (‒NO2) attached to a carbon atom." ;
rdfs:subClassOf obo:CHEBI_35715 , obo:CHEBI_72695 .
obo:UBERON_0002743 a rdfs:Class ;
rdfs:label "basal forebrain" ;
rdfs:comment "A region of the brain consisting of ventral and rostral subcortical regions of the telencephalon, including among others, the basal ganglia, septal nuclei, amygdala, ventral pallidum, substantia innominata, and basal nucleus of Meynert." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_0007019 a rdfs:Class ;
rdfs:label "microtubule depolymerization" ;
rdfs:comment "The removal of tubulin heterodimers from one or both ends of a microtubule." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0031109 , obo:GO_0051261 , obo:GO_0097435 .
obo:UBERON_0001009 a rdfs:Class ;
rdfs:label "circulatory system" ;
rdfs:comment "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:CHEBI_48154 a rdfs:Class ;
rdfs:label "sulfur oxide" ;
rdfs:subClassOf obo:CHEBI_24836 , obo:CHEBI_26835 .
obo:GO_0005776 a rdfs:Class ;
rdfs:label "autophagosome" ;
rdfs:comment "A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy." ;
rdfs:subClassOf obo:GO_0005773 .
obo:PHIPO_0001291 a rdfs:Class ;
rdfs:label "resistance to fenpicoxamid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fenpicoxamid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0061626 a rdfs:Class ;
rdfs:label "pharyngeal arch artery morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048844 .
obo:CL_0010017 a rdfs:Class ;
rdfs:label "zygote"@en ;
rdfs:comment "A zygote in a plant or an animal." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_1904958 a rdfs:Class ;
rdfs:label "positive regulation of midbrain dopaminergic neuron differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904340 , obo:GO_1904956 .
obo:GO_0021704 a rdfs:Class ;
rdfs:label "locus ceruleus morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PHIPO_0000934 a rdfs:Class ;
rdfs:label "abnormal nucleus"@en ;
rdfs:comment "A single organism phenotype in which the amount, distribution, or morphology of all or part of the nucleus is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000415 .
obo:UBERON_0001529 a rdfs:Class ;
rdfs:label "brachiocephalic artery" ;
rdfs:comment "The short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery." ;
rdfs:subClassOf obo:UBERON_0004573 .
obo:GO_0060936 a rdfs:Class ;
rdfs:label "cardiac fibroblast cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." ;
rdfs:subClassOf obo:GO_0048468 , obo:GO_0055006 .
obo:GO_1905653 a rdfs:Class ;
rdfs:label "positive regulation of artery morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of artery morphogenesis." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_1905651 .
obo:CHEBI_84003 a rdfs:Class ;
rdfs:label "(R)-triadimefon" ;
rdfs:comment "A 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one that is the (R)-enantiomer of triadimefon." ;
rdfs:subClassOf obo:CHEBI_84002 .
obo:GO_0086015 a rdfs:Class ;
rdfs:label "SA node cell action potential" ;
rdfs:comment "An action potential that occurs in a sinoatrial node cardiac muscle cell." ;
rdfs:subClassOf obo:GO_0001508 , obo:GO_0086001 .
obo:CL_0000558 a rdfs:Class ;
rdfs:label "reticulocyte" ;
rdfs:comment "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." ;
rdfs:subClassOf obo:CL_0000764 .
obo:CL_4030046 a rdf:Property ;
rdfs:label "lacks_plasma_membrane_part" ;
rdfs:range .
obo:GO_0007389 a rdfs:Class ;
rdfs:label "pattern specification process" ;
rdfs:comment "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0045785 a rdfs:Class ;
rdfs:label "positive regulation of cell adhesion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell adhesion." ;
rdfs:subClassOf obo:GO_0030155 , obo:GO_0048522 , obo:GO_0065007 .
obo:PHIPO_0000649 a rdfs:Class ;
rdfs:label "resistance to methicillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to methicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:GO_0040007 a rdfs:Class ;
rdfs:label "growth" ;
rdfs:comment "The increase in size or mass of an entire organism, a part of an organism or a cell." ;
rdfs:subClassOf obo:GO_0008150 .
obo:PHIPO_0001214 a rdfs:Class ;
rdfs:label "hyphal growth phenotype"@en ;
rdfs:comment "A single species growth phenotype which affects or involves normal or abnormal size, extent or rate of directional growth of the hyphae of an individual organism." ;
rdfs:subClassOf obo:PHIPO_0000402 .
obo:GO_2000725 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051153 , obo:GO_0065007 , obo:GO_1905207 .
obo:PHIPO_0000484 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction phenotype" ;
rdfs:comment "A pathogen host interaction phenotype which is abnormal (i.e. different than wild-type)." .
obo:GO_0021758 a rdfs:Class ;
rdfs:label "putamen development" ;
rdfs:comment "The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048857 .
obo:CHEBI_47881 a rdfs:Class ;
rdfs:label "3-oxo monocarboxylic acid" ;
rdfs:subClassOf obo:CHEBI_35871 .
obo:CHEBI_32600 a rdfs:Class ;
rdfs:label "tetracene" ;
rdfs:comment "An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement." ;
rdfs:subClassOf obo:CHEBI_35297 , obo:CHEBI_51270 .
obo:GO_0051047 a rdfs:Class ;
rdfs:label "positive regulation of secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ;
rdfs:subClassOf obo:GO_0051046 , obo:GO_0051050 , obo:GO_0065007 .
obo:GO_1905937 a rdfs:Class ;
rdfs:label "negative regulation of germ cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1905936 .
obo:UBERON_0022293 a rdfs:Class ;
rdfs:label "reproductive gland secretion" ;
rdfs:comment "A portion of organism substance that is secreted by a reproductive gland." ;
rdfs:subClassOf obo:UBERON_0000463 .
obo:UBERON_0002111 a rdfs:Class ;
rdfs:label "artery smooth muscle tissue" ;
rdfs:comment "A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004237 , obo:UBERON_0004695 .
obo:CHEBI_31014 a rdfs:Class ;
rdfs:label "tetracosanoate" ;
rdfs:comment "A straight-chain saturated fatty acid anion that is the conjugate base of tetracosanoic acid (lignoceric acid), formed by deprotonation of the carboxy group." ;
rdfs:subClassOf obo:CHEBI_58950 , obo:CHEBI_58954 , obo:CHEBI_78128 , obo:CHEBI_83955 .
obo:PHIPO_0000170 a rdfs:Class ;
rdfs:label "obsolete chlorosis present" .
obo:CHEBI_26788 a rdfs:Class ;
rdfs:label "streptomycins" ;
rdfs:subClassOf obo:CHEBI_22479 , obo:CHEBI_22507 .
obo:GO_0051688 a rdfs:Class ;
rdfs:label "maintenance of plastid location" ;
rdfs:comment "Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0051644 , obo:GO_0051651 , obo:GO_0051657 .
obo:GO_0098813 a rdfs:Class ;
rdfs:label "nuclear chromosome segregation" ;
rdfs:comment "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." ;
rdfs:subClassOf obo:GO_0007059 .
obo:GO_0030424 a rdfs:Class ;
rdfs:label "axon" ;
rdfs:comment "The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter." ;
rdfs:subClassOf obo:GO_0043005 .
obo:PHIPO_0001300 a rdfs:Class ;
rdfs:label "sensitive to pyrrolnitrin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrrolnitrin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000839 a rdfs:Class ;
rdfs:label "sensitive to actinomycin D"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to actinomycin D. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0021700 a rdfs:Class ;
rdfs:label "developmental maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0032502 .
obo:PATO_0103000 a rdfs:Class ;
rdfs:label "quantitative" ;
rdfs:comment "A quality of an entity that can be represented numerically, including anything that can be counted, measured, or given a numerical value." ;
rdfs:subClassOf obo:PATO_0000001 .
obo:UBERON_0014404 a rdfs:Class ;
rdfs:label "female anatomical structure" ;
rdfs:comment "A part of the body present only in females." ;
rdfs:subClassOf obo:UBERON_0014402 .
obo:CL_0000457 a rdfs:Class ;
rdfs:label "biogenic amine secreting cell" ;
rdfs:subClassOf obo:CL_0000151 .
obo:UBERON_0001496 a rdfs:Class ;
rdfs:label "ascending aorta" ;
rdfs:comment "The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]." ;
rdfs:subClassOf obo:UBERON_0001515 .
obo:GO_0060218 a rdfs:Class ;
rdfs:label "hematopoietic stem cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ;
rdfs:subClassOf obo:GO_0002244 , obo:GO_0030154 , obo:GO_0048863 .
obo:GO_1904776 a rdfs:Class ;
rdfs:label "regulation of protein localization to cell cortex" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to cell cortex." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904375 .
obo:PR_000002001 a rdfs:Class ;
rdfs:label "receptor-type tyrosine-protein kinase FLT3" ;
rdfs:comment "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human FLT3 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001810 .
obo:GO_0097512 a rdfs:Class ;
rdfs:label "cardiac myofibril" ;
rdfs:comment "A cardiac myofibril is a myofibril specific to cardiac muscle cells." ;
rdfs:subClassOf obo:GO_0030016 .
obo:CHEBI_76741 a rdfs:Class ;
rdfs:label "EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*)." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:CL_0010010 a rdfs:Class ;
rdfs:label "cerebellar stellate cell" ;
rdfs:comment "A GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell receives excitatory inputs primarily from parallel fibers and plays a crucial role in feed-forward inhibition by suppressing the activity of Purkinje cells and modulating the output of the cerebellar cortex. The stellate cell is part of the local circuitry that contributes to the fine-tuning of motor coordination and a regulator of cerebellar blood flow via neurovascular coupling." ;
rdfs:subClassOf obo:CL_0000122 , obo:CL_0000691 , obo:CL_4042035 .
obo:CL_0000576 a rdfs:Class ;
rdfs:label "monocyte" ;
rdfs:comment "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells." ;
rdfs:subClassOf obo:CL_0000113 , obo:CL_0000766 , obo:CL_0011026 .
obo:PATO_0000117 a rdfs:Class ;
rdfs:label "size" ;
rdfs:comment "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:CHEBI_26816 a rdfs:Class ;
rdfs:label "carbohydrate phosphate" ;
rdfs:subClassOf obo:CHEBI_25703 , obo:CHEBI_37734 , obo:CHEBI_63299 .
obo:CHEBI_47518 a rdfs:Class ;
rdfs:label "(2S,4R)-ketoconazole" ;
rdfs:comment "A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2S,4R)-configuration." ;
rdfs:subClassOf obo:CHEBI_86411 .
obo:PHIPO_0000844 a rdfs:Class ;
rdfs:label "sensitive to propiconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to propiconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000117 a rdfs:Class ;
rdfs:label "increased pathogen growth after penetration of the barrier"@en ;
rdfs:comment "A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay is increased." ;
rdfs:subClassOf obo:PHIPO_0000031 .
obo:UBERON_0005965 a rdfs:Class ;
rdfs:label "outflow part of right atrium" ;
rdfs:comment "Outflow part of atrium which consists of wall and cavity of the outflow part of right atrium and the tricuspid valve.[FMA]." ;
rdfs:subClassOf obo:UBERON_0005946 .
a rdf:Property ;
rdfs:label "channels_into" ;
rdfs:range .
obo:CHEBI_68495 a rdfs:Class ;
rdfs:label "apoptosis inducer" ;
rdfs:comment "Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms." ;
rdfs:subClassOf obo:CHEBI_52206 .
obo:GO_0014872 a rdfs:Class ;
rdfs:label "myoblast division" ;
rdfs:comment "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ;
rdfs:subClassOf obo:GO_0051301 .
obo:GO_0046829 a rdfs:Class ;
rdfs:label "negative regulation of RNA import into nucleus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus." ;
rdfs:subClassOf obo:GO_0032240 , obo:GO_0046823 , obo:GO_0046828 , obo:GO_0065007 .
obo:UBERON_0011899 a rdfs:Class ;
rdfs:label "epimysium" ;
rdfs:comment "Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous." ;
rdfs:subClassOf obo:UBERON_0011822 .
obo:CHEBI_16336 a rdfs:Class .
obo:GO_0051984 a rdfs:Class ;
rdfs:label "positive regulation of chromosome segregation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ;
rdfs:subClassOf obo:GO_0051983 , obo:GO_0065007 , obo:GO_0090068 .
obo:PHIPO_0000740 a rdfs:Class ;
rdfs:label "sensitive to oxacillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to oxacillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:CHEBI_36623 a rdfs:Class ;
rdfs:label "4H-benzimidazole" ;
rdfs:subClassOf obo:CHEBI_36622 .
obo:UBERON_0005702 a rdfs:Class ;
rdfs:label "optic eminence mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a optic eminence." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005291 .
obo:UBERON_0002038 a rdfs:Class ;
rdfs:label "substantia nigra" ;
rdfs:comment "Predominantly gray matter midbrain structure lying dorsal to the crus cerebri and ventral to the midbrain tegmentum. It is divided into a dorsal, cellularly compact region known as the pars compacta and a more ventrally located, containing more loosely packed cells, the pars reticulata. The most lateral region of the reticulata is identified as the pars lateralis (MM)." ;
rdfs:subClassOf obo:UBERON_0009661 , obo:UBERON_0015212 .
obo:CHEBI_36587 a rdfs:Class ;
rdfs:label "organic oxo compound" ;
rdfs:comment "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." ;
rdfs:subClassOf obo:CHEBI_72695 .
obo:PHIPO_0000302 a rdfs:Class ;
rdfs:label "normal dissemination of sexual spore"@en ;
rdfs:comment "A single species phenotype where the dispersal of sexual spores is normal (FAO:0000017)." ;
rdfs:subClassOf obo:PHIPO_0000044 .
obo:PHIPO_0000019 a rdfs:Class ;
rdfs:label "inviable cell" ;
rdfs:comment "A lethal single organism cell level phenotype resulting from altering a gene product that is essential for the life of the organism." ;
rdfs:subClassOf obo:PHIPO_0001222 .
obo:GO_0006909 a rdfs:Class ;
rdfs:label "phagocytosis" ;
rdfs:comment "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." ;
rdfs:subClassOf obo:GO_0006897 .
obo:GO_0090497 a rdfs:Class ;
rdfs:label "mesenchymal cell migration" ;
rdfs:comment "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism." ;
rdfs:subClassOf obo:GO_0001667 , obo:GO_0016477 .
obo:GO_0042053 a rdfs:Class ;
rdfs:label "regulation of dopamine metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ;
rdfs:subClassOf obo:GO_0042069 , obo:GO_0065007 .
obo:PHIPO_0000155 a rdfs:Class ;
rdfs:label "decreased RNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is decreased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000152 .
obo:GO_1904139 a rdfs:Class ;
rdfs:label "regulation of microglial cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of microglial cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903975 , obo:GO_1905521 .
obo:GO_0002694 a rdfs:Class ;
rdfs:label "regulation of leukocyte activation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of leukocyte activation." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0050865 , obo:GO_0065007 .
obo:UBERON_0000446 a rdfs:Class ;
rdfs:label "septum of telencephalon" ;
rdfs:comment "Gray matter structure located on the midline of the forebrain consisting of the septum pellucidum (in some species) and the septal nuclei (Heimer, 1996)." ;
rdfs:subClassOf obo:UBERON_0005401 .
obo:CHEBI_52208 a rdfs:Class ;
rdfs:label "biophysical role" ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:UBERON_0034726 a rdfs:Class ;
rdfs:label "trunk taste bud" ;
rdfs:comment "A taste bud that is located on the skin of the trunk." ;
rdfs:subClassOf obo:UBERON_0001727 , obo:UBERON_0005177 , obo:UBERON_0034717 .
obo:GO_0048640 a rdfs:Class ;
rdfs:label "negative regulation of developmental growth" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." ;
rdfs:subClassOf obo:GO_0045926 , obo:GO_0048638 , obo:GO_0051093 , obo:GO_0065007 .
obo:GO_1902513 a rdfs:Class ;
rdfs:label "regulation of organelle transport along microtubule" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of organelle transport along microtubule." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0060632 , obo:GO_0065007 .
obo:CHEBI_15369 a rdfs:Class ;
rdfs:label "actinomycin" ;
rdfs:comment "A large group of antibiotics isolated from various species of Streptomyces and characterised by having a substituted phenoxazine ring linked to two cyclic heterodetic peptides." ;
rdfs:subClassOf obo:CHEBI_23239 .
obo:PHIPO_0000478 a rdfs:Class ;
rdfs:label "lipid droplet phenotype"@en ;
rdfs:comment "A single organism phenotype that affects an intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins." ;
rdfs:subClassOf obo:PHIPO_0000415 .
obo:GO_0034642 a rdfs:Class ;
rdfs:label "mitochondrion migration along actin filament" ;
rdfs:comment "The directed movement of a mitochondrion along a microfilament, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0030048 , obo:GO_0046907 , obo:GO_0051654 , obo:GO_0099515 .
obo:UBERON_0004873 a rdfs:Class ;
rdfs:label "splanchnopleure" ;
rdfs:comment "A structure created during embryogenesis when the lateral mesoderm splits into two layers - the inner (or splanchnic) layer adheres to the endoderm, and with it forms the splanchnopleure[WP]." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0048869 a rdfs:Class ;
rdfs:label "cellular developmental process" ;
rdfs:comment "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0032502 .
obo:CL_0001024 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-negative hematopoietic stem cell" ;
rdfs:comment "CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive." ;
rdfs:subClassOf obo:CL_0000037 .
obo:GO_0006026 a rdfs:Class ;
rdfs:label "aminoglycan catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." ;
rdfs:subClassOf obo:GO_0006022 , obo:GO_0009056 , obo:GO_0009057 , obo:GO_1901136 .
obo:GO_1905808 a rdfs:Class ;
rdfs:label "positive regulation of synapse pruning" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of synapse pruning." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1905806 .
obo:GO_1905434 a rdfs:Class ;
rdfs:label "positive regulation of retrograde trans-synaptic signaling by neuropeptide" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." ;
rdfs:subClassOf obo:GO_0010647 , obo:GO_0023056 , obo:GO_0065007 , obo:GO_1905432 .
obo:UBERON_0001630 a rdfs:Class ;
rdfs:label "muscle organ" ;
rdfs:comment "Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0005090 .
obo:CHEBI_35441 a rdfs:Class ;
rdfs:label "antiinfective agent" ;
rdfs:comment "A substance used in the prophylaxis or therapy of infectious diseases." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0001705 a rdfs:Class ;
rdfs:label "ectoderm formation" ;
rdfs:comment "The formation of ectoderm during gastrulation." ;
rdfs:subClassOf obo:GO_0001704 , obo:GO_0048646 .
obo:UBERON_0004479 a rdfs:Class ;
rdfs:label "musculature of trunk" ;
rdfs:comment "Any collection of muscles that is part of a trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001015 .
obo:GO_0044283 a rdfs:Class ;
rdfs:label "small molecule biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0044281 .
obo:CHEBI_35560 a rdfs:Class ;
rdfs:label "1,2,4-triazole" ;
rdfs:subClassOf obo:CHEBI_38597 .
obo:PATO_0000586 a rdfs:Class ;
rdfs:label "increased size" ;
rdfs:comment "A size quality which is relatively high." ;
rdfs:subClassOf obo:PATO_0000117 , obo:PATO_0002305 .
obo:BFO_0000006 a rdfs:Class .
obo:GO_0042430 a rdfs:Class ;
rdfs:label "indole-containing compound metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." ;
rdfs:subClassOf obo:GO_0008152 .
obo:PHIPO_0001409 a rdfs:Class ;
rdfs:label "sensitive to iprovalicarb" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to iprovalicarb. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0046165 a rdfs:Class ;
rdfs:label "alcohol biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." ;
rdfs:subClassOf obo:GO_0006066 , obo:GO_0044283 .
obo:GO_0071554 a rdfs:Class ;
rdfs:label "cell wall organization or biogenesis" ;
rdfs:comment "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0045211 a rdfs:Class ;
rdfs:label "postsynaptic membrane" ;
rdfs:comment "A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane." ;
rdfs:subClassOf obo:GO_0097060 .
obo:PHIPO_0001021 a rdfs:Class ;
rdfs:label "sensitive to congo red"@en ;
rdfs:comment "A phenotype in which a population of a single-species shows increased sensitivity to congo red, manifested as an affect on the extent of population growth. (CHEBI:34653)." ;
rdfs:subClassOf obo:PHIPO_0000021 , obo:PHIPO_0001397 .
obo:UBERON_0004356 a rdfs:Class ;
rdfs:label "apical ectodermal ridge" ;
rdfs:comment "Multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:CL_0001032 a rdfs:Class ;
rdfs:label "cortical granule cell" ;
rdfs:comment "Granule cell that is part of the cerebral cortex." ;
rdfs:subClassOf obo:CL_0000120 , obo:CL_0010012 .
obo:GO_0030853 a rdfs:Class ;
rdfs:label "negative regulation of granulocyte differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation." ;
rdfs:subClassOf obo:GO_0002762 , obo:GO_0030852 , obo:GO_0065007 .
obo:GO_0002887 a rdfs:Class ;
rdfs:label "negative regulation of myeloid leukocyte mediated immunity" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity." ;
rdfs:subClassOf obo:GO_0002704 , obo:GO_0002886 , obo:GO_0065007 .
obo:CHEBI_52492 a rdfs:Class ;
rdfs:label "mancozeb" ;
rdfs:comment "A mixture composed from maneb and zineb, which is used as a broad-spectrum contact fungicide." ;
rdfs:subClassOf obo:CHEBI_60004 .
obo:UBERON_0001778 a rdfs:Class ;
rdfs:label "ciliary epithelium" ;
rdfs:comment "A double layer covering the ciliary body that produces aqueous humor." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0000488 , obo:UBERON_0015808 .
obo:GO_0048523 a rdfs:Class ;
rdfs:label "negative regulation of cellular process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0050794 , obo:GO_0065007 .
obo:PHIPO_0000495 a rdfs:Class ;
rdfs:label "secondary metabolite biosynthetic process phenotype"@en ;
rdfs:comment "A single organism phenotype that affects the chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." ;
rdfs:subClassOf obo:PHIPO_0000494 .
obo:GO_1904944 a rdfs:Class ;
rdfs:label "positive regulation of cardiac ventricle formation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901212 , obo:GO_1904942 .
obo:UBERON_0001652 a rdfs:Class ;
rdfs:label "left pulmonary artery" ;
rdfs:comment "The pulmonary artery that supplies the left lung." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:GO_1903804 a rdfs:Class ;
rdfs:label "glycine import across plasma membrane" ;
rdfs:comment "The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015816 , obo:GO_0089718 , obo:GO_1905039 .
obo:CHEBI_25512 a rdfs:Class ;
rdfs:label "neurotransmitter" ;
rdfs:comment "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." ;
rdfs:subClassOf obo:CHEBI_33280 .
obo:CHEBI_5530 a rdfs:Class ;
rdfs:label "gramicidin S" ;
rdfs:subClassOf obo:CHEBI_24613 , obo:CHEBI_25676 .
obo:CHEBI_36982 a rdfs:Class ;
rdfs:label "cyclic purine nucleotide" ;
rdfs:subClassOf obo:CHEBI_23447 , obo:CHEBI_26395 .
obo:CHEBI_474180 a rdfs:Class ;
rdfs:label "caspofungin" ;
rdfs:comment "A semisynthetic cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-β-D-glucan, an integral component of the fungal cell wall." ;
rdfs:subClassOf obo:CHEBI_24613 , obo:CHEBI_57248 , obo:CHEBI_72588 , obo:CHEBI_87113 .
obo:UBERON_0003886 a rdfs:Class ;
rdfs:label "future coelemic cavity lumen" ;
rdfs:comment "An anatomical cavity that has the potential to develop into a coelemic cavity lumen." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:RO_0002488 a rdf:Property ;
rdfs:label "existence starts during" ;
rdfs:comment "x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y)." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002496 , obo:RO_0002490 .
obo:CHEBI_74518 a rdfs:Class ;
rdfs:label "anti-obesity agent" ;
rdfs:comment "Any substance which is used to reduce or control weight." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:PHIPO_0000884 a rdfs:Class ;
rdfs:label "sensitive to cefazolin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefazolin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1903336 a rdfs:Class ;
rdfs:label "negative regulation of vacuolar transport" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0065007 , obo:GO_1903335 .
obo:CHEBI_61008 a rdfs:Class ;
rdfs:label "nitrogen-containing fatty acid anion" ;
rdfs:comment "A fatty acid anion arising from deprotonation of the carboxylic acid group of any nitrogen-containing fatty acid." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:CHEBI_83575 a rdfs:Class ;
rdfs:label "monofluorobenzenes" ;
rdfs:comment "Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying a single fluorine substitutent." ;
rdfs:subClassOf obo:CHEBI_35496 .
obo:GO_1901190 a rdfs:Class ;
rdfs:label "regulation of formation of translation initiation ternary complex" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0065007 .
obo:UBERON_0004040 a rdfs:Class ;
rdfs:label "cortical intermediate zone" ;
rdfs:comment "The region of the developing mammalian cortex that extends between the ventricular zone and the cortical plate (CP); normally, the IZ is a region of tangential migration of cells, and at midgestation, the lower part of the IZ develops into the subventricular zone." ;
rdfs:subClassOf obo:UBERON_0014950 .
obo:GO_0048736 a rdfs:Class ;
rdfs:label "appendage development" ;
rdfs:comment "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0010876 a rdfs:Class ;
rdfs:label "lipid localization" ;
rdfs:comment "Any process in which a lipid is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0033036 .
obo:GO_1905429 a rdfs:Class ;
rdfs:label "response to glycine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus." ;
rdfs:subClassOf obo:GO_0043200 , obo:GO_0050896 , obo:GO_1901698 , obo:GO_1901700 .
obo:UBERON_0000178 a rdfs:Class ;
rdfs:label "blood" ;
rdfs:comment "A fluid that is composed of blood plasma and erythrocytes." ;
rdfs:subClassOf obo:UBERON_0000061 , obo:UBERON_0000179 .
obo:CL_4307112 a rdfs:Class ;
rdfs:label "OEC NN_1 Rasgef1c olfactory ensheathing cell (Mmus)" ;
rdfs:comment "A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Mybpc1 (Mmus), Rasgef1c (Mmus). It is distinguished from other OEC cells by expression of Rasgef1c. It is glutamatergic (inferred from expression of Slc17a7). These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5292 OEC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000151 , obo:CL_4301615 .
obo:PHIPO_0000106 a rdfs:Class ;
rdfs:label "increased number of penetration structure"@en ;
rdfs:comment "A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration stuctures are increased when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000032 .
obo:UBERON_0001571 a rdfs:Class ;
rdfs:label "genioglossus muscle" ;
rdfs:comment "Either of a pair of lingual muscles with origin in the mandible, with insertion to the lingual fascia below the mucous membrane and epiglottis, with nerve supply from the hypoglossal nerve, and whose action depresses and protrudes the tongue." ;
rdfs:subClassOf obo:UBERON_0001575 , obo:UBERON_0004120 .
obo:RO_0002373 a rdf:Property ;
rdfs:label "has muscle insertion"@en ;
rdfs:comment "m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone."@en ;
rdfs:domain obo:UBERON_0000061 ;
rdfs:range obo:UBERON_0000061 ;
rdfs:subPropertyOf obo:RO_0002567 , obo:RO_0002371 .
obo:GO_1902816 a rdfs:Class ;
rdfs:label "regulation of protein localization to microtubule" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to microtubule." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_0010557 a rdfs:Class ;
rdfs:label "positive regulation of macromolecule biosynthetic process" ;
rdfs:comment "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0010556 , obo:GO_0010604 , obo:GO_0065007 .
obo:UBERON_0001048 a rdfs:Class ;
rdfs:label "primordium" ;
rdfs:comment "Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]." ;
rdfs:subClassOf obo:UBERON_0005423 .
obo:GO_0061323 a rdfs:Class ;
rdfs:label "cell proliferation involved in heart morphogenesis" ;
rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart." ;
rdfs:subClassOf obo:GO_0008283 .
obo:CHEBI_39745 a rdfs:Class ;
rdfs:label "dihydrogenphosphate" ;
rdfs:comment "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." ;
rdfs:subClassOf obo:CHEBI_35780 , obo:CHEBI_79389 .
obo:GO_2000353 a rdfs:Class ;
rdfs:label "positive regulation of endothelial cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0065007 , obo:GO_2000351 .
obo:GO_0007440 a rdfs:Class ;
rdfs:label "foregut morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the foregut are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0002683 a rdfs:Class ;
rdfs:label "negative regulation of immune system process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0048519 , obo:GO_0065007 .
obo:GO_0120261 a rdfs:Class ;
rdfs:label "regulation of heterochromatin organization" ;
rdfs:comment "Any process that modulates the frequency, rate, extent or location of heterochromatin organization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902275 .
obo:PHIPO_0000144 a rdfs:Class ;
rdfs:label "normal protein complex binding"@en ;
rdfs:comment "A single species molecular function phenotype in which the binding of one protein to a protein complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the protein complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000134 .
obo:UBERON_0009122 a rdfs:Class ;
rdfs:label "adenohypophyseal placode" ;
rdfs:comment "The adenohypophyseal placode forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary." ;
rdfs:subClassOf obo:UBERON_0002546 , obo:UBERON_0011814 .
obo:UBERON_0008001 a rdfs:Class ;
rdfs:label "irregular bone" ;
rdfs:comment "The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid." ;
rdfs:subClassOf obo:UBERON_0001474 .
obo:GO_0030990 a rdfs:Class ;
rdfs:label "intraciliary transport particle" ;
rdfs:comment "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." ;
rdfs:subClassOf obo:GO_0032991 .
obo:CL_0002543 a rdfs:Class ;
rdfs:label "vein endothelial cell" ;
rdfs:comment "An endothelial cell that is part of the vein." ;
rdfs:subClassOf obo:CL_0000071 .
obo:CL_0008042 a rdfs:Class ;
rdfs:label "tanycyte of subfornical organ" ;
rdfs:comment "A tanycyte of the subfornical organ (SFO). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SFO, where they form a dense network surrounding these capillaries." ;
rdfs:subClassOf obo:CL_0002085 .
obo:CL_0000827 a rdfs:Class ;
rdfs:label "pro-T cell" ;
rdfs:comment "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." ;
rdfs:subClassOf obo:CL_0000838 .
obo:CHEBI_35703 a rdfs:Class ;
rdfs:label "xenobiotic" ;
rdfs:comment "A xenobiotic (Greek, xenos \"foreign\"; bios \"life\") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:GO_0061156 a rdfs:Class ;
rdfs:label "pulmonary artery morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048844 .
obo:PHIPO_0000650 a rdfs:Class ;
rdfs:label "resistance to ertapenem"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ertapenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000693 .
obo:GO_0046888 a rdfs:Class ;
rdfs:label "negative regulation of hormone secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell." ;
rdfs:subClassOf obo:GO_0010648 , obo:GO_0023057 , obo:GO_0046883 , obo:GO_0065007 , obo:GO_1903531 .
obo:CHEBI_15940 a rdfs:Class ;
rdfs:label "nicotinic acid" ;
rdfs:comment "A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group." ;
rdfs:subClassOf obo:CHEBI_176839 , obo:CHEBI_26416 , obo:CHEBI_26420 .
obo:UBERON_0000026 a rdfs:Class ;
rdfs:label "appendage" ;
rdfs:comment "Major subdivision of an organism that protrudes from the body[DOS, CARO]." ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:CHEBI_77715 a rdfs:Class ;
rdfs:label "nasal decongestant" ;
rdfs:comment "A drug used to relieve nasal congestion in the upper respiratory tract." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:UBERON_0006211 a rdfs:Class ;
rdfs:label "buccopharyngeal membrane" ;
rdfs:comment "The thin bilaminar membrane derived from the prechordal plate that is devoid of mesoderm and formed by the apposition of the stomodeal ectoderm with the foregut endoderm; after the embryonic head fold has evolved it lies at the caudal limit of the stomodeum, forming a septum between the primitive mouth and pharynx; the membrane eventually disappears, and thus a communication is established between the mouth and the future pharynx." ;
rdfs:subClassOf obo:UBERON_0003037 .
obo:GO_0043062 a rdfs:Class ;
rdfs:label "extracellular structure organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite." ;
rdfs:subClassOf obo:GO_0016043 .
obo:UBERON_0003714 a rdfs:Class ;
rdfs:label "neural tissue" ;
rdfs:comment "Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:GO_2001214 a rdfs:Class ;
rdfs:label "positive regulation of vasculogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vasculogenesis." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0065007 , obo:GO_2001212 .
obo:GO_0007586 a rdfs:Class ;
rdfs:label "digestion" ;
rdfs:comment "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0032501 .
obo:CHEBI_48901 a rdfs:Class ;
rdfs:label "thiazoles" ;
rdfs:comment "An azole in which the five-membered heterocyclic aromatic skeleton contains a N atom and one S atom." ;
rdfs:subClassOf obo:CHEBI_38106 , obo:CHEBI_68452 .
obo:UBERON_0001972 a rdfs:Class ;
rdfs:label "submucosa of esophagus" ;
rdfs:comment "A submucosa that is part of a esophagus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000009 , obo:UBERON_0018257 .
obo:BSPO_0001107 a rdf:Property ;
rdfs:range .
obo:CL_0000778 a rdfs:Class ;
rdfs:label "mononuclear osteoclast" ;
rdfs:comment "A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts." ;
rdfs:subClassOf obo:CL_0000092 , obo:CL_0000113 .
obo:CHEBI_62488 a rdfs:Class ;
rdfs:label "signalling molecule" ;
rdfs:comment "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell." ;
rdfs:subClassOf obo:CHEBI_33280 .
obo:GO_0045637 a rdfs:Class ;
rdfs:label "regulation of myeloid cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of myeloid cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903706 .
obo:GO_0051151 a rdfs:Class ;
rdfs:label "negative regulation of smooth muscle cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051148 , obo:GO_0051150 , obo:GO_0065007 .
obo:CL_0010004 a rdfs:Class ;
rdfs:label "mononuclear cell of bone marrow" ;
rdfs:comment "A mononuclear cell that is part_of a bone marrow." ;
rdfs:subClassOf obo:CL_0000842 , obo:CL_1001610 .
obo:PR_000001666 a rdfs:Class ;
rdfs:label "relaxin receptor 1" ;
rdfs:comment "A relaxin family peptide receptor protein that is a translation product of the human RXFP1 gene or a 1:1 ortholog thereof. This receptor is expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart." ;
rdfs:subClassOf obo:PR_000001551 .
obo:UBERON_0003619 a rdfs:Class ;
rdfs:label "aorta tunica intima" ;
rdfs:comment "The innermost layer of the aorta, containing the endothelium and an inner elastic membrane." ;
rdfs:subClassOf obo:UBERON_0002523 , obo:UBERON_0004797 .
obo:CHEBI_35480 a rdfs:Class ;
rdfs:label "analgesic" ;
rdfs:comment "An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_52210 .
obo:UBERON_0005734 a rdfs:Class ;
rdfs:label "tunica adventitia of blood vessel" ;
rdfs:comment "The outermost layer of a blood vessel, composed mainly of fibrous tissue." ;
rdfs:subClassOf obo:UBERON_0004797 , obo:UBERON_0005742 .
obo:GO_0021607 a rdfs:Class ;
rdfs:label "accessory nerve morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0021602 .
obo:GO_0045651 a rdfs:Class ;
rdfs:label "positive regulation of macrophage differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of macrophage differentiation." ;
rdfs:subClassOf obo:GO_0002763 , obo:GO_0045649 , obo:GO_0065007 .
obo:UBERON_0002314 a rdfs:Class ;
rdfs:label "midbrain tectum" ;
rdfs:comment "Dorsal part of the midbrain, consisting of the superior and inferior colliculi and the pretectal nuclei (MM)." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_0008016 a rdfs:Class ;
rdfs:label "regulation of heart contraction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903522 .
obo:CL_4301590 a rdfs:Class ;
rdfs:label "Astro-NT NN_2 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Itih3 (Mmus), Gria2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1160 Astro-NT NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300358 .
obo:GO_0048639 a rdfs:Class ;
rdfs:label "positive regulation of developmental growth" ;
rdfs:comment "Any process that activates, maintains or increases the rate of developmental growth." ;
rdfs:subClassOf obo:GO_0045927 , obo:GO_0048638 , obo:GO_0051094 , obo:GO_0065007 .
obo:GO_0071868 a rdfs:Class ;
rdfs:label "cellular response to monoamine stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_0071867 , obo:GO_1901699 .
obo:GO_0098691 a rdfs:Class ;
rdfs:label "dopaminergic synapse" ;
rdfs:comment "A synapse that uses dopamine as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0045202 .
obo:GO_0061558 a rdfs:Class ;
rdfs:label "cranial ganglion maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0061553 , obo:GO_0071695 .
obo:CHEBI_16199 a rdfs:Class ;
rdfs:label "urea" ;
rdfs:comment "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O)." ;
rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_64708 .
obo:CHEBI_38338 a rdfs:Class ;
rdfs:label "aminopyrimidine" ;
rdfs:comment "A member of the class of pyrimidines that is pyrimidine substituted by at least one amino group and its derivatives." ;
rdfs:subClassOf obo:CHEBI_33860 , obo:CHEBI_39447 .
obo:UBERON_0002057 a rdfs:Class ;
rdfs:label "phrenic artery" ;
rdfs:comment "An artery that supplies the diaphragm." ;
rdfs:subClassOf obo:UBERON_0004573 .
obo:CL_4307031 a rdfs:Class ;
rdfs:label "Astro-NT NN_1 Six3os1 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Six3os1 (Mmus), Slc36a2 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Six3os1. These cells are located in the Striatum-like amygdalar nuclei, Olfactory areas, brain , in or close to the regions: Medial amygdalar nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5211 Astro-NT NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301589 .
obo:UBERON_0010740 a rdfs:Class ;
rdfs:label "bone of appendage girdle complex" ;
rdfs:comment "A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle)." ;
rdfs:subClassOf obo:UBERON_0001474 .
obo:UBERON_0000043 a rdfs:Class ;
rdfs:label "tendon" ;
rdfs:comment "Dense regular connective tissue that connects muscle to bone[VSAO]." ;
rdfs:subClassOf obo:UBERON_0007846 .
obo:GO_0001838 a rdfs:Class ;
rdfs:label "embryonic epithelial tube formation" ;
rdfs:comment "The morphogenesis of an embryonic epithelium into a tube-shaped structure." ;
rdfs:subClassOf obo:GO_0072175 .
obo:GO_0050672 a rdfs:Class ;
rdfs:label "negative regulation of lymphocyte proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation." ;
rdfs:subClassOf obo:GO_0032945 , obo:GO_0050670 , obo:GO_0051250 , obo:GO_0065007 .
obo:GO_0009902 a rdfs:Class ;
rdfs:label "chloroplast relocation" ;
rdfs:comment "The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery." ;
rdfs:subClassOf obo:GO_0009658 , obo:GO_0019750 , obo:GO_0051234 , obo:GO_0051667 .
obo:PHIPO_0001359 a rdfs:Class ;
rdfs:label "resistance to kresoxim-methyl" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to kresoxim-methyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_33842 a rdfs:Class ;
rdfs:label "aromatic annulene" ;
rdfs:subClassOf obo:CHEBI_33662 , obo:CHEBI_33847 .
obo:GO_0090130 a rdfs:Class ;
rdfs:label "tissue migration" ;
rdfs:comment "The process in which the population of cells that make up a tissue undergo directed movement." ;
rdfs:subClassOf obo:GO_0032501 .
obo:CL_0000064 a rdfs:Class ;
rdfs:label "ciliated cell" ;
rdfs:comment "A cell that has a filiform extrusion of the cell surface." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_0060127 a rdfs:Class ;
rdfs:label "prolactin secreting cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin." ;
rdfs:subClassOf obo:GO_0030154 .
obo:UBERON_0004732 a rdfs:Class ;
rdfs:label "segmental subdivision of nervous system" ;
rdfs:comment "Any segmental subdivision of a nervous system. Includes metameric developmental segments, such as vertebrates neuromeres." ;
rdfs:subClassOf obo:UBERON_0000063 .
obo:UBERON_0009610 a rdfs:Class ;
rdfs:label "forebrain neural plate" ;
rdfs:comment "A neural plate that develops_from a future forebrain." ;
rdfs:subClassOf obo:UBERON_0003075 .
obo:CL_0009097 a rdfs:Class ;
rdfs:label "embryonic skeletal muscle fiber" ;
rdfs:comment "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development." ;
rdfs:subClassOf obo:CL_0008002 .
obo:RO_0002491 a rdf:Property ;
rdfs:label "existence starts and ends during" ;
rdfs:comment "x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y)" ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002492 , obo:RO_0002488 .
obo:GO_0045595 a rdfs:Class ;
rdfs:label "regulation of cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0050794 , obo:GO_0065007 .
obo:CHEBI_47724 a rdfs:Class ;
rdfs:label "vancomycin aglycone" ;
rdfs:comment "A peptide antibiotic that is vancomycin lacking the disaccharide moiety." ;
rdfs:subClassOf obo:CHEBI_24533 , obo:CHEBI_25903 , obo:CHEBI_26195 , obo:CHEBI_37407 .
obo:CHEBI_64250 a rdfs:Class ;
rdfs:label "tunicamycin B2" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 13-methyltetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:CHEBI_9665 a rdfs:Class ;
rdfs:label "triadimefon" ;
rdfs:comment "A racemate comprising equal amounts of (R)- and (S)-triadimefon. A fungicide used to control powdery mildew, rusts and other infections in crops." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87067 , obo:CHEBI_87100 .
obo:CHEBI_52440 a rdfs:Class ;
rdfs:label "cephalosporin carboxylic acid anion" ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:CHEBI_22713 a rdfs:Class ;
rdfs:label "arenesulfonate oxoanion" ;
rdfs:subClassOf obo:CHEBI_33554 .
obo:GO_0042428 a rdfs:Class ;
rdfs:label "serotonin metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0018958 , obo:GO_0042430 .
obo:CHEBI_26191 a rdfs:Class ;
rdfs:label "polyol" ;
rdfs:comment "A compound that contains two or more hydroxy groups." ;
rdfs:subClassOf obo:CHEBI_33822 .
obo:UBERON_0014532 a rdfs:Class ;
rdfs:label "white matter lamina of cerebral hemisphere" ;
rdfs:subClassOf obo:UBERON_0014530 .
obo:UBERON_0003618 a rdfs:Class ;
rdfs:label "aorta tunica media" ;
rdfs:comment "The middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers." ;
rdfs:subClassOf obo:UBERON_0002522 .
obo:GO_0150052 a rdfs:Class ;
rdfs:label "regulation of postsynapse assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse." ;
rdfs:subClassOf obo:GO_0051963 , obo:GO_0065007 , obo:GO_0099175 .
obo:CHEBI_138856 a rdfs:Class ;
rdfs:label "oxolinic acid" ;
rdfs:comment "A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry." ;
rdfs:subClassOf obo:CHEBI_26512 , obo:CHEBI_26979 , obo:CHEBI_38104 , obo:CHEBI_86324 .
obo:GO_0002318 a rdfs:Class ;
rdfs:label "myeloid progenitor cell differentiation" ;
rdfs:comment "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages." ;
rdfs:subClassOf obo:GO_0002244 , obo:GO_0030154 .
obo:UBERON_0004663 a rdfs:Class ;
rdfs:label "aorta wall" ;
rdfs:comment "An anatomical wall that is part of an aorta, enclosing the luminal space." ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0035965 .
obo:PR_000001199 a rdfs:Class ;
rdfs:label "C-C chemokine receptor type 2" ;
rdfs:comment "A chemokine receptor that is a translation product of the human CCR2 gene or a 1:1 ortholog thereof. The preferred ligands include CCL2, CCL7, CCL8, CCL13." ;
rdfs:subClassOf obo:PR_000001128 .
obo:UBERON_0007188 a rdfs:Class ;
rdfs:label "mesothelium of serous pericardium" ;
rdfs:comment "A mesothelium that is part of a serous pericardium." ;
rdfs:subClassOf obo:UBERON_0001136 , obo:UBERON_0003388 .
obo:GO_0005173 a rdfs:Class ;
rdfs:label "stem cell factor receptor binding" ;
rdfs:comment "Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor." ;
rdfs:subClassOf obo:GO_0005126 , obo:GO_0005488 .
obo:UBERON_0011134 a rdfs:Class ;
rdfs:label "nonsynovial joint" ;
rdfs:comment "Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis." ;
rdfs:subClassOf obo:UBERON_0000982 .
obo:UBERON_0001359 a rdfs:Class ;
rdfs:label "cerebrospinal fluid" ;
rdfs:comment "A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord." ;
rdfs:subClassOf obo:UBERON_0007779 .
obo:GO_1903045 a rdfs:Class ;
rdfs:label "neural crest cell migration involved in sympathetic nervous system development" ;
rdfs:comment "Any neural crest cell migration that is involved in sympathetic nervous system development." ;
rdfs:subClassOf obo:GO_0001755 , obo:GO_1901166 .
obo:CHEBI_22315 a rdfs:Class ;
rdfs:label "alkaloid" ;
rdfs:comment "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:CL_4301571 a rdfs:Class ;
rdfs:label "DCO Il22 Gly-Gaba_1 cerebellar neuron (Mmus)" ;
rdfs:comment "A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Il22 (Mmus), Rftn1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1141 DCO Il22 Gly-Gaba_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300348 .
obo:GO_2001054 a rdfs:Class ;
rdfs:label "negative regulation of mesenchymal cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0065007 , obo:GO_2001053 .
obo:GO_0001674 a rdfs:Class ;
rdfs:label "female germ cell nucleus" ;
rdfs:comment "The nucleus of the female germ cell, a reproductive cell in females." ;
rdfs:subClassOf obo:GO_0005634 , obo:GO_0043073 .
obo:GO_1902256 a rdfs:Class ;
rdfs:label "regulation of apoptotic process involved in outflow tract morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904748 .
obo:CHEBI_25389 a rdfs:Class ;
rdfs:label "monohydroxybenzoic acid" ;
rdfs:comment "Any hydroxybenzoic acid having a single phenolic hydroxy substituent on the benzene ring." ;
rdfs:subClassOf obo:CHEBI_24676 .
obo:CHEBI_33482 a rdfs:Class ;
rdfs:label "sulfur oxoanion" ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_33485 .
obo:GO_2000111 a rdfs:Class ;
rdfs:label "positive regulation of macrophage apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process." ;
rdfs:subClassOf obo:GO_0033034 , obo:GO_0065007 , obo:GO_2000108 , obo:GO_2000109 .
obo:GO_0048584 a rdfs:Class ;
rdfs:label "positive regulation of response to stimulus" ;
rdfs:comment "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0048583 , obo:GO_0065007 .
obo:GO_0002790 a rdfs:Class ;
rdfs:label "peptide secretion" ;
rdfs:comment "The controlled release of a peptide from a cell or a tissue." ;
rdfs:subClassOf obo:GO_0015833 , obo:GO_0046903 .
obo:GO_0051955 a rdfs:Class ;
rdfs:label "regulation of amino acid transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051952 , obo:GO_0065007 .
obo:GO_0006468 a rdfs:Class ;
rdfs:label "protein phosphorylation" ;
rdfs:comment "The process of introducing a phosphate group on to a protein." ;
rdfs:subClassOf obo:GO_0016310 , obo:GO_0036211 .
a rdfs:Class ;
rdfs:label "GRP" ;
rdfs:subClassOf obo:SO_0000704 .
obo:UBERON_0003953 a rdfs:Class ;
rdfs:label "posterior stroma of cornea" ;
rdfs:comment "The posterior segment of the lamellated connective tissue layer of the cornea." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003566 .
obo:BSPO_0000122 a rdf:Property ;
rdfs:range .
obo:GO_0048194 a rdfs:Class ;
rdfs:label "Golgi vesicle budding" ;
rdfs:comment "The evagination of the Golgi membrane, resulting in formation of a vesicle." ;
rdfs:subClassOf obo:GO_0006900 .
obo:CHEBI_82891 a rdfs:Class ;
rdfs:label "glucocorticoid receptor antagonist" ;
rdfs:comment "An antagonist that binds to and deactivates glucocorticoid receptors." ;
rdfs:subClassOf obo:CHEBI_48706 .
a rdfs:Class ;
rdfs:label "Hypoglossal nucleus" ;
rdfs:subClassOf , obo:UBERON_0002871 .
obo:CHEBI_6076 a rdfs:Class ;
rdfs:label "itraconazole" ;
rdfs:comment "An N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(±)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis." ;
rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_35618 , obo:CHEBI_39430 , obo:CHEBI_46848 , obo:CHEBI_59779 , obo:CHEBI_60911 , obo:CHEBI_87071 , obo:CHEBI_87101 .
obo:GO_0048311 a rdfs:Class ;
rdfs:label "mitochondrion distribution" ;
rdfs:comment "Any process that establishes the spatial arrangement of mitochondria between and within cells." ;
rdfs:subClassOf obo:GO_0051646 .
obo:CL_4301586 a rdfs:Class ;
rdfs:label "unipolar brush cell (Mmus)" ;
rdfs:comment "A unipolar brush cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Sln (Mmus), Lmx1a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1156 DCO UBC Glut_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4023161 , obo:CL_4300029 .
obo:GO_0010719 a rdfs:Class ;
rdfs:label "negative regulation of epithelial to mesenchymal transition" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." ;
rdfs:subClassOf obo:GO_0010717 , obo:GO_0045596 , obo:GO_0051241 , obo:GO_0065007 .
obo:GO_1902840 a rdfs:Class ;
rdfs:label "positive regulation of nuclear migration along microtubule" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0065007 , obo:GO_1902838 .
obo:GO_0055026 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle tissue development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development." ;
rdfs:subClassOf obo:GO_0045843 , obo:GO_0055024 , obo:GO_0065007 .
obo:GO_1904697 a rdfs:Class ;
rdfs:label "regulation of acinar cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of acinar cell proliferation." ;
rdfs:subClassOf obo:GO_0050678 , obo:GO_0065007 .
obo:GO_2000527 a rdfs:Class ;
rdfs:label "regulation of myeloid dendritic cell chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000508 .
obo:UBERON_0003311 a rdfs:Class ;
rdfs:label "floor plate of medulla oblongata" ;
rdfs:comment "A floor plate that is part of a medulla oblongata [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0002616 , obo:UBERON_0003306 .
obo:CHEBI_64383 a rdfs:Class ;
rdfs:label "pentamidinium(2+)" ;
rdfs:comment "A carboxamidinium ion obtained by protonation of both amindino groups of pentamidine." ;
rdfs:subClassOf obo:CHEBI_77718 .
obo:PHIPO_0000295 a rdfs:Class ;
rdfs:label "sinusoidal filament"@en ;
rdfs:comment "A single species cell morphology phenotype where hyphal filaments are wavy." ;
rdfs:subClassOf obo:PHIPO_0001205 .
obo:CHEBI_73474 a rdfs:Class ;
rdfs:label "acetylenic compound" ;
rdfs:comment "Any organic molecule containing a C≡C bond." ;
rdfs:subClassOf obo:CHEBI_72695 .
obo:PATO_0001018 a rdfs:Class ;
rdfs:label "physical quality" ;
rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:CHEBI_25605 a rdfs:Class ;
rdfs:label "nucleoside antibiotic" ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:GO_0022884 a rdfs:Class ;
rdfs:label "macromolecule transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of a macromolecule from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 .
obo:GO_0035702 a rdfs:Class ;
rdfs:label "monocyte homeostasis" ;
rdfs:comment "The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." ;
rdfs:subClassOf obo:GO_0001776 , obo:GO_0002262 , obo:GO_0048872 .
obo:PHIPO_0000969 a rdfs:Class ;
rdfs:label "present pathogen growth after penetration of the barrier"@en ;
rdfs:comment "A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is present." ;
rdfs:subClassOf obo:PHIPO_0000027 .
obo:PR_P35456 a rdfs:Class ;
rdfs:label "urokinase plasminogen activator surface receptor (mouse)" ;
rdfs:comment "A urokinase plasminogen activator surface receptor that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001969 , obo:PR_000029032 .
obo:GO_0021580 a rdfs:Class ;
rdfs:label "medulla oblongata formation" ;
rdfs:comment "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0045446 a rdfs:Class ;
rdfs:label "endothelial cell differentiation" ;
rdfs:comment "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030855 .
obo:GO_0014008 a rdfs:Class ;
rdfs:label "positive regulation of microglia differentiation" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell." ;
rdfs:subClassOf obo:GO_0014006 , obo:GO_0045651 , obo:GO_0045687 , obo:GO_0065007 .
obo:GO_2001037 a rdfs:Class ;
rdfs:label "positive regulation of tongue muscle cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902811 , obo:GO_2001035 .
obo:GO_0014047 a rdfs:Class ;
rdfs:label "glutamate secretion" ;
rdfs:comment "The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system." ;
rdfs:subClassOf obo:GO_0006835 , obo:GO_0015800 , obo:GO_0032940 , obo:GO_0046903 , obo:GO_0071705 .
obo:PATO_0001309 a rdfs:Class ;
rdfs:label "duration" ;
rdfs:comment "A process quality inhering in a bearer by virtue of the bearer's magnitude of the temporal extent between the starting and ending point." ;
rdfs:subClassOf obo:PATO_0002062 .
obo:GO_0007034 a rdfs:Class ;
rdfs:label "vacuolar transport" ;
rdfs:comment "The directed movement of substances into, out of or within a vacuole." ;
rdfs:subClassOf obo:GO_0046907 .
obo:CHEBI_42355 a rdfs:Class ;
rdfs:label "erythromycin A" ;
rdfs:comment "An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively." ;
rdfs:subClassOf obo:CHEBI_3992 , obo:CHEBI_48923 .
obo:GO_0033059 a rdfs:Class ;
rdfs:label "cellular pigmentation" ;
rdfs:comment "The deposition or aggregation of coloring matter in a cell." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0043473 .
obo:CHEBI_33695 a rdfs:Class ;
rdfs:label "information biomacromolecule" ;
rdfs:subClassOf obo:CHEBI_33694 .
obo:GO_0051590 a rdfs:Class ;
rdfs:label "positive regulation of neurotransmitter transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051050 , obo:GO_0051588 , obo:GO_0065007 .
obo:UBERON_0016879 a rdfs:Class ;
rdfs:label "future central nervous system" ;
rdfs:comment "Primordium that develops into the central nervous system." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:UBERON_0001894 a rdfs:Class ;
rdfs:label "diencephalon" ;
rdfs:comment "The division of the forebrain that develops from the foremost primary cerebral vesicle." ;
rdfs:subClassOf obo:UBERON_0002616 , obo:UBERON_0004121 , obo:UBERON_0010314 .
obo:PATO_0070045 a rdfs:Class ;
rdfs:label "anatomical histological quality" ;
rdfs:comment "A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes." ;
rdfs:subClassOf obo:PATO_0070044 .
obo:CL_0000349 a rdfs:Class ;
rdfs:label "extraembryonic cell" ;
rdfs:comment "Any cell that is part of some extraembryonic structure." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:UBERON_0015165 a rdfs:Class ;
rdfs:label "multi-unit eye" ;
rdfs:comment "An eye consisting of multiple light-sensing organs." ;
rdfs:subClassOf obo:UBERON_0000970 .
obo:UBERON_0007196 a rdfs:Class ;
rdfs:label "tracheobronchial tree" ;
rdfs:comment "The structure from the trachea, bronchi, and bronchioles that forms the airways that supply air to the lungs. The lining of the tracheobronchial tree consists of ciliated columnar epithelial cells." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:GO_0030186 a rdfs:Class ;
rdfs:label "melatonin metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine)." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0042430 , obo:GO_0042445 .
obo:UBERON_0035159 a rdfs:Class ;
rdfs:label "entire surface of organism" ;
rdfs:comment "Anatomical surface, which is the external surface of the whole body. Examples: There is only one body surface." ;
rdfs:subClassOf obo:UBERON_0006984 .
obo:CL_4300354 a rdfs:Class ;
rdfs:label "cerebellar granule cell (Mmus)" ;
rdfs:comment "A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Ror1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:314 CB Granule Glut." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0001031 , obo:CL_4300029 .
obo:PHIPO_0001399 a rdfs:Class ;
rdfs:label "resistance to flusilazole" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to flusilazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0001070 a rdfs:Class ;
rdfs:label "external carotid artery" ;
rdfs:comment "A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]." ;
rdfs:subClassOf obo:UBERON_0005396 .
obo:GO_0043073 a rdfs:Class ;
rdfs:label "germ cell nucleus" ;
rdfs:comment "The nucleus of a germ cell, a reproductive cell in multicellular organisms." ;
rdfs:subClassOf obo:GO_0005634 .
obo:GO_0034329 a rdfs:Class ;
rdfs:label "cell junction assembly" ;
rdfs:comment "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0034330 .
obo:CHEBI_17790 a rdfs:Class ;
rdfs:label "methanol" ;
rdfs:comment "The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group." ;
rdfs:subClassOf obo:CHEBI_134179 , obo:CHEBI_15734 , obo:CHEBI_26191 , obo:CHEBI_50584 , obo:CHEBI_64708 .
obo:GO_1905386 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to presynapse" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to presynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902474 , obo:GO_1905384 .
obo:UBERON_0000110 a rdfs:Class ;
rdfs:label "neurula stage" ;
rdfs:comment "A chordate developmental stage defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:RO_0002082 a rdf:Property ;
rdfs:label "simultaneous with"@en ;
rdfs:comment "x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002081 .
obo:GO_0140242 a rdfs:Class ;
rdfs:label "translation at postsynapse" ;
rdfs:comment "Translation that occurs at the postsynapse." ;
rdfs:subClassOf obo:GO_0006412 , obo:GO_0140241 .
obo:CHEBI_76712 a rdfs:Class ;
rdfs:label "EC 4.2.* (C-O lyase) inhibitor" ;
rdfs:comment "A lyase inhibitor which inhibits the action of a C‒O lyase (EC 4.2.*.*)." ;
rdfs:subClassOf obo:CHEBI_76710 .
obo:PATO_0001396 a rdfs:Class ;
rdfs:label "cellular quality" ;
rdfs:comment "A monadic quality of continuant that exists at the cellular level of organisation." ;
rdfs:subClassOf obo:PATO_0070044 .
obo:UBERON_0009602 a rdfs:Class ;
rdfs:label "left lung associated mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a developing left lung." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0004883 .
obo:CL_0000637 a rdfs:Class ;
rdfs:label "chromophil cell of anterior pituitary gland" ;
rdfs:comment "A cell that stains readily in the anterior pituitary gland." ;
rdfs:subClassOf obo:CL_0000150 , obo:CL_0000166 , obo:CL_0000167 , obo:CL_0012001 , obo:CL_2000004 .
obo:CHEBI_46952 a rdfs:Class ;
rdfs:label "oxazinane" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 , obo:CHEBI_38104 .
obo:GO_0002718 a rdfs:Class ;
rdfs:label "regulation of cytokine production involved in immune response" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response." ;
rdfs:subClassOf obo:GO_0001817 , obo:GO_0002700 , obo:GO_0065007 .
obo:CHEBI_37176 a rdfs:Class ;
rdfs:label "mononuclear parent hydride" ;
rdfs:subClassOf obo:CHEBI_33692 .
obo:CHEBI_146260 a rdfs:Class ;
rdfs:label "spectinomycin(1+)" ;
rdfs:comment "A secondary ammonium ion derived from spectinomycin by protonation of the secondary amino group located between the two alcoholic hydroxy groups." ;
rdfs:subClassOf obo:CHEBI_137419 .
obo:GO_1905952 a rdfs:Class ;
rdfs:label "regulation of lipid localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lipid localization." ;
rdfs:subClassOf obo:GO_0032879 , obo:GO_0065007 .
obo:UBERON_0005689 a rdfs:Class ;
rdfs:label "2nd arch mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a pharyngeal arch 2." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0009494 .
obo:UBERON_0003056 a rdfs:Class ;
rdfs:label "pre-chordal neural plate" ;
rdfs:comment "The portion of neural plate anterior to the mid-hindbrain junction." ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:CL_0000447 a rdfs:Class ;
rdfs:label "carbohydrate secreting cell" ;
rdfs:subClassOf obo:CL_0000151 .
obo:CHEBI_33595 a rdfs:Class ;
rdfs:label "cyclic compound" ;
rdfs:comment "Any molecule that consists of a series of atoms joined together to form a ring." ;
rdfs:subClassOf obo:CHEBI_25367 .
obo:CL_4307051 a rdfs:Class ;
rdfs:label "Astro-OLF NN_1 Greb1 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Chrdl1 (Mmus), Ano1 (Mmus), Il33 (Mmus). It is distinguished from other Astro-OLF NN_1 cells by expression of Greb1, Il33. These cells are located in the Olfactory areas, brain , in or close to the regions: Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5231 Astro-OLF NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301596 .
obo:GO_0005741 a rdfs:Class ;
rdfs:label "mitochondrial outer membrane" ;
rdfs:comment "The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031966 , obo:GO_0031968 .
obo:CL_0000098 a rdfs:Class ;
rdfs:label "sensory epithelial cell" ;
rdfs:comment "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0000197 .
obo:GO_0051129 a rdfs:Class ;
rdfs:label "negative regulation of cellular component organization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0051152 a rdfs:Class ;
rdfs:label "positive regulation of smooth muscle cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051149 , obo:GO_0051150 , obo:GO_0065007 .
obo:CL_0020008 a rdfs:Class ;
rdfs:label "striatal cholinergic-GABAergic neuron" ;
rdfs:comment "A large aspiny interneuron of the striatum that serves as the principal intrinsic source of acetylcholine while simultaneously releasing GABA. It is defined by coexpression of cholinergic markers (ChAT and VAChT/Slc18a3) and GABAergic markers (GAD65/Gad2 and VGAT/Slc32a1) (Lozovaya et al., 2018). This MGE-derived neuron maintains Lhx6 expression associated with dual-transmitter identity (Fragkouli et al., 2009; Marin et al., 2000). Morphologically, it possesses a large soma (20–50 μm diameter), 2–4 thick aspiny dendrites extending radially ~1 mm, and locally ramified axons with hundreds of thousands of varicosities (Wilson et al., 1990; Lim et al., 2014)." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_0008061 , obo:CL_0011005 .
obo:GO_0097475 a rdfs:Class ;
rdfs:label "motor neuron migration" ;
rdfs:comment "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." ;
rdfs:subClassOf obo:GO_0001764 , obo:GO_0016477 .
obo:GO_0035927 a rdfs:Class ;
rdfs:label "RNA import into mitochondrion" ;
rdfs:comment "The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0010496 , obo:GO_0050658 , obo:GO_0055085 .
obo:GO_0031981 a rdfs:Class ;
rdfs:label "nuclear lumen" ;
rdfs:comment "The volume enclosed by the nuclear inner membrane." ;
rdfs:subClassOf obo:GO_0070013 .
obo:UBERON_0012075 a rdfs:Class ;
rdfs:label "replacement bone" ;
rdfs:comment "Bone that forms as a replacement of another structural tissue." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0010522 .
obo:PHIPO_0000436 a rdfs:Class ;
rdfs:label "decreased catalytic activity"@en ;
rdfs:comment "A single species molecular function phenotype in which the observed rate of a specified catalytic activity is decreased." ;
rdfs:subClassOf obo:PHIPO_0000434 .
obo:GO_1902875 a rdfs:Class ;
rdfs:label "regulation of embryonic pattern specification" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of embryonic pattern specification." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 .
obo:UBERON_0007280 a rdfs:Class ;
rdfs:label "presumptive endocardium" ;
rdfs:comment "A presumptive structure that has the potential to develop into a endocardium." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:UBERON_0016513 a rdfs:Class ;
rdfs:label "cavity of left atrium" ;
rdfs:comment "Luminal space of the left atrium of the heart." ;
rdfs:subClassOf obo:UBERON_0002553 , obo:UBERON_0035763 .
obo:GO_0001507 a rdfs:Class ;
rdfs:label "acetylcholine catabolic process in synaptic cleft" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission." ;
rdfs:subClassOf obo:GO_0006581 .
obo:GO_0070665 a rdfs:Class ;
rdfs:label "positive regulation of leukocyte proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0065007 , obo:GO_0070663 .
obo:GO_0071425 a rdfs:Class ;
rdfs:label "hematopoietic stem cell proliferation" ;
rdfs:comment "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0072089 .
obo:CHEBI_9212 a rdfs:Class ;
rdfs:label "sparfloxacin" ;
rdfs:subClassOf obo:CHEBI_23765 , obo:CHEBI_26512 , obo:CHEBI_46848 , obo:CHEBI_86324 , obo:CHEBI_87211 .
obo:GO_0040011 a rdfs:Class ;
rdfs:label "locomotion" ;
rdfs:comment "Self-propelled movement of a cell or organism from one location to another." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CL_0002032 a rdfs:Class ;
rdfs:label "hematopoietic oligopotent progenitor cell" ;
rdfs:comment "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000988 , obo:CL_0008001 .
obo:GO_0060045 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0055023 , obo:GO_0060043 , obo:GO_0065007 .
obo:CHEBI_81758 a rdfs:Class ;
rdfs:label "cyproconazole" ;
rdfs:comment "A diastereoisomeric mixture composed of the enantiomeric pair (2R,3S)- and (2S,3R)-cyproconazole in ratio 1:1 with the enantiomeric pair (2R,3R)- and (2S,3S)-cyproconazole. A broad spectrum fungicide, it is used on cereals and other field crops used to control Septoria, rust, powdery mildew and other diseases." ;
rdfs:subClassOf obo:CHEBI_60915 , obo:CHEBI_87067 , obo:CHEBI_87100 .
obo:CHEBI_59358 a rdfs:Class ;
rdfs:label "cefotetan(2-)" ;
rdfs:comment "The dianion formed by removal of a proton from each of the carboxylic acid groups of cefotetan." ;
rdfs:subClassOf obo:CHEBI_28965 .
obo:CL_0002072 a rdfs:Class ;
rdfs:label "nodal myocyte" ;
rdfs:comment "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery." ;
rdfs:subClassOf obo:CL_0002086 .
obo:CHEBI_26151 a rdfs:Class ;
rdfs:label "piperidines" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:CHEBI_63699 a rdfs:Class ;
rdfs:label "moxifloxacinium(1+)" ;
rdfs:comment "An organic cation obtained by protonation of moxifloxacin." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:PHIPO_0000776 a rdfs:Class ;
rdfs:label "sensitive to trichostatin A"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to trichostatin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0014852 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system." ;
rdfs:subClassOf obo:GO_0014819 .
obo:UBERON_0001081 a rdfs:Class ;
rdfs:label "endocardium of ventricle" ;
rdfs:comment "Endocardium that is part of the cardiac ventricle." ;
rdfs:subClassOf obo:UBERON_0002165 .
obo:UBERON_0001628 a rdfs:Class ;
rdfs:label "posterior communicating artery" ;
rdfs:comment "One of a pair of right-sided and left-sided blood vessels in the circle of Willis. It connects the three cerebral arteries of the same side. Anteriorly, it is one portion of the terminal trifurcation of the internal carotid artery. The anterior cerebral artery and the middle cerebral artery are the other two branches of the trifurcation. Posteriorly, it communicates with the posterior cerebral artery." ;
rdfs:subClassOf obo:UBERON_0004573 , obo:UBERON_0006347 , obo:UBERON_0015212 .
obo:UBERON_0002956 a rdfs:Class ;
rdfs:label "granular layer of cerebellar cortex" ;
rdfs:comment "The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." ;
rdfs:subClassOf obo:UBERON_0004130 .
obo:BSPO_0001101 a rdf:Property ;
rdfs:range .
obo:NCBITaxon_554915 a rdfs:Class ;
rdfs:label "Amoebozoa" ;
rdfs:subClassOf obo:NCBITaxon_2759 .
obo:UBERON_0007376 a rdfs:Class ;
rdfs:label "outer epithelium" ;
rdfs:comment "The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003102 .
obo:GO_0046548 a rdfs:Class ;
rdfs:label "retinal rod cell development" ;
rdfs:comment "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0042462 .
obo:CHEBI_78694 a rdfs:Class ;
rdfs:label "(S)-bifonazole" ;
rdfs:comment "A 1-[biphenyl-4-yl(phenyl)methyl]imidazole that is the S-enantiomer of bifonazole." ;
rdfs:subClassOf obo:CHEBI_78692 .
obo:GO_0008283 a rdfs:Class ;
rdfs:label "cell population proliferation" ;
rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a cell population." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0043534 a rdfs:Class ;
rdfs:label "blood vessel endothelial cell migration" ;
rdfs:comment "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0043542 .
obo:GO_0045934 a rdfs:Class ;
rdfs:label "negative regulation of nucleobase-containing compound metabolic process" ;
rdfs:comment "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0019219 , obo:GO_0065007 .
obo:GO_0035767 a rdfs:Class ;
rdfs:label "endothelial cell chemotaxis" ;
rdfs:comment "The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0043542 , obo:GO_0060326 .
obo:GO_0060433 a rdfs:Class ;
rdfs:label "bronchus development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs." ;
rdfs:subClassOf obo:GO_0030323 , obo:GO_0048856 .
obo:GO_0010656 a rdfs:Class ;
rdfs:label "negative regulation of muscle cell apoptotic process" ;
rdfs:comment "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." ;
rdfs:subClassOf obo:GO_0010660 , obo:GO_0043066 , obo:GO_0065007 .
obo:UBERON_0003643 a rdfs:Class ;
rdfs:label "respiratory system arterial blood vessel" ;
rdfs:comment "An arterial blood vessel that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003504 , obo:UBERON_0003509 .
obo:PHIPO_0001057 a rdfs:Class ;
rdfs:label "normal unicellular colony shape"@en ;
rdfs:comment "A single species phenotype where the shape of a colony of unicellular individuals is normal (indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001049 .
obo:PR_000001281 a rdfs:Class ;
rdfs:label "ADP-ribosyl cyclase" ;
rdfs:comment "A protein that contains the ADP-ribosyl cyclase domain (Pfam:PF02267)." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0099576 a rdfs:Class ;
rdfs:label "regulation of protein catabolic process at postsynapse, modulating synaptic transmission" ;
rdfs:comment "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse." ;
rdfs:subClassOf obo:GO_0042176 , obo:GO_0099170 .
obo:GO_0007610 a rdfs:Class ;
rdfs:label "behavior" ;
rdfs:comment "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." ;
rdfs:subClassOf obo:GO_0032501 .
obo:UBERON_0003439 a rdfs:Class ;
rdfs:label "nerve of trunk region" ;
rdfs:comment "A nerve that is part of the trunk region of the body (not to be confused with a nerve trunk)." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:CHEBI_131927 a rdfs:Class ;
rdfs:label "dicarboxylic acids and O-substituted derivatives" ;
rdfs:comment "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." ;
rdfs:subClassOf obo:CHEBI_36586 .
obo:GO_0010631 a rdfs:Class ;
rdfs:label "epithelial cell migration" ;
rdfs:comment "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism." ;
rdfs:subClassOf obo:GO_0001667 , obo:GO_0016477 .
obo:CHEBI_38068 a rdfs:Class ;
rdfs:label "antimalarial" ;
rdfs:comment "A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human." ;
rdfs:subClassOf obo:CHEBI_64915 .
obo:PR_Q63994 a rdfs:Class ;
rdfs:label "myeloid cell surface antigen CD33 (mouse)" ;
rdfs:comment "A CD33 molecule that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001892 , obo:PR_000029032 .
obo:UBERON_0016509 a rdfs:Class ;
rdfs:label "cavity of right ventricle" ;
rdfs:comment "Luminal space of the right ventricle of the heart." ;
rdfs:subClassOf obo:UBERON_0002553 , obo:UBERON_0035763 .
obo:CHEBI_37627 a rdfs:Class ;
rdfs:label "L-glucopyranose" ;
rdfs:comment "The L-enantiomer of glucopyranose." ;
rdfs:subClassOf obo:CHEBI_37624 , obo:CHEBI_37661 .
obo:CL_0002585 a rdfs:Class ;
rdfs:label "retinal blood vessel endothelial cell" ;
rdfs:comment "A blood vessel endothelial cell that is part of the retina." ;
rdfs:subClassOf obo:CL_0000071 , obo:CL_0009004 .
obo:CHEBI_41032 a rdfs:Class ;
rdfs:label "5-methyl[1,2,4]triazolo[3,4-b][1,3]benzothiazol-1-ium" ;
rdfs:subClassOf obo:CHEBI_25697 .
obo:PATO_0001580 a rdfs:Class ;
rdfs:label "increased contractility" ;
rdfs:comment "A contractility which is relatively high." ;
rdfs:subClassOf obo:PATO_0001690 , obo:PATO_0002305 .
obo:GO_1905484 a rdfs:Class ;
rdfs:label "negative regulation of motor neuron migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905483 , obo:GO_2001223 .
obo:CHEBI_9587 a rdfs:Class ;
rdfs:label "ticarcillin" ;
rdfs:comment "A penicillin compound having a 6β-[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino side-group." ;
rdfs:subClassOf obo:CHEBI_88187 .
obo:GO_0021635 a rdfs:Class ;
rdfs:label "trigeminal nerve maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." ;
rdfs:subClassOf obo:GO_0021605 , obo:GO_0021700 .
obo:CHEBI_138015 a rdfs:Class ;
rdfs:label "endocrine disruptor" ;
rdfs:comment "Any compound that can disrupt the functions of the endocrine (hormone) system" ;
rdfs:subClassOf obo:CHEBI_51061 .
obo:GO_0021681 a rdfs:Class ;
rdfs:label "cerebellar granular layer development" ;
rdfs:comment "The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0013161 a rdfs:Class ;
rdfs:label "left lateral ventricle" ;
rdfs:comment "A telencephalic ventricle that is in_the_left_side_of a telencephalon." ;
rdfs:subClassOf obo:UBERON_0002285 , obo:UBERON_0015212 .
obo:GO_0016740 a rdfs:Class ;
rdfs:label "transferase activity" ;
rdfs:comment "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." ;
rdfs:subClassOf obo:GO_0003824 .
obo:PHIPO_0000359 a rdfs:Class ;
rdfs:label "decreased pathogen penetration into host"@en ;
rdfs:comment "A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism is decreased." ;
rdfs:subClassOf obo:PHIPO_0000331 .
obo:GO_0099112 a rdfs:Class ;
rdfs:label "microtubule polymerization based protein transport" ;
rdfs:comment "The transport of a protein driven by polymerization of a microtubule to which it is attached." ;
rdfs:subClassOf obo:GO_0006886 , obo:GO_0046907 , obo:GO_0099118 .
obo:CL_0001035 a rdfs:Class ;
rdfs:label "bone cell" ;
rdfs:comment "A connective tissue cell found in bone." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:PHIPO_0000089 a rdfs:Class ;
rdfs:label "obsolete normal fragmentation" .
obo:PHIPO_0000245 a rdfs:Class ;
rdfs:label "abolished protein localization"@en ;
rdfs:comment "A single organism phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found." ;
rdfs:subClassOf obo:PHIPO_0000239 .
obo:CHEBI_24061 a rdfs:Class ;
rdfs:label "fluorine atom" ;
rdfs:subClassOf obo:CHEBI_24473 .
obo:CHEBI_76395 a rdfs:Class ;
rdfs:label "EC 2.3.1.48 (histone acetyltransferase) inhibitor" ;
rdfs:comment "An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48)." ;
rdfs:subClassOf obo:CHEBI_76878 .
obo:CHEBI_18291 a rdfs:Class ;
rdfs:label "manganese atom" ;
rdfs:subClassOf obo:CHEBI_33352 .
obo:GO_0005000 a rdfs:Class ;
rdfs:label "vasopressin receptor activity" ;
rdfs:comment "Combining with vasopressin to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0008528 , obo:GO_0038023 .
obo:CHEBI_133011 a rdfs:Class ;
rdfs:label "oxytetracycline zwitterion" ;
rdfs:comment "A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the adjacent tertiary amino group of oxytetracycline; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_144644 , obo:CHEBI_27369 .
obo:CL_1000482 a rdfs:Class ;
rdfs:label "myocardial endocrine cell of interventricular septum" ;
rdfs:comment "A myocardial endocrine cell that is part of the interventricular septum." ;
rdfs:subClassOf obo:CL_0002074 , obo:CL_2000022 .
obo:UBERON_0002198 a rdfs:Class ;
rdfs:label "neurohypophysis" ;
rdfs:comment "The posterior part of the pituitary gland that secretes hormones involved in blood pressure regulation such as oxytocin and antidiuretic hormon." ;
rdfs:subClassOf obo:UBERON_0003296 , obo:UBERON_0003937 , obo:UBERON_0004121 , obo:UBERON_0010134 .
obo:PHIPO_0000166 a rdfs:Class ;
rdfs:label "obsolete chlorosis phenotype" .
obo:GO_0097094 a rdfs:Class ;
rdfs:label "craniofacial suture morphogenesis" ;
rdfs:comment "The process in which any suture between cranial and/or facial bones is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CL_4310112 a rdfs:Class ;
rdfs:label "SN GATA3-PAX8 GABA GABAergic interneuron (Primate)" ;
rdfs:comment "A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN GATA3-PAX8 GABA." ;
rdfs:subClassOf obo:CL_0011005 .
obo:CHEBI_33306 a rdfs:Class ;
rdfs:label "carbon group element atom" ;
rdfs:subClassOf obo:CHEBI_33560 .
obo:CL_0002596 a rdfs:Class ;
rdfs:label "smooth muscle cell of the carotid artery" ;
rdfs:comment "Smooth muscle cell of the carotid artery." ;
rdfs:subClassOf obo:CL_0000359 , obo:CL_0019018 .
obo:GO_0007155 a rdfs:Class ;
rdfs:label "cell adhesion" ;
rdfs:comment "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." ;
rdfs:subClassOf obo:GO_0009987 .
obo:PHIPO_0000202 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host protein complex binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which the binding of one protein to a protein complex is abnormal. The protein whose binding to the protein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene." .
obo:UBERON_0004815 a rdfs:Class ;
rdfs:label "lower respiratory tract epithelium" ;
rdfs:comment "An epithelium that is part of a lower respiratory tract [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004802 .
obo:GO_0061524 a rdfs:Class ;
rdfs:label "central canal development" ;
rdfs:comment "The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_472657 a rdfs:Class ;
rdfs:label "cefixime" ;
rdfs:comment "A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections." ;
rdfs:subClassOf obo:CHEBI_23066 .
obo:GO_0043615 a rdfs:Class ;
rdfs:label "astrocyte cell migration" ;
rdfs:comment "The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord." ;
rdfs:subClassOf obo:GO_0008347 , obo:GO_0016477 .
obo:UBERON_0003687 a rdfs:Class ;
rdfs:label "foramen magnum" ;
rdfs:comment "In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0013685 .
obo:UBERON_0006930 a rdfs:Class ;
rdfs:label "glandular cuboidal epithelium" ;
rdfs:subClassOf obo:UBERON_0000484 , obo:UBERON_0006799 .
obo:UBERON_0014903 a rdfs:Class ;
rdfs:label "primordial vasculature" ;
rdfs:comment "A portion of tissue that will develop into vasculature." ;
rdfs:subClassOf obo:UBERON_0001048 .
obo:PR_P60041 a rdfs:Class ;
rdfs:label "somatostatin (mouse)" ;
rdfs:comment "A somatostatin that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000015665 , obo:PR_000029032 .
obo:CL_0000082 a rdfs:Class ;
rdfs:label "epithelial cell of lung" ;
rdfs:comment "An epithelial cell of the lung." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002632 .
obo:UBERON_0002365 a rdfs:Class ;
rdfs:label "exocrine gland" ;
rdfs:comment "A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:CL_0008060 a rdfs:Class ;
rdfs:label "GABA-Glut neuron" ;
rdfs:comment "A neuron that releases both gamma-aminobutyric acid and glutamate as vesicular neurotransmitters." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_0000617 , obo:CL_0000679 .
obo:CHEBI_40009 a rdfs:Class ;
rdfs:label "D-cycloserine" ;
rdfs:comment "A 4-amino-1,2-oxazolidin-3-one that has R configuration. It is an antibiotic produced by Streptomyces garyphalus or S. orchidaceus and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of D-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of L-alanine racemase (which forms D-alanine from L-alanine) and D-alanine—D-alanine ligase (which incorporates D-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis)." ;
rdfs:subClassOf obo:CHEBI_23503 , obo:CHEBI_25558 , obo:CHEBI_25807 .
obo:CHEBI_231911 a rdfs:Class ;
rdfs:label "renoprotective agent" ;
rdfs:comment "Any compound that is able to prevent damage to the kidneys." ;
rdfs:subClassOf obo:CHEBI_50267 .
obo:CHEBI_59203 a rdfs:Class ;
rdfs:label "straight-chain fatty acid anion" ;
rdfs:comment "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:GO_0021699 a rdfs:Class ;
rdfs:label "cerebellar cortex maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:GO_0061564 a rdfs:Class ;
rdfs:label "axon development" ;
rdfs:comment "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)." ;
rdfs:subClassOf obo:GO_0031175 .
obo:UBERON_0002357 a rdfs:Class ;
rdfs:label "serous pericardium" ;
rdfs:comment "Serous membrane which is divided into parietal and visceral serous pericardium." ;
rdfs:subClassOf obo:UBERON_0000042 .
obo:GO_0004993 a rdfs:Class ;
rdfs:label "G protein-coupled serotonin receptor activity" ;
rdfs:comment "Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates." ;
rdfs:subClassOf obo:GO_0008227 .
obo:GO_0045921 a rdfs:Class ;
rdfs:label "positive regulation of exocytosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of exocytosis." ;
rdfs:subClassOf obo:GO_0017157 , obo:GO_0065007 , obo:GO_1903532 .
obo:CHEBI_90799 a rdfs:Class ;
rdfs:label "dipeptide zwitterion" ;
rdfs:comment "Any peptide zwitterion comprising two amino acid residues. Major structure at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_60466 .
obo:UBERON_0035642 a rdfs:Class ;
rdfs:label "laryngeal nerve" ;
rdfs:comment "Any nerve that innervates the larynx." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:PHIPO_0001026 a rdfs:Class ;
rdfs:label "increased protein level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of protein measured in a cell is higher than normal. Total protein or a specific protein may be affected." ;
rdfs:subClassOf obo:PHIPO_0001025 , obo:PHIPO_0001036 .
obo:CL_4033008 a rdfs:Class ;
rdfs:label "vein endothelial cell of respiratory system" ;
rdfs:comment "A(n) vein endothelial cell that is part of a(n) respiratory system." ;
rdfs:subClassOf obo:CL_0002543 .
obo:GO_0001834 a rdfs:Class ;
rdfs:label "trophectodermal cell proliferation" ;
rdfs:comment "The proliferation of cells in the trophectoderm." ;
rdfs:subClassOf obo:GO_0008283 .
obo:GO_0030252 a rdfs:Class ;
rdfs:label "growth hormone secretion" ;
rdfs:comment "The regulated release of growth hormone from secretory granules into the blood." ;
rdfs:subClassOf obo:GO_0030072 .
obo:GO_0060363 a rdfs:Class ;
rdfs:label "cranial suture morphogenesis" ;
rdfs:comment "The process in which any suture between cranial bones is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0097094 .
obo:GO_0021652 a rdfs:Class ;
rdfs:label "rhombomere 1 formation" ;
rdfs:comment "The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." ;
rdfs:subClassOf obo:GO_0021594 , obo:GO_0048646 .
obo:GO_0043066 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0043069 , obo:GO_0065007 .
obo:UBERON_0000011 a rdfs:Class ;
rdfs:label "parasympathetic nervous system" ;
rdfs:comment "The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia[GO]." ;
rdfs:subClassOf obo:UBERON_0010314 , obo:UBERON_0011216 .
obo:UBERON_0004267 a rdfs:Class ;
rdfs:label "back connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a back [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:CL_4301597 a rdfs:Class ;
rdfs:label "Astro-OLF NN_2 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Hs3st3a1 (Mmus), Slco1c1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1167 Astro-OLF NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300360 .
obo:GO_0021522 a rdfs:Class ;
rdfs:label "spinal cord motor neuron differentiation" ;
rdfs:comment "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0021515 , obo:GO_0021953 , obo:GO_0030154 .
obo:GO_0031113 a rdfs:Class ;
rdfs:label "regulation of microtubule polymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of microtubule polymerization." ;
rdfs:subClassOf obo:GO_0031110 , obo:GO_0032271 , obo:GO_0065007 , obo:GO_1902903 .
obo:CHEBI_25754 a rdfs:Class ;
rdfs:label "oxo carboxylic acid" ;
rdfs:comment "Any compound that has an aldehydic or ketonic group as well as a carboxylic acid group in the same molecule." ;
rdfs:subClassOf obo:CHEBI_33575 .
obo:CL_0010009 a rdfs:Class ;
rdfs:label "camera-type eye photoreceptor cell" ;
rdfs:comment "Any photoreceptor cell that is part of some camera-type eye." ;
rdfs:subClassOf obo:CL_0000210 , obo:CL_0000287 , obo:CL_0009004 .
obo:GO_1900195 a rdfs:Class ;
rdfs:label "positive regulation of oocyte maturation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of oocyte maturation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900193 , obo:GO_1903431 , obo:GO_2000243 .
obo:GO_0014743 a rdfs:Class ;
rdfs:label "regulation of muscle hypertrophy" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of muscle hypertrophy." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090257 .
obo:GO_2000137 a rdfs:Class ;
rdfs:label "negative regulation of cell proliferation involved in heart morphogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0065007 , obo:GO_2000136 .
obo:CL_0002043 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-negative multipotent progenitor cell" ;
rdfs:comment "A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative." ;
rdfs:subClassOf obo:CL_0000837 .
obo:GO_0000049 a rdfs:Class ;
rdfs:label "tRNA binding" ;
rdfs:comment "Binding to a transfer RNA." ;
rdfs:subClassOf obo:GO_0003723 , obo:GO_0005488 .
obo:CHEBI_17630 a rdfs:Class ;
rdfs:label "kanamycin A" ;
rdfs:subClassOf obo:CHEBI_24951 .
obo:GO_0043473 a rdfs:Class ;
rdfs:label "pigmentation" ;
rdfs:comment "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_0005880 a rdfs:Class ;
rdfs:label "nuclear microtubule" ;
rdfs:comment "Any microtubule in the nucleus of a cell." ;
rdfs:subClassOf obo:GO_0005874 .
obo:GO_0015629 a rdfs:Class ;
rdfs:label "actin cytoskeleton" ;
rdfs:comment "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." ;
rdfs:subClassOf obo:GO_0005856 .
obo:CHEBI_60466 a rdfs:Class ;
rdfs:label "peptide zwitterion" ;
rdfs:comment "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:GO_0045839 a rdfs:Class ;
rdfs:label "negative regulation of mitotic nuclear division" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." ;
rdfs:subClassOf obo:GO_0007088 , obo:GO_0010948 , obo:GO_0045930 , obo:GO_0051784 , obo:GO_0065007 .
obo:UBERON_0001714 a rdfs:Class ;
rdfs:label "cranial ganglion" ;
rdfs:comment "The groups of nerve cell bodies associated with the twelve cranial nerves." ;
rdfs:subClassOf obo:UBERON_0000045 .
obo:CHEBI_25388 a rdfs:Class ;
rdfs:label "monohydroxybenzoate" ;
rdfs:comment "A hydroxybenzoate carrying a single hydroxy substituent at unspecified position." ;
rdfs:subClassOf obo:CHEBI_24675 .
obo:CHEBI_25481 a rdfs:Class ;
rdfs:label "naphthoquinone" ;
rdfs:comment "A polycyclic aromatic ketone metabolite of naphthalene." ;
rdfs:subClassOf obo:CHEBI_36141 .
obo:CHEBI_35757 a rdfs:Class ;
rdfs:label "monocarboxylic acid anion" ;
rdfs:comment "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:UBERON_0009129 a rdfs:Class ;
rdfs:label "right atrium endocardium" ;
rdfs:comment "Endocardium that is part of the right atrium." ;
rdfs:subClassOf obo:UBERON_0002165 , obo:UBERON_0002166 .
obo:GO_0060255 a rdfs:Class ;
rdfs:label "regulation of macromolecule metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_0007267 a rdfs:Class ;
rdfs:label "cell-cell signaling" ;
rdfs:comment "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." ;
rdfs:subClassOf obo:GO_0007154 , obo:GO_0023052 .
obo:CHEBI_35618 a rdfs:Class ;
rdfs:label "aromatic ether" ;
rdfs:comment "Any ether in which the oxygen is attached to at least one aryl substituent." ;
rdfs:subClassOf obo:CHEBI_25698 , obo:CHEBI_33659 .
obo:UBERON_0004535 a rdfs:Class ;
rdfs:label "cardiovascular system" ;
rdfs:comment "Anatomical system that has as its parts the heart and blood vessels." ;
rdfs:subClassOf obo:UBERON_0000467 , obo:UBERON_0010314 .
obo:GO_2000381 a rdfs:Class ;
rdfs:label "negative regulation of mesoderm development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0065007 , obo:GO_2000380 .
obo:PHIPO_0000688 a rdfs:Class ;
rdfs:label "resistance to amphotericin B"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to amphotericin B. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1900376 a rdfs:Class ;
rdfs:label "regulation of secondary metabolite biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0043455 , obo:GO_0065007 .
obo:GO_0048545 a rdfs:Class ;
rdfs:label "response to steroid hormone" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." ;
rdfs:subClassOf obo:GO_0009725 , obo:GO_0033993 , obo:GO_0050896 .
obo:GO_0001569 a rdfs:Class ;
rdfs:label "branching involved in blood vessel morphogenesis" ;
rdfs:comment "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system." ;
rdfs:subClassOf obo:GO_0048754 .
obo:UBERON_0003364 a rdfs:Class ;
rdfs:label "epithelium of right lung" ;
rdfs:comment "An epithelium that is part of a right lung [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000115 , obo:UBERON_0000483 .
obo:GO_0100001 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle contraction by action potential" ;
rdfs:comment "Any action potential process that regulates skeletal muscle contraction." ;
rdfs:subClassOf obo:GO_0001508 , obo:GO_0014819 .
obo:GO_0010604 a rdfs:Class ;
rdfs:label "positive regulation of macromolecule metabolic process" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0060255 , obo:GO_0065007 .
obo:PR_000013433 a rdfs:Class ;
rdfs:label "parathyroid hormone-related protein" ;
rdfs:comment "A protein that is a translation product of the human PTHLH gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_64946 a rdfs:Class ;
rdfs:label "anti-HIV agent" ;
rdfs:comment "An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus." ;
rdfs:subClassOf obo:CHEBI_22587 .
obo:UBERON_0007237 a rdfs:Class ;
rdfs:label "1st arch mandibular component" ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:UBERON_0004701 a rdfs:Class ;
rdfs:label "venous system endothelium" ;
rdfs:comment "An endothelium that is part of a venous system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0004852 .
obo:GO_2000736 a rdfs:Class ;
rdfs:label "regulation of stem cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of stem cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:GO_0035912 a rdfs:Class ;
rdfs:label "dorsal aorta morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0035909 .
obo:GO_0014046 a rdfs:Class ;
rdfs:label "dopamine secretion" ;
rdfs:comment "The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone." ;
rdfs:subClassOf obo:GO_0023061 , obo:GO_0046903 , obo:GO_0050432 .
obo:GO_0099518 a rdfs:Class ;
rdfs:label "vesicle cytoskeletal trafficking" ;
rdfs:comment "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0030705 , obo:GO_0046907 , obo:GO_0051650 .
obo:PHIPO_0001333 a rdfs:Class ;
rdfs:label "resistance to thiram"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to thiram. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0013159 a rdfs:Class ;
rdfs:label "epithalamus mantle layer" ;
rdfs:subClassOf obo:UBERON_0004061 .
obo:PATO_0002300 a rdfs:Class ;
rdfs:label "increased quality" ;
rdfs:comment "A quality that has a value that is increased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0000001 , obo:PATO_0000069 .
obo:CHEBI_38161 a rdfs:Class ;
rdfs:label "chelator" ;
rdfs:comment "A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate." ;
rdfs:subClassOf obo:CHEBI_52214 .
obo:GO_0043604 a rdfs:Class ;
rdfs:label "amide biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0043603 .
obo:GO_0030594 a rdfs:Class ;
rdfs:label "neurotransmitter receptor activity" ;
rdfs:comment "Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0038023 .
obo:GO_1903347 a rdfs:Class ;
rdfs:label "negative regulation of bicellular tight junction assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901889 , obo:GO_2000810 .
obo:PHIPO_0000418 a rdfs:Class ;
rdfs:label "normal carbohydrate binding"@en ;
rdfs:comment "A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000430 .
obo:GO_0106027 a rdfs:Class ;
rdfs:label "neuron projection organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0120036 .
obo:PHIPO_0001382 a rdfs:Class ;
rdfs:label "resistance to fenpiclonil" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fenpiclonil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000018 a rdfs:Class ;
rdfs:label "lipid droplets present in decreased numbers" ;
rdfs:comment "A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer lipid droplets than normal." ;
rdfs:subClassOf obo:PHIPO_0000474 .
obo:GO_0060571 a rdfs:Class ;
rdfs:label "morphogenesis of an epithelial fold" ;
rdfs:comment "The morphogenetic process in which an epithelial sheet bends along a linear axis." ;
rdfs:subClassOf obo:GO_0002009 , obo:GO_0009653 .
obo:CHEBI_41275 a rdfs:Class ;
rdfs:label "1H-benzimidazole" ;
rdfs:comment "The 1H-tautomer of benzimidazole." ;
rdfs:subClassOf obo:CHEBI_36622 , obo:CHEBI_38180 .
obo:GO_2001051 a rdfs:Class ;
rdfs:label "positive regulation of tendon cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of tendon cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0065007 , obo:GO_2001049 .
obo:GO_2000404 a rdfs:Class ;
rdfs:label "regulation of T cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of T cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000401 .
obo:UBERON_0000353 a rdfs:Class ;
rdfs:label "parenchyma" ;
rdfs:comment "Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:PATO_0000957 a rdfs:Class ;
rdfs:label "opacity" ;
rdfs:comment "An optical quality which obtains by virtue of the ability of the bearer to absorb visible light." ;
rdfs:subClassOf obo:PATO_0001300 .
obo:UBERON_0001898 a rdfs:Class ;
rdfs:label "hypothalamus" ;
rdfs:comment "A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:PHIPO_0000270 a rdfs:Class ;
rdfs:label "normal pathogen protein and host protein colocalization within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the colocalization of a pathogen protein and a host protein within a host cell is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000236 .
obo:UBERON_0022350 a rdfs:Class ;
rdfs:label "visceral serous membrane" ;
rdfs:comment "Serous membrane layer that is adjacent to and lines an organ." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:GO_0002695 a rdfs:Class ;
rdfs:label "negative regulation of leukocyte activation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation." ;
rdfs:subClassOf obo:GO_0002683 , obo:GO_0002694 , obo:GO_0050866 , obo:GO_0065007 .
obo:GO_0002534 a rdfs:Class ;
rdfs:label "cytokine production involved in inflammatory response" ;
rdfs:comment "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0001816 , obo:GO_0002532 .
obo:PHIPO_0001263 a rdfs:Class ;
rdfs:label "host defense-induced RNA level phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, which affects the level of a host produced RNA during infection." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:PHIPO_0000578 a rdfs:Class ;
rdfs:label "resistance to nifurtimox"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to nifurtimox. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001412 a rdfs:Class ;
rdfs:label "sensitive to dalfopristin" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to dalfopristin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0016321 a rdfs:Class ;
rdfs:label "female meiosis chromosome segregation" ;
rdfs:comment "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." ;
rdfs:subClassOf obo:GO_0045132 , obo:GO_0098813 .
obo:GO_1900016 a rdfs:Class ;
rdfs:label "negative regulation of cytokine production involved in inflammatory response" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response." ;
rdfs:subClassOf obo:GO_0001818 , obo:GO_0065007 , obo:GO_1900015 .
obo:GO_1902710 a rdfs:Class ;
rdfs:label "GABA receptor complex" ;
rdfs:comment "A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0043235 .
obo:GO_0034765 a rdfs:Class ;
rdfs:label "regulation of monoatomic ion transmembrane transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0034762 , obo:GO_0043269 , obo:GO_0065007 .
obo:PHIPO_0000500 a rdfs:Class ;
rdfs:label "obsolete abnormal biosynthesis of deoxynivalenol" ;
rdfs:comment "A single organism phenotype in which the biosynthesis of deoxynivalenol is abnormal (i.e. different than the wild type)." .
obo:UBERON_0005567 a rdfs:Class ;
rdfs:label "rhombomere 1 lateral wall" ;
rdfs:comment "A rhombomere lateral wall that is part of a rhombomere 1." ;
rdfs:subClassOf obo:UBERON_0005501 .
obo:UBERON_0005426 a rdfs:Class ;
rdfs:label "lens vesicle" ;
rdfs:comment "Portion of tissue that gives rise to the lens." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:GO_0070587 a rdfs:Class ;
rdfs:label "regulation of cell-cell adhesion involved in gastrulation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation." ;
rdfs:subClassOf obo:GO_0022407 , obo:GO_0065007 .
obo:CL_1000310 a rdfs:Class ;
rdfs:label "adipocyte of epicardial fat of right ventricle" ;
rdfs:comment "An adipocyte that is part of the epicardial fat of right ventricle." ;
rdfs:subClassOf obo:CL_1000309 .
obo:GO_0035264 a rdfs:Class ;
rdfs:label "multicellular organism growth" ;
rdfs:comment "The increase in size or mass of an entire multicellular organism, as opposed to cell growth." ;
rdfs:subClassOf obo:GO_0032501 , obo:GO_0048589 .
obo:GO_1903977 a rdfs:Class ;
rdfs:label "positive regulation of glial cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of glial cell migration." ;
rdfs:subClassOf obo:GO_0030335 , obo:GO_0065007 , obo:GO_1903975 .
obo:GO_0140546 a rdfs:Class ;
rdfs:label "defense response to symbiont" ;
rdfs:comment "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host." ;
rdfs:subClassOf obo:GO_0098542 .
obo:GO_0030263 a rdfs:Class ;
rdfs:label "apoptotic chromosome condensation" ;
rdfs:comment "The compaction of chromatin during apoptosis." ;
rdfs:subClassOf obo:GO_0030261 .
obo:UBERON_0000982 a rdfs:Class ;
rdfs:label "skeletal joint" ;
rdfs:comment "Anatomical structure that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]." ;
rdfs:subClassOf obo:UBERON_0004905 .
obo:GO_0061553 a rdfs:Class ;
rdfs:label "ganglion maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0071695 .
obo:CL_4023016 a rdfs:Class ;
rdfs:label "VIP GABAergic interneuron" ;
rdfs:comment "A transcriptomically distinct GABAergic neuron derived from the CGE and that expresses the vasoactive intestinal polypeptide. Its soma is located in the forebrain." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_4023064 .
obo:CHEBI_36785 a rdfs:Class ;
rdfs:label "carbobicyclic compound" ;
rdfs:comment "A bicyclic compound in which all the ring atoms are carbon." ;
rdfs:subClassOf obo:CHEBI_33636 , obo:CHEBI_35294 .
obo:GO_0000902 a rdfs:Class ;
rdfs:label "cell morphogenesis" ;
rdfs:comment "The developmental process in which the size or shape of a cell is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PATO_0002000 a rdfs:Class ;
rdfs:label "lacks all parts of type" ;
rdfs:comment "A quality of physical entities inhering in a bearer by virtue of the bearer's lacking a physical part as specified by the additional entity." ;
rdfs:subClassOf obo:PATO_0001999 .
a rdfs:Class ;
rdfs:label "central canal, spinal cord/medulla" ;
rdfs:subClassOf , obo:UBERON_0002291 .
obo:GO_0007530 a rdfs:Class ;
rdfs:label "sex determination" ;
rdfs:comment "Any process that establishes and transmits the specification of sexual status of an individual organism." ;
rdfs:subClassOf obo:GO_0003006 .
obo:GO_0003164 a rdfs:Class ;
rdfs:label "His-Purkinje system development" ;
rdfs:comment "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." ;
rdfs:subClassOf obo:GO_0003229 , obo:GO_0048856 .
obo:PHIPO_0000498 a rdfs:Class ;
rdfs:label "abnormal toxin biosynthetic process"@en ;
rdfs:comment "A single organism phenotype in which the toxin biosynthetic process is abnormal (i.e. different than the wild type)." ;
rdfs:subClassOf obo:PHIPO_0000496 , obo:PHIPO_0000929 .
obo:UBERON_0014540 a rdfs:Class ;
rdfs:label "white matter lamina of cerebellum" ;
rdfs:comment "The white laminae of cerebellum is subdivision of the cerebellar cortex comprised of myelinated axons lying deep to the granule cell layer of the cerebellar cortex." ;
rdfs:subClassOf obo:UBERON_0014530 .
obo:GO_0010634 a rdfs:Class ;
rdfs:label "positive regulation of epithelial cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of epithelial cell migration." ;
rdfs:subClassOf obo:GO_0010632 , obo:GO_0030335 , obo:GO_0065007 .
obo:GO_0061629 a rdfs:Class ;
rdfs:label "RNA polymerase II-specific DNA-binding transcription factor binding" ;
rdfs:comment "Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription." ;
rdfs:subClassOf obo:GO_0140297 .
obo:GO_0050881 a rdfs:Class ;
rdfs:label "musculoskeletal movement" ;
rdfs:comment "The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system." ;
rdfs:subClassOf obo:GO_0050879 , obo:GO_0050905 .
obo:GO_0043207 a rdfs:Class ;
rdfs:label "response to external biotic stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." ;
rdfs:subClassOf obo:GO_0009605 , obo:GO_0009607 .
obo:PR_000001843 a rdfs:Class ;
rdfs:label "Thy-1 membrane glycoprotein" ;
rdfs:comment "A protein that is a translation product of the human THY1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0060142 a rdfs:Class ;
rdfs:label "regulation of syncytium formation by plasma membrane fusion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0070507 a rdfs:Class ;
rdfs:label "regulation of microtubule cytoskeleton organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." ;
rdfs:subClassOf obo:GO_0032886 , obo:GO_0051493 , obo:GO_0065007 .
obo:CHEBI_132717 a rdfs:Class ;
rdfs:label "bleaching agent" ;
rdfs:comment "A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties." ;
rdfs:subClassOf obo:CHEBI_33893 .
obo:UBERON_0018257 a rdfs:Class ;
rdfs:label "submucosa of digestive tract" ;
rdfs:comment "Any portion of submucosa that lines the digestive tract." ;
rdfs:subClassOf obo:UBERON_0000009 .
obo:GO_0170034 a rdfs:Class ;
rdfs:label "L-amino acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of L-amino acids, the L-enantiomers of amino acids." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0170033 , obo:GO_1901607 .
obo:PHIPO_0000817 a rdfs:Class ;
rdfs:label "sensitive to isoniazid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to isoniazid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PR_P35918 a rdfs:Class ;
rdfs:label "vascular endothelial growth factor receptor 2 (mouse)" ;
rdfs:comment "A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000002112 , obo:PR_000029032 .
obo:CHEBI_65212 a rdfs:Class ;
rdfs:label "polysaccharide derivative" ;
rdfs:comment "A carbohydrate derivative that is any derivative of a polysaccharide." ;
rdfs:subClassOf obo:CHEBI_167559 , obo:CHEBI_33694 , obo:CHEBI_63299 .
obo:GO_0050886 a rdfs:Class ;
rdfs:label "endocrine process" ;
rdfs:comment "The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." ;
rdfs:subClassOf obo:GO_0003008 .
obo:CHEBI_83316 a rdfs:Class ;
rdfs:label "EC 1.14.13.72 (methylsterol monooxygenase) inhibitor" ;
rdfs:comment "An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of methylsterol monooxygenase (EC 1.14.13.72)." ;
rdfs:subClassOf obo:CHEBI_76841 .
obo:GO_0048144 a rdfs:Class ;
rdfs:label "fibroblast proliferation" ;
rdfs:comment "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population." ;
rdfs:subClassOf obo:GO_0008283 .
obo:CHEBI_132155 a rdfs:Class ;
rdfs:label "hydroxynaphthoquinone" ;
rdfs:comment "Any naphthoquinone in which the naphthaoquinone moiety is substituted by at least one hydroxy group." ;
rdfs:subClassOf obo:CHEBI_132130 , obo:CHEBI_25481 .
obo:CL_2000042 a rdfs:Class ;
rdfs:label "embryonic fibroblast" ;
rdfs:comment "Any fibroblast that is part of a embryo." ;
rdfs:subClassOf obo:CL_0000057 .
obo:CL_0000458 a rdfs:Class ;
rdfs:label "serotonin secreting cell" ;
rdfs:comment "A cell type that secretes 5-Hydroxytryptamine (serotonin)." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000457 .
obo:CHEBI_50847 a rdfs:Class ;
rdfs:label "immunological adjuvant" ;
rdfs:comment "A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity." ;
rdfs:subClassOf obo:CHEBI_50846 , obo:CHEBI_60809 .
obo:PHIPO_0000344 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host interaction molecular function" .
obo:GO_0048638 a rdfs:Class ;
rdfs:label "regulation of developmental growth" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of developmental growth." ;
rdfs:subClassOf obo:GO_0040008 , obo:GO_0050793 , obo:GO_0065007 .
obo:CL_0002086 a rdfs:Class ;
rdfs:label "specialized cardiac myocyte" ;
rdfs:comment "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart." ;
rdfs:subClassOf obo:CL_0000746 .
obo:GO_1901858 a rdfs:Class ;
rdfs:label "regulation of mitochondrial DNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process." ;
rdfs:subClassOf obo:GO_0051052 , obo:GO_0065007 .
obo:GO_0005635 a rdfs:Class ;
rdfs:label "nuclear envelope" ;
rdfs:comment "The double lipid bilayer that encloses the nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore complexes, which regulate molecular transport." ;
rdfs:subClassOf obo:GO_0031967 .
obo:UBERON_0014451 a rdfs:Class ;
rdfs:label "tongue taste bud" ;
rdfs:comment "A taste bud that is located on the tongue, situated on a gustatory papilla." ;
rdfs:subClassOf obo:UBERON_0001727 , obo:UBERON_0013765 .
obo:CHEBI_61115 a rdfs:Class ;
rdfs:label "EC 3.5.1.98 (histone deacetylase) inhibitor" ;
rdfs:comment "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98)." ;
rdfs:subClassOf obo:CHEBI_76807 .
obo:GO_0080154 a rdfs:Class ;
rdfs:label "regulation of fertilization" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000241 .
obo:GO_0035270 a rdfs:Class ;
rdfs:label "endocrine system development" ;
rdfs:comment "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:UBERON_0011648 a rdfs:Class ;
rdfs:label "jaw muscle" ;
rdfs:subClassOf obo:UBERON_0002376 .
obo:GO_0009547 a rdfs:Class ;
rdfs:label "plastid ribosome" ;
rdfs:comment "A ribosome contained within a plastid." ;
rdfs:subClassOf obo:GO_0000313 , obo:GO_0005840 .
obo:UBERON_0006965 a rdfs:Class ;
rdfs:label "vascular cord" ;
rdfs:comment "The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]." ;
rdfs:subClassOf obo:UBERON_0005423 .
a rdf:Property ;
rdfs:label "site_of" ;
rdfs:comment "c site_of p if c is the bearer of a disposition that is realized by a process that has p as part." ;
rdfs:range .
obo:CHEBI_24859 a rdfs:Class ;
rdfs:label "iodine atom" ;
rdfs:comment "Chemical element with atomic number 53." ;
rdfs:subClassOf obo:CHEBI_24473 .
obo:CHEBI_15986 a rdfs:Class ;
rdfs:label "polynucleotide" ;
rdfs:comment "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." ;
rdfs:subClassOf obo:CHEBI_33695 , obo:CHEBI_61120 .
obo:UBERON_0005944 a rdfs:Class ;
rdfs:label "axial skeleton plus cranial skeleton" ;
rdfs:comment "Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:CHEBI_83820 a rdfs:Class ;
rdfs:label "non-proteinogenic amino acid" ;
rdfs:comment "Any amino-acid that is not naturally encoded in the genetic code of any organism." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:GO_1901212 a rdfs:Class ;
rdfs:label "positive regulation of cardiac chamber formation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac chamber formation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901210 , obo:GO_1901221 .
obo:UBERON_0000010 a rdfs:Class ;
rdfs:label "peripheral nervous system" ;
rdfs:comment "A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:UBERON_0000926 a rdfs:Class ;
rdfs:label "mesoderm" ;
rdfs:comment "The middle germ layer of the embryo, between the endoderm and ectoderm." ;
rdfs:subClassOf obo:UBERON_0000923 .
obo:GO_1904751 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to nucleolus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900182 , obo:GO_1904749 .
obo:CHEBI_39158 a rdfs:Class ;
rdfs:label "(R)-trichostatic acid" ;
rdfs:subClassOf obo:CHEBI_39157 .
obo:GO_0044423 a rdfs:Class ;
rdfs:label "virion component" ;
rdfs:comment "Any constituent part of a virion, a complete fully infectious extracellular virus particle." ;
rdfs:subClassOf obo:GO_0005575 .
obo:GO_0060933 a rdfs:Class ;
rdfs:label "His-Purkinje system cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." ;
rdfs:subClassOf obo:GO_0048468 , obo:GO_0055006 .
obo:GO_1902864 a rdfs:Class ;
rdfs:label "negative regulation of embryonic camera-type eye development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0065007 , obo:GO_1902863 .
obo:PHIPO_0000150 a rdfs:Class ;
rdfs:label "increased DNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is increased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000145 .
obo:PR_P50283 a rdfs:Class ;
rdfs:label "T-cell antigen CD7 (mouse)" ;
rdfs:comment "A CD7 molecule that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001836 , obo:PR_000029032 .
obo:UBERON_0007123 a rdfs:Class ;
rdfs:label "pharyngeal pouch 2" ;
rdfs:comment "A pharyngeal puch that is between the pharyngeal arches 2 and 3." ;
rdfs:subClassOf obo:UBERON_0004117 .
obo:GO_0110122 a rdfs:Class ;
rdfs:label "myotube cell migration" ;
rdfs:comment "The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse." ;
rdfs:subClassOf obo:GO_0014812 , obo:GO_0016477 .
obo:GO_0003230 a rdfs:Class ;
rdfs:label "cardiac atrium development" ;
rdfs:comment "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." ;
rdfs:subClassOf obo:GO_0003205 , obo:GO_0048856 .
obo:PR_000005307 a rdfs:Class ;
rdfs:label "CCAAT/enhancer-binding protein alpha" ;
rdfs:comment "A protein that is a translation product of the human CEBPA gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_83686 a rdfs:Class ;
rdfs:label "(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol" ;
rdfs:comment "A member of the class of pyrimidines that is pyrimidin-5-ylmethanol in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 2-chlorophenyl group while the other is replaced by a 4-chlorophenyl group." ;
rdfs:subClassOf obo:CHEBI_26878 , obo:CHEBI_39447 , obo:CHEBI_83403 .
obo:CHEBI_22565 a rdfs:Class ;
rdfs:label "ansamycin" ;
rdfs:comment "A class of macrocyclic lactams that consist of an aromatic (phenyl or naphthyl) or quinonoid (benzoquinone or naphthoquinone) moiety that is bridged by an aliphatic chain." ;
rdfs:subClassOf obo:CHEBI_24995 , obo:CHEBI_26188 , obo:CHEBI_51026 .
obo:GO_0120008 a rdfs:Class ;
rdfs:label "positive regulation of glutamatergic neuron differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation." ;
rdfs:subClassOf obo:GO_0045666 , obo:GO_0065007 , obo:GO_0120006 .
obo:CHEBI_190303 a rdfs:Class ;
rdfs:label "inorganic potassium salt" ;
rdfs:comment "A potassium salt that lacks C-H bonds" ;
rdfs:subClassOf obo:CHEBI_167164 , obo:CHEBI_24839 , obo:CHEBI_26218 .
obo:NCBITaxon_8287 a rdfs:Class ;
rdfs:label "Sarcopterygii" ;
rdfs:subClassOf obo:NCBITaxon_117571 .
obo:GO_0099503 a rdfs:Class ;
rdfs:label "secretory vesicle" ;
rdfs:comment "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." ;
rdfs:subClassOf obo:GO_0031410 , obo:GO_0031982 .
obo:PHIPO_0000672 a rdfs:Class ;
rdfs:label "resistance to pentamidine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to pentamidine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0061109 a rdfs:Class ;
rdfs:label "dense core granule organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0033363 .
obo:PHIPO_0001011 a rdfs:Class ;
rdfs:label "normal transport"@en ;
rdfs:comment "A single organism cellular process phenotype observed in the vegetative growth phase of the life cycle in which transport is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000256 .
obo:UBERON_0035553 a rdfs:Class ;
rdfs:label "left cardiac chamber" ;
rdfs:comment "Any chamber of the left side of the heart." ;
rdfs:subClassOf obo:UBERON_0004151 , obo:UBERON_0015212 .
obo:PHIPO_0000503 a rdfs:Class ;
rdfs:label "deoxynivalenol absent from cell"@en ;
rdfs:comment "A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is too low to detect." ;
rdfs:subClassOf obo:PHIPO_0001034 .
obo:CL_0000133 a rdfs:Class ;
rdfs:label "neurectodermal cell" ;
rdfs:comment "Ectoderm destined to be nervous tissue." ;
rdfs:subClassOf obo:CL_0000221 .
obo:UBERON_0015783 a rdfs:Class ;
rdfs:label "smooth muscle layer in fatty layer of subcutaneous tissue" ;
rdfs:comment "A smooth muscle tissue that is part of a hypodermis." ;
rdfs:subClassOf obo:UBERON_0001135 .
obo:PHIPO_0000058 a rdfs:Class ;
rdfs:label "obsolete normal timing in production of sexual spores" .
obo:GO_0140014 a rdfs:Class ;
rdfs:label "mitotic nuclear division" ;
rdfs:comment "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." ;
rdfs:subClassOf obo:GO_0000280 , obo:GO_1903047 .
obo:CHEBI_58953 a rdfs:Class ;
rdfs:label "saturated fatty acid anion" ;
rdfs:comment "Any fatty acid anion in which there is no C‒C unsaturation." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:PHIPO_0000281 a rdfs:Class ;
rdfs:label "obsolete stature phenotype" .
a rdfs:Class ;
rdfs:label "Epithalamus" ;
rdfs:subClassOf , obo:UBERON_0001899 .
obo:GO_0060560 a rdfs:Class ;
rdfs:label "developmental growth involved in morphogenesis" ;
rdfs:comment "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." ;
rdfs:subClassOf obo:GO_0048589 .
obo:GO_0006714 a rdfs:Class ;
rdfs:label "sesquiterpenoid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units." ;
rdfs:subClassOf obo:GO_0006721 .
obo:GO_0002705 a rdfs:Class ;
rdfs:label "positive regulation of leukocyte mediated immunity" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity." ;
rdfs:subClassOf obo:GO_0002699 , obo:GO_0002703 , obo:GO_0065007 .
obo:CHEBI_37699 a rdfs:Class ;
rdfs:label "protein kinase inhibitor" ;
rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases." ;
rdfs:subClassOf obo:CHEBI_76668 .
obo:GO_0070483 a rdfs:Class ;
rdfs:label "detection of hypoxia" ;
rdfs:comment "The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." ;
rdfs:subClassOf obo:GO_0001666 , obo:GO_0003032 .
obo:GO_0022011 a rdfs:Class ;
rdfs:label "myelination in peripheral nervous system" ;
rdfs:comment "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." ;
rdfs:subClassOf obo:GO_0032292 , obo:GO_0042552 .
obo:PR_000001483 a rdfs:Class ;
rdfs:label "low affinity immunoglobulin gamma Fc region receptor III" ;
rdfs:comment "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr3 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001355 .
obo:GO_0032228 a rdfs:Class ;
rdfs:label "regulation of synaptic transmission, GABAergic" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 .
obo:GO_0001963 a rdfs:Class ;
rdfs:label "synaptic transmission, dopaminergic" ;
rdfs:comment "The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ;
rdfs:subClassOf obo:GO_0007268 .
obo:CHEBI_36683 a rdfs:Class ;
rdfs:label "organochlorine compound" ;
rdfs:comment "An organochlorine compound is a compound containing at least one carbon-chlorine bond." ;
rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_23117 .
obo:PHIPO_0000077 a rdfs:Class ;
rdfs:label "abnormal sexual sporulation"@en ;
rdfs:comment "A reproductive phenotype where the process of sexual sporulation, the formation of spores from the products of meiosis, is abnormal (GO:0034293)." ;
rdfs:subClassOf obo:PHIPO_0000048 .
obo:GO_0032501 a rdfs:Class ;
rdfs:label "multicellular organismal process" ;
rdfs:comment "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_0045132 a rdfs:Class ;
rdfs:label "meiotic chromosome segregation" ;
rdfs:comment "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0098813 , obo:GO_1903046 .
obo:GO_0002523 a rdfs:Class ;
rdfs:label "leukocyte migration involved in inflammatory response" ;
rdfs:comment "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response." ;
rdfs:subClassOf obo:GO_0050900 .
obo:GO_0007422 a rdfs:Class ;
rdfs:label "peripheral nervous system development" ;
rdfs:comment "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:GO_0031252 a rdfs:Class ;
rdfs:label "cell leading edge" ;
rdfs:comment "The area of a motile cell closest to the direction of movement." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_44137 a rdfs:Class ;
rdfs:label "tiamulin" ;
rdfs:comment "A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) for the treatment of swine dysentery caused by Serpulina hyodysenteriae." ;
rdfs:subClassOf obo:CHEBI_16385 , obo:CHEBI_33308 , obo:CHEBI_35681 , obo:CHEBI_38032 , obo:CHEBI_3992 , obo:CHEBI_50996 , obo:CHEBI_52557 , obo:CHEBI_72588 .
obo:GO_1902721 a rdfs:Class ;
rdfs:label "negative regulation of prolactin secretion" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion." ;
rdfs:subClassOf obo:GO_0050709 , obo:GO_0065007 , obo:GO_0090278 .
obo:CHEBI_24897 a rdfs:Class ;
rdfs:label "isoindoles" ;
rdfs:subClassOf obo:CHEBI_22728 .
obo:CHEBI_25061 a rdfs:Class ;
rdfs:label "lipopeptide antibiotic" ;
rdfs:subClassOf obo:CHEBI_25903 , obo:CHEBI_46895 .
obo:GO_0140354 a rdfs:Class ;
rdfs:label "lipid import into cell" ;
rdfs:comment "The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0006869 .
a rdfs:Class ;
rdfs:label "Thalamus, polymodal association cortex related" ;
rdfs:subClassOf obo:BFO_0000004 .
obo:UBERON_2001053 a rdfs:Class ;
rdfs:label "future internal carotid artery" ;
rdfs:subClassOf obo:UBERON_0004573 .
obo:UBERON_0005383 a rdfs:Class ;
rdfs:label "caudate-putamen" ;
rdfs:comment "Regional part of telencephalon in some species, e.g., rodent, equivalent to the dorsal striatum (caudate nucleus and putamen). Unlike the dorsal striatum of primates, for example, the caudoputamen is not split into separate nuclei by the fibers of the internal capsule. Rather, the internal capsule splits into fiber bundles which course through the structure." ;
rdfs:subClassOf obo:UBERON_0011215 .
obo:CL_4310143 a rdfs:Class ;
rdfs:label "ZI-HTH GABA GABAergic interneuron (Primate)" ;
rdfs:comment "A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:ZI-HTH GABA." ;
rdfs:subClassOf obo:CL_0011005 .
obo:GO_0042330 a rdfs:Class ;
rdfs:label "taxis" ;
rdfs:comment "The directed movement of a motile cell or organism in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0040011 .
obo:CARO_0000000 a rdfs:Class ;
rdfs:label "anatomical entity" ;
rdfs:comment "A part of a multicellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a multicellular organism with granularity above the level of a protein complex." ;
rdfs:subClassOf obo:BFO_0000040 .
obo:GO_0002710 a rdfs:Class ;
rdfs:label "negative regulation of T cell mediated immunity" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity." ;
rdfs:subClassOf obo:GO_0002707 , obo:GO_0002709 , obo:GO_0002823 , obo:GO_0065007 .
obo:GO_0005881 a rdfs:Class ;
rdfs:label "cytoplasmic microtubule" ;
rdfs:comment "Any microtubule in the cytoplasm of a cell." ;
rdfs:subClassOf obo:GO_0005874 .
obo:UBERON_0007134 a rdfs:Class ;
rdfs:label "trunk ganglion" ;
rdfs:comment "Ganglion which is located in the trunk." ;
rdfs:subClassOf obo:UBERON_0000045 .
obo:GO_0015159 a rdfs:Class ;
rdfs:label "polysaccharide transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ;
rdfs:subClassOf obo:GO_0015144 , obo:GO_0022857 , obo:GO_0022884 .
obo:CHEBI_51276 a rdfs:Class ;
rdfs:label "thioureas" ;
rdfs:comment "Compounds of general formula RR'NC(=S)NR''R'''." ;
rdfs:subClassOf obo:CHEBI_50492 .
a rdfs:Class ;
rdfs:label "Arcuate hypothalamic nucleus" ;
rdfs:subClassOf , obo:UBERON_0001932 , obo:UBERON_0006331 .
obo:CHEBI_15693 a rdfs:Class ;
rdfs:label "aldose" ;
rdfs:comment "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n ≥ 2) and their intramolecular hemiacetals." ;
rdfs:subClassOf obo:CHEBI_35381 .
obo:CHEBI_26273 a rdfs:Class ;
rdfs:label "proline derivative" ;
rdfs:comment "An amino acid derivative resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of proline by a heteroatom. The definition normally excludes peptides containing proline residues." ;
rdfs:subClassOf obo:CHEBI_83821 .
obo:CHEBI_36902 a rdfs:Class ;
rdfs:label "chalcogen hydride" ;
rdfs:subClassOf obo:CHEBI_33242 , obo:CHEBI_33304 .
obo:CL_4033049 a rdfs:Class ;
rdfs:label "taste receptor cell of tongue" ;
rdfs:comment "A taste receptor cell that is part of a taste bud of a tongue." ;
rdfs:subClassOf obo:CL_0000209 , obo:CL_0002319 .
obo:UBERON_0012504 a rdfs:Class ;
rdfs:label "adventitia of esophagus" ;
rdfs:comment "An adventitia that is part of a esophagus." ;
rdfs:subClassOf obo:UBERON_0005742 .
obo:CHEBI_48121 a rdfs:Class ;
rdfs:label "polyene" ;
rdfs:comment "An olefin that contains more than one carbon-carbon double bond." ;
rdfs:subClassOf obo:CHEBI_33641 .
obo:GO_0010454 a rdfs:Class ;
rdfs:label "negative regulation of cell fate commitment" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ;
rdfs:subClassOf obo:GO_0010453 , obo:GO_0045596 , obo:GO_0065007 .
obo:UBERON_0012274 a rdfs:Class ;
rdfs:label "columnar epithelium" ;
rdfs:comment "An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified]." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0051785 a rdfs:Class ;
rdfs:label "positive regulation of nuclear division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0051783 , obo:GO_0065007 .
obo:GO_0043264 a rdfs:Class ;
rdfs:label "extracellular membraneless organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." ;
rdfs:subClassOf obo:GO_0043228 , obo:GO_0043230 .
obo:GO_1905455 a rdfs:Class ;
rdfs:label "positive regulation of myeloid progenitor cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901534 , obo:GO_1905453 .
obo:CHEBI_35727 a rdfs:Class ;
rdfs:label "triazoles" ;
rdfs:comment "An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms." ;
rdfs:subClassOf obo:CHEBI_68452 .
obo:UBERON_0003406 a rdfs:Class ;
rdfs:label "cartilage of respiratory system" ;
rdfs:comment "A cartilage element that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0007844 .
obo:UBERON_0000104 a rdfs:Class ;
rdfs:label "life cycle" ;
rdfs:comment "An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism." ;
rdfs:subClassOf obo:BFO_0000015 , obo:UBERON_0000000 .
obo:UBERON_0003729 a rdfs:Class ;
rdfs:label "mouth mucosa" ;
rdfs:comment "A mucous membrane that lines the mouth." ;
rdfs:subClassOf obo:UBERON_0000344 .
obo:PHIPO_0001307 a rdfs:Class ;
rdfs:label "sensitive to non-ionic osmotic stress"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to a non-ionic osmotic stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide." ;
rdfs:subClassOf obo:PHIPO_0001303 .
obo:PHIPO_0001091 a rdfs:Class ;
rdfs:label "abolished chitinase activity"@en ;
rdfs:comment "A single species molecular function phenotype in which a chitinase activity is absent." ;
rdfs:subClassOf obo:PHIPO_0000435 .
obo:PHIPO_0001151 a rdfs:Class ;
rdfs:label "normal host size during pathogen invasion"@en ;
rdfs:comment "A host morphology phenotype where the size of the host is normal (indistinguishable from wild type) during pathogen invasion." ;
rdfs:subClassOf obo:PHIPO_0001005 .
obo:PHIPO_0000558 a rdfs:Class ;
rdfs:label "resistance to benzylpenicillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to benzylpenicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:UBERON_0005423 a rdfs:Class ;
rdfs:label "developing anatomical structure" ;
rdfs:subClassOf obo:UBERON_0000001 .
obo:CL_0000107 a rdfs:Class ;
rdfs:label "autonomic neuron" ;
rdfs:comment "A neuron whose cell body is within an autonomic ganglion." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000032 .
obo:PHIPO_0001326 a rdfs:Class ;
rdfs:label "normal growth on prochloraz"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to prochloraz (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_23403 a rdfs:Class ;
rdfs:label "coumarins" ;
rdfs:subClassOf obo:CHEBI_26004 , obo:CHEBI_38445 .
obo:GO_1905461 a rdfs:Class ;
rdfs:label "positive regulation of vascular associated smooth muscle cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." ;
rdfs:subClassOf obo:GO_0034393 , obo:GO_0065007 , obo:GO_1905459 .
obo:CL_0000566 a rdfs:Class ;
rdfs:label "angioblastic mesenchymal cell" ;
rdfs:comment "A mesenchymal stem cell capable of developing into blood vessel endothelium." ;
rdfs:subClassOf obo:CL_0000134 , obo:CL_0011026 .
obo:CHEBI_32876 a rdfs:Class ;
rdfs:label "tertiary amine" ;
rdfs:comment "A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups." ;
rdfs:subClassOf obo:CHEBI_32952 , obo:CHEBI_50996 .
obo:GO_0044403 a rdfs:Class ;
rdfs:label "symbiosis, encompassing mutualism through parasitism" ;
rdfs:comment "An interaction between two organisms living together in more or less intimate association. Microscopic symbionts are often referred to as endosymbionts. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs." ;
rdfs:subClassOf obo:GO_0044419 , obo:GO_0051704 .
obo:CHEBI_33338 a rdfs:Class ;
rdfs:label "aryl group" ;
rdfs:comment "A group derived from an arene by removal of a hydrogen atom from a ring carbon atom." ;
rdfs:subClassOf obo:CHEBI_33248 .
obo:CHEBI_24471 a rdfs:Class ;
rdfs:label "halogen molecular entity" ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:GO_0030219 a rdfs:Class ;
rdfs:label "megakaryocyte differentiation" ;
rdfs:comment "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte." ;
rdfs:subClassOf obo:GO_0030099 , obo:GO_0030154 .
obo:CHEBI_39447 a rdfs:Class ;
rdfs:label "pyrimidines" ;
rdfs:comment "Any compound having a pyrimidine as part of its structure." ;
rdfs:subClassOf obo:CHEBI_38313 .
obo:GO_1902494 a rdfs:Class ;
rdfs:label "catalytic complex" ;
rdfs:comment "A protein complex which is capable of catalytic activity." ;
rdfs:subClassOf obo:GO_0032991 .
obo:CL_4023154 a rdfs:Class ;
rdfs:label "myelinating glial cell" ;
rdfs:comment "A glial cell that myelinates axonal processes." ;
rdfs:subClassOf obo:CL_0000125 .
obo:UBERON_0002376 a rdfs:Class ;
rdfs:label "cranial muscle" ;
rdfs:comment "Any skeletal muscle that is part of the head region." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0010959 , obo:UBERON_0014892 .
obo:UBERON_0003830 a rdfs:Class ;
rdfs:label "thoracic segment muscle" ;
rdfs:comment "Any muscle organ that is part of a thorax [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001774 , obo:UBERON_0005181 , obo:UBERON_0014892 .
obo:GO_1902065 a rdfs:Class ;
rdfs:label "response to L-glutamate" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus." ;
rdfs:subClassOf obo:GO_0043200 , obo:GO_0050896 , obo:GO_1901698 , obo:GO_1901700 .
obo:GO_1903532 a rdfs:Class ;
rdfs:label "positive regulation of secretion by cell" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of secretion by cell." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0051047 , obo:GO_0065007 , obo:GO_1903530 .
obo:CHEBI_58007 a rdfs:Class ;
rdfs:label "streptomycin(3+)" ;
rdfs:comment "Trication of streptomycin arising from protonation of the guanidino and secondary amino groups." ;
rdfs:subClassOf obo:CHEBI_60251 .
obo:GO_0006839 a rdfs:Class ;
rdfs:label "mitochondrial transport" ;
rdfs:comment "Transport of substances into, out of or within a mitochondrion." ;
rdfs:subClassOf obo:GO_0046907 .
obo:GO_1904035 a rdfs:Class ;
rdfs:label "regulation of epithelial cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:UBERON_0004573 a rdfs:Class ;
rdfs:label "systemic artery" ;
rdfs:comment "An artery of the systemic circulation, which is the part of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:UBERON_0001781 a rdfs:Class ;
rdfs:label "layer of retina" ;
rdfs:comment "Any of the layers that make up the retina[MP]." ;
rdfs:subClassOf obo:UBERON_0022303 .
obo:GO_0050789 a rdfs:Class ;
rdfs:label "regulation of biological process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ;
rdfs:subClassOf obo:GO_0065007 .
obo:GO_0032878 a rdfs:Class ;
rdfs:label "regulation of establishment or maintenance of cell polarity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:PHIPO_0000042 a rdfs:Class ;
rdfs:label "obsolete abnormal motility phenotype" .
obo:CL_4052030 a rdfs:Class ;
rdfs:label "adventitial fibroblast" ;
rdfs:comment "A fibroblast of the adventitia of a blood vessel. This cell contributes to vascular homeostasis, remodeling, and inflammation by producing extracellular matrix components, cytokines, and growth factors. Adventitial fibroblast can transition into an activated state during injury or disease, marked by increased proliferation, migration, matrix deposition, and contractile protein expression" ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0000151 , obo:CL_0002503 .
obo:PHIPO_0001162 a rdfs:Class ;
rdfs:label "obsolete host reproductive phenotype induced by pathogen" ;
rdfs:comment "A pathogen host interaction phenotype which affects the host reproductive process within the host when a pathogen is present. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003)." .
obo:UBERON_0007037 a rdfs:Class ;
rdfs:label "mechanosensory system" ;
rdfs:subClassOf obo:UBERON_0001032 .
obo:PHIPO_0001061 a rdfs:Class ;
rdfs:label "decreased RNA level"@en ;
rdfs:comment "A singe species cell phenotype in which the amount of RNA measured in a cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." ;
rdfs:subClassOf obo:PHIPO_0001035 , obo:PHIPO_0001060 .
obo:UBERON_0003479 a rdfs:Class ;
rdfs:label "thoracic cavity vein" ;
rdfs:comment "A vein that is part of a thoracic cavity [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0003519 .
obo:CL_0000065 a rdfs:Class ;
rdfs:label "ependymal cell" ;
rdfs:comment "A neuroepithelial glial cell, derived from a radial glial cell originating from the neuroectoderm, lines the ventricles of the brain and the central canal of the spinal cord. This cell is characterized by the presence of cilia on its apical surface, which can be motile or non-motile." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0000067 , obo:CL_0000125 , obo:CL_0000710 .
obo:GO_0042592 a rdfs:Class ;
rdfs:label "homeostatic process" ;
rdfs:comment "Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CL_0002548 a rdfs:Class ;
rdfs:label "fibroblast of cardiac tissue" ;
rdfs:comment "A fibroblast that is part of the heart." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0002494 .
obo:CHEBI_33958 a rdfs:Class ;
rdfs:label "halide salt" ;
rdfs:subClassOf obo:CHEBI_24866 , obo:CHEBI_37578 .
obo:CHEBI_26144 a rdfs:Class ;
rdfs:label "piperazines" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:PHIPO_0000107 a rdfs:Class ;
rdfs:label "decreased number of penetration structure"@en ;
rdfs:comment "A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration stuctures are decreased when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000032 .
obo:GO_0051646 a rdfs:Class ;
rdfs:label "mitochondrion localization" ;
rdfs:comment "Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051640 .
obo:UBERON_0002078 a rdfs:Class ;
rdfs:label "right cardiac atrium" ;
rdfs:comment "A cardiac atrium that is in the right side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve." ;
rdfs:subClassOf obo:UBERON_0002081 , obo:UBERON_0035554 .
obo:BSPO_0000121 a rdf:Property ;
rdfs:range .
obo:GO_0007269 a rdfs:Class ;
rdfs:label "neurotransmitter secretion" ;
rdfs:comment "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." ;
rdfs:subClassOf obo:GO_0006836 , obo:GO_0051649 , obo:GO_0099643 .
obo:GO_1900117 a rdfs:Class ;
rdfs:label "regulation of execution phase of apoptosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of execution phase of apoptosis." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:PR_000001892 a rdfs:Class ;
rdfs:label "CD33 molecule" ;
rdfs:comment "A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_64228 a rdfs:Class ;
rdfs:label "tunicamycin A0" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 11-methyldodec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:GO_0002443 a rdfs:Class ;
rdfs:label "leukocyte mediated immunity" ;
rdfs:comment "Any process involved in the carrying out of an immune response by a leukocyte." ;
rdfs:subClassOf obo:GO_0002252 , obo:GO_0002376 .
obo:GO_0015175 a rdfs:Class ;
rdfs:label "neutral L-amino acid transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of neutral L-amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3." ;
rdfs:subClassOf obo:GO_0015171 .
obo:UBERON_0003381 a rdfs:Class ;
rdfs:label "cardiac muscle of right ventricle" ;
rdfs:comment "A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001133 , obo:UBERON_0018649 .
obo:CHEBI_50177 a rdfs:Class ;
rdfs:label "dermatologic drug" ;
rdfs:comment "A drug used to treat or prevent skin disorders or for the routine care of skin." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:CHEBI_38216 a rdfs:Class ;
rdfs:label "3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate)" ;
rdfs:subClassOf obo:CHEBI_25471 .
obo:CL_4307134 a rdfs:Class ;
rdfs:label "BAM NN_1 Fos border associated macrophage (Mmus)" ;
rdfs:comment "A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Pf4 (Mmus), Fos (Mmus). It is distinguished from other BAM NN cells by expression of Fos. These cells are located in the Isocortex, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5314 BAM NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301625 .
obo:UBERON_0036291 a rdfs:Class ;
rdfs:label "myocardium of anterior wall of right ventricle" ;
rdfs:subClassOf obo:UBERON_0002349 , obo:UBERON_0006567 .
obo:PHIPO_0000047 a rdfs:Class ;
rdfs:label "abnormal asexual reproduction"@en ;
rdfs:comment "A single species phenotype where the asexual reproduction process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is abnormal (GO:0019954)." ;
rdfs:subClassOf obo:PHIPO_0000043 .
obo:GO_0045843 a rdfs:Class ;
rdfs:label "negative regulation of striated muscle tissue development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development." ;
rdfs:subClassOf obo:GO_0016202 , obo:GO_0048635 , obo:GO_0065007 , obo:GO_1901862 .
obo:CHEBI_15841 a rdfs:Class ;
rdfs:label "polypeptide" ;
rdfs:comment "A peptide containing ten or more amino acid residues." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_33839 .
obo:PHIPO_0001128 a rdfs:Class ;
rdfs:label "effector-mediated suppression of host PAMP-triggered immunity present"@en ;
rdfs:comment "A cell signaling pathway phenotype where the molecular pattern-induced host innate immune response signaling pathway is suppressed by a pathogen. (GO:0052034)" ;
rdfs:subClassOf obo:PHIPO_0001176 .
obo:GO_1901698 a rdfs:Class ;
rdfs:label "response to nitrogen compound" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." ;
rdfs:subClassOf obo:GO_0042221 , obo:GO_0050896 .
obo:UBERON_0002406 a rdfs:Class ;
rdfs:label "pericardial sac" ;
rdfs:comment "A double-walled sac containing the heart and the roots of the great vessels." ;
rdfs:subClassOf obo:UBERON_0005181 , obo:UBERON_0005906 .
obo:GO_0043588 a rdfs:Class ;
rdfs:label "skin development" ;
rdfs:comment "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:GO_0033363 a rdfs:Class ;
rdfs:label "secretory granule organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0016050 .
obo:GO_0001886 a rdfs:Class ;
rdfs:label "endothelial cell morphogenesis" ;
rdfs:comment "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell." ;
rdfs:subClassOf obo:GO_0003382 , obo:GO_0009653 .
obo:PHIPO_0000885 a rdfs:Class ;
rdfs:label "sensitive to novobiocin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to novobiocin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0014059 a rdfs:Class ;
rdfs:label "regulation of dopamine secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of dopamine." ;
rdfs:subClassOf obo:GO_0050433 , obo:GO_0065007 .
obo:PHIPO_0001315 a rdfs:Class ;
rdfs:label "normal growth on cymoxanil"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to cymoxanil (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0019955 a rdfs:Class ;
rdfs:label "cytokine binding" ;
rdfs:comment "Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity." ;
rdfs:subClassOf obo:GO_0005515 .
obo:GO_0060439 a rdfs:Class ;
rdfs:label "trachea morphogenesis" ;
rdfs:comment "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:GO_0019751 a rdfs:Class ;
rdfs:label "polyol metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms." ;
rdfs:subClassOf obo:GO_0006066 .
obo:GO_0098904 a rdfs:Class ;
rdfs:label "regulation of AV node cell action potential" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0050789 , obo:GO_0098901 .
obo:CHEBI_48706 a rdfs:Class ;
rdfs:label "antagonist" ;
rdfs:comment "Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:PHIPO_0001343 a rdfs:Class ;
rdfs:label "sensitive to triflumizole" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to triflumizole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0032225 a rdfs:Class ;
rdfs:label "regulation of synaptic transmission, dopaminergic" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 .
obo:NCBITaxon_3701030 a rdfs:Class ;
rdfs:label "Allotriocarida" ;
rdfs:subClassOf obo:NCBITaxon_3701028 .
obo:CHEBI_27096 a rdfs:Class ;
rdfs:label "trichlorobenzene" ;
rdfs:comment "Any member of the class of chlorobenzenes carrying three chloro substituents at unspecified positions." ;
rdfs:subClassOf obo:CHEBI_23132 .
obo:GO_0034502 a rdfs:Class ;
rdfs:label "protein localization to chromosome" ;
rdfs:comment "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033365 .
obo:GO_0002684 a rdfs:Class ;
rdfs:label "positive regulation of immune system process" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of an immune system process." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0048518 , obo:GO_0065007 .
obo:PHIPO_0000429 a rdfs:Class ;
rdfs:label "obsolete normal pathogen and host chitinases bind pathogen chitin and chitin fragments" .
obo:UBERON_0001534 a rdfs:Class ;
rdfs:label "right subclavian artery" ;
rdfs:comment "The subclavian artery that supplies the right pectoral appendage." ;
rdfs:subClassOf obo:UBERON_0001533 , obo:UBERON_0015212 .
obo:GO_0048710 a rdfs:Class ;
rdfs:label "regulation of astrocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of astrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045685 , obo:GO_0065007 .
obo:GO_0051967 a rdfs:Class ;
rdfs:label "negative regulation of synaptic transmission, glutamatergic" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." ;
rdfs:subClassOf obo:GO_0050805 , obo:GO_0051966 , obo:GO_0065007 .
obo:GO_0030030 a rdfs:Class ;
rdfs:label "cell projection organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." ;
rdfs:subClassOf obo:GO_0016043 .
obo:UBERON_0007281 a rdfs:Class ;
rdfs:label "presumptive midbrain hindbrain boundary" ;
rdfs:comment "Embryonic structure that gives rise to the midbrain hindbrain boundary." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:CHEBI_37247 a rdfs:Class ;
rdfs:label "elemental potassium" ;
rdfs:subClassOf obo:CHEBI_26217 .
obo:CHEBI_33240 a rdfs:Class ;
rdfs:label "coordination entity" ;
rdfs:comment "An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands)." ;
rdfs:subClassOf obo:CHEBI_37577 .
obo:UBERON_0000204 a rdfs:Class ;
rdfs:label "ventral part of telencephalon" ;
rdfs:comment "Ventral part (base region) of the telencephalon." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_0017145 a rdfs:Class ;
rdfs:label "stem cell division" ;
rdfs:comment "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." ;
rdfs:subClassOf obo:GO_0051301 .
obo:CHEBI_25830 a rdfs:Class ;
rdfs:label "p-quinones" ;
rdfs:comment "A quinone in which the two oxo groups of the quinone are located para to each other on the 6-membered quinonoid ring." ;
rdfs:subClassOf obo:CHEBI_36141 .
obo:UBERON_0013754 a rdfs:Class ;
rdfs:label "integumentary system layer" ;
rdfs:comment "An organ component layer that is part of a integumental system." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:UBERON_0002139 a rdfs:Class ;
rdfs:label "subcommissural organ" ;
rdfs:comment "The subcommissural organ is a circumventricular organ consisting of ependymal and hypendymal cells which secrete SCO-spondin[WP,partially vetted]." ;
rdfs:subClassOf obo:UBERON_0010134 .
obo:UBERON_0010031 a rdfs:Class ;
rdfs:label "6th arch mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a pharyngeal arch 6." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0009494 .
obo:GO_0050774 a rdfs:Class ;
rdfs:label "negative regulation of dendrite morphogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis." ;
rdfs:subClassOf obo:GO_0031345 , obo:GO_0048814 , obo:GO_0050768 , obo:GO_0065007 .
obo:CL_0000166 a rdfs:Class ;
rdfs:label "chromaffin cell" ;
rdfs:comment "A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system." ;
rdfs:subClassOf obo:CL_0000029 , obo:CL_0000568 .
obo:UBERON_0002217 a rdfs:Class ;
rdfs:label "synovial joint" ;
rdfs:comment "Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000982 .
obo:GO_2000978 a rdfs:Class ;
rdfs:label "negative regulation of forebrain neuron differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation." ;
rdfs:subClassOf obo:GO_0045665 , obo:GO_0065007 , obo:GO_2000977 .
obo:CHEBI_36586 a rdfs:Class ;
rdfs:label "carbonyl compound" ;
rdfs:comment "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." ;
rdfs:subClassOf obo:CHEBI_36587 , obo:CHEBI_36963 .
obo:CHEBI_36361 a rdfs:Class ;
rdfs:label "phosphorous acid" ;
rdfs:subClassOf obo:CHEBI_33457 .
obo:GO_2000672 a rdfs:Class ;
rdfs:label "negative regulation of motor neuron apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process." ;
rdfs:subClassOf obo:GO_0043524 , obo:GO_0065007 , obo:GO_2000671 .
obo:CHEBI_33280 a rdfs:Class ;
rdfs:label "molecular messenger" ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_83293 a rdfs:Class ;
rdfs:label "(R)-fenpropidin" ;
rdfs:comment "A 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine that has R configuration." ;
rdfs:subClassOf obo:CHEBI_83291 .
obo:CHEBI_50525 a rdfs:Class ;
rdfs:label "phenolate anion" ;
rdfs:comment "An organic anion arising from deprotonation of the OH function of a phenol compound." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:GO_1901627 a rdfs:Class ;
rdfs:label "negative regulation of postsynaptic membrane organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901626 , obo:GO_1905809 .
obo:PHIPO_0000085 a rdfs:Class ;
rdfs:label "obsolete decreased asexual spore motility" .
obo:GO_0061889 a rdfs:Class ;
rdfs:label "negative regulation of astrocyte activation" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of astrocyte activation." ;
rdfs:subClassOf obo:GO_0048712 , obo:GO_0050866 , obo:GO_0061888 , obo:GO_0065007 , obo:GO_0150079 .
obo:UBERON_0016527 a rdfs:Class ;
rdfs:label "white matter of cerebral lobe" ;
rdfs:subClassOf obo:UBERON_0002437 .
obo:BSPO_0000107 a rdf:Property ;
rdfs:range .
obo:PHIPO_0000026 a rdfs:Class ;
rdfs:label "obsolete normal penetration" ;
rdfs:comment "A pathogen phenotype indicating that the pathogen is able to penetrate a given experimental substance/membrane in the same manner as the wild-type." .
obo:GO_0022033 a rdfs:Class ;
rdfs:label "telencephalon microglial cell migration" ;
rdfs:comment "The orderly movement of microglial cells through the telencephalon." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0022030 .
obo:CHEBI_140345 a rdfs:Class ;
rdfs:label "hydroxy polyunsaturated fatty acid" ;
rdfs:comment "Any polyunsaturated fatty acid carrying one or more hydroxy substituents." ;
rdfs:subClassOf obo:CHEBI_24654 , obo:CHEBI_26208 .
obo:GO_0042103 a rdfs:Class ;
rdfs:label "positive regulation of T cell homeostatic proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of resting T cell proliferation." ;
rdfs:subClassOf obo:GO_0042102 , obo:GO_0046013 , obo:GO_0065007 .
obo:UBERON_0002425 a rdfs:Class ;
rdfs:label "visceral serous pericardium" ;
rdfs:comment "Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]." ;
rdfs:subClassOf obo:UBERON_0022350 .
obo:GO_0006544 a rdfs:Class ;
rdfs:label "glycine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving glycine, aminoethanoic acid." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0170039 .
obo:UBERON_0001893 a rdfs:Class ;
rdfs:label "telencephalon" ;
rdfs:comment "Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres." ;
rdfs:subClassOf obo:UBERON_0002616 , obo:UBERON_0004121 .
obo:CL_4301611 a rdfs:Class ;
rdfs:label "commited oligodendrocyte precursor (Mmus)" ;
rdfs:comment "A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bmp4 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1181 COP NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4023059 , obo:CL_4300367 .
obo:UBERON_0001135 a rdfs:Class ;
rdfs:label "smooth muscle tissue" ;
rdfs:comment "Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]." ;
rdfs:subClassOf obo:UBERON_0002385 .
obo:GO_0030203 a rdfs:Class ;
rdfs:label "glycosaminoglycan metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving glycosaminoglycans, any of a group of linear polysaccharides composed of repeating disaccharide units." ;
rdfs:subClassOf obo:GO_0006022 , obo:GO_0008152 .
obo:UBERON_0000965 a rdfs:Class ;
rdfs:label "lens of camera-type eye" ;
rdfs:comment "A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina." ;
rdfs:subClassOf obo:UBERON_0005389 .
obo:GO_1904414 a rdfs:Class ;
rdfs:label "positive regulation of cardiac ventricle development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac ventricle development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1904412 .
obo:GO_0007439 a rdfs:Class ;
rdfs:label "ectodermal digestive tract development" ;
rdfs:comment "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048729 .
obo:UBERON_0005090 a rdfs:Class ;
rdfs:label "muscle structure" ;
rdfs:comment "Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0001957 a rdfs:Class ;
rdfs:label "intramembranous ossification" ;
rdfs:comment "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells." ;
rdfs:subClassOf obo:GO_0036072 .
obo:GO_0042644 a rdfs:Class ;
rdfs:label "chloroplast nucleoid" ;
rdfs:comment "The region of a chloroplast to which the DNA is confined." ;
rdfs:subClassOf obo:GO_0009295 , obo:GO_0042646 .
obo:GO_1903379 a rdfs:Class ;
rdfs:label "regulation of mitotic chromosome condensation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0060623 , obo:GO_0065007 .
obo:PHIPO_0001210 a rdfs:Class ;
rdfs:label "normal hyphal growth"@en ;
rdfs:comment "An individual organism growth phenotype in which the size or extent of directional growth of hyphae is normal." ;
rdfs:subClassOf obo:PHIPO_0001214 .
obo:UBERON_0003615 a rdfs:Class ;
rdfs:label "lung elastic tissue" ;
rdfs:comment "Elastic tissue that is part of a lung [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000114 , obo:UBERON_0002521 , obo:UBERON_0003611 .
obo:GO_1905483 a rdfs:Class ;
rdfs:label "regulation of motor neuron migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of motor neuron migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2001222 .
obo:GO_0009067 a rdfs:Class ;
rdfs:label "aspartate family amino acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of L-aspartate or any of the amino acids synthesised from it (L-asparagine, L-lysine, L-methionine, L-threonine and L-isoleucine)." ;
rdfs:subClassOf obo:GO_0170034 , obo:GO_0170038 .
obo:GO_0060125 a rdfs:Class ;
rdfs:label "negative regulation of growth hormone secretion" ;
rdfs:comment "Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell." ;
rdfs:subClassOf obo:GO_0060123 , obo:GO_0065007 , obo:GO_0090278 .
obo:CHEBI_37661 a rdfs:Class ;
rdfs:label "glucopyranose" ;
rdfs:subClassOf obo:CHEBI_17234 .
obo:PHIPO_0000007 a rdfs:Class ;
rdfs:label "obsolete functional pathogen effector absent" ;
rdfs:comment "A phenotype where the ability of a pathogen effector to produce an infectious disease is absent." .
obo:GO_0005765 a rdfs:Class ;
rdfs:label "lysosomal membrane" ;
rdfs:comment "The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0098852 .
obo:GO_0030262 a rdfs:Class ;
rdfs:label "apoptotic nuclear changes" ;
rdfs:comment "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis." ;
rdfs:subClassOf obo:GO_0006921 .
obo:GO_0070830 a rdfs:Class ;
rdfs:label "bicellular tight junction assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0120192 .
obo:UBERON_0000115 a rdfs:Class ;
rdfs:label "lung epithelium" ;
rdfs:comment "The epithelial layer of the lung." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004815 .
obo:GO_1905065 a rdfs:Class ;
rdfs:label "positive regulation of vascular associated smooth muscle cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051152 , obo:GO_0065007 , obo:GO_1905063 .
obo:PHIPO_0000293 a rdfs:Class ;
rdfs:label "obsolete abnormal organism morphology phenotype" .
obo:CHEBI_35785 a rdfs:Class ;
rdfs:label "sphingoid" ;
rdfs:comment "Sphinganine, its homologs and stereoisomers, and the hydroxy and unsaturated derivatives of these compounds." ;
rdfs:subClassOf obo:CHEBI_26739 .
obo:PR_000007857 a rdfs:Class ;
rdfs:label "erythroid transcription factor" ;
rdfs:comment "A protein that is a translation product of the human GATA1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_36757 a rdfs:Class ;
rdfs:label "farnesane sesquiterpenoid" ;
rdfs:subClassOf obo:CHEBI_26658 .
obo:UBERON_0001739 a rdfs:Class ;
rdfs:label "laryngeal cartilage" ;
rdfs:comment "The cartilaginous structures that support the larynx." ;
rdfs:subClassOf obo:UBERON_0003406 , obo:UBERON_0007844 , obo:UBERON_0011004 .
obo:GO_0140513 a rdfs:Class ;
rdfs:label "nuclear protein-containing complex" ;
rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus." ;
rdfs:subClassOf obo:GO_0032991 .
obo:UBERON_0009580 a rdfs:Class ;
rdfs:label "diencephalon mantle layer" ;
rdfs:subClassOf obo:UBERON_0004061 .
obo:UBERON_0005181 a rdfs:Class ;
rdfs:label "thoracic segment organ" ;
rdfs:comment "An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0005177 .
obo:CHEBI_5195 a rdfs:Class ;
rdfs:label "furazolidone" ;
rdfs:comment "A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera." ;
rdfs:subClassOf obo:CHEBI_38329 , obo:CHEBI_87230 .
obo:CHEBI_33575 a rdfs:Class ;
rdfs:label "carboxylic acid" ;
rdfs:comment "A carbon oxoacid acid carrying at least one ‒C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." ;
rdfs:subClassOf obo:CHEBI_35605 , obo:CHEBI_36586 , obo:CHEBI_64709 .
obo:PHIPO_0001304 a rdfs:Class ;
rdfs:label "resistance to salt stress"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to a salt stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die)." ;
rdfs:subClassOf obo:PHIPO_0001302 .
obo:GO_0032276 a rdfs:Class ;
rdfs:label "regulation of gonadotropin secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin." ;
rdfs:subClassOf obo:GO_0044060 , obo:GO_0046883 , obo:GO_0065007 .
obo:GO_0120193 a rdfs:Class ;
rdfs:label "tight junction organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0045216 .
obo:GO_0003197 a rdfs:Class ;
rdfs:label "endocardial cushion development" ;
rdfs:comment "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060485 .
obo:CHEBI_60832 a rdfs:Class ;
rdfs:label "tubulin modulator" ;
rdfs:comment "Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:CL_0000219 a rdfs:Class ;
rdfs:label "motile cell" ;
rdfs:comment "A cell that moves by its own activities." ;
rdfs:subClassOf obo:CL_0000000 .
obo:UBERON_0016880 a rdfs:Class ;
rdfs:label "future nervous system" ;
rdfs:comment "Primordium that develops into the nervous system." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:RO_0002496 a rdf:Property ;
rdfs:label "existence starts during or after" ;
rdfs:comment "x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y)." ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002487 .
obo:GO_0072667 a rdfs:Class ;
rdfs:label "maintenance of protein location in vacuole" ;
rdfs:comment "Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0072595 .
obo:GO_0070445 a rdfs:Class ;
rdfs:label "regulation of oligodendrocyte progenitor proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000177 .
obo:GO_0021591 a rdfs:Class ;
rdfs:label "ventricular system development" ;
rdfs:comment "The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:PHIPO_0000694 a rdfs:Class ;
rdfs:label "resistance to daptomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to daptomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0030307 a rdfs:Class ;
rdfs:label "positive regulation of cell growth" ;
rdfs:comment "Any process that activates or increases the frequency, rate, extent or direction of cell growth." ;
rdfs:subClassOf obo:GO_0001558 , obo:GO_0045927 , obo:GO_0048522 , obo:GO_0065007 .
obo:UBERON_0003952 a rdfs:Class ;
rdfs:label "anterior stroma of cornea" ;
rdfs:comment "The anterior segment of the lamellated connective tissue layer of the cornea." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003566 .
obo:PHIPO_0000801 a rdfs:Class ;
rdfs:label "sensitive to amphotericin B"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to amphotericin B. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_52362 a rdfs:Class ;
rdfs:label "ortho-fused heteroarene" ;
rdfs:comment "An ortho-fused compound in which at least one of the rings contains at least one heteroatom." ;
rdfs:subClassOf obo:CHEBI_33637 , obo:CHEBI_38180 .
obo:GO_0061311 a rdfs:Class ;
rdfs:label "cell surface receptor signaling pathway involved in heart development" ;
rdfs:comment "The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time." ;
rdfs:subClassOf obo:GO_0007166 .
obo:CL_4030052 a rdfs:Class ;
rdfs:label "nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron" ;
rdfs:comment "A DRD2-expressing medium spiny neuron that is part of a nucleus accumbens shell or olfactory tubercle." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_1001474 .
obo:UBERON_0003897 a rdfs:Class ;
rdfs:label "axial muscle" ;
rdfs:comment "One of the skeletal muscles of the head and neck, spine, and ribs." ;
rdfs:subClassOf obo:UBERON_0014892 .
obo:CHEBI_49318 a rdfs:Class ;
rdfs:label "piperidine antibiotic" ;
rdfs:subClassOf obo:CHEBI_25558 , obo:CHEBI_26151 .
obo:UBERON_0001917 a rdfs:Class ;
rdfs:label "endothelium of artery" ;
rdfs:comment "An endothelium that is part of an artery [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0003915 , obo:UBERON_0004638 , obo:UBERON_0004700 .
obo:PATO_0001558 a rdfs:Class ;
rdfs:label "lacking processual parts" ;
rdfs:comment "A quality of a process inhering in a bearer by virtue of the bearer's lacking a processual part as specified by the additional entity." ;
rdfs:subClassOf obo:PATO_0001564 .
obo:CHEBI_29785 a rdfs:Class ;
rdfs:label "nitro group" ;
rdfs:subClassOf obo:CHEBI_33246 , obo:CHEBI_51144 .
obo:UBERON_0003869 a rdfs:Class ;
rdfs:label "presumptive ganglion" ;
rdfs:comment "A presumptive structure that has the potential to develop into a ganglion." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:UBERON_0007285 a rdfs:Class ;
rdfs:label "presumptive paraxial mesoderm" ;
rdfs:comment "The part of the blastula that has the potential to develop into a paraxial mesoderm." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:PHIPO_0000556 a rdfs:Class ;
rdfs:label "resistance to moxifloxacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to moxifloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_75606 a rdfs:Class ;
rdfs:label "hydroxamic acid ester" ;
rdfs:comment "A carboxamide that is a hydroxamic acid in which the hydrogen of the hydroxy group is replaced by an organyl group." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:GO_1905562 a rdfs:Class ;
rdfs:label "regulation of vascular endothelial cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation." ;
rdfs:subClassOf obo:GO_0001936 , obo:GO_0065007 .
obo:CHEBI_23366 a rdfs:Class ;
rdfs:label "compatible osmolytes" ;
rdfs:subClassOf obo:CHEBI_25728 .
obo:CHEBI_76662 a rdfs:Class ;
rdfs:label "EC 2.4.* (glycosyltransferase) inhibitor" ;
rdfs:comment "A transferase inhibitor inhibiting the action of a glycosyltransferase (EC 2.4.*.*)." ;
rdfs:subClassOf obo:CHEBI_71300 .
obo:GO_0006409 a rdfs:Class ;
rdfs:label "tRNA export from nucleus" ;
rdfs:comment "The directed movement of tRNA from the nucleus to the cytoplasm." ;
rdfs:subClassOf obo:GO_0006405 , obo:GO_0006810 , obo:GO_0051031 .
obo:CHEBI_28817 a rdfs:Class ;
rdfs:label "dodecane" ;
rdfs:comment "A straight-chain alkane with 12 carbon atoms. It has been isolated from the essential oils of various plants including Zingiber officinale (ginger)." ;
rdfs:subClassOf obo:CHEBI_18310 .
obo:GO_0006892 a rdfs:Class ;
rdfs:label "post-Golgi vesicle-mediated transport" ;
rdfs:comment "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles." ;
rdfs:subClassOf obo:GO_0048193 .
obo:GO_0098797 a rdfs:Class ;
rdfs:label "plasma membrane protein complex" ;
rdfs:comment "Any protein complex that is part of the plasma membrane." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0098796 .
obo:GO_1901955 a rdfs:Class ;
rdfs:label "negative regulation of retrograde dense core granule transport" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901609 , obo:GO_1901954 , obo:GO_1904810 , obo:GO_2001018 .
obo:CHEBI_582124 a rdfs:Class ;
rdfs:label "myriocin" ;
rdfs:comment "An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity." ;
rdfs:subClassOf obo:CHEBI_35785 , obo:CHEBI_35868 , obo:CHEBI_59755 .
obo:PHIPO_0000593 a rdfs:Class ;
rdfs:label "resistance to oxacillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to oxacillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:PHIPO_0000474 a rdfs:Class ;
rdfs:label "abnormal number of lipid droplets"@en ;
rdfs:comment "A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain a different number of lipid droplets than normal." ;
rdfs:subClassOf obo:PHIPO_0000478 .
obo:PHIPO_0000808 a rdfs:Class ;
rdfs:label "sensitive to pyrimethanil"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrimethanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0072678 a rdfs:Class ;
rdfs:label "T cell migration" ;
rdfs:comment "The movement of a T cell within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0072676 .
obo:PHIPO_0000149 a rdfs:Class ;
rdfs:label "decreased DNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000145 .
obo:GO_0032370 a rdfs:Class ;
rdfs:label "positive regulation of lipid transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032368 , obo:GO_0051050 , obo:GO_0065007 , obo:GO_1905954 .
obo:GO_0042180 a rdfs:Class ;
rdfs:label "ketone metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0051469 a rdfs:Class ;
rdfs:label "vesicle fusion with vacuole" ;
rdfs:comment "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole." ;
rdfs:subClassOf obo:GO_0006906 , obo:GO_0009987 , obo:GO_0097576 .
obo:CHEBI_38418 a rdfs:Class ;
rdfs:label "1,3-thiazoles" ;
rdfs:subClassOf obo:CHEBI_48901 .
obo:CL_0000586 a rdfs:Class ;
rdfs:label "germ cell" ;
rdfs:comment "The reproductive cell in multicellular organisms." ;
rdfs:subClassOf obo:CL_0000039 .
obo:GO_1905064 a rdfs:Class ;
rdfs:label "negative regulation of vascular associated smooth muscle cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051151 , obo:GO_0065007 , obo:GO_1905063 .
obo:CHEBI_83750 a rdfs:Class ;
rdfs:label "(2S,3S)-cyproconazole" ;
rdfs:comment "The (2S,3S)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol." ;
rdfs:subClassOf obo:CHEBI_83748 .
obo:GO_0021551 a rdfs:Class ;
rdfs:label "central nervous system morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0099565 a rdfs:Class ;
rdfs:label "chemical synaptic transmission, postsynaptic" ;
rdfs:comment "The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol." ;
rdfs:subClassOf obo:GO_0007166 , obo:GO_0050877 .
obo:GO_1902811 a rdfs:Class ;
rdfs:label "positive regulation of skeletal muscle fiber differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation." ;
rdfs:subClassOf obo:GO_0010831 , obo:GO_0065007 , obo:GO_1902809 , obo:GO_2001016 .
obo:GO_0014020 a rdfs:Class ;
rdfs:label "primary neural tube formation" ;
rdfs:comment "The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube." ;
rdfs:subClassOf obo:GO_0001838 .
a rdfs:Class ;
rdfs:label "SOX6" .
obo:UBERON_0001366 a rdfs:Class ;
rdfs:label "parietal peritoneum" ;
rdfs:comment "The outer layer of peritoneum that is attached to the abdominal and pelvic walls." ;
rdfs:subClassOf obo:UBERON_0022351 .
obo:UBERON_0010295 a rdfs:Class ;
rdfs:label "substantia propria of sclera" ;
rdfs:comment "A stroma that is part of a sclera." ;
rdfs:subClassOf obo:UBERON_0003891 , obo:UBERON_0010291 .
obo:CLM_1000075 a rdfs:Class ;
rdfs:label "NS forest marker set of Lamp5 Lhx6 neuron (Human neocortex)." ;
rdfs:subClassOf obo:SO_0001260 .
obo:GO_0000279 a rdfs:Class ;
rdfs:label "M phase" ;
rdfs:comment "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase." ;
rdfs:subClassOf obo:GO_0022403 .
obo:PHIPO_0000177 a rdfs:Class ;
rdfs:label "obsolete yeast-form growth phenotype" ;
rdfs:comment "A single species population phenotype in which affects the population growth during the yeast-form lifecycle stage." .
obo:GO_0071677 a rdfs:Class ;
rdfs:label "positive regulation of mononuclear cell migration" ;
rdfs:comment "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0002687 , obo:GO_0065007 , obo:GO_0071675 .
obo:PATO_0002478 a rdfs:Class ;
rdfs:label "transversely striated" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer." ;
rdfs:subClassOf obo:PATO_0001410 .
obo:GO_0021670 a rdfs:Class ;
rdfs:label "lateral ventricle development" ;
rdfs:comment "The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle." ;
rdfs:subClassOf obo:GO_0048856 .
obo:PHIPO_0000213 a rdfs:Class ;
rdfs:label "host chlorosis absent in presence of pathogen"@en ;
rdfs:comment "A pathogen-host interaction phenotype in which host chlorosis is absent." ;
rdfs:subClassOf obo:PHIPO_0000200 .
obo:GO_0044088 a rdfs:Class ;
rdfs:label "regulation of vacuole organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:UBERON_0019264 a rdfs:Class ;
rdfs:label "gray matter of forebrain" ;
rdfs:subClassOf obo:UBERON_0002020 , obo:UBERON_0003528 .
obo:UBERON_0003057 a rdfs:Class ;
rdfs:label "chordal neural plate" ;
rdfs:comment "The portion of neural plate posterior to the mid-hindbrain junction." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0000785 a rdfs:Class ;
rdfs:label "chromatin" ;
rdfs:comment "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_1902692 a rdfs:Class ;
rdfs:label "regulation of neuroblast proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuroblast proliferation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000177 .
obo:GO_0002732 a rdfs:Class ;
rdfs:label "positive regulation of dendritic cell cytokine production" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production." ;
rdfs:subClassOf obo:GO_0002705 , obo:GO_0002720 , obo:GO_0002730 , obo:GO_0065007 .
obo:GO_0061183 a rdfs:Class ;
rdfs:label "regulation of dermatome development" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0051939 a rdfs:Class ;
rdfs:label "gamma-aminobutyric acid import" ;
rdfs:comment "The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle." ;
rdfs:subClassOf obo:GO_0015800 , obo:GO_0015812 .
obo:GO_0010660 a rdfs:Class ;
rdfs:label "regulation of muscle cell apoptotic process" ;
rdfs:comment "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:GO_0021583 a rdfs:Class ;
rdfs:label "pons morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PHIPO_0001134 a rdfs:Class ;
rdfs:label "sensitive to potassium chloride"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to potassium chloride. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0001833 a rdfs:Class ;
rdfs:label "inner cell mass cell proliferation" ;
rdfs:comment "The proliferation of cells in the inner cell mass." ;
rdfs:subClassOf obo:GO_0008283 .
obo:PHIPO_0000256 a rdfs:Class ;
rdfs:label "transport phenotype"@en ;
rdfs:comment "A single organism cell phenotype that affects a transport process." ;
rdfs:subClassOf obo:PHIPO_0000235 .
obo:CHEBI_83733 a rdfs:Class ;
rdfs:label "(R)-vinclozolin" ;
rdfs:comment "A 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione that is the (R)-enantiomer of vinclozolin." ;
rdfs:subClassOf obo:CHEBI_83732 .
obo:CHEBI_6923 a rdfs:Class ;
rdfs:label "miconazole" ;
rdfs:comment "A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87069 , obo:CHEBI_87071 .
obo:UBERON_0010084 a rdfs:Class ;
rdfs:label "future diaphragm" ;
rdfs:comment "A structure that will develop into a diaphragm." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_0006584 a rdfs:Class ;
rdfs:label "catecholamine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ;
rdfs:subClassOf obo:GO_0006576 , obo:GO_0008152 , obo:GO_0009712 .
obo:UBERON_0002561 a rdfs:Class ;
rdfs:label "lumen of central nervous system" ;
rdfs:comment "The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube." ;
rdfs:subClassOf obo:UBERON_0002558 .
obo:GO_0001935 a rdfs:Class ;
rdfs:label "endothelial cell proliferation" ;
rdfs:comment "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0050673 .
obo:CHEBI_78693 a rdfs:Class ;
rdfs:label "(R)-bifonazole" ;
rdfs:comment "A 1-[biphenyl-4-yl(phenyl)methyl]imidazole that is the R-enantiomer of bifonazole." ;
rdfs:subClassOf obo:CHEBI_78692 .
obo:UBERON_0013150 a rdfs:Class ;
rdfs:label "future brain vesicle" ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:UBERON_0007414 a rdfs:Class ;
rdfs:label "nucleus of midbrain tegmentum" ;
rdfs:comment "A nucleus of brain that spans a midbrain tegmentum." ;
rdfs:subClassOf obo:UBERON_0000125 .
obo:NCBITaxon_33208 a rdfs:Class ;
rdfs:label "Metazoa" ;
rdfs:subClassOf obo:NCBITaxon_33154 .
obo:GO_0032291 a rdfs:Class ;
rdfs:label "axon ensheathment in central nervous system" ;
rdfs:comment "The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." ;
rdfs:subClassOf obo:GO_0008366 .
obo:UBERON_0003457 a rdfs:Class ;
rdfs:label "head bone" ;
rdfs:comment "A bone that is part of a head [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0007914 .
obo:GO_0001774 a rdfs:Class ;
rdfs:label "microglial cell activation" ;
rdfs:comment "The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0002269 , obo:GO_0042116 , obo:GO_0061900 .
obo:GO_0048753 a rdfs:Class ;
rdfs:label "pigment granule organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0016050 .
obo:GO_0003248 a rdfs:Class ;
rdfs:label "heart capillary growth" ;
rdfs:comment "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle." ;
rdfs:subClassOf obo:GO_0048589 .
obo:GO_0051146 a rdfs:Class ;
rdfs:label "striated muscle cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0042692 .
obo:GO_0061882 a rdfs:Class ;
rdfs:label "negative regulation of anterograde axonal transport of mitochondrion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0061880 , obo:GO_0065007 .
obo:PHIPO_0000545 a rdfs:Class ;
rdfs:label "resistance to chlorothalonil"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to chlorothalonil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_0000151 a rdfs:Class ;
rdfs:label "secretory cell" ;
rdfs:comment "A cell that specializes in controlled release of one or more substances." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0099072 a rdfs:Class ;
rdfs:label "regulation of postsynaptic membrane neurotransmitter receptor levels" ;
rdfs:comment "Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane." ;
rdfs:subClassOf obo:GO_0065008 .
obo:GO_1904988 a rdfs:Class ;
rdfs:label "negative regulation of endothelial cell activation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation." ;
rdfs:subClassOf obo:GO_0050866 , obo:GO_0065007 , obo:GO_1904987 .
obo:UBERON_8480001 a rdfs:Class ;
rdfs:label "capillary of brain" ;
rdfs:comment "A capillary that is part of the brain." ;
rdfs:subClassOf obo:UBERON_0001982 , obo:UBERON_0003499 .
obo:CHEBI_23018 a rdfs:Class ;
rdfs:label "EC 4.2.1.1 (carbonic anhydrase) inhibitor" ;
rdfs:comment "An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H+ ions by the proximal kidney tubule." ;
rdfs:subClassOf obo:CHEBI_76907 .
obo:CL_0000014 a rdfs:Class ;
rdfs:label "germ line stem cell" ;
rdfs:comment "A stem cell that is the precursor of gametes." ;
rdfs:subClassOf obo:CL_0000034 , obo:CL_0000039 .
obo:GO_1901343 a rdfs:Class ;
rdfs:label "negative regulation of vasculature development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1901342 .
obo:GO_0035562 a rdfs:Class ;
rdfs:label "negative regulation of chromatin binding" ;
rdfs:comment "Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." ;
rdfs:subClassOf obo:GO_0051100 , obo:GO_0065007 .
obo:UBERON_0010743 a rdfs:Class ;
rdfs:label "meningeal cluster" ;
rdfs:comment "The collection of all meningeal layers that line a central nervous system." ;
rdfs:subClassOf obo:UBERON_0034925 .
obo:RO_0002351 a rdf:Property ;
rdfs:label "has member"@en ;
rdfs:comment "has member is a mereological relation between a collection and an item." ;
rdfs:range ;
rdfs:subPropertyOf obo:BFO_0000051 .
obo:UBERON_0003338 a rdfs:Class ;
rdfs:label "ganglion of peripheral nervous system" ;
rdfs:comment "A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections. (CUMBO)." ;
rdfs:subClassOf obo:UBERON_0000045 .
obo:UBERON_0001585 a rdfs:Class ;
rdfs:label "anterior vena cava" ;
rdfs:comment "A vein that carries deoxygenated blood from the upper half of the body into the right atrium of the heart." ;
rdfs:subClassOf obo:UBERON_0004087 .
obo:GO_1905126 a rdfs:Class ;
rdfs:label "regulation of axo-dendritic protein transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of axo-dendritic protein transport." ;
rdfs:subClassOf obo:GO_0033157 , obo:GO_0060632 , obo:GO_0065007 .
obo:CL_4307109 a rdfs:Class ;
rdfs:label "OEC NN_1 Adamts12 olfactory ensheathing cell (Mmus)" ;
rdfs:comment "A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn5 (Mmus), Adamts12 (Mmus). It is distinguished from other OEC cells by expression of Adamts12. These cells are located in the brain , in or close to the regions: olfactory nerve layer of main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5289 OEC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301615 .
obo:CL_0001028 a rdfs:Class ;
rdfs:label "CD7-positive lymphoid progenitor cell" ;
rdfs:comment "CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative." ;
rdfs:subClassOf obo:CL_0000051 .
obo:CL_0002547 a rdfs:Class ;
rdfs:label "fibroblast of the aortic adventitia" ;
rdfs:comment "A fibroblast of the aortic adventitia." ;
rdfs:subClassOf obo:CL_1000306 .
obo:GO_0002038 a rdfs:Class ;
rdfs:label "positive regulation of L-glutamate import across plasma membrane" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell." ;
rdfs:subClassOf obo:GO_0002036 , obo:GO_0032892 , obo:GO_0034764 , obo:GO_0051957 , obo:GO_0065007 .
obo:UBERON_0001725 a rdfs:Class ;
rdfs:label "cranial synchondrosis" ;
rdfs:comment "The cartilaginous joints of the skull; these include sphenoethmoidal synchondrosis, sphenooccipital synchondrosis, sphenopetrosal synchondrosis, petrooccipital synchondrosis, anterior intraoccipital synchondrosis and posterior intraoccipital synchondrosis." ;
rdfs:subClassOf obo:UBERON_0002215 .
obo:GO_0086070 a rdfs:Class ;
rdfs:label "SA node cell to atrial cardiac muscle cell communication" ;
rdfs:comment "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0086065 .
obo:CHEBI_77748 a rdfs:Class ;
rdfs:label "EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor" ;
rdfs:comment "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44)." ;
rdfs:subClassOf obo:CHEBI_76895 .
obo:PHIPO_0000699 a rdfs:Class ;
rdfs:label "resistance to doripenem"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to doripenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000693 .
obo:CHEBI_7508 a rdfs:Class ;
rdfs:label "framycetin" ;
rdfs:comment "A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B." ;
rdfs:subClassOf obo:CHEBI_47779 , obo:CHEBI_61800 .
obo:CHEBI_87134 a rdfs:Class ;
rdfs:label "morpholine fungicide" ;
rdfs:comment "Any morpholine antifungal agent used as a fungicide." ;
rdfs:subClassOf obo:CHEBI_87132 .
obo:PHIPO_0000956 a rdfs:Class ;
rdfs:label "normal asexual spore germination frequency"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of asexual spore germination is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000509 .
obo:UBERON_0002346 a rdfs:Class ;
rdfs:label "neurectoderm" ;
rdfs:comment "Embryonic ectoderm that gives rise to nervous tissue." ;
rdfs:subClassOf obo:UBERON_0000923 , obo:UBERON_0004121 .
obo:GO_2000785 a rdfs:Class ;
rdfs:label "regulation of autophagosome assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of autophagosome assembly." ;
rdfs:subClassOf obo:GO_0044088 , obo:GO_0065007 , obo:GO_1902115 .
obo:CHEBI_65296 a rdfs:Class ;
rdfs:label "primary ammonium ion" ;
rdfs:comment "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:CHEBI_27701 a rdfs:Class ;
rdfs:label "oxytetracycline" ;
rdfs:comment "A tetracycline used for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae." ;
rdfs:subClassOf obo:CHEBI_26895 .
obo:CL_4307098 a rdfs:Class ;
rdfs:label "NFOL NN_2 9630013A20Rik newly formed oligodendrocyte (Mmus)" ;
rdfs:comment "A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Grin2b (Mmus). It is distinguished from other NFOL NN_2 cells by expression of 9630013A20Rik, Grin2b. These cells are located in the Midbrain, Thalamus, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5278 NFOL NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301612 .
obo:PHIPO_0001102 a rdfs:Class ;
rdfs:label "presence of pathogen asexual sporulation structures within host lesion"@en ;
rdfs:comment "A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual sporulation structures within a host lesion is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000472 .
obo:GO_0045655 a rdfs:Class ;
rdfs:label "regulation of monocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of monocyte differentiation." ;
rdfs:subClassOf obo:GO_0002761 , obo:GO_0065007 .
obo:UBERON_0003304 a rdfs:Class ;
rdfs:label "mesoderm blood island" ;
rdfs:comment "A blood island that is part of a mesoderm." ;
rdfs:subClassOf obo:UBERON_0003061 , obo:UBERON_0005291 , obo:UBERON_0007503 , obo:UBERON_0012275 .
obo:GO_0010700 a rdfs:Class ;
rdfs:label "negative regulation of norepinephrine secretion" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine." ;
rdfs:subClassOf obo:GO_0014061 , obo:GO_0033604 , obo:GO_0065007 .
obo:PR_P22091 a rdfs:Class ;
rdfs:label "T-cell acute lymphocytic leukemia protein 1 homolog (mouse)" ;
rdfs:comment "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000016043 , obo:PR_000029032 .
obo:GO_0048580 a rdfs:Class ;
rdfs:label "regulation of post-embryonic development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000026 .
obo:GO_0060437 a rdfs:Class ;
rdfs:label "lung growth" ;
rdfs:comment "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." ;
rdfs:subClassOf obo:GO_0035265 , obo:GO_0048589 .
obo:PHIPO_0000284 a rdfs:Class ;
rdfs:label "pigment phenotype"@en ;
rdfs:comment "A single species individual organism phenotype affecting the deposition or aggregation of coloring matter in a cell." ;
rdfs:subClassOf obo:PHIPO_0000402 .
obo:CHEBI_100147 a rdfs:Class ;
rdfs:label "nalidixic acid" ;
rdfs:comment "A monocarboxylic acid comprising 1,8-naphthyridin-4-one substituted by carboxylic acid, ethyl and methyl groups at positions 3, 1, and 7, respectively. An orally administered antibacterial, it is used in the treatment of lower urinary-tract infections due to Gram-negative bacteria, including the majority of E. coli, Enterobacter, Klebsiella, and Proteus species." ;
rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_73537 , obo:CHEBI_86324 .
obo:UBERON_0006250 a rdfs:Class ;
rdfs:label "infundibular recess of 3rd ventricle" ;
rdfs:comment "A funnel-shaped diverticulum that extends downward from the anterior aspect of the floor of the third ventricle into the infundibulum of the hypophysis; the embryonic structure gives rise the neural component of the pituitary (pas nervosa)." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005291 , obo:UBERON_0007499 .
obo:CHEBI_63299 a rdfs:Class ;
rdfs:label "carbohydrate derivative" ;
rdfs:comment "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." ;
rdfs:subClassOf obo:CHEBI_78616 .
obo:GO_0007350 a rdfs:Class ;
rdfs:label "blastoderm segmentation" ;
rdfs:comment "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo." ;
rdfs:subClassOf obo:GO_0009880 , obo:GO_0035282 .
obo:GO_0061075 a rdfs:Class ;
rdfs:label "positive regulation of neural retina development" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." ;
rdfs:subClassOf obo:GO_0061074 , obo:GO_0065007 , obo:GO_1902868 .
obo:UBERON_0007242 a rdfs:Class ;
rdfs:label "tunica intima of vein" ;
rdfs:comment "A tunica intima that is part of a vein." ;
rdfs:subClassOf obo:UBERON_0002523 , obo:UBERON_0004797 .
obo:UBERON_0001444 a rdfs:Class ;
rdfs:label "subdivision of head" ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:CHEBI_35190 a rdfs:Class ;
rdfs:label "diterpene" ;
rdfs:comment "A C20 terpene." ;
rdfs:subClassOf obo:CHEBI_35186 .
obo:GO_1905310 a rdfs:Class ;
rdfs:label "regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:CHEBI_39216 a rdfs:Class ;
rdfs:label "antibiotic acaricide" ;
rdfs:subClassOf obo:CHEBI_22153 , obo:CHEBI_39215 .
obo:GO_1904819 a rdfs:Class ;
rdfs:label "parietal peritoneum development" ;
rdfs:comment "The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_35679 a rdfs:Class ;
rdfs:label "antilipemic drug" ;
rdfs:comment "A substance used to treat hyperlipidemia (an excess of lipids in the blood)." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:UBERON_0005357 a rdfs:Class ;
rdfs:label "brain ependyma" ;
rdfs:comment "The ependymal cell layer that lines the brain ventricles." ;
rdfs:subClassOf obo:UBERON_0004670 .
obo:UBERON_0010075 a rdfs:Class ;
rdfs:label "sacral neural crest" ;
rdfs:comment "One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. The vagal and sacral neural crest cells develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia." ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:GO_0060408 a rdfs:Class ;
rdfs:label "regulation of acetylcholine metabolic process" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ;
rdfs:subClassOf obo:GO_0033238 , obo:GO_0065007 , obo:GO_0080090 .
obo:GO_0042424 a rdfs:Class ;
rdfs:label "catecholamine catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ;
rdfs:subClassOf obo:GO_0006584 , obo:GO_0009056 , obo:GO_0019614 , obo:GO_0042402 .
obo:GO_0098636 a rdfs:Class ;
rdfs:label "protein complex involved in cell adhesion" ;
rdfs:comment "Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell." ;
rdfs:subClassOf obo:GO_0032991 .
obo:GO_1903353 a rdfs:Class ;
rdfs:label "regulation of nucleus organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of nucleus organization." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:CHEBI_22712 a rdfs:Class ;
rdfs:label "benzenes" ;
rdfs:comment "Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_33836 .
obo:UBERON_0002513 a rdfs:Class ;
rdfs:label "endochondral bone" ;
rdfs:comment "Replacement bone that forms within cartilage." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0010363 .
obo:RO_0002285 a rdf:Property ;
rdfs:label "developmentally replaces"@en ;
rdfs:comment "x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else" ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002258 .
obo:GO_1900142 a rdfs:Class ;
rdfs:label "negative regulation of oligodendrocyte apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process." ;
rdfs:subClassOf obo:GO_0034351 , obo:GO_0065007 , obo:GO_1900141 .
obo:GO_0042692 a rdfs:Class ;
rdfs:label "muscle cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0002577 a rdfs:Class ;
rdfs:label "regulation of antigen processing and presentation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0065007 .
obo:GO_0044706 a rdfs:Class ;
rdfs:label "multi-multicellular organism process" ;
rdfs:comment "A multicellular organism process which involves another multicellular organism of the same or different species." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0030705 a rdfs:Class ;
rdfs:label "cytoskeleton-dependent intracellular transport" ;
rdfs:comment "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." ;
rdfs:subClassOf obo:GO_0046907 .
obo:GO_0051657 a rdfs:Class ;
rdfs:label "maintenance of organelle location" ;
rdfs:comment "Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0051651 .
obo:CL_0000118 a rdfs:Class ;
rdfs:label "basket cell" ;
rdfs:comment "Basket cells are inhibitory GABAergic interneurons of the brain. In general, dendrites of basket cells are free branching and contain smooth spines. Axons are highly branched. The branched axonal arborizations give rise to basket-like structures that surround the soma of the target cell. Basket cells form axo-somatic synapses, meaning their synapses target somas of other cells." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_0011005 .
obo:UBERON_0010363 a rdfs:Class ;
rdfs:label "endochondral element" ;
rdfs:comment "A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification." ;
rdfs:subClassOf obo:UBERON_0004765 .
obo:GO_0050778 a rdfs:Class ;
rdfs:label "positive regulation of immune response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ;
rdfs:subClassOf obo:GO_0002684 , obo:GO_0048584 , obo:GO_0050776 , obo:GO_0065007 .
obo:PHIPO_0001332 a rdfs:Class ;
rdfs:label "resistance to procymidone"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to procymidone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_59779 a rdfs:Class ;
rdfs:label "cyclic ketal" ;
rdfs:comment "A ketal in the molecule of which the ketal carbon and one or both oxygen atoms thereon are members of a ring." ;
rdfs:subClassOf obo:CHEBI_38104 , obo:CHEBI_59777 .
obo:GO_1901338 a rdfs:Class ;
rdfs:label "catecholamine binding" ;
rdfs:comment "Binding to catecholamine." ;
rdfs:subClassOf obo:GO_0005488 .
obo:GO_0140152 a rdfs:Class ;
rdfs:label "collagenous component of interstitial matrix" ;
rdfs:comment "Main components of the interstitial matrix solid phase, including fibrillar and fibril-associated collagens." ;
rdfs:subClassOf obo:GO_0030312 .
obo:CHEBI_26155 a rdfs:Class ;
rdfs:label "plant growth regulator" ;
rdfs:comment "A chemical, natural or artificial, that can affect the rate of growth of a plant." ;
rdfs:subClassOf obo:CHEBI_39317 .
obo:PHIPO_0001355 a rdfs:Class ;
rdfs:label "normal growth on prothioconazole" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to prothioconazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0012501 a rdfs:Class ;
rdfs:label "programmed cell death" ;
rdfs:comment "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." ;
rdfs:subClassOf obo:GO_0008219 .
obo:GO_0003333 a rdfs:Class ;
rdfs:label "amino acid transmembrane transport" ;
rdfs:comment "The process in which an amino acid is transported across a membrane." ;
rdfs:subClassOf obo:GO_0006865 , obo:GO_0055085 .
obo:PR_P53566 a rdfs:Class ;
rdfs:label "CCAAT/enhancer-binding protein alpha (mouse)" ;
rdfs:comment "A CCAAT/enhancer-binding protein alpha that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000005307 , obo:PR_000029032 .
obo:GO_0048762 a rdfs:Class ;
rdfs:label "mesenchymal cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." ;
rdfs:subClassOf obo:GO_0030154 .
obo:UBERON_0010527 a rdfs:Class ;
rdfs:label "cavity of bone organ" ;
rdfs:comment "An organ cavity that surrounded_by a bone." ;
rdfs:subClassOf obo:UBERON_0002558 .
obo:CHEBI_16716 a rdfs:Class ;
rdfs:label "benzene" ;
rdfs:comment "A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised π system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system." ;
rdfs:subClassOf obo:CHEBI_134179 , obo:CHEBI_22712 , obo:CHEBI_33842 .
obo:UBERON_0005491 a rdfs:Class ;
rdfs:label "glossopharyngeal neural crest" ;
rdfs:comment "Cranial neural crest which gives rise to the glossopharyngeal ganglion." ;
rdfs:subClassOf obo:UBERON_0003099 .
obo:UBERON_0005911 a rdfs:Class ;
rdfs:label "endo-epithelium" ;
rdfs:comment "Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004119 .
obo:CL_1000413 a rdfs:Class ;
rdfs:label "endothelial cell of artery" ;
rdfs:comment "A blood vessel endothelial cell that is part of an arterial endothelium." ;
rdfs:subClassOf obo:CL_0000071 , obo:CL_0000115 .
obo:CHEBI_6032 a rdfs:Class ;
rdfs:label "isonicotinic acid" ;
rdfs:comment "A pyridinemonocarboxylic acid in which the carboxy group is at position 4 of the pyridine ring." ;
rdfs:subClassOf obo:CHEBI_26420 .
obo:UBERON_0002401 a rdfs:Class ;
rdfs:label "visceral pleura" ;
rdfs:comment "The inner serous membrane of the pulmonary pleural. The visceral pleura lines the lungs." ;
rdfs:subClassOf obo:UBERON_0004923 , obo:UBERON_0022350 .
obo:UBERON_0011824 a rdfs:Class ;
rdfs:label "fibrous connective tissue" ;
rdfs:subClassOf obo:UBERON_0011822 .
obo:CL_2000025 a rdfs:Class ;
rdfs:label "spinal cord oligodendrocyte" ;
rdfs:comment "Any oligodendrocyte that is part of a spinal cord." ;
rdfs:subClassOf obo:CL_0000128 .
obo:CHEBI_53661 a rdfs:Class ;
rdfs:label "alexidine" ;
rdfs:comment "An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge." ;
rdfs:subClassOf obo:CHEBI_53662 , obo:CHEBI_60911 .
obo:CHEBI_29347 a rdfs:Class ;
rdfs:label "monocarboxylic acid amide" ;
rdfs:comment "A carboxamide derived from a monocarboxylic acid." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:GO_0006576 a rdfs:Class ;
rdfs:label "biogenic amine metabolic process" ;
rdfs:comment "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ;
rdfs:subClassOf obo:GO_0009308 .
obo:GO_0016877 a rdfs:Class ;
rdfs:label "ligase activity, forming carbon-sulfur bonds" ;
rdfs:comment "Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." ;
rdfs:subClassOf obo:GO_0016874 .
obo:GO_0060426 a rdfs:Class ;
rdfs:label "lung vasculature development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs." ;
rdfs:subClassOf obo:GO_0001944 , obo:GO_0048856 .
obo:GO_0170041 a rdfs:Class ;
rdfs:label "non-proteinogenic amino acid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving non-proteingenic amino acids." ;
rdfs:subClassOf obo:GO_0006520 , obo:GO_0008152 , obo:GO_0019752 .
obo:GO_1901952 a rdfs:Class ;
rdfs:label "negative regulation of anterograde dense core granule transport" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901609 , obo:GO_1901951 , obo:GO_1904810 .
obo:PR_P17679 a rdfs:Class ;
rdfs:label "erythroid transcription factor (mouse)" ;
rdfs:comment "An erythroid transcription factor that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000007857 , obo:PR_000029032 .
obo:UBERON_0011766 a rdfs:Class ;
rdfs:label "left recurrent laryngeal nerve" ;
rdfs:subClassOf obo:UBERON_0003716 , obo:UBERON_0015212 .
obo:GO_0060916 a rdfs:Class ;
rdfs:label "mesenchymal cell proliferation involved in lung development" ;
rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ;
rdfs:subClassOf obo:GO_0010463 .
obo:CHEBI_84055 a rdfs:Class ;
rdfs:label "pentose phosphate" ;
rdfs:comment "Any phospho sugar that is the phosphate derivative of pentose." ;
rdfs:subClassOf obo:CHEBI_33447 , obo:CHEBI_63409 .
obo:GO_1904106 a rdfs:Class ;
rdfs:label "protein localization to microvillus" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a microvillus." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_1903119 .
obo:GO_0000280 a rdfs:Class ;
rdfs:label "nuclear division" ;
rdfs:comment "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." ;
rdfs:subClassOf obo:GO_0048285 .
obo:CHEBI_33636 a rdfs:Class ;
rdfs:label "bicyclic compound" ;
rdfs:comment "A molecule that features two fused rings." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:PHIPO_0000964 a rdfs:Class ;
rdfs:label "loss of virulence"@en ;
rdfs:comment "A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is abolished on a specific host genotype." ;
rdfs:subClassOf obo:PHIPO_0000015 .
obo:GO_1904829 a rdfs:Class ;
rdfs:label "regulation of aortic smooth muscle cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905063 .
obo:PHIPO_0000846 a rdfs:Class ;
rdfs:label "sensitive to chlorothalonil"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to chlorothalonil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_32864 a rdfs:Class ;
rdfs:label "L-prolinium" ;
rdfs:comment "An optically active form of prolinium having L-configuration." ;
rdfs:subClassOf obo:CHEBI_32872 .
obo:GO_0048934 a rdfs:Class ;
rdfs:label "peripheral nervous system neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030182 .
obo:CHEBI_33408 a rdfs:Class ;
rdfs:label "pnictogen oxoacid" ;
rdfs:subClassOf obo:CHEBI_24833 , obo:CHEBI_33302 .
obo:CL_0001060 a rdfs:Class ;
rdfs:label "hematopoietic oligopotent progenitor cell, lineage-negative" ;
rdfs:comment "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers." ;
rdfs:subClassOf obo:CL_0002032 .
obo:UBERON_0002417 a rdfs:Class ;
rdfs:label "abdominal segment of trunk" ;
rdfs:comment "The abdominal segment of the torso." ;
rdfs:subClassOf obo:UBERON_0009569 , obo:UBERON_0011676 .
obo:PHIPO_0000806 a rdfs:Class ;
rdfs:label "sensitive to trovafloxacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to trovafloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0048645 a rdfs:Class ;
rdfs:label "animal organ formation" ;
rdfs:comment "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0035719 a rdfs:Class ;
rdfs:label "tRNA import into nucleus" ;
rdfs:comment "The directed movement of tRNA from the cytoplasm to the nucleus." ;
rdfs:subClassOf obo:GO_0006404 , obo:GO_0006810 , obo:GO_0051031 .
obo:CHEBI_28306 a rdfs:Class ;
rdfs:label "semicarbazide" ;
rdfs:comment "A monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine." ;
rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_35363 , obo:CHEBI_47857 , obo:CHEBI_64708 .
obo:PHIPO_0000986 a rdfs:Class ;
rdfs:label "increased extent of pathogen-associated host lesions"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion occurs to a greater extent than normal." ;
rdfs:subClassOf obo:PHIPO_0000480 .
obo:PHIPO_0001022 a rdfs:Class ;
rdfs:label "altered cellular cAMP level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of cyclic AMP measured in a cell differs from normal." ;
rdfs:subClassOf obo:PHIPO_0000944 .
obo:GO_0045931 a rdfs:Class ;
rdfs:label "positive regulation of mitotic cell cycle" ;
rdfs:comment "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0045787 , obo:GO_0065007 .
obo:CHEBI_36027 a rdfs:Class ;
rdfs:label "stilbenol" ;
rdfs:comment "Any stilbenoid with at least one phenolic group." ;
rdfs:subClassOf obo:CHEBI_26776 , obo:CHEBI_33853 .
obo:UBERON_0003315 a rdfs:Class ;
rdfs:label "mesenchyme of ovary" ;
rdfs:comment "Mesenchyme that is part of a developing ovary [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0003855 .
obo:CHEBI_83628 a rdfs:Class ;
rdfs:label "N-acylammonia" ;
rdfs:comment "A carboxamide obtained by the formal condensation of the carboxy group of any carboxylic acid with ammonia." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:UBERON_0001882 a rdfs:Class ;
rdfs:label "nucleus accumbens" ;
rdfs:comment "A region of the brain consisting of a collection of neurons located in the forebrain ventral to the caudate and putamen. (caudoputamen in rodent) and continuous with these structures. There is no distinct boundary between the nucleus accumbens and the caudate/putamen, but in rodents, it can be identified by its lack of traversing fiber bundles in comparison to the dorsal striatum. Its principle neuron is the medium spiny neuron. Together with the neostriatum (caudate nucleus and putamen), the nucleus accumbens forms the striatum." ;
rdfs:subClassOf obo:UBERON_0009663 .
obo:GO_0009056 a rdfs:Class ;
rdfs:label "catabolic process" ;
rdfs:comment "A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0046851 a rdfs:Class ;
rdfs:label "negative regulation of bone remodeling" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling." ;
rdfs:subClassOf obo:GO_0034104 , obo:GO_0046850 , obo:GO_0065007 .
obo:PATO_0001992 a rdfs:Class ;
rdfs:label "cellularity" ;
rdfs:comment "An organismal quality inhering in a bearer by virtue of the bearer's consisting cells." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:PHIPO_0000371 a rdfs:Class ;
rdfs:label "decreased number of pathogen penetration structure when near host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the frequency of occurrence of pathogen penetration stuctures near the host are decreased." ;
rdfs:subClassOf obo:PHIPO_0000369 .
obo:GO_0015813 a rdfs:Class ;
rdfs:label "L-glutamate transmembrane transport" ;
rdfs:comment "The directed movement of L-glutamate across a membrane by means of some agent such as a transporter or a pore." ;
rdfs:subClassOf obo:GO_0015800 , obo:GO_0051938 , obo:GO_1902475 .
obo:GO_1904650 a rdfs:Class ;
rdfs:label "negative regulation of fat cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0065007 , obo:GO_1904649 .
obo:GO_0006417 a rdfs:Class ;
rdfs:label "regulation of translation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ;
rdfs:subClassOf obo:GO_0010608 , obo:GO_0051246 , obo:GO_0065007 .
obo:UBERON_0000033 a rdfs:Class ;
rdfs:label "head" ;
rdfs:comment "The head is the anterior-most division of the body [GO]." ;
rdfs:subClassOf obo:UBERON_0011676 .
obo:CHEBI_27656 a rdfs:Class ;
rdfs:label "camptothecin" ;
rdfs:comment "A pyranoindolizinoquinoline that is pyrano[3',4':6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer)." ;
rdfs:subClassOf obo:CHEBI_18946 , obo:CHEBI_26509 , obo:CHEBI_26878 , obo:CHEBI_48626 .
obo:GO_0031256 a rdfs:Class ;
rdfs:label "leading edge membrane" ;
rdfs:comment "The portion of the plasma membrane surrounding the leading edge of a motile cell." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0008217 a rdfs:Class ;
rdfs:label "regulation of blood pressure" ;
rdfs:comment "Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure." ;
rdfs:subClassOf obo:GO_0065008 .
obo:CL_1000493 a rdfs:Class ;
rdfs:label "mesothelial cell of visceral pleura" ;
rdfs:comment "A mesothelial cell that is part of the visceral pleura." ;
rdfs:subClassOf obo:CL_0000077 , obo:CL_1000491 .
obo:UBERON_0002128 a rdfs:Class ;
rdfs:label "superior olivary complex" ;
rdfs:comment "A collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system." ;
rdfs:subClassOf obo:UBERON_0007245 , obo:UBERON_0019263 .
obo:PHIPO_0000660 a rdfs:Class ;
rdfs:label "resistance to ceftazidime"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ceftazidime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001366 a rdfs:Class ;
rdfs:label "sensitive to bixafen" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to bixafen. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0021894 a rdfs:Class ;
rdfs:label "cerebral cortex GABAergic interneuron development" ;
rdfs:comment "The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0021884 , obo:GO_0032502 .
obo:GO_1904747 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic process involved in development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0051094 , obo:GO_0065007 , obo:GO_1904748 .
obo:GO_2000238 a rdfs:Class ;
rdfs:label "regulation of tRNA export from nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of tRNA export from nucleus." ;
rdfs:subClassOf obo:GO_0046831 , obo:GO_0065007 , obo:GO_2000197 .
obo:GO_0014860 a rdfs:Class ;
rdfs:label "neurotransmitter secretion involved in regulation of skeletal muscle contraction" ;
rdfs:comment "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." ;
rdfs:subClassOf obo:GO_0007269 .
obo:PHIPO_0000066 a rdfs:Class ;
rdfs:label "obsolete abnormal timing of asexual spore production" .
obo:GO_0000001 a rdfs:Class ;
rdfs:label "mitochondrion inheritance" ;
rdfs:comment "The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton." ;
rdfs:subClassOf obo:GO_0048308 , obo:GO_0048311 .
obo:GOREL_0002003 a rdf:Property ;
rdfs:label "results in distribution of" ;
rdfs:range .
obo:GO_1904888 a rdfs:Class ;
rdfs:label "cranial skeletal system development" ;
rdfs:comment "The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0033157 a rdfs:Class ;
rdfs:label "regulation of intracellular protein transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0051223 , obo:GO_0065007 .
obo:PHIPO_0000249 a rdfs:Class ;
rdfs:label "RNA localization phenotype"@en ;
rdfs:comment "A single organism phenotype that affects the localization of an RNA in a cell." ;
rdfs:subClassOf obo:PHIPO_0000235 .
obo:GO_0009719 a rdfs:Class ;
rdfs:label "response to endogenous stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." ;
rdfs:subClassOf obo:GO_0050896 .
obo:PATO_0000052 a rdfs:Class ;
rdfs:label "shape" ;
rdfs:comment "A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc)." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:GO_0006536 a rdfs:Class ;
rdfs:label "glutamate metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid." ;
rdfs:subClassOf obo:GO_0006520 , obo:GO_0008152 , obo:GO_0043648 .
obo:PR_000002064 a rdfs:Class ;
rdfs:label "macrosialin" ;
rdfs:comment "A lysosome-associated membrane protein that is a translation product of the human CD68 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001883 .
obo:PHIPO_0001360 a rdfs:Class ;
rdfs:label "sensitive to kresoxim-methyl" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to kresoxim-methyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000812 a rdfs:Class ;
rdfs:label "sensitive to norfloxacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to norfloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000868 a rdfs:Class ;
rdfs:label "sensitive to chlortetracycline"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to chlortetracycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0070661 a rdfs:Class ;
rdfs:label "leukocyte proliferation" ;
rdfs:comment "The expansion of a leukocyte population by cell division." ;
rdfs:subClassOf obo:GO_0008283 .
obo:CHEBI_51721 a rdfs:Class ;
rdfs:label "alpha,beta-unsaturated ketone" ;
rdfs:comment "A ketone of general formula R1R2C=CR3‒C(=O)R4 (R4 ≠ H) or R1C≡C‒C(=O)R2 (R2 ≠ H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:CHEBI_84292 a rdfs:Class ;
rdfs:label "dithiocarbamate anions" ;
rdfs:comment "Any organic sulfur anion resulting from the removal of a proton from any N-substituted dithiocarbamic acid." ;
rdfs:subClassOf obo:CHEBI_84291 .
obo:GO_1905900 a rdfs:Class ;
rdfs:label "negative regulation of smooth muscle tissue development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901862 , obo:GO_1905899 .
obo:GO_2000549 a rdfs:Class ;
rdfs:label "positive regulation of dendritic cell dendrite assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120034 , obo:GO_2000547 .
obo:GO_0150119 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to cell-cell junction" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0150106 , obo:GO_1903828 .
obo:UBERON_0000042 a rdfs:Class ;
rdfs:label "serous membrane" ;
rdfs:comment "Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0004120 .
obo:PHIPO_0000118 a rdfs:Class ;
rdfs:label "decreased pathogen growth after penetration of the barrier"@en ;
rdfs:comment "A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay is decreased." ;
rdfs:subClassOf obo:PHIPO_0000031 .
obo:PHIPO_0000292 a rdfs:Class ;
rdfs:label "decreased filament length"@en ;
rdfs:comment "A single species cell morphology phenotype where hyphal filaments are short in length." ;
rdfs:subClassOf obo:PHIPO_0001205 .
obo:GO_0031514 a rdfs:Class ;
rdfs:label "motile cilium" ;
rdfs:comment "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell." ;
rdfs:subClassOf obo:GO_0005929 .
obo:PHIPO_0000511 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction cell population phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that is observed at the level of a population of cells." .
obo:GO_0008053 a rdfs:Class ;
rdfs:label "mitochondrial fusion" ;
rdfs:comment "Merging of two or more mitochondria within a cell to form a single compartment." ;
rdfs:subClassOf obo:GO_0007005 , obo:GO_0009987 , obo:GO_0048284 .
obo:UBERON_0011138 a rdfs:Class ;
rdfs:label "postcranial axial skeletal system" ;
rdfs:comment "Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints." ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:GO_0048483 a rdfs:Class ;
rdfs:label "autonomic nervous system development" ;
rdfs:comment "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:GO_0140246 a rdfs:Class ;
rdfs:label "protein catabolic process at synapse" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a protein at a synapse." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0030163 .
obo:PHIPO_0001053 a rdfs:Class ;
rdfs:label "hyper-rugose unicellular colony shape"@en ;
rdfs:comment "A single species phenotype where the shape of a colony of unicellular individuals is more rugose (wrinkled; corrugated) than normal." ;
rdfs:subClassOf obo:PHIPO_0001051 .
obo:GO_0071867 a rdfs:Class ;
rdfs:label "response to monoamine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_1901698 .
obo:GO_1905083 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial translational elongation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation." ;
rdfs:subClassOf obo:GO_0045900 , obo:GO_0065007 , obo:GO_0070130 , obo:GO_1905082 .
obo:GO_0010629 a rdfs:Class ;
rdfs:label "negative regulation of gene expression" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0010558 , obo:GO_0065007 .
obo:GO_0062247 a rdfs:Class ;
rdfs:label "chloroplast vesicle" ;
rdfs:comment "A intracellular vesicle that is part of a chloroplast." ;
rdfs:subClassOf obo:GO_0031410 , obo:GO_0097708 .
obo:GO_0051588 a rdfs:Class ;
rdfs:label "regulation of neurotransmitter transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:GO_0002606 a rdfs:Class ;
rdfs:label "positive regulation of dendritic cell antigen processing and presentation" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002579 , obo:GO_0002604 , obo:GO_0065007 .
obo:PHIPO_0001005 a rdfs:Class ;
rdfs:label "normal host morphology during pathogen invasion"@en ;
rdfs:comment "A pathogen host interaction phenotype where the morphology of the host during pathogen invasion is normal (indistinguishable from wild type). This relates to the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0001002 .
obo:GO_0060041 a rdfs:Class ;
rdfs:label "retina development in camera-type eye" ;
rdfs:comment "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_52497 a rdfs:Class ;
rdfs:label "maneb" ;
rdfs:comment "A polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand. An agrochemical fungicide, it is used to control a variety of diseases including blight, leaf spot, rust, downy mildew and scab." ;
rdfs:subClassOf obo:CHEBI_60027 .
obo:GO_0046667 a rdfs:Class ;
rdfs:label "compound eye retinal cell programmed cell death" ;
rdfs:comment "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium." ;
rdfs:subClassOf obo:GO_0046666 .
obo:CL_4307092 a rdfs:Class ;
rdfs:label "COP NN_1 Rgcc committed oligodendrocyte precursor (Mmus)" ;
rdfs:comment "A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bmp4 (Mmus), Zfp36l1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Rgcc, Plpp4. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5272 COP NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301611 .
obo:CHEBI_34999 a rdfs:Class ;
rdfs:label "teicoplanin A3-1" ;
rdfs:comment "A glycopeptide consisting of a macropolycyclic heptapeptide in which a phenolic hydroxy group has been converted to its α-D-mannoside while a secondary alcohol group has been converted to the corresponding 2-acetamido-2-deoxy-β-D-glucoside." ;
rdfs:subClassOf obo:CHEBI_22160 , obo:CHEBI_24396 , obo:CHEBI_26191 , obo:CHEBI_26195 , obo:CHEBI_35618 , obo:CHEBI_51026 , obo:CHEBI_83403 .
obo:GO_1901166 a rdfs:Class ;
rdfs:label "neural crest cell migration involved in autonomic nervous system development" ;
rdfs:comment "Any neural crest cell migration that is involved in autonomic nervous system development." ;
rdfs:subClassOf obo:GO_0001755 .
obo:GO_0001839 a rdfs:Class ;
rdfs:label "neural plate morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0016331 .
obo:GO_0050912 a rdfs:Class ;
rdfs:label "detection of chemical stimulus involved in sensory perception of taste" ;
rdfs:comment "The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0009593 , obo:GO_0050907 .
obo:PHIPO_0000772 a rdfs:Class ;
rdfs:label "sensitive to cefotetan"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefotetan. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CL_0000234 a rdfs:Class ;
rdfs:label "phagocyte" ;
rdfs:comment "Any cell capable of ingesting particulate matter via phagocytosis." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000219 , obo:CL_0000325 .
obo:UBERON_0002553 a rdfs:Class ;
rdfs:label "anatomical cavity" ;
rdfs:comment "Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0019228 a rdfs:Class ;
rdfs:label "neuronal action potential" ;
rdfs:comment "An action potential that occurs in a neuron." ;
rdfs:subClassOf obo:GO_0001508 .
obo:CHEBI_17359 a rdfs:Class ;
rdfs:label "sulfite" ;
rdfs:comment "A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3)." ;
rdfs:subClassOf obo:CHEBI_33482 , obo:CHEBI_48154 , obo:CHEBI_79388 .
obo:PHIPO_0000382 a rdfs:Class ;
rdfs:label "resistance to diethofencarb"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to diethofencarb. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000236 a rdfs:Class ;
rdfs:label "pathogen host interaction localization phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the localization of a structure or substance in a cell." ;
rdfs:subClassOf obo:PHIPO_0000510 .
obo:PHIPO_0000896 a rdfs:Class ;
rdfs:label "sensitive to spiroxamine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to spiroxamine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0002457 a rdfs:Class ;
rdfs:label "T cell antigen processing and presentation" ;
rdfs:comment "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." ;
rdfs:subClassOf obo:GO_0019882 .
obo:PHIPO_0000122 a rdfs:Class ;
rdfs:label "abnormal endospore formation"@en ;
rdfs:comment "A reproductive phenotype where the process of endospore formation, in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell is abnormal. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions. (GO:0034301)" ;
rdfs:subClassOf obo:PHIPO_0000078 .
obo:GO_0031642 a rdfs:Class ;
rdfs:label "negative regulation of myelination" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons." ;
rdfs:subClassOf obo:GO_0031641 , obo:GO_0031645 , obo:GO_0048523 , obo:GO_0065007 .
obo:PHIPO_0000289 a rdfs:Class ;
rdfs:label "obsolete altered colour" .
obo:PR_000001809 a rdfs:Class ;
rdfs:label "CD59-like glycoprotein" ;
rdfs:comment "A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_7660 a rdfs:Class ;
rdfs:label "nystatin" ;
rdfs:comment "A heterogeneous mixture of polyene compounds produced by cultures of Streptomyces noursei. It mainly consists of three biologically active components designated nystatin A1, nystatin A2, and nystatin A3. It is used to treat oral and dermal fungal infections." ;
rdfs:subClassOf obo:CHEBI_22507 , obo:CHEBI_25105 , obo:CHEBI_26191 , obo:CHEBI_36244 , obo:CHEBI_48121 , obo:CHEBI_60004 , obo:CHEBI_87113 .
obo:UBERON_0010345 a rdfs:Class ;
rdfs:label "4th arch mesenchyme from head mesenchyme" ;
rdfs:comment "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005691 , obo:UBERON_0010360 .
obo:GO_1902115 a rdfs:Class ;
rdfs:label "regulation of organelle assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of organelle assembly." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0044087 , obo:GO_0065007 .
obo:CHEBI_16705 a rdfs:Class ;
rdfs:label "6-aminopenicillanic acid" ;
rdfs:comment "A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and pharmacologic characteristics." ;
rdfs:subClassOf obo:CHEBI_25865 .
obo:GO_0060037 a rdfs:Class ;
rdfs:label "pharyngeal system development" ;
rdfs:comment "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the structure it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:GO_0006811 a rdfs:Class ;
rdfs:label "monoatomic ion transport" ;
rdfs:comment "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ;
rdfs:subClassOf obo:GO_0006810 .
obo:CHEBI_61739 a rdfs:Class ;
rdfs:label "aureobasidin A" ;
rdfs:comment "A cyclodepsipeptide antibiotic, which is isolated from the filamentous fungus Aureobasidium pullulans R106 and is toxic to yeast at low concentrations (0.1-0.5 ug/ml)." ;
rdfs:subClassOf obo:CHEBI_25903 , obo:CHEBI_35213 .
obo:NCBITaxon_33511 a rdfs:Class ;
rdfs:label "Deuterostomia" ;
rdfs:subClassOf obo:NCBITaxon_33213 .
obo:CHEBI_2468 a rdfs:Class ;
rdfs:label "secondary alpha-hydroxy ketone" ;
rdfs:comment "An α-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing one hydrogen and one organyl group. Secondary α-hydroxy ketones are also known as acyloins, and are formally derived from reductive coupling of two carboxylic acid groups." ;
rdfs:subClassOf obo:CHEBI_139588 , obo:CHEBI_35681 .
obo:GO_1900247 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translational elongation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation." ;
rdfs:subClassOf obo:GO_0006448 , obo:GO_0065007 .
obo:CHEBI_33429 a rdfs:Class ;
rdfs:label "monoatomic monoanion" ;
rdfs:subClassOf obo:CHEBI_23905 , obo:CHEBI_36830 .
obo:PHIPO_0000325 a rdfs:Class ;
rdfs:label "obsolete gain of effector of pathogenicity suppression of host defense" ;
rdfs:comment "The pathogen effector entity has gained the ability to suppress host defense." .
obo:UBERON_0000468 a rdfs:Class ;
rdfs:label "multicellular organism" ;
rdfs:comment "Anatomical structure that is an individual member of a species and consists of more than one cell." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:GO_0070265 a rdfs:Class ;
rdfs:label "obsolete necrotic cell death" ;
rdfs:comment "OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues." .
a rdfs:Class ;
rdfs:label "Pineal body" ;
rdfs:subClassOf , obo:UBERON_0001905 .
obo:GO_0060404 a rdfs:Class ;
rdfs:label "axonemal microtubule depolymerization" ;
rdfs:comment "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." ;
rdfs:subClassOf obo:GO_0007019 , obo:GO_0010938 , obo:GO_0061523 .
obo:PHIPO_0000935 a rdfs:Class ;
rdfs:label "decreased cell wall integrity"@en ;
rdfs:comment "A cellular process phenotype in which the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall is decreased." ;
rdfs:subClassOf obo:PHIPO_0000925 .
obo:UBERON_0002067 a rdfs:Class ;
rdfs:label "dermis" ;
rdfs:comment "The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]." ;
rdfs:subClassOf obo:UBERON_0010314 , obo:UBERON_0013754 .
obo:BSPO_0000108 a rdf:Property ;
rdfs:range .
obo:GO_0060415 a rdfs:Class ;
rdfs:label "muscle tissue morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function." ;
rdfs:subClassOf obo:GO_0048729 .
obo:GO_1903409 a rdfs:Class ;
rdfs:label "reactive oxygen species biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0072593 .
obo:GO_0060959 a rdfs:Class ;
rdfs:label "cardiac neuron development" ;
rdfs:comment "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state." ;
rdfs:subClassOf obo:GO_0048468 , obo:GO_0048935 , obo:GO_0055006 .
obo:UBERON_0005337 a rdfs:Class ;
rdfs:label "outflow tract of ventricle" ;
rdfs:comment "A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]." ;
rdfs:subClassOf obo:UBERON_0004145 .
obo:CHEBI_47811 a rdfs:Class ;
rdfs:label "penamcarboxylate" ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:GO_0097026 a rdfs:Class ;
rdfs:label "dendritic cell dendrite assembly" ;
rdfs:comment "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0120031 .
obo:GO_0007405 a rdfs:Class ;
rdfs:label "neuroblast proliferation" ;
rdfs:comment "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0061351 .
obo:GO_0071870 a rdfs:Class ;
rdfs:label "cellular response to catecholamine stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_0071868 , obo:GO_0071869 , obo:GO_1901701 .
obo:GO_0140694 a rdfs:Class ;
rdfs:label "membraneless organelle assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0070925 .
obo:UBERON_0006934 a rdfs:Class ;
rdfs:label "sensory epithelium" ;
rdfs:comment "Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0000488 .
obo:GO_1905148 a rdfs:Class ;
rdfs:label "negative regulation of smooth muscle hypertrophy" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy." ;
rdfs:subClassOf obo:GO_0014741 , obo:GO_0014745 , obo:GO_0065007 , obo:GO_1905147 .
obo:UBERON_0005563 a rdfs:Class ;
rdfs:label "trigeminal neural crest" ;
rdfs:comment "Cranial neural crest which gives rise to the trigeminal ganglion." ;
rdfs:subClassOf obo:UBERON_0003099 , obo:UBERON_0005253 , obo:UBERON_0007530 .
obo:CHEBI_26878 a rdfs:Class ;
rdfs:label "tertiary alcohol" ;
rdfs:comment "A tertiary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:UBERON_0008231 a rdfs:Class ;
rdfs:label "dorsal thoracic segment of trunk" ;
rdfs:comment "Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax." ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:GO_0021695 a rdfs:Class ;
rdfs:label "cerebellar cortex development" ;
rdfs:comment "The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0060534 a rdfs:Class ;
rdfs:label "trachea cartilage development" ;
rdfs:comment "The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0051216 .
obo:CHEBI_25750 a rdfs:Class ;
rdfs:label "oxime" ;
rdfs:comment "Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes." ;
rdfs:subClassOf obo:CHEBI_50860 , obo:CHEBI_51143 .
obo:UBERON_0008114 a rdfs:Class ;
rdfs:label "joint of girdle" ;
rdfs:comment "A skeletal joint that is part of a appendage girdle region." ;
rdfs:subClassOf obo:UBERON_0000982 .
obo:GO_0051101 a rdfs:Class ;
rdfs:label "regulation of DNA binding" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)." ;
rdfs:subClassOf obo:GO_0051098 , obo:GO_0065007 .
obo:PR_Q8VCC9 a rdfs:Class ;
rdfs:label "spondin-1 (mouse)" ;
rdfs:comment "A spondin-1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000015557 , obo:PR_000029032 .
obo:PHIPO_0000924 a rdfs:Class ;
rdfs:label "host defense-induced oxidative burst level phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, which affects a pathogen induced host oxidative burst level (GO:0002679)." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:CHEBI_45615 a rdfs:Class ;
rdfs:label "salicylhydroxamic acid" ;
rdfs:comment "A hydroxamic acid that is N-hydroxybenzamide carrying a phenolic hydroxy group at position 2." ;
rdfs:subClassOf obo:CHEBI_24650 , obo:CHEBI_33853 .
obo:UBERON_0000015 a rdfs:Class ;
rdfs:label "non-material anatomical boundary" ;
rdfs:comment "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." ;
rdfs:subClassOf obo:UBERON_0000466 .
obo:CHEBI_29699 a rdfs:Class ;
rdfs:label "tunicamycin" ;
rdfs:comment "A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety." ;
rdfs:subClassOf obo:CHEBI_60004 .
obo:PHIPO_0000761 a rdfs:Class ;
rdfs:label "sensitive to valinomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to valinomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_28600 a rdfs:Class ;
rdfs:label "farnesol" ;
rdfs:comment "A farnesane sesquiterpenoid that is dodeca-2,6,10-triene substituted by methyl groups at positions 3, 7 and 11 and a hydroxy group at position 1." ;
rdfs:subClassOf obo:CHEBI_15734 , obo:CHEBI_26199 , obo:CHEBI_36757 .
obo:CL_4033015 a rdfs:Class ;
rdfs:label "retinal astrocyte" ;
rdfs:comment "A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons." ;
rdfs:subClassOf obo:CL_0000127 , obo:CL_0009004 .
obo:CHEBI_184376 a rdfs:Class ;
rdfs:label "streptidine(2+)" ;
rdfs:comment "A guanidinium ion obtained by protonation of both guanidino groups of streptidine; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_60251 .
obo:GO_0010608 a rdfs:Class ;
rdfs:label "post-transcriptional regulation of gene expression" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." ;
rdfs:subClassOf obo:GO_0010468 .
obo:GO_0036195 a rdfs:Class ;
rdfs:label "muscle cell projection membrane" ;
rdfs:comment "The portion of the plasma membrane surrounding a muscle cell projection." ;
rdfs:subClassOf obo:GO_0031253 .
obo:PHIPO_0000433 a rdfs:Class ;
rdfs:label "normal catalytic activity"@en ;
rdfs:comment "A single species molecular function phenotype in which the observed rate and other catalytic properties of a specified catalytic activity are normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000432 .
obo:GO_0014042 a rdfs:Class ;
rdfs:label "positive regulation of neuron maturation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuron maturation." ;
rdfs:subClassOf obo:GO_0014041 , obo:GO_0065007 , obo:GO_1903431 .
obo:CL_0011026 a rdfs:Class ;
rdfs:label "progenitor cell" ;
rdfs:comment "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." ;
rdfs:subClassOf obo:CL_0011115 .
obo:CHEBI_32872 a rdfs:Class ;
rdfs:label "prolinium" ;
rdfs:comment "An α-amino-acid cation that is the conjugate acid of proline, arising from protonation of the amino group." ;
rdfs:subClassOf obo:CHEBI_33719 .
obo:GO_0048627 a rdfs:Class ;
rdfs:label "myoblast development" ;
rdfs:comment "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:GO_0014909 a rdfs:Class ;
rdfs:label "smooth muscle cell migration" ;
rdfs:comment "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism." ;
rdfs:subClassOf obo:GO_0014812 , obo:GO_0016477 .
obo:UBERON_0002546 a rdfs:Class ;
rdfs:label "cranial placode" ;
rdfs:comment "Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic." ;
rdfs:subClassOf obo:UBERON_0005085 .
obo:CHEBI_79092 a rdfs:Class ;
rdfs:label "EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor" ;
rdfs:comment "An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any such enzyme using H2O2 as acceptor and incorporating one oxygen atom of the H2O2 into the product (EC 1.11.2.*)." ;
rdfs:subClassOf obo:CHEBI_76738 .
obo:CL_4310094 a rdfs:Class ;
rdfs:label "GPe SOX6-CTXND1 GABA prototypic neuron (Primate)" ;
rdfs:comment "A prototypic neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe SOX6-CTXND1 GABA." ;
rdfs:subClassOf obo:CL_0020009 .
obo:GO_2000765 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic translation." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:UBERON_0013700 a rdfs:Class ;
rdfs:label "axial musculature" ;
rdfs:comment "Musculature of the head and neck, spine, and ribs." ;
rdfs:subClassOf obo:UBERON_0001015 .
obo:PHIPO_0000262 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction endocytosis" ;
rdfs:comment "A pathogen host interaction (cellular process???) phenotype in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." .
obo:UBERON_0003685 a rdfs:Class ;
rdfs:label "cranial suture" ;
rdfs:comment "Fibrous joint in which the articulating bones or cartilages of the skull are connected by sutural ligaments (scant amount of collagenous dense connective tissue). Examples: sagittal suture, frontal suture." ;
rdfs:subClassOf obo:UBERON_0002209 , obo:UBERON_0009198 .
obo:PHIPO_0000180 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction DNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is abnormal, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:UBERON_0009617 a rdfs:Class ;
rdfs:label "head paraxial mesoderm" ;
rdfs:comment "Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles." ;
rdfs:subClassOf obo:UBERON_0005253 .
obo:UBERON_0007691 a rdfs:Class ;
rdfs:label "gustatory pore" ;
rdfs:comment "The minute opening of a taste bud on the surface of the oral mucosa through which the gustatory hairs of the specialised neuroepithelial gustatory cells project." ;
rdfs:subClassOf obo:UBERON_0000161 .
obo:UBERON_0029004 a rdfs:Class ;
rdfs:label "striosomal part of caudate nucleus" ;
rdfs:subClassOf obo:UBERON_0027371 .
obo:GO_1903224 a rdfs:Class ;
rdfs:label "regulation of endodermal cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endodermal cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:GO_0014029 a rdfs:Class ;
rdfs:label "neural crest formation" ;
rdfs:comment "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." ;
rdfs:subClassOf obo:GO_0001837 , obo:GO_0048646 .
obo:GO_0061049 a rdfs:Class ;
rdfs:label "cell growth involved in cardiac muscle cell development" ;
rdfs:comment "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." ;
rdfs:subClassOf obo:GO_0016049 , obo:GO_0048588 .
obo:UBERON_0004364 a rdfs:Class ;
rdfs:label "ectoplacental cone" ;
rdfs:comment "Thickened trophoblast of the blastocyst in rodents that becomes the fetal portion of the placenta." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:CL_1000298 a rdfs:Class ;
rdfs:label "mesothelial cell of dura mater" ;
rdfs:comment "A mesothelial cell that is part of the dura mater." ;
rdfs:subClassOf obo:CL_0000077 , obo:CL_0002319 .
obo:PHIPO_0000841 a rdfs:Class ;
rdfs:label "sensitive to cefuroxime"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefuroxime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_36963 a rdfs:Class ;
rdfs:label "organooxygen compound" ;
rdfs:comment "An organochalcogen compound containing at least one carbon-oxygen bond." ;
rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_36962 .
obo:GO_0006720 a rdfs:Class ;
rdfs:label "isoprenoid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." ;
rdfs:subClassOf obo:GO_0006629 .
obo:CHEBI_33273 a rdfs:Class ;
rdfs:label "polyatomic anion" ;
rdfs:comment "An anion consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_36358 .
obo:PHIPO_0001344 a rdfs:Class ;
rdfs:label "normal growth on triflumizole" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to triflumizole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0048634 a rdfs:Class ;
rdfs:label "regulation of muscle organ development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of muscle development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:PHIPO_0000348 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction catalytic activity phenotype" ;
rdfs:comment "A pathogen host interaction phenotype which affects a catalytic activity." .
obo:GO_0009112 a rdfs:Class ;
rdfs:label "nucleobase metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0055086 .
obo:UBERON_0010192 a rdfs:Class ;
rdfs:label "genital artery" ;
rdfs:comment "One of the laterally paired arteries that supply the gonads." ;
rdfs:subClassOf obo:UBERON_0004573 , obo:UBERON_0012254 .
obo:GO_2001026 a rdfs:Class ;
rdfs:label "regulation of endothelial cell chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis." ;
rdfs:subClassOf obo:GO_0010594 , obo:GO_0050920 , obo:GO_0065007 .
obo:CL_0002375 a rdfs:Class ;
rdfs:label "Schwann cell precursor" ;
rdfs:comment "A multipotent progenitor cell that develops from a migratory neural crest cell. The schwann cell precursor is embedded among axons, with minimal extracellular space separating them from nerve cell membranes. This cell lacks a basal lamina, which distinguishes it from more mature Schwann cells. In rodents, cadherin-19 (Cdh19) serves as a specific marker for this developmental stage." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0011026 .
obo:CHEBI_29192 a rdfs:Class ;
rdfs:label "hydrogenperoxide(1-)" ;
rdfs:subClassOf obo:CHEBI_33693 .
obo:CHEBI_38104 a rdfs:Class ;
rdfs:label "oxacycle" ;
rdfs:comment "Any organic heterocyclic compound containing at least one ring oxygen atom." ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_36963 .
obo:PHIPO_0001127 a rdfs:Class ;
rdfs:label "decreased growth on myristic acid carbon source"@en ;
rdfs:comment "A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing myristic acid as the carbon source." ;
rdfs:subClassOf obo:PHIPO_0001216 .
obo:PHIPO_0000904 a rdfs:Class ;
rdfs:label "sensitive to sulbactam"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulbactam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_74818 a rdfs:Class ;
rdfs:label "heteroaryl hydroxy compound" ;
rdfs:comment "Any organic aromatic compound having one or more hydroxy groups attached to a heteroarene ring." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_33822 .
obo:GO_0045732 a rdfs:Class ;
rdfs:label "positive regulation of protein catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0042176 , obo:GO_0051247 , obo:GO_0065007 .
obo:PHIPO_0000827 a rdfs:Class ;
rdfs:label "sensitive to nicotinamide"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to nicotinamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0099536 a rdfs:Class ;
rdfs:label "synaptic signaling" ;
rdfs:comment "Cell-cell signaling to, from or within a synapse." ;
rdfs:subClassOf obo:GO_0007267 .
obo:GO_0006446 a rdfs:Class ;
rdfs:label "regulation of translational initiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translational initiation." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:PHIPO_0001252 a rdfs:Class ;
rdfs:label "decreased pathogen tissue to tissue migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally from tissue to tissue within the host organism is decreased." ;
rdfs:subClassOf obo:PHIPO_0001159 .
obo:GO_0045836 a rdfs:Class ;
rdfs:label "positive regulation of meiotic nuclear division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of meiosis." ;
rdfs:subClassOf obo:GO_0040020 , obo:GO_0051446 , obo:GO_0051785 , obo:GO_0065007 , obo:GO_0090068 .
obo:CHEBI_64133 a rdfs:Class ;
rdfs:label "EC 2.5.1.58 (protein farnesyltransferase) inhibitor" ;
rdfs:comment "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group." ;
rdfs:subClassOf obo:CHEBI_76663 .
obo:GO_0031503 a rdfs:Class ;
rdfs:label "protein-containing complex localization" ;
rdfs:comment "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0033036 , obo:GO_0051179 .
obo:GO_0006860 a rdfs:Class ;
rdfs:label "extracellular amino acid transport" ;
rdfs:comment "The directed extracellular movement of amino acids." ;
rdfs:subClassOf obo:GO_0006858 , obo:GO_0006865 .
obo:GO_0006139 a rdfs:Class ;
rdfs:label "nucleobase-containing compound metabolic process" ;
rdfs:comment "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0044238 .
obo:CL_0010020 a rdfs:Class ;
rdfs:label "cardiac glial cell" ;
rdfs:comment "Any glial cell that is part of some heart." ;
rdfs:subClassOf obo:CL_0000125 , obo:CL_0002494 .
obo:UBERON_0001062 a rdfs:Class ;
rdfs:label "anatomical entity" ;
rdfs:comment "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ;
rdfs:subClassOf obo:BFO_0000004 .
obo:UBERON_0007719 a rdfs:Class ;
rdfs:label "bone of reproductive organ" ;
rdfs:comment "A bone that is part of a reproductive organ." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0005156 .
obo:CHEBI_30802 a rdfs:Class ;
rdfs:label "isophthalic acid" ;
rdfs:comment "A benzenedicarboxylic acid that is benzene substituted by carboxy groups at position 1 and 3. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and terephthalic acids." ;
rdfs:subClassOf obo:CHEBI_26094 .
obo:UBERON_0004794 a rdfs:Class ;
rdfs:label "esophagus secretion" ;
rdfs:comment "A secretion that is part of a esophagus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000456 .
obo:PATO_0001241 a rdfs:Class ;
rdfs:label "physical object quality" ;
rdfs:comment "A quality which inheres in a continuant." ;
rdfs:subClassOf obo:PATO_0000001 .
obo:GO_0006940 a rdfs:Class ;
rdfs:label "regulation of smooth muscle contraction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of smooth muscle contraction." ;
rdfs:subClassOf obo:GO_0006937 , obo:GO_0065007 .
obo:PHIPO_0001076 a rdfs:Class ;
rdfs:label "growth auxotrophic for lysine"@en ;
rdfs:comment "A growth phenotype which describes an individual or a population of organisms which requires lysine for growth. Auxotrophy usually results from a cell's inability to synthesize the compound." ;
rdfs:subClassOf obo:PHIPO_0001075 .
obo:PHIPO_0001015 a rdfs:Class ;
rdfs:label "decreased level of host defense-induced callose deposition"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host produced callose deposition usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:GO_0048870 a rdfs:Class ;
rdfs:label "cell motility" ;
rdfs:comment "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0002888 a rdfs:Class ;
rdfs:label "positive regulation of myeloid leukocyte mediated immunity" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity." ;
rdfs:subClassOf obo:GO_0002705 , obo:GO_0002886 , obo:GO_0065007 .
obo:PHIPO_0000414 a rdfs:Class ;
rdfs:label "abnormal unicellular population growth"@en ;
rdfs:comment "A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is lesser or greater than normal." ;
rdfs:subClassOf obo:PHIPO_0000162 .
obo:GO_0005326 a rdfs:Class ;
rdfs:label "neurotransmitter transmembrane transporter activity" ;
rdfs:comment "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." ;
rdfs:subClassOf obo:GO_0022857 .
obo:CL_0000839 a rdfs:Class ;
rdfs:label "myeloid lineage restricted progenitor cell" ;
rdfs:comment "A progenitor cell restricted to the myeloid lineage." ;
rdfs:subClassOf obo:CL_0002031 , obo:CL_0011026 .
obo:CHEBI_24866 a rdfs:Class ;
rdfs:label "salt" ;
rdfs:comment "A salt is an assembly of cations and anions." ;
rdfs:subClassOf obo:CHEBI_37577 .
obo:UBERON_0003078 a rdfs:Class ;
rdfs:label "epibranchial placode" ;
rdfs:comment "Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia." ;
rdfs:subClassOf obo:UBERON_0009955 .
obo:PHIPO_0000093 a rdfs:Class ;
rdfs:label "obsolete abnormal parthenogenesis" .
obo:GO_0050909 a rdfs:Class ;
rdfs:label "sensory perception of taste" ;
rdfs:comment "The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process." ;
rdfs:subClassOf obo:GO_0007606 .
obo:GO_0042127 a rdfs:Class ;
rdfs:label "regulation of cell population proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell proliferation." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0110021 a rdfs:Class ;
rdfs:label "cardiac muscle myoblast proliferation" ;
rdfs:comment "The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0051450 .
obo:GO_0098958 a rdfs:Class ;
rdfs:label "retrograde axonal transport of mitochondrion" ;
rdfs:comment "The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0008090 , obo:GO_0019896 .
obo:CL_1001509 a rdfs:Class ;
rdfs:label "glycinergic neuron" ;
rdfs:comment "The neurons that utilize glycine as a neurotransmitter." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000540 .
obo:CHEBI_46883 a rdfs:Class ;
rdfs:label "carboxy group" ;
rdfs:subClassOf obo:CHEBI_33249 .
obo:CHEBI_38131 a rdfs:Class ;
rdfs:label "lactol" ;
rdfs:comment "Cyclic hemiacetals formed by intramolecular addition of a hydroxy group to an aldehydic or ketonic carbonyl group. They are thus 1-oxacycloalkan-2-ols or unsaturated analogues." ;
rdfs:subClassOf obo:CHEBI_5653 .
obo:GO_1905922 a rdfs:Class ;
rdfs:label "negative regulation of acetylcholine biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0065007 , obo:GO_1905921 .
obo:PHIPO_0000422 a rdfs:Class ;
rdfs:label "altered carbohydrate binding specificity"@en ;
rdfs:comment "A single species phenotype in which a gene product that normally binds to a specific carbohydrate instead binds to a different carbohydrate when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000419 .
obo:GO_0035905 a rdfs:Class ;
rdfs:label "ascending aorta development" ;
rdfs:comment "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CL_4307068 a rdfs:Class ;
rdfs:label "Tanycyte NN_2 Otx2 tanycyte (Mmus)" ;
rdfs:comment "A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ccdc146 (Mmus), Tbx3 (Mmus), Otx2 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Otx2, Nkx2-4. These cells are located in the Hypothalamus, brain , in or close to the regions: Periventricular hypothalamic nucleus, posterior part, third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5248 Tanycyte NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301603 .
obo:UBERON_0004275 a rdfs:Class ;
rdfs:label "third ventricle choroid plexus epithelium" ;
rdfs:comment "A choroid plexus epithelium that is part of a third ventricle [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003911 .
obo:GO_0016595 a rdfs:Class ;
rdfs:label "glutamate binding" ;
rdfs:comment "Binding to glutamate, the anion of 2-aminopentanedioic acid." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0016597 , obo:GO_0031406 .
obo:CL_0000700 a rdfs:Class ;
rdfs:label "dopaminergic neuron" ;
rdfs:comment "A neuron that releases dopamine as a neurotransmitter." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_4033050 .
obo:UBERON_0009583 a rdfs:Class ;
rdfs:label "spinal cord mantle layer" ;
rdfs:subClassOf obo:UBERON_0004061 .
obo:CL_4310126 a rdfs:Class ;
rdfs:label "STR-BF TAC3-PLPP4-LHX8 GABA TAC3-positive striatal interneuron (Primate)" ;
rdfs:comment "A TAC3-positive striatal interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR-BF TAC3-PLPP4-LHX8 GABA." ;
rdfs:subClassOf obo:CL_4042001 .
obo:GO_0060977 a rdfs:Class ;
rdfs:label "coronary vasculature morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048514 .
obo:PHIPO_0000750 a rdfs:Class ;
rdfs:label "sensitive to aztreonam"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to aztreonam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PR_Q6R6I7 a rdfs:Class ;
rdfs:label "relaxin receptor 1 (mouse)" ;
rdfs:comment "A relaxin receptor 1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001666 , obo:PR_000029032 .
obo:PHIPO_0000533 a rdfs:Class ;
rdfs:label "resistance to gramicidin D"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to gramicidin D. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_39209 a rdfs:Class ;
rdfs:label "macrolide insecticide" ;
rdfs:subClassOf obo:CHEBI_39221 .
obo:CHEBI_55373 a rdfs:Class ;
rdfs:label "isoxazoles" ;
rdfs:comment "Oxazoles in which the N and O atoms are adjacent." ;
rdfs:subClassOf obo:CHEBI_35790 .
obo:CHEBI_47519 a rdfs:Class ;
rdfs:label "ketoconazole" ;
rdfs:comment "A racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-ketoconazole." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87069 , obo:CHEBI_87071 .
obo:PHIPO_0000063 a rdfs:Class ;
rdfs:label "sexual spores present"@en ;
rdfs:comment "A reproductive phenotype where asexual spores are present (FAO:0000017). The product of meiosis." ;
rdfs:subClassOf obo:PHIPO_0000079 .
obo:CL_4307028 a rdfs:Class ;
rdfs:label "Astro-NT NN_1 Galnt15 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Galnt15 (Mmus), Agt (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Galnt15. These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5208 Astro-NT NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301589 .
obo:PHIPO_0001167 a rdfs:Class ;
rdfs:label "pathogen modulation of host immune system process phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype that affects a host immune system process during pathogen infection (GO:0002376)." ;
rdfs:subClassOf obo:PHIPO_0001173 .
obo:PHIPO_0001322 a rdfs:Class ;
rdfs:label "resistance to flumorph"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to flumorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0140352 a rdfs:Class ;
rdfs:label "export from cell" ;
rdfs:comment "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 .
obo:UBERON_0002016 a rdfs:Class ;
rdfs:label "pulmonary vein" ;
rdfs:comment "Pulmonary veins are blood vessels that transport blood from the lungs to the heart[GO]." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0013768 .
obo:CHEBI_27311 a rdfs:Class ;
rdfs:label "volatile oil component" ;
rdfs:comment "Any plant metabolite that is found naturally as a component of a volatile oil." ;
rdfs:subClassOf obo:CHEBI_76924 .
obo:CHEBI_17499 a rdfs:Class ;
rdfs:label "hydrogen donor" ;
rdfs:comment "A molecular entity that can undergo oxidation by the loss of hydrogen atom(s)." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:CL_0002599 a rdfs:Class ;
rdfs:label "smooth muscle cell of the esophagus" ;
rdfs:comment "A smooth muscle cell of the esophagus." ;
rdfs:subClassOf obo:CL_0000192 .
obo:GO_0060093 a rdfs:Class ;
rdfs:label "negative regulation of synaptic transmission, glycinergic" ;
rdfs:comment "Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." ;
rdfs:subClassOf obo:GO_0050805 , obo:GO_0060092 , obo:GO_0065007 .
obo:UBERON_0003100 a rdfs:Class ;
rdfs:label "female organism" ;
rdfs:comment "Gonochoristic organism that can produce female gametes." ;
rdfs:subClassOf obo:UBERON_0000468 .
obo:PHIPO_0000328 a rdfs:Class ;
rdfs:label "normal cellular component organization"@en ;
rdfs:comment "A cellular process phenotype in which any process of cellular component organization at the cellular level is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000407 .
obo:GO_0034101 a rdfs:Class ;
rdfs:label "erythrocyte homeostasis" ;
rdfs:comment "Any process of regulating the production and elimination of erythrocytes within an organism." ;
rdfs:subClassOf obo:GO_0002262 , obo:GO_0048872 .
obo:CHEBI_83688 a rdfs:Class ;
rdfs:label "(R)-fenarimol" ;
rdfs:comment "A (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol that has R configuration." ;
rdfs:subClassOf obo:CHEBI_83686 .
obo:CL_4042019 a rdfs:Class ;
rdfs:label "beta1-tanycyte"@en ;
rdfs:comment "A type of tanycyte located in ventral part of the lateral wall of the third ventricle and in the lateral infundibular recess of the brain. This tanycyte has an elongated morphology with multiple microvilli extending into the median eminence. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH)." ;
rdfs:subClassOf obo:CL_0002085 , obo:CL_1100001 .
obo:GO_0031274 a rdfs:Class ;
rdfs:label "positive regulation of pseudopodium assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia." ;
rdfs:subClassOf obo:GO_0031272 , obo:GO_0065007 , obo:GO_0120034 .
obo:CHEBI_64769 a rdfs:Class ;
rdfs:label "organic cationic group" ;
rdfs:comment "A cationic group that contains carbon." ;
rdfs:subClassOf obo:CHEBI_64766 .
obo:UBERON_0002352 a rdfs:Class ;
rdfs:label "atrioventricular node" ;
rdfs:comment "An area of conducting tissue between the atria and the ventricles of the heart that conducts the normal electrical impulse from the atria to the ventricles." ;
rdfs:subClassOf obo:UBERON_0004491 , obo:UBERON_0004493 , obo:UBERON_0010131 .
obo:GO_0060900 a rdfs:Class ;
rdfs:label "embryonic camera-type eye formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PHIPO_0001203 a rdfs:Class ;
rdfs:label "obsolete gain of functional pathogen effector" ;
rdfs:comment "A phenotype where the ability of a pathogen effector to produce an infectious disease is acquired." .
obo:PHIPO_0001455 a rdfs:Class ;
rdfs:label "accelerated host-defense induced lesion formation by host hypersensitive response"@en ;
rdfs:comment "A phenotype where there is an accelerated process of host tissue cell death, leading to the formation of a host lesion, which is induced by the host activating its own hypersensitive response in defense against a pathogen." ;
rdfs:subClassOf obo:PHIPO_0000192 .
obo:GO_0045200 a rdfs:Class ;
rdfs:label "establishment of neuroblast polarity" ;
rdfs:comment "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." ;
rdfs:subClassOf obo:GO_0030010 , obo:GO_0045196 .
obo:UBERON_0034708 a rdfs:Class ;
rdfs:label "cerebellum marginal layer" ;
rdfs:subClassOf obo:UBERON_0004062 , obo:UBERON_0034709 .
obo:GO_0098722 a rdfs:Class ;
rdfs:label "asymmetric stem cell division" ;
rdfs:comment "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity." ;
rdfs:subClassOf obo:GO_0008356 , obo:GO_0017145 .
obo:GO_0043603 a rdfs:Class ;
rdfs:label "amide metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0002366 a rdfs:Class ;
rdfs:label "leukocyte activation involved in immune response" ;
rdfs:comment "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0002263 , obo:GO_0045321 .
obo:PHIPO_0001390 a rdfs:Class ;
rdfs:label "normal growth on pyrisoxazole" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrisoxazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:UBERON_0000107 a rdfs:Class ;
rdfs:label "cleavage stage" ;
rdfs:comment "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:RO_0002087 a rdf:Property ;
rdfs:label "immediately preceded by"@en ;
rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:BFO_0000062 .
obo:GO_0040016 a rdfs:Class ;
rdfs:label "embryonic cleavage" ;
rdfs:comment "The first few specialized divisions of an activated animal egg." ;
rdfs:subClassOf obo:GO_0051301 .
obo:CHEBI_34043 a rdfs:Class ;
rdfs:label "1,2-phenylenediamine" ;
rdfs:comment "A phenylenediamine in which the two amino groups are ortho to each other." ;
rdfs:subClassOf obo:CHEBI_17499 , obo:CHEBI_51402 .
obo:UBERON_0004367 a rdfs:Class ;
rdfs:label "Descemet's membrane" ;
rdfs:comment "A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]." ;
rdfs:subClassOf obo:UBERON_0005769 .
obo:UBERON_0003288 a rdfs:Class ;
rdfs:label "meninx of midbrain" ;
rdfs:comment "A meninx that is part of a midbrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002360 , obo:UBERON_0003547 .
obo:CHEBI_33465 a rdfs:Class ;
rdfs:label "elemental pnictogen" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_33259 , obo:CHEBI_33302 .
obo:GO_0050803 a rdfs:Class ;
rdfs:label "regulation of synapse structure or activity" ;
rdfs:comment "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ;
rdfs:subClassOf obo:GO_0065008 .
obo:PR_Q00342 a rdfs:Class ;
rdfs:label "receptor-type tyrosine-protein kinase FLT3 (mouse)" ;
rdfs:comment "A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000002001 , obo:PR_000029032 .
obo:UBERON_0016545 a rdfs:Class ;
rdfs:label "pharyngeal ectoderm" ;
rdfs:comment "The external part of the developing pharynx that is made of ectoderm. During vertebrate development, pockets form in pharyngeal ectoderm between the pharyngeal arches." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0003351 , obo:UBERON_0005291 .
obo:GO_0016528 a rdfs:Class ;
rdfs:label "sarcoplasm" ;
rdfs:comment "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum." ;
rdfs:subClassOf obo:GO_0005737 .
obo:PHIPO_0000137 a rdfs:Class ;
rdfs:label "increased protein-protein interaction"@en ;
rdfs:comment "A single species molecular function phenotype in which the binding of one protein to another occurs to a greater extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000133 .
obo:PHIPO_0000386 a rdfs:Class ;
rdfs:label "resistance to naftifine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to naftifine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001232 a rdfs:Class ;
rdfs:label "pathogen RNA within host present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen RNA usually present during host infection is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001267 .
obo:GO_0090160 a rdfs:Class ;
rdfs:label "Golgi to lysosome transport" ;
rdfs:comment "The directed movement of substances from the Golgi to lysosomes." ;
rdfs:subClassOf obo:GO_0006896 , obo:GO_0007041 , obo:GO_0016192 , obo:GO_0016482 .
obo:GO_0045724 a rdfs:Class ;
rdfs:label "positive regulation of cilium assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the formation of a cilium." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120034 , obo:GO_1902017 , obo:GO_1902117 .
obo:NCBITaxon_10066 a rdfs:Class ;
rdfs:label "Muridae" ;
rdfs:subClassOf obo:NCBITaxon_337687 .
obo:UBERON_0018321 a rdfs:Class ;
rdfs:label "foramen for glossopharyngeal nerve" ;
rdfs:comment "Foramen that allows the passge of the glossopharyngeal nerve (cranial nerve IX)." ;
rdfs:subClassOf obo:UBERON_0013685 .
obo:GO_1902904 a rdfs:Class ;
rdfs:label "negative regulation of supramolecular fiber organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1902903 .
obo:CHEBI_36828 a rdfs:Class ;
rdfs:label "pseudohalide anion" ;
rdfs:subClassOf obo:CHEBI_36829 .
obo:UBERON_0002726 a rdfs:Class ;
rdfs:label "cervical spinal cord" ;
rdfs:comment "A spinal cord segment that adjacent_to a cervical region." ;
rdfs:subClassOf obo:UBERON_0005844 .
obo:CHEBI_132502 a rdfs:Class ;
rdfs:label "fatty acid 18:3" ;
rdfs:comment "Any trienoic fatty acid containing 18 carbons." ;
rdfs:subClassOf obo:CHEBI_73155 .
obo:GO_0099637 a rdfs:Class ;
rdfs:label "neurotransmitter receptor transport" ;
rdfs:comment "The directed movement of neurotransmitter receptors." ;
rdfs:subClassOf obo:GO_0015031 , obo:GO_0031503 .
obo:GO_0015870 a rdfs:Class ;
rdfs:label "acetylcholine transport" ;
rdfs:comment "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0071705 , obo:GO_1901374 .
obo:CHEBI_3639 a rdfs:Class ;
rdfs:label "chlorothalonil" ;
rdfs:comment "A dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops." ;
rdfs:subClassOf obo:CHEBI_26888 , obo:CHEBI_51308 , obo:CHEBI_87034 .
obo:GO_0003360 a rdfs:Class ;
rdfs:label "brainstem development" ;
rdfs:comment "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0021801 a rdfs:Class ;
rdfs:label "cerebral cortex radial glia-guided migration" ;
rdfs:comment "The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex." ;
rdfs:subClassOf obo:GO_0021799 , obo:GO_0022030 .
obo:UBERON_0010042 a rdfs:Class ;
rdfs:label "1st arch mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a pharyngeal arch 1." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0009494 .
obo:CHEBI_27283 a rdfs:Class ;
rdfs:label "very long-chain fatty acid" ;
rdfs:comment "A fatty acid which has a chain length greater than C22. Very long-chain fatty acids which have a chain length greater than C27 are also known as ultra-long-chain fatty acids." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:UBERON_0014775 a rdfs:Class ;
rdfs:label "prosomere" ;
rdfs:comment "A neuromere that is part of the presumptive forebrain." ;
rdfs:subClassOf obo:UBERON_0004731 .
obo:GO_0060458 a rdfs:Class ;
rdfs:label "right lung development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect." ;
rdfs:subClassOf obo:GO_0030324 , obo:GO_0048856 .
obo:CHEBI_64237 a rdfs:Class ;
rdfs:label "EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor" ;
rdfs:comment "An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins." ;
rdfs:subClassOf obo:CHEBI_76816 .
obo:GO_0042981 a rdfs:Class ;
rdfs:label "regulation of apoptotic process" ;
rdfs:comment "Any process that modulates the occurrence or rate of cell death by apoptotic process." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0065007 .
obo:PHIPO_0000670 a rdfs:Class ;
rdfs:label "resistance to levofloxacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to levofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0060132 a rdfs:Class ;
rdfs:label "prolactin secreting cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:UBERON_0008307 a rdfs:Class ;
rdfs:label "heart endothelium" ;
rdfs:comment "An endothelium that is part of a heart [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0004852 .
obo:GO_0010623 a rdfs:Class ;
rdfs:label "programmed cell death involved in cell development" ;
rdfs:comment "The activation of endogenous cellular processes that result in the death of a cell as part of its development." ;
rdfs:subClassOf obo:GO_0012501 , obo:GO_0048869 .
obo:CHEBI_77053 a rdfs:Class ;
rdfs:label "closantel" ;
rdfs:comment "A racemate comprising equimolar amounts of (R)- and (S)-clostanel. An anthelmintic, it is used (as the dihydrate of the sodium salt) in veterinary medicine for the treatment of fluke and nematode infections." ;
rdfs:subClassOf obo:CHEBI_50860 , obo:CHEBI_60911 .
obo:GO_0043167 a rdfs:Class ;
rdfs:label "ion binding" ;
rdfs:comment "Binding to an ion, a charged atoms or groups of atoms." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0036094 .
obo:CL_0000413 a rdfs:Class ;
rdfs:label "haploid cell" ;
rdfs:comment "A cell whose nucleus contains a single haploid genome." ;
rdfs:subClassOf obo:CL_0000000 .
obo:CHEBI_33670 a rdfs:Class ;
rdfs:label "heteromonocyclic compound" ;
rdfs:subClassOf obo:CHEBI_33661 , obo:CHEBI_5686 .
obo:GO_1905332 a rdfs:Class ;
rdfs:label "positive regulation of morphogenesis of an epithelium" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_1905330 .
obo:PHIPO_0001117 a rdfs:Class ;
rdfs:label "host immune signaling pathway activated by pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the host immune signaling pathway is induced by a pathogen." ;
rdfs:subClassOf obo:PHIPO_0001116 .
obo:UBERON_0011860 a rdfs:Class ;
rdfs:label "collection of collagen fibrils" ;
rdfs:subClassOf obo:UBERON_0000476 .
obo:CHEBI_30762 a rdfs:Class ;
rdfs:label "salicylate" ;
rdfs:comment "A monohydroxybenzoate that is the conjugate base of salicylic acid." ;
rdfs:subClassOf obo:CHEBI_25388 .
obo:PHIPO_0000644 a rdfs:Class ;
rdfs:label "resistance to streptomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to streptomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0010191 a rdfs:Class ;
rdfs:label "aortic system" ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:GO_1904706 a rdfs:Class ;
rdfs:label "negative regulation of vascular associated smooth muscle cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0048662 , obo:GO_0065007 , obo:GO_1904705 .
obo:UBERON_0005243 a rdfs:Class ;
rdfs:label "interventricular septum endocardium" ;
rdfs:comment "An endocardium that is part of a interventricular septum [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002165 .
obo:UBERON_0004160 a rdfs:Class ;
rdfs:label "proepicardium" ;
rdfs:comment "An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium." ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:PATO_0000297 a rdfs:Class ;
rdfs:label "arrested" ;
rdfs:comment "A quality of a process which ends earlier than the natural end time or reference process." ;
rdfs:subClassOf obo:PATO_0002052 , obo:PATO_0002324 .
obo:CHEBI_23955 a rdfs:Class ;
rdfs:label "erythronolide" ;
rdfs:subClassOf obo:CHEBI_25106 .
obo:GO_0002251 a rdfs:Class ;
rdfs:label "organ or tissue specific immune response" ;
rdfs:comment "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues." ;
rdfs:subClassOf obo:GO_0006955 .
obo:UBERON_0003416 a rdfs:Class ;
rdfs:label "mesenchyme of tongue" ;
rdfs:comment "Mesenchyme that is part of a developing tongue [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:PHIPO_0000723 a rdfs:Class ;
rdfs:label "sensitive to pyrazinecarboxamide"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrazinecarboxamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_50503 a rdfs:Class ;
rdfs:label "laxative" ;
rdfs:comment "An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:CHEBI_30938 a rdfs:Class ;
rdfs:label "6-aminopenicillanate" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:CHEBI_50893 a rdfs:Class ;
rdfs:label "azaarene" ;
rdfs:subClassOf obo:CHEBI_33833 , obo:CHEBI_38101 .
obo:PHIPO_0000604 a rdfs:Class ;
rdfs:label "resistance to meropenem"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to meropenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000693 .
obo:GO_0019098 a rdfs:Class ;
rdfs:label "reproductive behavior" ;
rdfs:comment "The specific behavior of an organism that is associated with reproduction." ;
rdfs:subClassOf obo:GO_0007610 , obo:GO_0048609 .
obo:UBERON_0006002 a rdfs:Class ;
rdfs:label "vitelline artery" ;
rdfs:comment "The paired arteries that carry blood to the yolk sac from the dorsal aorta." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0004365 .
obo:GO_0072201 a rdfs:Class ;
rdfs:label "negative regulation of mesenchymal cell proliferation" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0010464 , obo:GO_0065007 .
obo:CHEBI_71300 a rdfs:Class ;
rdfs:label "EC 2.* (transferase) inhibitor" ;
rdfs:comment "An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)" ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:CHEBI_75771 a rdfs:Class ;
rdfs:label "mouse metabolite" ;
rdfs:comment "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." ;
rdfs:subClassOf obo:CHEBI_75768 .
obo:GO_0071322 a rdfs:Class ;
rdfs:label "cellular response to carbohydrate stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." ;
rdfs:subClassOf obo:GO_0009743 , obo:GO_0070887 , obo:GO_1901701 .
obo:GO_1904937 a rdfs:Class ;
rdfs:label "sensory neuron migration" ;
rdfs:comment "The orderly movement of a sensory neuron from one site to another." ;
rdfs:subClassOf obo:GO_0001764 , obo:GO_0016477 .
obo:PHIPO_0001243 a rdfs:Class ;
rdfs:label "pathogen binding of chitin with host absent"@en ;
rdfs:comment "A molecular function phenotype in which the binding of chitin or chitin fragments by the pathogen during host colonization is absent." ;
rdfs:subClassOf obo:PHIPO_0000164 .
obo:UBERON_0000095 a rdfs:Class ;
rdfs:label "cardiac neural crest" ;
rdfs:comment "Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]." ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:GO_1903849 a rdfs:Class ;
rdfs:label "positive regulation of aorta morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of aorta morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903847 , obo:GO_1905653 .
obo:CHEBI_33917 a rdfs:Class ;
rdfs:label "aldohexose" ;
rdfs:comment "A hexose with a (potential) aldehyde group at one end." ;
rdfs:subClassOf obo:CHEBI_15693 , obo:CHEBI_18133 .
obo:PHIPO_0000053 a rdfs:Class ;
rdfs:label "delayed asexual sporulation"@en ;
rdfs:comment "A reproductive phenotype in which the occurrence of asexual spore formation happens later than normal." ;
rdfs:subClassOf obo:PHIPO_0000078 .
obo:GO_0048086 a rdfs:Class ;
rdfs:label "negative regulation of developmental pigmentation" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ;
rdfs:subClassOf obo:GO_0048070 , obo:GO_0048519 , obo:GO_0065007 .
obo:GO_1905140 a rdfs:Class ;
rdfs:label "regulation of apical ectodermal ridge formation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0065007 .
obo:GO_1903626 a rdfs:Class ;
rdfs:label "positive regulation of DNA catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of DNA catabolic process." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0051054 , obo:GO_0065007 , obo:GO_1903624 .
obo:CL_0000783 a rdfs:Class ;
rdfs:label "multinucleated phagocyte" ;
rdfs:comment "A phagocyte formed by the fusion of mononuclear phagocytes." ;
rdfs:subClassOf obo:CL_0000228 , obo:CL_0000518 .
obo:COB_0000021 a rdfs:Class ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:GO_0009584 a rdfs:Class ;
rdfs:label "detection of visible light" ;
rdfs:comment "The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." ;
rdfs:subClassOf obo:GO_0009583 .
obo:GO_0048318 a rdfs:Class ;
rdfs:label "axial mesoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." ;
rdfs:subClassOf obo:GO_0007498 , obo:GO_0048856 .
obo:PHIPO_0000339 a rdfs:Class ;
rdfs:label "decreased pathogen cell to cell migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is decreased compared to normal." ;
rdfs:subClassOf obo:PHIPO_0000334 .
obo:GO_0046833 a rdfs:Class ;
rdfs:label "positive regulation of RNA export from nucleus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0032241 , obo:GO_0046824 , obo:GO_0046831 , obo:GO_0065007 .
obo:PATO_0001375 a rdfs:Class ;
rdfs:label "haploid" ;
rdfs:comment "A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes." ;
rdfs:subClassOf obo:PATO_0001393 .
obo:PHIPO_0000494 a rdfs:Class ;
rdfs:label "secondary metabolic process phenotype"@en ;
rdfs:comment "A single organism phenotype that affects the chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." ;
rdfs:subClassOf obo:PHIPO_0000492 .
obo:CHEBI_59836 a rdfs:Class ;
rdfs:label "oxo fatty acid anion" ;
rdfs:comment "A fatty acid anion carrying one or more oxo substituents" ;
rdfs:subClassOf obo:CHEBI_28868 , obo:CHEBI_35903 .
obo:CHEBI_39220 a rdfs:Class ;
rdfs:label "avermectin pesticide" ;
rdfs:subClassOf obo:CHEBI_39221 .
obo:CL_4310137 a rdfs:Class ;
rdfs:label "STRv D1 NUDAP MSN D1-NUDAP medium spiny neuron (Primate)" ;
rdfs:comment "A D1-NUDAP medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D1 NUDAP MSN." ;
rdfs:subClassOf obo:CL_4030050 , obo:CL_4030054 .
obo:GO_1902018 a rdfs:Class ;
rdfs:label "negative regulation of cilium assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120033 , obo:GO_1902017 , obo:GO_1902116 .
obo:GO_0021989 a rdfs:Class ;
rdfs:label "olfactory cortex development" ;
rdfs:comment "The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_32845 a rdfs:Class ;
rdfs:label "serinate" ;
rdfs:comment "An α-amino-acid anion that is the conjugate base of serine." ;
rdfs:subClassOf obo:CHEBI_33558 .
obo:CL_0002320 a rdfs:Class ;
rdfs:label "connective tissue cell" ;
rdfs:comment "A cell of the supporting or framework tissue of the body, which includes adipose tissue, cartilage, and bone. In vertebrates, this cell arises chiefly from the embryonic mesoderm and, in cranial regions, from neural crest." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:CL_0002551 a rdfs:Class ;
rdfs:label "fibroblast of dermis" ;
rdfs:comment "Any skin fibroblast that is part of some dermis." ;
rdfs:subClassOf obo:CL_0002620 .
obo:CL_4310120 a rdfs:Class ;
rdfs:label "STR FS PTHLH-PVALB GABA striatal pthlh-expressing interneuron (Primate)" ;
rdfs:comment "A striatal pthlh-expressing interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR FS PTHLH-PVALB GABA." ;
rdfs:subClassOf obo:CL_4042023 .
obo:UBERON_8440012 a rdfs:Class ;
rdfs:label "cerebral nuclei" ;
rdfs:comment "One of three components of the cerebrum that is a composite structure of the endbrain defined on the basis of origin from the ventricular ridge of the embryonic Encephalon. It consists of the extended striatum and the extended pallidum." ;
rdfs:subClassOf obo:UBERON_0009663 .
obo:GO_1905075 a rdfs:Class ;
rdfs:label "positive regulation of tight junction disassembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of tight junction disassembly." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1905073 .
obo:UBERON_0007617 a rdfs:Class ;
rdfs:label "synovial cavity of joint" ;
rdfs:comment "An anatomical cavity that surrounded_by a synovial joint." ;
rdfs:subClassOf obo:UBERON_0002553 .
obo:CHEBI_25189 a rdfs:Class ;
rdfs:label "1,4-dimercaptobutane-2,3-diol" ;
rdfs:comment "A glycol that is butane-2,3-diol in which a hydrogen from each of the methyl groups is replaced by a thiol group." ;
rdfs:subClassOf obo:CHEBI_13643 , obo:CHEBI_22944 , obo:CHEBI_29256 .
obo:UBERON_0022317 a rdfs:Class ;
rdfs:label "olfactory cortex layer 1" ;
rdfs:comment "Surface layer of the olfactory cortex that contains dendrites, fiber systems and a small number of neurons. It has been divided into a superficial part and a deep part." ;
rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0022303 .
obo:GO_0003007 a rdfs:Class ;
rdfs:label "heart morphogenesis" ;
rdfs:comment "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:GO_0150078 a rdfs:Class ;
rdfs:label "positive regulation of neuroinflammatory response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuroinflammatory response." ;
rdfs:subClassOf obo:GO_0050729 , obo:GO_0065007 , obo:GO_0150077 .
obo:GO_0032179 a rdfs:Class ;
rdfs:label "germ tube" ;
rdfs:comment "The slender tubular outgrowth first produced by most spores in germination." ;
rdfs:subClassOf obo:GO_0110165 .
obo:PHIPO_0001156 a rdfs:Class ;
rdfs:label "increased level of pathogen reactive oxygen species production within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen produced reactive oxygen species (ROS) usually present during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001197 .
obo:PHIPO_0000618 a rdfs:Class ;
rdfs:label "resistance to streptomycin sulfate"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to streptomycin sulfate. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0002088 a rdfs:Class ;
rdfs:label "lens development in camera-type eye" ;
rdfs:comment "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0036093 a rdfs:Class ;
rdfs:label "germ cell proliferation" ;
rdfs:comment "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population." ;
rdfs:subClassOf obo:GO_0008283 .
obo:CHEBI_37948 a rdfs:Class ;
rdfs:label "oxaspiro compound" ;
rdfs:comment "A spiro compound in which at least one of the cyclic components is an oxygen heterocyle." ;
rdfs:subClassOf obo:CHEBI_33599 .
obo:GO_0098641 a rdfs:Class ;
rdfs:label "cadherin binding involved in cell-cell adhesion" ;
rdfs:comment "Any cadherin binding that occurs as part of the process of cell-cell adhesion." ;
rdfs:subClassOf obo:GO_0045296 , obo:GO_0098632 .
obo:GO_1905292 a rdfs:Class ;
rdfs:label "regulation of neural crest cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neural crest cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000736 .
obo:UBERON_0029001 a rdfs:Class ;
rdfs:label "matrix compartment of caudate nucleus" ;
rdfs:comment "Matrix compartment located in the caudate nucleus." ;
rdfs:subClassOf obo:UBERON_0027368 .
obo:CHEBI_30751 a rdfs:Class ;
rdfs:label "formic acid" ;
rdfs:comment "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects." ;
rdfs:subClassOf obo:CHEBI_25384 .
obo:CHEBI_24782 a rdfs:Class ;
rdfs:label "imide" ;
rdfs:subClassOf obo:CHEBI_33257 .
obo:PHIPO_0001228 a rdfs:Class ;
rdfs:label "pathogen reactive oxygen species production within host present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen produced reactive oxygen species (ROS) usually present during infection is present as normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001197 .
obo:UBERON_0003079 a rdfs:Class ;
rdfs:label "floor plate" ;
rdfs:comment "The specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube." ;
rdfs:subClassOf obo:UBERON_0000119 , obo:UBERON_0004121 , obo:UBERON_0005291 .
obo:BSPO_0015102 a rdf:Property ;
rdfs:range .
obo:CL_0000188 a rdfs:Class ;
rdfs:label "cell of skeletal muscle" ;
rdfs:comment "A somatic cell located in skeletal muscle." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:UBERON_0011300 a rdfs:Class ;
rdfs:label "gray matter of telencephalon" ;
rdfs:comment "A portion of gray matter that is part of a telencephalon." ;
rdfs:subClassOf obo:UBERON_0002020 , obo:UBERON_0019264 .
obo:GO_0038187 a rdfs:Class ;
rdfs:label "pattern recognition receptor activity" ;
rdfs:comment "Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response." ;
rdfs:subClassOf obo:GO_0038023 .
obo:GO_0003331 a rdfs:Class ;
rdfs:label "positive regulation of extracellular matrix constituent secretion" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells." ;
rdfs:subClassOf obo:GO_0003330 , obo:GO_0065007 , obo:GO_1903055 , obo:GO_1903532 .
obo:UBERON_0002097 a rdfs:Class ;
rdfs:label "skin of body" ;
rdfs:comment "The organ covering the body that consists of the dermis and epidermis." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0010314 .
obo:UBERON_0004708 a rdfs:Class ;
rdfs:label "paired limb/fin" ;
rdfs:comment "An appendage that is part of an appendage girdle complex." ;
rdfs:subClassOf obo:UBERON_0000026 , obo:UBERON_0010314 .
obo:GO_0005585 a rdfs:Class ;
rdfs:label "collagen type II trimer" ;
rdfs:comment "A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils." ;
rdfs:subClassOf obo:GO_0005583 .
obo:GO_1904014 a rdfs:Class ;
rdfs:label "response to serotonin" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_0071867 , obo:GO_1901700 .
obo:GO_0051674 a rdfs:Class ;
rdfs:label "localization of cell" ;
rdfs:comment "Any process in which a cell is transported to, and/or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0051179 .
obo:GO_0044293 a rdfs:Class ;
rdfs:label "dendriole" ;
rdfs:comment "Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC)." ;
rdfs:subClassOf obo:GO_0044292 .
obo:UBERON_0002213 a rdfs:Class ;
rdfs:label "cartilaginous joint" ;
rdfs:comment "Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA]." ;
rdfs:subClassOf obo:UBERON_0011134 .
obo:CHEBI_75763 a rdfs:Class ;
rdfs:label "eukaryotic metabolite" ;
rdfs:comment "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:PATO_0001993 a rdfs:Class ;
rdfs:label "multicellular" ;
rdfs:comment "A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell." ;
rdfs:subClassOf obo:PATO_0001992 .
a rdfs:Class ;
rdfs:label "Cerebellar cortex, molecular layer" ;
rdfs:subClassOf , obo:UBERON_0002974 .
obo:BSPO_0001100 a rdf:Property ;
rdfs:range .
obo:GO_0098975 a rdfs:Class ;
rdfs:label "postsynapse of neuromuscular junction" ;
rdfs:comment "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma." ;
rdfs:subClassOf obo:GO_0098794 .
obo:GO_2000668 a rdfs:Class ;
rdfs:label "regulation of dendritic cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000106 .
obo:PATO_0001031 a rdfs:Class ;
rdfs:label "elasticity" ;
rdfs:comment "A physical quality inhering in a bearer by virtue of the bearer's disposition to recover its size and shape after deformation in any way." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:PHIPO_0000633 a rdfs:Class ;
rdfs:label "resistance to tigecycline"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tigecycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0099083 a rdfs:Class ;
rdfs:label "retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission" ;
rdfs:comment "Modulation of synaptic transmission by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide." ;
rdfs:subClassOf obo:GO_0099082 , obo:GO_0099537 , obo:GO_0099551 .
obo:GO_0042166 a rdfs:Class ;
rdfs:label "acetylcholine binding" ;
rdfs:comment "Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0043169 .
obo:UBERON_0016550 a rdfs:Class ;
rdfs:label "spinal cord column" ;
rdfs:subClassOf obo:UBERON_0011215 .
obo:CL_0000357 a rdfs:Class ;
rdfs:label "stratified epithelial stem cell" ;
rdfs:subClassOf obo:CL_0000036 .
obo:CHEBI_29688 a rdfs:Class ;
rdfs:label "telithromycin" ;
rdfs:subClassOf obo:CHEBI_28963 .
obo:CHEBI_33284 a rdfs:Class ;
rdfs:label "nutrient" ;
rdfs:comment "A nutrient is a food component that an organism uses to survive and grow." ;
rdfs:subClassOf obo:CHEBI_78295 .
obo:PR_000001177 a rdfs:Class ;
rdfs:label "D(2) dopamine receptor" ;
rdfs:comment "A D(2)-like dopamine receptor that is a translation product of the human DRD2 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001108 .
obo:CHEBI_83759 a rdfs:Class ;
rdfs:label "(2S,3R)-epoxiconazole" ;
rdfs:comment "The (2S,3R)-stereoisomer of 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole." ;
rdfs:subClassOf obo:CHEBI_83758 .
obo:PHIPO_0000811 a rdfs:Class ;
rdfs:label "sensitive to teicoplanin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to teicoplanin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000567 a rdfs:Class ;
rdfs:label "resistance to mancozeb"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to mancozeb. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_48407 a rdfs:Class ;
rdfs:label "antiparkinson drug" ;
rdfs:comment "A drug used in the treatment of Parkinson's disease." ;
rdfs:subClassOf obo:CHEBI_66956 .
obo:GO_0045900 a rdfs:Class ;
rdfs:label "negative regulation of translational elongation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." ;
rdfs:subClassOf obo:GO_0006448 , obo:GO_0017148 , obo:GO_0065007 .
obo:CL_2000010 a rdfs:Class ;
rdfs:label "dermis blood vessel endothelial cell" ;
rdfs:comment "Any blood vessel endothelial cell that is part of a dermis." ;
rdfs:subClassOf obo:CL_0000071 .
obo:CL_0005000 a rdfs:Class ;
rdfs:label "spinal cord interneuron" ;
rdfs:comment "A CNS interneuron located in the spinal cord." ;
rdfs:subClassOf obo:CL_0000099 .
a rdfs:Class .
obo:CHEBI_18085 a rdfs:Class .
obo:UBERON_0001708 a rdfs:Class ;
rdfs:label "jaw skeleton" ;
rdfs:comment "Subdivision of skeleton which includes upper and lower jaw skeletons." ;
rdfs:subClassOf obo:UBERON_0010314 , obo:UBERON_0010912 .
obo:GO_0045604 a rdfs:Class ;
rdfs:label "regulation of epidermal cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of epidermal cell differentiation." ;
rdfs:subClassOf obo:GO_0030856 , obo:GO_0045682 , obo:GO_0065007 .
obo:PHIPO_0001311 a rdfs:Class ;
rdfs:label "normal growth on chlorothalonil"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to chlorothalonil (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PHIPO_0000569 a rdfs:Class ;
rdfs:label "resistance to netilmicin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to netilmicin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0061938 a rdfs:Class ;
rdfs:label "protein localization to somatodendritic compartment" ;
rdfs:comment "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment." ;
rdfs:subClassOf obo:GO_0008104 .
obo:PHIPO_0001124 a rdfs:Class ;
rdfs:label "decreased growth on erucic acid carbon source"@en ;
rdfs:comment "A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing erucic acid as the carbon source." ;
rdfs:subClassOf obo:PHIPO_0001216 .
obo:GO_0042379 a rdfs:Class ;
rdfs:label "chemokine receptor binding" ;
rdfs:comment "Binding to a chemokine receptor." ;
rdfs:subClassOf obo:GO_0001664 , obo:GO_0005126 , obo:GO_0005488 .
obo:UBERON_0007383 a rdfs:Class ;
rdfs:label "enveloping layer of ectoderm" ;
rdfs:comment "Outermost layer of cells surrounding the embryo." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0005291 .
obo:PR_P05555 a rdfs:Class ;
rdfs:label "integrin alpha-M (mouse)" ;
rdfs:comment "An integrin alpha-M that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001012 , obo:PR_000029032 .
obo:CHEBI_50247 a rdfs:Class ;
rdfs:label "antidote" ;
rdfs:comment "Any protective agent counteracting or neutralizing the action of poisons." ;
rdfs:subClassOf obo:CHEBI_50267 .
obo:UBERON_0003129 a rdfs:Class ;
rdfs:label "skull" ;
rdfs:comment "Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]." ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:CL_0000307 a rdfs:Class ;
rdfs:label "tracheal epithelial cell" ;
rdfs:comment "An epithelial cell found in the trachea." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002202 .
obo:UBERON_0001950 a rdfs:Class ;
rdfs:label "neocortex" ;
rdfs:comment "An area of cerebral cortex defined on the basis of cytoarchitecture that have six layers. Starting from the cortical surface the layers are: molecular layer (I), external granular layer (II), external pyramidal layer (III), internal granular layer (IV), internal pyramidal layer (V), and multiform layer (VI). Neocortex is most prominent in the frontal lobe, the parietal lobe, the temporal lobe and the occipital lobe, less so in the cingulate gyrus, the parahippocampal gyrus and the insula. It is composed of two subdivisions: true isocortex and proisocortex (Carpenter-83)(NN)." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_0019755 a rdfs:Class ;
rdfs:label "one-carbon compound transport" ;
rdfs:comment "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 .
obo:CHEBI_35488 a rdfs:Class ;
rdfs:label "central nervous system depressant" ;
rdfs:comment "A loosely defined group of drugs that tend to reduce the activity of the central nervous system." ;
rdfs:subClassOf obo:CHEBI_35470 .
obo:UBERON_0002075 a rdfs:Class ;
rdfs:label "viscus" ;
rdfs:comment "An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0005177 .
obo:UBERON_0003610 a rdfs:Class ;
rdfs:label "heart elastic tissue" ;
rdfs:comment "The type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers." ;
rdfs:subClassOf obo:UBERON_0002521 , obo:UBERON_0003613 , obo:UBERON_0003837 .
obo:GO_0021576 a rdfs:Class ;
rdfs:label "hindbrain formation" ;
rdfs:comment "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CL_1001576 a rdfs:Class ;
rdfs:label "oral mucosa squamous cell" ;
rdfs:comment "Squamous cell of oral epithelium." ;
rdfs:subClassOf obo:CL_0000076 , obo:CL_0002251 .
obo:BFO_0000141 a rdfs:Class .
obo:CHEBI_81763 a rdfs:Class ;
rdfs:label "fludioxonil" ;
rdfs:comment "A member of the class of benzodioxoles that is 2,2-difluoro-1,3-benzodioxole substituted at position 4 by a 3-cyanopyrrol-4-yl group. A fungicide seed treatment for control of a range of diseases including Fusarium, Rhizoctonia and Alternaria ." ;
rdfs:subClassOf obo:CHEBI_18379 , obo:CHEBI_26455 , obo:CHEBI_37143 , obo:CHEBI_38298 .
obo:PHIPO_0001268 a rdfs:Class ;
rdfs:label "presence of host gall during pathogen invasion"@en ;
rdfs:comment "A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in the abnormal growth of the host tissue, forming a plant gall (BTO:0005833 plant gall)." ;
rdfs:subClassOf obo:PHIPO_0001006 .
obo:NCBITaxon_32525 a rdfs:Class ;
rdfs:label "Theria " ;
rdfs:subClassOf obo:NCBITaxon_40674 .
obo:CHEBI_24995 a rdfs:Class ;
rdfs:label "lactam" ;
rdfs:comment "Cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." ;
rdfs:subClassOf obo:CHEBI_23443 , obo:CHEBI_37622 , obo:CHEBI_38101 .
obo:GO_2000810 a rdfs:Class ;
rdfs:label "regulation of bicellular tight junction assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of tight junction assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901888 .
obo:PATO_0002325 a rdfs:Class ;
rdfs:label "onset quality" ;
rdfs:comment "The temporal relation between the start of the process with respect to a reference process." ;
rdfs:subClassOf obo:PATO_0002323 .
obo:CHEBI_5100 a rdfs:Class ;
rdfs:label "flucytosine" ;
rdfs:comment "An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections." ;
rdfs:subClassOf obo:CHEBI_37143 , obo:CHEBI_38337 , obo:CHEBI_38338 , obo:CHEBI_60783 , obo:CHEBI_87205 .
obo:GO_0043253 a rdfs:Class ;
rdfs:label "chloroplast ribosome" ;
rdfs:comment "A ribosome contained within a chloroplast." ;
rdfs:subClassOf obo:GO_0005840 , obo:GO_0009547 .
obo:PHIPO_0000655 a rdfs:Class ;
rdfs:label "resistance to salicylhydroxamic acid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to salicylhydroxamic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_55323 a rdfs:Class ;
rdfs:label "antidiarrhoeal drug" ;
rdfs:comment "Any drug found useful in the symptomatic treatment of diarrhoea." ;
rdfs:subClassOf obo:CHEBI_55324 .
obo:GO_0048029 a rdfs:Class ;
rdfs:label "monosaccharide binding" ;
rdfs:comment "Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." ;
rdfs:subClassOf obo:GO_0030246 , obo:GO_0036094 .
obo:GO_0046822 a rdfs:Class ;
rdfs:label "regulation of nucleocytoplasmic transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0065007 .
obo:PHIPO_0000031 a rdfs:Class ;
rdfs:label "abnormal pathogen growth after penetration of the barrier" ;
rdfs:comment "A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is abnormal (i.e indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000160 .
obo:CHEBI_29922 a rdfs:Class ;
rdfs:label "sulfo group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:GO_0060926 a rdfs:Class ;
rdfs:label "cardiac pacemaker cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0055013 .
obo:CHEBI_52898 a rdfs:Class ;
rdfs:label "azamacrocycle" ;
rdfs:comment "A cyclic macromolecule containing one or more nitrogen atoms in place of carbon either as the divalent group NH for the group CH2 or a single trivalent nitrogen atom for the group CH." ;
rdfs:subClassOf obo:CHEBI_51026 .
obo:GO_2000379 a rdfs:Class ;
rdfs:label "positive regulation of reactive oxygen species metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0065007 , obo:GO_2000377 .
obo:GO_1905523 a rdfs:Class ;
rdfs:label "positive regulation of macrophage migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of macrophage migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0071677 , obo:GO_1905521 .
a rdfs:Class ;
rdfs:label "Periventricular zone" ;
rdfs:subClassOf , obo:UBERON_0002271 .
obo:CHEBI_132130 a rdfs:Class ;
rdfs:label "hydroxyquinone" ;
rdfs:comment "Any quinone in which one or more of the carbons making up the quinone moiety is substituted by a hydroxy group." ;
rdfs:subClassOf obo:CHEBI_33822 , obo:CHEBI_36141 .
obo:PHIPO_0001191 a rdfs:Class ;
rdfs:label "presence of melanin accumulation in pathogen asexual spore within host"@en ;
rdfs:comment "A pathogen host interaction, in which the accumulation of melanin within a pathogen asexual spore, usually present during infection, is present." ;
rdfs:subClassOf obo:PHIPO_0001080 .
obo:CHEBI_53634 a rdfs:Class ;
rdfs:label "neomycin C" ;
rdfs:comment "A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine C." ;
rdfs:subClassOf obo:CHEBI_47779 .
obo:CHEBI_33692 a rdfs:Class ;
rdfs:label "hydrides" ;
rdfs:comment "Hydrides are chemical compounds of hydrogen with other chemical elements." ;
rdfs:subClassOf obo:CHEBI_33608 , obo:CHEBI_37577 .
obo:GO_0014019 a rdfs:Class ;
rdfs:label "neuroblast development" ;
rdfs:comment "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:CL_4307054 a rdfs:Class ;
rdfs:label "Astro-OLF NN_2 Alk astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Chrdl1 (Mmus), Sfrp1 (Mmus), Atp13a4 (Mmus). It is distinguished from other Astro-OLF NN_2 cells by expression of Alk, Atp13a4. These cells are located in the Olfactory areas , in or close to the regions: Anterior olfactory nucleus, Main olfactory bulb, granule layer, Main olfactory bulb, mitral layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5234 Astro-OLF NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301597 .
obo:PR_000001128 a rdfs:Class ;
rdfs:label "chemokine receptor" ;
rdfs:comment "A rhodopsin-like G-protein coupled receptor that in active form binds to one or more chemokines." ;
rdfs:subClassOf obo:PR_000001094 .
obo:PHIPO_0001116 a rdfs:Class ;
rdfs:label "host immune system signaling pathway pathogen-host interaction phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype that affects a host immune system signaling pathway during pathogen infection." ;
rdfs:subClassOf obo:PHIPO_0001167 .
obo:CHEBI_87064 a rdfs:Class ;
rdfs:label "benzimidazolylcarbamate fungicide" ;
rdfs:comment "Any carbamate fungicide that contains a benzimidazolyl group attached to the nitrogen of the carbamate moiety." ;
rdfs:subClassOf obo:CHEBI_22715 , obo:CHEBI_87061 .
obo:GO_0010663 a rdfs:Class ;
rdfs:label "positive regulation of striated muscle cell apoptotic process" ;
rdfs:comment "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." ;
rdfs:subClassOf obo:GO_0010661 , obo:GO_0010662 , obo:GO_0065007 .
obo:GO_0065003 a rdfs:Class ;
rdfs:label "protein-containing complex assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0043933 .
obo:CHEBI_33238 a rdfs:Class ;
rdfs:label "monoatomic entity" ;
rdfs:comment "A monoatomic entity is a molecular entity consisting of a single atom." ;
rdfs:subClassOf obo:CHEBI_33259 .
obo:PR_000001332 a rdfs:Class ;
rdfs:label "cell adhesion molecule CEACAM8" ;
rdfs:comment "A protein that is a translation product of the human CEACAM8 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0005388 a rdfs:Class ;
rdfs:label "photoreceptor array" ;
rdfs:comment "An array of photoreceptors and any supporting cells found in an eye." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:PHIPO_0000622 a rdfs:Class ;
rdfs:label "resistance to erythromycin A"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to erythromycin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_59772 a rdfs:Class ;
rdfs:label "hemiketal" ;
rdfs:comment "A hemiacetal having the structure RR1C(OH)OR2 (R, R1, R2 ≠ H), derived from a ketone by formal addition of an alcohol to the carbonyl group." ;
rdfs:subClassOf obo:CHEBI_5653 .
obo:CL_0000223 a rdfs:Class ;
rdfs:label "endodermal cell" ;
rdfs:comment "A cell of the inner of the three germ layers of the embryo." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0002321 .
obo:PHIPO_0000692 a rdfs:Class ;
rdfs:label "resistance to penicillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to penicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0003853 a rdfs:Class ;
rdfs:label "spinal cord neural crest" ;
rdfs:comment "A neural crest that has_potential_to_developmentally_contribute_to a spinal cord." ;
rdfs:subClassOf obo:UBERON_0002342 .
obo:UBERON_0010299 a rdfs:Class ;
rdfs:label "scleral mesenchyme" ;
rdfs:comment "Mesenchyme surrounding the developing optic cup which develops into the sclera." ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:CHEBI_57726 a rdfs:Class ;
rdfs:label "D-proline zwitterion" ;
rdfs:comment "A D-α-amino acid zwitterion that is D-proline in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_59871 .
obo:CL_0000518 a rdfs:Class ;
rdfs:label "phagocyte (sensu Vertebrata)" ;
rdfs:comment "A phagocyte in vertebrates that is able to phagocytosis." ;
rdfs:subClassOf obo:CL_0000234 , obo:CL_0000255 .
obo:CHEBI_87205 a rdfs:Class ;
rdfs:label "pyrimidine antifungal drug" ;
rdfs:comment "Any pyrimidine antifungal agent that has been used for the treatment of fungal infections in humans or animals." ;
rdfs:subClassOf obo:CHEBI_87204 .
obo:UBERON_0000122 a rdfs:Class ;
rdfs:label "neuron projection bundle" ;
rdfs:comment "A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." ;
rdfs:subClassOf obo:UBERON_0005162 .
obo:UBERON_0018649 a rdfs:Class ;
rdfs:label "cardiac muscle tissue of ventricle" ;
rdfs:subClassOf obo:UBERON_0001133 , obo:UBERON_0004493 .
obo:CHEBI_35515 a rdfs:Class ;
rdfs:label "5alpha-cholestane" ;
rdfs:comment "The 5α-stereoisomer of cholestane." ;
rdfs:subClassOf obo:CHEBI_35516 .
obo:GO_0048742 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle fiber development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." ;
rdfs:subClassOf obo:GO_0010830 , obo:GO_0060284 , obo:GO_0065007 .
obo:GO_0001570 a rdfs:Class ;
rdfs:label "vasculogenesis" ;
rdfs:comment "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0033505 a rdfs:Class ;
rdfs:label "floor plate morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the floor plate is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048598 , obo:GO_0048729 .
obo:GO_0032351 a rdfs:Class ;
rdfs:label "negative regulation of hormone metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0032350 , obo:GO_0065007 .
obo:GO_0009894 a rdfs:Class ;
rdfs:label "regulation of catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_0042648 a rdfs:Class ;
rdfs:label "chloroplast chromosome" ;
rdfs:comment "A circular DNA molecule containing chloroplast encoded genes." ;
rdfs:subClassOf obo:GO_0005694 , obo:GO_0009508 .
obo:GO_0005539 a rdfs:Class ;
rdfs:label "glycosaminoglycan binding" ;
rdfs:comment "Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0097367 .
obo:UBERON_0005401 a rdfs:Class ;
rdfs:label "cerebral hemisphere gray matter" ;
rdfs:comment "A gray matter that is part of a cerebral hemisphere." ;
rdfs:subClassOf obo:UBERON_0002020 , obo:UBERON_0011300 .
obo:PHIPO_0000597 a rdfs:Class ;
rdfs:label "resistance to polymyxin B1"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to polymyxin B1. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0000955 a rdfs:Class ;
rdfs:label "brain" ;
rdfs:comment "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0004121 .
obo:GO_0061853 a rdfs:Class ;
rdfs:label "regulation of neuroblast migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuroblast migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:CL_0002612 a rdfs:Class ;
rdfs:label "neuron of the ventral spinal cord" ;
rdfs:comment "A neuron of the ventral spinal cord." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000029 .
obo:CHEBI_59062 a rdfs:Class ;
rdfs:label "polymyxin" ;
rdfs:comment "Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria." ;
rdfs:subClassOf obo:CHEBI_24533 , obo:CHEBI_46895 .
obo:GO_0072593 a rdfs:Class ;
rdfs:label "reactive oxygen species metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." ;
rdfs:subClassOf obo:GO_0008152 .
obo:CL_0000129 a rdfs:Class ;
rdfs:label "microglial cell" ;
rdfs:comment "A transcriptomically distinct central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive." ;
rdfs:subClassOf obo:CL_0000125 , obo:CL_0000878 .
obo:GO_0032232 a rdfs:Class ;
rdfs:label "negative regulation of actin filament bundle assembly" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles." ;
rdfs:subClassOf obo:GO_0032231 , obo:GO_0051494 , obo:GO_0065007 , obo:GO_1902904 .
obo:GO_0008233 a rdfs:Class ;
rdfs:label "peptidase activity" ;
rdfs:comment "Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid." ;
rdfs:subClassOf obo:GO_0016787 , obo:GO_0140096 .
obo:GO_2001019 a rdfs:Class ;
rdfs:label "positive regulation of retrograde axon cargo transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0065007 , obo:GO_2001017 .
obo:GO_0140253 a rdfs:Class ;
rdfs:label "cell-cell fusion" ;
rdfs:comment "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0160093 a rdfs:Class ;
rdfs:label "chordate pharynx development" ;
rdfs:comment "The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060465 .
obo:UBERON_0006284 a rdfs:Class ;
rdfs:label "early prosencephalic vesicle" ;
rdfs:comment "Future brain vesicle that gives rise to telencephalic ventricle/lateral ventricles and 3rd ventricle." ;
rdfs:subClassOf obo:UBERON_0013150 .
obo:CHEBI_29258 a rdfs:Class ;
rdfs:label "dihydrogenphosphite" ;
rdfs:comment "A monovalent inorganic anion obtained by deprotonation of phosphorous acid." ;
rdfs:subClassOf obo:CHEBI_26045 , obo:CHEBI_79389 .
obo:CHEBI_5385 a rdfs:Class ;
rdfs:label "gliotoxin" ;
rdfs:comment "A pyrazinoindole with a disulfide bridge spanning a dioxo-substituted pyrazine ring; mycotoxin produced by several species of fungi." ;
rdfs:subClassOf obo:CHEBI_35489 , obo:CHEBI_38163 , obo:CHEBI_46761 , obo:CHEBI_64130 .
obo:PHIPO_0001257 a rdfs:Class ;
rdfs:label "decreased level of host defense-induced protein"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host protein usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001262 .
obo:UBERON_0001775 a rdfs:Class ;
rdfs:label "ciliary body" ;
rdfs:comment "The thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0004121 , obo:UBERON_0010314 .
obo:UBERON_0008851 a rdfs:Class ;
rdfs:label "ectoplacental cavity" ;
rdfs:comment "Closed space within the ectoplacental cone, formed by the fusion of the parts of the amniotic fold that separate it from the amniotic cavity[MP]. a developmental cavity that exists in some mammals and is derived by division of the proamniotic space; it is further removed from the embryo than the amniotic cavity in some mammals." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0016049 a rdfs:Class ;
rdfs:label "cell growth" ;
rdfs:comment "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0040007 .
obo:PHIPO_0001221 a rdfs:Class ;
rdfs:label "abnormal anatomical structure physical quality phenotype"@en ;
rdfs:comment "A physical anatomical structure phenotype in which the amount, distribution, morphology, or other physical characteristic of a cell part, cell, or tissue, or individual is abnormal in the vegetative growth phase of the life cycle." ;
rdfs:subClassOf obo:PHIPO_0001373 .
obo:GO_0019747 a rdfs:Class ;
rdfs:label "regulation of isoprenoid metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids." ;
rdfs:subClassOf obo:GO_0019216 , obo:GO_0065007 .
obo:GO_0009526 a rdfs:Class ;
rdfs:label "plastid envelope" ;
rdfs:comment "The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space." ;
rdfs:subClassOf obo:GO_0031967 .
obo:PHIPO_0000615 a rdfs:Class ;
rdfs:label "resistance to D-cycloserine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to D-cycloserine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0023061 a rdfs:Class ;
rdfs:label "signal release" ;
rdfs:comment "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." ;
rdfs:subClassOf obo:GO_0032940 .
obo:UBERON_0010131 a rdfs:Class ;
rdfs:label "conducting tissue of heart" ;
rdfs:comment "Any portion of cardiac muscle tissue that is part of the conducting system of heart or the Purkinje fibers." ;
rdfs:subClassOf obo:UBERON_0001133 .
obo:PHIPO_0000133 a rdfs:Class ;
rdfs:label "abnormal protein-protein interaction"@en ;
rdfs:comment "A single species molecular function phenotype in which the binding of one protein to another is abnormal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000132 , obo:PHIPO_0000413 .
obo:CHEBI_22723 a rdfs:Class ;
rdfs:label "benzoic acids" ;
rdfs:comment "Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_33859 .
obo:CL_0000738 a rdfs:Class ;
rdfs:label "leukocyte" ;
rdfs:comment "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ;
rdfs:subClassOf obo:CL_0000219 , obo:CL_0000255 , obo:CL_0000988 , obo:CL_0002242 .
obo:PATO_0045010 a rdfs:Class ;
rdfs:label "normal concentration" ;
rdfs:comment "A concentration which is relatively normal or average." ;
rdfs:subClassOf obo:PATO_0001159 , obo:PATO_0045001 .
obo:GO_0060251 a rdfs:Class ;
rdfs:label "regulation of glial cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glial cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:PR_000001020 a rdfs:Class ;
rdfs:label "CD3 epsilon" ;
rdfs:comment "A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001018 .
obo:GO_0090170 a rdfs:Class ;
rdfs:label "regulation of Golgi inheritance" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903358 .
obo:CHEBI_36988 a rdfs:Class ;
rdfs:label "5'-deoxyribonucleoside" ;
rdfs:subClassOf obo:CHEBI_23636 .
obo:GO_0060541 a rdfs:Class ;
rdfs:label "respiratory system development" ;
rdfs:comment "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:UBERON_0004699 a rdfs:Class ;
rdfs:label "outflow tract endothelium" ;
rdfs:comment "An endothelium that is part of a outflow tract [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0008307 .
obo:CHEBI_32867 a rdfs:Class ;
rdfs:label "D-prolinate" ;
rdfs:comment "An optically active form of prolinate having D-configuration." ;
rdfs:subClassOf obo:CHEBI_32871 .
obo:CHEBI_33666 a rdfs:Class ;
rdfs:label "polycyclic hydrocarbon" ;
rdfs:subClassOf obo:CHEBI_33663 , obo:CHEBI_35294 .
obo:UBERON_0000118 a rdfs:Class ;
rdfs:label "lung bud" ;
rdfs:comment "Structure derived from foregut that becomes a lung[GO]." ;
rdfs:subClassOf obo:UBERON_0005153 .
obo:GO_0140375 a rdfs:Class ;
rdfs:label "immune receptor activity" ;
rdfs:comment "Receiving a signal and transmitting it in a cell to initiate an immune response." ;
rdfs:subClassOf obo:GO_0038023 .
obo:UBERON_0005664 a rdfs:Class ;
rdfs:label "2nd arch endoderm" ;
rdfs:comment "An endoderm that is part of a pharyngeal arch 2." ;
rdfs:subClassOf obo:UBERON_0000925 .
obo:CL_4307039 a rdfs:Class ;
rdfs:label "Astro-TE NN_1 Rasl10b astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Ddn (Mmus), Myoc (Mmus), Rasl10b (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Rasl10b, Igfbp5. These cells are located in the Hippocampal region, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5219 Astro-TE NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301591 .
obo:GO_1905953 a rdfs:Class ;
rdfs:label "negative regulation of lipid localization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0065007 , obo:GO_1905952 .
obo:UBERON_0003586 a rdfs:Class ;
rdfs:label "trunk connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:GO_0002617 a rdfs:Class ;
rdfs:label "negative regulation of macrophage antigen processing and presentation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002578 , obo:GO_0002616 , obo:GO_0065007 .
obo:CHEBI_167559 a rdfs:Class ;
rdfs:label "glycan" ;
rdfs:comment "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." ;
rdfs:subClassOf obo:CHEBI_78616 .
obo:GO_0051253 a rdfs:Class ;
rdfs:label "negative regulation of RNA metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." ;
rdfs:subClassOf obo:GO_0010605 , obo:GO_0045934 , obo:GO_0051252 , obo:GO_0065007 .
obo:GO_0070124 a rdfs:Class ;
rdfs:label "mitochondrial translational initiation" ;
rdfs:comment "The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA." ;
rdfs:subClassOf obo:GO_0006413 .
obo:CHEBI_35552 a rdfs:Class ;
rdfs:label "heterocyclic organic fundamental parent" ;
rdfs:subClassOf obo:CHEBI_33245 .
obo:CHEBI_46081 a rdfs:Class ;
rdfs:label "fluconazole" ;
rdfs:comment "A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis." ;
rdfs:subClassOf obo:CHEBI_26878 , obo:CHEBI_38582 , obo:CHEBI_87071 , obo:CHEBI_87101 .
obo:PHIPO_0000336 a rdfs:Class ;
rdfs:label "obsolete intracellular growth phenotype" .
obo:GO_0010711 a rdfs:Class ;
rdfs:label "negative regulation of collagen catabolic process" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0010710 , obo:GO_0010713 , obo:GO_0065007 .
obo:CHEBI_38313 a rdfs:Class ;
rdfs:label "diazines" ;
rdfs:comment "Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure)." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:GO_0045646 a rdfs:Class ;
rdfs:label "regulation of erythrocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of erythrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045637 , obo:GO_0065007 .
obo:GO_0002468 a rdfs:Class ;
rdfs:label "dendritic cell antigen processing and presentation" ;
rdfs:comment "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." ;
rdfs:subClassOf obo:GO_0019882 .
obo:CHEBI_35942 a rdfs:Class ;
rdfs:label "neurotransmitter agent" ;
rdfs:comment "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_52210 .
obo:GO_0010595 a rdfs:Class ;
rdfs:label "positive regulation of endothelial cell migration" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." ;
rdfs:subClassOf obo:GO_0010594 , obo:GO_0030335 , obo:GO_0065007 .
obo:GO_0032530 a rdfs:Class ;
rdfs:label "regulation of microvillus organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120035 .
obo:GO_0021556 a rdfs:Class ;
rdfs:label "central nervous system formation" ;
rdfs:comment "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CL_0002465 a rdfs:Class ;
rdfs:label "CD11b-positive dendritic cell" ;
rdfs:comment "A conventional dendritic cell that expresses CD11b (ITGAM)." ;
rdfs:subClassOf obo:CL_0000990 .
obo:CHEBI_47857 a rdfs:Class ;
rdfs:label "ureas" ;
rdfs:subClassOf obo:CHEBI_33256 .
obo:CHEBI_50860 a rdfs:Class ;
rdfs:label "organic molecular entity" ;
rdfs:comment "Any molecular entity that contains carbon." ;
rdfs:subClassOf obo:CHEBI_33582 .
obo:GO_0110057 a rdfs:Class ;
rdfs:label "regulation of blood vessel endothelial cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation." ;
rdfs:subClassOf obo:GO_0045601 , obo:GO_0065007 .
obo:GO_0021587 a rdfs:Class ;
rdfs:label "cerebellum morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CL_0011111 a rdfs:Class ;
rdfs:label "hypothalamic gonadotropin-releasing hormone neuron" ;
rdfs:comment "a specialized neuroendocrine cell that synthesizes and secretes GnRH decapeptide, a key regulator of reproductive function. It originates from the olfactory placode during embryonic development and migrates into the forebrain where it localises predominantly in the hypothalamus and in humans, in extrahypothalamic regions like the basal ganglia (Skrapits et al., 2021). This cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation. It expresses receptor subunits required for AMPA, NMDA, and kainate receptor signaling and may use glutamate as a neurotransmitter in recurrent collateral innervation." ;
rdfs:subClassOf obo:CL_0000165 , obo:CL_0012001 .
obo:RO_0002596 a rdf:Property ;
rdfs:label "capable of regulating" ;
rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a regulates p." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002500 .
obo:GO_0099123 a rdfs:Class ;
rdfs:label "somato-dendritic dopamine secretion" ;
rdfs:comment "The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron." ;
rdfs:subClassOf obo:GO_0014046 , obo:GO_0051649 .
obo:PHIPO_0000463 a rdfs:Class ;
rdfs:label "subcellular component phenotype"@en ;
rdfs:comment "A single organism phenotype that affects the subcellular components in a cell." ;
rdfs:subClassOf obo:PHIPO_0000034 .
obo:GO_0001941 a rdfs:Class ;
rdfs:label "postsynaptic membrane organization" ;
rdfs:comment "A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft)." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0061024 .
obo:CL_1001603 a rdfs:Class ;
rdfs:label "lung macrophage" ;
rdfs:comment "Circulating macrophages and tissue macrophages (alveolar macrophages) of lung." ;
rdfs:subClassOf obo:CL_0000235 .
obo:GO_0007135 a rdfs:Class ;
rdfs:label "meiosis II" ;
rdfs:comment "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II." ;
rdfs:subClassOf obo:GO_0061983 , obo:GO_0140013 .
obo:PHIPO_0001451 a rdfs:Class ;
rdfs:label "sensitive to acidity"@en ;
rdfs:comment "A cell phenotype in which cells grow to a lower extent than wild type following exposure to acidic pH." ;
rdfs:subClassOf obo:PHIPO_0001098 .
obo:GO_0003353 a rdfs:Class ;
rdfs:label "positive regulation of cilium movement" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." ;
rdfs:subClassOf obo:GO_0003352 , obo:GO_0048522 , obo:GO_0065007 .
obo:GO_0003723 a rdfs:Class ;
rdfs:label "RNA binding" ;
rdfs:comment "Binding to an RNA molecule or a portion thereof." ;
rdfs:subClassOf obo:GO_0003676 , obo:GO_0005488 .
obo:GO_0022037 a rdfs:Class ;
rdfs:label "metencephalon development" ;
rdfs:comment "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0012467 a rdfs:Class ;
rdfs:label "enclosed anatomical space" ;
rdfs:comment "An anatomical space with no opening to another space or to the exterior." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_1904690 a rdfs:Class ;
rdfs:label "positive regulation of cytoplasmic translational initiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation." ;
rdfs:subClassOf obo:GO_0045948 , obo:GO_0065007 , obo:GO_1904688 .
obo:CHEBI_87069 a rdfs:Class ;
rdfs:label "imidazole antifungal drug" ;
rdfs:comment "Any imidazole antifungal agent that has been used for the treatment of fungal infections in humans or animals." ;
rdfs:subClassOf obo:CHEBI_86420 .
obo:PHIPO_0001106 a rdfs:Class ;
rdfs:label "presence of pathogen host protein-protein interaction"@en ;
rdfs:comment "A molecular function phenotype in which the binding of one pathogen protein to one host protein is present." ;
rdfs:subClassOf obo:PHIPO_0000131 .
obo:PHIPO_0000481 a rdfs:Class ;
rdfs:label "absence of pathogen-associated host lesions"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion is absent." ;
rdfs:subClassOf obo:PHIPO_0000445 .
obo:PHIPO_0000600 a rdfs:Class ;
rdfs:label "resistance to capreomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to capreomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0009607 a rdfs:Class ;
rdfs:label "response to biotic stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." ;
rdfs:subClassOf obo:GO_0050896 .
obo:GO_0042308 a rdfs:Class ;
rdfs:label "negative regulation of protein import into nucleus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus." ;
rdfs:subClassOf obo:GO_0042306 , obo:GO_0046823 , obo:GO_0065007 , obo:GO_0090317 , obo:GO_1900181 .
obo:PHIPO_0000586 a rdfs:Class ;
rdfs:label "resistance to anidulafungin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to anidulafungin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0099641 a rdfs:Class ;
rdfs:label "anterograde axonal protein transport" ;
rdfs:comment "The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0008089 , obo:GO_0099640 , obo:GO_1905383 .
obo:UBERON_0019189 a rdfs:Class ;
rdfs:label "carotid artery endothelium" ;
rdfs:subClassOf obo:UBERON_0001917 , obo:UBERON_0001986 .
obo:CHEBI_26079 a rdfs:Class ;
rdfs:label "phosphoric acid derivative" ;
rdfs:subClassOf obo:CHEBI_36359 .
obo:PATO_0000499 a rdfs:Class ;
rdfs:label "decreased duration" ;
rdfs:comment "A duration quality of a process which is relatively low." ;
rdfs:subClassOf obo:PATO_0001309 , obo:PATO_0002302 .
obo:GO_0008585 a rdfs:Class ;
rdfs:label "female gonad development" ;
rdfs:comment "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0008406 , obo:GO_0048856 .
obo:GO_0015671 a rdfs:Class ;
rdfs:label "oxygen transport" ;
rdfs:comment "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015669 .
obo:PHIPO_0000833 a rdfs:Class ;
rdfs:label "sensitive to imipenem"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to imipenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000819 .
obo:GO_0009966 a rdfs:Class ;
rdfs:label "regulation of signal transduction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of signal transduction." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0023051 , obo:GO_0048583 , obo:GO_0065007 .
obo:GO_0009620 a rdfs:Class ;
rdfs:label "response to fungus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_0051707 .
obo:GO_0021538 a rdfs:Class ;
rdfs:label "epithalamus development" ;
rdfs:comment "The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle." ;
rdfs:subClassOf obo:GO_0048856 .
obo:PHIPO_0001140 a rdfs:Class ;
rdfs:label "host PAMP-triggered immunity signaling activated by pathogen present"@en ;
rdfs:comment "A cell signaling pathway phenotype where the host pattern recognition receptor signaling pathway is directly induced by a pathogen. This can include any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to a pathogen-derived physiological ligand. PRR ligands are usually referred to as pathogen-associated molecular pattern (PAMPs) or microbe-associated molecular pattern (MAMPs), structures conserved among microbial species (GO:0002221)." ;
rdfs:subClassOf obo:PHIPO_0001117 , obo:PHIPO_0001246 .
obo:UBERON_0005068 a rdfs:Class ;
rdfs:label "neural rod" ;
rdfs:comment "A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]." ;
rdfs:subClassOf obo:UBERON_0016879 .
obo:CHEBI_37533 a rdfs:Class ;
rdfs:label "azo compound" ;
rdfs:comment "Derivatives of diazene with the general structure R‒N=N‒R'." ;
rdfs:subClassOf obo:CHEBI_51143 .
obo:PHIPO_0000734 a rdfs:Class ;
rdfs:label "sensitive to plumbagin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to plumbagin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0008188 a rdfs:Class ;
rdfs:label "neuropeptide receptor activity" ;
rdfs:comment "Combining with a neuropeptide to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0008528 .
obo:PHIPO_0000873 a rdfs:Class ;
rdfs:label "sensitive to rapamycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to rapamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0009666 a rdfs:Class ;
rdfs:label "plastid outer membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid." ;
rdfs:subClassOf obo:GO_0009668 , obo:GO_0016043 .
obo:GO_0050832 a rdfs:Class ;
rdfs:label "defense response to fungus" ;
rdfs:comment "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." ;
rdfs:subClassOf obo:GO_0006952 , obo:GO_0009620 .
obo:UBERON_0009494 a rdfs:Class ;
rdfs:label "pharyngeal arch mesenchymal region" ;
rdfs:comment "A portion of mesenchymal tissue associated with an individual pharyngeal arch." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005291 , obo:UBERON_0007524 .
obo:GO_0002613 a rdfs:Class ;
rdfs:label "regulation of monocyte antigen processing and presentation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002577 , obo:GO_0065007 .
obo:GO_0043069 a rdfs:Class ;
rdfs:label "negative regulation of programmed cell death" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0048523 , obo:GO_0065007 .
obo:GO_0003283 a rdfs:Class ;
rdfs:label "atrial septum development" ;
rdfs:comment "The progression of the atrial septum over time, from its initial formation to the mature structure." ;
rdfs:subClassOf obo:GO_0003279 , obo:GO_0048856 .
obo:PHIPO_0000795 a rdfs:Class ;
rdfs:label "sensitive to carbenicillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to carbenicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:GO_0052372 a rdfs:Class ;
rdfs:label "modulation by symbiont of entry into host" ;
rdfs:comment "Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0043903 , obo:GO_0065007 .
obo:CHEBI_49201 a rdfs:Class ;
rdfs:label "anti-ulcer drug" ;
rdfs:comment "One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0021567 a rdfs:Class ;
rdfs:label "rhombomere 1 development" ;
rdfs:comment "The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." ;
rdfs:subClassOf obo:GO_0021546 , obo:GO_0048856 .
obo:UBERON_0004830 a rdfs:Class ;
rdfs:label "respiratory system skeletal muscle" ;
rdfs:comment "A portion of skeletal muscle tissue that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001134 .
obo:UBERON_0004688 a rdfs:Class ;
rdfs:label "costo-cervical trunk" ;
rdfs:comment "The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:CHEBI_48132 a rdfs:Class ;
rdfs:label "tetracenomycin" ;
rdfs:comment "A polyketide based on a tetracene ring structure." ;
rdfs:subClassOf obo:CHEBI_26188 .
obo:PHIPO_0001274 a rdfs:Class ;
rdfs:label "host immune system phagocytosis of pathogen present"@en ;
rdfs:comment "A pathogen host interaction phenotype where the host immune system activates the phagocytosis of a pathogen (GO:0006911)." ;
rdfs:subClassOf obo:PHIPO_0001167 .
obo:GO_0032102 a rdfs:Class ;
rdfs:label "negative regulation of response to external stimulus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." ;
rdfs:subClassOf obo:GO_0032101 , obo:GO_0048585 , obo:GO_0065007 .
obo:PATO_0001178 a rdfs:Class ;
rdfs:label "resistant to" ;
rdfs:comment "A resistance quality inhering in a bearer by virtue of the bearer's resistance to a stimulus." ;
rdfs:subClassOf obo:PATO_0001046 .
obo:CHEBI_26455 a rdfs:Class ;
rdfs:label "pyrroles" ;
rdfs:comment "An azole that includes only one N atom and no other heteroatom as a part of the aromatic skeleton." ;
rdfs:subClassOf obo:CHEBI_68452 .
obo:CL_4307105 a rdfs:Class ;
rdfs:label "MOL NN_4 Spock3 mature myelinating oligodendrocyte (Mmus)" ;
rdfs:comment "A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), A230001M10Rik (Mmus), Spock3 (Mmus), Rhoj (Mmus). It is distinguished from other MOL NN_4 cells by expression of Spock3, Rhoj. These cells are located in the Midbrain, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5285 MOL NN_4." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301614 .
obo:UBERON_0002099 a rdfs:Class ;
rdfs:label "cardiac septum" ;
rdfs:comment "The thin membranous structure between parts of the heart, including the atria, ventricles, and outflow tract." ;
rdfs:subClassOf obo:UBERON_0003037 .
obo:GO_0043229 a rdfs:Class ;
rdfs:label "intracellular organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0043226 .
obo:GO_0051017 a rdfs:Class ;
rdfs:label "actin filament bundle assembly" ;
rdfs:comment "The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0061572 .
obo:GO_0098871 a rdfs:Class ;
rdfs:label "postsynaptic actin cytoskeleton" ;
rdfs:comment "The actin cytoskeleton that is part of a postsynapse." ;
rdfs:subClassOf obo:GO_0015629 , obo:GO_0099571 .
obo:UBERON_0001800 a rdfs:Class ;
rdfs:label "sensory ganglion" ;
rdfs:comment "The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells." ;
rdfs:subClassOf obo:UBERON_0000045 .
obo:GO_0043462 a rdfs:Class ;
rdfs:label "regulation of ATP-dependent activity" ;
rdfs:comment "Any process that modulates the rate of an ATP-dependent activity." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:PHIPO_0000975 a rdfs:Class ;
rdfs:label "increased unicellular population growth"@en ;
rdfs:comment "A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is greater than normal." ;
rdfs:subClassOf obo:PHIPO_0000414 , obo:PHIPO_0000929 .
obo:GO_0101023 a rdfs:Class ;
rdfs:label "vascular endothelial cell proliferation" ;
rdfs:comment "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population." ;
rdfs:subClassOf obo:GO_0001935 , obo:GO_0008283 .
obo:GO_0031272 a rdfs:Class ;
rdfs:label "regulation of pseudopodium assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the assembly of pseudopodia." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120032 .
obo:GO_0050994 a rdfs:Class ;
rdfs:label "regulation of lipid catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0019216 , obo:GO_0065007 .
obo:GO_0043269 a rdfs:Class ;
rdfs:label "regulation of monoatomic ion transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:UBERON_0005622 a rdfs:Class ;
rdfs:label "right dorsal aorta" ;
rdfs:subClassOf obo:UBERON_0000947 , obo:UBERON_0003513 .
obo:GO_0033045 a rdfs:Class ;
rdfs:label "regulation of sister chromatid segregation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of sister chromatid segregation." ;
rdfs:subClassOf obo:GO_0033044 , obo:GO_0051983 , obo:GO_0065007 .
obo:PHIPO_0001048 a rdfs:Class ;
rdfs:label "obsolete normal level of substance phenotype in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is normal (i.e. indistinguishable from wild type)." .
obo:GO_1905433 a rdfs:Class ;
rdfs:label "negative regulation of retrograde trans-synaptic signaling by neuropeptide" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." ;
rdfs:subClassOf obo:GO_0010648 , obo:GO_0023057 , obo:GO_0065007 , obo:GO_1905432 .
obo:GO_1905288 a rdfs:Class ;
rdfs:label "vascular associated smooth muscle cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a vascular associated smooth muscle cell." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0034390 .
obo:GO_0043296 a rdfs:Class ;
rdfs:label "apical junction complex" ;
rdfs:comment "A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability." ;
rdfs:subClassOf obo:GO_0005911 .
obo:CHEBI_17418 a rdfs:Class ;
rdfs:label "valeric acid" ;
rdfs:comment "A straight-chain saturated fatty acid containing five carbon atoms." ;
rdfs:subClassOf obo:CHEBI_26666 , obo:CHEBI_39418 .
obo:CL_0000076 a rdfs:Class ;
rdfs:label "squamous epithelial cell" ;
rdfs:comment "An epithelial cell that has a flattened morphology." ;
rdfs:subClassOf obo:CL_0000066 .
obo:GO_0048519 a rdfs:Class ;
rdfs:label "negative regulation of biological process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:NCBITaxon_33317 a rdfs:Class ;
rdfs:label "Protostomia" ;
rdfs:subClassOf obo:NCBITaxon_33213 .
obo:PHIPO_0001217 a rdfs:Class ;
rdfs:label "stress phenotype"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity, resistance or absence of change of individuals or populations after exposure to a specific stress." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:PHIPO_0000838 a rdfs:Class ;
rdfs:label "sensitive to diniconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to diniconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0006694 a rdfs:Class ;
rdfs:label "cerebellum vasculature" ;
rdfs:comment "A vasculature that is part of a cerebellum." ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0006876 , obo:UBERON_0036303 .
obo:PHIPO_0000403 a rdfs:Class ;
rdfs:label "normal cell phenotype"@en ;
rdfs:comment "A phenotype that does not show any detectable differences from normal at the level of an individual cell." ;
rdfs:subClassOf obo:PHIPO_0000034 .
obo:UBERON_0007688 a rdfs:Class ;
rdfs:label "anlage" ;
rdfs:comment "Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue." ;
rdfs:subClassOf obo:UBERON_0000479 , obo:UBERON_0005423 .
obo:CL_0000547 a rdfs:Class ;
rdfs:label "proerythroblast" ;
rdfs:comment "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." ;
rdfs:subClassOf obo:CL_0000764 , obo:CL_0002242 .
obo:GO_0097164 a rdfs:Class ;
rdfs:label "ammonium ion metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving the ammonium ion." ;
rdfs:subClassOf obo:GO_0008152 .
obo:CHEBI_50315 a rdfs:Class ;
rdfs:label "chloronium" ;
rdfs:subClassOf obo:CHEBI_50313 .
obo:GO_0061535 a rdfs:Class ;
rdfs:label "glutamate secretion, neurotransmission" ;
rdfs:comment "The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0007269 , obo:GO_0014047 , obo:GO_0051938 .
obo:UBERON_0002290 a rdfs:Class ;
rdfs:label "choroid plexus of fourth ventricle" ;
rdfs:comment "Choroid plexus of the fourth ventricle." ;
rdfs:subClassOf obo:UBERON_0001886 , obo:UBERON_0006694 .
obo:GO_0060761 a rdfs:Class ;
rdfs:label "negative regulation of response to cytokine stimulus" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus." ;
rdfs:subClassOf obo:GO_0048585 , obo:GO_0060759 , obo:GO_0065007 .
obo:GO_0051450 a rdfs:Class ;
rdfs:label "myoblast proliferation" ;
rdfs:comment "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ;
rdfs:subClassOf obo:GO_0008283 .
obo:CL_4310132 a rdfs:Class ;
rdfs:label "STRd D2 Matrix MSN matrix D2 medium spiny neuron (Primate)" ;
rdfs:comment "A matrix D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 Matrix MSN." ;
rdfs:subClassOf obo:CL_4030047 , obo:CL_4310059 .
obo:PHIPO_0000197 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host protein protein interaction" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which the binding of one protein to another is abnormal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." .
obo:CHEBI_25154 a rdfs:Class ;
rdfs:label "manganese molecular entity" ;
rdfs:subClassOf obo:CHEBI_33743 .
obo:GO_0031966 a rdfs:Class ;
rdfs:label "mitochondrial membrane" ;
rdfs:comment "Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031090 .
obo:CHEBI_28694 a rdfs:Class ;
rdfs:label "copper atom" ;
rdfs:subClassOf obo:CHEBI_33366 , obo:CHEBI_88184 .
obo:GO_0043476 a rdfs:Class ;
rdfs:label "pigment accumulation" ;
rdfs:comment "The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus." ;
rdfs:subClassOf obo:GO_0009605 , obo:GO_0043473 .
obo:GO_0003241 a rdfs:Class ;
rdfs:label "growth involved in heart morphogenesis" ;
rdfs:comment "Developmental growth that contributes to the shaping of the heart." ;
rdfs:subClassOf obo:GO_0040007 , obo:GO_0060560 .
obo:GO_0033684 a rdfs:Class ;
rdfs:label "regulation of luteinizing hormone secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone." ;
rdfs:subClassOf obo:GO_0032276 , obo:GO_0065007 .
obo:GO_0051781 a rdfs:Class ;
rdfs:label "positive regulation of cell division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell division." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0051302 , obo:GO_0065007 .
obo:GO_0097176 a rdfs:Class ;
rdfs:label "epoxide metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0033602 a rdfs:Class ;
rdfs:label "negative regulation of dopamine secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine." ;
rdfs:subClassOf obo:GO_0014059 , obo:GO_0033604 , obo:GO_0065007 .
obo:PHIPO_0000375 a rdfs:Class ;
rdfs:label "delayed timing of pathogen penetration structure formation when near host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the formation of pathogen specialized penetration structure begins later than normal." ;
rdfs:subClassOf obo:PHIPO_0000369 .
obo:GO_0044085 a rdfs:Class ;
rdfs:label "cellular component biogenesis" ;
rdfs:comment "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." ;
rdfs:subClassOf obo:GO_0071840 .
obo:GO_0099551 a rdfs:Class ;
rdfs:label "trans-synaptic signaling by neuropeptide, modulating synaptic transmission" ;
rdfs:comment "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse." ;
rdfs:subClassOf obo:GO_0099537 , obo:GO_0099540 , obo:GO_0099550 .
obo:GO_1901031 a rdfs:Class ;
rdfs:label "regulation of response to reactive oxygen species" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of response to reactive oxygen species." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902882 .
obo:PHIPO_0000161 a rdfs:Class ;
rdfs:label "reproductive phenotype"@en ;
rdfs:comment "A single species phenotype which affects the reproductive process. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003)." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:PHIPO_0001401 a rdfs:Class ;
rdfs:label "normal growth on flusilazole" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to flusilazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0000740 a rdfs:Class ;
rdfs:label "nuclear membrane fusion" ;
rdfs:comment "The joining of 2 or more lipid bilayer membranes that surround the nucleus." ;
rdfs:subClassOf obo:GO_0061025 , obo:GO_0071763 , obo:GO_0090174 .
obo:UBERON_0039856 a rdfs:Class ;
rdfs:label "right ovarian vein" ;
rdfs:comment "Ovarian vein, each instance of which is a tributary of some inferior vena cava that drains the right pampiniform plexus of some broad ligament." ;
rdfs:subClassOf obo:UBERON_0001145 .
obo:RO_0002376 a rdf:Property ;
rdfs:label "tributary of"@en ;
rdfs:comment "x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002375 , obo:RO_0002170 .
obo:UBERON_0003089 a rdfs:Class ;
rdfs:label "sclerotome" ;
rdfs:comment "Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]." ;
rdfs:subClassOf obo:UBERON_0005856 , obo:UBERON_0007530 .
obo:GO_0008544 a rdfs:Class ;
rdfs:label "epidermis development" ;
rdfs:comment "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." ;
rdfs:subClassOf obo:GO_0009888 .
obo:PHIPO_0000209 a rdfs:Class ;
rdfs:label "obsolete increased stature" .
obo:PHIPO_0001393 a rdfs:Class ;
rdfs:label "normal growth on metconazole" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to metconazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CL_0000183 a rdfs:Class ;
rdfs:label "contractile cell" ;
rdfs:comment "A cell whose primary function is to shorten." ;
rdfs:subClassOf obo:CL_0000000 .
obo:UBERON_0002202 a rdfs:Class ;
rdfs:label "submucosa of trachea" ;
rdfs:comment "A submucosa that is part of a trachea." ;
rdfs:subClassOf obo:UBERON_0000009 , obo:UBERON_0004777 .
obo:CHEBI_68481 a rdfs:Class ;
rdfs:label "mTOR inhibitor" ;
rdfs:comment "A protein kinase inhibitor of the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer." ;
rdfs:subClassOf obo:CHEBI_37699 .
obo:UBERON_0003118 a rdfs:Class ;
rdfs:label "pharyngeal arch artery 1" ;
rdfs:comment "The vessels formed within the first pair of branchial arches in embryogenesis." ;
rdfs:subClassOf obo:UBERON_0004363 .
obo:CHEBI_26820 a rdfs:Class ;
rdfs:label "sulfates" ;
rdfs:comment "Salts and esters of sulfuric acid" ;
rdfs:subClassOf obo:CHEBI_37826 .
obo:CL_4307087 a rdfs:Class ;
rdfs:label "OPC NN_1 Irx2 oligodendrocyte precursor cell (Mmus)" ;
rdfs:comment "A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Pclaf (Mmus), Irx2 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Neil3, Irx2. These cells are located in the Cerebellum, brain, Midbrain, Pons, Medulla . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5267 OPC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300366 .
obo:GO_0009566 a rdfs:Class ;
rdfs:label "fertilization" ;
rdfs:comment "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ;
rdfs:subClassOf obo:GO_0022414 .
obo:CHEBI_35470 a rdfs:Class ;
rdfs:label "central nervous system drug" ;
rdfs:comment "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:PHIPO_0001419 a rdfs:Class ;
rdfs:label "normal growth on penflufen" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to penflufen (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_1903541 a rdfs:Class ;
rdfs:label "regulation of exosomal secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of exosomal secretion." ;
rdfs:subClassOf obo:GO_0017157 , obo:GO_0065007 .
obo:PHIPO_0001180 a rdfs:Class ;
rdfs:label "absence of effector-independent host hypersensitive response"@en ;
rdfs:comment "A single species phenotype where the immune system process of host tissue hypersensitive response is absent in a pathogen effector-independant manner. (i.e. an alteration within the host does not activate the hypersensitive response in the absence of a pathogen)." ;
rdfs:subClassOf obo:PHIPO_0000446 .
obo:GO_0006952 a rdfs:Class ;
rdfs:label "defense response" ;
rdfs:comment "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." ;
rdfs:subClassOf obo:GO_0006950 .
obo:UBERON_0003438 a rdfs:Class ;
rdfs:label "iris nerve" ;
rdfs:comment "Any nerve that innervates the iris." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:CHEBI_40909 a rdfs:Class ;
rdfs:label "azoxystrobin" ;
rdfs:comment "An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture." ;
rdfs:subClassOf obo:CHEBI_18379 , obo:CHEBI_47985 , obo:CHEBI_48535 , obo:CHEBI_86484 .
obo:GO_0016031 a rdfs:Class ;
rdfs:label "tRNA import into mitochondrion" ;
rdfs:comment "The process in which a tRNA is transported from the cytosol into the mitochondrial matrix." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0035927 , obo:GO_0051031 .
obo:GO_0071674 a rdfs:Class ;
rdfs:label "mononuclear cell migration" ;
rdfs:comment "The movement of a mononuclear cell within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0050900 .
obo:CHEBI_38785 a rdfs:Class ;
rdfs:label "morpholines" ;
rdfs:comment "Any compound containing morpholine as part of its structure." ;
rdfs:subClassOf obo:CHEBI_46952 .
obo:GO_1904456 a rdfs:Class ;
rdfs:label "negative regulation of neuronal action potential" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential." ;
rdfs:subClassOf obo:GO_0045759 , obo:GO_0051970 , obo:GO_0065007 , obo:GO_0098908 .
obo:CL_4300101 a rdfs:Class ;
rdfs:label "STR D1 Gaba direct pathway medium spiny neuron (Mmus)" ;
rdfs:comment "A direct pathway medium spiny neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prkch (Mmus), Slc32a1 (Mmus), Drd1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:061 STR D1 Gaba." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4023026 .
obo:GO_0014063 a rdfs:Class ;
rdfs:label "negative regulation of serotonin secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin." ;
rdfs:subClassOf obo:GO_0014062 , obo:GO_0043271 , obo:GO_0065007 , obo:GO_1903531 .
obo:GO_0002701 a rdfs:Class ;
rdfs:label "negative regulation of production of molecular mediator of immune response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response." ;
rdfs:subClassOf obo:GO_0002698 , obo:GO_0002700 , obo:GO_0010629 , obo:GO_0065007 .
obo:GO_0060048 a rdfs:Class ;
rdfs:label "cardiac muscle contraction" ;
rdfs:comment "Muscle contraction of cardiac muscle tissue." ;
rdfs:subClassOf obo:GO_0006936 , obo:GO_0006941 .
obo:PHIPO_0000863 a rdfs:Class ;
rdfs:label "sensitive to camptothecin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to camptothecin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0061651 a rdfs:Class ;
rdfs:label "Atg12 conjugating enzyme activity" ;
rdfs:comment "Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue." ;
rdfs:subClassOf obo:GO_0019777 , obo:GO_0061650 .
obo:CHEBI_29281 a rdfs:Class ;
rdfs:label "alkyl sulfate" ;
rdfs:subClassOf obo:CHEBI_25704 , obo:CHEBI_26819 .
obo:UBERON_0001040 a rdfs:Class ;
rdfs:label "yolk sac" ;
rdfs:comment "A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]." ;
rdfs:subClassOf obo:UBERON_0005292 , obo:UBERON_0005631 , obo:UBERON_0007499 .
obo:NCBITaxon_1437010 a rdfs:Class ;
rdfs:label "Boreoeutheria" ;
rdfs:subClassOf obo:NCBITaxon_9347 .
obo:CHEBI_29537 a rdfs:Class ;
rdfs:label "avermectin B1b" ;
rdfs:subClassOf obo:CHEBI_50344 .
obo:GO_0051783 a rdfs:Class ;
rdfs:label "regulation of nuclear division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:UBERON_0010523 a rdfs:Class ;
rdfs:label "microcirculatory vessel" ;
rdfs:comment "A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses." ;
rdfs:subClassOf obo:UBERON_0000055 .
obo:GO_0150063 a rdfs:Class ;
rdfs:label "visual system development" ;
rdfs:comment "The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways." ;
rdfs:subClassOf obo:GO_0048880 .
obo:GO_0061138 a rdfs:Class ;
rdfs:label "morphogenesis of a branching epithelium" ;
rdfs:comment "The process in which the anatomical structures of a branched epithelium are generated and organized." ;
rdfs:subClassOf obo:GO_0001763 , obo:GO_0002009 .
obo:GO_0048520 a rdfs:Class ;
rdfs:label "positive regulation of behavior" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ;
rdfs:subClassOf obo:GO_0050795 , obo:GO_0051240 , obo:GO_0065007 .
obo:CHEBI_35275 a rdfs:Class ;
rdfs:label "S-glycosyl compound" ;
rdfs:comment "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and a S atom bound to a carbon atom, thus creating a C-S bond." ;
rdfs:subClassOf obo:CHEBI_59793 , obo:CHEBI_63161 , obo:CHEBI_73754 .
obo:CHEBI_75767 a rdfs:Class ;
rdfs:label "animal metabolite" ;
rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." ;
rdfs:subClassOf obo:CHEBI_75763 .
obo:GO_0060298 a rdfs:Class ;
rdfs:label "positive regulation of sarcomere organization" ;
rdfs:comment "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ;
rdfs:subClassOf obo:GO_0051155 , obo:GO_0051495 , obo:GO_0060297 , obo:GO_0065007 , obo:GO_1902905 .
obo:UBERON_0005669 a rdfs:Class ;
rdfs:label "peritoneal cavity mesothelium" ;
rdfs:comment "A mesothelium that is part of a peritoneal cavity." ;
rdfs:subClassOf obo:UBERON_0001136 .
obo:GO_0090276 a rdfs:Class ;
rdfs:label "regulation of peptide hormone secretion" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." ;
rdfs:subClassOf obo:GO_0002791 , obo:GO_0046883 , obo:GO_0065007 .
obo:CHEBI_64248 a rdfs:Class ;
rdfs:label "tunicamycin B1" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a pentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:CHEBI_50514 a rdfs:Class ;
rdfs:label "vasoconstrictor agent" ;
rdfs:comment "Drug used to cause constriction of the blood vessels." ;
rdfs:subClassOf obo:CHEBI_35554 .
obo:UBERON_0010091 a rdfs:Class ;
rdfs:label "future hindbrain meninx" ;
rdfs:comment "A multi-tissue structure that has the potential to develop into a meninx of hindbrain." ;
rdfs:subClassOf obo:UBERON_0005291 , obo:UBERON_0006598 , obo:UBERON_0007524 , obo:UBERON_0007645 .
obo:CL_0000115 a rdfs:Class ;
rdfs:label "endothelial cell" ;
rdfs:comment "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." ;
rdfs:subClassOf obo:CL_0000255 .
obo:CHEBI_28616 a rdfs:Class ;
rdfs:label "carbamic acid" ;
rdfs:comment "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_35605 , obo:CHEBI_64708 .
obo:GO_0003237 a rdfs:Class ;
rdfs:label "sinus venosus formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." ;
rdfs:subClassOf obo:GO_0003207 , obo:GO_0048646 .
obo:UBERON_0004777 a rdfs:Class ;
rdfs:label "respiratory system submucosa" ;
rdfs:comment "A submucosa that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000009 .
obo:PHIPO_0000783 a rdfs:Class ;
rdfs:label "sensitive to clarithromycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to clarithromycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_2571 a rdfs:Class ;
rdfs:label "aliphatic alcohol" ;
rdfs:comment "An alcohol derived from an aliphatic compound." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:GO_0098907 a rdfs:Class ;
rdfs:label "regulation of SA node cell action potential" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0050789 , obo:GO_0098901 .
obo:PHIPO_0000074 a rdfs:Class ;
rdfs:label "obsolete abnormal timing of sexual spore production" .
obo:GO_1904624 a rdfs:Class ;
rdfs:label "regulation of glycine secretion, neurotransmission" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission." ;
rdfs:subClassOf obo:GO_0032890 , obo:GO_0046928 , obo:GO_0051955 , obo:GO_0060092 , obo:GO_0065007 .
obo:GO_0120031 a rdfs:Class ;
rdfs:label "plasma membrane bounded cell projection assembly" ;
rdfs:comment "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0030031 , obo:GO_0120036 .
obo:CHEBI_53628 a rdfs:Class ;
rdfs:label "2,6-dideoxy-alpha-D-glucoside" ;
rdfs:comment "An α-D-glucoside deoxygenated at C-2 and C-6." ;
rdfs:subClassOf obo:CHEBI_22390 .
obo:GO_0000139 a rdfs:Class ;
rdfs:label "Golgi membrane" ;
rdfs:comment "The lipid bilayer surrounding any of the compartments of the Golgi apparatus." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0098588 .
obo:GO_1901623 a rdfs:Class ;
rdfs:label "regulation of lymphocyte chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0002688 , obo:GO_0065007 , obo:GO_2000401 .
obo:CHEBI_36359 a rdfs:Class ;
rdfs:label "phosphorus oxoacid derivative" ;
rdfs:subClassOf obo:CHEBI_33241 , obo:CHEBI_36360 .
obo:GO_0007166 a rdfs:Class ;
rdfs:label "cell surface receptor signaling pathway" ;
rdfs:comment "The series of molecular signals initiated by an extracellular ligand binding to a receptor located on the cell surface. The pathway ends with regulation of a downstream cellular process, e.g. transcription." ;
rdfs:subClassOf obo:GO_0007165 .
obo:GO_0003142 a rdfs:Class ;
rdfs:label "cardiogenic plate morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0010467 a rdfs:Class ;
rdfs:label "gene expression" ;
rdfs:comment "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes." ;
rdfs:subClassOf obo:GO_0009059 .
obo:CL_4310121 a rdfs:Class ;
rdfs:label "STR LYPD6-RSPO2 GABA GABAergic interneuron (Primate)" ;
rdfs:comment "A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR LYPD6-RSPO2 GABA." ;
rdfs:subClassOf obo:CL_0011005 .
obo:UBERON_0036286 a rdfs:Class ;
rdfs:label "wall of right ventricle" ;
rdfs:comment "Wall of ventricle which is continuous with the wall of pulmonary trunk." ;
rdfs:subClassOf obo:UBERON_0004784 .
obo:GO_1905833 a rdfs:Class ;
rdfs:label "negative regulation of microtubule nucleation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation." ;
rdfs:subClassOf obo:GO_0010968 , obo:GO_0031115 , obo:GO_0065007 .
obo:GO_0033696 a rdfs:Class ;
rdfs:label "heterochromatin boundary formation" ;
rdfs:comment "A process that forms a boundary that limits the spreading of heterochromatin along a chromosome." ;
rdfs:subClassOf obo:GO_0070828 .
obo:GO_0030335 a rdfs:Class ;
rdfs:label "positive regulation of cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 , obo:GO_2000147 .
obo:PHIPO_0000397 a rdfs:Class ;
rdfs:label "sensitive to iprodione"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to iprodione. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_36709 a rdfs:Class ;
rdfs:label "aminoquinoline" ;
rdfs:comment "Any member of the class of quinolines in which the quinoline skeleton is substituted by one or more amino or substituted-amino groups." ;
rdfs:subClassOf obo:CHEBI_26513 , obo:CHEBI_33860 .
obo:CL_4301593 a rdfs:Class ;
rdfs:label "Astro-TE NN_3 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Grin2c (Mmus), Dcc (Mmus), Slc7a10 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1163 Astro-TE NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300359 .
obo:PHIPO_0001037 a rdfs:Class ;
rdfs:label "increased cellular toxin level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of toxin measured in a cell is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001030 , obo:PHIPO_0001036 .
obo:GO_2001199 a rdfs:Class ;
rdfs:label "negative regulation of dendritic cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902106 , obo:GO_2001198 .
obo:GO_0009913 a rdfs:Class ;
rdfs:label "epidermal cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030855 .
obo:CHEBI_34995 a rdfs:Class ;
rdfs:label "teicoplanin A2-1" ;
rdfs:comment "A teicoplanin A2 that has (4Z)-dec-4-enoyl as the variable N-acyl group." ;
rdfs:subClassOf obo:CHEBI_34994 .
obo:CHEBI_15705 a rdfs:Class ;
rdfs:label "L-alpha-amino acid" ;
rdfs:comment "Any α-amino acid having L-configuration at the α-carbon." ;
rdfs:subClassOf obo:CHEBI_33704 .
obo:GO_0003677 a rdfs:Class ;
rdfs:label "DNA binding" ;
rdfs:comment "Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid)." ;
rdfs:subClassOf obo:GO_0003676 , obo:GO_0005488 .
obo:GO_0030279 a rdfs:Class ;
rdfs:label "negative regulation of ossification" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." ;
rdfs:subClassOf obo:GO_0030278 , obo:GO_0051241 , obo:GO_0065007 .
obo:UBERON_0005085 a rdfs:Class ;
rdfs:label "ectodermal placode" ;
rdfs:comment "An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO]." ;
rdfs:subClassOf obo:UBERON_0001048 , obo:UBERON_0002050 .
obo:BFO_0000040 a rdfs:Class ;
rdfs:label "material entity"@en ;
rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
rdfs:subClassOf obo:BFO_0000004 .
obo:UBERON_0005884 a rdfs:Class ;
rdfs:label "hyoid arch skeleton" ;
rdfs:comment "A subdivision of skeleton that supports pharyngeal arch 2." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:GO_0098764 a rdfs:Class ;
rdfs:label "meiosis I cell cycle phase" ;
rdfs:comment "A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs." ;
rdfs:subClassOf obo:GO_0098762 .
obo:RO_0002092 a rdf:Property ;
rdfs:label "happens during" ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002093 .
obo:CHEBI_3392 a rdfs:Class ;
rdfs:label "carbendazim" ;
rdfs:comment "A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables." ;
rdfs:subClassOf obo:CHEBI_87036 , obo:CHEBI_87064 .
obo:GO_0016787 a rdfs:Class ;
rdfs:label "hydrolase activity" ;
rdfs:comment "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc." ;
rdfs:subClassOf obo:GO_0003824 .
obo:CHEBI_35816 a rdfs:Class ;
rdfs:label "leprostatic drug" ;
rdfs:comment "A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions." ;
rdfs:subClassOf obo:CHEBI_64912 .
obo:GO_2000284 a rdfs:Class ;
rdfs:label "positive regulation of amino acid biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0045764 , obo:GO_0065007 , obo:GO_2000282 .
obo:GO_0071418 a rdfs:Class ;
rdfs:label "cellular response to amine stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." ;
rdfs:subClassOf obo:GO_0014075 , obo:GO_0070887 , obo:GO_1901699 .
obo:UBERON_0004375 a rdfs:Class ;
rdfs:label "bone of free limb or fin" ;
rdfs:comment "A bone that is part of an appendage [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0010740 .
obo:GO_0010566 a rdfs:Class ;
rdfs:label "regulation of ketone biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0010565 , obo:GO_0062012 , obo:GO_0065007 .
obo:UBERON_0001514 a rdfs:Class ;
rdfs:label "descending aorta" ;
rdfs:comment "The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries[GO]. The descending aorta is part of the aorta, the largest artery in the body. The descending aorta is the part of the aorta beginning at the aortic arch that runs down through the chest and abdomen. The descending aorta is divided into two portions, the thoracic and abdominal, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the legs. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0005800 .
obo:PATO_0001457 a rdfs:Class ;
rdfs:label "sensitivity of a process" ;
rdfs:comment "A quality of a process inhering in bearer by virtue of the bearer's disposition to respond to stimulation." ;
rdfs:subClassOf obo:PATO_0002062 .
obo:PHIPO_0001285 a rdfs:Class ;
rdfs:label "increased level of host defense-related RNA involved in a pathogen interaction"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host defense-related RNA usually present during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001104 .
obo:PHIPO_0000364 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen growth within host" ;
rdfs:comment "A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is abnormal (i.e different than wild type)." .
obo:GO_0060419 a rdfs:Class ;
rdfs:label "heart growth" ;
rdfs:comment "The increase in size or mass of the heart." ;
rdfs:subClassOf obo:GO_0035265 , obo:GO_0048589 .
obo:GO_0060299 a rdfs:Class ;
rdfs:label "negative regulation of sarcomere organization" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0051494 , obo:GO_0060297 , obo:GO_0065007 , obo:GO_1902116 , obo:GO_1902904 .
obo:GO_2000459 a rdfs:Class ;
rdfs:label "negative regulation of astrocyte chemotaxis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0050922 , obo:GO_0065007 , obo:GO_1903976 , obo:GO_2000458 .
obo:CHEBI_24840 a rdfs:Class ;
rdfs:label "inorganic sulfate salt" ;
rdfs:subClassOf obo:CHEBI_24839 , obo:CHEBI_35175 .
obo:GO_0002616 a rdfs:Class ;
rdfs:label "regulation of macrophage antigen processing and presentation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002577 , obo:GO_0065007 .
obo:GO_0008289 a rdfs:Class ;
rdfs:label "lipid binding" ;
rdfs:comment "Binding to a lipid." ;
rdfs:subClassOf obo:GO_0005488 .
obo:CHEBI_38099 a rdfs:Class ;
rdfs:label "thiadiazoles" ;
rdfs:subClassOf obo:CHEBI_25693 .
obo:PHIPO_0000681 a rdfs:Class ;
rdfs:label "resistance to nystatin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to nystatin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0010977 a rdfs:Class ;
rdfs:label "negative regulation of neuron projection development" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ;
rdfs:subClassOf obo:GO_0010975 , obo:GO_0031345 , obo:GO_0065007 .
obo:CHEBI_33402 a rdfs:Class ;
rdfs:label "sulfur oxoacid" ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_33484 .
obo:CHEBI_71337 a rdfs:Class ;
rdfs:label "minocycline(1-)" ;
rdfs:comment "An organic anion that is the conjugate base of minocycline, obtained by deprotonation of the two enolic hydroxy groups and protonation of the non-aromatic tertiary amino group." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:CHEBI_50267 a rdfs:Class ;
rdfs:label "protective agent" ;
rdfs:comment "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0071542 a rdfs:Class ;
rdfs:label "dopaminergic neuron differentiation" ;
rdfs:comment "The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030182 .
obo:GO_0006413 a rdfs:Class ;
rdfs:label "translational initiation" ;
rdfs:comment "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." ;
rdfs:subClassOf obo:GO_0008152 .
obo:PHIPO_0001049 a rdfs:Class ;
rdfs:label "unicellular colony shape phenotype"@en ;
rdfs:comment "A single species population phenotype affecting the shape of a colony of unicellular individuals." ;
rdfs:subClassOf obo:PHIPO_0001208 .
obo:GO_0010506 a rdfs:Class ;
rdfs:label "regulation of autophagy" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0065007 .
obo:PHIPO_0000444 a rdfs:Class ;
rdfs:label "decreased number of asexual pathogen spores within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is decreased." ;
rdfs:subClassOf obo:PHIPO_0000448 .
obo:UBERON_0004766 a rdfs:Class ;
rdfs:label "cranial bone" ;
rdfs:comment "A bone that is part of a cranium." ;
rdfs:subClassOf obo:UBERON_0001474 .
obo:GO_0150147 a rdfs:Class ;
rdfs:label "cell-cell junction disassembly" ;
rdfs:comment "The disaggregation of a cell-cell junction into its constituent components." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0045216 , obo:GO_0150146 .
obo:UBERON_0001017 a rdfs:Class ;
rdfs:label "central nervous system" ;
rdfs:comment "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0011216 .
obo:CHEBI_24532 a rdfs:Class ;
rdfs:label "organic heterocyclic compound" ;
rdfs:comment "A cyclic compound having as ring members atoms of carbon and at least of one other element." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_33832 , obo:CHEBI_5686 .
obo:GO_0071897 a rdfs:Class ;
rdfs:label "DNA biosynthetic process" ;
rdfs:comment "The biosynthetic process resulting in the formation of DNA." ;
rdfs:subClassOf obo:GO_0006259 , obo:GO_0009058 , obo:GO_0141187 .
obo:UBERON_0003564 a rdfs:Class ;
rdfs:label "diencephalon dura mater" ;
rdfs:comment "A dura mater that is part of a diencephalon [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002363 , obo:UBERON_0003290 , obo:UBERON_0003561 .
obo:UBERON_0003068 a rdfs:Class ;
rdfs:label "axial mesoderm" ;
rdfs:comment "The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0008504 a rdfs:Class ;
rdfs:label "monoamine transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022804 , obo:GO_0022857 .
obo:GO_1903055 a rdfs:Class ;
rdfs:label "positive regulation of extracellular matrix organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of extracellular matrix organization." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1903053 .
obo:CL_4307046 a rdfs:Class ;
rdfs:label "Astro-TE NN_3 Zic4 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Ranbp3l (Mmus), Emx2os (Mmus), Zic4 (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Zic4. These cells are located in the Lateral septal complex, Isocortex, Olfactory areas , in or close to the regions: Lateral septal nucleus, rostral (rostroventral) part . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5226 Astro-TE NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301593 .
obo:GO_0043482 a rdfs:Class ;
rdfs:label "cellular pigment accumulation" ;
rdfs:comment "The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus." ;
rdfs:subClassOf obo:GO_0033059 , obo:GO_0043476 , obo:GO_0051716 .
obo:UBERON_0018544 a rdfs:Class ;
rdfs:label "trigeminal nerve muscle" ;
rdfs:comment "Muscle innervated by the trigeminal nerve (Cranial Nerve V)." ;
rdfs:subClassOf obo:UBERON_0001630 .
obo:GO_0044877 a rdfs:Class ;
rdfs:label "protein-containing complex binding" ;
rdfs:comment "Binding to a macromolecular complex." ;
rdfs:subClassOf obo:GO_0005488 .
obo:UBERON_0007026 a rdfs:Class ;
rdfs:label "presumptive gut" ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_0021608 a rdfs:Class ;
rdfs:label "accessory nerve formation" ;
rdfs:comment "The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." ;
rdfs:subClassOf obo:GO_0021603 , obo:GO_0048646 .
obo:PHIPO_0001206 a rdfs:Class ;
rdfs:label "normal filament morphology"@en ;
rdfs:comment "A single species phenotype where the morphology of a cell is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001376 .
obo:CHEBI_27081 a rdfs:Class ;
rdfs:label "transition element atom" ;
rdfs:comment "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell." ;
rdfs:subClassOf obo:CHEBI_33521 .
obo:UBERON_0010000 a rdfs:Class ;
rdfs:label "multicellular anatomical structure" ;
rdfs:comment "An anatomical structure that has more than one cell as a part." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0008061 a rdfs:Class ;
rdfs:label "chitin binding" ;
rdfs:comment "Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." ;
rdfs:subClassOf obo:GO_0097367 .
obo:GO_1900149 a rdfs:Class ;
rdfs:label "positive regulation of Schwann cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of Schwann cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900147 , obo:GO_1903977 .
obo:GO_0035441 a rdfs:Class ;
rdfs:label "cell migration involved in vasculogenesis" ;
rdfs:comment "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes." ;
rdfs:subClassOf obo:GO_0016477 .
obo:GO_0060128 a rdfs:Class ;
rdfs:label "corticotropin hormone secreting cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin." ;
rdfs:subClassOf obo:GO_0030154 .
obo:CHEBI_60251 a rdfs:Class ;
rdfs:label "guanidinium ion" ;
rdfs:comment "R = C or H. The iminium ion resulting from the protonation of one of the imine nitrogens of guanidine or its derivatives." ;
rdfs:subClassOf obo:CHEBI_35286 .
obo:UBERON_0001701 a rdfs:Class ;
rdfs:label "glossopharyngeal ganglion" ;
rdfs:comment "The group of neuron cell bodies associated with the ninth cranial nerve." ;
rdfs:subClassOf obo:UBERON_0001714 , obo:UBERON_0009127 .
obo:PHIPO_0001072 a rdfs:Class ;
rdfs:label "obsolete inviable host organism with pathogen" ;
rdfs:comment "A pathogen host interaction organism viability phenotype where a host organism is inviable in the presence of a pathogen." .
obo:GO_0042117 a rdfs:Class ;
rdfs:label "monocyte activation" ;
rdfs:comment "The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0002274 .
obo:UBERON_0001033 a rdfs:Class ;
rdfs:label "gustatory system" ;
rdfs:comment "The sensory system for the sense of taste." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:CL_4310146 a rdfs:Class ;
rdfs:label "AMY-SLEA-BNST GABA GABAergic interneuron (Primate)" ;
rdfs:comment "A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST GABA." ;
rdfs:subClassOf obo:CL_0011005 .
obo:GO_0006518 a rdfs:Class ;
rdfs:label "peptide metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0031339 a rdfs:Class ;
rdfs:label "negative regulation of vesicle fusion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0031338 , obo:GO_0051051 , obo:GO_0065007 .
obo:PHIPO_0000678 a rdfs:Class ;
rdfs:label "resistance to paromomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to paromomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0050671 a rdfs:Class ;
rdfs:label "positive regulation of lymphocyte proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of lymphocyte proliferation." ;
rdfs:subClassOf obo:GO_0032946 , obo:GO_0050670 , obo:GO_0051251 , obo:GO_0065007 .
obo:CHEBI_20854 a rdfs:Class ;
rdfs:label "ATP synthase inhibitor" ;
rdfs:comment "A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase." ;
rdfs:subClassOf obo:CHEBI_25355 , obo:CHEBI_73216 .
obo:UBERON_0003499 a rdfs:Class ;
rdfs:label "brain blood vessel" ;
rdfs:comment "A blood vessel that is part of a brain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:GO_0008088 a rdfs:Class ;
rdfs:label "axo-dendritic transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules in neuron projections." ;
rdfs:subClassOf obo:GO_0010970 , obo:GO_0046907 .
obo:GO_0030658 a rdfs:Class ;
rdfs:label "transport vesicle membrane" ;
rdfs:comment "The lipid bilayer surrounding a transport vesicle." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0030659 , obo:GO_0098588 .
obo:CHEBI_35297 a rdfs:Class ;
rdfs:label "acene" ;
rdfs:comment "A polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement." ;
rdfs:subClassOf obo:CHEBI_35296 , obo:CHEBI_51269 .
obo:CHEBI_38129 a rdfs:Class ;
rdfs:label "dithiocarbamic ester" ;
rdfs:comment "Any ester derived from a member of the class of dithiocarbamic acids by formal replacement of the -SH group by -SR, where R is an organyl group." ;
rdfs:subClassOf obo:CHEBI_38127 .
obo:GO_0006399 a rdfs:Class ;
rdfs:label "tRNA metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established." ;
rdfs:subClassOf obo:GO_0016070 .
obo:GO_0042479 a rdfs:Class ;
rdfs:label "positive regulation of eye photoreceptor cell development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0042478 , obo:GO_0046534 , obo:GO_0065007 .
obo:PHIPO_0001296 a rdfs:Class ;
rdfs:label "resistance to arborcandin C"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to arborcandin C. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0099612 a rdfs:Class ;
rdfs:label "protein localization to axon" ;
rdfs:comment "A process in which a protein is transported to or maintained in a location within an axon." ;
rdfs:subClassOf obo:GO_0008104 .
obo:GO_0016874 a rdfs:Class ;
rdfs:label "ligase activity" ;
rdfs:comment "Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient." ;
rdfs:subClassOf obo:GO_0003824 .
obo:UBERON_0005194 a rdfs:Class ;
rdfs:label "thoracic vein" ;
rdfs:comment "A vein that is part of a thorax [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0003834 .
obo:GO_0048585 a rdfs:Class ;
rdfs:label "negative regulation of response to stimulus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0048583 , obo:GO_0065007 .
obo:UBERON_0003721 a rdfs:Class ;
rdfs:label "lingual nerve" ;
rdfs:comment "The lingual nerve is a branch of the mandibular nerve (CN V3), itself a branch of the trigeminal nerve, which supplies sensory innervation to the tongue. It also carries fibers from the facial nerve, which return taste information from the anterior two thirds of the tongue." ;
rdfs:subClassOf obo:UBERON_0001021 , obo:UBERON_0011779 .
obo:GO_0061054 a rdfs:Class ;
rdfs:label "dermatome development" ;
rdfs:comment "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CL_0002077 a rdfs:Class ;
rdfs:label "ecto-epithelial cell" ;
rdfs:comment "An epithelial cell derived from ectoderm." ;
rdfs:subClassOf obo:CL_0000066 .
obo:GO_0051451 a rdfs:Class ;
rdfs:label "myoblast migration" ;
rdfs:comment "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ;
rdfs:subClassOf obo:GO_0014812 , obo:GO_0016477 .
obo:PHIPO_0000824 a rdfs:Class ;
rdfs:label "sensitive to tiamulin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tiamulin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0051956 a rdfs:Class ;
rdfs:label "negative regulation of amino acid transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051953 , obo:GO_0051955 , obo:GO_0065007 .
obo:GO_0032230 a rdfs:Class ;
rdfs:label "positive regulation of synaptic transmission, GABAergic" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ;
rdfs:subClassOf obo:GO_0032228 , obo:GO_0050806 , obo:GO_0065007 .
obo:CL_4023181 a rdfs:Class ;
rdfs:label "hypendymal cell" ;
rdfs:comment "A neurecto-epithelial cell that is part of the basal layer of the subcommissural organ and specializes in the secretion of proteins into the subarachnoid space. Hypendymal cells have similar characteristics to ependymal cells and express SCO-spondin." ;
rdfs:subClassOf obo:CL_0000710 , obo:CL_0002319 .
obo:CL_0019019 a rdfs:Class ;
rdfs:label "tracheobronchial smooth muscle cell"@en ;
rdfs:comment "A smooth muscle cell that is part of the tracheobronchial tree." ;
rdfs:subClassOf obo:CL_0000192 .
obo:CHEBI_26650 a rdfs:Class .
obo:GO_0045684 a rdfs:Class ;
rdfs:label "positive regulation of epidermis development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of epidermis development." ;
rdfs:subClassOf obo:GO_0045682 , obo:GO_0051094 , obo:GO_0065007 .
obo:GO_0050804 a rdfs:Class ;
rdfs:label "modulation of chemical synaptic transmission" ;
rdfs:comment "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0099177 .
obo:GO_0035736 a rdfs:Class ;
rdfs:label "cell proliferation involved in compound eye morphogenesis" ;
rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis." ;
rdfs:subClassOf obo:GO_0008283 .
obo:GO_0060538 a rdfs:Class ;
rdfs:label "skeletal muscle organ development" ;
rdfs:comment "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." ;
rdfs:subClassOf obo:GO_0007517 , obo:GO_0048856 .
obo:GO_0098928 a rdfs:Class ;
rdfs:label "presynaptic signal transduction" ;
rdfs:comment "Signal transduction in which the initial step occurs in a presynapse." ;
rdfs:subClassOf obo:GO_0007165 .
obo:GO_2000818 a rdfs:Class ;
rdfs:label "negative regulation of myoblast proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0065007 , obo:GO_2000291 .
obo:GO_0030010 a rdfs:Class ;
rdfs:label "establishment of cell polarity" ;
rdfs:comment "The specification and formation of anisotropic intracellular organization or cell growth patterns." ;
rdfs:subClassOf obo:GO_0007163 .
obo:CL_0002477 a rdfs:Class ;
rdfs:label "adipose macrophage" ;
rdfs:comment "A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive." ;
rdfs:subClassOf obo:CL_0000864 .
obo:CHEBI_48908 a rdfs:Class ;
rdfs:label "triazolobenzothiazole" ;
rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38101 , obo:CHEBI_38106 .
obo:CHEBI_23666 a rdfs:Class ;
rdfs:label "diamine" ;
rdfs:comment "Any polyamine that contains two amino groups." ;
rdfs:subClassOf obo:CHEBI_88061 .
obo:UBERON_0003726 a rdfs:Class ;
rdfs:label "thoracic nerve" ;
rdfs:comment "The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls." ;
rdfs:subClassOf obo:UBERON_0001780 .
obo:GO_0021578 a rdfs:Class ;
rdfs:label "hindbrain maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:GO_1905071 a rdfs:Class ;
rdfs:label "tight junction disassembly" ;
rdfs:comment "The disaggregation of an tight junction into its constituent components." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0120193 , obo:GO_0150147 .
obo:PHIPO_0000232 a rdfs:Class ;
rdfs:label "increased level of pathogen deoxynivalenol within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen produced deoxynivalenol usually present during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001046 .
obo:GO_0060123 a rdfs:Class ;
rdfs:label "regulation of growth hormone secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090276 .
obo:UBERON_0013151 a rdfs:Class ;
rdfs:label "choroidal artery" ;
rdfs:comment "One of two arteries (anterior and posterior choroidal artery) that supply blood to the choroid plexus, optic tract, hippocampus, globus pallidus, and other various brain regions." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:CHEBI_102484 a rdfs:Class ;
rdfs:label "sulfisoxazole" ;
rdfs:comment "A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms." ;
rdfs:subClassOf obo:CHEBI_55373 , obo:CHEBI_87228 .
obo:PHIPO_0000230 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host interaction toxin biosynthetic process" ;
rdfs:comment "A pathogen host interaction phenotype in which the toxin biosynthetic process is normal (i.e. same as the wild type)." .
obo:GO_0075054 a rdfs:Class ;
rdfs:label "modulation of penetration peg formation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0052372 , obo:GO_0065007 .
a rdfs:Class ;
rdfs:label "Periventricular region" ;
rdfs:subClassOf obo:BFO_0000004 .
obo:UBERON_0003357 a rdfs:Class ;
rdfs:label "epithelium of tongue" ;
rdfs:comment "An epithelium that is part of a tongue [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003929 , obo:UBERON_0019304 .
obo:PHIPO_0000175 a rdfs:Class ;
rdfs:label "obsolete normal pathogen growth on host surface" ;
rdfs:comment "A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is normal." .
obo:CL_0008017 a rdfs:Class ;
rdfs:label "adult skeletal muscle myoblast" ;
rdfs:comment "A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers." ;
rdfs:subClassOf obo:CL_0000056 , obo:CL_0000188 , obo:CL_0000515 .
obo:UBERON_0001833 a rdfs:Class ;
rdfs:label "lip" ;
rdfs:comment "One of the two fleshy folds which surround the opening of the mouth." ;
rdfs:subClassOf obo:UBERON_0003102 .
obo:UBERON_0005867 a rdfs:Class ;
rdfs:label "mandibular prominence" ;
rdfs:comment "The paired ventral prominences formed by bifurcation of the first pharyngeal arches in the embryo; the two prominences unite ventrally and fuse to form the mandible and lower lip." ;
rdfs:subClassOf obo:UBERON_0012314 .
obo:CHEBI_3515 a rdfs:Class ;
rdfs:label "cefuroxime" ;
rdfs:comment "A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain." ;
rdfs:subClassOf obo:CHEBI_23003 , obo:CHEBI_24129 , obo:CHEBI_28084 , obo:CHEBI_36816 .
obo:CL_4030050 a rdfs:Class ;
rdfs:label "D1/D2-hybrid medium spiny neuron" ;
rdfs:comment "A medium spiny neuron that expresses both DRD1 and DRD2 and is part of an extra-striosomal part of dorsal striatum." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_1001474 .
obo:GO_0061534 a rdfs:Class ;
rdfs:label "gamma-aminobutyric acid secretion, neurotransmission" ;
rdfs:comment "The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0007269 , obo:GO_0014051 .
obo:GO_0060421 a rdfs:Class ;
rdfs:label "positive regulation of heart growth" ;
rdfs:comment "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." ;
rdfs:subClassOf obo:GO_0046622 , obo:GO_0060420 , obo:GO_0065007 .
obo:GO_0060915 a rdfs:Class ;
rdfs:label "mesenchymal cell differentiation involved in lung development" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." ;
rdfs:subClassOf obo:GO_0048762 .
obo:GO_1902930 a rdfs:Class ;
rdfs:label "regulation of alcohol biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of alcohol biosynthetic process." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0062012 , obo:GO_0065007 .
obo:GO_1905320 a rdfs:Class ;
rdfs:label "regulation of mesenchymal stem cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:CHEBI_100246 a rdfs:Class ;
rdfs:label "norfloxacin" ;
rdfs:comment "A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase." ;
rdfs:subClassOf obo:CHEBI_23765 , obo:CHEBI_26512 , obo:CHEBI_46848 , obo:CHEBI_86324 , obo:CHEBI_87211 .
obo:GO_1905628 a rdfs:Class ;
rdfs:label "negative regulation of serotonin biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0065007 , obo:GO_1905627 .
obo:GO_0003002 a rdfs:Class ;
rdfs:label "regionalization" ;
rdfs:comment "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." ;
rdfs:subClassOf obo:GO_0007389 .
obo:GO_0060170 a rdfs:Class ;
rdfs:label "ciliary membrane" ;
rdfs:comment "The portion of the plasma membrane surrounding a cilium." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031253 , obo:GO_0098588 .
obo:PATO_0000033 a rdfs:Class ;
rdfs:label "concentration of" ;
rdfs:comment "A quality inhering in a substance by virtue of the amount of the bearer's there is mixed with another substance." ;
rdfs:subClassOf obo:PATO_0000070 .
obo:GO_0034504 a rdfs:Class ;
rdfs:label "protein localization to nucleus" ;
rdfs:comment "A process in which a protein transports or maintains the localization of another protein to the nucleus." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033365 .
obo:CHEBI_25698 a rdfs:Class ;
rdfs:label "ether" ;
rdfs:comment "An organooxygen compound with formula ROR, where R is not hydrogen." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:CHEBI_83060 a rdfs:Class ;
rdfs:label "dithiocarbamate salt" ;
rdfs:comment "Any salt derived from a member of the class of dithiocarbamic acids by the formal replacement of the hydrogen of the dithiocarboxy group by a metal." ;
rdfs:subClassOf obo:CHEBI_24868 .
obo:UBERON_0005289 a rdfs:Class ;
rdfs:label "tela choroidea of telencephalic ventricle" ;
rdfs:comment "Tela chorioidea that lines the telencephalic ventricle." ;
rdfs:subClassOf obo:UBERON_0005283 .
obo:GO_0051606 a rdfs:Class ;
rdfs:label "detection of stimulus" ;
rdfs:comment "The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0050896 .
obo:GO_0035372 a rdfs:Class ;
rdfs:label "protein localization to microtubule" ;
rdfs:comment "A process in which a protein is transported to, or maintained at, a microtubule." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0072698 .
obo:GO_0055023 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle tissue growth" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth." ;
rdfs:subClassOf obo:GO_0055021 , obo:GO_0060421 , obo:GO_0065007 .
obo:PHIPO_0001427 a rdfs:Class ;
rdfs:label "abnormal hyphal branching"@en ;
rdfs:comment "A single species cell morphology phenotype in which fungal hyphae branching is abnormal." ;
rdfs:subClassOf obo:PHIPO_0001205 .
obo:GO_0021718 a rdfs:Class ;
rdfs:label "superior olivary nucleus development" ;
rdfs:comment "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048857 .
obo:CL_0008001 a rdfs:Class ;
rdfs:label "hematopoietic precursor cell" ;
rdfs:comment "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." ;
rdfs:subClassOf obo:CL_0000988 .
obo:GO_0065009 a rdfs:Class ;
rdfs:label "regulation of molecular function" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ;
rdfs:subClassOf obo:GO_0065007 .
obo:GO_1905940 a rdfs:Class ;
rdfs:label "negative regulation of gonad development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1905939 , obo:GO_2000242 .
obo:UBERON_0006268 a rdfs:Class ;
rdfs:label "notochordal process" ;
rdfs:comment "A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot." ;
rdfs:subClassOf obo:UBERON_0005423 .
obo:GO_0022857 a rdfs:Class ;
rdfs:label "transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0005215 .
obo:GO_0061351 a rdfs:Class ;
rdfs:label "neural precursor cell proliferation" ;
rdfs:comment "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." ;
rdfs:subClassOf obo:GO_0008283 .
obo:UBERON_0004086 a rdfs:Class ;
rdfs:label "brain ventricle" ;
rdfs:comment "One of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that like it are derived from the medullary canal of the embryo, that are lined with an epithelial ependyma, and that contain a serous fluid." ;
rdfs:subClassOf obo:UBERON_0003947 , obo:UBERON_0005358 .
obo:CHEBI_64257 a rdfs:Class ;
rdfs:label "tunicamycin C2" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a hexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:NCBITaxon_10090 a rdfs:Class ;
rdfs:label "Mus musculus" ;
rdfs:subClassOf obo:NCBITaxon_862507 .
obo:GO_0002265 a rdfs:Class ;
rdfs:label "astrocyte activation involved in immune response" ;
rdfs:comment "A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0002263 , obo:GO_0048143 .
obo:CHEBI_78295 a rdfs:Class ;
rdfs:label "food component" ;
rdfs:comment "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." ;
rdfs:subClassOf obo:CHEBI_52211 .
obo:PATO_0000947 a rdfs:Class ;
rdfs:label "elliptic" ;
rdfs:comment "A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section." ;
rdfs:subClassOf obo:PATO_0002318 .
obo:GO_0045807 a rdfs:Class ;
rdfs:label "positive regulation of endocytosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endocytosis." ;
rdfs:subClassOf obo:GO_0030100 , obo:GO_0051050 , obo:GO_0051130 , obo:GO_0065007 .
obo:CHEBI_70728 a rdfs:Class ;
rdfs:label "actin polymerisation inhibitor" ;
rdfs:comment "Any substance that inhibits the polymerisation of the protein actin." ;
rdfs:subClassOf obo:CHEBI_35222 .
obo:PHIPO_0000044 a rdfs:Class ;
rdfs:label "normal reproduction phenotype"@en ;
rdfs:comment "A single species phenotype where reproduction is normal (indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000161 .
obo:CHEBI_60240 a rdfs:Class ;
rdfs:label "divalent metal cation" ;
rdfs:comment "A metal cation with a valence of two." ;
rdfs:subClassOf obo:CHEBI_25213 , obo:CHEBI_64641 .
obo:CL_0000513 a rdfs:Class ;
rdfs:label "cardiac muscle myoblast" ;
rdfs:comment "A precursor cell destined to differentiate into cardiac muscle cell." ;
rdfs:subClassOf obo:CL_0000056 , obo:CL_0002494 , obo:CL_0010021 .
obo:UBERON_0005434 a rdfs:Class ;
rdfs:label "cervical region" ;
rdfs:subClassOf obo:UBERON_0011676 .
obo:GO_1900923 a rdfs:Class ;
rdfs:label "regulation of glycine import across plasma membrane" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glycine import into a cell." ;
rdfs:subClassOf obo:GO_0010958 , obo:GO_0032890 , obo:GO_0065007 .
obo:GO_0035909 a rdfs:Class ;
rdfs:label "aorta morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048844 .
obo:UBERON_0002094 a rdfs:Class ;
rdfs:label "interventricular septum" ;
rdfs:comment "Cardiac septum which separates the right ventricle from the left ventricle.[FMA]." ;
rdfs:subClassOf obo:UBERON_0002099 .
obo:UBERON_0011215 a rdfs:Class ;
rdfs:label "central nervous system cell part cluster" ;
rdfs:comment "A multi cell part structure that is part of a central nervous system." ;
rdfs:subClassOf obo:UBERON_0005162 .
obo:UBERON_0005419 a rdfs:Class ;
rdfs:label "pectoral appendage bud" ;
rdfs:comment "A limb bud that develops into a forelimb or pectoral fin." ;
rdfs:subClassOf obo:UBERON_0004357 .
obo:UBERON_0001873 a rdfs:Class ;
rdfs:label "caudate nucleus" ;
rdfs:comment "Subcortical nucleus of telecephalic origin consisting of an elongated gray mass lying lateral to and bordering the lateral ventricle. It is divided into a head, body and tail in some species." ;
rdfs:subClassOf obo:UBERON_0009663 .
obo:GO_1905955 a rdfs:Class ;
rdfs:label "negative regulation of endothelial tube morphogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis." ;
rdfs:subClassOf obo:GO_0051241 , obo:GO_0065007 , obo:GO_1901509 , obo:GO_1905331 .
obo:CL_4307064 a rdfs:Class ;
rdfs:label "Tanycyte NN_1 Glp1r tanycyte (Mmus)" ;
rdfs:comment "A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C230072F16Rik (Mmus), Glp1r (Mmus). It is distinguished from other Tanycyte NN_1 cells by expression of Glp1r. These cells are located in the Hypothalamus, brain , in or close to the regions: Anteroventral periventricular nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5244 Tanycyte NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301602 .
obo:GO_0033033 a rdfs:Class ;
rdfs:label "negative regulation of myeloid cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process." ;
rdfs:subClassOf obo:GO_0033032 , obo:GO_0043066 , obo:GO_0065007 .
obo:GO_0014003 a rdfs:Class ;
rdfs:label "oligodendrocyte development" ;
rdfs:comment "The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system." ;
rdfs:subClassOf obo:GO_0021782 , obo:GO_0032502 .
obo:PHIPO_0000537 a rdfs:Class ;
rdfs:label "resistance to captan"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to captan. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_33566 a rdfs:Class .
obo:CHEBI_3732 a rdfs:Class ;
rdfs:label "clarithromycin" ;
rdfs:comment "The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis." ;
rdfs:subClassOf obo:CHEBI_25105 .
obo:CHEBI_46687 a rdfs:Class ;
rdfs:label "diazaalkane" ;
rdfs:subClassOf obo:CHEBI_39474 .
obo:GO_0000768 a rdfs:Class ;
rdfs:label "syncytium formation by cell-cell fusion" ;
rdfs:comment "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ;
rdfs:subClassOf obo:GO_0140253 .
obo:CL_4301613 a rdfs:Class ;
rdfs:label "myelin-forming oligodendrocyte (Mmus)" ;
rdfs:comment "A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Sec14l5 (Mmus), 9630013A20Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1183 MFOL NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4072002 , obo:CL_4300367 .
obo:GO_0032055 a rdfs:Class ;
rdfs:label "negative regulation of translation in response to stress" ;
rdfs:comment "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0017148 , obo:GO_0043555 , obo:GO_0065007 .
obo:UBERON_0000971 a rdfs:Class ;
rdfs:label "ommatidium" ;
rdfs:comment "The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells." ;
rdfs:subClassOf obo:UBERON_0000970 , obo:UBERON_0002536 .
obo:CHEBI_48355 a rdfs:Class ;
rdfs:label "non-polar solvent" ;
rdfs:subClassOf obo:CHEBI_46787 .
obo:GO_1902257 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic process involved in outflow tract morphogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902256 , obo:GO_1902338 .
obo:UBERON_0005256 a rdfs:Class ;
rdfs:label "trunk mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a developing trunk." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005291 .
obo:CHEBI_24318 a rdfs:Class ;
rdfs:label "glutamine family amino acid" ;
rdfs:comment "An L-α-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class." ;
rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_83813 .
obo:GO_1990010 a rdfs:Class ;
rdfs:label "compound eye retinal cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a compound eye retinal cell." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_1990009 .
obo:GO_0032092 a rdfs:Class ;
rdfs:label "positive regulation of protein binding" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein binding." ;
rdfs:subClassOf obo:GO_0043393 , obo:GO_0051099 , obo:GO_0065007 .
obo:GO_0048630 a rdfs:Class ;
rdfs:label "skeletal muscle tissue growth" ;
rdfs:comment "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size." ;
rdfs:subClassOf obo:GO_0048589 .
obo:CHEBI_9948 a rdfs:Class ;
rdfs:label "verapamil" ;
rdfs:comment "A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine." ;
rdfs:subClassOf obo:CHEBI_50860 , obo:CHEBI_60911 .
obo:CHEBI_39410 a rdfs:Class ;
rdfs:label "1,2,4-triazines" ;
rdfs:comment "Any compound with a 1,2,4-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 2 and 4 of the core benzene ring structure." ;
rdfs:subClassOf obo:CHEBI_38102 .
obo:UBERON_0005058 a rdfs:Class ;
rdfs:label "hemolymphoid system gland" ;
rdfs:comment "A gland that is part of a hemolymphoid system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:UBERON_0036225 a rdfs:Class ;
rdfs:label "respiratory system gland" ;
rdfs:comment "Any gland that is part os the respiratory system." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:UBERON_0002813 a rdfs:Class ;
rdfs:label "right cerebral hemisphere" ;
rdfs:comment "A cerebral hemisphere that is in the right side of a brain." ;
rdfs:subClassOf obo:UBERON_0001869 .
obo:GO_1900450 a rdfs:Class ;
rdfs:label "negative regulation of glutamate receptor signaling pathway" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway." ;
rdfs:subClassOf obo:GO_0009968 , obo:GO_0065007 , obo:GO_1900449 .
obo:UBERON_0000949 a rdfs:Class ;
rdfs:label "endocrine system" ;
rdfs:comment "Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity." ;
rdfs:subClassOf obo:UBERON_0015204 .
obo:UBERON_0004725 a rdfs:Class ;
rdfs:label "piriform cortex" ;
rdfs:comment "The subdivision of the laminated olfactory cortex with only three main layers that receive monosynaptic input from the olfactory bulb via the lateral olfactory tract; it is located bilaterally in the ventrolateral forebrain and is commonly divided into anterior and posterior regions." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:UBERON_0006913 a rdfs:Class ;
rdfs:label "lip epithelium" ;
rdfs:comment "An epithelium that is part of a lip." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003929 .
obo:GO_0043650 a rdfs:Class ;
rdfs:label "dicarboxylic acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0043648 , obo:GO_0046394 .
obo:GO_0035990 a rdfs:Class ;
rdfs:label "tendon cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance." ;
rdfs:subClassOf obo:GO_0030154 .
obo:PR_P01731 a rdfs:Class ;
rdfs:label "T-cell surface glycoprotein CD8 alpha chain (mouse)" ;
rdfs:comment "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001084 , obo:PR_000029032 .
obo:UBERON_0011814 a rdfs:Class ;
rdfs:label "non-neurogenic ectodermal placode" ;
rdfs:comment "Ectodermal placode that does not develop into a component of the nervous system." ;
rdfs:subClassOf obo:UBERON_0005085 .
obo:UBERON_0004026 a rdfs:Class ;
rdfs:label "caudal ganglionic eminence" ;
rdfs:comment "The caudally located, distinct elevation of a transient proliferating cell mass of the fetal subventricular zone, located adjacent to the lateral ventricle." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:UBERON_0010316 a rdfs:Class ;
rdfs:label "germ layer / neural crest" ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005291 .
obo:UBERON_0004765 a rdfs:Class ;
rdfs:label "skeletal element" ;
rdfs:comment "Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:GO_1905516 a rdfs:Class ;
rdfs:label "positive regulation of fertilization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of fertilization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080154 , obo:GO_2000243 .
obo:GO_0014897 a rdfs:Class ;
rdfs:label "striated muscle hypertrophy" ;
rdfs:comment "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." ;
rdfs:subClassOf obo:GO_0014896 .
obo:UBERON_0005487 a rdfs:Class ;
rdfs:label "vitelline vein" ;
rdfs:comment "The paired veins that carry blood from the yolk sac back to the embryo." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0004365 , obo:UBERON_0013140 .
obo:CHEBI_87198 a rdfs:Class ;
rdfs:label "phthalimide fungicide" ;
rdfs:comment "A dicarboximide fungicide whose structure contains a phthalimide derivative." ;
rdfs:subClassOf obo:CHEBI_87195 .
obo:CL_0000365 a rdfs:Class ;
rdfs:label "animal zygote" ;
rdfs:comment "Diploid cell produced by the fusion of sperm cell nucleus and egg cell." ;
rdfs:subClassOf obo:CL_0000007 , obo:CL_0000255 , obo:CL_0010017 .
obo:GO_0002089 a rdfs:Class ;
rdfs:label "lens morphogenesis in camera-type eye" ;
rdfs:comment "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PHIPO_0001165 a rdfs:Class ;
rdfs:label "abnormal host seed development induced by pathogen"@en ;
rdfs:comment "A host reproductive phenotype with pathogen where the process of host seed development is abnormal (GO:0048316)." ;
rdfs:subClassOf obo:PHIPO_0001250 .
obo:UBERON_0001417 a rdfs:Class ;
rdfs:label "skin of neck" ;
rdfs:comment "A zone of skin that is part of a neck [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000014 .
obo:GO_0021707 a rdfs:Class ;
rdfs:label "cerebellar granule cell differentiation" ;
rdfs:comment "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex." ;
rdfs:subClassOf obo:GO_0021533 , obo:GO_0021953 , obo:GO_0030154 , obo:GO_1905962 .
obo:PATO_0001551 a rdfs:Class ;
rdfs:label "increased sensitivity of a process" ;
rdfs:comment "A sensitivity of a process which is higher than normal or average." ;
rdfs:subClassOf obo:PATO_0001457 , obo:PATO_0002304 .
obo:UBERON_0002409 a rdfs:Class ;
rdfs:label "pericardial fluid" ;
rdfs:comment "Transudate contained in the pericardial cavity.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000463 , obo:UBERON_0007794 , obo:UBERON_0036217 .
obo:GO_0045168 a rdfs:Class ;
rdfs:label "cell-cell signaling involved in cell fate commitment" ;
rdfs:comment "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." ;
rdfs:subClassOf obo:GO_0007267 .
obo:CHEBI_35406 a rdfs:Class ;
rdfs:label "oxoanion" ;
rdfs:comment "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." ;
rdfs:subClassOf obo:CHEBI_25741 , obo:CHEBI_33273 .
obo:UBERON_0004493 a rdfs:Class ;
rdfs:label "cardiac muscle tissue of myocardium" ;
rdfs:comment "A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001133 .
a rdfs:Class ;
rdfs:label "LHX6" .
obo:GO_0099540 a rdfs:Class ;
rdfs:label "trans-synaptic signaling by neuropeptide" ;
rdfs:comment "Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft." ;
rdfs:subClassOf obo:GO_0099537 , obo:GO_0099538 .
obo:GO_0001817 a rdfs:Class ;
rdfs:label "regulation of cytokine production" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of production of a cytokine." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0051239 , obo:GO_0065007 .
obo:UBERON_0006915 a rdfs:Class ;
rdfs:label "stratified squamous epithelium" ;
rdfs:comment "Multilaminar epithelium which consists of more than one layer of squamous cells only one layer of which is in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, epithelium of wall of esophagus.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000486 , obo:UBERON_0006914 .
obo:GO_2000977 a rdfs:Class ;
rdfs:label "regulation of forebrain neuron differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of forebrain neuron differentiation." ;
rdfs:subClassOf obo:GO_0045664 , obo:GO_0065007 .
obo:GO_1905634 a rdfs:Class ;
rdfs:label "regulation of protein localization to chromatin" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to chromatin." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:UBERON_0006279 a rdfs:Class ;
rdfs:label "pleuroperitoneal canal" ;
rdfs:comment "Each of the canals that links the peritoneal cavity and the caudal part of a pleural cavity." ;
rdfs:subClassOf obo:UBERON_0003914 , obo:UBERON_0005291 .
obo:PHIPO_0001248 a rdfs:Class ;
rdfs:label "pathogen modulation of chitin hydrolysis by host present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which a pathogen effector preventing the hydrolysis of chitin by host chitinases is present." ;
rdfs:subClassOf obo:PHIPO_0001128 , obo:PHIPO_0001247 .
obo:UBERON_8600024 a rdfs:Class ;
rdfs:label "pulmonary venule" ;
rdfs:comment "A venule that is part of a lung and drains oxygenated blood from pulmonary capillaries. A pulmonary venule merges into a pulmonary vein branch that runs in the pulmonary interlobular septa." ;
rdfs:subClassOf obo:UBERON_0001979 , obo:UBERON_0003494 , obo:UBERON_0003512 .
obo:UBERON_0004176 a rdfs:Class ;
rdfs:label "external genitalia" ;
rdfs:comment "The external genitalia are the outer sex organs, such as the penis or vulva in mammals." ;
rdfs:subClassOf obo:UBERON_0003133 .
obo:PHIPO_0000936 a rdfs:Class ;
rdfs:label "cell lysis"@en ;
rdfs:comment "An single species phenotype in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost." ;
rdfs:subClassOf obo:PHIPO_0001222 .
obo:GO_0021651 a rdfs:Class ;
rdfs:label "rhombomere 1 morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0021593 .
obo:GO_0002609 a rdfs:Class ;
rdfs:label "positive regulation of myeloid dendritic cell antigen processing and presentation" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002606 , obo:GO_0002607 , obo:GO_0065007 .
obo:GO_0090027 a rdfs:Class ;
rdfs:label "negative regulation of monocyte chemotaxis" ;
rdfs:comment "Any process that decreases the frequency, rate, or extent of monocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0002689 , obo:GO_0065007 , obo:GO_0071676 , obo:GO_0090025 .
obo:GO_0035989 a rdfs:Class ;
rdfs:label "tendon development" ;
rdfs:comment "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0061448 .
obo:UBERON_0011695 a rdfs:Class ;
rdfs:label "embryonic cardiovascular system" ;
rdfs:comment "A cardiovascular system that is part of a conceptus." ;
rdfs:subClassOf obo:UBERON_0004535 .
obo:GO_1902033 a rdfs:Class ;
rdfs:label "regulation of hematopoietic stem cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0072091 .
obo:CHEBI_36823 a rdfs:Class ;
rdfs:label "pseudohalo group" ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:GO_0048745 a rdfs:Class ;
rdfs:label "smooth muscle tissue development" ;
rdfs:comment "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060537 .
obo:GO_0034306 a rdfs:Class ;
rdfs:label "regulation of sexual sporulation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae." ;
rdfs:subClassOf obo:GO_0043937 , obo:GO_0051445 , obo:GO_0065007 .
obo:PHIPO_0000142 a rdfs:Class ;
rdfs:label "RNA binding phenotype"@en ;
rdfs:comment "A single organism phenotype that affects RNA binding. The relevant gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000158 .
obo:CHEBI_26513 a rdfs:Class ;
rdfs:label "quinolines" ;
rdfs:comment "A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_38101 .
obo:GO_0008152 a rdfs:Class ;
rdfs:label "metabolic process" ;
rdfs:comment "A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation." ;
rdfs:subClassOf obo:GO_0009987 .
obo:PHIPO_0001113 a rdfs:Class ;
rdfs:label "host defense induced acidification in phagolysome present"@en ;
rdfs:comment "A pathogen host interaction phenotype where the host induces a pH decrease within the host phagolysome in response to pathogen colonization." ;
rdfs:subClassOf obo:PHIPO_0001108 .
obo:UBERON_0001802 a rdfs:Class ;
rdfs:label "posterior segment of eyeball" ;
rdfs:comment "Any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive)." ;
rdfs:subClassOf obo:UBERON_0000063 .
obo:CL_0002478 a rdfs:Class ;
rdfs:label "F4/80-negative adipose macrophage" ;
rdfs:comment "An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions." ;
rdfs:subClassOf obo:CL_0002477 .
obo:CHEBI_47017 a rdfs:Class ;
rdfs:label "tetrahydrofuranol" ;
rdfs:subClassOf obo:CHEBI_26912 .
obo:UBERON_0009953 a rdfs:Class ;
rdfs:label "post-embryonic organism" ;
rdfs:comment "A multicellular organism that existence_starts_with a post-embryonic stage." ;
rdfs:subClassOf obo:UBERON_0000468 .
obo:CHEBI_2637 a rdfs:Class ;
rdfs:label "amikacin" ;
rdfs:comment "An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group." ;
rdfs:subClassOf obo:CHEBI_22390 , obo:CHEBI_22479 , obo:CHEBI_37622 , obo:CHEBI_47779 , obo:CHEBI_61689 .
obo:GO_0051953 a rdfs:Class ;
rdfs:label "negative regulation of amine transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051051 , obo:GO_0051952 , obo:GO_0065007 .
obo:CHEBI_33674 a rdfs:Class ;
rdfs:label "s-block molecular entity" ;
rdfs:comment "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." ;
rdfs:subClassOf obo:CHEBI_33579 .
obo:GO_0061100 a rdfs:Class ;
rdfs:label "lung neuroendocrine cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0061101 , obo:GO_0061140 .
obo:CHEBI_167164 a rdfs:Class ;
rdfs:label "mineral nutrient" ;
rdfs:comment "A mineral that is an inorganic nutrient which must be ingested and absorbed in adequate amounts to satisfy a wide range of essential metabolic and/or structural functions in the human body." ;
rdfs:subClassOf obo:CHEBI_46662 .
obo:GO_0030033 a rdfs:Class ;
rdfs:label "microvillus assembly" ;
rdfs:comment "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0032528 , obo:GO_0120031 .
obo:CHEBI_64268 a rdfs:Class ;
rdfs:label "erythromycin A(1+)" ;
rdfs:comment "An erythromycin cation that is the conjugate acid of erythromycin A, arising from protonation of the tertiary amino group on the 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl residue; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_64290 .
obo:GO_0072592 a rdfs:Class ;
rdfs:label "oxygen metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving diatomic oxygen (O2)." ;
rdfs:subClassOf obo:GO_0008152 .
obo:PHIPO_0000090 a rdfs:Class ;
rdfs:label "obsolete normal parthenogenesis" .
obo:UBERON_0008397 a rdfs:Class ;
rdfs:label "tracheobronchial epithelium" ;
rdfs:comment "Epithelium pertaining to the trachea and bronchi." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004815 .
obo:GO_0002625 a rdfs:Class ;
rdfs:label "regulation of T cell antigen processing and presentation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002577 , obo:GO_0002709 , obo:GO_0065007 .
obo:GO_0051048 a rdfs:Class ;
rdfs:label "negative regulation of secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ;
rdfs:subClassOf obo:GO_0051046 , obo:GO_0051051 , obo:GO_0065007 .
obo:UBERON_0007828 a rdfs:Class ;
rdfs:label "girdle bone/zone" ;
rdfs:comment "A bone that is part of a appendage girdle region." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0010740 .
obo:GO_0086065 a rdfs:Class ;
rdfs:label "cell communication involved in cardiac conduction" ;
rdfs:comment "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0007154 .
obo:PHIPO_0000543 a rdfs:Class ;
rdfs:label "resistance to teicoplanin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to teicoplanin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_26082 a rdfs:Class ;
rdfs:label "phosphorus molecular entity" ;
rdfs:subClassOf obo:CHEBI_33302 .
obo:GO_1904015 a rdfs:Class ;
rdfs:label "cellular response to serotonin" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_0071868 , obo:GO_1901701 , obo:GO_1904014 .
obo:CL_0002252 a rdfs:Class ;
rdfs:label "epithelial cell of esophagus" ;
rdfs:comment "An epithelial cell of the lining of the esophagus." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002251 .
obo:PHIPO_0000767 a rdfs:Class ;
rdfs:label "sensitive to gentamycin C1"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to gentamycin C1. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000760 .
obo:CHEBI_25608 a rdfs:Class ;
rdfs:label "nucleoside phosphate" ;
rdfs:comment "A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates." ;
rdfs:subClassOf obo:CHEBI_25703 , obo:CHEBI_37734 , obo:CHEBI_61120 .
obo:CL_0011006 a rdfs:Class ;
rdfs:label "Lugaro cell" ;
rdfs:comment "A cerebellar interneuron characterized by a spindle-shaped or triangular soma, parasagittally oriented and located at the border between the granular layer and the Purkinje cell layer. The Lugaro cell extends dendrites predominantly in the parasagittal plane, forming synaptic interactions with basket, stellate, and Golgi cells. Its axonal projections extend upward into the molecular layer, where they form a parasagittal plexus and emit long transverse collaterals that run parallel to the long axis of the cerebellar folia. The Lugaro cell is capable of co-releasing GABA and glycine, as evidenced by the expression of glutamate decarboxylase (GAD65/67) and the glycine transporter GlyT2." ;
rdfs:subClassOf obo:CL_0008059 , obo:CL_4072102 .
obo:CL_0000101 a rdfs:Class ;
rdfs:label "sensory neuron" ;
rdfs:comment "Any neuron having a sensory function; an afferent neuron conveying sensory impulses." ;
rdfs:subClassOf obo:CL_0000526 , obo:CL_0000540 .
obo:GO_0048666 a rdfs:Class ;
rdfs:label "neuron development" ;
rdfs:comment "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:UBERON_0000025 a rdfs:Class ;
rdfs:label "tube" ;
rdfs:comment "Any hollow cylindrical anatomical structure containing a lumen through which substances are transported." ;
rdfs:subClassOf obo:UBERON_0004111 .
obo:GO_0007417 a rdfs:Class ;
rdfs:label "central nervous system development" ;
rdfs:comment "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:PHIPO_0000479 a rdfs:Class ;
rdfs:label "increased size of lipid droplet"@en ;
rdfs:comment "A single organism phenotype observed in the vegetative growth phase of the life cycle in which the size of lipid droplets is increased." ;
rdfs:subClassOf obo:PHIPO_0000036 .
obo:UBERON_0002028 a rdfs:Class ;
rdfs:label "hindbrain" ;
rdfs:comment "The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]." ;
rdfs:subClassOf obo:UBERON_0002616 , obo:UBERON_0004121 .
obo:UBERON_0013694 a rdfs:Class ;
rdfs:label "brain endothelium" ;
rdfs:comment "Vascular endothelium found in blood vessels of the blood-brain-barrier." ;
rdfs:subClassOf obo:UBERON_0001986 .
obo:PHIPO_0000662 a rdfs:Class ;
rdfs:label "resistance to bacitracin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to bacitracin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0071396 a rdfs:Class ;
rdfs:label "cellular response to lipid" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." ;
rdfs:subClassOf obo:GO_0033993 , obo:GO_0070887 .
obo:PHIPO_0001338 a rdfs:Class ;
rdfs:label "sensitive to thiram"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to thiram. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0003609 a rdfs:Class ;
rdfs:label "aorta elastic tissue" ;
rdfs:comment "The dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall." ;
rdfs:subClassOf obo:UBERON_0002521 , obo:UBERON_0003614 .
obo:GO_0120158 a rdfs:Class ;
rdfs:label "positive regulation of collagen catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0010710 , obo:GO_0010714 , obo:GO_0065007 .
obo:CHEBI_140326 a rdfs:Class ;
rdfs:label "tertiary carboxamide" ;
rdfs:comment "A carboxamide resulting from the formal condensation of a carboxylic acid with a secondary amine; formula RC(=O)NHR1R2." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:GO_2000177 a rdfs:Class ;
rdfs:label "regulation of neural precursor cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
a rdfs:Class ;
rdfs:label "Superior olivary complex" ;
rdfs:subClassOf , obo:UBERON_0002128 .
obo:UBERON_0010377 a rdfs:Class ;
rdfs:label "mesenchyme from somatopleure" ;
rdfs:comment "Mesenchyme that develops_from a somatopleure." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005291 , obo:UBERON_0007524 .
obo:CHEBI_60915 a rdfs:Class ;
rdfs:label "diastereoisomeric mixture" ;
rdfs:comment "A mixture composed of two or more diastereoisomers (stereoisomers not related as mirror images)." ;
rdfs:subClassOf obo:CHEBI_60004 .
obo:CHEBI_30103 a rdfs:Class ;
rdfs:label "diazenide" ;
rdfs:subClassOf obo:CHEBI_35106 .
obo:CHEBI_77057 a rdfs:Class ;
rdfs:label "(S)-closantel" ;
rdfs:comment "An N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide that has S configuration." ;
rdfs:subClassOf obo:CHEBI_77054 .
obo:GO_2000471 a rdfs:Class ;
rdfs:label "regulation of hematopoietic stem cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:GO_0051985 a rdfs:Class ;
rdfs:label "negative regulation of chromosome segregation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0051983 , obo:GO_0065007 .
obo:GO_1903351 a rdfs:Class ;
rdfs:label "cellular response to dopamine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_0071870 , obo:GO_1903350 .
obo:UBERON_0000088 a rdfs:Class ;
rdfs:label "trophoblast" ;
rdfs:comment "The mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:PHIPO_0001196 a rdfs:Class ;
rdfs:label "host defense-induced substance level phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, which affects the level of a host produced substance during infection." ;
rdfs:subClassOf obo:PHIPO_0000510 .
obo:GO_0070202 a rdfs:Class ;
rdfs:label "regulation of establishment of protein localization to chromosome" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070201 .
obo:CHEBI_87037 a rdfs:Class ;
rdfs:label "benzimidazole precursor fungicide" ;
rdfs:comment "Compounds based on 1,2-phenylenediamine in which one or both of the primary amino groups have been derivatised so as to permit subsequent benzimidazole formation, and which have been used as fungicides." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:GO_0031032 a rdfs:Class ;
rdfs:label "actomyosin structure organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0030036 .
obo:CL_0011021 a rdfs:Class ;
rdfs:label "fibroblast of upper back skin" ;
rdfs:comment "A fibroblast that is part of upper back skin." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0011022 .
obo:GO_0010662 a rdfs:Class ;
rdfs:label "regulation of striated muscle cell apoptotic process" ;
rdfs:comment "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." ;
rdfs:subClassOf obo:GO_0010660 , obo:GO_0065007 .
obo:GO_1904359 a rdfs:Class ;
rdfs:label "regulation of spore germination" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of spore germination." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0050794 , obo:GO_0065007 .
obo:CHEBI_46787 a rdfs:Class ;
rdfs:label "solvent" ;
rdfs:comment "A substance that dissolves other substances (solutes) to form a solution without any change in their chemical composition." ;
rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_51086 .
obo:GO_1905146 a rdfs:Class ;
rdfs:label "lysosomal protein catabolic process" ;
rdfs:comment "Any cellular protein catabolic process that takes place in a lysosome." ;
rdfs:subClassOf obo:GO_0007039 , obo:GO_0030163 .
obo:GO_0046532 a rdfs:Class ;
rdfs:label "regulation of photoreceptor cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0045664 , obo:GO_0065007 .
obo:GO_0046824 a rdfs:Class ;
rdfs:label "positive regulation of nucleocytoplasmic transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0046822 , obo:GO_0065007 .
obo:UBERON_0000410 a rdfs:Class ;
rdfs:label "bronchial mucosa" ;
rdfs:comment "A mucosa that is part of a bronchus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0004785 .
obo:UBERON_0002166 a rdfs:Class ;
rdfs:label "endocardium of atrium" ;
rdfs:comment "Endocardium that is part of the atrium." ;
rdfs:subClassOf obo:UBERON_0002165 .
obo:PHIPO_0001039 a rdfs:Class ;
rdfs:label "normal cellular toxin level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of toxin measured in a cell is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001038 .
obo:CHEBI_27405 a rdfs:Class ;
rdfs:label "streptidine" ;
rdfs:comment "An amino cyclitol that is scyllo-inositol in which the hydroxy groups at positions 1 and 3 are replaced by guanidino groups." ;
rdfs:subClassOf obo:CHEBI_24436 , obo:CHEBI_61689 .
obo:GO_0048332 a rdfs:Class ;
rdfs:label "mesoderm morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the mesoderm are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048729 .
obo:CHEBI_25414 a rdfs:Class ;
rdfs:label "monoatomic monocation" ;
rdfs:subClassOf obo:CHEBI_23906 .
obo:GO_0002232 a rdfs:Class ;
rdfs:label "leukocyte chemotaxis involved in inflammatory response" ;
rdfs:comment "The movement of an immune cell in response to an external stimulus contributing to an inflammatory response." ;
rdfs:subClassOf obo:GO_0002523 , obo:GO_0030595 .
obo:GO_0090494 a rdfs:Class ;
rdfs:label "dopamine uptake" ;
rdfs:comment "The directed movement of dopamine into a cell." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0090493 .
obo:GO_0090139 a rdfs:Class ;
rdfs:label "mitochondrial chromosome packaging" ;
rdfs:comment "A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure." ;
rdfs:subClassOf obo:GO_0051276 .
obo:GO_2000269 a rdfs:Class ;
rdfs:label "regulation of fibroblast apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of fibroblast apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:GO_0016192 a rdfs:Class ;
rdfs:label "vesicle-mediated transport" ;
rdfs:comment "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 .
obo:UBERON_0005338 a rdfs:Class ;
rdfs:label "outflow tract aortic component" ;
rdfs:comment "An outflow tract that is part of a aorta." ;
rdfs:subClassOf obo:UBERON_0004145 .
obo:UBERON_0007302 a rdfs:Class ;
rdfs:label "pectoral appendage vasculature" ;
rdfs:comment "A vasculature that is part of a pectoral appendage." ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0007304 .
obo:UBERON_0008895 a rdfs:Class ;
rdfs:label "splanchnocranium" ;
rdfs:comment "Subdivision of endoskeleton derived from pharyngeal arches." ;
rdfs:subClassOf obo:UBERON_0011159 .
obo:GO_1902217 a rdfs:Class ;
rdfs:label "erythrocyte apoptotic process" ;
rdfs:comment "Any apoptotic process in an erythrocyte." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0033028 .
obo:UBERON_0009142 a rdfs:Class ;
rdfs:label "entire embryonic mesenchyme" ;
rdfs:comment "Sum total of mesenchyme in the embryo." ;
rdfs:subClassOf obo:UBERON_0000477 .
obo:GO_0007143 a rdfs:Class ;
rdfs:label "female meiotic nuclear division" ;
rdfs:comment "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." ;
rdfs:subClassOf obo:GO_0000280 , obo:GO_0140013 .
obo:GO_1904058 a rdfs:Class ;
rdfs:label "positive regulation of sensory perception of pain" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of sensory perception of pain." ;
rdfs:subClassOf obo:GO_0031646 , obo:GO_0051930 , obo:GO_0065007 .
obo:UBERON_0004357 a rdfs:Class ;
rdfs:label "paired limb/fin bud" ;
rdfs:comment "An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]." ;
rdfs:subClassOf obo:UBERON_0003102 , obo:UBERON_0006598 .
obo:CHEBI_79388 a rdfs:Class ;
rdfs:label "divalent inorganic anion" ;
rdfs:comment "Any inorganic anion with a valency of two." ;
rdfs:subClassOf obo:CHEBI_24834 .
obo:GO_0021743 a rdfs:Class ;
rdfs:label "hypoglossal nucleus development" ;
rdfs:comment "The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048857 .
obo:GO_0046013 a rdfs:Class ;
rdfs:label "regulation of T cell homeostatic proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of resting T cell proliferation." ;
rdfs:subClassOf obo:GO_0042129 , obo:GO_0065007 .
obo:GO_0031969 a rdfs:Class ;
rdfs:label "chloroplast membrane" ;
rdfs:comment "Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope." ;
rdfs:subClassOf obo:GO_0042170 .
obo:CL_4307032 a rdfs:Class ;
rdfs:label "Astro-NT NN_1 Kcnk10 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Agt (Mmus), Prss35 (Mmus), C4b (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Kcnk10, C4b. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5212 Astro-NT NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301589 .
obo:UBERON_0000060 a rdfs:Class ;
rdfs:label "anatomical wall" ;
rdfs:comment "Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:UBERON_0009653 a rdfs:Class ;
rdfs:label "trachea basement membrane" ;
rdfs:comment "A basement membrane that is part of a trachea." ;
rdfs:subClassOf obo:UBERON_0005769 , obo:UBERON_0015329 .
obo:GO_0061182 a rdfs:Class ;
rdfs:label "negative regulation of chondrocyte development" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0032331 , obo:GO_0061181 , obo:GO_0065007 .
obo:GO_1903543 a rdfs:Class ;
rdfs:label "positive regulation of exosomal secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of exosomal secretion." ;
rdfs:subClassOf obo:GO_0044089 , obo:GO_0045921 , obo:GO_0065007 , obo:GO_1903541 .
obo:PHIPO_0000993 a rdfs:Class ;
rdfs:label "obsolete altered RNA level in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of RNA measured in a pathogen or host cell differs from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." .
obo:GO_0097028 a rdfs:Class ;
rdfs:label "dendritic cell differentiation" ;
rdfs:comment "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_1903131 .
obo:GO_1902396 a rdfs:Class ;
rdfs:label "protein localization to bicellular tight junction" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0150105 .
obo:GO_0001743 a rdfs:Class ;
rdfs:label "lens placode formation" ;
rdfs:comment "The initial developmental process that will lead to the formation of an eye." ;
rdfs:subClassOf obo:GO_0048646 , obo:GO_0060788 .
obo:CHEBI_33521 a rdfs:Class ;
rdfs:label "metal atom" ;
rdfs:comment "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:GO_0014910 a rdfs:Class ;
rdfs:label "regulation of smooth muscle cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of smooth muscle cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:GO_2000403 a rdfs:Class ;
rdfs:label "positive regulation of lymphocyte migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lymphocyte migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0071677 , obo:GO_2000401 .
obo:PHIPO_0000011 a rdfs:Class ;
rdfs:label "virulence phenotype" ;
rdfs:comment "A phenotype that is relevant to virulence. Virulence is the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism. (Virulence is observed where pathogenicity is present)." ;
rdfs:subClassOf obo:PHIPO_0001179 .
obo:GO_2001141 a rdfs:Class ;
rdfs:label "regulation of RNA biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010556 , obo:GO_0051252 , obo:GO_0065007 .
obo:PHIPO_0001400 a rdfs:Class ;
rdfs:label "sensitive to flusilazole" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to flusilazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_15355 a rdfs:Class .
obo:GO_0014051 a rdfs:Class ;
rdfs:label "gamma-aminobutyric acid secretion" ;
rdfs:comment "The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues." ;
rdfs:subClassOf obo:GO_0015812 , obo:GO_0046717 , obo:GO_0046903 .
obo:CHEBI_24432 a rdfs:Class ;
rdfs:label "biological role" ;
rdfs:comment "A role played by the molecular entity or part thereof within a biological context." ;
rdfs:subClassOf obo:CHEBI_50906 .
obo:GO_0006937 a rdfs:Class ;
rdfs:label "regulation of muscle contraction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of muscle contraction." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090257 .
obo:GO_0033993 a rdfs:Class ;
rdfs:label "response to lipid" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." ;
rdfs:subClassOf obo:GO_0042221 , obo:GO_0050896 .
obo:PHIPO_0000651 a rdfs:Class ;
rdfs:label "resistance to neomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to neomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000264 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction nuclear transport" ;
rdfs:comment "A pathogen host interaction (cellular process??) phenotype in which nuclear transport is abnormal." .
obo:GO_0120186 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to chromatin" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903828 , obo:GO_1905634 .
obo:CHEBI_87101 a rdfs:Class ;
rdfs:label "triazole antifungal drug" ;
rdfs:comment "Any triazole antifungal agent that has been used for the treatment of fungal infections in humans or animals." ;
rdfs:subClassOf obo:CHEBI_86426 .
obo:GO_0098862 a rdfs:Class ;
rdfs:label "cluster of actin-based cell projections" ;
rdfs:comment "A cell part consisting of multiple, closely packed actin-based cell projections." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0034301 a rdfs:Class ;
rdfs:label "endospore formation" ;
rdfs:comment "The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions." ;
rdfs:subClassOf obo:GO_0043936 .
obo:UBERON_0005979 a rdfs:Class ;
rdfs:label "crista terminalis" ;
rdfs:comment "The vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:PHIPO_0000421 a rdfs:Class ;
rdfs:label "abolished carbohydrate binding"@en ;
rdfs:comment "A single species molecular function phenotype in which carbohydrate binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000419 .
obo:CHEBI_71285 a rdfs:Class ;
rdfs:label "organophosphonate(2-)" ;
rdfs:comment "An organophosphonate oxoanion obtained by deprotonation of both phosphonate OH groups of any phosphonic acid." ;
rdfs:subClassOf obo:CHEBI_59635 .
obo:CHEBI_33704 a rdfs:Class ;
rdfs:label "alpha-amino acid" ;
rdfs:comment "An amino acid in which the amino group is located on the carbon atom at the position α to the carboxy group." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:UBERON_0013126 a rdfs:Class ;
rdfs:label "vein of abdomen" ;
rdfs:comment "A vein that is part of a abdomen." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0003497 .
obo:UBERON_0007010 a rdfs:Class ;
rdfs:label "cleaving embryo" ;
rdfs:comment "Organism at the cleavage stage." ;
rdfs:subClassOf obo:UBERON_0000468 , obo:UBERON_0000922 .
obo:CHEBI_28915 a rdfs:Class ;
rdfs:label "fosfomycin" ;
rdfs:comment "A phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus." ;
rdfs:subClassOf obo:CHEBI_26069 , obo:CHEBI_32955 .
obo:UBERON_0003501 a rdfs:Class ;
rdfs:label "retina blood vessel" ;
rdfs:comment "A blood vessel that is part of a retina [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003496 .
obo:CHEBI_76842 a rdfs:Class ;
rdfs:label "vancomycin(1+)" ;
rdfs:comment "An organic cation that is the conjugate acid of vancomycin, obtained by deprotonation of the carboxy group and protonation of the two amino functions; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 .
obo:GO_0051054 a rdfs:Class ;
rdfs:label "positive regulation of DNA metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." ;
rdfs:subClassOf obo:GO_0010604 , obo:GO_0051052 , obo:GO_0065007 .
obo:GO_1902105 a rdfs:Class ;
rdfs:label "regulation of leukocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of leukocyte differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903706 .
obo:GO_0110020 a rdfs:Class ;
rdfs:label "regulation of actomyosin structure organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin." ;
rdfs:subClassOf obo:GO_0032956 , obo:GO_0065007 .
obo:GO_1901588 a rdfs:Class ;
rdfs:label "dendritic microtubule" ;
rdfs:comment "Any microtubule in a dendrite, a neuron projection." ;
rdfs:subClassOf obo:GO_0005874 .
a rdfs:Class ;
rdfs:label "Cerebral cortex" ;
rdfs:subClassOf , obo:UBERON_0000956 .
obo:GO_2000291 a rdfs:Class ;
rdfs:label "regulation of myoblast proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of myoblast proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:GO_0099642 a rdfs:Class ;
rdfs:label "retrograde axonal protein transport" ;
rdfs:comment "The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0008090 , obo:GO_0099640 .
obo:CHEBI_36834 a rdfs:Class ;
rdfs:label "3-hydroxy steroid" ;
rdfs:comment "Any hydroxy steroid carrying a hydroxy group at position 3." ;
rdfs:subClassOf obo:CHEBI_35350 .
obo:CHEBI_9700 a rdfs:Class ;
rdfs:label "tridemorph" ;
rdfs:comment "A mixture of 4-alkyl-2,6-dimethylmorpholines, where 'alkyl' is a mixture of C11 to C14 homologues of which 60-70% is tridecyl. A systemic fungicide, it is no longer approved for use within the European Union." ;
rdfs:subClassOf obo:CHEBI_60004 , obo:CHEBI_87134 .
obo:UBERON_0003562 a rdfs:Class ;
rdfs:label "midbrain dura mater" ;
rdfs:comment "A dura mater that is part of a midbrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002092 , obo:UBERON_0002363 , obo:UBERON_0003288 .
obo:GO_0005102 a rdfs:Class ;
rdfs:label "signaling receptor binding" ;
rdfs:comment "Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." ;
rdfs:subClassOf obo:GO_0005515 .
obo:GO_0050877 a rdfs:Class ;
rdfs:label "nervous system process" ;
rdfs:comment "An organ system process carried out by any of the organs or tissues of the neurological system." ;
rdfs:subClassOf obo:GO_0003008 .
obo:CHEBI_24271 a rdfs:Class ;
rdfs:label "glucosamines" ;
rdfs:comment "Any hexosamine that is glucose in which at least one of the hydroxy groups has been replaced by an amino group." ;
rdfs:subClassOf obo:CHEBI_24586 .
obo:CHEBI_139512 a rdfs:Class ;
rdfs:label "EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor" ;
rdfs:comment "An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of enoyl-[acyl-carrier-protein] reductase (NADH), EC 1.3.1.9." ;
rdfs:subClassOf obo:CHEBI_76857 .
obo:UBERON_0002330 a rdfs:Class ;
rdfs:label "exocrine system" ;
rdfs:comment "Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:CHEBI_173084 a rdfs:Class ;
rdfs:label "ferroptosis inhibitor" ;
rdfs:comment "Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms." ;
rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 .
obo:CHEBI_46812 a rdfs:Class ;
rdfs:label "1,3-oxazoles" ;
rdfs:subClassOf obo:CHEBI_35790 .
obo:PHIPO_0000145 a rdfs:Class ;
rdfs:label "abnormal DNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is abnormal, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000143 , obo:PHIPO_0000413 .
obo:GO_1903131 a rdfs:Class ;
rdfs:label "mononuclear cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell." ;
rdfs:subClassOf obo:GO_0002521 , obo:GO_0030154 .
obo:GO_0043537 a rdfs:Class ;
rdfs:label "negative regulation of blood vessel endothelial cell migration" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels." ;
rdfs:subClassOf obo:GO_0010596 , obo:GO_0043535 , obo:GO_0065007 .
obo:CL_0000359 a rdfs:Class ;
rdfs:label "vascular associated smooth muscle cell" ;
rdfs:comment "A smooth muscle cell associated with the vasculature." ;
rdfs:subClassOf obo:CL_0000192 , obo:CL_4033054 .
obo:UBERON_0003104 a rdfs:Class ;
rdfs:label "mesenchyme" ;
rdfs:comment "Portion of tissue composed of mesenchymal cells (motile cells that develop from epthelia via an epithelial to mesenchymal transition) and surrounding extracellular material. Mesenchyme has different embryological origins in different metazoan taxa - in many invertebrates it derives in whole or part from ectoderm. In vertebrates it derives largely from mesoderm, and sometimes the terms are used interchangeably, e.g. lateral plate mesoderm/mesenchyme." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:GO_0032946 a rdfs:Class ;
rdfs:label "positive regulation of mononuclear cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation." ;
rdfs:subClassOf obo:GO_0032944 , obo:GO_0065007 , obo:GO_0070665 .
obo:GO_0120277 a rdfs:Class ;
rdfs:label "positive regulation of cerebral blood circulation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cerebral blood circulation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120276 , obo:GO_1903524 .
obo:PATO_0070002 a rdfs:Class ;
rdfs:label "basket cell morphology" ;
rdfs:comment "A cell morphology that inheres in multipolar neurons with densely branched terminal axonal arborizations that form basket-like structures surrounding and synapsing to the somas of target cells." ;
rdfs:subClassOf obo:PATO_0070026 .
obo:UBERON_0003426 a rdfs:Class ;
rdfs:label "dermis adipose tissue" ;
rdfs:comment "An adipose tissue that is part of a dermis [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001013 , obo:UBERON_0003585 .
obo:GO_0032944 a rdfs:Class ;
rdfs:label "regulation of mononuclear cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070663 .
obo:GO_0106215 a rdfs:Class ;
rdfs:label "negative regulation of vesicle fusion with Golgi apparatus" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus." ;
rdfs:subClassOf obo:GO_0031339 , obo:GO_0065007 , obo:GO_0106214 .
obo:GO_0010469 a rdfs:Class ;
rdfs:label "regulation of signaling receptor activity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0065007 , obo:GO_0065009 .
obo:CL_0000149 a rdfs:Class ;
rdfs:label "visual pigment cell" ;
rdfs:subClassOf obo:CL_0000147 .
obo:CHEBI_76812 a rdfs:Class ;
rdfs:label "EC 2.7.11.* (protein-serine/threonine kinase) inhibitor" ;
rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*)." ;
rdfs:subClassOf obo:CHEBI_37699 .
obo:GO_0021565 a rdfs:Class ;
rdfs:label "accessory nerve development" ;
rdfs:comment "The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." ;
rdfs:subClassOf obo:GO_0021545 , obo:GO_0048856 .
obo:PHIPO_0000446 a rdfs:Class ;
rdfs:label "host cell death phenotype"@en ;
rdfs:comment "A single species phenotype that affects the cell death within a host." ;
rdfs:subClassOf obo:PHIPO_0000034 .
obo:CHEBI_29067 a rdfs:Class ;
rdfs:label "carboxylic acid anion" ;
rdfs:comment "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_35406 .
obo:UBERON_0000202 a rdfs:Class ;
rdfs:label "glial blood brain barrier" ;
rdfs:comment "A blood brain barrier composed of glial cells." ;
rdfs:subClassOf obo:UBERON_0000120 .
obo:CL_4310083 a rdfs:Class ;
rdfs:label "GPin-BF Cholinergic GABA GABA-Chol neuron (Primate)" ;
rdfs:comment "A GABA-Chol neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPin-BF Cholinergic GABA." ;
rdfs:subClassOf obo:CL_0008061 .
obo:PHIPO_0001150 a rdfs:Class ;
rdfs:label "abnormal spatial extent of reactive oxygen species production"@en ;
rdfs:comment "A single species localization phenotype in which ROS are produced over a different portion of the cell than normal." ;
rdfs:subClassOf obo:PHIPO_0001094 .
obo:CHEBI_3371 a rdfs:Class ;
rdfs:label "capreomycin" ;
rdfs:subClassOf obo:CHEBI_25903 .
obo:UBERON_0035546 a rdfs:Class ;
rdfs:label "uveal vein" ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:GO_0055057 a rdfs:Class ;
rdfs:label "neuroblast division" ;
rdfs:comment "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." ;
rdfs:subClassOf obo:GO_0051301 .
obo:UBERON_0006340 a rdfs:Class ;
rdfs:label "fourth ventricle choroid plexus stroma" ;
rdfs:comment "A choroid plexus stroma that is part of a fourth ventricle." ;
rdfs:subClassOf obo:UBERON_0005206 .
obo:UBERON_0005660 a rdfs:Class ;
rdfs:label "2nd arch ectoderm" ;
rdfs:comment "An ectoderm that is part of a pharyngeal arch 2." ;
rdfs:subClassOf obo:UBERON_0000924 .
obo:UBERON_0006215 a rdfs:Class ;
rdfs:label "rhombic lip" ;
rdfs:comment "The posterior section of the developing metencephalon recognized transiently within the vertebrate embryo; the rhombic lip extends posteriorly from the roof of the fourth ventricle to dorsal neuroepithelial cell and can be divided into eight structural units based on rhombomeres 1-8 (r1-r8), recognized at early stages of hindbrain development; producing granule cells and five brainstem nuclei, the rhombic lip plays an important role in developing a complex cerebellar neural system." ;
rdfs:subClassOf obo:UBERON_0001048 , obo:UBERON_0006598 .
obo:CHEBI_83057 a rdfs:Class ;
rdfs:label "Daphnia metabolite" ;
rdfs:comment "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" ;
rdfs:subClassOf obo:CHEBI_83039 .
obo:PHIPO_0001389 a rdfs:Class ;
rdfs:label "sensitive to pyrisoxazole" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrisoxazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_77615 a rdfs:Class ;
rdfs:label "terbinafine(1+)" ;
rdfs:comment "An organic cation that is the conjugate acid of terbinafine, obtained by protonation of the amino group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:UBERON_0013756 a rdfs:Class ;
rdfs:label "venous blood" ;
rdfs:comment "A blood that is part of a vein." ;
rdfs:subClassOf obo:UBERON_0000178 .
obo:PATO_0002323 a rdfs:Class ;
rdfs:label "temporal distribution quality" ;
rdfs:comment "A temporal distribution pattern of process occurrences within a regulation/reference process." ;
rdfs:subClassOf obo:PATO_0002062 .
obo:UBERON_0005729 a rdfs:Class ;
rdfs:label "pectoral appendage field" ;
rdfs:comment "A limb/fin field that has the potential to develop into a pectoral appendage bud mesenchyme." ;
rdfs:subClassOf obo:UBERON_0005732 , obo:UBERON_0006598 .
obo:GO_1903701 a rdfs:Class ;
rdfs:label "substantia propria of cornea development" ;
rdfs:comment "The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0034104 a rdfs:Class ;
rdfs:label "negative regulation of tissue remodeling" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling." ;
rdfs:subClassOf obo:GO_0034103 , obo:GO_0051241 , obo:GO_0065007 .
obo:UBERON_0010286 a rdfs:Class ;
rdfs:label "midbrain neural tube" ;
rdfs:comment "Portion of neural tube that gives rise to the midbrain." ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:PHIPO_0000064 a rdfs:Class ;
rdfs:label "asexual spores present"@en ;
rdfs:comment "A reproductive phenotype where asexual spores are present (FAO:0000023). The product of mitosis." ;
rdfs:subClassOf obo:PHIPO_0000080 .
obo:PHIPO_0000448 a rdfs:Class ;
rdfs:label "abnormal number of asexual pathogen spores within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is abnormal" ;
rdfs:subClassOf obo:PHIPO_0000449 .
obo:PHIPO_0001298 a rdfs:Class ;
rdfs:label "normal growth on arborcandin C"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to arborcandin C (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CL_0002177 a rdfs:Class ;
rdfs:label "folliculostellate cell of pars distalis of adenohypophysis" ;
rdfs:comment "A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature." ;
rdfs:subClassOf obo:CL_0000642 , obo:CL_0000710 .
obo:CHEBI_82897 a rdfs:Class ;
rdfs:label "(S)-miconazole" ;
rdfs:comment "A 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that has S) configuration." ;
rdfs:subClassOf obo:CHEBI_82892 .
obo:CL_0001019 a rdfs:Class ;
rdfs:label "CD115-positive monocyte OR common dendritic progenitor" ;
rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1111000)(PMID:19243617)." ;
rdfs:subClassOf obo:CL_0000763 , obo:CL_0002031 .
obo:GO_0035887 a rdfs:Class ;
rdfs:label "aortic smooth muscle cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0035886 .
obo:UBERON_0004638 a rdfs:Class ;
rdfs:label "blood vessel endothelium" ;
rdfs:comment "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0004852 .
obo:CHEBI_76881 a rdfs:Class ;
rdfs:label "EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor" ;
rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*)." ;
rdfs:subClassOf obo:CHEBI_76668 .
obo:CHEBI_83707 a rdfs:Class ;
rdfs:label "1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol" ;
rdfs:comment "A tertiary alcohol that is ethanol in which one of the hydrogens at position 1 is replaced by an p-fluorophenyl group, the other hydrogen at position 1 is replaced by a p-fluorophenyl group, and one of the hydrogens at position 2 is replaced by a 1H-1,2,4-triazol-1-yl group." ;
rdfs:subClassOf obo:CHEBI_26878 , obo:CHEBI_35727 , obo:CHEBI_83575 .
obo:GO_0042069 a rdfs:Class ;
rdfs:label "regulation of catecholamine metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." ;
rdfs:subClassOf obo:GO_0033238 , obo:GO_0065007 , obo:GO_0080090 .
obo:GO_1905505 a rdfs:Class ;
rdfs:label "positive regulation of motile cilium assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of motile cilium assembly." ;
rdfs:subClassOf obo:GO_0045724 , obo:GO_0065007 , obo:GO_1905503 .
obo:GO_0045445 a rdfs:Class ;
rdfs:label "myoblast differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0043932 a rdfs:Class ;
rdfs:label "ossification involved in bone remodeling" ;
rdfs:comment "The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli." ;
rdfs:subClassOf obo:GO_0001503 .
obo:GO_0043412 a rdfs:Class ;
rdfs:label "macromolecule modification" ;
rdfs:comment "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." ;
rdfs:subClassOf obo:GO_0043170 .
obo:UBERON_0000071 a rdfs:Class ;
rdfs:label "death stage" ;
rdfs:comment "End of the life of an organism." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:RO_0002229 a rdf:Property ;
rdfs:label "ends"@en ;
rdfs:comment "inverse of ends with" ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000050 .
obo:GO_1903781 a rdfs:Class ;
rdfs:label "positive regulation of cardiac conduction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac conduction." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0065007 , obo:GO_1903779 .
obo:GO_0021606 a rdfs:Class ;
rdfs:label "accessory nerve maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." ;
rdfs:subClassOf obo:GO_0021605 , obo:GO_0021700 .
obo:PHIPO_0000745 a rdfs:Class ;
rdfs:label "sensitive to neomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to neomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0032988 a rdfs:Class ;
rdfs:label "protein-RNA complex disassembly" ;
rdfs:comment "The disaggregation of a protein-RNA complex into its constituent components." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0032984 , obo:GO_0071826 .
obo:PHIPO_0000626 a rdfs:Class ;
rdfs:label "resistance to prothionamide"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to prothionamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_2000173 a rdfs:Class ;
rdfs:label "negative regulation of branching morphogenesis of a nerve" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_2000172 .
obo:GO_0098974 a rdfs:Class ;
rdfs:label "postsynaptic actin cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0030036 , obo:GO_0099188 .
obo:UBERON_0003115 a rdfs:Class ;
rdfs:label "pharyngeal arch 4" ;
rdfs:comment "Contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus." ;
rdfs:subClassOf obo:UBERON_0002539 .
obo:GO_0014887 a rdfs:Class ;
rdfs:label "cardiac muscle adaptation" ;
rdfs:comment "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." ;
rdfs:subClassOf obo:GO_0014888 , obo:GO_0043500 .
obo:UBERON_0004035 a rdfs:Class ;
rdfs:label "cortical subplate" ;
rdfs:comment "The transient outer neural tube region that contains the first generated post-mitotic neurons that receive synaptic input from thalamic axons and in turn project axons to the developing cortical plate." ;
rdfs:subClassOf obo:UBERON_0014950 .
obo:UBERON_0003429 a rdfs:Class ;
rdfs:label "abdomen nerve" ;
rdfs:comment "A nerve that is part of an abdomen [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001021 , obo:UBERON_0003825 .
obo:UBERON_0004785 a rdfs:Class ;
rdfs:label "respiratory system mucosa" ;
rdfs:comment "The mucous membrane lining the respiratory tract." ;
rdfs:subClassOf obo:UBERON_0000344 .
obo:UBERON_0009715 a rdfs:Class ;
rdfs:label "stomodeal lumen" ;
rdfs:comment "An anatomical cavity that surrounded_by a stomodeum." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0002699 a rdfs:Class ;
rdfs:label "positive regulation of immune effector process" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of an immune effector process." ;
rdfs:subClassOf obo:GO_0002684 , obo:GO_0002697 , obo:GO_0065007 .
obo:GO_0050794 a rdfs:Class ;
rdfs:label "regulation of cellular process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:CL_0000000 a rdfs:Class ;
rdfs:label "cell" ;
rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
rdfs:subClassOf obo:CARO_0000000 , obo:UBERON_0000061 , obo:UBERON_0000465 .
obo:GO_0030212 a rdfs:Class ;
rdfs:label "hyaluronan metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0030203 .
obo:GO_1903950 a rdfs:Class ;
rdfs:label "negative regulation of AV node cell action potential" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential." ;
rdfs:subClassOf obo:GO_0045759 , obo:GO_0065007 , obo:GO_0098904 .
obo:GO_0043386 a rdfs:Class ;
rdfs:label "mycotoxin biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus." ;
rdfs:subClassOf obo:GO_0009403 , obo:GO_0043385 .
obo:GO_0002250 a rdfs:Class ;
rdfs:label "adaptive immune response" ;
rdfs:comment "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." ;
rdfs:subClassOf obo:GO_0006955 .
obo:CL_0000864 a rdfs:Class ;
rdfs:label "tissue-resident macrophage" ;
rdfs:comment "A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." ;
rdfs:subClassOf obo:CL_0000235 .
obo:CHEBI_87185 a rdfs:Class ;
rdfs:label "florfenicol" ;
rdfs:comment "A carboxamide that is the N-dichloroacetyl derivative of (1R,2S)-2-amino-3-fluoro-1-[4-(methanesulfonyl)phenyl]propan-1-ol. A synthetic veterinary antibiotic that is used for treatment of bovine respiratory disease and foot rot; also used in aquaculture." ;
rdfs:subClassOf obo:CHEBI_140325 , obo:CHEBI_33552 , obo:CHEBI_35681 , obo:CHEBI_35850 , obo:CHEBI_36683 , obo:CHEBI_37143 .
obo:PHIPO_0001258 a rdfs:Class ;
rdfs:label "decreased expression of a host defense-related protein involved in a pathogen interaction"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host defense-related protein usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001257 .
obo:GO_0170037 a rdfs:Class ;
rdfs:label "export from the mitochondrion" ;
rdfs:comment "The directed movement of substances from the mitochondrion to the cytosol." ;
rdfs:subClassOf obo:GO_0010496 , obo:GO_0046907 , obo:GO_1990542 .
obo:GO_0016798 a rdfs:Class ;
rdfs:label "hydrolase activity, acting on glycosyl bonds" ;
rdfs:comment "Catalysis of the hydrolysis of any glycosyl bond." ;
rdfs:subClassOf obo:GO_0016787 .
obo:GO_0032253 a rdfs:Class ;
rdfs:label "dense core granule localization" ;
rdfs:comment "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell." ;
rdfs:subClassOf obo:GO_0032252 , obo:GO_0051179 .
obo:PHIPO_0000756 a rdfs:Class ;
rdfs:label "sensitive to resveratrol"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to resveratrol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_51151 a rdfs:Class ;
rdfs:label "dipolar compound" ;
rdfs:comment "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." ;
rdfs:subClassOf obo:CHEBI_72695 .
obo:CL_4033093 a rdfs:Class ;
rdfs:label "limbal epithelial stem cell of cornea" ;
rdfs:comment "A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023)." ;
rdfs:subClassOf obo:CL_0000034 , obo:CL_0000036 .
obo:GO_1902251 a rdfs:Class ;
rdfs:label "negative regulation of erythrocyte apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process." ;
rdfs:subClassOf obo:GO_0033033 , obo:GO_0065007 , obo:GO_1902250 .
obo:CHEBI_6030 a rdfs:Class ;
rdfs:label "isoniazide" ;
rdfs:comment "A carbohydrazide obtained by formal condensation between pyridine-4-carboxylic acid and hydrazine." ;
rdfs:subClassOf obo:CHEBI_26420 , obo:CHEBI_35363 .
obo:CHEBI_24583 a rdfs:Class ;
rdfs:label "hexitol" ;
rdfs:subClassOf obo:CHEBI_17522 .
obo:CHEBI_25696 a rdfs:Class ;
rdfs:label "organic anion" ;
rdfs:comment "Any organic ion with a net negative charge." ;
rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_25699 .
obo:GO_0021985 a rdfs:Class ;
rdfs:label "neurohypophysis development" ;
rdfs:comment "The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation." ;
rdfs:subClassOf obo:GO_0048732 , obo:GO_0048856 .
obo:GO_2000833 a rdfs:Class ;
rdfs:label "positive regulation of steroid hormone secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of steroid hormone secretion." ;
rdfs:subClassOf obo:GO_0032370 , obo:GO_0046887 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_2000831 .
obo:GO_1905167 a rdfs:Class ;
rdfs:label "positive regulation of lysosomal protein catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904352 , obo:GO_1905165 .
obo:GO_0033044 a rdfs:Class ;
rdfs:label "regulation of chromosome organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:UBERON_0001530 a rdfs:Class ;
rdfs:label "common carotid artery plus branches" ;
rdfs:comment "A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm]." ;
rdfs:subClassOf obo:UBERON_0004573 .
obo:CHEBI_16247 a rdfs:Class ;
rdfs:label "phospholipid" ;
rdfs:comment "A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides." ;
rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_25703 , obo:CHEBI_37734 .
obo:GO_0015932 a rdfs:Class ;
rdfs:label "nucleobase-containing compound transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 .
obo:UBERON_0034875 a rdfs:Class ;
rdfs:label "future pituitary gland" ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:UBERON_0003351 a rdfs:Class ;
rdfs:label "pharyngeal epithelium" ;
rdfs:comment "An epithelium that is part of a pharynx [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003929 , obo:UBERON_0004807 , obo:UBERON_0005911 .
obo:UBERON_0000375 a rdfs:Class ;
rdfs:label "mandibular nerve" ;
rdfs:comment "The motor and sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the auricle, the external acoustic meatus, tympanic membrane, temporal region, the cheek, the skin overlying the mandible, the anterior portion of the tongue, the floor of the mouth, lower teeth and gingiva and transmits motor information from the muscles of mastication, the mylohyoid muscle and digastric muscle and the muscles tensor tympani and tensor veli palatini." ;
rdfs:subClassOf obo:UBERON_0011779 .
obo:PHIPO_0000055 a rdfs:Class ;
rdfs:label "delayed sexual sporulation"@en ;
rdfs:comment "A reproductive phenotype in which the occurrence of sexual spore formation happens later than normal." ;
rdfs:subClassOf obo:PHIPO_0000077 .
obo:CL_0000467 a rdfs:Class ;
rdfs:label "adrenocorticotropic hormone secreting cell" ;
rdfs:comment "A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000167 .
obo:CL_2000032 a rdfs:Class ;
rdfs:label "peripheral nervous system neuron" ;
rdfs:comment "A neuron that is part of a peripheral nervous system." ;
rdfs:subClassOf obo:CL_0000540 .
obo:UBERON_0000991 a rdfs:Class ;
rdfs:label "gonad" ;
rdfs:comment "Reproductive organ that produces and releases eggs (ovary) or sperm (testis)." ;
rdfs:subClassOf obo:UBERON_0003133 .
obo:BFO_0000067 a rdf:Property ;
rdfs:label "contains process"@en ;
rdfs:comment "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
rdfs:range .
obo:CHEBI_25704 a rdfs:Class ;
rdfs:label "organic sulfate" ;
rdfs:comment "Compounds of the general formula SO3HOR where R is an organyl group" ;
rdfs:subClassOf obo:CHEBI_26820 .
obo:CHEBI_141498 a rdfs:Class ;
rdfs:label "hemiaminal ether" ;
rdfs:comment "An organic amino compound that is a hemiaminal in which the hydrogen atom of the hydroxy group has been replaced by an organyl group. General formula: R2C(OR')NR2 ( R ≠ H ). Also known as α-amino ethers." ;
rdfs:subClassOf obo:CHEBI_36963 , obo:CHEBI_50047 .
obo:UBERON_0010213 a rdfs:Class ;
rdfs:label "laryngeal pre-cartilage condensation" ;
rdfs:subClassOf obo:UBERON_0005866 .
obo:UBERON_0002324 a rdfs:Class ;
rdfs:label "muscle of back" ;
rdfs:comment "Any muscle organ that is part of a back [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001774 , obo:UBERON_0005174 , obo:UBERON_0014892 .
obo:UBERON_0003849 a rdfs:Class ;
rdfs:label "mesencephalic neural crest" ;
rdfs:comment "A neural crest that has_potential_to_developmentally_contribute_to a midbrain." ;
rdfs:subClassOf obo:UBERON_0002342 , obo:UBERON_0003099 .
obo:UBERON_0012180 a rdfs:Class ;
rdfs:label "head or neck skin" ;
rdfs:comment "A zone of skin that is part of a craniocervical region." ;
rdfs:subClassOf obo:UBERON_0000014 .
obo:PATO_0002266 a rdfs:Class ;
rdfs:label "3-D shape" ;
rdfs:comment "A shape that inheres in a 3 dimensional entity." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:PATO_0040072 a rdfs:Class ;
rdfs:label "high nuclear/cytoplasmic ratio" ;
rdfs:comment "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." ;
rdfs:subClassOf obo:PATO_0001396 .
obo:PHIPO_0001237 a rdfs:Class ;
rdfs:label "effector-mediated suppression of host PAMP-triggered immunity absent"@en ;
rdfs:comment "A cell signaling pathway phenotype where the molecular pattern-induced host innate immune response signaling pathway is not suppressed by a pathogen. (GO:0052034)" ;
rdfs:subClassOf obo:PHIPO_0001176 .
obo:UBERON_0002979 a rdfs:Class ;
rdfs:label "Purkinje cell layer of cerebellar cortex" ;
rdfs:comment "The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." ;
rdfs:subClassOf obo:UBERON_0004130 .
obo:BSPO_0015014 a rdf:Property ;
rdfs:range .
obo:GO_0099174 a rdfs:Class ;
rdfs:label "regulation of presynapse organization" ;
rdfs:comment "Any process that modulates the physical form of a presynapse." ;
rdfs:subClassOf obo:GO_0050807 , obo:GO_0065007 .
obo:CL_0000127 a rdfs:Class ;
rdfs:label "astrocyte" ;
rdfs:comment "A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury." ;
rdfs:subClassOf obo:CL_0000126 .
obo:UBERON_0013136 a rdfs:Class ;
rdfs:label "vein of lip" ;
rdfs:comment "A vein that drains a lip." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:GO_2000155 a rdfs:Class ;
rdfs:label "positive regulation of cilium-dependent cell motility" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902019 , obo:GO_2000147 .
obo:PHIPO_0001218 a rdfs:Class ;
rdfs:label "chemical phenotype"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity, resistance or absence of change of individuals or populations after exposure to a specific chemical." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:GO_0002067 a rdfs:Class ;
rdfs:label "glandular epithelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." ;
rdfs:subClassOf obo:GO_0002065 , obo:GO_0030154 .
obo:GO_0048477 a rdfs:Class ;
rdfs:label "oogenesis" ;
rdfs:comment "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0007281 , obo:GO_0007292 , obo:GO_0048468 .
obo:PHIPO_0000191 a rdfs:Class ;
rdfs:label "obsolete decreased pathogen host interaction DNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:UBERON_0003126 a rdfs:Class ;
rdfs:label "trachea" ;
rdfs:comment "The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]." ;
rdfs:subClassOf obo:UBERON_0000117 .
obo:UBERON_0009603 a rdfs:Class ;
rdfs:label "right lung associated mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a developing right lung." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0004883 .
obo:GO_0031982 a rdfs:Class ;
rdfs:label "vesicle" ;
rdfs:comment "Any small, fluid-filled, spherical organelle enclosed by membrane." ;
rdfs:subClassOf obo:GO_0043227 .
obo:UBERON_0010323 a rdfs:Class ;
rdfs:label "cranial skeletal system" ;
rdfs:comment "Skeletal subdivision of the head including skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:GO_0110053 a rdfs:Class ;
rdfs:label "regulation of actin filament organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of actin filament organization." ;
rdfs:subClassOf obo:GO_0032956 , obo:GO_0065007 , obo:GO_1902903 .
obo:CL_1001609 a rdfs:Class ;
rdfs:label "muscle fibroblast" ;
rdfs:comment "Fibroblast from muscle organ." ;
rdfs:subClassOf obo:CL_0000057 .
obo:PATO_0002147 a rdfs:Class ;
rdfs:label "reduced virulence" ;
rdfs:comment "A virulence that is relatively low." ;
rdfs:subClassOf obo:PATO_0002146 , obo:PATO_0002303 .
obo:CHEBI_43254 a rdfs:Class ;
rdfs:label "(4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one" ;
rdfs:subClassOf obo:CHEBI_38337 .
obo:GO_0046716 a rdfs:Class ;
rdfs:label "muscle cell cellular homeostasis" ;
rdfs:comment "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state." ;
rdfs:subClassOf obo:GO_0019725 .
obo:GO_0010632 a rdfs:Class ;
rdfs:label "regulation of epithelial cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of epithelial cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0051239 , obo:GO_0065007 .
obo:PHIPO_0001099 a rdfs:Class ;
rdfs:label "obsolete increased RNA level in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of RNA measured in a pathogen or host cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." .
obo:GO_0046785 a rdfs:Class ;
rdfs:label "microtubule polymerization" ;
rdfs:comment "The addition of tubulin heterodimers to one or both ends of a microtubule." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0031109 , obo:GO_0051258 , obo:GO_0097435 .
obo:UBERON_8000006 a rdfs:Class ;
rdfs:label "left side of back" ;
rdfs:comment "Left part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane." ;
rdfs:subClassOf obo:UBERON_0001137 , obo:UBERON_0015212 .
obo:GO_1905453 a rdfs:Class ;
rdfs:label "regulation of myeloid progenitor cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901532 .
obo:CHEBI_21638 a rdfs:Class ;
rdfs:label "N-acylglucosamine" ;
rdfs:subClassOf obo:CHEBI_21656 , obo:CHEBI_24271 .
obo:CHEBI_26020 a rdfs:Class ;
rdfs:label "phosphate" ;
rdfs:comment "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." ;
rdfs:subClassOf obo:CHEBI_26079 .
obo:PATO_0001651 a rdfs:Class ;
rdfs:label "decreased resistance to" ;
rdfs:comment "A resistance to a stimulus which is relatively low." ;
rdfs:subClassOf obo:PATO_0001178 , obo:PATO_0002303 .
obo:UBERON_0004063 a rdfs:Class ;
rdfs:label "spinal cord alar plate" ;
rdfs:comment "The region of the mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses; the alar plate develops into the dorsal horn in the grey matter of the spinal cord." ;
rdfs:subClassOf obo:UBERON_0005882 .
obo:CHEBI_3504 a rdfs:Class ;
rdfs:label "cefpodoxime" ;
rdfs:comment "A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis." ;
rdfs:subClassOf obo:CHEBI_23066 , obo:CHEBI_33575 .
obo:PHIPO_0001083 a rdfs:Class ;
rdfs:label "host defense-induced callose deposition present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host produced callose deposition usually present during infection is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:GO_0060922 a rdfs:Class ;
rdfs:label "atrioventricular node cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node." ;
rdfs:subClassOf obo:GO_0003292 , obo:GO_0030154 , obo:GO_0060920 .
obo:CL_0000206 a rdfs:Class ;
rdfs:label "chemoreceptor cell" ;
rdfs:comment "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood." ;
rdfs:subClassOf obo:CL_0000197 .
obo:PHIPO_0000075 a rdfs:Class ;
rdfs:label "abnormal asexual spore shape"@en ;
rdfs:comment "A reproductive morphology phenotype where the shape of the asexual spore is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000127 .
obo:GO_0099188 a rdfs:Class ;
rdfs:label "postsynaptic cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton." ;
rdfs:subClassOf obo:GO_0007010 , obo:GO_0016043 .
obo:PHIPO_0000862 a rdfs:Class ;
rdfs:label "sensitive to ceftazidime"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ceftazidime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1903567 a rdfs:Class ;
rdfs:label "regulation of protein localization to ciliary membrane" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903564 , obo:GO_1904375 , obo:GO_1905475 .
obo:UBERON_0004464 a rdfs:Class ;
rdfs:label "musculature of thorax" ;
rdfs:comment "Any collection of muscles that is part of a thorax [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001015 , obo:UBERON_0004479 .
obo:GO_0046830 a rdfs:Class ;
rdfs:label "positive regulation of RNA import into nucleus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus." ;
rdfs:subClassOf obo:GO_0032241 , obo:GO_0046824 , obo:GO_0046828 , obo:GO_0065007 .
obo:UBERON_0019207 a rdfs:Class ;
rdfs:label "chorioretinal region" ;
rdfs:comment "The part of the eye that consists of both the retina and the optic choroid." ;
rdfs:subClassOf obo:UBERON_0000481 .
obo:GO_0035910 a rdfs:Class ;
rdfs:label "ascending aorta morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." ;
rdfs:subClassOf obo:GO_0009653 .
obo:UBERON_0036658 a rdfs:Class ;
rdfs:label "wall of central canal of spinal cord" ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0005358 .
obo:UBERON_0001484 a rdfs:Class ;
rdfs:label "articular capsule" ;
rdfs:comment "An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0000094 .
obo:PHIPO_0000435 a rdfs:Class ;
rdfs:label "abolished catalytic activity"@en ;
rdfs:comment "A single species molecular function phenotype in which a specified catalytic activity is absent." ;
rdfs:subClassOf obo:PHIPO_0000434 .
obo:CHEBI_39442 a rdfs:Class ;
rdfs:label "fluorescent probe" ;
rdfs:comment "A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy." ;
rdfs:subClassOf obo:CHEBI_50406 .
obo:PHIPO_0000778 a rdfs:Class ;
rdfs:label "sensitive to eflornithine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to eflornithine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0002399 a rdfs:Class ;
rdfs:label "MHC class II protein complex assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex." ;
rdfs:subClassOf obo:GO_0002396 , obo:GO_0022607 .
obo:GO_1904948 a rdfs:Class ;
rdfs:label "midbrain dopaminergic neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron." ;
rdfs:subClassOf obo:GO_0021953 , obo:GO_0030154 , obo:GO_0071542 .
obo:GO_0003131 a rdfs:Class ;
rdfs:label "mesodermal-endodermal cell signaling" ;
rdfs:comment "Any process that mediates the transfer of information from mesodermal cells to endodermal cells." ;
rdfs:subClassOf obo:GO_0007267 .
obo:PATO_0001908 a rdfs:Class ;
rdfs:label "multinucleate" ;
rdfs:comment "A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus." ;
rdfs:subClassOf obo:PATO_0002505 .
obo:CL_2000005 a rdfs:Class ;
rdfs:label "brain macroglial cell" ;
rdfs:comment "Any macroglial cell that is part of a brain." ;
rdfs:subClassOf obo:CL_0000126 .
obo:GO_0098901 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle cell action potential" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0098900 .
obo:UBERON_0010347 a rdfs:Class ;
rdfs:label "6th arch mesenchyme from head mesenchyme" ;
rdfs:comment "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0010031 , obo:UBERON_0010360 .
obo:GO_0045814 a rdfs:Class ;
rdfs:label "negative regulation of gene expression, epigenetic" ;
rdfs:comment "An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation." ;
rdfs:subClassOf obo:GO_0010629 , obo:GO_0040029 .
obo:CHEBI_35238 a rdfs:Class ;
rdfs:label "amino-acid zwitterion" ;
rdfs:comment "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:UBERON_0004024 a rdfs:Class ;
rdfs:label "medial ganglionic eminence" ;
rdfs:comment "A distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the neocortex; however, hippocampal neurons, thalamus, septum and olfactory bulb neurons are also partly derived from the MGE." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0017046 a rdfs:Class ;
rdfs:label "peptide hormone binding" ;
rdfs:comment "Binding to a peptide with hormonal activity in animals." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0042562 .
obo:GO_0089704 a rdfs:Class ;
rdfs:label "L-glutamate transmembrane export from vacuole" ;
rdfs:comment "The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane." ;
rdfs:subClassOf obo:GO_0015813 , obo:GO_0032974 , obo:GO_0055085 .
obo:GO_0120255 a rdfs:Class ;
rdfs:label "olefinic compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0120254 .
obo:PATO_0002014 a rdfs:Class ;
rdfs:label "structure, cavities" ;
rdfs:comment "A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:CHEBI_87207 a rdfs:Class ;
rdfs:label "pyrimidine fungicide" ;
rdfs:comment "Any pyrimidine antifungal agent that has been used as a fungicide." ;
rdfs:subClassOf obo:CHEBI_87204 .
obo:PHIPO_0000796 a rdfs:Class ;
rdfs:label "sensitive to tunicamycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tunicamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0011861 a rdfs:Class ;
rdfs:label "aorta collagen fibril" ;
rdfs:comment "The connective tissue bundles in the extracellular matrix of aorta tissue that are composed of collagen, and play a role in tissue strength and elasticity." ;
rdfs:subClassOf obo:UBERON_0011860 .
obo:GO_0006897 a rdfs:Class ;
rdfs:label "endocytosis" ;
rdfs:comment "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." ;
rdfs:subClassOf obo:GO_0016192 , obo:GO_0098657 .
obo:CL_0017500 a rdfs:Class ;
rdfs:label "neutrophillic cytoplasm" ;
rdfs:comment "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain." ;
rdfs:subClassOf obo:GO_0005737 .
obo:CL_0002397 a rdfs:Class ;
rdfs:label "CD14-positive, CD16-positive monocyte" ;
rdfs:comment "A CD14-positive monocyte that is also CD16-positive and CCR2-negative." ;
rdfs:subClassOf obo:CL_0001054 .
obo:UBERON_8600018 a rdfs:Class ;
rdfs:label "neuroendocrine system" ;
rdfs:comment "A regulatory system of the body that integrates the nervous system and the endocrine system. This system is formed by specialized neuroendocrine cells located mainly in the nervous system and neuroendocrine glands. However, they can also be found as either single cells or small clusters of cells dispersed throughout the surface epithelium of different tissues. The neuroendocrine system functions through the release of neurotransmitters and neurohormones, enabling communication between the endocrine and nervous systems to govern vitally important processes that include growth, reproduction, metabolism and energy homeostasis, electrolyte and water balance, and responses to stress." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:UBERON_0036294 a rdfs:Class ;
rdfs:label "mucosa of lip" ;
rdfs:comment "A mucosa that is part of a lip region [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0003729 .
obo:PHIPO_0001405 a rdfs:Class ;
rdfs:label "resistance to dimethomorph" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to dimethomorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0022407 a rdfs:Class ;
rdfs:label "regulation of cell-cell adhesion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." ;
rdfs:subClassOf obo:GO_0030155 , obo:GO_0065007 .
obo:GO_0045778 a rdfs:Class ;
rdfs:label "positive regulation of ossification" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." ;
rdfs:subClassOf obo:GO_0030278 , obo:GO_0051240 , obo:GO_0065007 .
obo:UBERON_0013162 a rdfs:Class ;
rdfs:label "right lateral ventricle" ;
rdfs:comment "A telencephalic ventricle that is in_the_right_side_of a telencephalon." ;
rdfs:subClassOf obo:UBERON_0002285 , obo:UBERON_0015212 .
obo:UBERON_0010188 a rdfs:Class ;
rdfs:label "protuberance" ;
rdfs:comment "A roughly circular bulge in a surface." ;
rdfs:subClassOf obo:UBERON_0034944 .
obo:UBERON_0010243 a rdfs:Class ;
rdfs:label "merocrine gland" ;
rdfs:comment "An exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged." ;
rdfs:subClassOf obo:UBERON_0002365 .
obo:GO_0021636 a rdfs:Class ;
rdfs:label "trigeminal nerve morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0021602 .
obo:GO_1901862 a rdfs:Class ;
rdfs:label "negative regulation of muscle tissue development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0065007 , obo:GO_1901861 .
obo:GO_0002027 a rdfs:Class ;
rdfs:label "regulation of heart rate" ;
rdfs:comment "Any process that modulates the frequency or rate of heart contraction." ;
rdfs:subClassOf obo:GO_0008016 , obo:GO_0065008 .
obo:UBERON_0006682 a rdfs:Class ;
rdfs:label "hypoglossal canal" ;
rdfs:comment "The hypoglossal canal is a bony canal in the occipital bone of the skull." ;
rdfs:subClassOf obo:UBERON_0004111 , obo:UBERON_0013685 .
obo:UBERON_0004695 a rdfs:Class ;
rdfs:label "arterial system smooth muscle" ;
rdfs:comment "A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 .
obo:PHIPO_0001179 a rdfs:Class ;
rdfs:label "infective ability phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype that affects the infective ability of a pathogen during attempted colonization of a host." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:PHIPO_0000629 a rdfs:Class ;
rdfs:label "resistance to colistin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to colistin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0004133 a rdfs:Class ;
rdfs:label "salivatory nucleus" ;
rdfs:comment "Missing definition for term UBERON:0004133. Please replace it using linked reference." ;
rdfs:subClassOf obo:UBERON_0006331 , obo:UBERON_0009662 .
obo:CHEBI_83758 a rdfs:Class ;
rdfs:label "1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole" ;
rdfs:comment "An epoxide that is oxirane substituted by a 2-chlorophenyl, 4-fluorophenyl and a 1H-1,2,4-triazol-1-ylmethyl groups." ;
rdfs:subClassOf obo:CHEBI_32955 , obo:CHEBI_35727 , obo:CHEBI_83403 , obo:CHEBI_83575 .
obo:CL_4307035 a rdfs:Class ;
rdfs:label "Astro-NT NN_2 Sez6l astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Otx2 (Mmus), Unc13c (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Sez6l, Unc13c. These cells are located in the Thalamus , in or close to the regions: Posterior complex of the thalamus, Ventral posteromedial nucleus of the thalamus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5215 Astro-NT NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301590 .
obo:GO_0051971 a rdfs:Class ;
rdfs:label "positive regulation of transmission of nerve impulse" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." ;
rdfs:subClassOf obo:GO_0010647 , obo:GO_0031646 , obo:GO_0051969 , obo:GO_0065007 .
obo:CHEBI_71415 a rdfs:Class ;
rdfs:label "nitrofurantoin" ;
rdfs:comment "An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA." ;
rdfs:subClassOf obo:CHEBI_24628 , obo:CHEBI_87230 .
obo:CL_0000048 a rdfs:Class ;
rdfs:label "multi fate stem cell" ;
rdfs:comment "A stem cell that can give rise to multiple lineages of cells." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000034 .
obo:GO_0044292 a rdfs:Class ;
rdfs:label "dendrite terminus" ;
rdfs:comment "A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0002456 a rdfs:Class ;
rdfs:label "T cell mediated immunity" ;
rdfs:comment "Any process involved in the carrying out of an immune response by a T cell." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0002449 , obo:GO_0002460 .
a rdfs:Class ;
rdfs:label "Islands of Calleja" ;
rdfs:subClassOf , obo:UBERON_0001881 .
obo:UBERON_0001592 a rdfs:Class ;
rdfs:label "bronchial vein" ;
rdfs:comment "The bronchial veins are small vessels that return blood from the larger bronchi and structures at the roots of the lungs. The right side drains into the azygos vein, while the left side drains into the left superior intercostal vein or the accessory hemiazygos vein. The bronchial veins are counterparts to the bronchial arteries. The veins, however, do not return all of the blood supplied by the arteries; much of the blood that is carried in the bronchial arteries is returned to the heart via the pulmonary veins. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:CHEBI_46895 a rdfs:Class ;
rdfs:label "lipopeptide" ;
rdfs:comment "A compound consisting of a peptide with attached lipid." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_18059 .
obo:GO_0007611 a rdfs:Class ;
rdfs:label "learning or memory" ;
rdfs:comment "The acquisition and processing of information and/or the storage and retrieval of this information over time." ;
rdfs:subClassOf obo:GO_0007610 , obo:GO_0050890 .
obo:GO_0030017 a rdfs:Class ;
rdfs:label "sarcomere" ;
rdfs:comment "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_50584 a rdfs:Class ;
rdfs:label "alkyl alcohol" ;
rdfs:comment "An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position." ;
rdfs:subClassOf obo:CHEBI_2571 .
obo:GO_0060533 a rdfs:Class ;
rdfs:label "bronchus cartilage morphogenesis" ;
rdfs:comment "The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060536 .
obo:PHIPO_0001078 a rdfs:Class ;
rdfs:label "absence of cellular melanin accumulation"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of melanin in a cell is absent." ;
rdfs:subClassOf obo:PHIPO_0001077 .
obo:UBERON_0003064 a rdfs:Class ;
rdfs:label "intermediate mesoderm" ;
rdfs:comment "The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:PATO_0045049 a rdfs:Class ;
rdfs:label "normal sensitivity toward" ;
rdfs:comment "A sensitivity toward an external stimulus which is relatively normal or average" ;
rdfs:subClassOf obo:PATO_0000516 , obo:PATO_0045001 .
obo:CHEBI_33700 a rdfs:Class ;
rdfs:label "proteinogenic amino-acid residue" ;
rdfs:subClassOf obo:CHEBI_33710 .
a rdf:Property ;
rdfs:range .
obo:GO_0048845 a rdfs:Class ;
rdfs:label "venous blood vessel morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048514 .
obo:GO_0060460 a rdfs:Class ;
rdfs:label "left lung morphogenesis" ;
rdfs:comment "The process in which anatomical structures of the left lung are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060425 .
obo:PHIPO_0001288 a rdfs:Class ;
rdfs:label "resistance to tolnaftate"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tolnaftate. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000526 a rdfs:Class ;
rdfs:label "resistance to carbenicillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to carbenicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:GO_0098664 a rdfs:Class ;
rdfs:label "G protein-coupled serotonin receptor signaling pathway" ;
rdfs:comment "The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands." ;
rdfs:subClassOf obo:GO_0007165 , obo:GO_0007186 .
obo:UBERON_0005408 a rdfs:Class ;
rdfs:label "circumventricular organ" ;
rdfs:comment "Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_1905458 a rdfs:Class ;
rdfs:label "positive regulation of lymphoid progenitor cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901534 , obo:GO_1905456 .
obo:PATO_0001046 a rdfs:Class ;
rdfs:label "resistance to" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's disposition to resist to a stimulus." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:GO_0055086 a rdfs:Class ;
rdfs:label "nucleobase-containing small molecule metabolic process" ;
rdfs:comment "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." ;
rdfs:subClassOf obo:GO_0006139 , obo:GO_0044281 .
obo:GO_0021732 a rdfs:Class ;
rdfs:label "midbrain-hindbrain boundary maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:UBERON_0001558 a rdfs:Class ;
rdfs:label "lower respiratory tract" ;
rdfs:comment "The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified]." ;
rdfs:subClassOf obo:UBERON_0000072 .
obo:GO_0008366 a rdfs:Class ;
rdfs:label "axon ensheathment" ;
rdfs:comment "Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal." ;
rdfs:subClassOf obo:GO_0007272 .
obo:GO_0048539 a rdfs:Class ;
rdfs:label "bone marrow development" ;
rdfs:comment "The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0009888 , obo:GO_0048534 , obo:GO_0048856 .
obo:GO_0010715 a rdfs:Class ;
rdfs:label "regulation of extracellular matrix disassembly" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903053 .
obo:PHIPO_0000205 a rdfs:Class ;
rdfs:label "decreased aerial height of filament"@en ;
rdfs:comment "An individual organism growth phenotype in which the aerial height of hyphae is decreased." ;
rdfs:subClassOf obo:PHIPO_0001212 .
obo:GO_0014028 a rdfs:Class ;
rdfs:label "notochord formation" ;
rdfs:comment "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PHIPO_0000030 a rdfs:Class ;
rdfs:label "pathogen penetration across the barrier absent" ;
rdfs:comment "A single species pathogen penetration phenotype in which pathogen penetration of a given experimental substance/membrane is absent." ;
rdfs:subClassOf obo:PHIPO_0000160 .
obo:CHEBI_28240 a rdfs:Class ;
rdfs:label "dichloroacetate" ;
rdfs:comment "A monocarboxylic acid anion that is the conjugate base of dichloroacetic acid." ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:CHEBI_26244 a rdfs:Class ;
rdfs:label "prenols" ;
rdfs:comment "Any alcohol possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of one or more isoprene units (biogenetic precursors of the isoprenoids)." ;
rdfs:subClassOf obo:CHEBI_24913 , obo:CHEBI_30879 .
obo:GO_0140112 a rdfs:Class ;
rdfs:label "extracellular vesicle biogenesis" ;
rdfs:comment "The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content." ;
rdfs:subClassOf obo:GO_0044085 .
obo:UBERON_0035809 a rdfs:Class ;
rdfs:label "serous cavity" ;
rdfs:subClassOf obo:UBERON_0002553 .
obo:UBERON_0002112 a rdfs:Class ;
rdfs:label "smooth muscle of esophagus" ;
rdfs:comment "A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 .
obo:GO_1905606 a rdfs:Class ;
rdfs:label "regulation of presynapse assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of presynapse assembly." ;
rdfs:subClassOf obo:GO_0051963 , obo:GO_0065007 , obo:GO_0099174 .
obo:PHIPO_0000710 a rdfs:Class ;
rdfs:label "resistance to dicloxacillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to dicloxacillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:PHIPO_0000242 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction protein complex localization" ;
rdfs:comment "A pathogen host interaction phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal." .
obo:GO_0007272 a rdfs:Class ;
rdfs:label "ensheathment of neurons" ;
rdfs:comment "The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment." ;
rdfs:subClassOf obo:GO_0009987 .
obo:CHEBI_140921 a rdfs:Class ;
rdfs:label "Hedgehog signaling pathway inhibitor" ;
rdfs:comment "Any pathway inhibitor that inhibits the Hedgehog signalling pathway." ;
rdfs:subClassOf obo:CHEBI_76932 .
obo:UBERON_0000992 a rdfs:Class ;
rdfs:label "ovary" ;
rdfs:comment "The gonad of a female organism which contains germ cells." ;
rdfs:subClassOf obo:UBERON_0000991 , obo:UBERON_0003134 .
obo:GO_0060341 a rdfs:Class ;
rdfs:label "regulation of cellular localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." ;
rdfs:subClassOf obo:GO_0032879 , obo:GO_0050794 , obo:GO_0065007 .
obo:UBERON_0001884 a rdfs:Class ;
rdfs:label "phrenic nerve" ;
rdfs:comment "A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium." ;
rdfs:subClassOf obo:UBERON_0001021 , obo:UBERON_0003443 .
obo:GO_1905039 a rdfs:Class ;
rdfs:label "carboxylic acid transmembrane transport" ;
rdfs:comment "The process in which carboxylic acid is transported across a membrane." ;
rdfs:subClassOf obo:GO_0046942 , obo:GO_0055085 .
obo:UBERON_0000201 a rdfs:Class ;
rdfs:label "endothelial blood brain barrier" ;
rdfs:comment "A blood brain barrier that is composed of endothelial cells." ;
rdfs:subClassOf obo:UBERON_0000120 .
obo:UBERON_0009614 a rdfs:Class ;
rdfs:label "hindbrain neural plate" ;
rdfs:comment "A neural plate that develops_from a presumptive hindbrain." ;
rdfs:subClassOf obo:UBERON_0003075 .
obo:CHEBI_22478 a rdfs:Class ;
rdfs:label "amino alcohol" ;
rdfs:comment "An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group." ;
rdfs:subClassOf obo:CHEBI_30879 , obo:CHEBI_50047 .
obo:GO_0021905 a rdfs:Class ;
rdfs:label "forebrain-midbrain boundary formation" ;
rdfs:comment "The process whose specific outcome is the creation of the forebrain-midbrain boundary." ;
rdfs:subClassOf obo:GO_0048646 , obo:GO_0048856 , obo:GO_0048859 .
obo:GO_0015804 a rdfs:Class ;
rdfs:label "neutral amino acid transport" ;
rdfs:comment "The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006865 .
obo:GO_0061854 a rdfs:Class ;
rdfs:label "positive regulation of neuroblast migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuroblast migration." ;
rdfs:subClassOf obo:GO_0030335 , obo:GO_0061853 , obo:GO_0065007 .
obo:GO_0032418 a rdfs:Class ;
rdfs:label "lysosome localization" ;
rdfs:comment "Any process in which a lysosome is transported to, and/or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_1990849 .
obo:UBERON_0004770 a rdfs:Class ;
rdfs:label "articular system" ;
rdfs:comment "Anatomical system that consists of all the joints of the body." ;
rdfs:subClassOf obo:UBERON_0034925 .
obo:PHIPO_0000706 a rdfs:Class ;
rdfs:label "resistance to tiamulin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tiamulin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0003367 a rdfs:Class ;
rdfs:label "cell-cell adhesion involved in ameboidal cell migration" ;
rdfs:comment "The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells." ;
rdfs:subClassOf obo:GO_0098609 .
obo:GO_0043292 a rdfs:Class ;
rdfs:label "contractile muscle fiber" ;
rdfs:comment "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." ;
rdfs:subClassOf obo:GO_0043232 , obo:GO_0099512 .
obo:PR_000001937 a rdfs:Class ;
rdfs:label "tartrate-resistant acid phosphatase type 5" ;
rdfs:comment "A protein that is a translation product of the human ACP5 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0045647 a rdfs:Class ;
rdfs:label "negative regulation of erythrocyte differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045638 , obo:GO_0045646 , obo:GO_0065007 .
obo:UBERON_0003854 a rdfs:Class ;
rdfs:label "spinal cord neural plate" ;
rdfs:comment "A neural plate that develops_from a future spinal cord." ;
rdfs:subClassOf obo:UBERON_0003075 .
obo:UBERON_0003571 a rdfs:Class ;
rdfs:label "trachea connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a trachea." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003580 .
obo:GO_0098794 a rdfs:Class ;
rdfs:label "postsynapse" ;
rdfs:comment "The part of a synapse that is part of the post-synaptic cell." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_46942 a rdfs:Class ;
rdfs:label "oxanes" ;
rdfs:comment "Any organic heteromonocyclic compoundthat is oxane or its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 .
obo:PHIPO_0000275 a rdfs:Class ;
rdfs:label "abnormal tissue phenotype"@en ;
rdfs:comment "A phenotype that shows detectable differences from normal at the level of a tissue (eg leaf, inflorescence, ear or kidney)." ;
rdfs:subClassOf obo:PHIPO_0000003 .
obo:PHIPO_0000611 a rdfs:Class ;
rdfs:label "resistance to fusidic acid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fusidic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_0012000 a rdfs:Class ;
rdfs:label "astrocyte of the forebrain" ;
rdfs:comment "An astrocyte of the forebrain." ;
rdfs:subClassOf obo:CL_0000127 , obo:CL_2000005 .
obo:UBERON_0002420 a rdfs:Class ;
rdfs:label "basal ganglion" ;
rdfs:comment "An individual member of a collection of basal ganglia. Basal ganglia are subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum[NIF,modified]." ;
rdfs:subClassOf obo:UBERON_0003528 , obo:UBERON_0007245 .
obo:GO_0010832 a rdfs:Class ;
rdfs:label "negative regulation of myotube differentiation" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ;
rdfs:subClassOf obo:GO_0010830 , obo:GO_0051154 , obo:GO_0065007 .
obo:UBERON_0003212 a rdfs:Class ;
rdfs:label "gustatory organ" ;
rdfs:comment "Any sense organ that functions in (some) detection of chemical stimulus involved in sensory perception of taste (GO:0050912)." ;
rdfs:subClassOf obo:UBERON_0000005 , obo:UBERON_0000062 .
obo:PHIPO_0000925 a rdfs:Class ;
rdfs:label "abnormal cell wall organization or biogenesis"@en ;
rdfs:comment "A cellular process phenotype in which the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000929 , obo:PHIPO_0000931 .
obo:CL_1000409 a rdfs:Class ;
rdfs:label "myocyte of sinoatrial node" ;
rdfs:comment "A muscle cell that is part of the sinoatrial node." ;
rdfs:subClassOf obo:CL_0000187 , obo:CL_0002072 , obo:CL_0008009 .
obo:UBERON_0001676 a rdfs:Class ;
rdfs:label "occipital bone" ;
rdfs:comment "The bone at the lower, posterior part of the skull." ;
rdfs:subClassOf obo:UBERON_0010428 , obo:UBERON_0011164 .
obo:UBERON_0001003 a rdfs:Class ;
rdfs:label "skin epidermis" ;
rdfs:comment "The outer epithelial layer of the skin that is superficial to the dermis." ;
rdfs:subClassOf obo:UBERON_0007376 , obo:UBERON_3000961 .
obo:UBERON_0002219 a rdfs:Class ;
rdfs:label "subfornical organ" ;
rdfs:comment "Group of neurons situated on the ventral surface of the fornix at the level of the foramen of Monro in the third ventricle (adapted from Wikipedia via NIF)." ;
rdfs:subClassOf obo:UBERON_0010135 .
obo:CL_0001065 a rdfs:Class ;
rdfs:label "innate lymphoid cell" ;
rdfs:comment "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses." ;
rdfs:subClassOf obo:CL_0000542 .
obo:PHIPO_0000156 a rdfs:Class ;
rdfs:label "increased RNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is increased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000152 .
obo:UBERON_0005400 a rdfs:Class ;
rdfs:label "telencephalon arachnoid mater" ;
rdfs:comment "An arachnoid mater that is part of a telencephalon." ;
rdfs:subClassOf obo:UBERON_0002362 , obo:UBERON_0003289 , obo:UBERON_0003556 .
obo:GO_0014904 a rdfs:Class ;
rdfs:label "myotube cell development" ;
rdfs:comment "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0055002 .
obo:GO_0051930 a rdfs:Class ;
rdfs:label "regulation of sensory perception of pain" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal." ;
rdfs:subClassOf obo:GO_0051931 , obo:GO_0065007 .
obo:GO_1903428 a rdfs:Class ;
rdfs:label "positive regulation of reactive oxygen species biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0065007 , obo:GO_1903426 , obo:GO_2000379 .
obo:CHEBI_27364 a rdfs:Class ;
rdfs:label "zinc molecular entity" ;
rdfs:subClassOf obo:CHEBI_33673 .
obo:CL_0002319 a rdfs:Class ;
rdfs:label "neural cell" ;
rdfs:comment "A cell that is part of the nervous system." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_0032271 a rdfs:Class ;
rdfs:label "regulation of protein polymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0065007 .
obo:GO_1902212 a rdfs:Class ;
rdfs:label "negative regulation of prolactin signaling pathway" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway." ;
rdfs:subClassOf obo:GO_0001960 , obo:GO_0065007 , obo:GO_1902211 .
obo:GO_0042177 a rdfs:Class ;
rdfs:label "negative regulation of protein catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0042176 , obo:GO_0051248 , obo:GO_0065007 .
obo:GO_0014043 a rdfs:Class ;
rdfs:label "negative regulation of neuron maturation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." ;
rdfs:subClassOf obo:GO_0014041 , obo:GO_0065007 , obo:GO_1903430 .
obo:UBERON_0004684 a rdfs:Class ;
rdfs:label "raphe nuclei" ;
rdfs:comment "The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_1904936 a rdfs:Class ;
rdfs:label "interneuron migration" ;
rdfs:comment "The orderly movement of an interneuron from one site to another." ;
rdfs:subClassOf obo:GO_0001764 , obo:GO_0016477 .
obo:PATO_0001402 a rdfs:Class ;
rdfs:label "multipotent" ;
rdfs:comment "A cellular potency that is the capacity to form multiple differentiated cell types." ;
rdfs:subClassOf obo:PATO_0001397 .
obo:GO_0002822 a rdfs:Class ;
rdfs:label "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." ;
rdfs:subClassOf obo:GO_0002819 , obo:GO_0065007 .
obo:GO_0036145 a rdfs:Class ;
rdfs:label "dendritic cell homeostasis" ;
rdfs:comment "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." ;
rdfs:subClassOf obo:GO_0001776 , obo:GO_0048872 .
obo:CL_0008034 a rdfs:Class ;
rdfs:label "mural cell"@en ;
rdfs:comment "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." ;
rdfs:subClassOf obo:CL_4033054 .
obo:GO_1904943 a rdfs:Class ;
rdfs:label "negative regulation of cardiac ventricle formation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901211 , obo:GO_1904413 , obo:GO_1904942 .
obo:PHIPO_0001277 a rdfs:Class ;
rdfs:label "presence of pathogen induced host DNA synthesis"@en ;
rdfs:comment "A pathogen host interaction phenotype in which host DNA synthesis occurs during pathogen infection (GO:0090592 DNA synthesis involved in DNA replication)." ;
rdfs:subClassOf obo:PHIPO_0001247 .
obo:CL_0000037 a rdfs:Class ;
rdfs:label "hematopoietic stem cell" ;
rdfs:comment "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000723 , obo:CL_0000988 , obo:CL_0008001 , obo:CL_0011026 .
obo:CHEBI_33231 a rdfs:Class ;
rdfs:label "antitubercular agent" ;
rdfs:comment "A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis." ;
rdfs:subClassOf obo:CHEBI_64912 .
obo:GO_0048596 a rdfs:Class ;
rdfs:label "embryonic camera-type eye morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the eye are generated and organized during embryonic development." ;
rdfs:subClassOf obo:GO_0048048 .
obo:GO_0051059 a rdfs:Class ;
rdfs:label "NF-kappaB binding" ;
rdfs:comment "Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0061629 .
obo:PHIPO_0000153 a rdfs:Class ;
rdfs:label "normal RNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000142 .
obo:CHEBI_83955 a rdfs:Class ;
rdfs:label "2-saturated fatty acid anion" ;
rdfs:comment "A fatty acid anion obtained by deprotonation of the carboxy group of any 2-saturated fatty acid." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:UBERON_0000490 a rdfs:Class ;
rdfs:label "unilaminar epithelium" ;
rdfs:comment "Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0010558 a rdfs:Class ;
rdfs:label "negative regulation of macromolecule biosynthetic process" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0010556 , obo:GO_0010605 , obo:GO_0065007 .
obo:UBERON_0006264 a rdfs:Class ;
rdfs:label "mouth-foregut junction" ;
rdfs:comment "An anatomical junctions that overlaps the mouth and foregut." ;
rdfs:subClassOf obo:UBERON_0007651 .
obo:PATO_0002198 a rdfs:Class ;
rdfs:label "quality of a substance" ;
rdfs:comment "A quality inhering in a bearer by virtue of its constitution." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:PHIPO_0001349 a rdfs:Class ;
rdfs:label "sensitive to pyrifenox" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrifenox. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0007645 a rdfs:Class ;
rdfs:label "future meninx" ;
rdfs:comment "A developing mesenchymal capsule that covers the developing brain and spinal cord and is the precursor of the meningeal cluster. In mammals this gives rise to the arachnoid mater, pia mater and dura mater. In cyclostomes and fishes, the future meninx gives rise to a single meningeal layer, the primitive meninx." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_0032871 a rdfs:Class ;
rdfs:label "regulation of karyogamy" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903353 .
obo:CHEBI_231550 a rdfs:Class ;
rdfs:label "azithromycin(2+)" ;
rdfs:comment "A tertiary ammonium ion resulting from the protonation of the two amino groups of azithromycin; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_137982 .
obo:GO_0048856 a rdfs:Class ;
rdfs:label "anatomical structure development" ;
rdfs:comment "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ;
rdfs:subClassOf obo:GO_0032502 .
obo:GO_0045765 a rdfs:Class ;
rdfs:label "regulation of angiogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of angiogenesis." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0065007 , obo:GO_1901342 .
obo:GO_0030485 a rdfs:Class ;
rdfs:label "smooth muscle contractile fiber" ;
rdfs:comment "The contractile fiber of smooth muscle cells." ;
rdfs:subClassOf obo:GO_0043292 .
obo:GO_0021584 a rdfs:Class ;
rdfs:label "pons formation" ;
rdfs:comment "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." ;
rdfs:subClassOf obo:GO_0048646 .
obo:UBERON_0010134 a rdfs:Class ;
rdfs:label "secretory circumventricular organ" ;
rdfs:comment "A circumventricular organ that is capable of secreting substances into the cerebrospinal fluid." ;
rdfs:subClassOf obo:UBERON_0005408 , obo:UBERON_0010133 .
obo:CHEBI_35902 a rdfs:Class ;
rdfs:label "oxo monocarboxylic acid anion" ;
rdfs:subClassOf obo:CHEBI_35757 , obo:CHEBI_35903 .
obo:UBERON_0015228 a rdfs:Class ;
rdfs:label "circulatory organ" ;
rdfs:comment "A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile." ;
rdfs:subClassOf obo:UBERON_0003103 .
obo:CHEBI_33267 a rdfs:Class ;
rdfs:label "elemental nitrogen" ;
rdfs:subClassOf obo:CHEBI_33465 , obo:CHEBI_51143 .
a rdfs:Class ;
rdfs:label "Caudoputamen" ;
rdfs:subClassOf , obo:UBERON_0005383 .
obo:GO_1900449 a rdfs:Class ;
rdfs:label "regulation of glutamate receptor signaling pathway" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0065007 .
obo:BFO_0000023 a rdfs:Class ;
rdfs:label "role"@en ;
rdfs:comment "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts."@en ;
rdfs:subClassOf obo:BFO_0000017 .
obo:GO_0014741 a rdfs:Class ;
rdfs:label "negative regulation of muscle hypertrophy" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy." ;
rdfs:subClassOf obo:GO_0014743 , obo:GO_0051241 , obo:GO_0065007 .
obo:PHIPO_0000468 a rdfs:Class ;
rdfs:label "absence of pathogen asexual spores within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host where the pathogen asexual spores are absent (FAO:0000023)." ;
rdfs:subClassOf obo:PHIPO_0000469 .
obo:GO_0071623 a rdfs:Class ;
rdfs:label "negative regulation of granulocyte chemotaxis" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0002689 , obo:GO_0065007 , obo:GO_0071622 .
obo:CL_4301583 a rdfs:Class ;
rdfs:label "CBX Purkinje Gaba_2 Purkinje cell (Mmus)" ;
rdfs:comment "A Purkinje cell of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1153 CBX Purkinje Gaba_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300353 .
obo:CHEBI_26739 a rdfs:Class ;
rdfs:label "sphingolipid" ;
rdfs:comment "Sphingolipids are a complex family of compounds that share a common structural feature, a sphingoid base backbone." ;
rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_35352 , obo:CHEBI_36963 .
obo:PHIPO_0001374 a rdfs:Class ;
rdfs:label "increased number of resting structures"@en ;
rdfs:comment "A single species phenotype where the frequency of occurrence of resting structures is increased." ;
rdfs:subClassOf obo:PHIPO_0001221 .
obo:CHEBI_49637 a rdfs:Class ;
rdfs:label "hydrogen atom" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_25585 , obo:CHEBI_33559 .
obo:CHEBI_35293 a rdfs:Class ;
rdfs:label "fused compound" ;
rdfs:comment "A polycyclic compound that contains more than one ring with at least two common atoms (also known as bridgehead carbons) that are adjacent to each other." ;
rdfs:subClassOf obo:CHEBI_33635 .
obo:GO_2001213 a rdfs:Class ;
rdfs:label "negative regulation of vasculogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0065007 , obo:GO_2001212 .
obo:CHEBI_39231 a rdfs:Class ;
rdfs:label "emamectin B1a" ;
rdfs:subClassOf obo:CHEBI_50346 .
obo:CHEBI_38808 a rdfs:Class ;
rdfs:label "calcium channel modulator" ;
rdfs:comment "A membrane transport modulator that is able to regulate intracellular calcium levels." ;
rdfs:subClassOf obo:CHEBI_38632 .
obo:PHIPO_0000253 a rdfs:Class ;
rdfs:label "normal RNA localization"@en ;
rdfs:comment "A single organism phenotype in which the localization of an RNA in a cell is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000249 .
obo:GO_0090171 a rdfs:Class ;
rdfs:label "chondrocyte morphogenesis" ;
rdfs:comment "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte." ;
rdfs:subClassOf obo:GO_0000902 , obo:GO_0009653 .
obo:UBERON_0001049 a rdfs:Class ;
rdfs:label "neural tube" ;
rdfs:comment "In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0003914 , obo:UBERON_0005291 , obo:UBERON_0010371 , obo:UBERON_0016879 .
obo:CHEBI_26401 a rdfs:Class ;
rdfs:label "purines" ;
rdfs:comment "A class of imidazopyrimidines that consists of purine and its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_35875 .
obo:GO_0017126 a rdfs:Class ;
rdfs:label "nucleologenesis" ;
rdfs:comment "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells." ;
rdfs:subClassOf obo:GO_0007000 , obo:GO_0044085 .
obo:PHIPO_0000216 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction disease symptom phenotype" .
obo:GO_1904026 a rdfs:Class ;
rdfs:label "regulation of collagen fibril organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of collagen fibril organization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903053 .
obo:GO_0046883 a rdfs:Class ;
rdfs:label "regulation of hormone secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0010817 , obo:GO_0023051 , obo:GO_0065007 , obo:GO_1903530 .
obo:CHEBI_59888 a rdfs:Class .
obo:UBERON_0004111 a rdfs:Class ;
rdfs:label "anatomical conduit" ;
rdfs:comment "Any tube, opening or passage that connects two distinct anatomical spaces." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:GO_0016477 a rdfs:Class ;
rdfs:label "cell migration" ;
rdfs:comment "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." ;
rdfs:subClassOf obo:GO_0048870 .
obo:GO_1903749 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to mitochondrion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to mitochondrion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903747 , obo:GO_1903829 .
obo:UBERON_0002105 a rdfs:Class ;
rdfs:label "vestibulo-auditory system" ;
rdfs:comment "Sensory system responsible for the perception of spatial orientation and auditory stimuli." ;
rdfs:subClassOf obo:UBERON_0001032 .
obo:GO_2000240 a rdfs:Class ;
rdfs:label "positive regulation of tRNA export from nucleus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus." ;
rdfs:subClassOf obo:GO_0046833 , obo:GO_0065007 , obo:GO_2000199 , obo:GO_2000238 .
obo:CL_0000499 a rdfs:Class ;
rdfs:label "stromal cell" ;
rdfs:comment "A connective tissue cell of an organ found in the loose connective tissue." ;
rdfs:subClassOf obo:CL_0002320 .
obo:GO_0006858 a rdfs:Class ;
rdfs:label "extracellular transport" ;
rdfs:comment "The transport of substances that occurs outside cells." ;
rdfs:subClassOf obo:GO_0006810 .
obo:GO_0051035 a rdfs:Class ;
rdfs:label "DNA transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 , obo:GO_0051032 .
obo:CHEBI_72579 a rdfs:Class ;
rdfs:label "tetrahydrochromenochromene" ;
rdfs:comment "Any chromenochromene resulting from the formal cis-fusion of two dihydro chromene rings, together with their substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_133135 .
obo:GO_0160043 a rdfs:Class ;
rdfs:label "catecholamine secretion, neurotransmission" ;
rdfs:comment "The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0007269 , obo:GO_0050432 .
obo:CHEBI_28201 a rdfs:Class ;
rdfs:label "rotenone" ;
rdfs:comment "A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy groups (the 2R,6aS,12aS-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of Derris elliptica)." ;
rdfs:subClassOf obo:CHEBI_38164 , obo:CHEBI_72581 .
obo:GO_0021848 a rdfs:Class ;
rdfs:label "neuroblast division in subpallium" ;
rdfs:comment "The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially." ;
rdfs:subClassOf obo:GO_0055057 .
obo:GO_0009306 a rdfs:Class ;
rdfs:label "protein secretion" ;
rdfs:comment "The controlled release of proteins from a cell." ;
rdfs:subClassOf obo:GO_0015031 , obo:GO_0032940 , obo:GO_0035592 , obo:GO_0046903 .
obo:CHEBI_25676 a rdfs:Class ;
rdfs:label "oligopeptide" ;
rdfs:comment "A peptide containing a relatively small number of amino acids." ;
rdfs:subClassOf obo:CHEBI_16670 .
obo:GO_0015630 a rdfs:Class ;
rdfs:label "microtubule cytoskeleton" ;
rdfs:comment "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." ;
rdfs:subClassOf obo:GO_0005856 .
obo:GO_0021688 a rdfs:Class ;
rdfs:label "cerebellar molecular layer formation" ;
rdfs:comment "The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0016236 a rdfs:Class ;
rdfs:label "macroautophagy" ;
rdfs:comment "The autophagic process that proceeds via the formation of an autophagosome." ;
rdfs:subClassOf obo:GO_0006914 .
obo:GO_0032387 a rdfs:Class ;
rdfs:label "negative regulation of intracellular transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0048523 , obo:GO_0051051 , obo:GO_0065007 .
obo:CHEBI_52214 a rdfs:Class ;
rdfs:label "ligand" ;
rdfs:comment "Any molecule or ion capable of binding to a central metal atom to form coordination complexes." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:PHIPO_0000835 a rdfs:Class ;
rdfs:label "sensitive to aureobasidin A"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to aureobasidin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_23114 a rdfs:Class ;
rdfs:label "chloride salt" ;
rdfs:subClassOf obo:CHEBI_23117 , obo:CHEBI_33958 .
obo:PHIPO_0000432 a rdfs:Class ;
rdfs:label "catalytic activity phenotype"@en ;
rdfs:comment "A single organism phenotype that affects a catalytic activity." ;
rdfs:subClassOf obo:PHIPO_0000411 .
obo:CHEBI_78840 a rdfs:Class ;
rdfs:label "olefinic compound" ;
rdfs:comment "Any organic molecular entity that contains at least one C=C bond." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:GO_0060842 a rdfs:Class ;
rdfs:label "arterial endothelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0060837 .
obo:CHEBI_26580 a rdfs:Class ;
rdfs:label "rifamycins" ;
rdfs:subClassOf obo:CHEBI_22565 , obo:CHEBI_39270 .
obo:UBERON_0015203 a rdfs:Class ;
rdfs:label "non-connected functional system" ;
rdfs:comment "An anatomical group whose component structures share a common function." ;
rdfs:subClassOf obo:UBERON_0034923 .
obo:UBERON_0005177 a rdfs:Class ;
rdfs:label "trunk region element" ;
rdfs:comment "An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:GO_0009085 a rdfs:Class ;
rdfs:label "L-lysine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of L-lysine, 2,6-diaminohexanoic acid." ;
rdfs:subClassOf obo:GO_0009067 .
obo:GO_0044001 a rdfs:Class ;
rdfs:label "migration in host" ;
rdfs:comment "The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0051701 .
obo:CL_0002589 a rdfs:Class ;
rdfs:label "smooth muscle cell of the brachiocephalic vasculature" ;
rdfs:comment "A smooth muscle cell of the bachiocephalic vasculature." ;
rdfs:subClassOf obo:CL_0000359 , obo:CL_0019018 .
obo:UBERON_0005856 a rdfs:Class ;
rdfs:label "developing mesenchymal condensation" ;
rdfs:comment "A delimited region of dense mesenchyme within looser mesenchyme." ;
rdfs:subClassOf obo:UBERON_0007524 , obo:UBERON_0011585 .
obo:CHEBI_39201 a rdfs:Class ;
rdfs:label "phenazines" ;
rdfs:comment "Any organonitrogen heterocyclic compound based on a phenazine skeleton and derivatives." ;
rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38101 .
obo:CL_4301602 a rdfs:Class ;
rdfs:label "Tanycyte NN_1 tanycyte (Mmus)" ;
rdfs:comment "A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cnmd (Mmus), Lpl (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1172 Tanycyte NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300362 .
obo:UBERON_0010741 a rdfs:Class ;
rdfs:label "bone of pectoral complex" ;
rdfs:comment "A bone that is part of a pectoral complex. Examples: scapula, manus phalanx, any carpal bone, any bone of the pectoral fin." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0010740 .
obo:GO_2000670 a rdfs:Class ;
rdfs:label "positive regulation of dendritic cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000108 , obo:GO_2000668 .
obo:CHEBI_45696 a rdfs:Class ;
rdfs:label "hydrogensulfate" ;
rdfs:subClassOf obo:CHEBI_33482 .
obo:PR_000001005 a rdfs:Class ;
rdfs:label "integrin alpha with A domain" ;
rdfs:comment "An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage." ;
rdfs:subClassOf obo:PR_000025796 .
obo:CHEBI_14321 a rdfs:Class .
obo:GO_0120035 a rdfs:Class ;
rdfs:label "regulation of plasma membrane bounded cell projection organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." ;
rdfs:subClassOf obo:GO_0031344 , obo:GO_0065007 .
obo:UBERON_0004731 a rdfs:Class ;
rdfs:label "neuromere" ;
rdfs:comment "A transverse unitary subdivision of the neural tube that shares a common dorsoventral structure (floor, basal, alar, and roof plates), but each having differential molecular identities and fates; they comprise the secondary prosencephalon, diencephalon (prosomeres), the midbrain (mesomeres), and the hindbrain (rhombomeres)." ;
rdfs:subClassOf obo:UBERON_0004732 .
obo:PHIPO_0000728 a rdfs:Class ;
rdfs:label "sensitive to emamectin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to emamectin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0015808 a rdfs:Class ;
rdfs:label "eye epithelium" ;
rdfs:comment "An epithelium that is part of a camera-type eye." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0019304 .
obo:GO_0051631 a rdfs:Class ;
rdfs:label "regulation of acetylcholine uptake" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell." ;
rdfs:subClassOf obo:GO_0051952 , obo:GO_0065007 .
obo:GO_0008150 a rdfs:Class ;
rdfs:label "biological_process" ;
rdfs:comment "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:GO_0009403 a rdfs:Class ;
rdfs:label "toxin biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." ;
rdfs:subClassOf obo:GO_0009404 , obo:GO_0044550 .
obo:PHIPO_0000504 a rdfs:Class ;
rdfs:label "obsolete deoxynivalenol present" ;
rdfs:comment "A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is normal (i.e. indistinguishable from wild type)." .
obo:CHEBI_38584 a rdfs:Class ;
rdfs:label "1,3-difluorobenzene" ;
rdfs:comment "A difluorobenzene carrying fluoro groups at positions 1 and 3." ;
rdfs:subClassOf obo:CHEBI_38582 .
obo:CHEBI_27561 a rdfs:Class ;
rdfs:label "oxirane" ;
rdfs:comment "A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom." ;
rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_36389 , obo:CHEBI_38104 .
obo:CHEBI_24951 a rdfs:Class ;
rdfs:label "kanamycins" ;
rdfs:subClassOf obo:CHEBI_22479 , obo:CHEBI_22507 .
obo:UBERON_0000389 a rdfs:Class ;
rdfs:label "lens cortex" ;
rdfs:comment "Tissue that surrounds the lens nucleus." ;
rdfs:subClassOf obo:UBERON_0000479 , obo:UBERON_0004121 .
obo:GO_0031175 a rdfs:Class ;
rdfs:label "neuron projection development" ;
rdfs:comment "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ;
rdfs:subClassOf obo:GO_0120036 .
obo:GO_0010570 a rdfs:Class ;
rdfs:label "regulation of filamentous growth" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape." ;
rdfs:subClassOf obo:GO_0040008 , obo:GO_0065007 .
obo:GO_0050865 a rdfs:Class ;
rdfs:label "regulation of cell activation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0051239 , obo:GO_0065007 .
obo:GO_0046673 a rdfs:Class ;
rdfs:label "negative regulation of compound eye retinal cell programmed cell death" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." ;
rdfs:subClassOf obo:GO_0046669 , obo:GO_0046671 , obo:GO_0065007 .
obo:CL_0000021 a rdfs:Class ;
rdfs:label "female germ cell" ;
rdfs:comment "Female germ cell is a germ cell that supports female gamete production." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000586 .
obo:CHEBI_28659 a rdfs:Class ;
rdfs:label "phosphorus atom" ;
rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33300 .
obo:CHEBI_64708 a rdfs:Class ;
rdfs:label "one-carbon compound" ;
rdfs:comment "An organic molecular entity containing a single carbon atom (C1)." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:GO_0048609 a rdfs:Class ;
rdfs:label "multicellular organismal reproductive process" ;
rdfs:comment "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." ;
rdfs:subClassOf obo:GO_0022414 .
obo:GO_0070382 a rdfs:Class ;
rdfs:label "exocytic vesicle" ;
rdfs:comment "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." ;
rdfs:subClassOf obo:GO_0030133 , obo:GO_0099503 .
obo:GO_0048823 a rdfs:Class ;
rdfs:label "nucleate erythrocyte development" ;
rdfs:comment "The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048821 .
obo:CHEBI_71989 a rdfs:Class ;
rdfs:label "ortho ester" ;
rdfs:comment "Any organooxygen compound that has the general formula RC(OR1)(OR2)(OR3), where R1, R2, R3 ≠ H." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:CHEBI_50996 a rdfs:Class ;
rdfs:label "tertiary amino compound" ;
rdfs:comment "A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:GO_0032226 a rdfs:Class ;
rdfs:label "positive regulation of synaptic transmission, dopaminergic" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." ;
rdfs:subClassOf obo:GO_0032225 , obo:GO_0050806 , obo:GO_0065007 .
obo:PHIPO_0001028 a rdfs:Class ;
rdfs:label "abolished protein localization to plasma membrane"@en ;
rdfs:comment "A single organism phenotype in which the localization of a protein to the plasma membrane is abolished (GO:0072659)." ;
rdfs:subClassOf obo:PHIPO_0000245 .
obo:CHEBI_46913 a rdfs:Class ;
rdfs:label "ornithinium(2+)" ;
rdfs:subClassOf obo:CHEBI_33719 .
obo:GO_1990542 a rdfs:Class ;
rdfs:label "mitochondrial transmembrane transport" ;
rdfs:comment "The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion." ;
rdfs:subClassOf obo:GO_0006839 , obo:GO_0046907 , obo:GO_0055085 .
obo:GO_0006836 a rdfs:Class ;
rdfs:label "neurotransmitter transport" ;
rdfs:comment "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." ;
rdfs:subClassOf obo:GO_0006810 .
obo:CL_0001054 a rdfs:Class ;
rdfs:label "CD14-positive monocyte" ;
rdfs:comment "A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20." ;
rdfs:subClassOf obo:CL_0000576 .
obo:CHEBI_60600 a rdfs:Class ;
rdfs:label "amide fungicide" ;
rdfs:comment "Compounds that contain an amide group as a key feature of their structure and which have been used as fungicides." ;
rdfs:subClassOf obo:CHEBI_87012 .
obo:GO_0032365 a rdfs:Class ;
rdfs:label "intracellular lipid transport" ;
rdfs:comment "The directed movement of lipids within cells." ;
rdfs:subClassOf obo:GO_0006869 , obo:GO_0046907 .
obo:PHIPO_0001202 a rdfs:Class ;
rdfs:label "obsolete loss of functional pathogen effector" ;
rdfs:comment "A phenotype where the ability of a pathogen effector to produce an infectious disease is abolished." .
obo:GO_0036477 a rdfs:Class ;
rdfs:label "somatodendritic compartment" ;
rdfs:comment "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_2001055 a rdfs:Class ;
rdfs:label "positive regulation of mesenchymal cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0065007 , obo:GO_2001053 .
obo:GO_0043022 a rdfs:Class ;
rdfs:label "ribosome binding" ;
rdfs:comment "Binding to a ribosome." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0043021 .
obo:UBERON_0006134 a rdfs:Class ;
rdfs:label "nerve fiber" ;
rdfs:comment "A threadlike extension of a nerve cell and consists of an axon and myelin sheath (if it is myelinated) in the nervous system. There are nerve fibers in the central nervous system and peripheral nervous system. A nerve fiber may be myelinated and/or unmyelinated. In the central nervous system (CNS), myelin by oligodendroglia cells is formed. Schwann cells form myelin in the peripheral nervous system (PNS). Schwann cells also make a thin covering in an axon without myelin (in the PNS). A peripheral nerve fiber contains an axon, myelin sheath, schwann cells and its endoneurium. There are no endoneurium and schwann cells in the central nervous system." ;
rdfs:subClassOf obo:UBERON_0005162 .
obo:GO_0098590 a rdfs:Class ;
rdfs:label "plasma membrane region" ;
rdfs:comment "A membrane that is a (regional) part of the plasma membrane." ;
rdfs:subClassOf obo:GO_0016020 .
obo:CL_4310056 a rdfs:Class ;
rdfs:label "SN PAX7 GABA GABAergic neuron (Primate)" ;
rdfs:comment "A GABAergic neuron of the Primates brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Subclass:SN PAX7 GABA." ;
rdfs:subClassOf obo:CL_0000617 .
obo:CHEBI_16240 a rdfs:Class ;
rdfs:label "hydrogen peroxide" ;
rdfs:comment "An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond." ;
rdfs:subClassOf obo:CHEBI_24837 , obo:CHEBI_26523 .
obo:UBERON_0010199 a rdfs:Class ;
rdfs:label "bona-fide anatomical boundary" ;
rdfs:comment "An anatomical boundary that corresponds to some physical discontinuity." ;
rdfs:subClassOf obo:UBERON_0000466 .
obo:GO_1904987 a rdfs:Class ;
rdfs:label "regulation of endothelial cell activation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endothelial cell activation." ;
rdfs:subClassOf obo:GO_0050865 , obo:GO_0065007 .
obo:UBERON_8450002 a rdfs:Class ;
rdfs:label "excretory system" ;
rdfs:comment "An anatomical system that eliminates waste products that arise as a result of metabolic activity." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:GO_0033242 a rdfs:Class ;
rdfs:label "negative regulation of amine catabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0033239 , obo:GO_0033241 , obo:GO_0065007 .
obo:UBERON_0006677 a rdfs:Class ;
rdfs:label "surface of epithelium" ;
rdfs:comment "An anatomical boundary that adjacent_to a epithelium." ;
rdfs:subClassOf obo:UBERON_0036215 .
obo:UBERON_0008339 a rdfs:Class ;
rdfs:label "microvascular endothelium" ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0004638 .
obo:GO_0048699 a rdfs:Class ;
rdfs:label "generation of neurons" ;
rdfs:comment "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." ;
rdfs:subClassOf obo:GO_0022008 .
obo:GO_0072656 a rdfs:Class ;
rdfs:label "maintenance of protein location in mitochondrion" ;
rdfs:comment "Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0072595 .
obo:CL_0000397 a rdfs:Class ;
rdfs:label "ganglion interneuron" ;
rdfs:comment "Any interneuron that has its soma located in some ganglion." ;
rdfs:subClassOf obo:CL_0000099 .
obo:CHEBI_30106 a rdfs:Class ;
rdfs:label "azo group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:PHIPO_0000355 a rdfs:Class ;
rdfs:label "pathogen penetration into host absent"@en ;
rdfs:comment "A pathogen entry into host phenotype in which pathogen penetration into the body, tissues, or cells of the host organism is absent." ;
rdfs:subClassOf obo:PHIPO_0000949 .
obo:UBERON_0000482 a rdfs:Class ;
rdfs:label "basal lamina of epithelium" ;
rdfs:comment "Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue." ;
rdfs:subClassOf obo:UBERON_0005764 .
obo:GO_0035701 a rdfs:Class ;
rdfs:label "hematopoietic stem cell migration" ;
rdfs:comment "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." ;
rdfs:subClassOf obo:GO_0016477 .
obo:PHIPO_0000005 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogenicity" ;
rdfs:comment "A phenotype where the pathogenicity is abnormal (i.e different than wild-type)" .
obo:GO_0014007 a rdfs:Class ;
rdfs:label "negative regulation of microglia differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell." ;
rdfs:subClassOf obo:GO_0014006 , obo:GO_0045650 , obo:GO_0045686 , obo:GO_0065007 .
obo:GO_0005884 a rdfs:Class ;
rdfs:label "actin filament" ;
rdfs:comment "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." ;
rdfs:subClassOf obo:GO_0099513 .
obo:UBERON_0000105 a rdfs:Class ;
rdfs:label "life cycle stage" ;
rdfs:comment "A spatiotemporal region encompassing some part of the life cycle of an organism." ;
rdfs:subClassOf obo:BFO_0000015 , obo:UBERON_0000000 .
obo:CHEBI_16150 a rdfs:Class ;
rdfs:label "benzoate" ;
rdfs:comment "The simplest member of the class of benzoates that is the conjugate base of benzoic acid, comprising a benzoic acid core with a proton missing to give a charge of -1." ;
rdfs:subClassOf obo:CHEBI_22718 .
obo:GO_0051960 a rdfs:Class ;
rdfs:label "regulation of nervous system development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000026 .
obo:CHEBI_48379 a rdfs:Class ;
rdfs:label "isourea" ;
rdfs:comment "A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives." ;
rdfs:subClassOf obo:CHEBI_48378 .
obo:GO_1905521 a rdfs:Class ;
rdfs:label "regulation of macrophage migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of macrophage migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0071675 .
obo:PHIPO_0000257 a rdfs:Class ;
rdfs:label "abnormal transport"@en ;
rdfs:comment "A single organism phenotype in which a specific transport process is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000256 , obo:PHIPO_0001094 .
obo:CL_0000348 a rdfs:Class ;
rdfs:label "choroidal cell of the eye" ;
rdfs:comment "A cell that is part of optic choroid." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_1902868 a rdfs:Class ;
rdfs:label "positive regulation of retina development in camera-type eye" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1902866 .
obo:CHEBI_59869 a rdfs:Class ;
rdfs:label "L-alpha-amino acid zwitterion" ;
rdfs:comment "Zwitterionic form of an L-α-amino acid having an anionic carboxy group and a protonated amino group." ;
rdfs:subClassOf obo:CHEBI_78608 .
obo:UBERON_0003474 a rdfs:Class ;
rdfs:label "meningeal artery" ;
rdfs:comment "One of the arteries supplying a meninix[Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:GO_0043233 a rdfs:Class ;
rdfs:label "organelle lumen" ;
rdfs:comment "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." ;
rdfs:subClassOf obo:GO_0031974 .
obo:GO_1990234 a rdfs:Class ;
rdfs:label "transferase complex" ;
rdfs:comment "A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)." ;
rdfs:subClassOf obo:GO_1902494 .
obo:PHIPO_0000496 a rdfs:Class ;
rdfs:label "toxin biosynthetic process phenotype"@en ;
rdfs:comment "A single organism phenotype that affects the chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." ;
rdfs:subClassOf obo:PHIPO_0000495 .
obo:UBERON_0003082 a rdfs:Class ;
rdfs:label "myotome" ;
rdfs:comment "A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells." ;
rdfs:subClassOf obo:UBERON_0017650 .
obo:UBERON_0001772 a rdfs:Class ;
rdfs:label "corneal epithelium" ;
rdfs:comment "The smooth stratified squamous epithelium that covers the outer surface of the cornea." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0015808 .
obo:PHIPO_0001067 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction organism level phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that is observed at the level of an individual organism (eg a worm host)." .
obo:UBERON_0006238 a rdfs:Class ;
rdfs:label "future brain" ;
rdfs:comment "The embryonic precursor of the brain." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:UBERON_0006904 a rdfs:Class ;
rdfs:label "head mesenchyme from mesoderm" ;
rdfs:comment "A head mesenchyme that develops_from a mesoderm." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0005253 .
obo:UBERON_0009891 a rdfs:Class ;
rdfs:label "facial mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a developing face." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005253 .
obo:GO_0044281 a rdfs:Class ;
rdfs:label "small molecule metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." ;
rdfs:subClassOf obo:GO_0008152 .
obo:PHIPO_0000667 a rdfs:Class ;
rdfs:label "resistance to cefotaxime"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cefotaxime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_2000374 a rdfs:Class ;
rdfs:label "regulation of oxygen metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of oxygen metabolic process." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:UBERON_0004909 a rdfs:Class ;
rdfs:label "epithelium of gonad" ;
rdfs:comment "An epithelium surrounding a gonad." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0005156 .
obo:GO_0051640 a rdfs:Class ;
rdfs:label "organelle localization" ;
rdfs:comment "Any process in which an organelle is transported to, and/or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051179 .
obo:GO_0032292 a rdfs:Class ;
rdfs:label "peripheral nervous system axon ensheathment" ;
rdfs:comment "The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." ;
rdfs:subClassOf obo:GO_0008366 .
obo:PHIPO_0000048 a rdfs:Class ;
rdfs:label "abnormal sexual reproduction"@en ;
rdfs:comment "A single species phenotype where the sexual reproduction process in which new individuals are produced by combining the genetic material of two gametes, which may come from two organisms or from a single organism is abnormal (GO:0019953)." ;
rdfs:subClassOf obo:PHIPO_0000043 .
obo:PHIPO_0001255 a rdfs:Class ;
rdfs:label "increased host immune inflammatory response with pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection occurs to a greater extent than normal. (GO:0006954 inflammatory response)." ;
rdfs:subClassOf obo:PHIPO_0001253 .
obo:GO_1903047 a rdfs:Class ;
rdfs:label "mitotic cell cycle process" ;
rdfs:comment "A process that is part of the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0022402 .
obo:CHEBI_145556 a rdfs:Class ;
rdfs:label "macrodiolide" ;
rdfs:comment "A macropolylide which contains two ester linkages in one macrocyclic ring." ;
rdfs:subClassOf obo:CHEBI_145555 .
obo:CL_4030029 a rdfs:Class ;
rdfs:label "blood lymphocyte" ;
rdfs:comment "A lymphocyte located in blood." ;
rdfs:subClassOf obo:CL_0000542 , obo:CL_2000001 .
obo:GO_2000385 a rdfs:Class ;
rdfs:label "positive regulation of ectoderm development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of ectoderm development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_2000383 .
obo:GO_0051327 a rdfs:Class ;
rdfs:label "meiotic M phase" ;
rdfs:comment "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0000279 , obo:GO_0098762 .
obo:CHEBI_77308 a rdfs:Class ;
rdfs:label "ethylenebis(dithiocarbamate)" ;
rdfs:comment "A member of the class of dithiocarbamate anions resulting from the deprotonation of both of the dithiocarbamic acid moieties of ethylenebis(dithiocarbamic acid). The major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_84292 .
obo:GO_2000543 a rdfs:Class ;
rdfs:label "positive regulation of gastrulation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of gastrulation." ;
rdfs:subClassOf obo:GO_0010470 , obo:GO_0040019 , obo:GO_0065007 .
obo:GO_0048369 a rdfs:Class ;
rdfs:label "lateral mesoderm morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the lateral mesoderm are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048332 , obo:GO_0072132 .
obo:CL_0000300 a rdfs:Class ;
rdfs:label "gamete" ;
rdfs:comment "A mature sexual reproductive cell having a single set of unpaired chromosomes." ;
rdfs:subClassOf obo:CL_0000413 , obo:CL_0000586 .
obo:CHEBI_60258 a rdfs:Class ;
rdfs:label "EC 3.4.* (hydrolases acting on peptide bond) inhibitor" ;
rdfs:comment "A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*)." ;
rdfs:subClassOf obo:CHEBI_76759 .
obo:GO_0140899 a rdfs:Class ;
rdfs:label "plastid gene expression" ;
rdfs:comment "The process in which a plastid gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." ;
rdfs:subClassOf obo:GO_0010467 .
obo:CHEBI_4194 a rdfs:Class ;
rdfs:label "D-hexose" ;
rdfs:comment "A hexose that has D-configuration at position 5." ;
rdfs:subClassOf obo:CHEBI_18133 .
obo:CHEBI_27171 a rdfs:Class ;
rdfs:label "organic heterobicyclic compound" ;
rdfs:subClassOf obo:CHEBI_33672 , obo:CHEBI_38166 .
obo:GO_0034220 a rdfs:Class ;
rdfs:label "monoatomic ion transmembrane transport" ;
rdfs:comment "A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ;
rdfs:subClassOf obo:GO_0006811 , obo:GO_0055085 .
obo:UBERON_0000454 a rdfs:Class ;
rdfs:label "cerebral subcortex" ;
rdfs:comment "The layer located below the cerebral cortex that includes the forebrain, midbrain and hindbrain." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:UBERON_0006596 a rdfs:Class ;
rdfs:label "presumptive blood" ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:PHIPO_0000985 a rdfs:Class ;
rdfs:label "decreased extent of pathogen-associated host lesions"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion occurs to a lesser extent than normal." ;
rdfs:subClassOf obo:PHIPO_0000480 .
obo:GO_1904172 a rdfs:Class ;
rdfs:label "positive regulation of bleb assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of bleb assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120034 , obo:GO_1904170 .
obo:PHIPO_0001161 a rdfs:Class ;
rdfs:label "host defense-induced phenolic compound absent"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the host phenolic compounds usually present during infection are absent or at a level too low to detect." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:GO_1902876 a rdfs:Class ;
rdfs:label "negative regulation of embryonic pattern specification" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification." ;
rdfs:subClassOf obo:GO_0051241 , obo:GO_0065007 , obo:GO_1902875 .
obo:GO_0032353 a rdfs:Class ;
rdfs:label "negative regulation of hormone biosynthetic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0032351 , obo:GO_0046885 , obo:GO_0065007 .
obo:CHEBI_48960 a rdfs:Class ;
rdfs:label "bis(azo) compound" ;
rdfs:comment "Any azo compound containing two ‒N=N‒ groups." ;
rdfs:subClassOf obo:CHEBI_37533 .
obo:GO_0048715 a rdfs:Class ;
rdfs:label "negative regulation of oligodendrocyte differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045686 , obo:GO_0048713 , obo:GO_0065007 .
obo:CHEBI_60643 a rdfs:Class ;
rdfs:label "NMDA receptor antagonist" ;
rdfs:comment "Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs." ;
rdfs:subClassOf obo:CHEBI_60798 .
obo:UBERON_0005800 a rdfs:Class ;
rdfs:label "section of aorta" ;
rdfs:comment "Any portion of the aorta including the ascending and descending aorta, and aortic arch or a portion of the aortic orifice of the left ventricle." ;
rdfs:subClassOf obo:UBERON_0013522 .
obo:GO_0090140 a rdfs:Class ;
rdfs:label "regulation of mitochondrial fission" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments." ;
rdfs:subClassOf obo:GO_0010821 , obo:GO_0022603 , obo:GO_0065007 .
obo:CHEBI_23232 a rdfs:Class ;
rdfs:label "chromenes" ;
rdfs:subClassOf obo:CHEBI_38443 .
obo:CHEBI_48339 a rdfs:Class ;
rdfs:label "1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine" ;
rdfs:comment "A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively." ;
rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_24780 , obo:CHEBI_25698 , obo:CHEBI_39430 , obo:CHEBI_46844 , obo:CHEBI_46848 .
obo:CHEBI_28909 a rdfs:Class ;
rdfs:label "iprodione" ;
rdfs:comment "An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide." ;
rdfs:subClassOf obo:CHEBI_24628 , obo:CHEBI_47857 , obo:CHEBI_87068 , obo:CHEBI_87197 .
obo:CHEBI_74159 a rdfs:Class ;
rdfs:label "D-cycloserine zwitterion" ;
rdfs:comment "A zwitterion resulting from the transfer of a proton from the ring nitrogen to the primary amino group of D-cycloserine. The major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:CHEBI_132142 a rdfs:Class ;
rdfs:label "1,4-naphthoquinones" ;
rdfs:comment "A naphthoquinone in which the oxo groups of the quinone moiety are at positions 1 and 4 of the parent naphthalene ring." ;
rdfs:subClassOf obo:CHEBI_25481 , obo:CHEBI_25830 .
obo:UBERON_0012321 a rdfs:Class ;
rdfs:label "deep cervical artery" ;
rdfs:comment "The deep cervical artery (Profunda cervicalis) is an artery of the neck." ;
rdfs:subClassOf obo:UBERON_0012320 .
obo:GO_2000548 a rdfs:Class ;
rdfs:label "negative regulation of dendritic cell dendrite assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120033 , obo:GO_2000547 .
obo:CHEBI_36141 a rdfs:Class ;
rdfs:label "quinone" ;
rdfs:comment "Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of ‒CH= groups into ‒C(=O)‒ groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included)." ;
rdfs:subClassOf obo:CHEBI_3992 .
obo:GO_0042422 a rdfs:Class ;
rdfs:label "norepinephrine catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0042415 , obo:GO_0042424 .
obo:PHIPO_0001416 a rdfs:Class ;
rdfs:label "normal growth on thifluzamide" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to thifluzamide (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CL_0002073 a rdfs:Class ;
rdfs:label "transitional myocyte" ;
rdfs:comment "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes." ;
rdfs:subClassOf obo:CL_0002086 .
obo:GO_0045770 a rdfs:Class ;
rdfs:label "positive regulation of asymmetric cell division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." ;
rdfs:subClassOf obo:GO_0009786 , obo:GO_0051781 , obo:GO_0065007 .
obo:GO_1903294 a rdfs:Class ;
rdfs:label "regulation of glutamate secretion, neurotransmission" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission." ;
rdfs:subClassOf obo:GO_0014048 , obo:GO_0046928 , obo:GO_0051966 , obo:GO_0065007 .
obo:GO_0120039 a rdfs:Class ;
rdfs:label "plasma membrane bounded cell projection morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048858 .
obo:GO_1901605 a rdfs:Class ;
rdfs:label "alpha-amino acid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving an alpha-amino acid." ;
rdfs:subClassOf obo:GO_0006520 , obo:GO_0008152 , obo:GO_0019752 .
obo:GO_0003674 a rdfs:Class ;
rdfs:label "molecular_function" ;
rdfs:comment "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:UBERON_0014455 a rdfs:Class ;
rdfs:label "subcutaneous abdominal adipose tissue" ;
rdfs:comment "Subcutaneous adipose tissue that is located in the abdominal region." ;
rdfs:subClassOf obo:UBERON_0001013 , obo:UBERON_0002190 , obo:UBERON_0007808 .
obo:PHIPO_0000369 a rdfs:Class ;
rdfs:label "abnormal formation of pathogen penetration structure when near host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the formation of the pathogen penetration structure is abnormal (i.e different than wild-type)." ;
rdfs:subClassOf obo:PHIPO_0000949 .
obo:GO_0002460 a rdfs:Class ;
rdfs:label "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" ;
rdfs:comment "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." ;
rdfs:subClassOf obo:GO_0002250 .
obo:GO_0014039 a rdfs:Class ;
rdfs:label "negative regulation of Schwann cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation." ;
rdfs:subClassOf obo:GO_0014038 , obo:GO_0045686 , obo:GO_0065007 .
obo:PHIPO_0000139 a rdfs:Class ;
rdfs:label "abnormal protein complex binding"@en ;
rdfs:comment "A single species molecular function phenotype in which the binding of one protein to a protein complex is abnormal. The protein whose binding to the protein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000133 .
obo:GO_0030100 a rdfs:Class ;
rdfs:label "regulation of endocytosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endocytosis." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0060627 , obo:GO_0065007 .
obo:UBERON_0008884 a rdfs:Class ;
rdfs:label "left putamen" ;
rdfs:comment "A putamen that is part of a left cerebral hemisphere." ;
rdfs:subClassOf obo:UBERON_0001874 .
obo:GO_0051651 a rdfs:Class ;
rdfs:label "maintenance of location in cell" ;
rdfs:comment "Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0051235 .
obo:PHIPO_0000990 a rdfs:Class ;
rdfs:label "obsolete absence of pathogen protein with host" ;
rdfs:comment "A pathogen host interaction phenotype, in which the pathogen produced protein usually present during infection is absent." .
obo:CHEBI_35550 a rdfs:Class ;
rdfs:label "1H-1,2,4-triazole" ;
rdfs:subClassOf obo:CHEBI_35560 .
obo:PATO_0001581 a rdfs:Class ;
rdfs:label "decreased contractility" ;
rdfs:comment "A contractility which is relatively low." ;
rdfs:subClassOf obo:PATO_0001690 , obo:PATO_0002303 .
obo:UBERON_0004370 a rdfs:Class ;
rdfs:label "anterior limiting lamina of cornea" ;
rdfs:comment "A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane." ;
rdfs:subClassOf obo:UBERON_0000061 , obo:UBERON_0005769 .
obo:UBERON_3000961 a rdfs:Class ;
rdfs:label "external integument structure" ;
rdfs:comment "Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument." ;
rdfs:subClassOf obo:UBERON_0003102 .
obo:GO_0007507 a rdfs:Class ;
rdfs:label "heart development" ;
rdfs:comment "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:PHIPO_0000307 a rdfs:Class ;
rdfs:label "obsolete normal effector of pathogenicity" ;
rdfs:comment "The ability to cause disease by activating or suppressing host defenses is unaltered compared to the wildtype interaction. This may result in the outcome of being pathogenic or not-pathogenic." .
obo:CL_0002463 a rdfs:Class ;
rdfs:label "SIRPa-positive adipose dendritic cell" ;
rdfs:comment "An adipose dendritic cell that is SIRPa-positive." ;
rdfs:subClassOf obo:CL_0000990 , obo:CL_0002462 .
obo:UBERON_0000304 a rdfs:Class ;
rdfs:label "tendon sheath" ;
rdfs:comment "A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:CHEBI_22221 a rdfs:Class ;
rdfs:label "acyl group" ;
rdfs:comment "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:GO_0015837 a rdfs:Class ;
rdfs:label "amine transport" ;
rdfs:comment "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0071705 .
obo:GO_1902262 a rdfs:Class ;
rdfs:label "apoptotic process involved in blood vessel morphogenesis" ;
rdfs:comment "Any apoptotic process that is involved in blood vessel morphogenesis." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0060561 .
a rdfs:Class ;
rdfs:label "Hypothalamus" ;
rdfs:subClassOf , obo:UBERON_0001898 .
obo:GO_2000508 a rdfs:Class ;
rdfs:label "regulation of dendritic cell chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis." ;
rdfs:subClassOf obo:GO_0002688 , obo:GO_0065007 , obo:GO_0071675 .
obo:PR_P22858 a rdfs:Class ;
rdfs:label "parathyroid hormone-related protein (mouse)" ;
rdfs:comment "A parathyroid hormone-related protein that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000013433 , obo:PR_000029032 .
obo:GO_0002269 a rdfs:Class ;
rdfs:label "leukocyte activation involved in inflammatory response" ;
rdfs:comment "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response." ;
rdfs:subClassOf obo:GO_0045321 .
obo:GO_0045453 a rdfs:Class ;
rdfs:label "bone resorption" ;
rdfs:comment "The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products." ;
rdfs:subClassOf obo:GO_0001894 .
obo:CHEBI_33249 a rdfs:Class ;
rdfs:label "organyl group" ;
rdfs:comment "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." ;
rdfs:subClassOf obo:CHEBI_51447 .
obo:PHIPO_0000320 a rdfs:Class ;
rdfs:label "obsolete increased effector of virulence suppression of host defense" ;
rdfs:comment "The pathogen effector entity has an increased ability to suppress host defense." .
obo:GO_0034599 a rdfs:Class ;
rdfs:label "cellular response to oxidative stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0006979 , obo:GO_0062197 .
obo:GO_2000194 a rdfs:Class ;
rdfs:label "regulation of female gonad development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of female gonad development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905939 , obo:GO_2000026 .
obo:UBERON_0001536 a rdfs:Class ;
rdfs:label "left common carotid artery plus branches" ;
rdfs:comment "The leftmost of the two common carotid arteries, originating from the aortic arch in the thorax." ;
rdfs:subClassOf obo:UBERON_0001530 .
obo:UBERON_0004642 a rdfs:Class ;
rdfs:label "third ventricle ependyma" ;
rdfs:comment "An ependyma that is part of a third ventricle [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0004670 , obo:UBERON_0005357 .
obo:UBERON_0002271 a rdfs:Class ;
rdfs:label "periventricular zone of hypothalamus" ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:GO_0051169 a rdfs:Class ;
rdfs:label "nuclear transport" ;
rdfs:comment "The directed movement of substances into, out of, or within the nucleus." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0046907 .
obo:UBERON_0003827 a rdfs:Class ;
rdfs:label "thoracic segment bone" ;
rdfs:comment "A bone that is part of a thorax [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0003463 , obo:UBERON_0005181 .
obo:GO_0061523 a rdfs:Class ;
rdfs:label "cilium disassembly" ;
rdfs:comment "A cellular process that results in the breakdown of a cilium." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0044782 , obo:GO_1903008 .
obo:PATO_0000574 a rdfs:Class ;
rdfs:label "decreased length" ;
rdfs:comment "A length quality which is relatively small." ;
rdfs:subClassOf obo:PATO_0000122 , obo:PATO_0000587 .
obo:PHIPO_0001422 a rdfs:Class ;
rdfs:label "normal growth on flutolanil" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to flutolanil (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0016050 a rdfs:Class ;
rdfs:label "vesicle organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0016043 .
obo:GO_0036160 a rdfs:Class ;
rdfs:label "melanocyte-stimulating hormone secretion" ;
rdfs:comment "The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation." ;
rdfs:subClassOf obo:GO_0030072 .
obo:GO_0042480 a rdfs:Class ;
rdfs:label "negative regulation of eye photoreceptor cell development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0042478 , obo:GO_0065007 .
obo:GO_0045088 a rdfs:Class ;
rdfs:label "regulation of innate immune response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." ;
rdfs:subClassOf obo:GO_0002831 , obo:GO_0031347 , obo:GO_0032101 , obo:GO_0050776 , obo:GO_0065007 .
obo:GO_0060950 a rdfs:Class ;
rdfs:label "cardiac glial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart." ;
rdfs:subClassOf obo:GO_0010001 , obo:GO_0030154 , obo:GO_0035051 .
obo:GO_0030150 a rdfs:Class ;
rdfs:label "protein import into mitochondrial matrix" ;
rdfs:comment "The import of proteins with mitochondrial targeting sequence from the cytosol across the mitochondrial outer and inner membranes into the matrix via TOM-TIM23-PAM." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0044743 , obo:GO_0070585 , obo:GO_0170036 , obo:GO_7770058 .
obo:GO_0050769 a rdfs:Class ;
rdfs:label "positive regulation of neurogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0050767 , obo:GO_0051962 , obo:GO_0065007 .
obo:CHEBI_84004 a rdfs:Class ;
rdfs:label "(S)-triadimefon" ;
rdfs:comment "A 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one that is the (S)-enantiomer of triadimefon." ;
rdfs:subClassOf obo:CHEBI_84002 .
obo:CL_0000557 a rdfs:Class ;
rdfs:label "granulocyte monocyte progenitor cell" ;
rdfs:comment "A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1." ;
rdfs:subClassOf obo:CL_0000763 , obo:CL_0001012 , obo:CL_0002032 , obo:CL_1001610 .
obo:CL_4030045 a rdf:Property ;
rdfs:label "lacks_part" ;
rdfs:range .
obo:GO_0032890 a rdfs:Class ;
rdfs:label "regulation of organic acid transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:CHEBI_42266 a rdfs:Class ;
rdfs:label "ethane" ;
rdfs:comment "An alkane comprising of two carbon atoms." ;
rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18310 .
obo:PHIPO_0001215 a rdfs:Class ;
rdfs:label "abnormal hyphal growth"@en ;
rdfs:comment "An individual organism growth phenotype in which the size or extent of directional growth of hyphae is abnormal." ;
rdfs:subClassOf obo:PHIPO_0001214 .
obo:GO_0044282 a rdfs:Class ;
rdfs:label "small molecule catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0044281 .
obo:CHEBI_76710 a rdfs:Class ;
rdfs:label "EC 4.* (lyase) inhibitor" ;
rdfs:comment "An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C‒C, C‒O, C‒N and other bonds by other means than by hydrolysis or oxidation." ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:CHEBI_192484 a rdfs:Class ;
rdfs:label "ciprofloxacin zwitterion" ;
rdfs:comment "A zwitterion formed from ciprofloxacin by transfer of a proton from the carboxy to the amino group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:UBERON_0003567 a rdfs:Class ;
rdfs:label "abdomen connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of an abdomen [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003838 .
obo:GO_0099528 a rdfs:Class ;
rdfs:label "G protein-coupled neurotransmitter receptor activity" ;
rdfs:comment "Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." ;
rdfs:subClassOf obo:GO_0004930 , obo:GO_0030594 .
obo:UBERON_0003902 a rdfs:Class ;
rdfs:label "retinal neural layer" ;
rdfs:comment "The part of the retina that contains neurons and photoreceptor cells[GO]." ;
rdfs:subClassOf obo:UBERON_0001781 , obo:UBERON_0004121 .
obo:GO_0097712 a rdfs:Class ;
rdfs:label "trans-Golgi to periciliary membrane compartment transport" ;
rdfs:comment "The directed movement of substances from the trans-Golgi network to the periciliary membrane compartment, the specialized region of the plasma membrane surrounding the base of the cilium including the ciliary pocket, via vesicle-mediated transport." ;
rdfs:subClassOf obo:GO_0006893 .
obo:GO_1903697 a rdfs:Class ;
rdfs:label "negative regulation of microvillus assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly." ;
rdfs:subClassOf obo:GO_0032534 , obo:GO_0065007 , obo:GO_0120033 .
obo:GO_0086103 a rdfs:Class ;
rdfs:label "G protein-coupled receptor signaling pathway involved in heart process" ;
rdfs:comment "An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart." ;
rdfs:subClassOf obo:GO_0007186 .
obo:UBERON_0004761 a rdfs:Class ;
rdfs:label "cartilaginous neurocranium" ;
rdfs:comment "The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]." ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:CL_0000575 a rdfs:Class ;
rdfs:label "corneal epithelial cell" ;
rdfs:comment "An epithelial cell of the cornea." ;
rdfs:subClassOf obo:CL_0000076 , obo:CL_0002159 .
obo:GO_0035592 a rdfs:Class ;
rdfs:label "establishment of protein localization to extracellular region" ;
rdfs:comment "The directed movement of a protein to a specific location within the extracellular region." ;
rdfs:subClassOf obo:GO_0045184 , obo:GO_0071692 .
obo:GO_0021703 a rdfs:Class ;
rdfs:label "locus ceruleus development" ;
rdfs:comment "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048857 .
obo:UBERON_0003911 a rdfs:Class ;
rdfs:label "choroid plexus epithelium" ;
rdfs:comment "The epithelial component of the choroid plexus. Consists of cuboidal epithelial cells surrounding a core of capillaries and loose connective tissue." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:CHEBI_76878 a rdfs:Class ;
rdfs:label "EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor" ;
rdfs:comment "An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*)." ;
rdfs:subClassOf obo:CHEBI_76661 .
obo:GO_0003341 a rdfs:Class ;
rdfs:label "cilium movement" ;
rdfs:comment "The directed, self-propelled movement of a cilium." ;
rdfs:subClassOf obo:GO_0007018 .
obo:GO_2001049 a rdfs:Class ;
rdfs:label "regulation of tendon cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of tendon cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:PATO_0002064 a rdfs:Class ;
rdfs:label "fenestrated" ;
rdfs:comment "A structure quality inhering in a bearer by virtue of the bearer's delimited by a surface with holes." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:PHIPO_0000356 a rdfs:Class ;
rdfs:label "obsolete abnormal penetration of host by pathogen" ;
rdfs:comment "A pathogen growth with host phenotype in which the pathogen penetration into the host is abnormal (i.e different than wild-type)." .
obo:CHEBI_25212 a rdfs:Class ;
rdfs:label "metabolite" ;
rdfs:comment "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." ;
rdfs:subClassOf obo:CHEBI_52206 .
obo:GO_0048102 a rdfs:Class ;
rdfs:label "autophagic cell death" ;
rdfs:comment "A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells." ;
rdfs:subClassOf obo:GO_0012501 .
obo:GO_0061052 a rdfs:Class ;
rdfs:label "negative regulation of cell growth involved in cardiac muscle cell development" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." ;
rdfs:subClassOf obo:GO_0010614 , obo:GO_0030308 , obo:GO_0051154 , obo:GO_0055022 , obo:GO_0061050 , obo:GO_0065007 .
obo:GO_1905652 a rdfs:Class ;
rdfs:label "negative regulation of artery morphogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905651 , obo:GO_2000181 .
obo:GO_1901509 a rdfs:Class ;
rdfs:label "regulation of endothelial tube morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905330 .
obo:GO_0098917 a rdfs:Class ;
rdfs:label "retrograde trans-synaptic signaling" ;
rdfs:comment "Cell-cell signaling from post to pre-synapse, across the synaptic cleft." ;
rdfs:subClassOf obo:GO_0099537 .
obo:GO_0043271 a rdfs:Class ;
rdfs:label "negative regulation of monoatomic ion transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0043269 , obo:GO_0051051 , obo:GO_0065007 .
obo:GO_1902116 a rdfs:Class ;
rdfs:label "negative regulation of organelle assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0065007 , obo:GO_1902115 .
obo:CHEBI_35213 a rdfs:Class ;
rdfs:label "cyclodepsipeptide" ;
rdfs:comment "A depsipeptide in which the amino and hydroxy carboxylic acid residues are connected in a ring." ;
rdfs:subClassOf obo:CHEBI_23643 , obo:CHEBI_25000 .
obo:CHEBI_33253 a rdfs:Class ;
rdfs:label "nucleon" ;
rdfs:comment "Heavy nuclear particle: proton or neutron." ;
rdfs:subClassOf obo:CHEBI_36339 , obo:CHEBI_36347 .
obo:GO_0002085 a rdfs:Class ;
rdfs:label "inhibition of neuroepithelial cell differentiation" ;
rdfs:comment "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0030857 , obo:GO_0045995 , obo:GO_0048505 , obo:GO_0065007 .
obo:PATO_0002009 a rdfs:Class ;
rdfs:label "branchiness" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:PR_000001954 a rdfs:Class ;
rdfs:label "tumor necrosis factor receptor superfamily member 11A" ;
rdfs:comment "A protein that is a translation product of the human TNFRSF11A gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0005472 a rdfs:Class ;
rdfs:label "right vitelline vein" ;
rdfs:comment "A vitelline vein that is in the right side of a multicellular organism." ;
rdfs:subClassOf obo:UBERON_0005487 , obo:UBERON_0015212 .
obo:GO_0032275 a rdfs:Class ;
rdfs:label "luteinizing hormone secretion" ;
rdfs:comment "The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary." ;
rdfs:subClassOf obo:GO_0032274 .
obo:GO_1904676 a rdfs:Class ;
rdfs:label "negative regulation of somatic stem cell division" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division." ;
rdfs:subClassOf obo:GO_0051782 , obo:GO_0065007 , obo:GO_1904675 .
obo:GO_0046828 a rdfs:Class ;
rdfs:label "regulation of RNA import into nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus." ;
rdfs:subClassOf obo:GO_0032239 , obo:GO_0046822 , obo:GO_0065007 .
obo:GO_1901164 a rdfs:Class ;
rdfs:label "negative regulation of trophoblast cell migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration." ;
rdfs:subClassOf obo:GO_0030336 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1901163 , obo:GO_2000242 .
obo:GO_0031076 a rdfs:Class ;
rdfs:label "embryonic camera-type eye development" ;
rdfs:comment "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0043010 , obo:GO_0048568 .
obo:GO_0031644 a rdfs:Class ;
rdfs:label "regulation of nervous system process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." ;
rdfs:subClassOf obo:GO_0044057 , obo:GO_0065007 .
obo:UBERON_0001019 a rdfs:Class ;
rdfs:label "nerve fasciculus" ;
rdfs:comment "A slender neuron projection bundle[FBbt]; A bundle of anatomical fibers, as of muscle or nerve (American Heritage Dictionary 4th ed)." ;
rdfs:subClassOf obo:UBERON_0000122 .
obo:CHEBI_51446 a rdfs:Class ;
rdfs:label "organic divalent group" ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:CHEBI_28868 a rdfs:Class ;
rdfs:label "fatty acid anion" ;
rdfs:comment "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid." ;
rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_35757 .
obo:UBERON_0008909 a rdfs:Class ;
rdfs:label "perichordal bone" ;
rdfs:comment "Bone element that is adjacent to the notochord." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0012075 .
obo:CHEBI_31927 a rdfs:Class ;
rdfs:label "nystatin A3" ;
rdfs:subClassOf obo:CHEBI_59676 .
obo:CHEBI_35561 a rdfs:Class ;
rdfs:label "3H-1,2,4-triazole" ;
rdfs:subClassOf obo:CHEBI_35560 .
obo:GO_1905872 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to cell leading edge" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903828 , obo:GO_1905871 .
obo:GO_0061973 a rdfs:Class ;
rdfs:label "membrane bone morphogenesis" ;
rdfs:comment "The process in which bone which forms deep in the organism are generated and organized." ;
rdfs:subClassOf obo:GO_0060349 .
obo:GO_0032410 a rdfs:Class ;
rdfs:label "negative regulation of transporter activity" ;
rdfs:comment "Any process that stops or reduces the activity of a transporter." ;
rdfs:subClassOf obo:GO_0044092 , obo:GO_0051051 , obo:GO_0065007 .
obo:PHIPO_0000952 a rdfs:Class ;
rdfs:label "abolished pathogen growth within host"@en ;
rdfs:comment "A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is abolished (it was present as is now absent)." ;
rdfs:subClassOf obo:PHIPO_0000363 .
obo:GO_0050729 a rdfs:Class ;
rdfs:label "positive regulation of inflammatory response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the inflammatory response." ;
rdfs:subClassOf obo:GO_0031349 , obo:GO_0032103 , obo:GO_0050727 , obo:GO_0065007 .
obo:GO_0051046 a rdfs:Class ;
rdfs:label "regulation of secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:GO_0000323 a rdfs:Class ;
rdfs:label "lytic vacuole" ;
rdfs:comment "A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases." ;
rdfs:subClassOf obo:GO_0005773 .
obo:UBERON_0010161 a rdfs:Class ;
rdfs:label "lumen of blood vessel" ;
rdfs:comment "An anatomical cavity that surrounded_by a blood vessel." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0070585 a rdfs:Class ;
rdfs:label "protein localization to mitochondrion" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within the mitochondrion." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033365 .
obo:GO_1903551 a rdfs:Class ;
rdfs:label "regulation of extracellular exosome assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902115 .
obo:CHEBI_77941 a rdfs:Class ;
rdfs:label "EC 3.5.1.4 (amidase) inhibitor" ;
rdfs:comment "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." ;
rdfs:subClassOf obo:CHEBI_76807 .
obo:GO_0071764 a rdfs:Class ;
rdfs:label "nuclear outer membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0071763 .
obo:CHEBI_35862 a rdfs:Class ;
rdfs:label "bacitracin A" ;
rdfs:comment "A homodetic cyclic peptide consisting of (4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid attached head-to-tail to L-leucyl,D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl. D-aspartyl and L-asparaginyl residues coupled in sequence and cyclised by condensation of the side-chain amino group of the L-lysyl residue with the C-terminal carboxylic acid group. It is the major component of bacitracin." ;
rdfs:subClassOf obo:CHEBI_15841 , obo:CHEBI_24613 .
obo:GO_0048662 a rdfs:Class ;
rdfs:label "negative regulation of smooth muscle cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0048660 , obo:GO_0065007 .
obo:UBERON_0004904 a rdfs:Class ;
rdfs:label "neuron projection bundle connecting eye with brain" ;
rdfs:comment "A neuron projection bundle that connects the retina or its analog in the eye with the brain. This includes the vertebrate optic nerve (not truly a nerve) as well as analogous structures such as the Bolwig nerve in Drosophila." ;
rdfs:subClassOf obo:UBERON_0000122 .
obo:UBERON_0007846 a rdfs:Class ;
rdfs:label "dense regular connective tissue" ;
rdfs:comment "Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts)." ;
rdfs:subClassOf obo:UBERON_0007845 , obo:UBERON_0011823 .
obo:CHEBI_17925 a rdfs:Class ;
rdfs:label "alpha-D-glucose" ;
rdfs:comment "D-Glucopyranose having α-configuration at the anomeric centre." ;
rdfs:subClassOf obo:CHEBI_4167 .
obo:GO_0003157 a rdfs:Class ;
rdfs:label "endocardium development" ;
rdfs:comment "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_76816 a rdfs:Class ;
rdfs:label "EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor" ;
rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category." ;
rdfs:subClassOf obo:CHEBI_76668 .
obo:UBERON_0000930 a rdfs:Class ;
rdfs:label "stomodeum" ;
rdfs:comment "Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity." ;
rdfs:subClassOf obo:UBERON_0013522 .
obo:CL_2000047 a rdfs:Class ;
rdfs:label "brainstem motor neuron" ;
rdfs:comment "Any motor neuron that is part of a brainstem." ;
rdfs:subClassOf obo:CL_0000100 , obo:CL_2000029 .
obo:CL_0000568 a rdfs:Class ;
rdfs:label "amine precursor uptake and decarboxylation cell" ;
rdfs:comment "A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell." ;
rdfs:subClassOf obo:CL_0000165 .
obo:GO_1902037 a rdfs:Class ;
rdfs:label "negative regulation of hematopoietic stem cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901533 , obo:GO_1902036 , obo:GO_2000737 .
obo:NCBITaxon_7898 a rdfs:Class ;
rdfs:label "Actinopterygii" ;
rdfs:subClassOf obo:NCBITaxon_117571 .
obo:UBERON_0004921 a rdfs:Class ;
rdfs:label "subdivision of digestive tract" ;
rdfs:comment "A proximal-distal subdivision of the digestive tract." ;
rdfs:subClassOf obo:UBERON_0013522 .
obo:GO_1903225 a rdfs:Class ;
rdfs:label "negative regulation of endodermal cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0065007 , obo:GO_1903224 .
obo:CHEBI_59793 a rdfs:Class ;
rdfs:label "monothioacetal" ;
rdfs:comment "A thioacetal having the structure R2C(OR')(SR'). The term includes monothioketals, R ≠ H, as a subclass." ;
rdfs:subClassOf obo:CHEBI_59792 .
obo:GO_0045650 a rdfs:Class ;
rdfs:label "negative regulation of macrophage differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation." ;
rdfs:subClassOf obo:GO_0002762 , obo:GO_0045649 , obo:GO_0065007 .
obo:CL_4042020 a rdfs:Class ;
rdfs:label "beta2-tanycyte"@en ;
rdfs:comment "A type of tanycyte located in the floor of third ventricle and the infindibular recess. This tanycyte has an elongated morphology with multiple microvilli extending medially and ventrally to the median eminence, contacting the pial surface and blood vessels. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH)." ;
rdfs:subClassOf obo:CL_0002085 .
obo:GO_0071676 a rdfs:Class ;
rdfs:label "negative regulation of mononuclear cell migration" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0002686 , obo:GO_0065007 , obo:GO_0071675 .
obo:GO_0052547 a rdfs:Class ;
rdfs:label "regulation of peptidase activity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins." ;
rdfs:subClassOf obo:GO_0030162 , obo:GO_0051336 , obo:GO_0065007 .
obo:PHIPO_0000450 a rdfs:Class ;
rdfs:label "normal pathogen peptidase activity"@en ;
rdfs:comment "A single species molecular function phenotype in which the observed rate of a peptidase activity is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000433 .
obo:UBERON_0004234 a rdfs:Class ;
rdfs:label "iris smooth muscle" ;
rdfs:comment "A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0003386 .
obo:PHIPO_0001251 a rdfs:Class ;
rdfs:label "host defense-induced protein present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the host protein usually present during infection is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001262 .
obo:PATO_0045080 a rdfs:Class ;
rdfs:label "normal virulence" ;
rdfs:comment "A virulence which is relatively normal or average" ;
rdfs:subClassOf obo:PATO_0002146 , obo:PATO_0045001 .
obo:PHIPO_0000840 a rdfs:Class ;
rdfs:label "sensitive to dicloxacillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to dicloxacillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:UBERON_0000371 a rdfs:Class ;
rdfs:label "syncytiotrophoblast" ;
rdfs:comment "Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated)." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_1904626 a rdfs:Class ;
rdfs:label "positive regulation of glycine secretion, neurotransmission" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission." ;
rdfs:subClassOf obo:GO_0001956 , obo:GO_0032892 , obo:GO_0051957 , obo:GO_0060094 , obo:GO_0065007 , obo:GO_1904624 .
obo:CHEBI_37912 a rdfs:Class ;
rdfs:label "hydroxycoumarin" ;
rdfs:comment "Any coumarin carrying at least one hydroxy substituent." ;
rdfs:subClassOf obo:CHEBI_23403 .
obo:CHEBI_27881 a rdfs:Class ;
rdfs:label "resveratrol" ;
rdfs:comment "A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups." ;
rdfs:subClassOf obo:CHEBI_26195 , obo:CHEBI_33572 , obo:CHEBI_36027 .
obo:PCL_0010001 a rdfs:Class .
obo:CHEBI_58945 a rdfs:Class ;
rdfs:label "organophosphate oxoanion" ;
rdfs:comment "An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_26079 .
obo:PHIPO_0001381 a rdfs:Class ;
rdfs:label "sensitive to iron"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to iron. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0030900 a rdfs:Class ;
rdfs:label "forebrain development" ;
rdfs:comment "The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_1903431 a rdfs:Class ;
rdfs:label "positive regulation of cell maturation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell maturation." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0065007 , obo:GO_1903429 .
obo:CL_1001474 a rdfs:Class ;
rdfs:label "medium spiny neuron" ;
rdfs:comment "An inhibitory, GABAergic projection neuron in the striatum that integrates glutamatergic signals arising from the cerebral cortex and thalamus." ;
rdfs:subClassOf obo:CL_0000617 , obo:CL_4023035 .
obo:CHEBI_60911 a rdfs:Class ;
rdfs:label "racemate" ;
rdfs:comment "A racemate is an equimolar mixture of a pair of enantiomers." ;
rdfs:subClassOf obo:CHEBI_60004 .
obo:UBERON_0037094 a rdfs:Class ;
rdfs:label "wall of common carotid artery" ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0000415 .
obo:UBERON_0007122 a rdfs:Class ;
rdfs:label "pharyngeal pouch 1" ;
rdfs:comment "A pharyngeal pouch that is between pharyngeal arches 1 and 2." ;
rdfs:subClassOf obo:UBERON_0004117 .
obo:GO_0051150 a rdfs:Class ;
rdfs:label "regulation of smooth muscle cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051147 , obo:GO_0065007 .
obo:UBERON_0005382 a rdfs:Class ;
rdfs:label "dorsal striatum" ;
rdfs:comment "Dorsal components of the striatum comprising the caudate nucleus and the putamen, in species that have distinct nuclei; the caudoputamen in species which don't." ;
rdfs:subClassOf obo:UBERON_0011300 .
obo:CHEBI_17883 a rdfs:Class ;
rdfs:label "hydrogen chloride" ;
rdfs:comment "A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms." ;
rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18140 , obo:CHEBI_23117 , obo:CHEBI_37176 .
obo:PHIPO_0001341 a rdfs:Class ;
rdfs:label "normal growth on thiabendazole"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to thiabendazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:BFO_0000016 a rdfs:Class ;
rdfs:label "disposition"@en ;
rdfs:subClassOf obo:BFO_0000017 .
obo:PHIPO_0000589 a rdfs:Class ;
rdfs:label "resistance to mupirocin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to mupirocin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0043434 a rdfs:Class ;
rdfs:label "response to peptide hormone" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." ;
rdfs:subClassOf obo:GO_0009725 , obo:GO_0050896 , obo:GO_1901698 , obo:GO_1901700 .
obo:GO_0045759 a rdfs:Class ;
rdfs:label "negative regulation of action potential" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0065007 , obo:GO_0098900 .
obo:GO_0030435 a rdfs:Class ;
rdfs:label "sporulation resulting in formation of a cellular spore" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction." ;
rdfs:subClassOf obo:GO_0043934 , obo:GO_0048646 .
obo:GO_0060788 a rdfs:Class ;
rdfs:label "ectodermal placode formation" ;
rdfs:comment "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0043184 a rdfs:Class ;
rdfs:label "vascular endothelial growth factor receptor 2 binding" ;
rdfs:comment "Binding to a vascular endothelial growth factor receptor 2." ;
rdfs:subClassOf obo:GO_0005172 , obo:GO_0005488 .
obo:PHIPO_0000712 a rdfs:Class ;
rdfs:label "resistance to cefazolin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cefazolin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0015711 a rdfs:Class ;
rdfs:label "organic anion transport" ;
rdfs:comment "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." ;
rdfs:subClassOf obo:GO_0006810 .
obo:UBERON_0006514 a rdfs:Class ;
rdfs:label "pallidum" ;
rdfs:comment "Part of what are called the basal ganglia of the brain which consist of the globus pallidus and the ventral pallidum." ;
rdfs:subClassOf obo:UBERON_0003528 .
obo:GO_1905475 a rdfs:Class ;
rdfs:label "regulation of protein localization to membrane" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to membrane." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:UBERON_0003715 a rdfs:Class ;
rdfs:label "splanchnic nerve" ;
rdfs:comment "The major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia." ;
rdfs:subClassOf obo:UBERON_0001021 , obo:UBERON_0034729 .
obo:GO_0050764 a rdfs:Class ;
rdfs:label "regulation of phagocytosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." ;
rdfs:subClassOf obo:GO_0030100 , obo:GO_0065007 .
obo:PHIPO_0000086 a rdfs:Class ;
rdfs:label "obsolete normal asexual spore motility" .
obo:CHEBI_24436 a rdfs:Class ;
rdfs:label "guanidines" ;
rdfs:comment "Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R1R2N)(R3R4N)C=N-R5 and are related structurally to amidines and ureas." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:UBERON_0013140 a rdfs:Class ;
rdfs:label "systemic vein" ;
rdfs:comment "Any vein within the general circulation that transports blood back to the right atrium of the heart." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:UBERON_0003071 a rdfs:Class ;
rdfs:label "eye primordium" ;
rdfs:comment "Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0001048 , obo:UBERON_0005291 , obo:UBERON_0006598 .
obo:GO_0000278 a rdfs:Class ;
rdfs:label "mitotic cell cycle" ;
rdfs:comment "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." ;
rdfs:subClassOf obo:GO_0007049 .
obo:UBERON_0003887 a rdfs:Class ;
rdfs:label "intraembryonic coelom" ;
rdfs:comment "The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0048589 a rdfs:Class ;
rdfs:label "developmental growth" ;
rdfs:comment "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." ;
rdfs:subClassOf obo:GO_0040007 .
obo:GO_1902532 a rdfs:Class ;
rdfs:label "negative regulation of intracellular signal transduction" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." ;
rdfs:subClassOf obo:GO_0009968 , obo:GO_0065007 , obo:GO_1902531 .
obo:GO_0070231 a rdfs:Class ;
rdfs:label "T cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0070227 .
obo:GO_0008292 a rdfs:Class ;
rdfs:label "acetylcholine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline." ;
rdfs:subClassOf obo:GO_0008291 , obo:GO_0009058 .
obo:GO_0008015 a rdfs:Class ;
rdfs:label "blood circulation" ;
rdfs:comment "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." ;
rdfs:subClassOf obo:GO_0003013 .
obo:UBERON_0005614 a rdfs:Class ;
rdfs:label "lens anterior epithelium" ;
rdfs:comment "A layer of cuboidal epithelial cells bounded anteriorly by the capsule of the lens and posteriorly by the lens cortex." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0001803 , obo:UBERON_0010371 .
obo:GO_0001667 a rdfs:Class ;
rdfs:label "ameboidal-type cell migration" ;
rdfs:comment "Cell migration that is accomplished by extension and retraction of a pseudopodium." ;
rdfs:subClassOf obo:GO_0016477 .
obo:GO_0002604 a rdfs:Class ;
rdfs:label "regulation of dendritic cell antigen processing and presentation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002577 , obo:GO_0065007 .
obo:CL_4301576 a rdfs:Class ;
rdfs:label "CB PLI Gly-Gaba_3 Purkinje layer interneuron (Mmus)" ;
rdfs:comment "A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pax2 (Mmus), C1ql3 (Mmus), Tfap2b (Mmus), Gabrb1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1146 CB PLI Gly-Gaba_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300349 .
obo:PHIPO_0000739 a rdfs:Class ;
rdfs:label "sensitive to latrunculin A"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to latrunculin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000392 a rdfs:Class ;
rdfs:label "sensitive to thiophanate methyl"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to thiophanate methyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0034719 a rdfs:Class ;
rdfs:label "lip taste bud" ;
rdfs:comment "A taste bud that is located on a lip." ;
rdfs:subClassOf obo:UBERON_0001727 , obo:UBERON_0013765 .
obo:CHEBI_42485 a rdfs:Class ;
rdfs:label "formyl group" ;
rdfs:subClassOf obo:CHEBI_27207 .
obo:GO_1902742 a rdfs:Class ;
rdfs:label "apoptotic process involved in development" ;
rdfs:comment "Any apoptotic process that is involved in anatomical structure development." ;
rdfs:subClassOf obo:GO_0006915 .
obo:UBERON_0001637 a rdfs:Class ;
rdfs:label "artery" ;
rdfs:comment "An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]." ;
rdfs:subClassOf obo:UBERON_0003509 .
obo:CHEBI_61951 a rdfs:Class ;
rdfs:label "microtubule-destabilising agent" ;
rdfs:comment "Any substance that interacts with tubulin to inhibit polymerisation of microtubules." ;
rdfs:subClassOf obo:CHEBI_60832 , obo:CHEBI_64911 .
obo:CL_2000027 a rdfs:Class ;
rdfs:label "cerebellar basket cell" ;
rdfs:comment "A GABAergic inhibitory interneuron located in the molecular layer of the cerebellar cortex. It projects axons that form specialized synaptic structures around Purkinje cells, including pericellular baskets, which wrap around the Purkinje cell soma, and the pinceau: a brush-like terminal that contacts the initial segment of the Purkinje cell axon. The basket cell modulates Purkinje cell activity through both chemical (GABAergic) and non-synaptic (ephaptic) mechanisms. It is arranged in sagittal rows that align with Purkinje cell zones, contributing to the cerebellum's modular and topographically organized architecture. It plays an essential role in regulating motor coordination and potentially cognitive functions." ;
rdfs:subClassOf obo:CL_0000118 , obo:CL_4042035 .
obo:UBERON_0000165 a rdfs:Class ;
rdfs:label "mouth" ;
rdfs:comment "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." ;
rdfs:subClassOf obo:UBERON_0004921 .
obo:BSPO_0001106 a rdf:Property ;
rdfs:range .
obo:UBERON_0010221 a rdfs:Class ;
rdfs:label "laryngeal associated mesenchyme" ;
rdfs:comment "Many sources say: thyroid cartilage from arch 4 other laryngeal cartilage (cricoid/arytenoid) from 6?" ;
rdfs:subClassOf obo:UBERON_0007524 .
obo:CL_0000552 a rdfs:Class ;
rdfs:label "orthochromatic erythroblast" ;
rdfs:comment "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated." ;
rdfs:subClassOf obo:CL_0000765 .
obo:CHEBI_18208 a rdfs:Class ;
rdfs:label "benzylpenicillin" ;
rdfs:comment "A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_88187 .
obo:GO_0061951 a rdfs:Class ;
rdfs:label "establishment of protein localization to plasma membrane" ;
rdfs:comment "The directed movement of a protein to a specific location in a plasma membrane." ;
rdfs:subClassOf obo:GO_0045184 , obo:GO_0072659 , obo:GO_0090150 .
obo:UBERON_0007641 a rdfs:Class ;
rdfs:label "trigeminal nuclear complex" ;
rdfs:comment "The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]." ;
rdfs:subClassOf obo:UBERON_0007245 .
obo:IAO_0000030 a rdfs:Class ;
rdfs:label "information content entity"@en ;
rdfs:subClassOf obo:BFO_0000031 .
obo:CHEBI_63248 a rdfs:Class ;
rdfs:label "oxidising agent" ;
rdfs:comment "A substance that removes electrons from another reactant in a redox reaction." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:CHEBI_51683 a rdfs:Class ;
rdfs:label "methoxybenzenes" ;
rdfs:comment "Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_35618 .
obo:CHEBI_27644 a rdfs:Class ;
rdfs:label "chlortetracycline" ;
rdfs:comment "A member of the class of tetracyclines with formula C22H23ClN2O8 isolated from Streptomyces aureofaciens." ;
rdfs:subClassOf obo:CHEBI_139592 , obo:CHEBI_26895 , obo:CHEBI_29347 , obo:CHEBI_50996 , obo:CHEBI_83403 .
obo:GO_1904820 a rdfs:Class ;
rdfs:label "peritoneum development" ;
rdfs:comment "The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_1904817 .
obo:GO_2000110 a rdfs:Class ;
rdfs:label "negative regulation of macrophage apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process." ;
rdfs:subClassOf obo:GO_0033033 , obo:GO_0065007 , obo:GO_2000107 , obo:GO_2000109 .
obo:PATO_0000911 a rdfs:Class ;
rdfs:label "decreased rate" ;
rdfs:comment "A rate which is relatively low." ;
rdfs:subClassOf obo:PATO_0000161 , obo:PATO_0002302 .
obo:GO_0006606 a rdfs:Class ;
rdfs:label "protein import into nucleus" ;
rdfs:comment "The directed movement of a protein from the cytoplasm to the nucleus." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0006886 , obo:GO_0034504 , obo:GO_0051170 , obo:GO_0072594 .
obo:GO_1904818 a rdfs:Class ;
rdfs:label "visceral peritoneum development" ;
rdfs:comment "The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_59066 a rdfs:Class ;
rdfs:label "oxolinate" ;
rdfs:comment "Conjugate base of oxolinic acid." ;
rdfs:subClassOf obo:CHEBI_38773 .
obo:PATO_0045050 a rdfs:Class ;
rdfs:label "normal size" ;
rdfs:comment "A size quality which is relatively normal or average" ;
rdfs:subClassOf obo:PATO_0000117 , obo:PATO_0045001 .
obo:NCBITaxon_32443 a rdfs:Class ;
rdfs:label "Teleostei" ;
rdfs:subClassOf obo:NCBITaxon_41665 .
obo:UBERON_0035814 a rdfs:Class ;
rdfs:label "pericardial fat" ;
rdfs:comment "The sum of epicardial and paracardial fat deposits." ;
rdfs:subClassOf obo:UBERON_0001013 , obo:UBERON_0035818 .
obo:CL_0000240 a rdfs:Class ;
rdfs:label "stratified squamous epithelial cell" ;
rdfs:comment "A stratified epithelial cell that is part of squamous epithelium, characterized by multiple layers of cells. The basal layer is directly attached to the basement membrane and the apical layer consists of flattened squamous cells. This provides a protective barrier, commonly found in areas subject to abrasion, such as the skin, oral cavity, and esophagus." ;
rdfs:subClassOf obo:CL_0000076 , obo:CL_0000079 .
obo:GO_0017111 a rdfs:Class ;
rdfs:label "ribonucleoside triphosphate phosphatase activity" ;
rdfs:comment "Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate." ;
rdfs:subClassOf obo:GO_0016462 .
obo:GO_0098793 a rdfs:Class ;
rdfs:label "presynapse" ;
rdfs:comment "The part of a synapse that is part of the presynaptic cell." ;
rdfs:subClassOf obo:GO_0110165 .
obo:PHIPO_0000059 a rdfs:Class ;
rdfs:label "normal number of asexual spores"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of asexual spores is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000080 .
obo:GO_0021602 a rdfs:Class ;
rdfs:label "cranial nerve morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PATO_0000025 a rdfs:Class ;
rdfs:label "composition" ;
rdfs:comment "A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:UBERON_0018254 a rdfs:Class ;
rdfs:label "skeletal musculature" ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:UBERON_0005498 a rdfs:Class ;
rdfs:label "primitive heart tube" ;
rdfs:comment "Multi-tissue structure that arises from the heart rudiment and will become the heart tube." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0004120 .
obo:CHEBI_71339 a rdfs:Class ;
rdfs:label "novobiocin(1-)" ;
rdfs:comment "An organic anion that is the conjugate base of novobiocin." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:UBERON_0035398 a rdfs:Class ;
rdfs:label "branch of external carotid artery" ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:PHIPO_0001173 a rdfs:Class ;
rdfs:label "pathogen modulation of host process phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which a pathogen effects a change in the structure or processes of its host organism (GO:0044003)." ;
rdfs:subClassOf obo:PHIPO_0000510 .
obo:UBERON_0011825 a rdfs:Class ;
rdfs:label "loose connective tissue" ;
rdfs:comment "Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue." ;
rdfs:subClassOf obo:UBERON_0011821 .
obo:GO_0006796 a rdfs:Class ;
rdfs:label "phosphate-containing compound metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." ;
rdfs:subClassOf obo:GO_0008152 .
obo:UBERON_0001824 a rdfs:Class ;
rdfs:label "mucosa of larynx" ;
rdfs:comment "The mucous lining of the larynx, which is composed of squamous epithelium in the upper larynx and ciliated columnar epithelium in the lower larynx." ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0004785 .
obo:UBERON_0002925 a rdfs:Class ;
rdfs:label "trigeminal nucleus" ;
rdfs:comment "A nucleus of brain that is part of a trigeminal nuclear complex." ;
rdfs:subClassOf obo:UBERON_0000126 , obo:UBERON_0002308 .
obo:GO_1903120 a rdfs:Class ;
rdfs:label "protein localization to actin filament bundle" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, the location of an actin filament bundle." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_1903119 .
obo:CHEBI_27369 a rdfs:Class ;
rdfs:label "zwitterion" ;
rdfs:comment "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." ;
rdfs:subClassOf obo:CHEBI_51151 .
obo:PHIPO_0000974 a rdfs:Class ;
rdfs:label "decreased unicellular population growth"@en ;
rdfs:comment "A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is lesser than normal." ;
rdfs:subClassOf obo:PHIPO_0000414 , obo:PHIPO_0000929 .
obo:GO_0003217 a rdfs:Class ;
rdfs:label "cardiac right atrium formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts." ;
rdfs:subClassOf obo:GO_0003210 , obo:GO_0048646 .
obo:CHEBI_23424 a rdfs:Class ;
rdfs:label "cyanides" ;
rdfs:comment "Salts and C-organyl derivatives of hydrogen cyanide, HC≡N." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:GO_0019777 a rdfs:Class ;
rdfs:label "Atg12 transferase activity" ;
rdfs:comment "Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages." ;
rdfs:subClassOf obo:GO_0019787 .
obo:PHIPO_0000640 a rdfs:Class ;
rdfs:label "resistance to sparfloxacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to sparfloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0004288 a rdfs:Class ;
rdfs:label "skeleton" ;
rdfs:comment "Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body." ;
rdfs:subClassOf obo:UBERON_0034925 .
obo:UBERON_0005359 a rdfs:Class ;
rdfs:label "spinal cord ependyma" ;
rdfs:comment "The ependymal cell layer that lines the spinal cord." ;
rdfs:subClassOf obo:UBERON_0004670 .
obo:CL_0000123 a rdfs:Class ;
rdfs:label "neuron associated cell (sensu Vertebrata)" ;
rdfs:subClassOf obo:CL_0000095 .
obo:GO_0034350 a rdfs:Class ;
rdfs:label "regulation of glial cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:CL_0000642 a rdfs:Class ;
rdfs:label "folliculostellate cell" ;
rdfs:comment "An agranular supporting cell of the anterior pituitary (adenohypophysis) that is characterized by a star-like morphology and ability to form follicles. Folliculostellate cells communicate with each other and with endocrine cells via gap junctions." ;
rdfs:subClassOf obo:CL_0000630 , obo:CL_2000004 .
obo:CLM_1000082 a rdfs:Class ;
rdfs:label "NS forest marker set of sst GABAergic interneuron (Human neocortex)." ;
rdfs:subClassOf obo:SO_0001260 .
obo:GO_0005761 a rdfs:Class ;
rdfs:label "mitochondrial ribosome" ;
rdfs:comment "A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes." ;
rdfs:subClassOf obo:GO_0000313 , obo:GO_0005840 .
obo:UBERON_0005631 a rdfs:Class ;
rdfs:label "extraembryonic membrane" ;
rdfs:comment "Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo." ;
rdfs:subClassOf obo:UBERON_0000158 .
obo:GO_0043011 a rdfs:Class ;
rdfs:label "myeloid dendritic cell differentiation" ;
rdfs:comment "The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin." ;
rdfs:subClassOf obo:GO_0001773 , obo:GO_0002573 , obo:GO_0030154 , obo:GO_0097028 .
obo:GO_1903348 a rdfs:Class ;
rdfs:label "positive regulation of bicellular tight junction assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of tight junction assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901890 , obo:GO_2000810 .
obo:GO_1904698 a rdfs:Class ;
rdfs:label "negative regulation of acinar cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation." ;
rdfs:subClassOf obo:GO_0050680 , obo:GO_0065007 , obo:GO_1904697 .
obo:CHEBI_82892 a rdfs:Class ;
rdfs:label "1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole" ;
rdfs:comment "A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group." ;
rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_24780 , obo:CHEBI_25698 .
obo:GO_0032127 a rdfs:Class ;
rdfs:label "dense core granule membrane" ;
rdfs:comment "The lipid bilayer surrounding a dense core granule." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0030667 .
obo:GO_0045666 a rdfs:Class ;
rdfs:label "positive regulation of neuron differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuron differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0045664 , obo:GO_0065007 .
obo:PR_P56528 a rdfs:Class ;
rdfs:label "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (mouse)" ;
rdfs:comment "An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001408 , obo:PR_000029032 .
obo:UBERON_0003833 a rdfs:Class ;
rdfs:label "abdominal segment muscle" ;
rdfs:comment "A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001774 , obo:UBERON_0005173 , obo:UBERON_0014892 .
obo:GO_0031143 a rdfs:Class ;
rdfs:label "pseudopodium" ;
rdfs:comment "A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding." ;
rdfs:subClassOf obo:GO_0120025 .
obo:GO_0002471 a rdfs:Class ;
rdfs:label "monocyte antigen processing and presentation" ;
rdfs:comment "The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." ;
rdfs:subClassOf obo:GO_0019882 .
obo:PHIPO_0000128 a rdfs:Class ;
rdfs:label "normal asexual spore morphology"@en ;
rdfs:comment "A reproductive phenotype where the morphology of the asexual spore is normal (FAO:0000023). The product of mitosis." ;
rdfs:subClassOf obo:PHIPO_0000045 .
obo:PHIPO_0000879 a rdfs:Class ;
rdfs:label "sensitive to itraconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to itraconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CL_3000004 a rdfs:Class ;
rdfs:label "peripheral sensory neuron" ;
rdfs:comment "A neuron type that is located in a peripheral nervous system and it transmits sensory information from the peripheral (PNS) to the central nervous system (CNS). A sensory neuron converts physical (light, sound, touch) or chemical (such as taste and smell) stimuli into an electrical signal through a process known as sensory transduction. The function of a sensory neuron is to carry informations from the external environment and internal body conditions to the central nervous system for further processing." ;
rdfs:subClassOf obo:CL_0000101 , obo:CL_2000032 .
obo:CHEBI_23849 a rdfs:Class ;
rdfs:label "diterpenoid" ;
rdfs:comment "Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." ;
rdfs:subClassOf obo:CHEBI_26873 .
obo:GO_0030952 a rdfs:Class ;
rdfs:label "establishment or maintenance of cytoskeleton polarity" ;
rdfs:comment "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0007010 , obo:GO_0007163 .
obo:UBERON_0002298 a rdfs:Class ;
rdfs:label "brainstem" ;
rdfs:comment "Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_0050900 a rdfs:Class ;
rdfs:label "leukocyte migration" ;
rdfs:comment "The movement of a leukocyte within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0016477 .
obo:PATO_0000411 a rdfs:Class ;
rdfs:label "circular" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center." ;
rdfs:subClassOf obo:PATO_0000947 .
obo:UBERON_0001090 a rdfs:Class ;
rdfs:label "synovial fluid" ;
rdfs:comment "Joint fluid is a transudate of plasma that is actively secreted by synovial cells." ;
rdfs:subClassOf obo:UBERON_0007779 , obo:UBERON_0007794 .
obo:PHIPO_0000701 a rdfs:Class ;
rdfs:label "resistance to vancomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to vancomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_48356 a rdfs:Class ;
rdfs:label "protic solvent" ;
rdfs:comment "A polar solvent that is capable of acting as a hydron (proton) donor." ;
rdfs:subClassOf obo:CHEBI_39141 , obo:CHEBI_48354 .
obo:GO_0045995 a rdfs:Class ;
rdfs:label "regulation of embryonic development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of embryonic development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000026 .
obo:GO_0030852 a rdfs:Class ;
rdfs:label "regulation of granulocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of granulocyte differentiation." ;
rdfs:subClassOf obo:GO_0002761 , obo:GO_0065007 .
obo:CHEBI_36347 a rdfs:Class ;
rdfs:label "nuclear particle" ;
rdfs:comment "A nucleus or any of its constituents in any of their energy states." ;
rdfs:subClassOf obo:CHEBI_36342 .
obo:PHIPO_0000499 a rdfs:Class ;
rdfs:label "obsolete normal synthesis of deoxynivalenol" ;
rdfs:comment "A single organism phenotype in which the biosynthesis of deoxynivalenol is normal (i.e. same as the wild type)." .
obo:UBERON_0000466 a rdfs:Class ;
rdfs:label "immaterial anatomical entity" ;
rdfs:comment "Anatomical entity that has no mass." ;
rdfs:subClassOf obo:BFO_0000141 , obo:UBERON_0001062 .
obo:PHIPO_0000331 a rdfs:Class ;
rdfs:label "pathogen penetration into host present"@en ;
rdfs:comment "A pathogen entry into host phenotype in which pathogen penetration into the body, tissues, or cells of the host organism is present." ;
rdfs:subClassOf obo:PHIPO_0000949 .
obo:GO_0001775 a rdfs:Class ;
rdfs:label "cell activation" ;
rdfs:comment "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0032501 .
obo:GO_0003313 a rdfs:Class ;
rdfs:label "heart rudiment development" ;
rdfs:comment "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060429 .
obo:GO_0051032 a rdfs:Class ;
rdfs:label "nucleic acid transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." ;
rdfs:subClassOf obo:GO_0015932 , obo:GO_0022857 , obo:GO_0022884 .
obo:GO_0051964 a rdfs:Class ;
rdfs:label "negative regulation of synapse assembly" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ;
rdfs:subClassOf obo:GO_0051961 , obo:GO_0051963 , obo:GO_0065007 , obo:GO_1901889 , obo:GO_1905809 .
obo:GO_0045932 a rdfs:Class ;
rdfs:label "negative regulation of muscle contraction" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." ;
rdfs:subClassOf obo:GO_0006937 , obo:GO_0051241 , obo:GO_0065007 .
obo:PHIPO_0000212 a rdfs:Class ;
rdfs:label "decreased pathogen host protein-protein interaction"@en ;
rdfs:comment "A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs to a lesser extent than normal." ;
rdfs:subClassOf obo:PHIPO_0001106 .
obo:GO_0001555 a rdfs:Class ;
rdfs:label "oocyte growth" ;
rdfs:comment "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0040007 , obo:GO_0048588 .
obo:GO_0060044 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle cell proliferation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0055022 , obo:GO_0060043 , obo:GO_0065007 .
obo:UBERON_0001956 a rdfs:Class ;
rdfs:label "cartilage of bronchus" ;
rdfs:comment "The hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP]." ;
rdfs:subClassOf obo:UBERON_0003603 , obo:UBERON_0007844 .
obo:GO_0016462 a rdfs:Class ;
rdfs:label "pyrophosphatase activity" ;
rdfs:comment "Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups." ;
rdfs:subClassOf obo:GO_0016818 .
obo:UBERON_0010409 a rdfs:Class ;
rdfs:label "ocular surface region" ;
rdfs:comment "The integrated unit (of the eye) that consists of the conjunctiva, the corneal surface, and the ocular mucosal adnexa including the lid margins and the meibomian gland openings, the lacrimal glands and the lacrimal drainage system, all which are critical to maintain ocular surface integrity and provide protection from external antigens and pathogenic microorganisms." ;
rdfs:subClassOf obo:UBERON_0000063 .
obo:UBERON_0000064 a rdfs:Class ;
rdfs:label "organ part" ;
rdfs:comment "A multicellular structure that is a part of an organ." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:UBERON_0011299 a rdfs:Class ;
rdfs:label "white matter of telencephalon" ;
rdfs:comment "A partion of white matter that is part of a telencephalon. This can be further subdivided in some species, for example, into hemisphere white matter and the corpus callosum." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0019261 .
obo:CHEBI_35410 a rdfs:Class ;
rdfs:label "primary diamine" ;
rdfs:comment "A primary diamine is a compound derived from a hydrocarbon by replacing two hydrogen atoms by amino groups." ;
rdfs:subClassOf obo:CHEBI_23666 .
obo:PATO_0001995 a rdfs:Class ;
rdfs:label "organismal quality" ;
rdfs:comment "A quality that inheres in an entire organism or part of an organism." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:GO_0035190 a rdfs:Class ;
rdfs:label "syncytial nuclear migration" ;
rdfs:comment "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisions and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex." ;
rdfs:subClassOf obo:GO_0007097 .
obo:GO_0048246 a rdfs:Class ;
rdfs:label "macrophage chemotaxis" ;
rdfs:comment "The movement of a macrophage in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0030595 , obo:GO_1905517 .
obo:GO_0051620 a rdfs:Class ;
rdfs:label "norepinephrine uptake" ;
rdfs:comment "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0090493 .
obo:GO_2000836 a rdfs:Class ;
rdfs:label "positive regulation of androgen secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of androgen secretion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000833 , obo:GO_2000834 .
obo:CHEBI_77734 a rdfs:Class ;
rdfs:label "dexverapamil" ;
rdfs:comment "A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_77733 .
obo:UBERON_0003476 a rdfs:Class ;
rdfs:label "respiratory system venous blood vessel" ;
rdfs:comment "A vein that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:PHIPO_0000312 a rdfs:Class ;
rdfs:label "obsolete abnormal effector of pathogenicity" ;
rdfs:comment "The ability to cause disease by activating or suppressing host defenses is altered compared to the wildtype interaction." .
obo:GO_0043943 a rdfs:Class ;
rdfs:label "regulation of asexual sporulation resulting in formation of a cellular spore" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis." ;
rdfs:subClassOf obo:GO_0034305 , obo:GO_0042173 , obo:GO_0065007 .
obo:PHIPO_0000509 a rdfs:Class ;
rdfs:label "population phenotype"@en ;
rdfs:comment "A single species phenotype that is observed at the level of a population." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:CHEBI_2762 a rdfs:Class ;
rdfs:label "antimycin A" ;
rdfs:comment "A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison." ;
rdfs:subClassOf obo:CHEBI_145556 , obo:CHEBI_22702 , obo:CHEBI_24079 , obo:CHEBI_33853 .
obo:GO_0040012 a rdfs:Class ;
rdfs:label "regulation of locomotion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:UBERON_0003430 a rdfs:Class ;
rdfs:label "neck nerve" ;
rdfs:comment "A nerve that is part of a neck [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:GO_0080090 a rdfs:Class ;
rdfs:label "regulation of primary metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:CHEBI_76838 a rdfs:Class ;
rdfs:label "EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor" ;
rdfs:comment "An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*)." ;
rdfs:subClassOf obo:CHEBI_76741 .
obo:GO_0007165 a rdfs:Class ;
rdfs:label "signal transduction" ;
rdfs:comment "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0050794 .
obo:PATO_0000122 a rdfs:Class ;
rdfs:label "length" ;
rdfs:comment "A 1-D extent quality which is equal to the distance between two points." ;
rdfs:subClassOf obo:PATO_0001708 .
obo:CHEBI_77569 a rdfs:Class ;
rdfs:label "trovafloxacin(1+)" ;
rdfs:comment "An organic cation that is the conjugate acid of trovafloxacin, obtained by protonation of the primary amino group." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:CHEBI_5686 a rdfs:Class ;
rdfs:label "heterocyclic compound" ;
rdfs:comment "A cyclic compound having as ring members atoms of at least two different elements." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:UBERON_0010291 a rdfs:Class ;
rdfs:label "layer of sclera" ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:CL_0000329 a rdfs:Class ;
rdfs:label "oxygen accumulating cell" ;
rdfs:comment "Any cell that is capable of some oxygen transport." ;
rdfs:subClassOf obo:CL_0000000 .
obo:CHEBI_35444 a rdfs:Class ;
rdfs:label "antinematodal drug" ;
rdfs:comment "A substance used in the treatment or control of nematode infestations." ;
rdfs:subClassOf obo:CHEBI_25491 , obo:CHEBI_35443 .
obo:GO_1904753 a rdfs:Class ;
rdfs:label "negative regulation of vascular associated smooth muscle cell migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration." ;
rdfs:subClassOf obo:GO_0014912 , obo:GO_0065007 , obo:GO_1904752 .
obo:UBERON_0007831 a rdfs:Class ;
rdfs:label "pectoral girdle skeleton" ;
rdfs:comment "A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons." ;
rdfs:subClassOf obo:UBERON_0010719 , obo:UBERON_0010912 .
a rdf:Property ;
rdfs:label "proximally connected to" ;
rdfs:comment "x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y." ;
rdfs:range ;
rdfs:subPropertyOf obo:BSPO_0000097 , obo:RO_0002170 , .
obo:CHEBI_141153 a rdfs:Class ;
rdfs:label "quinone outside inhibitor" ;
rdfs:comment "A mitochondrial cytochrome-bc1 complex inhibitor that acts at the Quinone 'outer' (Qo) binding site of the cytochrome-bc1 complex." ;
rdfs:subClassOf obo:CHEBI_24127 , obo:CHEBI_38499 .
obo:UBERON_0000111 a rdfs:Class ;
rdfs:label "organogenesis stage" ;
rdfs:comment "A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:PHIPO_0000069 a rdfs:Class ;
rdfs:label "sexual spores decreased in size"@en ;
rdfs:comment "A reproductive morphology phenotype where the size of the sexual spore is decreased." ;
rdfs:subClassOf obo:PHIPO_0000071 .
obo:GO_0043168 a rdfs:Class ;
rdfs:label "anion binding" ;
rdfs:comment "Binding to an anion, a charged atom or group of atoms with a net negative charge." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0043167 .
obo:PR_O09100 a rdfs:Class ;
rdfs:label "endothelial transcription factor GATA-2 (mouse)" ;
rdfs:comment "An endothelial transcription factor GATA-2 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000007858 , obo:PR_000029032 .
obo:GO_0010565 a rdfs:Class ;
rdfs:label "regulation of ketone metabolic process" ;
rdfs:comment "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:CHEBI_83752 a rdfs:Class ;
rdfs:label "(2S,3R)-cyproconazole" ;
rdfs:comment "The (2S,3R)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol." ;
rdfs:subClassOf obo:CHEBI_83748 .
obo:UBERON_0007914 a rdfs:Class ;
rdfs:label "bone of craniocervical region" ;
rdfs:comment "A bone that is part of a craniocervical region." ;
rdfs:subClassOf obo:UBERON_0001474 .
obo:PHIPO_0000041 a rdfs:Class ;
rdfs:label "obsolete normal motility phenotype" ;
rdfs:comment "bacteria flagella aphid flight nematode wiggle fungi non-motile (apart from spores) also hosts" .
obo:CHEBI_58958 a rdfs:Class ;
rdfs:label "organosulfate oxoanion" ;
rdfs:comment "An organic anion of general formula RS(=O)2O(−) where R is an organyl group." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_33482 .
obo:GO_0009628 a rdfs:Class ;
rdfs:label "response to abiotic stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." ;
rdfs:subClassOf obo:GO_0050896 .
obo:CHEBI_35189 a rdfs:Class ;
rdfs:label "sesquiterpene" ;
rdfs:comment "A C15 terpene." ;
rdfs:subClassOf obo:CHEBI_35186 .
obo:GO_0008284 a rdfs:Class ;
rdfs:label "positive regulation of cell population proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0048522 , obo:GO_0065007 .
obo:GO_2000464 a rdfs:Class ;
rdfs:label "positive regulation of astrocyte chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0050921 , obo:GO_0065007 , obo:GO_1903977 , obo:GO_2000458 .
obo:GO_0043937 a rdfs:Class ;
rdfs:label "regulation of sporulation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0140101 a rdfs:Class ;
rdfs:label "catalytic activity, acting on a tRNA" ;
rdfs:comment "Catalytic activity that acts to modify a tRNA." ;
rdfs:subClassOf obo:GO_0003824 , obo:GO_0140098 .
obo:GO_0043903 a rdfs:Class ;
rdfs:label "regulation of biological process involved in symbiotic interaction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:UBERON_0003463 a rdfs:Class ;
rdfs:label "trunk bone" ;
rdfs:comment "A bone that is part of a trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0005177 .
obo:CHEBI_76863 a rdfs:Class ;
rdfs:label "EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor" ;
rdfs:comment "An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD+ or NADP+ as acceptor (EC 1.5.1.*)." ;
rdfs:subClassOf obo:CHEBI_76731 .
obo:PHIPO_0000246 a rdfs:Class ;
rdfs:label "abolished pathogen protein localization within host"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the localization of a pathogen protein to a host structure or compartment is abolished (i.e. the protein was localized to the host structure or compartment and now is not)." ;
rdfs:subClassOf obo:PHIPO_0000240 .
obo:GO_2000573 a rdfs:Class ;
rdfs:label "positive regulation of DNA biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010557 , obo:GO_0051054 , obo:GO_0065007 , obo:GO_2000278 .
obo:CL_0020007 a rdfs:Class ;
rdfs:label "dorso-striatal cholinergic-GABAergic neuron" ;
rdfs:comment "A transcriptomically defined GABAergic neuron in the dorsal striatum. In mice and primates, it is defined by the coexpression of choline acetyltransferase (ChAT) together with the GABAergic markers glutamate decarboxylase 65 (GAD65/Gad2) and vesicular GABA transporter (VGAT/Slc32a1) (Lozovaya et al., 2018)." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_0008061 , obo:CL_0011005 .
obo:GO_1903708 a rdfs:Class ;
rdfs:label "positive regulation of hemopoiesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of hemopoiesis." ;
rdfs:subClassOf obo:GO_0002684 , obo:GO_0010720 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1903706 .
obo:CHEBI_15022 a rdfs:Class ;
rdfs:label "electron donor" ;
rdfs:comment "A molecular entity that can transfer an electron to another molecular entity." ;
rdfs:subClassOf obo:CHEBI_17891 .
obo:CL_0002350 a rdfs:Class ;
rdfs:label "endocardial cell" ;
rdfs:comment "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin." ;
rdfs:subClassOf obo:CL_0000115 , obo:CL_0010008 .
obo:UBERON_0006537 a rdfs:Class ;
rdfs:label "female reproductive gland secretion" ;
rdfs:comment "A portion of organism substance that is secreted by a female reproductive gland." ;
rdfs:subClassOf obo:UBERON_0000463 , obo:UBERON_0022293 .
obo:UBERON_0005172 a rdfs:Class ;
rdfs:label "abdomen element" ;
rdfs:comment "An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0005173 .
obo:CHEBI_76567 a rdfs:Class ;
rdfs:label "polyunsaturated fatty acid anion" ;
rdfs:comment "Any unsaturated fatty acid anion containing more than one C-C unsaturated bond. Major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_2580 .
obo:CHEBI_15740 a rdfs:Class ;
rdfs:label "formate" ;
rdfs:comment "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects." ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:UBERON_0005837 a rdfs:Class ;
rdfs:label "fasciculus of spinal cord" ;
rdfs:comment "A fascicle that is part of a spinal cord." ;
rdfs:subClassOf obo:UBERON_0001019 , obo:UBERON_0011215 .
obo:PR_000001355 a rdfs:Class ;
rdfs:label "immunoglobulin gamma Fc receptor II/III/IV" ;
rdfs:comment "A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CL_0000550 a rdfs:Class ;
rdfs:label "polychromatophilic erythroblast" ;
rdfs:comment "A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers." ;
rdfs:subClassOf obo:CL_0000765 .
obo:GO_1902883 a rdfs:Class ;
rdfs:label "negative regulation of response to oxidative stress" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress." ;
rdfs:subClassOf obo:GO_0048585 , obo:GO_0065007 , obo:GO_1902882 .
obo:GO_1904649 a rdfs:Class ;
rdfs:label "regulation of fat cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of fat cell apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:UBERON_0003387 a rdfs:Class ;
rdfs:label "smooth muscle of trachea" ;
rdfs:comment "A portion of smooth muscle tissue that is part of a trachea [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004233 .
obo:GO_0021547 a rdfs:Class ;
rdfs:label "midbrain-hindbrain boundary initiation" ;
rdfs:comment "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." ;
rdfs:subClassOf obo:GO_0003002 , obo:GO_0048646 , obo:GO_0048859 .
obo:GO_0061450 a rdfs:Class ;
rdfs:label "trophoblast cell migration" ;
rdfs:comment "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst." ;
rdfs:subClassOf obo:GO_0001667 , obo:GO_0016477 .
obo:PR_000017299 a rdfs:Class ;
rdfs:label "VIP peptides" ;
rdfs:comment "A protein that is a translation product of the human VIP gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PHIPO_0000443 a rdfs:Class ;
rdfs:label "normal pathogen sexual reproduction within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host where the pathogen sexual reproduction process, in which new individuals are produced by combining the genetic material of two gametes, which may come from two organisms or from a single organism is normal (indistinguishable from wild type) (GO:0019953)." ;
rdfs:subClassOf obo:PHIPO_0000440 .
obo:PHIPO_0001185 a rdfs:Class ;
rdfs:label "obsolete gain of functional host resistance gene" ;
rdfs:comment "A phenotype where the ability of a host, to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene is acquired (resistance was absent and is now present)." .
obo:CHEBI_137419 a rdfs:Class ;
rdfs:label "secondary ammonium ion" ;
rdfs:comment "An organic cation obtained by protonation of any secondary amino compound; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_0042065 a rdfs:Class ;
rdfs:label "glial cell growth" ;
rdfs:comment "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." ;
rdfs:subClassOf obo:GO_0040007 , obo:GO_0048588 .
obo:GO_0019787 a rdfs:Class ;
rdfs:label "ubiquitin-like protein transferase activity" ;
rdfs:comment "Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein." ;
rdfs:subClassOf obo:GO_0016755 , obo:GO_0140096 .
obo:GO_2000673 a rdfs:Class ;
rdfs:label "positive regulation of motor neuron apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process." ;
rdfs:subClassOf obo:GO_0043525 , obo:GO_0065007 , obo:GO_2000671 .
obo:PHIPO_0000016 a rdfs:Class ;
rdfs:label "normal single species phenotype" ;
rdfs:comment "A single organism phenotype which is normal (i.e. the same as wild-type)." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:GO_1900119 a rdfs:Class ;
rdfs:label "positive regulation of execution phase of apoptosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0065007 , obo:GO_1900117 .
obo:GO_0045661 a rdfs:Class ;
rdfs:label "regulation of myoblast differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:GO_0060019 a rdfs:Class ;
rdfs:label "radial glial cell differentiation" ;
rdfs:comment "The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0010001 , obo:GO_0030154 .
obo:CHEBI_35362 a rdfs:Class ;
rdfs:label "hydrazide" ;
rdfs:comment "Compounds derived from oxoacids RkE(=O)l(OH)m (l ≠ 0) by replacing ‒OH by ‒NRNR2 (R groups are commonly H). (IUPAC)." ;
rdfs:subClassOf obo:CHEBI_51143 .
obo:GO_0006520 a rdfs:Class ;
rdfs:label "amino acid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0044238 .
obo:PR_P32848 a rdfs:Class ;
rdfs:label "parvalbumin alpha (mouse)" ;
rdfs:comment "A parvalbumin alpha that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000013502 , obo:PR_000029032 .
obo:GO_0005215 a rdfs:Class ;
rdfs:label "transporter activity" ;
rdfs:comment "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells." ;
rdfs:subClassOf obo:GO_0003674 .
obo:GO_0002183 a rdfs:Class ;
rdfs:label "cytoplasmic translational initiation" ;
rdfs:comment "The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." ;
rdfs:subClassOf obo:GO_0006413 .
obo:GO_0007566 a rdfs:Class ;
rdfs:label "embryo implantation" ;
rdfs:comment "Attachment of the blastocyst to the uterine lining." ;
rdfs:subClassOf obo:GO_0022414 .
obo:PHIPO_0000201 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host protein complex binding" ;
rdfs:comment "A pathogen (molecular function??) phenotype in which the binding of one protein to a protein complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the protein complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene." .
obo:NCBITaxon_197562 a rdfs:Class ;
rdfs:label "Pancrustacea" ;
rdfs:subClassOf obo:NCBITaxon_197563 .
obo:GO_1905938 a rdfs:Class ;
rdfs:label "positive regulation of germ cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of germ cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1905936 .
obo:NCBITaxon_7742 a rdfs:Class ;
rdfs:label "Vertebrata " ;
rdfs:subClassOf obo:NCBITaxon_89593 .
obo:CHEBI_24062 a rdfs:Class ;
rdfs:label "fluorine molecular entity" ;
rdfs:subClassOf obo:CHEBI_24471 .
obo:GO_0150111 a rdfs:Class ;
rdfs:label "regulation of transepithelial transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of transepithelial transport." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:UBERON_0006312 a rdfs:Class ;
rdfs:label "ocular refractive media" ;
rdfs:comment "Body substance in a liquid or semi-solid state in the eyeball which serves to refract light." ;
rdfs:subClassOf obo:UBERON_0000463 .
obo:PHIPO_0000563 a rdfs:Class ;
rdfs:label "resistance to furazolidone"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to furazolidone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0000915 a rdfs:Class ;
rdfs:label "thoracic segment of trunk" ;
rdfs:comment "Subdivision of trunk that lies between the head and the abdomen." ;
rdfs:subClassOf obo:UBERON_0009569 , obo:UBERON_0011676 .
obo:UBERON_0003613 a rdfs:Class ;
rdfs:label "cardiovascular system elastic tissue" ;
rdfs:comment "An elastic tissue that is part of a circulatory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002521 .
obo:GO_0120006 a rdfs:Class ;
rdfs:label "regulation of glutamatergic neuron differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation." ;
rdfs:subClassOf obo:GO_0045664 , obo:GO_0065007 .
obo:GO_0051338 a rdfs:Class ;
rdfs:label "regulation of transferase activity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." ;
rdfs:subClassOf obo:GO_0050790 , obo:GO_0065007 .
obo:UBERON_0009030 a rdfs:Class ;
rdfs:label "left pulmonary vein" ;
rdfs:comment "Vein that drains left lung and returns blood to the heart." ;
rdfs:subClassOf obo:UBERON_0002016 .
obo:GO_1905457 a rdfs:Class ;
rdfs:label "negative regulation of lymphoid progenitor cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901533 , obo:GO_1905456 .
obo:UBERON_0002532 a rdfs:Class ;
rdfs:label "epiblast (generic)" ;
rdfs:comment "In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA]." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0051707 a rdfs:Class ;
rdfs:label "response to other organism" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." ;
rdfs:subClassOf obo:GO_0043207 , obo:GO_0044419 .
obo:CHEBI_72316 a rdfs:Class ;
rdfs:label "virulence factor" ;
rdfs:comment "Any toxin secreted by bacteria, viruses, fungi or protozoa enabling them to achieve colonisation of a niche in the host, inhibit or evade the host's immune response, enter and exit cells, or obtain nutrition from the host." ;
rdfs:subClassOf obo:CHEBI_27026 .
obo:PHIPO_0000365 a rdfs:Class ;
rdfs:label "decreased pathogen growth within host"@en ;
rdfs:comment "A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host is decreased." ;
rdfs:subClassOf obo:PHIPO_0000954 .
obo:PHIPO_0001229 a rdfs:Class ;
rdfs:label "presence of pathogen tissue to tissue migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally from tissue to tissue within the host organism is present." ;
rdfs:subClassOf obo:PHIPO_0001159 .
obo:CL_2000016 a rdfs:Class ;
rdfs:label "lung microvascular endothelial cell" ;
rdfs:comment "Any lung endothelial cell that is part of a microvascular endothelium." ;
rdfs:subClassOf obo:CL_1001567 , obo:CL_2000008 .
obo:GO_1901956 a rdfs:Class ;
rdfs:label "positive regulation of retrograde dense core granule transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901610 , obo:GO_1901954 , obo:GO_1904811 , obo:GO_2001019 .
a rdfs:Class ;
rdfs:label "NPY" ;
rdfs:subClassOf obo:SO_0000704 .
obo:UBERON_0011779 a rdfs:Class ;
rdfs:label "nerve of head region" ;
rdfs:comment "A nerve that is part of a head." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:GO_2000690 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle cell myoblast differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation." ;
rdfs:subClassOf obo:GO_0045661 , obo:GO_0051890 , obo:GO_0065007 .
obo:CL_4042025 a rdfs:Class ;
rdfs:label "substantia nigra dopaminergic neuron"@en ;
rdfs:comment "A midbrain dopaminergic neuron that has its soma located in a substantia nigra. This dopaminergic neuron type is highly metabolically active and it is involved in the regulation of movement, cognition, motivation and reward. Neurodegeneration of this dopaminergic neuronal type causes loss in fine motor control in Parkinson's Disease." ;
rdfs:subClassOf obo:CL_0002614 , obo:CL_2000097 .
obo:GO_0043542 a rdfs:Class ;
rdfs:label "endothelial cell migration" ;
rdfs:comment "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." ;
rdfs:subClassOf obo:GO_0016477 .
obo:GO_0070459 a rdfs:Class ;
rdfs:label "prolactin secretion" ;
rdfs:comment "The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary." ;
rdfs:subClassOf obo:GO_0009306 , obo:GO_0030072 , obo:GO_0046903 .
obo:GO_0021822 a rdfs:Class ;
rdfs:label "negative regulation of cell motility involved in cerebral cortex radial glia guided migration" ;
rdfs:comment "The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903976 .
obo:UBERON_0013702 a rdfs:Class ;
rdfs:label "body proper" ;
rdfs:comment "The region of the organism associated with the visceral organs." ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:CHEBI_33555 a rdfs:Class ;
rdfs:label "arenesulfonic acid" ;
rdfs:comment "Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an aryl group." ;
rdfs:subClassOf obo:CHEBI_33551 .
obo:PHIPO_0001269 a rdfs:Class ;
rdfs:label "decreased number of host galls during pathogen invasion"@en ;
rdfs:comment "A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in a decreased number of plant galls (BTO:0005833 plant gall)." ;
rdfs:subClassOf obo:PHIPO_0001268 .
obo:CHEBI_7934 a rdfs:Class ;
rdfs:label "paromomycin" ;
rdfs:comment "An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-α-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis." ;
rdfs:subClassOf obo:CHEBI_22479 , obo:CHEBI_22507 , obo:CHEBI_61800 .
obo:GO_0032414 a rdfs:Class ;
rdfs:label "positive regulation of ion transmembrane transporter activity" ;
rdfs:comment "Any process that activates or increases the activity of an ion transporter." ;
rdfs:subClassOf obo:GO_0022898 , obo:GO_0032411 , obo:GO_0034767 , obo:GO_0065007 .
obo:CHEBI_23117 a rdfs:Class ;
rdfs:label "chlorine molecular entity" ;
rdfs:comment "A halogen molecular entity containing one or more atoms of chlorine." ;
rdfs:subClassOf obo:CHEBI_24471 .
obo:UBERON_0005234 a rdfs:Class ;
rdfs:label "optic eminence ectoderm" ;
rdfs:comment "An ectoderm that is part of a optic eminence [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000924 .
obo:CHEBI_76916 a rdfs:Class ;
rdfs:label "hyperglycemic agent" ;
rdfs:comment "A drug which increases the blood glucose level." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0010817 a rdfs:Class ;
rdfs:label "regulation of hormone levels" ;
rdfs:comment "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." ;
rdfs:subClassOf obo:GO_0065008 .
obo:CHEBI_24797 a rdfs:Class ;
rdfs:label "indole phytoalexin" ;
rdfs:subClassOf obo:CHEBI_24828 .
obo:GO_0070229 a rdfs:Class ;
rdfs:label "negative regulation of lymphocyte apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070228 , obo:GO_2000107 .
obo:UBERON_0019262 a rdfs:Class ;
rdfs:label "white matter of myelencephalon" ;
rdfs:comment "A white matter that is part of the myelencephalon." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0019258 .
obo:CHEBI_91007 a rdfs:Class ;
rdfs:label "aromatic carboxylate" ;
rdfs:comment "A carboxylic acic anion obtained by deprotonation of the carboxy group of any aromatic carboxylic acid. Major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:PHIPO_0000424 a rdfs:Class ;
rdfs:label "increased carbohydrate binding"@en ;
rdfs:comment "A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000419 .
obo:PHIPO_0000580 a rdfs:Class ;
rdfs:label "resistance to sulfadimethoxine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to sulfadimethoxine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_33242 a rdfs:Class ;
rdfs:label "inorganic hydride" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_33692 .
obo:GO_0046890 a rdfs:Class ;
rdfs:label "regulation of lipid biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0019216 , obo:GO_0065007 .
obo:GO_0048641 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle tissue development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development." ;
rdfs:subClassOf obo:GO_0016202 , obo:GO_0065007 .
obo:GO_0006886 a rdfs:Class ;
rdfs:label "intracellular protein transport" ;
rdfs:comment "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015031 , obo:GO_0046907 .
obo:GO_0110111 a rdfs:Class ;
rdfs:label "negative regulation of animal organ morphogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_2000027 .
obo:PR_000013502 a rdfs:Class ;
rdfs:label "parvalbumin alpha" ;
rdfs:comment "A protein that is a translation product of the human PVALB gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PHIPO_0001457 a rdfs:Class ;
rdfs:label "increased susceptibility to pathogen"@en ;
rdfs:comment "A quality of an organism describing an increased proneness to infection, colonization, or disease development following exposure to a pathogen relative to a reference organism or population under equivalent conditions." ;
rdfs:subClassOf obo:PHIPO_0001456 .
obo:UBERON_0000378 a rdfs:Class ;
rdfs:label "tongue muscle" ;
rdfs:comment "The muscular portion of the tongue." ;
rdfs:subClassOf obo:UBERON_0013765 , obo:UBERON_0014892 .
obo:UBERON_0001268 a rdfs:Class ;
rdfs:label "peritoneal fluid" ;
rdfs:comment "Transudate contained in the peritoneal cavity." ;
rdfs:subClassOf obo:UBERON_0007779 , obo:UBERON_0007794 , obo:UBERON_0036217 .
obo:PHIPO_0000419 a rdfs:Class ;
rdfs:label "abnormal carbohydrate binding"@en ;
rdfs:comment "A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000413 , obo:PHIPO_0000430 .
obo:CL_0002494 a rdfs:Class ;
rdfs:label "cardiocyte" ;
rdfs:comment "A cell located in the heart, including both muscle and non muscle cells." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_0045920 a rdfs:Class ;
rdfs:label "negative regulation of exocytosis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." ;
rdfs:subClassOf obo:GO_0017157 , obo:GO_0065007 , obo:GO_1903531 .
obo:GO_2001235 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic signaling pathway" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway." ;
rdfs:subClassOf obo:GO_0009967 , obo:GO_0043065 , obo:GO_0065007 , obo:GO_2001233 .
obo:UBERON_0005726 a rdfs:Class ;
rdfs:label "chemosensory system" ;
rdfs:subClassOf obo:UBERON_0001032 .
obo:CHEBI_23677 a rdfs:Class ;
rdfs:label "diazole" ;
rdfs:comment "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." ;
rdfs:subClassOf obo:CHEBI_68452 .
obo:PHIPO_0001449 a rdfs:Class ;
rdfs:label "sensitive to ammonium"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ammonium. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0031110 a rdfs:Class ;
rdfs:label "regulation of microtubule polymerization or depolymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070507 .
obo:CHEBI_45979 a rdfs:Class ;
rdfs:label "thiabendazole" ;
rdfs:comment "A member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including Aspergillus, Botrytis, Cladosporium and Fusarium." ;
rdfs:subClassOf obo:CHEBI_38418 , obo:CHEBI_87036 .
obo:UBERON_0007601 a rdfs:Class ;
rdfs:label "ciliated epithelium" ;
rdfs:comment "Epithelium bearing vibratile cilia on the free surface." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0048391 a rdfs:Class ;
rdfs:label "intermediate mesoderm formation" ;
rdfs:comment "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0001707 , obo:GO_0048646 .
obo:GO_0046549 a rdfs:Class ;
rdfs:label "retinal cone cell development" ;
rdfs:comment "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0042462 .
obo:GO_0042645 a rdfs:Class ;
rdfs:label "mitochondrial nucleoid" ;
rdfs:comment "The region of a mitochondrion to which the DNA is confined." ;
rdfs:subClassOf obo:GO_0009295 , obo:GO_0043232 .
obo:GO_0061890 a rdfs:Class ;
rdfs:label "positive regulation of astrocyte activation" ;
rdfs:comment "Any process that increases the frequency, rate or extent of astrocyte activation." ;
rdfs:subClassOf obo:GO_0048711 , obo:GO_0050867 , obo:GO_0061888 , obo:GO_0065007 , obo:GO_0150078 .
obo:PHIPO_0000301 a rdfs:Class ;
rdfs:label "normal dissemination of asexual spore"@en ;
rdfs:comment "A single species phenotype where the dispersal of asexual spores is normal (FAO:0000023)." ;
rdfs:subClassOf obo:PHIPO_0000044 .
obo:CHEBI_76668 a rdfs:Class ;
rdfs:label "EC 2.7.* (P-containing group transferase) inhibitor" ;
rdfs:comment "A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*)." ;
rdfs:subClassOf obo:CHEBI_71300 .
obo:GO_0032239 a rdfs:Class ;
rdfs:label "regulation of nucleobase-containing compound transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:CL_0002570 a rdfs:Class ;
rdfs:label "mesenchymal stem cell of adipose tissue" ;
rdfs:comment "A mesenchymal stem cell of adipose tissue." ;
rdfs:subClassOf obo:CL_0000134 .
obo:GO_0045760 a rdfs:Class ;
rdfs:label "positive regulation of action potential" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0065007 , obo:GO_0098900 .
obo:CHEBI_35620 a rdfs:Class ;
rdfs:label "vasodilator agent" ;
rdfs:comment "A drug used to cause dilation of the blood vessels." ;
rdfs:subClassOf obo:CHEBI_35554 .
obo:CL_0000050 a rdfs:Class ;
rdfs:label "megakaryocyte-erythroid progenitor cell" ;
rdfs:comment "A progenitor cell committed to the megakaryocyte and erythroid lineages." ;
rdfs:subClassOf obo:CL_0000763 , obo:CL_0002032 , obo:CL_0011026 .
obo:CL_0000763 a rdfs:Class ;
rdfs:label "myeloid cell" ;
rdfs:comment "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000988 .
obo:CL_4300366 a rdfs:Class ;
rdfs:label "oligodendrocyte precursor cell (Mmus)" ;
rdfs:comment "A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:326 OPC NN." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0002453 , obo:CL_4300031 .
obo:GO_0098798 a rdfs:Class ;
rdfs:label "mitochondrial protein-containing complex" ;
rdfs:comment "A protein complex that is part of a mitochondrion." ;
rdfs:subClassOf obo:GO_0032991 .
obo:CHEBI_35014 a rdfs:Class ;
rdfs:label "thiophanate-methyl" ;
rdfs:comment "A member of the class of thioureas that is the dimethyl ester of (1,2-phenylenedicarbamothioyl)biscarbamic acid. A fungicide effective against a broad spectrum of diseases in fruit, vegetables, turf and other crops including eyespot, scab, powdery mildew and grey mould." ;
rdfs:subClassOf obo:CHEBI_51276 , obo:CHEBI_87037 , obo:CHEBI_87061 .
obo:GO_0003292 a rdfs:Class ;
rdfs:label "cardiac septum cell differentiation" ;
rdfs:comment "The process in which an endocardial cushion cell becomes a cell of a cardiac septum." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0035051 .
obo:SO_0001260 a rdfs:Class ;
rdfs:label "sequence_collection" .
obo:CHEBI_35286 a rdfs:Class ;
rdfs:label "iminium ion" ;
rdfs:comment "Cations of structure R2C=N+R2." ;
rdfs:subClassOf obo:CHEBI_25697 .
obo:GO_0002688 a rdfs:Class ;
rdfs:label "regulation of leukocyte chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0002685 , obo:GO_0050920 , obo:GO_0065007 .
obo:CHEBI_26959 a rdfs:Class ;
rdfs:label "thiocarboxylic ester" ;
rdfs:comment "An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur." ;
rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_35701 .
obo:GO_0030163 a rdfs:Class ;
rdfs:label "protein catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0009057 , obo:GO_0019538 .
obo:CHEBI_87061 a rdfs:Class ;
rdfs:label "carbamate fungicide" ;
rdfs:comment "Compounds that contain a carbamate ester moiety as a key feature of their structure and which have been used as fungicides." ;
rdfs:subClassOf obo:CHEBI_23003 .
obo:GO_0046651 a rdfs:Class ;
rdfs:label "lymphocyte proliferation" ;
rdfs:comment "The expansion of a lymphocyte population by cell division." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0032943 , obo:GO_0046649 .
obo:PHIPO_0000689 a rdfs:Class ;
rdfs:label "resistance to chloramphenicol"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to chloramphenicol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0004491 a rdfs:Class ;
rdfs:label "cardiac muscle tissue of interatrial septum" ;
rdfs:comment "A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001133 , obo:UBERON_0004492 .
obo:GO_0099601 a rdfs:Class ;
rdfs:label "regulation of neurotransmitter receptor activity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors." ;
rdfs:subClassOf obo:GO_0010469 , obo:GO_0065007 .
obo:UBERON_0004802 a rdfs:Class ;
rdfs:label "respiratory tract epithelium" ;
rdfs:comment "The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004807 , obo:UBERON_0010499 .
obo:GO_0061512 a rdfs:Class ;
rdfs:label "protein localization to cilium" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a cilium." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033365 .
obo:PHIPO_0000874 a rdfs:Class ;
rdfs:label "sensitive to tobramycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tobramycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0034242 a rdfs:Class ;
rdfs:label "negative regulation of syncytium formation by plasma membrane fusion" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0060142 , obo:GO_0065007 .
obo:GO_0021620 a rdfs:Class ;
rdfs:label "hypoglossal nerve formation" ;
rdfs:comment "The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." ;
rdfs:subClassOf obo:GO_0021603 , obo:GO_0048646 .
obo:GO_0003212 a rdfs:Class ;
rdfs:label "cardiac left atrium morphogenesis" ;
rdfs:comment "The process in which the left cardiac atrium is generated and organized." ;
rdfs:subClassOf obo:GO_0003209 , obo:GO_0009653 .
obo:GO_0090162 a rdfs:Class ;
rdfs:label "establishment of epithelial cell polarity" ;
rdfs:comment "The specification and formation of anisotropic intracellular organization of an epithelial cell." ;
rdfs:subClassOf obo:GO_0030010 .
obo:GO_0050679 a rdfs:Class ;
rdfs:label "positive regulation of epithelial cell proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of epithelial cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0050678 , obo:GO_0065007 .
obo:CHEBI_36624 a rdfs:Class ;
rdfs:label "naphthyridine" ;
rdfs:comment "Any one of eight organic heterobicyclic compounds that have a naphthalene skeleton in which two of the carbons are replaced by nitrogens. A 'closed' class." ;
rdfs:subClassOf obo:CHEBI_35570 , obo:CHEBI_50893 , obo:CHEBI_52362 .
obo:UBERON_0003556 a rdfs:Class ;
rdfs:label "forebrain arachnoid mater" ;
rdfs:comment "An arachnoid mater that is part of a forebrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002362 , obo:UBERON_0003548 .
obo:CHEBI_50919 a rdfs:Class ;
rdfs:label "antiemetic" ;
rdfs:comment "A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:PHIPO_0001226 a rdfs:Class ;
rdfs:label "decreased level of host defense-induced reducing sugar in apoplast"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host produced reducing sugars usually present in the apoplast during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:UBERON_0007500 a rdfs:Class ;
rdfs:label "epithelial tube open at both ends" ;
rdfs:comment "An epithelial tube open at both ends that allows fluid flow." ;
rdfs:subClassOf obo:UBERON_0003914 .
obo:GO_0010720 a rdfs:Class ;
rdfs:label "positive regulation of cell development" ;
rdfs:comment "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0060284 , obo:GO_0065007 .
obo:CHEBI_27902 a rdfs:Class ;
rdfs:label "tetracycline" ;
rdfs:comment "A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria." ;
rdfs:subClassOf obo:CHEBI_139592 , obo:CHEBI_26895 .
obo:PHIPO_0001001 a rdfs:Class ;
rdfs:label "abnormal organization of pathogen septin collar during cell to cell migration"@en ;
rdfs:comment "A pathogen host interaction phenotype where the morphology of the pathogen septin collar (GO:0032173) during host colonization is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0000334 , obo:PHIPO_0000999 .
obo:GO_0006027 a rdfs:Class ;
rdfs:label "glycosaminoglycan catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units." ;
rdfs:subClassOf obo:GO_0006026 , obo:GO_0009056 , obo:GO_0030203 .
obo:CHEBI_26271 a rdfs:Class ;
rdfs:label "proline" ;
rdfs:comment "An α-amino acid that is pyrrolidine bearing a carboxy substituent at position 2." ;
rdfs:subClassOf obo:CHEBI_33704 , obo:CHEBI_38260 .
obo:CHEBI_50533 a rdfs:Class ;
rdfs:label "protein denaturant" ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:CL_4300351 a rdfs:Class ;
rdfs:label "CBX MLI Megf11 Gaba molecular layer interneuron (Mmus)" ;
rdfs:comment "A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Homer3 (Mmus), Tfap2b (Mmus), Sorcs3 (Mmus), Cacna1e (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:311 CBX MLI Megf11 Gaba." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4042035 , obo:CL_4300028 .
obo:PATO_0000460 a rdfs:Class ;
rdfs:label "abnormal" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's deviation from normal or average." ;
rdfs:subClassOf obo:PATO_0000069 .
obo:GO_0061117 a rdfs:Class ;
rdfs:label "negative regulation of heart growth" ;
rdfs:comment "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." ;
rdfs:subClassOf obo:GO_0046621 , obo:GO_0060420 , obo:GO_0065007 .
obo:UBERON_0003850 a rdfs:Class ;
rdfs:label "telencephalon neural crest" ;
rdfs:comment "A neural crest that has_potential_to_developmentally_contribute_to a telencephalon." ;
rdfs:subClassOf obo:UBERON_0002342 .
obo:GO_0003352 a rdfs:Class ;
rdfs:label "regulation of cilium movement" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." ;
rdfs:subClassOf obo:GO_0060632 , obo:GO_0065007 .
obo:PHIPO_0001017 a rdfs:Class ;
rdfs:label "long germ tube"@en ;
rdfs:comment "A single species phenotype where the slender tubular outgrowth first produced by most spores in germination is longer than normal. (GO:0032179)" ;
rdfs:subClassOf obo:PHIPO_0000940 .
obo:CHEBI_25471 a rdfs:Class ;
rdfs:label "naphthalenemonosulfonate" ;
rdfs:subClassOf obo:CHEBI_25478 .
obo:GO_1901363 a rdfs:Class ;
rdfs:label "heterocyclic compound binding" ;
rdfs:comment "Binding to heterocyclic compound." ;
rdfs:subClassOf obo:GO_0036094 .
obo:GO_0098939 a rdfs:Class ;
rdfs:label "dendritic transport of mitochondrion" ;
rdfs:comment "The directed movement of mitochondria along microtubules in nerve cell dendrites." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0047497 , obo:GO_0098935 .
obo:GO_0140237 a rdfs:Class ;
rdfs:label "translation at presynapse, modulating chemical synaptic transmission" ;
rdfs:comment "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission." ;
rdfs:subClassOf obo:GO_0006412 , obo:GO_0140236 .
obo:GO_0007008 a rdfs:Class ;
rdfs:label "outer mitochondrial membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane." ;
rdfs:subClassOf obo:GO_0007006 , obo:GO_0016043 .
obo:PHIPO_0001411 a rdfs:Class ;
rdfs:label "resistance to dalfopristin" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to dalfopristin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0002224 a rdfs:Class ;
rdfs:label "thoracic cavity" ;
rdfs:comment "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0007186 a rdfs:Class ;
rdfs:label "G protein-coupled receptor signaling pathway" ;
rdfs:comment "The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane." ;
rdfs:subClassOf obo:GO_0007165 .
obo:PHIPO_0000819 a rdfs:Class ;
rdfs:label "sensitive to carbapenems"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to carbapenems. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0010258 a rdfs:Class ;
rdfs:label "mesenchyme from rhombencephalic neural crest" ;
rdfs:comment "Mesenchyme that develops_from a rhombencephalon neural crest." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0007213 , obo:UBERON_0014387 .
obo:CHEBI_28938 a rdfs:Class ;
rdfs:label "ammonium" ;
rdfs:comment "An onium cation obtained by protonation of ammonia." ;
rdfs:subClassOf obo:CHEBI_35106 , obo:CHEBI_50313 , obo:CHEBI_60242 .
obo:CL_0001031 a rdfs:Class ;
rdfs:label "cerebellar granule cell" ;
rdfs:comment "An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers." ;
rdfs:subClassOf obo:CL_0000120 , obo:CL_2000028 , obo:UBERON_0004121 .
obo:CHEBI_33432 a rdfs:Class ;
rdfs:label "monoatomic chlorine" ;
rdfs:subClassOf obo:CHEBI_33431 , obo:CHEBI_33433 .
obo:CHEBI_23414 a rdfs:Class ;
rdfs:label "copper(II) sulfate" ;
rdfs:comment "A metal sulfate compound having copper(2+) as the metal ion." ;
rdfs:subClassOf obo:CHEBI_51336 .
obo:CHEBI_23872 a rdfs:Class ;
rdfs:label "dodecyl sulfate" ;
rdfs:subClassOf obo:CHEBI_58958 .
obo:GO_1905194 a rdfs:Class ;
rdfs:label "positive regulation of chloroplast fission" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chloroplast fission." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0065007 , obo:GO_1905192 .
obo:UBERON_0015128 a rdfs:Class ;
rdfs:label "subepicardial layer of epicardium" ;
rdfs:subClassOf obo:UBERON_0007188 .
obo:UBERON_0034769 a rdfs:Class ;
rdfs:label "lymphomyeloid tissue" ;
rdfs:subClassOf obo:UBERON_0015757 .
obo:PATO_0001748 a rdfs:Class ;
rdfs:label "invaginated" ;
rdfs:comment "A shape quality in which a portion of the outermost boundary of an entity folds in space such that a portion that was originally convex is now concave." ;
rdfs:subClassOf obo:PATO_0001857 .
obo:GO_0021501 a rdfs:Class ;
rdfs:label "prechordal plate formation" ;
rdfs:comment "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CL_4301608 a rdfs:Class ;
rdfs:label "choroid plexus epithelial cell (Mmus)" ;
rdfs:comment "A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1178 CHOR NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000706 .
obo:PR_Q8CG65 a rdfs:Class ;
rdfs:label "SCO-spondin (mouse)" ;
rdfs:comment "A SCO-spondin that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000015658 , obo:PR_000029032 .
obo:CHEBI_25900 a rdfs:Class ;
rdfs:label "aldopentose phosphate" ;
rdfs:subClassOf obo:CHEBI_35131 , obo:CHEBI_84055 .
obo:PHIPO_0000345 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction molecular function" .
obo:UBERON_0006569 a rdfs:Class ;
rdfs:label "diencephalic nucleus" ;
rdfs:comment "A nucleus of brain that is part of a diencephalon." ;
rdfs:subClassOf obo:UBERON_0002308 .
obo:CHEBI_51337 a rdfs:Class ;
rdfs:label "organic sulfate salt" ;
rdfs:subClassOf obo:CHEBI_24868 , obo:CHEBI_35175 .
obo:GO_0032077 a rdfs:Class ;
rdfs:label "positive regulation of deoxyribonuclease activity" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." ;
rdfs:subClassOf obo:GO_0043085 , obo:GO_0051054 , obo:GO_0065007 .
obo:PHIPO_0001438 a rdfs:Class ;
rdfs:label "normal growth on bifonazole" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to bifonazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0006869 a rdfs:Class ;
rdfs:label "lipid transport" ;
rdfs:comment "The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." ;
rdfs:subClassOf obo:GO_0006810 .
obo:UBERON_0009751 a rdfs:Class ;
rdfs:label "cardiac mesenchyme" ;
rdfs:comment "The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures." ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:PHIPO_0000241 a rdfs:Class ;
rdfs:label "abnormal protein complex localization"@en ;
rdfs:comment "A single organism phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000239 .
obo:GO_0007127 a rdfs:Class ;
rdfs:label "meiosis I" ;
rdfs:comment "The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei." ;
rdfs:subClassOf obo:GO_0061982 , obo:GO_0140013 .
obo:RO_0002093 a rdf:Property ;
rdfs:label "ends during" ;
rdfs:range .
obo:UBERON_0003838 a rdfs:Class ;
rdfs:label "abdominal segment connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003586 .
obo:GO_0140139 a rdfs:Class ;
rdfs:label "solid phase of basement membrane" ;
rdfs:comment "The solid compartment of the basement membrane ECM, including a specific subset of basement membrane collagens and basement membrane glycoproteins like laminins or nidogens." ;
rdfs:subClassOf obo:GO_0030312 .
obo:CHEBI_26420 a rdfs:Class ;
rdfs:label "pyridinemonocarboxylic acid" ;
rdfs:comment "A monocarboxylic acid in which the carboxy group is attached to a pyridine (or substituted pyridine) ring." ;
rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_26421 , obo:CHEBI_33859 .
obo:CHEBI_50904 a rdfs:Class ;
rdfs:label "allergen" ;
rdfs:comment "A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:UBERON_0000477 a rdfs:Class ;
rdfs:label "anatomical cluster" ;
rdfs:comment "Anatomical group whose component anatomical structures lie in close proximity to each other." ;
rdfs:subClassOf obo:UBERON_0034923 .
obo:GO_0051704 a rdfs:Class ;
rdfs:label "multi-organism process" ;
rdfs:comment "A biological process which involves another organism of the same or different species." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CL_0001021 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-positive common lymphoid progenitor" ;
rdfs:comment "A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive." ;
rdfs:subClassOf obo:CL_0000051 , obo:CL_0000995 .
obo:GO_0051378 a rdfs:Class ;
rdfs:label "serotonin binding" ;
rdfs:comment "Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0043169 , obo:GO_0043176 , obo:GO_1901363 .
obo:GO_0031643 a rdfs:Class ;
rdfs:label "positive regulation of myelination" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons." ;
rdfs:subClassOf obo:GO_0031641 , obo:GO_0031646 , obo:GO_0048522 , obo:GO_0065007 .
obo:GO_0035935 a rdfs:Class ;
rdfs:label "androgen secretion" ;
rdfs:comment "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates." ;
rdfs:subClassOf obo:GO_0035929 .
obo:GO_0048852 a rdfs:Class ;
rdfs:label "diencephalon morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_36915 a rdfs:Class ;
rdfs:label "inorganic cation" ;
rdfs:subClassOf obo:CHEBI_36914 , obo:CHEBI_36916 .
obo:PR_000001022 a rdfs:Class ;
rdfs:label "neural cell adhesion molecule" ;
rdfs:comment "A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_78675 a rdfs:Class ;
rdfs:label "fundamental metabolite" ;
rdfs:comment "Any metabolite produced by all living cells." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:UBERON_0005456 a rdfs:Class ;
rdfs:label "jugular foramen" ;
rdfs:comment "The jugular foramen is a large aperture in the base of the skull. It is located behind the carotid canal and is formed in front by the petrous portion of the temporal, and behind by the occipital; it is generally larger on the right than on the left side." ;
rdfs:subClassOf obo:UBERON_0013685 , obo:UBERON_0018321 .
obo:GO_0061155 a rdfs:Class ;
rdfs:label "pulmonary artery endothelial tube morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0061154 .
obo:CHEBI_66981 a rdfs:Class ;
rdfs:label "ophthalmology drug" ;
rdfs:comment "Any compound used for the treatment of eye conditions or eye diseases." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0001990 a rdfs:Class ;
rdfs:label "regulation of systemic arterial blood pressure by hormone" ;
rdfs:comment "The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action." ;
rdfs:subClassOf obo:GO_0003044 , obo:GO_0050886 .
obo:UBERON_0000075 a rdfs:Class ;
rdfs:label "subdivision of skeletal system" ;
rdfs:comment "Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:GO_0032369 a rdfs:Class ;
rdfs:label "negative regulation of lipid transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032368 , obo:GO_0051051 , obo:GO_0065007 , obo:GO_1905953 .
obo:UBERON_0006338 a rdfs:Class ;
rdfs:label "lateral ventricle choroid plexus stroma" ;
rdfs:comment "A choroid plexus stroma that is part of a lateral ventricle." ;
rdfs:subClassOf obo:UBERON_0005206 .
obo:GO_0019896 a rdfs:Class ;
rdfs:label "axonal transport of mitochondrion" ;
rdfs:comment "The directed movement of mitochondria along microtubules in nerve cell axons." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0047497 , obo:GO_0098930 .
obo:CHEBI_27565 a rdfs:Class ;
rdfs:label "4-aminosalicylic acid" ;
rdfs:comment "An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4." ;
rdfs:subClassOf obo:CHEBI_22495 , obo:CHEBI_33853 .
obo:CHEBI_83689 a rdfs:Class ;
rdfs:label "(S)-fenarimol" ;
rdfs:comment "A (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol that has S configuration." ;
rdfs:subClassOf obo:CHEBI_83686 .
obo:GO_0021854 a rdfs:Class ;
rdfs:label "hypothalamus development" ;
rdfs:comment "The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_77738 a rdfs:Class ;
rdfs:label "(S)-verapamil(1+)" ;
rdfs:comment "An ammonium ion resulting from the protonation of the tertiary amino group of (S)-verapamil." ;
rdfs:subClassOf obo:CHEBI_35274 .
obo:GO_1900407 a rdfs:Class ;
rdfs:label "regulation of cellular response to oxidative stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cellular response to oxidative stress." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080135 , obo:GO_1902882 .
obo:GO_0098728 a rdfs:Class ;
rdfs:label "germline stem cell asymmetric division" ;
rdfs:comment "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes." ;
rdfs:subClassOf obo:GO_0008356 , obo:GO_0042078 , obo:GO_0098722 .
obo:CHEBI_37624 a rdfs:Class ;
rdfs:label "L-glucose" ;
rdfs:subClassOf obo:CHEBI_17234 .
obo:PHIPO_0000548 a rdfs:Class ;
rdfs:label "resistance to hygromycin B"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to hygromycin B. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001396 a rdfs:Class ;
rdfs:label "normal growth on trifloxystrobin" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to trifloxystrobin (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PHIPO_0000732 a rdfs:Class ;
rdfs:label "sensitive to doripenem"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to doripenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000819 .
obo:PHIPO_0000329 a rdfs:Class ;
rdfs:label "sensitive to cyproconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cyproconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0010892 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial translation in response to stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0032056 , obo:GO_0065007 , obo:GO_0070131 .
obo:UBERON_0007243 a rdfs:Class ;
rdfs:label "tunica media of vein" ;
rdfs:comment "A tunica media that is part of a vein." ;
rdfs:subClassOf obo:UBERON_0002522 .
obo:PHIPO_0000280 a rdfs:Class ;
rdfs:label "pathogen effector mediated modulation of host immune system process"@en ;
rdfs:comment "A phenotype dependent on an interaction between a pathogen effector and a host process in order for the pathogen to activate or suppress the host immune system. An effector is an entity derived from a pathogenic or non-pathogenic species that either activates or suppresses host defenses or other host responses." ;
rdfs:subClassOf obo:PHIPO_0001167 .
obo:PHIPO_0000361 a rdfs:Class ;
rdfs:label "delayed pathogen penetration into host"@en ;
rdfs:comment "A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism begins later than normal." ;
rdfs:subClassOf obo:PHIPO_0000331 .
obo:GO_0097054 a rdfs:Class ;
rdfs:label "L-glutamate biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid." ;
rdfs:subClassOf obo:GO_0006536 , obo:GO_0009058 , obo:GO_0009084 , obo:GO_0043650 .
obo:GO_0045933 a rdfs:Class ;
rdfs:label "positive regulation of muscle contraction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of muscle contraction." ;
rdfs:subClassOf obo:GO_0006937 , obo:GO_0051240 , obo:GO_0065007 .
obo:CHEBI_39217 a rdfs:Class ;
rdfs:label "antibiotic nematicide" ;
rdfs:subClassOf obo:CHEBI_25491 , obo:CHEBI_39215 .
obo:GO_0032222 a rdfs:Class ;
rdfs:label "regulation of synaptic transmission, cholinergic" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 .
obo:PHIPO_0000541 a rdfs:Class ;
rdfs:label "resistance to benznidazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to benznidazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PR_P01831 a rdfs:Class ;
rdfs:label "Thy-1 membrane glycoprotein (mouse)" ;
rdfs:comment "A Thy-1 membrane glycoprotein that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001843 , obo:PR_000029032 .
obo:GO_1904707 a rdfs:Class ;
rdfs:label "positive regulation of vascular associated smooth muscle cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0048661 , obo:GO_0065007 , obo:GO_1904705 .
obo:CHEBI_53665 a rdfs:Class ;
rdfs:label "oxazinoquinoline" ;
rdfs:comment "Any organic heterotricyclic compound based on a skeleton comprised of an oxazine ring fused onto a quinoline system." ;
rdfs:subClassOf obo:CHEBI_26979 .
obo:CL_0000134 a rdfs:Class ;
rdfs:label "mesenchymal stem cell" ;
rdfs:comment "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." ;
rdfs:subClassOf obo:CL_0000048 , obo:CL_0002320 .
obo:UBERON_0001737 a rdfs:Class ;
rdfs:label "larynx" ;
rdfs:comment "A continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." ;
rdfs:subClassOf obo:UBERON_0000072 .
obo:GO_0000011 a rdfs:Class ;
rdfs:label "vacuole inheritance" ;
rdfs:comment "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton." ;
rdfs:subClassOf obo:GO_0007033 , obo:GO_0048308 .
obo:PHIPO_0001452 a rdfs:Class ;
rdfs:label "BAX-induced cell death absent"@en ;
rdfs:comment "A single species phenotype in which the cell death typically triggered by the expression or activity of the pro-apoptotic protein BAX is completely abolished." ;
rdfs:subClassOf obo:PHIPO_0000446 .
obo:CHEBI_25000 a rdfs:Class ;
rdfs:label "lactone" ;
rdfs:comment "Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." ;
rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_38104 .
obo:GO_0042402 a rdfs:Class ;
rdfs:label "biogenic amine catabolic process" ;
rdfs:comment "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ;
rdfs:subClassOf obo:GO_0009310 .
obo:UBERON_0007303 a rdfs:Class ;
rdfs:label "pharyngeal vasculature" ;
rdfs:comment "A vasculature that is part of a chordate pharynx." ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0006876 .
obo:GO_0061072 a rdfs:Class ;
rdfs:label "iris morphogenesis" ;
rdfs:comment "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_33245 a rdfs:Class ;
rdfs:label "organic fundamental parent" ;
rdfs:comment "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." ;
rdfs:subClassOf obo:CHEBI_37175 , obo:CHEBI_50860 .
obo:UBERON_0006098 a rdfs:Class ;
rdfs:label "basal nuclear complex" ;
rdfs:comment "The deep nuclei of telencephalic origin found in the basal region of the forebrain." ;
rdfs:subClassOf obo:UBERON_0007245 , obo:UBERON_0019264 .
obo:UBERON_0011158 a rdfs:Class ;
rdfs:label "primary subdivision of skull" ;
rdfs:comment "The skull can be divided into two: the neurocranium and the facial skeleton." ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:CHEBI_50183 a rdfs:Class ;
rdfs:label "P450 inhibitor" ;
rdfs:comment "An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances." ;
rdfs:subClassOf obo:CHEBI_76898 .
obo:CHEBI_46633 a rdfs:Class ;
rdfs:label "carbapenems" ;
rdfs:comment "The class of β-lactam antibiotics that whose members have a carbapenem skeleton which is variously substituted at positions 3, 4, and 6." ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_27933 .
obo:PHIPO_0000892 a rdfs:Class ;
rdfs:label "sensitive to boscalid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to boscalid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1901136 a rdfs:Class ;
rdfs:label "carbohydrate derivative catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_1901135 .
obo:GO_0050995 a rdfs:Class ;
rdfs:label "negative regulation of lipid catabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0045833 , obo:GO_0050994 , obo:GO_0065007 .
obo:CHEBI_17296 a rdfs:Class ;
rdfs:label "aniline" ;
rdfs:comment "A primary arylamine in which an amino functional group is substituted for one of the benzene hydrogens." ;
rdfs:subClassOf obo:CHEBI_22562 , obo:CHEBI_50471 .
obo:CHEBI_17568 a rdfs:Class ;
rdfs:label "uracil" ;
rdfs:comment "A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription." ;
rdfs:subClassOf obo:CHEBI_26432 , obo:CHEBI_38337 , obo:CHEBI_38387 .
obo:UBERON_0018239 a rdfs:Class ;
rdfs:label "rhombomere boundary" ;
rdfs:comment "A boundary delimiting a rhombomere." ;
rdfs:subClassOf obo:UBERON_0007651 .
obo:CL_4307108 a rdfs:Class ;
rdfs:label "MOL NN_4 Sspo mature myelinating oligodendrocyte (Mmus)" ;
rdfs:comment "A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mog (Mmus), Anln (Mmus), Gm32633 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Sspo, Selenop. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5288 MOL NN_4." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301614 .
obo:UBERON_0005740 a rdfs:Class ;
rdfs:label "tunica intima of artery" ;
rdfs:comment "A tunica intima that is part of a artery." ;
rdfs:subClassOf obo:UBERON_0002523 , obo:UBERON_0004797 .
obo:GO_1901692 a rdfs:Class ;
rdfs:label "regulation of compound eye retinal cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:UBERON_0004015 a rdfs:Class ;
rdfs:label "embryonic-extraembryonic boundary" ;
rdfs:comment "The connection between the embryo proper and extraembryonic tissues." ;
rdfs:subClassOf obo:UBERON_0000015 .
obo:GO_0010453 a rdfs:Class ;
rdfs:label "regulation of cell fate commitment" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0010762 a rdfs:Class ;
rdfs:label "regulation of fibroblast migration" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:PHIPO_0000387 a rdfs:Class ;
rdfs:label "resistance to terbinafine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to terbinafine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0005075 a rdfs:Class ;
rdfs:label "forebrain-midbrain boundary" ;
rdfs:comment "An anatomical boundary that adjacent_to a forebrain and adjacent_to a midbrain." ;
rdfs:subClassOf obo:UBERON_0007651 .
obo:GO_0032330 a rdfs:Class ;
rdfs:label "regulation of chondrocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0061035 , obo:GO_0065007 .
obo:CHEBI_53662 a rdfs:Class ;
rdfs:label "biguanides" ;
rdfs:comment "A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton." ;
rdfs:subClassOf obo:CHEBI_24436 .
obo:CL_0000878 a rdfs:Class ;
rdfs:label "central nervous system macrophage" ;
rdfs:comment "A tissue-resident macrophage found in the central nervous system." ;
rdfs:subClassOf obo:CL_0000864 , obo:CL_0002319 .
obo:GO_0051658 a rdfs:Class ;
rdfs:label "maintenance of nucleus location" ;
rdfs:comment "Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0051647 , obo:GO_0051651 , obo:GO_0051657 .
obo:CHEBI_17608 a rdfs:Class ;
rdfs:label "D-aldohexose" ;
rdfs:comment "Any D-aldose having a chain of six carbon atoms in the molecule." ;
rdfs:subClassOf obo:CHEBI_33917 , obo:CHEBI_4194 .
obo:PHIPO_0001012 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction polysaccharide localization phenotype" ;
rdfs:comment "A pathogen host interaction phenotype which affects the localization of a polysaccharide in a pathogen or host cell is abnormal. This includes any process in which a polysaccharide is transported to, or maintained in, a specific location. (GO:0033037)." .
obo:GO_0045124 a rdfs:Class ;
rdfs:label "regulation of bone resorption" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of bone tissue loss (resorption)." ;
rdfs:subClassOf obo:GO_0046850 , obo:GO_0065007 .
obo:PHIPO_0000229 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction biosynthesis of deoxynivalenol" ;
rdfs:comment "A pathogen host interaction phenotype in which the pathogen biosynthesis of deoxynivalenol is abnormal (i.e. different than the wild type)." .
obo:UBERON_0003384 a rdfs:Class ;
rdfs:label "skeletal muscle tissue of pharynx" ;
rdfs:comment "A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001134 , obo:UBERON_0004830 .
obo:UBERON_0003310 a rdfs:Class ;
rdfs:label "floor plate of metencephalon" ;
rdfs:comment "A floor plate that is part of a metencephalon [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0002616 , obo:UBERON_0003306 .
obo:CHEBI_33296 a rdfs:Class ;
rdfs:label "alkali metal molecular entity" ;
rdfs:comment "A molecular entity containing one or more atoms of an alkali metal." ;
rdfs:subClassOf obo:CHEBI_33674 .
obo:UBERON_0005281 a rdfs:Class ;
rdfs:label "ventricular system of central nervous system" ;
rdfs:comment "A set of structures containing cerebrospinal fluid in the brain. It is continuous with the central canal of the spinal cord[WP]." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:PHIPO_0000559 a rdfs:Class ;
rdfs:label "resistance to latrunculin A"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to latrunculin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0001776 a rdfs:Class ;
rdfs:label "optic choroid" ;
rdfs:comment "Vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]." ;
rdfs:subClassOf obo:UBERON_0002203 .
obo:UBERON_0005656 a rdfs:Class ;
rdfs:label "lens vesicle epithelium" ;
rdfs:comment "An epithelium that is part of a lens vesicle." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:PHIPO_0001118 a rdfs:Class ;
rdfs:label "abnormal protein modification"@en ;
rdfs:comment "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is abnormal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." ;
rdfs:subClassOf obo:PHIPO_0000929 .
obo:UBERON_0001508 a rdfs:Class ;
rdfs:label "arch of aorta" ;
rdfs:comment "The convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery." ;
rdfs:subClassOf obo:UBERON_0001515 .
obo:BFO_0000001 a rdfs:Class ;
rdfs:label "entity"@en .
obo:CL_0001061 a rdfs:Class ;
rdfs:label "abnormal cell" ;
rdfs:comment "A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models." ;
rdfs:subClassOf obo:CL_0000000 .
obo:PHIPO_0000577 a rdfs:Class ;
rdfs:label "resistance to nikkomycin Z"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to nikkomycin Z. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000318 a rdfs:Class ;
rdfs:label "obsolete abnormal effector of virulence suppression of host defense" ;
rdfs:comment "The host defenses suppressed by the pathogen are altered compare to the wild type interaction" .
obo:CHEBI_33860 a rdfs:Class ;
rdfs:label "aromatic amine" ;
rdfs:comment "An amino compound in which the amino group is linked directly to an aromatic system." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_50047 .
obo:GO_0007026 a rdfs:Class ;
rdfs:label "negative regulation of microtubule depolymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." ;
rdfs:subClassOf obo:GO_0031111 , obo:GO_0031114 , obo:GO_0065007 , obo:GO_1901880 , obo:GO_1902904 .
obo:GO_0048935 a rdfs:Class ;
rdfs:label "peripheral nervous system neuron development" ;
rdfs:comment "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." ;
rdfs:subClassOf obo:GO_0048468 , obo:GO_0048666 .
obo:GO_0043572 a rdfs:Class ;
rdfs:label "plastid fission" ;
rdfs:comment "The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA." ;
rdfs:subClassOf obo:GO_0048285 .
obo:PATO_0010001 a rdfs:Class ;
rdfs:label "disconnected" ;
rdfs:comment "A structural quality inhering in the bearer by virtue of the bearer consisting of multiple structures lacking any physical connection to each other." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:GO_0046852 a rdfs:Class ;
rdfs:label "positive regulation of bone remodeling" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of bone remodeling." ;
rdfs:subClassOf obo:GO_0034105 , obo:GO_0046850 , obo:GO_0065007 .
obo:CHEBI_48891 a rdfs:Class ;
rdfs:label "thiazolidinone" ;
rdfs:subClassOf obo:CHEBI_35622 .
obo:PHIPO_0001034 a rdfs:Class ;
rdfs:label "substance absent from cell"@en ;
rdfs:comment "A single species cell phenotype in which the amount of a specific substance measured in a cell is too low to detect." ;
rdfs:subClassOf obo:PHIPO_0001035 .
obo:PATO_0000070 a rdfs:Class ;
rdfs:label "amount" ;
rdfs:comment "The number of entities of this type that are part of the whole organism." ;
rdfs:subClassOf obo:PATO_0103000 .
obo:CHEBI_77194 a rdfs:Class ;
rdfs:label "EC 2.7.1.33 (pantothenate kinase) inhibitor" ;
rdfs:comment "An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pantothenate kinase (EC 2.7.1.33)." ;
rdfs:subClassOf obo:CHEBI_76881 .
obo:PHIPO_0000350 a rdfs:Class ;
rdfs:label "absence of pathogen growth on host surface"@en ;
rdfs:comment "A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is absent." ;
rdfs:subClassOf obo:PHIPO_0000188 .
obo:UBERON_0002275 a rdfs:Class ;
rdfs:label "reticular formation" ;
rdfs:comment "A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 )." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:PHIPO_0001310 a rdfs:Class ;
rdfs:label "normal growth on carbendazim"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to carbendazim (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_51144 a rdfs:Class ;
rdfs:label "nitrogen group" ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:GO_0098642 a rdfs:Class ;
rdfs:label "network-forming collagen trimer" ;
rdfs:comment "A collagen trimer that forms networks." ;
rdfs:subClassOf obo:GO_0005581 , obo:GO_0140392 .
obo:CHEBI_53676 a rdfs:Class ;
rdfs:label "ceftazidime(1-)" ;
rdfs:comment "A cephalosporin carboxylic acid anion formed by proton loss from the carboxy group of ceftazidime, a cephalosporin having 7β-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino and 3-pyridinium-1-ylmethyl side-groups." ;
rdfs:subClassOf obo:CHEBI_52440 .
obo:UBERON_0002129 a rdfs:Class ;
rdfs:label "cerebellar cortex" ;
rdfs:comment "The superficial gray matter of the cerebellum. It consists of three main layers, the molecular layer, the Purkinje cell layer and the granule cell layer." ;
rdfs:subClassOf obo:UBERON_0019263 .
obo:CL_4300029 a rdfs:Class ;
rdfs:label "cerebellar glutamatergic neuron (Mmus)" ;
rdfs:comment "A cerebellum glutamatergic neuron of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:29 CB Glut." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_2000028 .
obo:GO_0007041 a rdfs:Class ;
rdfs:label "lysosomal transport" ;
rdfs:comment "The directed movement of substances into, out of or within a lysosome." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0007034 .
obo:GO_0045901 a rdfs:Class ;
rdfs:label "positive regulation of translational elongation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translational elongation." ;
rdfs:subClassOf obo:GO_0006448 , obo:GO_0045727 , obo:GO_0065007 .
obo:GO_0071826 a rdfs:Class ;
rdfs:label "protein-RNA complex organization" ;
rdfs:comment "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0043933 .
obo:CL_4310135 a rdfs:Class ;
rdfs:label "STR Cholinergic GABA striatal cholinergic-GABAergic neuron (Primate)" ;
rdfs:comment "A striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR Cholinergic GABA." ;
rdfs:subClassOf obo:CL_0020008 .
obo:PATO_0070044 a rdfs:Class ;
rdfs:label "anatomical structure quality" ;
rdfs:comment "A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:GO_0003824 a rdfs:Class ;
rdfs:label "catalytic activity" ;
rdfs:comment "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." ;
rdfs:subClassOf obo:GO_0003674 .
obo:UBERON_0004374 a rdfs:Class ;
rdfs:label "vitelline vasculature" ;
rdfs:comment "Vascular network that is connected to the yolk sac." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:GO_0099500 a rdfs:Class ;
rdfs:label "vesicle fusion to plasma membrane" ;
rdfs:comment "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." ;
rdfs:subClassOf obo:GO_0006906 , obo:GO_0061025 , obo:GO_0140029 .
obo:GO_0012506 a rdfs:Class ;
rdfs:label "vesicle membrane" ;
rdfs:comment "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031090 .
obo:GO_0051647 a rdfs:Class ;
rdfs:label "nucleus localization" ;
rdfs:comment "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051640 .
obo:GO_0005496 a rdfs:Class ;
rdfs:label "steroid binding" ;
rdfs:comment "Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0008289 .
obo:GO_0098906 a rdfs:Class ;
rdfs:label "regulation of Purkinje myocyte action potential" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0050789 , obo:GO_0098901 .
obo:GO_0010976 a rdfs:Class ;
rdfs:label "positive regulation of neuron projection development" ;
rdfs:comment "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ;
rdfs:subClassOf obo:GO_0010975 , obo:GO_0031346 , obo:GO_0065007 .
obo:GO_0098867 a rdfs:Class ;
rdfs:label "intramembranous bone growth" ;
rdfs:comment "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone." ;
rdfs:subClassOf obo:GO_0048589 , obo:GO_0098868 .
obo:GO_0099118 a rdfs:Class ;
rdfs:label "microtubule-based protein transport" ;
rdfs:comment "A microtubule-based process that results in the transport of proteins." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0007017 , obo:GO_0015031 , obo:GO_0099111 .
obo:CHEBI_209807 a rdfs:Class ;
rdfs:label "cefoxitin" ;
rdfs:comment "A semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7α position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to β-lactamase." ;
rdfs:subClassOf obo:CHEBI_23003 , obo:CHEBI_23066 , obo:CHEBI_55429 , obo:CHEBI_72588 , obo:CHEBI_88225 .
obo:CL_0000604 a rdfs:Class ;
rdfs:label "retinal rod cell" ;
rdfs:comment "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." ;
rdfs:subClassOf obo:CL_0010009 .
obo:CHEBI_52210 a rdfs:Class ;
rdfs:label "pharmacological role" ;
rdfs:comment "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:PHIPO_0001367 a rdfs:Class ;
rdfs:label "normal growth on bixafen" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to bixafen (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_1904267 a rdfs:Class ;
rdfs:label "negative regulation of Schwann cell chemotaxis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis." ;
rdfs:subClassOf obo:GO_0050922 , obo:GO_0065007 , obo:GO_1900148 , obo:GO_1904266 .
obo:GO_0043648 a rdfs:Class ;
rdfs:label "dicarboxylic acid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0019752 .
obo:PHIPO_0000941 a rdfs:Class ;
rdfs:label "short germ tube"@en ;
rdfs:comment "A single species phenotype where the slender tubular outgrowth first produced by most spores in germination is shorter than normal. (GO:0032179)" ;
rdfs:subClassOf obo:PHIPO_0000940 .
obo:PHIPO_0000279 a rdfs:Class ;
rdfs:label "obsolete systemic phenotype" .
obo:GO_0060297 a rdfs:Class ;
rdfs:label "regulation of sarcomere organization" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0110020 , obo:GO_1902903 .
obo:UBERON_0010719 a rdfs:Class ;
rdfs:label "girdle skeleton" ;
rdfs:comment "The subdivision of the skeleton of either the pectoral or pelvic girdle." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:CHEBI_64459 a rdfs:Class ;
rdfs:label "biaryl" ;
rdfs:comment "An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond." ;
rdfs:subClassOf obo:CHEBI_33659 .
obo:GO_0045844 a rdfs:Class ;
rdfs:label "positive regulation of striated muscle tissue development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of striated muscle development." ;
rdfs:subClassOf obo:GO_0016202 , obo:GO_0048636 , obo:GO_0065007 , obo:GO_1901863 .
obo:PATO_0001591 a rdfs:Class ;
rdfs:label "curvature" ;
rdfs:comment "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:CL_0000068 a rdfs:Class ;
rdfs:label "duct epithelial cell" ;
rdfs:comment "An epithelial cell that is part of a duct." ;
rdfs:subClassOf obo:CL_0000066 .
obo:UBERON_0007616 a rdfs:Class ;
rdfs:label "layer of synovial tissue" ;
rdfs:comment "A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]." ;
rdfs:subClassOf obo:UBERON_0000042 .
obo:GO_0002442 a rdfs:Class ;
rdfs:label "serotonin secretion involved in inflammatory response" ;
rdfs:comment "The regulated release of serotonin by a cell as part of an inflammatory response." ;
rdfs:subClassOf obo:GO_0001820 .
obo:UBERON_0003593 a rdfs:Class ;
rdfs:label "thoracic cavity connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:CHEBI_230471 a rdfs:Class ;
rdfs:label "EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitor" ;
rdfs:comment "A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of 1,3-β-glucan synthase (EC 2.4.1.34)." ;
rdfs:subClassOf obo:CHEBI_76789 .
obo:CHEBI_48219 a rdfs:Class ;
rdfs:label "disinfectant" ;
rdfs:comment "An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity." ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:GO_0003273 a rdfs:Class ;
rdfs:label "cell migration involved in endocardial cushion formation" ;
rdfs:comment "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0060973 .
obo:UBERON_0001568 a rdfs:Class ;
rdfs:label "muscle of larynx" ;
rdfs:comment "The muscles associated with the larynx." ;
rdfs:subClassOf obo:UBERON_0002377 , obo:UBERON_0003831 , obo:UBERON_0014892 .
obo:PHIPO_0000097 a rdfs:Class ;
rdfs:label "abnormal meiosis I"@en ;
rdfs:comment "A reproductive process phenotype in which the first meiotic nuclear division is abnormal (GO:0007127)." ;
rdfs:subClassOf obo:PHIPO_0000981 .
obo:GO_0045947 a rdfs:Class ;
rdfs:label "negative regulation of translational initiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0017148 , obo:GO_0065007 .
obo:CHEBI_36358 a rdfs:Class ;
rdfs:label "polyatomic ion" ;
rdfs:comment "An ion consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_24870 , obo:CHEBI_36357 .
obo:PATO_0001549 a rdfs:Class ;
rdfs:label "increased sensitivity toward" ;
rdfs:comment "A sensitivity toward an external stimulus which is higher than normal/average." ;
rdfs:subClassOf obo:PATO_0000516 , obo:PATO_0002305 .
obo:GO_0003330 a rdfs:Class ;
rdfs:label "regulation of extracellular matrix constituent secretion" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903053 , obo:GO_1903530 .
obo:CHEBI_53655 a rdfs:Class ;
rdfs:label "cefoxitin(1-)" ;
rdfs:comment "A cephalosporin carboxylic acid anion having methoxy, 2-thienylacetamido and carbamoyloxymethyl side-groups, formed by proton loss from the carboxy group of the semisynthetic cephamycin antibiotic cefoxitin." ;
rdfs:subClassOf obo:CHEBI_52440 .
a rdfs:Class ;
rdfs:label "Cerebellar cortex, granular layer" ;
rdfs:subClassOf , obo:UBERON_0002956 .
obo:GO_1900127 a rdfs:Class ;
rdfs:label "positive regulation of hyaluronan biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process." ;
rdfs:subClassOf obo:GO_0010557 , obo:GO_0045913 , obo:GO_0065007 , obo:GO_1900125 .
obo:GO_0005911 a rdfs:Class ;
rdfs:label "cell-cell junction" ;
rdfs:comment "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." ;
rdfs:subClassOf obo:GO_0070161 .
obo:CHEBI_86426 a rdfs:Class ;
rdfs:label "triazole antifungal agent" ;
rdfs:comment "A member of the class of triazole that has significant antifungal properties." ;
rdfs:subClassOf obo:CHEBI_35727 .
obo:GO_0021826 a rdfs:Class ;
rdfs:label "substrate-independent telencephalic tangential migration" ;
rdfs:comment "The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact." ;
rdfs:subClassOf obo:GO_0022029 .
obo:UBERON_0011137 a rdfs:Class ;
rdfs:label "axial skeletal system" ;
rdfs:comment "Subdivision of the skeletal system which consists of the axial skeleton plus associated joints." ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:PHIPO_0000510 a rdfs:Class ;
rdfs:label "pathogen host interaction cell phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype that is observed at the level of an individual cell." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:CHEBI_33285 a rdfs:Class ;
rdfs:label "heteroorganic entity" ;
rdfs:comment "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:GO_0005604 a rdfs:Class ;
rdfs:label "basement membrane" ;
rdfs:comment "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." ;
rdfs:subClassOf obo:GO_0031012 .
obo:GO_2000288 a rdfs:Class ;
rdfs:label "positive regulation of myoblast proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of myoblast proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0065007 , obo:GO_2000291 .
obo:GO_0048711 a rdfs:Class ;
rdfs:label "positive regulation of astrocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of astrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045687 , obo:GO_0048710 , obo:GO_0065007 .
obo:CHEBI_64355 a rdfs:Class ;
rdfs:label "posaconazole" ;
rdfs:comment "An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug." ;
rdfs:subClassOf obo:CHEBI_26912 , obo:CHEBI_35618 , obo:CHEBI_37143 , obo:CHEBI_46848 , obo:CHEBI_87071 , obo:CHEBI_87101 .
obo:GO_1903326 a rdfs:Class ;
rdfs:label "regulation of tRNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of tRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051252 , obo:GO_0065007 .
obo:UBERON_0016490 a rdfs:Class ;
rdfs:label "auditory system" ;
rdfs:comment "Is the sensory system for the sense of hearing." ;
rdfs:subClassOf obo:UBERON_0001032 , obo:UBERON_0007037 .
obo:UBERON_0019319 a rdfs:Class ;
rdfs:label "exocrine gland of integumental system" ;
rdfs:comment "An exocrine gland that is part of a integumental system." ;
rdfs:subClassOf obo:UBERON_0002365 , obo:UBERON_0003297 .
obo:PHIPO_0001240 a rdfs:Class ;
rdfs:label "host defense induced alkalization present"@en ;
rdfs:comment "A pathogen host interaction phenotype where the host induces a pH increase in response to pathogen colonization." ;
rdfs:subClassOf obo:PHIPO_0001108 .
obo:GO_0002280 a rdfs:Class ;
rdfs:label "monocyte activation involved in immune response" ;
rdfs:comment "The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0002275 , obo:GO_0042117 .
obo:PHIPO_0000291 a rdfs:Class ;
rdfs:label "obsolete colour absent" .
obo:GO_1901532 a rdfs:Class ;
rdfs:label "regulation of hematopoietic progenitor cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:CHEBI_23449 a rdfs:Class ;
rdfs:label "cyclic peptide" ;
rdfs:subClassOf obo:CHEBI_16670 .
obo:CL_0000404 a rdfs:Class ;
rdfs:label "electrically signaling cell" ;
rdfs:comment "A cell that initiates an electrical signal and passes that signal to another cell." ;
rdfs:subClassOf obo:CL_0000211 .
obo:GO_0009887 a rdfs:Class ;
rdfs:label "animal organ morphogenesis" ;
rdfs:comment "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_2000147 a rdfs:Class ;
rdfs:label "positive regulation of cell motility" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell motility." ;
rdfs:subClassOf obo:GO_0040017 , obo:GO_0048522 , obo:GO_0065007 , obo:GO_2000145 .
obo:GO_0099575 a rdfs:Class ;
rdfs:label "regulation of protein catabolic process at presynapse, modulating synaptic transmission" ;
rdfs:comment "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." ;
rdfs:subClassOf obo:GO_0042176 , obo:GO_0099171 .
obo:CHEBI_35715 a rdfs:Class ;
rdfs:label "nitro compound" ;
rdfs:comment "A compound having a nitro group, ‒NO2 (free valence on nitrogen), which may be attached to carbon, nitrogen (as in nitramines), or oxygen (as in nitrates), among other elements (in the absence of specification, C-nitro compounds are usually implied)." ;
rdfs:subClassOf obo:CHEBI_51143 .
obo:GO_0003211 a rdfs:Class ;
rdfs:label "cardiac ventricle formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." ;
rdfs:subClassOf obo:GO_0003207 , obo:GO_0048646 .
obo:CL_0000235 a rdfs:Class ;
rdfs:label "macrophage" ;
rdfs:comment "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." ;
rdfs:subClassOf obo:CL_0000113 , obo:CL_0000145 , obo:CL_0000766 .
obo:PHIPO_0001437 a rdfs:Class ;
rdfs:label "normal growth on terbinafine" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to terbinafine (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PHIPO_0001280 a rdfs:Class ;
rdfs:label "increased pathogen induced host DNA synthesis"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the host DNA synthesis during pathogen infection occurs to a greater extent than normal (GO:0090592 DNA synthesis involved in DNA replication)." ;
rdfs:subClassOf obo:PHIPO_0001247 .
obo:PHIPO_0000381 a rdfs:Class ;
rdfs:label "resistance to benomyl"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to benomyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0003290 a rdfs:Class ;
rdfs:label "meninx of diencephalon" ;
rdfs:comment "A meninx that is part of a diencephalon [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002360 , obo:UBERON_0003548 .
obo:UBERON_0002216 a rdfs:Class ;
rdfs:label "symphysis" ;
rdfs:comment "Cartilaginous joint in which the articulating bones or cartilages are connected by fibrocartilage. Examples: pubic symphysis, intervertebral symphysis, manubriosternal joint.[FMA]." ;
rdfs:subClassOf obo:UBERON_0002209 , obo:UBERON_0002213 .
obo:CLM_1000083 a rdfs:Class ;
rdfs:label "NS forest marker set of sst chodl GABAergic interneuron (Human neocortex)." ;
rdfs:subClassOf obo:SO_0001260 .
obo:UBERON_0001043 a rdfs:Class ;
rdfs:label "esophagus" ;
rdfs:comment "Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)." ;
rdfs:subClassOf obo:UBERON_0004921 , obo:UBERON_0013765 .
obo:CHEBI_18059 a rdfs:Class ;
rdfs:label "lipid" ;
rdfs:comment "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:CHEBI_35689 a rdfs:Class ;
rdfs:label "tetrazoles" ;
rdfs:comment "An azole in which the five-membered heterocyclic aromatic skeleton contains four N atoms and one C atom." ;
rdfs:subClassOf obo:CHEBI_68452 .
obo:PATO_0001579 a rdfs:Class ;
rdfs:label "contractility" ;
rdfs:comment "A physical quality that is the ability to contract or shrink." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:CL_0000022 a rdfs:Class ;
rdfs:label "female germ line stem cell" ;
rdfs:comment "A stem cell that is the precursor of female gametes." ;
rdfs:subClassOf obo:CL_0000014 , obo:CL_0000021 .
obo:CHEBI_33461 a rdfs:Class ;
rdfs:label "phosphorus oxoanion" ;
rdfs:subClassOf obo:CHEBI_24834 , obo:CHEBI_26082 , obo:CHEBI_33459 .
obo:PHIPO_0000324 a rdfs:Class ;
rdfs:label "obsolete abnormal effector of pathogenicity suppression of host defense" ;
rdfs:comment "The host defenses suppressed by the pathogen are altered compared to the wild type interaction" .
obo:GO_0021999 a rdfs:Class ;
rdfs:label "neural plate anterior/posterior regionalization" ;
rdfs:comment "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate." ;
rdfs:subClassOf obo:GO_0009952 , obo:GO_0060897 .
obo:GO_0140131 a rdfs:Class ;
rdfs:label "positive regulation of lymphocyte chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0002690 , obo:GO_0065007 , obo:GO_1901623 , obo:GO_2000403 .
obo:PHIPO_0000608 a rdfs:Class ;
rdfs:label "resistance to rifabutin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to rifabutin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_4310113 a rdfs:Class ;
rdfs:label "SN GATA3-PVALB GABA GABAergic neuron (Primate)" ;
rdfs:comment "A GABAergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN GATA3-PVALB GABA." ;
rdfs:subClassOf obo:CL_0000617 .
obo:UBERON_0001134 a rdfs:Class ;
rdfs:label "skeletal muscle tissue" ;
rdfs:comment "Muscle tissue that consists primarily of skeletal muscle fibers." ;
rdfs:subClassOf obo:UBERON_0002036 , obo:UBERON_0002385 .
obo:GO_0043558 a rdfs:Class ;
rdfs:label "regulation of translational initiation in response to stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0043555 , obo:GO_0065007 .
obo:PHIPO_0000711 a rdfs:Class ;
rdfs:label "resistance to camptothecin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to camptothecin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0070199 a rdfs:Class ;
rdfs:label "establishment of protein localization to chromosome" ;
rdfs:comment "The directed movement of a protein to a specific location on a chromosome." ;
rdfs:subClassOf obo:GO_0034502 , obo:GO_0045184 , obo:GO_0072594 .
obo:CHEBI_63353 a rdfs:Class ;
rdfs:label "disaccharide derivative" ;
rdfs:comment "A carbohydrate derivative that is formally obtained from a disaccharide." ;
rdfs:subClassOf obo:CHEBI_63299 .
obo:UBERON_0013701 a rdfs:Class ;
rdfs:label "main body axis" ;
rdfs:comment "A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages." ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:UBERON_0034923 a rdfs:Class ;
rdfs:label "disconnected anatomical group" ;
rdfs:comment "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:GO_0050765 a rdfs:Class ;
rdfs:label "negative regulation of phagocytosis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis." ;
rdfs:subClassOf obo:GO_0045806 , obo:GO_0050764 , obo:GO_0065007 .
obo:GO_1902865 a rdfs:Class ;
rdfs:label "positive regulation of embryonic camera-type eye development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_1902863 .
obo:CL_4023051 a rdfs:Class ;
rdfs:label "vascular leptomeningeal cell" ;
rdfs:comment "A transcriptomically distinct type of mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Non-neuronal cells', Author Categories: 'CrossArea_subclass', clusters VLMC." ;
rdfs:subClassOf obo:CL_4023058 .
obo:CL_1000330 a rdfs:Class ;
rdfs:label "serous cell of epithelium of trachea" ;
rdfs:comment "A serous secreting cell that is part of the epithelium of trachea." ;
rdfs:subClassOf obo:CL_0000313 , obo:CL_0019001 .
obo:GO_0090289 a rdfs:Class ;
rdfs:label "regulation of osteoclast proliferation" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070663 .
obo:GO_0060414 a rdfs:Class ;
rdfs:label "aorta smooth muscle tissue morphogenesis" ;
rdfs:comment "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060415 .
obo:GO_1905720 a rdfs:Class ;
rdfs:label "cytoplasmic microtubule bundle" ;
rdfs:comment "Any microtubule bundle that is part of a cytoplasm." ;
rdfs:subClassOf obo:GO_0097427 .
obo:CL_1000042 a rdfs:Class ;
rdfs:label "forebrain neuroblast" ;
rdfs:comment "Any neuroblast (sensu Vertebrata) that is part of some forebrain." ;
rdfs:subClassOf obo:CL_0000031 , obo:CL_0002319 .
obo:PHIPO_0000461 a rdfs:Class ;
rdfs:label "presence of pathogen-associated host defense induced lesions"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own programmed cell death pathways in defense, is present." ;
rdfs:subClassOf obo:PHIPO_0000480 .
obo:CHEBI_38070 a rdfs:Class ;
rdfs:label "anti-arrhythmia drug" ;
rdfs:comment "A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres." ;
rdfs:subClassOf obo:CHEBI_35554 .
obo:GO_0021692 a rdfs:Class ;
rdfs:label "cerebellar Purkinje cell layer morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0032839 a rdfs:Class ;
rdfs:label "dendrite cytoplasm" ;
rdfs:comment "All of the contents of a dendrite, excluding the surrounding plasma membrane." ;
rdfs:subClassOf obo:GO_0005737 , obo:GO_0120111 .
obo:PATO_0010006 a rdfs:Class ;
rdfs:label "cell morphology" ;
rdfs:comment "A quality of a single cell inhering in the bearer by virtue of the bearer's size or shape or structure." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:GO_0050714 a rdfs:Class ;
rdfs:label "positive regulation of protein secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." ;
rdfs:subClassOf obo:GO_0050708 , obo:GO_0051222 , obo:GO_0065007 , obo:GO_1903532 .
obo:UBERON_0011357 a rdfs:Class ;
rdfs:label "Reissner's fiber" ;
rdfs:comment "An acellular strand that runs from subcommissural organ caudally through the ventricular system and central canal to the ampulla caudalis. Develops from glycoproteins secreted into CSF." ;
rdfs:subClassOf obo:UBERON_0000476 .
obo:CHEBI_51897 a rdfs:Class ;
rdfs:label "carbenicillin(2-)" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:UBERON_0002358 a rdfs:Class ;
rdfs:label "peritoneum" ;
rdfs:comment "A serous membrane that lines the peritoneal cavity[VHOG,modified]." ;
rdfs:subClassOf obo:UBERON_0000042 .
obo:PHIPO_0000648 a rdfs:Class ;
rdfs:label "resistance to miltefosine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to miltefosine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_64049 a rdfs:Class ;
rdfs:label "food acidity regulator" ;
rdfs:comment "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." ;
rdfs:subClassOf obo:CHEBI_64047 .
obo:CL_0002503 a rdfs:Class ;
rdfs:label "adventitial cell" ;
rdfs:comment "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc" ;
rdfs:subClassOf obo:CL_0000630 , obo:CL_0002320 .
obo:CHEBI_17792 a rdfs:Class ;
rdfs:label "organohalogen compound" ;
rdfs:comment "A compound containing at least one carbon-halogen bond (where X is a halogen atom)." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_37578 .
obo:GO_0045833 a rdfs:Class ;
rdfs:label "negative regulation of lipid metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0019216 , obo:GO_0065007 .
obo:CL_0000835 a rdfs:Class ;
rdfs:label "myeloblast" ;
rdfs:comment "The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow." ;
rdfs:subClassOf obo:CL_0000763 , obo:CL_0002191 .
obo:UBERON_0005061 a rdfs:Class ;
rdfs:label "neural groove" ;
rdfs:comment "The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:PHIPO_0001426 a rdfs:Class ;
rdfs:label "normal growth on fludioxonil"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to fludioxonil (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PHIPO_0001023 a rdfs:Class ;
rdfs:label "decreased cellular cAMP level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of cyclic AMP measured in a cell is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001022 , obo:PHIPO_0001035 .
obo:CL_4307053 a rdfs:Class ;
rdfs:label "Astro-OLF NN_2 Slc25a34 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Hs3st3a1 (Mmus), Slc25a34 (Mmus), C4b (Mmus). It is distinguished from other Astro-OLF NN_2 cells by expression of Slc25a34, C4b. These cells are located in the Olfactory areas, brain , in or close to the regions: Main olfactory bulb, outer plexiform layer, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5233 Astro-OLF NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301597 .
obo:GO_0000048 a rdfs:Class ;
rdfs:label "peptidyltransferase activity" ;
rdfs:comment "Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme." ;
rdfs:subClassOf obo:GO_0016755 , obo:GO_0140096 , obo:GO_0140101 .
obo:CHEBI_30803 a rdfs:Class ;
rdfs:label "isophthalate(2-)" ;
rdfs:subClassOf obo:CHEBI_28965 .
obo:GO_1905901 a rdfs:Class ;
rdfs:label "positive regulation of smooth muscle tissue development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901863 , obo:GO_1905899 .
obo:CHEBI_62913 a rdfs:Class ;
rdfs:label "EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor" ;
rdfs:comment "An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD+ ADP-ribosyltransferase (EC 2.4.2.30)." ;
rdfs:subClassOf obo:CHEBI_76790 .
obo:PHIPO_0000352 a rdfs:Class ;
rdfs:label "normal formation of pathogen penetration structure prior to entry into host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the formation of the pathogen penetration structure is normal (i.e indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000949 .
obo:GO_0050905 a rdfs:Class ;
rdfs:label "neuromuscular process" ;
rdfs:comment "Any process pertaining to the functions of the nervous and muscular systems of an organism." ;
rdfs:subClassOf obo:GO_0050877 .
obo:CHEBI_27641 a rdfs:Class ;
rdfs:label "cycloheximide" ;
rdfs:comment "A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus." ;
rdfs:subClassOf obo:CHEBI_35356 , obo:CHEBI_35681 , obo:CHEBI_3992 , obo:CHEBI_48589 , obo:CHEBI_49318 , obo:CHEBI_87114 .
obo:UBERON_0004908 a rdfs:Class ;
rdfs:label "upper digestive tract" ;
rdfs:comment "The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum." ;
rdfs:subClassOf obo:UBERON_0004921 .
obo:UBERON_0000058 a rdfs:Class ;
rdfs:label "duct" ;
rdfs:comment "A tubular structure that transports secreted or excreted substances." ;
rdfs:subClassOf obo:UBERON_0000063 .
obo:GO_1902839 a rdfs:Class ;
rdfs:label "negative regulation of nuclear migration along microtubule" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0065007 , obo:GO_1902838 .
obo:CHEBI_63697 a rdfs:Class ;
rdfs:label "pyrrolidinopiperidine" ;
rdfs:comment "Any organic heterobicyclic compound containing ortho-fused pyrrolidine and piperidine rings." ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 .
obo:CL_4030053 a rdfs:Class ;
rdfs:label "Islands of Calleja granule cell" ;
rdfs:comment "A GABAergic neuron that resides in the islands of calleja and shows the cytoarchitectural and molecular features characteristic of this granule-like cell population. In mice and primates, it expresses D1 and D3 dopamine receptors (Drd1; Drd3), GABAergic markers (GAD1/2) and form densely packed granule cell clusters in the olfactory tubercle within the ventral striatum. Moreover it receives dense dopaminergic input from the VTA, and functionally associated with self-grooming behaviors and depression-like behaviors." ;
rdfs:subClassOf obo:CL_0000120 , obo:CL_0000617 , obo:CL_0002613 .
obo:CHEBI_35705 a rdfs:Class ;
rdfs:label "immunosuppressive agent" ;
rdfs:comment "An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response." ;
rdfs:subClassOf obo:CHEBI_50846 .
obo:CHEBI_23763 a rdfs:Class ;
rdfs:label "pyrroline" ;
rdfs:comment "Any organic heteromonocyclic compound with a structure based on a dihydropyrrole." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:GO_0051094 a rdfs:Class ;
rdfs:label "positive regulation of developmental process" ;
rdfs:comment "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0050793 , obo:GO_0065007 .
obo:GO_1901374 a rdfs:Class ;
rdfs:label "acetate ester transport" ;
rdfs:comment "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 .
obo:GO_0007097 a rdfs:Class ;
rdfs:label "nuclear migration" ;
rdfs:comment "The directed movement of the nucleus to a specific location within a cell." ;
rdfs:subClassOf obo:GO_0046907 , obo:GO_0051647 , obo:GO_0051656 .
obo:GO_0031399 a rdfs:Class ;
rdfs:label "regulation of protein modification process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ;
rdfs:subClassOf obo:GO_0051246 , obo:GO_0065007 .
obo:GO_0090132 a rdfs:Class ;
rdfs:label "epithelium migration" ;
rdfs:comment "The process in which the population of cells that make up an epithelium undergo directed movement." ;
rdfs:subClassOf obo:GO_0090130 .
obo:CHEBI_76736 a rdfs:Class ;
rdfs:label "EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*)." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:UBERON_0010428 a rdfs:Class ;
rdfs:label "flat bone" ;
rdfs:comment "A bone that is shaped as a broad flat plate and composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow." ;
rdfs:subClassOf obo:UBERON_0001474 .
obo:PHIPO_0000398 a rdfs:Class ;
rdfs:label "sensitive to benomyl"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to benomyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0002572 a rdfs:Class ;
rdfs:label "pro-T cell differentiation" ;
rdfs:comment "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed." ;
rdfs:subClassOf obo:GO_0002320 , obo:GO_0030154 .
obo:UBERON_0019304 a rdfs:Class ;
rdfs:label "sensory organ epithelium" ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:UBERON_0002812 a rdfs:Class ;
rdfs:label "left cerebral hemisphere" ;
rdfs:comment "A cerebral hemisphere that is in the left side of a brain." ;
rdfs:subClassOf obo:UBERON_0001869 .
obo:UBERON_0001032 a rdfs:Class ;
rdfs:label "sensory system" ;
rdfs:comment "Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information." ;
rdfs:subClassOf obo:UBERON_0015203 .
obo:CHEBI_63473 a rdfs:Class ;
rdfs:label "aromatic amino-acid anion" ;
rdfs:comment "An aromatic amino acid whose α-carboxylic acid group is ionized (non-protonated)." ;
rdfs:subClassOf obo:CHEBI_37022 .
obo:UBERON_0004363 a rdfs:Class ;
rdfs:label "pharyngeal arch artery" ;
rdfs:comment "One of a series of paired embryological vascular structures formed within a pharyngeal arch; in the adult, some of these vessels give rise to the great vessels[MP]." ;
rdfs:subClassOf obo:UBERON_0003469 , obo:UBERON_0006598 , obo:UBERON_0010314 .
obo:UBERON_0002437 a rdfs:Class ;
rdfs:label "cerebral hemisphere white matter" ;
rdfs:comment "White matter that is part of a cerebral hemisphere." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0011299 .
obo:PHIPO_0000335 a rdfs:Class ;
rdfs:label "normal pathogen cell to cell migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is normal." ;
rdfs:subClassOf obo:PHIPO_0000333 .
obo:UBERON_0003070 a rdfs:Class ;
rdfs:label "trigeminal placode complex" ;
rdfs:comment "A neurogenic placode that arises at the level of the midbrain-hindbrain boundary and develops into a trigeminal ganglion." ;
rdfs:subClassOf obo:UBERON_0003067 .
obo:CHEBI_33838 a rdfs:Class ;
rdfs:label "nucleoside" ;
rdfs:comment "An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents." ;
rdfs:subClassOf obo:CHEBI_21731 , obo:CHEBI_26912 , obo:CHEBI_61120 .
obo:UBERON_0013727 a rdfs:Class ;
rdfs:label "notochordal fluid" ;
rdfs:comment "Fluid contained within the notochordal canal." ;
rdfs:subClassOf obo:UBERON_0006314 .
obo:GO_0048546 a rdfs:Class ;
rdfs:label "digestive tract morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0035239 .
obo:UBERON_0009661 a rdfs:Class ;
rdfs:label "midbrain nucleus" ;
rdfs:comment "Nucleus located in the midbrain." ;
rdfs:subClassOf obo:UBERON_0002308 .
obo:GO_0002819 a rdfs:Class ;
rdfs:label "regulation of adaptive immune response" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of an adaptive immune response." ;
rdfs:subClassOf obo:GO_0050776 , obo:GO_0065007 .
obo:CHEBI_33719 a rdfs:Class ;
rdfs:label "alpha-amino-acid cation" ;
rdfs:subClassOf obo:CHEBI_33703 .
obo:CHEBI_26069 a rdfs:Class ;
rdfs:label "phosphonic acids" ;
rdfs:comment "HP(=O)(OH)2 (phosphonic acid) and its P-substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_36360 .
obo:UBERON_0001434 a rdfs:Class ;
rdfs:label "skeletal system" ;
rdfs:comment "Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:UBERON_0009920 a rdfs:Class ;
rdfs:label "optic neural crest" ;
rdfs:subClassOf obo:UBERON_0005253 , obo:UBERON_0007530 .
obo:CHEBI_22986 a rdfs:Class ;
rdfs:label "calcium ionophore" ;
rdfs:subClassOf obo:CHEBI_24869 .
obo:GO_0060479 a rdfs:Class ;
rdfs:label "lung cell differentiation" ;
rdfs:comment "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0046929 a rdfs:Class ;
rdfs:label "negative regulation of neurotransmitter secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." ;
rdfs:subClassOf obo:GO_0046928 , obo:GO_0051589 , obo:GO_0065007 , obo:GO_1903531 .
obo:CHEBI_46686 a rdfs:Class ;
rdfs:label "azaalkane" ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:UBERON_0000974 a rdfs:Class ;
rdfs:label "neck" ;
rdfs:comment "An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column." ;
rdfs:subClassOf obo:UBERON_0000475 .
a rdf:Property ;
rdfs:label "anteriorly connected to" ;
rdfs:comment "x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y." ;
rdfs:range ;
rdfs:subPropertyOf obo:BSPO_0000099 , obo:RO_0002170 , .
a rdf:Property ;
rdfs:label "posteriorly connected to" ;
rdfs:comment "x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y." ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002170 , obo:BSPO_0000096 .
obo:GO_0019867 a rdfs:Class ;
rdfs:label "outer membrane" ;
rdfs:comment "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites." ;
rdfs:subClassOf obo:GO_0016020 .
obo:PHIPO_0001385 a rdfs:Class ;
rdfs:label "resistance to phenamacril" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to phenamacril. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0010594 a rdfs:Class ;
rdfs:label "regulation of endothelial cell migration" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:PHIPO_0000134 a rdfs:Class ;
rdfs:label "normal protein-protein interaction"@en ;
rdfs:comment "A single species molecular function phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000132 .
obo:UBERON_0000361 a rdfs:Class ;
rdfs:label "red bone marrow" ;
rdfs:comment "The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream." ;
rdfs:subClassOf obo:UBERON_0002371 .
obo:CHEBI_37848 a rdfs:Class ;
rdfs:label "plant hormone" ;
rdfs:comment "A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds." ;
rdfs:subClassOf obo:CHEBI_24621 , obo:CHEBI_26155 .
obo:GO_1904396 a rdfs:Class ;
rdfs:label "regulation of neuromuscular junction development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuromuscular junction development." ;
rdfs:subClassOf obo:GO_0050807 , obo:GO_0065007 .
obo:CHEBI_22323 a rdfs:Class ;
rdfs:label "alkyl group" ;
rdfs:comment "A univalent group ‒CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom." ;
rdfs:subClassOf obo:CHEBI_33248 .
obo:GO_0034643 a rdfs:Class ;
rdfs:label "establishment of mitochondrion localization, microtubule-mediated" ;
rdfs:comment "The directed movement of the mitochondrion to a specific location, by a process involving microtubules." ;
rdfs:subClassOf obo:GO_0007018 , obo:GO_0051234 , obo:GO_0051654 .
obo:GO_0055010 a rdfs:Class ;
rdfs:label "ventricular cardiac muscle tissue morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0055008 .
obo:GO_0032413 a rdfs:Class ;
rdfs:label "negative regulation of ion transmembrane transporter activity" ;
rdfs:comment "Any process that stops or reduces the activity of an ion transporter." ;
rdfs:subClassOf obo:GO_0022898 , obo:GO_0032410 , obo:GO_0034766 , obo:GO_0065007 .
obo:GO_0021550 a rdfs:Class ;
rdfs:label "medulla oblongata development" ;
rdfs:comment "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_33256 a rdfs:Class ;
rdfs:label "primary amide" ;
rdfs:comment "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ;
rdfs:subClassOf obo:CHEBI_32988 .
obo:GO_0014062 a rdfs:Class ;
rdfs:label "regulation of serotonin secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of serotonin." ;
rdfs:subClassOf obo:GO_0043269 , obo:GO_0065007 , obo:GO_1903530 .
obo:GO_1905809 a rdfs:Class ;
rdfs:label "negative regulation of synapse organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization." ;
rdfs:subClassOf obo:GO_0050807 , obo:GO_0051129 , obo:GO_0065007 .
obo:UBERON_0000307 a rdfs:Class ;
rdfs:label "blastula" ;
rdfs:comment "Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." ;
rdfs:subClassOf obo:UBERON_0000468 , obo:UBERON_0000922 .
obo:PATO_0001410 a rdfs:Class ;
rdfs:label "striated" ;
rdfs:comment "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:PHIPO_0000038 a rdfs:Class ;
rdfs:label "mutualism phenotype"@en ;
rdfs:comment "A phenotype which affects the balance of symbiotic mutualism, mutualism describes an interaction between two symbionts (where the larger is usually the host), results in positive (beneficial) effects on reproduction and/or survival of both species." ;
rdfs:subClassOf obo:PHIPO_0001179 .
obo:PHIPO_0001254 a rdfs:Class ;
rdfs:label "decreased host immune inflammatory response with pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection occurs to a lesser extent than normal. (GO:0006954 inflammatory response)." ;
rdfs:subClassOf obo:PHIPO_0001253 .
obo:UBERON_0002302 a rdfs:Class ;
rdfs:label "myocardium of atrium" ;
rdfs:comment "The atrial part of middle layer of the heart, comprised of involuntary muscle." ;
rdfs:subClassOf obo:UBERON_0002349 .
obo:UBERON_0001653 a rdfs:Class ;
rdfs:label "facial vein" ;
rdfs:comment "The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0003496 , obo:UBERON_0009141 .
obo:PHIPO_0001077 a rdfs:Class ;
rdfs:label "decreased cellular melanin accumulation"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of melanin in a cell is decreased." ;
rdfs:subClassOf obo:PHIPO_0000288 .
obo:CL_0000605 a rdfs:Class ;
rdfs:label "fungal asexual spore" ;
rdfs:comment "A spore formed following mitosis or mitoses." ;
rdfs:subClassOf obo:CL_0002369 .
obo:GO_0060131 a rdfs:Class ;
rdfs:label "corticotropin hormone secreting cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:PHIPO_0000099 a rdfs:Class ;
rdfs:label "normal meiosis I"@en ;
rdfs:comment "A reproductive process phenotype in which the first meiotic nuclear division is normal (GO:0007127)." ;
rdfs:subClassOf obo:PHIPO_0000982 .
a rdfs:Class ;
rdfs:label "Brain stem" ;
rdfs:subClassOf , obo:UBERON_0002298 .
obo:CHEBI_60926 a rdfs:Class ;
rdfs:label "amino monosaccharide" ;
rdfs:comment "Any amino sugar that is a monosaccharide in which one alcoholic hydroxy group is replaced by an amino group." ;
rdfs:subClassOf obo:CHEBI_28963 .
obo:CL_0002220 a rdfs:Class ;
rdfs:label "interstitial cell of pineal gland" ;
rdfs:comment "A cell located between the pinealocytes." ;
rdfs:subClassOf obo:CL_0000710 .
obo:IDO_0000528 a rdfs:Class ;
rdfs:label "pathogen"@en ;
rdfs:comment "A material entity with a pathogenic disposition."@en ;
rdfs:subClassOf obo:BFO_0000040 .
obo:UBERON_0003458 a rdfs:Class ;
rdfs:label "neck bone" ;
rdfs:comment "A bone that is part of a neck [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001474 .
obo:GO_0033048 a rdfs:Class ;
rdfs:label "negative regulation of mitotic sister chromatid segregation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." ;
rdfs:subClassOf obo:GO_0033046 , obo:GO_0033047 , obo:GO_0065007 .
obo:UBERON_0007098 a rdfs:Class ;
rdfs:label "mandibular neural crest" ;
rdfs:comment "Cranial neural crest that migrates into the mandibular arch." ;
rdfs:subClassOf obo:UBERON_0003099 .
obo:CL_0002603 a rdfs:Class ;
rdfs:label "astrocyte of the cerebellum" ;
rdfs:comment "An astrocyte of the cerebellum." ;
rdfs:subClassOf obo:CL_0000127 , obo:CL_2000005 .
obo:PATO_0045001 a rdfs:Class ;
rdfs:label "normal object quality" ;
rdfs:comment "A quality of an object that has a value that is normal or average." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:GO_0034762 a rdfs:Class ;
rdfs:label "regulation of transmembrane transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0051049 , obo:GO_0065007 .
obo:PHIPO_0001443 a rdfs:Class ;
rdfs:label "abnormal deoxynivalenol biosynthesis"@en ;
rdfs:comment "A single organism phenotype in which deoxynivalenol biosynthesis is abnormal." ;
rdfs:subClassOf obo:PHIPO_0001441 .
obo:CHEBI_81917 a rdfs:Class ;
rdfs:label "fenpropidin" ;
rdfs:comment "A racemate comprising equimolar amounts of (R)- and (S)-fenpropidin. A systemic fungicide, it is used for the control of foliar diseases in cereals and sugar beet." ;
rdfs:subClassOf obo:CHEBI_50860 , obo:CHEBI_60911 .
obo:GO_0060784 a rdfs:Class ;
rdfs:label "regulation of cell proliferation involved in tissue homeostasis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue." ;
rdfs:subClassOf obo:GO_0042127 .
obo:GO_0001832 a rdfs:Class ;
rdfs:label "blastocyst growth" ;
rdfs:comment "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation." ;
rdfs:subClassOf obo:GO_0040007 , obo:GO_0048589 .
obo:PHIPO_0000818 a rdfs:Class ;
rdfs:label "sensitive to salicylhydroxamic acid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to salicylhydroxamic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CL_0000241 a rdfs:Class ;
rdfs:label "stratified cuboidal epithelial cell" ;
rdfs:comment "A stratified epithelial cell that is part of cuboidal epithelium, characterized by multiple layers of cuboidal cells forming the apical layer. This provides a protective lining for ducts in large glands, such as sweat glands." ;
rdfs:subClassOf obo:CL_0000075 , obo:CL_0000079 .
obo:CHEBI_50685 a rdfs:Class ;
rdfs:label "antitrichomonal drug" ;
rdfs:comment "A drug used to treat trichomonas infections." ;
rdfs:subClassOf obo:CHEBI_35820 .
obo:CHEBI_33561 a rdfs:Class ;
rdfs:label "d-block element atom" ;
rdfs:subClassOf obo:CHEBI_27081 .
obo:CHEBI_78433 a rdfs:Class ;
rdfs:label "refrigerant" ;
rdfs:comment "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:PHIPO_0000082 a rdfs:Class ;
rdfs:label "abnormal number of asexual spores"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of asexual spores is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000078 .
obo:UBERON_0004469 a rdfs:Class ;
rdfs:label "musculature of back" ;
rdfs:comment "Any collection of muscles that is part of a back [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001015 .
obo:CHEBI_51737 a rdfs:Class ;
rdfs:label "alpha,beta-unsaturated carboxylic ester" ;
rdfs:comment "A carboxylic ester of general formula R1R2C=CR3‒C(=O)OR4 (R4 ≠ H) or R1C≡C‒C(=O)OR2 (R2 ≠ H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_33308 .
obo:UBERON_0001416 a rdfs:Class ;
rdfs:label "skin of abdomen" ;
rdfs:comment "A zone of skin that is part of an abdomen [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0003836 .
obo:CL_0007001 a rdfs:Class ;
rdfs:label "skeletogenic cell" ;
rdfs:comment "Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized)." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0045654 a rdfs:Class ;
rdfs:label "positive regulation of megakaryocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation." ;
rdfs:subClassOf obo:GO_0045639 , obo:GO_0045652 , obo:GO_0065007 .
obo:UBERON_0000483 a rdfs:Class ;
rdfs:label "epithelium" ;
rdfs:comment "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:UBERON_0005343 a rdfs:Class ;
rdfs:label "cortical plate" ;
rdfs:comment "The outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers[MP]." ;
rdfs:subClassOf obo:UBERON_0014950 .
obo:CHEBI_131609 a rdfs:Class ;
rdfs:label "pneumocandin B0" ;
rdfs:comment "An echinocandin initially isolated as a very minor bioactive fermentation product of Glarea lozoyensis (originally known as Zalerion arboricola). Subsequent random mutagenesis work and optimisation of the fermentation medium permitted the industrial production of pneumocandin B0, which is used as the starting point for the synthesis of the antifungal drug caspofungin." ;
rdfs:subClassOf obo:CHEBI_24613 , obo:CHEBI_57248 .
obo:GO_0007015 a rdfs:Class ;
rdfs:label "actin filament organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0097435 .
obo:GO_0051145 a rdfs:Class ;
rdfs:label "smooth muscle cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0042692 .
obo:GO_0021708 a rdfs:Class ;
rdfs:label "Lugaro cell differentiation" ;
rdfs:comment "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." ;
rdfs:subClassOf obo:GO_0021533 , obo:GO_0021953 , obo:GO_0030154 , obo:GO_0097154 .
obo:PHIPO_0000199 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host protein protein interaction" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." .
obo:GO_0061572 a rdfs:Class ;
rdfs:label "actin filament bundle organization" ;
rdfs:comment "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle." ;
rdfs:subClassOf obo:GO_0007015 , obo:GO_0016043 .
obo:GO_1904177 a rdfs:Class ;
rdfs:label "regulation of adipose tissue development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of adipose tissue development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:CHEBI_10022 a rdfs:Class ;
rdfs:label "deoxynivalenol" ;
rdfs:comment "A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination." ;
rdfs:subClassOf obo:CHEBI_15734 , obo:CHEBI_2468 , obo:CHEBI_27136 , obo:CHEBI_3992 , obo:CHEBI_51689 , obo:CHEBI_55517 .
obo:PHIPO_0000226 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction secondary metabolite biosynthetic process phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." .
obo:UBERON_0004148 a rdfs:Class ;
rdfs:label "cardiac vein" ;
rdfs:comment "Vein of heart that drains the myocardium." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0003498 , obo:UBERON_0005194 , obo:UBERON_0013140 .
obo:UBERON_0024090 a rdfs:Class ;
rdfs:label "chemoarchitectural part of brain" ;
rdfs:comment "Regional part of an anatomical region that is revealed by the use of a stain that reveals chemoarchitecture." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:CHEBI_39159 a rdfs:Class ;
rdfs:label "(S)-trichostatic acid" ;
rdfs:subClassOf obo:CHEBI_39157 .
obo:GO_1904408 a rdfs:Class ;
rdfs:label "melatonin binding" ;
rdfs:comment "Binding to melatonin." ;
rdfs:subClassOf obo:GO_0005488 .
obo:UBERON_0003469 a rdfs:Class ;
rdfs:label "respiratory system artery" ;
rdfs:comment "An artery that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0003643 .
obo:GO_0048145 a rdfs:Class ;
rdfs:label "regulation of fibroblast proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:PHIPO_0000858 a rdfs:Class ;
rdfs:label "sensitive to bifonazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to bifonazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_46733 a rdfs:Class ;
rdfs:label "oxabicycloalkane" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38104 .
obo:CHEBI_87835 a rdfs:Class ;
rdfs:label "framycetin(6+)" ;
rdfs:comment "An organic cation obtained by protonation of the six amino groups of framycetin; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:UBERON_0012466 a rdfs:Class ;
rdfs:label "extraembryonic cavity" ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:CL_4310127 a rdfs:Class ;
rdfs:label "VIP GABA VIP GABAergic interneuron (Primate)" ;
rdfs:comment "A VIP GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:VIP GABA." ;
rdfs:subClassOf obo:CL_4023016 .
obo:UBERON_0010011 a rdfs:Class ;
rdfs:label "collection of basal ganglia" ;
rdfs:comment "Subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum." ;
rdfs:subClassOf obo:UBERON_0010009 .
obo:GO_0021510 a rdfs:Class ;
rdfs:label "spinal cord development" ;
rdfs:comment "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_33497 a rdfs:Class ;
rdfs:label "transition element molecular entity" ;
rdfs:comment "A molecular entity containing one or more atoms of a transition element." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:UBERON_0019269 a rdfs:Class ;
rdfs:label "gray matter of diencephalon" ;
rdfs:subClassOf obo:UBERON_0002020 , obo:UBERON_0019264 .
obo:GO_0030885 a rdfs:Class ;
rdfs:label "regulation of myeloid dendritic cell activation" ;
rdfs:comment "Any process that modulates the frequency or rate of myeloid dendritic cell activation." ;
rdfs:subClassOf obo:GO_0002694 , obo:GO_0065007 .
obo:GO_0005634 a rdfs:Class ;
rdfs:label "nucleus" ;
rdfs:comment "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." ;
rdfs:subClassOf obo:GO_0043231 .
obo:UBERON_0003909 a rdfs:Class ;
rdfs:label "sinusoid" ;
rdfs:comment "Small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]." ;
rdfs:subClassOf obo:UBERON_2005260 .
obo:GO_0045214 a rdfs:Class ;
rdfs:label "sarcomere organization" ;
rdfs:comment "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0031032 .
obo:GO_2000068 a rdfs:Class ;
rdfs:label "regulation of defense response to insect" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of defense response to insect." ;
rdfs:subClassOf obo:GO_0002831 , obo:GO_0031347 , obo:GO_0032101 , obo:GO_0065007 .
obo:UBERON_0003075 a rdfs:Class ;
rdfs:label "neural plate" ;
rdfs:comment "A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]." ;
rdfs:subClassOf obo:UBERON_0005291 , obo:UBERON_0010371 , obo:UBERON_0016879 .
obo:UBERON_0007842 a rdfs:Class ;
rdfs:label "membrane bone" ;
rdfs:comment "Bone element that arises as a result of intramembranous ossification." ;
rdfs:subClassOf obo:UBERON_0001474 .
obo:GO_0061309 a rdfs:Class ;
rdfs:label "cardiac neural crest cell development involved in outflow tract morphogenesis" ;
rdfs:comment "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract." ;
rdfs:subClassOf obo:GO_0014032 , obo:GO_0061308 .
obo:CHEBI_86324 a rdfs:Class ;
rdfs:label "quinolone antibiotic" ;
rdfs:comment "An organonitrogen heterocyclic antibiotic whose structure contains a quinolone or quinolone-related skeleton." ;
rdfs:subClassOf obo:CHEBI_25558 .
obo:UBERON_8480002 a rdfs:Class ;
rdfs:label "thoracic aorta smooth muscle tissue" ;
rdfs:comment "A portion of smooth muscle tissue that is part of the thoracic aorta." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004178 .
obo:UBERON_0035539 a rdfs:Class ;
rdfs:label "esophageal artery" ;
rdfs:comment "Any of several arteries that arise from the aorta and supply blood to the esophagus." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0004573 .
obo:CHEBI_50320 a rdfs:Class ;
rdfs:label "nucleoside residue" ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:GO_0098959 a rdfs:Class ;
rdfs:label "retrograde dendritic transport of mitochondrion" ;
rdfs:comment "The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0098939 .
obo:UBERON_0002091 a rdfs:Class ;
rdfs:label "appendicular skeleton" ;
rdfs:comment "Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:CHEBI_17514 a rdfs:Class ;
rdfs:label "cyanide" ;
rdfs:comment "A pseudohalide anion that is the conjugate base of hydrogen cyanide." ;
rdfs:subClassOf obo:CHEBI_36828 .
obo:GO_0060409 a rdfs:Class ;
rdfs:label "positive regulation of acetylcholine metabolic process" ;
rdfs:comment "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ;
rdfs:subClassOf obo:GO_0033240 , obo:GO_0060408 , obo:GO_0065007 .
obo:GO_0016310 a rdfs:Class ;
rdfs:label "phosphorylation" ;
rdfs:comment "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." ;
rdfs:subClassOf obo:GO_0006796 .
obo:UBERON_0007475 a rdfs:Class ;
rdfs:label "matrix-based tissue" ;
rdfs:comment "A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:GO_0060094 a rdfs:Class ;
rdfs:label "positive regulation of synaptic transmission, glycinergic" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." ;
rdfs:subClassOf obo:GO_0050806 , obo:GO_0060092 , obo:GO_0065007 .
obo:CHEBI_24533 a rdfs:Class ;
rdfs:label "heterodetic cyclic peptide" ;
rdfs:comment "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." ;
rdfs:subClassOf obo:CHEBI_23449 .
obo:PHIPO_0000480 a rdfs:Class ;
rdfs:label "presence of pathogen-associated host lesions"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion is present." ;
rdfs:subClassOf obo:PHIPO_0000445 .
obo:GO_0045089 a rdfs:Class ;
rdfs:label "positive regulation of innate immune response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." ;
rdfs:subClassOf obo:GO_0002833 , obo:GO_0031349 , obo:GO_0032103 , obo:GO_0045088 , obo:GO_0050778 , obo:GO_0065007 .
obo:PHIPO_0000605 a rdfs:Class ;
rdfs:label "resistance to 4-aminosalicylic acid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to 4-aminosalicylic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0008406 a rdfs:Class ;
rdfs:label "gonad development" ;
rdfs:comment "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048608 , obo:GO_0048856 .
obo:UBERON_0000487 a rdfs:Class ;
rdfs:label "simple squamous epithelium" ;
rdfs:comment "Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0006914 .
obo:UBERON_0003928 a rdfs:Class ;
rdfs:label "digestive system duct" ;
rdfs:comment "A duct that is part of a digestive system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000058 .
obo:PHIPO_0001321 a rdfs:Class ;
rdfs:label "normal growth on flumorph"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to flumorph (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0099012 a rdfs:Class ;
rdfs:label "neuronal dense core vesicle membrane" ;
rdfs:comment "The lipid bilayer surrounding a neuronal dense core vesicle." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0032127 .
obo:PHIPO_0001356 a rdfs:Class ;
rdfs:label "resistance to fluopyram" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fluopyram. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_0000556 a rdfs:Class ;
rdfs:label "megakaryocyte" ;
rdfs:comment "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." ;
rdfs:subClassOf obo:CL_0000763 .
obo:GO_0120007 a rdfs:Class ;
rdfs:label "negative regulation of glutamatergic neuron differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation." ;
rdfs:subClassOf obo:GO_0045665 , obo:GO_0065007 , obo:GO_0120006 .
obo:GO_0048562 a rdfs:Class ;
rdfs:label "embryonic organ morphogenesis" ;
rdfs:comment "Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ;
rdfs:subClassOf obo:GO_0009887 , obo:GO_0048598 .
obo:PHIPO_0001045 a rdfs:Class ;
rdfs:label "decreased level of pathogen produced toxin within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen produced toxin usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001043 .
obo:GO_1902722 a rdfs:Class ;
rdfs:label "positive regulation of prolactin secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of prolactin secretion." ;
rdfs:subClassOf obo:GO_0050714 , obo:GO_0065007 , obo:GO_0090277 .
obo:UBERON_0003512 a rdfs:Class ;
rdfs:label "lung blood vessel" ;
rdfs:comment "A blood vessel that is part of a lung [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003504 , obo:UBERON_0003834 .
obo:GO_0062125 a rdfs:Class ;
rdfs:label "regulation of mitochondrial gene expression" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0065007 .
obo:CHEBI_29687 a rdfs:Class ;
rdfs:label "teicoplanin" ;
rdfs:comment "A complex mixture of related natural products isolated from the fermentation broth of a strain of Actinoplanes teichomyceticus comprising five major components (teicoplanin A2-1 through A2-5), a hydrolysis component (teicoplanin A3-1), and four minor components (teicoplanin RS-1 through RS-4). An antibiotic with a similar spectrum of activity to vancomycin, it is used to treat serious Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis." ;
rdfs:subClassOf obo:CHEBI_50860 , obo:CHEBI_60004 .
obo:GO_0098878 a rdfs:Class ;
rdfs:label "neurotransmitter receptor complex" ;
rdfs:comment "Any protein complex that is capable of functioning as a neurotransmitter receptor." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0098802 .
obo:GO_0002706 a rdfs:Class ;
rdfs:label "regulation of lymphocyte mediated immunity" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity." ;
rdfs:subClassOf obo:GO_0002703 , obo:GO_0065007 .
obo:CHEBI_417636 a rdfs:Class ;
rdfs:label "4-{((R)-2-Carboxy-3-methoxymethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-7-ylcarbamoyl)-[(Z)-methoxyimino]-methyl}-thiazol-2-yl-ammonium" ;
rdfs:subClassOf obo:CHEBI_23066 , obo:CHEBI_33575 .
obo:UBERON_0035965 a rdfs:Class ;
rdfs:label "wall of blood vessel" ;
rdfs:subClassOf obo:UBERON_0000060 .
obo:CHEBI_16796 a rdfs:Class .
obo:GO_0003012 a rdfs:Class ;
rdfs:label "muscle system process" ;
rdfs:comment "An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." ;
rdfs:subClassOf obo:GO_0003008 .
obo:CHEBI_50908 a rdfs:Class ;
rdfs:label "hepatotoxic agent" ;
rdfs:comment "A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:GO_0010935 a rdfs:Class ;
rdfs:label "regulation of macrophage cytokine production" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0002718 , obo:GO_0065007 .
obo:GO_1903046 a rdfs:Class ;
rdfs:label "meiotic cell cycle process" ;
rdfs:comment "A process that is part of the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0022402 , obo:GO_0022414 .
obo:GO_0022012 a rdfs:Class ;
rdfs:label "subpallium cell proliferation in forebrain" ;
rdfs:comment "The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population." ;
rdfs:subClassOf obo:GO_0021846 .
obo:GO_1905821 a rdfs:Class ;
rdfs:label "positive regulation of chromosome condensation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chromosome condensation." ;
rdfs:subClassOf obo:GO_0060623 , obo:GO_0065007 , obo:GO_2001252 .
obo:PHIPO_0000930 a rdfs:Class ;
rdfs:label "cellular process phenotype"@en ;
rdfs:comment "A phenotype that affects a cellular process." ;
rdfs:subClassOf obo:PHIPO_0000034 .
obo:CHEBI_471744 a rdfs:Class ;
rdfs:label "imipenem" ;
rdfs:comment "A broad-spectrum, intravenous β-lactam antibiotic of the carbapenem subgroup." ;
rdfs:subClassOf obo:CHEBI_46633 , obo:CHEBI_88225 .
obo:GO_0032227 a rdfs:Class ;
rdfs:label "negative regulation of synaptic transmission, dopaminergic" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." ;
rdfs:subClassOf obo:GO_0032225 , obo:GO_0050805 , obo:GO_0065007 .
obo:GO_0002367 a rdfs:Class ;
rdfs:label "cytokine production involved in immune response" ;
rdfs:comment "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0001816 , obo:GO_0002440 .
obo:GO_0097534 a rdfs:Class ;
rdfs:label "lymphoid lineage cell migration" ;
rdfs:comment "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage." ;
rdfs:subClassOf obo:GO_0016477 .
obo:UBERON_0000106 a rdfs:Class ;
rdfs:label "zygote stage" ;
rdfs:comment "A stage at which the organism is a single cell produced by means of sexual reproduction." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:RO_0002223 a rdf:Property ;
rdfs:label "starts"@en ;
rdfs:comment "inverse of starts with" ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000050 .
obo:GO_0040019 a rdfs:Class ;
rdfs:label "positive regulation of embryonic development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of embryonic development." ;
rdfs:subClassOf obo:GO_0045995 , obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0097367 a rdfs:Class ;
rdfs:label "carbohydrate derivative binding" ;
rdfs:comment "Binding to a carbohydrate derivative." ;
rdfs:subClassOf obo:GO_0005488 .
obo:GO_2000114 a rdfs:Class ;
rdfs:label "regulation of establishment of cell polarity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of establishment of cell polarity." ;
rdfs:subClassOf obo:GO_0032878 , obo:GO_0065007 .
obo:GO_0003161 a rdfs:Class ;
rdfs:label "cardiac conduction system development" ;
rdfs:comment "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat." ;
rdfs:subClassOf obo:GO_0048738 , obo:GO_0048856 .
obo:PHIPO_0001010 a rdfs:Class ;
rdfs:label "normal vesicle-mediated transport during vegetative growth"@en ;
rdfs:comment "A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001011 .
obo:NCBITaxon_3701028 a rdfs:Class ;
rdfs:label "Altocrustacea" ;
rdfs:subClassOf obo:NCBITaxon_197562 .
obo:UBERON_0034705 a rdfs:Class ;
rdfs:label "developing neuroepithelium" ;
rdfs:comment "An embryonic or larval epithelium that is committed to form part of the nervous system." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:CL_4301615 a rdfs:Class ;
rdfs:label "olfactory ensheathing cell (Mmus)" ;
rdfs:comment "A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Npy (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1185 OEC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0011028 .
obo:PHIPO_0000610 a rdfs:Class ;
rdfs:label "resistance to linezolid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to linezolid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0031965 a rdfs:Class ;
rdfs:label "nuclear membrane" ;
rdfs:comment "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031090 .
obo:UBERON_0000154 a rdfs:Class ;
rdfs:label "posterior region of body" ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:GO_0098840 a rdfs:Class ;
rdfs:label "protein transport along microtubule" ;
rdfs:comment "The directed movement of a protein along a microtubule, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0006886 , obo:GO_0010970 , obo:GO_0046907 , obo:GO_0099118 .
obo:GO_0016106 a rdfs:Class ;
rdfs:label "sesquiterpenoid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units." ;
rdfs:subClassOf obo:GO_0006714 , obo:GO_0016114 .
obo:GO_1900193 a rdfs:Class ;
rdfs:label "regulation of oocyte maturation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of oocyte maturation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903429 , obo:GO_2000241 .
obo:PR_P22646 a rdfs:Class ;
rdfs:label "T-cell surface glycoprotein CD3 epsilon chain (mouse)" ;
rdfs:comment "A CD3 epsilon that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001020 , obo:PR_000029032 .
obo:GO_0006865 a rdfs:Class ;
rdfs:label "amino acid transport" ;
rdfs:comment "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 .
obo:CL_0008055 a rdfs:Class ;
rdfs:label "respiratory tract secretory epithelial cell" ;
rdfs:comment "A secretory epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin." ;
rdfs:subClassOf obo:CL_0002368 , obo:CL_1100001 .
obo:UBERON_0025736 a rdfs:Class ;
rdfs:label "chemoarchitectural part of striatum" ;
rdfs:subClassOf obo:UBERON_0024090 .
obo:GO_1905607 a rdfs:Class ;
rdfs:label "negative regulation of presynapse assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly." ;
rdfs:subClassOf obo:GO_0051964 , obo:GO_0065007 , obo:GO_1905606 .
obo:CHEBI_52017 a rdfs:Class ;
rdfs:label "dicloxacillin(1-)" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:CL_1000414 a rdfs:Class ;
rdfs:label "endothelial cell of venule" ;
rdfs:comment "An endothelial cell that is part of the venule." ;
rdfs:subClassOf obo:CL_0000071 , obo:CL_0002139 .
obo:GO_0099550 a rdfs:Class ;
rdfs:label "trans-synaptic signaling, modulating synaptic transmission" ;
rdfs:comment "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0099537 .
obo:CHEBI_76971 a rdfs:Class ;
rdfs:label "Escherichia coli metabolite" ;
rdfs:comment "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." ;
rdfs:subClassOf obo:CHEBI_76969 .
obo:GO_0050866 a rdfs:Class ;
rdfs:label "negative regulation of cell activation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0050865 , obo:GO_0051241 , obo:GO_0065007 .
obo:CHEBI_73678 a rdfs:Class ;
rdfs:label "tobramycin(5+)" ;
rdfs:comment "An organic cation obtained by protonation of the five amino groups of tobramycin." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:PHIPO_0000376 a rdfs:Class ;
rdfs:label "premature pathogen penetration structure formation when near host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the formation of pathogen specialized penetration structure begins sooner than normal." ;
rdfs:subClassOf obo:PHIPO_0000369 .
obo:CHEBI_50696 a rdfs:Class ;
rdfs:label "EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor" ;
rdfs:comment "An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of peptidoglycan glycosyltransferase (EC 2.4.1.129)." ;
rdfs:subClassOf obo:CHEBI_76789 .
obo:UBERON_0002539 a rdfs:Class ;
rdfs:label "pharyngeal arch" ;
rdfs:comment "One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0010188 , obo:UBERON_0010314 .
obo:CL_1000410 a rdfs:Class ;
rdfs:label "myocyte of atrioventricular node" ;
rdfs:comment "A muscle cell that is part of the atrioventricular node." ;
rdfs:subClassOf obo:CL_0000187 , obo:CL_0002072 , obo:CL_0008009 , obo:CL_2000022 .
obo:CHEBI_45599 a rdfs:Class ;
rdfs:label "dodecyl hydrogen sulfate" ;
rdfs:subClassOf obo:CHEBI_29281 .
obo:GO_1901706 a rdfs:Class ;
rdfs:label "mesenchymal cell differentiation involved in bone development" ;
rdfs:comment "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state." ;
rdfs:subClassOf obo:GO_0048762 .
obo:GO_1904268 a rdfs:Class ;
rdfs:label "positive regulation of Schwann cell chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis." ;
rdfs:subClassOf obo:GO_0050921 , obo:GO_0065007 , obo:GO_1900149 , obo:GO_1904266 .
obo:GO_0048644 a rdfs:Class ;
rdfs:label "muscle organ morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of muscle are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:GO_0001894 a rdfs:Class ;
rdfs:label "tissue homeostasis" ;
rdfs:comment "A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function." ;
rdfs:subClassOf obo:GO_0060249 .
obo:GO_0043649 a rdfs:Class ;
rdfs:label "dicarboxylic acid catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0043648 , obo:GO_0046395 .
obo:PHIPO_0000370 a rdfs:Class ;
rdfs:label "obsolete pathogen penetration structure absent when near host" ;
rdfs:comment "A pathogen growth with host phenotype in which the pathogen specialized host penetration structure is absent." .
obo:PHIPO_0000164 a rdfs:Class ;
rdfs:label "pathogen host interaction binding phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype that affects the binding of a gene product to another substance. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000347 .
obo:GO_1905454 a rdfs:Class ;
rdfs:label "negative regulation of myeloid progenitor cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901533 , obo:GO_1905453 .
obo:UBERON_0001575 a rdfs:Class ;
rdfs:label "extrinsic muscle of tongue" ;
rdfs:comment "A muscle organ that attaches the tongue to some other structure." ;
rdfs:subClassOf obo:UBERON_0000378 , obo:UBERON_0014892 .
obo:PHIPO_0001273 a rdfs:Class ;
rdfs:label "abnormal host morphology during phagocytosis of pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype where the morphology of the host cell is irregular due to the phagocytosis (engulfment and ingestion) of the pathogen (GO:0006911)." ;
rdfs:subClassOf obo:PHIPO_0001006 .
obo:UBERON_0000068 a rdfs:Class ;
rdfs:label "embryo stage" ;
rdfs:comment "A life cycle stage that starts with fertilization and ends with the fully formed embryo." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:UBERON_0009578 a rdfs:Class ;
rdfs:label "myelencephalon sulcus limitans" ;
rdfs:comment "A sulcus limitans of neural tube that is part of a future myelencephalon." ;
rdfs:subClassOf obo:UBERON_0005478 .
obo:GO_2000106 a rdfs:Class ;
rdfs:label "regulation of leukocyte apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of leukocyte apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:GO_0033603 a rdfs:Class ;
rdfs:label "positive regulation of dopamine secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine." ;
rdfs:subClassOf obo:GO_0014059 , obo:GO_0033605 , obo:GO_0065007 .
obo:GO_0140297 a rdfs:Class ;
rdfs:label "DNA-binding transcription factor binding" ;
rdfs:comment "Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription." ;
rdfs:subClassOf obo:GO_0008134 .
obo:GO_2001027 a rdfs:Class ;
rdfs:label "negative regulation of endothelial cell chemotaxis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis." ;
rdfs:subClassOf obo:GO_0010596 , obo:GO_0050922 , obo:GO_0065007 , obo:GO_2001026 .
obo:PHIPO_0001448 a rdfs:Class ;
rdfs:label "restored pathogenicity"@en ;
rdfs:comment "A phenotype where the ability of a pathogen to produce an infectious disease in another organism is restored (pathogenicity was present, then absent, and now present)." ;
rdfs:subClassOf obo:PHIPO_0000006 .
obo:UBERON_0005158 a rdfs:Class ;
rdfs:label "parenchyma of central nervous system" ;
rdfs:comment "The functional tissue of the central nervous system consisting of neurons and glial cells." ;
rdfs:subClassOf obo:UBERON_0000353 .
obo:PHIPO_0000645 a rdfs:Class ;
rdfs:label "resistance to ticarcillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ticarcillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:GO_0097177 a rdfs:Class ;
rdfs:label "mitochondrial ribosome binding" ;
rdfs:comment "Binding to a mitochondrial ribosome." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0043022 .
obo:PHIPO_0000530 a rdfs:Class ;
rdfs:label "resistance to triadimefon"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to triadimefon. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000659 a rdfs:Class ;
rdfs:label "resistance to gentamicin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to gentamicin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0019042 a rdfs:Class ;
rdfs:label "reproductive system mucosa" ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0005156 .
obo:GO_0016818 a rdfs:Class ;
rdfs:label "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides" ;
rdfs:comment "Catalysis of the hydrolysis of any acid anhydride which contains phosphorus." ;
rdfs:subClassOf obo:GO_0016817 .
obo:GO_0010842 a rdfs:Class ;
rdfs:label "retina layer formation" ;
rdfs:comment "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0002700 a rdfs:Class ;
rdfs:label "regulation of production of molecular mediator of immune response" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response." ;
rdfs:subClassOf obo:GO_0002697 , obo:GO_0010468 , obo:GO_0065007 .
obo:GO_1904036 a rdfs:Class ;
rdfs:label "negative regulation of epithelial cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0065007 , obo:GO_1904035 .
obo:GO_0090174 a rdfs:Class ;
rdfs:label "organelle membrane fusion" ;
rdfs:comment "The joining of two lipid bilayers to form a single organelle membrane." ;
rdfs:subClassOf obo:GO_0048284 , obo:GO_0061025 .
obo:GO_0034487 a rdfs:Class ;
rdfs:label "vacuolar amino acid transmembrane transport" ;
rdfs:comment "The process in which an amino acid is transported from one side of the vacuolar membrane to the other." ;
rdfs:subClassOf obo:GO_0003333 , obo:GO_0006810 .
obo:GO_0046666 a rdfs:Class ;
rdfs:label "retinal cell programmed cell death" ;
rdfs:comment "Programmed cell death that occurs in the developing retina." ;
rdfs:subClassOf obo:GO_0010623 .
obo:CHEBI_27780 a rdfs:Class ;
rdfs:label "detergent" ;
rdfs:comment "A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions." ;
rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_35195 .
obo:CHEBI_87209 a rdfs:Class ;
rdfs:label "virginiamycin" ;
rdfs:comment "A mixture of cyclic polypeptide streptogramin antibiotics produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. The two major components are virginiamycin M1 (also known as pristinamycin IIA) and virginiamycin S1. Virginiamycin has been widely used as a growth promotion agent in livestock and has been to have bacteriostatic activity against Gram-positive organisms such as staphylococci and streptococci." ;
rdfs:subClassOf obo:CHEBI_50860 , obo:CHEBI_60004 .
obo:GO_0010561 a rdfs:Class ;
rdfs:label "negative regulation of glycoprotein biosynthetic process" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ;
rdfs:subClassOf obo:GO_0010558 , obo:GO_0010559 , obo:GO_0065007 , obo:GO_1903019 .
obo:GO_0009057 a rdfs:Class ;
rdfs:label "macromolecule catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0043170 .
obo:GO_0030336 a rdfs:Class ;
rdfs:label "negative regulation of cell migration" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 , obo:GO_2000146 .
obo:GO_0044217 a rdfs:Class ;
rdfs:label "other organism part" ;
rdfs:comment "Any constituent part of a secondary organism with which the first organism is interacting." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0001568 a rdfs:Class ;
rdfs:label "blood vessel development" ;
rdfs:comment "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood." ;
rdfs:subClassOf obo:GO_0048856 .
obo:PHIPO_0001062 a rdfs:Class ;
rdfs:label "increased RNA level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of RNA measured in a cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." ;
rdfs:subClassOf obo:PHIPO_0001036 , obo:PHIPO_0001060 .
obo:CL_1000443 a rdfs:Class ;
rdfs:label "ciliary muscle cell" ;
rdfs:comment "A smooth muscle cell that is part of the ciliary body." ;
rdfs:subClassOf obo:CL_0000192 .
obo:CHEBI_33266 a rdfs:Class ;
rdfs:label "diatomic nitrogen" ;
rdfs:subClassOf obo:CHEBI_33267 .
obo:GO_0051128 a rdfs:Class ;
rdfs:label "regulation of cellular component organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:CHEBI_2676 a rdfs:Class ;
rdfs:label "amoxicillin" ;
rdfs:comment "A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_88187 .
obo:CL_2000020 a rdfs:Class ;
rdfs:label "inner cell mass cell" ;
rdfs:comment "Any native cell that is part of a inner cell mass." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_0016114 a rdfs:Class ;
rdfs:label "terpenoid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure." ;
rdfs:subClassOf obo:GO_0006721 , obo:GO_0008299 .
obo:PHIPO_0001090 a rdfs:Class ;
rdfs:label "abolished protein secretion"@en ;
rdfs:comment "A single organism localization phenotype in which a protein is not exported via the secretory pathway." ;
rdfs:subClassOf obo:PHIPO_0000245 .
obo:UBERON_0002521 a rdfs:Class ;
rdfs:label "elastic tissue" ;
rdfs:comment "Connective tissue composed of elastic fibers." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:UBERON_0002390 a rdfs:Class ;
rdfs:label "hematopoietic system" ;
rdfs:comment "Anatomical system that is involved in the production of hematopoietic cells." ;
rdfs:subClassOf obo:UBERON_0000467 , obo:UBERON_0004120 .
obo:CL_0000187 a rdfs:Class ;
rdfs:label "muscle cell" ;
rdfs:comment "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." ;
rdfs:subClassOf obo:CL_0000183 , obo:CL_0000255 , obo:CL_0000393 .
obo:PATO_0000051 a rdfs:Class ;
rdfs:label "morphology" ;
rdfs:comment "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:GO_0140236 a rdfs:Class ;
rdfs:label "translation at presynapse" ;
rdfs:comment "Translation that occurs at the presynapse." ;
rdfs:subClassOf obo:GO_0006412 , obo:GO_0140241 .
obo:GO_0050000 a rdfs:Class ;
rdfs:label "chromosome localization" ;
rdfs:comment "Any process in which a chromosome is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051640 .
obo:GO_0051155 a rdfs:Class ;
rdfs:label "positive regulation of striated muscle cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051149 , obo:GO_0051153 , obo:GO_0065007 .
obo:CHEBI_75768 a rdfs:Class ;
rdfs:label "mammalian metabolite" ;
rdfs:comment "Any animal metabolite produced during a metabolic reaction in mammals." ;
rdfs:subClassOf obo:CHEBI_75767 .
obo:GO_0150146 a rdfs:Class ;
rdfs:label "cell junction disassembly" ;
rdfs:comment "The disaggregation of a cell junction into its constituent components." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0034330 .
obo:GO_0021897 a rdfs:Class ;
rdfs:label "forebrain astrocyte development" ;
rdfs:comment "The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function." ;
rdfs:subClassOf obo:GO_0014002 , obo:GO_0048468 .
obo:UBERON_0016514 a rdfs:Class ;
rdfs:label "cavity of left ventricle" ;
rdfs:comment "Luminal space of the left ventricle of the heart." ;
rdfs:subClassOf obo:UBERON_0002553 , obo:UBERON_0035763 .
obo:GO_1903292 a rdfs:Class ;
rdfs:label "protein localization to Golgi membrane" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0034067 , obo:GO_0072657 .
obo:GO_2000497 a rdfs:Class ;
rdfs:label "positive regulation of cell proliferation involved in compound eye morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0065007 , obo:GO_2000495 .
obo:PHIPO_0000619 a rdfs:Class ;
rdfs:label "resistance to farnesol"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to farnesol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0006563 a rdfs:Class ;
rdfs:label "tunica media of pulmonary trunk" ;
rdfs:comment "Tunica media of artery which is continuous with the myocardium of right ventricle.[FMA]." ;
rdfs:subClassOf obo:UBERON_0002522 , obo:UBERON_0007239 .
obo:PHIPO_0001225 a rdfs:Class ;
rdfs:label "chitin hydrolysis present"@en ;
rdfs:comment "A single species metabolic cellular process phenotype, in which a pathogen effector does not prevent the hydrolysis of chitin by chitinases." ;
rdfs:subClassOf obo:PHIPO_0001147 .
obo:GO_0072537 a rdfs:Class ;
rdfs:label "fibroblast activation" ;
rdfs:comment "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." ;
rdfs:subClassOf obo:GO_0001775 .
obo:GO_1900194 a rdfs:Class ;
rdfs:label "negative regulation of oocyte maturation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900193 , obo:GO_1903430 , obo:GO_2000242 .
obo:PHIPO_0000467 a rdfs:Class ;
rdfs:label "presence of effector-independent host hypersensitive response"@en ;
rdfs:comment "A single species phenotype where the immune system process of host tissue hypersensitive response is present in a pathogen effector-independant manner. (i.e. an alteration within the host is responsible for the activation of the hypersensitive response in the absence of a pathogen)." ;
rdfs:subClassOf obo:PHIPO_0000446 , obo:PHIPO_0000929 .
obo:GO_0099140 a rdfs:Class ;
rdfs:label "presynaptic actin cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0030036 , obo:GO_0099187 .
obo:GO_0061337 a rdfs:Class ;
rdfs:label "cardiac conduction" ;
rdfs:comment "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles." ;
rdfs:subClassOf obo:GO_0008016 .
obo:GO_0014742 a rdfs:Class ;
rdfs:label "positive regulation of muscle hypertrophy" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy." ;
rdfs:subClassOf obo:GO_0014743 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0098926 a rdfs:Class ;
rdfs:label "postsynaptic signal transduction" ;
rdfs:comment "Signal transduction in which the initial step occurs in a postsynapse." ;
rdfs:subClassOf obo:GO_0007165 .
obo:GO_0003008 a rdfs:Class ;
rdfs:label "system process" ;
rdfs:comment "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0051784 a rdfs:Class ;
rdfs:label "negative regulation of nuclear division" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0051783 , obo:GO_0065007 .
obo:GO_0021543 a rdfs:Class ;
rdfs:label "pallium development" ;
rdfs:comment "The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_33431 a rdfs:Class ;
rdfs:label "elemental chlorine" ;
rdfs:subClassOf obo:CHEBI_23117 , obo:CHEBI_33434 .
obo:CL_0008007 a rdfs:Class ;
rdfs:label "visceral muscle cell"@en ;
rdfs:comment "A muscle cell that is part of some visceral muscle." ;
rdfs:subClassOf obo:CL_0000187 .
obo:GO_2000510 a rdfs:Class ;
rdfs:label "positive regulation of dendritic cell chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis." ;
rdfs:subClassOf obo:GO_0002690 , obo:GO_0065007 , obo:GO_0071677 , obo:GO_2000508 .
obo:GO_0099080 a rdfs:Class ;
rdfs:label "supramolecular complex" ;
rdfs:comment "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CL_0000167 a rdfs:Class ;
rdfs:label "peptide hormone secreting cell" ;
rdfs:comment "Any secretory cell that is capable of some peptide hormone secretion." ;
rdfs:subClassOf obo:CL_0000151 .
obo:UBERON_0000126 a rdfs:Class ;
rdfs:label "cranial nerve nucleus" ;
rdfs:comment "Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves." ;
rdfs:subClassOf obo:UBERON_0002308 .
obo:CHEBI_78616 a rdfs:Class ;
rdfs:label "carbohydrates and carbohydrate derivatives" ;
rdfs:comment "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:GO_0044127 a rdfs:Class ;
rdfs:label "regulation of development of symbiont in host" ;
rdfs:comment "Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction." ;
rdfs:subClassOf obo:GO_0044145 , obo:GO_0065007 .
obo:GO_0097474 a rdfs:Class ;
rdfs:label "retinal cone cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0051402 , obo:GO_1990009 .
obo:GO_0140243 a rdfs:Class ;
rdfs:label "regulation of translation at synapse" ;
rdfs:comment "Any process that regulates translation occurring at the synapse." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:GO_0070232 a rdfs:Class ;
rdfs:label "regulation of T cell apoptotic process" ;
rdfs:comment "Any process that modulates the occurrence or rate of T cell death by apoptotic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070228 .
obo:UBERON_0002286 a rdfs:Class ;
rdfs:label "third ventricle" ;
rdfs:comment "Part of the ventricular system of the brain, forming a single large cavity in the midline of the diencephalon; it is continuous with the lateral ventricles through the interventricular foramen and the fourth ventricle through the cerebral aqueduct. (Maryann Martone)." ;
rdfs:subClassOf obo:UBERON_0004086 .
obo:GO_0043297 a rdfs:Class ;
rdfs:label "apical junction assembly" ;
rdfs:comment "The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents." ;
rdfs:subClassOf obo:GO_0007043 , obo:GO_0022607 .
obo:UBERON_0006260 a rdfs:Class ;
rdfs:label "lingual swellings" ;
rdfs:comment "the collection consisting of the two lateral swellings and the medial swelling" ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0010188 .
obo:CL_0002549 a rdfs:Class ;
rdfs:label "fibroblast of choroid plexus" ;
rdfs:comment "A fibroblast that is part of the choroid plexus." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0002319 .
obo:GO_0043029 a rdfs:Class ;
rdfs:label "T cell homeostasis" ;
rdfs:comment "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." ;
rdfs:subClassOf obo:GO_0002260 , obo:GO_0048872 .
obo:GO_1905671 a rdfs:Class ;
rdfs:label "regulation of lysosome organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lysosome organization." ;
rdfs:subClassOf obo:GO_0044088 , obo:GO_0065007 .
obo:GO_0050776 a rdfs:Class ;
rdfs:label "regulation of immune response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0048583 , obo:GO_0065007 .
obo:CHEBI_50325 a rdfs:Class ;
rdfs:label "proteinogenic amino-acid side-chain group" ;
rdfs:comment "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid." ;
rdfs:subClassOf obo:CHEBI_33249 .
obo:CHEBI_22586 a rdfs:Class ;
rdfs:label "antioxidant" ;
rdfs:comment "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:PHIPO_0000763 a rdfs:Class ;
rdfs:label "sensitive to moxifloxacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to moxifloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CL_4310124 a rdfs:Class ;
rdfs:label "STR SST-RSPO2 GABA sst GABAergic interneuron (Primate)" ;
rdfs:comment "A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-RSPO2 GABA." ;
rdfs:subClassOf obo:CL_4023017 .
obo:GO_1905216 a rdfs:Class ;
rdfs:label "positive regulation of RNA binding" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of RNA binding." ;
rdfs:subClassOf obo:GO_0051099 , obo:GO_0065007 .
obo:UBERON_0000383 a rdfs:Class ;
rdfs:label "musculature of body" ;
rdfs:comment "The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:PHIPO_0000700 a rdfs:Class ;
rdfs:label "resistance to miconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to miconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_36914 a rdfs:Class ;
rdfs:label "inorganic ion" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_24870 .
obo:GO_0006414 a rdfs:Class ;
rdfs:label "translational elongation" ;
rdfs:comment "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." ;
rdfs:subClassOf obo:GO_0009059 .
obo:CHEBI_26469 a rdfs:Class ;
rdfs:label "quaternary nitrogen compound" ;
rdfs:comment "A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:GO_0043083 a rdfs:Class ;
rdfs:label "synaptic cleft" ;
rdfs:comment "The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released." ;
rdfs:subClassOf obo:GO_0110165 .
obo:UBERON_0000047 a rdfs:Class ;
rdfs:label "simple eye" ;
rdfs:comment "An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity." ;
rdfs:subClassOf obo:UBERON_0000970 .
obo:GO_0021799 a rdfs:Class ;
rdfs:label "cerebral cortex radially oriented cell migration" ;
rdfs:comment "The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain." ;
rdfs:subClassOf obo:GO_0021795 .
obo:GO_0032966 a rdfs:Class ;
rdfs:label "negative regulation of collagen biosynthetic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0010713 , obo:GO_0032965 , obo:GO_0065007 .
obo:PR_P61168 a rdfs:Class ;
rdfs:label "D(2) dopamine receptor (mouse)" ;
rdfs:comment "A D(2) dopamine receptor that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001177 , obo:PR_000029032 .
obo:GO_0015849 a rdfs:Class ;
rdfs:label "organic acid transport" ;
rdfs:comment "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 .
obo:PHIPO_0001002 a rdfs:Class ;
rdfs:label "host morphology phenotype during pathogen invasion"@en ;
rdfs:comment "A pathogen host interaction phenotype which affects the host morphology during pathogen invasion. This relates to the pathogen colonization of the body, tissues, or cells of the host organism" ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:GO_1900182 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to nucleus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900180 , obo:GO_1903829 .
obo:CHEBI_76834 a rdfs:Class ;
rdfs:label "EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor" ;
rdfs:comment "An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*)." ;
rdfs:subClassOf obo:CHEBI_71300 .
obo:PR_000002065 a rdfs:Class ;
rdfs:label "mast/stem cell growth factor receptor" ;
rdfs:comment "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001810 .
obo:GO_1903531 a rdfs:Class ;
rdfs:label "negative regulation of secretion by cell" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0051048 , obo:GO_0065007 , obo:GO_1903530 .
obo:PHIPO_0000684 a rdfs:Class ;
rdfs:label "resistance to minocycline"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to minocycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0051968 a rdfs:Class ;
rdfs:label "positive regulation of synaptic transmission, glutamatergic" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." ;
rdfs:subClassOf obo:GO_0050806 , obo:GO_0051966 , obo:GO_0065007 .
obo:PHIPO_0001421 a rdfs:Class ;
rdfs:label "sensitive to flutolanil" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to flutolanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0045780 a rdfs:Class ;
rdfs:label "positive regulation of bone resorption" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of bone resorption." ;
rdfs:subClassOf obo:GO_0045124 , obo:GO_0051240 , obo:GO_0065007 .
obo:CHEBI_63161 a rdfs:Class ;
rdfs:label "glycosyl compound" ;
rdfs:comment "A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity." ;
rdfs:subClassOf obo:CHEBI_63299 .
obo:CHEBI_76740 a rdfs:Class ;
rdfs:label "EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:PHIPO_0000566 a rdfs:Class ;
rdfs:label "resistance to tridemorph"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tridemorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0001764 a rdfs:Class ;
rdfs:label "neuron migration" ;
rdfs:comment "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." ;
rdfs:subClassOf obo:GO_0016477 .
obo:NCBITaxon_39107 a rdfs:Class ;
rdfs:label "Murinae" ;
rdfs:subClassOf obo:NCBITaxon_10066 .
obo:GO_0009786 a rdfs:Class ;
rdfs:label "regulation of asymmetric cell division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of asymmetric cell division." ;
rdfs:subClassOf obo:GO_0051302 , obo:GO_0065007 .
obo:GO_0048308 a rdfs:Class ;
rdfs:label "organelle inheritance" ;
rdfs:comment "The partitioning of organelles between daughter cells at cell division." ;
rdfs:subClassOf obo:GO_0006996 .
obo:UBERON_0009571 a rdfs:Class ;
rdfs:label "ventral midline" ;
rdfs:comment "In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:CHEBI_36336 a rdfs:Class ;
rdfs:label "naphthalenesulfonic acid" ;
rdfs:subClassOf obo:CHEBI_25477 , obo:CHEBI_33555 .
obo:CL_4052015 a rdfs:Class ;
rdfs:label "endocrine gland capillary endothelial cell" ;
rdfs:comment "Any capillary endothelial cell that is part of an endocrine gland." ;
rdfs:subClassOf obo:CL_0002144 .
obo:GO_0098631 a rdfs:Class ;
rdfs:label "cell adhesion mediator activity" ;
rdfs:comment "The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0050839 .
obo:CHEBI_23066 a rdfs:Class ;
rdfs:label "cephalosporin" ;
rdfs:comment "A class of β-lactam antibiotics differing from the penicillins in having a 6-membered, rather than a 5-membered, side ring. Although cephalosporins are among the most commonly used antibiotics in the treatment of routine infections, and their use is increasing over time, they can cause a range of hypersensitivity reactions, from mild, delayed-onset cutaneous reactions to life-threatening anaphylaxis in patients with immunoglobulin E (IgE)-mediated allergy." ;
rdfs:subClassOf obo:CHEBI_38311 .
obo:PHIPO_0001265 a rdfs:Class ;
rdfs:label "host hemorrhage with pathogen present"@en ;
rdfs:comment "A pathogen host interaction phenotype in which host bleeding occurs during pathogen infection (MP:0001914 hemorrhage)." ;
rdfs:subClassOf obo:PHIPO_0001264 .
obo:CL_0000988 a rdfs:Class ;
rdfs:label "hematopoietic cell" ;
rdfs:comment "A cell of a hematopoietic lineage." ;
rdfs:subClassOf obo:CL_0000000 .
obo:CHEBI_29369 a rdfs:Class ;
rdfs:label "peroxy group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:PHIPO_0000656 a rdfs:Class ;
rdfs:label "resistance to nicotinamide"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to nicotinamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_24628 a rdfs:Class ;
rdfs:label "imidazolidine-2,4-dione" ;
rdfs:comment "An imidazolidinone with oxo groups at position 2 and 4." ;
rdfs:subClassOf obo:CHEBI_55370 .
obo:CHEBI_83909 a rdfs:Class ;
rdfs:label "(1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol" ;
rdfs:comment "A member of the class of triazoles that is 4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol substituted at position 1 by a 2,4-dichlorophenyl group." ;
rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_35681 , obo:CHEBI_35727 , obo:CHEBI_78840 .
obo:GO_0098937 a rdfs:Class ;
rdfs:label "anterograde dendritic transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0098935 .
obo:GO_0030261 a rdfs:Class ;
rdfs:label "chromosome condensation" ;
rdfs:comment "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." ;
rdfs:subClassOf obo:GO_0051276 .
obo:UBERON_0010344 a rdfs:Class ;
rdfs:label "3rd arch mesenchyme from head mesenchyme" ;
rdfs:comment "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 3rd arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005690 , obo:UBERON_0010360 .
obo:CL_0002672 a rdfs:Class ;
rdfs:label "retinal progenitor cell" ;
rdfs:comment "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells." ;
rdfs:subClassOf obo:CL_0000048 , obo:CL_0000255 .
obo:GO_0045824 a rdfs:Class ;
rdfs:label "negative regulation of innate immune response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response." ;
rdfs:subClassOf obo:GO_0002832 , obo:GO_0031348 , obo:GO_0032102 , obo:GO_0045088 , obo:GO_0050777 , obo:GO_0065007 .
obo:GO_0021720 a rdfs:Class ;
rdfs:label "superior olivary nucleus formation" ;
rdfs:comment "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." ;
rdfs:subClassOf obo:GO_0048646 .
obo:BFO_0000004 a rdfs:Class ;
rdfs:label "independent continuant"@en ;
rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:GO_0007406 a rdfs:Class ;
rdfs:label "negative regulation of neuroblast proliferation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts." ;
rdfs:subClassOf obo:GO_0050768 , obo:GO_0065007 , obo:GO_1902692 , obo:GO_2000178 .
obo:PHIPO_0000237 a rdfs:Class ;
rdfs:label "protein localization phenotype"@en ;
rdfs:comment "A single organism phenotype that affects the localization of a protein in a cell." ;
rdfs:subClassOf obo:PHIPO_0000235 .
obo:GO_0099568 a rdfs:Class ;
rdfs:label "cytoplasmic region" ;
rdfs:comment "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." ;
rdfs:subClassOf obo:GO_0005737 .
obo:GO_0034654 a rdfs:Class ;
rdfs:label "nucleobase-containing compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0006139 , obo:GO_0009058 .
obo:PHIPO_0000877 a rdfs:Class ;
rdfs:label "sensitive to cefoxitin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefoxitin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0001074 a rdfs:Class ;
rdfs:label "pericardial cavity" ;
rdfs:comment "A potential space between the visceral and parietal layers of the pericardium." ;
rdfs:subClassOf obo:UBERON_0002323 , obo:UBERON_0002553 , obo:UBERON_0035809 .
obo:CHEBI_50010 a rdfs:Class ;
rdfs:label "4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonic acid" ;
rdfs:comment "An organosulfonic acid comprising stilbene having 4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino groups at the 4 and 4'-positions and sulfo groups at the 2- and 2'-positions." ;
rdfs:subClassOf obo:CHEBI_26588 , obo:CHEBI_33551 .
obo:PHIPO_0000027 a rdfs:Class ;
rdfs:label "normal pathogen growth after penetration of the barrier" ;
rdfs:comment "A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is normal (i.e indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000160 .
obo:GO_0021759 a rdfs:Class ;
rdfs:label "globus pallidus development" ;
rdfs:comment "The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048857 .
obo:CHEBI_24651 a rdfs:Class ;
rdfs:label "hydroxides" ;
rdfs:comment "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH−)." ;
rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_33608 , obo:CHEBI_37577 .
obo:GO_0009295 a rdfs:Class ;
rdfs:label "nucleoid" ;
rdfs:comment "The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_39144 a rdfs:Class ;
rdfs:label "Lewis base" ;
rdfs:comment "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." ;
rdfs:subClassOf obo:CHEBI_17891 , obo:CHEBI_22695 .
obo:CL_0002462 a rdfs:Class ;
rdfs:label "adipose dendritic cell" ;
rdfs:comment "A F4/80-negative dendritic cell located in adipose tissue." ;
rdfs:subClassOf obo:CL_0000766 , obo:CL_0000990 , obo:CL_0002320 .
obo:CHEBI_17087 a rdfs:Class ;
rdfs:label "ketone" ;
rdfs:comment "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." ;
rdfs:subClassOf obo:CHEBI_36586 .
obo:GO_2000382 a rdfs:Class ;
rdfs:label "positive regulation of mesoderm development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mesoderm development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_2000380 .
obo:GO_0021532 a rdfs:Class ;
rdfs:label "neural tube patterning" ;
rdfs:comment "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube." ;
rdfs:subClassOf obo:GO_0003002 .
obo:PHIPO_0000188 a rdfs:Class ;
rdfs:label "pathogen growth on host surface phenotype"@en ;
rdfs:comment "A pathogen colonization of host phenotype which affects the vegetative growth or proliferation of the pathogen on the host surface." ;
rdfs:subClassOf obo:PHIPO_0000332 .
obo:CHEBI_26195 a rdfs:Class ;
rdfs:label "polyphenol" ;
rdfs:comment "Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group." ;
rdfs:subClassOf obo:CHEBI_33853 .
obo:GO_0002351 a rdfs:Class ;
rdfs:label "serotonin production involved in inflammatory response" ;
rdfs:comment "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0002532 .
obo:GO_0099068 a rdfs:Class ;
rdfs:label "postsynapse assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a postsynapse." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0022607 , obo:GO_0099173 .
obo:GO_0002396 a rdfs:Class ;
rdfs:label "MHC protein complex assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0065003 .
obo:GO_0031114 a rdfs:Class ;
rdfs:label "regulation of microtubule depolymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of microtubule depolymerization." ;
rdfs:subClassOf obo:GO_0031110 , obo:GO_0065007 , obo:GO_1901879 , obo:GO_1902903 .
obo:CHEBI_35498 a rdfs:Class ;
rdfs:label "diuretic" ;
rdfs:comment "An agent that promotes the excretion of urine through its effects on kidney function." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:CHEBI_26895 a rdfs:Class ;
rdfs:label "tetracyclines" ;
rdfs:comment "A subclass of polyketides having an octahydrotetracene-2-carboxamide skeleton, substituted with many hydroxy and other groups." ;
rdfs:subClassOf obo:CHEBI_26188 .
obo:CHEBI_33572 a rdfs:Class ;
rdfs:label "resorcinols" ;
rdfs:comment "Any benzenediol in which the two hydroxy groups are meta to one another." ;
rdfs:subClassOf obo:CHEBI_33570 .
obo:CL_0010006 a rdfs:Class ;
rdfs:label "cardiac blood vessel endothelial cell" ;
rdfs:comment "Any blood vessel endothelial cell that is part of some heart." ;
rdfs:subClassOf obo:CL_0000071 , obo:CL_0010008 .
obo:PHIPO_0000590 a rdfs:Class ;
rdfs:label "resistance to voriconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to voriconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
a rdfs:Class ;
rdfs:label "Pons, sensory related" ;
rdfs:subClassOf obo:BFO_0000004 .
obo:GO_1905522 a rdfs:Class ;
rdfs:label "negative regulation of macrophage migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0071676 , obo:GO_1905521 .
obo:CL_4300349 a rdfs:Class ;
rdfs:label "Purkinje layer interneuron (Mmus)" ;
rdfs:comment "A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Rgs6 (Mmus), Slc6a5 (Mmus), Shisa9 (Mmus), Zic1 (Mmus), Bmp6 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:309 CB PLI Gly-Gaba." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4072102 , obo:CL_4300028 .
obo:GO_1901607 a rdfs:Class ;
rdfs:label "alpha-amino acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of an alpha-amino acid." ;
rdfs:subClassOf obo:GO_0008652 , obo:GO_0009058 , obo:GO_0046394 , obo:GO_1901605 .
obo:GO_1902019 a rdfs:Class ;
rdfs:label "regulation of cilium-dependent cell motility" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cilium-dependent cell motility." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000145 .
obo:GO_1902850 a rdfs:Class ;
rdfs:label "microtubule cytoskeleton organization involved in mitosis" ;
rdfs:comment "Any microtubule cytoskeleton organization that is involved in mitosis." ;
rdfs:subClassOf obo:GO_0000226 , obo:GO_1903047 .
obo:GO_2000826 a rdfs:Class ;
rdfs:label "regulation of heart morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of heart morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000027 .
obo:PHIPO_0000620 a rdfs:Class ;
rdfs:label "resistance to fenpropidin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fenpropidin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1903951 a rdfs:Class ;
rdfs:label "positive regulation of AV node cell action potential" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of AV node cell action potential." ;
rdfs:subClassOf obo:GO_0045760 , obo:GO_0065007 , obo:GO_0098904 .
obo:GO_0061032 a rdfs:Class ;
rdfs:label "visceral serous pericardium development" ;
rdfs:comment "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0032350 a rdfs:Class ;
rdfs:label "regulation of hormone metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ;
rdfs:subClassOf obo:GO_0010817 , obo:GO_0019222 , obo:GO_0065007 .
obo:CL_4300362 a rdfs:Class ;
rdfs:label "tanycyte (Mmus)" ;
rdfs:comment "A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Apoe (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:322 Tanycyte NN." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0002085 .
obo:GO_0006403 a rdfs:Class ;
rdfs:label "RNA localization" ;
rdfs:comment "A process in which RNA is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0033036 .
obo:UBERON_0001145 a rdfs:Class ;
rdfs:label "ovarian vein" ;
rdfs:comment "A vein that carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0015212 .
obo:GO_0019218 a rdfs:Class ;
rdfs:label "regulation of steroid metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids." ;
rdfs:subClassOf obo:GO_0019216 , obo:GO_0065007 .
obo:GO_0044089 a rdfs:Class ;
rdfs:label "positive regulation of cellular component biogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." ;
rdfs:subClassOf obo:GO_0044087 , obo:GO_0048522 , obo:GO_0065007 .
obo:PHIPO_0001410 a rdfs:Class ;
rdfs:label "normal growth on iprovalicarb" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to iprovalicarb (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CL_4023017 a rdfs:Class ;
rdfs:label "sst GABAergic interneuron" ;
rdfs:comment "A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses somatostatin (sst) and derived from the MGE." ;
rdfs:subClassOf obo:CL_4023069 .
obo:CL_0000347 a rdfs:Class ;
rdfs:label "scleral cell" ;
rdfs:comment "A cell of the sclera of the eye." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_0042552 a rdfs:Class ;
rdfs:label "myelination" ;
rdfs:comment "The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." ;
rdfs:subClassOf obo:GO_0008366 .
obo:PHIPO_0000897 a rdfs:Class ;
rdfs:label "sensitive to enrofloxacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to enrofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0000792 a rdfs:Class ;
rdfs:label "heterochromatin" ;
rdfs:comment "A compact and highly condensed form of chromatin that is refractory to transcription." ;
rdfs:subClassOf obo:GO_0000785 .
obo:UBERON_0000109 a rdfs:Class ;
rdfs:label "gastrula stage" ;
rdfs:comment "A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:CHEBI_13248 a rdfs:Class ;
rdfs:label "anilide" ;
rdfs:comment "Any aromatic amide obtained by acylation of aniline." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_62733 .
obo:GO_1904413 a rdfs:Class ;
rdfs:label "negative regulation of cardiac ventricle development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1904412 .
obo:GO_0044419 a rdfs:Class ;
rdfs:label "biological process involved in interspecies interaction between organisms" ;
rdfs:comment "Any process evolved to enable an interaction with an organism of a different species." ;
rdfs:subClassOf obo:GO_0008150 .
obo:BFO_0000015 a rdfs:Class ;
rdfs:label "process"@en ;
rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
rdfs:subClassOf obo:BFO_0000003 .
obo:GO_0045665 a rdfs:Class ;
rdfs:label "negative regulation of neuron differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0045664 , obo:GO_0065007 .
obo:GO_0048864 a rdfs:Class ;
rdfs:label "stem cell development" ;
rdfs:comment "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:GO_0042098 a rdfs:Class ;
rdfs:label "T cell proliferation" ;
rdfs:comment "The expansion of a T cell population by cell division. Follows T cell activation." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0042110 , obo:GO_0046651 .
obo:CL_4310093 a rdfs:Class ;
rdfs:label "GPe MEIS2-SOX6 GABA arkypallidal neuron (Primate)" ;
rdfs:comment "A arkypallidal neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe MEIS2-SOX6 GABA." ;
rdfs:subClassOf obo:CL_0020010 .
obo:CHEBI_4877 a rdfs:Class ;
rdfs:label "ethambutol" ;
rdfs:comment "An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone." ;
rdfs:subClassOf obo:CHEBI_23981 , obo:CHEBI_31577 , obo:CHEBI_50995 .
obo:GO_1901889 a rdfs:Class ;
rdfs:label "negative regulation of cell junction assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1901888 .
obo:CHEBI_28077 a rdfs:Class ;
rdfs:label "rifampicin" ;
rdfs:comment "A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei)." ;
rdfs:subClassOf obo:CHEBI_26580 , obo:CHEBI_38532 , obo:CHEBI_46847 , obo:CHEBI_46920 , obo:CHEBI_59779 , obo:CHEBI_72588 .
obo:GO_0032790 a rdfs:Class ;
rdfs:label "ribosome disassembly" ;
rdfs:comment "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_1903008 .
obo:GO_1900015 a rdfs:Class ;
rdfs:label "regulation of cytokine production involved in inflammatory response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response." ;
rdfs:subClassOf obo:GO_0001817 , obo:GO_0065007 .
obo:CL_1000223 a rdfs:Class ;
rdfs:label "pulmonary neuroendocrine cell" ;
rdfs:comment "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury." ;
rdfs:subClassOf obo:CL_0000006 , obo:CL_0000098 , obo:CL_0000165 , obo:CL_0000206 , obo:CL_0000458 , obo:CL_1000272 .
obo:GO_1904457 a rdfs:Class ;
rdfs:label "positive regulation of neuronal action potential" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuronal action potential." ;
rdfs:subClassOf obo:GO_0045760 , obo:GO_0051971 , obo:GO_0065007 , obo:GO_0098908 .
obo:UBERON_0010254 a rdfs:Class ;
rdfs:label "2nd arch mesenchyme from neural crest" ;
rdfs:comment "Mesenchyme that develops_from a neural crest and is part of a 2nd arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005689 , obo:UBERON_0007213 , obo:UBERON_0010359 .
obo:CHEBI_60004 a rdfs:Class ;
rdfs:label "mixture" ;
rdfs:comment "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." ;
rdfs:subClassOf obo:CHEBI_59999 .
obo:CL_4307042 a rdfs:Class ;
rdfs:label "Astro-TE NN_2 Clstn2 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gm6145 (Mmus), E330013P04Rik (Mmus), Slc39a12 (Mmus). It is distinguished from other Astro-TE NN_2 cells by expression of Clstn2. These cells are located in the Hippocampal region , in or close to the regions: Dentate gyrus, molecular layer, Dentate gyrus, polymorph layer, Field CA3, stratum oriens, Dentate gyrus, granule cell layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5222 Astro-TE NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301592 .
obo:PATO_0002418 a rdfs:Class ;
rdfs:label "acidophilic" ;
rdfs:comment "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions." ;
rdfs:subClassOf obo:PATO_0070045 .
obo:CL_0000686 a rdfs:Class ;
rdfs:label "cerebrospinal fluid secreting cell" ;
rdfs:comment "A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000710 , obo:CL_1100001 .
obo:PHIPO_0001222 a rdfs:Class ;
rdfs:label "cell viability phenotype"@en ;
rdfs:comment "A single species cell phenotype that consists of the cell's disposition to survive and develop normally." ;
rdfs:subClassOf obo:PHIPO_0000034 .
obo:PHIPO_0000211 a rdfs:Class ;
rdfs:label "obsolete decreased stature" .
obo:CL_1000274 a rdfs:Class ;
rdfs:label "trophectodermal cell" ;
rdfs:comment "An extraembryonic cell that is part of the trophectoderm, representing the first lineage to differentiate in the embryo. This cell is crucial for implantation into the uterine wall and differentiates into trophoblast cells, which contribute to placenta formation and facilitate maternal-fetal nutrient and signal exchange." ;
rdfs:subClassOf obo:CL_0000349 .
obo:PR_P97797 a rdfs:Class ;
rdfs:label "tyrosine-protein phosphatase non-receptor type substrate 1 (mouse)" ;
rdfs:comment "A tyrosine-protein phosphatase non-receptor type substrate 1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001968 , obo:PR_000029032 .
obo:PHIPO_0000751 a rdfs:Class ;
rdfs:label "sensitive to fludioxonil"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fludioxonil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000616 a rdfs:Class ;
rdfs:label "resistance to kanamycin A"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to kanamycin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_2001050 a rdfs:Class ;
rdfs:label "negative regulation of tendon cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0065007 , obo:GO_2001049 .
obo:CHEBI_145565 a rdfs:Class ;
rdfs:label "macrolide lactam" ;
rdfs:comment "A macrolide in which the macrocyclic lactone ring includes an amide group." ;
rdfs:subClassOf obo:CHEBI_24995 , obo:CHEBI_25106 .
obo:GO_1903789 a rdfs:Class ;
rdfs:label "regulation of amino acid transmembrane transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of amino acid transmembrane transport." ;
rdfs:subClassOf obo:GO_0034762 , obo:GO_0051955 , obo:GO_0065007 .
obo:CL_4307038 a rdfs:Class ;
rdfs:label "Astro-TE NN_1 Myoc astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Lhx2 (Mmus), Kcne1l (Mmus), Alpk1 (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Kcne1l, Alpk1. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5218 Astro-TE NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301591 .
obo:PHIPO_0000870 a rdfs:Class ;
rdfs:label "sensitive to miconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to miconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0071887 a rdfs:Class ;
rdfs:label "leukocyte apoptotic process" ;
rdfs:comment "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ;
rdfs:subClassOf obo:GO_0006915 .
obo:CHEBI_26979 a rdfs:Class ;
rdfs:label "organic heterotricyclic compound" ;
rdfs:comment "An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms." ;
rdfs:subClassOf obo:CHEBI_36688 , obo:CHEBI_38166 , obo:CHEBI_51959 .
obo:GO_1903530 a rdfs:Class ;
rdfs:label "regulation of secretion by cell" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of secretion by cell." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0051046 , obo:GO_0065007 .
obo:GO_0003216 a rdfs:Class ;
rdfs:label "cardiac left atrium formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts." ;
rdfs:subClassOf obo:GO_0003210 , obo:GO_0048646 .
obo:GO_0001936 a rdfs:Class ;
rdfs:label "regulation of endothelial cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation." ;
rdfs:subClassOf obo:GO_0050678 , obo:GO_0065007 .
obo:GO_0090290 a rdfs:Class ;
rdfs:label "positive regulation of osteoclast proliferation" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070665 , obo:GO_0090289 .
obo:CL_0011030 a rdfs:Class ;
rdfs:label "dermal microvascular endothelial cell" ;
rdfs:comment "Any microvascular endothelial cell that is part of the dermis." ;
rdfs:subClassOf obo:CL_2000008 , obo:CL_2000010 .
obo:UBERON_0005769 a rdfs:Class ;
rdfs:label "basement membrane of epithelium" ;
rdfs:comment "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." ;
rdfs:subClassOf obo:UBERON_0005764 .
obo:CHEBI_35358 a rdfs:Class ;
rdfs:label "sulfonamide" ;
rdfs:comment "An amide of a sulfonic acid RS(=O)2NR'2." ;
rdfs:subClassOf obo:CHEBI_33256 , obo:CHEBI_33261 , obo:CHEBI_33552 .
obo:GO_0021616 a rdfs:Class ;
rdfs:label "glossopharyngeal nerve formation" ;
rdfs:comment "The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." ;
rdfs:subClassOf obo:GO_0021603 , obo:GO_0048646 .
obo:CHEBI_26115 a rdfs:Class ;
rdfs:label "phytoalexin" ;
rdfs:comment "A toxin made by a plant that acts against an organism attacking it." ;
rdfs:subClassOf obo:CHEBI_38231 .
obo:CHEBI_51372 a rdfs:Class ;
rdfs:label "neuromuscular agent" ;
rdfs:comment "A drug used for its actions on skeletal muscle." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:CHEBI_16976 a rdfs:Class ;
rdfs:label "hygromycin B" ;
rdfs:subClassOf obo:CHEBI_24753 , obo:CHEBI_71989 .
obo:UBERON_0003339 a rdfs:Class ;
rdfs:label "ganglion of central nervous system" ;
rdfs:comment "A ganglion that is part of a central nervous system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000045 .
obo:PHIPO_0001415 a rdfs:Class ;
rdfs:label "sensitive to thifluzamide" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to thifluzamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0010272 a rdfs:Class ;
rdfs:label "hyoid apparatus" ;
rdfs:comment "A group of bones comprised of hyoid body and two pairs of cornua (i.e. greater cornua and lesser cornua), and lies just below the tongue, above the thyroid cartilage." ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:GO_2000352 a rdfs:Class ;
rdfs:label "negative regulation of endothelial cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0065007 , obo:GO_2000351 .
obo:GO_0070633 a rdfs:Class ;
rdfs:label "transepithelial transport" ;
rdfs:comment "The directed movement of a substance from one side of an epithelium to the other." ;
rdfs:subClassOf obo:GO_0006810 .
obo:GO_0070344 a rdfs:Class ;
rdfs:label "regulation of fat cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of fat cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:CL_4023063 a rdfs:Class ;
rdfs:label "medial ganglionic eminence derived interneuron" ;
rdfs:comment "An interneuron that is derived from the medial ganglionic eminence. In mice and humans, it expresses LHX6 and SOX6." ;
rdfs:subClassOf obo:CL_0000099 .
obo:UBERON_0000117 a rdfs:Class ;
rdfs:label "respiratory tube" ;
rdfs:comment "A tube in the respiratory system. Examples: bronchus, bronchiole, trachea." ;
rdfs:subClassOf obo:UBERON_0000025 .
obo:UBERON_0001085 a rdfs:Class ;
rdfs:label "skin of trunk" ;
rdfs:comment "A zone of skin that is part of a trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000014 .
obo:CHEBI_36841 a rdfs:Class ;
rdfs:label "11-hydroxy steroid" ;
rdfs:subClassOf obo:CHEBI_35350 .
obo:PHIPO_0000828 a rdfs:Class ;
rdfs:label "sensitive to tricyclazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tricyclazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0010070 a rdfs:Class ;
rdfs:label "zygote asymmetric cell division" ;
rdfs:comment "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials." ;
rdfs:subClassOf obo:GO_0008356 .
obo:NCBITaxon_33154 a rdfs:Class ;
rdfs:label "Opisthokonta" ;
rdfs:subClassOf obo:NCBITaxon_2759 .
obo:UBERON_0005427 a rdfs:Class ;
rdfs:label "corneal primordium" ;
rdfs:comment "Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea." ;
rdfs:subClassOf obo:UBERON_0000479 , obo:UBERON_0001048 , obo:UBERON_0010313 .
obo:CHEBI_76725 a rdfs:Class ;
rdfs:label "EC 1.* (oxidoreductase) inhibitor" ;
rdfs:comment "An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*)." ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:UBERON_0001895 a rdfs:Class ;
rdfs:label "metencephalon" ;
rdfs:comment "Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]." ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0004733 .
obo:GO_0002733 a rdfs:Class ;
rdfs:label "regulation of myeloid dendritic cell cytokine production" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production." ;
rdfs:subClassOf obo:GO_0002730 , obo:GO_0002886 , obo:GO_0065007 .
obo:UBERON_0035044 a rdfs:Class ;
rdfs:label "olfactory cortex layer 3" ;
rdfs:comment "Deepest layer of olfactory cortex." ;
rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0022303 .
obo:UBERON_0011234 a rdfs:Class ;
rdfs:label "fibrous membrane of synovial tendon sheath" ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:CHEBI_4031 a rdfs:Class ;
rdfs:label "cyclosporin A" ;
rdfs:comment "A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle." ;
rdfs:subClassOf obo:CHEBI_24613 .
obo:CHEBI_83319 a rdfs:Class ;
rdfs:label "EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor" ;
rdfs:comment "An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of Δ14-sterol reductase (EC 1.3.1.70)." ;
rdfs:subClassOf obo:CHEBI_76857 .
obo:PHIPO_0000408 a rdfs:Class ;
rdfs:label "obsolete morphology phenotype" .
obo:CHEBI_50846 a rdfs:Class ;
rdfs:label "immunomodulator" ;
rdfs:comment "Biologically active substance whose activity affects or plays a role in the functioning of the immune system." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_24432 .
obo:GO_0034097 a rdfs:Class ;
rdfs:label "response to cytokine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus." ;
rdfs:subClassOf obo:GO_1901652 .
obo:GO_0086017 a rdfs:Class ;
rdfs:label "Purkinje myocyte action potential" ;
rdfs:comment "An action potential that occurs in a Purkinje myocyte." ;
rdfs:subClassOf obo:GO_0001508 , obo:GO_0086001 .
obo:UBERON_0004139 a rdfs:Class ;
rdfs:label "cardiogenic plate" ;
rdfs:comment "The first recognizable structure derived from the heart field." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0048738 a rdfs:Class ;
rdfs:label "cardiac muscle tissue development" ;
rdfs:comment "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0014706 , obo:GO_0048856 .
obo:UBERON_0001726 a rdfs:Class ;
rdfs:label "papilla of tongue" ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:CL_0000459 a rdfs:Class ;
rdfs:label "noradrenergic cell" ;
rdfs:comment "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000457 .
obo:UBERON_0001586 a rdfs:Class ;
rdfs:label "internal jugular vein" ;
rdfs:comment "One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0004711 .
obo:GO_0060932 a rdfs:Class ;
rdfs:label "His-Purkinje system cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0055007 .
obo:GO_0060349 a rdfs:Class ;
rdfs:label "bone morphogenesis" ;
rdfs:comment "The process in which bones are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:UBERON_0011821 a rdfs:Class ;
rdfs:label "irregular connective tissue" ;
rdfs:comment "Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:UBERON_0001013 a rdfs:Class ;
rdfs:label "adipose tissue" ;
rdfs:comment "Portion of connective tissue composed of adipocytes enmeshed in areolar tissue." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0011822 .
obo:PHIPO_0001320 a rdfs:Class ;
rdfs:label "sensitive to metalaxyl"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to metalaxyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_62733 a rdfs:Class ;
rdfs:label "aromatic amide" ;
rdfs:comment "An amide in which the amide linkage is bonded directly to an aromatic system." ;
rdfs:subClassOf obo:CHEBI_32988 , obo:CHEBI_33659 .
obo:PHIPO_0000341 a rdfs:Class ;
rdfs:label "obsolete gain of pathogen cell to cell migration within host" ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally within the host organism is gained (pathogen migration was absent within the host and is now present)." .
obo:CHEBI_87068 a rdfs:Class ;
rdfs:label "imidazole fungicide" ;
rdfs:comment "Any imidazole antifungal agent that has been used as a fungicide." ;
rdfs:subClassOf obo:CHEBI_86420 .
obo:CHEBI_17658 a rdfs:Class ;
rdfs:label "tylosin" ;
rdfs:comment "A macrolide antibiotic that is tylonolide having mono- and diglycosyl moieties attached to two of its hydroxy groups. It is found naturally as a fermentation product of Streptomyces fradiae." ;
rdfs:subClassOf obo:CHEBI_17478 , obo:CHEBI_25022 , obo:CHEBI_25105 , obo:CHEBI_28963 , obo:CHEBI_51689 , obo:CHEBI_63353 , obo:CHEBI_63367 .
obo:GO_0045927 a rdfs:Class ;
rdfs:label "positive regulation of growth" ;
rdfs:comment "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." ;
rdfs:subClassOf obo:GO_0040008 , obo:GO_0048518 , obo:GO_0065007 .
obo:PR_P05532 a rdfs:Class ;
rdfs:label "mast/stem cell growth factor receptor Kit (mouse)" ;
rdfs:comment "A mast/stem cell growth factor receptor that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000002065 , obo:PR_000029032 .
obo:PHIPO_0001262 a rdfs:Class ;
rdfs:label "host defense-induced protein level phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, which affects the level of a host produced protein during infection." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:GO_0009967 a rdfs:Class ;
rdfs:label "positive regulation of signal transduction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of signal transduction." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0010647 , obo:GO_0023056 , obo:GO_0048584 , obo:GO_0065007 .
obo:CHEBI_35131 a rdfs:Class ;
rdfs:label "aldose phosphate" ;
rdfs:subClassOf obo:CHEBI_33447 .
obo:UBERON_0000988 a rdfs:Class ;
rdfs:label "pons" ;
rdfs:comment "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:CL_0000094 a rdfs:Class ;
rdfs:label "granulocyte" ;
rdfs:comment "A leukocyte with abundant granules in the cytoplasm." ;
rdfs:subClassOf obo:CL_0000081 , obo:CL_0000766 .
obo:GO_0003228 a rdfs:Class ;
rdfs:label "atrial cardiac muscle tissue development" ;
rdfs:comment "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048738 , obo:GO_0048856 .
obo:CHEBI_17478 a rdfs:Class ;
rdfs:label "aldehyde" ;
rdfs:comment "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group." ;
rdfs:subClassOf obo:CHEBI_36586 .
obo:CHEBI_139592 a rdfs:Class ;
rdfs:label "tertiary alpha-hydroxy ketone" ;
rdfs:comment "An α-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups." ;
rdfs:subClassOf obo:CHEBI_139588 , obo:CHEBI_26878 .
obo:UBERON_0005396 a rdfs:Class ;
rdfs:label "carotid artery segment" ;
rdfs:comment "One of: the common carotid artery, or its branches, the external and internal carotid arteries." ;
rdfs:subClassOf obo:UBERON_0004573 .
obo:GO_0001824 a rdfs:Class ;
rdfs:label "blastocyst development" ;
rdfs:comment "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. The blastula follows the morula and precedes the gastrula in the developmental sequence." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_48377 a rdfs:Class ;
rdfs:label "imidic acid" ;
rdfs:comment "Compounds derived from oxoacids RkE(=O)l(OH)m (l ≠ 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH)." ;
rdfs:subClassOf obo:CHEBI_33241 , obo:CHEBI_51143 .
obo:GO_0032880 a rdfs:Class ;
rdfs:label "regulation of protein localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0060341 , obo:GO_0065007 .
obo:CHEBI_34653 a rdfs:Class ;
rdfs:label "Congo Red" ;
rdfs:comment "An indicator dye that is blue-violet at pH 3.0 and red at pH 5.0." ;
rdfs:subClassOf obo:CHEBI_48960 .
obo:UBERON_0000358 a rdfs:Class ;
rdfs:label "blastocyst" ;
rdfs:comment "The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:CHEBI_138675 a rdfs:Class ;
rdfs:label "gas molecular entity" ;
rdfs:comment "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." ;
rdfs:subClassOf obo:CHEBI_33579 .
obo:PHIPO_0001184 a rdfs:Class ;
rdfs:label "obsolete loss of functional host resistance gene" ;
rdfs:comment "A phenotype where the ability of a host to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene is abolished (resistance was present and is now absent)." .
obo:GO_0051621 a rdfs:Class ;
rdfs:label "regulation of norepinephrine uptake" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:GO_0097014 a rdfs:Class ;
rdfs:label "ciliary plasm" ;
rdfs:comment "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." ;
rdfs:subClassOf obo:GO_0005737 .
obo:GO_0061298 a rdfs:Class ;
rdfs:label "retina vasculature development in camera-type eye" ;
rdfs:comment "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0001944 , obo:GO_0048856 .
obo:GO_0042442 a rdfs:Class ;
rdfs:label "melatonin catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine)." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0030186 , obo:GO_0042436 , obo:GO_0042447 .
obo:GO_0006810 a rdfs:Class ;
rdfs:label "transport" ;
rdfs:comment "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." ;
rdfs:subClassOf obo:GO_0051234 .
obo:UBERON_0006964 a rdfs:Class ;
rdfs:label "pars distalis of adenohypophysis" ;
rdfs:comment "The distal part of adenohypophysis: the part that makes up the main body of the gland." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0005156 .
obo:GO_0021566 a rdfs:Class ;
rdfs:label "hypoglossal nerve development" ;
rdfs:comment "The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." ;
rdfs:subClassOf obo:GO_0021545 , obo:GO_0048856 .
obo:CHEBI_5435 a rdfs:Class ;
rdfs:label "piperidine-2,6-dione" ;
rdfs:comment "A dicarboximide that is piperidine which is substituted by oxo groups at positions 2 and 6." ;
rdfs:subClassOf obo:CHEBI_35356 , obo:CHEBI_48589 .
obo:CL_4307104 a rdfs:Class ;
rdfs:label "MOL NN_4 Plin3 mature myelinating oligodendrocyte (Mmus)" ;
rdfs:comment "A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prr5l (Mmus), Hapln2 (Mmus), Enpp6 (Mmus), Grm7 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Plin3, Grm7. These cells are located in the Medulla, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5284 MOL NN_4." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301614 .
obo:GO_0048513 a rdfs:Class ;
rdfs:label "animal organ development" ;
rdfs:comment "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0005744 a rdfs:Class ;
rdfs:label "bone foramen" ;
rdfs:comment "Anatomical space that is an opening in a bone, usually for passage of blood vessels or nerves." ;
rdfs:subClassOf obo:UBERON_0004111 .
obo:GO_1904831 a rdfs:Class ;
rdfs:label "positive regulation of aortic smooth muscle cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904829 , obo:GO_1905065 .
obo:PHIPO_0000890 a rdfs:Class ;
rdfs:label "sensitive to fluconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fluconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0003404 a rdfs:Class ;
rdfs:label "optic vesicle morphogenesis" ;
rdfs:comment "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048598 , obo:GO_0048729 .
obo:UBERON_0004831 a rdfs:Class ;
rdfs:label "esophagus skeletal muscle" ;
rdfs:comment "A portion of skeletal muscle tissue that is part of a esophagus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001134 .
obo:PHIPO_0000206 a rdfs:Class ;
rdfs:label "obsolete altered pathogen and host protein binding specificity" ;
rdfs:comment "A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs with a different specificity than normal." .
obo:CHEBI_83906 a rdfs:Class ;
rdfs:label "(S)-diniconazole" ;
rdfs:comment "A (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol that is the (S)-enantiomer of diniconazole." ;
rdfs:subClassOf obo:CHEBI_83909 .
obo:GO_0048581 a rdfs:Class ;
rdfs:label "negative regulation of post-embryonic development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ;
rdfs:subClassOf obo:GO_0048580 , obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 .
obo:UBERON_0013768 a rdfs:Class ;
rdfs:label "great vessel of heart" ;
rdfs:comment "Great vessels is a term used to refer collectively to the large vessels that bring blood to and from the heart." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:CHEBI_26830 a rdfs:Class ;
rdfs:label "sulfonium compound" ;
rdfs:subClassOf obo:CHEBI_26835 .
obo:CHEBI_28295 a rdfs:Class ;
rdfs:label "2-deoxystreptamine" ;
rdfs:comment "An amino cyclitol consisting of scyllo-inositol with the hydroxy groups at positions 1 and 3 replaced by unsubstituted amino groups and that at position 2 replaced by hydrogen." ;
rdfs:subClassOf obo:CHEBI_61689 .
obo:CHEBI_33281 a rdfs:Class ;
rdfs:label "antimicrobial agent" ;
rdfs:comment "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_86411 a rdfs:Class ;
rdfs:label "cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine" ;
rdfs:comment "Either of the two diastereoisomers of 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine in which the imidazol-1-ylmethyl group and the aryloxymethyl group are in a cis relationship to each other - i.e. they are both on the same side of the plane of the dioxolane ring. The antifungal drug ketoconazole is a racemic mixture of the two cis diastereoisomers." ;
rdfs:subClassOf obo:CHEBI_48339 .
obo:CL_4042018 a rdfs:Class ;
rdfs:label "alpha2-tanycyte"@en ;
rdfs:comment "Tanycyte of the third ventricle, located immediately ventral to alpha-1 tanycytes. These cells project to the ventromedial and arcuate nuclei of the hypothalamus and express the glial marker S-100β." ;
rdfs:subClassOf obo:CL_0002085 .
obo:GO_2000509 a rdfs:Class ;
rdfs:label "negative regulation of dendritic cell chemotaxis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis." ;
rdfs:subClassOf obo:GO_0002689 , obo:GO_0065007 , obo:GO_0071676 , obo:GO_2000508 .
obo:GO_0051654 a rdfs:Class ;
rdfs:label "establishment of mitochondrion localization" ;
rdfs:comment "The directed movement of the mitochondrion to a specific location." ;
rdfs:subClassOf obo:GO_0051234 , obo:GO_0051646 , obo:GO_0051656 .
obo:GO_0010628 a rdfs:Class ;
rdfs:label "positive regulation of gene expression" ;
rdfs:comment "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0010557 , obo:GO_0065007 .
obo:CL_0000011 a rdfs:Class ;
rdfs:label "migratory trunk neural crest cell" ;
rdfs:comment "Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination." ;
rdfs:subClassOf obo:CL_0000333 .
obo:CL_0000079 a rdfs:Class ;
rdfs:label "stratified epithelial cell" ;
rdfs:comment "An epithelial cell, organized into multiple layers, with only the basal layer being in contact with the basement membrane." ;
rdfs:subClassOf obo:CL_0000066 .
obo:UBERON_0003519 a rdfs:Class ;
rdfs:label "thoracic cavity blood vessel" ;
rdfs:comment "A blood vessel that is part of a thoracic cavity [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:UBERON_0014907 a rdfs:Class ;
rdfs:label "intersomitic vessel" ;
rdfs:comment "One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0004120 .
obo:PHIPO_0001337 a rdfs:Class ;
rdfs:label "sensitive to fluazinam"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fluazinam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0004233 a rdfs:Class ;
rdfs:label "lower respiratory tract smooth muscle" ;
rdfs:comment "A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004225 .
obo:CL_4023168 a rdfs:Class ;
rdfs:label "somatosensory neuron" ;
rdfs:comment "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000032 .
obo:UBERON_0010362 a rdfs:Class ;
rdfs:label "endoskeleton" ;
rdfs:comment "Skeletal subdivision that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:GO_0031253 a rdfs:Class ;
rdfs:label "cell projection membrane" ;
rdfs:comment "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0098590 .
obo:GO_1905432 a rdfs:Class ;
rdfs:label "regulation of retrograde trans-synaptic signaling by neuropeptide" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0099177 .
obo:UBERON_0006929 a rdfs:Class ;
rdfs:label "glandular columnar epithelium" ;
rdfs:comment "Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000485 , obo:UBERON_0006799 .
obo:GO_0010324 a rdfs:Class ;
rdfs:label "membrane invagination" ;
rdfs:comment "The infolding of a membrane." ;
rdfs:subClassOf obo:GO_0061024 .
obo:GO_0098799 a rdfs:Class ;
rdfs:label "outer mitochondrial membrane protein complex" ;
rdfs:comment "Any protein complex that is part of the outer mitochondrial membrane." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0098796 , obo:GO_0098798 .
obo:GO_0051239 a rdfs:Class ;
rdfs:label "regulation of multicellular organismal process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:CHEBI_17203 a rdfs:Class ;
rdfs:label "L-proline" ;
rdfs:comment "Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group α to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles." ;
rdfs:subClassOf obo:CHEBI_24318 , obo:CHEBI_26271 .
obo:GO_0098635 a rdfs:Class ;
rdfs:label "protein complex involved in cell-cell adhesion" ;
rdfs:comment "Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0098636 .
obo:PHIPO_0001088 a rdfs:Class ;
rdfs:label "decreased rate of hyphae formation"@en ;
rdfs:comment "An individual organism growth phenotype in which the rate, or speed, of hyphae formation is decreased." ;
rdfs:subClassOf obo:PHIPO_0001212 .
obo:PR_000001836 a rdfs:Class ;
rdfs:label "CD7 molecule" ;
rdfs:comment "A protein that is a translation product of the human CD7 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
a rdfs:Class ;
rdfs:label "lateral ventricle" ;
rdfs:subClassOf , obo:UBERON_0002285 .
obo:GO_0031273 a rdfs:Class ;
rdfs:label "negative regulation of pseudopodium assembly" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia." ;
rdfs:subClassOf obo:GO_0031272 , obo:GO_0065007 , obo:GO_0120033 .
obo:GO_1905772 a rdfs:Class ;
rdfs:label "positive regulation of mesodermal cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0065007 , obo:GO_1905770 .
obo:GO_0021906 a rdfs:Class ;
rdfs:label "hindbrain-spinal cord boundary formation" ;
rdfs:comment "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary." ;
rdfs:subClassOf obo:GO_0048646 , obo:GO_0048859 .
obo:UBERON_0018135 a rdfs:Class ;
rdfs:label "fibrocollagenous connective tissue" ;
rdfs:subClassOf obo:UBERON_0011824 .
obo:GO_0014032 a rdfs:Class ;
rdfs:label "neural crest cell development" ;
rdfs:comment "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048864 .
obo:PHIPO_0000268 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction vacuolar transport" ;
rdfs:comment "A pathogen host interaction (cellular process??) phenotype in which vacuolar transport is abnormal." .
obo:UBERON_0003289 a rdfs:Class ;
rdfs:label "meninx of telencephalon" ;
rdfs:comment "A meninx that is part of a telencephalon [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002360 , obo:UBERON_0003548 .
obo:GO_0006508 a rdfs:Class ;
rdfs:label "proteolysis" ;
rdfs:comment "The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds." ;
rdfs:subClassOf obo:GO_0019538 .
obo:GO_0009725 a rdfs:Class ;
rdfs:label "response to hormone" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." ;
rdfs:subClassOf obo:GO_0009719 , obo:GO_0042221 .
obo:GO_0062033 a rdfs:Class ;
rdfs:label "positive regulation of mitotic sister chromatid segregation" ;
rdfs:comment "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." ;
rdfs:subClassOf obo:GO_0033047 , obo:GO_0051984 , obo:GO_0065007 , obo:GO_2001252 .
obo:UBERON_0035554 a rdfs:Class ;
rdfs:label "right cardiac chamber" ;
rdfs:comment "Any chamber of the right side of the heart." ;
rdfs:subClassOf obo:UBERON_0004151 , obo:UBERON_0015212 .
obo:CHEBI_59349 a rdfs:Class ;
rdfs:label "cefepime(1+)" ;
rdfs:comment "The conjugate acid of cefepime." ;
rdfs:subClassOf obo:CHEBI_23066 .
obo:PHIPO_0001352 a rdfs:Class ;
rdfs:label "normal growth on amphotericin B"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to amphotericin B (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0045835 a rdfs:Class ;
rdfs:label "negative regulation of meiotic nuclear division" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0040020 , obo:GO_0051447 , obo:GO_0051784 , obo:GO_0065007 .
obo:PHIPO_0001432 a rdfs:Class ;
rdfs:label "normal growth on ipconazole" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to ipconazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_76924 a rdfs:Class ;
rdfs:label "plant metabolite" ;
rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." ;
rdfs:subClassOf obo:CHEBI_75763 .
obo:UBERON_0009570 a rdfs:Class ;
rdfs:label "spinal cord sulcus limitans" ;
rdfs:comment "A sulcus limitans of neural tube that is part of a future spinal cord." ;
rdfs:subClassOf obo:UBERON_0005478 .
a rdfs:Class ;
rdfs:label "fourth ventricle" ;
rdfs:subClassOf , obo:UBERON_0002422 .
obo:GO_0043244 a rdfs:Class ;
rdfs:label "regulation of protein-containing complex disassembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:CHEBI_36628 a rdfs:Class ;
rdfs:label "1,8-naphthyridine" ;
rdfs:comment "A naphthyridine in which the nitrogens are situated at positions 1 and 8." ;
rdfs:subClassOf obo:CHEBI_36624 .
obo:GO_0075010 a rdfs:Class ;
rdfs:label "regulation of germ tube formation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0140392 a rdfs:Class ;
rdfs:label "extracellular protein-containing complex" ;
rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together outside a cell." ;
rdfs:subClassOf obo:GO_0032991 .
obo:CHEBI_25367 a rdfs:Class ;
rdfs:label "molecule" ;
rdfs:comment "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_36357 .
obo:GO_0060425 a rdfs:Class ;
rdfs:label "lung morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the lung are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:CHEBI_33252 a rdfs:Class ;
rdfs:label "atomic nucleus" ;
rdfs:comment "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." ;
rdfs:subClassOf obo:CHEBI_36347 .
obo:GO_0050922 a rdfs:Class ;
rdfs:label "negative regulation of chemotaxis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ;
rdfs:subClassOf obo:GO_0032102 , obo:GO_0040013 , obo:GO_0050920 , obo:GO_0065007 .
obo:UBERON_0007373 a rdfs:Class ;
rdfs:label "inferior surface of tongue" ;
rdfs:comment "The lower (inferior) side of the tongue." ;
rdfs:subClassOf obo:UBERON_0007367 .
obo:GO_0000819 a rdfs:Class ;
rdfs:label "sister chromatid segregation" ;
rdfs:comment "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." ;
rdfs:subClassOf obo:GO_0051276 , obo:GO_0098813 .
obo:GO_0003301 a rdfs:Class ;
rdfs:label "physiological cardiac muscle hypertrophy" ;
rdfs:comment "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart." ;
rdfs:subClassOf obo:GO_0003298 , obo:GO_0003300 .
obo:GO_0014706 a rdfs:Class ;
rdfs:label "striated muscle tissue development" ;
rdfs:comment "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060537 .
obo:UBERON_0002201 a rdfs:Class ;
rdfs:label "vasculature of trunk" ;
rdfs:comment "A vasculature that is part of a trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:UBERON_0004666 a rdfs:Class ;
rdfs:label "interventricular septum membranous part" ;
rdfs:comment "The membranous portion of the wall between the two lower chambers of the heart." ;
rdfs:subClassOf obo:UBERON_0000158 , obo:UBERON_0005983 .
obo:UBERON_0002416 a rdfs:Class ;
rdfs:label "integumental system" ;
rdfs:comment "Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:GO_0045620 a rdfs:Class ;
rdfs:label "negative regulation of lymphocyte differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation." ;
rdfs:subClassOf obo:GO_0045619 , obo:GO_0051250 , obo:GO_0065007 , obo:GO_1902106 .
obo:GO_0042478 a rdfs:Class ;
rdfs:label "regulation of eye photoreceptor cell development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of eye photoreceptor development." ;
rdfs:subClassOf obo:GO_0046532 , obo:GO_0060284 , obo:GO_0065007 .
obo:PHIPO_0001114 a rdfs:Class ;
rdfs:label "decreased number of pathogen asexual sporulation structures within host lesion"@en ;
rdfs:comment "A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual sporulation structures within a host lesion is fewer than normal." ;
rdfs:subClassOf obo:PHIPO_0000469 .
obo:UBERON_0013411 a rdfs:Class ;
rdfs:label "cranial cavity" ;
rdfs:comment "Anatomical cavity that is the lumen of the skull and contains the brain." ;
rdfs:subClassOf obo:UBERON_0002553 .
obo:PHIPO_0001392 a rdfs:Class ;
rdfs:label "sensitive to metconazole" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to metconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_29007 a rdfs:Class ;
rdfs:label "ceftriaxone" ;
rdfs:comment "A third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups." ;
rdfs:subClassOf obo:CHEBI_23066 , obo:CHEBI_36816 , obo:CHEBI_38418 , obo:CHEBI_39410 .
obo:GO_0008202 a rdfs:Class ;
rdfs:label "steroid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ;
rdfs:subClassOf obo:GO_0006629 , obo:GO_0008152 .
obo:CHEBI_33745 a rdfs:Class ;
rdfs:label "copper group molecular entity" ;
rdfs:subClassOf obo:CHEBI_33676 .
obo:GO_1903429 a rdfs:Class ;
rdfs:label "regulation of cell maturation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell maturation." ;
rdfs:subClassOf obo:GO_0060284 , obo:GO_0065007 .
obo:CL_0001022 a rdfs:Class ;
rdfs:label "CD115-positive monocyte" ;
rdfs:comment "CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive." ;
rdfs:subClassOf obo:CL_0000576 , obo:CL_0000839 , obo:CL_0001019 .
obo:GO_0051446 a rdfs:Class ;
rdfs:label "positive regulation of meiotic cell cycle" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0045787 , obo:GO_0051445 , obo:GO_0065007 , obo:GO_2000243 .
obo:PHIPO_0000402 a rdfs:Class ;
rdfs:label "individual organism phenotype"@en ;
rdfs:comment "A single species phenotype that is observed at the level of an individual organism." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:GO_0045912 a rdfs:Class ;
rdfs:label "negative regulation of carbohydrate metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." ;
rdfs:subClassOf obo:GO_0006109 , obo:GO_0009892 , obo:GO_0065007 .
obo:PHIPO_0001433 a rdfs:Class ;
rdfs:label "resistance to cyprodinil" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cyprodinil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001157 a rdfs:Class ;
rdfs:label "obsolete unaltered pathogen reactive oxygen species production within host" ;
rdfs:comment "A pathogen host interaction metabolic cellular process phenotype in which the formation of reactive oxygen species (any molecules or ions formed by the incomplete one-electron reduction of oxygen) by the pathogen is unaltered within the host.(GO:1903409)" .
obo:UBERON_0015329 a rdfs:Class ;
rdfs:label "respiratory system basement membrane" ;
rdfs:comment "A basement membrane of epithelium that is part of a respiratory system." ;
rdfs:subClassOf obo:UBERON_0005769 .
obo:GO_1903625 a rdfs:Class ;
rdfs:label "negative regulation of DNA catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0051053 , obo:GO_0065007 , obo:GO_1903624 .
obo:CHEBI_33173 a rdfs:Class ;
rdfs:label "benzimidazolide" ;
rdfs:subClassOf obo:CHEBI_50335 .
obo:UBERON_0001606 a rdfs:Class ;
rdfs:label "muscle of iris" ;
rdfs:subClassOf obo:UBERON_0001630 , obo:UBERON_0011222 .
obo:PHIPO_0001244 a rdfs:Class ;
rdfs:label "increased number of pathogen asexual sporulation structures within host lesion"@en ;
rdfs:comment "A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual sporulation structures within a host lesion is greater than normal." ;
rdfs:subClassOf obo:PHIPO_0000469 .
obo:GO_1902339 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic process involved in morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904747 .
obo:GO_0009896 a rdfs:Class ;
rdfs:label "positive regulation of catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0009894 , obo:GO_0065007 .
obo:CHEBI_24278 a rdfs:Class ;
rdfs:label "glucoside" ;
rdfs:subClassOf obo:CHEBI_35313 .
obo:GO_1900116 a rdfs:Class ;
rdfs:label "extracellular negative regulation of signal transduction" ;
rdfs:comment "Any negative regulation of signal transduction that takes place in extracellular region." ;
rdfs:subClassOf obo:GO_0009968 , obo:GO_1900115 .
obo:UBERON_0005032 a rdfs:Class ;
rdfs:label "mucosa of lower lip" ;
rdfs:comment "A mucosa that is part of a lower lip [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0036294 .
obo:CHEBI_35471 a rdfs:Class ;
rdfs:label "psychotropic drug" ;
rdfs:comment "A loosely defined grouping of drugs that have effects on psychological function." ;
rdfs:subClassOf obo:CHEBI_35470 .
obo:UBERON_0003314 a rdfs:Class ;
rdfs:label "eye mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a developing camera-type eye." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0009891 .
obo:GO_0003381 a rdfs:Class ;
rdfs:label "epithelial cell morphogenesis involved in gastrulation" ;
rdfs:comment "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation." ;
rdfs:subClassOf obo:GO_0003382 .
obo:CHEBI_24648 a rdfs:Class ;
rdfs:label "hydroxamic acid anion" ;
rdfs:comment "An oxoanion resulting from the removal of a proton from the hydroxy group of any hydroxamic acid." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_35406 .
obo:CL_0000128 a rdfs:Class ;
rdfs:label "oligodendrocyte" ;
rdfs:comment "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system." ;
rdfs:subClassOf obo:CL_0000126 , obo:CL_4023154 .
obo:CHEBI_33241 a rdfs:Class ;
rdfs:label "oxoacid derivative" ;
rdfs:subClassOf obo:CHEBI_37577 .
obo:GO_1904215 a rdfs:Class ;
rdfs:label "regulation of protein import into chloroplast stroma" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma." ;
rdfs:subClassOf obo:GO_0034762 , obo:GO_0051223 , obo:GO_0065007 .
obo:CHEBI_35221 a rdfs:Class ;
rdfs:label "antimetabolite" ;
rdfs:comment "A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization." ;
rdfs:subClassOf obo:CHEBI_52206 .
obo:GO_1905629 a rdfs:Class ;
rdfs:label "positive regulation of serotonin biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0065007 , obo:GO_1905627 .
obo:CHEBI_38119 a rdfs:Class ;
rdfs:label "brassinin" ;
rdfs:subClassOf obo:CHEBI_24797 , obo:CHEBI_38129 .
obo:GO_0035260 a rdfs:Class ;
rdfs:label "internal genitalia morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0035112 .
obo:UBERON_0006920 a rdfs:Class ;
rdfs:label "esophagus squamous epithelium" ;
rdfs:comment "A squamous epithelium that is part of a esophagus." ;
rdfs:subClassOf obo:UBERON_0001976 , obo:UBERON_0006914 .
obo:GO_0097060 a rdfs:Class ;
rdfs:label "synaptic membrane" ;
rdfs:comment "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." ;
rdfs:subClassOf obo:GO_0098590 .
obo:PHIPO_0000802 a rdfs:Class ;
rdfs:label "sensitive to vancomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to vancomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0003278 a rdfs:Class ;
rdfs:label "skeleton of lower jaw" ;
rdfs:comment "A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:GO_0009914 a rdfs:Class ;
rdfs:label "hormone transport" ;
rdfs:comment "The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0010817 .
obo:GO_0030133 a rdfs:Class ;
rdfs:label "transport vesicle" ;
rdfs:comment "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." ;
rdfs:subClassOf obo:GO_0031410 .
obo:CHEBI_50176 a rdfs:Class ;
rdfs:label "keratolytic drug" ;
rdfs:comment "A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases." ;
rdfs:subClassOf obo:CHEBI_50177 .
obo:CHEBI_9215 a rdfs:Class ;
rdfs:label "spectinomycin" ;
rdfs:comment "A pyranobenzodioxin and antibiotic that is active against gram-negative bacteria and used (as its dihydrochloride pentahydrate) to treat gonorrhea. It is produced by the bacterium Streptomyces spectabilis." ;
rdfs:subClassOf obo:CHEBI_146295 , obo:CHEBI_35681 , obo:CHEBI_3992 , obo:CHEBI_50995 , obo:CHEBI_59770 , obo:CHEBI_59780 .
obo:CL_4042003 a rdfs:Class ;
rdfs:label "border associated macrophage"@en ;
rdfs:comment "A central nervous system macrophage that is part of a choroid plexus, a meninx and a perivascular space. A border associated macrophage interacts with various components of the CNS vasculature and meninges, it participates in immune surveillance and in the regulation of the blood brain barrier." ;
rdfs:subClassOf obo:CL_0000878 .
obo:UBERON_0007779 a rdfs:Class ;
rdfs:label "transudate" ;
rdfs:comment "Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces." ;
rdfs:subClassOf obo:UBERON_0000463 , obo:UBERON_0006314 .
obo:UBERON_0003380 a rdfs:Class ;
rdfs:label "cardiac muscle of left atrium" ;
rdfs:comment "A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001133 , obo:UBERON_0004490 .
obo:CHEBI_15138 a rdfs:Class ;
rdfs:label "sulfide(2-)" ;
rdfs:comment "A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide." ;
rdfs:subClassOf obo:CHEBI_79388 .
obo:GO_0060465 a rdfs:Class ;
rdfs:label "pharynx development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0003295 a rdfs:Class ;
rdfs:label "pharyngeal gland" ;
rdfs:comment "Racemose mucous glands beneath the mucous membrane of the pharynx." ;
rdfs:subClassOf obo:UBERON_0002530 , obo:UBERON_0003408 , obo:UBERON_0036225 .
obo:UBERON_0001137 a rdfs:Class ;
rdfs:label "dorsum" ;
rdfs:comment "A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.." ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:CHEBI_18140 a rdfs:Class ;
rdfs:label "hydrogen halide" ;
rdfs:subClassOf obo:CHEBI_33405 .
obo:CHEBI_46912 a rdfs:Class ;
rdfs:label "ornithinium(1+)" ;
rdfs:subClassOf obo:CHEBI_33719 .
obo:GO_0032059 a rdfs:Class ;
rdfs:label "bleb" ;
rdfs:comment "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." ;
rdfs:subClassOf obo:GO_0120025 .
obo:CL_1000306 a rdfs:Class ;
rdfs:label "fibroblast of tunica adventitia of artery" ;
rdfs:comment "A fibroblast that is part of the tunica adventitia of artery." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_4052030 .
obo:GO_1904746 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic process involved in development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0051093 , obo:GO_0065007 , obo:GO_1904748 .
obo:PHIPO_0000867 a rdfs:Class ;
rdfs:label "sensitive to streptomycin sulfate"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to streptomycin sulfate. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0048770 a rdfs:Class ;
rdfs:label "pigment granule" ;
rdfs:comment "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes." ;
rdfs:subClassOf obo:GO_0031410 .
obo:CHEBI_30911 a rdfs:Class ;
rdfs:label "glucitol" ;
rdfs:subClassOf obo:CHEBI_24583 .
obo:GO_0002615 a rdfs:Class ;
rdfs:label "positive regulation of monocyte antigen processing and presentation" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002579 , obo:GO_0002613 , obo:GO_0065007 .
obo:GO_0032543 a rdfs:Class ;
rdfs:label "mitochondrial translation" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code." ;
rdfs:subClassOf obo:GO_0006412 .
obo:CHEBI_3393 a rdfs:Class ;
rdfs:label "carbenicillin" ;
rdfs:comment "A penicillin antibiotic having a 6β-2-carboxy-2-phenylacetamido side-chain." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_88187 .
obo:GO_0045744 a rdfs:Class ;
rdfs:label "negative regulation of G protein-coupled receptor signaling pathway" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway." ;
rdfs:subClassOf obo:GO_0008277 , obo:GO_0009968 , obo:GO_0065007 .
obo:GO_1990580 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translational termination" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic translational termination." ;
rdfs:subClassOf obo:GO_0006449 , obo:GO_0050789 , obo:GO_2000765 .
obo:GO_0070192 a rdfs:Class ;
rdfs:label "chromosome organization involved in meiotic cell cycle" ;
rdfs:comment "A process of chromosome organization that is involved in a meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0051276 , obo:GO_1903046 .
obo:GO_0003206 a rdfs:Class ;
rdfs:label "cardiac chamber morphogenesis" ;
rdfs:comment "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_50694 a rdfs:Class ;
rdfs:label "minocycline" ;
rdfs:comment "A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5." ;
rdfs:subClassOf obo:CHEBI_139592 , obo:CHEBI_26895 , obo:CHEBI_48132 .
obo:CL_0002614 a rdfs:Class ;
rdfs:label "neuron of the substantia nigra" ;
rdfs:comment "A neuron of the substantia nigra." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000029 .
obo:GO_2000270 a rdfs:Class ;
rdfs:label "negative regulation of fibroblast apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0065007 , obo:GO_2000269 .
obo:CHEBI_25710 a rdfs:Class ;
rdfs:label "organophosphorus compound" ;
rdfs:comment "An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters." ;
rdfs:subClassOf obo:CHEBI_26082 , obo:CHEBI_33285 .
obo:GO_0048659 a rdfs:Class ;
rdfs:label "smooth muscle cell proliferation" ;
rdfs:comment "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0033002 .
obo:CHEBI_16042 a rdfs:Class ;
rdfs:label "halide anion" ;
rdfs:comment "A monoatomic monoanion resulting from the addition of an electron to any halogen atom." ;
rdfs:subClassOf obo:CHEBI_33429 , obo:CHEBI_79389 .
obo:CHEBI_204928 a rdfs:Class ;
rdfs:label "cefotaxime" ;
rdfs:comment "A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups." ;
rdfs:subClassOf obo:CHEBI_23066 , obo:CHEBI_36816 , obo:CHEBI_38418 .
obo:PHIPO_0001292 a rdfs:Class ;
rdfs:label "sensitive to fenpicoxamid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenpicoxamid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000634 a rdfs:Class ;
rdfs:label "resistance to tricyclazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tricyclazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0002405 a rdfs:Class ;
rdfs:label "immune system" ;
rdfs:comment "Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." ;
rdfs:subClassOf obo:UBERON_0015203 .
obo:PR_P55097 a rdfs:Class ;
rdfs:label "cathepsin K (mouse)" ;
rdfs:comment "A cathepsin K that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001850 , obo:PR_000029032 .
obo:CL_4033054 a rdfs:Class ;
rdfs:label "perivascular cell" ;
rdfs:comment "A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_1901203 a rdfs:Class ;
rdfs:label "positive regulation of extracellular matrix assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly." ;
rdfs:subClassOf obo:GO_0044089 , obo:GO_0065007 , obo:GO_1901201 , obo:GO_1903055 .
obo:UBERON_0002040 a rdfs:Class ;
rdfs:label "bronchial artery" ;
rdfs:comment "A systemic artery that supplies the lung with with oxygenated blood." ;
rdfs:subClassOf obo:UBERON_0004573 .
obo:PHIPO_0001284 a rdfs:Class ;
rdfs:label "decreased host protein phosphorylation with pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, during pathogen infection occurs to a lesser extent than normal (GO:0006468 protein phosphorylation)." ;
rdfs:subClassOf obo:PHIPO_0001247 .
obo:PHIPO_0000052 a rdfs:Class ;
rdfs:label "decreased number of asexual spores"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of asexual spores is decreased." ;
rdfs:subClassOf obo:PHIPO_0000082 .
obo:GO_0045905 a rdfs:Class ;
rdfs:label "positive regulation of translational termination" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translational termination." ;
rdfs:subClassOf obo:GO_0006449 , obo:GO_0043243 , obo:GO_0045727 , obo:GO_0065007 .
obo:PHIPO_0000131 a rdfs:Class ;
rdfs:label "pathogen host protein-protein interaction phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype which affects the binding of one pathogen protein to one host protein. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000164 .
obo:PHIPO_0000183 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host interaction DNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." .
obo:GO_0048588 a rdfs:Class ;
rdfs:label "developmental cell growth" ;
rdfs:comment "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." ;
rdfs:subClassOf obo:GO_0016049 , obo:GO_0048589 .
obo:GO_0032103 a rdfs:Class ;
rdfs:label "positive regulation of response to external stimulus" ;
rdfs:comment "Any process that activates, maintains or increases the rate of a response to an external stimulus." ;
rdfs:subClassOf obo:GO_0032101 , obo:GO_0048584 , obo:GO_0065007 .
obo:PHIPO_0000773 a rdfs:Class ;
rdfs:label "sensitive to nystatin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to nystatin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0097194 a rdfs:Class ;
rdfs:label "execution phase of apoptosis" ;
rdfs:comment "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0015631 a rdfs:Class ;
rdfs:label "tubulin binding" ;
rdfs:comment "Binding to monomeric or multimeric forms of tubulin, including microtubules." ;
rdfs:subClassOf obo:GO_0008092 .
obo:PR_Q9WTK5 a rdfs:Class ;
rdfs:label "nuclear factor NF-kappa-B p100 subunit (mouse)" ;
rdfs:comment "A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000011178 , obo:PR_000029032 .
obo:UBERON_0001096 a rdfs:Class ;
rdfs:label "wall of esophagus" ;
rdfs:comment "An anatomical wall that is part of a esophagus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0000328 .
obo:GO_0071375 a rdfs:Class ;
rdfs:label "cellular response to peptide hormone stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." ;
rdfs:subClassOf obo:GO_0032870 , obo:GO_0043434 , obo:GO_0070887 , obo:GO_1901699 , obo:GO_1901701 .
obo:GO_0003150 a rdfs:Class ;
rdfs:label "muscular septum morphogenesis" ;
rdfs:comment "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060415 .
obo:CL_0002010 a rdfs:Class ;
rdfs:label "pre-conventional dendritic cell" ;
rdfs:comment "A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha." ;
rdfs:subClassOf obo:CL_0000763 , obo:CL_0002031 .
obo:GO_0061919 a rdfs:Class ;
rdfs:label "process utilizing autophagic mechanism" ;
rdfs:comment "A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0051053 a rdfs:Class ;
rdfs:label "negative regulation of DNA metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." ;
rdfs:subClassOf obo:GO_0010605 , obo:GO_0045934 , obo:GO_0051052 , obo:GO_0065007 .
obo:PHIPO_0000886 a rdfs:Class ;
rdfs:label "sensitive to amoxicillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to amoxicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:CHEBI_22495 a rdfs:Class ;
rdfs:label "aminobenzoic acid" ;
rdfs:subClassOf obo:CHEBI_22723 , obo:CHEBI_33856 .
obo:GO_1902034 a rdfs:Class ;
rdfs:label "negative regulation of hematopoietic stem cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902033 , obo:GO_1903707 , obo:GO_2000647 .
obo:CHEBI_144644 a rdfs:Class ;
rdfs:label "a tetracycline zwitterion" ;
rdfs:subClassOf obo:CHEBI_26895 .
obo:CHEBI_33447 a rdfs:Class ;
rdfs:label "phospho sugar" ;
rdfs:comment "Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid." ;
rdfs:subClassOf obo:CHEBI_26816 , obo:CHEBI_63367 .
obo:PHIPO_0001314 a rdfs:Class ;
rdfs:label "sensitive to zoxamide"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to zoxamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0009141 a rdfs:Class ;
rdfs:label "craniocervical region vein" ;
rdfs:comment "A vein that is part of a craniocervical region." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0013140 .
obo:GO_0021517 a rdfs:Class ;
rdfs:label "ventral spinal cord development" ;
rdfs:comment "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_35296 a rdfs:Class ;
rdfs:label "ortho-fused polycyclic arene" ;
rdfs:subClassOf obo:CHEBI_33848 , obo:CHEBI_35427 .
obo:PR_000001444 a rdfs:Class ;
rdfs:label "cadherin-5" ;
rdfs:comment "A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001327 .
obo:GO_0042255 a rdfs:Class ;
rdfs:label "ribosome assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0140694 .
obo:CHEBI_84739 a rdfs:Class ;
rdfs:label "amikacin(4+)" ;
rdfs:comment "An organic cation obtained by protonation of the four free amino groups of amikacin; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_0003168 a rdfs:Class ;
rdfs:label "Purkinje myocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0060932 .
obo:PATO_0002301 a rdfs:Class ;
rdfs:label "decreased quality" ;
rdfs:comment "A quality that has a value that is decreased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0000001 , obo:PATO_0000069 .
obo:GO_0050775 a rdfs:Class ;
rdfs:label "positive regulation of dendrite morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis." ;
rdfs:subClassOf obo:GO_0010770 , obo:GO_0031346 , obo:GO_0048814 , obo:GO_0050769 , obo:GO_0065007 .
obo:PHIPO_0000447 a rdfs:Class ;
rdfs:label "increased number of asexual pathogen spores within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is increased." ;
rdfs:subClassOf obo:PHIPO_0000448 .
obo:CHEBI_38261 a rdfs:Class ;
rdfs:label "imidazolidines" ;
rdfs:subClassOf obo:CHEBI_38304 .
obo:CL_0019018 a rdfs:Class ;
rdfs:label "blood vessel smooth muscle cell"@en ;
rdfs:comment "A smooth muscle cell that is part of any blood vessel." ;
rdfs:subClassOf obo:CL_0000192 , obo:CL_0000359 .
obo:GO_0099177 a rdfs:Class ;
rdfs:label "regulation of trans-synaptic signaling" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0023051 , obo:GO_0065007 .
obo:PHIPO_0000167 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction RNA binding phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects RNA binding. The relevant gene product may be encoded by the mutated gene, or by a different gene." .
obo:GO_1903380 a rdfs:Class ;
rdfs:label "positive regulation of mitotic chromosome condensation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090068 , obo:GO_1903379 , obo:GO_1905821 .
obo:GO_0061888 a rdfs:Class ;
rdfs:label "regulation of astrocyte activation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of astrocyte activation." ;
rdfs:subClassOf obo:GO_0048710 , obo:GO_0050865 , obo:GO_0065007 .
obo:UBERON_0009581 a rdfs:Class ;
rdfs:label "midbrain mantle layer" ;
rdfs:subClassOf obo:UBERON_0004061 .
obo:PHIPO_0001192 a rdfs:Class ;
rdfs:label "decreased level of host defense-induced reactive oxygen species"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host produced reactive oxygen species (ROS), often associated with an oxidative burst response during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0000924 .
obo:UBERON_0007690 a rdfs:Class ;
rdfs:label "early pharyngeal endoderm" ;
rdfs:comment "relation conflict: ZFA vs EHDAA2. Note EHDAA2 term renamed to 'early PA endoderm'" ;
rdfs:subClassOf obo:UBERON_0003258 , obo:UBERON_0005291 .
obo:CHEBI_57305 a rdfs:Class .
obo:UBERON_0005953 a rdfs:Class ;
rdfs:label "outflow part of right ventricle" ;
rdfs:comment "Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk." ;
rdfs:subClassOf obo:UBERON_0005337 .
obo:UBERON_8440004 a rdfs:Class ;
rdfs:label "laminar subdivision of the cortex" ;
rdfs:comment "One or a subset of adjacent layers of the neocortex." ;
rdfs:subClassOf obo:UBERON_0011215 .
obo:CHEBI_26188 a rdfs:Class ;
rdfs:label "polyketide" ;
rdfs:comment "Natural and synthetic compounds containing alternating carbonyl and methylene groups ('β-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:PR_P21183 a rdfs:Class ;
rdfs:label "interleukin-5 receptor subunit alpha (mouse)" ;
rdfs:comment "An interleukin-5 receptor subunit alpha that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001867 , obo:PR_000029032 .
obo:GO_0046942 a rdfs:Class ;
rdfs:label "carboxylic acid transport" ;
rdfs:comment "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015711 , obo:GO_0015849 .
obo:GO_0070129 a rdfs:Class ;
rdfs:label "regulation of mitochondrial translation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0062125 , obo:GO_0065007 .
obo:GO_0005766 a rdfs:Class ;
rdfs:label "primary lysosome" ;
rdfs:comment "A lysosome before it has fused with a vesicle or vacuole." ;
rdfs:subClassOf obo:GO_0005764 .
obo:CL_0002159 a rdfs:Class ;
rdfs:label "general ecto-epithelial cell" ;
rdfs:comment "Epithelial cells derived from general body ectoderm and ectoderm placodes." ;
rdfs:subClassOf obo:CL_0002077 .
obo:GO_0043067 a rdfs:Class ;
rdfs:label "regulation of programmed cell death" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0051726 a rdfs:Class ;
rdfs:label "regulation of cell cycle" ;
rdfs:comment "Any process that modulates the rate or extent of progression through the cell cycle." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0046622 a rdfs:Class ;
rdfs:label "positive regulation of organ growth" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." ;
rdfs:subClassOf obo:GO_0046620 , obo:GO_0048639 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0000271 a rdfs:Class ;
rdfs:label "polysaccharide biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ;
rdfs:subClassOf obo:GO_0005976 , obo:GO_0009058 , obo:GO_0009059 , obo:GO_0016051 .
obo:PHIPO_0001303 a rdfs:Class ;
rdfs:label "sensitive to osmotic stress"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to an osmotic stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide." ;
rdfs:subClassOf obo:PHIPO_0001098 .
obo:CHEBI_36641 a rdfs:Class ;
rdfs:label "3aH-benzimidazole" ;
rdfs:subClassOf obo:CHEBI_36622 .
obo:CHEBI_48535 a rdfs:Class ;
rdfs:label "aryloxypyrimidine" ;
rdfs:subClassOf obo:CHEBI_35618 , obo:CHEBI_39447 .
obo:GO_0016057 a rdfs:Class ;
rdfs:label "regulation of membrane potential in photoreceptor cell" ;
rdfs:comment "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon." ;
rdfs:subClassOf obo:GO_0042391 .
obo:PHIPO_0000881 a rdfs:Class ;
rdfs:label "sensitive to lincomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to lincomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0097708 a rdfs:Class ;
rdfs:label "intracellular vesicle" ;
rdfs:comment "Any vesicle that is part of the intracellular region." ;
rdfs:subClassOf obo:GO_0031982 , obo:GO_0043231 .
obo:GO_0120222 a rdfs:Class ;
rdfs:label "regulation of blastocyst development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of blastocyst development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0033037 a rdfs:Class ;
rdfs:label "polysaccharide localization" ;
rdfs:comment "Any process in which a polysaccharide is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0033036 .
obo:GO_0021696 a rdfs:Class ;
rdfs:label "cerebellar cortex morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_8674 a rdfs:Class ;
rdfs:label "pyrimethanil" ;
rdfs:comment "A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6. A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control Botrytis cinerea throughout the winemaking process in grapes, must, fermenting must and wine." ;
rdfs:subClassOf obo:CHEBI_38338 , obo:CHEBI_50995 , obo:CHEBI_87208 .
obo:PHIPO_0000440 a rdfs:Class ;
rdfs:label "normal pathogen reproductive phenotype within host"@en ;
rdfs:comment "A pathogen host interaction phenotype where the pathogen reproductive process within the host is normal (indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000439 .
obo:UBERON_0009856 a rdfs:Class ;
rdfs:label "sac" ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:PHIPO_0000774 a rdfs:Class ;
rdfs:label "sensitive to vinclozolin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to vinclozolin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0001539 a rdfs:Class ;
rdfs:label "cilium or flagellum-dependent cell motility" ;
rdfs:comment "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella." ;
rdfs:subClassOf obo:GO_0048870 .
obo:UBERON_0000014 a rdfs:Class ;
rdfs:label "zone of skin" ;
rdfs:comment "Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis." ;
rdfs:subClassOf obo:UBERON_0010314 , obo:UBERON_0034944 .
obo:CHEBI_25697 a rdfs:Class ;
rdfs:label "organic cation" ;
rdfs:comment "Any organic ion with a net positive charge." ;
rdfs:subClassOf obo:CHEBI_25699 , obo:CHEBI_36916 .
obo:CHEBI_79091 a rdfs:Class ;
rdfs:label "EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor" ;
rdfs:comment "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24)." ;
rdfs:subClassOf obo:CHEBI_76812 .
obo:PHIPO_0000475 a rdfs:Class ;
rdfs:label "decreased size of lipid droplet"@en ;
rdfs:comment "A single organism phenotype observed in the vegetative growth phase of the life cycle in which the size of lipid droplets is decreased." ;
rdfs:subClassOf obo:PHIPO_0000036 .
obo:GO_0030849 a rdfs:Class ;
rdfs:label "autosome" ;
rdfs:comment "Any chromosome other than a sex chromosome." ;
rdfs:subClassOf obo:GO_0005694 .
obo:UBERON_8440015 a rdfs:Class ;
rdfs:label "noradrenergic cell groups" ;
rdfs:comment "Collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain the neurotransmitter norepinephrine (noradrenalin)." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:CHEBI_142513 a rdfs:Class ;
rdfs:label "oxime anion" ;
rdfs:comment "A organic ion resulting from the deprotonation of the hydroxy group of any oxime." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:GO_0060837 a rdfs:Class ;
rdfs:label "blood vessel endothelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0045446 .
obo:UBERON_0004702 a rdfs:Class ;
rdfs:label "respiratory system blood vessel endothelium" ;
rdfs:comment "A blood vessel endothelium that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0004638 , obo:UBERON_0004807 .
obo:GO_0051957 a rdfs:Class ;
rdfs:label "positive regulation of amino acid transport" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051954 , obo:GO_0051955 , obo:GO_0065007 .
obo:GO_0034305 a rdfs:Class ;
rdfs:label "regulation of asexual sporulation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis." ;
rdfs:subClassOf obo:GO_0043937 , obo:GO_0065007 , obo:GO_1903664 .
obo:GO_0005275 a rdfs:Class ;
rdfs:label "amine transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group." ;
rdfs:subClassOf obo:GO_0022857 .
obo:GO_0048741 a rdfs:Class ;
rdfs:label "skeletal muscle fiber development" ;
rdfs:comment "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." ;
rdfs:subClassOf obo:GO_0014904 , obo:GO_0048856 .
obo:CHEBI_23367 a rdfs:Class ;
rdfs:label "molecular entity" ;
rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ;
rdfs:subClassOf obo:CHEBI_24431 .
obo:NCBITaxon_7776 a rdfs:Class ;
rdfs:label "Gnathostomata " ;
rdfs:subClassOf obo:NCBITaxon_7742 .
obo:GO_0021690 a rdfs:Class ;
rdfs:label "cerebellar molecular layer maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:GO_0030856 a rdfs:Class ;
rdfs:label "regulation of epithelial cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 , obo:GO_2000026 .
obo:GO_0009895 a rdfs:Class ;
rdfs:label "negative regulation of catabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0009894 , obo:GO_0065007 .
obo:GO_1905213 a rdfs:Class ;
rdfs:label "negative regulation of mitotic chromosome condensation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0065007 , obo:GO_1902340 , obo:GO_1903379 .
obo:PHIPO_0000695 a rdfs:Class ;
rdfs:label "resistance to clarithromycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to clarithromycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0035239 a rdfs:Class ;
rdfs:label "tube morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CL_0008025 a rdfs:Class ;
rdfs:label "noradrenergic neuron" ;
rdfs:comment "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter." ;
rdfs:subClassOf obo:CL_0000459 , obo:CL_0000540 , obo:CL_4033050 .
obo:PHIPO_0001334 a rdfs:Class ;
rdfs:label "resistance to fluazinam"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fluazinam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0035112 a rdfs:Class ;
rdfs:label "genitalia morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0009653 , obo:GO_0009887 .
obo:CHEBI_26217 a rdfs:Class ;
rdfs:label "potassium molecular entity" ;
rdfs:subClassOf obo:CHEBI_33296 .
obo:CHEBI_33292 a rdfs:Class ;
rdfs:label "fuel" ;
rdfs:comment "An energy-rich substance that can be transformed with release of usable energy." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_2000136 a rdfs:Class ;
rdfs:label "regulation of cell proliferation involved in heart morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:PHIPO_0001404 a rdfs:Class ;
rdfs:label "normal growth on mandipropamid" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to mandipropamid (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_1904019 a rdfs:Class ;
rdfs:label "epithelial cell apoptotic process" ;
rdfs:comment "Any apoptotic process in an epithelial cell." ;
rdfs:subClassOf obo:GO_0006915 .
obo:GO_0051495 a rdfs:Class ;
rdfs:label "positive regulation of cytoskeleton organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0051493 , obo:GO_0065007 .
obo:GO_0032233 a rdfs:Class ;
rdfs:label "positive regulation of actin filament bundle assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." ;
rdfs:subClassOf obo:GO_0032231 , obo:GO_0044089 , obo:GO_0051495 , obo:GO_0065007 , obo:GO_1902905 .
obo:GO_0007030 a rdfs:Class ;
rdfs:label "Golgi organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0016043 .
obo:GO_0032507 a rdfs:Class ;
rdfs:label "maintenance of protein location in cell" ;
rdfs:comment "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0051651 .
obo:PR_000030035 a rdfs:Class ;
rdfs:label "G-protein coupled receptor" ;
rdfs:comment "A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0060379 a rdfs:Class ;
rdfs:label "cardiac muscle cell myoblast differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." ;
rdfs:subClassOf obo:GO_0010002 , obo:GO_0030154 , obo:GO_0045445 .
obo:CL_4310138 a rdfs:Class ;
rdfs:label "STRv D2 MSN nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron (Primate)" ;
rdfs:comment "A nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D2 MSN." ;
rdfs:subClassOf obo:CL_4030052 , obo:CL_4310059 .
obo:GO_0035051 a rdfs:Class ;
rdfs:label "cardiocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_2000109 a rdfs:Class ;
rdfs:label "regulation of macrophage apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of macrophage apoptotic process." ;
rdfs:subClassOf obo:GO_0033032 , obo:GO_0065007 , obo:GO_2000106 .
obo:GO_0034766 a rdfs:Class ;
rdfs:label "negative regulation of monoatomic ion transmembrane transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0034763 , obo:GO_0034765 , obo:GO_0043271 , obo:GO_0065007 .
a rdfs:Class ;
rdfs:label "Isocortex" ;
rdfs:subClassOf , obo:UBERON_0001950 .
obo:CHEBI_35992 a rdfs:Class ;
rdfs:label "penams" ;
rdfs:comment "Natural and synthetic antibiotics containing the 4-thia-1-azabicyclo[3.2.0]heptan-7-one structure, generally assumed to have the 5R configuration unless otherwise specified." ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_27933 , obo:CHEBI_38106 .
obo:GO_0003165 a rdfs:Class ;
rdfs:label "Purkinje myocyte development" ;
rdfs:comment "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." ;
rdfs:subClassOf obo:GO_0003229 , obo:GO_0048856 .
obo:GO_0030855 a rdfs:Class ;
rdfs:label "epithelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." ;
rdfs:subClassOf obo:GO_0030154 .
obo:CHEBI_48626 a rdfs:Class ;
rdfs:label "pyranoindolizinoquinoline" ;
rdfs:subClassOf obo:CHEBI_38101 , obo:CHEBI_38104 , obo:CHEBI_38164 .
obo:GO_0015851 a rdfs:Class ;
rdfs:label "nucleobase transport" ;
rdfs:comment "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0071705 .
obo:PHIPO_0000178 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction DNA binding phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects DNA binding. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:GO_0051098 a rdfs:Class ;
rdfs:label "regulation of binding" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:UBERON_0004060 a rdfs:Class ;
rdfs:label "neural tube ventricular layer" ;
rdfs:comment "The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium." ;
rdfs:subClassOf obo:UBERON_0005291 , obo:UBERON_0010371 , obo:UBERON_0034706 .
obo:GO_1902036 a rdfs:Class ;
rdfs:label "regulation of hematopoietic stem cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901532 , obo:GO_2000736 .
obo:GO_0050890 a rdfs:Class ;
rdfs:label "cognition" ;
rdfs:comment "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." ;
rdfs:subClassOf obo:GO_0050877 .
obo:GO_0002071 a rdfs:Class ;
rdfs:label "glandular epithelial cell maturation" ;
rdfs:comment "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." ;
rdfs:subClassOf obo:GO_0002069 , obo:GO_0021700 .
obo:GO_0006308 a rdfs:Class ;
rdfs:label "DNA catabolic process" ;
rdfs:comment "The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one." ;
rdfs:subClassOf obo:GO_0006259 , obo:GO_0009056 , obo:GO_0141188 .
obo:GO_0002052 a rdfs:Class ;
rdfs:label "positive regulation of neuroblast proliferation" ;
rdfs:comment "Any process that activates or increases the rate of neuroblast proliferation." ;
rdfs:subClassOf obo:GO_0050769 , obo:GO_0065007 , obo:GO_1902692 , obo:GO_2000179 .
obo:PHIPO_0000721 a rdfs:Class ;
rdfs:label "sensitive to ethionamide"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ethionamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_7731 a rdfs:Class ;
rdfs:label "ofloxacin" ;
rdfs:comment "A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_86324 , obo:CHEBI_87211 .
obo:CL_0002224 a rdfs:Class ;
rdfs:label "lens epithelial cell" ;
rdfs:comment "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." ;
rdfs:subClassOf obo:CL_0000075 , obo:CL_0002222 .
obo:GO_0060496 a rdfs:Class ;
rdfs:label "mesenchymal-epithelial cell signaling involved in lung development" ;
rdfs:comment "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung." ;
rdfs:subClassOf obo:GO_0060638 .
obo:GO_0050433 a rdfs:Class ;
rdfs:label "regulation of catecholamine secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines." ;
rdfs:subClassOf obo:GO_0051952 , obo:GO_0065007 , obo:GO_1903530 .
obo:CHEBI_16136 a rdfs:Class ;
rdfs:label "hydrogen sulfide" ;
rdfs:comment "A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen." ;
rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_33405 , obo:CHEBI_33535 , obo:CHEBI_37176 .
obo:CHEBI_24828 a rdfs:Class ;
rdfs:label "indoles" ;
rdfs:comment "Any compound containing an indole skeleton." ;
rdfs:subClassOf obo:CHEBI_22728 .
obo:GO_0050772 a rdfs:Class ;
rdfs:label "positive regulation of axonogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of axonogenesis." ;
rdfs:subClassOf obo:GO_0031346 , obo:GO_0050769 , obo:GO_0050770 , obo:GO_0065007 .
obo:UBERON_0005292 a rdfs:Class ;
rdfs:label "extraembryonic tissue" ;
rdfs:comment "Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:GO_0000302 a rdfs:Class ;
rdfs:label "response to reactive oxygen species" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." ;
rdfs:subClassOf obo:GO_0006979 , obo:GO_0050896 , obo:GO_1901700 .
obo:CL_0002521 a rdfs:Class ;
rdfs:label "subcutaneous adipocyte" ;
rdfs:comment "An adipocyte that is part of subcutaneous adipose tissue." ;
rdfs:subClassOf obo:CL_0000136 .
obo:CHEBI_59392 a rdfs:Class ;
rdfs:label "cephalexin(1-)" ;
rdfs:comment "The anion resulting from the removal of a proton from the carboxylic acid group of cephalexin." ;
rdfs:subClassOf obo:CHEBI_52440 .
obo:PHIPO_0000947 a rdfs:Class ;
rdfs:label "increased cellular reactive oxygen species level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0000945 , obo:PHIPO_0001036 .
obo:CHEBI_8309 a rdfs:Class ;
rdfs:label "polymyxin B1" ;
rdfs:subClassOf obo:CHEBI_59062 .
obo:CHEBI_62070 a rdfs:Class ;
rdfs:label "nalidixic acid anion" ;
rdfs:comment "A monocarboxylic acid anion that is the conjugate base of nalidixic acid; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:PATO_0002287 a rdfs:Class ;
rdfs:label "increased elasticity" ;
rdfs:comment "An elasticity which is relatively high." ;
rdfs:subClassOf obo:PATO_0001171 , obo:PATO_0002305 .
obo:PHIPO_0001107 a rdfs:Class ;
rdfs:label "absence of pathogen host protein-protein interaction"@en ;
rdfs:comment "A molecular function phenotype in which the binding of one pathogen protein to one host protein is absent." ;
rdfs:subClassOf obo:PHIPO_0000131 .
obo:GO_0010666 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle cell apoptotic process" ;
rdfs:comment "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." ;
rdfs:subClassOf obo:GO_0010663 , obo:GO_0010665 , obo:GO_0065007 .
obo:UBERON_0013757 a rdfs:Class ;
rdfs:label "capillary blood" ;
rdfs:comment "A blood that is part of a capillary." ;
rdfs:subClassOf obo:UBERON_0000178 .
obo:GO_2001015 a rdfs:Class ;
rdfs:label "negative regulation of skeletal muscle cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0065007 , obo:GO_2001014 .
obo:CL_0002087 a rdfs:Class ;
rdfs:label "nongranular leukocyte" ;
rdfs:comment "A leukocyte that lacks granules." ;
rdfs:subClassOf obo:CL_0000738 .
obo:UBERON_0016529 a rdfs:Class ;
rdfs:label "cortex of cerebral lobe" ;
rdfs:comment "Grey matter neocortex region of a lobe of the cerebral hemisphere." ;
rdfs:subClassOf obo:UBERON_0005401 .
obo:PHIPO_0001377 a rdfs:Class ;
rdfs:label "normal number of resting structures"@en ;
rdfs:comment "A single species phenotype where the number of resting structures is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001376 .
obo:GO_0060572 a rdfs:Class ;
rdfs:label "morphogenesis of an epithelial bud" ;
rdfs:comment "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060571 .
obo:CL_4023011 a rdfs:Class ;
rdfs:label "lamp5 GABAergic interneuron" ;
rdfs:comment "A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Lamp5." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_4023064 .
obo:GO_0061561 a rdfs:Class ;
rdfs:label "trigeminal ganglion formation" ;
rdfs:comment "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0048646 , obo:GO_0061560 .
obo:CL_0000737 a rdfs:Class ;
rdfs:label "striated muscle cell" ;
rdfs:comment "Muscle cell which has as its direct parts myofilaments organized into sarcomeres." ;
rdfs:subClassOf obo:CL_0000187 .
obo:GO_0050810 a rdfs:Class ;
rdfs:label "regulation of steroid biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ;
rdfs:subClassOf obo:GO_0019218 , obo:GO_0046890 , obo:GO_0065007 .
obo:GO_0071230 a rdfs:Class ;
rdfs:label "cellular response to amino acid stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." ;
rdfs:subClassOf obo:GO_0043200 , obo:GO_0070887 , obo:GO_0071229 .
obo:PHIPO_0000722 a rdfs:Class ;
rdfs:label "sensitive to rotenone"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to rotenone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000413 a rdfs:Class ;
rdfs:label "abnormal molecular function"@en ;
rdfs:comment "A phenotype in which a specific molecular function is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000411 .
obo:GO_1901717 a rdfs:Class ;
rdfs:label "positive regulation of GABA catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0045764 , obo:GO_0062013 , obo:GO_0065007 , obo:GO_1901715 .
obo:UBERON_0004764 a rdfs:Class ;
rdfs:label "intramembranous bone tissue" ;
rdfs:comment "Bone tissue that forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." ;
rdfs:subClassOf obo:UBERON_0002481 .
obo:UBERON_8000009 a rdfs:Class ;
rdfs:label "Purkinje fiber network" ;
rdfs:comment "A collection of Purkinje fibers that receives signals from the right and left bundle branches and innervates the ventricular cardiac muscle. The Purkinje fiber network creates synchronized contractions of the heart ventricles." ;
rdfs:subClassOf obo:UBERON_0010131 , obo:UBERON_0018649 .
obo:CL_0000138 a rdfs:Class ;
rdfs:label "chondrocyte" ;
rdfs:comment "A skeletogenic cell that secretes a specialized, avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell." ;
rdfs:subClassOf obo:CL_0000153 , obo:CL_0000667 , obo:CL_0007001 .
obo:GO_1990611 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translational initiation in response to stress" ;
rdfs:comment "Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0043558 , obo:GO_0065007 , obo:GO_1904688 , obo:GO_1990497 .
obo:CHEBI_64898 a rdfs:Class ;
rdfs:label "anionic amino-acid residue" ;
rdfs:comment "An amino-acid residue carrying an overall negative charge." ;
rdfs:subClassOf obo:CHEBI_64775 .
a rdfs:Class ;
rdfs:label "Median eminence" ;
rdfs:subClassOf , obo:UBERON_0002197 .
obo:UBERON_0003605 a rdfs:Class ;
rdfs:label "eye skin gland" ;
rdfs:comment "A skin gland that is part of a camera-type eye [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002419 , obo:UBERON_0004859 , obo:UBERON_0015152 .
obo:UBERON_0001806 a rdfs:Class ;
rdfs:label "sympathetic ganglion" ;
rdfs:comment "A ganglion of the sympathetic nervous system. Examples: paravertebral and the prevertebral ganglia, which include the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia." ;
rdfs:subClassOf obo:UBERON_0000045 , obo:UBERON_0001805 .
obo:GO_0051050 a rdfs:Class ;
rdfs:label "positive regulation of transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0051049 , obo:GO_0065007 .
obo:UBERON_0002506 a rdfs:Class ;
rdfs:label "iris epithelium" ;
rdfs:comment "An epithelium that is part of a iris [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0000488 , obo:UBERON_0015808 .
obo:PHIPO_0000901 a rdfs:Class ;
rdfs:label "sensitive to azithromycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to azithromycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0004025 a rdfs:Class ;
rdfs:label "lateral ganglionic eminence" ;
rdfs:comment "A distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the striatum; however, neocortex, thalamus, septum and olfactory bulb neurons are also partly derived from the LGE." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:PHIPO_0000094 a rdfs:Class ;
rdfs:label "obsolete normal mitosis in asexual reproduction" .
obo:GO_0014055 a rdfs:Class ;
rdfs:label "acetylcholine secretion, neurotransmission" ;
rdfs:comment "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)." ;
rdfs:subClassOf obo:GO_0007269 , obo:GO_0061526 .
obo:CHEBI_33893 a rdfs:Class ;
rdfs:label "reagent" ;
rdfs:comment "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:UBERON_0007247 a rdfs:Class ;
rdfs:label "nucleus of superior olivary complex" ;
rdfs:comment "Any of the nuclei that comprise the superior olivary complex (superior olive). This includes both the primary nuclei such as the lateral and medial nuclei, as well as periolivary nuclei." ;
rdfs:subClassOf obo:UBERON_0002308 , obo:UBERON_0006331 , obo:UBERON_0009662 .
obo:GO_1904745 a rdfs:Class ;
rdfs:label "Atg1/ULK1 kinase complex assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex." ;
rdfs:subClassOf obo:GO_0065003 .
obo:CL_0002009 a rdfs:Class ;
rdfs:label "macrophage dendritic cell progenitor" ;
rdfs:comment "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages." ;
rdfs:subClassOf obo:CL_0000763 , obo:CL_0002032 , obo:CL_0011026 .
obo:GO_1903976 a rdfs:Class ;
rdfs:label "negative regulation of glial cell migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration." ;
rdfs:subClassOf obo:GO_0030336 , obo:GO_0065007 , obo:GO_1903975 .
obo:GO_1905904 a rdfs:Class ;
rdfs:label "positive regulation of mesoderm formation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mesoderm formation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905902 , obo:GO_2000382 .
obo:PHIPO_0000851 a rdfs:Class ;
rdfs:label "sensitive to captan"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to captan. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000544 a rdfs:Class ;
rdfs:label "resistance to cycloheximide"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cycloheximide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_0000675 a rdfs:Class ;
rdfs:label "female gamete" ;
rdfs:comment "A mature sexual reproductive cell of the female germline." ;
rdfs:subClassOf obo:CL_0000021 , obo:CL_0000300 .
obo:CHEBI_36639 a rdfs:Class ;
rdfs:label "2H-benzimidazole" ;
rdfs:subClassOf obo:CHEBI_36622 .
obo:GO_0002614 a rdfs:Class ;
rdfs:label "negative regulation of monocyte antigen processing and presentation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002578 , obo:GO_0002613 , obo:GO_0065007 .
obo:CHEBI_229543 a rdfs:Class ;
rdfs:label "sulbactam(1-)" ;
rdfs:comment "A monocarboxylic acid anion that is the conjugate base of sulbactam resulting from the deprotonation of the carboxy group; Major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:CHEBI_167183 a rdfs:Class ;
rdfs:label "piscicide" ;
rdfs:comment "A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water." ;
rdfs:subClassOf obo:CHEBI_25944 .
obo:CL_0000150 a rdfs:Class ;
rdfs:label "glandular secretory epithelial cell" ;
rdfs:comment "An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0000151 , obo:CL_1100001 .
obo:CHEBI_50779 a rdfs:Class ;
rdfs:label "appetite enhancer" ;
rdfs:comment "A drug which increases appetite." ;
rdfs:subClassOf obo:CHEBI_50780 .
obo:GO_0048871 a rdfs:Class ;
rdfs:label "multicellular organismal-level homeostasis" ;
rdfs:comment "Any process involved in the maintenance of an internal steady state at the level of the multicellular organism." ;
rdfs:subClassOf obo:GO_0032501 , obo:GO_0042592 .
obo:CL_0000145 a rdfs:Class ;
rdfs:label "professional antigen presenting cell" ;
rdfs:comment "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." ;
rdfs:subClassOf obo:CL_0000738 .
obo:GO_0062197 a rdfs:Class ;
rdfs:label "cellular response to chemical stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0033554 , obo:GO_0070887 .
obo:PHIPO_0000091 a rdfs:Class ;
rdfs:label "obsolete abnormal budding" .
obo:PR_000007858 a rdfs:Class ;
rdfs:label "endothelial transcription factor GATA-2" ;
rdfs:comment "A protein that is a translation product of the human GATA2 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0051149 a rdfs:Class ;
rdfs:label "positive regulation of muscle cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0051147 , obo:GO_0065007 .
obo:CHEBI_25585 a rdfs:Class ;
rdfs:label "nonmetal atom" ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:PHIPO_0000103 a rdfs:Class ;
rdfs:label "obsolete gain of motility" .
obo:UBERON_0004465 a rdfs:Class ;
rdfs:label "musculature of neck" ;
rdfs:comment "Any collection of muscles that is part of a neck [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001015 .
obo:UBERON_0003616 a rdfs:Class ;
rdfs:label "bronchus elastic tissue" ;
rdfs:comment "An elastic tissue that is part of a bronchus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002521 , obo:UBERON_0003592 , obo:UBERON_0003611 .
obo:CHEBI_37670 a rdfs:Class ;
rdfs:label "protease inhibitor" ;
rdfs:comment "A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases)." ;
rdfs:subClassOf obo:CHEBI_60258 .
obo:CL_4307097 a rdfs:Class ;
rdfs:label "COP NN_1 Cck committed oligodendrocyte precursor (Mmus)" ;
rdfs:comment "A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Bmp4 (Mmus), Cck (Mmus), Ptger1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Bmp4, Cck, Ptger1. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5277 COP NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301611 .
obo:CHEBI_28963 a rdfs:Class ;
rdfs:label "amino sugar" ;
rdfs:comment "Any sugar having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups." ;
rdfs:subClassOf obo:CHEBI_63299 .
obo:CHEBI_33302 a rdfs:Class ;
rdfs:label "pnictogen molecular entity" ;
rdfs:comment "A p-block molecular entity containing any pnictogen." ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:PHIPO_0000785 a rdfs:Class ;
rdfs:label "sensitive to sulfanilamide"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulfanilamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_36830 a rdfs:Class ;
rdfs:label "monoanion" ;
rdfs:subClassOf obo:CHEBI_22563 .
obo:GO_0050932 a rdfs:Class ;
rdfs:label "regulation of pigment cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of pigmented cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:UBERON_0004274 a rdfs:Class ;
rdfs:label "lateral ventricle choroid plexus epithelium" ;
rdfs:comment "A choroid plexus epithelium that is part of a lateral ventricle [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003911 .
obo:UBERON_0012314 a rdfs:Class ;
rdfs:label "embryonic facial prominence" ;
rdfs:comment "One of five swellings formed during the development of the face." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0008134 a rdfs:Class ;
rdfs:label "transcription factor binding" ;
rdfs:comment "Binding to a transcription factor, a protein required to initiate or regulate transcription." ;
rdfs:subClassOf obo:GO_0005515 .
obo:CL_0000031 a rdfs:Class ;
rdfs:label "neuroblast (sensu Vertebrata)" ;
rdfs:comment "A cell that will develop into a neuron often after a migration phase." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0011026 .
obo:CHEBI_17843 a rdfs:Class .
obo:GO_0009070 a rdfs:Class ;
rdfs:label "serine family amino acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of an amino acid derived from 3-phosphoglycerate (L-serine, glycine, L-cysteine and L-homocysteine)." ;
rdfs:subClassOf obo:GO_0008652 , obo:GO_0009058 , obo:GO_0046394 .
obo:UBERON_0009657 a rdfs:Class ;
rdfs:label "artery of lip" ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:GO_2000198 a rdfs:Class ;
rdfs:label "negative regulation of ribonucleoprotein complex localization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0065007 , obo:GO_2000197 .
obo:GO_0042277 a rdfs:Class ;
rdfs:label "peptide binding" ;
rdfs:comment "Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds." ;
rdfs:subClassOf obo:GO_0005488 .
obo:GO_0043536 a rdfs:Class ;
rdfs:label "positive regulation of blood vessel endothelial cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels." ;
rdfs:subClassOf obo:GO_0010595 , obo:GO_0043535 , obo:GO_0065007 .
obo:GO_0002063 a rdfs:Class ;
rdfs:label "chondrocyte development" ;
rdfs:comment "The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:PHIPO_0001233 a rdfs:Class ;
rdfs:label "pathogen inhibition of host defense induced acidification in phagolysome"@en ;
rdfs:comment "A pathogen host interaction phenotype where the host induced pH decrease within the host phagolysome in response to pathogen colonization is inhibited." ;
rdfs:subClassOf obo:PHIPO_0001108 .
obo:GO_0048243 a rdfs:Class ;
rdfs:label "norepinephrine secretion" ;
rdfs:comment "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system." ;
rdfs:subClassOf obo:GO_0023061 , obo:GO_0046903 , obo:GO_0050432 .
obo:PHIPO_0000673 a rdfs:Class ;
rdfs:label "resistance to thiabendazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to thiabendazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0061195 a rdfs:Class ;
rdfs:label "taste bud formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CL_0000765 a rdfs:Class ;
rdfs:label "erythroblast" ;
rdfs:comment "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." ;
rdfs:subClassOf obo:CL_0000764 , obo:CL_0011026 .
obo:GO_0050790 a rdfs:Class ;
rdfs:label "regulation of catalytic activity" ;
rdfs:comment "Any process that modulates the activity of an enzyme." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:GO_0032272 a rdfs:Class ;
rdfs:label "negative regulation of protein polymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." ;
rdfs:subClassOf obo:GO_0031333 , obo:GO_0032271 , obo:GO_0065007 .
obo:GO_0060221 a rdfs:Class ;
rdfs:label "retinal rod cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0060219 .
obo:UBERON_0000923 a rdfs:Class ;
rdfs:label "germ layer" ;
rdfs:comment "A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm." ;
rdfs:subClassOf obo:UBERON_0010316 .
obo:PHIPO_0001308 a rdfs:Class ;
rdfs:label "normal growth on chemical"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to a specific chemical (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001218 .
obo:GO_0005976 a rdfs:Class ;
rdfs:label "polysaccharide metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ;
rdfs:subClassOf obo:GO_0005975 , obo:GO_0008152 , obo:GO_0043170 .
obo:UBERON_0003119 a rdfs:Class ;
rdfs:label "pharyngeal arch artery 2" ;
rdfs:comment "The vessels formed within the second pair of branchial arches in embryogenesis." ;
rdfs:subClassOf obo:UBERON_0004363 .
obo:GO_0002244 a rdfs:Class ;
rdfs:label "hematopoietic progenitor cell differentiation" ;
rdfs:comment "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0050921 a rdfs:Class ;
rdfs:label "positive regulation of chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ;
rdfs:subClassOf obo:GO_0032103 , obo:GO_0040017 , obo:GO_0050920 , obo:GO_0065007 .
a rdfs:Class ;
rdfs:label "SST" ;
rdfs:subClassOf obo:SO_0000704 .
obo:UBERON_0035767 a rdfs:Class ;
rdfs:label "intrapulmonary bronchus" ;
rdfs:subClassOf obo:UBERON_0002185 .
obo:CL_4307027 a rdfs:Class ;
rdfs:label "cerebellar astrocyte (Mmus)" ;
rdfs:comment "A transcriptomically defined type of astrocyte localized exclusively in the cerebellum beneath the Purkinje cell layer. It is distinguished from other cells in the brain by selective expression of Dao (Mmus), Efemp1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5207 Astro-CB NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0002603 .
obo:GO_0045598 a rdfs:Class ;
rdfs:label "regulation of fat cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of adipocyte differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:PHIPO_0000749 a rdfs:Class ;
rdfs:label "sensitive to bleomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to bleomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0150105 a rdfs:Class ;
rdfs:label "protein localization to cell-cell junction" ;
rdfs:comment "A process in which a protein is transported to, or maintained, in a location within a cell-cell junction." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_1902414 .
obo:UBERON_0001801 a rdfs:Class ;
rdfs:label "anterior segment of eyeball" ;
rdfs:comment "Any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive)." ;
rdfs:subClassOf obo:UBERON_0000063 .
obo:CHEBI_140922 a rdfs:Class ;
rdfs:label "glioma-associated oncogene inhibitor" ;
rdfs:comment "An inhibitor of any of the glioma-associated oncogene (GLI) proteins." ;
rdfs:subClassOf obo:CHEBI_35222 .
obo:CL_4310118 a rdfs:Class ;
rdfs:label "STH PVALB-PITX2 Glut glutamatergic neuron of the basal ganglia (Primate)" ;
rdfs:comment "A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the subthalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STH PVALB-PITX2 Glut." ;
rdfs:subClassOf obo:CL_0000700 , obo:CL_4042040 .
obo:CHEBI_58214 a rdfs:Class ;
rdfs:label "kanamycin A(4+)" ;
rdfs:comment "A quadruply-charged organic cation arising from protonation of the four amino groups of kanamycin A; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 .
obo:GO_1902817 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to microtubule" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902816 , obo:GO_1903828 .
obo:CHEBI_59999 a rdfs:Class ;
rdfs:label "chemical substance" ;
rdfs:comment "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." ;
rdfs:subClassOf obo:CHEBI_24431 .
obo:GO_0035987 a rdfs:Class ;
rdfs:label "endodermal cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo." ;
rdfs:subClassOf obo:GO_0030154 .
obo:UBERON_0010708 a rdfs:Class ;
rdfs:label "pectoral complex" ;
rdfs:comment "Appendage girdle complex that when present, encompasses the pectoral appendicular skeleton and the pectoral girdle." ;
rdfs:subClassOf obo:UBERON_0010707 .
obo:GO_0002520 a rdfs:Class ;
rdfs:label "immune system development" ;
rdfs:comment "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0048731 , obo:GO_0048856 .
obo:UBERON_0005162 a rdfs:Class ;
rdfs:label "multi cell part structure" ;
rdfs:comment "A structure consisting mainly of cell components, rather than complete cells." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0048518 a rdfs:Class ;
rdfs:label "positive regulation of biological process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:CHEBI_47622 a rdfs:Class .
obo:GO_0040015 a rdfs:Class ;
rdfs:label "negative regulation of multicellular organism growth" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size." ;
rdfs:subClassOf obo:GO_0040014 , obo:GO_0048640 , obo:GO_0051241 , obo:GO_0065007 .
obo:GO_0019614 a rdfs:Class ;
rdfs:label "catechol-containing compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0009712 , obo:GO_0019336 .
obo:PHIPO_0000060 a rdfs:Class ;
rdfs:label "obsolete normal timing in production of asexual spores" .
obo:GO_0060561 a rdfs:Class ;
rdfs:label "apoptotic process involved in morphogenesis" ;
rdfs:comment "Any apoptotic process that contributes to the shaping of an anatomical structure." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_1902742 .
obo:GO_0061304 a rdfs:Class ;
rdfs:label "retinal blood vessel morphogenesis" ;
rdfs:comment "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048514 , obo:GO_0061299 .
obo:UBERON_0002342 a rdfs:Class ;
rdfs:label "neural crest" ;
rdfs:comment "A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]." ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0010316 .
obo:CL_0017504 a rdfs:Class ;
rdfs:label "polychromatophilic cytoplasm" ;
rdfs:comment "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions." ;
rdfs:subClassOf obo:GO_0005737 .
obo:PHIPO_0001009 a rdfs:Class ;
rdfs:label "abnormal vesicle-mediated transport during vegetative growth"@en ;
rdfs:comment "A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000257 .
obo:CHEBI_24839 a rdfs:Class ;
rdfs:label "inorganic salt" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_24866 .
obo:PHIPO_0001168 a rdfs:Class ;
rdfs:label "presence of pathogen inhibition of host immune response protease"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the host immune response protease activity is inhibited by the pathogen." ;
rdfs:subClassOf obo:PHIPO_0001167 .
obo:GO_0022612 a rdfs:Class ;
rdfs:label "gland morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a gland are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:GO_0051248 a rdfs:Class ;
rdfs:label "negative regulation of protein metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." ;
rdfs:subClassOf obo:GO_0010605 , obo:GO_0051246 , obo:GO_0065007 .
obo:GO_1901880 a rdfs:Class ;
rdfs:label "negative regulation of protein depolymerization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." ;
rdfs:subClassOf obo:GO_0043242 , obo:GO_0065007 , obo:GO_1901879 .
obo:CHEBI_19834 a rdfs:Class ;
rdfs:label "3',5'-cyclic purine nucleotide" ;
rdfs:subClassOf obo:CHEBI_18375 , obo:CHEBI_36982 .
obo:GO_0010616 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle adaptation" ;
rdfs:comment "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." ;
rdfs:subClassOf obo:GO_0010612 , obo:GO_0014745 , obo:GO_0065007 .
obo:PR_P35461 a rdfs:Class ;
rdfs:label "lymphocyte antigen 6G (mouse)" ;
rdfs:comment "A lymphocyte antigen 6G that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000002978 , obo:PR_000029032 .
obo:GO_0002626 a rdfs:Class ;
rdfs:label "negative regulation of T cell antigen processing and presentation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002578 , obo:GO_0002625 , obo:GO_0002710 , obo:GO_0065007 .
obo:GO_0048568 a rdfs:Class ;
rdfs:label "embryonic organ development" ;
rdfs:comment "Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:PHIPO_0000071 a rdfs:Class ;
rdfs:label "abnormal sexual spore size"@en ;
rdfs:comment "A reproductive morphology phenotype where the size of the sexual spore is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000130 .
obo:PHIPO_0001325 a rdfs:Class ;
rdfs:label "normal growth on tebuconazole"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to tebuconazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0090091 a rdfs:Class ;
rdfs:label "positive regulation of extracellular matrix disassembly" ;
rdfs:comment "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." ;
rdfs:subClassOf obo:GO_0010715 , obo:GO_0065007 , obo:GO_1903055 .
obo:PHIPO_0000521 a rdfs:Class ;
rdfs:label "resistance to boscalid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to boscalid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_46845 a rdfs:Class ;
rdfs:label "N-alkylpiperazine" ;
rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_50996 .
obo:GO_1990863 a rdfs:Class ;
rdfs:label "acinar cell proliferation" ;
rdfs:comment "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0050673 .
obo:UBERON_0001675 a rdfs:Class ;
rdfs:label "trigeminal ganglion" ;
rdfs:comment "The cranial ganglion that is associated with and extends fibers into the trigeminal nerve." ;
rdfs:subClassOf obo:UBERON_0001714 , obo:UBERON_0001800 , obo:UBERON_0004121 .
obo:UBERON_0001610 a rdfs:Class ;
rdfs:label "lingual artery" ;
rdfs:comment "The lingual artery arises from the external carotid between the superior thyroid and facial artery[WP]." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0015212 , obo:UBERON_0035398 .
obo:PHIPO_0001444 a rdfs:Class ;
rdfs:label "sensitive to heat stress" ;
rdfs:comment "a cell phenotype in which cells grow to a lower extent than wild type following exposure to heat." ;
rdfs:subClassOf obo:PHIPO_0001098 .
obo:PHIPO_0000733 a rdfs:Class ;
rdfs:label "sensitive to cefaclor"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefaclor. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000789 a rdfs:Class ;
rdfs:label "sensitive to telithromycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to telithromycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0014807 a rdfs:Class ;
rdfs:label "regulation of somitogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of somitogenesis." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0051239 , obo:GO_0065007 .
obo:CHEBI_35274 a rdfs:Class ;
rdfs:label "ammonium ion derivative" ;
rdfs:comment "A derivative of ammonium, NH4+, in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." ;
rdfs:subClassOf obo:CHEBI_33702 , obo:CHEBI_51143 .
obo:PHIPO_0000493 a rdfs:Class ;
rdfs:label "primary metabolic process phenotype"@en ;
rdfs:comment "A single organism phenotype that affects the chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ;
rdfs:subClassOf obo:PHIPO_0000492 .
obo:UBERON_0004572 a rdfs:Class ;
rdfs:label "arterial system" ;
rdfs:comment "The part of the cardiovascular system consisting of all arteries." ;
rdfs:subClassOf obo:UBERON_0007798 .
obo:GO_0062014 a rdfs:Class ;
rdfs:label "negative regulation of small molecule metabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0062012 , obo:GO_0065007 .
obo:GO_1903524 a rdfs:Class ;
rdfs:label "positive regulation of blood circulation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of blood circulation." ;
rdfs:subClassOf obo:GO_0051240 , obo:GO_0065007 , obo:GO_1903522 .
obo:GO_0099170 a rdfs:Class ;
rdfs:label "postsynaptic modulation of chemical synaptic transmission" ;
rdfs:comment "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission." ;
rdfs:subClassOf obo:GO_0050804 .
obo:CHEBI_18257 a rdfs:Class ;
rdfs:label "ornithine" ;
rdfs:comment "An α-amino acid that is pentanoic acid bearing two amino substituents at positions 2 and 5." ;
rdfs:subClassOf obo:CHEBI_83925 .
obo:CHEBI_32161 a rdfs:Class ;
rdfs:label "sulfadimethoxine" ;
rdfs:comment "A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position." ;
rdfs:subClassOf obo:CHEBI_35618 , obo:CHEBI_39447 , obo:CHEBI_48975 , obo:CHEBI_87228 .
obo:GO_0019748 a rdfs:Class ;
rdfs:label "secondary metabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." ;
rdfs:subClassOf obo:GO_0008152 .
obo:UBERON_0000379 a rdfs:Class ;
rdfs:label "tracheal mucosa" ;
rdfs:comment "A mucosa that is part of a trachea." ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0004785 .
obo:PHIPO_0000022 a rdfs:Class ;
rdfs:label "increased resistance to chemical" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to a specific chemical. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0001218 .
obo:UBERON_0009505 a rdfs:Class ;
rdfs:label "mesenchyme of trachea" ;
rdfs:comment "Mesenchyme that is part of a developing trachea." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0007524 .
obo:UBERON_0004161 a rdfs:Class ;
rdfs:label "septum transversum" ;
rdfs:comment "A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]." ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:CHEBI_35496 a rdfs:Class ;
rdfs:label "fluorobenzenes" ;
rdfs:comment "Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_37143 .
obo:CL_4300102 a rdfs:Class ;
rdfs:label "STR D2 Gaba indirect pathway medium spiny neuron (Mmus)" ;
rdfs:comment "A indirect pathway medium spiny neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Adora2a (Mmus), Phactr1 (Mmus), Pcp4l1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:062 STR D2 Gaba." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4023029 .
obo:CHEBI_50683 a rdfs:Class ;
rdfs:label "EC 1.5.1.3 (dihydrofolate reductase) inhibitor" ;
rdfs:comment "An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3)." ;
rdfs:subClassOf obo:CHEBI_73913 , obo:CHEBI_76863 .
obo:UBERON_0000019 a rdfs:Class ;
rdfs:label "camera-type eye" ;
rdfs:comment "An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid." ;
rdfs:subClassOf obo:UBERON_0000047 , obo:UBERON_0004121 , obo:UBERON_0010314 , obo:UBERON_0015212 .
obo:CHEBI_76870 a rdfs:Class ;
rdfs:label "EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor" ;
rdfs:comment "An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*)." ;
rdfs:subClassOf obo:CHEBI_76736 .
obo:GO_0005798 a rdfs:Class ;
rdfs:label "Golgi-associated vesicle" ;
rdfs:comment "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell." ;
rdfs:subClassOf obo:GO_0031410 .
obo:GO_0010639 a rdfs:Class ;
rdfs:label "negative regulation of organelle organization" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0051129 , obo:GO_0065007 .
obo:GO_0062237 a rdfs:Class ;
rdfs:label "protein localization to postsynapse" ;
rdfs:comment "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0035418 .
obo:GO_0043525 a rdfs:Class ;
rdfs:label "positive regulation of neuron apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0043523 , obo:GO_0065007 .
obo:UBERON_0006603 a rdfs:Class ;
rdfs:label "presumptive mesoderm" ;
rdfs:comment "Presumptive structure of the blastula that will develop into mesoderm." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_0046717 a rdfs:Class ;
rdfs:label "acid secretion" ;
rdfs:comment "The controlled release of acid by a cell or a tissue." ;
rdfs:subClassOf obo:GO_0046903 .
obo:CL_4307115 a rdfs:Class ;
rdfs:label "ABC NN_1 Cubn arachnoid barrier cell (Mmus)" ;
rdfs:comment "A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prg4 (Mmus), Cubn (Mmus). It is distinguished from other ABC NN cells by expression of Cubn. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5295 ABC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301616 .
obo:GO_0002823 a rdfs:Class ;
rdfs:label "negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." ;
rdfs:subClassOf obo:GO_0002820 , obo:GO_0002822 , obo:GO_0065007 .
obo:CHEBI_33598 a rdfs:Class ;
rdfs:label "carbocyclic compound" ;
rdfs:comment "A homocyclic compound in which all of the ring members are carbon atoms." ;
rdfs:subClassOf obo:CHEBI_33597 , obo:CHEBI_33832 .
obo:PATO_0002462 a rdfs:Class ;
rdfs:label "collagenous" ;
rdfs:comment "A composition quality inhering in an bearer by virtue of the bearer's consisting of collagen." ;
rdfs:subClassOf obo:PATO_0000025 .
obo:GO_0021815 a rdfs:Class ;
rdfs:label "modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration" ;
rdfs:comment "Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration." ;
rdfs:subClassOf obo:GO_0000226 .
a rdfs:Class ;
rdfs:label "Locus ceruleus" ;
rdfs:subClassOf , obo:UBERON_0002148 .
obo:PHIPO_0000574 a rdfs:Class ;
rdfs:label "resistance to pyrazinecarboxamide"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to pyrazinecarboxamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0140247 a rdfs:Class ;
rdfs:label "protein catabolic process at presynapse" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0140246 .
obo:CL_4307086 a rdfs:Class ;
rdfs:label "OPC NN_1 Neil3 oligodendrocyte precursor cell (Mmus)" ;
rdfs:comment "A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Pclaf (Mmus), Mki67 (Mmus), Foxg1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Neil3, Foxg1. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5266 OPC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300366 .
obo:GO_1905141 a rdfs:Class ;
rdfs:label "negative regulation of apical ectodermal ridge formation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1905140 .
obo:CL_0002202 a rdfs:Class ;
rdfs:label "epithelial cell of tracheobronchial tree" ;
rdfs:comment "An epithelial cell of the tracheobronchial tree." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002632 .
obo:GO_0090277 a rdfs:Class ;
rdfs:label "positive regulation of peptide hormone secretion" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." ;
rdfs:subClassOf obo:GO_0002793 , obo:GO_0046887 , obo:GO_0065007 , obo:GO_0090276 .
obo:UBERON_0005805 a rdfs:Class ;
rdfs:label "dorsal aorta" ;
rdfs:comment "The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." ;
rdfs:subClassOf obo:UBERON_0000947 , obo:UBERON_0003513 , obo:UBERON_0004120 .
obo:UBERON_0001456 a rdfs:Class ;
rdfs:label "face" ;
rdfs:comment "A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc)." ;
rdfs:subClassOf obo:UBERON_0001444 .
obo:UBERON_0000094 a rdfs:Class ;
rdfs:label "membrane organ" ;
rdfs:comment "Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:GO_0000741 a rdfs:Class ;
rdfs:label "karyogamy" ;
rdfs:comment "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei." ;
rdfs:subClassOf obo:GO_0006997 , obo:GO_0048284 .
obo:GO_0003407 a rdfs:Class ;
rdfs:label "neural retina development" ;
rdfs:comment "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0007269 a rdfs:Class ;
rdfs:label "pectoral appendage musculature" ;
rdfs:comment "Any collection of muscles that is part of a pectoral appendage." ;
rdfs:subClassOf obo:UBERON_0001015 , obo:UBERON_0007271 , obo:UBERON_0014793 .
obo:GO_1904351 a rdfs:Class ;
rdfs:label "negative regulation of protein catabolic process in the vacuole" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole." ;
rdfs:subClassOf obo:GO_0042177 , obo:GO_0065007 , obo:GO_1904350 .
obo:CHEBI_29101 a rdfs:Class ;
rdfs:label "sodium(1+)" ;
rdfs:comment "A monoatomic monocation obtained from sodium." ;
rdfs:subClassOf obo:CHEBI_25414 , obo:CHEBI_33504 , obo:CHEBI_37246 , obo:CHEBI_60242 .
obo:PHIPO_0001125 a rdfs:Class ;
rdfs:label "decreased growth on oleic acid carbon source"@en ;
rdfs:comment "A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing oleic acid as the carbon source." ;
rdfs:subClassOf obo:PHIPO_0001216 .
obo:GO_0072674 a rdfs:Class ;
rdfs:label "multinuclear osteoclast differentiation" ;
rdfs:comment "The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030316 .
obo:PHIPO_0000217 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction primary metabolic process phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." .
obo:GO_1904075 a rdfs:Class ;
rdfs:label "positive regulation of trophectodermal cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0065007 , obo:GO_1904073 .
obo:CHEBI_62643 a rdfs:Class ;
rdfs:label "anionic phospholipid" ;
rdfs:comment "Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1−), phosphatidate(2−), phosphatidylglycerol(1−)." ;
rdfs:subClassOf obo:CHEBI_58945 .
obo:CHEBI_50299 a rdfs:Class ;
rdfs:label "canonical ribonucleotide residue" ;
rdfs:subClassOf obo:CHEBI_50297 .
obo:GO_2000239 a rdfs:Class ;
rdfs:label "negative regulation of tRNA export from nucleus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus." ;
rdfs:subClassOf obo:GO_0046832 , obo:GO_0065007 , obo:GO_2000198 , obo:GO_2000238 .
obo:GO_0003143 a rdfs:Class ;
rdfs:label "embryonic heart tube morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048598 , obo:GO_0060562 .
obo:CHEBI_32871 a rdfs:Class ;
rdfs:label "prolinate" ;
rdfs:comment "An α-amino-acid anion that is the conjugate base of proline, arising from deprotonation of the carboxy group." ;
rdfs:subClassOf obo:CHEBI_33558 .
obo:GO_0021988 a rdfs:Class ;
rdfs:label "olfactory lobe development" ;
rdfs:comment "The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_38217 a rdfs:Class ;
rdfs:label "3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid)" ;
rdfs:subClassOf obo:CHEBI_36336 .
obo:GO_0048319 a rdfs:Class ;
rdfs:label "axial mesoderm morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the axial mesoderm are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048332 .
obo:CHEBI_35195 a rdfs:Class ;
rdfs:label "surfactant" ;
rdfs:comment "A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces." ;
rdfs:subClassOf obo:CHEBI_63046 .
obo:GO_0090317 a rdfs:Class ;
rdfs:label "negative regulation of intracellular protein transport" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0033157 , obo:GO_0051224 , obo:GO_0065007 .
obo:GO_0150077 a rdfs:Class ;
rdfs:label "regulation of neuroinflammatory response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuroinflammatory response." ;
rdfs:subClassOf obo:GO_0050727 , obo:GO_0065007 .
obo:GO_0071673 a rdfs:Class ;
rdfs:label "positive regulation of smooth muscle cell chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis." ;
rdfs:subClassOf obo:GO_0014911 , obo:GO_0050921 , obo:GO_0065007 , obo:GO_0071671 .
obo:CHEBI_136651 a rdfs:Class ;
rdfs:label "S100 calcium-binding protein B inhibitor" ;
rdfs:comment "Any inhibitor of S100 calcium-binding protein B." ;
rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 .
obo:UBERON_0003601 a rdfs:Class ;
rdfs:label "neck cartilage" ;
rdfs:comment "A cartilage that is part of a neck [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0007844 .
obo:GO_0098978 a rdfs:Class ;
rdfs:label "glutamatergic synapse" ;
rdfs:comment "A synapse that uses glutamate as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0045202 .
obo:GO_0015812 a rdfs:Class ;
rdfs:label "gamma-aminobutyric acid transport" ;
rdfs:comment "The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0006865 , obo:GO_0046942 , obo:GO_0071705 .
obo:GO_0019750 a rdfs:Class ;
rdfs:label "chloroplast localization" ;
rdfs:comment "Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051644 .
obo:GO_0033366 a rdfs:Class ;
rdfs:label "protein localization to secretory granule" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a secretory granule." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033365 .
obo:UBERON_0005764 a rdfs:Class ;
rdfs:label "acellular membrane" ;
rdfs:comment "An acellular anatomical structure that is the bounding layer of a anatomical structure." ;
rdfs:subClassOf obo:UBERON_0000476 .
obo:CHEBI_29985 a rdfs:Class .
obo:GO_1901624 a rdfs:Class ;
rdfs:label "negative regulation of lymphocyte chemotaxis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0002689 , obo:GO_0065007 , obo:GO_1901623 , obo:GO_2000402 .
obo:GO_0017148 a rdfs:Class ;
rdfs:label "negative regulation of translation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0010629 , obo:GO_0051248 , obo:GO_0065007 .
obo:GO_0015144 a rdfs:Class ;
rdfs:label "carbohydrate transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of carbohydrate from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 .
obo:GO_0047497 a rdfs:Class ;
rdfs:label "mitochondrion transport along microtubule" ;
rdfs:comment "The directed movement of a mitochondrion along a microtubule, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0034643 , obo:GO_0072384 .
obo:GO_0045621 a rdfs:Class ;
rdfs:label "positive regulation of lymphocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." ;
rdfs:subClassOf obo:GO_0045619 , obo:GO_0051251 , obo:GO_0065007 , obo:GO_1902107 .
obo:CHEBI_37826 a rdfs:Class ;
rdfs:label "sulfuric acid derivative" ;
rdfs:subClassOf obo:CHEBI_33424 .
obo:CL_2000013 a rdfs:Class ;
rdfs:label "fibroblast of skin of abdomen" ;
rdfs:comment "Any skin fibroblast that is part of a skin of abdomen." ;
rdfs:subClassOf obo:CL_0002620 .
obo:CL_4301598 a rdfs:Class ;
rdfs:label "Astro-OLF NN_3 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ednrb (Mmus), Hs3st3a1 (Mmus), C230072F16Rik (Mmus), Gria2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1168 Astro-OLF NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300360 .
a rdfs:Class ;
rdfs:label "Striatum dorsal region" ;
rdfs:subClassOf , obo:UBERON_0005382 .
obo:GO_1905330 a rdfs:Class ;
rdfs:label "regulation of morphogenesis of an epithelium" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0065007 .
obo:UBERON_0000170 a rdfs:Class ;
rdfs:label "pair of lungs" ;
rdfs:comment "The pair of anatomical structures comprised of a left lung and right lung." ;
rdfs:subClassOf obo:UBERON_0034925 .
obo:NCBITaxon_6656 a rdfs:Class ;
rdfs:label "Arthropoda" ;
rdfs:subClassOf obo:NCBITaxon_88770 .
obo:PHIPO_0000431 a rdfs:Class ;
rdfs:label "abolished pathogen chitin fragment binding"@en ;
rdfs:comment "A single species pathogen molecular function phenotype in which pathogen chitin fragment binding by a pathogen gene product does not occur. (It was present and is now absent)." ;
rdfs:subClassOf obo:PHIPO_0000421 .
obo:CL_0000218 a rdfs:Class ;
rdfs:label "myelinating Schwann cell" ;
rdfs:comment "A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons." ;
rdfs:subClassOf obo:CL_0002573 , obo:CL_4023154 .
obo:GO_0002233 a rdfs:Class ;
rdfs:label "leukocyte chemotaxis involved in immune response" ;
rdfs:comment "The movement of an immune cell in response to an external stimulus a part of an immune response." ;
rdfs:subClassOf obo:GO_0002522 , obo:GO_0030595 .
obo:UBERON_0009198 a rdfs:Class ;
rdfs:label "craniofacial suture" ;
rdfs:comment "Any suture between cranial and/or facial bones." ;
rdfs:subClassOf obo:UBERON_0002209 .
obo:GO_0097152 a rdfs:Class ;
rdfs:label "mesenchymal cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." ;
rdfs:subClassOf obo:GO_0006915 .
obo:CL_0000723 a rdfs:Class ;
rdfs:label "somatic stem cell" ;
rdfs:comment "A stem cell that can give rise to cell types of the body other than those of the germ-line." ;
rdfs:subClassOf obo:CL_0000034 .
obo:CL_0002600 a rdfs:Class ;
rdfs:label "smooth muscle cell of trachea" ;
rdfs:comment "A smooth muscle cell of the trachea." ;
rdfs:subClassOf obo:CL_0000192 , obo:CL_0019019 .
obo:CHEBI_24712 a rdfs:Class ;
rdfs:label "hydroxymethyl group" ;
rdfs:subClassOf obo:CHEBI_50325 .
obo:UBERON_0006914 a rdfs:Class ;
rdfs:label "squamous epithelium" ;
rdfs:comment "An epithelium characterised by its most superficial layer consisting of squamous epithelial cells." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0051892 a rdfs:Class ;
rdfs:label "negative regulation of cardioblast differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ;
rdfs:subClassOf obo:GO_0051890 , obo:GO_0065007 , obo:GO_1905208 , obo:GO_2000737 .
obo:GO_1902510 a rdfs:Class ;
rdfs:label "regulation of apoptotic DNA fragmentation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903624 .
obo:PHIPO_0000033 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen growth on host surface" ;
rdfs:comment "A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is abnormal." .
obo:GO_0009792 a rdfs:Class ;
rdfs:label "embryo development ending in birth or egg hatching" ;
rdfs:comment "The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell." ;
rdfs:subClassOf obo:GO_0009790 .
obo:CL_0002321 a rdfs:Class ;
rdfs:label "embryonic cell (metazoa)" ;
rdfs:comment "A cell of the embryo." ;
rdfs:subClassOf obo:CL_0000000 .
obo:CL_0002368 a rdfs:Class ;
rdfs:label "respiratory tract epithelial cell" ;
rdfs:comment "An epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002076 .
obo:PHIPO_0001363 a rdfs:Class ;
rdfs:label "sensitive to isopyrazam" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to isopyrazam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1905082 a rdfs:Class ;
rdfs:label "regulation of mitochondrial translational elongation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mitochondrial translational elongation." ;
rdfs:subClassOf obo:GO_0006448 , obo:GO_0065007 .
obo:PR_000001889 a rdfs:Class ;
rdfs:label "CD14 molecule" ;
rdfs:comment "A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CL_2000093 a rdfs:Class ;
rdfs:label "bronchus fibroblast of lung" ;
rdfs:comment "Any fibroblast of lung that is part of a bronchus." ;
rdfs:subClassOf obo:CL_0002553 .
obo:CHEBI_24431 a rdfs:Class ;
rdfs:label "chemical entity" ;
rdfs:comment "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." ;
rdfs:subClassOf obo:BFO_0000040 .
obo:UBERON_0004291 a rdfs:Class ;
rdfs:label "heart rudiment" ;
rdfs:comment "A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." ;
rdfs:subClassOf obo:UBERON_0012275 .
obo:PHIPO_0001006 a rdfs:Class ;
rdfs:label "abnormal host morphology during pathogen invasion"@en ;
rdfs:comment "A pathogen host interaction phenotype where the morphology of the host during pathogen invasion is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0001002 .
obo:GO_1904092 a rdfs:Class ;
rdfs:label "regulation of autophagic cell death" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of autophagic cell death." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0065007 .
obo:GO_1903553 a rdfs:Class ;
rdfs:label "positive regulation of extracellular exosome assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902117 , obo:GO_1903551 .
obo:CHEBI_39141 a rdfs:Class ;
rdfs:label "Bronsted acid" ;
rdfs:comment "A molecular entity capable of donating a hydron to an acceptor (Brønsted base)." ;
rdfs:subClassOf obo:CHEBI_17891 , obo:CHEBI_37527 .
obo:GO_0050954 a rdfs:Class ;
rdfs:label "sensory perception of mechanical stimulus" ;
rdfs:comment "The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." ;
rdfs:subClassOf obo:GO_0007600 .
obo:CHEBI_79387 a rdfs:Class ;
rdfs:label "trivalent inorganic anion" ;
rdfs:comment "Any inorganic anion with a valency of three." ;
rdfs:subClassOf obo:CHEBI_24834 .
obo:GO_1904651 a rdfs:Class ;
rdfs:label "positive regulation of fat cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0065007 , obo:GO_1904649 .
obo:GO_0048599 a rdfs:Class ;
rdfs:label "oocyte development" ;
rdfs:comment "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0007281 , obo:GO_0032502 .
obo:GO_0002707 a rdfs:Class ;
rdfs:label "negative regulation of lymphocyte mediated immunity" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity." ;
rdfs:subClassOf obo:GO_0002704 , obo:GO_0002706 , obo:GO_0065007 .
obo:UBERON_0013755 a rdfs:Class ;
rdfs:label "arterial blood" ;
rdfs:comment "A blood that is part of a artery." ;
rdfs:subClassOf obo:UBERON_0000178 .
obo:GO_0060577 a rdfs:Class ;
rdfs:label "pulmonary vein morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048845 .
obo:GO_0014000 a rdfs:Class ;
rdfs:label "morula development" ;
rdfs:comment "The process whose specific outcome is the progression of the morula over time. The morula is a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum." ;
rdfs:subClassOf obo:GO_0009790 , obo:GO_0048856 .
obo:PHIPO_0001388 a rdfs:Class ;
rdfs:label "resistance to pyrisoxazole" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to pyrisoxazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0021644 a rdfs:Class ;
rdfs:label "vagus nerve morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0021602 .
obo:GO_0003277 a rdfs:Class ;
rdfs:label "apoptotic process involved in endocardial cushion morphogenesis" ;
rdfs:comment "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ;
rdfs:subClassOf obo:GO_0003278 , obo:GO_0006915 .
obo:CHEBI_23503 a rdfs:Class ;
rdfs:label "4-amino-1,2-oxazolidin-3-one" ;
rdfs:comment "A member of the class of oxazolidines that is isoxazoldin-3-one which is substituted at position 4 by an amino group." ;
rdfs:subClassOf obo:CHEBI_26649 , obo:CHEBI_38329 , obo:CHEBI_50994 , obo:CHEBI_75606 .
obo:CHEBI_10545 a rdfs:Class ;
rdfs:label "electron" ;
rdfs:comment "Elementary particle not affected by the strong force having a spin ½, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." ;
rdfs:subClassOf obo:CHEBI_36338 .
obo:GO_0008066 a rdfs:Class ;
rdfs:label "glutamate receptor activity" ;
rdfs:comment "Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0004888 , obo:GO_0038023 .
obo:CHEBI_83821 a rdfs:Class ;
rdfs:label "amino-acid derivative" ;
rdfs:comment "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:UBERON_0007651 a rdfs:Class ;
rdfs:label "anatomical junction" ;
rdfs:comment "An anatomical structure that connects two structures." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_1905559 a rdfs:Class ;
rdfs:label "positive regulation of mitotic nuclear envelope disassembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_0090068 , obo:GO_1905557 .
obo:GO_0060485 a rdfs:Class ;
rdfs:label "mesenchyme development" ;
rdfs:comment "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells." ;
rdfs:subClassOf obo:GO_0009888 , obo:GO_0048856 .
obo:GO_0002579 a rdfs:Class ;
rdfs:label "positive regulation of antigen processing and presentation" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002577 , obo:GO_0002684 , obo:GO_0065007 .
obo:GO_0045603 a rdfs:Class ;
rdfs:label "positive regulation of endothelial cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation." ;
rdfs:subClassOf obo:GO_0030858 , obo:GO_0045601 , obo:GO_0065007 .
obo:CHEBI_76661 a rdfs:Class ;
rdfs:label "EC 2.3.* (acyltransferase) inhibitor" ;
rdfs:comment "A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*)." ;
rdfs:subClassOf obo:CHEBI_71300 .
obo:GO_2001224 a rdfs:Class ;
rdfs:label "positive regulation of neuron migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuron migration." ;
rdfs:subClassOf obo:GO_0030335 , obo:GO_0065007 , obo:GO_2001222 .
obo:UBERON_0002072 a rdfs:Class ;
rdfs:label "hypodermis" ;
rdfs:comment "Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0013754 .
obo:UBERON_0014950 a rdfs:Class ;
rdfs:label "layer of developing cerebral cortex" ;
rdfs:subClassOf obo:UBERON_0005423 .
obo:CHEBI_142708 a rdfs:Class ;
rdfs:label "tigecycline(1+)" ;
rdfs:comment "An ammonium ion that is the conjugate acid of tigecycline; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35274 .
obo:CHEBI_36093 a rdfs:Class ;
rdfs:label "inorganic chloride" ;
rdfs:subClassOf obo:CHEBI_23114 , obo:CHEBI_24839 .
obo:CHEBI_25022 a rdfs:Class ;
rdfs:label "leucomycin" ;
rdfs:subClassOf obo:CHEBI_25106 .
obo:GO_0140387 a rdfs:Class ;
rdfs:label "negative regulation of L-glutamate biosynthetic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of L-glutamate biosynthetic process." ;
rdfs:subClassOf obo:GO_0062014 , obo:GO_0065007 , obo:GO_2000283 .
obo:GO_2000378 a rdfs:Class ;
rdfs:label "negative regulation of reactive oxygen species metabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0065007 , obo:GO_2000377 .
obo:GO_0042102 a rdfs:Class ;
rdfs:label "positive regulation of T cell proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of T cell proliferation." ;
rdfs:subClassOf obo:GO_0042129 , obo:GO_0050671 , obo:GO_0050870 , obo:GO_0065007 .
obo:PHIPO_0000114 a rdfs:Class ;
rdfs:label "increased pathogen penetration across the barrier"@en ;
rdfs:comment "A single species pathogen penetration phenotype in which the frequency of occurrence of pathogen penetration of a given experimental substance/membrane is increased." ;
rdfs:subClassOf obo:PHIPO_0000024 .
obo:PR_000044633 a rdfs:Class ;
rdfs:label "dopamine receptor" ;
rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human DRD1 to DRD5 genes, 1:1 orthologs thereof, or pro-orthologs thereof." ;
rdfs:subClassOf obo:PR_000001094 .
obo:GO_0035886 a rdfs:Class ;
rdfs:label "vascular associated smooth muscle cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0051145 .
obo:UBERON_0009758 a rdfs:Class ;
rdfs:label "abdominal ganglion" ;
rdfs:comment "A ganglion that is part of a abdominal segment of trunk." ;
rdfs:subClassOf obo:UBERON_0000045 , obo:UBERON_0007134 .
obo:GO_1901626 a rdfs:Class ;
rdfs:label "regulation of postsynaptic membrane organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of postsynaptic membrane organization." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0060537 a rdfs:Class ;
rdfs:label "muscle tissue development" ;
rdfs:comment "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers." ;
rdfs:subClassOf obo:GO_0009888 , obo:GO_0048856 .
obo:GO_0051380 a rdfs:Class ;
rdfs:label "norepinephrine binding" ;
rdfs:comment "Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0043169 , obo:GO_1901338 .
obo:UBERON_0001982 a rdfs:Class ;
rdfs:label "capillary" ;
rdfs:comment "Any of the smallest blood vessels connecting arterioles with venules." ;
rdfs:subClassOf obo:UBERON_8410081 .
obo:GO_0000313 a rdfs:Class ;
rdfs:label "organellar ribosome" ;
rdfs:comment "A ribosome contained within a subcellular membrane-bounded organelle." ;
rdfs:subClassOf obo:GO_0005840 .
obo:GO_2000172 a rdfs:Class ;
rdfs:label "regulation of branching morphogenesis of a nerve" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve." ;
rdfs:subClassOf obo:GO_0060688 , obo:GO_0065007 .
obo:PHIPO_0001370 a rdfs:Class ;
rdfs:label "resistance to pyrimorph" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to pyrimorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_48705 a rdfs:Class ;
rdfs:label "agonist" ;
rdfs:comment "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:CL_0002676 a rdfs:Class ;
rdfs:label "neural crest derived neuroblast" ;
rdfs:comment "A neuroblast derived from a neural crest cell." ;
rdfs:subClassOf obo:CL_0000031 .
obo:GO_0061550 a rdfs:Class ;
rdfs:label "cranial ganglion development" ;
rdfs:comment "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0061548 .
obo:GO_0046823 a rdfs:Class ;
rdfs:label "negative regulation of nucleocytoplasmic transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0046822 , obo:GO_0065007 .
obo:GO_0050962 a rdfs:Class ;
rdfs:label "detection of light stimulus involved in sensory perception" ;
rdfs:comment "The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light." ;
rdfs:subClassOf obo:GO_0009583 , obo:GO_0050906 .
obo:CHEBI_26440 a rdfs:Class ;
rdfs:label "pyrimidine nucleoside" ;
rdfs:subClassOf obo:CHEBI_33838 , obo:CHEBI_39447 .
obo:UBERON_0001901 a rdfs:Class ;
rdfs:label "epithelium of trachea" ;
rdfs:comment "The epithelial lining of the trachea which contains numerous ciliated cells." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0005911 , obo:UBERON_0008397 .
obo:CHEBI_131871 a rdfs:Class ;
rdfs:label "hydroxy polyunsaturated fatty acid anion" ;
rdfs:comment "Any polyunsaturated fatty acid anion carrying one or more hydroxy substituents." ;
rdfs:subClassOf obo:CHEBI_59835 , obo:CHEBI_76567 .
obo:GO_0048860 a rdfs:Class ;
rdfs:label "glioblast division" ;
rdfs:comment "The process resulting in the physical partitioning and separation of a glioblast into daughter cells." ;
rdfs:subClassOf obo:GO_0051301 .
obo:PHIPO_0000878 a rdfs:Class ;
rdfs:label "sensitive to fenpropidin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenpropidin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0037144 a rdfs:Class ;
rdfs:label "wall of heart" ;
rdfs:comment "Wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees." ;
rdfs:subClassOf obo:UBERON_0000060 .
obo:CHEBI_76946 a rdfs:Class ;
rdfs:label "fungal metabolite" ;
rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." ;
rdfs:subClassOf obo:CHEBI_75763 .
obo:GO_0035779 a rdfs:Class ;
rdfs:label "angioblast cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0048863 .
obo:GO_0034393 a rdfs:Class ;
rdfs:label "positive regulation of smooth muscle cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process." ;
rdfs:subClassOf obo:GO_0010661 , obo:GO_0034391 , obo:GO_0065007 .
obo:CHEBI_138103 a rdfs:Class ;
rdfs:label "inorganic acid" ;
rdfs:comment "A Brønsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." ;
rdfs:subClassOf obo:CHEBI_39141 .
obo:GO_0030308 a rdfs:Class ;
rdfs:label "negative regulation of cell growth" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." ;
rdfs:subClassOf obo:GO_0001558 , obo:GO_0045926 , obo:GO_0048523 , obo:GO_0065007 .
obo:PHIPO_0000691 a rdfs:Class ;
rdfs:label "resistance to emamectin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to emamectin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_36700 a rdfs:Class ;
rdfs:label "phosphocholines" ;
rdfs:comment "Any compound having phosphocholine as part of its structure." ;
rdfs:subClassOf obo:CHEBI_23213 , obo:CHEBI_23217 , obo:CHEBI_25703 , obo:CHEBI_37734 .
obo:UBERON_0000956 a rdfs:Class ;
rdfs:label "cerebral cortex" ;
rdfs:comment "The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex." ;
rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0016548 .
obo:PHIPO_0000743 a rdfs:Class ;
rdfs:label "sensitive to tridemorph"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tridemorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0002064 a rdfs:Class ;
rdfs:label "epithelial cell development" ;
rdfs:comment "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:GO_0019538 a rdfs:Class ;
rdfs:label "protein metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a protein. Includes protein modification." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0043170 , obo:GO_0044238 .
obo:UBERON_0003898 a rdfs:Class ;
rdfs:label "skeletal muscle tissue of trunk" ;
rdfs:comment "A portion of skeletal muscle tissue in the trunk." ;
rdfs:subClassOf obo:UBERON_0001134 .
obo:UBERON_0013127 a rdfs:Class ;
rdfs:label "pulmonary venous system" ;
rdfs:comment "The part of the venous system that drains the lungs[Kardong]." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:GO_0016917 a rdfs:Class ;
rdfs:label "GABA receptor activity" ;
rdfs:comment "Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms." ;
rdfs:subClassOf obo:GO_0004888 , obo:GO_0038023 .
obo:PHIPO_0000286 a rdfs:Class ;
rdfs:label "normal cellular pigment accumulation"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of coloring matter in a cell is normal." ;
rdfs:subClassOf obo:PHIPO_0000284 .
obo:GO_0021719 a rdfs:Class ;
rdfs:label "superior olivary nucleus morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." ;
rdfs:subClassOf obo:GO_0009653 .
obo:UBERON_0009618 a rdfs:Class ;
rdfs:label "trunk paraxial mesoderm" ;
rdfs:subClassOf obo:UBERON_0005256 .
obo:PHIPO_0001094 a rdfs:Class ;
rdfs:label "abnormal localization"@en ;
rdfs:comment "A single species phenotype where the localization of a structure or substance in a cell is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000235 .
obo:GO_0005929 a rdfs:Class ;
rdfs:label "cilium" ;
rdfs:comment "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." ;
rdfs:subClassOf obo:GO_0043227 , obo:GO_0120025 .
obo:GO_0051301 a rdfs:Class ;
rdfs:label "cell division" ;
rdfs:comment "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0043500 a rdfs:Class ;
rdfs:label "muscle adaptation" ;
rdfs:comment "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." ;
rdfs:subClassOf obo:GO_0003012 , obo:GO_0050896 .
obo:GO_0060324 a rdfs:Class ;
rdfs:label "face development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0012416 a rdfs:Class ;
rdfs:label "respiratory system arterial smooth muscle" ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004297 , obo:UBERON_0004695 .
obo:GO_0055001 a rdfs:Class ;
rdfs:label "muscle cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:UBERON_0006339 a rdfs:Class ;
rdfs:label "third ventricle choroid plexus stroma" ;
rdfs:comment "A choroid plexus stroma that is part of a third ventricle." ;
rdfs:subClassOf obo:UBERON_0005206 .
obo:UBERON_0016405 a rdfs:Class ;
rdfs:label "pulmonary capillary" ;
rdfs:comment "A capillary that is part of a lung." ;
rdfs:subClassOf obo:UBERON_0001982 , obo:UBERON_0003512 , obo:UBERON_0003526 .
obo:CHEBI_35516 a rdfs:Class ;
rdfs:label "cholestane" ;
rdfs:subClassOf obo:CHEBI_35508 .
obo:UBERON_0001007 a rdfs:Class ;
rdfs:label "digestive system" ;
rdfs:comment "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:GO_1903867 a rdfs:Class ;
rdfs:label "extraembryonic membrane development" ;
rdfs:comment "The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0048633 a rdfs:Class ;
rdfs:label "positive regulation of skeletal muscle tissue growth" ;
rdfs:comment "Any process that activates, maintains or increases the rate of skeletal muscle growth." ;
rdfs:subClassOf obo:GO_0048631 , obo:GO_0048639 , obo:GO_0048643 , obo:GO_0065007 .
obo:GO_0071345 a rdfs:Class ;
rdfs:label "cellular response to cytokine stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus." ;
rdfs:subClassOf obo:GO_0034097 .
obo:GO_0070228 a rdfs:Class ;
rdfs:label "regulation of lymphocyte apoptotic process" ;
rdfs:comment "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000106 .
obo:PHIPO_0001345 a rdfs:Class ;
rdfs:label "resistance to bitertanol" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to bitertanol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0002761 a rdfs:Class ;
rdfs:label "regulation of myeloid leukocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation." ;
rdfs:subClassOf obo:GO_0045637 , obo:GO_0065007 , obo:GO_1902105 .
obo:CL_0000058 a rdfs:Class ;
rdfs:label "chondroblast" ;
rdfs:comment "Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell." ;
rdfs:subClassOf obo:CL_0002320 , obo:CL_0011026 .
obo:UBERON_0004696 a rdfs:Class ;
rdfs:label "venous system smooth muscle" ;
rdfs:comment "A portion of smooth muscle tissue that is part of a venous system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004237 .
obo:UBERON_0006960 a rdfs:Class ;
rdfs:label "ovary stroma" ;
rdfs:comment "The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis." ;
rdfs:subClassOf obo:UBERON_0003891 , obo:UBERON_0005156 .
obo:UBERON_0002377 a rdfs:Class ;
rdfs:label "muscle of neck" ;
rdfs:comment "Any muscle that is part of the cervical (neck) region." ;
rdfs:subClassOf obo:UBERON_0010959 , obo:UBERON_0014892 .
obo:CL_0010021 a rdfs:Class ;
rdfs:label "cardiac myoblast" ;
rdfs:comment "Any myoblast that develops into some cardiac muscle cell." ;
rdfs:subClassOf obo:CL_0000056 .
obo:GO_0098883 a rdfs:Class ;
rdfs:label "synapse pruning" ;
rdfs:comment "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0050808 , obo:GO_0150146 .
obo:UBERON_0019291 a rdfs:Class ;
rdfs:label "white matter of metencephalon" ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0019258 .
obo:PHIPO_0000555 a rdfs:Class ;
rdfs:label "resistance to tetracycline"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tetracycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0002061 a rdfs:Class ;
rdfs:label "truncus arteriosus" ;
rdfs:comment "The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0002050 , obo:UBERON_0003498 .
obo:GO_0060976 a rdfs:Class ;
rdfs:label "coronary vasculature development" ;
rdfs:comment "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0001568 , obo:GO_0048856 .
obo:PHIPO_0001089 a rdfs:Class ;
rdfs:label "decreased rate of germination tube formation"@en ;
rdfs:comment "An individual organism growth phenotype in which the rate, or speed, of germ tube formation is decreased resulting in decreased hyphal growth." ;
rdfs:subClassOf obo:PHIPO_0001212 .
obo:GO_0035282 a rdfs:Class ;
rdfs:label "segmentation" ;
rdfs:comment "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis." ;
rdfs:subClassOf obo:GO_0003002 .
obo:CHEBI_62031 a rdfs:Class ;
rdfs:label "polar amino acid zwitterion" ;
rdfs:comment "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:GO_0048812 a rdfs:Class ;
rdfs:label "neuron projection morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0120039 .
obo:GO_0048592 a rdfs:Class ;
rdfs:label "eye morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the eye are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0090596 .
obo:UBERON_0002080 a rdfs:Class ;
rdfs:label "heart right ventricle" ;
rdfs:comment "A cardiac ventricle that is in the right side of the heart." ;
rdfs:subClassOf obo:UBERON_0002082 , obo:UBERON_0035554 .
obo:CHEBI_76773 a rdfs:Class ;
rdfs:label "EC 3.1.1.* (carboxylic ester hydrolase) inhibitor" ;
rdfs:comment "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*)." ;
rdfs:subClassOf obo:CHEBI_76760 .
obo:PHIPO_0001135 a rdfs:Class ;
rdfs:label "sensitive to sorbitol"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to sorbitol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_3478 a rdfs:Class ;
rdfs:label "cefaclor" ;
rdfs:comment "A cephalosporin bearing chloro and (R)-2-amino-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton." ;
rdfs:subClassOf obo:CHEBI_23066 .
a rdfs:Class ;
rdfs:label "Pons, motor related" ;
rdfs:subClassOf obo:BFO_0000004 .
obo:CHEBI_623918 a rdfs:Class ;
rdfs:label "nikkomycin Z" ;
rdfs:comment "A uridine-based nucleoside-peptide antibiotic which inhibits fungal chitin biosynthesis by inhibiting chitin synthase." ;
rdfs:subClassOf obo:CHEBI_59668 .
obo:GO_0021555 a rdfs:Class ;
rdfs:label "midbrain-hindbrain boundary morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048598 .
obo:GO_0001501 a rdfs:Class ;
rdfs:label "skeletal system development" ;
rdfs:comment "The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:GO_2001205 a rdfs:Class ;
rdfs:label "negative regulation of osteoclast development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development." ;
rdfs:subClassOf obo:GO_0045671 , obo:GO_0065007 , obo:GO_2001204 .
obo:CHEBI_26199 a rdfs:Class ;
rdfs:label "polyprenol" ;
rdfs:comment "Any member of the class of prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units." ;
rdfs:subClassOf obo:CHEBI_26244 .
obo:UBERON_0011222 a rdfs:Class ;
rdfs:label "intra-ocular muscle" ;
rdfs:subClassOf obo:UBERON_0004277 .
obo:GO_1904810 a rdfs:Class ;
rdfs:label "negative regulation of dense core granule transport" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0065007 , obo:GO_1904809 .
obo:GO_1901951 a rdfs:Class ;
rdfs:label "regulation of anterograde dense core granule transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of anterograde dense core granule transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901608 , obo:GO_1904809 .
obo:GO_0043936 a rdfs:Class ;
rdfs:label "asexual sporulation resulting in formation of a cellular spore" ;
rdfs:comment "The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction." ;
rdfs:subClassOf obo:GO_0030435 , obo:GO_0030436 .
obo:GO_0034050 a rdfs:Class ;
rdfs:label "symbiont-induced defense-related programmed cell death" ;
rdfs:comment "Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules." ;
rdfs:subClassOf obo:GO_0012501 , obo:GO_0140546 .
obo:GO_0051254 a rdfs:Class ;
rdfs:label "positive regulation of RNA metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." ;
rdfs:subClassOf obo:GO_0010604 , obo:GO_0051252 , obo:GO_0065007 .
obo:GO_0003204 a rdfs:Class ;
rdfs:label "cardiac skeleton development" ;
rdfs:comment "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0061448 .
obo:GO_1900150 a rdfs:Class ;
rdfs:label "regulation of defense response to fungus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of defense response to fungus." ;
rdfs:subClassOf obo:GO_0002831 , obo:GO_0031347 , obo:GO_0032101 , obo:GO_0065007 .
obo:GO_0002309 a rdfs:Class ;
rdfs:label "T cell proliferation involved in immune response" ;
rdfs:comment "The expansion of a T cell population by cell division as part of an immune response." ;
rdfs:subClassOf obo:GO_0002286 , obo:GO_0042098 .
obo:CL_0001029 a rdfs:Class ;
rdfs:label "common dendritic progenitor" ;
rdfs:comment "Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers." ;
rdfs:subClassOf obo:CL_0001019 , obo:CL_0002031 .
obo:GO_0021588 a rdfs:Class ;
rdfs:label "cerebellum formation" ;
rdfs:comment "The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CHEBI_63611 a rdfs:Class ;
rdfs:label "moxifloxacin" ;
rdfs:comment "A quinolone that consists of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid bearing a cyclopropyl substituent at position 1, a fluoro substitiuent at position 6, a (4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl group at position 7 and a methoxy substituent at position 8. A member of the fluoroquinolone class of antibacterial agents." ;
rdfs:subClassOf obo:CHEBI_23765 , obo:CHEBI_26512 , obo:CHEBI_35618 , obo:CHEBI_51454 , obo:CHEBI_63697 , obo:CHEBI_86324 , obo:CHEBI_87211 .
obo:GO_0051457 a rdfs:Class ;
rdfs:label "maintenance of protein location in nucleus" ;
rdfs:comment "Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0072595 .
obo:UBERON_0011862 a rdfs:Class ;
rdfs:label "pulmonary collagen fibril" ;
rdfs:comment "The connective tissue bundles in the extracellular matrix of pulmonary tissue that are composed of collagen, and play a role in tissue strength and elasticity." ;
rdfs:subClassOf obo:UBERON_0011860 .
obo:UBERON_0003496 a rdfs:Class ;
rdfs:label "head blood vessel" ;
rdfs:comment "A blood vessel that is part of a head [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:CHEBI_35267 a rdfs:Class ;
rdfs:label "quaternary ammonium ion" ;
rdfs:comment "A derivative of ammonium, NH4+, in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_1901342 a rdfs:Class ;
rdfs:label "regulation of vasculature development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vasculature development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000026 .
obo:UBERON_0036217 a rdfs:Class ;
rdfs:label "coelomic fluid" ;
rdfs:comment "A bodily fluid that is located in the coelom." ;
rdfs:subClassOf obo:UBERON_0006314 .
obo:GO_0014014 a rdfs:Class ;
rdfs:label "negative regulation of gliogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia." ;
rdfs:subClassOf obo:GO_0014013 , obo:GO_0050768 , obo:GO_0065007 .
obo:UBERON_0003386 a rdfs:Class ;
rdfs:label "smooth muscle of eye" ;
rdfs:comment "Any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi." ;
rdfs:subClassOf obo:UBERON_0001135 .
obo:UBERON_0004471 a rdfs:Class ;
rdfs:label "musculature of pectoral girdle" ;
rdfs:comment "A subdivision of the musculature of the body in the pectoral girdle region. Includes pectoral and shoulder muscles." ;
rdfs:subClassOf obo:UBERON_0001015 , obo:UBERON_0014793 .
obo:CHEBI_25806 a rdfs:Class ;
rdfs:label "oxygen molecular entity" ;
rdfs:subClassOf obo:CHEBI_33304 .
obo:UBERON_0005204 a rdfs:Class ;
rdfs:label "larynx submucosa gland" ;
rdfs:comment "A gland that is part of a larynx submucosa [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002530 , obo:UBERON_0036225 .
obo:CHEBI_83780 a rdfs:Class ;
rdfs:label "(S)-tebuconazole" ;
rdfs:comment "The (S)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol." ;
rdfs:subClassOf obo:CHEBI_83779 .
obo:GO_0042307 a rdfs:Class ;
rdfs:label "positive regulation of protein import into nucleus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus." ;
rdfs:subClassOf obo:GO_0042306 , obo:GO_0046824 , obo:GO_0065007 , obo:GO_0090316 , obo:GO_1900182 .
obo:GO_0030016 a rdfs:Class ;
rdfs:label "myofibril" ;
rdfs:comment "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." ;
rdfs:subClassOf obo:GO_0043292 .
obo:GO_0099124 a rdfs:Class ;
rdfs:label "axonal dopamine secretion" ;
rdfs:comment "The regulated release of dopamine from an axon." ;
rdfs:subClassOf obo:GO_0014046 , obo:GO_0051649 .
obo:GO_1903337 a rdfs:Class ;
rdfs:label "positive regulation of vacuolar transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vacuolar transport." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0065007 , obo:GO_1903335 .
obo:CL_0005024 a rdfs:Class ;
rdfs:label "somatomotor neuron"@en ;
rdfs:comment "A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic." ;
rdfs:subClassOf obo:CL_0000100 , obo:CL_0000108 .
obo:RO_0002120 a rdf:Property ;
rdfs:label "synapsed to"@en ;
rdfs:comment """ Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.
"""@en ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002486 .
obo:CL_0000766 a rdfs:Class ;
rdfs:label "myeloid leukocyte" ;
rdfs:comment "A cell of the monocyte, granulocyte, or mast cell lineage." ;
rdfs:subClassOf obo:CL_0000738 , obo:CL_0000763 .
obo:CHEBI_27136 a rdfs:Class ;
rdfs:label "triol" ;
rdfs:comment "A chemical compound containing three hydroxy groups." ;
rdfs:subClassOf obo:CHEBI_26191 .
obo:GO_0046887 a rdfs:Class ;
rdfs:label "positive regulation of hormone secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell." ;
rdfs:subClassOf obo:GO_0010647 , obo:GO_0023056 , obo:GO_0046883 , obo:GO_0065007 , obo:GO_1903532 .
obo:UBERON_0005906 a rdfs:Class ;
rdfs:label "serous sac" ;
rdfs:comment "Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:CHEBI_78379 a rdfs:Class ;
rdfs:label "EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor" ;
rdfs:comment "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7)." ;
rdfs:subClassOf obo:CHEBI_76663 .
obo:GO_0007154 a rdfs:Class ;
rdfs:label "cell communication" ;
rdfs:comment "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0009987 .
obo:CHEBI_35526 a rdfs:Class ;
rdfs:label "hypoglycemic agent" ;
rdfs:comment "A drug which lowers the blood glucose level." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0110123 a rdfs:Class ;
rdfs:label "regulation of myotube cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of myotube cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:GO_0006896 a rdfs:Class ;
rdfs:label "Golgi to vacuole transport" ;
rdfs:comment "The directed movement of substances from the Golgi to the vacuole." ;
rdfs:subClassOf obo:GO_0006892 , obo:GO_0007034 , obo:GO_0010496 , obo:GO_0016192 .
obo:GO_1905923 a rdfs:Class ;
rdfs:label "positive regulation of acetylcholine biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0060409 , obo:GO_0065007 , obo:GO_1905921 .
obo:GO_0035906 a rdfs:Class ;
rdfs:label "descending aorta development" ;
rdfs:comment "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0021684 a rdfs:Class ;
rdfs:label "cerebellar granular layer formation" ;
rdfs:comment "The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CHEBI_36344 a rdfs:Class ;
rdfs:label "hadron" ;
rdfs:comment "Hadron is a subatomic particle which experiences the strong force." ;
rdfs:subClassOf obo:CHEBI_36343 .
obo:NCBITaxon_1963758 a rdfs:Class ;
rdfs:label "Myomorpha" ;
rdfs:subClassOf obo:NCBITaxon_9989 .
obo:PHIPO_0000532 a rdfs:Class ;
rdfs:label "resistance to oxytetracycline"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to oxytetracycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000297 a rdfs:Class ;
rdfs:label "obsolete normal dissemination of pathogen sexual product" .
obo:PHIPO_0000464 a rdfs:Class ;
rdfs:label "obsolete host necrotic cell death phenotype in response to pathogen" ;
rdfs:comment "A phenotype affecting the process of host tissue cell death caused by the pathogen (GO:0097300 part of GO:0009608 )." .
obo:CHEBI_33791 a rdfs:Class ;
rdfs:label "canonical nucleoside residue" ;
rdfs:subClassOf obo:CHEBI_50320 .
obo:CL_0008002 a rdfs:Class ;
rdfs:label "skeletal muscle fiber"@en ;
rdfs:comment "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ;
rdfs:subClassOf obo:CL_0000187 , obo:CL_0000188 , obo:CL_0002372 .
obo:GO_0042582 a rdfs:Class ;
rdfs:label "azurophil granule" ;
rdfs:comment "Primary lysosomal granule readily stainable with a Romanowsky stain." ;
rdfs:subClassOf obo:GO_0005766 , obo:GO_0030141 .
obo:GO_1904933 a rdfs:Class ;
rdfs:label "regulation of cell proliferation in midbrain" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell proliferation in midbrain." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000177 .
obo:CHEBI_37852 a rdfs:Class ;
rdfs:label "organoammonium sulfate salt" ;
rdfs:subClassOf obo:CHEBI_46850 , obo:CHEBI_51337 .
obo:CHEBI_38166 a rdfs:Class ;
rdfs:label "organic heteropolycyclic compound" ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33671 .
obo:GO_0021535 a rdfs:Class ;
rdfs:label "cell migration in hindbrain" ;
rdfs:comment "The orderly movement of a cell that will reside in the hindbrain." ;
rdfs:subClassOf obo:GO_0016477 .
obo:CHEBI_33655 a rdfs:Class ;
rdfs:label "aromatic compound" ;
rdfs:comment "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:GO_0001959 a rdfs:Class ;
rdfs:label "regulation of cytokine-mediated signaling pathway" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0060759 , obo:GO_0065007 .
obo:CHEBI_3749 a rdfs:Class ;
rdfs:label "clofazimine" ;
rdfs:comment "3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients." ;
rdfs:subClassOf obo:CHEBI_39201 , obo:CHEBI_83403 .
obo:GO_0032967 a rdfs:Class ;
rdfs:label "positive regulation of collagen biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0010714 , obo:GO_0032965 , obo:GO_0065007 .
obo:GO_0005518 a rdfs:Class ;
rdfs:label "collagen binding" ;
rdfs:comment "Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0044877 .
obo:GO_0045664 a rdfs:Class ;
rdfs:label "regulation of neuron differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuron differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:PHIPO_0000647 a rdfs:Class ;
rdfs:label "resistance to abamectin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to abamectin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_0000764 a rdfs:Class ;
rdfs:label "erythroid lineage cell" ;
rdfs:comment "A immature or mature cell in the lineage leading to and including erythrocytes." ;
rdfs:subClassOf obo:CL_0000763 .
obo:PHIPO_0000001 a rdfs:Class ;
rdfs:label "pathogen host interaction phenotype" ;
rdfs:comment "Any of the set of observable characteristics arising from the interaction of a potentially pathogenic organism with a host organism." ;
rdfs:subClassOf obo:PHIPO_0000505 .
obo:GO_1905939 a rdfs:Class ;
rdfs:label "regulation of gonad development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gonad development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 , obo:GO_2000241 .
obo:PHIPO_0000562 a rdfs:Class ;
rdfs:label "resistance to trovafloxacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to trovafloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0007503 a rdfs:Class ;
rdfs:label "epithelial vesicle" ;
rdfs:comment "A closed epithelium with a lumen." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0098542 a rdfs:Class ;
rdfs:label "defense response to other organism" ;
rdfs:comment "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." ;
rdfs:subClassOf obo:GO_0006952 , obo:GO_0051707 .
obo:CLM_1000056 a rdfs:Class ;
rdfs:label "NS forest marker set of tracheobronchial smooth muscle cell (Human lung)." ;
rdfs:subClassOf obo:SO_0001260 .
obo:GO_1905276 a rdfs:Class ;
rdfs:label "regulation of epithelial tube formation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of epithelial tube formation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905330 , obo:GO_2000026 .
obo:GO_0060092 a rdfs:Class ;
rdfs:label "regulation of synaptic transmission, glycinergic" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 .
obo:UBERON_0009881 a rdfs:Class ;
rdfs:label "anterior lateral plate mesoderm" ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:GO_1905555 a rdfs:Class ;
rdfs:label "positive regulation of blood vessel branching" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of blood vessel branching." ;
rdfs:subClassOf obo:GO_0045766 , obo:GO_0065007 , obo:GO_1905332 , obo:GO_1905553 .
obo:GO_0051049 a rdfs:Class ;
rdfs:label "regulation of transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032879 , obo:GO_0065007 .
obo:CL_4306992 a rdfs:Class ;
rdfs:label "DCO Il22 Gly-Gaba_2 cerebellar neuron (Mmus)" ;
rdfs:comment "A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Il22 (Mmus), Edaradd (Mmus). It is distinguished from other DCO Il22 Gly-Gaba cells by expression of Ppp1r17. It is GABAergic and glycinergic (inferred from expression of Slc32a1, Hdc, Slc6a5, Gad2, Gad1). These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Paraflocculus, arbor vitae, Dorsal cochlear nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5172 DCO Il22 Gly-Gaba_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300348 .
obo:GO_1901551 a rdfs:Class ;
rdfs:label "negative regulation of endothelial cell development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0045602 , obo:GO_0065007 , obo:GO_1901550 .
obo:CHEBI_192979 a rdfs:Class ;
rdfs:label "nystatin A2" ;
rdfs:subClassOf obo:CHEBI_59676 .
obo:GO_0022010 a rdfs:Class ;
rdfs:label "central nervous system myelination" ;
rdfs:comment "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." ;
rdfs:subClassOf obo:GO_0032291 , obo:GO_0042552 .
obo:GO_0007565 a rdfs:Class ;
rdfs:label "female pregnancy" ;
rdfs:comment "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." ;
rdfs:subClassOf obo:GO_0044703 , obo:GO_0044706 .
obo:CL_0011005 a rdfs:Class ;
rdfs:label "GABAergic interneuron" ;
rdfs:comment "An interneuron that uses GABA as a vesicular neurotransmitter. These interneurons are inhibitory" ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_0000498 , obo:CL_0000617 .
obo:GO_1905902 a rdfs:Class ;
rdfs:label "regulation of mesoderm formation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mesoderm formation." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0009891 a rdfs:Class ;
rdfs:label "positive regulation of biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0009893 , obo:GO_0065007 .
obo:UBERON_0003711 a rdfs:Class ;
rdfs:label "brachiocephalic vein" ;
rdfs:comment "The left and right brachiocephalic veins in the upper chest are formed by the union of each corresponding internal jugular vein and subclavian vein. This is at the level of the sternoclavicular joint. These great vessels merge to form the superior vena cava. The brachiocephalic veins are the major veins returning blood to the superior vena cava." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:UBERON_0004449 a rdfs:Class ;
rdfs:label "cerebral artery" ;
rdfs:comment "One of three main pairs of arteries and their branches, which irrigate the cerebrum of the brain." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0004573 .
obo:GO_0098751 a rdfs:Class ;
rdfs:label "bone cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:CHEBI_63607 a rdfs:Class ;
rdfs:label "linezolid" ;
rdfs:comment "An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex." ;
rdfs:subClassOf obo:CHEBI_22160 , obo:CHEBI_37143 , obo:CHEBI_38785 , obo:CHEBI_55374 .
obo:GO_0048070 a rdfs:Class ;
rdfs:label "regulation of developmental pigmentation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120305 .
obo:GO_0007498 a rdfs:Class ;
rdfs:label "mesoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." ;
rdfs:subClassOf obo:GO_0009888 , obo:GO_0048856 .
obo:CHEBI_22562 a rdfs:Class ;
rdfs:label "anilines" ;
rdfs:comment "Any aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_33860 .
obo:PHIPO_0000380 a rdfs:Class ;
rdfs:label "normal transporter activity"@en ;
rdfs:comment "A molecular function phenotype in which the observed rate of a specified transporter activity is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000409 .
obo:GO_0010710 a rdfs:Class ;
rdfs:label "regulation of collagen catabolic process" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0010712 , obo:GO_0065007 .
obo:GO_0045087 a rdfs:Class ;
rdfs:label "innate immune response" ;
rdfs:comment "Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." ;
rdfs:subClassOf obo:GO_0006955 , obo:GO_0140546 .
obo:GO_1905651 a rdfs:Class ;
rdfs:label "regulation of artery morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of artery morphogenesis." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0065007 .
obo:UBERON_0010499 a rdfs:Class ;
rdfs:label "pseudostratified ciliated columnar epithelium" ;
rdfs:comment "Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile." ;
rdfs:subClassOf obo:UBERON_0007592 , obo:UBERON_0010498 .
obo:PHIPO_0000581 a rdfs:Class ;
rdfs:label "resistance to flucytosine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to flucytosine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0061325 a rdfs:Class ;
rdfs:label "cell proliferation involved in outflow tract morphogenesis" ;
rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0061323 .
obo:CHEBI_21731 a rdfs:Class ;
rdfs:label "N-glycosyl compound" ;
rdfs:comment "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond." ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_63161 .
obo:GO_0060928 a rdfs:Class ;
rdfs:label "atrioventricular node cell development" ;
rdfs:comment "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state." ;
rdfs:subClassOf obo:GO_0048468 , obo:GO_0060926 .
obo:GO_0072665 a rdfs:Class ;
rdfs:label "protein localization to vacuole" ;
rdfs:comment "A process in which a protein is transported to, or maintained at, a location in a vacuole." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033365 .
obo:GO_0021762 a rdfs:Class ;
rdfs:label "substantia nigra development" ;
rdfs:comment "The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis)." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048857 .
obo:UBERON_0019261 a rdfs:Class ;
rdfs:label "white matter of forebrain" ;
rdfs:comment "A white matter that is part of the forebrain." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0003544 .
obo:GO_0043501 a rdfs:Class ;
rdfs:label "skeletal muscle adaptation" ;
rdfs:comment "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals." ;
rdfs:subClassOf obo:GO_0014888 , obo:GO_0043500 .
obo:GO_0001831 a rdfs:Class ;
rdfs:label "trophectodermal cellular morphogenesis" ;
rdfs:comment "The morphogenesis of trophectoderm cells." ;
rdfs:subClassOf obo:GO_0000902 , obo:GO_0009653 , obo:GO_0048598 .
obo:UBERON_0001179 a rdfs:Class ;
rdfs:label "peritoneal cavity" ;
rdfs:comment "Anatomical cavity bounded by visceral and parietal peritoneum." ;
rdfs:subClassOf obo:UBERON_0002553 , obo:UBERON_0035809 .
obo:GO_0061972 a rdfs:Class ;
rdfs:label "dermal bone morphogenesis" ;
rdfs:comment "The process in which bone which forms superficially in the organism are generated and organized." ;
rdfs:subClassOf obo:GO_0060349 , obo:GO_0061973 .
obo:GO_0042646 a rdfs:Class ;
rdfs:label "plastid nucleoid" ;
rdfs:comment "The region of a plastid to which the DNA is confined." ;
rdfs:subClassOf obo:GO_0009295 , obo:GO_0043232 .
obo:PR_000002978 a rdfs:Class ;
rdfs:label "lymphocyte antigen 6G" ;
rdfs:comment "An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000002976 .
obo:PHIPO_0000538 a rdfs:Class ;
rdfs:label "resistance to isoniazid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to isoniazid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0030199 a rdfs:Class ;
rdfs:label "collagen fibril organization" ;
rdfs:comment "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0030198 .
obo:GO_1901148 a rdfs:Class ;
rdfs:label "gene expression involved in extracellular matrix organization" ;
rdfs:comment "Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form." ;
rdfs:subClassOf obo:GO_0010467 .
obo:GO_0007039 a rdfs:Class ;
rdfs:label "protein catabolic process in the vacuole" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." ;
rdfs:subClassOf obo:GO_0030163 .
obo:GO_1905806 a rdfs:Class ;
rdfs:label "regulation of synapse pruning" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of synapse pruning." ;
rdfs:subClassOf obo:GO_0050807 , obo:GO_0065007 .
obo:CL_0010012 a rdfs:Class ;
rdfs:label "cerebral cortex neuron" ;
rdfs:comment "A CNS neuron of the cerebral cortex." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_0012001 .
obo:PHIPO_0000024 a rdfs:Class ;
rdfs:label "pathogen penetration across the barrier present" ;
rdfs:comment "A single species pathogen penetration phenotype in which pathogen penetration of a given experimental substance/membrane is present." ;
rdfs:subClassOf obo:PHIPO_0000160 .
obo:CL_4300367 a rdfs:Class ;
rdfs:label "oligodendrocyte (Mmus)" ;
rdfs:comment "A oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Gjc3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:327 Oligo NN." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000128 , obo:CL_4300031 .
obo:CL_0000174 a rdfs:Class ;
rdfs:label "steroid hormone secreting cell" ;
rdfs:comment "Any secretory cell that is capable of some steroid hormone secretion." ;
rdfs:subClassOf obo:CL_0000151 .
obo:GO_0032534 a rdfs:Class ;
rdfs:label "regulation of microvillus assembly" ;
rdfs:comment "A process that modulates the formation of a microvillus." ;
rdfs:subClassOf obo:GO_0032530 , obo:GO_0065007 , obo:GO_0120032 .
obo:GO_0034614 a rdfs:Class ;
rdfs:label "cellular response to reactive oxygen species" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." ;
rdfs:subClassOf obo:GO_0000302 , obo:GO_0034599 , obo:GO_0070887 , obo:GO_1901701 .
obo:GO_0060540 a rdfs:Class ;
rdfs:label "diaphragm morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the diaphragm are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048644 .
obo:CHEBI_63726 a rdfs:Class ;
rdfs:label "neuroprotective agent" ;
rdfs:comment "Any compound that can be used for the treatment of neurodegenerative disorders." ;
rdfs:subClassOf obo:CHEBI_50267 .
obo:CHEBI_23824 a rdfs:Class ;
rdfs:label "diol" ;
rdfs:comment "A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols." ;
rdfs:subClassOf obo:CHEBI_26191 .
obo:PHIPO_0000599 a rdfs:Class ;
rdfs:label "resistance to telithromycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to telithromycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0061855 a rdfs:Class ;
rdfs:label "negative regulation of neuroblast migration" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration." ;
rdfs:subClassOf obo:GO_0030336 , obo:GO_0061853 , obo:GO_0065007 .
obo:GO_2000727 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051155 , obo:GO_0065007 , obo:GO_1905209 , obo:GO_2000725 .
obo:GO_0035295 a rdfs:Class ;
rdfs:label "tube development" ;
rdfs:comment "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0005844 a rdfs:Class ;
rdfs:label "spinal cord segment" ;
rdfs:subClassOf obo:UBERON_0001948 .
obo:CL_4042035 a rdfs:Class ;
rdfs:label "molecular layer interneuron"@en ;
rdfs:comment "A type of cerebellar inhibitory GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell type inhibits Purkinje cells and other molecular layer interneurons. This interneuron plays a crucial role in regulating cerebellar output through feedforward inhibition and is characterized by its fast-spiking properties." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_4023057 .
obo:CHEBI_81822 a rdfs:Class ;
rdfs:label "boscalid" ;
rdfs:comment "A pyridinecarboxamide obtained by formal condensation of the carboxy group of 2-chloronicotinic acid with the amino group of 4'-chlorobiphenyl-2-amine. A fungicide active against a broad range of fungal pathogens including Botrytis spp., Alternaria spp. and Sclerotinia spp. for use on a wide range of crops including fruit, vegetables and ornamentals." ;
rdfs:subClassOf obo:CHEBI_22888 , obo:CHEBI_25529 , obo:CHEBI_62733 , obo:CHEBI_83403 , obo:CHEBI_87015 .
obo:GO_0086001 a rdfs:Class ;
rdfs:label "cardiac muscle cell action potential" ;
rdfs:comment "An action potential that occurs in a cardiac muscle cell." ;
rdfs:subClassOf obo:GO_0001508 .
obo:PHIPO_0000157 a rdfs:Class ;
rdfs:label "obsolete motility phenotype" ;
rdfs:comment "This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype." .
obo:CHEBI_27363 a rdfs:Class ;
rdfs:label "zinc atom" ;
rdfs:subClassOf obo:CHEBI_33340 .
obo:PHIPO_0000724 a rdfs:Class ;
rdfs:label "sensitive to alexidine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to alexidine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0011767 a rdfs:Class ;
rdfs:label "right recurrent laryngeal nerve" ;
rdfs:subClassOf obo:UBERON_0003716 , obo:UBERON_0015212 .
obo:GO_0007020 a rdfs:Class ;
rdfs:label "microtubule nucleation" ;
rdfs:comment "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." ;
rdfs:subClassOf obo:GO_0000226 .
obo:GO_0061185 a rdfs:Class ;
rdfs:label "negative regulation of dermatome development" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." ;
rdfs:subClassOf obo:GO_0045992 , obo:GO_0061183 , obo:GO_0065007 .
obo:GO_2001252 a rdfs:Class ;
rdfs:label "positive regulation of chromosome organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chromosome organization." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0033044 , obo:GO_0065007 .
obo:PHIPO_0000254 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host interaction RNA localization" ;
rdfs:comment "A pathogen host interaction phenotype in which the localization of an RNA in a cell is normal (i.e. indistinguishable from wild type)." .
obo:GO_1903430 a rdfs:Class ;
rdfs:label "negative regulation of cell maturation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0065007 , obo:GO_1903429 .
obo:GO_0030247 a rdfs:Class ;
rdfs:label "polysaccharide binding" ;
rdfs:comment "Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0030246 .
obo:GO_0097190 a rdfs:Class ;
rdfs:label "apoptotic signaling pathway" ;
rdfs:comment "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." ;
rdfs:subClassOf obo:GO_0007165 .
obo:PHIPO_0000994 a rdfs:Class ;
rdfs:label "obsolete decreased RNA level in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of RNA measured in a pathogen or host cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." .
obo:PHIPO_0000080 a rdfs:Class ;
rdfs:label "normal asexual sporulation"@en ;
rdfs:comment "A reproductive phenotype where the process of asexual sporulation, the formation of spores derived from the products of an asexual cell division, is normal (GO:0030436)." ;
rdfs:subClassOf obo:PHIPO_0000045 .
obo:CHEBI_51177 a rdfs:Class ;
rdfs:label "antitussive" ;
rdfs:comment "An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:CHEBI_76895 a rdfs:Class ;
rdfs:label "EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor" ;
rdfs:comment "An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*)." ;
rdfs:subClassOf obo:CHEBI_73216 .
obo:PHIPO_0000875 a rdfs:Class ;
rdfs:label "sensitive to verapamil"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to verapamil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_76815 a rdfs:Class ;
rdfs:label "EC 2.7.7.* (nucleotidyltransferase) inhibitor" ;
rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*)." ;
rdfs:subClassOf obo:CHEBI_76668 .
obo:CL_4307033 a rdfs:Class ;
rdfs:label "Astro-NT NN_1 Mecom astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dao (Mmus), Mecom (Mmus), Fbln5 (Mmus), Prelp (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Mecom, Prelp. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Ventral cochlear nucleus, Paraflocculus, Flocculus, Dorsal cochlear nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5213 Astro-NT NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301589 .
obo:GO_1904339 a rdfs:Class ;
rdfs:label "negative regulation of dopaminergic neuron differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation." ;
rdfs:subClassOf obo:GO_0045665 , obo:GO_0065007 , obo:GO_1904338 .
obo:GO_1902038 a rdfs:Class ;
rdfs:label "positive regulation of hematopoietic stem cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901534 , obo:GO_1902036 , obo:GO_2000738 .
obo:CHEBI_35476 a rdfs:Class ;
rdfs:label "antipsychotic agent" ;
rdfs:comment "Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect." ;
rdfs:subClassOf obo:CHEBI_35473 .
obo:PHIPO_0000551 a rdfs:Class ;
rdfs:label "resistance to brassinin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to brassinin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0045639 a rdfs:Class ;
rdfs:label "positive regulation of myeloid cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0045637 , obo:GO_0065007 .
obo:GO_0048799 a rdfs:Class ;
rdfs:label "animal organ maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
a rdfs:Class ;
rdfs:label "Thalamus" ;
rdfs:subClassOf , obo:UBERON_0001897 .
obo:CHEBI_35903 a rdfs:Class ;
rdfs:label "oxo carboxylic acid anion" ;
rdfs:comment "Any carboxylic acid anion containing at least one oxo group." ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:GO_0001944 a rdfs:Class ;
rdfs:label "vasculature development" ;
rdfs:comment "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:GO_1904625 a rdfs:Class ;
rdfs:label "negative regulation of glycine secretion, neurotransmission" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission." ;
rdfs:subClassOf obo:GO_0032891 , obo:GO_0046929 , obo:GO_0051956 , obo:GO_0060093 , obo:GO_0065007 , obo:GO_1904624 .
obo:GO_0101024 a rdfs:Class ;
rdfs:label "mitotic nuclear membrane organization" ;
rdfs:comment "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis." ;
rdfs:subClassOf obo:GO_0071763 , obo:GO_1903047 .
obo:PR_000015557 a rdfs:Class ;
rdfs:label "spondin-1" ;
rdfs:comment "A protein that is a translation product of the human SPON1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PHIPO_0000215 a rdfs:Class ;
rdfs:label "host chlorosis present in presence of pathogen"@en ;
rdfs:comment "A pathogen-host interaction phenotype in which host chlorosis is present." ;
rdfs:subClassOf obo:PHIPO_0000200 .
obo:GO_2000351 a rdfs:Class ;
rdfs:label "regulation of endothelial cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:GO_0048521 a rdfs:Class ;
rdfs:label "negative regulation of behavior" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ;
rdfs:subClassOf obo:GO_0050795 , obo:GO_0051241 , obo:GO_0065007 .
a rdfs:Class ;
rdfs:label "KIT" ;
rdfs:subClassOf obo:SO_0000704 .
obo:GO_0070278 a rdfs:Class ;
rdfs:label "extracellular matrix constituent secretion" ;
rdfs:comment "The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell." ;
rdfs:subClassOf obo:GO_0032940 .
obo:UBERON_0003851 a rdfs:Class ;
rdfs:label "diencephalon neural crest" ;
rdfs:comment "A neural crest that has_potential_to_developmentally_contribute_to a diencephalon." ;
rdfs:subClassOf obo:UBERON_0002342 .
obo:PHIPO_0000759 a rdfs:Class ;
rdfs:label "sensitive to myriocin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to myriocin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_2001212 a rdfs:Class ;
rdfs:label "regulation of vasculogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vasculogenesis." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:UBERON_0001780 a rdfs:Class ;
rdfs:label "spinal nerve" ;
rdfs:comment "The any of the paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment[MP,modified]." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:PATO_0000069 a rdfs:Class ;
rdfs:label "deviation (from_normal)" ;
rdfs:comment "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." ;
rdfs:subClassOf obo:PATO_0000068 .
obo:PHIPO_0000469 a rdfs:Class ;
rdfs:label "abnormal pathogen asexual sporulation within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host where the process of pathogen asexual sporulation, the formation of spores derived from the products of an asexual cell division, is abnormal (GO:0030436)." ;
rdfs:subClassOf obo:PHIPO_0000441 .
obo:PHIPO_0000973 a rdfs:Class ;
rdfs:label "autophagosome phenotype"@en ;
rdfs:comment "A single organism phenotype that affects a double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy (GO:0005776)." ;
rdfs:subClassOf obo:PHIPO_0000415 .
obo:GO_1905383 a rdfs:Class ;
rdfs:label "protein localization to presynapse" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a presynapse." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0035418 .
obo:UBERON_0004117 a rdfs:Class ;
rdfs:label "pharyngeal pouch" ;
rdfs:comment "An internal pocketing of pharyngeal endoderm that contacts a region of ectoderm (a pharyngeal cleft) and interdigitates in the anterior and posterior directions with the pharyngeal arches." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0003258 , obo:UBERON_0005291 .
obo:CHEBI_76841 a rdfs:Class ;
rdfs:label "EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor" ;
rdfs:comment "An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using NADH or NADPH as one donor (EC 1.14.13.*)." ;
rdfs:subClassOf obo:CHEBI_76741 .
obo:CHEBI_73181 a rdfs:Class ;
rdfs:label "EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor" ;
rdfs:comment "An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11)." ;
rdfs:subClassOf obo:CHEBI_75381 .
obo:GO_0099643 a rdfs:Class ;
rdfs:label "signal release from synapse" ;
rdfs:comment "Any signal release from a synapse." ;
rdfs:subClassOf obo:GO_0023061 .
obo:GO_0003015 a rdfs:Class ;
rdfs:label "heart process" ;
rdfs:comment "A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." ;
rdfs:subClassOf obo:GO_0003013 .
obo:UBERON_0001103 a rdfs:Class ;
rdfs:label "diaphragm" ;
rdfs:comment "A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control." ;
rdfs:subClassOf obo:UBERON_0003830 , obo:UBERON_0003831 .
obo:GO_0070126 a rdfs:Class ;
rdfs:label "mitochondrial translational termination" ;
rdfs:comment "The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa)." ;
rdfs:subClassOf obo:GO_0006415 .
obo:GO_0120032 a rdfs:Class ;
rdfs:label "regulation of plasma membrane bounded cell projection assembly" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly." ;
rdfs:subClassOf obo:GO_0060491 , obo:GO_0065007 , obo:GO_0120035 .
obo:CHEBI_72581 a rdfs:Class ;
rdfs:label "rotenones" ;
rdfs:comment "Members of the class of rotenoid which consists of a 6a,12a-dihydrochromeno[3,4-b]chromen-12(6H)-one skeleton and its substituted products." ;
rdfs:subClassOf obo:CHEBI_3992 , obo:CHEBI_71543 .
obo:CL_0000498 a rdfs:Class ;
rdfs:label "inhibitory interneuron" ;
rdfs:comment "An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS)." ;
rdfs:subClassOf obo:CL_0000099 .
obo:GO_0009605 a rdfs:Class ;
rdfs:label "response to external stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." ;
rdfs:subClassOf obo:GO_0050896 .
obo:GO_0061154 a rdfs:Class ;
rdfs:label "endothelial tube morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." ;
rdfs:subClassOf obo:GO_0003159 , obo:GO_0009653 , obo:GO_0060562 .
obo:PHIPO_0000129 a rdfs:Class ;
rdfs:label "normal asexual reproductive structure development"@en ;
rdfs:comment "A single species phenotype where the asexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is normal (GO:0048608)." ;
rdfs:subClassOf obo:PHIPO_0000045 .
obo:GO_0006412 a rdfs:Class ;
rdfs:label "translation" ;
rdfs:comment "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0009059 , obo:GO_0019538 .
obo:PHIPO_0000087 a rdfs:Class ;
rdfs:label "obsolete normal binary fission" .
obo:CHEBI_25633 a rdfs:Class ;
rdfs:label "octadecatrienoic acid" ;
rdfs:comment "Any trienoic fatty acid having eighteen carbons." ;
rdfs:subClassOf obo:CHEBI_132502 , obo:CHEBI_15904 , obo:CHEBI_59202 .
obo:UBERON_0014530 a rdfs:Class ;
rdfs:label "white matter lamina of neuraxis" ;
rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0022303 .
obo:CL_0000593 a rdfs:Class ;
rdfs:label "androgen secreting cell" ;
rdfs:comment "A steroid hormone secreting cell that secretes androgen." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000174 .
obo:CHEBI_41948 a rdfs:Class ;
rdfs:label "eflornithine" ;
rdfs:comment "A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2." ;
rdfs:subClassOf obo:CHEBI_24068 , obo:CHEBI_33704 , obo:CHEBI_60911 .
obo:CHEBI_77746 a rdfs:Class ;
rdfs:label "human metabolite" ;
rdfs:comment "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." ;
rdfs:subClassOf obo:CHEBI_75768 .
obo:GO_0050878 a rdfs:Class ;
rdfs:label "regulation of body fluid levels" ;
rdfs:comment "Any process that modulates the levels of body fluids." ;
rdfs:subClassOf obo:GO_0065008 .
obo:UBERON_0009117 a rdfs:Class ;
rdfs:label "indifferent gonad" ;
rdfs:comment "A gonad prior to differentiating into a definitive testis or ovary." ;
rdfs:subClassOf obo:UBERON_0000991 .
obo:CHEBI_17154 a rdfs:Class ;
rdfs:label "nicotinamide" ;
rdfs:comment "A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group." ;
rdfs:subClassOf obo:CHEBI_176839 , obo:CHEBI_25529 , obo:CHEBI_26416 , obo:CHEBI_26420 .
obo:CHEBI_33664 a rdfs:Class ;
rdfs:label "monocyclic hydrocarbon" ;
rdfs:subClassOf obo:CHEBI_33663 .
obo:GO_0060945 a rdfs:Class ;
rdfs:label "cardiac neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0035051 , obo:GO_0048934 .
obo:CHEBI_35436 a rdfs:Class ;
rdfs:label "D-glucoside" ;
rdfs:comment "Any glucoside in which the glycoside group is derived from D-glucose." ;
rdfs:subClassOf obo:CHEBI_24278 .
obo:PR_000001023 a rdfs:Class ;
rdfs:label "neural cell adhesion molecule NCAM" ;
rdfs:comment "A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration." ;
rdfs:subClassOf obo:PR_000001022 .
obo:GO_0042641 a rdfs:Class ;
rdfs:label "actomyosin" ;
rdfs:comment "Any complex of actin, myosin, and accessory proteins." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0061193 a rdfs:Class ;
rdfs:label "taste bud development" ;
rdfs:comment "The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors." ;
rdfs:subClassOf obo:GO_0007423 , obo:GO_0048856 .
obo:CHEBI_83781 a rdfs:Class ;
rdfs:label "(R)-tebuconazole" ;
rdfs:comment "The (R)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol." ;
rdfs:subClassOf obo:CHEBI_83779 .
obo:GO_0010948 a rdfs:Class ;
rdfs:label "negative regulation of cell cycle process" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0045786 , obo:GO_0065007 .
obo:GO_0005879 a rdfs:Class ;
rdfs:label "axonemal microtubule" ;
rdfs:comment "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." ;
rdfs:subClassOf obo:GO_0005874 , obo:GO_0005881 .
obo:PHIPO_0000092 a rdfs:Class ;
rdfs:label "obsolete abnormal binary fission" .
obo:GO_0099074 a rdfs:Class ;
rdfs:label "mitochondrion to lysosome vesicle-mediated transport" ;
rdfs:comment "Vesicle-mediated transport of cargo from the mitochondrion to the lysosome, mediated by a mitochondrion-derived vesicle." ;
rdfs:subClassOf obo:GO_0006839 , obo:GO_0007041 , obo:GO_0010496 , obo:GO_0016192 , obo:GO_0099075 .
obo:GO_1900148 a rdfs:Class ;
rdfs:label "negative regulation of Schwann cell migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900147 , obo:GO_1903976 .
obo:CL_4301592 a rdfs:Class ;
rdfs:label "Astro-TE NN_2 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Hepacam (Mmus), E330013P04Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1162 Astro-TE NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300359 .
obo:GO_0032881 a rdfs:Class ;
rdfs:label "regulation of polysaccharide metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides." ;
rdfs:subClassOf obo:GO_0006109 , obo:GO_0060255 , obo:GO_0065007 .
obo:UBERON_0000478 a rdfs:Class ;
rdfs:label "extraembryonic structure" ;
rdfs:comment "A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis." ;
rdfs:subClassOf obo:UBERON_0005423 .
obo:CHEBI_25901 a rdfs:Class ;
rdfs:label "pentose" ;
rdfs:comment "A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose)." ;
rdfs:subClassOf obo:CHEBI_35381 .
obo:GO_0043587 a rdfs:Class ;
rdfs:label "tongue morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0090596 .
obo:GO_0045653 a rdfs:Class ;
rdfs:label "negative regulation of megakaryocyte differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation." ;
rdfs:subClassOf obo:GO_0045638 , obo:GO_0045652 , obo:GO_0065007 .
obo:CHEBI_35722 a rdfs:Class .
obo:CL_0000239 a rdfs:Class ;
rdfs:label "brush border epithelial cell" ;
rdfs:comment "An epithelial cell characterized by the presence of a brush border on its apical surface, which increases the surface area for absorption." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0000075 .
obo:GO_0022035 a rdfs:Class ;
rdfs:label "rhombomere cell migration" ;
rdfs:comment "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0021535 .
obo:GO_0021638 a rdfs:Class ;
rdfs:label "trigeminal nerve formation" ;
rdfs:comment "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." ;
rdfs:subClassOf obo:GO_0021603 , obo:GO_0048646 .
obo:GO_0098981 a rdfs:Class ;
rdfs:label "cholinergic synapse" ;
rdfs:comment "A synapse that uses acetylcholine as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0045202 .
obo:UBERON_0001133 a rdfs:Class ;
rdfs:label "cardiac muscle tissue" ;
rdfs:comment "Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]." ;
rdfs:subClassOf obo:UBERON_0002036 , obo:UBERON_8600006 .
obo:GO_0042306 a rdfs:Class ;
rdfs:label "regulation of protein import into nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus." ;
rdfs:subClassOf obo:GO_0033157 , obo:GO_0046822 , obo:GO_0065007 , obo:GO_1900180 .
obo:CHEBI_39218 a rdfs:Class ;
rdfs:label "macrolide acaricide" ;
rdfs:subClassOf obo:CHEBI_39221 .
obo:GO_0072359 a rdfs:Class ;
rdfs:label "circulatory system development" ;
rdfs:comment "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:CHEBI_145947 a rdfs:Class ;
rdfs:label "antiatherosclerotic agent" ;
rdfs:comment "A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent." ;
rdfs:subClassOf obo:CHEBI_35554 .
obo:CL_4310084 a rdfs:Class ;
rdfs:label "LAMP5-CXCL14 GABA lamp5 GABAergic interneuron (Primate)" ;
rdfs:comment "A lamp5 GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:LAMP5-CXCL14 GABA." ;
rdfs:subClassOf obo:CL_4023011 .
obo:UBERON_0006925 a rdfs:Class ;
rdfs:label "digestive system gland" ;
rdfs:comment "Any gland that is part of the digestive system." ;
rdfs:subClassOf obo:UBERON_0002368 , obo:UBERON_0013765 .
obo:GO_0050670 a rdfs:Class ;
rdfs:label "regulation of lymphocyte proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lymphocyte proliferation." ;
rdfs:subClassOf obo:GO_0032944 , obo:GO_0051249 , obo:GO_0065007 .
obo:BFO_0000002 a rdfs:Class ;
rdfs:label "continuant"@en ;
rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
rdfs:subClassOf obo:BFO_0000001 .
obo:CHEBI_33248 a rdfs:Class ;
rdfs:label "hydrocarbyl group" ;
rdfs:comment "A univalent group formed by removing a hydrogen atom from a hydrocarbon." ;
rdfs:subClassOf obo:CHEBI_33249 .
obo:GO_0001829 a rdfs:Class ;
rdfs:label "trophectodermal cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0014049 a rdfs:Class ;
rdfs:label "positive regulation of glutamate secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate." ;
rdfs:subClassOf obo:GO_0014048 , obo:GO_0032892 , obo:GO_0051957 , obo:GO_0065007 , obo:GO_1903532 .
obo:GO_1903523 a rdfs:Class ;
rdfs:label "negative regulation of blood circulation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation." ;
rdfs:subClassOf obo:GO_0051241 , obo:GO_0065007 , obo:GO_1903522 .
obo:CHEBI_31011 a rdfs:Class ;
rdfs:label "valerate" ;
rdfs:comment "A short-chain fatty acid anion that is the conjugate base of valeric acid; present in ester form as component of many steroid-based pharmaceuticals." ;
rdfs:subClassOf obo:CHEBI_58951 , obo:CHEBI_58954 .
obo:UBERON_0000018 a rdfs:Class ;
rdfs:label "compound eye" ;
rdfs:comment "A light sensing organ composed of ommatidia." ;
rdfs:subClassOf obo:UBERON_0000970 , obo:UBERON_0015165 .
obo:CHEBI_73216 a rdfs:Class ;
rdfs:label "EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor" ;
rdfs:comment "Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*)." ;
rdfs:subClassOf obo:CHEBI_76759 .
obo:GO_0022403 a rdfs:Class ;
rdfs:label "cell cycle phase" ;
rdfs:comment "One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ;
rdfs:subClassOf obo:GO_0044848 .
obo:GO_0042118 a rdfs:Class ;
rdfs:label "endothelial cell activation" ;
rdfs:comment "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 .
obo:CHEBI_50492 a rdfs:Class ;
rdfs:label "thiocarbonyl compound" ;
rdfs:comment "Any compound containing the thiocarbonyl group, C=S." ;
rdfs:subClassOf obo:CHEBI_33261 .
obo:GO_0060914 a rdfs:Class ;
rdfs:label "heart formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable." ;
rdfs:subClassOf obo:GO_0048645 , obo:GO_0048646 .
obo:CL_0002453 a rdfs:Class ;
rdfs:label "oligodendrocyte precursor cell" ;
rdfs:comment "A proliferative and migratory glial progenitor cell that derives from a neural stem cell and resides within the central nervous system. It possesses the capacity to differentiate into a committed oligodendrocyte progenitor (COP) through a well-defined series of maturation steps, ultimately giving rise to a myelinating oligodendrocyte (MOL). In mice and humans, it is characterized by the expression of specific molecular markers, including Pdgfra, Cspg4 (also known as NG2) and Olig2." ;
rdfs:subClassOf obo:CL_0000123 , obo:CL_0011026 .
obo:GO_0061484 a rdfs:Class ;
rdfs:label "hematopoietic stem cell homeostasis" ;
rdfs:comment "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells." ;
rdfs:subClassOf obo:GO_0048872 .
obo:UBERON_0002084 a rdfs:Class ;
rdfs:label "heart left ventricle" ;
rdfs:comment "A cardiac ventricle that is in the left side of the heart." ;
rdfs:subClassOf obo:UBERON_0002082 , obo:UBERON_0035553 .
obo:GO_0003218 a rdfs:Class ;
rdfs:label "cardiac left ventricle formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts." ;
rdfs:subClassOf obo:GO_0003211 , obo:GO_0048646 .
obo:GO_0000070 a rdfs:Class ;
rdfs:label "mitotic sister chromatid segregation" ;
rdfs:comment "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." ;
rdfs:subClassOf obo:GO_0000819 , obo:GO_0098813 , obo:GO_1903047 .
obo:CHEBI_21656 a rdfs:Class ;
rdfs:label "N-acyl-hexosamine" ;
rdfs:subClassOf obo:CHEBI_24586 .
obo:GO_1903053 a rdfs:Class ;
rdfs:label "regulation of extracellular matrix organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of extracellular matrix organization." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0015185 a rdfs:Class ;
rdfs:label "gamma-aminobutyric acid transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA)." ;
rdfs:subClassOf obo:GO_0015171 , obo:GO_0022857 , obo:GO_0046943 .
obo:CHEBI_55324 a rdfs:Class ;
rdfs:label "gastrointestinal drug" ;
rdfs:comment "A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:PHIPO_0000409 a rdfs:Class ;
rdfs:label "transporter activity phenotype"@en ;
rdfs:comment "A phenotype that affects a transporter activity." ;
rdfs:subClassOf obo:PHIPO_0000411 .
obo:GO_0055013 a rdfs:Class ;
rdfs:label "cardiac muscle cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0055002 , obo:GO_0055006 .
obo:PHIPO_0000748 a rdfs:Class ;
rdfs:label "sensitive to daptomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to daptomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0032043 a rdfs:Class ;
rdfs:label "mitochondrial DNA catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA." ;
rdfs:subClassOf obo:GO_0006308 , obo:GO_0032042 .
obo:CHEBI_33559 a rdfs:Class ;
rdfs:label "s-block element atom" ;
rdfs:subClassOf obo:CHEBI_33250 .
obo:GO_1905492 a rdfs:Class ;
rdfs:label "positive regulation of branching morphogenesis of a nerve" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_2000172 .
obo:UBERON_0006135 a rdfs:Class ;
rdfs:label "myelinated nerve fiber" ;
rdfs:comment "Axons of neurons encased in a lipoproteinaceous material called myelin. (MeSH)." ;
rdfs:subClassOf obo:UBERON_0006134 .
obo:UBERON_0001986 a rdfs:Class ;
rdfs:label "endothelium" ;
rdfs:comment "A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0000487 , obo:UBERON_0012275 .
obo:CHEBI_36357 a rdfs:Class ;
rdfs:label "polyatomic entity" ;
rdfs:comment "Any molecular entity consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:UBERON_0004784 a rdfs:Class ;
rdfs:label "heart ventricle wall" ;
rdfs:comment "An anatomical wall that is part of a cardiac ventricle [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0037144 .
obo:CHEBI_88188 a rdfs:Class ;
rdfs:label "drug allergen" ;
rdfs:comment "Any drug which causes the onset of an allergic reaction." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_50904 .
a rdfs:Class ;
rdfs:label "ACTA2" ;
rdfs:subClassOf obo:SO_0000704 .
obo:GO_0045444 a rdfs:Class ;
rdfs:label "fat cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0042421 a rdfs:Class ;
rdfs:label "norepinephrine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0042415 , obo:GO_0042423 .
obo:UBERON_0034878 a rdfs:Class ;
rdfs:label "prechordal mesoderm" ;
rdfs:comment "The area of axial mesoderm that develops into the prechordal plate." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005423 .
obo:GO_0042923 a rdfs:Class ;
rdfs:label "neuropeptide binding" ;
rdfs:comment "Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators)." ;
rdfs:subClassOf obo:GO_0042277 .
obo:GO_2000529 a rdfs:Class ;
rdfs:label "positive regulation of myeloid dendritic cell chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000510 , obo:GO_2000527 .
obo:UBERON_0001072 a rdfs:Class ;
rdfs:label "inferior vena cava" ;
rdfs:comment "A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart." ;
rdfs:subClassOf obo:UBERON_0004087 .
obo:CHEBI_24632 a rdfs:Class ;
rdfs:label "hydrocarbon" ;
rdfs:comment "A compound consisting of carbon and hydrogen only." ;
rdfs:subClassOf obo:CHEBI_33245 .
obo:UBERON_0000007 a rdfs:Class ;
rdfs:label "pituitary gland" ;
rdfs:comment "The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]." ;
rdfs:subClassOf obo:UBERON_0002368 , obo:UBERON_0003133 , obo:UBERON_0003296 , obo:UBERON_0003937 , obo:UBERON_0004121 .
obo:GO_0021678 a rdfs:Class ;
rdfs:label "third ventricle development" ;
rdfs:comment "The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0061343 a rdfs:Class ;
rdfs:label "cell adhesion involved in heart morphogenesis" ;
rdfs:comment "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart." ;
rdfs:subClassOf obo:GO_0007155 .
obo:PR_000001012 a rdfs:Class ;
rdfs:label "integrin alpha-M" ;
rdfs:comment "An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1." ;
rdfs:subClassOf obo:PR_000001005 .
obo:CHEBI_23643 a rdfs:Class ;
rdfs:label "depsipeptide" ;
rdfs:comment "A natural or synthetic compound having a sequence of amino and hydroxy carboxylic acid residues (usually α-amino and α-hydroxy acids), commonly but not necessarily regularly alternating." ;
rdfs:subClassOf obo:CHEBI_16670 .
obo:CHEBI_32862 a rdfs:Class ;
rdfs:label "L-prolinate" ;
rdfs:comment "An optically active form of prolinate having L-configuration." ;
rdfs:subClassOf obo:CHEBI_32871 , obo:CHEBI_59814 .
obo:PHIPO_0000239 a rdfs:Class ;
rdfs:label "abnormal protein localization"@en ;
rdfs:comment "A single organism phenotype in which the localization of a protein in a cell is abnormal. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." ;
rdfs:subClassOf obo:PHIPO_0000237 , obo:PHIPO_0000929 , obo:PHIPO_0001094 .
obo:GO_0035577 a rdfs:Class ;
rdfs:label "azurophil granule membrane" ;
rdfs:comment "The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid." ;
rdfs:subClassOf obo:GO_0005765 , obo:GO_0016020 , obo:GO_0030667 .
obo:CL_0000005 a rdfs:Class ;
rdfs:label "neural crest derived fibroblast" ;
rdfs:comment "Any fibroblast that is derived from the neural crest." ;
rdfs:subClassOf obo:CL_0000057 .
obo:PHIPO_0001351 a rdfs:Class ;
rdfs:label "normal growth on itraconazole"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to itraconazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_83811 a rdfs:Class ;
rdfs:label "proteinogenic amino acid derivative" ;
rdfs:comment "Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom." ;
rdfs:subClassOf obo:CHEBI_83821 .
obo:GO_0061046 a rdfs:Class ;
rdfs:label "regulation of branching involved in lung morphogenesis" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." ;
rdfs:subClassOf obo:GO_0060688 , obo:GO_0065007 , obo:GO_1905330 .
obo:CHEBI_37578 a rdfs:Class ;
rdfs:label "halide" ;
rdfs:comment "Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements." ;
rdfs:subClassOf obo:CHEBI_24471 , obo:CHEBI_37577 .
obo:UBERON_0003307 a rdfs:Class ;
rdfs:label "floor plate of midbrain" ;
rdfs:comment "A floor plate that is part of a midbrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0002616 , obo:UBERON_0003306 .
obo:PHIPO_0000520 a rdfs:Class ;
rdfs:label "resistance to florfenicol"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to florfenicol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0061519 a rdfs:Class ;
rdfs:label "macrophage homeostasis" ;
rdfs:comment "The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." ;
rdfs:subClassOf obo:GO_0001776 , obo:GO_0002262 , obo:GO_0048872 .
obo:UBERON_0003914 a rdfs:Class ;
rdfs:label "epithelial tube" ;
rdfs:comment "Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." ;
rdfs:subClassOf obo:UBERON_0000025 , obo:UBERON_0000483 .
obo:CHEBI_64775 a rdfs:Class ;
rdfs:label "organic anionic group" ;
rdfs:comment "An anionic group that contains carbon." ;
rdfs:subClassOf obo:CHEBI_64767 .
obo:PHIPO_0001259 a rdfs:Class ;
rdfs:label "host cell viability with pathogen phenotype"@en ;
rdfs:comment "A pathogen host interaction cell level phenotype which affects the viability of a host cell in the presence of a pathogen." ;
rdfs:subClassOf obo:PHIPO_0000510 .
obo:GO_0042996 a rdfs:Class ;
rdfs:label "regulation of Golgi to plasma membrane protein transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." ;
rdfs:subClassOf obo:GO_0051223 , obo:GO_0060627 , obo:GO_0065007 , obo:GO_1903076 .
obo:PHIPO_0000174 a rdfs:Class ;
rdfs:label "obsolete decreased pathogen host interaction RNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is decreased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:CL_0000540 a rdfs:Class ;
rdfs:label "neuron" ;
rdfs:comment "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." ;
rdfs:subClassOf obo:CL_0000393 , obo:CL_0000404 , obo:CL_0002319 .
obo:GO_1904699 a rdfs:Class ;
rdfs:label "positive regulation of acinar cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of acinar cell proliferation." ;
rdfs:subClassOf obo:GO_0050679 , obo:GO_0065007 , obo:GO_1904697 .
obo:PHIPO_0000438 a rdfs:Class ;
rdfs:label "altered substrate specificity"@en ;
rdfs:comment "A single species molecular function phenotype in which the substrate specificity of a catalytic activity differs from wild type." ;
rdfs:subClassOf obo:PHIPO_0000434 .
obo:CHEBI_85251 a rdfs:Class ;
rdfs:label "teicoplanin A2-2" ;
rdfs:comment "A teicoplanin A2 that has 8-methylnonanoyl as the variable N-acyl group." ;
rdfs:subClassOf obo:CHEBI_34994 .
obo:GO_0061533 a rdfs:Class ;
rdfs:label "norepinephrine secretion, neurotransmission" ;
rdfs:comment "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0007269 , obo:GO_0048243 , obo:GO_0160043 .
obo:CL_0020003 a rdfs:Class ;
rdfs:label "internal globus pallidus core projecting neuron" ;
rdfs:comment "A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi) of primates, in the central “core” region. It expresses parvalbumin, is primarily GABAergic, and projects to motor thalamic nuclei including the ventral anterior, ventrolateral, and ventromedial nuclei. In the rodent homolog (entopeduncular nucleus), the core subregion is characterized by concentrated parvalbumin-positive neurons targeting the ventral anterior-ventral lateral thalamic nucleus and receives inputs from the dorsolateral striatum innervated by sensorimotor cortices (Miyamoto & Fukuda, 2022). This neuron corresponds to the sensorimotor output population of the GPi, as demonstrated in human tissue and cross-species comparative studies (Wallace et al., 2017) and by classic tracing in primates (Parent & De Bellefeuille, 1982; Parent et al., 2001)." ;
rdfs:subClassOf obo:CL_0000617 , obo:CL_0012001 .
obo:UBERON_0000390 a rdfs:Class ;
rdfs:label "lens nucleus" ;
rdfs:comment "The core of the crystalline lens, surrounded by the cortex." ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0034944 .
obo:PHIPO_0000623 a rdfs:Class ;
rdfs:label "resistance to bifonazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to bifonazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_0000377 a rdfs:Class ;
rdfs:label "tracheoblast" ;
rdfs:subClassOf obo:CL_0000069 .
obo:PR_000001551 a rdfs:Class ;
rdfs:label "relaxin family peptide receptor protein" ;
rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human RXFP1 to RXFP4 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds relaxins." ;
rdfs:subClassOf obo:PR_000001094 .
obo:GO_0061549 a rdfs:Class ;
rdfs:label "sympathetic ganglion development" ;
rdfs:comment "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0061548 .
obo:CHEBI_29256 a rdfs:Class ;
rdfs:label "thiol" ;
rdfs:comment "An organosulfur compound in which a thiol group, ‒SH, is attached to a carbon atom of any aliphatic or aromatic moiety." ;
rdfs:subClassOf obo:CHEBI_33261 .
obo:PATO_0070047 a rdfs:Class ;
rdfs:label "polychromatophilic" ;
rdfs:comment "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions." ;
rdfs:subClassOf obo:PATO_0070045 .
obo:PHIPO_0001357 a rdfs:Class ;
rdfs:label "sensitive to fluopyram" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fluopyram. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PATO_0002324 a rdfs:Class ;
rdfs:label "offset quality" ;
rdfs:comment "The temporal relation between the end of the process with respect to a reference process." ;
rdfs:subClassOf obo:PATO_0002323 .
obo:CHEBI_59202 a rdfs:Class ;
rdfs:label "straight-chain fatty acid" ;
rdfs:comment "Any fatty acid whose skeletal carbon atoms form an unbranched open chain." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:PHIPO_0000579 a rdfs:Class ;
rdfs:label "resistance to rotenone"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to rotenone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_2000648 a rdfs:Class ;
rdfs:label "positive regulation of stem cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of stem cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0065007 , obo:GO_0072091 .
obo:GO_0043226 a rdfs:Class ;
rdfs:label "organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0110165 .
obo:PHIPO_0001391 a rdfs:Class ;
rdfs:label "resistance to metconazole" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to metconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0013704 a rdfs:Class ;
rdfs:label "notochordal canal" ;
rdfs:comment "A tubular passage that extends from the primitive pit into the head process during the early stages of embryonic development in mammals. It perforates the splanchnopleure layer so that the yolk sac and the amnion are connected temporarily." ;
rdfs:subClassOf obo:UBERON_0004111 .
obo:GO_0060591 a rdfs:Class ;
rdfs:label "chondroblast differentiation" ;
rdfs:comment "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0023057 a rdfs:Class ;
rdfs:label "negative regulation of signaling" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." ;
rdfs:subClassOf obo:GO_0023051 , obo:GO_0048519 , obo:GO_0065007 .
obo:GO_0046669 a rdfs:Class ;
rdfs:label "regulation of compound eye retinal cell programmed cell death" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." ;
rdfs:subClassOf obo:GO_0046668 , obo:GO_0065007 .
obo:UBERON_0035639 a rdfs:Class ;
rdfs:label "ocular adnexa" ;
rdfs:comment "The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva." ;
rdfs:subClassOf obo:UBERON_0034921 .
obo:GO_0060043 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0055021 , obo:GO_0065007 .
obo:GO_1903747 a rdfs:Class ;
rdfs:label "regulation of protein localization to mitochondrion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to mitochondrion." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_0061554 a rdfs:Class ;
rdfs:label "ganglion formation" ;
rdfs:comment "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0070125 a rdfs:Class ;
rdfs:label "mitochondrial translational elongation" ;
rdfs:comment "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion." ;
rdfs:subClassOf obo:GO_0006414 .
obo:CL_1000465 a rdfs:Class ;
rdfs:label "chromaffin cell of ovary" ;
rdfs:comment "A chromaffin cell that is part of the ovary." ;
rdfs:subClassOf obo:CL_0000166 .
obo:PHIPO_0001084 a rdfs:Class ;
rdfs:label "increased unicellular population growth rate"@en ;
rdfs:comment "A single species population growth phenotype where the rate of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is faster than normal." ;
rdfs:subClassOf obo:PHIPO_0000975 .
obo:GO_0055006 a rdfs:Class ;
rdfs:label "cardiac cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:GO_0003314 a rdfs:Class ;
rdfs:label "heart rudiment morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the heart rudiment are generated and organized." ;
rdfs:subClassOf obo:GO_0002009 , obo:GO_0009653 , obo:GO_0048598 .
obo:UBERON_0001874 a rdfs:Class ;
rdfs:label "putamen" ;
rdfs:comment "Subcortical nucleus of telencephalic , which together with the caudate nucleus, forms the striatum. The putamen lies lateral to the internal capsule and medial to the external medullary lamina, and is separated from the caudate nucleus by the fibers of the internal capsule for most of its length, except at its anterior portion." ;
rdfs:subClassOf obo:UBERON_0009663 .
obo:PR_P19437 a rdfs:Class ;
rdfs:label "B-lymphocyte antigen CD20 (mouse)" ;
rdfs:comment "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001289 , obo:PR_000029032 .
obo:CL_0002610 a rdfs:Class ;
rdfs:label "raphe nuclei neuron" ;
rdfs:comment "A neuron of the raphe nuclei." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000029 .
obo:PATO_0002226 a rdfs:Class ;
rdfs:label "subcylindrical" ;
rdfs:comment "A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical." ;
rdfs:subClassOf obo:PATO_0001873 .
obo:GO_0006538 a rdfs:Class ;
rdfs:label "L-glutamate catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of L-glutamate." ;
rdfs:subClassOf obo:GO_0006536 , obo:GO_0009056 , obo:GO_0043649 , obo:GO_0170035 , obo:GO_0170040 .
obo:PR_000005444 a rdfs:Class ;
rdfs:label "chondrolectin" ;
rdfs:comment "A protein that is a translation product of the human CHODL gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PHIPO_0000076 a rdfs:Class ;
rdfs:label "altered in pigment accumulation in asexual spore"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of coloring matter in an asexual spore cell is altered." ;
rdfs:subClassOf obo:PHIPO_0000285 .
obo:CHEBI_78692 a rdfs:Class ;
rdfs:label "1-[biphenyl-4-yl(phenyl)methyl]imidazole" ;
rdfs:comment "A member of the class of imidazoles carrying an α-(biphenyl-4-yl)benzyl substituent at position 1." ;
rdfs:subClassOf obo:CHEBI_22888 , obo:CHEBI_24780 .
obo:CHEBI_73537 a rdfs:Class ;
rdfs:label "1,8-naphthyridine derivative" ;
rdfs:comment "Any naphthyridine derivative that is a derivative of 1,8-naphthyridine." ;
rdfs:subClassOf obo:CHEBI_73539 .
obo:GO_1902877 a rdfs:Class ;
rdfs:label "positive regulation of embryonic pattern specification" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of embryonic pattern specification." ;
rdfs:subClassOf obo:GO_0051240 , obo:GO_0065007 , obo:GO_1902875 .
obo:CL_4310134 a rdfs:Class ;
rdfs:label "STRd D2 Striosome MSN striosomal D2 medium spiny neuron (Primate)" ;
rdfs:comment "A striosomal D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 Striosome MSN." ;
rdfs:subClassOf obo:CL_4030049 , obo:CL_4310059 .
obo:GO_0003253 a rdfs:Class ;
rdfs:label "cardiac neural crest cell migration involved in outflow tract morphogenesis" ;
rdfs:comment "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract." ;
rdfs:subClassOf obo:GO_0001755 , obo:GO_0060973 .
obo:CL_4307089 a rdfs:Class ;
rdfs:label "OPC NN_1 Col27a1 oligodendrocyte precursor cell (Mmus)" ;
rdfs:comment "A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Col27a1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Col27a1. These cells are located in the Midbrain, Pons, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5269 OPC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300366 .
obo:CHEBI_18375 a rdfs:Class ;
rdfs:label "nucleoside 3',5'-cyclic phosphate" ;
rdfs:comment "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-3 and C-5 of the ribose ring are engaged in formation of a cyclic mono-, di-, tri- or tetra-phosphate." ;
rdfs:subClassOf obo:CHEBI_23447 .
obo:GO_0099187 a rdfs:Class ;
rdfs:label "presynaptic cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton." ;
rdfs:subClassOf obo:GO_0007010 , obo:GO_0009987 .
obo:GO_0033686 a rdfs:Class ;
rdfs:label "positive regulation of luteinizing hormone secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone." ;
rdfs:subClassOf obo:GO_0032278 , obo:GO_0033684 , obo:GO_0065007 .
obo:CHEBI_34997 a rdfs:Class ;
rdfs:label "teicoplanin A2-4" ;
rdfs:comment "A teicoplanin A2 that has 8-methyldecanoyl as the variable N-acyl group." ;
rdfs:subClassOf obo:CHEBI_34994 , obo:CHEBI_60911 .
obo:CL_0009001 a rdfs:Class ;
rdfs:label "compound eye retinal cell" ;
rdfs:comment "Any cell in the compound eye, a light sensing organ composed of ommatidia." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0009004 .
obo:CL_0020006 a rdfs:Class ;
rdfs:label "OB-Dopa-GABA" ;
rdfs:comment "A transcriptomically defined GABAergic neuron coexpressing dopamine located in the olfactory bulb and part of the striatum." ;
rdfs:subClassOf obo:CL_0000617 , obo:CL_0000700 , obo:CL_0002613 .
obo:PHIPO_0000984 a rdfs:Class ;
rdfs:label "normal meiotic cell cycle"@en ;
rdfs:comment "A reproductive process phenotype in which a cell proceeds normally through a meiotic cell cycle (GO:0051321)." ;
rdfs:subClassOf obo:PHIPO_0000046 .
obo:PHIPO_0000557 a rdfs:Class ;
rdfs:label "resistance to myriocin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to myriocin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0015178 a rdfs:Class ;
rdfs:label "somite border" ;
rdfs:comment "A region of somite adjacent to presomitic mesoderm." ;
rdfs:subClassOf obo:UBERON_0007651 .
obo:UBERON_0034873 a rdfs:Class ;
rdfs:label "bodily gas" ;
rdfs:comment "Any substance in the body or expelled from the body that is in a gaseous state." ;
rdfs:subClassOf obo:UBERON_0000463 .
obo:GO_0060539 a rdfs:Class ;
rdfs:label "diaphragm development" ;
rdfs:comment "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060538 .
obo:GO_0098523 a rdfs:Class ;
rdfs:label "neuromuscular junction of myotube" ;
rdfs:comment "A neuromuscular junction in which the target muscle cell is a myotube." ;
rdfs:subClassOf obo:GO_0031594 , obo:GO_0045202 .
obo:CHEBI_36961 a rdfs:Class ;
rdfs:label "chalcocarbonic acid" ;
rdfs:subClassOf obo:CHEBI_36962 .
obo:UBERON_0005398 a rdfs:Class ;
rdfs:label "female reproductive gland" ;
rdfs:comment "A sex gland that is part of a female reproductive system." ;
rdfs:subClassOf obo:UBERON_0003937 .
obo:CHEBI_48354 a rdfs:Class ;
rdfs:label "polar solvent" ;
rdfs:comment "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." ;
rdfs:subClassOf obo:CHEBI_46787 .
obo:GO_0040013 a rdfs:Class ;
rdfs:label "negative regulation of locomotion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." ;
rdfs:subClassOf obo:GO_0040012 , obo:GO_0048519 , obo:GO_0065007 .
obo:PHIPO_0000308 a rdfs:Class ;
rdfs:label "obsolete normal effector of pathogenicity activation of host defense" ;
rdfs:comment "The host defenses activated by the pathogen are unaltered compared to the wild type interaction" .
a rdfs:Class ;
rdfs:label "LAMP5" ;
rdfs:subClassOf obo:SO_0000704 .
obo:PR_000001327 a rdfs:Class ;
rdfs:label "cadherin" ;
rdfs:comment "A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0010363 a rdfs:Class ;
rdfs:label "regulation of plant-type hypersensitive response" ;
rdfs:comment "Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0045088 , obo:GO_0065007 , obo:GO_0080135 .
obo:GO_0042254 a rdfs:Class ;
rdfs:label "ribosome biogenesis" ;
rdfs:comment "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis." ;
rdfs:subClassOf obo:GO_0022613 .
obo:GO_1903698 a rdfs:Class ;
rdfs:label "positive regulation of microvillus assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of microvillus assembly." ;
rdfs:subClassOf obo:GO_0032534 , obo:GO_0065007 , obo:GO_0120034 .
obo:PATO_0001552 a rdfs:Class ;
rdfs:label "decreased sensitivity of a process" ;
rdfs:comment "A sensitivity of a process which is lower than normal or average." ;
rdfs:subClassOf obo:PATO_0001457 , obo:PATO_0002302 .
obo:GO_0016043 a rdfs:Class ;
rdfs:label "cellular component organization" ;
rdfs:comment "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0071840 .
obo:GO_0070663 a rdfs:Class ;
rdfs:label "regulation of leukocyte proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of leukocyte proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:PR_000015658 a rdfs:Class ;
rdfs:label "SCO-spondin" ;
rdfs:comment "A protein that is a translation product of the human SSPO gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_1905880 a rdfs:Class ;
rdfs:label "negative regulation of oogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1905879 , obo:GO_2000242 .
obo:GO_0048514 a rdfs:Class ;
rdfs:label "blood vessel morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0035239 .
obo:GO_0060921 a rdfs:Class ;
rdfs:label "sinoatrial node cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0060920 .
obo:CL_0002464 a rdfs:Class ;
rdfs:label "SIRPa-negative adipose dendritic cell" ;
rdfs:comment "An adipose dendritic cell that is SIRPa-negative." ;
rdfs:subClassOf obo:CL_0000990 , obo:CL_0002462 .
obo:PHIPO_0001059 a rdfs:Class ;
rdfs:label "increased level of pyocyanin"@en ;
rdfs:comment "A single species cell phenotype in which the amount of pyocyanin measured in a cell is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001037 .
obo:CL_4306426 a rdfs:Class ;
rdfs:label "pinealocyte (Mmus)" ;
rdfs:comment "A pinealocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cngb3 (Mmus), Ush2a (Mmus). It is glutamatergic (inferred from expression of Ddc, Slc17a6, Slc17a7). These cells are located in the brain , in or close to the regions: third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:4606 Pineal Crx Glut_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000652 .
obo:GO_0051970 a rdfs:Class ;
rdfs:label "negative regulation of transmission of nerve impulse" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." ;
rdfs:subClassOf obo:GO_0010648 , obo:GO_0031645 , obo:GO_0051969 , obo:GO_0065007 .
obo:GO_0060978 a rdfs:Class ;
rdfs:label "angiogenesis involved in coronary vascular morphogenesis" ;
rdfs:comment "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels." ;
rdfs:subClassOf obo:GO_0001525 .
obo:GO_1902884 a rdfs:Class ;
rdfs:label "positive regulation of response to oxidative stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of response to oxidative stress." ;
rdfs:subClassOf obo:GO_0048584 , obo:GO_0065007 , obo:GO_1902882 .
obo:PHIPO_0000735 a rdfs:Class ;
rdfs:label "sensitive to cefotaxime"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefotaxime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0002608 a rdfs:Class ;
rdfs:label "negative regulation of myeloid dendritic cell antigen processing and presentation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002605 , obo:GO_0002607 , obo:GO_0065007 .
obo:GO_0060431 a rdfs:Class ;
rdfs:label "primary lung bud formation" ;
rdfs:comment "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds." ;
rdfs:subClassOf obo:GO_0016331 , obo:GO_0048645 , obo:GO_0048646 , obo:GO_0060441 , obo:GO_0060572 .
obo:UBERON_0001593 a rdfs:Class ;
rdfs:label "venous plexus" ;
rdfs:comment "A congregation of multiple veins." ;
rdfs:subClassOf obo:UBERON_0004537 , obo:UBERON_0005629 .
obo:CHEBI_38314 a rdfs:Class ;
rdfs:label "pyrazines" ;
rdfs:subClassOf obo:CHEBI_38313 .
obo:GO_0060632 a rdfs:Class ;
rdfs:label "regulation of microtubule-based movement" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0032886 , obo:GO_0065007 .
obo:GO_0010633 a rdfs:Class ;
rdfs:label "negative regulation of epithelial cell migration" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration." ;
rdfs:subClassOf obo:GO_0010632 , obo:GO_0030336 , obo:GO_0051241 , obo:GO_0065007 .
obo:GO_2000547 a rdfs:Class ;
rdfs:label "regulation of dendritic cell dendrite assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120032 .
obo:CL_0002246 a rdfs:Class ;
rdfs:label "peripheral blood stem cell" ;
rdfs:comment "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells)." ;
rdfs:subClassOf obo:CL_0000037 , obo:CL_0000080 .
obo:CHEBI_50011 a rdfs:Class ;
rdfs:label "Calcofluor White" ;
rdfs:subClassOf obo:CHEBI_38700 .
obo:CL_0002479 a rdfs:Class ;
rdfs:label "F4/80-positive adipose macrophage" ;
rdfs:comment "An adipose macrophage that does not express MHC-II but is F4/80-positive." ;
rdfs:subClassOf obo:CL_0002477 .
obo:GO_0002708 a rdfs:Class ;
rdfs:label "positive regulation of lymphocyte mediated immunity" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity." ;
rdfs:subClassOf obo:GO_0002705 , obo:GO_0002706 , obo:GO_0065007 .
obo:PHIPO_0000141 a rdfs:Class ;
rdfs:label "decreased extent and duration of protein-protein interaction"@en ;
rdfs:comment "A single species molecular function phenotype in which the binding of one protein to another occurs to a lower extent, and for a shorter time, than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000133 .
obo:CL_0000527 a rdfs:Class ;
rdfs:label "efferent neuron" ;
rdfs:comment "A neuron which sends impulses peripherally to activate muscles or secretory cells." ;
rdfs:subClassOf obo:CL_0000540 .
obo:CHEBI_83403 a rdfs:Class ;
rdfs:label "monochlorobenzenes" ;
rdfs:comment "Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine." ;
rdfs:subClassOf obo:CHEBI_23132 .
obo:CHEBI_23443 a rdfs:Class ;
rdfs:label "cyclic amide" ;
rdfs:subClassOf obo:CHEBI_32988 .
obo:CHEBI_35845 a rdfs:Class ;
rdfs:label "gout suppressant" ;
rdfs:comment "A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout." ;
rdfs:subClassOf obo:CHEBI_35842 .
obo:GO_0002686 a rdfs:Class ;
rdfs:label "negative regulation of leukocyte migration" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration." ;
rdfs:subClassOf obo:GO_0002683 , obo:GO_0002685 , obo:GO_0030336 , obo:GO_0065007 .
obo:GO_0061024 a rdfs:Class ;
rdfs:label "membrane organization" ;
rdfs:comment "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." ;
rdfs:subClassOf obo:GO_0016043 .
obo:GO_0021643 a rdfs:Class ;
rdfs:label "vagus nerve maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." ;
rdfs:subClassOf obo:GO_0021605 , obo:GO_0021700 .
obo:CHEBI_23378 a rdfs:Class ;
rdfs:label "copper cation" ;
rdfs:subClassOf obo:CHEBI_33515 , obo:CHEBI_37404 .
obo:CL_0002095 a rdfs:Class ;
rdfs:label "hilus cell of ovary" ;
rdfs:comment "A cell in the hilum of the ovary that produces androgens." ;
rdfs:subClassOf obo:CL_0000593 , obo:CL_0002132 .
obo:GO_0016755 a rdfs:Class ;
rdfs:label "aminoacyltransferase activity" ;
rdfs:comment "Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor)." ;
rdfs:subClassOf obo:GO_0016746 .
obo:PHIPO_0000546 a rdfs:Class ;
rdfs:label "resistance to cefotetan"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cefotetan. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_33462 a rdfs:Class ;
rdfs:label "phosphonate(1-)" ;
rdfs:comment "A monovalent inorganic anion obtained by deprotonation of one of the two OH groups in phosphonic acid." ;
rdfs:subClassOf obo:CHEBI_33461 , obo:CHEBI_79389 .
obo:GO_0042995 a rdfs:Class ;
rdfs:label "cell projection" ;
rdfs:comment "A prolongation or process extending from a cell, e.g. a flagellum or axon." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0016358 a rdfs:Class ;
rdfs:label "dendrite development" ;
rdfs:comment "The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0031175 , obo:GO_0048856 .
obo:UBERON_0007829 a rdfs:Class ;
rdfs:label "pectoral girdle bone" ;
rdfs:comment "A bone that is part of a pectoral girdle region." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0007828 , obo:UBERON_0010741 .
obo:GO_0071873 a rdfs:Class ;
rdfs:label "response to norepinephrine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_0071869 .
obo:PR_P16872 a rdfs:Class ;
rdfs:label "interleukin-7 receptor subunit alpha (mouse)" ;
rdfs:comment "An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001869 , obo:PR_000029032 .
obo:GO_0007601 a rdfs:Class ;
rdfs:label "visual perception" ;
rdfs:comment "The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image." ;
rdfs:subClassOf obo:GO_0050953 .
obo:PHIPO_0001339 a rdfs:Class ;
rdfs:label "sensitive to procymidone"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to procymidone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0007218 a rdfs:Class ;
rdfs:label "neuropeptide signaling pathway" ;
rdfs:comment "A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process." ;
rdfs:subClassOf obo:GO_0007186 .
obo:UBERON_0000013 a rdfs:Class ;
rdfs:label "sympathetic nervous system" ;
rdfs:comment "The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:GO_0009880 a rdfs:Class ;
rdfs:label "embryonic pattern specification" ;
rdfs:comment "The process that results in the patterns of cell differentiation that will arise in an embryo." ;
rdfs:subClassOf obo:GO_0007389 .
obo:PHIPO_0001458 a rdfs:Class ;
rdfs:label "reduced susceptibility to pathogen"@en ;
rdfs:comment "A quality of an organism describing a decreased proneness to infection, colonization, or disease development following exposure to a pathogen relative to a reference organism or population under equivalent conditions." ;
rdfs:subClassOf obo:PHIPO_0001456 .
obo:PHIPO_0000243 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction protein localization to nucleus" ;
rdfs:comment "A pathogen host interaction phenotype in which the localization of a protein to the nucleus is abnormal. (Which nucleus? pathogen or host?)" .
obo:PR_000001786 a rdfs:Class ;
rdfs:label "prominin-1" ;
rdfs:comment "A prominin that is a translation product of the human PROM1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001785 .
obo:CHEBI_77047 a rdfs:Class ;
rdfs:label "tylosin(1+)" ;
rdfs:comment "An organic cation that is the conjugate acid of tylosin, obtained by protonation of the tertiary amino group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_1901220 a rdfs:Class ;
rdfs:label "negative regulation of cardiac chamber morphogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0065007 , obo:GO_1901219 .
obo:GO_0003245 a rdfs:Class ;
rdfs:label "cardiac muscle tissue growth involved in heart morphogenesis" ;
rdfs:comment "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart." ;
rdfs:subClassOf obo:GO_0003241 , obo:GO_0055017 .
obo:GO_0098934 a rdfs:Class ;
rdfs:label "retrograde dendritic transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0098935 .
obo:CHEBI_70977 a rdfs:Class ;
rdfs:label "alkane-alpha,omega-diammonium(2+)" ;
rdfs:comment "An organic cation obtained by protonation of the amino groups of any alkane-α,ω-diamine; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_0002274 a rdfs:Class ;
rdfs:label "myeloid leukocyte activation" ;
rdfs:comment "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0045321 .
obo:GO_0060457 a rdfs:Class ;
rdfs:label "negative regulation of digestive system process" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0044058 , obo:GO_0051241 , obo:GO_0065007 .
obo:PHIPO_0000951 a rdfs:Class ;
rdfs:label "pathogen growth within host phenotype"@en ;
rdfs:comment "A pathogen host phenotype which affects the vegetative growth or proliferation of the pathogen inside the host (e.g. after entry by penetration or infiltration)." ;
rdfs:subClassOf obo:PHIPO_0000332 .
obo:CHEBI_27314 a rdfs:Class ;
rdfs:label "water-soluble vitamin (role)" ;
rdfs:comment "Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine." ;
rdfs:subClassOf obo:CHEBI_33229 .
obo:GO_0070131 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial translation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ;
rdfs:subClassOf obo:GO_0045727 , obo:GO_0065007 , obo:GO_0070129 .
obo:GO_0030316 a rdfs:Class ;
rdfs:label "osteoclast differentiation" ;
rdfs:comment "The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue." ;
rdfs:subClassOf obo:GO_0002573 , obo:GO_0030154 .
obo:CHEBI_4811 a rdfs:Class ;
rdfs:label "epoxiconazole" ;
rdfs:comment "A racemate composed of equimolar amounts of (2S,3R)- and (2R,3S)-epoxiconazole. A broad-spectrum fungicide for control of diseases caused by Ascomycetes, Basidiomycetes and Deuteromycetes. Epoxiconazole is moderately toxic to birds, honeybees, earthworms and most aquatic organisms." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87067 , obo:CHEBI_87100 .
obo:GO_0072698 a rdfs:Class ;
rdfs:label "protein localization to microtubule cytoskeleton" ;
rdfs:comment "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0044380 .
obo:UBERON_0004128 a rdfs:Class ;
rdfs:label "optic vesicle" ;
rdfs:comment "The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]." ;
rdfs:subClassOf obo:UBERON_0000479 , obo:UBERON_0004121 .
obo:CHEBI_26761 a rdfs:Class ;
rdfs:label "steroid antibiotic" ;
rdfs:subClassOf obo:CHEBI_35341 , obo:CHEBI_49319 .
obo:UBERON_0010360 a rdfs:Class ;
rdfs:label "pharyngeal arch mesenchyme from head mesenchyme" ;
rdfs:comment "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a entire pharyngeal arch associated mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0004120 , obo:UBERON_0005291 .
obo:UBERON_0003570 a rdfs:Class ;
rdfs:label "respiratory system connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:GO_1904204 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle hypertrophy" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy." ;
rdfs:subClassOf obo:GO_0014733 , obo:GO_0014743 , obo:GO_0065007 .
obo:PHIPO_0000832 a rdfs:Class ;
rdfs:label "sensitive to copper sulphate"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to copper sulphate. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_61296 a rdfs:Class ;
rdfs:label "adenyl ribonucleotide" ;
rdfs:comment "A purine riboncleotide where adenine is the purine." ;
rdfs:subClassOf obo:CHEBI_26400 , obo:CHEBI_61293 .
obo:GO_0070201 a rdfs:Class ;
rdfs:label "regulation of establishment of protein localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_0038023 a rdfs:Class ;
rdfs:label "signaling receptor activity" ;
rdfs:comment "Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response." ;
rdfs:subClassOf obo:GO_0060089 .
obo:GO_0140013 a rdfs:Class ;
rdfs:label "meiotic nuclear division" ;
rdfs:comment "One of the two nuclear divisions that occur as part of the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0000280 , obo:GO_1903046 .
obo:PHIPO_0001018 a rdfs:Class ;
rdfs:label "abnormal asexual spore germination"@en ;
rdfs:comment "A cellular process phenotype in which asexual spore germination is abnormal (GO:0009847)." ;
rdfs:subClassOf obo:PHIPO_0000930 .
obo:GO_1901163 a rdfs:Class ;
rdfs:label "regulation of trophoblast cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of trophoblast cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:PHIPO_0000889 a rdfs:Class ;
rdfs:label "sensitive to clindamycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to clindamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0003061 a rdfs:Class ;
rdfs:label "blood island" ;
rdfs:comment "Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_1903564 a rdfs:Class ;
rdfs:label "regulation of protein localization to cilium" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to cilium." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:UBERON_0002167 a rdfs:Class ;
rdfs:label "right lung" ;
rdfs:comment "Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]." ;
rdfs:subClassOf obo:UBERON_0002048 .
obo:PATO_0000085 a rdfs:Class ;
rdfs:label "sensitivity toward" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's disposition to detect or perceive external stimulation." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:GO_0015669 a rdfs:Class ;
rdfs:label "gas transport" ;
rdfs:comment "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 .
obo:PHIPO_0000888 a rdfs:Class ;
rdfs:label "sensitive to tylosin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tylosin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_71543 a rdfs:Class ;
rdfs:label "rotenoid" ;
rdfs:comment "Members of the class of tetrahydrochromenochromene that consists of a cis-fused tetrahydrochromeno[3,4-b]chromene skeleton and its substituted derivatives. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds." ;
rdfs:subClassOf obo:CHEBI_72544 , obo:CHEBI_72579 .
obo:CHEBI_36047 a rdfs:Class ;
rdfs:label "antibacterial drug" ;
rdfs:comment "A drug used to treat or prevent bacterial infections." ;
rdfs:subClassOf obo:CHEBI_33282 , obo:CHEBI_36043 .
obo:GO_0003332 a rdfs:Class ;
rdfs:label "negative regulation of extracellular matrix constituent secretion" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells." ;
rdfs:subClassOf obo:GO_0003330 , obo:GO_0065007 , obo:GO_1903054 , obo:GO_1903531 .
obo:GO_0032332 a rdfs:Class ;
rdfs:label "positive regulation of chondrocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." ;
rdfs:subClassOf obo:GO_0032330 , obo:GO_0045597 , obo:GO_0061036 , obo:GO_0065007 .
obo:UBERON_0008814 a rdfs:Class ;
rdfs:label "pharyngeal arch system" ;
rdfs:comment "A transient embryonic complex that comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming, which may include (depending on species) the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear[GO,modified]." ;
rdfs:subClassOf obo:UBERON_0034921 .
a rdfs:Class ;
rdfs:label "Olfactory areas" ;
rdfs:subClassOf , obo:UBERON_0002894 .
obo:GO_0003205 a rdfs:Class ;
rdfs:label "cardiac chamber development" ;
rdfs:comment "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_59676 a rdfs:Class ;
rdfs:label "nystatins" ;
rdfs:comment "A class of polyene antifungal antibiotics produced by Streptomyces noursei, and other Streptomyces species." ;
rdfs:subClassOf obo:CHEBI_22507 , obo:CHEBI_25105 , obo:CHEBI_26191 , obo:CHEBI_36244 , obo:CHEBI_48121 , obo:CHEBI_87113 .
obo:GO_1905147 a rdfs:Class ;
rdfs:label "regulation of smooth muscle hypertrophy" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy." ;
rdfs:subClassOf obo:GO_0014743 , obo:GO_0043502 , obo:GO_0065007 .
obo:UBERON_0000061 a rdfs:Class ;
rdfs:label "anatomical structure" ;
rdfs:comment "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:UBERON_0005339 a rdfs:Class ;
rdfs:label "outflow tract pulmonary component" ;
rdfs:subClassOf obo:UBERON_0004145 .
obo:GO_0006082 a rdfs:Class ;
rdfs:label "organic acid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0044281 .
obo:GO_0098632 a rdfs:Class ;
rdfs:label "cell-cell adhesion mediator activity" ;
rdfs:comment "The binding by a cell-adhesion protein on the cell surface to an extracellular component of a different cell, to mediate adhesion of the cell to another cell." ;
rdfs:subClassOf obo:GO_0005515 , obo:GO_0098631 .
obo:CL_0000488 a rdfs:Class ;
rdfs:label "visible light photoreceptor cell" ;
rdfs:comment "A photoreceptor cell that detects visible light." ;
rdfs:subClassOf obo:CL_0000210 .
obo:UBERON_0035820 a rdfs:Class ;
rdfs:label "peritoneal sac" ;
rdfs:comment "A serous sac that is the aggregate of the peritoneum and the peritoneal cavity, located in the abdominal cavity." ;
rdfs:subClassOf obo:UBERON_0002075 , obo:UBERON_0005906 .
obo:CHEBI_58165 a rdfs:Class ;
rdfs:label "3',5'-cyclic AMP(1-)" ;
rdfs:comment "An organophosphate oxoanion that is the conjugate base of 3',5'-cyclic AMP arising from deprotonation of the free phosphate OH group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_58945 .
obo:CHEBI_478164 a rdfs:Class ;
rdfs:label "cefepime" ;
rdfs:comment "A cephalosporin bearing (1-methylpyrrolidinium-1-yl)methyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton." ;
rdfs:subClassOf obo:CHEBI_23066 , obo:CHEBI_26469 , obo:CHEBI_36816 .
obo:CHEBI_33675 a rdfs:Class ;
rdfs:label "p-block molecular entity" ;
rdfs:comment "A main group molecular entity that contains one or more atoms of a p-block element." ;
rdfs:subClassOf obo:CHEBI_33579 .
obo:GO_0014044 a rdfs:Class ;
rdfs:label "Schwann cell development" ;
rdfs:comment "The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function." ;
rdfs:subClassOf obo:GO_0021782 , obo:GO_0032502 .
obo:GO_0098992 a rdfs:Class ;
rdfs:label "neuronal dense core vesicle" ;
rdfs:comment "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals." ;
rdfs:subClassOf obo:GO_0031045 .
obo:CHEBI_35856 a rdfs:Class ;
rdfs:label "lipoxygenase inhibitor" ;
rdfs:comment "A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes." ;
rdfs:subClassOf obo:CHEBI_76837 .
obo:PATO_0001171 a rdfs:Class ;
rdfs:label "elastic" ;
rdfs:comment "An elasticity quality inhering in a bearer by virtue of the bearer's ability to recover its size and shape after deformation in any way." ;
rdfs:subClassOf obo:PATO_0001031 .
obo:PR_Q05117 a rdfs:Class ;
rdfs:label "tartrate-resistant acid phosphatase type 5 (mouse)" ;
rdfs:comment "A tartrate-resistant acid phosphatase type 5 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001937 , obo:PR_000029032 .
obo:UBERON_0007301 a rdfs:Class ;
rdfs:label "appendage blood vessel" ;
rdfs:comment "A blood vessel that is part of a limb/fin." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:CL_4300360 a rdfs:Class ;
rdfs:label "olfactory areas astrocyte (Mmus)" ;
rdfs:comment "A transcriptomically defined type of astrocyte located exclusively in the olfactory areas. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Hs3st3a1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:320 Astro-OLF NN." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000127 .
obo:GO_1903542 a rdfs:Class ;
rdfs:label "negative regulation of exosomal secretion" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion." ;
rdfs:subClassOf obo:GO_0045920 , obo:GO_0065007 , obo:GO_1903541 .
obo:CHEBI_135928 a rdfs:Class ;
rdfs:label "doripenem" ;
rdfs:subClassOf obo:CHEBI_46633 .
obo:PATO_0000608 a rdfs:Class ;
rdfs:label "closed" ;
rdfs:comment "A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view." ;
rdfs:subClassOf obo:PATO_0000136 .
obo:GO_0001701 a rdfs:Class ;
rdfs:label "in utero embryonic development" ;
rdfs:comment "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus." ;
rdfs:subClassOf obo:GO_0043009 .
obo:GO_0021915 a rdfs:Class ;
rdfs:label "neural tube development" ;
rdfs:comment "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium." ;
rdfs:subClassOf obo:GO_0035295 , obo:GO_0048856 , obo:GO_0060429 .
obo:CL_0010001 a rdfs:Class ;
rdfs:label "stromal cell of bone marrow" ;
rdfs:comment "A stromal cell that is part_of a bone marrow." ;
rdfs:subClassOf obo:CL_0000499 , obo:CL_0002092 .
obo:PHIPO_0000780 a rdfs:Class ;
rdfs:label "sensitive to epoxyconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to epoxyconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000265 a rdfs:Class ;
rdfs:label "abnormal protein transport"@en ;
rdfs:comment "A single organism cellular process phenotype in which protein transport is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000239 , obo:PHIPO_0000257 .
obo:PATO_0000461 a rdfs:Class ;
rdfs:label "normal" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." ;
rdfs:subClassOf obo:PATO_0000068 .
obo:UBERON_0003504 a rdfs:Class ;
rdfs:label "respiratory system blood vessel" ;
rdfs:comment "A blood vessel that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:GO_0014050 a rdfs:Class ;
rdfs:label "negative regulation of glutamate secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate." ;
rdfs:subClassOf obo:GO_0014048 , obo:GO_0032891 , obo:GO_0051956 , obo:GO_0065007 , obo:GO_1903531 .
obo:GO_0055024 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle tissue development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development." ;
rdfs:subClassOf obo:GO_0016202 , obo:GO_0065007 .
obo:PATO_0001564 a rdfs:Class ;
rdfs:label "extra or missing processual parts" ;
rdfs:comment "A quality of a process inhering in a bearer by virtue of the bearer's processual parts." ;
rdfs:subClassOf obo:PATO_0001236 .
obo:PHIPO_0001373 a rdfs:Class ;
rdfs:label "anatomical structure physical quality phenotype"@en ;
rdfs:comment "A phenotype that affects any anatomical structure physical quality, such as morphology, number, location, etc." ;
rdfs:subClassOf obo:PHIPO_0001220 .
obo:GO_0042445 a rdfs:Class ;
rdfs:label "hormone metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0010817 .
obo:PHIPO_0000531 a rdfs:Class ;
rdfs:label "resistance to cercosporamide"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cercosporamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0016301 a rdfs:Class ;
rdfs:label "kinase activity" ;
rdfs:comment "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ;
rdfs:subClassOf obo:GO_0003674 .
obo:GO_0099552 a rdfs:Class ;
rdfs:label "trans-synaptic signaling by lipid, modulating synaptic transmission" ;
rdfs:comment "Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse." ;
rdfs:subClassOf obo:GO_0099537 , obo:GO_0099541 , obo:GO_0099550 .
obo:UBERON_0002050 a rdfs:Class ;
rdfs:label "embryonic structure" ;
rdfs:comment "Anatomical structure that is part of an embryo." ;
rdfs:subClassOf obo:UBERON_0005423 .
obo:GO_0040034 a rdfs:Class ;
rdfs:label "regulation of development, heterochronic" ;
rdfs:comment "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." ;
rdfs:subClassOf obo:GO_0050793 .
obo:GO_1904178 a rdfs:Class ;
rdfs:label "negative regulation of adipose tissue development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1904177 .
obo:PHIPO_0000713 a rdfs:Class ;
rdfs:label "sensitive to mupirocin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to mupirocin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1904811 a rdfs:Class ;
rdfs:label "positive regulation of dense core granule transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dense core granule transport." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0065007 , obo:GO_1904809 .
obo:PHIPO_0000570 a rdfs:Class ;
rdfs:label "resistance to sulfanilamide"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to sulfanilamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_23357 a rdfs:Class ;
rdfs:label "cofactor" ;
rdfs:comment "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." ;
rdfs:subClassOf obo:CHEBI_52206 .
obo:GO_0046014 a rdfs:Class ;
rdfs:label "negative regulation of T cell homeostatic proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation." ;
rdfs:subClassOf obo:GO_0042130 , obo:GO_0046013 , obo:GO_0065007 .
obo:PATO_0002002 a rdfs:Class ;
rdfs:label "has extra parts of type" ;
rdfs:comment "The bearer of this quality has_part > n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part." ;
rdfs:subClassOf obo:PATO_0000470 , obo:PATO_0002083 , obo:PATO_0002305 .
obo:GO_0003213 a rdfs:Class ;
rdfs:label "cardiac right atrium morphogenesis" ;
rdfs:comment "The process in which the right cardiac atrium is generated and organized." ;
rdfs:subClassOf obo:GO_0003209 , obo:GO_0009653 .
obo:UBERON_0003933 a rdfs:Class ;
rdfs:label "cranial cartilage" ;
rdfs:comment "A cartilage element that is part of the cranial skeleton." ;
rdfs:subClassOf obo:UBERON_0007844 .
obo:CL_0000057 a rdfs:Class ;
rdfs:label "fibroblast" ;
rdfs:comment "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." ;
rdfs:subClassOf obo:CL_0000499 .
obo:CHEBI_26523 a rdfs:Class ;
rdfs:label "reactive oxygen species" ;
rdfs:comment "Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." ;
rdfs:subClassOf obo:CHEBI_25806 .
obo:PHIPO_0000420 a rdfs:Class ;
rdfs:label "normal pathogen chitin fragment binding"@en ;
rdfs:comment "A single species molecular function phenotype in which occurrence of pathogen chitin fragment binding by a pathogen gene product is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000418 .
obo:GO_0009309 a rdfs:Class ;
rdfs:label "amine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0009308 .
a rdfs:Class ;
rdfs:label "Pons, behavioral state related" ;
rdfs:subClassOf obo:BFO_0000004 .
obo:CHEBI_24675 a rdfs:Class ;
rdfs:label "hydroxybenzoate" ;
rdfs:comment "Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent." ;
rdfs:subClassOf obo:CHEBI_22718 , obo:CHEBI_36059 .
obo:GO_0045730 a rdfs:Class ;
rdfs:label "respiratory burst" ;
rdfs:comment "A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0008152 .
obo:UBERON_0003343 a rdfs:Class ;
rdfs:label "mucosa of oral region" ;
rdfs:comment "A mucosa that is part of a oral opening [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0003729 .
obo:CHEBI_28976 a rdfs:Class ;
rdfs:label "carbonic acid" ;
rdfs:subClassOf obo:CHEBI_35605 , obo:CHEBI_36961 .
obo:GO_0003357 a rdfs:Class ;
rdfs:label "noradrenergic neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030182 .
obo:GO_0150106 a rdfs:Class ;
rdfs:label "regulation of protein localization to cell-cell junction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:CHEBI_25807 a rdfs:Class ;
rdfs:label "organooxygen heterocyclic antibiotic" ;
rdfs:subClassOf obo:CHEBI_24531 .
obo:PHIPO_0000012 a rdfs:Class ;
rdfs:label "unaffected virulence" ;
rdfs:comment "A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is unchanged (i.e. the same degree of infectious disease as wild-type interaction)." ;
rdfs:subClassOf obo:PHIPO_0000011 .
obo:GO_0006936 a rdfs:Class ;
rdfs:label "muscle contraction" ;
rdfs:comment "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." ;
rdfs:subClassOf obo:GO_0003012 .
obo:PR_O35305 a rdfs:Class ;
rdfs:label "tumor necrosis factor receptor superfamily member 11A (mouse)" ;
rdfs:comment "A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001954 , obo:PR_000029032 .
obo:PATO_0001999 a rdfs:Class ;
rdfs:label "lacks parts or has fewer parts of type" ;
rdfs:comment "The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type." ;
rdfs:subClassOf obo:PATO_0002083 .
obo:CHEBI_26421 a rdfs:Class ;
rdfs:label "pyridines" ;
rdfs:comment "Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:PHIPO_0001110 a rdfs:Class ;
rdfs:label "obsolete pathogen-induced decrease in host pH" ;
rdfs:comment "A pathogen host interaction phenotype where the pathogen induces a pH decrease within the host cell or cellular component." .
obo:GO_0021751 a rdfs:Class ;
rdfs:label "salivary nucleus development" ;
rdfs:comment "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048857 .
obo:CHEBI_61355 a rdfs:Class ;
rdfs:label "3-hydroxy carboxylic acid" ;
rdfs:comment "Any hydroxy carboxylic acid which contains a hydroxy group located β- to the carboxylic acid group." ;
rdfs:subClassOf obo:CHEBI_24669 .
obo:GO_0002053 a rdfs:Class ;
rdfs:label "positive regulation of mesenchymal cell proliferation" ;
rdfs:comment "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0010464 , obo:GO_0065007 .
obo:PR_Q64314 a rdfs:Class ;
rdfs:label "hematopoietic progenitor cell antigen CD34 (mouse)" ;
rdfs:comment "A CD34 molecule that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001003 , obo:PR_000029032 .
obo:GO_0060931 a rdfs:Class ;
rdfs:label "sinoatrial node cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." ;
rdfs:subClassOf obo:GO_0048468 , obo:GO_0060926 .
obo:GO_0019222 a rdfs:Class ;
rdfs:label "regulation of metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:CL_0000388 a rdfs:Class ;
rdfs:label "tendon cell" ;
rdfs:comment "An elongated fibroblast that is part of a tendon. Its cytoplasm is stretched between the collagen fibres of the tendon, and it possesses a central nucleus with a prominent nucleolus. Tendon cell has a well-developed rough endoplasmic reticulum, and it is responsible for the synthesis and turnover of tendon fibres and ground substance." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_1000307 .
obo:GO_0021683 a rdfs:Class ;
rdfs:label "cerebellar granular layer morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PHIPO_0000850 a rdfs:Class ;
rdfs:label "sensitive to 4-aminosalicylic acid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to 4-aminosalicylic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0032386 a rdfs:Class ;
rdfs:label "regulation of intracellular transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0060341 , obo:GO_0065007 .
obo:CL_0000027 a rdfs:Class ;
rdfs:label "smooth muscle cell neural crest derived" ;
rdfs:comment "A smooth muscle cell derived from the neural crest." ;
rdfs:subClassOf obo:CL_0000192 .
obo:GO_0009581 a rdfs:Class ;
rdfs:label "detection of external stimulus" ;
rdfs:comment "The series of events in which an external stimulus is received by a cell and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0009605 , obo:GO_0051606 .
obo:GO_0042074 a rdfs:Class ;
rdfs:label "cell migration involved in gastrulation" ;
rdfs:comment "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." ;
rdfs:subClassOf obo:GO_0001667 , obo:GO_0016477 .
obo:GO_0007346 a rdfs:Class ;
rdfs:label "regulation of mitotic cell cycle" ;
rdfs:comment "Any process that modulates the rate or extent of progress through the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0051726 , obo:GO_0065007 .
obo:GO_0031349 a rdfs:Class ;
rdfs:label "positive regulation of defense response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a defense response." ;
rdfs:subClassOf obo:GO_0031347 , obo:GO_0048584 , obo:GO_0065007 .
obo:PHIPO_0000095 a rdfs:Class ;
rdfs:label "obsolete abnormal mitosis in asexual reproduction" .
obo:GO_0023052 a rdfs:Class ;
rdfs:label "signaling" ;
rdfs:comment "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." ;
rdfs:subClassOf obo:GO_0050789 .
obo:CL_1001611 a rdfs:Class ;
rdfs:label "cerebellar neuron" ;
rdfs:comment "Neuron of the cerebellum." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000029 .
obo:CL_0000210 a rdfs:Class ;
rdfs:label "photoreceptor cell" ;
rdfs:comment "A cell specialized in detecting light stimuli that are involved in visual perception." ;
rdfs:subClassOf obo:CL_0000101 , obo:CL_0000540 , obo:CL_0008028 .
obo:CHEBI_23924 a rdfs:Class ;
rdfs:label "enzyme inhibitor" ;
rdfs:comment "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." ;
rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 .
obo:GO_0035272 a rdfs:Class ;
rdfs:label "exocrine system development" ;
rdfs:comment "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:CHEBI_35295 a rdfs:Class ;
rdfs:label "homopolycyclic compound" ;
rdfs:subClassOf obo:CHEBI_33597 , obo:CHEBI_33635 .
obo:UBERON_0035763 a rdfs:Class ;
rdfs:label "cavity of cardiac chamber" ;
rdfs:subClassOf obo:UBERON_0002553 .
obo:CL_2000028 a rdfs:Class ;
rdfs:label "cerebellum glutamatergic neuron" ;
rdfs:comment "Any glutamatergic neuron that is part of a cerebellum." ;
rdfs:subClassOf obo:CL_0000679 , obo:CL_1001611 .
obo:GO_0021564 a rdfs:Class ;
rdfs:label "vagus nerve development" ;
rdfs:comment "The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." ;
rdfs:subClassOf obo:GO_0021545 , obo:GO_0048856 .
obo:GO_0007407 a rdfs:Class ;
rdfs:label "neuroblast activation" ;
rdfs:comment "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." ;
rdfs:subClassOf obo:GO_0001775 .
obo:UBERON_0009854 a rdfs:Class ;
rdfs:label "digestive tract diverticulum" ;
rdfs:comment "Branch or outpocketing of the digestive tract." ;
rdfs:subClassOf obo:UBERON_0004921 , obo:UBERON_0009856 .
obo:GO_0048853 a rdfs:Class ;
rdfs:label "forebrain morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PATO_0002305 a rdfs:Class ;
rdfs:label "increased object quality" ;
rdfs:comment "A quality of an object that has a value that is increased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0001241 , obo:PATO_0002300 .
obo:CHEBI_47779 a rdfs:Class ;
rdfs:label "aminoglycoside" ;
rdfs:subClassOf obo:CHEBI_24400 .
obo:PHIPO_0001439 a rdfs:Class ;
rdfs:label "increased number of septa in asexual spore"@en ;
rdfs:comment "A single species phenotype where the frequency of occurrence of septum within an asexual spore is increased." ;
rdfs:subClassOf obo:PHIPO_0000127 .
obo:CHEBI_35573 a rdfs:Class ;
rdfs:label "organic mancude parent" ;
rdfs:subClassOf obo:CHEBI_33245 , obo:CHEBI_35568 .
obo:CHEBI_23003 a rdfs:Class ;
rdfs:label "carbamate ester" ;
rdfs:comment "Any ester of carbamic acid or its N-substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_33308 .
obo:PATO_0000912 a rdfs:Class ;
rdfs:label "increased rate" ;
rdfs:comment "A rate which is relatively high." ;
rdfs:subClassOf obo:PATO_0000161 , obo:PATO_0002304 .
obo:GO_0031338 a rdfs:Class ;
rdfs:label "regulation of vesicle fusion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vesicle fusion." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0060627 , obo:GO_0065007 .
obo:GO_0060038 a rdfs:Class ;
rdfs:label "cardiac muscle cell proliferation" ;
rdfs:comment "The expansion of a cardiac muscle cell population by cell division." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0014855 .
obo:PHIPO_0001201 a rdfs:Class ;
rdfs:label "obsolete pathogen effector phenotype" ;
rdfs:comment "A phenotype that is relevant to pathogen effectors." .
obo:GO_0023051 a rdfs:Class ;
rdfs:label "regulation of signaling" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a signaling process." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:CL_0008035 a rdfs:Class ;
rdfs:label "microcirculation associated smooth muscle cell"@en ;
rdfs:comment "Any vascular associated smooth muscle cell that is part of some microcirculatory vessel." ;
rdfs:subClassOf obo:CL_0000359 , obo:CL_0008034 .
obo:GO_0060456 a rdfs:Class ;
rdfs:label "positive regulation of digestive system process" ;
rdfs:comment "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0044058 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0008089 a rdfs:Class ;
rdfs:label "anterograde axonal transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0098930 .
obo:UBERON_0000467 a rdfs:Class ;
rdfs:label "anatomical system" ;
rdfs:comment "Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0032060 a rdfs:Class ;
rdfs:label "bleb assembly" ;
rdfs:comment "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0120031 .
obo:UBERON_0000415 a rdfs:Class ;
rdfs:label "artery wall" ;
rdfs:comment "An anatomical wall that is part of an artery [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0035965 .
obo:CHEBI_52217 a rdfs:Class ;
rdfs:label "pharmaceutical" ;
rdfs:comment "Any substance introduced into a living organism with therapeutic or diagnostic purpose." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:UBERON_0009537 a rdfs:Class ;
rdfs:label "vascular element of right lung" ;
rdfs:comment "A vascular plexus that is part of a right lung." ;
rdfs:subClassOf obo:UBERON_0000102 , obo:UBERON_0005629 .
obo:PHIPO_0000729 a rdfs:Class ;
rdfs:label "sensitive to miltefosine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to miltefosine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000505 a rdfs:Class ;
rdfs:label "phenotype"@en ;
rdfs:comment "Any of the set of observable characteristics of an organism resulting from the interaction of its genotype with the environment." .
obo:PHIPO_0000065 a rdfs:Class ;
rdfs:label "asexual spores increased in size"@en ;
rdfs:comment "A reproductive morphology phenotype where the size of the asexual spore is increased." ;
rdfs:subClassOf obo:PHIPO_0000081 .
obo:CHEBI_35281 a rdfs:Class ;
rdfs:label "onium betaine" ;
rdfs:comment "Neutral molecules having charge-separated forms with an onium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom." ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:CHEBI_23853 a rdfs:Class ;
rdfs:label "dithiol" ;
rdfs:subClassOf obo:CHEBI_29256 .
obo:CHEBI_23905 a rdfs:Class ;
rdfs:label "monoatomic anion" ;
rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_24867 .
obo:CL_0000438 a rdfs:Class ;
rdfs:label "luteinizing hormone secreting cell" ;
rdfs:comment "A peptide hormone secreting cell pituitary that produces luteinizing hormone." ;
rdfs:subClassOf obo:CL_0000151 .
obo:CHEBI_76507 a rdfs:Class ;
rdfs:label "marine metabolite" ;
rdfs:comment "Any metabolite produced during a metabolic reaction in marine macro- and microorganisms." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:GO_0098877 a rdfs:Class ;
rdfs:label "neurotransmitter receptor transport to plasma membrane" ;
rdfs:comment "The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles." ;
rdfs:subClassOf obo:GO_0015031 , obo:GO_0090150 , obo:GO_0098876 , obo:GO_0099637 , obo:GO_1990778 .
obo:GO_0051148 a rdfs:Class ;
rdfs:label "negative regulation of muscle cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0051147 , obo:GO_0065007 .
obo:CHEBI_10642 a rdfs:Class ;
rdfs:label "scyllo-inositol" ;
rdfs:subClassOf obo:CHEBI_23480 , obo:CHEBI_24848 .
obo:CHEBI_51356 a rdfs:Class ;
rdfs:label "penicillinate anion" ;
rdfs:comment "Any anion formed by loss of a proton from the carboxy group of a penicillin." ;
rdfs:subClassOf obo:CHEBI_47811 .
obo:GO_2000834 a rdfs:Class ;
rdfs:label "regulation of androgen secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of androgen secretion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000831 .
obo:GO_0034351 a rdfs:Class ;
rdfs:label "negative regulation of glial cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process." ;
rdfs:subClassOf obo:GO_0034350 , obo:GO_0043066 , obo:GO_0065007 .
obo:UBERON_0001905 a rdfs:Class ;
rdfs:label "pineal body" ;
rdfs:comment "A midline, cone like structure located in the dorso-caudal roof of the 3rd ventricle, attached by peduncles to the habenular and posterior commissures. The stalk contains nerve fibers, blood vessels, connective tissue and parenchymal cells (Paxinos, The Rat Central Nervous System, 2nd ed, pg 399)." ;
rdfs:subClassOf obo:UBERON_0003296 , obo:UBERON_0010134 .
obo:PHIPO_0001406 a rdfs:Class ;
rdfs:label "sensitive to dimethomorph" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to dimethomorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_64951 a rdfs:Class ;
rdfs:label "anti-HBV agent" ;
rdfs:comment "An antiviral agent that destroys or inhibits the replication of the hepatitis B virus." ;
rdfs:subClassOf obo:CHEBI_22587 .
obo:PHIPO_0001297 a rdfs:Class ;
rdfs:label "sensitive to arborcandin C"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to arborcandin C. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0010464 a rdfs:Class ;
rdfs:label "regulation of mesenchymal cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:PATO_0000161 a rdfs:Class ;
rdfs:label "rate" ;
rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time." ;
rdfs:subClassOf obo:PATO_0002062 .
a rdfs:Class ;
rdfs:subClassOf obo:UBERON_0001062 .
obo:GO_0070925 a rdfs:Class ;
rdfs:label "organelle assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0022607 .
obo:GO_0060271 a rdfs:Class ;
rdfs:label "cilium assembly" ;
rdfs:comment "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0044782 , obo:GO_0070925 , obo:GO_0120031 .
obo:GO_1900367 a rdfs:Class ;
rdfs:label "positive regulation of defense response to insect" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of defense response to insect." ;
rdfs:subClassOf obo:GO_0002833 , obo:GO_0031349 , obo:GO_0032103 , obo:GO_0065007 , obo:GO_2000068 .
obo:PHIPO_0000987 a rdfs:Class ;
rdfs:label "obsolete altered level of substance phenotype in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of a specific substance measured in a cell within a pathogen host interaction differs from normal." .
obo:PR_000001108 a rdfs:Class ;
rdfs:label "D(2)-like dopamine receptor" ;
rdfs:comment "A dopamine receptor that is a product of the DRD2, DRD3, or DRD4 gene. The active form binds dopamine and its activity is mediated by G proteins that cause inhibition of adenylate cyclase." ;
rdfs:subClassOf obo:PR_000044633 .
obo:GO_0003260 a rdfs:Class ;
rdfs:label "cardioblast migration" ;
rdfs:comment "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0060974 .
obo:GO_0110022 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle myoblast proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000291 .
obo:CHEBI_33286 a rdfs:Class ;
rdfs:label "agrochemical" ;
rdfs:comment "An agrochemical is a substance that is used in agriculture or horticulture." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_0050727 a rdfs:Class ;
rdfs:label "regulation of inflammatory response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents." ;
rdfs:subClassOf obo:GO_0031347 , obo:GO_0032101 , obo:GO_0065007 .
obo:PATO_0001393 a rdfs:Class ;
rdfs:label "euploid" ;
rdfs:comment "A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes." ;
rdfs:subClassOf obo:PATO_0001374 .
obo:UBERON_0005989 a rdfs:Class ;
rdfs:label "atrioventricular septum" ;
rdfs:comment "The wall of the heart that separates the right atrium and left ventricle; and is located just above the septal cusp of the tricuspid valve." ;
rdfs:subClassOf obo:UBERON_0002099 , obo:UBERON_0010313 .
obo:GO_1905504 a rdfs:Class ;
rdfs:label "negative regulation of motile cilium assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902018 , obo:GO_1905503 .
obo:PHIPO_0000110 a rdfs:Class ;
rdfs:label "abolished formation of pathogen penetration structure"@en ;
rdfs:comment "A single species pathogen growth phenotype in which the ability of the pathogen to form a specialized penetration structure is abolished when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000032 .
obo:GO_0032231 a rdfs:Class ;
rdfs:label "regulation of actin filament bundle assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." ;
rdfs:subClassOf obo:GO_0044087 , obo:GO_0065007 , obo:GO_0110053 .
obo:CL_4307113 a rdfs:Class ;
rdfs:label "ABC NN_1 Pde11a arachnoid barrier cell (Mmus)" ;
rdfs:comment "A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc47a1 (Mmus), Pde11a (Mmus). It is distinguished from other ABC NN cells by expression of Pde11a. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5293 ABC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301616 .
obo:PHIPO_0000669 a rdfs:Class ;
rdfs:label "resistance to fenarimol"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fenarimol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_35223 a rdfs:Class ;
rdfs:label "catalyst" ;
rdfs:comment "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:PHIPO_0000125 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen growth post penetration present" .
obo:PHIPO_0001189 a rdfs:Class ;
rdfs:label "obsolete compatible interaction" ;
rdfs:comment "A pathogen host interaction phenotype where the gene-for-gene relationship between the pathogen and plant host results in disease susceptibility." .
obo:UBERON_0013522 a rdfs:Class ;
rdfs:label "subdivision of tube" ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:GO_1904141 a rdfs:Class ;
rdfs:label "positive regulation of microglial cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of microglial cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903977 , obo:GO_1904139 , obo:GO_1905523 .
obo:CHEBI_25106 a rdfs:Class ;
rdfs:label "macrolide" ;
rdfs:comment "A macrocyclic lactone with a ring of twelve or more members derived from a polyketide." ;
rdfs:subClassOf obo:CHEBI_26188 , obo:CHEBI_63944 .
obo:GO_1901890 a rdfs:Class ;
rdfs:label "positive regulation of cell junction assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell junction assembly." ;
rdfs:subClassOf obo:GO_0044089 , obo:GO_0051130 , obo:GO_0065007 , obo:GO_1901888 .
obo:UBERON_0035804 a rdfs:Class ;
rdfs:label "future mouth" ;
rdfs:comment "The primordial mouth region of the developing head." ;
rdfs:subClassOf obo:UBERON_0013522 .
obo:PHIPO_0000319 a rdfs:Class ;
rdfs:label "obsolete decreased effector of virulence suppression of host defense" ;
rdfs:comment "The pathogen effector entity has a decreased ability to suppress host defense." .
obo:CHEBI_58955 a rdfs:Class ;
rdfs:label "branched-chain fatty acid anion" ;
rdfs:comment "Any fatty acid anion with a carbon side-chain or isopropyl termination." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:PHIPO_0000283 a rdfs:Class ;
rdfs:label "obsolete normal stature" .
obo:GO_0005856 a rdfs:Class ;
rdfs:label "cytoskeleton" ;
rdfs:comment "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." ;
rdfs:subClassOf obo:GO_0043232 .
obo:GO_0021559 a rdfs:Class ;
rdfs:label "trigeminal nerve development" ;
rdfs:comment "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." ;
rdfs:subClassOf obo:GO_0021545 , obo:GO_0048856 .
obo:UBERON_0003684 a rdfs:Class ;
rdfs:label "abdominal cavity" ;
rdfs:comment "The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity)." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:UBERON_0004142 a rdfs:Class ;
rdfs:label "outflow tract septum" ;
rdfs:comment "The outflow tract septum is a partition in the outflow tract." ;
rdfs:subClassOf obo:UBERON_0002099 .
obo:GO_0009712 a rdfs:Class ;
rdfs:label "catechol-containing compound metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0018958 .
obo:GO_0005677 a rdfs:Class ;
rdfs:label "chromatin silencing complex" ;
rdfs:comment "Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0140513 .
obo:CHEBI_76857 a rdfs:Class ;
rdfs:label "EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor" ;
rdfs:comment "An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD+ or NADP+ as acceptor (EC 1.3.1.*)." ;
rdfs:subClassOf obo:CHEBI_76729 .
obo:GO_0170036 a rdfs:Class ;
rdfs:label "import into the mitochondrion" ;
rdfs:comment "The directed movement of substances from the cytosol into the mitochondrion." ;
rdfs:subClassOf obo:GO_0010496 , obo:GO_0046907 , obo:GO_1990542 .
obo:GO_1902463 a rdfs:Class ;
rdfs:label "protein localization to cell leading edge" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a cell leading edge." ;
rdfs:subClassOf obo:GO_0008104 .
obo:UBERON_0003350 a rdfs:Class ;
rdfs:label "epithelium of mucosa" ;
rdfs:comment "A layer of epithelial cells on the surface of the mucosa." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0014734 a rdfs:Class ;
rdfs:label "skeletal muscle hypertrophy" ;
rdfs:comment "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." ;
rdfs:subClassOf obo:GO_0014896 , obo:GO_0014897 , obo:GO_0043501 .
obo:UBERON_0004571 a rdfs:Class ;
rdfs:label "systemic arterial system" ;
rdfs:comment "The part of the arterial system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart." ;
rdfs:subClassOf obo:UBERON_0007798 .
obo:GO_0060956 a rdfs:Class ;
rdfs:label "endocardial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." ;
rdfs:subClassOf obo:GO_0003348 , obo:GO_0030154 .
obo:PATO_0045000 a rdfs:Class ;
rdfs:label "normal rate" ;
rdfs:comment "A rate which is relatively normal." ;
rdfs:subClassOf obo:PATO_0000161 , obo:PATO_0045073 .
obo:CHEBI_18133 a rdfs:Class ;
rdfs:label "hexose" ;
rdfs:comment "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." ;
rdfs:subClassOf obo:CHEBI_35381 .
obo:GO_0034491 a rdfs:Class ;
rdfs:label "neutral amino acid transmembrane import into vacuole" ;
rdfs:comment "The directed movement of neutral amino acids into the vacuole across the vacuolar membrane." ;
rdfs:subClassOf obo:GO_0015804 , obo:GO_0032975 .
obo:CHEBI_24835 a rdfs:Class ;
rdfs:label "inorganic molecular entity" ;
rdfs:comment "A molecular entity that contains no carbon." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:GO_0045766 a rdfs:Class ;
rdfs:label "positive regulation of angiogenesis" ;
rdfs:comment "Any process that activates or increases angiogenesis." ;
rdfs:subClassOf obo:GO_0045765 , obo:GO_0065007 , obo:GO_1904018 .
obo:CHEBI_28965 a rdfs:Class ;
rdfs:label "dicarboxylic acid dianion" ;
rdfs:comment "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." ;
rdfs:subClassOf obo:CHEBI_35693 , obo:CHEBI_38716 .
obo:UBERON_0001710 a rdfs:Class ;
rdfs:label "lower jaw region" ;
rdfs:comment "Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]." ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:CHEBI_50910 a rdfs:Class ;
rdfs:label "neurotoxin" ;
rdfs:comment "A poison that interferes with the functions of the nervous system." ;
rdfs:subClassOf obo:CHEBI_52209 , obo:CHEBI_64909 .
obo:PHIPO_0001190 a rdfs:Class ;
rdfs:label "obsolete incompatible interaction" ;
rdfs:comment "A pathogen host interaction phenotype where the gene-for-gene relationship between the pathogen and plant host results in disease resistance." .
obo:GO_1905627 a rdfs:Class ;
rdfs:label "regulation of serotonin biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0065007 .
obo:PR_000001753 a rdfs:Class ;
rdfs:label "transcription factor NF-kappa-B subunit" ;
rdfs:comment "A protein that has a core domain composition consisting of a Rel homology domain (RHD) (Pfam:PF00554), an IPT/TIG domain (Pfam:PF01833), six copies of the Ankyrin repeat (Pfam:PF00023), a Death domain (Pfam:PF00531) and a C-terminal PEST region." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0031445 a rdfs:Class ;
rdfs:label "regulation of heterochromatin formation" ;
rdfs:comment "Any process that modulates the frequency, rate, extent or location of heterochromatin formation." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0065007 , obo:GO_0120261 .
obo:GO_0045683 a rdfs:Class ;
rdfs:label "negative regulation of epidermis development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development." ;
rdfs:subClassOf obo:GO_0045682 , obo:GO_0051093 , obo:GO_0065007 .
obo:UBERON_0035549 a rdfs:Class ;
rdfs:label "vasculature of integument" ;
rdfs:comment "The part of the circulatory system that lies within the subcutaneous tissue layers close to the surface of the skin." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:GO_0030334 a rdfs:Class ;
rdfs:label "regulation of cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000145 .
obo:UBERON_0004582 a rdfs:Class ;
rdfs:label "venous system" ;
rdfs:comment "The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions." ;
rdfs:subClassOf obo:UBERON_0007798 .
obo:GO_0010615 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle adaptation" ;
rdfs:comment "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." ;
rdfs:subClassOf obo:GO_0010612 , obo:GO_0014744 , obo:GO_0065007 .
obo:GO_0003433 a rdfs:Class ;
rdfs:label "chondrocyte development involved in endochondral bone morphogenesis" ;
rdfs:comment "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone." ;
rdfs:subClassOf obo:GO_0002063 .
obo:CL_1000307 a rdfs:Class ;
rdfs:label "fibroblast of dense regular elastic tissue" ;
rdfs:comment "A fibroblast that is part of the dense regular elastic tissue." ;
rdfs:subClassOf obo:CL_0000057 .
obo:UBERON_0001932 a rdfs:Class ;
rdfs:label "arcuate nucleus of hypothalamus" ;
rdfs:comment "The arcuate nucleus (or infundibular nucleus) is an aggregation of neurons in the mediobasal hypothalamus, adjacent to the third ventricle and the median eminence. The arcuate nucleus includes several important populations of neurons, including: Neuroendocrine neurons, Centrally-projecting neurons and Others. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0006568 .
obo:GO_0031012 a rdfs:Class ;
rdfs:label "extracellular matrix" ;
rdfs:comment "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." ;
rdfs:subClassOf obo:GO_0030312 .
obo:PHIPO_0000045 a rdfs:Class ;
rdfs:label "normal asexual reproduction"@en ;
rdfs:comment "A single species phenotype where the asexual reproduction process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is normal (indistinguishable from wild type)(GO:0019954)." ;
rdfs:subClassOf obo:PHIPO_0000044 .
obo:GO_0008594 a rdfs:Class ;
rdfs:label "photoreceptor cell morphogenesis" ;
rdfs:comment "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048667 .
obo:GO_0048873 a rdfs:Class ;
rdfs:label "homeostasis of number of cells within a tissue" ;
rdfs:comment "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue." ;
rdfs:subClassOf obo:GO_0001894 , obo:GO_0048872 .
obo:GO_0033238 a rdfs:Class ;
rdfs:label "regulation of amine metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_0051080 a rdfs:Class ;
rdfs:label "meiosis II nuclear membrane disassembly" ;
rdfs:comment "The controlled breakdown of the nuclear membranes during the second division of meiosis." ;
rdfs:subClassOf obo:GO_0051078 , obo:GO_0051081 .
obo:GO_0036334 a rdfs:Class ;
rdfs:label "epidermal stem cell homeostasis" ;
rdfs:comment "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells." ;
rdfs:subClassOf obo:GO_0048872 .
obo:GO_0045986 a rdfs:Class ;
rdfs:label "negative regulation of smooth muscle contraction" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction." ;
rdfs:subClassOf obo:GO_0006940 , obo:GO_0045932 , obo:GO_0065007 .
obo:UBERON_0004522 a rdfs:Class ;
rdfs:label "vasculature of musculoskeletal system" ;
rdfs:comment "A vasculature that is part of a musculoskeletal system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:CL_0000630 a rdfs:Class ;
rdfs:label "supporting cell" ;
rdfs:comment "A cell whose primary function is to support other cell types." ;
rdfs:subClassOf obo:CL_0000000 .
obo:CHEBI_33259 a rdfs:Class ;
rdfs:label "elemental molecular entity" ;
rdfs:comment "A molecular entity all atoms of which have the same atomic number." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:UBERON_0005178 a rdfs:Class ;
rdfs:label "thoracic cavity element" ;
rdfs:comment "An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0002075 , obo:UBERON_0005181 .
obo:CHEBI_37407 a rdfs:Class ;
rdfs:label "cyclic ether" ;
rdfs:comment "Any ether in which the oxygen atom forms part of a ring." ;
rdfs:subClassOf obo:CHEBI_25698 , obo:CHEBI_38104 .
obo:CHEBI_78298 a rdfs:Class ;
rdfs:label "environmental contaminant" ;
rdfs:comment "Any minor or unwanted substance introduced into the environment that can have undesired effects." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:CHEBI_70727 a rdfs:Class ;
rdfs:label "topoisomerase inhibitor" ;
rdfs:comment "An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA)." ;
rdfs:subClassOf obo:CHEBI_76830 .
obo:GO_0019882 a rdfs:Class ;
rdfs:label "antigen processing and presentation" ;
rdfs:comment "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." ;
rdfs:subClassOf obo:GO_0002376 .
obo:CL_4307063 a rdfs:Class ;
rdfs:label "Tanycyte NN_1 Cnmd tanycyte of subfornical organ (Mmus)" ;
rdfs:comment "A tanycyte of subfornical organ of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cnmd (Mmus), Sfta3-ps (Mmus). It is distinguished from other Tanycyte NN_1 cells by expression of Cnmd. These cells are located in the brain , in or close to the regions: choroid plexus, third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5243 Tanycyte NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0008042 , obo:CL_4301602 .
obo:GO_0002407 a rdfs:Class ;
rdfs:label "dendritic cell chemotaxis" ;
rdfs:comment "The movement of a dendritic cell in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0030595 , obo:GO_0036336 .
obo:CL_0000120 a rdfs:Class ;
rdfs:label "granule cell" ;
rdfs:comment "A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb." ;
rdfs:subClassOf obo:CL_2000029 .
obo:GO_1904677 a rdfs:Class ;
rdfs:label "positive regulation of somatic stem cell division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of somatic stem cell division." ;
rdfs:subClassOf obo:GO_0051781 , obo:GO_0065007 , obo:GO_1904675 .
obo:GO_0090304 a rdfs:Class ;
rdfs:label "nucleic acid metabolic process" ;
rdfs:comment "Any cellular metabolic process involving nucleic acids." ;
rdfs:subClassOf obo:GO_0006139 , obo:GO_0008152 , obo:GO_0043170 .
obo:GO_0007519 a rdfs:Class ;
rdfs:label "skeletal muscle tissue development" ;
rdfs:comment "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers." ;
rdfs:subClassOf obo:GO_0014706 , obo:GO_0048856 .
obo:GO_0051250 a rdfs:Class ;
rdfs:label "negative regulation of lymphocyte activation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation." ;
rdfs:subClassOf obo:GO_0002695 , obo:GO_0051249 , obo:GO_0065007 .
obo:UBERON_0014389 a rdfs:Class ;
rdfs:label "gustatory papilla of tongue" ;
rdfs:comment "A papilla that contain taste buds, including the fungiform, foliate, and circumvallate papillae." ;
rdfs:subClassOf obo:UBERON_0001726 .
obo:GO_1900924 a rdfs:Class ;
rdfs:label "negative regulation of glycine import across plasma membrane" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell." ;
rdfs:subClassOf obo:GO_0032891 , obo:GO_0034763 , obo:GO_0051956 , obo:GO_0065007 , obo:GO_1900923 .
obo:PR_000001850 a rdfs:Class ;
rdfs:label "cathepsin K" ;
rdfs:comment "A cathepsin-like protease that is a translation product of the human CTSK gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000040662 .
obo:CHEBI_171664 a rdfs:Class ;
rdfs:label "antiamoebic agent" ;
rdfs:comment "An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae." ;
rdfs:subClassOf obo:CHEBI_35442 .
obo:PHIPO_0000109 a rdfs:Class ;
rdfs:label "premature penetration structure formation"@en ;
rdfs:comment "A single species pathogen growth phenotype in which formation of pathogen specialized penetration structure begins sooner than normal when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000032 .
obo:UBERON_8000007 a rdfs:Class ;
rdfs:label "right side of back" ;
rdfs:comment "Right part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane." ;
rdfs:subClassOf obo:UBERON_0001137 , obo:UBERON_0015212 .
obo:GO_0110110 a rdfs:Class ;
rdfs:label "positive regulation of animal organ morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_2000027 .
obo:GO_0043169 a rdfs:Class ;
rdfs:label "cation binding" ;
rdfs:comment "Binding to a cation, a charged atom or group of atoms with a net positive charge." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0043167 .
obo:UBERON_0017672 a rdfs:Class ;
rdfs:label "abdominal viscera" ;
rdfs:comment "A viscus that is part of a abdomen." ;
rdfs:subClassOf obo:UBERON_0002075 , obo:UBERON_0005172 .
obo:GO_0060133 a rdfs:Class ;
rdfs:label "somatotropin secreting cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:UBERON_0001975 a rdfs:Class ;
rdfs:label "serosa of esophagus" ;
rdfs:comment "A serous membrane that is part of a esophagus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000042 .
obo:GO_0061983 a rdfs:Class ;
rdfs:label "meiosis II cell cycle process" ;
rdfs:comment "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes." ;
rdfs:subClassOf obo:GO_1903046 .
obo:UBERON_0003832 a rdfs:Class ;
rdfs:label "esophagus muscle" ;
rdfs:comment "Any muscle organ that is part of a esophagus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001630 , obo:UBERON_0013765 .
obo:UBERON_0004706 a rdfs:Class ;
rdfs:label "bulbus cordis" ;
rdfs:comment "A transient fetal dilation of the distal (or cranial) heart tube located where the arterial trunk joins the ventral roots of the aortic arches." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0150107 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to cell-cell junction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0150106 , obo:GO_1903829 .
obo:PHIPO_0000976 a rdfs:Class ;
rdfs:label "decreased lipid droplet degradation"@en ;
rdfs:comment "A single organism metabolic process phenotype in which the occurrence of lipid droplet degradation (lipolysis) is decreased (GO:0016042 and GO:0005811)." ;
rdfs:subClassOf obo:PHIPO_0000478 , obo:PHIPO_0000493 , obo:PHIPO_0000929 .
obo:GO_1903538 a rdfs:Class ;
rdfs:label "regulation of meiotic cell cycle process involved in oocyte maturation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0065007 , obo:GO_2000241 .
obo:PHIPO_0000415 a rdfs:Class ;
rdfs:label "abnormal subcellular component"@en ;
rdfs:comment "A single organism phenotype in which the amount, distribution, composition or morphology of a cell part is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000463 .
obo:GO_0001842 a rdfs:Class ;
rdfs:label "neural fold formation" ;
rdfs:comment "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove." ;
rdfs:subClassOf obo:GO_0016331 , obo:GO_0048646 , obo:GO_0060571 .
obo:UBERON_0004023 a rdfs:Class ;
rdfs:label "ganglionic eminence" ;
rdfs:comment "The transient proliferative population of neurons that expands exponentially during late prenatal development; it is a continuous germinal zone distinct from the ventricular zone that surrounds the brain ventricles[MP]." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:CHEBI_35718 a rdfs:Class ;
rdfs:label "antifungal agent" ;
rdfs:comment "An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce." ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:IDO_0000626 a rdfs:Class ;
rdfs:label "appearance of disorder"@en ;
rdfs:comment "A process by which a disorder comes into existence."@en ;
rdfs:subClassOf obo:GO_0008150 .
obo:CHEBI_3015 a rdfs:Class ;
rdfs:label "benomyl" ;
rdfs:comment "A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops." ;
rdfs:subClassOf obo:CHEBI_62733 , obo:CHEBI_87036 , obo:CHEBI_87064 .
obo:GO_0032973 a rdfs:Class ;
rdfs:label "amino acid export across plasma membrane" ;
rdfs:comment "The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region." ;
rdfs:subClassOf obo:GO_0003333 , obo:GO_0006810 , obo:GO_0140115 .
obo:GO_0032241 a rdfs:Class ;
rdfs:label "positive regulation of nucleobase-containing compound transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032239 , obo:GO_0051050 , obo:GO_0065007 .
obo:GO_1904588 a rdfs:Class ;
rdfs:label "cellular response to glycoprotein" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_1901701 , obo:GO_1904587 .
obo:GO_0005874 a rdfs:Class ;
rdfs:label "microtubule" ;
rdfs:comment "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." ;
rdfs:subClassOf obo:GO_0099513 .
obo:GO_1990502 a rdfs:Class ;
rdfs:label "dense core granule maturation" ;
rdfs:comment "Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0061792 .
obo:PHIPO_0000228 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host interaction biosynthesis of deoxynivalenol" ;
rdfs:comment "A pathogen host interaction phenotype in which the pathogen biosynthesis of deoxynivalenol is normal (i.e. same as the wild type)." .
obo:GO_0051650 a rdfs:Class ;
rdfs:label "establishment of vesicle localization" ;
rdfs:comment "The directed movement of a vesicle to a specific location." ;
rdfs:subClassOf obo:GO_0051234 , obo:GO_0051648 , obo:GO_0051649 , obo:GO_0051656 .
obo:UBERON_0003324 a rdfs:Class ;
rdfs:label "mesenchyme of lower jaw" ;
rdfs:comment "Mesenchyme that is part of a developing lower jaw [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0034995 .
obo:UBERON_0012320 a rdfs:Class ;
rdfs:label "cervical artery" ;
rdfs:comment "An artery of the neck." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0003502 .
obo:GO_1902475 a rdfs:Class ;
rdfs:label "L-alpha-amino acid transmembrane transport" ;
rdfs:comment "The directed movement of L-alpha-amino acid across a membrane by means of some agent such as a transporter or a pore." ;
rdfs:subClassOf obo:GO_0003333 , obo:GO_0015807 , obo:GO_0055085 , obo:GO_1905039 .
obo:UBERON_0003462 a rdfs:Class ;
rdfs:label "facial bone" ;
rdfs:comment "A bone that is part of a facial skeleton [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0003457 .
obo:GO_1901652 a rdfs:Class ;
rdfs:label "response to peptide" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." ;
rdfs:subClassOf obo:GO_0042221 , obo:GO_0050896 .
obo:CHEBI_33567 a rdfs:Class .
obo:GO_0030224 a rdfs:Class ;
rdfs:label "monocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte." ;
rdfs:subClassOf obo:GO_0002573 , obo:GO_0030154 , obo:GO_1903131 .
obo:GO_0014896 a rdfs:Class ;
rdfs:label "muscle hypertrophy" ;
rdfs:comment "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy." ;
rdfs:subClassOf obo:GO_0003012 .
obo:GO_1903978 a rdfs:Class ;
rdfs:label "regulation of microglial cell activation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of microglial cell activation." ;
rdfs:subClassOf obo:GO_0043030 , obo:GO_0065007 , obo:GO_0150077 .
obo:GO_0008652 a rdfs:Class ;
rdfs:label "amino acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." ;
rdfs:subClassOf obo:GO_0006520 , obo:GO_0009058 .
obo:GO_0001818 a rdfs:Class ;
rdfs:label "negative regulation of cytokine production" ;
rdfs:comment "Any process that stops, prevents, or reduces the rate of production of a cytokine." ;
rdfs:subClassOf obo:GO_0001817 , obo:GO_0010629 , obo:GO_0051241 , obo:GO_0065007 .
obo:CHEBI_22390 a rdfs:Class ;
rdfs:label "alpha-D-glucoside" ;
rdfs:subClassOf obo:CHEBI_35436 , obo:CHEBI_60979 .
obo:UBERON_0004455 a rdfs:Class ;
rdfs:label "neurula embryo" ;
rdfs:comment "An embryo at the neurula stage." ;
rdfs:subClassOf obo:UBERON_0000468 , obo:UBERON_0000922 .
obo:GO_0045670 a rdfs:Class ;
rdfs:label "regulation of osteoclast differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of osteoclast differentiation." ;
rdfs:subClassOf obo:GO_0002761 , obo:GO_0065007 .
obo:PHIPO_0001164 a rdfs:Class ;
rdfs:label "obsolete abnormal host reproductive structure development induced by pathogen" ;
rdfs:comment "A host reproductive phenotype with pathogen where the process of host reproductive development is abnormal (GO:0048608)." .
obo:GO_0001961 a rdfs:Class ;
rdfs:label "positive regulation of cytokine-mediated signaling pathway" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway." ;
rdfs:subClassOf obo:GO_0001959 , obo:GO_0009967 , obo:GO_0060760 , obo:GO_0065007 .
obo:CHEBI_26764 a rdfs:Class .
obo:PHIPO_0001450 a rdfs:Class ;
rdfs:label "resistance to sodium dodecyl sulfate"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to sodium dodecyl sulfate (SDS). Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001109 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen-induced host pH" ;
rdfs:comment "A pathogen host interaction phenotype, in which the host pH value during infection differs from normal." .
obo:GO_0051891 a rdfs:Class ;
rdfs:label "positive regulation of cardioblast differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ;
rdfs:subClassOf obo:GO_0051890 , obo:GO_0065007 , obo:GO_1905209 , obo:GO_2000738 .
obo:UBERON_0004064 a rdfs:Class ;
rdfs:label "neural tube basal plate" ;
rdfs:comment "The region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons." ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:PHIPO_0001313 a rdfs:Class ;
rdfs:label "resistance to zoxamide"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to zoxamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0035563 a rdfs:Class ;
rdfs:label "positive regulation of chromatin binding" ;
rdfs:comment "Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." ;
rdfs:subClassOf obo:GO_0051099 , obo:GO_0065007 .
obo:UBERON_0034929 a rdfs:Class ;
rdfs:label "external soft tissue zone" ;
rdfs:comment "A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures." ;
rdfs:subClassOf obo:UBERON_0010000 , obo:UBERON_0010314 .
obo:UBERON_0004492 a rdfs:Class ;
rdfs:label "cardiac muscle tissue of cardiac septum" ;
rdfs:comment "A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001133 .
obo:UBERON_0006516 a rdfs:Class ;
rdfs:label "dorsal pallidum" ;
rdfs:comment "The predominant portion of the globus pallidus in the striatopallidal system, which is defined by connectivity and neurochemical staining. The dorsal pallidum is distinguished from the ventral pallidum by a boundary that is partially defined by the anterior commissure. The remainder of the boundary is indistinct in sections stained for Nissl substance ( Heimer-1995 )." ;
rdfs:subClassOf obo:UBERON_0005401 , obo:UBERON_0006514 .
obo:GO_0048320 a rdfs:Class ;
rdfs:label "axial mesoderm formation" ;
rdfs:comment "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0001707 , obo:GO_0048646 .
obo:GO_0060461 a rdfs:Class ;
rdfs:label "right lung morphogenesis" ;
rdfs:comment "The process in which anatomical structures of the right lung are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060425 .
obo:CHEBI_46761 a rdfs:Class ;
rdfs:label "dipeptide" ;
rdfs:comment "Any molecule that contains two amino-acid residues connected by peptide linkages." ;
rdfs:subClassOf obo:CHEBI_25676 .
obo:CHEBI_51143 a rdfs:Class ;
rdfs:label "nitrogen molecular entity" ;
rdfs:subClassOf obo:CHEBI_33302 .
obo:CHEBI_83297 a rdfs:Class ;
rdfs:label "4-dodecyl-2,6-dimethylmorpholine" ;
rdfs:comment "A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a dodecyl group. The configuration at positions 2 and 6 is unknown or unspecified." ;
rdfs:subClassOf obo:CHEBI_38785 , obo:CHEBI_50996 .
obo:GO_0061299 a rdfs:Class ;
rdfs:label "retina vasculature morphogenesis in camera-type eye" ;
rdfs:comment "The process in which the vasculature of the retina is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0045672 a rdfs:Class ;
rdfs:label "positive regulation of osteoclast differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of osteoclast differentiation." ;
rdfs:subClassOf obo:GO_0002763 , obo:GO_0045670 , obo:GO_0065007 .
obo:PHIPO_0000991 a rdfs:Class ;
rdfs:label "increased level of host defense-induced protein"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host protein usually present during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001262 .
obo:CL_4307102 a rdfs:Class ;
rdfs:label "MFOL NN_3 Cxcl12 myelin-forming oligodendrocyte (Mmus)" ;
rdfs:comment "A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Opalin (Mmus), Cxcl12 (Mmus), Efhd1 (Mmus). It is distinguished from other MFOL NN_3 cells by expression of Cxcl12, Efhd1. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5282 MFOL NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301613 .
obo:UBERON_0018260 a rdfs:Class ;
rdfs:label "layer of muscle tissue" ;
rdfs:comment "Any organ component layer that consists of muscle tissue." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:UBERON_0003037 a rdfs:Class ;
rdfs:label "septum" ;
rdfs:comment "A wall, dividing a cavity or structure into smaller ones[WP]." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0046849 a rdfs:Class ;
rdfs:label "bone remodeling" ;
rdfs:comment "The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis." ;
rdfs:subClassOf obo:GO_0048771 .
obo:GO_1903561 a rdfs:Class ;
rdfs:label "extracellular vesicle" ;
rdfs:comment "Any vesicle that is part of the extracellular region." ;
rdfs:subClassOf obo:GO_0031982 , obo:GO_0065010 .
obo:GO_0150076 a rdfs:Class ;
rdfs:label "neuroinflammatory response" ;
rdfs:comment "The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents." ;
rdfs:subClassOf obo:GO_0006954 .
obo:CHEBI_22587 a rdfs:Class ;
rdfs:label "antiviral agent" ;
rdfs:comment "A substance that destroys or inhibits replication of viruses." ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:GO_0061303 a rdfs:Class ;
rdfs:label "cornea development in camera-type eye" ;
rdfs:comment "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0048485 a rdfs:Class ;
rdfs:label "sympathetic nervous system development" ;
rdfs:comment "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:CHEBI_3745 a rdfs:Class ;
rdfs:label "clindamycin" ;
rdfs:comment "A carbohydrate-containing antibiotic that is the semisynthetic derivative of lincomycin, a natural antibiotic." ;
rdfs:subClassOf obo:CHEBI_23007 , obo:CHEBI_35275 , obo:CHEBI_36683 , obo:CHEBI_46770 , obo:CHEBI_72588 .
obo:GO_0006325 a rdfs:Class ;
rdfs:label "chromatin organization" ;
rdfs:comment "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA." ;
rdfs:subClassOf obo:GO_0016043 .
obo:GO_2000174 a rdfs:Class ;
rdfs:label "regulation of pro-T cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of pro-T cell differentiation." ;
rdfs:subClassOf obo:GO_0045580 , obo:GO_0065007 , obo:GO_1905456 .
obo:CL_0000679 a rdfs:Class ;
rdfs:label "glutamatergic neuron" ;
rdfs:comment "A neuron that is capable of some neurotansmission by glutamate secretion." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000540 .
obo:UBERON_0000437 a rdfs:Class ;
rdfs:label "arachnoid barrier layer" ;
rdfs:comment "The arachnoid barrier layer is a part of the arachnoid meningeal layer. It is formed by tight junctions between the endothelial cells of cerebral capillaries in the arachnoid mater." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:UBERON_0014613 a rdfs:Class ;
rdfs:label "cervical spinal cord gray matter" ;
rdfs:comment "A gray matter of spinal cord that is part of a cervical spinal cord." ;
rdfs:subClassOf obo:UBERON_0002315 .
obo:CHEBI_75787 a rdfs:Class ;
rdfs:label "prokaryotic metabolite" ;
rdfs:comment "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:CL_0002653 a rdfs:Class ;
rdfs:label "squamous endothelial cell" ;
rdfs:comment "A squamous shaped endothelial cell." ;
rdfs:subClassOf obo:CL_0000115 .
obo:CHEBI_228364 a rdfs:Class ;
rdfs:label "NMR chemical shift reference compound" ;
rdfs:comment "Any compound that produces a peak used as reference frequency in the delta chemical shift scale." ;
rdfs:subClassOf obo:CHEBI_747204 .
obo:GO_1903441 a rdfs:Class ;
rdfs:label "protein localization to ciliary membrane" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a ciliary membrane." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0061512 , obo:GO_0072657 , obo:GO_1990778 .
obo:UBERON_0013686 a rdfs:Class ;
rdfs:label "anatomical conduit space" ;
rdfs:comment "An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:PHIPO_0000965 a rdfs:Class ;
rdfs:label "obsolete loss of virulence of gain of pathogenicity mutant" ;
rdfs:comment "A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is abolished when observed in an interaction with a pathogen mutant which was previously engineered to gain pathogenicity." .
obo:GO_0060438 a rdfs:Class ;
rdfs:label "trachea development" ;
rdfs:comment "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:GO_0004925 a rdfs:Class ;
rdfs:label "prolactin receptor activity" ;
rdfs:comment "Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0004896 , obo:GO_0038023 .
obo:PHIPO_0000527 a rdfs:Class ;
rdfs:label "resistance to enrofloxacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to enrofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_4052016 a rdfs:Class ;
rdfs:label "pituitary gland capillary endothelial cell" ;
rdfs:comment "A capillary endothelial cell that is part of the pituitary gland. This cell is characterized by its fenestrated structure which facilitates the efficient transport of hormones and other signaling molecules, essential for endocrine signalling." ;
rdfs:subClassOf obo:CL_0000666 , obo:CL_0002144 , obo:CL_2000004 , obo:CL_2000044 , obo:CL_4052015 .
obo:UBERON_0005248 a rdfs:Class ;
rdfs:label "bulbus cordis myocardium" ;
rdfs:comment "A myocardium that is part of a bulbus cordis [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002349 .
obo:GO_1904205 a rdfs:Class ;
rdfs:label "negative regulation of skeletal muscle hypertrophy" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy." ;
rdfs:subClassOf obo:GO_0014741 , obo:GO_0014745 , obo:GO_0065007 , obo:GO_1904204 .
obo:GO_1990625 a rdfs:Class ;
rdfs:label "negative regulation of cytoplasmic translational initiation in response to stress" ;
rdfs:comment "Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0032055 , obo:GO_0032057 , obo:GO_0065007 , obo:GO_1904689 , obo:GO_1990611 .
obo:CHEBI_26512 a rdfs:Class ;
rdfs:label "quinolinemonocarboxylic acid" ;
rdfs:comment "Any aromatic carboxylic acid that contains a quinoline moiety that is substituted by one carboxy substituent." ;
rdfs:subClassOf obo:CHEBI_26513 , obo:CHEBI_33859 .
obo:UBERON_0003834 a rdfs:Class ;
rdfs:label "thoracic segment blood vessel" ;
rdfs:comment "A blood vessel that is part of a thorax [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003513 .
obo:UBERON_0034907 a rdfs:Class ;
rdfs:label "pineal parenchyma" ;
rdfs:comment "Parenchymal tissue that forms the pineal gland." ;
rdfs:subClassOf obo:UBERON_0000353 , obo:UBERON_0005158 .
obo:GO_0055020 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle fiber development" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0055018 , obo:GO_0065007 , obo:GO_2000727 .
obo:GO_0030099 a rdfs:Class ;
rdfs:label "myeloid cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0001955 a rdfs:Class ;
rdfs:label "blood vessel maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:PHIPO_0000366 a rdfs:Class ;
rdfs:label "delayed timing of pathogen growth within host"@en ;
rdfs:comment "A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host begins later than normal." ;
rdfs:subClassOf obo:PHIPO_0000954 .
obo:GO_0003274 a rdfs:Class ;
rdfs:label "endocardial cushion fusion" ;
rdfs:comment "The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping." ;
rdfs:subClassOf obo:GO_0061343 , obo:GO_0098609 .
obo:UBERON_0011233 a rdfs:Class ;
rdfs:label "synovial membrane of synovial tendon sheath" ;
rdfs:comment "Synovial sac which surrounds parts of one or more tendons. Examples: synovial tendon sheath of manual digit 2, radial bursa." ;
rdfs:subClassOf obo:UBERON_0007616 .
obo:GO_0050777 a rdfs:Class ;
rdfs:label "negative regulation of immune response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ;
rdfs:subClassOf obo:GO_0002683 , obo:GO_0048585 , obo:GO_0050776 , obo:GO_0065007 .
obo:GO_0043255 a rdfs:Class ;
rdfs:label "regulation of carbohydrate biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates." ;
rdfs:subClassOf obo:GO_0006109 , obo:GO_0009889 , obo:GO_0065007 .
obo:GO_0060263 a rdfs:Class ;
rdfs:label "regulation of respiratory burst" ;
rdfs:comment "Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_0044782 a rdfs:Class ;
rdfs:label "cilium organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0016043 , obo:GO_0120036 .
obo:CL_0000232 a rdfs:Class ;
rdfs:label "erythrocyte" ;
rdfs:comment "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." ;
rdfs:subClassOf obo:CL_0000081 , obo:CL_0000329 , obo:CL_0000764 .
obo:UBERON_0003294 a rdfs:Class ;
rdfs:label "gland of foregut" ;
rdfs:comment "A gland that is part of a foregut [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002530 , obo:UBERON_0003408 .
obo:UBERON_0000957 a rdfs:Class ;
rdfs:label "lamina" ;
rdfs:comment "Any thin layer or plate." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:GO_0032274 a rdfs:Class ;
rdfs:label "gonadotropin secretion" ;
rdfs:comment "The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone." ;
rdfs:subClassOf obo:GO_0046879 .
obo:GO_1901879 a rdfs:Class ;
rdfs:label "regulation of protein depolymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein depolymerization." ;
rdfs:subClassOf obo:GO_0043244 , obo:GO_0065007 .
obo:GO_1905962 a rdfs:Class ;
rdfs:label "glutamatergic neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030182 .
obo:PHIPO_0000807 a rdfs:Class ;
rdfs:label "sensitive to triclabendazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to triclabendazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_2000283 a rdfs:Class ;
rdfs:label "negative regulation of amino acid biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0045763 , obo:GO_0065007 , obo:GO_2000282 .
obo:UBERON_0014541 a rdfs:Class ;
rdfs:label "thoracic division of spinal cord central canal" ;
rdfs:comment "Part of spinal cord central canal contained in the thoracic spinal cord. It is continuous rostrally with the cervical spinal cord central canal and caudally with the lumbar spinal cord central canal." ;
rdfs:subClassOf obo:UBERON_0014538 .
obo:OBI_0100026 a rdfs:Class .
obo:CHEBI_38623 a rdfs:Class ;
rdfs:label "EC 1.4.3.4 (monoamine oxidase) inhibitor" ;
rdfs:comment "An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4)." ;
rdfs:subClassOf obo:CHEBI_76861 .
obo:GO_1902213 a rdfs:Class ;
rdfs:label "positive regulation of prolactin signaling pathway" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway." ;
rdfs:subClassOf obo:GO_0001961 , obo:GO_0065007 , obo:GO_1902211 .
obo:UBERON_0003855 a rdfs:Class ;
rdfs:label "gonad mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a developing gonad [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005156 .
obo:CL_0000221 a rdfs:Class ;
rdfs:label "ectodermal cell" ;
rdfs:comment "A cell of the outer of the three germ layers of the embryo." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0002321 .
obo:GO_0009570 a rdfs:Class ;
rdfs:label "chloroplast stroma" ;
rdfs:comment "The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis." ;
rdfs:subClassOf obo:GO_0009532 .
obo:UBERON_0003559 a rdfs:Class ;
rdfs:label "hindbrain arachnoid mater" ;
rdfs:comment "An arachnoid mater that is part of a hindbrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002362 , obo:UBERON_0003291 .
obo:GO_0099157 a rdfs:Class ;
rdfs:label "trans-synaptic signaling via exosome" ;
rdfs:comment "Transynaptic signaling in which the ligand is carried across the synapse by an exosome." ;
rdfs:subClassOf obo:GO_0099156 , obo:GO_0099537 .
obo:UBERON_0002457 a rdfs:Class ;
rdfs:label "intersomitic artery" ;
rdfs:comment "The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0014907 .
obo:UBERON_0005673 a rdfs:Class ;
rdfs:label "left lung endothelium" ;
rdfs:comment "An endothelium that is part of a left lung." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0003365 .
obo:GO_0061051 a rdfs:Class ;
rdfs:label "positive regulation of cell growth involved in cardiac muscle cell development" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." ;
rdfs:subClassOf obo:GO_0010613 , obo:GO_0030307 , obo:GO_0051155 , obo:GO_0055023 , obo:GO_0061050 , obo:GO_0065007 .
obo:GO_0021508 a rdfs:Class ;
rdfs:label "floor plate formation" ;
rdfs:comment "The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PHIPO_0000707 a rdfs:Class ;
rdfs:label "resistance to hymexazol"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to hymexazol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0005403 a rdfs:Class ;
rdfs:label "ventral striatum" ;
rdfs:comment "A composite structure of the telencephalon that is defined in the striatopallidal system by connectivity and neurochemical staining. It includes the nucleus accumbens, the most ventral portions of the caudate nucleus and the putamen, the rostrolateral portion of the anterior perforated substance, the islands of Calleja and a rostral subcommissural portion of substantia innominata. The boundary between the ventral striatum and dorsal striatum is indistinct in sections stained for Nissl substance (Heimer-1995; adapted from Brain Info)." ;
rdfs:subClassOf obo:UBERON_0011300 .
obo:CHEBI_16215 a rdfs:Class ;
rdfs:label "phosphonate(2-)" ;
rdfs:comment "A divalent inorganic anion obtained by removal of both protons from phosphonic acid" ;
rdfs:subClassOf obo:CHEBI_33461 , obo:CHEBI_79388 .
obo:GO_0009653 a rdfs:Class ;
rdfs:label "anatomical structure morphogenesis" ;
rdfs:comment "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." ;
rdfs:subClassOf obo:GO_0032502 .
obo:GO_0006024 a rdfs:Class ;
rdfs:label "glycosaminoglycan biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units." ;
rdfs:subClassOf obo:GO_0006023 , obo:GO_0009058 , obo:GO_0030203 .
obo:GO_0170035 a rdfs:Class ;
rdfs:label "L-amino acid catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of an L-amino acid." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0009063 , obo:GO_0046395 , obo:GO_0170033 .
obo:CL_0000051 a rdfs:Class ;
rdfs:label "common lymphoid progenitor" ;
rdfs:comment "A oligopotent progenitor cell committed to the lymphoid lineage." ;
rdfs:subClassOf obo:CL_0002032 , obo:CL_0011026 .
obo:PR_P31996 a rdfs:Class ;
rdfs:label "macrosialin (mouse)" ;
rdfs:comment "A macrosialin that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000002064 , obo:PR_000029032 .
obo:GO_0021885 a rdfs:Class ;
rdfs:label "forebrain cell migration" ;
rdfs:comment "The orderly movement of a cell from one site to another at least one of which is located in the forebrain." ;
rdfs:subClassOf obo:GO_0016477 .
obo:GO_0002260 a rdfs:Class ;
rdfs:label "lymphocyte homeostasis" ;
rdfs:comment "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." ;
rdfs:subClassOf obo:GO_0001776 , obo:GO_0048872 .
obo:UBERON_0004121 a rdfs:Class ;
rdfs:label "ectoderm-derived structure" ;
rdfs:comment "An anatomical structure that develops (entirely or partially) from the ectoderm." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:PHIPO_0000847 a rdfs:Class ;
rdfs:label "sensitive to posaconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to posaconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_57560 a rdfs:Class ;
rdfs:label "long-chain fatty acid anion" ;
rdfs:comment "A fatty acid anion with a chain length of C13 to C22." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:GO_1990351 a rdfs:Class ;
rdfs:label "transporter complex" ;
rdfs:comment "A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells." ;
rdfs:subClassOf obo:GO_0032991 .
obo:GO_0000266 a rdfs:Class ;
rdfs:label "mitochondrial fission" ;
rdfs:comment "The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments." ;
rdfs:subClassOf obo:GO_0007005 , obo:GO_0048285 .
obo:GO_0048749 a rdfs:Class ;
rdfs:label "compound eye development" ;
rdfs:comment "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye." ;
rdfs:subClassOf obo:GO_0001654 , obo:GO_0048856 .
obo:GO_0050766 a rdfs:Class ;
rdfs:label "positive regulation of phagocytosis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of phagocytosis." ;
rdfs:subClassOf obo:GO_0045807 , obo:GO_0050764 , obo:GO_0065007 .
obo:GO_0042063 a rdfs:Class ;
rdfs:label "gliogenesis" ;
rdfs:comment "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia." ;
rdfs:subClassOf obo:GO_0008150 , obo:GO_0022008 .
obo:CHEBI_15339 a rdfs:Class ;
rdfs:label "acceptor" ;
rdfs:comment "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:UBERON_0002048 a rdfs:Class ;
rdfs:label "lung" ;
rdfs:comment "Respiration organ that develops as an outpocketing of the esophagus." ;
rdfs:subClassOf obo:UBERON_0000171 , obo:UBERON_0005178 , obo:UBERON_0015212 .
obo:CHEBI_35285 a rdfs:Class ;
rdfs:label "iminium betaine" ;
rdfs:subClassOf obo:CHEBI_26469 , obo:CHEBI_35281 .
obo:CHEBI_46786 a rdfs:Class ;
rdfs:label "diether" ;
rdfs:comment "A polyether in which the number of ether linkages is 2." ;
rdfs:subClassOf obo:CHEBI_46774 .
obo:CHEBI_83365 a rdfs:Class ;
rdfs:label "2,6-dimethyl-4-tridecylmorpholine" ;
rdfs:comment "A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a tridecyl group. The configuration at positions 2 and 6 is unknown or unspecified." ;
rdfs:subClassOf obo:CHEBI_38785 , obo:CHEBI_50996 .
obo:UBERON_0004490 a rdfs:Class ;
rdfs:label "cardiac muscle tissue of atrium" ;
rdfs:comment "A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001133 , obo:UBERON_0004493 .
obo:CHEBI_81913 a rdfs:Class ;
rdfs:label "diniconazole" ;
rdfs:comment "A racemate comprising equimolar amounts of (R)- and (S)-diniconazole. A fungicide used to control a range of diseases including mildew, bunts and smuts." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87067 , obo:CHEBI_87100 .
obo:CHEBI_33433 a rdfs:Class ;
rdfs:label "monoatomic halogen" ;
rdfs:subClassOf obo:CHEBI_33238 .
obo:GO_0045600 a rdfs:Class ;
rdfs:label "positive regulation of fat cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0045598 , obo:GO_0065007 .
obo:CHEBI_38231 a rdfs:Class ;
rdfs:label "phytotoxin" ;
rdfs:comment "Any toxin produced by a plant." ;
rdfs:subClassOf obo:CHEBI_27026 , obo:CHEBI_76924 .
obo:CHEBI_83735 a rdfs:Class ;
rdfs:label "(S)-vinclozolin" ;
rdfs:comment "A 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione that is the (S)-enantiomer of vinclozolin." ;
rdfs:subClassOf obo:CHEBI_83732 .
obo:CHEBI_26045 a rdfs:Class ;
rdfs:label "phosphite ion" ;
rdfs:subClassOf obo:CHEBI_33461 .
obo:GO_0120111 a rdfs:Class ;
rdfs:label "neuron projection cytoplasm" ;
rdfs:comment "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." ;
rdfs:subClassOf obo:GO_0005737 .
obo:PHIPO_0001121 a rdfs:Class ;
rdfs:label "abnormal sexual reproductive structure development"@en ;
rdfs:comment "A single species phenotype where the sexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is abnormal (GO:0048608)." ;
rdfs:subClassOf obo:PHIPO_0000043 .
obo:PHIPO_0000473 a rdfs:Class ;
rdfs:label "presence of pathogen asexual spores within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000472 .
obo:GO_0014061 a rdfs:Class ;
rdfs:label "regulation of norepinephrine secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine." ;
rdfs:subClassOf obo:GO_0050433 , obo:GO_0065007 .
obo:CHEBI_35695 a rdfs:Class ;
rdfs:label "dicarboxylic acid monoanion" ;
rdfs:comment "Any dicarboxylic acid anion that is a monoanion obtained by the deprotonation of only one of the carboxy groups of the dicarboxylic acid." ;
rdfs:subClassOf obo:CHEBI_35693 .
obo:GO_0001776 a rdfs:Class ;
rdfs:label "leukocyte homeostasis" ;
rdfs:comment "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0048872 .
obo:CHEBI_79389 a rdfs:Class ;
rdfs:label "monovalent inorganic anion" ;
rdfs:comment "Any inorganic anion with a valency of one." ;
rdfs:subClassOf obo:CHEBI_24834 .
obo:GO_0030660 a rdfs:Class ;
rdfs:label "Golgi-associated vesicle membrane" ;
rdfs:comment "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0030659 , obo:GO_0098588 .
obo:PHIPO_0000258 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction transport" ;
rdfs:comment "A pathogen host interaction phenotype in which a specific transport process is abnormal." .
obo:CHEBI_59673 a rdfs:Class ;
rdfs:label "colistin B" ;
rdfs:subClassOf obo:CHEBI_25903 , obo:CHEBI_59062 .
obo:CHEBI_37958 a rdfs:Class ;
rdfs:label "dye" ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:CHEBI_28669 a rdfs:Class ;
rdfs:label "bacitracin" ;
rdfs:comment "A mixture of at least nine closely related homodetic cyclic peptides produced by Bacillus subtilis and B. licheniformis, which is particularly active against Gram-positive bacteria." ;
rdfs:subClassOf obo:CHEBI_60004 .
obo:CHEBI_17891 a rdfs:Class ;
rdfs:label "donor" ;
rdfs:comment "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:UBERON_0019143 a rdfs:Class ;
rdfs:label "intramuscular adipose tissue" ;
rdfs:comment "Adipose tissue which is located throughout skeletal muscle and is responsible for the marbling seen in certain cuts of beef. In humans, excess accumulation of intramuscular fat is associated with insulin resistance and type 2 diabetes." ;
rdfs:subClassOf obo:UBERON_0001013 .
obo:CHEBI_83414 a rdfs:Class ;
rdfs:label "alkyl sulfate(1-)" ;
rdfs:comment "An organosulfate oxoanion obtained by deprotonation of the sulfo group of any alkyl sulfate; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_58958 .
obo:CHEBI_35442 a rdfs:Class ;
rdfs:label "antiparasitic agent" ;
rdfs:comment "A substance used to treat or prevent parasitic infections." ;
rdfs:subClassOf obo:CHEBI_35441 .
obo:CL_4301584 a rdfs:Class ;
rdfs:label "CB Granule Glut_1 cerebellar granule cell (Mmus)" ;
rdfs:comment "A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Lmx1a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1154 CB Granule Glut_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300354 .
obo:UBERON_0000962 a rdfs:Class ;
rdfs:label "nerve of cervical vertebra" ;
rdfs:comment "The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0001780 .
obo:GO_0014745 a rdfs:Class ;
rdfs:label "negative regulation of muscle adaptation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation." ;
rdfs:subClassOf obo:GO_0043502 , obo:GO_0048585 , obo:GO_0051241 , obo:GO_0065007 .
obo:GO_0015816 a rdfs:Class ;
rdfs:label "glycine transport" ;
rdfs:comment "The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015804 , obo:GO_0046942 , obo:GO_0071705 .
obo:GO_0140149 a rdfs:Class ;
rdfs:label "non-collagenous component of interstitial matrix" ;
rdfs:comment "The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin." ;
rdfs:subClassOf obo:GO_0030312 .
obo:GO_0110011 a rdfs:Class ;
rdfs:label "regulation of basement membrane organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903053 .
obo:CHEBI_37734 a rdfs:Class ;
rdfs:label "phosphoric ester" ;
rdfs:subClassOf obo:CHEBI_26079 , obo:CHEBI_35701 .
obo:GO_1901135 a rdfs:Class ;
rdfs:label "carbohydrate derivative metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving carbohydrate derivative." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0071705 a rdfs:Class ;
rdfs:label "nitrogen compound transport" ;
rdfs:comment "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 .
obo:CL_2000070 a rdfs:Class ;
rdfs:label "optic choroid fibroblast" ;
rdfs:comment "Any fibroblast that is part of a optic choroid." ;
rdfs:subClassOf obo:CL_0000005 , obo:CL_0000057 , obo:CL_0000348 .
obo:CHEBI_32988 a rdfs:Class ;
rdfs:label "amide" ;
rdfs:comment "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l ≠ 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ;
rdfs:subClassOf obo:CHEBI_51143 .
obo:GO_0010559 a rdfs:Class ;
rdfs:label "regulation of glycoprotein biosynthetic process" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ;
rdfs:subClassOf obo:GO_0010556 , obo:GO_0065007 , obo:GO_1903018 .
obo:GO_0036520 a rdfs:Class ;
rdfs:label "astrocyte-dopaminergic neuron signaling" ;
rdfs:comment "Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron." ;
rdfs:subClassOf obo:GO_0007267 , obo:GO_0150098 .
obo:CHEBI_36835 a rdfs:Class ;
rdfs:label "3alpha-hydroxy steroid" ;
rdfs:comment "A 3-hydroxy steroid in which the 3-hydroxy substituent is in the α-position." ;
rdfs:subClassOf obo:CHEBI_35681 , obo:CHEBI_36834 .
obo:GO_0051168 a rdfs:Class ;
rdfs:label "nuclear export" ;
rdfs:comment "The directed movement of substances out of the nucleus." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0006913 , obo:GO_0010496 .
obo:GO_0140001 a rdfs:Class ;
rdfs:label "morula formation" ;
rdfs:comment "The initial formation of a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CL_4301603 a rdfs:Class ;
rdfs:label "Tanycyte NN_2 tanycyte (Mmus)" ;
rdfs:comment "A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Ccdc170 (Mmus), Nkx2-4 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1173 Tanycyte NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300362 .
obo:GO_1902531 a rdfs:Class ;
rdfs:label "regulation of intracellular signal transduction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of intracellular signal transduction." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0065007 .
obo:CHEBI_25558 a rdfs:Class ;
rdfs:label "organonitrogen heterocyclic antibiotic" ;
rdfs:subClassOf obo:CHEBI_24531 , obo:CHEBI_38101 .
obo:CHEBI_76964 a rdfs:Class ;
rdfs:label "Penicillium metabolite" ;
rdfs:comment "Any fungal metabolite produced during a metabolic reaction in Penicillium." ;
rdfs:subClassOf obo:CHEBI_76946 .
obo:CL_0000652 a rdfs:Class ;
rdfs:label "pinealocyte" ;
rdfs:comment "This cell type produces and secretes melatonin and forms the pineal parenchyma. Extending from each cell body, which has a spherical, oval or lobulated mucleus, are one or more tortuous basophilic processes, containing parallel microtubules known as synaptic ribbons. These processes end in expanded terminal buds near capillaries or less, frequently, ependymal cells of the pineal recess. The terminal buds contain granular endoplasmic reticulum, mitochondria and electron-dense cored vesicles, which store monoamines and polypeptide hormones, release of which appears to require sympathetic innervation." ;
rdfs:subClassOf obo:CL_0000150 , obo:CL_0000163 , obo:CL_0000710 , obo:CL_0002319 .
obo:PHIPO_0000083 a rdfs:Class ;
rdfs:label "obsolete abnormal asexual spore motility" .
obo:GO_0030901 a rdfs:Class ;
rdfs:label "midbrain development" ;
rdfs:comment "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_78787 a rdfs:Class ;
rdfs:label "dithiocarbamic acids" ;
rdfs:comment "Any organic acid in which both oxygens of a carbamic acid have been replaced by sulfur." ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_50492 , obo:CHEBI_64709 .
obo:GO_0004568 a rdfs:Class ;
rdfs:label "chitinase activity" ;
rdfs:comment "Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins." ;
rdfs:subClassOf obo:GO_0004553 .
obo:GO_0045229 a rdfs:Class ;
rdfs:label "external encapsulating structure organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell." ;
rdfs:subClassOf obo:GO_0016043 .
obo:PHIPO_0001144 a rdfs:Class ;
rdfs:label "decreased level of host defense-related RNA involved in a pathogen interaction"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host defense-related RNA usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001174 .
obo:GO_0048730 a rdfs:Class ;
rdfs:label "epidermis morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." ;
rdfs:subClassOf obo:GO_0002009 , obo:GO_0009653 .
obo:CHEBI_52206 a rdfs:Class ;
rdfs:label "biochemical role" ;
rdfs:comment "A biological role played by the molecular entity or part thereof within a biochemical context." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CL_0007004 a rdfs:Class ;
rdfs:label "premigratory neural crest cell" ;
rdfs:comment "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0011012 .
obo:GO_0000228 a rdfs:Class ;
rdfs:label "nuclear chromosome" ;
rdfs:comment "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." ;
rdfs:subClassOf obo:GO_0005694 .
obo:CL_1000492 a rdfs:Class ;
rdfs:label "mesothelial cell of parietal pleura" ;
rdfs:comment "A mesothelial cell that is part of the parietal pleura." ;
rdfs:subClassOf obo:CL_0000077 , obo:CL_1000491 .
obo:UBERON_0003835 a rdfs:Class ;
rdfs:label "abdominal segment blood vessel" ;
rdfs:comment "A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003513 .
obo:PHIPO_0000240 a rdfs:Class ;
rdfs:label "abnormal pathogen protein localization within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the localization of a pathogen protein in a host cell differs from normal." ;
rdfs:subClassOf obo:PHIPO_0000236 .
obo:CHEBI_51336 a rdfs:Class ;
rdfs:label "metal sulfate" ;
rdfs:comment "Sulfate salts where the cation is a metal ion." ;
rdfs:subClassOf obo:CHEBI_24840 .
obo:CHEBI_46770 a rdfs:Class ;
rdfs:label "pyrrolidinecarboxamide" ;
rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_38260 .
obo:CHEBI_27822 a rdfs:Class ;
rdfs:label "2-aminobenzimidazole" ;
rdfs:comment "A member of the class of benzimidazoles that is benzimidazole in which the hydrogen at position 2 is replaced by an amino group." ;
rdfs:subClassOf obo:CHEBI_22715 .
obo:UBERON_0003716 a rdfs:Class ;
rdfs:label "recurrent laryngeal nerve" ;
rdfs:comment "A branch of the vagus nerve that supplies motor function and sensation to the larynx (voice box). It travels within the endoneurium. It is the nerve of the 6th Branchial Arch." ;
rdfs:subClassOf obo:UBERON_0011779 , obo:UBERON_0035642 .
obo:GO_0033750 a rdfs:Class ;
rdfs:label "ribosome localization" ;
rdfs:comment "A process in which a ribosome is transported to, and/or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051640 .
obo:GO_0009790 a rdfs:Class ;
rdfs:label "embryo development" ;
rdfs:comment "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." ;
rdfs:subClassOf obo:GO_0007275 , obo:GO_0048856 .
obo:PHIPO_0001104 a rdfs:Class ;
rdfs:label "increased level of host defense-induced RNA"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host RNA usually present during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001263 .
obo:GO_0007613 a rdfs:Class ;
rdfs:label "memory" ;
rdfs:comment "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." ;
rdfs:subClassOf obo:GO_0007611 .
obo:PHIPO_0000146 a rdfs:Class ;
rdfs:label "normal DNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000143 .
obo:GO_0051034 a rdfs:Class ;
rdfs:label "tRNA transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 , obo:GO_0051033 .
obo:PHIPO_0000035 a rdfs:Class ;
rdfs:label "mutualism present" ;
rdfs:comment "A pathogen host phenotype where the mutualism phenotype is normal (i.e. the same as wild-type), and the wild-type interaction exhibits mutualism." ;
rdfs:subClassOf obo:PHIPO_0000039 .
obo:GO_0090087 a rdfs:Class ;
rdfs:label "regulation of peptide transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 .
obo:GO_2000671 a rdfs:Class ;
rdfs:label "regulation of motor neuron apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of motor neuron apoptotic process." ;
rdfs:subClassOf obo:GO_0043523 , obo:GO_0065007 .
obo:CHEBI_64911 a rdfs:Class ;
rdfs:label "antimitotic" ;
rdfs:comment "Any compound that inhibits cell division (mitosis)." ;
rdfs:subClassOf obo:CHEBI_52210 .
obo:CHEBI_4885 a rdfs:Class ;
rdfs:label "ethionamide" ;
rdfs:comment "A thiocarboxamide that is pyridine-4-carbothioamide substituted by an ethyl group at position 2. A prodrug that undergoes metabolic activation by conversion to the corresponding S-oxide." ;
rdfs:subClassOf obo:CHEBI_39173 , obo:CHEBI_47956 .
obo:GO_1902369 a rdfs:Class ;
rdfs:label "negative regulation of RNA catabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process." ;
rdfs:subClassOf obo:GO_0009895 , obo:GO_0051253 , obo:GO_0065007 .
obo:GO_0061880 a rdfs:Class ;
rdfs:label "regulation of anterograde axonal transport of mitochondrion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902513 .
obo:GO_0044093 a rdfs:Class ;
rdfs:label "positive regulation of molecular function" ;
rdfs:comment "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:GO_0030054 a rdfs:Class ;
rdfs:label "cell junction" ;
rdfs:comment "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0070234 a rdfs:Class ;
rdfs:label "positive regulation of T cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070230 , obo:GO_0070232 .
obo:UBERON_0005613 a rdfs:Class ;
rdfs:label "left dorsal aorta" ;
rdfs:subClassOf obo:UBERON_0000947 , obo:UBERON_0003513 .
obo:PHIPO_0000617 a rdfs:Class ;
rdfs:label "resistance to verapamil"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to verapamil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0001727 a rdfs:Class ;
rdfs:label "taste bud" ;
rdfs:comment "A specialized receptor organ that is a collection of cells spanning the gustatory epithelium." ;
rdfs:subClassOf obo:UBERON_0003212 , obo:UBERON_0004119 .
obo:GO_0048469 a rdfs:Class ;
rdfs:label "cell maturation" ;
rdfs:comment "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0048869 , obo:GO_0071695 .
obo:GO_1904606 a rdfs:Class ;
rdfs:label "fat cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a fat cell." ;
rdfs:subClassOf obo:GO_0006915 .
obo:GO_1901701 a rdfs:Class ;
rdfs:label "cellular response to oxygen-containing compound" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_1901700 .
obo:CL_4307107 a rdfs:Class ;
rdfs:label "MOL NN_4 Il33 mature myelinating oligodendrocyte (Mmus)" ;
rdfs:comment "A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Opalin (Mmus), Grm3 (Mmus), Gm5087 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Il33, Gm5087. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5287 MOL NN_4." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301614 .
obo:CL_0000049 a rdfs:Class ;
rdfs:label "common myeloid progenitor" ;
rdfs:comment "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." ;
rdfs:subClassOf obo:CL_0002032 .
obo:GO_0002011 a rdfs:Class ;
rdfs:label "morphogenesis of an epithelial sheet" ;
rdfs:comment "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells." ;
rdfs:subClassOf obo:GO_0002009 , obo:GO_0009653 .
obo:GO_0009404 a rdfs:Class ;
rdfs:label "toxin metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." ;
rdfs:subClassOf obo:GO_0019748 .
obo:CL_4301616 a rdfs:Class ;
rdfs:label "arachnoid barrier cell (Mmus)" ;
rdfs:comment "A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Thbd (Mmus), Ccn3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1186 ABC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4023097 .
obo:PR_000001002 a rdfs:Class ;
rdfs:label "CD19 molecule" ;
rdfs:comment "A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0003365 a rdfs:Class ;
rdfs:label "epithelium of left lung" ;
rdfs:comment "An epithelium that is part of a left lung [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000115 , obo:UBERON_0000483 .
obo:UBERON_0000344 a rdfs:Class ;
rdfs:label "mucosa" ;
rdfs:comment "A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:GO_0097120 a rdfs:Class ;
rdfs:label "receptor localization to synapse" ;
rdfs:comment "Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." ;
rdfs:subClassOf obo:GO_0031503 , obo:GO_0051179 .
obo:GO_0001706 a rdfs:Class ;
rdfs:label "endoderm formation" ;
rdfs:comment "The formation of the endoderm during gastrulation." ;
rdfs:subClassOf obo:GO_0001704 , obo:GO_0048646 .
obo:PHIPO_0000445 a rdfs:Class ;
rdfs:label "pathogen host interaction host lesion formation phenotype"@en ;
rdfs:comment "A phenotype that affects the process of host tissue death causing a host lesion induced by either the pathogen directly killing host tissue (e.g. cell wall degradation), or the host activating its own cell death pathways in defense." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:PHIPO_0000192 a rdfs:Class ;
rdfs:label "presence of host-defense induced lesion by host hypersensitive response"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense, is present." ;
rdfs:subClassOf obo:PHIPO_0000461 .
obo:UBERON_0004273 a rdfs:Class ;
rdfs:label "cartilaginous joint suture" ;
rdfs:comment "A cranial suture that is part of a cartilaginous joint [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003685 .
obo:GO_0060214 a rdfs:Class ;
rdfs:label "endocardium formation" ;
rdfs:comment "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ;
rdfs:subClassOf obo:GO_0048646 .
obo:UBERON_0003121 a rdfs:Class ;
rdfs:label "pharyngeal arch artery 4" ;
rdfs:comment "The vessels formed within the fourth pair of branchial arches in embryogenesis." ;
rdfs:subClassOf obo:UBERON_0004363 .
obo:CHEBI_75954 a rdfs:Class ;
rdfs:label "vancomycin aglycone zwitterion" ;
rdfs:comment "A peptide zwitterion obtained by transfer of a proton from the carboxy to the amino group of vancomycin aglycone." ;
rdfs:subClassOf obo:CHEBI_60466 .
obo:GO_0021605 a rdfs:Class ;
rdfs:label "cranial nerve maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." ;
rdfs:subClassOf obo:GO_0021682 , obo:GO_0021700 .
obo:CHEBI_47867 a rdfs:Class ;
rdfs:label "indicator" ;
rdfs:comment "Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:CHEBI_52651 a rdfs:Class ;
rdfs:label "leptomycin" ;
rdfs:comment "A complex, very long chain, polyunsaturated fatty acid whose core structure comprises 8-oxononadeca-2,10,12,16,18-pentaenoic acid having methyl substituents at positions 3, 5, 7, 9, 11 and 15 and a 3,6-dihydropyran-6-one-2-yl group at position 19." ;
rdfs:subClassOf obo:CHEBI_24654 , obo:CHEBI_25000 , obo:CHEBI_26208 , obo:CHEBI_27283 , obo:CHEBI_35819 , obo:CHEBI_59644 , obo:CHEBI_79020 .
obo:UBERON_0002371 a rdfs:Class ;
rdfs:label "bone marrow" ;
rdfs:comment "The soft tissue that fills the cavities of bones." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:GO_0032368 a rdfs:Class ;
rdfs:label "regulation of lipid transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 , obo:GO_1905952 .
obo:GO_0099640 a rdfs:Class ;
rdfs:label "axo-dendritic protein transport" ;
rdfs:comment "The directed movement of proteins along microtubules in neuron projections." ;
rdfs:subClassOf obo:GO_0008088 , obo:GO_0046907 , obo:GO_0098840 .
obo:UBERON_0010285 a rdfs:Class ;
rdfs:label "midbrain basal plate" ;
rdfs:comment "Portion of tissue that is dorsolateral to the floor plate and part of the midbrain." ;
rdfs:subClassOf obo:UBERON_0002020 .
obo:GO_0048389 a rdfs:Class ;
rdfs:label "intermediate mesoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." ;
rdfs:subClassOf obo:GO_0007498 , obo:GO_0048856 .
obo:UBERON_0005497 a rdfs:Class ;
rdfs:label "non-neural ectoderm" ;
rdfs:comment "Gene notes: One of the first genes to be expressed in nonneural ectoderm in amphioxus is BMP2/4 (Panopoulou et al. 1998). BMP2/4 homologues appear to have a very ancient role in distinguishing neural from nonneural ectoderm; in Drosophila as well as in amphioxus and vertebrates, BMP2/4 homologues are expressed in nonneural ectoderm and function in distinguishing neural from nonneural ectoderm (Francois & Bier, 1995 ; Sasai et al. 1995 ; Wilson & Hemmati-Brivanlou, 1995; Panopoulou et al. 1998). A change in level of BMP2/4 from very high in nonneural ectoderm to low in neural ectoderm appears to be a key factor in development of neural crest (Baker & Bronner-Fraser,1997a,1997b;Erickson&Reedy,1998;Marchantet al.1998 ;Selleck et al. 1998)." ;
rdfs:subClassOf obo:UBERON_0000479 , obo:UBERON_0004121 .
obo:GO_0110117 a rdfs:Class ;
rdfs:label "positive regulation of compound eye photoreceptor cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation." ;
rdfs:subClassOf obo:GO_0046534 , obo:GO_0065007 , obo:GO_0110116 .
obo:GO_1901033 a rdfs:Class ;
rdfs:label "positive regulation of response to reactive oxygen species" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901031 , obo:GO_1902884 .
obo:GO_0050793 a rdfs:Class ;
rdfs:label "regulation of developmental process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:GO_0019216 a rdfs:Class ;
rdfs:label "regulation of lipid metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080090 .
obo:GO_0010970 a rdfs:Class ;
rdfs:label "transport along microtubule" ;
rdfs:comment "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0007018 , obo:GO_0030705 , obo:GO_0099111 .
obo:UBERON_0011930 a rdfs:Class ;
rdfs:label "preganglionic parasympathetic fiber" ;
rdfs:comment "A cholinergic axonal fibers projecting from the CNS to a parasympathetic ganglion." ;
rdfs:subClassOf obo:UBERON_0006134 , obo:UBERON_0011925 .
obo:GO_1903540 a rdfs:Class ;
rdfs:label "establishment of protein localization to postsynaptic membrane" ;
rdfs:comment "The directed movement of a protein to a specific location in a postsynaptic membrane." ;
rdfs:subClassOf obo:GO_0045184 , obo:GO_0090150 , obo:GO_1903539 .
obo:PR_000000001 a rdfs:Class ;
rdfs:label "protein" ;
rdfs:comment "An amino acid chain that is canonically produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." ;
rdfs:subClassOf obo:CHEBI_33695 , obo:PR_000018263 , obo:PR_000064867 .
obo:GO_0009658 a rdfs:Class ;
rdfs:label "chloroplast organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast." ;
rdfs:subClassOf obo:GO_0009657 , obo:GO_0016043 .
obo:CHEBI_33484 a rdfs:Class ;
rdfs:label "chalcogen oxoacid" ;
rdfs:subClassOf obo:CHEBI_24833 .
obo:CHEBI_59777 a rdfs:Class ;
rdfs:label "ketal" ;
rdfs:comment "An acetal of formula R2C(OR)2 (R ≠ H) derived from a ketone by replacement of the oxo group by two hydrocarbyloxy groups. The class name 'ketals', once abandoned by IUPAC, has been reinstated as a subclass of acetals." ;
rdfs:subClassOf obo:CHEBI_59769 .
obo:GO_0036135 a rdfs:Class ;
rdfs:label "Schwann cell migration" ;
rdfs:comment "The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintenance and function." ;
rdfs:subClassOf obo:GO_0008347 , obo:GO_0016477 .
obo:GO_0001768 a rdfs:Class ;
rdfs:label "establishment of T cell polarity" ;
rdfs:comment "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell." ;
rdfs:subClassOf obo:GO_0001767 , obo:GO_0030010 .
obo:CL_4301573 a rdfs:Class ;
rdfs:label "DCO Il22 Gly-Gaba_3 cerebellar neuron (Mmus)" ;
rdfs:comment "A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Fat2 (Mmus), Slc6a5 (Mmus), Cgnl1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1143 DCO Il22 Gly-Gaba_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300348 .
obo:PHIPO_0000513 a rdfs:Class ;
rdfs:label "inviable population"@en ;
rdfs:comment "An organism population phenotype in which no organisms in the population are viable." ;
rdfs:subClassOf obo:PHIPO_0000514 .
obo:GO_0006835 a rdfs:Class ;
rdfs:label "dicarboxylic acid transport" ;
rdfs:comment "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0046942 .
obo:GO_0006401 a rdfs:Class ;
rdfs:label "RNA catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0016070 , obo:GO_0141188 .
obo:CHEBI_35381 a rdfs:Class ;
rdfs:label "monosaccharide" ;
rdfs:comment "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H‒[CHOH]n‒C(=O)[CHOH]m‒H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." ;
rdfs:subClassOf obo:CHEBI_16646 .
obo:CHEBI_48343 a rdfs:Class ;
rdfs:label "disulfide" ;
rdfs:comment "Compounds of structure RSSR'." ;
rdfs:subClassOf obo:CHEBI_26835 .
obo:CHEBI_26432 a rdfs:Class ;
rdfs:label "pyrimidine nucleobase" ;
rdfs:comment "A nucleobase whose skeleton is derived from pyrimidine." ;
rdfs:subClassOf obo:CHEBI_18282 , obo:CHEBI_39447 .
obo:GO_1901950 a rdfs:Class ;
rdfs:label "dense core granule transport" ;
rdfs:comment "The directed movement a dense core granule within a cell." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0016482 , obo:GO_0032253 , obo:GO_0051650 .
obo:CHEBI_60027 a rdfs:Class ;
rdfs:label "polymer" ;
rdfs:comment "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." ;
rdfs:subClassOf obo:CHEBI_60004 .
obo:CHEBI_18320 a rdfs:Class ;
rdfs:label "1,4-dithiothreitol" ;
rdfs:comment "The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol." ;
rdfs:subClassOf obo:CHEBI_23853 , obo:CHEBI_25189 .
obo:UBERON_0002333 a rdfs:Class ;
rdfs:label "pulmonary trunk" ;
rdfs:comment "An arterial trunk which is continuous with the heart and branches into the pulmonary arteries." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:CL_4310117 a rdfs:Class ;
rdfs:label "SN-VTR-HTH GATA3-TCF7L2 GABA GABAergic interneuron (Primate)" ;
rdfs:comment "A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR-HTH GATA3-TCF7L2 GABA." ;
rdfs:subClassOf obo:CL_0011005 .
obo:PR_Q9R1R0 a rdfs:Class ;
rdfs:label "LIM/homeobox protein Lhx6 (mouse)" ;
rdfs:comment "A LIM/homeobox protein Lhx6 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000029032 , obo:PR_000032533 .
obo:UBERON_0000990 a rdfs:Class ;
rdfs:label "reproductive system" ;
rdfs:comment "Anatomical system that has as its parts the organs concerned with reproduction." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:PHIPO_0001447 a rdfs:Class ;
rdfs:label "increased level of deoxynivalenol"@en ;
rdfs:comment "A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is increased." ;
rdfs:subClassOf obo:PHIPO_0001037 .
obo:UBERON_0005432 a rdfs:Class ;
rdfs:label "aortic sac" ;
rdfs:comment "The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0002050 , obo:UBERON_0003498 .
obo:CL_0008000 a rdfs:Class ;
rdfs:label "non-striated muscle cell" ;
rdfs:comment "Any muscle cell in which the fibers are not organised into sarcomeres." ;
rdfs:subClassOf obo:CL_0000187 .
obo:UBERON_0002522 a rdfs:Class ;
rdfs:label "tunica media" ;
rdfs:comment "The middle layer of an artery or vein. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0004797 .
obo:CHEBI_83813 a rdfs:Class ;
rdfs:label "proteinogenic amino acid" ;
rdfs:comment "Any of the 23 α-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:UBERON_0002443 a rdfs:Class ;
rdfs:label "choroidal blood vessel" ;
rdfs:comment "A blood vessel that is part of a choroid [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003496 .
obo:GO_0003413 a rdfs:Class ;
rdfs:label "chondrocyte differentiation involved in endochondral bone morphogenesis" ;
rdfs:comment "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." ;
rdfs:subClassOf obo:GO_0002062 .
obo:GO_0002472 a rdfs:Class ;
rdfs:label "macrophage antigen processing and presentation" ;
rdfs:comment "The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." ;
rdfs:subClassOf obo:GO_0019882 .
obo:GO_1904970 a rdfs:Class ;
rdfs:label "brush border assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border." ;
rdfs:subClassOf obo:GO_0022607 .
obo:GO_0072596 a rdfs:Class ;
rdfs:label "establishment of protein localization to chloroplast" ;
rdfs:comment "The directed movement of a protein to a specific location in a chloroplast." ;
rdfs:subClassOf obo:GO_0045184 , obo:GO_0072594 , obo:GO_0072598 .
obo:GO_0070013 a rdfs:Class ;
rdfs:label "intracellular organelle lumen" ;
rdfs:comment "An organelle lumen that is part of an intracellular organelle." ;
rdfs:subClassOf obo:GO_0031974 , obo:GO_0043233 .
obo:GO_0051326 a rdfs:Class ;
rdfs:label "telophase" ;
rdfs:comment "The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." ;
rdfs:subClassOf obo:GO_0022403 .
obo:GO_0033047 a rdfs:Class ;
rdfs:label "regulation of mitotic sister chromatid segregation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." ;
rdfs:subClassOf obo:GO_0033045 , obo:GO_0065007 .
obo:GO_0043576 a rdfs:Class ;
rdfs:label "regulation of respiratory gaseous exchange" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 .
obo:GO_0099111 a rdfs:Class ;
rdfs:label "microtubule-based transport" ;
rdfs:comment "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." ;
rdfs:subClassOf obo:GO_0006810 .
obo:UBERON_0007272 a rdfs:Class ;
rdfs:label "pectoral appendage skeleton" ;
rdfs:comment "Skeletal subdivision consisting of the anterior appendicular limb skeleton, excluding the pectoral girdle." ;
rdfs:subClassOf obo:UBERON_0010912 , obo:UBERON_0011582 .
obo:CHEBI_16189 a rdfs:Class ;
rdfs:label "sulfate" ;
rdfs:comment "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." ;
rdfs:subClassOf obo:CHEBI_33482 , obo:CHEBI_48154 , obo:CHEBI_79388 .
obo:CHEBI_32952 a rdfs:Class ;
rdfs:label "amine" ;
rdfs:comment "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:GO_0120263 a rdfs:Class ;
rdfs:label "positive regulation of heterochromatin organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of heterochromatin organization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120261 , obo:GO_1905269 .
obo:GO_0035148 a rdfs:Class ;
rdfs:label "tube formation" ;
rdfs:comment "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PHIPO_0000848 a rdfs:Class ;
rdfs:label "sensitive to cephalexin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cephalexin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0003083 a rdfs:Class ;
rdfs:label "trunk neural crest" ;
rdfs:comment "Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]." ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:GO_0005313 a rdfs:Class ;
rdfs:label "L-glutamate transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid." ;
rdfs:subClassOf obo:GO_0005310 , obo:GO_0015172 , obo:GO_0015179 , obo:GO_0022857 .
obo:GO_0072659 a rdfs:Class ;
rdfs:label "protein localization to plasma membrane" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0072657 , obo:GO_1990778 .
obo:GO_0044087 a rdfs:Class ;
rdfs:label "regulation of cellular component biogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:UBERON_0034874 a rdfs:Class ;
rdfs:label "air in respiratory system" ;
rdfs:comment "Any portion of gas located in a part of the respiratory system that is composed primarily of air." ;
rdfs:subClassOf obo:UBERON_0034873 , obo:UBERON_0034947 .
obo:CHEBI_37246 a rdfs:Class ;
rdfs:label "elemental sodium" ;
rdfs:subClassOf obo:CHEBI_26712 .
obo:GO_0006545 a rdfs:Class ;
rdfs:label "glycine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid." ;
rdfs:subClassOf obo:GO_0006544 , obo:GO_0009058 , obo:GO_0009070 , obo:GO_0170038 .
obo:UBERON_0007284 a rdfs:Class ;
rdfs:label "presumptive neural plate" ;
rdfs:comment "A presumptive structure that has the potential to develop into a neural plate." ;
rdfs:subClassOf obo:UBERON_0006598 , obo:UBERON_0016879 .
obo:UBERON_0010212 a rdfs:Class ;
rdfs:label "laryngeal apparatus" ;
rdfs:comment "Apparatus located between the lungs and the buccal cavity. This apparatus is composed of a pair of arytenoid cartilages that are supported by the cricoid ring." ;
rdfs:subClassOf obo:UBERON_0034921 .
obo:GO_0060896 a rdfs:Class ;
rdfs:label "neural plate pattern specification" ;
rdfs:comment "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate." ;
rdfs:subClassOf obo:GO_0007389 .
obo:UBERON_0001773 a rdfs:Class ;
rdfs:label "sclera" ;
rdfs:comment "Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:PHIPO_0000330 a rdfs:Class ;
rdfs:label "abnormal transporter activity"@en ;
rdfs:comment "A molecular function phenotype in which the observed rate of a specified transporter activity is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000409 , obo:PHIPO_0000413 .
obo:GO_0030239 a rdfs:Class ;
rdfs:label "myofibril assembly" ;
rdfs:comment "Formation of myofibrils, the repeating units of striated muscle." ;
rdfs:subClassOf obo:GO_0010927 , obo:GO_0022607 , obo:GO_0031032 , obo:GO_0097435 , obo:GO_0140694 .
obo:GO_1902810 a rdfs:Class ;
rdfs:label "negative regulation of skeletal muscle fiber differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation." ;
rdfs:subClassOf obo:GO_0010832 , obo:GO_0065007 , obo:GO_1902809 , obo:GO_2001015 .
obo:GO_1904809 a rdfs:Class ;
rdfs:label "regulation of dense core granule transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dense core granule transport." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0065007 .
obo:CHEBI_51217 a rdfs:Class ;
rdfs:label "fluorochrome" ;
rdfs:comment "A fluorescent dye used to stain biological specimens." ;
rdfs:subClassOf obo:CHEBI_51121 .
obo:GO_0045196 a rdfs:Class ;
rdfs:label "establishment or maintenance of neuroblast polarity" ;
rdfs:comment "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." ;
rdfs:subClassOf obo:GO_0007163 .
obo:GO_0140098 a rdfs:Class ;
rdfs:label "catalytic activity, acting on RNA" ;
rdfs:comment "Catalytic activity that acts to modify RNA." ;
rdfs:subClassOf obo:GO_0003824 , obo:GO_0140640 .
obo:UBERON_0001957 a rdfs:Class ;
rdfs:label "submucosa of bronchus" ;
rdfs:comment "A submucosa that is part of a bronchus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000009 , obo:UBERON_0004777 .
obo:GO_0060468 a rdfs:Class ;
rdfs:label "prevention of polyspermy" ;
rdfs:comment "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg." ;
rdfs:subClassOf obo:GO_0060467 .
obo:GO_0033036 a rdfs:Class ;
rdfs:label "macromolecule localization" ;
rdfs:comment "Any process in which a macromolecule is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051179 .
obo:UBERON_0010294 a rdfs:Class ;
rdfs:label "scleral endothelium" ;
rdfs:comment "An endothelium that is part of a sclera." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0010291 , obo:UBERON_0015808 .
obo:CHEBI_33708 a rdfs:Class ;
rdfs:label "amino-acid residue" ;
rdfs:comment "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:GO_0072676 a rdfs:Class ;
rdfs:label "lymphocyte migration" ;
rdfs:comment "The movement of a lymphocyte within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0071674 .
a rdfs:Class ;
rdfs:label "Pons" ;
rdfs:subClassOf , obo:UBERON_0000988 .
obo:PHIPO_0001096 a rdfs:Class ;
rdfs:label "resistance to stress"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to a specific stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die)." ;
rdfs:subClassOf obo:PHIPO_0001217 .
obo:GO_0031345 a rdfs:Class ;
rdfs:label "negative regulation of cell projection organization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ;
rdfs:subClassOf obo:GO_0031344 , obo:GO_0051129 , obo:GO_0065007 .
obo:CL_4307090 a rdfs:Class ;
rdfs:label "OPC NN_1 Rmi2 oligodendrocyte precursor cell (Mmus)" ;
rdfs:comment "A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Rmi2 (Mmus), Col27a1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Rmi2, Col27a1. These cells are located in the Hypothalamus, Midbrain, Pallidum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5270 OPC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300366 .
obo:CHEBI_63673 a rdfs:Class ;
rdfs:label "chemokine receptor 5 antagonist" ;
rdfs:comment "An antogonist that blocks chemokine receptor 5 (CCR5)." ;
rdfs:subClassOf obo:CHEBI_48706 .
obo:GO_0001556 a rdfs:Class ;
rdfs:label "oocyte maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0021700 , obo:GO_0048469 .
obo:UBERON_0003526 a rdfs:Class ;
rdfs:label "respiratory system capillary" ;
rdfs:comment "A capillary that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001982 , obo:UBERON_0003504 .
obo:PATO_0002146 a rdfs:Class ;
rdfs:label "virulence" ;
rdfs:comment "A quality inhering in a bearer by virtue of the severity of infectious disease caused by the bearer in a target organism." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:CHEBI_77733 a rdfs:Class ;
rdfs:label "2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile" ;
rdfs:comment "A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group." ;
rdfs:subClassOf obo:CHEBI_18379 , obo:CHEBI_35618 , obo:CHEBI_46774 , obo:CHEBI_50996 .
obo:CHEBI_145555 a rdfs:Class ;
rdfs:label "macropolylide" ;
rdfs:comment "Macrolides (macrocyclic lactones) in which the macrocyclic ring contains more than one ester linkage. Macropolylides include macrodiolides, macrotriolides, macrotetrolides and macropentolides, each containing di-, tri-, tetra-, and penta- ester linkages, respectively, in one macrocyclic ring. Macrocyclic lactones containing nitrogen in their skeletons (azamacrolides and macrolide lactams) and also containing oxazole or thiazole in their skeletons are known in nature." ;
rdfs:subClassOf obo:CHEBI_25106 .
obo:CL_4301595 a rdfs:Class ;
rdfs:label "Astro-TE NN_5 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Thbs4 (Mmus), Kcnk10 (Mmus), Pak1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1165 Astro-TE NN_5." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300359 .
obo:GO_0090278 a rdfs:Class ;
rdfs:label "negative regulation of peptide hormone secretion" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." ;
rdfs:subClassOf obo:GO_0002792 , obo:GO_0046888 , obo:GO_0065007 , obo:GO_0090276 .
obo:GO_0090596 a rdfs:Class ;
rdfs:label "sensory organ morphogenesis" ;
rdfs:comment "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:PHIPO_0000068 a rdfs:Class ;
rdfs:label "sexual spores increased in size"@en ;
rdfs:comment "A reproductive morphology phenotype where the size of the sexual spore is increased." ;
rdfs:subClassOf obo:PHIPO_0000071 .
obo:UBERON_0006595 a rdfs:Class ;
rdfs:label "presumptive endoderm" ;
rdfs:comment "Presumptive structure of the blastula that will develop into endoderm." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:UBERON_0010522 a rdfs:Class ;
rdfs:label "replacement element" ;
rdfs:comment "Skeletal element that forms as a replacement or substitution of another element or tissue." ;
rdfs:subClassOf obo:UBERON_0004765 .
obo:GO_0097449 a rdfs:Class ;
rdfs:label "astrocyte projection" ;
rdfs:comment "A prolongation or process extending from the soma of an astrocyte and wrapping around neurons." ;
rdfs:subClassOf obo:GO_0097386 , obo:GO_0120025 .
obo:PHIPO_0000434 a rdfs:Class ;
rdfs:label "abnormal catalytic activity"@en ;
rdfs:comment "A single species molecular function phenotype in which the observed rate or other catalytic property of a specified catalytic activity is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000413 , obo:PHIPO_0000432 .
obo:GO_0032091 a rdfs:Class ;
rdfs:label "negative regulation of protein binding" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding." ;
rdfs:subClassOf obo:GO_0043393 , obo:GO_0051100 , obo:GO_0065007 .
obo:UBERON_0003592 a rdfs:Class ;
rdfs:label "bronchus connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a bronchus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003580 .
obo:UBERON_0012275 a rdfs:Class ;
rdfs:label "meso-epithelium" ;
rdfs:comment "Epithelium that derives from the mesoderm. [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004120 .
obo:PHIPO_0000218 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction toxin biosynthetic process" ;
rdfs:comment "A pathogen host interaction phenotype in which the toxin biosynthetic process is abnormal (i.e. different than the wild type)." .
obo:GO_0061660 a rdfs:Class ;
rdfs:label "Atg12 ligase activity" ;
rdfs:comment "Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate." ;
rdfs:subClassOf obo:GO_0019777 , obo:GO_0061659 .
obo:GO_0010564 a rdfs:Class ;
rdfs:label "regulation of cell cycle process" ;
rdfs:comment "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ;
rdfs:subClassOf obo:GO_0051726 , obo:GO_0065007 .
obo:PHIPO_0000247 a rdfs:Class ;
rdfs:label "abolished pathogen protein localization to host nucleus"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the localization of a pathogen protein to the host nucleus is abolished." ;
rdfs:subClassOf obo:PHIPO_0000246 .
obo:PHIPO_0000259 a rdfs:Class ;
rdfs:label "normal protein transport"@en ;
rdfs:comment "A single organism cellular process phenotype in which protein transport is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000256 .
obo:GO_1904377 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to cell periphery" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903829 , obo:GO_1904375 .
obo:CHEBI_83317 a rdfs:Class ;
rdfs:label "sterol biosynthesis inhibitor" ;
rdfs:comment "Any compound that inhibits the biosynthesis of any sterol." ;
rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 .
obo:CHEBI_25905 a rdfs:Class .
obo:CHEBI_28001 a rdfs:Class ;
rdfs:label "vancomycin" ;
rdfs:comment "A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile." ;
rdfs:subClassOf obo:CHEBI_24396 .
obo:GO_0099632 a rdfs:Class ;
rdfs:label "protein transport within plasma membrane" ;
rdfs:comment "A process in which protein is transported from one region of the plasma membrane to another." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0032594 .
obo:UBERON_0012429 a rdfs:Class ;
rdfs:label "hematopoietic tissue" ;
rdfs:comment "Blood-forming tissue, consisting of reticular fibers and cells." ;
rdfs:subClassOf obo:UBERON_0000479 , obo:UBERON_0034769 .
obo:CHEBI_59864 a rdfs:Class ;
rdfs:label "depigmentation drug" ;
rdfs:comment "Any drug used to depigment skin, normally by decreasing the excretion of melanin from melanocytes." ;
rdfs:subClassOf obo:CHEBI_23888 .
a rdfs:Class ;
rdfs:label "CHST9" ;
rdfs:subClassOf obo:SO_0000704 .
obo:GO_0035265 a rdfs:Class ;
rdfs:label "organ growth" ;
rdfs:comment "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function." ;
rdfs:subClassOf obo:GO_0032501 , obo:GO_0048589 .
obo:PR_000001024 a rdfs:Class ;
rdfs:label "neural cell adhesion molecule 1" ;
rdfs:comment "A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001023 .
obo:GO_0043363 a rdfs:Class ;
rdfs:label "nucleate erythrocyte differentiation" ;
rdfs:comment "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030218 .
obo:CHEBI_35508 a rdfs:Class ;
rdfs:label "steroid fundamental parent" ;
rdfs:subClassOf obo:CHEBI_35341 , obo:CHEBI_35507 .
obo:UBERON_0002209 a rdfs:Class ;
rdfs:label "fibrous joint" ;
rdfs:comment "Nonsynovial joint in which the articulating bones or cartilages are connected by ligaments. Examples: sagittal suture, inferior tibiofibular syndesmosis, gomphosis.[FMA]." ;
rdfs:subClassOf obo:UBERON_0011134 .
obo:UBERON_0013514 a rdfs:Class ;
rdfs:label "space surrounding organism" ;
rdfs:comment "The space that surrounds an organism." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0099513 a rdfs:Class ;
rdfs:label "polymeric cytoskeletal fiber" ;
rdfs:comment "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." ;
rdfs:subClassOf obo:GO_0099512 .
obo:GO_1901202 a rdfs:Class ;
rdfs:label "negative regulation of extracellular matrix assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901201 , obo:GO_1903054 .
obo:CHEBI_50995 a rdfs:Class ;
rdfs:label "secondary amino compound" ;
rdfs:comment "A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:GO_0008285 a rdfs:Class ;
rdfs:label "negative regulation of cell population proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0048523 , obo:GO_0065007 .
obo:PHIPO_0001417 a rdfs:Class ;
rdfs:label "resistance to penflufen" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to penflufen. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0099574 a rdfs:Class ;
rdfs:label "regulation of protein catabolic process at synapse, modulating synaptic transmission" ;
rdfs:comment "Any process that modulates synaptic transmission by regulating protein degradation at the synapse." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 , obo:GO_0140250 .
obo:UBERON_0002328 a rdfs:Class ;
rdfs:label "notochord" ;
rdfs:comment "A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0000481 , obo:UBERON_0004121 .
obo:CHEBI_88184 a rdfs:Class ;
rdfs:label "metal allergen" ;
rdfs:comment "Any metal which causes the onset of an allergic reaction." ;
rdfs:subClassOf obo:CHEBI_33521 .
obo:UBERON_0006538 a rdfs:Class ;
rdfs:label "respiratory system fluid/secretion" ;
rdfs:comment "A portion of organism substance that secreted_by a respiratory system." ;
rdfs:subClassOf obo:UBERON_0000463 .
obo:GO_0021514 a rdfs:Class ;
rdfs:label "ventral spinal cord interneuron differentiation" ;
rdfs:comment "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0021515 , obo:GO_0021953 , obo:GO_0030154 .
obo:PHIPO_0000899 a rdfs:Class ;
rdfs:label "sensitive to sordarin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to sordarin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_18379 a rdfs:Class ;
rdfs:label "nitrile" ;
rdfs:comment "A compound having the structure RC≡N; thus a C-substituted derivative of hydrocyanic acid, HC≡N. In systematic nomenclature, the suffix nitrile denotes the triply bound ≡N atom, not the carbon atom attached to it." ;
rdfs:subClassOf obo:CHEBI_23424 .
obo:GO_2000384 a rdfs:Class ;
rdfs:label "negative regulation of ectoderm development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0065007 , obo:GO_2000383 .
obo:GO_0006915 a rdfs:Class ;
rdfs:label "apoptotic process" ;
rdfs:comment "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." ;
rdfs:subClassOf obo:GO_0012501 .
obo:GO_0061040 a rdfs:Class ;
rdfs:label "female gonad morphogenesis" ;
rdfs:comment "The process in which a female gonad is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0035262 .
obo:CL_1000272 a rdfs:Class ;
rdfs:label "lung secretory cell" ;
rdfs:comment "Any secretory cell that is part of some lung." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000255 .
obo:CL_0002591 a rdfs:Class ;
rdfs:label "smooth muscle cell of the pulmonary artery" ;
rdfs:comment "A smooth muscle of the pulmonary artery." ;
rdfs:subClassOf obo:CL_0000359 , obo:CL_0019018 .
obo:UBERON_0036290 a rdfs:Class ;
rdfs:label "myocardium of anterior wall of left ventricle" ;
rdfs:subClassOf obo:UBERON_0002349 , obo:UBERON_0006566 .
obo:PHIPO_0000442 a rdfs:Class ;
rdfs:label "normal pathogen asexual reproduction within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host where the pathogen asexual reproduction process, in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is normal (indistinguishable from wild type)(GO:0019954)." ;
rdfs:subClassOf obo:PHIPO_0000440 .
obo:UBERON_0003388 a rdfs:Class ;
rdfs:label "mesothelium of pericardial cavity" ;
rdfs:comment "A mesothelium that is part of a pericardium [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001136 .
obo:UBERON_0009127 a rdfs:Class ;
rdfs:label "epibranchial ganglion" ;
rdfs:comment "Cranial ganglion which develops from an epibranchial placode." ;
rdfs:subClassOf obo:UBERON_0001714 , obo:UBERON_0004121 .
obo:CHEBI_35472 a rdfs:Class ;
rdfs:label "anti-inflammatory drug" ;
rdfs:comment "A substance that reduces or suppresses inflammation." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_67079 .
obo:CL_4307036 a rdfs:Class ;
rdfs:label "Astro-NT NN_2 Fam227b astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc7a10 (Mmus), Cyp26b1 (Mmus), Igfbp2 (Mmus), Shroom3 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Fam227b, Shroom3. These cells are located in the Midbrain, Medulla, Pons . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5216 Astro-NT NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301590 .
obo:GO_0048368 a rdfs:Class ;
rdfs:label "lateral mesoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0007498 , obo:GO_0048856 , obo:GO_0060485 .
obo:CHEBI_16670 a rdfs:Class ;
rdfs:label "peptide" ;
rdfs:comment "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from α-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ;
rdfs:subClassOf obo:CHEBI_37622 , obo:CHEBI_50047 .
obo:PHIPO_0001368 a rdfs:Class ;
rdfs:label "normal growth on carboxin" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to carboxin (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_184381 a rdfs:Class ;
rdfs:label "bacitracin A zwitterion" ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:GO_0050728 a rdfs:Class ;
rdfs:label "negative regulation of inflammatory response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response." ;
rdfs:subClassOf obo:GO_0031348 , obo:GO_0032102 , obo:GO_0050727 , obo:GO_0065007 .
obo:GO_1904340 a rdfs:Class ;
rdfs:label "positive regulation of dopaminergic neuron differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation." ;
rdfs:subClassOf obo:GO_0045666 , obo:GO_0065007 , obo:GO_1904338 .
obo:GO_0016051 a rdfs:Class ;
rdfs:label "carbohydrate biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." ;
rdfs:subClassOf obo:GO_0005975 , obo:GO_0009058 .
obo:PHIPO_0000200 a rdfs:Class ;
rdfs:label "host chlorosis phenotype in presence of pathogen"@en ;
rdfs:comment "A pathogen-host interaction phenotype in which leaves produce insufficient chlorophyll." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:PHIPO_0000423 a rdfs:Class ;
rdfs:label "decreased carbohydrate binding"@en ;
rdfs:comment "A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000419 .
obo:CHEBI_3534 a rdfs:Class ;
rdfs:label "cephalexin" ;
rdfs:comment "A semisynthetic first-generation cephalosporin antibiotic having methyl and β-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract." ;
rdfs:subClassOf obo:CHEBI_23066 , obo:CHEBI_72588 , obo:CHEBI_88225 .
obo:CHEBI_55346 a rdfs:Class ;
rdfs:label "anidulafungin" ;
rdfs:comment "A semisynthetic echinocandin anti-fungal drug. It is active against Aspergillus and Candida species and is used for the treatment of invasive candidiasis." ;
rdfs:subClassOf obo:CHEBI_24533 , obo:CHEBI_52898 , obo:CHEBI_57248 , obo:CHEBI_72588 , obo:CHEBI_87113 .
obo:GO_0002184 a rdfs:Class ;
rdfs:label "cytoplasmic translational termination" ;
rdfs:comment "The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon." ;
rdfs:subClassOf obo:GO_0006415 .
obo:CL_0008022 a rdfs:Class ;
rdfs:label "endocardial cushion cell" ;
rdfs:comment "A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves." ;
rdfs:subClassOf obo:CL_0000569 , obo:CL_0002494 .
obo:CHEBI_23447 a rdfs:Class ;
rdfs:label "cyclic nucleotide" ;
rdfs:subClassOf obo:CHEBI_36976 .
obo:CL_4310110 a rdfs:Class ;
rdfs:label "SN EBF2 GABA GABAergic interneuron (Primate)" ;
rdfs:comment "A GABAergic interneuron of the Primates brain. These cells are located in the striatum, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN EBF2 GABA." ;
rdfs:subClassOf obo:CL_0011005 , obo:CL_4310056 .
obo:CHEBI_37622 a rdfs:Class ;
rdfs:label "carboxamide" ;
rdfs:comment "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." ;
rdfs:subClassOf obo:CHEBI_33256 , obo:CHEBI_35352 , obo:CHEBI_36963 .
obo:PHIPO_0000792 a rdfs:Class ;
rdfs:label "sensitive to linezolid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to linezolid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0006311 a rdfs:Class ;
rdfs:label "chamber of eyeball" ;
rdfs:comment "A segment of the eyeball that is filled with refractive media." ;
rdfs:subClassOf obo:UBERON_0000063 .
obo:PHIPO_0000609 a rdfs:Class ;
rdfs:label "resistance to nalidixic acid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to nalidixic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1904140 a rdfs:Class ;
rdfs:label "negative regulation of microglial cell migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903976 , obo:GO_1904139 , obo:GO_1905522 .
obo:PHIPO_0000404 a rdfs:Class ;
rdfs:label "abnormal cell phenotype" ;
rdfs:comment "A phenotype that shows detectable differences from normal at the level of an individual cell." ;
rdfs:subClassOf obo:PHIPO_0000034 .
obo:CL_0000860 a rdfs:Class ;
rdfs:label "classical monocyte" ;
rdfs:comment "A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes." ;
rdfs:subClassOf obo:CL_0000576 .
obo:CHEBI_75596 a rdfs:Class ;
rdfs:label "EC 5.* (isomerase) inhibitor" ;
rdfs:comment "An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*)." ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:PHIPO_0001335 a rdfs:Class ;
rdfs:label "resistance to myclobutanil"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to myclobutanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:NCBITaxon_4751 a rdfs:Class ;
rdfs:label "Fungi" ;
rdfs:subClassOf obo:NCBITaxon_33154 .
obo:GO_1905459 a rdfs:Class ;
rdfs:label "regulation of vascular associated smooth muscle cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." ;
rdfs:subClassOf obo:GO_0034391 , obo:GO_0065007 .
obo:PATO_0070015 a rdfs:Class ;
rdfs:label "pyramidal family morphology" ;
rdfs:comment "A cell morphology that inheres in neurons which have a pyramidal shaped soma, a single axon, a large apical dendrite and multiple basal dendrites." ;
rdfs:subClassOf obo:PATO_0070026 .
obo:GO_0004978 a rdfs:Class ;
rdfs:label "corticotropin receptor activity" ;
rdfs:comment "Combining with corticotropin to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0004977 , obo:GO_0008188 , obo:GO_0038023 .
obo:CHEBI_64577 a rdfs:Class ;
rdfs:label "flour treatment agent" ;
rdfs:comment "A food additive which is added to flour or dough to improve baking quality and/or colour." ;
rdfs:subClassOf obo:CHEBI_64047 .
obo:UBERON_0011332 a rdfs:Class ;
rdfs:label "extrinsic tongue pre-muscle mass" ;
rdfs:subClassOf obo:UBERON_0005865 .
obo:GO_0045963 a rdfs:Class ;
rdfs:label "negative regulation of dopamine metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ;
rdfs:subClassOf obo:GO_0033239 , obo:GO_0042053 , obo:GO_0065007 .
obo:UBERON_0007389 a rdfs:Class ;
rdfs:label "paired limb/fin cartilage" ;
rdfs:comment "A cartilage tissue that is part of a paired limb or fin." ;
rdfs:subClassOf obo:UBERON_0002418 .
obo:UBERON_0010427 a rdfs:Class ;
rdfs:label "ciliary processes" ;
rdfs:comment "The ciliary processes are formed by the inward folding of the various layers of the choroid, i.e. , the choroid proper and the lamina basalis, and are received between corresponding foldings of the suspensory ligament of the lens." ;
rdfs:subClassOf obo:UBERON_0000481 .
obo:GO_0007276 a rdfs:Class ;
rdfs:label "gamete generation" ;
rdfs:comment "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." ;
rdfs:subClassOf obo:GO_0048609 .
obo:GO_1904688 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translational initiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0065007 , obo:GO_2000765 .
obo:PATO_0001407 a rdfs:Class ;
rdfs:label "mononucleate" ;
rdfs:comment "A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus." ;
rdfs:subClassOf obo:PATO_0002505 .
obo:CL_2000001 a rdfs:Class ;
rdfs:label "peripheral blood mononuclear cell" ;
rdfs:comment "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." ;
rdfs:subClassOf obo:CL_0000080 , obo:CL_0000842 .
obo:GO_0031334 a rdfs:Class ;
rdfs:label "positive regulation of protein-containing complex assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein complex assembly." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0044089 , obo:GO_0051130 , obo:GO_0065007 .
obo:CHEBI_88225 a rdfs:Class ;
rdfs:label "beta-lactam antibiotic allergen" ;
rdfs:comment "Any β-lactam antibiotic which causes the onset of an allergic reaction." ;
rdfs:subClassOf obo:CHEBI_27933 .
obo:CL_0000084 a rdfs:Class ;
rdfs:label "T cell" ;
rdfs:comment "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." ;
rdfs:subClassOf obo:CL_0000542 .
obo:CHEBI_35243 a rdfs:Class ;
rdfs:label "serine zwitterion" ;
rdfs:comment "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of serine." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:UBERON_0003947 a rdfs:Class ;
rdfs:label "brain ventricle/choroid plexus" ;
rdfs:comment "The brain ventricles or their associated choroid plexuses." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:UBERON_0009480 a rdfs:Class ;
rdfs:label "endoderm of buccopharyngeal membrane" ;
rdfs:comment "An endoderm that is part of a buccopharyngeal membrane." ;
rdfs:subClassOf obo:UBERON_0000925 .
obo:GO_0031340 a rdfs:Class ;
rdfs:label "positive regulation of vesicle fusion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vesicle fusion." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0031338 , obo:GO_0051050 , obo:GO_0065007 .
obo:GO_0034390 a rdfs:Class ;
rdfs:label "smooth muscle cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0010657 .
obo:GO_0061035 a rdfs:Class ;
rdfs:label "regulation of cartilage development" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000026 .
obo:GO_0006887 a rdfs:Class ;
rdfs:label "exocytosis" ;
rdfs:comment "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." ;
rdfs:subClassOf obo:GO_0016192 , obo:GO_0032940 .
obo:UBERON_0006834 a rdfs:Class ;
rdfs:label "uterus or analog" ;
rdfs:comment "A subdivision of a the reproductive tract in a female organism that is the site of embryo development." ;
rdfs:subClassOf obo:UBERON_0005156 , obo:UBERON_0013522 .
obo:GO_0042670 a rdfs:Class ;
rdfs:label "retinal cone cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0060219 .
obo:UBERON_0003081 a rdfs:Class ;
rdfs:label "lateral plate mesoderm" ;
rdfs:comment "Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0004120 , obo:UBERON_0005291 , obo:UBERON_0007524 .
obo:CHEBI_29919 a rdfs:Class ;
rdfs:label "hydrosulfide" ;
rdfs:subClassOf obo:CHEBI_33535 .
obo:GO_0048390 a rdfs:Class ;
rdfs:label "intermediate mesoderm morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the intermediate mesoderm are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048332 .
obo:GO_0035914 a rdfs:Class ;
rdfs:label "skeletal muscle cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_1904018 a rdfs:Class ;
rdfs:label "positive regulation of vasculature development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vasculature development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1901342 .
obo:GO_0031111 a rdfs:Class ;
rdfs:label "negative regulation of microtubule polymerization or depolymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." ;
rdfs:subClassOf obo:GO_0031110 , obo:GO_0051494 , obo:GO_0065007 .
obo:UBERON_0009615 a rdfs:Class ;
rdfs:label "midbrain hindbrain boundary neural plate" ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0006598 .
obo:UBERON_0000158 a rdfs:Class ;
rdfs:label "membranous layer" ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:PR_000007489 a rdfs:Class ;
rdfs:label "fibroblast growth factor 2" ;
rdfs:comment "A protein that is a translation product of the human FGF2 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_1903427 a rdfs:Class ;
rdfs:label "negative regulation of reactive oxygen species biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0065007 , obo:GO_1903426 , obo:GO_2000378 .
obo:UBERON_0001796 a rdfs:Class ;
rdfs:label "aqueous humor of eyeball" ;
rdfs:comment "A thick watery refractive medium that fills the space between the lens and the cornea[WP]." ;
rdfs:subClassOf obo:UBERON_0006312 , obo:UBERON_0006314 .
obo:GO_1905873 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to cell leading edge" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903829 , obo:GO_1905871 .
obo:GO_0006448 a rdfs:Class ;
rdfs:label "regulation of translational elongation" ;
rdfs:comment "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:GO_0061736 a rdfs:Class ;
rdfs:label "engulfment of target by autophagosome" ;
rdfs:comment "The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy." ;
rdfs:subClassOf obo:GO_0010324 .
obo:CL_4310131 a rdfs:Class ;
rdfs:label "STR D1D2 Hybrid MSN D1/D2-hybrid medium spiny neuron (Primate)" ;
rdfs:comment "A D1/D2-hybrid medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR D1D2 Hybrid MSN." ;
rdfs:subClassOf obo:CL_4030050 .
obo:GO_0090070 a rdfs:Class ;
rdfs:label "positive regulation of ribosome biogenesis" ;
rdfs:comment "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." ;
rdfs:subClassOf obo:GO_0044089 , obo:GO_0065007 , obo:GO_0090069 .
obo:GO_0021626 a rdfs:Class ;
rdfs:label "central nervous system maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:GO_0032411 a rdfs:Class ;
rdfs:label "positive regulation of transporter activity" ;
rdfs:comment "Any process that activates or increases the activity of a transporter." ;
rdfs:subClassOf obo:GO_0044093 , obo:GO_0051050 , obo:GO_0065007 .
obo:GO_0032774 a rdfs:Class ;
rdfs:label "RNA biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." ;
rdfs:subClassOf obo:GO_0009059 , obo:GO_0016070 , obo:GO_0141187 .
obo:GO_0032065 a rdfs:Class ;
rdfs:label "maintenance of protein location in cell cortex" ;
rdfs:comment "A process in which a protein or protein complex is maintained in a specific location in the cell cortex." ;
rdfs:subClassOf obo:GO_0032507 , obo:GO_0045185 .
obo:GO_2000243 a rdfs:Class ;
rdfs:label "positive regulation of reproductive process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of reproductive process." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0065007 , obo:GO_2000241 .
obo:PATO_0000150 a rdfs:Class ;
rdfs:label "texture" ;
rdfs:comment "A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:CHEBI_33552 a rdfs:Class ;
rdfs:label "sulfonic acid derivative" ;
rdfs:subClassOf obo:CHEBI_33424 .
obo:GO_0060795 a rdfs:Class ;
rdfs:label "cell fate commitment involved in formation of primary germ layer" ;
rdfs:comment "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." ;
rdfs:subClassOf obo:GO_0045165 .
obo:GO_0042551 a rdfs:Class ;
rdfs:label "neuron maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0048469 .
obo:CHEBI_24470 a rdfs:Class ;
rdfs:label "haloamino acid" ;
rdfs:comment "Any non-proteinogenic amino acid carrying at least one halo group." ;
rdfs:subClassOf obo:CHEBI_83820 .
obo:GO_0098930 a rdfs:Class ;
rdfs:label "axonal transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules in axons." ;
rdfs:subClassOf obo:GO_0008088 , obo:GO_0046907 .
obo:GO_1900118 a rdfs:Class ;
rdfs:label "negative regulation of execution phase of apoptosis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0065007 , obo:GO_1900117 .
obo:GO_0032943 a rdfs:Class ;
rdfs:label "mononuclear cell proliferation" ;
rdfs:comment "The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0070661 .
obo:PATO_0000470 a rdfs:Class ;
rdfs:label "increased amount" ;
rdfs:comment "An amount which is relatively high." ;
rdfs:subClassOf obo:PATO_0000070 , obo:PATO_0000467 , obo:PATO_0002300 .
obo:CHEBI_33641 a rdfs:Class ;
rdfs:label "olefin" ;
rdfs:comment "Acyclic and cyclic hydrocarbons having one or more carbon-carbon double bonds, apart from the formal ones in aromatic compounds. The class olefins subsumes alkenes and cycloalkenes and the corresponding polyenes." ;
rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_78840 .
obo:CHEBI_27207 a rdfs:Class ;
rdfs:label "univalent carboacyl group" ;
rdfs:comment "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." ;
rdfs:subClassOf obo:CHEBI_37838 .
obo:GO_1905193 a rdfs:Class ;
rdfs:label "negative regulation of chloroplast fission" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0065007 , obo:GO_1905192 .
obo:GO_0045840 a rdfs:Class ;
rdfs:label "positive regulation of mitotic nuclear division" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitosis." ;
rdfs:subClassOf obo:GO_0007088 , obo:GO_0051785 , obo:GO_0065007 , obo:GO_0090068 .
obo:GO_0014911 a rdfs:Class ;
rdfs:label "positive regulation of smooth muscle cell migration" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration." ;
rdfs:subClassOf obo:GO_0014910 , obo:GO_0030335 , obo:GO_0065007 .
obo:GO_0048857 a rdfs:Class ;
rdfs:label "neural nucleus development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_17634 a rdfs:Class ;
rdfs:label "D-glucose" ;
rdfs:comment "A glucose with D-configuration." ;
rdfs:subClassOf obo:CHEBI_17234 , obo:CHEBI_17608 .
obo:UBERON_0002894 a rdfs:Class ;
rdfs:label "olfactory cortex" ;
rdfs:comment "Aggregate brain region defined as those areas of cerebral cortex receiving direct synaptic input from the olfactory bulb (Price, 1973). It usually includes the piriform cortex and sometimes other areas." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_0001578 a rdfs:Class ;
rdfs:label "microtubule bundle formation" ;
rdfs:comment "A process that results in a parallel arrangement of microtubules." ;
rdfs:subClassOf obo:GO_0000226 .
obo:GO_0046879 a rdfs:Class ;
rdfs:label "hormone secretion" ;
rdfs:comment "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." ;
rdfs:subClassOf obo:GO_0009914 , obo:GO_0023061 .
obo:GO_0010721 a rdfs:Class ;
rdfs:label "negative regulation of cell development" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0060284 , obo:GO_0065007 .
obo:UBERON_0001759 a rdfs:Class ;
rdfs:label "vagus nerve" ;
rdfs:comment "Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart)." ;
rdfs:subClassOf obo:UBERON_0001785 , obo:UBERON_0010314 .
obo:PATO_0070026 a rdfs:Class ;
rdfs:label "multipolar neuron morphology" ;
rdfs:comment "A cell morphology that inheres in neurons which possess three or more neurites, usually a single axon and many dendrites and dendritic branches." ;
rdfs:subClassOf obo:PATO_0010006 .
obo:PHIPO_0001346 a rdfs:Class ;
rdfs:label "sensitive to bitertanol" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to bitertanol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1905936 a rdfs:Class ;
rdfs:label "regulation of germ cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of germ cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0051239 , obo:GO_0065007 .
obo:CHEBI_33229 a rdfs:Class ;
rdfs:label "vitamin (role)" ;
rdfs:comment "A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term \"vitamines\" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines." ;
rdfs:subClassOf obo:CHEBI_27027 , obo:CHEBI_52206 .
obo:CHEBI_81783 a rdfs:Class ;
rdfs:label "tricyclazole" ;
rdfs:comment "A triazolobenzothiazole that is [1,2,4]triazolo[3,4-b][1,3]benzothiazole which is substituted at position 5 by a methyl group. A fungicide used for the control of rice blast, it is not approved for use within the European Union." ;
rdfs:subClassOf obo:CHEBI_48908 .
obo:UBERON_0000355 a rdfs:Class ;
rdfs:label "pharyngeal mucosa" ;
rdfs:comment "A mucosa that is part of a pharynx [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0004785 .
obo:CL_0000038 a rdfs:Class ;
rdfs:label "erythroid progenitor cell" ;
rdfs:comment "A progenitor cell committed to the erythroid lineage." ;
rdfs:subClassOf obo:CL_0000764 , obo:CL_0000839 .
obo:GO_1903226 a rdfs:Class ;
rdfs:label "positive regulation of endodermal cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0065007 , obo:GO_1903224 .
obo:UBERON_0010257 a rdfs:Class ;
rdfs:label "6th arch mesenchyme from neural crest" ;
rdfs:comment "Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0010031 , obo:UBERON_0010258 , obo:UBERON_0010359 .
obo:CHEBI_39232 a rdfs:Class ;
rdfs:label "emamectin B1b" ;
rdfs:subClassOf obo:CHEBI_50346 .
obo:CHEBI_51371 a rdfs:Class ;
rdfs:label "muscle relaxant" ;
rdfs:comment "A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis." ;
rdfs:subClassOf obo:CHEBI_51372 .
obo:PHIPO_0000502 a rdfs:Class ;
rdfs:label "obsolete decreased level of deoxynivalenol" ;
rdfs:comment "A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is lower than normal." .
obo:GO_1904748 a rdfs:Class ;
rdfs:label "regulation of apoptotic process involved in development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of apoptotic process involved in development." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0050793 , obo:GO_0065007 .
obo:PHIPO_0000377 a rdfs:Class ;
rdfs:label "resistance to carboxin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to carboxin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000272 a rdfs:Class ;
rdfs:label "normal pathogen protein localization to host nucleus"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the localization of a pathogen protein to the host nucleus is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001175 .
obo:PHIPO_0000836 a rdfs:Class ;
rdfs:label "sensitive to rifampicin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to rifampicin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_39446 a rdfs:Class ;
rdfs:label "pyrimidine ribonucleosides" ;
rdfs:subClassOf obo:CHEBI_18254 , obo:CHEBI_26440 .
obo:CHEBI_39215 a rdfs:Class ;
rdfs:label "antibiotic pesticide" ;
rdfs:subClassOf obo:CHEBI_25944 , obo:CHEBI_33281 .
obo:PHIPO_0001250 a rdfs:Class ;
rdfs:label "abnormal host structure induced by pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype where the development of a host structure is abnormal during pathogen infection." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:BFO_0000019 a rdfs:Class ;
rdfs:label "quality"@en ;
rdfs:subClassOf obo:BFO_0000020 .
obo:CL_0000990 a rdfs:Class ;
rdfs:label "conventional dendritic cell" ;
rdfs:comment "Conventional dendritic cell is a dendritic cell that is CD11c-high." ;
rdfs:subClassOf obo:CL_0000451 .
obo:GO_0009889 a rdfs:Class ;
rdfs:label "regulation of biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_0099538 a rdfs:Class ;
rdfs:label "synaptic signaling via neuropeptide" ;
rdfs:comment "Cell-cell signaling to or from a synapse, mediated by a peptide." ;
rdfs:subClassOf obo:GO_0099536 .
obo:PATO_0002045 a rdfs:Class ;
rdfs:label "dendritic" ;
rdfs:comment "A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure." ;
rdfs:subClassOf obo:PATO_0000402 .
obo:UBERON_0001899 a rdfs:Class ;
rdfs:label "epithalamus" ;
rdfs:comment "Most dorsal part of the thalamus, comprising the pineal gland and habenular nuclei in most vertebrates. In a few vertebrates, it also includes the parietal eye. (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed, 2005, pg. 345-346." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:PHIPO_0001380 a rdfs:Class ;
rdfs:label "normal growth on tacrolimus" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to tacrolimus (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PHIPO_0000636 a rdfs:Class ;
rdfs:label "resistance to diniconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to diniconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_25865 a rdfs:Class ;
rdfs:label "penicillanic acids" ;
rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_35992 .
obo:UBERON_0007646 a rdfs:Class ;
rdfs:label "endomeninx" ;
rdfs:comment "The innermost layer of the mesenchymal capsule that surrounds the developing brain, primarily of neural crest origin. The endomeninx forms the leptomeninx." ;
rdfs:subClassOf obo:UBERON_0007645 .
obo:UBERON_0001896 a rdfs:Class ;
rdfs:label "medulla oblongata" ;
rdfs:comment "Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:GO_0003279 a rdfs:Class ;
rdfs:label "cardiac septum development" ;
rdfs:comment "The progression of a cardiac septum over time, from its initial formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0030720 a rdfs:Class ;
rdfs:label "oocyte localization involved in germarium-derived egg chamber formation" ;
rdfs:comment "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051674 .
obo:GO_0120178 a rdfs:Class ;
rdfs:label "steroid hormone biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." ;
rdfs:subClassOf obo:GO_0006694 .
obo:PHIPO_0000625 a rdfs:Class ;
rdfs:label "resistance to posaconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to posaconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CLM_1000085 a rdfs:Class ;
rdfs:label "NS forest marker set of VIP GABAergic interneuron (Human neocortex)." ;
rdfs:subClassOf obo:SO_0001260 .
obo:GO_0061147 a rdfs:Class ;
rdfs:label "endocardial endothelium development" ;
rdfs:comment "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ;
rdfs:subClassOf obo:GO_0003158 , obo:GO_0048856 .
obo:PHIPO_0000395 a rdfs:Class ;
rdfs:label "sensitive to terbinafine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to terbinafine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0034905 a rdfs:Class ;
rdfs:label "gland lumen" ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:UBERON_0035551 a rdfs:Class ;
rdfs:label "deep vasculature" ;
rdfs:comment "The part of the circulatory system that lies deep beneath the subcutaneous tissue layers away from the surface of the skin." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:PHIPO_0001340 a rdfs:Class ;
rdfs:label "resistance to nocodazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to nocodazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PR_Q62226 a rdfs:Class ;
rdfs:label "sonic hedgehog protein (mouse)" ;
rdfs:comment "A sonic hedgehog protein that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000014841 , obo:PR_000029032 .
obo:GO_1901699 a rdfs:Class ;
rdfs:label "cellular response to nitrogen compound" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_1901698 .
obo:UBERON_0002148 a rdfs:Class ;
rdfs:label "locus ceruleus" ;
rdfs:comment "The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]." ;
rdfs:subClassOf obo:UBERON_0006331 , obo:UBERON_0009662 , obo:UBERON_8440015 .
obo:UBERON_0002301 a rdfs:Class ;
rdfs:label "layer of neocortex" ;
rdfs:comment "One of the layers of the neocortex. These layers are defined by distinctive populations of cells based on somata size, shape, or density, that are aligned into sheets." ;
rdfs:subClassOf obo:UBERON_0022303 , obo:UBERON_8440004 .
obo:CHEBI_50903 a rdfs:Class ;
rdfs:label "carcinogenic agent" ;
rdfs:comment "A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:GO_0021687 a rdfs:Class ;
rdfs:label "cerebellar molecular layer morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0023056 a rdfs:Class ;
rdfs:label "positive regulation of signaling" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." ;
rdfs:subClassOf obo:GO_0023051 , obo:GO_0048518 , obo:GO_0065007 .
obo:CL_0000706 a rdfs:Class ;
rdfs:label "choroid plexus epithelial cell" ;
rdfs:comment "A specialized ependymal cell that is part of the choroid plexus epithelium, responsible for producing cerebrospinal fluid (CSF) by selectively filtering and modifying blood plasma components before secreting it into the brain and spinal cord. This cell is characterized by a brush border on its apical surface, which enhances the secretion of CSF." ;
rdfs:subClassOf obo:CL_0000065 , obo:CL_0000239 .
obo:UBERON_0011822 a rdfs:Class ;
rdfs:label "dense irregular connective tissue" ;
rdfs:comment "Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium." ;
rdfs:subClassOf obo:UBERON_0011821 , obo:UBERON_0011823 .
obo:CL_0002664 a rdfs:Class ;
rdfs:label "cardioblast" ;
rdfs:comment "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart." ;
rdfs:subClassOf obo:CL_0000048 .
obo:GO_0019954 a rdfs:Class ;
rdfs:label "asexual reproduction" ;
rdfs:comment "A type of reproduction in which new individuals are produced from a single organism, either from an unfertilized egg or from a single cell or group of cells." ;
rdfs:subClassOf obo:GO_0022414 .
obo:CHEBI_5827 a rdfs:Class ;
rdfs:label "hymexazol" ;
rdfs:comment "A member of the class of isoxazoles carrying hydroxy and methyl substituents at positions 3 and 5 respectively. It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. in rice, sugarbeet, fodderbeet, vegetables, cucurbits, and ornamentals." ;
rdfs:subClassOf obo:CHEBI_55373 , obo:CHEBI_74818 .
obo:PHIPO_0000346 a rdfs:Class ;
rdfs:label "obsolete host necrotic lesion with pathogen phenotype" .
obo:GO_1904817 a rdfs:Class ;
rdfs:label "serous membrane development" ;
rdfs:comment "The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0060907 a rdfs:Class ;
rdfs:label "positive regulation of macrophage cytokine production" ;
rdfs:comment "Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0010935 , obo:GO_0061081 , obo:GO_0065007 .
obo:GO_0030323 a rdfs:Class ;
rdfs:label "respiratory tube development" ;
rdfs:comment "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract." ;
rdfs:subClassOf obo:GO_0035295 , obo:GO_0048513 , obo:GO_0048856 .
obo:GO_0008291 a rdfs:Class ;
rdfs:label "acetylcholine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ;
rdfs:subClassOf obo:GO_0008152 .
obo:PR_000007499 a rdfs:Class ;
rdfs:label "fibroblast growth factor 8" ;
rdfs:comment "A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0015204 a rdfs:Class ;
rdfs:label "glandular system" ;
rdfs:comment "A non-connected functional system that is composed primarily of a gland." ;
rdfs:subClassOf obo:UBERON_0015203 .
obo:CHEBI_32066 a rdfs:Class ;
rdfs:label "Prothionamide" ;
rdfs:subClassOf obo:CHEBI_39173 .
obo:PHIPO_0000859 a rdfs:Class ;
rdfs:label "sensitive to micafungin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to micafungin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0003072 a rdfs:Class ;
rdfs:label "optic cup" ;
rdfs:comment "Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0004121 .
obo:CHEBI_3508 a rdfs:Class ;
rdfs:label "ceftazidime" ;
rdfs:comment "A third-generation cephalosporin antibiotic bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton." ;
rdfs:subClassOf obo:CHEBI_23066 , obo:CHEBI_36816 .
obo:GO_0061527 a rdfs:Class ;
rdfs:label "dopamine secretion, neurotransmission" ;
rdfs:comment "The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0007269 , obo:GO_0099124 , obo:GO_0160043 .
obo:GO_0061725 a rdfs:Class ;
rdfs:label "cytosolic lipolysis" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0016042 .
obo:CHEBI_65077 a rdfs:Class ;
rdfs:label "neomycin C(6+)" ;
rdfs:comment "An organic cation obtained by protonation of the six free amino groups of neomycin C; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:UBERON_0004710 a rdfs:Class ;
rdfs:label "pectoral appendage" ;
rdfs:comment "Paired appendage that consists of the anterior appendicular skeleton and associated soft and hard tissues, but excludes the pectoral girdle and its associated soft and hard tissues." ;
rdfs:subClassOf obo:UBERON_0004708 .
obo:UBERON_0000203 a rdfs:Class ;
rdfs:label "pallium" ;
rdfs:comment "Dorsal part (roof region) of the telencephalon[GO]." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:UBERON_0005334 a rdfs:Class ;
rdfs:label "oral lamina propria" ;
rdfs:comment "A lamina propria that is part of a mucosa of oral region." ;
rdfs:subClassOf obo:UBERON_0000030 .
obo:GO_0009987 a rdfs:Class ;
rdfs:label "cellular process" ;
rdfs:comment "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_1901137 a rdfs:Class ;
rdfs:label "carbohydrate derivative biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of carbohydrate derivative." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_1901135 .
obo:GO_0032223 a rdfs:Class ;
rdfs:label "negative regulation of synaptic transmission, cholinergic" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ;
rdfs:subClassOf obo:GO_0032222 , obo:GO_0050805 , obo:GO_0065007 .
obo:CL_4310145 a rdfs:Class ;
rdfs:label "AMY-SLEA-BNST D1 GABA GABAergic interneuron (Primate)" ;
rdfs:comment "A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST D1 GABA." ;
rdfs:subClassOf obo:CL_0011005 .
obo:GO_0046395 a rdfs:Class ;
rdfs:label "carboxylic acid catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0019752 , obo:GO_0044282 .
obo:CL_0000214 a rdfs:Class ;
rdfs:label "synovial cell" ;
rdfs:comment "A cell located in the synovial joint." ;
rdfs:subClassOf obo:CL_0002078 .
obo:CHEBI_17522 a rdfs:Class ;
rdfs:label "alditol" ;
rdfs:comment "A carbohydrate that is an acyclic polyol having the general formula HOCH2[CH(OH)]nCH2OH (formally derivable from an aldose by reduction of the carbonyl group)." ;
rdfs:subClassOf obo:CHEBI_16646 , obo:CHEBI_26191 .
obo:GO_0016817 a rdfs:Class ;
rdfs:label "hydrolase activity, acting on acid anhydrides" ;
rdfs:comment "Catalysis of the hydrolysis of any acid anhydride." ;
rdfs:subClassOf obo:GO_0016787 .
obo:UBERON_0035815 a rdfs:Class ;
rdfs:label "paracardial fat" ;
rdfs:comment "Fat deposits in the mediastinum outside the parietal pericardium ." ;
rdfs:subClassOf obo:UBERON_0001013 , obo:UBERON_0035814 .
obo:GO_0006925 a rdfs:Class ;
rdfs:label "inflammatory cell apoptotic process" ;
rdfs:comment "Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage." ;
rdfs:subClassOf obo:GO_0006915 .
obo:UBERON_0005661 a rdfs:Class ;
rdfs:label "3rd arch ectoderm" ;
rdfs:comment "An ectoderm that is part of a pharyngeal arch 3." ;
rdfs:subClassOf obo:UBERON_0000924 .
obo:UBERON_0010009 a rdfs:Class ;
rdfs:label "aggregate regional part of brain" ;
rdfs:comment "A regional part of brain consisting of multiple brain regions that are not related through a simple volummetric part of hierarchy, e.g., basal ganglia[NIF]." ;
rdfs:subClassOf obo:UBERON_0034923 .
obo:UBERON_0000486 a rdfs:Class ;
rdfs:label "multilaminar epithelium" ;
rdfs:comment "Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_1903702 a rdfs:Class ;
rdfs:label "esophagus development" ;
rdfs:comment "The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0051632 a rdfs:Class ;
rdfs:label "negative regulation of acetylcholine uptake" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell." ;
rdfs:subClassOf obo:GO_0051631 , obo:GO_0051953 , obo:GO_0065007 .
obo:GO_1905209 a rdfs:Class ;
rdfs:label "positive regulation of cardiocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1905207 .
obo:GO_0048608 a rdfs:Class ;
rdfs:label "reproductive structure development" ;
rdfs:comment "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0048856 .
obo:PATO_0002505 a rdfs:Class ;
rdfs:label "nucleated" ;
rdfs:comment "A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus." ;
rdfs:subClassOf obo:PATO_0001404 .
obo:PR_000001969 a rdfs:Class ;
rdfs:label "urokinase plasminogen activator surface receptor" ;
rdfs:comment "A protein that is a translation product of the human PLAUR gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PR_000001839 a rdfs:Class ;
rdfs:label "T-cell surface glycoprotein CD5" ;
rdfs:comment "A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0004277 a rdfs:Class ;
rdfs:label "eye muscle" ;
rdfs:comment "A muscle that is part of the eye region." ;
rdfs:subClassOf obo:UBERON_0001630 .
obo:CHEBI_164200 a rdfs:Class ;
rdfs:label "triclosan" ;
rdfs:comment "An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes." ;
rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_33853 , obo:CHEBI_35618 , obo:CHEBI_83403 .
obo:GO_0008528 a rdfs:Class ;
rdfs:label "G protein-coupled peptide receptor activity" ;
rdfs:comment "Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." ;
rdfs:subClassOf obo:GO_0001653 , obo:GO_0004930 .
obo:PHIPO_0000606 a rdfs:Class ;
rdfs:label "resistance to rifampicin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to rifampicin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1904409 a rdfs:Class ;
rdfs:label "regulation of secretory granule organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of secretory granule organization." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:CL_0000861 a rdfs:Class ;
rdfs:label "elicited macrophage" ;
rdfs:comment "A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive." ;
rdfs:subClassOf obo:CL_0000235 .
obo:GO_0017157 a rdfs:Class ;
rdfs:label "regulation of exocytosis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of exocytosis." ;
rdfs:subClassOf obo:GO_0060627 , obo:GO_0065007 , obo:GO_1903530 .
obo:GO_0008347 a rdfs:Class ;
rdfs:label "glial cell migration" ;
rdfs:comment "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." ;
rdfs:subClassOf obo:GO_0016477 .
obo:PHIPO_0000079 a rdfs:Class ;
rdfs:label "normal sexual sporulation"@en ;
rdfs:comment "A reproductive phenotype where the process of sexual sporulation, the formation of spores from the products of meiosis, is normal (GO:0034293)." ;
rdfs:subClassOf obo:PHIPO_0000046 .
obo:CHEBI_51958 a rdfs:Class ;
rdfs:label "organic polycyclic compound" ;
rdfs:subClassOf obo:CHEBI_33635 , obo:CHEBI_33832 .
obo:CL_0011027 a rdfs:Class ;
rdfs:label "skeletal muscle fibroblast" ;
rdfs:comment "Any fibroblast that is part of skeletal muscle tissue." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0000188 , obo:CL_1001609 .
obo:GO_0030141 a rdfs:Class ;
rdfs:label "secretory granule" ;
rdfs:comment "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." ;
rdfs:subClassOf obo:GO_0099503 .
obo:PHIPO_0001174 a rdfs:Class ;
rdfs:label "decreased level of host defense-induced RNA"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host RNA usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001263 .
obo:GO_1901533 a rdfs:Class ;
rdfs:label "negative regulation of hematopoietic progenitor cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0065007 , obo:GO_1901532 .
obo:CHEBI_9168 a rdfs:Class ;
rdfs:label "sirolimus" ;
rdfs:comment "A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent." ;
rdfs:subClassOf obo:CHEBI_145565 , obo:CHEBI_25698 , obo:CHEBI_26979 , obo:CHEBI_35681 , obo:CHEBI_3992 , obo:CHEBI_59770 , obo:CHEBI_87113 .
obo:GO_1905673 a rdfs:Class ;
rdfs:label "positive regulation of lysosome organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lysosome organization." ;
rdfs:subClassOf obo:GO_0044090 , obo:GO_0065007 , obo:GO_1905671 .
obo:CL_0002557 a rdfs:Class ;
rdfs:label "fibroblast of pulmonary artery" ;
rdfs:comment "A fibroblast of pulmonary artery." ;
rdfs:subClassOf obo:CL_0000057 .
obo:CHEBI_22888 a rdfs:Class ;
rdfs:label "biphenyls" ;
rdfs:comment "Benzenoid aromatic compounds containing two phenyl or substituted-phenyl groups which are joined together by a single bond." ;
rdfs:subClassOf obo:CHEBI_33836 , obo:CHEBI_36820 , obo:CHEBI_64459 .
obo:PATO_0002255 a rdfs:Class ;
rdfs:label "grooved" ;
rdfs:comment "Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels." ;
rdfs:subClassOf obo:PATO_0000150 .
obo:GO_0070132 a rdfs:Class ;
rdfs:label "regulation of mitochondrial translational initiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0065007 , obo:GO_0070129 .
obo:PHIPO_0000825 a rdfs:Class ;
rdfs:label "sensitive to tebuconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tebuconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_73155 a rdfs:Class ;
rdfs:label "trienoic fatty acid" ;
rdfs:comment "Any polyunsaturated fatty acid that contains three double bonds." ;
rdfs:subClassOf obo:CHEBI_26208 , obo:CHEBI_53339 .
obo:UBERON_0011596 a rdfs:Class ;
rdfs:label "future lower lip" ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0003236 .
obo:GO_0001560 a rdfs:Class ;
rdfs:label "regulation of cell growth by extracellular stimulus" ;
rdfs:comment "Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time." ;
rdfs:subClassOf obo:GO_0001558 .
obo:GO_0048147 a rdfs:Class ;
rdfs:label "negative regulation of fibroblast proliferation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0048145 , obo:GO_0065007 .
obo:GO_0051668 a rdfs:Class ;
rdfs:label "localization within membrane" ;
rdfs:comment "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051641 .
obo:PHIPO_0000233 a rdfs:Class ;
rdfs:label "pathogen deoxynivalenol within host present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the pathogen produced deoxynivalenol usually present during infection is present as normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001043 .
obo:GO_0021843 a rdfs:Class ;
rdfs:label "substrate-independent telencephalic tangential interneuron migration" ;
rdfs:comment "The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates." ;
rdfs:subClassOf obo:GO_0021826 .
obo:PR_P01101 a rdfs:Class ;
rdfs:label "protein c-Fos (mouse)" ;
rdfs:comment "A protein c-Fos that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000007597 , obo:PR_000029032 .
obo:GO_0051179 a rdfs:Class ;
rdfs:label "localization" ;
rdfs:comment "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_0043232 a rdfs:Class ;
rdfs:label "intracellular membraneless organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." ;
rdfs:subClassOf obo:GO_0043228 , obo:GO_0043229 .
obo:GO_0043010 a rdfs:Class ;
rdfs:label "camera-type eye development" ;
rdfs:comment "The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." ;
rdfs:subClassOf obo:GO_0001654 , obo:GO_0048856 .
obo:CHEBI_25940 a rdfs:Class ;
rdfs:label "peroxides" ;
rdfs:comment "Compounds of structure ROOR'." ;
rdfs:subClassOf obo:CHEBI_25741 .
obo:CHEBI_35625 a rdfs:Class ;
rdfs:label "EC 3.5.2.6 (beta-lactamase) inhibitor" ;
rdfs:comment "An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of β-lactamase (EC 3.5.2.6)." ;
rdfs:subClassOf obo:CHEBI_76808 .
obo:GO_0043143 a rdfs:Class ;
rdfs:label "regulation of translation by machinery localization" ;
rdfs:comment "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0008104 .
obo:PATO_0001236 a rdfs:Class ;
rdfs:label "process quality" ;
rdfs:comment "A quality which inheres in an process." ;
rdfs:subClassOf obo:PATO_0000001 .
obo:PATO_0002309 a rdfs:Class ;
rdfs:label "fiber shaped" ;
rdfs:comment "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter." ;
rdfs:subClassOf obo:PATO_0002226 .
obo:UBERON_0002241 a rdfs:Class ;
rdfs:label "chondrocranium" ;
rdfs:comment "Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]." ;
rdfs:subClassOf obo:UBERON_0011159 .
obo:GO_0030217 a rdfs:Class ;
rdfs:label "T cell differentiation" ;
rdfs:comment "The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex." ;
rdfs:subClassOf obo:GO_0030098 , obo:GO_0030154 , obo:GO_0042110 .
obo:GO_0045321 a rdfs:Class ;
rdfs:label "leukocyte activation" ;
rdfs:comment "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0002376 .
obo:CHEBI_75381 a rdfs:Class ;
rdfs:label "EC 1.11.1.* (peroxidases) inhibitor" ;
rdfs:comment "An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*)." ;
rdfs:subClassOf obo:CHEBI_76738 .
obo:UBERON_0003727 a rdfs:Class ;
rdfs:label "intercostal nerve" ;
rdfs:comment "The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0001780 .
obo:UBERON_0005866 a rdfs:Class ;
rdfs:label "pre-cartilage condensation" ;
rdfs:comment "A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts." ;
rdfs:subClassOf obo:UBERON_0005291 , obo:UBERON_0005856 .
obo:CHEBI_25699 a rdfs:Class ;
rdfs:label "organic ion" ;
rdfs:subClassOf obo:CHEBI_24870 , obo:CHEBI_50860 .
obo:GO_0060841 a rdfs:Class ;
rdfs:label "venous blood vessel development" ;
rdfs:comment "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed." ;
rdfs:subClassOf obo:GO_0001568 , obo:GO_0048856 .
obo:GO_1905319 a rdfs:Class ;
rdfs:label "mesenchymal stem cell migration" ;
rdfs:comment "The orderly movement of a mesenchymal stem cell from one site to another." ;
rdfs:subClassOf obo:GO_0016477 .
obo:CHEBI_33861 a rdfs:Class ;
rdfs:label "transition element coordination entity" ;
rdfs:subClassOf obo:CHEBI_33240 , obo:CHEBI_33497 .
obo:PHIPO_0000056 a rdfs:Class ;
rdfs:label "premature sexual sporulation"@en ;
rdfs:comment "A reproductive phenotype in which the occurrence of sexual spore formation happens sooner than normal." ;
rdfs:subClassOf obo:PHIPO_0000077 .
obo:GO_0001937 a rdfs:Class ;
rdfs:label "negative regulation of endothelial cell proliferation" ;
rdfs:comment "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation." ;
rdfs:subClassOf obo:GO_0001936 , obo:GO_0050680 , obo:GO_0065007 .
obo:PHIPO_0001428 a rdfs:Class ;
rdfs:label "normal growth on brefeldin A"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to brefeldin A (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PHIPO_0000594 a rdfs:Class ;
rdfs:label "resistance to cefpodoxime proxetil"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cefpodoxime proxetil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001238 a rdfs:Class ;
rdfs:label "increased chitinase activity"@en ;
rdfs:comment "A single species molecular function phenotype in which the observed rate of chitinase activity is increased." ;
rdfs:subClassOf obo:PHIPO_0000437 .
obo:UBERON_0001979 a rdfs:Class ;
rdfs:label "venule" ;
rdfs:comment "One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins." ;
rdfs:subClassOf obo:UBERON_0003920 , obo:UBERON_8410081 .
obo:UBERON_0003473 a rdfs:Class ;
rdfs:label "thoracic cavity artery" ;
rdfs:comment "An artery that is part of a thoracic cavity[cjm]." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0003519 .
obo:UBERON_0001531 a rdfs:Class ;
rdfs:label "right common carotid artery plus branches" ;
rdfs:comment "The rightmost of the two common carotid arteries, originating from in the neck from the brachiocephalic trunk." ;
rdfs:subClassOf obo:UBERON_0001530 .
obo:UBERON_0014793 a rdfs:Class ;
rdfs:label "musculature of pectoral complex" ;
rdfs:comment "Any collection of muscles that is part of a pectoral complex. The pectoral complex comprises the pectoral girdle and the associated limb or fin." ;
rdfs:subClassOf obo:UBERON_0001015 .
obo:UBERON_0003023 a rdfs:Class ;
rdfs:label "pontine tegmentum" ;
rdfs:comment "Dorsal portion of the pons, containing cranial nervee nuclei, ascending and descending tracts and reticular nuclei. It is continuous with the reticular formation of the medulla (Carpenter, A Core Text of Neuroanatomy, 3rd ed, 1985, pg 133)." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:CHEBI_35411 a rdfs:Class ;
rdfs:label "alkane-alpha,omega-diamine" ;
rdfs:comment "A primary diamine that is ethane or a higher alkane in which a hydrogen of each of the terminal methyl groups has been replaced by an amino group. H2NCH2(CH2)nCH2NH2, where n = 0, 1, 2, etc." ;
rdfs:subClassOf obo:CHEBI_35410 , obo:CHEBI_46687 .
obo:GO_0021861 a rdfs:Class ;
rdfs:label "forebrain radial glial cell differentiation" ;
rdfs:comment "The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0060019 .
obo:GO_0014857 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:PHIPO_0001278 a rdfs:Class ;
rdfs:label "decreased pathogen induced host DNA synthesis"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the host DNA synthesis during pathogen infection occurs to a lesser extent than normal (GO:0090592 DNA synthesis involved in DNA replication)." ;
rdfs:subClassOf obo:PHIPO_0001247 .
obo:GO_1904073 a rdfs:Class ;
rdfs:label "regulation of trophectodermal cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0048638 , obo:GO_0065007 .
obo:CL_4042013 a rdfs:Class ;
rdfs:label "Lamp5 Lhx6 neuron"@en ;
rdfs:comment "A transcriptomically distinct GABAergic interneuron marked by Lamp5 and Lhx6 expression, derived from the Medial Ganglionic Eminence (MGE), and located in the pallium." ;
rdfs:subClassOf obo:CL_4023011 , obo:CL_4023069 .
obo:UBERON_8450003 a rdfs:Class ;
rdfs:label "embryonic craniocervical region" ;
rdfs:comment "A craniocervical region that is part of an embryo." ;
rdfs:subClassOf obo:UBERON_0007811 .
obo:PR_000015665 a rdfs:Class ;
rdfs:label "somatostatin" ;
rdfs:comment "A protein that is a translation product of the human SST gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_1904171 a rdfs:Class ;
rdfs:label "negative regulation of bleb assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120033 , obo:GO_1904170 .
obo:GO_0061462 a rdfs:Class ;
rdfs:label "protein localization to lysosome" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a lysosome." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0072665 .
obo:CHEBI_25703 a rdfs:Class ;
rdfs:label "organic phosphate" ;
rdfs:subClassOf obo:CHEBI_25710 , obo:CHEBI_26020 .
obo:UBERON_0001576 a rdfs:Class ;
rdfs:label "intrinsic muscle of tongue" ;
rdfs:comment "The intrinsic tongue muscles are an integral part of the tongue and completely contained within the tongue that are innervated by Cranial Nerve XII." ;
rdfs:subClassOf obo:UBERON_0000378 , obo:UBERON_0004120 , obo:UBERON_0014892 .
obo:GO_0003221 a rdfs:Class ;
rdfs:label "right ventricular cardiac muscle tissue morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0055010 .
obo:CHEBI_24473 a rdfs:Class ;
rdfs:label "halogen" ;
rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33560 .
obo:UBERON_0006239 a rdfs:Class ;
rdfs:label "future central tendon" ;
rdfs:comment "A tendon that has the potential to develop into a central tendon." ;
rdfs:subClassOf obo:UBERON_0000043 , obo:UBERON_0005291 , obo:UBERON_0006598 .
obo:GO_0046850 a rdfs:Class ;
rdfs:label "regulation of bone remodeling" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity." ;
rdfs:subClassOf obo:GO_0034103 , obo:GO_0065007 .
obo:GO_0048712 a rdfs:Class ;
rdfs:label "negative regulation of astrocyte differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045686 , obo:GO_0048710 , obo:GO_0065007 .
obo:UBERON_0000171 a rdfs:Class ;
rdfs:label "respiration organ" ;
rdfs:comment "Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:CHEBI_73754 a rdfs:Class ;
rdfs:label "thiosugar" ;
rdfs:comment "A carbohydrate derivative in which one or more of the oxygens or hydroxy groups of the parent carbohydrate is replaced by sulfur or -SR, where R can be hydrogen or any group." ;
rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_63299 .
obo:UBERON_0002360 a rdfs:Class ;
rdfs:label "meninx" ;
rdfs:comment "Membrane organ that surrounds the brain and the spinal cord." ;
rdfs:subClassOf obo:UBERON_0000094 , obo:UBERON_0004121 .
obo:GO_0160048 a rdfs:Class ;
rdfs:label "craniofacial suture closure" ;
rdfs:comment "The process of fusing together the edges of a craniofacial suture." ;
rdfs:subClassOf obo:GO_0060349 .
obo:GO_0021548 a rdfs:Class ;
rdfs:label "pons development" ;
rdfs:comment "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CL_0000562 a rdfs:Class ;
rdfs:label "nucleate erythrocyte" ;
rdfs:comment "An erythrocyte having a nucleus." ;
rdfs:subClassOf obo:CL_0000232 , obo:CL_0002242 .
obo:GO_0120025 a rdfs:Class ;
rdfs:label "plasma membrane bounded cell projection" ;
rdfs:comment "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." ;
rdfs:subClassOf obo:GO_0042995 .
obo:GO_0034293 a rdfs:Class ;
rdfs:label "sexual sporulation" ;
rdfs:comment "The formation of spores derived from the products of meiosis." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0043934 .
obo:CHEBI_76837 a rdfs:Class ;
rdfs:label "EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor" ;
rdfs:comment "An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*)." ;
rdfs:subClassOf obo:CHEBI_76740 .
obo:UBERON_0022351 a rdfs:Class ;
rdfs:label "parietal serous membrane" ;
rdfs:comment "Serous membrane layer that lines to a body cavity." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:GO_0051031 a rdfs:Class ;
rdfs:label "tRNA transport" ;
rdfs:comment "The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0050658 .
obo:UBERON_0003123 a rdfs:Class ;
rdfs:label "pharyngeal arch artery 6" ;
rdfs:comment "The vessels formed within the sixth pair of branchial arches in embryogenesis." ;
rdfs:subClassOf obo:UBERON_0004363 .
obo:GO_1903847 a rdfs:Class ;
rdfs:label "regulation of aorta morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of aorta morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905651 .
obo:CHEBI_45064 a rdfs:Class ;
rdfs:label "phosphite(3-)" ;
rdfs:comment "A trivalent inorganic anion obtained by removal of all three protons from phosphorous acid." ;
rdfs:subClassOf obo:CHEBI_26045 , obo:CHEBI_79387 .
obo:PHIPO_0000049 a rdfs:Class ;
rdfs:label "increased number of sexual spores"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of sexual spores is increased." ;
rdfs:subClassOf obo:PHIPO_0000073 .
obo:PATO_0002006 a rdfs:Class ;
rdfs:label "2-D shape" ;
rdfs:comment "A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:GO_0001755 a rdfs:Class ;
rdfs:label "neural crest cell migration" ;
rdfs:comment "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0090497 .
obo:GO_2000700 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle cell myoblast differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation." ;
rdfs:subClassOf obo:GO_0045663 , obo:GO_0051891 , obo:GO_0065007 , obo:GO_2000690 .
obo:GO_0005902 a rdfs:Class ;
rdfs:label "microvillus" ;
rdfs:comment "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells." ;
rdfs:subClassOf obo:GO_0098858 .
obo:UBERON_0014283 a rdfs:Class ;
rdfs:label "piriform cortex layer 3" ;
rdfs:comment "Deepest of 3 cytoarchitecturally defined layers of the piriform cortex characterized by a moderately high density of pyramidal cells and large numbers of basal dendrites descending from pyramidal cells in layer 2." ;
rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0022303 .
obo:GO_1905633 a rdfs:Class ;
rdfs:label "establishment of protein localization to euchromatin" ;
rdfs:comment "The directed movement of a protein to a specific location in an euchromatin." ;
rdfs:subClassOf obo:GO_0045184 , obo:GO_0071169 , obo:GO_1905632 .
obo:CHEBI_7566 a rdfs:Class ;
rdfs:label "Nifurtimox" ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87230 .
obo:CL_0002240 a rdfs:Class ;
rdfs:label "marrow fibroblast" ;
rdfs:comment "A fibroblast in the bone marrow." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0010001 .
obo:GO_0031122 a rdfs:Class ;
rdfs:label "cytoplasmic microtubule organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." ;
rdfs:subClassOf obo:GO_0000226 , obo:GO_0016043 , obo:GO_0097435 .
obo:GO_1990239 a rdfs:Class ;
rdfs:label "steroid hormone binding" ;
rdfs:comment "Binding to a steroid hormone." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0005496 , obo:GO_0042562 .
obo:CHEBI_35341 a rdfs:Class ;
rdfs:label "steroid" ;
rdfs:comment "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." ;
rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_51958 .
obo:GO_0004888 a rdfs:Class ;
rdfs:label "transmembrane signaling receptor activity" ;
rdfs:comment "Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction." ;
rdfs:subClassOf obo:GO_0038023 .
obo:GO_0032252 a rdfs:Class ;
rdfs:label "secretory granule localization" ;
rdfs:comment "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051648 .
obo:GO_0031406 a rdfs:Class ;
rdfs:label "carboxylic acid binding" ;
rdfs:comment "Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0043168 , obo:GO_0043177 .
obo:PHIPO_0001160 a rdfs:Class ;
rdfs:label "abolished pathogen tissue to tissue migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally from tissue to tissue within the host organism is abolished (pathogen migration was present within the host and is now absent)." ;
rdfs:subClassOf obo:PHIPO_0001159 .
obo:GO_0050839 a rdfs:Class ;
rdfs:label "cell adhesion molecule binding" ;
rdfs:comment "Binding to a cell adhesion molecule." ;
rdfs:subClassOf obo:GO_0005515 .
obo:GO_0007017 a rdfs:Class ;
rdfs:label "microtubule-based process" ;
rdfs:comment "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." ;
rdfs:subClassOf obo:GO_0009987 .
obo:PHIPO_0000573 a rdfs:Class ;
rdfs:label "resistance to gentamycin C1"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to gentamycin C1. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000659 .
obo:CL_4301614 a rdfs:Class ;
rdfs:label "mature myelinating oligodendrocyte (Mmus)" ;
rdfs:comment "A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Anln (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1184 MOL NN_4." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4072003 , obo:CL_4300367 .
obo:UBERON_0001808 a rdfs:Class ;
rdfs:label "parasympathetic ganglion" ;
rdfs:comment "Ganglion containing neurons that receive innervation from parasympathetic neurons in the central nervous system and subserves parasympathetic functions through innervation of smooth muscle, cardiac muscle and glands." ;
rdfs:subClassOf obo:UBERON_0001805 , obo:UBERON_0010313 .
obo:GO_1904752 a rdfs:Class ;
rdfs:label "regulation of vascular associated smooth muscle cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration." ;
rdfs:subClassOf obo:GO_0014910 , obo:GO_0065007 .
obo:GO_0032594 a rdfs:Class ;
rdfs:label "protein transport within lipid bilayer" ;
rdfs:comment "The directed movement of a protein from one location to another within a lipid bilayer." ;
rdfs:subClassOf obo:GO_0006886 , obo:GO_0015031 , obo:GO_0061024 .
obo:CL_0002001 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-positive granulocyte monocyte progenitor" ;
rdfs:comment "A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative." ;
rdfs:subClassOf obo:CL_0000557 .
obo:CL_4301625 a rdfs:Class ;
rdfs:label "border associated macrophage (Mmus)" ;
rdfs:comment "A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Maf (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1195 BAM NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4042003 .
obo:PHIPO_0000040 a rdfs:Class ;
rdfs:label "abnormal mutualism"@en ;
rdfs:comment "A phenotype in which the balance of symbiotic mutualism has been disrupted compared to the normal interaction." ;
rdfs:subClassOf obo:PHIPO_0000038 .
obo:GO_0046903 a rdfs:Class ;
rdfs:label "secretion" ;
rdfs:comment "The controlled release of a substance by a cell or a tissue." ;
rdfs:subClassOf obo:GO_0006810 .
obo:GO_0005583 a rdfs:Class ;
rdfs:label "fibrillar collagen trimer" ;
rdfs:comment "Any triple helical collagen trimer that forms fibrils." ;
rdfs:subClassOf obo:GO_0005581 , obo:GO_0140392 .
obo:PATO_0000498 a rdfs:Class ;
rdfs:label "increased duration" ;
rdfs:comment "A duration quality of a process which is relatively high." ;
rdfs:subClassOf obo:PATO_0001309 , obo:PATO_0002304 .
obo:GO_0043021 a rdfs:Class ;
rdfs:label "ribonucleoprotein complex binding" ;
rdfs:comment "Binding to a complex of RNA and protein." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0044877 .
obo:GO_1903295 a rdfs:Class ;
rdfs:label "negative regulation of glutamate secretion, neurotransmission" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission." ;
rdfs:subClassOf obo:GO_0014050 , obo:GO_0046929 , obo:GO_0051967 , obo:GO_0065007 , obo:GO_1903294 .
obo:GO_0106216 a rdfs:Class ;
rdfs:label "positive regulation of vesicle fusion with Golgi apparatus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus." ;
rdfs:subClassOf obo:GO_0031340 , obo:GO_0065007 , obo:GO_0106214 .
obo:GO_0055009 a rdfs:Class ;
rdfs:label "atrial cardiac muscle tissue morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of cardiac atrium muscle is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0055008 .
obo:CHEBI_87114 a rdfs:Class ;
rdfs:label "antibiotic fungicide" ;
rdfs:comment "Any antibiotic antifungal agent that has been used as a fungicide." ;
rdfs:subClassOf obo:CHEBI_86478 .
obo:UBERON_0004177 a rdfs:Class ;
rdfs:label "hemopoietic organ" ;
rdfs:comment "Organ that is part of the hematopoietic system." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:CHEBI_74783 a rdfs:Class ;
rdfs:label "astringent" ;
rdfs:comment "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_1904145 a rdfs:Class ;
rdfs:label "negative regulation of meiotic cell cycle process involved in oocyte maturation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." ;
rdfs:subClassOf obo:GO_0010948 , obo:GO_0051447 , obo:GO_0065007 , obo:GO_1900194 , obo:GO_1903538 .
obo:PHIPO_0001041 a rdfs:Class ;
rdfs:label "obsolete increased level of a substance in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is higher than normal." .
obo:UBERON_0007300 a rdfs:Class ;
rdfs:label "pectoral appendage blood vessel" ;
rdfs:comment "A blood vessel that is part of a pectoral appendage." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0007301 .
obo:GO_0014038 a rdfs:Class ;
rdfs:label "regulation of Schwann cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of Schwann cell differentiation." ;
rdfs:subClassOf obo:GO_0045685 , obo:GO_0065007 .
obo:PHIPO_0000718 a rdfs:Class ;
rdfs:label "sensitive to polymyxin B1"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to polymyxin B1. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_28368 a rdfs:Class ;
rdfs:label "novobiocin" ;
rdfs:comment "A coumarin-derived antibiotic obtained from Streptomyces niveus." ;
rdfs:subClassOf obo:CHEBI_23003 , obo:CHEBI_25698 , obo:CHEBI_29347 , obo:CHEBI_33853 , obo:CHEBI_35313 , obo:CHEBI_37912 , obo:CHEBI_63367 .
obo:GO_0048705 a rdfs:Class ;
rdfs:label "skeletal system morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the skeleton are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:GO_0002580 a rdfs:Class ;
rdfs:label "regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." ;
rdfs:subClassOf obo:GO_0002577 , obo:GO_0065007 .
obo:PHIPO_0000937 a rdfs:Class ;
rdfs:label "asexual spore lysis present"@en ;
rdfs:comment "An single species phenotype in which an asexual spore lyses, i.e. the plasma membrane ruptures and cytoplasm is lost." ;
rdfs:subClassOf obo:PHIPO_0000936 .
obo:CHEBI_38445 a rdfs:Class ;
rdfs:label "chromenone" ;
rdfs:subClassOf obo:CHEBI_23232 .
obo:CHEBI_76042 a rdfs:Class ;
rdfs:label "aromatic amino-acid zwitterion" ;
rdfs:comment "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any aromatic amino-acid." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:GO_0021990 a rdfs:Class ;
rdfs:label "neural plate formation" ;
rdfs:comment "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." ;
rdfs:subClassOf obo:GO_0048646 .
obo:UBERON_0012324 a rdfs:Class ;
rdfs:label "transverse cervical artery" ;
rdfs:comment "The transverse cervical artery (transverse artery of neck, transversa colli artery) is a branch of the thyrocervical trunk, running at a higher level than the suprascapular artery." ;
rdfs:subClassOf obo:UBERON_0012320 .
obo:CL_4307132 a rdfs:Class ;
rdfs:label "microglial cell (Mmus)" ;
rdfs:comment "A microglial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C1qa (Mmus), Tmem119 (Mmus). It is distinguished from other Immune cells by expression of C1qa, Tmem119. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5312 Microglia NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000129 .
obo:CHEBI_26873 a rdfs:Class ;
rdfs:label "terpenoid" ;
rdfs:comment "Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group." ;
rdfs:subClassOf obo:CHEBI_24913 .
obo:CHEBI_33282 a rdfs:Class ;
rdfs:label "antibacterial agent" ;
rdfs:comment "A substance (or active part thereof) that kills or slows the growth of bacteria." ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:GO_1902761 a rdfs:Class ;
rdfs:label "positive regulation of chondrocyte development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chondrocyte development." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0032332 , obo:GO_0061181 , obo:GO_0065007 .
obo:CHEBI_64933 a rdfs:Class ;
rdfs:label "melanin synthesis inhibitor" ;
rdfs:comment "A depigmentation agent which inhibits the synthesis of melanin." ;
rdfs:subClassOf obo:CHEBI_59864 .
obo:CL_0002222 a rdfs:Class ;
rdfs:label "vertebrate lens cell" ;
rdfs:comment "A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0000306 .
obo:CL_1000376 a rdfs:Class ;
rdfs:label "Purkinje myocyte of interventricular septum" ;
rdfs:comment "A Purkinje myocyte that is part of the interventricular septum." ;
rdfs:subClassOf obo:CL_0002068 , obo:CL_2000022 .
obo:GO_0002037 a rdfs:Class ;
rdfs:label "negative regulation of L-glutamate import across plasma membrane" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell." ;
rdfs:subClassOf obo:GO_0002036 , obo:GO_0032891 , obo:GO_0034763 , obo:GO_0051956 , obo:GO_0065007 .
obo:UBERON_0012054 a rdfs:Class ;
rdfs:label "myocoele" ;
rdfs:comment "The cavity within a myotome." ;
rdfs:subClassOf obo:UBERON_0002553 .
obo:GO_1900143 a rdfs:Class ;
rdfs:label "positive regulation of oligodendrocyte apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process." ;
rdfs:subClassOf obo:GO_0034352 , obo:GO_0065007 , obo:GO_1900141 .
obo:GO_0022032 a rdfs:Class ;
rdfs:label "telencephalon oligodendrocyte cell migration" ;
rdfs:comment "The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0022030 .
obo:CHEBI_36244 a rdfs:Class ;
rdfs:label "dicarboxylic acid monoester" ;
rdfs:comment "A monoester of a dicarboxylic acid." ;
rdfs:subClassOf obo:CHEBI_131927 , obo:CHEBI_33308 , obo:CHEBI_33575 .
obo:UBERON_0002351 a rdfs:Class ;
rdfs:label "sinoatrial node" ;
rdfs:comment "The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]." ;
rdfs:subClassOf obo:UBERON_0003379 , obo:UBERON_0010131 .
obo:UBERON_0005173 a rdfs:Class ;
rdfs:label "abdominal segment element" ;
rdfs:comment "An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region." ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0005177 .
obo:GO_0021706 a rdfs:Class ;
rdfs:label "locus ceruleus maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:PHIPO_0000193 a rdfs:Class ;
rdfs:label "obsolete increased pathogen host interaction DNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is increased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:GO_0001707 a rdfs:Class ;
rdfs:label "mesoderm formation" ;
rdfs:comment "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0001704 , obo:GO_0048646 .
obo:GO_0044111 a rdfs:Class ;
rdfs:label "formation of structure involved in a symbiotic process" ;
rdfs:comment "The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0044419 .
obo:GO_0043200 a rdfs:Class ;
rdfs:label "response to amino acid" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." ;
rdfs:subClassOf obo:GO_0001101 , obo:GO_0050896 .
obo:PR_000001813 a rdfs:Class ;
rdfs:label "adhesion G protein-coupled receptor E1" ;
rdfs:comment "An adhesion G-protein coupled receptor that is a translation product of the human ADGRE1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001087 .
obo:UBERON_0034728 a rdfs:Class ;
rdfs:label "autonomic nerve" ;
rdfs:comment "The autonomic nerve is a small nerve which carries postganglionic sympathetic and parasympathetic neurons from the zygomaticotemporal nerve; a branch of the maxillary nerve, to the lacrimal nerve; a branch of the ophthalmic nerve. These neurons derive from the superior cervical ganglion and the pterygopalatine ganglion respectively. They will travel to the lacrimal gland via the lacrimal nerve. Parasympathetic will induce lacrimation and vice versa." ;
rdfs:subClassOf obo:UBERON_0011779 .
obo:UBERON_0002338 a rdfs:Class ;
rdfs:label "lamina propria of bronchus" ;
rdfs:comment "A lamina propria that is part of a bronchus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000030 , obo:UBERON_0000031 .
obo:UBERON_0003113 a rdfs:Class ;
rdfs:label "dermatocranium" ;
rdfs:comment "Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]." ;
rdfs:subClassOf obo:UBERON_0011159 .
obo:GO_0021702 a rdfs:Class ;
rdfs:label "cerebellar Purkinje cell differentiation" ;
rdfs:comment "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem." ;
rdfs:subClassOf obo:GO_0021533 , obo:GO_0021953 , obo:GO_0030154 , obo:GO_0097154 .
obo:UBERON_0000332 a rdfs:Class ;
rdfs:label "yellow bone marrow" ;
rdfs:comment "Bone marrow in which the fat cells predominate in the meshes of the reticular network." ;
rdfs:subClassOf obo:UBERON_0002371 .
obo:GO_0009508 a rdfs:Class ;
rdfs:label "plastid chromosome" ;
rdfs:comment "A circular DNA molecule containing plastid encoded genes." ;
rdfs:subClassOf obo:GO_0005694 .
obo:UBERON_0002263 a rdfs:Class ;
rdfs:label "lentiform nucleus" ;
rdfs:comment "The lentiform nucleus or lenticular nucleus comprises the putamen and the globus pallidus within the basal ganglia. It is a large, cone-shaped mass of gray matter just lateral to the internal capsule. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0009663 .
obo:GO_0009668 a rdfs:Class ;
rdfs:label "plastid membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0061024 .
obo:NCBITaxon_32523 a rdfs:Class ;
rdfs:label "Tetrapoda" ;
rdfs:subClassOf obo:NCBITaxon_1338369 .
obo:UBERON_0000077 a rdfs:Class ;
rdfs:label "mixed endoderm/mesoderm-derived structure" ;
rdfs:comment "An anatomical structure that develops from the endoderm and the mesoderm." ;
rdfs:subClassOf obo:UBERON_0000061 , obo:UBERON_0004119 , obo:UBERON_0004120 .
obo:UBERON_0001891 a rdfs:Class ;
rdfs:label "midbrain" ;
rdfs:comment "The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]." ;
rdfs:subClassOf obo:UBERON_0002616 , obo:UBERON_0004121 , obo:UBERON_0010314 .
obo:CL_1000361 a rdfs:Class ;
rdfs:label "transitional myocyte of interatrial septum" ;
rdfs:comment "A transitional myocyte that is part of the interatrial septum." ;
rdfs:subClassOf obo:CL_0002073 , obo:CL_2000022 .
obo:CHEBI_25478 a rdfs:Class ;
rdfs:label "naphthalenesulfonate" ;
rdfs:subClassOf obo:CHEBI_22713 .
obo:CL_4307093 a rdfs:Class ;
rdfs:label "COP NN_1 9130019P16Rik committed oligodendrocyte precursor (Mmus)" ;
rdfs:comment "A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Gp1bb (Mmus), Pdzd2 (Mmus), Plekhg1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Rgcc, 9130019P16Rik. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5273 COP NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301611 .
obo:GO_0034248 a rdfs:Class ;
rdfs:label "regulation of amide metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_0051875 a rdfs:Class ;
rdfs:label "pigment granule localization" ;
rdfs:comment "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051648 .
obo:PHIPO_0001302 a rdfs:Class ;
rdfs:label "resistance to osmotic stress"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to an osmotic stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die)." ;
rdfs:subClassOf obo:PHIPO_0001096 .
obo:GO_0002069 a rdfs:Class ;
rdfs:label "columnar/cuboidal epithelial cell maturation" ;
rdfs:comment "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ;
rdfs:subClassOf obo:GO_0002070 , obo:GO_0021700 .
obo:GO_0004518 a rdfs:Class ;
rdfs:label "nuclease activity" ;
rdfs:comment "Catalysis of the cleavage of ester linkages within nucleic acids." ;
rdfs:subClassOf obo:GO_0140640 .
obo:CL_0002673 a rdfs:Class ;
rdfs:label "tongue muscle cell" ;
rdfs:comment "A skeletal muscle cell that is part of the tongue." ;
rdfs:subClassOf obo:CL_0008002 .
obo:GO_0019835 a rdfs:Class ;
rdfs:label "cytolysis" ;
rdfs:comment "The rupture of cell membranes and the loss of cytoplasm." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0034436 a rdfs:Class ;
rdfs:label "glycoprotein transport" ;
rdfs:comment "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015031 , obo:GO_1901264 .
obo:GO_1901700 a rdfs:Class ;
rdfs:label "response to oxygen-containing compound" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." ;
rdfs:subClassOf obo:GO_0042221 , obo:GO_0050896 .
obo:GO_0042325 a rdfs:Class ;
rdfs:label "regulation of phosphorylation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_1904778 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to cell cortex" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904377 , obo:GO_1904776 .
obo:CL_4023068 a rdfs:Class ;
rdfs:label "thalamic excitatory neuron" ;
rdfs:comment "An excitatory neuron that has its soma located in the thalamic complex. This neuron type can be involved in a series of circuits related to sensory integration, motor integration, pain processing, social behaviour and reward response." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_0000679 , obo:CL_0012001 .
obo:GO_0034655 a rdfs:Class ;
rdfs:label "nucleobase-containing compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0006139 , obo:GO_0009056 .
obo:UBERON_0001915 a rdfs:Class ;
rdfs:label "endothelium of capillary" ;
rdfs:comment "An endothelium that is part of a capillary [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0008339 .
obo:PHIPO_0001266 a rdfs:Class ;
rdfs:label "increased host hemorrhage with pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the host bleeding during pathogen infection occurs to a greater extent than normal (MP:0001914 hemorrhage)." ;
rdfs:subClassOf obo:PHIPO_0001265 .
obo:CL_4030043 a rdfs:Class ;
rdfs:label "matrix D1 medium spiny neuron" ;
rdfs:comment "A DRD1-expressing medium spiny neuron that is part of a matrix compartment of dorsal striatum." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_4023026 .
obo:CL_4307052 a rdfs:Class ;
rdfs:label "Astro-OLF NN_1 Stk32a astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Prss23 (Mmus), Stk32a (Mmus). It is distinguished from other Astro-OLF NN_1 cells by expression of Stk32a. These cells are located in the Olfactory areas, brain , in or close to the regions: olfactory nerve layer of main olfactory bulb, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5232 Astro-OLF NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301596 .
obo:GO_0022898 a rdfs:Class ;
rdfs:label "regulation of transmembrane transporter activity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of transmembrane transporter activity." ;
rdfs:subClassOf obo:GO_0034762 , obo:GO_0065007 , obo:GO_0065009 .
obo:PHIPO_0001031 a rdfs:Class ;
rdfs:label "decreased cellular toxin level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of toxin measured in a cell is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001030 , obo:PHIPO_0001035 .
obo:GO_0046943 a rdfs:Class ;
rdfs:label "carboxylic acid transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." ;
rdfs:subClassOf obo:GO_0022857 .
obo:GO_0061551 a rdfs:Class ;
rdfs:label "trigeminal ganglion development" ;
rdfs:comment "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0061550 .
obo:GO_0007009 a rdfs:Class ;
rdfs:label "plasma membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0061024 .
obo:GO_0051460 a rdfs:Class ;
rdfs:label "negative regulation of corticotropin secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell." ;
rdfs:subClassOf obo:GO_0051241 , obo:GO_0051459 , obo:GO_0065007 , obo:GO_0090278 .
obo:GO_0050906 a rdfs:Class ;
rdfs:label "detection of stimulus involved in sensory perception" ;
rdfs:comment "The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0051606 .
obo:PHIPO_0000742 a rdfs:Class ;
rdfs:label "sensitive to triclosan"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to triclosan. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0070133 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial translational initiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." ;
rdfs:subClassOf obo:GO_0045947 , obo:GO_0065007 , obo:GO_0070132 .
obo:GO_0008104 a rdfs:Class ;
rdfs:label "protein localization" ;
rdfs:comment "Any process in which a protein is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0070727 .
obo:GO_0071944 a rdfs:Class ;
rdfs:label "cell periphery" ;
rdfs:comment "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0060323 a rdfs:Class ;
rdfs:label "head morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CL_0000542 a rdfs:Class ;
rdfs:label "lymphocyte" ;
rdfs:comment "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." ;
rdfs:subClassOf obo:CL_0000738 , obo:CL_0000842 .
obo:GO_0008354 a rdfs:Class ;
rdfs:label "primordial germ cell migration" ;
rdfs:comment "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." ;
rdfs:subClassOf obo:GO_0016477 .
obo:GO_0002449 a rdfs:Class ;
rdfs:label "lymphocyte mediated immunity" ;
rdfs:comment "Any process involved in the carrying out of an immune response by a lymphocyte." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0002443 .
obo:GO_0000803 a rdfs:Class ;
rdfs:label "sex chromosome" ;
rdfs:comment "A chromosome involved in sex determination." ;
rdfs:subClassOf obo:GO_0005694 .
obo:GO_0047496 a rdfs:Class ;
rdfs:label "vesicle transport along microtubule" ;
rdfs:comment "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0072384 , obo:GO_0099518 .
obo:PHIPO_0000696 a rdfs:Class ;
rdfs:label "resistance to copper sulphate"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to copper sulphate. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000187 a rdfs:Class ;
rdfs:label "obsolete abolished pathogen host interaction DNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:GO_0045144 a rdfs:Class ;
rdfs:label "meiotic sister chromatid segregation" ;
rdfs:comment "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0000819 , obo:GO_0045132 , obo:GO_0070192 .
obo:UBERON_0005156 a rdfs:Class ;
rdfs:label "reproductive structure" ;
rdfs:comment "Any anatomical structure that is part of the reproductive system." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:UBERON_0003828 a rdfs:Class ;
rdfs:label "abdominal segment bone" ;
rdfs:comment "A bone that is part of an abdominal segment of trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0003463 , obo:UBERON_0005173 .
obo:UBERON_0002481 a rdfs:Class ;
rdfs:label "bone tissue" ;
rdfs:comment "Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts." ;
rdfs:subClassOf obo:UBERON_0004755 .
obo:CHEBI_50902 a rdfs:Class ;
rdfs:label "genotoxin" ;
rdfs:comment "A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:GO_0002573 a rdfs:Class ;
rdfs:label "myeloid leukocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage." ;
rdfs:subClassOf obo:GO_0002521 , obo:GO_0030099 , obo:GO_0030154 .
obo:GO_0090454 a rdfs:Class ;
rdfs:label "glutamate transmembrane import into vacuole" ;
rdfs:comment "The directed movement of glutamate into the vacuole across the vacuolar membrane." ;
rdfs:subClassOf obo:GO_0006835 , obo:GO_0015800 , obo:GO_0032975 , obo:GO_0071705 , obo:GO_1905039 .
obo:GO_0030312 a rdfs:Class ;
rdfs:label "external encapsulating structure" ;
rdfs:comment "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0070447 a rdfs:Class ;
rdfs:label "positive regulation of oligodendrocyte progenitor proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation." ;
rdfs:subClassOf obo:GO_0014015 , obo:GO_0065007 , obo:GO_0070445 , obo:GO_2000179 .
obo:GO_0035261 a rdfs:Class ;
rdfs:label "external genitalia morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0035112 .
obo:CHEBI_37630 a rdfs:Class ;
rdfs:label "alpha-L-glucose" ;
rdfs:comment "A L-glucopyranose with an α-configuration at the anomeric position." ;
rdfs:subClassOf obo:CHEBI_37627 .
obo:CHEBI_25805 a rdfs:Class ;
rdfs:label "oxygen atom" ;
rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33303 .
obo:UBERON_0002036 a rdfs:Class ;
rdfs:label "striated muscle tissue" ;
rdfs:comment "Muscle tissue that contains fibers that are divided by transverse bands into striations." ;
rdfs:subClassOf obo:UBERON_0002385 .
obo:GO_0030324 a rdfs:Class ;
rdfs:label "lung development" ;
rdfs:comment "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:GO_0051683 a rdfs:Class ;
rdfs:label "establishment of Golgi localization" ;
rdfs:comment "The directed movement of the Golgi to a specific location." ;
rdfs:subClassOf obo:GO_0051234 , obo:GO_0051645 , obo:GO_0051649 , obo:GO_0051656 .
obo:CL_1000466 a rdfs:Class ;
rdfs:label "chromaffin cell of right ovary" ;
rdfs:comment "A chromaffin cell that is part of the right ovary." ;
rdfs:subClassOf obo:CL_0000166 , obo:CL_1000465 .
obo:UBERON_0003709 a rdfs:Class ;
rdfs:label "circle of Willis" ;
rdfs:comment "A circle of arteries that supply blood to the brain. The Circle of Willis comprises the following arteries: Anterior cerebral artery (left and right); Anterior communicating artery; Internal carotid artery (left and right); Posterior cerebral artery (left and right); Posterior communicating artery (left and right).The basilar artery and middle cerebral arteries, supplying the brain, are also considered part of the circle." ;
rdfs:subClassOf obo:UBERON_0004573 .
obo:PHIPO_0000334 a rdfs:Class ;
rdfs:label "abnormal pathogen cell to cell migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000333 .
obo:CHEBI_65076 a rdfs:Class ;
rdfs:label "neamine(4+)" ;
rdfs:comment "An organic cation obtained by protonation of the four free amino groups of neamine; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_0009657 a rdfs:Class ;
rdfs:label "plastid organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0016043 .
obo:CHEBI_33485 a rdfs:Class ;
rdfs:label "chalcogen oxoanion" ;
rdfs:subClassOf obo:CHEBI_35406 .
obo:GO_0030473 a rdfs:Class ;
rdfs:label "nuclear migration along microtubule" ;
rdfs:comment "The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0007097 , obo:GO_0072384 .
obo:PHIPO_0000300 a rdfs:Class ;
rdfs:label "abnormal dissemination of asexual spore"@en ;
rdfs:comment "A single species phenotype where the dispersal of asexual spores is abnormal (FAO:0000023)." ;
rdfs:subClassOf obo:PHIPO_0000043 .
obo:PHIPO_0000690 a rdfs:Class ;
rdfs:label "resistance to novobiocin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to novobiocin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0002663 a rdfs:Class ;
rdfs:label "septal nuclear complex" ;
rdfs:comment "Collection of nerve cells in the medial forebrain lying generally in front of the anterior commissure (Maryann Martone)." ;
rdfs:subClassOf obo:UBERON_0005401 , obo:UBERON_0007245 .
obo:UBERON_0009676 a rdfs:Class ;
rdfs:label "early telencephalic vesicle" ;
rdfs:subClassOf obo:UBERON_0013150 .
obo:GO_1905564 a rdfs:Class ;
rdfs:label "positive regulation of vascular endothelial cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation." ;
rdfs:subClassOf obo:GO_0001938 , obo:GO_0065007 , obo:GO_1905562 .
obo:PHIPO_0001212 a rdfs:Class ;
rdfs:label "decreased hyphal growth"@en ;
rdfs:comment "An individual organism growth phenotype in which the growth of hyphae is decreased." ;
rdfs:subClassOf obo:PHIPO_0001215 .
obo:CHEBI_33710 a rdfs:Class ;
rdfs:label "alpha-amino-acid residue" ;
rdfs:comment "An amino-acid residue derived from an alpha-amino acid." ;
rdfs:subClassOf obo:CHEBI_33708 .
obo:GO_0007213 a rdfs:Class ;
rdfs:label "G protein-coupled acetylcholine receptor signaling pathway" ;
rdfs:comment "A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription." ;
rdfs:subClassOf obo:GO_0007165 , obo:GO_0007186 , obo:GO_0095500 .
obo:GO_0046827 a rdfs:Class ;
rdfs:label "positive regulation of protein export from nucleus" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0046824 , obo:GO_0046825 , obo:GO_0065007 , obo:GO_0090316 .
obo:CHEBI_35821 a rdfs:Class ;
rdfs:label "anticholesteremic drug" ;
rdfs:comment "A substance used to lower plasma cholesterol levels." ;
rdfs:subClassOf obo:CHEBI_35679 .
obo:CL_0002657 a rdfs:Class ;
rdfs:label "glandular cell of esophagus" ;
rdfs:comment "A glandular epithelial cell of the esophagus." ;
rdfs:subClassOf obo:CL_0000150 , obo:CL_0002252 .
obo:UBERON_3000972 a rdfs:Class ;
rdfs:label "head external integument structure" ;
rdfs:comment "Dermal, epidermal, glandular and pigment structures of the external head integument." ;
rdfs:subClassOf obo:UBERON_3000961 .
obo:UBERON_0003041 a rdfs:Class ;
rdfs:label "trigeminal nerve fibers" ;
rdfs:comment "A nerve fiber that is part of a trigeminal nerve." ;
rdfs:subClassOf obo:UBERON_0006134 .
obo:CL_0000225 a rdfs:Class ;
rdfs:label "anucleate cell" ;
rdfs:comment "A cell that lacks a nucleus." ;
rdfs:subClassOf obo:CL_0000000 .
obo:PATO_0001690 a rdfs:Class ;
rdfs:label "contractile" ;
rdfs:comment "A contractility quality inhering in a bearer by virtue of the bearer's ability of contracting or being contracted." ;
rdfs:subClassOf obo:PATO_0001579 .
obo:GO_2000178 a rdfs:Class ;
rdfs:label "negative regulation of neural precursor cell proliferation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0065007 , obo:GO_2000177 .
obo:PHIPO_0000720 a rdfs:Class ;
rdfs:label "sensitive to brefeldin A"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to brefeldin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0070346 a rdfs:Class ;
rdfs:label "positive regulation of fat cell proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of fat cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0065007 , obo:GO_0070344 .
obo:CL_4307041 a rdfs:Class ;
rdfs:label "Astro-TE NN_1 Jph4 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Sptbn2 (Mmus), Alpk1 (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Jph4, Alpk1. It is glutamatergic (inferred from expression of Aldh1a1, Slc17a7). These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5221 Astro-TE NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000151 , obo:CL_4301591 .
obo:GO_0007281 a rdfs:Class ;
rdfs:label "germ cell development" ;
rdfs:comment "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0022412 , obo:GO_0032502 , obo:GO_0048468 .
obo:CHEBI_23636 a rdfs:Class ;
rdfs:label "deoxyribonucleoside" ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:CHEBI_22718 a rdfs:Class ;
rdfs:label "benzoates" ;
rdfs:comment "A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid." ;
rdfs:subClassOf obo:CHEBI_35757 , obo:CHEBI_91007 .
obo:UBERON_0005732 a rdfs:Class ;
rdfs:label "paired limb/fin field" ;
rdfs:comment "A ring of cells capable of forming a limb or paired fin[Gilbert,modified]." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005291 , obo:UBERON_0007688 .
obo:PHIPO_0001403 a rdfs:Class ;
rdfs:label "sensitive to mandipropamid" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to mandipropamid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PATO_0002005 a rdfs:Class ;
rdfs:label "concavity" ;
rdfs:comment "Surface shape that refers to the inward or outward curvature of the surface." ;
rdfs:subClassOf obo:PATO_0000052 .
obo:CHEBI_27594 a rdfs:Class ;
rdfs:label "carbon atom" ;
rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33306 , obo:CHEBI_50860 .
obo:GO_0050931 a rdfs:Class ;
rdfs:label "pigment cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0051402 a rdfs:Class ;
rdfs:label "neuron apoptotic process" ;
rdfs:comment "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." ;
rdfs:subClassOf obo:GO_0006915 .
obo:GO_0140143 a rdfs:Class ;
rdfs:label "collagenous component of basement membrane" ;
rdfs:comment "Collagenous component of basement membrane ECMs, including collagen IV and other types of collagen specifically expressed in basement membrane." ;
rdfs:subClassOf obo:GO_0030312 .
obo:CHEBI_3992 a rdfs:Class ;
rdfs:label "cyclic ketone" ;
rdfs:subClassOf obo:CHEBI_17087 .
obo:GO_0010819 a rdfs:Class ;
rdfs:label "regulation of T cell chemotaxis" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901623 , obo:GO_2000404 .
obo:GO_1902414 a rdfs:Class ;
rdfs:label "protein localization to cell junction" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a cell junction." ;
rdfs:subClassOf obo:GO_0008104 .
obo:CHEBI_76907 a rdfs:Class ;
rdfs:label "EC 4.2.1.* (hydro-lyases) inhibitor" ;
rdfs:comment "An EC 4.2.* (C‒O lyase) inhibitor that interferes with the action of any hydro-lyase (EC 4.2.1.*)." ;
rdfs:subClassOf obo:CHEBI_76712 .
obo:PHIPO_0000039 a rdfs:Class ;
rdfs:label "normal mutualism"@en ;
rdfs:comment "A phenotype in which the interaction is the same as the wild-type, no asymptomatic colonisation or disease formation symptoms are visible." ;
rdfs:subClassOf obo:PHIPO_0000038 .
obo:PHIPO_0000437 a rdfs:Class ;
rdfs:label "increased catalytic activity"@en ;
rdfs:comment "A single species molecular function phenotype in which the observed rate of a specified catalytic activity is increased." ;
rdfs:subClassOf obo:PHIPO_0000434 .
obo:PHIPO_0001223 a rdfs:Class ;
rdfs:label "normal organism morphology"@en ;
rdfs:comment "A single species phenotype where the morphology of an organism is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001220 .
obo:UBERON_0011775 a rdfs:Class ;
rdfs:label "vagus nerve nucleus" ;
rdfs:comment "A cranial nerve nucleus that is associated with a vagus nerve." ;
rdfs:subClassOf obo:UBERON_0000126 , obo:UBERON_0009662 .
obo:UBERON_0002477 a rdfs:Class ;
rdfs:label "medial globus pallidus" ;
rdfs:comment "The more medial segment of the globus pallidus." ;
rdfs:subClassOf obo:UBERON_0005401 .
obo:GO_0001820 a rdfs:Class ;
rdfs:label "serotonin secretion" ;
rdfs:comment "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesized in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells." ;
rdfs:subClassOf obo:GO_0015850 , obo:GO_0023061 , obo:GO_0046903 , obo:GO_0071705 .
obo:UBERON_8480025 a rdfs:Class ;
rdfs:label "skin of clavicle region" ;
rdfs:comment "A zone of skin that is above the clavicle zone in the pectoral girdle region." ;
rdfs:subClassOf obo:UBERON_0000014 .
obo:GO_1903181 a rdfs:Class ;
rdfs:label "positive regulation of dopamine biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0045964 , obo:GO_0065007 , obo:GO_1903179 .
obo:GO_0010665 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle cell apoptotic process" ;
rdfs:comment "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." ;
rdfs:subClassOf obo:GO_0010662 , obo:GO_0065007 .
obo:CHEBI_7809 a rdfs:Class ;
rdfs:label "oxacillin" ;
rdfs:comment "A penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6β." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_17334 .
obo:UBERON_0008196 a rdfs:Class ;
rdfs:label "muscle of pectoral girdle" ;
rdfs:comment "Any muscle organ that is part of a pectoral girdle region." ;
rdfs:subClassOf obo:UBERON_0010891 , obo:UBERON_0014892 .
obo:CL_0000325 a rdfs:Class ;
rdfs:label "stuff accumulating cell" ;
rdfs:comment "A cell that is specialised to accumulate a particular substance(s)." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0055107 a rdfs:Class ;
rdfs:label "Golgi to secretory granule transport" ;
rdfs:comment "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex." ;
rdfs:subClassOf obo:GO_0010496 , obo:GO_0046907 .
obo:CHEBI_35842 a rdfs:Class ;
rdfs:label "antirheumatic drug" ;
rdfs:comment "A drug used to treat rheumatoid arthritis." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:PHIPO_0000135 a rdfs:Class ;
rdfs:label "abolished protein-protein interaction"@en ;
rdfs:comment "A single species molecular function phenotype in which the binding of one protein to another does not occur. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000133 .
obo:GO_1904397 a rdfs:Class ;
rdfs:label "negative regulation of neuromuscular junction development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904396 , obo:GO_1905809 .
obo:UBERON_0011120 a rdfs:Class ;
rdfs:label "laryngeal joint" ;
rdfs:comment "A skeletal joint that connects a laryngeal cartilage." ;
rdfs:subClassOf obo:UBERON_0000982 , obo:UBERON_0002217 .
obo:GO_0030098 a rdfs:Class ;
rdfs:label "lymphocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0046649 , obo:GO_1903131 .
obo:CHEBI_76733 a rdfs:Class ;
rdfs:label "EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on NADH or NADPH (EC 1.6.*.*)." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:GO_0031968 a rdfs:Class ;
rdfs:label "organelle outer membrane" ;
rdfs:comment "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0019867 , obo:GO_0098588 .
obo:CL_0001026 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-positive common myeloid progenitor" ;
rdfs:comment "A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative." ;
rdfs:subClassOf obo:CL_0000995 , obo:CL_0001059 .
obo:UBERON_0016565 a rdfs:Class ;
rdfs:label "cerebral blood vessel" ;
rdfs:comment "A blood vessel that is part of a cerebellum." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003499 .
obo:GO_1905864 a rdfs:Class ;
rdfs:label "regulation of Atg1/ULK1 kinase complex assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0065007 .
obo:PHIPO_0001442 a rdfs:Class ;
rdfs:label "abnormal biological process phenotype"@en ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:PHIPO_0000882 a rdfs:Class ;
rdfs:label "sensitive to tetracycline"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tetracycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0002521 a rdfs:Class ;
rdfs:label "leukocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0051258 a rdfs:Class ;
rdfs:label "protein polymerization" ;
rdfs:comment "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." ;
rdfs:subClassOf obo:GO_0065003 .
obo:GO_0001101 a rdfs:Class ;
rdfs:label "response to acid chemical" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." ;
rdfs:subClassOf obo:GO_0042221 .
obo:UBERON_0002288 a rdfs:Class ;
rdfs:label "choroid plexus of third ventricle" ;
rdfs:comment "Part of choroid plexus contained in the third ventricle." ;
rdfs:subClassOf obo:UBERON_0001886 .
obo:GO_0043030 a rdfs:Class ;
rdfs:label "regulation of macrophage activation" ;
rdfs:comment "Any process that modulates the frequency or rate of macrophage activation." ;
rdfs:subClassOf obo:GO_0002694 , obo:GO_0065007 .
obo:GO_0043436 a rdfs:Class ;
rdfs:label "oxoacid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ;
rdfs:subClassOf obo:GO_0006082 , obo:GO_0008152 .
obo:GO_0032278 a rdfs:Class ;
rdfs:label "positive regulation of gonadotropin secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin." ;
rdfs:subClassOf obo:GO_0032276 , obo:GO_0046887 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_1990917 a rdfs:Class ;
rdfs:label "ooplasm" ;
rdfs:comment "The cytoplasm of an ovum." ;
rdfs:subClassOf obo:GO_0005737 .
obo:CL_0002139 a rdfs:Class ;
rdfs:label "endothelial cell of vascular tree" ;
rdfs:comment "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." ;
rdfs:subClassOf obo:CL_0000115 .
obo:CHEBI_83039 a rdfs:Class ;
rdfs:label "crustacean metabolite" ;
rdfs:comment "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." ;
rdfs:subClassOf obo:CHEBI_75767 .
obo:GO_0099512 a rdfs:Class ;
rdfs:label "supramolecular fiber" ;
rdfs:comment "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." ;
rdfs:subClassOf obo:GO_0099080 , obo:GO_0099081 .
obo:GO_0060920 a rdfs:Class ;
rdfs:label "cardiac pacemaker cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0055007 .
obo:PR_000001018 a rdfs:Class ;
rdfs:label "CD3 subunit with immunoglobulin domain" ;
rdfs:comment "A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PHIPO_0001100 a rdfs:Class ;
rdfs:label "increased level of pathogen RNA within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen RNA usually present during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001267 .
obo:UBERON_0005666 a rdfs:Class ;
rdfs:label "4th arch endoderm" ;
rdfs:comment "An endoderm that is part of a pharyngeal arch 4." ;
rdfs:subClassOf obo:UBERON_0000925 .
obo:PHIPO_0001197 a rdfs:Class ;
rdfs:label "level of pathogen produced substance within host phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, which affects the level of a pathogen produced substance during host infection." ;
rdfs:subClassOf obo:PHIPO_0000510 .
obo:CHEBI_16385 a rdfs:Class ;
rdfs:label "organic sulfide" ;
rdfs:comment "Compounds having the structure RSR (R ≠ H). Such compounds were once called thioethers." ;
rdfs:subClassOf obo:CHEBI_26822 , obo:CHEBI_33261 .
obo:CL_4023029 a rdfs:Class ;
rdfs:label "indirect pathway medium spiny neuron" ;
rdfs:comment "A GABAergic medium spiny neuron located in the striatum that gives rise to the indirect basal ganglia pathway. It projects to the GPe, where its axon typically ramifies in two regions but does not extend beyond this nucleus (Gerfen et al., 2022). It selectively expresses the D2 dopamine receptor (DRD2), which couples to inhibitory G-proteins (Gi/o) to decrease cAMP and suppress PKA-mediated signaling (Gerfen et al., 2022). Morphologically, this cell displays fewer and shorter dendrites than the MSN-D1 and receives fewer glutamatergic inputs, yet it exhibits significantly higher intrinsic excitability (Gertler et al., 2022). Functionally, activation of this cell suppresses competing or alternative motor actions by inhibiting GPe neurons, leading through STN and other GPe circuits to increased GPi/SNr output and stronger inhibition of thalamic and brainstem targets (Mink, 1996; Tecuapetla et al., 2016)." ;
rdfs:subClassOf obo:CL_1001474 .
obo:CHEBI_87132 a rdfs:Class ;
rdfs:label "morpholine antifungal agent" ;
rdfs:comment "A member of the class of morpholines that has significant antifungal properties." ;
rdfs:subClassOf obo:CHEBI_38785 .
obo:PHIPO_0001081 a rdfs:Class ;
rdfs:label "absence of melanin accumulation in pathogen asexual spore within host"@en ;
rdfs:comment "A pathogen host interaction, in which the accumulation of melanin within a pathogen asexual spore, usually present during infection, is absent." ;
rdfs:subClassOf obo:PHIPO_0001080 .
obo:CL_0000095 a rdfs:Class ;
rdfs:label "neuron associated cell" ;
rdfs:subClassOf obo:CL_0002319 .
obo:PHIPO_0000104 a rdfs:Class ;
rdfs:label "increased size of penetration structure"@en ;
rdfs:comment "A single species pathogen growth phenotype in which the size of pathogen penetration stuctures are increased when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000032 .
obo:UBERON_0003372 a rdfs:Class ;
rdfs:label "pectoral appendage bud ectoderm" ;
rdfs:comment "An unilaminar epithelium that surrounds a pectoral appendage bud." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0005291 .
obo:UBERON_0003306 a rdfs:Class ;
rdfs:label "floor plate of neural tube" ;
rdfs:comment "A floor plate that is part of a neural tube [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000481 .
obo:UBERON_0007195 a rdfs:Class ;
rdfs:label "stroma of bone marrow" ;
rdfs:comment "The stroma of the bone marrow is all tissue not directly involved in the primary function of hematopoiesis. The yellow bone marrow belongs here, and makes the majority of the bone marrow stroma, in addition to stromal cells located in the red bone marrow. Yellow bone marrow is found in the Medullary cavity. Still, the stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. For instance, they generate colony stimulating factors, affecting hematopoiesis." ;
rdfs:subClassOf obo:UBERON_0003891 .
obo:GO_0035249 a rdfs:Class ;
rdfs:label "synaptic transmission, glutamatergic" ;
rdfs:comment "The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ;
rdfs:subClassOf obo:GO_0007268 .
obo:GO_1905223 a rdfs:Class ;
rdfs:label "epicardium morphogenesis" ;
rdfs:comment "The developmental process by which an epicardium is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PHIPO_0000528 a rdfs:Class ;
rdfs:label "resistance to prochloraz"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to prochloraz. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1904934 a rdfs:Class ;
rdfs:label "negative regulation of cell proliferation in midbrain" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904933 , obo:GO_2000178 .
obo:CHEBI_233202 a rdfs:Class ;
rdfs:label "paromomycin(5+)" ;
rdfs:subClassOf obo:CHEBI_35274 .
obo:GO_0030246 a rdfs:Class ;
rdfs:label "carbohydrate binding" ;
rdfs:comment "Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates." ;
rdfs:subClassOf obo:GO_0005488 .
obo:GO_0070887 a rdfs:Class ;
rdfs:label "cellular response to chemical stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ;
rdfs:subClassOf obo:GO_0042221 , obo:GO_0051716 .
obo:GO_1902106 a rdfs:Class ;
rdfs:label "negative regulation of leukocyte differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902105 , obo:GO_1903707 .
obo:PHIPO_0000426 a rdfs:Class ;
rdfs:label "obsolete presence of pathogen chitinase binding to pathogen chitin fragments within host interaction" ;
rdfs:comment "A molecular function phenotype in which the binding of pathogen chitinase to pathogen chitin fragments generated within a host interaction is present." .
obo:CHEBI_50346 a rdfs:Class ;
rdfs:label "emamectins" ;
rdfs:subClassOf obo:CHEBI_25106 .
obo:UBERON_0003617 a rdfs:Class ;
rdfs:label "trachea elastic tissue" ;
rdfs:comment "An elastic tissue that is part of a trachea [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002521 , obo:UBERON_0003571 , obo:UBERON_0003611 .
obo:GO_0055118 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle contraction" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction." ;
rdfs:subClassOf obo:GO_0045822 , obo:GO_0045988 , obo:GO_0055117 , obo:GO_0065007 .
obo:CHEBI_8653 a rdfs:Class ;
rdfs:label "pyocyanine" ;
rdfs:comment "An iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group. An antibiotic pigment produced by Pseudomonas aeruginosa." ;
rdfs:subClassOf obo:CHEBI_35285 , obo:CHEBI_39201 .
obo:UBERON_0001948 a rdfs:Class ;
rdfs:label "regional part of spinal cord" ;
rdfs:comment "A multi-tissue structure that is part of a spinal cord." ;
rdfs:subClassOf obo:UBERON_0000073 , obo:UBERON_0000481 .
obo:UBERON_0004246 a rdfs:Class ;
rdfs:label "outflow tract smooth muscle" ;
rdfs:comment "A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 .
obo:GO_0055021 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle tissue growth" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac muscle growth." ;
rdfs:subClassOf obo:GO_0060420 , obo:GO_0065007 .
obo:CHEBI_64709 a rdfs:Class ;
rdfs:label "organic acid" ;
rdfs:comment "Any organic molecular entity that is acidic and contains carbon in covalent linkage." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:PHIPO_0001046 a rdfs:Class ;
rdfs:label "increased level of pathogen produced toxin within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen produced toxin usually present during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001043 .
obo:UBERON_0002555 a rdfs:Class ;
rdfs:label "intermediate hypothalamic region" ;
rdfs:comment "The portion of the hypothalamus located generally internal to the region of the infundibulum." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:CHEBI_100241 a rdfs:Class ;
rdfs:label "ciprofloxacin" ;
rdfs:comment "A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively." ;
rdfs:subClassOf obo:CHEBI_23765 , obo:CHEBI_26512 , obo:CHEBI_36709 , obo:CHEBI_46848 , obo:CHEBI_51454 , obo:CHEBI_86324 , obo:CHEBI_87211 .
obo:GO_0005975 a rdfs:Class ;
rdfs:label "carbohydrate metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0044238 .
obo:CHEBI_75283 a rdfs:Class ;
rdfs:label "miltefosine" ;
rdfs:comment "A phospholipid that is the hexadecyl monoester of phosphocholine." ;
rdfs:subClassOf obo:CHEBI_16247 , obo:CHEBI_36700 , obo:CHEBI_60911 .
obo:UBERON_0007390 a rdfs:Class ;
rdfs:label "pectoral appendage cartilage tissue" ;
rdfs:comment "A cartilage tissue that is part of a pectoral appendage." ;
rdfs:subClassOf obo:UBERON_0002418 , obo:UBERON_0007389 .
obo:GO_0050996 a rdfs:Class ;
rdfs:label "positive regulation of lipid catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." ;
rdfs:subClassOf obo:GO_0009896 , obo:GO_0045834 , obo:GO_0050994 , obo:GO_0065007 .
obo:CL_4300031 a rdfs:Class ;
rdfs:label "OPC-Oligo cell (Mmus)" ;
rdfs:comment "A cell of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:31 OPC-Oligo." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_0051655 a rdfs:Class ;
rdfs:label "maintenance of vesicle location" ;
rdfs:comment "Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0051648 , obo:GO_0051651 , obo:GO_0051657 .
obo:PHIPO_0000160 a rdfs:Class ;
rdfs:label "pathogen penetration across barrier phenotype"@en ;
rdfs:comment "A single species phenotype which affects the pathogen's ability to penetrate a given experimental substance/membrane in an in vitro assay." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:GO_0061152 a rdfs:Class ;
rdfs:label "trachea submucosa development" ;
rdfs:comment "The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0010893 a rdfs:Class ;
rdfs:label "positive regulation of steroid biosynthetic process" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ;
rdfs:subClassOf obo:GO_0045940 , obo:GO_0046889 , obo:GO_0050810 , obo:GO_0065007 .
obo:GO_0043940 a rdfs:Class ;
rdfs:label "regulation of sexual sporulation resulting in formation of a cellular spore" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis." ;
rdfs:subClassOf obo:GO_0034306 , obo:GO_0042173 , obo:GO_0065007 .
obo:GO_0045913 a rdfs:Class ;
rdfs:label "positive regulation of carbohydrate metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." ;
rdfs:subClassOf obo:GO_0006109 , obo:GO_0009893 , obo:GO_0065007 .
obo:CL_1000309 a rdfs:Class ;
rdfs:label "epicardial adipocyte" ;
rdfs:comment "An adipocyte that is part of the epicardial fat." ;
rdfs:subClassOf obo:CL_0000136 , obo:CL_0002494 .
obo:GO_0080134 a rdfs:Class ;
rdfs:label "regulation of response to stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 .
obo:UBERON_0005838 a rdfs:Class ;
rdfs:label "fasciculus of brain" ;
rdfs:comment "A fascicle that is part of a brain." ;
rdfs:subClassOf obo:UBERON_0001019 , obo:UBERON_0011215 .
obo:GO_0003354 a rdfs:Class ;
rdfs:label "negative regulation of cilium movement" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." ;
rdfs:subClassOf obo:GO_0003352 , obo:GO_0048523 , obo:GO_0065007 .
obo:PHIPO_0000207 a rdfs:Class ;
rdfs:label "loss of mutualism"@en ;
rdfs:comment "A phenotype in which the balance of symbiotic mutualism has been disrupted compared to the normal interaction and the endosymbiont organism is able to show greater biomass within the host and/or the formation of visible disease formation symptoms compared to the normal interaction." ;
rdfs:subClassOf obo:PHIPO_0000040 .
obo:PR_000001883 a rdfs:Class ;
rdfs:label "lysosome-associated membrane protein" ;
rdfs:comment "A protein with core architecture consisting of a Lysosome-associated membrane glycoprotein (Pfam:PF01299) domain. It is a single-pass type I membrane protein that shuttles between lysosomes, endosomes, and the plasma membrane." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0140154 a rdfs:Class ;
rdfs:label "chicken-wire-like collagen network" ;
rdfs:comment "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." ;
rdfs:subClassOf obo:GO_0098645 .
obo:GO_0044458 a rdfs:Class ;
rdfs:label "motile cilium assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a motile cilium." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0060271 .
obo:CHEBI_24836 a rdfs:Class ;
rdfs:label "inorganic oxide" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_25741 .
obo:GO_0061073 a rdfs:Class ;
rdfs:label "ciliary body morphogenesis" ;
rdfs:comment "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PHIPO_0001051 a rdfs:Class ;
rdfs:label "abnormal unicellular colony shape"@en ;
rdfs:comment "A single species phenotype where the shape of a colony of unicellular individuals is abnormal." ;
rdfs:subClassOf obo:PHIPO_0001049 .
obo:UBERON_0002316 a rdfs:Class ;
rdfs:label "white matter" ;
rdfs:comment "Neural tissue consisting of myelinated axons connecting grey matter areas of the central nervous system." ;
rdfs:subClassOf obo:UBERON_0011215 .
obo:GO_0043243 a rdfs:Class ;
rdfs:label "positive regulation of protein-containing complex disassembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ;
rdfs:subClassOf obo:GO_0043244 , obo:GO_0051130 , obo:GO_0065007 .
obo:GO_0043385 a rdfs:Class ;
rdfs:label "mycotoxin metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus." ;
rdfs:subClassOf obo:GO_0009404 .
obo:GO_0033371 a rdfs:Class ;
rdfs:label "T cell secretory granule organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0033363 .
obo:GO_0071806 a rdfs:Class ;
rdfs:label "protein transmembrane transport" ;
rdfs:comment "The process in which a protein is transported across a membrane." ;
rdfs:subClassOf obo:GO_0015031 , obo:GO_0055085 .
obo:UBERON_0017650 a rdfs:Class ;
rdfs:label "developing mesenchymal structure" ;
rdfs:comment "A mesenchyme-derived anatomical entity undergoing a transtion to become another structure." ;
rdfs:subClassOf obo:UBERON_0005423 .
obo:GO_0043939 a rdfs:Class ;
rdfs:label "negative regulation of sporulation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure." ;
rdfs:subClassOf obo:GO_0043937 , obo:GO_0051093 , obo:GO_0065007 .
obo:UBERON_0000030 a rdfs:Class ;
rdfs:label "lamina propria" ;
rdfs:comment "A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:PHIPO_0000198 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction transporter phenotype" ;
rdfs:comment "A pathogen host interaction phenotype which affects a transporter activity." .
obo:GO_0170043 a rdfs:Class ;
rdfs:label "non-proteinogenic amino acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0046394 , obo:GO_0170041 .
obo:CHEBI_83779 a rdfs:Class ;
rdfs:label "1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol" ;
rdfs:comment "A tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively." ;
rdfs:subClassOf obo:CHEBI_26878 , obo:CHEBI_35727 , obo:CHEBI_83403 .
obo:PHIPO_0000401 a rdfs:Class ;
rdfs:label "obsolete normal phialide morphology" .
obo:CHEBI_51702 a rdfs:Class ;
rdfs:label "enoate ester" ;
rdfs:comment "An α,β-unsaturated carboxylic ester of general formula R1R2C=CR3‒C(=O)OR4 (R4 ≠ H) in which the ester C=O function is conjugated to a C=C double bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_51737 , obo:CHEBI_78840 .
obo:UBERON_0007592 a rdfs:Class ;
rdfs:label "ciliated columnar epithelium" ;
rdfs:comment "Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000485 , obo:UBERON_0007601 .
obo:GO_0033604 a rdfs:Class ;
rdfs:label "negative regulation of catecholamine secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine." ;
rdfs:subClassOf obo:GO_0050433 , obo:GO_0051953 , obo:GO_0065007 , obo:GO_1903531 .
obo:UBERON_0000963 a rdfs:Class ;
rdfs:label "head sensillum" ;
rdfs:subClassOf obo:UBERON_0002536 .
obo:CHEBI_28971 a rdfs:Class ;
rdfs:label "ampicillin" ;
rdfs:comment "A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_88187 .
obo:GO_0062013 a rdfs:Class ;
rdfs:label "positive regulation of small molecule metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0062012 , obo:GO_0065007 .
obo:GO_1905608 a rdfs:Class ;
rdfs:label "positive regulation of presynapse assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of presynapse assembly." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1905606 .
obo:UBERON_0005428 a rdfs:Class ;
rdfs:label "vagal neural crest" ;
rdfs:comment "Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]." ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:UBERON_0002926 a rdfs:Class ;
rdfs:label "gustatory epithelium" ;
rdfs:comment "A sensory epithelium that is part of a gustatory system." ;
rdfs:subClassOf obo:UBERON_0006934 .
obo:GO_0051247 a rdfs:Class ;
rdfs:label "positive regulation of protein metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." ;
rdfs:subClassOf obo:GO_0010604 , obo:GO_0051246 , obo:GO_0065007 .
obo:GO_0034349 a rdfs:Class ;
rdfs:label "glial cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system." ;
rdfs:subClassOf obo:GO_0006915 .
obo:GO_0035700 a rdfs:Class ;
rdfs:label "astrocyte chemotaxis" ;
rdfs:comment "The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0043615 , obo:GO_0060326 .
obo:PHIPO_0000962 a rdfs:Class ;
rdfs:label "decreased filamentous growth on host surface"@en ;
rdfs:comment "A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is decreased." ;
rdfs:subClassOf obo:PHIPO_0000349 .
a rdfs:Class ;
rdfs:label "Globus pallidus, internal segment" ;
rdfs:subClassOf , obo:UBERON_0002477 .
obo:UBERON_0002200 a rdfs:Class ;
rdfs:label "vasculature of head" ;
rdfs:comment "Vasculature that is part of a head [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:CHEBI_26658 a rdfs:Class ;
rdfs:label "sesquiterpenoid" ;
rdfs:comment "Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." ;
rdfs:subClassOf obo:CHEBI_26873 .
obo:UBERON_0004734 a rdfs:Class ;
rdfs:label "gastrula" ;
rdfs:comment "Organism at the gastrula stage." ;
rdfs:subClassOf obo:UBERON_0000468 , obo:UBERON_0000922 .
obo:PHIPO_0000959 a rdfs:Class ;
rdfs:label "normal cellular melanin accumulation"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of melanin in a cell is normal." ;
rdfs:subClassOf obo:PHIPO_0000286 .
obo:UBERON_0001777 a rdfs:Class ;
rdfs:label "substantia propria of cornea" ;
rdfs:comment "The lamellated connective tissue of the cornea between the Bowman and Descemet membranes." ;
rdfs:subClassOf obo:UBERON_0003891 .
obo:CHEBI_26822 a rdfs:Class ;
rdfs:label "sulfide" ;
rdfs:comment "Any sulfur molecular entity that involves either covalently bonded or anionic sulfur." ;
rdfs:subClassOf obo:CHEBI_26835 .
obo:GO_0099501 a rdfs:Class ;
rdfs:label "exocytic vesicle membrane" ;
rdfs:comment "The lipid bilayer surrounding an exocytic vesicle." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0030658 .
obo:PHIPO_0001272 a rdfs:Class ;
rdfs:label "stunted growth"@en ;
rdfs:comment "A single species growth phenotype where there is a decrease in size of an entire multicellular organism." ;
rdfs:subClassOf obo:PHIPO_0000402 .
obo:GO_0045964 a rdfs:Class ;
rdfs:label "positive regulation of dopamine metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ;
rdfs:subClassOf obo:GO_0033240 , obo:GO_0042053 , obo:GO_0065007 .
obo:CHEBI_50313 a rdfs:Class ;
rdfs:label "onium cation" ;
rdfs:comment "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." ;
rdfs:subClassOf obo:CHEBI_50312 .
obo:UBERON_0003059 a rdfs:Class ;
rdfs:label "presomitic mesoderm" ;
rdfs:comment "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form." ;
rdfs:subClassOf obo:UBERON_0000061 , obo:UBERON_0005423 , obo:UBERON_0006598 .
obo:GO_0098971 a rdfs:Class ;
rdfs:label "anterograde dendritic transport of neurotransmitter receptor complex" ;
rdfs:comment "The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0097120 , obo:GO_0098937 .
obo:GO_0065008 a rdfs:Class ;
rdfs:label "regulation of biological quality" ;
rdfs:comment "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." ;
rdfs:subClassOf obo:GO_0065007 .
obo:UBERON_0002047 a rdfs:Class ;
rdfs:label "pontine raphe nucleus" ;
rdfs:comment "The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0006331 , obo:UBERON_0009662 .
obo:UBERON_0001668 a rdfs:Class ;
rdfs:label "cerebellar vein" ;
rdfs:comment "A vein that drains the cerebellum." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:GO_0009892 a rdfs:Class ;
rdfs:label "negative regulation of metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0048523 , obo:GO_0065007 .
obo:GO_0014006 a rdfs:Class ;
rdfs:label "regulation of microglia differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell." ;
rdfs:subClassOf obo:GO_0045649 , obo:GO_0045685 , obo:GO_0065007 .
obo:GO_0001992 a rdfs:Class ;
rdfs:label "regulation of systemic arterial blood pressure by vasopressin" ;
rdfs:comment "The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport." ;
rdfs:subClassOf obo:GO_0001990 .
obo:PHIPO_0000981 a rdfs:Class ;
rdfs:label "abnormal meiosis"@en ;
rdfs:comment "A reproductive process phenotype in which meiosis is abnormal. Meiosis refers specifically to the nuclear division phases of a meiotic cell cycle. (GO:0140013)." ;
rdfs:subClassOf obo:PHIPO_0000400 , obo:PHIPO_0000983 .
obo:PHIPO_0000865 a rdfs:Class ;
rdfs:label "sensitive to benzylpenicillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to benzylpenicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:PHIPO_0000539 a rdfs:Class ;
rdfs:label "resistance to ciprofloxacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ciprofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_33937 a rdfs:Class ;
rdfs:label "macronutrient" ;
rdfs:comment "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." ;
rdfs:subClassOf obo:CHEBI_33284 .
obo:PHIPO_0001182 a rdfs:Class ;
rdfs:label "normal level of deoxynivalenol"@en ;
rdfs:comment "A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001039 .
obo:GO_0030951 a rdfs:Class ;
rdfs:label "establishment or maintenance of microtubule cytoskeleton polarity" ;
rdfs:comment "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0000226 , obo:GO_0030952 .
obo:GO_0010560 a rdfs:Class ;
rdfs:label "positive regulation of glycoprotein biosynthetic process" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ;
rdfs:subClassOf obo:GO_0010557 , obo:GO_0010559 , obo:GO_0065007 , obo:GO_1903020 .
obo:PHIPO_0000472 a rdfs:Class ;
rdfs:label "normal pathogen asexual sporulation within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host where the process of pathogen asexual sporulation, the formation of spores derived from the products of an asexual cell division, is normal (GO:0030436)." ;
rdfs:subClassOf obo:PHIPO_0000442 .
obo:CHEBI_36386 a rdfs:Class ;
rdfs:label "dichloroacetic acid" ;
rdfs:comment "An organochlorine compound comprising acetic acid carrying two chloro substituents at the 2-position. It occurs in nature in seaweed, Asparagopsis taxiformis." ;
rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_36683 .
obo:GO_0015931 a rdfs:Class ;
rdfs:label "nucleobase-containing compound transport" ;
rdfs:comment "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0071705 .
obo:CHEBI_87208 a rdfs:Class ;
rdfs:label "anilinopyrimidine fungicide" ;
rdfs:comment "Any pyrimidine fungicide in which the pyrimidine ring is substituted by the nitrogen of an aniline moiety." ;
rdfs:subClassOf obo:CHEBI_87207 .
obo:UBERON_0016554 a rdfs:Class ;
rdfs:label "white matter of midbrain" ;
rdfs:comment "A white matter that is part of the midbrain." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0003544 .
obo:GO_1905384 a rdfs:Class ;
rdfs:label "regulation of protein localization to presynapse" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to presynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902473 .
obo:GO_0032379 a rdfs:Class ;
rdfs:label "positive regulation of intracellular lipid transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells." ;
rdfs:subClassOf obo:GO_0032370 , obo:GO_0032377 , obo:GO_0032388 , obo:GO_0065007 .
obo:UBERON_0036661 a rdfs:Class ;
rdfs:label "wall of ventricular system of brain" ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0005358 .
obo:UBERON_0005956 a rdfs:Class ;
rdfs:label "outflow part of left ventricle" ;
rdfs:comment "Anterosuperior fibrous portion of the left ventricle that connects to the ascending aorta." ;
rdfs:subClassOf obo:UBERON_0005337 .
obo:UBERON_0004016 a rdfs:Class ;
rdfs:label "dermatome" ;
rdfs:comment "A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells." ;
rdfs:subClassOf obo:UBERON_0017650 .
obo:CHEBI_33608 a rdfs:Class ;
rdfs:label "hydrogen molecular entity" ;
rdfs:subClassOf obo:CHEBI_33674 .
obo:CL_0000549 a rdfs:Class ;
rdfs:label "basophilic erythroblast" ;
rdfs:comment "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers." ;
rdfs:subClassOf obo:CL_0000765 .
obo:GO_2000271 a rdfs:Class ;
rdfs:label "positive regulation of fibroblast apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0065007 , obo:GO_2000269 .
obo:GO_0010975 a rdfs:Class ;
rdfs:label "regulation of neuron projection development" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120035 .
obo:PHIPO_0000517 a rdfs:Class ;
rdfs:label "lipid droplets present in increased numbers"@en ;
rdfs:comment "A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain more lipid droplets than normal." ;
rdfs:subClassOf obo:PHIPO_0000474 .
obo:PHIPO_0000373 a rdfs:Class ;
rdfs:label "increased number of pathogen penetration structure when near host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the frequency of occurrence of pathogen penetration stuctures near the host are increased." ;
rdfs:subClassOf obo:PHIPO_0000369 .
obo:CHEBI_32955 a rdfs:Class ;
rdfs:label "epoxide" ;
rdfs:comment "Any cyclic ether in which the oxygen atom forms part of a 3-membered ring." ;
rdfs:subClassOf obo:CHEBI_37407 .
obo:PHIPO_0000781 a rdfs:Class ;
rdfs:label "sensitive to trimethoprim"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to trimethoprim. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0036230 a rdfs:Class ;
rdfs:label "granulocyte activation" ;
rdfs:comment "The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0002274 .
obo:PHIPO_0000803 a rdfs:Class ;
rdfs:label "sensitive to ketoconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ketoconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0021896 a rdfs:Class ;
rdfs:label "forebrain astrocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0048708 .
obo:GO_0051154 a rdfs:Class ;
rdfs:label "negative regulation of striated muscle cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051148 , obo:GO_0051153 , obo:GO_0065007 .
obo:CHEBI_75769 a rdfs:Class ;
rdfs:label "B vitamin" ;
rdfs:comment "Any member of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises of vitamin B1, B2, B3, B5, B6, B7, B9, and B12 (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such)." ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_36963 .
obo:UBERON_0006562 a rdfs:Class ;
rdfs:label "pharynx" ;
rdfs:comment "The pharynx is the part of the digestive system immediately posterior to the mouth[GO]." ;
rdfs:subClassOf obo:UBERON_0004921 .
obo:CHEBI_26912 a rdfs:Class ;
rdfs:label "oxolanes" ;
rdfs:comment "Any oxacycle having an oxolane (tetrahydrofuran) skeleton." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 .
obo:GO_0021680 a rdfs:Class ;
rdfs:label "cerebellar Purkinje cell layer development" ;
rdfs:comment "The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0003144 a rdfs:Class ;
rdfs:label "embryonic heart tube formation" ;
rdfs:comment "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." ;
rdfs:subClassOf obo:GO_0001838 , obo:GO_0048646 .
obo:UBERON_0011270 a rdfs:Class ;
rdfs:label "dorsal trunk" ;
rdfs:comment "The part of the trunk that is in the dorsum[cjm]." ;
rdfs:subClassOf obo:UBERON_0009569 .
obo:PHIPO_0000120 a rdfs:Class ;
rdfs:label "premature pathogen growth after penetration of the barrier"@en ;
rdfs:comment "A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay begins sooner than normal." ;
rdfs:subClassOf obo:PHIPO_0000031 .
obo:GO_0097734 a rdfs:Class ;
rdfs:label "extracellular exosome biogenesis" ;
rdfs:comment "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." ;
rdfs:subClassOf obo:GO_0140112 .
obo:PHIPO_0000430 a rdfs:Class ;
rdfs:label "carbohydrate binding phenotype"@en ;
rdfs:comment "A single species molecular function phenotype that affects carbohydrate binding. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000158 .
obo:UBERON_0001015 a rdfs:Class ;
rdfs:label "musculature" ;
rdfs:comment "A subdivision of the muscular system corresponding to a subdisivision of an organism." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:UBERON_0004768 a rdfs:Class ;
rdfs:label "bone of lower jaw" ;
rdfs:comment "Any bone that is part of the lower jaw skeleton. This includes (when present): the dentary/mandible, the articular, the splenial, the suprangular." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0010313 , obo:UBERON_0012360 .
obo:GO_0003210 a rdfs:Class ;
rdfs:label "cardiac atrium formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." ;
rdfs:subClassOf obo:GO_0003207 , obo:GO_0048646 .
obo:PHIPO_0000770 a rdfs:Class ;
rdfs:label "sensitive to mecillinam"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to mecillinam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:PHIPO_0000098 a rdfs:Class ;
rdfs:label "normal meiosis II"@en ;
rdfs:comment "A reproductive process phenotype in which the second meiotic nuclear division is normal (i.e. indistinguishable from wild type)(GO:0007135)." ;
rdfs:subClassOf obo:PHIPO_0000982 .
obo:CL_0000113 a rdfs:Class ;
rdfs:label "mononuclear phagocyte" ;
rdfs:comment "A vertebrate phagocyte with a single nucleus." ;
rdfs:subClassOf obo:CL_0000518 , obo:CL_0000842 .
obo:GO_0140244 a rdfs:Class ;
rdfs:label "regulation of translation at presynapse" ;
rdfs:comment "Any process that regulates translation occurring at the presynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0140243 .
obo:PHIPO_0001024 a rdfs:Class ;
rdfs:label "increased cellular cAMP level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of cyclic AMP measured in a cell is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001022 , obo:PHIPO_0001036 .
obo:GO_0010160 a rdfs:Class ;
rdfs:label "formation of animal organ boundary" ;
rdfs:comment "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues." ;
rdfs:subClassOf obo:GO_0003002 , obo:GO_0048859 .
obo:UBERON_0005076 a rdfs:Class ;
rdfs:label "hindbrain-spinal cord boundary" ;
rdfs:comment "An anatomical boundary that adjacent_to a hindbrain and adjacent_to a spinal cord." ;
rdfs:subClassOf obo:UBERON_0007651 .
obo:CHEBI_64246 a rdfs:Class ;
rdfs:label "tunicamycin A2" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a tetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:CHEBI_24621 a rdfs:Class ;
rdfs:label "hormone" ;
rdfs:comment "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." ;
rdfs:subClassOf obo:CHEBI_33280 , obo:CHEBI_48705 .
obo:GO_0032544 a rdfs:Class ;
rdfs:label "plastid translation" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code." ;
rdfs:subClassOf obo:GO_0006412 , obo:GO_0009657 .
obo:GO_0031270 a rdfs:Class ;
rdfs:label "pseudopodium retraction" ;
rdfs:comment "The myosin-based contraction and retraction of a pseudopodium." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0031268 .
obo:GO_0006581 a rdfs:Class ;
rdfs:label "acetylcholine catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline." ;
rdfs:subClassOf obo:GO_0008291 , obo:GO_0009056 .
obo:UBERON_0007808 a rdfs:Class ;
rdfs:label "adipose tissue of abdominal region" ;
rdfs:comment "Adipose tissue that is located in the abdominal region. This includes any subcutaneous fat, visceral fat or encapsulated adipose tissue depots." ;
rdfs:subClassOf obo:UBERON_0001013 , obo:UBERON_0003567 .
obo:GO_0044380 a rdfs:Class ;
rdfs:label "protein localization to cytoskeleton" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within the cytoskeleton." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033365 .
obo:GO_1903707 a rdfs:Class ;
rdfs:label "negative regulation of hemopoiesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis." ;
rdfs:subClassOf obo:GO_0002683 , obo:GO_0010721 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1903706 .
obo:GO_1903327 a rdfs:Class ;
rdfs:label "negative regulation of tRNA metabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051253 , obo:GO_0065007 , obo:GO_1903326 .
obo:CHEBI_76727 a rdfs:Class ;
rdfs:label "EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*)." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:GO_0031348 a rdfs:Class ;
rdfs:label "negative regulation of defense response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." ;
rdfs:subClassOf obo:GO_0031347 , obo:GO_0048585 , obo:GO_0065007 .
obo:GO_0090435 a rdfs:Class ;
rdfs:label "protein localization to nuclear envelope" ;
rdfs:comment "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0034504 .
obo:UBERON_0004848 a rdfs:Class ;
rdfs:label "respiratory system arterial endothelium" ;
rdfs:comment "An endothelium of artery that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001917 , obo:UBERON_0004702 .
obo:PHIPO_0001436 a rdfs:Class ;
rdfs:label "normal growth on caspofungin" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to caspofungin (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:NCBITaxon_9989 a rdfs:Class ;
rdfs:label "Rodentia" ;
rdfs:subClassOf obo:NCBITaxon_314147 .
obo:GO_0009888 a rdfs:Class ;
rdfs:label "tissue development" ;
rdfs:comment "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_1901375 a rdfs:Class ;
rdfs:label "acetate ester transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of an acetate ester from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 .
obo:GO_0099578 a rdfs:Class ;
rdfs:label "regulation of translation at postsynapse, modulating synaptic transmission" ;
rdfs:comment "Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0099170 , obo:GO_0099547 , obo:GO_0140245 .
obo:CHEBI_78608 a rdfs:Class ;
rdfs:label "alpha-amino-acid zwitterion" ;
rdfs:comment "An amino acid-zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:GO_0120331 a rdfs:Class ;
rdfs:label "endothelial tube formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of an endothelial tube." ;
rdfs:subClassOf obo:GO_0035148 , obo:GO_0072175 .
obo:GO_0045606 a rdfs:Class ;
rdfs:label "positive regulation of epidermal cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation." ;
rdfs:subClassOf obo:GO_0030858 , obo:GO_0045604 , obo:GO_0045684 , obo:GO_0065007 .
obo:UBERON_0009199 a rdfs:Class ;
rdfs:label "facial suture" ;
rdfs:comment "Any suture between facial bones." ;
rdfs:subClassOf obo:UBERON_0009198 .
obo:UBERON_0001042 a rdfs:Class ;
rdfs:label "chordate pharynx" ;
rdfs:comment "A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]." ;
rdfs:subClassOf obo:UBERON_0006562 .
obo:GO_0035855 a rdfs:Class ;
rdfs:label "megakaryocyte development" ;
rdfs:comment "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0061515 .
obo:GO_0035929 a rdfs:Class ;
rdfs:label "steroid hormone secretion" ;
rdfs:comment "The regulated release of any steroid that acts as a hormone into the circulatory system." ;
rdfs:subClassOf obo:GO_0046879 , obo:GO_0046903 , obo:GO_0140353 .
obo:CHEBI_8733 a rdfs:Class ;
rdfs:label "Quinupristin-dalfopristin" ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:CHEBI_33696 a rdfs:Class ;
rdfs:label "nucleic acid" ;
rdfs:comment "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ;
rdfs:subClassOf obo:CHEBI_15986 .
obo:UBERON_0005316 a rdfs:Class ;
rdfs:label "endocardial endothelium" ;
rdfs:comment "The endothelial lining of the endocardium." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0008307 .
obo:CHEBI_25435 a rdfs:Class ;
rdfs:label "mutagen" ;
rdfs:comment "An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution." ;
rdfs:subClassOf obo:CHEBI_50902 .
obo:GO_0002292 a rdfs:Class ;
rdfs:label "T cell differentiation involved in immune response" ;
rdfs:comment "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." ;
rdfs:subClassOf obo:GO_0002286 , obo:GO_0030217 .
obo:PHIPO_0000124 a rdfs:Class ;
rdfs:label "obsolete abnormal penetration structure present" .
obo:PHIPO_0000323 a rdfs:Class ;
rdfs:label "obsolete loss of effector of pathogenicity activation of host defense" ;
rdfs:comment "The pathogen effector entity has lost the ability to activate host defense." .
a rdfs:Class ;
rdfs:label "Basic cell groups and regions" ;
rdfs:subClassOf , obo:UBERON_0002616 .
obo:GO_0022408 a rdfs:Class ;
rdfs:label "negative regulation of cell-cell adhesion" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." ;
rdfs:subClassOf obo:GO_0007162 , obo:GO_0022407 , obo:GO_0065007 .
obo:PHIPO_0000999 a rdfs:Class ;
rdfs:label "abnormal pathogen morphology during colonization of host"@en ;
rdfs:comment "A pathogen host interaction phenotype where the morphology of the pathogen during host colonization is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0000998 .
obo:GO_0051222 a rdfs:Class ;
rdfs:label "positive regulation of protein transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051050 , obo:GO_0051223 , obo:GO_0065007 , obo:GO_1904951 .
obo:CHEBI_35352 a rdfs:Class ;
rdfs:label "organonitrogen compound" ;
rdfs:comment "Any heteroorganic entity containing at least one carbon-nitrogen bond." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_51143 .
obo:UBERON_0011164 a rdfs:Class ;
rdfs:label "neurocranium bone" ;
rdfs:comment "A bone that is part of a neurocranium [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0003457 , obo:UBERON_0004766 .
obo:GO_0000003 a rdfs:Class ;
rdfs:label "reproduction" ;
rdfs:comment "OBSOLETE. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." ;
rdfs:subClassOf obo:GO_0008150 .
obo:PHIPO_0000898 a rdfs:Class ;
rdfs:label "sensitive to nalidixic acid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to nalidixic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0007292 a rdfs:Class ;
rdfs:label "female gamete generation" ;
rdfs:comment "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." ;
rdfs:subClassOf obo:GO_0007276 .
obo:GO_0014858 a rdfs:Class ;
rdfs:label "positive regulation of skeletal muscle cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0014857 , obo:GO_0065007 .
obo:CL_1000331 a rdfs:Class ;
rdfs:label "serous cell of epithelium of bronchus" ;
rdfs:comment "A serous secreting cell that is part of the epithelium of bronchus." ;
rdfs:subClassOf obo:CL_0000313 , obo:CL_0019001 .
obo:GO_2000027 a rdfs:Class ;
rdfs:label "regulation of animal organ morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of animal organ morphogenesis." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0065007 .
obo:UBERON_0002871 a rdfs:Class ;
rdfs:label "hypoglossal nucleus" ;
rdfs:comment "Nucleus forming a longitudinal cell column in the medulla, close beneath the floor of the 4th ventricle, containing motor neurons that innervate the muscles of the tongue (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 453)." ;
rdfs:subClassOf obo:UBERON_0000126 , obo:UBERON_0007635 .
obo:GO_0060536 a rdfs:Class ;
rdfs:label "cartilage morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of cartilage are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 , obo:GO_0048729 .
obo:UBERON_0008193 a rdfs:Class ;
rdfs:label "pneumatized bone" ;
rdfs:comment "A bone that is hollow or contains many air cells, such as the mastoid process of the temporal bone[TMD]." ;
rdfs:subClassOf obo:UBERON_0001474 .
obo:GO_0090685 a rdfs:Class ;
rdfs:label "RNA localization to nucleus" ;
rdfs:comment "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus." ;
rdfs:subClassOf obo:GO_0006403 .
obo:GO_0090741 a rdfs:Class ;
rdfs:label "pigment granule membrane" ;
rdfs:comment "Any membrane that is part of a pigment granule." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0030659 , obo:GO_0098588 .
obo:UBERON_0002410 a rdfs:Class ;
rdfs:label "autonomic nervous system" ;
rdfs:comment "The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:PHIPO_0001070 a rdfs:Class ;
rdfs:label "host organism viability with pathogen phenotype"@en ;
rdfs:comment "A pathogen host interaction organism level phenotype which affects the viability of an individual host organism in the presence of a pathogen." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:UBERON_0001766 a rdfs:Class ;
rdfs:label "anterior chamber of eyeball" ;
rdfs:comment "The space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens." ;
rdfs:subClassOf obo:UBERON_0006311 .
obo:UBERON_0034922 a rdfs:Class ;
rdfs:label "cell cluster" ;
rdfs:comment "A cluster of cells, largely surrounded by a morphological boundary." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:GO_1903012 a rdfs:Class ;
rdfs:label "positive regulation of bone development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of bone development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1903010 .
obo:GO_1901608 a rdfs:Class ;
rdfs:label "regulation of vesicle transport along microtubule" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902513 .
obo:PHIPO_0000506 a rdfs:Class ;
rdfs:label "obsolete single species" .
obo:GO_0048709 a rdfs:Class ;
rdfs:label "oligodendrocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system." ;
rdfs:subClassOf obo:GO_0010001 , obo:GO_0030154 .
obo:GO_0002726 a rdfs:Class ;
rdfs:label "positive regulation of T cell cytokine production" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production." ;
rdfs:subClassOf obo:GO_0002711 , obo:GO_0002720 , obo:GO_0002724 , obo:GO_0065007 .
obo:CHEBI_83072 a rdfs:Class ;
rdfs:label "EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor" ;
rdfs:comment "An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of succinate dehydrogenase (quinone), EC 1.3.5.1." ;
rdfs:subClassOf obo:CHEBI_77102 .
obo:GO_0006694 a rdfs:Class ;
rdfs:label "steroid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification." ;
rdfs:subClassOf obo:GO_0008202 , obo:GO_0008610 , obo:GO_0009058 .
obo:GO_0045185 a rdfs:Class ;
rdfs:label "maintenance of protein location" ;
rdfs:comment "Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away." ;
rdfs:subClassOf obo:GO_0051235 .
obo:GO_0061448 a rdfs:Class ;
rdfs:label "connective tissue development" ;
rdfs:comment "The progression of a connective tissue over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0009888 , obo:GO_0048856 .
obo:UBERON_0014790 a rdfs:Class ;
rdfs:label "lingual septum" ;
rdfs:comment "The lingual septum consists of a vertical layer of fibrous tissue, extending throughout the entire length of the median plane of the tongue, though not quite reaching the dorsum. It is thicker behind than in front, and occasionally contains a small fibrocartilage, about 6 mm. in length. It is well displayed by making a vertical section across the organ." ;
rdfs:subClassOf obo:UBERON_0003037 .
obo:GO_0033240 a rdfs:Class ;
rdfs:label "positive regulation of amine metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0033238 , obo:GO_0065007 .
obo:CL_0002031 a rdfs:Class ;
rdfs:label "hematopoietic lineage restricted progenitor cell" ;
rdfs:comment "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000988 , obo:CL_0008001 .
obo:GO_1904170 a rdfs:Class ;
rdfs:label "regulation of bleb assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of bleb assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120032 .
obo:UBERON_0001084 a rdfs:Class ;
rdfs:label "skin of head" ;
rdfs:comment "A zone of skin that is part of a head [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0012180 .
obo:CHEBI_62419 a rdfs:Class ;
rdfs:label "(1R,2S)-epoxypropylphosphonate(2-)" ;
rdfs:comment "An organophosphonate oxoanion obtained by deprotonation of the two phosphonate OH groups of (1R,2S)-epoxypropylphosphonic acid." ;
rdfs:subClassOf obo:CHEBI_71285 .
obo:PHIPO_0000234 a rdfs:Class ;
rdfs:label "pathogen deoxynivalenol within host absent"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the pathogen produced deoxynivalenol usually present during infection is absent or at a level too low to detect." ;
rdfs:subClassOf obo:PHIPO_0001047 .
obo:CHEBI_33635 a rdfs:Class ;
rdfs:label "polycyclic compound" ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:GO_0005886 a rdfs:Class ;
rdfs:label "plasma membrane" ;
rdfs:comment "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." ;
rdfs:subClassOf obo:GO_0016020 .
obo:GO_0021531 a rdfs:Class ;
rdfs:label "spinal cord radial glial cell differentiation" ;
rdfs:comment "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0021515 , obo:GO_0030154 , obo:GO_0060019 .
obo:GO_0030162 a rdfs:Class ;
rdfs:label "regulation of proteolysis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein." ;
rdfs:subClassOf obo:GO_0051246 , obo:GO_0065007 .
obo:PHIPO_0000399 a rdfs:Class ;
rdfs:label "obsolete abnormal phialide morphology" .
obo:GO_0090301 a rdfs:Class ;
rdfs:label "negative regulation of neural crest formation" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." ;
rdfs:subClassOf obo:GO_0010719 , obo:GO_0065007 , obo:GO_0090299 .
obo:GO_0031115 a rdfs:Class ;
rdfs:label "negative regulation of microtubule polymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." ;
rdfs:subClassOf obo:GO_0031111 , obo:GO_0031113 , obo:GO_0032272 , obo:GO_0065007 , obo:GO_1902904 .
obo:UBERON_0005062 a rdfs:Class ;
rdfs:label "neural fold" ;
rdfs:comment "One of the two elevated edges of the neural groove[GO,MP]." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005157 , obo:UBERON_0005291 , obo:UBERON_0015212 .
obo:GO_2001234 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic signaling pathway" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway." ;
rdfs:subClassOf obo:GO_0009968 , obo:GO_0043066 , obo:GO_0065007 , obo:GO_2001233 .
obo:GO_0034309 a rdfs:Class ;
rdfs:label "primary alcohol biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." ;
rdfs:subClassOf obo:GO_0034308 , obo:GO_0046165 .
obo:UBERON_0002081 a rdfs:Class ;
rdfs:label "cardiac atrium" ;
rdfs:comment "Cardiac chamber in which blood enters the heart." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0004151 .
obo:CL_0011028 a rdfs:Class ;
rdfs:label "olfactory ensheathing cell" ;
rdfs:comment "A neural-crest derived glial cell that supports the growth and survival of primary olfactory neuroons from the neuroepithelium in the nasal cavity to the brain by encasing large bundles of numerous unmyelinated axons." ;
rdfs:subClassOf obo:CL_0000125 .
obo:GO_0006516 a rdfs:Class ;
rdfs:label "glycoprotein catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0009100 , obo:GO_0030163 , obo:GO_1901136 .
obo:GO_1902117 a rdfs:Class ;
rdfs:label "positive regulation of organelle assembly" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of organelle assembly." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0044089 , obo:GO_0065007 , obo:GO_1902115 .
obo:GO_0002687 a rdfs:Class ;
rdfs:label "positive regulation of leukocyte migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of leukocyte migration." ;
rdfs:subClassOf obo:GO_0002684 , obo:GO_0002685 , obo:GO_0030335 , obo:GO_0065007 .
obo:UBERON_0004362 a rdfs:Class ;
rdfs:label "pharyngeal arch 1" ;
rdfs:comment "The first of the series of pharyngeal arches that develop into jaw bones or their homologs, and their associated nerves and arteries." ;
rdfs:subClassOf obo:UBERON_0002539 .
obo:GO_0006404 a rdfs:Class ;
rdfs:label "RNA import into nucleus" ;
rdfs:comment "The import of RNA from the cytoplasm to the nucleus." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0050658 , obo:GO_0051170 .
obo:CHEBI_33839 a rdfs:Class ;
rdfs:label "macromolecule" ;
rdfs:comment "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:CHEBI_36357 .
obo:CL_0000034 a rdfs:Class ;
rdfs:label "stem cell" ;
rdfs:comment "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0011115 .
obo:GO_0019219 a rdfs:Class ;
rdfs:label "regulation of nucleobase-containing compound metabolic process" ;
rdfs:comment "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080090 .
obo:CHEBI_31286 a rdfs:Class ;
rdfs:label "bifonazole" ;
rdfs:comment "A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87069 .
obo:CHEBI_17833 a rdfs:Class ;
rdfs:label "gentamycin" ;
rdfs:comment "Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp." ;
rdfs:subClassOf obo:CHEBI_22479 , obo:CHEBI_22507 .
obo:GO_1904124 a rdfs:Class ;
rdfs:label "microglial cell migration" ;
rdfs:comment "The orderly movement of a microglial cell from one site to another." ;
rdfs:subClassOf obo:GO_0008347 , obo:GO_0016477 , obo:GO_1905517 .
obo:CHEBI_76808 a rdfs:Class ;
rdfs:label "EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor" ;
rdfs:comment "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*)." ;
rdfs:subClassOf obo:CHEBI_76764 .
obo:GO_0070227 a rdfs:Class ;
rdfs:label "lymphocyte apoptotic process" ;
rdfs:comment "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0071887 .
obo:GO_0006706 a rdfs:Class ;
rdfs:label "steroid catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ;
rdfs:subClassOf obo:GO_0008202 , obo:GO_0009056 , obo:GO_0016042 .
obo:CL_0002598 a rdfs:Class ;
rdfs:label "bronchial smooth muscle cell" ;
rdfs:comment "Any smooth muscle cell that is part of some bronchus." ;
rdfs:subClassOf obo:CL_0000192 , obo:CL_0019019 .
obo:CHEBI_51959 a rdfs:Class ;
rdfs:label "organic tricyclic compound" ;
rdfs:subClassOf obo:CHEBI_51958 .
obo:GO_0001873 a rdfs:Class ;
rdfs:label "polysaccharide immune receptor activity" ;
rdfs:comment "Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ;
rdfs:subClassOf obo:GO_0038023 , obo:GO_0038187 .
obo:PHIPO_0000353 a rdfs:Class ;
rdfs:label "obsolete normal penetration of host by pathogen" ;
rdfs:comment "A pathogen growth with host phenotype in which the pathogen penetration into the host is normal (i.e. indistinguishable from wild type)." .
obo:GO_2000767 a rdfs:Class ;
rdfs:label "positive regulation of cytoplasmic translation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cytoplasmic translation." ;
rdfs:subClassOf obo:GO_0045727 , obo:GO_0065007 , obo:GO_2000765 .
obo:GO_0097096 a rdfs:Class ;
rdfs:label "facial suture morphogenesis" ;
rdfs:comment "The process in which any suture between facial bones is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0097094 .
obo:GO_1902738 a rdfs:Class ;
rdfs:label "regulation of chondrocyte differentiation involved in endochondral bone morphogenesis" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." ;
rdfs:subClassOf obo:GO_0032330 , obo:GO_0065007 , obo:GO_1903010 , obo:GO_2000027 .
obo:PR_000001013 a rdfs:Class ;
rdfs:label "integrin alpha-X" ;
rdfs:comment "An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis." ;
rdfs:subClassOf obo:PR_000001005 .
obo:CHEBI_149552 a rdfs:Class ;
rdfs:label "emetic" ;
rdfs:comment "Any agent that induces nausea and vomiting." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_2001053 a rdfs:Class ;
rdfs:label "regulation of mesenchymal cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:CHEBI_45285 a rdfs:Class ;
rdfs:label "pyrazinecarboxamide" ;
rdfs:comment "A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis." ;
rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_38314 , obo:CHEBI_83628 .
obo:GO_0006309 a rdfs:Class ;
rdfs:label "apoptotic DNA fragmentation" ;
rdfs:comment "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments." ;
rdfs:subClassOf obo:GO_0006308 .
obo:GO_0043209 a rdfs:Class ;
rdfs:label "myelin sheath" ;
rdfs:comment "An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0048813 a rdfs:Class ;
rdfs:label "dendrite morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a dendrite are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048812 .
obo:UBERON_0002378 a rdfs:Class ;
rdfs:label "muscle of abdomen" ;
rdfs:comment "Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis." ;
rdfs:subClassOf obo:UBERON_0003833 , obo:UBERON_0005172 , obo:UBERON_0014892 .
obo:CHEBI_15366 a rdfs:Class ;
rdfs:label "acetic acid" ;
rdfs:comment "A simple monocarboxylic acid containing two carbons." ;
rdfs:subClassOf obo:CHEBI_25384 .
obo:PHIPO_0001384 a rdfs:Class ;
rdfs:label "normal growth on fenpiclonil" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to fenpiclonil (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_63490 a rdfs:Class ;
rdfs:label "explosive" ;
rdfs:comment "A substance capable of undergoing rapid and highly exothermic decomposition." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:CL_0000617 a rdfs:Class ;
rdfs:label "GABAergic neuron" ;
rdfs:comment "A neuron that uses GABA as a vesicular neurotransmitter" ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000540 .
obo:UBERON_0003076 a rdfs:Class ;
rdfs:label "posterior neural tube" ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:CHEBI_48848 a rdfs:Class ;
rdfs:label "erythronolide A" ;
rdfs:subClassOf obo:CHEBI_23955 .
a rdfs:Class ;
rdfs:label "Cerebral nuclei" ;
rdfs:subClassOf , obo:UBERON_8440012 .
obo:GO_0051493 a rdfs:Class ;
rdfs:label "regulation of cytoskeleton organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:CHEBI_58549 a rdfs:Class ;
rdfs:label "kanamycin B(5+)" ;
rdfs:comment "An organic cation that is the pentacation of kanamycin B, obtained by protonation of the primary amino groups." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_1904957 a rdfs:Class ;
rdfs:label "negative regulation of midbrain dopaminergic neuron differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904339 , obo:GO_1904956 .
obo:CHEBI_51308 a rdfs:Class ;
rdfs:label "dinitrile" ;
rdfs:comment "A dinitrile is a compound containing two nitrile groups." ;
rdfs:subClassOf obo:CHEBI_18379 .
obo:PR_P25918 a rdfs:Class ;
rdfs:label "B-lymphocyte antigen CD19 (mouse)" ;
rdfs:comment "A CD19 molecule that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001002 , obo:PR_000029032 .
obo:CHEBI_86328 a rdfs:Class ;
rdfs:label "antifungal agrochemical" ;
rdfs:comment "Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties." ;
rdfs:subClassOf obo:CHEBI_24127 , obo:CHEBI_33286 .
obo:CHEBI_33856 a rdfs:Class ;
rdfs:label "aromatic amino acid" ;
rdfs:comment "An amino acid whose structure includes an aromatic ring." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_33709 .
obo:GO_0001653 a rdfs:Class ;
rdfs:label "peptide receptor activity" ;
rdfs:comment "Combining with an extracellular or intracellular peptide to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0038023 .
obo:GO_1902570 a rdfs:Class ;
rdfs:label "protein localization to nucleolus" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a nucleolus." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0034504 .
obo:GO_0048632 a rdfs:Class ;
rdfs:label "negative regulation of skeletal muscle tissue growth" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth." ;
rdfs:subClassOf obo:GO_0048631 , obo:GO_0048640 , obo:GO_0065007 .
obo:UBERON_0015152 a rdfs:Class ;
rdfs:label "gland of ocular region" ;
rdfs:comment "A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:PHIPO_0000829 a rdfs:Class ;
rdfs:label "sensitive to paromomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to paromomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0015833 a rdfs:Class ;
rdfs:label "peptide transport" ;
rdfs:comment "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0042886 .
obo:CHEBI_26836 a rdfs:Class ;
rdfs:label "sulfuric acid" ;
rdfs:comment "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." ;
rdfs:subClassOf obo:CHEBI_33402 .
obo:GO_0090291 a rdfs:Class ;
rdfs:label "negative regulation of osteoclast proliferation" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070664 , obo:GO_0090289 .
obo:GO_0050771 a rdfs:Class ;
rdfs:label "negative regulation of axonogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis." ;
rdfs:subClassOf obo:GO_0010977 , obo:GO_0050768 , obo:GO_0050770 , obo:GO_0065007 .
obo:GO_1901954 a rdfs:Class ;
rdfs:label "regulation of retrograde dense core granule transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of retrograde dense core granule transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901608 , obo:GO_1904809 , obo:GO_2001017 .
obo:GO_0008641 a rdfs:Class ;
rdfs:label "ubiquitin-like modifier activating enzyme activity" ;
rdfs:comment "Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond." ;
rdfs:subClassOf obo:GO_0016877 , obo:GO_0140096 , obo:GO_0140657 .
obo:BFO_0000020 a rdfs:Class ;
rdfs:label "specifically dependent continuant"@en ;
rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:CHEBI_24650 a rdfs:Class ;
rdfs:label "hydroxamic acid" ;
rdfs:comment "A compound, RkE(=O)lNHOH, derived from an oxoacid RkE(=O)l(OH) (l ≠ 0) by replacing ‒OH with ‒NHOH, and derivatives thereof. Specific examples of hydroxamic acids are preferably named as N-hydroxy amides." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:UBERON_0012375 a rdfs:Class ;
rdfs:label "subserosa" ;
rdfs:comment "A layer of tissue between the muscularis and serosa." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:GO_0110118 a rdfs:Class ;
rdfs:label "negative regulation of compound eye photoreceptor cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation." ;
rdfs:subClassOf obo:GO_0046533 , obo:GO_0065007 , obo:GO_0110116 .
obo:PHIPO_0001330 a rdfs:Class ;
rdfs:label "normal growth on thiram"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to thiram (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0034763 a rdfs:Class ;
rdfs:label "negative regulation of transmembrane transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0034762 , obo:GO_0048523 , obo:GO_0051051 , obo:GO_0065007 .
obo:PHIPO_0000388 a rdfs:Class ;
rdfs:label "resistance to azoxystrobin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to azoxystrobin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000576 .
obo:PHIPO_0000227 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction secondary metabolic process phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." .
obo:CHEBI_132157 a rdfs:Class ;
rdfs:label "hydroxy-1,4-naphthoquinone" ;
rdfs:comment "Any member of the class of 1,4-naphthoquinones in which the naphthoquinone moiety is substituted by at least one hydroxy group." ;
rdfs:subClassOf obo:CHEBI_132142 , obo:CHEBI_132155 .
obo:GO_0048146 a rdfs:Class ;
rdfs:label "positive regulation of fibroblast proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0048145 , obo:GO_0065007 .
obo:UBERON_0002092 a rdfs:Class ;
rdfs:label "brain dura mater" ;
rdfs:comment "The fibrous membrane forming the outer of the three coverings that surrounds the brain within the cranial cavity; consists of two layers including the periosteal layer and the meningeal layer." ;
rdfs:subClassOf obo:UBERON_0002363 , obo:UBERON_0003547 .
obo:GO_0032240 a rdfs:Class ;
rdfs:label "negative regulation of nucleobase-containing compound transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032239 , obo:GO_0051051 , obo:GO_0065007 .
obo:PHIPO_0001042 a rdfs:Class ;
rdfs:label "obsolete substance absent in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is too low to detect." .
obo:CL_4307012 a rdfs:Class ;
rdfs:label "CBX MLI Cdh22 Gaba molecular layer interneuron (Mmus)" ;
rdfs:comment "A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cdh1 (Mmus), Acvr1c (Mmus), Adamts15 (Mmus), Pax2 (Mmus). It is distinguished from other CB GABA cells by expression of Cdh1, Acvr1c, Adamts15, Pax2. It is GABAergic (inferred from expression of Gad1, Gad2, Slc32a1). These cells are located in the Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5192 CBX MLI Cdh22 Gaba_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4042035 , obo:CL_4300028 .
obo:UBERON_0003544 a rdfs:Class ;
rdfs:label "brain white matter" ;
rdfs:comment "The regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites." ;
rdfs:subClassOf obo:UBERON_0002316 .
obo:GO_0003343 a rdfs:Class ;
rdfs:label "septum transversum development" ;
rdfs:comment "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060485 .
obo:GO_0010763 a rdfs:Class ;
rdfs:label "positive regulation of fibroblast migration" ;
rdfs:comment "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." ;
rdfs:subClassOf obo:GO_0010762 , obo:GO_0030335 , obo:GO_0065007 .
obo:PHIPO_0000342 a rdfs:Class ;
rdfs:label "premature pathogen cell to cell migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism happens sooner than normal." ;
rdfs:subClassOf obo:PHIPO_0000334 .
obo:CL_0001012 a rdfs:Class ;
rdfs:label "CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor" ;
rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1110000)(PMID:19243617)." ;
rdfs:subClassOf obo:CL_0001060 , obo:CL_0011026 .
obo:CHEBI_36339 a rdfs:Class ;
rdfs:label "baryon" ;
rdfs:comment "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek βαρυσ (heavy)." ;
rdfs:subClassOf obo:CHEBI_36340 , obo:CHEBI_36344 .
obo:UBERON_0000078 a rdfs:Class ;
rdfs:label "mixed ectoderm/mesoderm/endoderm-derived structure" ;
rdfs:comment "An anatomical structure that develops from the ectoderm, mesoderm and endoderm." ;
rdfs:subClassOf obo:UBERON_0000061 , obo:UBERON_0000077 , obo:UBERON_0004121 .
obo:CHEBI_37838 a rdfs:Class ;
rdfs:label "carboacyl group" ;
rdfs:comment "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." ;
rdfs:subClassOf obo:CHEBI_22221 .
obo:PHIPO_0000948 a rdfs:Class ;
rdfs:label "mutualism absent"@en ;
rdfs:comment "A pathogen host interaction where the mutualism phenotype is normal (i.e. the same as wild-type), and the wild-type interaction does not exhibit mutualism." ;
rdfs:subClassOf obo:PHIPO_0000039 .
obo:CHEBI_33560 a rdfs:Class ;
rdfs:label "p-block element atom" ;
rdfs:comment "Any main group element atom belonging to the p-block of the periodic table." ;
rdfs:subClassOf obo:CHEBI_33318 .
obo:GO_0001825 a rdfs:Class ;
rdfs:label "blastocyst formation" ;
rdfs:comment "The initial formation of a blastocyst from a solid ball of cells known as a morula." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_1905079 a rdfs:Class ;
rdfs:label "regulation of cerebellar neuron development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cerebellar neuron development." ;
rdfs:subClassOf obo:GO_0045664 , obo:GO_0060284 , obo:GO_0065007 .
obo:GO_0031344 a rdfs:Class ;
rdfs:label "regulation of cell projection organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:PR_000001006 a rdfs:Class ;
rdfs:label "receptor-type tyrosine-protein phosphatase C" ;
rdfs:comment "A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0051027 a rdfs:Class ;
rdfs:label "DNA transport" ;
rdfs:comment "The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0050657 .
obo:UBERON_0005397 a rdfs:Class ;
rdfs:label "brain arachnoid mater" ;
rdfs:comment "An arachnoid mater that surrounds a brain." ;
rdfs:subClassOf obo:UBERON_0002362 , obo:UBERON_0003547 .
obo:UBERON_0003257 a rdfs:Class ;
rdfs:label "yolk sac endoderm" ;
rdfs:comment "The portion of the yolk sac that is derived from endoderm and lines the yolk sac." ;
rdfs:subClassOf obo:UBERON_0000478 , obo:UBERON_0000483 , obo:UBERON_0005292 , obo:UBERON_0005911 .
obo:CHEBI_38163 a rdfs:Class ;
rdfs:label "organic heterotetracyclic compound" ;
rdfs:subClassOf obo:CHEBI_38166 .
obo:CHEBI_64915 a rdfs:Class ;
rdfs:label "antiplasmodial drug" ;
rdfs:comment "An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria." ;
rdfs:subClassOf obo:CHEBI_35820 .
obo:GO_0048132 a rdfs:Class ;
rdfs:label "female germ-line stem cell asymmetric division" ;
rdfs:comment "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes." ;
rdfs:subClassOf obo:GO_0008356 , obo:GO_0098728 .
obo:GO_0090025 a rdfs:Class ;
rdfs:label "regulation of monocyte chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of monocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0002688 , obo:GO_0065007 , obo:GO_0071675 .
obo:CHEBI_24127 a rdfs:Class ;
rdfs:label "fungicide" ;
rdfs:comment "A substance used to destroy fungal pests." ;
rdfs:subClassOf obo:CHEBI_25944 , obo:CHEBI_35718 .
obo:GO_0071166 a rdfs:Class ;
rdfs:label "ribonucleoprotein complex localization" ;
rdfs:comment "Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell." ;
rdfs:subClassOf obo:GO_0051641 .
obo:CHEBI_23451 a rdfs:Class ;
rdfs:label "cyclitol" ;
rdfs:comment "A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom." ;
rdfs:subClassOf obo:CHEBI_26191 .
obo:GO_0150033 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to lysosome" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0150031 , obo:GO_1903828 .
obo:CHEBI_35915 a rdfs:Class ;
rdfs:label "sterol ester" ;
rdfs:comment "A steroid ester obtained by formal condensation of the carboxy group of any carboxylic acid with the 3-hydroxy group of a sterol." ;
rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_47880 .
obo:CHEBI_50845 a rdfs:Class ;
rdfs:label "doxycycline" ;
rdfs:comment "Tetracycline in which the 5β-hydrogen is replaced by a hydroxy group, while the 6α-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis." ;
rdfs:subClassOf obo:CHEBI_26895 .
obo:CHEBI_139588 a rdfs:Class ;
rdfs:label "alpha-hydroxy ketone" ;
rdfs:comment "A ketone containing a hydroxy group on the α-carbon relative to the C=O group." ;
rdfs:subClassOf obo:CHEBI_17087 , obo:CHEBI_33822 .
obo:UBERON_0002090 a rdfs:Class ;
rdfs:label "postcranial axial skeleton" ;
rdfs:comment "The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:GO_0042170 a rdfs:Class ;
rdfs:label "plastid membrane" ;
rdfs:comment "Any lipid bilayer that surrounds a plastid or is part of the plastid envelope. Primary plastids (in plants, green algae, red algae, and glaucophytes) are surrounded by two membranes; complex plastids derived from secondary endosymbiosis are surrounded by three or four membranes." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031090 .
obo:CHEBI_16646 a rdfs:Class ;
rdfs:label "carbohydrate" ;
rdfs:comment "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." ;
rdfs:subClassOf obo:CHEBI_78616 .
obo:GO_1904689 a rdfs:Class ;
rdfs:label "negative regulation of cytoplasmic translational initiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation." ;
rdfs:subClassOf obo:GO_0045947 , obo:GO_0065007 , obo:GO_1904688 .
obo:CHEBI_23953 a rdfs:Class ;
rdfs:label "erythromycins" ;
rdfs:subClassOf obo:CHEBI_25105 .
obo:GO_1903039 a rdfs:Class ;
rdfs:label "positive regulation of leukocyte cell-cell adhesion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion." ;
rdfs:subClassOf obo:GO_0022409 , obo:GO_0065007 , obo:GO_1903037 .
obo:PHIPO_0000483 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host interaction phenotype" ;
rdfs:comment "A pathogen host interaction phenotype which is normal (i.e. the same as wild-type)." .
obo:CHEBI_33551 a rdfs:Class ;
rdfs:label "organosulfonic acid" ;
rdfs:comment "An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon." ;
rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_33552 , obo:CHEBI_64709 .
obo:PHIPO_0000322 a rdfs:Class ;
rdfs:label "obsolete gain of effector of pathogenicity activation of host defense" ;
rdfs:comment "The pathogen effector entity has gained the ability to activate host defense." .
obo:PHIPO_0000584 a rdfs:Class ;
rdfs:label "resistance to brefeldin A"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to brefeldin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_38032 a rdfs:Class ;
rdfs:label "carbotricyclic compound" ;
rdfs:comment "A carbopolyclic compound comprising of three carbocyclic rings." ;
rdfs:subClassOf obo:CHEBI_35294 , obo:CHEBI_51959 .
obo:GO_0060173 a rdfs:Class ;
rdfs:label "limb development" ;
rdfs:comment "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin." ;
rdfs:subClassOf obo:GO_0048736 , obo:GO_0048856 .
obo:GO_0034103 a rdfs:Class ;
rdfs:label "regulation of tissue remodeling" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of tissue remodeling." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 .
obo:GO_0036035 a rdfs:Class ;
rdfs:label "osteoclast development" ;
rdfs:comment "The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue." ;
rdfs:subClassOf obo:GO_0048468 , obo:GO_0061515 , obo:GO_0098751 .
obo:CHEBI_36856 a rdfs:Class ;
rdfs:label "hydrogen isocyanide" ;
rdfs:subClassOf obo:CHEBI_33405 .
obo:CHEBI_60690 a rdfs:Class ;
rdfs:label "nitrogen-containing fatty acid" ;
rdfs:comment "Any fatty acid containing nitrogen as either a substituent or a replacement for a methylene carbon." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:GO_0044057 a rdfs:Class ;
rdfs:label "regulation of system process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 .
obo:GO_0044550 a rdfs:Class ;
rdfs:label "secondary metabolite biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0019748 .
obo:UBERON_0005478 a rdfs:Class ;
rdfs:label "sulcus limitans of neural tube" ;
rdfs:comment "A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]." ;
rdfs:subClassOf obo:UBERON_0006846 .
obo:UBERON_0007304 a rdfs:Class ;
rdfs:label "appendage vasculature" ;
rdfs:comment "A vasculature that is part of a limb/fin." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:GO_0001664 a rdfs:Class ;
rdfs:label "G protein-coupled receptor binding" ;
rdfs:comment "Binding to a G protein-coupled receptor." ;
rdfs:subClassOf obo:GO_0005102 .
obo:UBERON_0001572 a rdfs:Class ;
rdfs:label "hyoglossus muscle" ;
rdfs:comment "A muscle that attaches to the hyopid bone and to the tongue and is innervated by cranial nerve XII." ;
rdfs:subClassOf obo:UBERON_0001575 , obo:UBERON_0014892 .
obo:GO_0002703 a rdfs:Class ;
rdfs:label "regulation of leukocyte mediated immunity" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity." ;
rdfs:subClassOf obo:GO_0002697 , obo:GO_0065007 .
obo:UBERON_0003390 a rdfs:Class ;
rdfs:label "mesothelium of pleural cavity" ;
rdfs:comment "A mesothelium that is part of a pleural cavity [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001136 .
obo:GO_0007369 a rdfs:Class ;
rdfs:label "gastrulation" ;
rdfs:comment "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." ;
rdfs:subClassOf obo:GO_0048598 .
obo:CHEBI_83056 a rdfs:Class ;
rdfs:label "Daphnia magna metabolite" ;
rdfs:comment "A Daphnia metabolite produced by the species Daphnia magna." ;
rdfs:subClassOf obo:CHEBI_83057 .
obo:GO_0090166 a rdfs:Class ;
rdfs:label "Golgi disassembly" ;
rdfs:comment "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance." ;
rdfs:subClassOf obo:GO_0007030 , obo:GO_0022411 , obo:GO_1903008 .
obo:CHEBI_38922 a rdfs:Class ;
rdfs:label "dibenzofurans" ;
rdfs:comment "Any organic heterotricyclic compound based on a dibenzofuran skeleton and its substituted derivatives thereof." ;
rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38104 .
obo:CL_0000131 a rdfs:Class ;
rdfs:label "gut endothelial cell" ;
rdfs:comment "An endothelial cell that lines the blood and lymphatic vessels of the digestive tract. This cell forms the gut–vascular barrier (GVB) through tight junctions and crosstalk with pericytes and enteric glial cells, regulating the passage of nutrients and immune cells while restricting microbial translocation into the bloodstream." ;
rdfs:subClassOf obo:CL_0000115 .
obo:GO_0032289 a rdfs:Class ;
rdfs:label "central nervous system myelin formation" ;
rdfs:comment "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system." ;
rdfs:subClassOf obo:GO_0032288 .
obo:GO_0050805 a rdfs:Class ;
rdfs:label "negative regulation of synaptic transmission" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." ;
rdfs:subClassOf obo:GO_0010648 , obo:GO_0023057 , obo:GO_0050804 , obo:GO_0065007 .
obo:GO_0043025 a rdfs:Class ;
rdfs:label "neuronal cell body" ;
rdfs:comment "The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites." ;
rdfs:subClassOf obo:GO_0044297 .
obo:UBERON_0001418 a rdfs:Class ;
rdfs:label "skin of thorax" ;
rdfs:comment "A zone of skin that is part of a thorax [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0001085 .
obo:GO_0009847 a rdfs:Class ;
rdfs:label "spore germination" ;
rdfs:comment "The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall)." ;
rdfs:subClassOf obo:GO_0048869 .
obo:PHIPO_0001234 a rdfs:Class ;
rdfs:label "increased hyphal growth"@en ;
rdfs:comment "An individual organism growth phenotype in which the growth of hyphae is increased." ;
rdfs:subClassOf obo:PHIPO_0001215 .
obo:PHIPO_0001453 a rdfs:Class ;
rdfs:label "BAX-induced cell death present"@en ;
rdfs:comment "A single species phenotype in which the expression or activity of the pro-apoptotic protein BAX leads to observable cell death." ;
rdfs:subClassOf obo:PHIPO_0000446 .
obo:PR_P50220 a rdfs:Class ;
rdfs:label "homeobox protein Nkx-2.1 (mouse)" ;
rdfs:comment "A homeobox protein Nkx-2.1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000011241 , obo:PR_000029032 .
obo:PHIPO_0000449 a rdfs:Class ;
rdfs:label "abnormal pathogen asexual reproduction within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host where the pathogen asexual reproduction process, in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is abnormal (GO:0019954)." ;
rdfs:subClassOf obo:PHIPO_0000469 .
obo:UBERON_0003511 a rdfs:Class ;
rdfs:label "iris blood vessel" ;
rdfs:comment "A blood vessel that is part of a iris [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003496 .
obo:PHIPO_0000791 a rdfs:Class ;
rdfs:label "sensitive to nitrofurantoin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to nitrofurantoin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_2000406 a rdfs:Class ;
rdfs:label "positive regulation of T cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of T cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000403 , obo:GO_2000404 .
obo:GO_0045202 a rdfs:Class ;
rdfs:label "synapse" ;
rdfs:comment "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." ;
rdfs:subClassOf obo:GO_0030054 .
obo:UBERON_0034706 a rdfs:Class ;
rdfs:label "proliferating neuroepithelium" ;
rdfs:comment "An epithelium that is undergoing proliferation to provide large numbers of neuronal cells." ;
rdfs:subClassOf obo:UBERON_0034705 .
obo:GO_0050708 a rdfs:Class ;
rdfs:label "regulation of protein secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." ;
rdfs:subClassOf obo:GO_0051223 , obo:GO_0065007 , obo:GO_1903530 .
obo:UBERON_0000481 a rdfs:Class ;
rdfs:label "multi-tissue structure" ;
rdfs:comment "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:GO_0046660 a rdfs:Class ;
rdfs:label "female sex differentiation" ;
rdfs:comment "The establishment of the sex of a female organism by physical differentiation." ;
rdfs:subClassOf obo:GO_0007548 .
obo:CHEBI_59792 a rdfs:Class ;
rdfs:label "thioacetal" ;
rdfs:comment "The sulfur analogue of 'acetal'. The term includes monothioacetals having the structure R2C(OR')(SR') (subclass monothioketals, R ≠ H); and dithioacetals having the structure R2C(SR')2 (subclass dithioketals, R ≠ H, R' ≠ H)." ;
rdfs:subClassOf obo:CHEBI_33261 .
obo:UBERON_0005501 a rdfs:Class ;
rdfs:label "rhombomere lateral wall" ;
rdfs:comment "A neural tube lateral wall that is part of a rhombomere." ;
rdfs:subClassOf obo:UBERON_0005496 .
obo:CHEBI_26094 a rdfs:Class ;
rdfs:label "benzenedicarboxylic acid" ;
rdfs:comment "A member of the class of benzoic acids in that consists of benzene substituted by two carboxy groups (A closed class)." ;
rdfs:subClassOf obo:CHEBI_22723 , obo:CHEBI_35692 .
obo:GO_2000278 a rdfs:Class ;
rdfs:label "regulation of DNA biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of DNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010556 , obo:GO_0051052 , obo:GO_0065007 .
obo:PHIPO_0001013 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction polysaccharide localization" ;
rdfs:comment "A pathogen host interaction phenotype in which the localization of a polysaccharide in a pathogen or host cell is abnormal. This includes any process in which a polysaccharide is transported to, or maintained in, a specific location. (GO:0033037)." .
obo:CL_0000228 a rdfs:Class ;
rdfs:label "multinucleate cell" ;
rdfs:comment "A cell with more than one nucleus." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 , obo:CL_0002242 .
obo:PHIPO_0001431 a rdfs:Class ;
rdfs:label "sensitive to ipconazole" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ipconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0040018 a rdfs:Class ;
rdfs:label "positive regulation of multicellular organism growth" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size." ;
rdfs:subClassOf obo:GO_0040014 , obo:GO_0048639 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0086029 a rdfs:Class ;
rdfs:label "Purkinje myocyte to ventricular cardiac muscle cell signaling" ;
rdfs:comment "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell." ;
rdfs:subClassOf obo:GO_0007267 , obo:GO_0086068 .
obo:CL_1000491 a rdfs:Class ;
rdfs:label "mesothelial cell of pleura" ;
rdfs:comment "A mesothelial cell that is part of the pleura." ;
rdfs:subClassOf obo:CL_0000077 .
obo:CHEBI_64767 a rdfs:Class ;
rdfs:label "anionic group" ;
rdfs:comment "A group that carries an overall negative charge." ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:GO_1904491 a rdfs:Class ;
rdfs:label "protein localization to ciliary transition zone" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0061512 .
obo:UBERON_0010096 a rdfs:Class ;
rdfs:label "future myelencephalon" ;
rdfs:comment "A developing anatomical structure that has the potential to develop into a myelencephalon." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:UBERON_0003383 a rdfs:Class ;
rdfs:label "cardiac muscle tissue of interventricular septum" ;
rdfs:comment "A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001133 , obo:UBERON_0004492 , obo:UBERON_0004667 .
obo:PR_P15655 a rdfs:Class ;
rdfs:label "fibroblast growth factor 2 (mouse)" ;
rdfs:comment "A fibroblast growth factor 2 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000007489 , obo:PR_000029032 .
obo:GO_0010171 a rdfs:Class ;
rdfs:label "body morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the soma are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CL_4042017 a rdfs:Class ;
rdfs:label "alpha1-tanycyte"@en ;
rdfs:comment "The dorsal-most tanycyte type of the third venticle. These cells projects into the ventromedial or dorsomedial nucleus of the hypothalamus. This type of tanycyte extends its protrusions close to parenchymal neurons without contacting blood vessels. It expresses the glial marker S-100β." ;
rdfs:subClassOf obo:CL_0002085 .
obo:CHEBI_15904 a rdfs:Class ;
rdfs:label "long-chain fatty acid" ;
rdfs:comment "A fatty acid with a chain length ranging from C13 to C22." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:GO_0097386 a rdfs:Class ;
rdfs:label "glial cell projection" ;
rdfs:comment "A prolongation or process extending from a glial cell." ;
rdfs:subClassOf obo:GO_0120025 .
obo:CHEBI_76738 a rdfs:Class ;
rdfs:label "EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*)." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:GO_1904830 a rdfs:Class ;
rdfs:label "negative regulation of aortic smooth muscle cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904829 , obo:GO_1905064 .
obo:CHEBI_52557 a rdfs:Class ;
rdfs:label "tetracyclic diterpenoid" ;
rdfs:comment "A diterpenoid with a tetracyclic skeleton." ;
rdfs:subClassOf obo:CHEBI_23849 .
obo:GO_0072697 a rdfs:Class ;
rdfs:label "protein localization to cell cortex" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, the cell cortex." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_1990778 .
obo:GO_0051445 a rdfs:Class ;
rdfs:label "regulation of meiotic cell cycle" ;
rdfs:comment "Any process that modulates the rate or extent of progression through the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0051726 , obo:GO_0065007 , obo:GO_2000241 .
obo:GO_0001754 a rdfs:Class ;
rdfs:label "eye photoreceptor cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0046530 .
obo:NCBITaxon_88770 a rdfs:Class ;
rdfs:label "Panarthropoda" ;
rdfs:subClassOf obo:NCBITaxon_1206794 .
obo:CHEBI_33459 a rdfs:Class ;
rdfs:label "pnictogen oxoanion" ;
rdfs:subClassOf obo:CHEBI_33302 , obo:CHEBI_35406 .
obo:PHIPO_0000576 a rdfs:Class ;
rdfs:label "resistance to strobilurin A"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to strobilurin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0042221 a rdfs:Class ;
rdfs:label "response to chemical" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ;
rdfs:subClassOf obo:GO_0050896 .
obo:GO_1904983 a rdfs:Class ;
rdfs:label "glycine import into mitochondrion" ;
rdfs:comment "The process in which glycine is transported from the cytosol into the mitochondrial matrix." ;
rdfs:subClassOf obo:GO_0003333 , obo:GO_0015816 , obo:GO_0046907 , obo:GO_0170036 , obo:GO_1905039 .
obo:UBERON_0034969 a rdfs:Class ;
rdfs:label "epithelial layer of duct" ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003914 .
obo:PHIPO_0001111 a rdfs:Class ;
rdfs:label "obsolete pathogen-induced increase in host pH" ;
rdfs:comment "A pathogen host interaction phenotype where the pathogen induces a pH increase within the host cell or cellular component." .
obo:CL_4023072 a rdfs:Class ;
rdfs:label "brain vascular cell" ;
rdfs:comment "A cell that is part of the brain vasculature." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0002319 .
obo:GO_0006921 a rdfs:Class ;
rdfs:label "cellular component disassembly involved in execution phase of apoptosis" ;
rdfs:comment "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." ;
rdfs:subClassOf obo:GO_0022411 .
obo:UBERON_0000086 a rdfs:Class ;
rdfs:label "zona pellucida" ;
rdfs:comment "A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes." ;
rdfs:subClassOf obo:UBERON_0005764 .
obo:GO_1902340 a rdfs:Class ;
rdfs:label "negative regulation of chromosome condensation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation." ;
rdfs:subClassOf obo:GO_0060623 , obo:GO_0065007 , obo:GO_2001251 .
obo:GO_0032273 a rdfs:Class ;
rdfs:label "positive regulation of protein polymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." ;
rdfs:subClassOf obo:GO_0031334 , obo:GO_0032271 , obo:GO_0065007 .
obo:GO_2001028 a rdfs:Class ;
rdfs:label "positive regulation of endothelial cell chemotaxis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis." ;
rdfs:subClassOf obo:GO_0010595 , obo:GO_0050921 , obo:GO_0065007 , obo:GO_2001026 .
obo:CL_0002377 a rdfs:Class ;
rdfs:label "immature Schwann cell" ;
rdfs:comment "A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons." ;
rdfs:subClassOf obo:CL_0002573 .
obo:CHEBI_87036 a rdfs:Class ;
rdfs:label "benzimidazole fungicide" ;
rdfs:comment "Compounds that contain a benzimidazole moiety as a key feature of their structure and which have been used as fungicides." ;
rdfs:subClassOf obo:CHEBI_22715 .
obo:UBERON_0008947 a rdfs:Class ;
rdfs:label "respiratory primordium" ;
rdfs:subClassOf obo:UBERON_0001048 .
obo:GO_1903624 a rdfs:Class ;
rdfs:label "regulation of DNA catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of DNA catabolic process." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0051052 , obo:GO_0065007 .
obo:GO_1904350 a rdfs:Class ;
rdfs:label "regulation of protein catabolic process in the vacuole" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole." ;
rdfs:subClassOf obo:GO_0042176 , obo:GO_0065007 .
obo:GO_0043086 a rdfs:Class ;
rdfs:label "negative regulation of catalytic activity" ;
rdfs:comment "Any process that stops or reduces the activity of an enzyme." ;
rdfs:subClassOf obo:GO_0044092 , obo:GO_0050790 , obo:GO_0065007 .
obo:GO_0110077 a rdfs:Class ;
rdfs:label "vesicle-mediated intercellular transport" ;
rdfs:comment "A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane." ;
rdfs:subClassOf obo:GO_0010496 , obo:GO_0016192 .
obo:GO_0042415 a rdfs:Class ;
rdfs:label "norepinephrine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." ;
rdfs:subClassOf obo:GO_0006584 , obo:GO_0008152 .
obo:CL_4030047 a rdfs:Class ;
rdfs:label "matrix D2 medium spiny neuron" ;
rdfs:comment "A DRD2-expressing medium spiny neuron that is part of a matrix compartment of dorsal striatum." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_4023029 .
obo:UBERON_0007794 a rdfs:Class ;
rdfs:label "secretion of serous gland" ;
rdfs:comment "Any fluid produced by a serous gland." ;
rdfs:subClassOf obo:UBERON_0000456 , obo:UBERON_0006314 .
obo:GO_0099171 a rdfs:Class ;
rdfs:label "presynaptic modulation of chemical synaptic transmission" ;
rdfs:comment "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." ;
rdfs:subClassOf obo:GO_0050804 .
obo:GO_0051644 a rdfs:Class ;
rdfs:label "plastid localization" ;
rdfs:comment "Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051640 .
obo:CHEBI_22494 a rdfs:Class ;
rdfs:label "aminobenzoate" ;
rdfs:subClassOf obo:CHEBI_22718 .
obo:GO_1900115 a rdfs:Class ;
rdfs:label "extracellular regulation of signal transduction" ;
rdfs:comment "Any regulation of signal transduction that takes place in the extracellular region." ;
rdfs:subClassOf obo:GO_0009966 .
obo:GO_0003382 a rdfs:Class ;
rdfs:label "epithelial cell morphogenesis" ;
rdfs:comment "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state." ;
rdfs:subClassOf obo:GO_0000902 , obo:GO_0009653 .
obo:GO_0043249 a rdfs:Class ;
rdfs:label "erythrocyte maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0048469 .
obo:CHEBI_65259 a rdfs:Class ;
rdfs:label "GABA antagonist" ;
rdfs:comment "A compound that inhibits the action of γ-aminobutyric acid." ;
rdfs:subClassOf obo:CHEBI_48706 , obo:CHEBI_51374 .
obo:UBERON_3010200 a rdfs:Class ;
rdfs:label "vasculature of respiratory integument" ;
rdfs:comment "Blood vessels in respiratory skin." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003504 .
obo:PHIPO_0001143 a rdfs:Class ;
rdfs:label "abolished pathogen protein localization to host chloroplast"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the localization of a pathogen protein to the host chloroplast is abolished (i.e.the protein was localized to the host chloroplast and now is not)." ;
rdfs:subClassOf obo:PHIPO_0000246 .
obo:GO_1905142 a rdfs:Class ;
rdfs:label "positive regulation of apical ectodermal ridge formation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1905140 .
obo:GO_0040029 a rdfs:Class ;
rdfs:label "epigenetic regulation of gene expression" ;
rdfs:comment "A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal." ;
rdfs:subClassOf obo:GO_0006338 , obo:GO_0010468 .
obo:UBERON_0015179 a rdfs:Class ;
rdfs:label "somite boundary epithelium" ;
rdfs:comment "Epithelium located in the intersomitic region." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:PR_P13595 a rdfs:Class ;
rdfs:label "neural cell adhesion molecule 1 (mouse)" ;
rdfs:comment "A neural cell adhesion molecule 1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001024 , obo:PR_000029032 .
obo:GO_0002264 a rdfs:Class ;
rdfs:label "endothelial cell activation involved in immune response" ;
rdfs:comment "A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0002263 , obo:GO_0042118 .
obo:NCBITaxon_2759 a rdfs:Class ;
rdfs:label "Eukaryota" ;
rdfs:subClassOf obo:NCBITaxon_131567 .
obo:CHEBI_77932 a rdfs:Class ;
rdfs:label "tetracycline zwitterion" ;
rdfs:comment "A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of tetracycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." ;
rdfs:subClassOf obo:CHEBI_144644 , obo:CHEBI_27369 .
obo:CL_0000008 a rdfs:Class ;
rdfs:label "migratory cranial neural crest cell" ;
rdfs:comment "Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination." ;
rdfs:subClassOf obo:CL_0000333 .
obo:CL_0002553 a rdfs:Class ;
rdfs:label "fibroblast of lung" ;
rdfs:comment "A fibroblast that is part of lung." ;
rdfs:subClassOf obo:CL_0000057 .
obo:GO_0032940 a rdfs:Class ;
rdfs:label "secretion by cell" ;
rdfs:comment "The controlled release of a substance by a cell." ;
rdfs:subClassOf obo:GO_0046903 , obo:GO_0140352 .
obo:GO_0016907 a rdfs:Class ;
rdfs:label "G protein-coupled acetylcholine receptor activity" ;
rdfs:comment "Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." ;
rdfs:subClassOf obo:GO_0004930 , obo:GO_0008227 , obo:GO_0015464 , obo:GO_0099528 .
obo:GO_0051236 a rdfs:Class ;
rdfs:label "establishment of RNA localization" ;
rdfs:comment "The directed movement of RNA to a specific location." ;
rdfs:subClassOf obo:GO_0051234 .
obo:GO_0022804 a rdfs:Class ;
rdfs:label "active transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." ;
rdfs:subClassOf obo:GO_0022857 .
obo:CHEBI_51402 a rdfs:Class ;
rdfs:label "phenylenediamine" ;
rdfs:comment "A benzene substituted with two amino groups." ;
rdfs:subClassOf obo:CHEBI_33860 , obo:CHEBI_35410 .
obo:CL_0002005 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell" ;
rdfs:comment "A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative." ;
rdfs:subClassOf obo:CL_0000050 .
obo:GO_0034486 a rdfs:Class ;
rdfs:label "vacuolar transmembrane transport" ;
rdfs:comment "The process in which a solute is transported from one side of the vacuolar membrane to the other." ;
rdfs:subClassOf obo:GO_0055085 .
obo:UBERON_0005638 a rdfs:Class ;
rdfs:label "anterior chamber epithelium" ;
rdfs:comment "An epithelium that is part of a anterior chamber of eyeball." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0015808 .
obo:GO_0060219 a rdfs:Class ;
rdfs:label "camera-type eye photoreceptor cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye." ;
rdfs:subClassOf obo:GO_0001754 , obo:GO_0030154 .
obo:GO_0021814 a rdfs:Class ;
rdfs:label "cell motility involved in cerebral cortex radial glia guided migration" ;
rdfs:comment "The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration." ;
rdfs:subClassOf obo:GO_0048870 .
obo:GO_0033278 a rdfs:Class ;
rdfs:label "cell proliferation in midbrain" ;
rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0061351 .
obo:PHIPO_0001063 a rdfs:Class ;
rdfs:label "RNA absent from cell"@en ;
rdfs:comment "A single species cell phenotype in which the amount of RNA measured in a cell is too low to detect. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." ;
rdfs:subClassOf obo:PHIPO_0001034 , obo:PHIPO_0001060 .
obo:CL_0000067 a rdfs:Class ;
rdfs:label "ciliated epithelial cell" ;
rdfs:comment "An epithelial cell that has a cilia." ;
rdfs:subClassOf obo:CL_0000064 , obo:CL_0000066 .
obo:CL_0002632 a rdfs:Class ;
rdfs:label "epithelial cell of lower respiratory tract" ;
rdfs:comment "Any epithelial cell that is part of some lower respiratory tract epithelium." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002368 .
obo:CHEBI_131604 a rdfs:Class ;
rdfs:label "Mycoplasma genitalium metabolite" ;
rdfs:comment "Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium." ;
rdfs:subClassOf obo:CHEBI_76969 .
obo:CHEBI_35443 a rdfs:Class ;
rdfs:label "anthelminthic drug" ;
rdfs:comment "Substance intended to kill parasitic worms (helminths)." ;
rdfs:subClassOf obo:CHEBI_35442 .
obo:CHEBI_28084 a rdfs:Class ;
rdfs:label "3-(carbamoyloxymethyl)cephalosporin" ;
rdfs:subClassOf obo:CHEBI_23066 .
obo:CHEBI_78696 a rdfs:Class ;
rdfs:label "cercosporamide" ;
rdfs:comment "A member of the class of dibenzofurans that is a potent broad spectrum antifungal agent isolated from the fungus Cercosporidium henningsii." ;
rdfs:subClassOf obo:CHEBI_26195 , obo:CHEBI_29347 , obo:CHEBI_38922 , obo:CHEBI_51867 .
obo:CHEBI_46577 a rdfs:Class ;
rdfs:label "dextrofloxacin" ;
rdfs:comment "The (R)-enantiomer of ofloxacin." ;
rdfs:subClassOf obo:CHEBI_194135 , obo:CHEBI_86324 , obo:CHEBI_87211 .
obo:GO_0098960 a rdfs:Class ;
rdfs:label "postsynaptic neurotransmitter receptor activity" ;
rdfs:comment "Neurotransmitter receptor activity occurring in the postsynaptic membrane during synaptic transmission." ;
rdfs:subClassOf obo:GO_0030594 .
obo:PATO_0001548 a rdfs:Class ;
rdfs:label "quality of a liquid" ;
rdfs:comment "A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape." ;
rdfs:subClassOf obo:PATO_0002198 .
obo:GO_0044566 a rdfs:Class ;
rdfs:label "chondrocyte activation" ;
rdfs:comment "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage." ;
rdfs:subClassOf obo:GO_0001775 .
obo:UBERON_0003443 a rdfs:Class ;
rdfs:label "thoracic cavity nerve" ;
rdfs:comment "A nerve that is located in a thoracic cavity [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:UBERON_0002285 a rdfs:Class ;
rdfs:label "telencephalic ventricle" ;
rdfs:comment "A brain ventricle that is part of a telencephalon. In mammals and species with an evaginated telencephalon, this is one of a pair of lateral structures, one in each hemisphere." ;
rdfs:subClassOf obo:UBERON_0004086 .
obo:GO_0021879 a rdfs:Class ;
rdfs:label "forebrain neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain." ;
rdfs:subClassOf obo:GO_0021953 , obo:GO_0030154 .
obo:GO_0033365 a rdfs:Class ;
rdfs:label "protein localization to organelle" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within an organelle." ;
rdfs:subClassOf obo:GO_0008104 .
obo:CHEBI_24780 a rdfs:Class ;
rdfs:label "imidazoles" ;
rdfs:comment "A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." ;
rdfs:subClassOf obo:CHEBI_23677 .
obo:GO_0099081 a rdfs:Class ;
rdfs:label "supramolecular polymer" ;
rdfs:comment "A polymeric supramolecular structure." ;
rdfs:subClassOf obo:GO_0099080 .
obo:CHEBI_50695 a rdfs:Class ;
rdfs:label "monobactam" ;
rdfs:comment "Monocyclic, bacterially produced or semisynthetic beta-lactam antibiotic. It lacks the double ring construction of the traditional beta-lactam antibiotics and can be easily synthesized." ;
rdfs:subClassOf obo:CHEBI_27933 .
obo:GO_0003151 a rdfs:Class ;
rdfs:label "outflow tract morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_60809 a rdfs:Class ;
rdfs:label "adjuvant" ;
rdfs:comment "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself." ;
rdfs:subClassOf obo:CHEBI_52217 .
obo:GO_1904398 a rdfs:Class ;
rdfs:label "positive regulation of neuromuscular junction development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuromuscular junction development." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1904396 .
obo:GO_0007420 a rdfs:Class ;
rdfs:label "brain development" ;
rdfs:comment "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:GO_0010718 a rdfs:Class ;
rdfs:label "positive regulation of epithelial to mesenchymal transition" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." ;
rdfs:subClassOf obo:GO_0010717 , obo:GO_0045597 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0002281 a rdfs:Class ;
rdfs:label "macrophage activation involved in immune response" ;
rdfs:comment "A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0002366 , obo:GO_0042116 .
obo:GO_0007159 a rdfs:Class ;
rdfs:label "leukocyte cell-cell adhesion" ;
rdfs:comment "The attachment of a leukocyte to another cell via adhesion molecules." ;
rdfs:subClassOf obo:GO_0098609 .
obo:GO_0051965 a rdfs:Class ;
rdfs:label "positive regulation of synapse assembly" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ;
rdfs:subClassOf obo:GO_0051962 , obo:GO_0051963 , obo:GO_0065007 , obo:GO_1901890 .
obo:UBERON_0007143 a rdfs:Class ;
rdfs:label "right internal carotid artery" ;
rdfs:comment "An internal carotid artery that branching_part_of a right common carotid artery plus branches." ;
rdfs:subClassOf obo:UBERON_0001532 .
obo:UBERON_0000009 a rdfs:Class ;
rdfs:label "submucosa" ;
rdfs:comment "A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:CHEBI_48080 a rdfs:Class ;
rdfs:label "brefeldin A" ;
rdfs:comment "A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity." ;
rdfs:subClassOf obo:CHEBI_25105 .
obo:GO_0031333 a rdfs:Class ;
rdfs:label "negative regulation of protein-containing complex assembly" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." ;
rdfs:subClassOf obo:GO_0043254 , obo:GO_0051129 , obo:GO_0065007 .
obo:UBERON_0003560 a rdfs:Class ;
rdfs:label "spinal cord arachnoid mater" ;
rdfs:comment "An arachnoid mater that is part of a spinal cord [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002362 , obo:UBERON_0003292 .
obo:CHEBI_88061 a rdfs:Class ;
rdfs:label "polyamine" ;
rdfs:comment "Any organic amino compound that contains two or more amino groups." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:PATO_0045088 a rdfs:Class ;
rdfs:label "normal sensitivity of a process" ;
rdfs:comment "A sensitivity of a process which is relatively normal." ;
rdfs:subClassOf obo:PATO_0001457 , obo:PATO_0045073 .
obo:UBERON_0003967 a rdfs:Class ;
rdfs:label "cutaneous elastic tissue" ;
rdfs:comment "The slender connective tissue fiber in the extracellular matrix of skin tissue that is composed of microfibrils and amorphous elastin and is characterized by great elasticity." ;
rdfs:subClassOf obo:UBERON_0002521 .
obo:GO_0022617 a rdfs:Class ;
rdfs:label "extracellular matrix disassembly" ;
rdfs:comment "A process that results in the breakdown of the extracellular matrix." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0030198 .
obo:CHEBI_38496 a rdfs:Class ;
rdfs:label "electron-transport chain inhibitor" ;
rdfs:subClassOf obo:CHEBI_76932 .
obo:PHIPO_0000311 a rdfs:Class ;
rdfs:label "obsolete effector of virulence phenotype" ;
rdfs:comment "(gene for gene relationships) or defined from the phenotype described in the published study. The pathogen has the ability to cause infectious disease dependent upon the gene for gene relationship between the pathogen and host genotype." .
obo:GO_0090069 a rdfs:Class ;
rdfs:label "regulation of ribosome biogenesis" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." ;
rdfs:subClassOf obo:GO_0044087 , obo:GO_0065007 .
obo:PHIPO_0001122 a rdfs:Class ;
rdfs:label "decreased number of sexual sporulation structures"@en ;
rdfs:comment "A single species reproductive phenotype in which the frequency of occurrence of sexual sporulation structures is fewer than normal." ;
rdfs:subClassOf obo:PHIPO_0001121 .
obo:UBERON_0015757 a rdfs:Class ;
rdfs:label "heterogeneous tissue" ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:PHIPO_0000565 a rdfs:Class ;
rdfs:label "resistance to cefixime"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cefixime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0051052 a rdfs:Class ;
rdfs:label "regulation of DNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." ;
rdfs:subClassOf obo:GO_0019219 , obo:GO_0060255 , obo:GO_0065007 .
obo:GO_0045787 a rdfs:Class ;
rdfs:label "positive regulation of cell cycle" ;
rdfs:comment "Any process that activates or increases the rate or extent of progression through the cell cycle." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0051726 , obo:GO_0065007 .
obo:CL_4023054 a rdfs:Class ;
rdfs:label "mesothelial fibroblast" ;
rdfs:comment "A mesothelial cell that has undergone mesothelial-to-mesenchymal transition (MMT) to become a fibroblast cell." ;
rdfs:subClassOf obo:CL_0000057 .
obo:CL_0020010 a rdfs:Class ;
rdfs:label "arkypallidal neuron" ;
rdfs:comment "A GABAergic projection neuron located in the external segment of the globus pallidus (GPe) and defined by its exclusive projection to the dorsal striatum rather than to the subthalamic nucleus or basal ganglia output nuclei. In rodents and primates, it is characterized molecularly by expression of FOXP2, MEIS2, and NPAS1, and lacks expression of canonical pallidal markers NKX2-1 and LHX6 (Dodson et al., 2015; Abdi et al., 2015; Courtney et al., 2023). This neuron is GABAergic (GAD1/2⁺, SLC32A1/VGAT⁺) and typically PV⁻, forming the transcriptionally and developmentally LGE-derived subclass of GPe neurons (Dodson et al., 2015; Mallet et al., 2012)." ;
rdfs:subClassOf obo:CL_0000617 , obo:CL_0012001 , obo:CL_4023035 .
obo:CL_0019001 a rdfs:Class ;
rdfs:label "tracheobronchial serous cell"@en ;
rdfs:comment "Any serous secreting cell that is part of the tracheobronchial epithelium." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000313 .
obo:UBERON_0001803 a rdfs:Class ;
rdfs:label "epithelium of lens" ;
rdfs:comment "A layer of epithelial cells that is part of the eye." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0000484 , obo:UBERON_0015808 .
obo:UBERON_0003824 a rdfs:Class ;
rdfs:label "nerve of thoracic segment" ;
rdfs:comment "A nerve that is part of a thorax [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001021 , obo:UBERON_0003439 .
obo:PHIPO_0001193 a rdfs:Class ;
rdfs:label "increased level of host defense-induced reactive oxygen species"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host produced reactive oxygen species (ROS), often associated with an oxidative burst response during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0000924 .
obo:GO_0072595 a rdfs:Class ;
rdfs:label "maintenance of protein localization in organelle" ;
rdfs:comment "Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." ;
rdfs:subClassOf obo:GO_0032507 , obo:GO_0045185 .
obo:GO_0048744 a rdfs:Class ;
rdfs:label "negative regulation of skeletal muscle fiber development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0048742 , obo:GO_0051154 , obo:GO_0065007 .
obo:UBERON_0001981 a rdfs:Class ;
rdfs:label "blood vessel" ;
rdfs:comment "A vessel through which blood circulates in the body." ;
rdfs:subClassOf obo:UBERON_0000055 .
obo:GO_0000957 a rdfs:Class ;
rdfs:label "mitochondrial RNA catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ;
rdfs:subClassOf obo:GO_0000959 , obo:GO_0006401 .
obo:GO_1903350 a rdfs:Class ;
rdfs:label "response to dopamine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_0071869 .
obo:GO_0048849 a rdfs:Class ;
rdfs:label "neurohypophysis formation" ;
rdfs:comment "The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PHIPO_0000384 a rdfs:Class ;
rdfs:label "resistance to thiophanate methyl"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to thiophanate methyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0030428 a rdfs:Class ;
rdfs:label "cell septum" ;
rdfs:comment "A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells." ;
rdfs:subClassOf obo:GO_0110165 .
obo:PHIPO_0000115 a rdfs:Class ;
rdfs:label "decreased pathogen penetration across the barrier"@en ;
rdfs:comment "A single species pathogen penetration phenotype in which the frequency of occurrence of pathogen penetration of a given experimental substance/membrane is decreased" ;
rdfs:subClassOf obo:PHIPO_0000024 .
obo:UBERON_0007100 a rdfs:Class ;
rdfs:label "primary circulatory organ" ;
rdfs:comment "A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]." ;
rdfs:subClassOf obo:UBERON_0015228 .
obo:GO_0031090 a rdfs:Class ;
rdfs:label "organelle membrane" ;
rdfs:comment "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." ;
rdfs:subClassOf obo:GO_0016020 .
obo:CHEBI_36389 a rdfs:Class ;
rdfs:label "saturated organic heteromonocyclic parent" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_36388 .
obo:CHEBI_136859 a rdfs:Class ;
rdfs:label "pro-agent" ;
rdfs:comment "A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_0046112 a rdfs:Class ;
rdfs:label "nucleobase biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0009112 .
obo:PHIPO_0000427 a rdfs:Class ;
rdfs:label "obsolete pathogen chitin binding to host chitinase present" ;
rdfs:comment "A molecular function phenotype in which the binding of pathogen chitin to host chitinase is present." .
obo:GO_0060688 a rdfs:Class ;
rdfs:label "regulation of morphogenesis of a branching structure" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0051239 , obo:GO_0065007 .
obo:PR_000036194 a rdfs:Class ;
rdfs:label "eukaryotic protein" ;
rdfs:comment "A protein that is encoded in the genome of some Eukaryota." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_35107 a rdfs:Class ;
rdfs:label "azane" ;
rdfs:comment "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." ;
rdfs:subClassOf obo:CHEBI_35106 .
obo:CHEBI_46024 a rdfs:Class ;
rdfs:label "trichostatin A" ;
rdfs:subClassOf obo:CHEBI_24650 , obo:CHEBI_39146 , obo:CHEBI_86478 .
obo:PHIPO_0000261 a rdfs:Class ;
rdfs:label "abnormal endocytosis"@en ;
rdfs:comment "A single organism cellular process phenotype in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." ;
rdfs:subClassOf obo:PHIPO_0000257 , obo:PHIPO_0000929 .
obo:CL_0000451 a rdfs:Class ;
rdfs:label "dendritic cell" ;
rdfs:comment "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." ;
rdfs:subClassOf obo:CL_0000113 , obo:CL_0000145 , obo:CL_0000738 .
obo:CHEBI_88187 a rdfs:Class ;
rdfs:label "penicillin allergen" ;
rdfs:comment "Any penicillin which causes the onset of an allergic reaction." ;
rdfs:subClassOf obo:CHEBI_17334 .
obo:GO_0021756 a rdfs:Class ;
rdfs:label "striatum development" ;
rdfs:comment "The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0007798 a rdfs:Class ;
rdfs:label "vascular system" ;
rdfs:comment "Anatomical system that consists of all blood and lymph vessels." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:UBERON_0011249 a rdfs:Class ;
rdfs:label "appendicular skeletal system" ;
rdfs:comment "Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints." ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:CL_4042039 a rdfs:Class ;
rdfs:label "caudal ganglionic eminence derived neuron"@en ;
rdfs:comment "A neuron of the central nervous system that develops from a caudal ganglionic eminence." ;
rdfs:subClassOf obo:CL_2000029 .
obo:CHEBI_15379 a rdfs:Class .
obo:UBERON_0011858 a rdfs:Class ;
rdfs:label "acinus of exocrine gland" ;
rdfs:comment "An acinus that is part of a exocrine gland." ;
rdfs:subClassOf obo:UBERON_0009842 .
obo:UBERON_0000120 a rdfs:Class ;
rdfs:label "blood brain barrier" ;
rdfs:comment "Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions." ;
rdfs:subClassOf obo:UBERON_0000119 .
obo:CL_4307056 a rdfs:Class ;
rdfs:label "Astro-OLF NN_3 Sfrp1 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), 6530411M01Rik (Mmus), Sfrp1 (Mmus), Aqp4 (Mmus). It is distinguished from other Astro-OLF NN_3 cells by expression of Sfrp1, Aqp4. These cells are located in the Olfactory areas , in or close to the regions: Main olfactory bulb, granule layer, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5236 Astro-OLF NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301598 .
obo:GO_0003365 a rdfs:Class ;
rdfs:label "establishment of cell polarity involved in ameboidal cell migration" ;
rdfs:comment "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." ;
rdfs:subClassOf obo:GO_0030010 .
obo:CHEBI_51256 a rdfs:Class ;
rdfs:label "amoxicillin(1-)" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:CL_0008028 a rdfs:Class ;
rdfs:label "visual system neuron" ;
rdfs:comment "Any neuron that is capable of part of some visual perception." ;
rdfs:subClassOf obo:CL_0000540 .
obo:CL_4300348 a rdfs:Class ;
rdfs:label "DCO Il22 Gly-Gaba cerebellar neuron (Mmus)" ;
rdfs:comment "A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Tmem204 (Mmus), Slc6a5 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:308 DCO Il22 Gly-Gaba." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0008059 , obo:CL_4300028 .
obo:CHEBI_59770 a rdfs:Class ;
rdfs:label "cyclic acetal" ;
rdfs:comment "An acetal in the molecule of which the acetal carbon and one or both oxygen atoms thereon are members of a ring." ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_59769 .
obo:CHEBI_77906 a rdfs:Class ;
rdfs:label "minocycline zwitterion" ;
rdfs:comment "A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of minocycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." ;
rdfs:subClassOf obo:CHEBI_144644 , obo:CHEBI_27369 .
obo:GO_0051170 a rdfs:Class ;
rdfs:label "import into nucleus" ;
rdfs:comment "The directed movement of substances into the nucleus." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0006913 , obo:GO_0010496 .
obo:CHEBI_72588 a rdfs:Class ;
rdfs:label "semisynthetic derivative" ;
rdfs:comment "Any organic molecular entity derived from a natural product by partial chemical synthesis." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:GO_0035234 a rdfs:Class ;
rdfs:label "ectopic germ cell programmed cell death" ;
rdfs:comment "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0010623 , obo:GO_0012501 .
obo:CHEBI_26216 a rdfs:Class ;
rdfs:label "potassium atom" ;
rdfs:subClassOf obo:CHEBI_22314 , obo:CHEBI_50860 .
obo:GO_0002065 a rdfs:Class ;
rdfs:label "columnar/cuboidal epithelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030855 .
obo:GO_0009713 a rdfs:Class ;
rdfs:label "catechol-containing compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0009712 , obo:GO_0046189 .
obo:GO_0120223 a rdfs:Class ;
rdfs:label "larynx morphogenesis" ;
rdfs:comment "The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:CL_4300363 a rdfs:Class ;
rdfs:label "ependymal cell (Mmus)" ;
rdfs:comment "A ependymal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Tmem212 (Mmus), Rarres2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:323 Ependymal NN." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000065 .
obo:GO_0060282 a rdfs:Class ;
rdfs:label "positive regulation of oocyte development" ;
rdfs:comment "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0060281 , obo:GO_0065007 , obo:GO_2000243 .
obo:CHEBI_77255 a rdfs:Class ;
rdfs:label "EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor" ;
rdfs:comment "An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83)." ;
rdfs:subClassOf obo:CHEBI_59107 .
obo:GO_0010661 a rdfs:Class ;
rdfs:label "positive regulation of muscle cell apoptotic process" ;
rdfs:comment "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." ;
rdfs:subClassOf obo:GO_0010660 , obo:GO_0043065 , obo:GO_0065007 .
obo:UBERON_0034947 a rdfs:Class ;
rdfs:label "gas in respiratory system" ;
rdfs:comment "Any portion of gas located in a part of the respiratory system." ;
rdfs:subClassOf obo:UBERON_0034873 .
obo:UBERON_0004779 a rdfs:Class ;
rdfs:label "respiratory system lamina propria" ;
rdfs:comment "A lamina propria that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000030 .
obo:GO_0016325 a rdfs:Class ;
rdfs:label "oocyte microtubule cytoskeleton organization" ;
rdfs:comment "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0030951 .
obo:GO_0110058 a rdfs:Class ;
rdfs:label "positive regulation of blood vessel endothelial cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation." ;
rdfs:subClassOf obo:GO_0045603 , obo:GO_0065007 , obo:GO_0110057 .
obo:UBERON_0004859 a rdfs:Class ;
rdfs:label "eye gland" ;
rdfs:comment "A gland that is part of a eye. The eye is a compound unit which depending on the species may consist of an eyeballs plus associated ducts and integumentary structures. Eye glands therefore include the various types of lacrimal gland, the various types of apocrine and sebaceous glands associated with the eyelid." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:PR_000001869 a rdfs:Class ;
rdfs:label "interleukin-7 receptor subunit alpha" ;
rdfs:comment "A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_1902913 a rdfs:Class ;
rdfs:label "positive regulation of neuroepithelial cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation." ;
rdfs:subClassOf obo:GO_0030858 , obo:GO_0065007 .
obo:CHEBI_38702 a rdfs:Class ;
rdfs:label "inorganic sodium salt" ;
rdfs:subClassOf obo:CHEBI_24839 , obo:CHEBI_26714 .
obo:GO_1904412 a rdfs:Class ;
rdfs:label "regulation of cardiac ventricle development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac ventricle development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:PATO_0002083 a rdfs:Class ;
rdfs:label "altered number of" ;
rdfs:comment "Having extra or fewer parts." ;
rdfs:subClassOf obo:PATO_0000051 , obo:PATO_0001555 .
obo:GO_0070285 a rdfs:Class ;
rdfs:label "pigment cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:GO_0034219 a rdfs:Class ;
rdfs:label "carbohydrate transmembrane transport" ;
rdfs:comment "The process in which a carbohydrate is transported across a membrane." ;
rdfs:subClassOf obo:GO_0008643 , obo:GO_0055085 .
obo:CHEBI_24400 a rdfs:Class ;
rdfs:label "glycoside" ;
rdfs:comment "A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO‒, RS‒, RSe‒, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively." ;
rdfs:subClassOf obo:CHEBI_63161 .
obo:GO_0046928 a rdfs:Class ;
rdfs:label "regulation of neurotransmitter secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0051588 , obo:GO_0065007 , obo:GO_1903530 .
obo:UBERON_0001004 a rdfs:Class ;
rdfs:label "respiratory system" ;
rdfs:comment "Functional system which consists of structures involved in respiration." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:GO_0010637 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial fusion" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment." ;
rdfs:subClassOf obo:GO_0010635 , obo:GO_0010639 , obo:GO_0051093 , obo:GO_0065007 .
obo:GO_0048863 a rdfs:Class ;
rdfs:label "stem cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ;
rdfs:subClassOf obo:GO_0030154 .
obo:CHEBI_33833 a rdfs:Class ;
rdfs:label "heteroarene" ;
rdfs:comment "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33659 .
obo:GO_1904942 a rdfs:Class ;
rdfs:label "regulation of cardiac ventricle formation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac ventricle formation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901210 .
obo:PHIPO_0000871 a rdfs:Class ;
rdfs:label "sensitive to erythromycin A"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to erythromycin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000298 a rdfs:Class ;
rdfs:label "obsolete abnormal dissemination of pathogen asexual product" .
obo:CHEBI_24433 a rdfs:Class ;
rdfs:label "group" ;
rdfs:comment "A defined linked collection of atoms or a single atom within a molecular entity." ;
rdfs:subClassOf obo:CHEBI_24431 .
obo:GO_0002072 a rdfs:Class ;
rdfs:label "optic cup morphogenesis involved in camera-type eye development" ;
rdfs:comment "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0016331 .
obo:CHEBI_58464 a rdfs:Class ;
rdfs:label "nucleoside 3',5'-cyclic phosphate anion" ;
rdfs:comment "The conjugate base of a nucleoside 3',5'-cyclic phosphate." ;
rdfs:subClassOf obo:CHEBI_58945 .
obo:CHEBI_38329 a rdfs:Class ;
rdfs:label "oxazolidines" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 , obo:CHEBI_38104 .
obo:PHIPO_0000786 a rdfs:Class ;
rdfs:label "sensitive to oligomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to oligomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1902474 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to synapse" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to synapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902473 , obo:GO_1903829 .
obo:GO_0072175 a rdfs:Class ;
rdfs:label "epithelial tube formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of an epithelial tube." ;
rdfs:subClassOf obo:GO_0035148 .
obo:PHIPO_0000554 a rdfs:Class ;
rdfs:label "resistance to nisin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to nisin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_8480029 a rdfs:Class ;
rdfs:label "skin of external genitalia" ;
rdfs:comment "A zone of skin that is part of the external genitalia." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0005156 .
obo:GO_0098920 a rdfs:Class ;
rdfs:label "retrograde trans-synaptic signaling by lipid" ;
rdfs:comment "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand." ;
rdfs:subClassOf obo:GO_0098917 , obo:GO_0099537 , obo:GO_0099541 .
obo:GO_0002734 a rdfs:Class ;
rdfs:label "negative regulation of myeloid dendritic cell cytokine production" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production." ;
rdfs:subClassOf obo:GO_0002731 , obo:GO_0002733 , obo:GO_0002887 , obo:GO_0065007 .
obo:GO_0022414 a rdfs:Class ;
rdfs:label "reproductive process" ;
rdfs:comment "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." ;
rdfs:subClassOf obo:GO_0008150 .
obo:PR_000002981 a rdfs:Class ;
rdfs:label "lymphocyte antigen 76 (mouse)" ;
rdfs:comment "A protein that is a translation product of the Ly76 gene in mouse." ;
rdfs:subClassOf obo:PR_000029032 .
obo:UBERON_0000066 a rdfs:Class ;
rdfs:label "fully formed stage" ;
rdfs:comment "The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:GO_0060420 a rdfs:Class ;
rdfs:label "regulation of heart growth" ;
rdfs:comment "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." ;
rdfs:subClassOf obo:GO_0046620 , obo:GO_0065007 , obo:GO_2000026 .
obo:PHIPO_0000210 a rdfs:Class ;
rdfs:label "obsolete decreased extent and duration of pathogen host protein-protein interaction" ;
rdfs:comment "A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs to a lower extent, and for a shorter time, than normal." .
obo:UBERON_0002354 a rdfs:Class ;
rdfs:label "cardiac Purkinje fiber" ;
rdfs:comment "The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." ;
rdfs:subClassOf obo:UBERON_0010131 , obo:UBERON_0018649 .
obo:GO_0048755 a rdfs:Class ;
rdfs:label "branching morphogenesis of a nerve" ;
rdfs:comment "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)." ;
rdfs:subClassOf obo:GO_0001763 .
obo:GO_0060253 a rdfs:Class ;
rdfs:label "negative regulation of glial cell proliferation" ;
rdfs:comment "Any process that stops or decreases the rate or extent of glial cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0014014 , obo:GO_0060251 , obo:GO_0065007 .
obo:GO_1905128 a rdfs:Class ;
rdfs:label "positive regulation of axo-dendritic protein transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090316 , obo:GO_1905126 .
obo:UBERON_0000474 a rdfs:Class ;
rdfs:label "female reproductive system" ;
rdfs:comment "The organs and associated structures associated with bearing offspring in a female animal." ;
rdfs:subClassOf obo:UBERON_0000990 .
obo:CHEBI_29917 a rdfs:Class ;
rdfs:label "thiol group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:GO_0150099 a rdfs:Class ;
rdfs:label "neuron-glial cell signaling" ;
rdfs:comment "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine." ;
rdfs:subClassOf obo:GO_0007267 .
obo:UBERON_0005174 a rdfs:Class ;
rdfs:label "dorsal region element" ;
rdfs:comment "An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:CHEBI_83368 a rdfs:Class ;
rdfs:label "2,6-dimethyl-4-undecylmorpholine" ;
rdfs:comment "A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by an undecyl group. The configuration at positions 2 and 6 is unknown or unspecified." ;
rdfs:subClassOf obo:CHEBI_38785 , obo:CHEBI_50996 .
obo:CL_4030054 a rdfs:Class ;
rdfs:label "D1-NUDAP medium spiny neuron" ;
rdfs:comment "A DRD1-expressing medium spiny neuron that is part of dense, RXFP1-positive cell islands throughout the nucleus accumbens, putamen, and near the adjacent septal nuclei." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_1001474 .
obo:CHEBI_50276 a rdfs:Class ;
rdfs:label "EC 5.99.1.2 (DNA topoisomerase) inhibitor" ;
rdfs:comment "A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA." ;
rdfs:subClassOf obo:CHEBI_70727 .
obo:GO_0006611 a rdfs:Class ;
rdfs:label "protein export from nucleus" ;
rdfs:comment "The directed movement of a protein from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0006886 , obo:GO_0051168 .
obo:GO_0015171 a rdfs:Class ;
rdfs:label "amino acid transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group." ;
rdfs:subClassOf obo:GO_0022857 .
obo:GO_0032991 a rdfs:Class ;
rdfs:label "protein-containing complex" ;
rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ;
rdfs:subClassOf obo:COB_0000080 , obo:GO_0005575 .
obo:PHIPO_0001136 a rdfs:Class ;
rdfs:label "abolished development of asexual reproductive structure"@en ;
rdfs:comment "A single species phenotype where the asexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is abolished (it was present and is now absent) (GO:0048608)." ;
rdfs:subClassOf obo:PHIPO_0000121 .
obo:GO_0048565 a rdfs:Class ;
rdfs:label "digestive tract development" ;
rdfs:comment "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." ;
rdfs:subClassOf obo:GO_0035295 , obo:GO_0048856 .
obo:CL_4023064 a rdfs:Class ;
rdfs:label "caudal ganglionic eminence derived interneuron" ;
rdfs:comment "An interneuron that is derived from the caudal ganglionic eminence." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_0010011 , obo:CL_4042039 .
obo:GO_0035869 a rdfs:Class ;
rdfs:label "ciliary transition zone" ;
rdfs:comment "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CL_4307045 a rdfs:Class ;
rdfs:label "Astro-TE NN_3 Fam163a astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Fam163a (Mmus), Kcnq3 (Mmus), Kcnq1ot1 (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Fam163a, Nr2f1, Kcnq1ot1. These cells are located in the Isocortex, Olfactory areas . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5225 Astro-TE NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301593 .
obo:CL_4023079 a rdfs:Class ;
rdfs:label "midbrain-derived inhibitory neuron" ;
rdfs:comment "A GABAergic inhibitory neuron that is derived from the midbrain." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000029 , obo:UBERON_0004121 .
obo:CHEBI_46920 a rdfs:Class ;
rdfs:label "N-methylpiperazine" ;
rdfs:subClassOf obo:CHEBI_46845 .
obo:UBERON_0001650 a rdfs:Class ;
rdfs:label "hypoglossal nerve" ;
rdfs:comment "Cranial nerve that innervates the muscles of the tongue." ;
rdfs:subClassOf obo:UBERON_0001785 .
obo:CHEBI_34996 a rdfs:Class ;
rdfs:label "teicoplanin A2-3" ;
rdfs:comment "A teicoplanin A2 that has decanoyl as the variable N-acyl group." ;
rdfs:subClassOf obo:CHEBI_34994 .
obo:GO_0046886 a rdfs:Class ;
rdfs:label "positive regulation of hormone biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0032352 , obo:GO_0046885 , obo:GO_0065007 .
obo:GO_2000290 a rdfs:Class ;
rdfs:label "regulation of myotome development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of myotome development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0021536 a rdfs:Class ;
rdfs:label "diencephalon development" ;
rdfs:comment "The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0032885 a rdfs:Class ;
rdfs:label "regulation of polysaccharide biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides." ;
rdfs:subClassOf obo:GO_0010556 , obo:GO_0032881 , obo:GO_0043255 , obo:GO_0065007 .
obo:CHEBI_35701 a rdfs:Class ;
rdfs:label "ester" ;
rdfs:comment "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:GO_2000377 a rdfs:Class ;
rdfs:label "regulation of reactive oxygen species metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:CL_0017502 a rdfs:Class ;
rdfs:label "acidophilic cytoplasm" ;
rdfs:comment "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain." ;
rdfs:subClassOf obo:GO_0005737 .
obo:CL_0000440 a rdfs:Class ;
rdfs:label "melanocyte stimulating hormone secreting cell" ;
rdfs:comment "A cell of the intermediate pituitary that produces melanocyte stimulating hormone." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000167 .
obo:GO_0043935 a rdfs:Class ;
rdfs:label "sexual sporulation resulting in formation of a cellular spore" ;
rdfs:comment "The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction." ;
rdfs:subClassOf obo:GO_0030435 , obo:GO_0034293 .
obo:GO_0016525 a rdfs:Class ;
rdfs:label "negative regulation of angiogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis." ;
rdfs:subClassOf obo:GO_0045765 , obo:GO_0065007 , obo:GO_2000181 .
obo:CL_4023035 a rdfs:Class ;
rdfs:label "lateral ganglionic eminence derived neuron"@en ;
rdfs:comment "A neuron that is derived from a precursor cell in the lateral ganglion eminence." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_2000029 .
obo:GO_0030436 a rdfs:Class ;
rdfs:label "asexual sporulation" ;
rdfs:comment "The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0019954 , obo:GO_0043934 .
obo:UBERON_0002348 a rdfs:Class ;
rdfs:label "epicardium" ;
rdfs:comment "A region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart." ;
rdfs:subClassOf obo:UBERON_0000481 .
a rdfs:Class ;
rdfs:label "Pallidum, dorsal region" ;
rdfs:subClassOf , obo:UBERON_0006516 .
obo:PHIPO_0000588 a rdfs:Class ;
rdfs:label "resistance to trimethoprim"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to trimethoprim. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0003495 a rdfs:Class ;
rdfs:label "respiratory system arteriole" ;
rdfs:comment "An arteriole that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001980 , obo:UBERON_0003643 .
obo:CL_0002068 a rdfs:Class ;
rdfs:label "Purkinje myocyte" ;
rdfs:comment "Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter." ;
rdfs:subClassOf obo:CL_0002086 .
obo:CL_0008045 a rdfs:Class ;
rdfs:label "tanycyte of subcommissural organ" ;
rdfs:comment "A tanycyte of the subcommisural organ (SCO). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SCO, where they form a dense network surrounding these capillaries." ;
rdfs:subClassOf obo:CL_0002085 .
obo:GO_1902685 a rdfs:Class ;
rdfs:label "positive regulation of receptor localization to synapse" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of receptor localization to synapse." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0065007 , obo:GO_1902683 .
obo:UBERON_0015410 a rdfs:Class ;
rdfs:label "heart plus pericardium" ;
rdfs:subClassOf obo:UBERON_0005178 .
obo:CHEBI_30746 a rdfs:Class ;
rdfs:label "benzoic acid" ;
rdfs:comment "A compound comprising a benzene ring core carrying a carboxylic acid substituent." ;
rdfs:subClassOf obo:CHEBI_22723 .
obo:CHEBI_87067 a rdfs:Class ;
rdfs:label "conazole fungicide" ;
rdfs:comment "Any conazole antifungal agent that has been used as a fungicide." ;
rdfs:subClassOf obo:CHEBI_86323 .
obo:GO_0120036 a rdfs:Class ;
rdfs:label "plasma membrane bounded cell projection organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0030030 .
obo:PHIPO_0000100 a rdfs:Class ;
rdfs:label "obsolete increased motility" .
obo:GO_0042435 a rdfs:Class ;
rdfs:label "indole-containing compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0042430 .
obo:CHEBI_37943 a rdfs:Class ;
rdfs:label "colistin" ;
rdfs:comment "A multi-component mixture comprising mostly of colistin A (R = Me) and B (R = H), with small amounts of colistin C and other polymyxins, produced by certain strains of Bacillus polymyxa var. colistinus. An antibiotic, it is used as its sulfate salt (for oral or topical use) or as the sodium salt of the N-methylsulfonic acid derivative (the injectable form) in the treatment of severe Gram-negative infections, partiularly those due to Pseudomonas aeruginosa." ;
rdfs:subClassOf obo:CHEBI_25903 , obo:CHEBI_59062 .
obo:GO_1903338 a rdfs:Class ;
rdfs:label "regulation of cell wall organization or biogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0042429 a rdfs:Class ;
rdfs:label "serotonin catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0019336 , obo:GO_0042428 , obo:GO_0042436 , obo:GO_1901161 .
obo:CHEBI_38390 a rdfs:Class ;
rdfs:label "9,11,15-octadecatrienoate" ;
rdfs:comment "Any octadecatrienoate having double bonds at positions 9, 11 and 15." ;
rdfs:subClassOf obo:CHEBI_36434 .
obo:UBERON_0010959 a rdfs:Class ;
rdfs:label "craniocervical muscle" ;
rdfs:comment "Any muscle organ that is part of either the head or the neck." ;
rdfs:subClassOf obo:UBERON_0014892 .
obo:UBERON_0002185 a rdfs:Class ;
rdfs:label "bronchus" ;
rdfs:comment "The upper conducting airways of the lung; these airways arise from the terminus of the trachea." ;
rdfs:subClassOf obo:UBERON_0000117 .
obo:CL_0002262 a rdfs:Class ;
rdfs:label "endothelial cell of sinusoid" ;
rdfs:comment "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver." ;
rdfs:subClassOf obo:CL_0000071 , obo:CL_0000115 .
obo:GO_0048340 a rdfs:Class ;
rdfs:label "paraxial mesoderm morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the paraxial mesoderm are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048332 , obo:GO_0072132 .
obo:UBERON_0007240 a rdfs:Class ;
rdfs:label "tunica adventitia of artery" ;
rdfs:comment "A tunica adventitia that is part of a artery." ;
rdfs:subClassOf obo:UBERON_0005734 .
obo:PHIPO_0000465 a rdfs:Class ;
rdfs:label "absence of pathogen necrotrophic effector-mediated host programmed cell death"@en ;
rdfs:comment "A phenotype where the process of a necrotrophic pathogen effector activating the host immune system to trigger programmed cell death is absent." ;
rdfs:subClassOf obo:PHIPO_0000280 , obo:PHIPO_0000481 .
obo:CL_4307110 a rdfs:Class ;
rdfs:label "OEC NN_1 Gdpd4 olfactory ensheathing cell (Mmus)" ;
rdfs:comment "A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Aqp1 (Mmus), Cldn5 (Mmus). It is distinguished from other OEC cells by expression of Gdpd4, Cldn5. These cells are located in the brain , in or close to the regions: olfactory nerve layer of main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5290 OEC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301615 .
obo:GO_0045657 a rdfs:Class ;
rdfs:label "positive regulation of monocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of monocyte differentiation." ;
rdfs:subClassOf obo:GO_0002763 , obo:GO_0045655 , obo:GO_0065007 .
obo:GO_0016597 a rdfs:Class ;
rdfs:label "amino acid binding" ;
rdfs:comment "Binding to an amino acid, organic acids containing one or more amino substituents." ;
rdfs:subClassOf obo:GO_0005488 .
obo:CHEBI_35313 a rdfs:Class ;
rdfs:label "hexoside" ;
rdfs:subClassOf obo:CHEBI_24400 .
obo:GO_0007398 a rdfs:Class ;
rdfs:label "ectoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." ;
rdfs:subClassOf obo:GO_0009888 , obo:GO_0048856 .
obo:CL_0000333 a rdfs:Class ;
rdfs:label "migratory neural crest cell" ;
rdfs:comment "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body." ;
rdfs:subClassOf obo:CL_0000219 , obo:CL_0000255 , obo:CL_0011012 , obo:CL_0011026 .
obo:GO_1904216 a rdfs:Class ;
rdfs:label "positive regulation of protein import into chloroplast stroma" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma." ;
rdfs:subClassOf obo:GO_0034764 , obo:GO_0051222 , obo:GO_0065007 , obo:GO_1904215 .
obo:GO_0009968 a rdfs:Class ;
rdfs:label "negative regulation of signal transduction" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0010648 , obo:GO_0023057 , obo:GO_0048585 , obo:GO_0065007 .
obo:UBERON_0010133 a rdfs:Class ;
rdfs:label "neuroendocrine gland" ;
rdfs:comment "Any of the organized aggregations of cells that function as secretory or excretory organs and that release hormones in response to neural stimuli." ;
rdfs:subClassOf obo:UBERON_0002368 .
obo:GO_0051622 a rdfs:Class ;
rdfs:label "negative regulation of norepinephrine uptake" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell." ;
rdfs:subClassOf obo:GO_0051051 , obo:GO_0051621 , obo:GO_0065007 .
obo:CL_4307096 a rdfs:Class ;
rdfs:label "COP NN_1 Vwc2 committed oligodendrocyte precursor (Mmus)" ;
rdfs:comment "A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Rab32 (Mmus), Opalin (Mmus). It is distinguished from other COP NN_1 cells by expression of Vwc2, Opalin. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5276 COP NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301611 .
obo:GO_0055017 a rdfs:Class ;
rdfs:label "cardiac muscle tissue growth" ;
rdfs:comment "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." ;
rdfs:subClassOf obo:GO_0048589 .
obo:PHIPO_0000405 a rdfs:Class ;
rdfs:label "normal unicellular population growth"@en ;
rdfs:comment "A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000162 .
obo:UBERON_0007367 a rdfs:Class ;
rdfs:label "surface of tongue" ;
rdfs:comment "An anatomical surface that is part of a tongue." ;
rdfs:subClassOf obo:UBERON_0036215 .
obo:GO_0032042 a rdfs:Class ;
rdfs:label "mitochondrial DNA metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving mitochondrial DNA." ;
rdfs:subClassOf obo:GO_0006259 .
obo:GO_0035556 a rdfs:Class ;
rdfs:label "intracellular signal transduction" ;
rdfs:comment "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." ;
rdfs:subClassOf obo:GO_0007165 .
obo:CHEBI_53670 a rdfs:Class ;
rdfs:label "cefotaxime(1-)" ;
rdfs:comment "A cephalosporin carboxylic acid anion having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups, formed by proton loss from the carboxy group of the cephalosporin cefotaxime." ;
rdfs:subClassOf obo:CHEBI_52440 .
obo:UBERON_0010077 a rdfs:Class ;
rdfs:label "cuboidal epithelium" ;
rdfs:comment "An epithelium consisting of cuboidal epithelial cells." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:PHIPO_0001395 a rdfs:Class ;
rdfs:label "sensitive to trifloxystrobin" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to trifloxystrobin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0045597 a rdfs:Class ;
rdfs:label "positive regulation of cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0048522 , obo:GO_0051094 , obo:GO_0065007 .
obo:CHEBI_17822 a rdfs:Class ;
rdfs:label "serine" ;
rdfs:comment "An α-amino acid that is alanine substituted at position 3 by a hydroxy group." ;
rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 .
obo:GO_0048643 a rdfs:Class ;
rdfs:label "positive regulation of skeletal muscle tissue development" ;
rdfs:comment "Any process that activates, maintains or increases the rate of skeletal muscle tissue development." ;
rdfs:subClassOf obo:GO_0045844 , obo:GO_0048641 , obo:GO_0065007 .
obo:GO_0002698 a rdfs:Class ;
rdfs:label "negative regulation of immune effector process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process." ;
rdfs:subClassOf obo:GO_0002683 , obo:GO_0002697 , obo:GO_0065007 .
obo:CHEBI_75835 a rdfs:Class ;
rdfs:label "anti-anaemic agent" ;
rdfs:comment "A compound which increases either the number of red cells or the amount of haemoglobin in the blood." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_0097447 a rdfs:Class ;
rdfs:label "dendritic tree" ;
rdfs:comment "The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches." ;
rdfs:subClassOf obo:GO_0043005 .
obo:GO_0050920 a rdfs:Class ;
rdfs:label "regulation of chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ;
rdfs:subClassOf obo:GO_0032101 , obo:GO_0040012 , obo:GO_0065007 .
obo:UBERON_0003929 a rdfs:Class ;
rdfs:label "digestive tract epithelium" ;
rdfs:comment "An epithelium that lines the lumen of the digestive tract." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0031452 a rdfs:Class ;
rdfs:label "negative regulation of heterochromatin formation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation." ;
rdfs:subClassOf obo:GO_0010628 , obo:GO_0031445 , obo:GO_0065007 , obo:GO_0120262 .
obo:GO_0044060 a rdfs:Class ;
rdfs:label "regulation of endocrine process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." ;
rdfs:subClassOf obo:GO_0044057 , obo:GO_0065007 .
obo:GO_1901221 a rdfs:Class ;
rdfs:label "positive regulation of cardiac chamber morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_1901219 .
obo:GO_1904587 a rdfs:Class ;
rdfs:label "response to glycoprotein" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_1901700 .
obo:GO_0003403 a rdfs:Class ;
rdfs:label "optic vesicle formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PHIPO_0001132 a rdfs:Class ;
rdfs:label "increased size of pathogen vacuoles during host colonization"@en ;
rdfs:comment "A pathogen host interaction phenotype where the size of the pathogen vacuoles are larger than normal during host colonization. This relates to the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0000999 .
obo:GO_0097529 a rdfs:Class ;
rdfs:label "myeloid leukocyte migration" ;
rdfs:comment "The movement of a myeloid leukocyte within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0050900 .
obo:PHIPO_0001085 a rdfs:Class ;
rdfs:label "decreased unicellular population growth rate"@en ;
rdfs:comment "A single species population growth phenotype where the rate of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is slower than normal." ;
rdfs:subClassOf obo:PHIPO_0000974 .
obo:CHEBI_17334 a rdfs:Class ;
rdfs:label "penicillin" ;
rdfs:comment "Any member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6." ;
rdfs:subClassOf obo:CHEBI_25865 .
obo:PHIPO_0000810 a rdfs:Class ;
rdfs:label "sensitive to flutriafol"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to flutriafol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_8410081 a rdfs:Class ;
rdfs:label "blood microvessel" ;
rdfs:comment "Any of the smallest blood vessels where blood circulates within organ tissues. Microvessels include terminal arterioles, metarterioles, capillaries, and venules (but exclude lymphatic capillaries). Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0010523 .
obo:GO_0048582 a rdfs:Class ;
rdfs:label "positive regulation of post-embryonic development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ;
rdfs:subClassOf obo:GO_0048580 , obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 .
obo:CL_0000078 a rdfs:Class ;
rdfs:label "peridermal cell" ;
rdfs:comment "Any squamous epithelial cell that is part of some periderm." ;
rdfs:subClassOf obo:CL_0000076 , obo:CL_0000362 .
obo:UBERON_0010707 a rdfs:Class ;
rdfs:label "appendage girdle complex" ;
rdfs:comment "An organism subdivision that includes both an appendage and its associated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc)." ;
rdfs:subClassOf obo:UBERON_0000475 , obo:UBERON_0015212 .
obo:CL_4072002 a rdfs:Class ;
rdfs:label "myelin-forming oligodendrocyte"@en ;
rdfs:comment "A postmitotic and differentiated oligodendrocyte derived from a oligodendrocyte progenitor cell. A myelin-forming oligodendrocyte begins the expression of myelin genes and actively engages in the myelination process. In mice and humans, it is characterized by the upregulation of the key myelin-associated markers Mbp and Opalin. Additionally, Ctps (CTP synthase) shows peak expression at this stage, suggesting a heightened demand for nucleotide biosynthesis during membrane expansion and myelin production." ;
rdfs:subClassOf obo:CL_0000128 , obo:UBERON_0004121 .
obo:GO_0098967 a rdfs:Class ;
rdfs:label "exocytic insertion of neurotransmitter receptor to postsynaptic membrane" ;
rdfs:comment "The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion." ;
rdfs:subClassOf obo:GO_0006887 , obo:GO_0099072 .
obo:CHEBI_38311 a rdfs:Class ;
rdfs:label "cephem" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_27933 , obo:CHEBI_38106 .
obo:UBERON_0002343 a rdfs:Class ;
rdfs:label "abdomen musculature" ;
rdfs:comment "Set of all muscles in abdomen." ;
rdfs:subClassOf obo:UBERON_0001015 , obo:UBERON_0004479 .
obo:GO_0110059 a rdfs:Class ;
rdfs:label "negative regulation of blood vessel endothelial cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation." ;
rdfs:subClassOf obo:GO_0045602 , obo:GO_0065007 , obo:GO_0110057 .
obo:UBERON_0006966 a rdfs:Class ;
rdfs:label "coronary capillary" ;
rdfs:comment "A capillary that is part of the coronary system." ;
rdfs:subClassOf obo:UBERON_0001982 , obo:UBERON_0003498 .
obo:GO_0042181 a rdfs:Class ;
rdfs:label "ketone biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." ;
rdfs:subClassOf obo:GO_0042180 , obo:GO_0044283 .
obo:GO_0043535 a rdfs:Class ;
rdfs:label "regulation of blood vessel endothelial cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels." ;
rdfs:subClassOf obo:GO_0010594 , obo:GO_0065007 .
obo:GO_0003207 a rdfs:Class ;
rdfs:label "cardiac chamber formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PHIPO_0001055 a rdfs:Class ;
rdfs:label "obsolete increased size of colony" ;
rdfs:comment "A single species colony morphology phenotype where the size of the population is increased." .
obo:CL_0002074 a rdfs:Class ;
rdfs:label "myocardial endocrine cell" ;
rdfs:comment "The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides)." ;
rdfs:subClassOf obo:CL_0000163 , obo:CL_0002086 .
obo:CHEBI_29277 a rdfs:Class ;
rdfs:label "dinitride(2-)" ;
rdfs:subClassOf obo:CHEBI_33266 .
obo:GO_0043227 a rdfs:Class ;
rdfs:label "membrane-bounded organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0043226 .
obo:GO_0061053 a rdfs:Class ;
rdfs:label "somite development" ;
rdfs:comment "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060429 .
obo:GO_1901693 a rdfs:Class ;
rdfs:label "negative regulation of compound eye retinal cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0065007 , obo:GO_1901692 .
obo:GO_0014033 a rdfs:Class ;
rdfs:label "neural crest cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0048762 , obo:GO_0048863 .
obo:GO_0021859 a rdfs:Class ;
rdfs:label "pyramidal neuron differentiation" ;
rdfs:comment "The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron." ;
rdfs:subClassOf obo:GO_0021953 , obo:GO_0030154 .
obo:GO_0072360 a rdfs:Class ;
rdfs:label "vascular cord development" ;
rdfs:comment "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0010821 a rdfs:Class ;
rdfs:label "regulation of mitochondrion organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:GO_0005614 a rdfs:Class ;
rdfs:label "interstitial matrix" ;
rdfs:comment "A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens." ;
rdfs:subClassOf obo:GO_0031012 .
obo:UBERON_0002419 a rdfs:Class ;
rdfs:label "skin gland" ;
rdfs:comment "A gland that is part of a skin of body [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002530 , obo:UBERON_0003297 , obo:UBERON_0006003 .
obo:GO_0009063 a rdfs:Class ;
rdfs:label "amino acid catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." ;
rdfs:subClassOf obo:GO_0006520 , obo:GO_0009056 .
obo:PHIPO_0000524 a rdfs:Class ;
rdfs:label "resistance to ketoconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ketoconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0061082 a rdfs:Class ;
rdfs:label "myeloid leukocyte cytokine production" ;
rdfs:comment "Any process that contributes to cytokine production by a myeloid cell." ;
rdfs:subClassOf obo:GO_0002367 .
obo:GO_0051659 a rdfs:Class ;
rdfs:label "maintenance of mitochondrion location" ;
rdfs:comment "Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0051646 , obo:GO_0051651 , obo:GO_0051657 .
obo:GO_0003379 a rdfs:Class ;
rdfs:label "establishment of cell polarity involved in gastrulation cell migration" ;
rdfs:comment "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." ;
rdfs:subClassOf obo:GO_0003365 , obo:GO_0030010 .
obo:CHEBI_38499 a rdfs:Class ;
rdfs:label "mitochondrial cytochrome-bc1 complex inhibitor" ;
rdfs:subClassOf obo:CHEBI_25355 , obo:CHEBI_38502 .
obo:CHEBI_35469 a rdfs:Class ;
rdfs:label "antidepressant" ;
rdfs:comment "Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions." ;
rdfs:subClassOf obo:CHEBI_35471 .
obo:GO_0061025 a rdfs:Class ;
rdfs:label "membrane fusion" ;
rdfs:comment "The membrane organization process that joins two lipid bilayers to form a single membrane." ;
rdfs:subClassOf obo:GO_0061024 .
obo:GO_0010713 a rdfs:Class ;
rdfs:label "negative regulation of collagen metabolic process" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0010712 , obo:GO_0065007 .
obo:UBERON_0004807 a rdfs:Class ;
rdfs:label "respiratory system epithelium" ;
rdfs:comment "An epithelium that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0050867 a rdfs:Class ;
rdfs:label "positive regulation of cell activation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of activation." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0050865 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0003281 a rdfs:Class ;
rdfs:label "ventricular septum development" ;
rdfs:comment "The progression of the ventricular septum over time from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0003279 , obo:GO_0048856 .
obo:PHIPO_0000072 a rdfs:Class ;
rdfs:label "abnormal sexual spore shape"@en ;
rdfs:comment "A reproductive morphology phenotype where the shape of the sexual spore is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000130 .
obo:UBERON_0004742 a rdfs:Class ;
rdfs:label "dentary" ;
rdfs:comment "The dentary is a dermal bone that forms the antero-lateral part of the lower jaw in fishes and amphibians, extending to the whole lower jaw in mammals[VHOG,modified]." ;
rdfs:subClassOf obo:UBERON_0004768 , obo:UBERON_0008907 , obo:UBERON_0015212 .
obo:GO_0031269 a rdfs:Class ;
rdfs:label "pseudopodium assembly" ;
rdfs:comment "The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0031268 , obo:GO_0120031 .
obo:UBERON_0002323 a rdfs:Class ;
rdfs:label "coelemic cavity lumen" ;
rdfs:comment "The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities." ;
rdfs:subClassOf obo:UBERON_0002553 .
obo:GO_0050657 a rdfs:Class ;
rdfs:label "nucleic acid transport" ;
rdfs:comment "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015931 .
obo:GO_0089718 a rdfs:Class ;
rdfs:label "amino acid import across plasma membrane" ;
rdfs:comment "The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol." ;
rdfs:subClassOf obo:GO_0003333 , obo:GO_0006810 , obo:GO_0098739 .
obo:CL_0000197 a rdfs:Class ;
rdfs:label "sensory receptor cell" ;
rdfs:comment "A cell that is capable of detection of a stimulus involved in sensory perception." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:CHEBI_26509 a rdfs:Class ;
rdfs:label "quinoline alkaloid" ;
rdfs:subClassOf obo:CHEBI_22315 .
obo:CHEBI_33233 a rdfs:Class ;
rdfs:label "fundamental particle" ;
rdfs:comment "A particle not known to have substructure." ;
rdfs:subClassOf obo:CHEBI_36342 .
obo:GO_0048593 a rdfs:Class ;
rdfs:label "camera-type eye morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048592 .
obo:GO_0002285 a rdfs:Class ;
rdfs:label "lymphocyte activation involved in immune response" ;
rdfs:comment "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0002366 , obo:GO_0046649 .
obo:GO_0007215 a rdfs:Class ;
rdfs:label "glutamate receptor signaling pathway" ;
rdfs:comment "The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription." ;
rdfs:subClassOf obo:GO_0007165 , obo:GO_0007166 .
obo:GO_0048806 a rdfs:Class ;
rdfs:label "genitalia development" ;
rdfs:comment "The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048608 .
obo:CHEBI_33515 a rdfs:Class ;
rdfs:label "transition element cation" ;
rdfs:subClassOf obo:CHEBI_25213 .
obo:CL_0000052 a rdfs:Class ;
rdfs:label "totipotent stem cell" ;
rdfs:comment "A stem cell from which all cells of the body can form." ;
rdfs:subClassOf obo:CL_0000723 .
obo:CHEBI_66956 a rdfs:Class ;
rdfs:label "antidyskinesia agent" ;
rdfs:comment "Any compound which can be used to treat or alleviate the symptoms of dyskinesia." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:UBERON_0016887 a rdfs:Class ;
rdfs:label "entire extraembryonic component" ;
rdfs:comment "The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism." ;
rdfs:subClassOf obo:UBERON_0000481 .
obo:UBERON_0000970 a rdfs:Class ;
rdfs:label "eye" ;
rdfs:comment "An organ that detects light." ;
rdfs:subClassOf obo:UBERON_0000020 .
obo:CHEBI_26712 a rdfs:Class ;
rdfs:label "sodium molecular entity" ;
rdfs:subClassOf obo:CHEBI_33296 .
obo:PHIPO_0000195 a rdfs:Class ;
rdfs:label "obsolete normal host lesion formation with pathogen" .
obo:GO_1902250 a rdfs:Class ;
rdfs:label "regulation of erythrocyte apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process." ;
rdfs:subClassOf obo:GO_0033032 , obo:GO_0065007 .
obo:CL_4307085 a rdfs:Class ;
rdfs:label "CHOR NN_1 Slc17a8 choroid plexus epithelial cell (Mmus)" ;
rdfs:comment "A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus), Slc17a8 (Mmus). It is distinguished from other CHOR NN cells by expression of Slc17a8. It is glutamatergic (inferred from expression of Slc17a8). These cells are located in the brain , in or close to the regions: choroid plexus, lateral ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5265 CHOR NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000686 , obo:CL_4301608 .
obo:CHEBI_16541 a rdfs:Class ;
rdfs:label "protein polypeptide chain" ;
rdfs:comment "A naturally occurring polypeptide synthesized at the ribosome." ;
rdfs:subClassOf obo:CHEBI_15841 .
obo:GO_0030214 a rdfs:Class ;
rdfs:label "hyaluronan catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine." ;
rdfs:subClassOf obo:GO_0006027 , obo:GO_0009056 , obo:GO_0030212 .
obo:GO_0010638 a rdfs:Class ;
rdfs:label "positive regulation of organelle organization" ;
rdfs:comment "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0051130 , obo:GO_0065007 .
obo:CHEBI_33663 a rdfs:Class ;
rdfs:label "cyclic hydrocarbon" ;
rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_33598 .
obo:CHEBI_83749 a rdfs:Class ;
rdfs:label "(2R,3S)-cyproconazole" ;
rdfs:comment "The (2R,3S)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol." ;
rdfs:subClassOf obo:CHEBI_83748 .
obo:GO_0002372 a rdfs:Class ;
rdfs:label "myeloid dendritic cell cytokine production" ;
rdfs:comment "Any process that contributes to cytokine production by a myeloid dendritic cell." ;
rdfs:subClassOf obo:GO_0001816 , obo:GO_0002371 , obo:GO_0002444 , obo:GO_0061082 .
obo:CHEBI_33597 a rdfs:Class ;
rdfs:label "homocyclic compound" ;
rdfs:comment "A cyclic compound having as ring members atoms of the same element only." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:CHEBI_72600 a rdfs:Class ;
rdfs:label "spiroketal" ;
rdfs:comment "A cyclic ketal in which the ketal carbon is the only common atom of two rings." ;
rdfs:subClassOf obo:CHEBI_37948 , obo:CHEBI_59779 .
obo:PHIPO_0001020 a rdfs:Class ;
rdfs:label "sensitive to calcofluor white"@en ;
rdfs:comment "A phenotype in which a population of a single-species shows increased sensitivity to calcofluor white, manifested as an affect on the extent of population growth. (CHEBI:50011)" ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CL_0002363 a rdfs:Class ;
rdfs:label "keratocyte" ;
rdfs:comment "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate." ;
rdfs:subClassOf obo:CL_0000005 , obo:CL_0000057 .
obo:CL_4307048 a rdfs:Class ;
rdfs:label "Astro-TE NN_4 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Thbs4 (Mmus), Gm29683 (Mmus), Slc39a12 (Mmus). It is distinguished from other Astro-TE NN cells by expression of Gm29683. These cells are located in the Cortical subplate, brain , in or close to the regions: Lateral amygdalar nucleus, external capsule . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5228 Astro-TE NN_4." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300359 .
obo:UBERON_0002204 a rdfs:Class ;
rdfs:label "musculoskeletal system" ;
rdfs:comment "Anatomical system that consists of the muscular and skeletal systems." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:CHEBI_77745 a rdfs:Class ;
rdfs:label "EC 3.4.24.18 (meprin A) inhibitor" ;
rdfs:comment "An EC 3.4.24.* (metalloendopeptidase) inhibitor that inhibits the action of meprin A (EC 3.4.24.18)." ;
rdfs:subClassOf obo:CHEBI_59107 .
obo:GO_0032058 a rdfs:Class ;
rdfs:label "positive regulation of translational initiation in response to stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0045948 , obo:GO_0065007 .
obo:GO_0030851 a rdfs:Class ;
rdfs:label "granulocyte differentiation" ;
rdfs:comment "The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils." ;
rdfs:subClassOf obo:GO_0002573 , obo:GO_0030154 .
obo:CL_0002308 a rdfs:Class ;
rdfs:label "epithelial cell of skin gland" ;
rdfs:comment "An epithelial cell of a skin gland." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002159 .
obo:CHEBI_49167 a rdfs:Class ;
rdfs:label "anti-asthmatic drug" ;
rdfs:comment "A drug used to treat asthma." ;
rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_65023 .
obo:CHEBI_35222 a rdfs:Class ;
rdfs:label "inhibitor" ;
rdfs:comment "A substance that diminishes the rate of a chemical reaction." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_33504 a rdfs:Class ;
rdfs:label "alkali metal cation" ;
rdfs:subClassOf obo:CHEBI_25213 .
obo:UBERON_0022303 a rdfs:Class ;
rdfs:label "nervous system cell part layer" ;
rdfs:comment "Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]." ;
rdfs:subClassOf obo:UBERON_0005162 .
obo:PHIPO_0000658 a rdfs:Class ;
rdfs:label "resistance to amoxicillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to amoxicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:GO_0021773 a rdfs:Class ;
rdfs:label "striatal medium spiny neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum." ;
rdfs:subClassOf obo:GO_0021879 , obo:GO_0030154 , obo:GO_0097154 .
obo:UBERON_0006606 a rdfs:Class ;
rdfs:label "mandibular symphysis" ;
rdfs:comment "A cartilaginous joint that connects left and right mandibles/dentary bones. Mandibular symphysis is unpaired[TAO,modified]." ;
rdfs:subClassOf obo:UBERON_0002213 , obo:UBERON_0002216 .
obo:CL_2000066 a rdfs:Class ;
rdfs:label "cardiac ventricle fibroblast" ;
rdfs:comment "Any fibroblast that is part of a cardiac ventricle." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0002548 .
obo:UBERON_0004911 a rdfs:Class ;
rdfs:label "epithelium of female gonad" ;
rdfs:comment "An epithelium surrounding an ovary." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004909 .
obo:CL_0008008 a rdfs:Class ;
rdfs:label "striated visceral muscle cell"@en ;
rdfs:comment "A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods." ;
rdfs:subClassOf obo:CL_0000737 , obo:CL_0008007 .
obo:GO_0008219 a rdfs:Class ;
rdfs:label "cell death" ;
rdfs:comment "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." ;
rdfs:subClassOf obo:GO_0009987 .
obo:PHIPO_0000250 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction RNA localization phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the localization of an RNA in a cell." .
obo:GO_0060326 a rdfs:Class ;
rdfs:label "cell chemotaxis" ;
rdfs:comment "The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0016477 .
obo:GO_0140239 a rdfs:Class ;
rdfs:label "postsynaptic endocytosis" ;
rdfs:comment "A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." ;
rdfs:subClassOf obo:GO_0006897 , obo:GO_0051649 , obo:GO_0099003 .
obo:GO_0012505 a rdfs:Class ;
rdfs:label "endomembrane system" ;
rdfs:comment "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0009058 a rdfs:Class ;
rdfs:label "biosynthetic process" ;
rdfs:comment "A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." ;
rdfs:subClassOf obo:GO_0008152 .
obo:PHIPO_0001035 a rdfs:Class ;
rdfs:label "decreased level of substance in cell"@en ;
rdfs:comment "A single species cell phenotype in which the amount of a specific substance measured in a cell is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0000944 .
obo:GO_0099143 a rdfs:Class ;
rdfs:label "presynaptic actin cytoskeleton" ;
rdfs:comment "The actin cytoskeleton that is part of a presynapse." ;
rdfs:subClassOf obo:GO_0015629 , obo:GO_0099569 .
obo:NCBITaxon_89593 a rdfs:Class ;
rdfs:label "Craniata " ;
rdfs:subClassOf obo:NCBITaxon_7711 .
obo:PHIPO_0000861 a rdfs:Class ;
rdfs:label "sensitive to cycloheximide"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cycloheximide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PATO_0002050 a rdfs:Class ;
rdfs:label "normal amount" ;
rdfs:comment "An amount which normal." ;
rdfs:subClassOf obo:PATO_0000467 .
obo:GO_0003235 a rdfs:Class ;
rdfs:label "sinus venosus development" ;
rdfs:comment "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." ;
rdfs:subClassOf obo:GO_0003205 , obo:GO_0048856 .
obo:CHEBI_35871 a rdfs:Class ;
rdfs:label "oxo monocarboxylic acid" ;
rdfs:comment "Any monocarboxylic acid having at least one additional oxo functional group." ;
rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_25754 .
a rdfs:Class ;
rdfs:label "Cortical plate" ;
rdfs:subClassOf , obo:UBERON_0005343 .
obo:CHEBI_72447 a rdfs:Class ;
rdfs:label "2-deoxystreptamine(1+)" ;
rdfs:comment "An organic cation obtained by protonation of one of the two free amino groups of 2-deoxystreptamine." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:CHEBI_37022 a rdfs:Class ;
rdfs:label "amino-acid anion" ;
rdfs:subClassOf obo:CHEBI_29067 , obo:CHEBI_35352 .
obo:PHIPO_0000940 a rdfs:Class ;
rdfs:label "abnormal germ tube"@en ;
rdfs:comment "A single species phenotype where the slender tubular outgrowth first produced by most spores in germination is abnormal. (GO:0032179)" ;
rdfs:subClassOf obo:PHIPO_0000415 .
obo:PR_000032148 a rdfs:Class ;
rdfs:label "lysosome-associated membrane glycoprotein 5" ;
rdfs:comment "A protein that is a translation product of the human LAMP5 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0003279 a rdfs:Class ;
rdfs:label "endothelium of trachea" ;
rdfs:comment "An endothelium that is part of a trachea." ;
rdfs:subClassOf obo:UBERON_0000077 , obo:UBERON_0001901 , obo:UBERON_0001986 .
obo:CHEBI_46662 a rdfs:Class ;
rdfs:label "mineral" ;
rdfs:comment "In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals')." ;
rdfs:subClassOf obo:CHEBI_59999 .
obo:CL_4310123 a rdfs:Class ;
rdfs:label "STR SST-CHODL GABA sst chodl GABAergic interneuron (Primate)" ;
rdfs:comment "A sst chodl GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-CHODL GABA." ;
rdfs:subClassOf obo:CL_4023121 .
a rdfs:Class ;
rdfs:label "Nucleus accumbens" ;
rdfs:subClassOf , obo:UBERON_0001882 .
obo:GO_2000146 a rdfs:Class ;
rdfs:label "negative regulation of cell motility" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." ;
rdfs:subClassOf obo:GO_0040013 , obo:GO_0048523 , obo:GO_0065007 , obo:GO_2000145 .
obo:GO_0045137 a rdfs:Class ;
rdfs:label "development of primary sexual characteristics" ;
rdfs:comment "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." ;
rdfs:subClassOf obo:GO_0003006 .
obo:PHIPO_0000553 a rdfs:Class ;
rdfs:label "resistance to aztreonam"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to aztreonam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1905954 a rdfs:Class ;
rdfs:label "positive regulation of lipid localization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lipid localization." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0065007 , obo:GO_1905952 .
obo:CHEBI_3505 a rdfs:Class ;
rdfs:label "cefpodoxime proxetil" ;
rdfs:comment "The 1-[(isopropoxycarbonyl)oxy]ethyl (proxetil) ester prodrug of cefpodoxime. After swallowing, hydrolysis of the ester group occurs in the intestinal epithelium, to release active cefpodoxime in the bloodstream. It is used to treat acute otitis media, pharyngitis, and sinusitis." ;
rdfs:subClassOf obo:CHEBI_23066 , obo:CHEBI_33308 , obo:CHEBI_33575 , obo:CHEBI_60911 .
obo:PHIPO_0000814 a rdfs:Class ;
rdfs:label "sensitive to closantel"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to closantel. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0001083 a rdfs:Class ;
rdfs:label "myocardium of ventricle" ;
rdfs:comment "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer." ;
rdfs:subClassOf obo:UBERON_0002349 .
obo:PHIPO_0001147 a rdfs:Class ;
rdfs:label "cellular metabolic process phenotype"@en ;
rdfs:comment "A single organism phenotype that affects the chemical reactions and pathways by which individual cells transform chemical substances. (GO:0044237)" ;
rdfs:subClassOf obo:PHIPO_0000492 .
obo:UBERON_0034711 a rdfs:Class ;
rdfs:label "cortical preplate" ;
rdfs:comment "The layer of the developing cerebral cortex that is formed from the first cohort of neurons to migrate out of the cortical ventricular zone; split by the second wave into marginal zone and subplate." ;
rdfs:subClassOf obo:UBERON_0014950 .
obo:CHEBI_36342 a rdfs:Class ;
rdfs:label "subatomic particle" ;
rdfs:comment "A particle smaller than an atom." .
obo:GO_0015850 a rdfs:Class ;
rdfs:label "organic hydroxy compound transport" ;
rdfs:comment "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom." ;
rdfs:subClassOf obo:GO_0006810 .
obo:GO_0003358 a rdfs:Class ;
rdfs:label "noradrenergic neuron development" ;
rdfs:comment "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048666 .
obo:GO_0048850 a rdfs:Class ;
rdfs:label "hypophysis morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0022612 .
obo:GO_0002832 a rdfs:Class ;
rdfs:label "negative regulation of response to biotic stimulus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." ;
rdfs:subClassOf obo:GO_0002831 , obo:GO_0048585 , obo:GO_0065007 .
obo:PHIPO_0001186 a rdfs:Class ;
rdfs:label "obsolete functional host resistance gene present" ;
rdfs:comment "A phenotype where ability of a host to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene, is present." .
obo:UBERON_0001516 a rdfs:Class ;
rdfs:label "abdominal aorta" ;
rdfs:comment "Abdominal part of aorta: the distal part of the descending aorta, which is the continuation of the thoracic part and gives rise to the inferior phrenic, lumbar, median sacral, superior and inferior mesenteric, middle suprarenal, renal, and testicular or ovarian arteries, and celiac trunk[BTO]. The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of descending aorta(of the thorax). [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0005800 .
obo:UBERON_0000125 a rdfs:Class ;
rdfs:label "neural nucleus" ;
rdfs:comment "A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO)." ;
rdfs:subClassOf obo:UBERON_0011215 .
obo:PHIPO_0000130 a rdfs:Class ;
rdfs:label "abnormal sexual spore morphology"@en ;
rdfs:comment "A reproductive phenotype where the morphology of the sexual spore is abnormal (FAO:0000017). The product of meiosis." ;
rdfs:subClassOf obo:PHIPO_0000048 .
obo:UBERON_0006876 a rdfs:Class ;
rdfs:label "vasculature of organ" ;
rdfs:comment "A vasculature that is part of a organ." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:UBERON_0004290 a rdfs:Class ;
rdfs:label "dermomyotome" ;
rdfs:comment "The bilaminar epithelium formed from the myotome and dermatome." ;
rdfs:subClassOf obo:UBERON_0000486 , obo:UBERON_0016888 .
obo:PHIPO_0001283 a rdfs:Class ;
rdfs:label "increased host protein phosphorylation with pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, during pathogen infection occurs to a greater extent than normal (GO:0006468 protein phosphorylation)." ;
rdfs:subClassOf obo:PHIPO_0001247 .
obo:GO_1902653 a rdfs:Class ;
rdfs:label "secondary alcohol biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of secondary alcohol." ;
rdfs:subClassOf obo:GO_0046165 , obo:GO_1902652 .
obo:UBERON_0003566 a rdfs:Class ;
rdfs:label "head connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a head [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:GO_0032965 a rdfs:Class ;
rdfs:label "regulation of collagen biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0010712 , obo:GO_0065007 .
obo:CHEBI_33822 a rdfs:Class ;
rdfs:label "organic hydroxy compound" ;
rdfs:comment "An organic compound having at least one hydroxy group attached to a carbon atom." ;
rdfs:subClassOf obo:CHEBI_24651 , obo:CHEBI_50860 .
obo:PHIPO_0001362 a rdfs:Class ;
rdfs:label "resistance to isopyrazam" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to isopyrazam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000970 a rdfs:Class ;
rdfs:label "autophagosomes present in decreased numbers"@en ;
rdfs:comment "A single organism phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer autophagosomes than normal (GO:0005776)." ;
rdfs:subClassOf obo:PHIPO_0000973 .
obo:PHIPO_0000685 a rdfs:Class ;
rdfs:label "resistance to tobramycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tobramycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0098762 a rdfs:Class ;
rdfs:label "meiotic cell cycle phase" ;
rdfs:comment "One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ;
rdfs:subClassOf obo:GO_0022403 .
obo:PHIPO_0000034 a rdfs:Class ;
rdfs:label "cell phenotype" ;
rdfs:comment "A single species phenotype that is observed at the level of an individual cell." ;
rdfs:subClassOf obo:PHIPO_0000402 .
obo:GO_0006415 a rdfs:Class ;
rdfs:label "translational termination" ;
rdfs:comment "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)." ;
rdfs:subClassOf obo:GO_0032984 .
obo:GO_1904037 a rdfs:Class ;
rdfs:label "positive regulation of epithelial cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process." ;
rdfs:subClassOf obo:GO_0043065 , obo:GO_0065007 , obo:GO_1904035 .
obo:CHEBI_22479 a rdfs:Class ;
rdfs:label "amino cyclitol glycoside" ;
rdfs:subClassOf obo:CHEBI_23451 , obo:CHEBI_24400 .
obo:GO_0048771 a rdfs:Class ;
rdfs:label "tissue remodeling" ;
rdfs:comment "The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0007006 a rdfs:Class ;
rdfs:label "mitochondrial membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion." ;
rdfs:subClassOf obo:GO_0007005 , obo:GO_0061024 .
obo:GO_1905081 a rdfs:Class ;
rdfs:label "positive regulation of cerebellar neuron development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cerebellar neuron development." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0045666 , obo:GO_0065007 , obo:GO_1905079 .
obo:UBERON_0010336 a rdfs:Class ;
rdfs:label "mandibular process mesenchyme from neural crest" ;
rdfs:comment "Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0006905 , obo:UBERON_0010258 .
obo:UBERON_0004292 a rdfs:Class ;
rdfs:label "cardiac skeleton" ;
rdfs:comment "Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart." ;
rdfs:subClassOf obo:UBERON_0003837 .
obo:GO_0098739 a rdfs:Class ;
rdfs:label "import across plasma membrane" ;
rdfs:comment "The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0055085 , obo:GO_0098657 .
obo:PHIPO_0001007 a rdfs:Class ;
rdfs:label "obsolete pathogen colonization of host morphology phenotype" ;
rdfs:comment "A pathogen host interaction phenotype which affects the morphology of the pathogen or the host during pathogen colonization of the host. This relates to the pathogen colonization of the body, tissues, or cells of the host organism." .
obo:GO_0009791 a rdfs:Class ;
rdfs:label "post-embryonic development" ;
rdfs:comment "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0060413 a rdfs:Class ;
rdfs:label "atrial septum morphogenesis" ;
rdfs:comment "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060411 .
obo:GO_0005310 a rdfs:Class ;
rdfs:label "dicarboxylic acid transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." ;
rdfs:subClassOf obo:GO_0022857 , obo:GO_0046943 .
obo:UBERON_0036302 a rdfs:Class ;
rdfs:label "vasculature of central nervous system plus retina" ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:CHEBI_33308 a rdfs:Class ;
rdfs:label "carboxylic ester" ;
rdfs:comment "An ester of a carboxylic acid, R1C(=O)OR2, where R1 = H or organyl and R2 = organyl." ;
rdfs:subClassOf obo:CHEBI_35701 , obo:CHEBI_36586 .
obo:GO_0050840 a rdfs:Class ;
rdfs:label "extracellular matrix binding" ;
rdfs:comment "Binding to a component of the extracellular matrix." ;
rdfs:subClassOf obo:GO_0005488 .
obo:GO_0120278 a rdfs:Class ;
rdfs:label "negative regulation of cerebral blood circulation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120276 , obo:GO_1903523 .
obo:UBERON_0009778 a rdfs:Class ;
rdfs:label "pleural sac" ;
rdfs:comment "A serous sac that has the pleura and the pleural cavity as parts." ;
rdfs:subClassOf obo:UBERON_0005906 , obo:UBERON_0015212 .
obo:GO_0010714 a rdfs:Class ;
rdfs:label "positive regulation of collagen metabolic process" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0010712 , obo:GO_0065007 .
obo:GO_0006109 a rdfs:Class ;
rdfs:label "regulation of carbohydrate metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080090 .
obo:PHIPO_0000168 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction RNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is abnormal, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:UBERON_0029002 a rdfs:Class ;
rdfs:label "matrix compartment of putamen" ;
rdfs:subClassOf obo:UBERON_0027368 .
obo:CL_1000073 a rdfs:Class ;
rdfs:label "spinal cord radial glial cell" ;
rdfs:comment "Any radial glial cell that is part of some spinal cord." ;
rdfs:subClassOf obo:CL_0000681 .
obo:CL_0008019 a rdfs:Class ;
rdfs:label "mesenchymal cell" ;
rdfs:comment "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." ;
rdfs:subClassOf obo:CL_0000219 .
obo:CL_0000355 a rdfs:Class ;
rdfs:label "multi-potent skeletal muscle stem cell" ;
rdfs:comment "A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell." ;
rdfs:subClassOf obo:CL_0000048 , obo:CL_0000188 .
obo:GO_2000738 a rdfs:Class ;
rdfs:label "positive regulation of stem cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of stem cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0065007 , obo:GO_2000736 .
obo:GO_0048598 a rdfs:Class ;
rdfs:label "embryonic morphogenesis" ;
rdfs:comment "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_1900249 a rdfs:Class ;
rdfs:label "positive regulation of cytoplasmic translational elongation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation." ;
rdfs:subClassOf obo:GO_0045901 , obo:GO_0065007 , obo:GO_1900247 .
obo:GO_1901863 a rdfs:Class ;
rdfs:label "positive regulation of muscle tissue development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of muscle tissue development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_1901861 .
obo:GO_0030155 a rdfs:Class ;
rdfs:label "regulation of cell adhesion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:CHEBI_35475 a rdfs:Class ;
rdfs:label "non-steroidal anti-inflammatory drug" ;
rdfs:comment "An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins." ;
rdfs:subClassOf obo:CHEBI_35472 , obo:CHEBI_35842 .
obo:PHIPO_0000238 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction protein localization phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the localization of a protein in a cell." .
obo:GO_2001223 a rdfs:Class ;
rdfs:label "negative regulation of neuron migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration." ;
rdfs:subClassOf obo:GO_0030336 , obo:GO_0065007 , obo:GO_2001222 .
obo:GO_0032589 a rdfs:Class ;
rdfs:label "neuron projection membrane" ;
rdfs:comment "The portion of the plasma membrane surrounding a neuron projection." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031253 , obo:GO_0031256 .
obo:UBERON_0008998 a rdfs:Class ;
rdfs:label "vasculature of brain" ;
rdfs:comment "System pertaining to blood vessels in the brain." ;
rdfs:subClassOf obo:UBERON_0006876 , obo:UBERON_0036303 .
obo:CL_0002251 a rdfs:Class ;
rdfs:label "epithelial cell of alimentary canal" ;
rdfs:comment "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002076 .
obo:PATO_0002302 a rdfs:Class ;
rdfs:label "decreased process quality" ;
rdfs:comment "A quality of a process that has a value that is decreased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0001236 , obo:PATO_0002301 .
obo:GO_0045580 a rdfs:Class ;
rdfs:label "regulation of T cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of T cell differentiation." ;
rdfs:subClassOf obo:GO_0045619 , obo:GO_0050863 , obo:GO_0065007 .
obo:CHEBI_36233 a rdfs:Class ;
rdfs:label "disaccharide" ;
rdfs:comment "A compound in which two monosaccharides are joined by a glycosidic bond." ;
rdfs:subClassOf obo:CHEBI_50699 .
obo:PATO_0001163 a rdfs:Class ;
rdfs:label "decreased concentration" ;
rdfs:comment "A concentration which is lower relative to the normal or average." ;
rdfs:subClassOf obo:PATO_0001159 , obo:PATO_0001997 , obo:PATO_0002303 .
obo:CHEBI_38260 a rdfs:Class ;
rdfs:label "pyrrolidines" ;
rdfs:comment "Any of a class of heterocyclic amines having a saturated five-membered ring." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:PHIPO_0001208 a rdfs:Class ;
rdfs:label "unicellular colony morphology phenotype"@en ;
rdfs:comment "A single species population phenotype affecting the morphology of a colony of unicellular individuals." ;
rdfs:subClassOf obo:PHIPO_0000509 .
obo:UBERON_0001943 a rdfs:Class ;
rdfs:label "midbrain tegmentum" ;
rdfs:comment "Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:PHIPO_0001154 a rdfs:Class ;
rdfs:label "decreased pathogen chitin fragment binding"@en ;
rdfs:comment "A single species pathogen molecular function phenotype in which pathogen chitin fragment binding by a pathogen gene product is decreased." ;
rdfs:subClassOf obo:PHIPO_0000423 .
obo:GO_0021654 a rdfs:Class ;
rdfs:label "rhombomere boundary formation" ;
rdfs:comment "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." ;
rdfs:subClassOf obo:GO_0048646 , obo:GO_0048859 .
obo:GO_0046671 a rdfs:Class ;
rdfs:label "negative regulation of retinal cell programmed cell death" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina." ;
rdfs:subClassOf obo:GO_0043069 , obo:GO_0046668 , obo:GO_0051093 , obo:GO_0065007 .
obo:CHEBI_23906 a rdfs:Class ;
rdfs:label "monoatomic cation" ;
rdfs:subClassOf obo:CHEBI_24867 , obo:CHEBI_36916 .
obo:UBERON_0011919 a rdfs:Class ;
rdfs:label "yolk sac blood island" ;
rdfs:comment "Masses of developing blood cells attached to endothelium in the yolk sac." ;
rdfs:subClassOf obo:UBERON_0000478 , obo:UBERON_0003061 .
obo:GO_0000272 a rdfs:Class ;
rdfs:label "polysaccharide catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ;
rdfs:subClassOf obo:GO_0005976 , obo:GO_0009056 , obo:GO_0009057 , obo:GO_0016052 .
obo:CHEBI_55517 a rdfs:Class ;
rdfs:label "trichothecene" ;
rdfs:comment "Any one of a large family of chemically related mycotoxins with a structure based on a sesquiterpene skeleton. The most important structural features causing the biological activities of trichothecenes are a 12,13-epoxy ring, the presence of hydroxy or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain." ;
rdfs:subClassOf obo:CHEBI_26658 , obo:CHEBI_32955 , obo:CHEBI_38166 .
obo:UBERON_0005629 a rdfs:Class ;
rdfs:label "vascular plexus" ;
rdfs:comment "A vascular network formed by frequent anastomoses between the blood vessels (arteries or veins) of a part." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:UBERON_0010343 a rdfs:Class ;
rdfs:label "2nd arch mesenchyme from head mesenchyme" ;
rdfs:comment "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 2nd arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005689 , obo:UBERON_0010360 .
obo:GO_0032984 a rdfs:Class ;
rdfs:label "protein-containing complex disassembly" ;
rdfs:comment "The disaggregation of a protein-containing macromolecular complex into its constituent components." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0043933 .
obo:PHIPO_0001425 a rdfs:Class ;
rdfs:label "normal growth on imazalil" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to imazalil (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0003032 a rdfs:Class ;
rdfs:label "detection of oxygen" ;
rdfs:comment "The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0009593 , obo:GO_0070482 .
obo:GO_1900126 a rdfs:Class ;
rdfs:label "negative regulation of hyaluronan biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process." ;
rdfs:subClassOf obo:GO_0010558 , obo:GO_0045912 , obo:GO_0065007 , obo:GO_1900125 .
obo:GO_0043068 a rdfs:Class ;
rdfs:label "positive regulation of programmed cell death" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0048522 , obo:GO_0065007 .
obo:CHEBI_50335 a rdfs:Class ;
rdfs:label "organic nitrogen anion" ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_35352 .
obo:GO_0044065 a rdfs:Class ;
rdfs:label "regulation of respiratory system process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system." ;
rdfs:subClassOf obo:GO_0043576 , obo:GO_0044057 , obo:GO_0065007 .
obo:GO_0060532 a rdfs:Class ;
rdfs:label "bronchus cartilage development" ;
rdfs:comment "The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0051216 .
obo:CHEBI_8269 a rdfs:Class ;
rdfs:label "Pleuromutilin" ;
rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_38032 , obo:CHEBI_3992 .
obo:GO_0086018 a rdfs:Class ;
rdfs:label "SA node cell to atrial cardiac muscle cell signaling" ;
rdfs:comment "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte." ;
rdfs:subClassOf obo:GO_0086070 .
obo:GO_1905153 a rdfs:Class ;
rdfs:label "regulation of membrane invagination" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of membrane invagination." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:CL_0002333 a rdfs:Class ;
rdfs:label "neural crest derived adipocyte" ;
rdfs:comment "An adipocyte derived from a neural crest cell." ;
rdfs:subClassOf obo:CL_0000136 .
obo:GO_0019233 a rdfs:Class ;
rdfs:label "sensory perception of pain" ;
rdfs:comment "The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. A painful stimulus is any physical or chemical event that has the potential to cause tissue damage (actual or perceived) and activates the nociceptive system." ;
rdfs:subClassOf obo:GO_0007600 .
obo:GO_0051147 a rdfs:Class ;
rdfs:label "regulation of muscle cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:GO_1905269 a rdfs:Class ;
rdfs:label "positive regulation of chromatin organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of chromatin organization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902275 , obo:GO_2001252 .
obo:GO_0021697 a rdfs:Class ;
rdfs:label "cerebellar cortex formation" ;
rdfs:comment "The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0071672 a rdfs:Class ;
rdfs:label "negative regulation of smooth muscle cell chemotaxis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis." ;
rdfs:subClassOf obo:GO_0014912 , obo:GO_0050922 , obo:GO_0065007 , obo:GO_0071671 .
obo:GO_0015075 a rdfs:Class ;
rdfs:label "monoatomic ion transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of an ion from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 .
obo:CHEBI_30804 a rdfs:Class ;
rdfs:label "isophthalate(1-)" ;
rdfs:comment "A dicarboxylic acid monoanion that is the conjugate base of isophthalic acid." ;
rdfs:subClassOf obo:CHEBI_35695 .
obo:CL_0010007 a rdfs:Class ;
rdfs:label "His-Purkinje system cell" ;
rdfs:comment "Any cell that is part of some His-Purkinje system." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0002494 .
obo:GO_0098988 a rdfs:Class ;
rdfs:label "G protein-coupled glutamate receptor activity" ;
rdfs:comment "Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity." ;
rdfs:subClassOf obo:GO_0004930 , obo:GO_0008066 .
obo:GO_0007418 a rdfs:Class ;
rdfs:label "ventral midline development" ;
rdfs:comment "The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate." ;
rdfs:subClassOf obo:GO_0048856 .
obo:PHIPO_0000276 a rdfs:Class ;
rdfs:label "normal tissue phenotype"@en ;
rdfs:comment "A phenotype that does not show any detectable differences from normal at the level of a tissue (eg leaf, inflorescence, ear or kidney)." ;
rdfs:subClassOf obo:PHIPO_0000003 .
obo:GO_0086068 a rdfs:Class ;
rdfs:label "Purkinje myocyte to ventricular cardiac muscle cell communication" ;
rdfs:comment "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0086065 .
obo:GO_0031594 a rdfs:Class ;
rdfs:label "neuromuscular junction" ;
rdfs:comment "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." ;
rdfs:subClassOf obo:GO_0045202 .
obo:UBERON_0002359 a rdfs:Class ;
rdfs:label "fibrous pericardium" ;
rdfs:comment "Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000094 , obo:UBERON_0005181 .
obo:PHIPO_0000542 a rdfs:Class ;
rdfs:label "resistance to ethambutol"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ethambutol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PATO_0002078 a rdfs:Class ;
rdfs:label "hollow" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's having an empty space or cavity within." ;
rdfs:subClassOf obo:PATO_0002014 .
obo:GO_2000794 a rdfs:Class ;
rdfs:label "regulation of epithelial cell proliferation involved in lung morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." ;
rdfs:subClassOf obo:GO_0050678 , obo:GO_0065007 .
obo:GO_0021691 a rdfs:Class ;
rdfs:label "cerebellar Purkinje cell layer maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:GO_0030447 a rdfs:Class ;
rdfs:label "filamentous growth" ;
rdfs:comment "The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape." ;
rdfs:subClassOf obo:GO_0040007 .
obo:GO_0055002 a rdfs:Class ;
rdfs:label "striated muscle cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0055001 .
obo:CHEBI_50646 a rdfs:Class ;
rdfs:label "bone density conservation agent" ;
rdfs:comment "An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0050942 a rdfs:Class ;
rdfs:label "positive regulation of pigment cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0048087 , obo:GO_0050932 , obo:GO_0065007 .
obo:GO_0008078 a rdfs:Class ;
rdfs:label "mesodermal cell migration" ;
rdfs:comment "The orderly movement of mesodermal cells from one site to another." ;
rdfs:subClassOf obo:GO_0001667 , obo:GO_0016477 .
obo:PATO_0001650 a rdfs:Class ;
rdfs:label "increased resistance to" ;
rdfs:comment "A resistance to a stimulus which is relatively high." ;
rdfs:subClassOf obo:PATO_0001178 , obo:PATO_0002305 .
obo:PHIPO_0001095 a rdfs:Class ;
rdfs:label "abnormal localization of chitin in cell"@en ;
rdfs:comment "A single organism phenotype in which the localization of chitin in a cell is abnormal. Chitin may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." ;
rdfs:subClassOf obo:PHIPO_0001094 .
obo:GO_0048193 a rdfs:Class ;
rdfs:label "Golgi vesicle transport" ;
rdfs:comment "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles." ;
rdfs:subClassOf obo:GO_0016192 .
obo:PHIPO_0000416 a rdfs:Class ;
rdfs:label "normal molecular function"@en ;
rdfs:comment "A phenotype in which a specific molecular function is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000411 .
obo:UBERON_0004537 a rdfs:Class ;
rdfs:label "blood vasculature" ;
rdfs:comment "A vascular network consisting of blood vessels." ;
rdfs:subClassOf obo:UBERON_0002049 .
obo:UBERON_0002196 a rdfs:Class ;
rdfs:label "adenohypophysis" ;
rdfs:comment "The glandular, anterior lobe of the pituitary gland. The anterior pituitary regulates several physiological processes including stress, growth, and reproduction[WP]. The anterior lobe of the hypophysis (pituitary gland). This lobe contains cells that produce prolactin, growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone and proopiomelanocortin[ZFA]." ;
rdfs:subClassOf obo:UBERON_0000064 , obo:UBERON_0004121 , obo:UBERON_0005156 .
obo:GO_0051954 a rdfs:Class ;
rdfs:label "positive regulation of amine transport" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051050 , obo:GO_0051952 , obo:GO_0065007 .
obo:UBERON_0003505 a rdfs:Class ;
rdfs:label "trachea blood vessel" ;
rdfs:comment "A blood vessel that is part of a trachea." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003504 .
obo:GO_0099523 a rdfs:Class ;
rdfs:label "presynaptic cytosol" ;
rdfs:comment "The region of the cytosol consisting of all cytosol that is part of the presynapse." ;
rdfs:subClassOf obo:GO_0005829 .
obo:PHIPO_0000287 a rdfs:Class ;
rdfs:label "increased cellular pigment accumulation"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of coloring matter in a cell is increased." ;
rdfs:subClassOf obo:PHIPO_0000285 , obo:PHIPO_0000929 .
obo:CHEBI_36043 a rdfs:Class ;
rdfs:label "antimicrobial drug" ;
rdfs:comment "A drug used to treat or prevent microbial infections." ;
rdfs:subClassOf obo:CHEBI_33281 , obo:CHEBI_35441 .
obo:GO_0051633 a rdfs:Class ;
rdfs:label "positive regulation of acetylcholine uptake" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell." ;
rdfs:subClassOf obo:GO_0051631 , obo:GO_0051954 , obo:GO_0065007 .
obo:GO_0006955 a rdfs:Class ;
rdfs:label "immune response" ;
rdfs:comment "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0050896 .
obo:CHEBI_38181 a rdfs:Class ;
rdfs:label "pyridinemonocarboxylate" ;
rdfs:comment "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of a pyridinemonocarboxylic acid. A 'closed class'." ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:PHIPO_0000943 a rdfs:Class ;
rdfs:label "sensitive to hydrogen peroxide"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to hydrogen peroxide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 , obo:PHIPO_0001398 .
obo:GO_1904410 a rdfs:Class ;
rdfs:label "negative regulation of secretory granule organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0065007 , obo:GO_1904409 .
obo:UBERON_0007239 a rdfs:Class ;
rdfs:label "tunica media of artery" ;
rdfs:comment "A tunica media that is part of a artery." ;
rdfs:subClassOf obo:UBERON_0002522 .
obo:GO_0061047 a rdfs:Class ;
rdfs:label "positive regulation of branching involved in lung morphogenesis" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." ;
rdfs:subClassOf obo:GO_0051240 , obo:GO_0061046 , obo:GO_0065007 , obo:GO_1905332 .
obo:GO_2001251 a rdfs:Class ;
rdfs:label "negative regulation of chromosome organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization." ;
rdfs:subClassOf obo:GO_0010639 , obo:GO_0033044 , obo:GO_0065007 .
obo:GO_0002821 a rdfs:Class ;
rdfs:label "positive regulation of adaptive immune response" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response." ;
rdfs:subClassOf obo:GO_0002819 , obo:GO_0050778 , obo:GO_0065007 .
obo:GO_0097355 a rdfs:Class ;
rdfs:label "protein localization to heterochromatin" ;
rdfs:comment "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0071168 .
obo:GO_0032945 a rdfs:Class ;
rdfs:label "negative regulation of mononuclear cell proliferation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation." ;
rdfs:subClassOf obo:GO_0032944 , obo:GO_0065007 , obo:GO_0070664 .
obo:CL_4023097 a rdfs:Class ;
rdfs:label "arachnoid barrier cell" ;
rdfs:comment "A mesothelial fibroblast of the arachnoid barrier layer. Arachnoid barrier cells make up the tight-junctioned layer in the leptomeninx that functions as the physiologic barrier between the cerebrospinal fluid in the subarachnoid space and the fenestrated capillaries in the dura." ;
rdfs:subClassOf obo:CL_4023058 .
obo:UBERON_0003500 a rdfs:Class ;
rdfs:label "corneal blood vessel" ;
rdfs:comment "A blood vessel that is part of a cornea [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003496 .
obo:CHEBI_59740 a rdfs:Class ;
rdfs:label "nucleophilic reagent" ;
rdfs:comment "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." ;
rdfs:subClassOf obo:CHEBI_33893 , obo:CHEBI_39144 .
obo:UBERON_0002469 a rdfs:Class ;
rdfs:label "esophagus mucosa" ;
rdfs:comment "A mucosa that is part of a esophagus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000344 .
obo:GO_0002697 a rdfs:Class ;
rdfs:label "regulation of immune effector process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of an immune effector process." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0065007 .
obo:UBERON_0002062 a rdfs:Class ;
rdfs:label "endocardial cushion" ;
rdfs:comment "The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005256 , obo:UBERON_0009751 , obo:UBERON_0014387 .
obo:PHIPO_0000152 a rdfs:Class ;
rdfs:label "abnormal RNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is abnormal, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000142 , obo:PHIPO_0000413 .
obo:GO_0034767 a rdfs:Class ;
rdfs:label "positive regulation of monoatomic ion transmembrane transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0034764 , obo:GO_0034765 , obo:GO_0043270 , obo:GO_0065007 .
obo:CHEBI_48376 a rdfs:Class ;
rdfs:label "carbamimidic acid" ;
rdfs:subClassOf obo:CHEBI_48379 , obo:CHEBI_64708 .
obo:UBERON_0011772 a rdfs:Class ;
rdfs:label "lower jaw opening" ;
rdfs:comment "An anatomical space that is part of a bone of lower jaw." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:PHIPO_0001414 a rdfs:Class ;
rdfs:label "resistance to thifluzamide" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to thifluzamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0035694 a rdfs:Class ;
rdfs:label "mitochondrial protein catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure." ;
rdfs:subClassOf obo:GO_0030163 .
obo:GO_1901210 a rdfs:Class ;
rdfs:label "regulation of cardiac chamber formation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac chamber formation." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0060785 a rdfs:Class ;
rdfs:label "regulation of apoptosis involved in tissue homeostasis" ;
rdfs:comment "Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue." ;
rdfs:subClassOf obo:GO_0042981 .
obo:GO_1905460 a rdfs:Class ;
rdfs:label "negative regulation of vascular associated smooth muscle cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." ;
rdfs:subClassOf obo:GO_0034392 , obo:GO_0065007 , obo:GO_1905459 .
obo:GO_0010481 a rdfs:Class ;
rdfs:label "epidermal cell division" ;
rdfs:comment "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells." ;
rdfs:subClassOf obo:GO_0051301 .
obo:GO_0002762 a rdfs:Class ;
rdfs:label "negative regulation of myeloid leukocyte differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation." ;
rdfs:subClassOf obo:GO_0002761 , obo:GO_0045638 , obo:GO_0065007 , obo:GO_1902106 .
obo:GO_1903903 a rdfs:Class ;
rdfs:label "regulation of establishment of T cell polarity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of establishment of T cell polarity." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000114 .
obo:GO_1990048 a rdfs:Class ;
rdfs:label "anterograde neuronal dense core vesicle transport" ;
rdfs:comment "The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0008089 , obo:GO_0047496 , obo:GO_0099519 .
obo:GO_0048636 a rdfs:Class ;
rdfs:label "positive regulation of muscle organ development" ;
rdfs:comment "Any process that activates, maintains or increases the rate of muscle development." ;
rdfs:subClassOf obo:GO_0048634 , obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0001654 a rdfs:Class ;
rdfs:label "eye development" ;
rdfs:comment "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight." ;
rdfs:subClassOf obo:GO_0007423 , obo:GO_0048856 .
obo:GO_0003229 a rdfs:Class ;
rdfs:label "ventricular cardiac muscle tissue development" ;
rdfs:comment "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048738 , obo:GO_0048856 .
obo:GO_0021795 a rdfs:Class ;
rdfs:label "cerebral cortex cell migration" ;
rdfs:comment "The orderly movement of cells from one site to another in the cerebral cortex." ;
rdfs:subClassOf obo:GO_0022029 .
obo:CHEBI_38102 a rdfs:Class ;
rdfs:label "triazines" ;
rdfs:comment "Compounds based on a triazine skeleton." ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_50893 .
obo:UBERON_0005291 a rdfs:Class ;
rdfs:label "embryonic tissue" ;
rdfs:comment "A portion of tissue that is part of an embryo." ;
rdfs:subClassOf obo:UBERON_0000479 .
obo:CHEBI_35555 a rdfs:Class ;
rdfs:label "mancude organic heteromonocyclic parent" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_35571 .
obo:GO_0035992 a rdfs:Class ;
rdfs:label "tendon formation" ;
rdfs:comment "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0002532 a rdfs:Class ;
rdfs:label "production of molecular mediator involved in inflammatory response" ;
rdfs:comment "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0042129 a rdfs:Class ;
rdfs:label "regulation of T cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of T cell proliferation." ;
rdfs:subClassOf obo:GO_0050670 , obo:GO_0050863 , obo:GO_0065007 .
obo:PHIPO_0001378 a rdfs:Class ;
rdfs:label "resistance to tacrolimus" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tacrolimus. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_2000044 a rdfs:Class ;
rdfs:label "brain microvascular endothelial cell" ;
rdfs:comment "Any microvascular endothelial cell that is part of a brain." ;
rdfs:subClassOf obo:CL_0002319 , obo:CL_2000008 .
obo:UBERON_0014777 a rdfs:Class ;
rdfs:label "spinal neuromere" ;
rdfs:comment "A neuromere that is part of the presumptive spinal cord." ;
rdfs:subClassOf obo:UBERON_0004731 .
obo:GO_0002227 a rdfs:Class ;
rdfs:label "innate immune response in mucosa" ;
rdfs:comment "Any process of the innate immune response that takes place in the mucosal tissues." ;
rdfs:subClassOf obo:GO_0002385 , obo:GO_0045087 .
obo:GO_1903975 a rdfs:Class ;
rdfs:label "regulation of glial cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glial cell migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:GO_0014054 a rdfs:Class ;
rdfs:label "positive regulation of gamma-aminobutyric acid secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." ;
rdfs:subClassOf obo:GO_0014052 , obo:GO_0032892 , obo:GO_0051047 , obo:GO_0051957 , obo:GO_0065007 .
obo:GO_2001014 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:UBERON_0001974 a rdfs:Class ;
rdfs:label "lamina propria of esophagus" ;
rdfs:comment "A lamina propria that is part of a esophagus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000030 .
obo:PHIPO_0001074 a rdfs:Class ;
rdfs:label "sensitive to iron ion starvation"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to iron ion starvation. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide." ;
rdfs:subClassOf obo:PHIPO_0001098 .
a rdfs:Class ;
rdfs:label "retina" ;
rdfs:subClassOf , obo:UBERON_0000966 .
obo:GO_2000402 a rdfs:Class ;
rdfs:label "negative regulation of lymphocyte migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0071676 , obo:GO_2000401 .
obo:GO_0042446 a rdfs:Class ;
rdfs:label "hormone biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0042445 .
obo:CL_0010022 a rdfs:Class ;
rdfs:label "cardiac neuron" ;
rdfs:comment "A neuron that has its soma in the heart." ;
rdfs:subClassOf obo:CL_2000032 .
obo:GO_0009084 a rdfs:Class ;
rdfs:label "glutamate family amino acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of L-glutamate or any of the amino acids synthesised from it (L-glutamine, L-proline and L-arginine)." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0170034 , obo:GO_0170038 .
obo:GO_2001206 a rdfs:Class ;
rdfs:label "positive regulation of osteoclast development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of osteoclast development." ;
rdfs:subClassOf obo:GO_0045672 , obo:GO_0065007 , obo:GO_2001204 .
obo:GO_0072091 a rdfs:Class ;
rdfs:label "regulation of stem cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:GO_0045834 a rdfs:Class ;
rdfs:label "positive regulation of lipid metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." ;
rdfs:subClassOf obo:GO_0009893 , obo:GO_0019216 , obo:GO_0065007 .
obo:PHIPO_0000269 a rdfs:Class ;
rdfs:label "normal protein localization"@en ;
rdfs:comment "A single organism phenotype in which the localization of a protein in a cell is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000237 .
obo:CL_4310096 a rdfs:Class ;
rdfs:label "GPi Shell internal globus pallidus shell projection neuron (Primate)" ;
rdfs:comment "A internal globus pallidus shell projection neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus, internal segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPi Shell." ;
rdfs:subClassOf obo:CL_0020004 .
obo:GO_1904338 a rdfs:Class ;
rdfs:label "regulation of dopaminergic neuron differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation." ;
rdfs:subClassOf obo:GO_0045664 , obo:GO_0065007 .
obo:PATO_0001857 a rdfs:Class ;
rdfs:label "concave" ;
rdfs:comment "A shape quality in a bearer by virtue of the bearer's curving inward." ;
rdfs:subClassOf obo:PATO_0002005 .
obo:GO_0060491 a rdfs:Class ;
rdfs:label "regulation of cell projection assembly" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of cell projection assembly." ;
rdfs:subClassOf obo:GO_0031344 , obo:GO_0044087 , obo:GO_0065007 .
obo:GO_0060562 a rdfs:Class ;
rdfs:label "epithelial tube morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." ;
rdfs:subClassOf obo:GO_0002009 , obo:GO_0009653 , obo:GO_0035239 .
obo:UBERON_0003134 a rdfs:Class ;
rdfs:label "female reproductive organ" ;
rdfs:comment "A female organ involved in reproduction." ;
rdfs:subClassOf obo:UBERON_0003133 .
obo:CHEBI_61774 a rdfs:Class ;
rdfs:label "inositol phosphorylceramide synthase inhibitor" ;
rdfs:comment "An enzyme inhibitor that inhibits the action of inositol phosphorylceramide synthase." ;
rdfs:subClassOf obo:CHEBI_76881 .
obo:UBERON_0007845 a rdfs:Class ;
rdfs:label "regular connective tissue" ;
rdfs:comment "Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:UBERON_0006566 a rdfs:Class ;
rdfs:label "left ventricle myocardium" ;
rdfs:comment "A myocardium that is part of a left ventricle of a heart." ;
rdfs:subClassOf obo:UBERON_0001083 .
obo:GO_0022029 a rdfs:Class ;
rdfs:label "telencephalon cell migration" ;
rdfs:comment "The orderly movement of a cell from one site to another at least one of which is located in the telencephalon." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0021885 .
obo:UBERON_0007099 a rdfs:Class ;
rdfs:label "hyoid neural crest" ;
rdfs:comment "Cranial neural crest that migrates into the hyoid arch." ;
rdfs:subClassOf obo:UBERON_0003099 .
obo:CHEBI_24868 a rdfs:Class ;
rdfs:label "organic salt" ;
rdfs:subClassOf obo:CHEBI_24866 .
obo:PHIPO_0000902 a rdfs:Class ;
rdfs:label "sensitive to sparfloxacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to sparfloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0010626 a rdfs:Class ;
rdfs:label "negative regulation of Schwann cell proliferation" ;
rdfs:comment "Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." ;
rdfs:subClassOf obo:GO_0010624 , obo:GO_0060253 , obo:GO_0065007 .
obo:PHIPO_0000854 a rdfs:Class ;
rdfs:label "sensitive to gramicidin D"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to gramicidin D. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0021515 a rdfs:Class ;
rdfs:label "cell differentiation in spinal cord" ;
rdfs:comment "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0030154 .
obo:CL_4310128 a rdfs:Class ;
rdfs:label "STRd Cholinergic GABA dorso-striatal cholinergic-GABAergic neuron (Primate)" ;
rdfs:comment "A dorso-striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd Cholinergic GABA." ;
rdfs:subClassOf obo:CL_0020007 .
obo:CL_0000553 a rdfs:Class ;
rdfs:label "megakaryocyte progenitor cell" ;
rdfs:comment "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." ;
rdfs:subClassOf obo:CL_0000763 , obo:CL_0000839 .
obo:UBERON_0011362 a rdfs:Class ;
rdfs:label "cranial blood vasculature" ;
rdfs:comment "A blood vasculature that is part of a head." ;
rdfs:subClassOf obo:UBERON_0002200 , obo:UBERON_0004537 .
obo:PHIPO_0001261 a rdfs:Class ;
rdfs:label "host cell inviable with pathogen"@en ;
rdfs:comment "A host cell viability phenotype where the host cell death is accelerated by the pathogen." ;
rdfs:subClassOf obo:PHIPO_0001259 .
obo:CHEBI_33303 a rdfs:Class ;
rdfs:label "chalcogen" ;
rdfs:comment "Any p-block element belonging to the group 16 family of the periodic table." ;
rdfs:subClassOf obo:CHEBI_33560 .
obo:GO_0009707 a rdfs:Class ;
rdfs:label "chloroplast outer membrane" ;
rdfs:comment "The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope." ;
rdfs:subClassOf obo:GO_0009527 , obo:GO_0016020 , obo:GO_0031969 .
obo:GO_0060348 a rdfs:Class ;
rdfs:label "bone development" ;
rdfs:comment "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components." ;
rdfs:subClassOf obo:GO_0048513 .
obo:UBERON_0005082 a rdfs:Class ;
rdfs:label "tube lumen" ;
rdfs:comment "A hole in a tube[GO]." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:UBERON_0000924 a rdfs:Class ;
rdfs:label "ectoderm" ;
rdfs:comment "Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue." ;
rdfs:subClassOf obo:UBERON_0000923 .
obo:CHEBI_62872 a rdfs:Class ;
rdfs:label "EC 1.2.3.1 (aldehyde oxidase) inhibitor" ;
rdfs:comment "An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1)." ;
rdfs:subClassOf obo:CHEBI_76853 .
obo:UBERON_0000072 a rdfs:Class ;
rdfs:label "proximo-distal subdivision of respiratory tract" ;
rdfs:comment "An section of a respiratory tract." ;
rdfs:subClassOf obo:UBERON_0013522 .
obo:PR_P10810 a rdfs:Class ;
rdfs:label "monocyte differentiation antigen CD14 (mouse)" ;
rdfs:comment "A CD14 molecule that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001889 , obo:PR_000029032 .
obo:GO_0034613 a rdfs:Class .
obo:GO_0035907 a rdfs:Class ;
rdfs:label "dorsal aorta development" ;
rdfs:comment "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." ;
rdfs:subClassOf obo:GO_0035904 , obo:GO_0048856 .
obo:CL_0000023 a rdfs:Class ;
rdfs:label "oocyte" ;
rdfs:comment "A female germ cell that has entered meiosis." ;
rdfs:subClassOf obo:CL_0000021 .
obo:GO_0110124 a rdfs:Class ;
rdfs:label "positive regulation of myotube cell migration" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration." ;
rdfs:subClassOf obo:GO_0030335 , obo:GO_0065007 , obo:GO_0110123 .
obo:CHEBI_30412 a rdfs:Class ;
rdfs:label "monoatomic dication" ;
rdfs:subClassOf obo:CHEBI_23906 .
obo:UBERON_0005946 a rdfs:Class ;
rdfs:label "outflow tract of atrium" ;
rdfs:comment "An outflow tract that is part of a cardiac atrium." ;
rdfs:subClassOf obo:UBERON_0004145 .
obo:CHEBI_36335 a rdfs:Class ;
rdfs:label "trypanocidal drug" ;
rdfs:comment "A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida." ;
rdfs:subClassOf obo:CHEBI_35820 .
obo:UBERON_0004799 a rdfs:Class ;
rdfs:label "trachea basal lamina" ;
rdfs:comment "A basal lamina that is part of a respiratory airway [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000482 , obo:UBERON_0004798 .
obo:CL_0002194 a rdfs:Class ;
rdfs:label "monopoietic cell" ;
rdfs:comment "A cell involved in the formation of a monocyte (monopoiesis)." ;
rdfs:subClassOf obo:CL_0000839 .
obo:PHIPO_0001029 a rdfs:Class ;
rdfs:label "abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm"@en ;
rdfs:comment "A single organism phenotype in which the localization of a protein to the plasma membrane is abolished, and the protein is present in the cytoplasm instead." ;
rdfs:subClassOf obo:PHIPO_0001028 .
obo:GO_1902866 a rdfs:Class ;
rdfs:label "regulation of retina development in camera-type eye" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of retina development in camera-type eye." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_1905304 a rdfs:Class ;
rdfs:label "regulation of cardiac myofibril assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac myofibril assembly." ;
rdfs:subClassOf obo:GO_0060284 , obo:GO_0065007 , obo:GO_0110020 , obo:GO_1902115 , obo:GO_1902903 .
obo:GO_0048872 a rdfs:Class ;
rdfs:label "homeostasis of number of cells" ;
rdfs:comment "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells." ;
rdfs:subClassOf obo:GO_0048871 .
obo:GO_1900121 a rdfs:Class ;
rdfs:label "negative regulation of receptor binding" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor." ;
rdfs:subClassOf obo:GO_0032091 , obo:GO_0065007 , obo:GO_1900120 .
obo:CL_0000030 a rdfs:Class ;
rdfs:label "glioblast" ;
rdfs:comment "A non-terminally differentiated cell that develops from the neuroectoderm. Glioblast has the potential to differentiate into various types of glial cells, including astrocytes and oligodendrocytes." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0011026 .
obo:CHEBI_76759 a rdfs:Class ;
rdfs:label "EC 3.* (hydrolase) inhibitor" ;
rdfs:comment "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:PHIPO_0000002 a rdfs:Class ;
rdfs:label "single species phenotype" ;
rdfs:comment "Any of the set of observable characteristics of a single organism resulting from the interaction of its genotype with the environment." ;
rdfs:subClassOf obo:PHIPO_0000505 .
obo:GO_0010256 a rdfs:Class ;
rdfs:label "endomembrane system organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." ;
rdfs:subClassOf obo:GO_0016043 .
obo:GO_2000199 a rdfs:Class ;
rdfs:label "positive regulation of ribonucleoprotein complex localization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0065007 , obo:GO_2000197 .
obo:GO_0001932 a rdfs:Class ;
rdfs:label "regulation of protein phosphorylation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein." ;
rdfs:subClassOf obo:GO_0031399 , obo:GO_0042325 , obo:GO_0065007 .
obo:PHIPO_0000023 a rdfs:Class ;
rdfs:label "obsolete abnormal penetration assay phenotype" ;
rdfs:comment "A pathogen penetration assay phenotype (assessing the organism's ability to penetrate a given substance/membrane) which is abnormal (i.e. different than wild-type)." .
obo:GO_0097252 a rdfs:Class ;
rdfs:label "oligodendrocyte apoptotic process" ;
rdfs:comment "Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0034349 .
obo:GO_1901191 a rdfs:Class ;
rdfs:label "negative regulation of formation of translation initiation ternary complex" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex." ;
rdfs:subClassOf obo:GO_0031333 , obo:GO_0045947 , obo:GO_0065007 , obo:GO_1901190 .
obo:GO_0060981 a rdfs:Class ;
rdfs:label "cell migration involved in coronary angiogenesis" ;
rdfs:comment "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0060973 .
obo:PHIPO_0000360 a rdfs:Class ;
rdfs:label "increased pathogen penetration into host"@en ;
rdfs:comment "A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism is increased." ;
rdfs:subClassOf obo:PHIPO_0000331 .
obo:PHIPO_0000169 a rdfs:Class ;
rdfs:label "obsolete chlorosis absent" .
obo:CHEBI_134179 a rdfs:Class ;
rdfs:label "volatile organic compound" ;
rdfs:comment "Any organic compound having an initial boiling point less than or equal to 250 °C (482 °F) measured at a standard atmospheric pressure of 101.3 kPa." ;
rdfs:subClassOf obo:CHEBI_72695 .
obo:CL_4310059 a rdfs:Class ;
rdfs:label "STR D2 MSN indirect pathway medium spiny neuron (Primate)" ;
rdfs:comment "A indirect pathway medium spiny neuron of the Primates brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Subclass:STR D2 MSN." ;
rdfs:subClassOf obo:CL_4023029 .
obo:CHEBI_26833 a rdfs:Class ;
rdfs:label "sulfur atom" ;
rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33303 .
obo:UBERON_0006668 a rdfs:Class ;
rdfs:label "carotid canal" ;
rdfs:comment "On the interior surface of the temporal bone, behind the rough surface of the apex, is the large circular aperture of the carotid canal, which ascends at first vertically, and then, making a bend, runs horizontally forward and medialward. It transmits into the cranium, the internal carotid artery, and the carotid plexus of nerves. Sympathetics to the head also pass through the carotid canal. They have several motor functions: raise the eyelid (superior tarsal muscle), dilate pupil, innervate sweat glands of face and scalp and constricts blood vessels in head[WP]." ;
rdfs:subClassOf obo:UBERON_0013685 .
obo:PHIPO_0000674 a rdfs:Class ;
rdfs:label "resistance to chlortetracycline"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to chlortetracycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0071840 a rdfs:Class ;
rdfs:label "cellular component organization or biogenesis" ;
rdfs:comment "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." ;
rdfs:subClassOf obo:GO_0009987 .
obo:CHEBI_78128 a rdfs:Class ;
rdfs:label "fatty acid anion 24:0" ;
rdfs:comment "Any saturated fatty acid anion containing 24 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_58953 .
obo:UBERON_0005425 a rdfs:Class ;
rdfs:label "presumptive neural retina" ;
rdfs:comment "Portion of tissue that is the inner layer of the optic cup and will become the neural retina." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:CHEBI_77853 a rdfs:Class ;
rdfs:label "persistent organic pollutant" ;
rdfs:comment "Any environmental contaminant that is resistant to environmental degradation through photolytic, biological or chemical processes. Such substances can have significant impact on health and the environment, as they persist in the environment, bioaccumulate in animal tissue and so biomagnify in food chains." ;
rdfs:subClassOf obo:CHEBI_78298 .
obo:UBERON_0010912 a rdfs:Class ;
rdfs:label "subdivision of skeleton" ;
rdfs:comment "Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:PHIPO_0000954 a rdfs:Class ;
rdfs:label "presence of pathogen growth within host"@en ;
rdfs:comment "A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is present." ;
rdfs:subClassOf obo:PHIPO_0000951 .
obo:UBERON_0000463 a rdfs:Class ;
rdfs:label "organism substance" ;
rdfs:comment "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." ;
rdfs:subClassOf obo:UBERON_0000001 .
obo:CHEBI_26819 a rdfs:Class ;
rdfs:label "sulfuric ester" ;
rdfs:comment "An ester of an alcohol and sulfuric acid." ;
rdfs:subClassOf obo:CHEBI_35701 , obo:CHEBI_37826 .
obo:GO_0061036 a rdfs:Class ;
rdfs:label "positive regulation of cartilage development" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0061035 , obo:GO_0065007 .
obo:UBERON_0003548 a rdfs:Class ;
rdfs:label "forebrain meninges" ;
rdfs:comment "A meninx that is part of a forebrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002360 , obo:UBERON_0003547 .
obo:PHIPO_0000549 a rdfs:Class ;
rdfs:label "resistance to triclabendazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to triclabendazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0032956 a rdfs:Class ;
rdfs:label "regulation of actin cytoskeleton organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ;
rdfs:subClassOf obo:GO_0032970 , obo:GO_0051493 , obo:GO_0065007 .
obo:PHIPO_0000893 a rdfs:Class ;
rdfs:label "sensitive to cefepime"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefepime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0003162 a rdfs:Class ;
rdfs:label "atrioventricular node development" ;
rdfs:comment "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system." ;
rdfs:subClassOf obo:GO_0048738 , obo:GO_0048856 .
obo:UBERON_0005598 a rdfs:Class ;
rdfs:label "trunk somite" ;
rdfs:comment "A somite that is part of a trunk." ;
rdfs:subClassOf obo:UBERON_0002329 .
obo:GO_0010936 a rdfs:Class ;
rdfs:label "negative regulation of macrophage cytokine production" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0002719 , obo:GO_0010935 , obo:GO_0065007 .
obo:GO_1905554 a rdfs:Class ;
rdfs:label "negative regulation of blood vessel branching" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching." ;
rdfs:subClassOf obo:GO_0016525 , obo:GO_0065007 , obo:GO_1905331 , obo:GO_1905553 .
obo:GO_0030225 a rdfs:Class ;
rdfs:label "macrophage differentiation" ;
rdfs:comment "The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage." ;
rdfs:subClassOf obo:GO_0002573 , obo:GO_0030154 , obo:GO_1903131 .
obo:UBERON_0005985 a rdfs:Class ;
rdfs:label "coronary vessel" ;
rdfs:comment "Any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation." ;
rdfs:subClassOf obo:UBERON_0000055 .
obo:PR_000011178 a rdfs:Class ;
rdfs:label "nuclear factor NF-kappa-B p100 subunit" ;
rdfs:comment "A transcription factor NF-kappa-B subunit that is a translation product of the human NFKB2 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001753 .
obo:UBERON_0011865 a rdfs:Class ;
rdfs:label "corneal stroma collagen fibril" ;
rdfs:comment "The connective tissue bundles in the extracellular matrix of corneal stroma that are composed of collagen, and play a role in tissue strength and elasticity." ;
rdfs:subClassOf obo:UBERON_0011860 .
obo:PHIPO_0000061 a rdfs:Class ;
rdfs:label "asexual spores absent"@en ;
rdfs:comment "A reproductive phenotype where asexual spores are absent (FAO:0000023)." ;
rdfs:subClassOf obo:PHIPO_0000082 .
obo:GO_0097511 a rdfs:Class ;
rdfs:label "dendritic cell dendrite" ;
rdfs:comment "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." ;
rdfs:subClassOf obo:GO_0120025 .
obo:GO_0007600 a rdfs:Class ;
rdfs:label "sensory perception" ;
rdfs:comment "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." ;
rdfs:subClassOf obo:GO_0050877 .
obo:PHIPO_0000717 a rdfs:Class ;
rdfs:label "sensitive to minocycline"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to minocycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0006056 a rdfs:Class ;
rdfs:label "posterior surface of head" ;
rdfs:subClassOf obo:UBERON_0036215 .
obo:UBERON_0011159 a rdfs:Class ;
rdfs:label "primary subdivision of cranial skeletal system" ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:GO_0010770 a rdfs:Class ;
rdfs:label "positive regulation of cell morphogenesis" ;
rdfs:comment "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0022604 , obo:GO_0065007 .
obo:CHEBI_22695 a rdfs:Class ;
rdfs:label "base" ;
rdfs:comment "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:GO_1901550 a rdfs:Class ;
rdfs:label "regulation of endothelial cell development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endothelial cell development." ;
rdfs:subClassOf obo:GO_0045601 , obo:GO_0060284 , obo:GO_0065007 .
obo:GO_1905139 a rdfs:Class ;
rdfs:label "apical ectodermal ridge formation" ;
rdfs:comment "The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0010659 a rdfs:Class ;
rdfs:label "cardiac muscle cell apoptotic process" ;
rdfs:comment "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0010658 .
obo:GO_0099175 a rdfs:Class ;
rdfs:label "regulation of postsynapse organization" ;
rdfs:comment "Any process that modulates the physical form of a postsynapse." ;
rdfs:subClassOf obo:GO_0050807 , obo:GO_0065007 .
obo:GO_0045992 a rdfs:Class ;
rdfs:label "negative regulation of embryonic development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." ;
rdfs:subClassOf obo:GO_0045995 , obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 .
obo:GO_1905771 a rdfs:Class ;
rdfs:label "negative regulation of mesodermal cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0065007 , obo:GO_1905770 .
obo:GO_0098773 a rdfs:Class ;
rdfs:label "skin epidermis development" ;
rdfs:comment "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0008544 , obo:GO_0048856 , obo:GO_0060429 .
obo:UBERON_0005691 a rdfs:Class ;
rdfs:label "4th arch mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a pharyngeal arch 4." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0009494 .
obo:GO_0005840 a rdfs:Class ;
rdfs:label "ribosome" ;
rdfs:comment "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins." ;
rdfs:subClassOf obo:GO_0043232 .
obo:UBERON_0009955 a rdfs:Class ;
rdfs:label "neurogenic placode" ;
rdfs:comment "Cranial ectodermal placode with potential to develop into a component of the nervous system, such as nerves or ganglia." ;
rdfs:subClassOf obo:UBERON_0002546 , obo:UBERON_0005085 .
obo:PHIPO_0001205 a rdfs:Class ;
rdfs:label "abnormal filament morphology"@en ;
rdfs:comment "A single species phenotype where the morphology of a cell is abnormal." ;
rdfs:subClassOf obo:PHIPO_0001221 .
obo:GO_0075015 a rdfs:Class ;
rdfs:label "formation of infection structure" ;
rdfs:comment "The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0005622 a rdfs:Class ;
rdfs:label "intracellular anatomical structure" ;
rdfs:comment "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_58951 a rdfs:Class ;
rdfs:label "short-chain fatty acid anion" ;
rdfs:comment "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6)." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:PHIPO_0001324 a rdfs:Class ;
rdfs:label "normal growth on pyrimethanil"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrimethanil (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_28545 a rdfs:Class ;
rdfs:label "valinomycin" ;
rdfs:comment "A twelve-membered cyclodepsipeptide composed of three repeating D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl units joined in sequence. An antibiotic found in several Streptomyces strains." ;
rdfs:subClassOf obo:CHEBI_35213 , obo:CHEBI_51026 .
obo:GO_0043523 a rdfs:Class ;
rdfs:label "regulation of neuron apoptotic process" ;
rdfs:comment "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:GO_0061581 a rdfs:Class ;
rdfs:label "corneal epithelial cell migration" ;
rdfs:comment "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism." ;
rdfs:subClassOf obo:GO_0010631 , obo:GO_0016477 .
obo:PHIPO_0000843 a rdfs:Class ;
rdfs:label "sensitive to bacitracin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to bacitracin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0090257 a rdfs:Class ;
rdfs:label "regulation of muscle system process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." ;
rdfs:subClassOf obo:GO_0044057 , obo:GO_0065007 .
obo:GO_0140650 a rdfs:Class ;
rdfs:label "radial glia-guided pyramidal neuron migration" ;
rdfs:comment "The radial migration of a pyramidal neuron along radial glial cells." ;
rdfs:subClassOf obo:GO_0001764 , obo:GO_0016477 .
obo:GO_1903076 a rdfs:Class ;
rdfs:label "regulation of protein localization to plasma membrane" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to plasma membrane." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904375 , obo:GO_1905475 .
obo:GO_1990904 a rdfs:Class ;
rdfs:label "ribonucleoprotein complex" ;
rdfs:comment "A macromolecular complex that contains both RNA and protein molecules." ;
rdfs:subClassOf obo:GO_0032991 .
obo:UBERON_0005251 a rdfs:Class ;
rdfs:label "yolk sac cavity" ;
rdfs:comment "An anatomical cavity that is part of a yolk sac [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002553 , obo:UBERON_0007473 , obo:UBERON_0012466 .
obo:GO_0043038 a rdfs:Class ;
rdfs:label "amino acid activation" ;
rdfs:comment "The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule." ;
rdfs:subClassOf obo:GO_0006520 .
a rdfs:Class ;
rdfs:label "fiber tracts" ;
rdfs:subClassOf , obo:UBERON_0000122 , obo:UBERON_0011215 .
a rdfs:Class ;
rdfs:label "Pallidum" ;
rdfs:subClassOf , obo:UBERON_0006514 , obo:UBERON_0011300 .
obo:CHEBI_57869 a rdfs:Class ;
rdfs:label "6-aminopenicillanic acid zwitterion" ;
rdfs:comment "Zwitterionic form of 6-aminopenicillanic acid arising from migration of a proton from the carboxy group to the 6-amino group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:GO_1903565 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to cilium" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903564 , obo:GO_1903828 .
obo:UBERON_0014891 a rdfs:Class ;
rdfs:label "brainstem white matter" ;
rdfs:comment "White matter that is part of a brainstem [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0003544 .
obo:PHIPO_0001309 a rdfs:Class ;
rdfs:label "normal growth on benomyl"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to benomyl (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0032331 a rdfs:Class ;
rdfs:label "negative regulation of chondrocyte differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation." ;
rdfs:subClassOf obo:GO_0032330 , obo:GO_0045596 , obo:GO_0061037 , obo:GO_0065007 .
obo:UBERON_0000102 a rdfs:Class ;
rdfs:label "lung vasculature" ;
rdfs:comment "The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]." ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0002201 , obo:UBERON_0006876 .
obo:PHIPO_0000709 a rdfs:Class ;
rdfs:label "resistance to clofazimine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to clofazimine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1900181 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to nucleus" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900180 , obo:GO_1903828 .
obo:GO_0098643 a rdfs:Class ;
rdfs:label "fibrillar collagen complex" ;
rdfs:comment "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." ;
rdfs:subClassOf obo:GO_0098644 .
obo:UBERON_0011927 a rdfs:Class ;
rdfs:label "preganglionic sympathetic fiber" ;
rdfs:comment "A cholinergic axonal fiber projecting from the CNS to a sympathetic ganglion." ;
rdfs:subClassOf obo:UBERON_0006134 , obo:UBERON_0011925 .
obo:GO_0014040 a rdfs:Class ;
rdfs:label "positive regulation of Schwann cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation." ;
rdfs:subClassOf obo:GO_0014038 , obo:GO_0045687 , obo:GO_0065007 .
obo:PHIPO_0000013 a rdfs:Class ;
rdfs:label "obsolete abnormal virulence" ;
rdfs:comment "A phenotype where virulence is abnormal (i.e. different than wild-type)." .
obo:GO_0045687 a rdfs:Class ;
rdfs:label "positive regulation of glial cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of glia cell differentiation." ;
rdfs:subClassOf obo:GO_0014015 , obo:GO_0045685 , obo:GO_0065007 .
obo:GO_0043524 a rdfs:Class ;
rdfs:label "negative regulation of neuron apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0043523 , obo:GO_0065007 .
obo:UBERON_0034717 a rdfs:Class ;
rdfs:label "integumental taste bud" ;
rdfs:comment "A taste bud that is located external to the digestive tube, on the head or body, as found in species such as goldfish." ;
rdfs:subClassOf obo:UBERON_0001727 .
obo:GO_0046831 a rdfs:Class ;
rdfs:label "regulation of RNA export from nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm." ;
rdfs:subClassOf obo:GO_0032239 , obo:GO_0046822 , obo:GO_0065007 .
obo:CHEBI_53000 a rdfs:Class ;
rdfs:label "epitope" ;
rdfs:comment "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:UBERON_0014705 a rdfs:Class ;
rdfs:label "median lingual swelling epithelium" ;
rdfs:comment "An epithelium that is part of a median lingual swelling." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0000490 , obo:UBERON_0003929 , obo:UBERON_0005291 , obo:UBERON_0005911 .
obo:PHIPO_0000492 a rdfs:Class ;
rdfs:label "metabolic process phenotype"@en ;
rdfs:comment "A single organism phenotype that affects the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." ;
rdfs:subClassOf obo:PHIPO_0000034 .
obo:CHEBI_26775 a rdfs:Class ;
rdfs:label "stilbene" ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_78840 .
obo:UBERON_0010371 a rdfs:Class ;
rdfs:label "ecto-epithelium" ;
rdfs:comment "Epithelium composed of cells that develops from the ectoderm[FMA,modified]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004121 .
obo:NCBITaxon_186623 a rdfs:Class ;
rdfs:label "Actinopteri" ;
rdfs:subClassOf obo:NCBITaxon_7898 .
obo:CL_0000393 a rdfs:Class ;
rdfs:label "electrically responsive cell" ;
rdfs:comment "A cell whose function is determined by its response to an electric signal." ;
rdfs:subClassOf obo:CL_0000211 .
obo:PHIPO_0001245 a rdfs:Class ;
rdfs:label "increased protein phosphorylation involved in host PAMP-triggered immunity (MAPK) signaling activated by pathogen"@en ;
rdfs:comment "A host immune system signaling pathway pathogen-host interaction phenotype observed during the activation of host PAMP-triggered immunity in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal." ;
rdfs:subClassOf obo:PHIPO_0001140 , obo:PHIPO_0001247 .
obo:UBERON_0001976 a rdfs:Class ;
rdfs:label "epithelium of esophagus" ;
rdfs:comment "The epithelial layer that lines the luminal space of the esophagus." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003350 , obo:UBERON_0003929 .
obo:GO_1903941 a rdfs:Class ;
rdfs:label "negative regulation of respiratory gaseous exchange" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange." ;
rdfs:subClassOf obo:GO_0043576 , obo:GO_0051241 , obo:GO_0065007 .
obo:UBERON_0003296 a rdfs:Class ;
rdfs:label "gland of diencephalon" ;
rdfs:comment "Any gland that is part of the diencephalon. Examples: pineal gland, neurohypophysis." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:GO_0022600 a rdfs:Class ;
rdfs:label "digestive system process" ;
rdfs:comment "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0003008 .
obo:CL_1000444 a rdfs:Class ;
rdfs:label "mesothelial cell of anterior chamber of eye" ;
rdfs:comment "A mesothelial cell that is part of the anterior chamber of eyeball." ;
rdfs:subClassOf obo:CL_0000077 .
obo:UBERON_0002368 a rdfs:Class ;
rdfs:label "endocrine gland" ;
rdfs:comment "Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:GO_0021987 a rdfs:Class ;
rdfs:label "cerebral cortex development" ;
rdfs:comment "The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0004896 a rdfs:Class ;
rdfs:label "cytokine receptor activity" ;
rdfs:comment "Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0004888 , obo:GO_0140375 .
obo:NCBITaxon_117570 a rdfs:Class ;
rdfs:label "Teleostomi" ;
rdfs:subClassOf obo:NCBITaxon_7776 .
obo:GO_0097530 a rdfs:Class ;
rdfs:label "granulocyte migration" ;
rdfs:comment "The movement of a granulocyte within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0097529 .
obo:CL_4307067 a rdfs:Class ;
rdfs:label "alpha2-tanycyte (Mmus)" ;
rdfs:comment "A alpha2-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdzph1 (Mmus), Wdr63 (Mmus), Dscaml1 (Mmus), P3h2 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Dscaml1, P3h2. These cells are located in the Hypothalamus , in or close to the regions: Periventricular hypothalamic nucleus, posterior part, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5247 Tanycyte NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4042018 , obo:CL_4301603 .
obo:GO_1903568 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to ciliary membrane" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903565 , obo:GO_1903567 , obo:GO_1904376 , obo:GO_1905476 .
obo:CL_1000303 a rdfs:Class ;
rdfs:label "fibroblast of areolar connective tissue" ;
rdfs:comment "A fibroblast that is part of the areolar connective tissue." ;
rdfs:subClassOf obo:CL_0000057 .
obo:GO_0032432 a rdfs:Class ;
rdfs:label "actin filament bundle" ;
rdfs:comment "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_36059 a rdfs:Class ;
rdfs:label "hydroxy monocarboxylic acid anion" ;
rdfs:comment "Any monocarboxylic acid anion carrying at least one hydroxy substituent." ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:GO_1901264 a rdfs:Class ;
rdfs:label "carbohydrate derivative transport" ;
rdfs:comment "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 .
obo:UBERON_0002199 a rdfs:Class ;
rdfs:label "integument" ;
rdfs:comment "The dermis, epidermis and hypodermis." ;
rdfs:subClassOf obo:UBERON_0010314 , obo:UBERON_0011216 .
obo:GO_0033239 a rdfs:Class ;
rdfs:label "negative regulation of amine metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0033238 , obo:GO_0065007 .
obo:GO_0010020 a rdfs:Class ;
rdfs:label "chloroplast fission" ;
rdfs:comment "The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis." ;
rdfs:subClassOf obo:GO_0009658 , obo:GO_0043572 , obo:GO_0048285 .
obo:UBERON_0010891 a rdfs:Class ;
rdfs:label "pectoral complex muscle" ;
rdfs:comment "A muscle of a pectoral girdle, pectoral fin or anterior limb." ;
rdfs:subClassOf obo:UBERON_0014892 .
obo:CHEBI_63367 a rdfs:Class ;
rdfs:label "monosaccharide derivative" ;
rdfs:comment "A carbohydrate derivative that is formally obtained from a monosaccharide." ;
rdfs:subClassOf obo:CHEBI_63299 .
obo:CHEBI_22506 a rdfs:Class ;
rdfs:label "aminoglycan" ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_65212 .
obo:GO_0160038 a rdfs:Class ;
rdfs:label "somatic sensory system development" ;
rdfs:comment "The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048880 .
obo:PHIPO_0001420 a rdfs:Class ;
rdfs:label "resistance to flutolanil" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to flutolanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_0002539 a rdfs:Class ;
rdfs:label "aortic smooth muscle cell" ;
rdfs:comment "A smooth muscle cell of the aorta." ;
rdfs:subClassOf obo:CL_0000359 , obo:CL_0019018 .
obo:CL_4300359 a rdfs:Class ;
rdfs:label "astrocyte of cerebrum (Mmus)" ;
rdfs:comment "A transcritpomically defined type of astrocytes primarily restricted to the dorsal regions of the cerebrum. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Lhx2 (Mmus), Gpc5 (Mmus), Nr2f1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:319 Astro-TE NN." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000127 .
obo:GO_0061307 a rdfs:Class ;
rdfs:label "cardiac neural crest cell differentiation involved in heart development" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches." ;
rdfs:subClassOf obo:GO_0014033 , obo:GO_0035051 .
obo:CHEBI_76969 a rdfs:Class ;
rdfs:label "bacterial metabolite" ;
rdfs:comment "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." ;
rdfs:subClassOf obo:CHEBI_75787 .
obo:CHEBI_38387 a rdfs:Class ;
rdfs:label "9,11,15-octadecatrienoic acid" ;
rdfs:comment "Any octadecatrienoic acid with three double bonds at positions 9, 11 and 15." ;
rdfs:subClassOf obo:CHEBI_25633 .
obo:CHEBI_38700 a rdfs:Class ;
rdfs:label "organic sodium salt" ;
rdfs:subClassOf obo:CHEBI_24868 , obo:CHEBI_26714 .
obo:GO_0045745 a rdfs:Class ;
rdfs:label "positive regulation of G protein-coupled receptor signaling pathway" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity." ;
rdfs:subClassOf obo:GO_0008277 , obo:GO_0009967 , obo:GO_0065007 .
obo:CHEBI_83399 a rdfs:Class ;
rdfs:label "marine xenobiotic metabolite" ;
rdfs:comment "Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms." ;
rdfs:subClassOf obo:CHEBI_76206 , obo:CHEBI_76507 .
obo:GO_1903552 a rdfs:Class ;
rdfs:label "negative regulation of extracellular exosome assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902116 , obo:GO_1903551 .
obo:GO_0051648 a rdfs:Class ;
rdfs:label "vesicle localization" ;
rdfs:comment "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051640 .
obo:GO_0007059 a rdfs:Class ;
rdfs:label "chromosome segregation" ;
rdfs:comment "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." ;
rdfs:subClassOf obo:GO_0022402 .
obo:GO_0003009 a rdfs:Class ;
rdfs:label "skeletal muscle contraction" ;
rdfs:comment "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control." ;
rdfs:subClassOf obo:GO_0006936 , obo:GO_0006941 .
obo:GO_0098852 a rdfs:Class ;
rdfs:label "lytic vacuole membrane" ;
rdfs:comment "The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell." ;
rdfs:subClassOf obo:GO_0005774 , obo:GO_0016020 .
obo:CHEBI_38976 a rdfs:Class ;
rdfs:label "alkylbenzene" ;
rdfs:comment "A monocyclic arene that is benzene substituted with one or more alkyl groups." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_33847 .
obo:UBERON_0002408 a rdfs:Class ;
rdfs:label "parietal serous pericardium" ;
rdfs:comment "Parietal serous membrane which is part of the pericardium and forms the outer layer of the pericardial sac." ;
rdfs:subClassOf obo:UBERON_0022351 .
obo:UBERON_0004087 a rdfs:Class ;
rdfs:label "vena cava" ;
rdfs:comment "Any of the veins that carries deoxygenated blood from a part of the body into the right atrium of the heart." ;
rdfs:subClassOf obo:UBERON_0003479 , obo:UBERON_0013768 .
obo:PHIPO_0001293 a rdfs:Class ;
rdfs:label "normal growth on fenpicoxamid"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to fenpicoxamid (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:UBERON_0010312 a rdfs:Class ;
rdfs:label "immature eye" ;
rdfs:comment "Developing anatomical structure that develops into the eyeball and associated structures." ;
rdfs:subClassOf obo:UBERON_0005423 .
obo:GO_0060285 a rdfs:Class ;
rdfs:label "cilium-dependent cell motility" ;
rdfs:comment "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." ;
rdfs:subClassOf obo:GO_0001539 .
obo:CHEBI_48336 a rdfs:Class ;
rdfs:label "(2R,4S)-ketoconazole" ;
rdfs:comment "A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2R,4S)-configuration." ;
rdfs:subClassOf obo:CHEBI_86411 .
obo:GO_1901610 a rdfs:Class ;
rdfs:label "positive regulation of vesicle transport along microtubule" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0065007 , obo:GO_1901608 .
obo:GO_0045823 a rdfs:Class ;
rdfs:label "positive regulation of heart contraction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of heart contraction." ;
rdfs:subClassOf obo:GO_0008016 , obo:GO_0065007 , obo:GO_1903524 .
obo:UBERON_0011582 a rdfs:Class ;
rdfs:label "paired limb/fin skeleton" ;
rdfs:comment "The collection of all skeletal elements in an individual limb or fin." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0010912 .
obo:CL_0011007 a rdfs:Class ;
rdfs:label "paraxial cell" ;
rdfs:comment "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites." ;
rdfs:subClassOf obo:CL_0000222 .
obo:UBERON_0001919 a rdfs:Class ;
rdfs:label "endothelium of vein" ;
rdfs:comment "An endothelium that is part of a vein [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0004638 , obo:UBERON_0004701 .
obo:GO_0022613 a rdfs:Class ;
rdfs:label "ribonucleoprotein complex biogenesis" ;
rdfs:comment "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." ;
rdfs:subClassOf obo:GO_0044085 .
obo:PHIPO_0000184 a rdfs:Class ;
rdfs:label "obsolete pathogen adhesion to host phenotype" .
obo:CHEBI_50249 a rdfs:Class ;
rdfs:label "anticoagulant" ;
rdfs:comment "An agent that prevents blood clotting." ;
rdfs:subClassOf obo:CHEBI_50248 .
obo:PHIPO_0000051 a rdfs:Class ;
rdfs:label "increased number of asexual spores"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of asexual spores is increased." ;
rdfs:subClassOf obo:PHIPO_0000082 .
obo:CHEBI_65255 a rdfs:Class ;
rdfs:label "food preservative" ;
rdfs:comment "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." ;
rdfs:subClassOf obo:CHEBI_64047 .
obo:GO_0021710 a rdfs:Class ;
rdfs:label "cerebellar stellate cell differentiation" ;
rdfs:comment "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." ;
rdfs:subClassOf obo:GO_0021533 , obo:GO_0021953 , obo:GO_0030154 , obo:GO_0097154 .
obo:CL_0002369 a rdfs:Class ;
rdfs:label "fungal spore" ;
rdfs:comment "A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions." ;
rdfs:subClassOf obo:CL_0000521 .
obo:GO_0050953 a rdfs:Class ;
rdfs:label "sensory perception of light stimulus" ;
rdfs:comment "The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." ;
rdfs:subClassOf obo:GO_0007600 .
obo:CHEBI_3499 a rdfs:Class ;
rdfs:label "cefotetan" ;
rdfs:comment "A semi-synthetic second-generation cephamycin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl, methoxy and {[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino groups at the 3, 7α, and 7β positions, respectively, of the cephem skeleton. It is resistant to a wide range of β-lactamases and is active against a broad spectrum of aerobic and anaerobic Gram-positive and Gram-negative microorganisms." ;
rdfs:subClassOf obo:CHEBI_55429 , obo:CHEBI_60911 .
obo:UBERON_0002215 a rdfs:Class ;
rdfs:label "synchondrosis" ;
rdfs:comment "Cartilaginous joint in which the articulating bones or cartilages are connected by hyaline cartilage. Examples: spheno-occipital synchondrosis, first sternocostal joint.[FMA]." ;
rdfs:subClassOf obo:UBERON_0002209 , obo:UBERON_0002213 .
obo:GO_0070444 a rdfs:Class ;
rdfs:label "oligodendrocyte progenitor proliferation" ;
rdfs:comment "The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0061351 .
obo:GO_0061190 a rdfs:Class ;
rdfs:label "regulation of sclerotome development" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0002793 a rdfs:Class ;
rdfs:label "positive regulation of peptide secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of peptide secretion." ;
rdfs:subClassOf obo:GO_0002791 , obo:GO_0051047 , obo:GO_0065007 .
obo:PHIPO_0000624 a rdfs:Class ;
rdfs:label "resistance to azithromycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to azithromycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_26710 a rdfs:Class ;
rdfs:label "sodium chloride" ;
rdfs:comment "An inorganic chloride salt having sodium(1+) as the counterion." ;
rdfs:subClassOf obo:CHEBI_36093 , obo:CHEBI_38702 , obo:CHEBI_50860 .
obo:PHIPO_0000932 a rdfs:Class ;
rdfs:label "normal cellular process"@en ;
rdfs:comment "A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000930 .
obo:PR_000001175 a rdfs:Class ;
rdfs:label "D(1A) dopamine receptor" ;
rdfs:comment "A D(1)-like dopamine receptor that is a translation product of the human DRD1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001107 .
obo:CHEBI_50635 a rdfs:Class ;
rdfs:label "EC 3.5.1.5 (urease) inhibitor" ;
rdfs:comment "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of urease (EC 3.5.1.5), reducing hydrolysis." ;
rdfs:subClassOf obo:CHEBI_76807 .
obo:CHEBI_39270 a rdfs:Class ;
rdfs:label "naphthofuran" ;
rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38104 .
obo:PHIPO_0000703 a rdfs:Class ;
rdfs:label "resistance to aureobasidin A"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to aureobasidin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000062 a rdfs:Class ;
rdfs:label "sexual spores absent"@en ;
rdfs:comment "A reproductive phenotype where sexual spores are absent (FAO:0000017)." ;
rdfs:subClassOf obo:PHIPO_0000077 .
obo:PHIPO_0000799 a rdfs:Class ;
rdfs:label "sensitive to ciprofloxacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ciprofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_24613 a rdfs:Class ;
rdfs:label "homodetic cyclic peptide" ;
rdfs:comment "A homodetic cyclic peptide is a cyclic peptide in which the ring consists solely of amino-acid residues in peptide linkages." ;
rdfs:subClassOf obo:CHEBI_23449 .
obo:UBERON_0009572 a rdfs:Class ;
rdfs:label "lumen of central canal of spinal cord" ;
rdfs:comment "A cerebrospinal fluid-filled space that runs longitudinally through the length of the entire spinal cord. The central canal is contiguous with the ventricular system of the brain. The central canal represents the adult remainder of the neural tube." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_1902511 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic DNA fragmentation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902510 , obo:GO_1903625 .
obo:UBERON_0004473 a rdfs:Class ;
rdfs:label "musculature of face" ;
rdfs:comment "Any collection of muscles that is part of a face." ;
rdfs:subClassOf obo:UBERON_0001015 , obo:UBERON_0008229 .
obo:GO_0071670 a rdfs:Class ;
rdfs:label "smooth muscle cell chemotaxis" ;
rdfs:comment "The directed movement of a smooth muscle cell in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0014909 , obo:GO_0060326 .
obo:UBERON_0006241 a rdfs:Class ;
rdfs:label "future spinal cord" ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:CHEBI_59064 a rdfs:Class ;
rdfs:label "colistin A" ;
rdfs:subClassOf obo:CHEBI_25903 , obo:CHEBI_59062 .
obo:GO_1900147 a rdfs:Class ;
rdfs:label "regulation of Schwann cell migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of Schwann cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903975 .
obo:UBERON_0001021 a rdfs:Class ;
rdfs:label "nerve" ;
rdfs:comment "An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures." ;
rdfs:subClassOf obo:UBERON_0000122 .
obo:GO_0000962 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial RNA catabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ;
rdfs:subClassOf obo:GO_0000960 , obo:GO_0009896 , obo:GO_0051254 , obo:GO_0065007 .
obo:UBERON_0034903 a rdfs:Class ;
rdfs:label "left atrium endocardium" ;
rdfs:comment "Endocardium that is part of the left atrium." ;
rdfs:subClassOf obo:UBERON_0002165 , obo:UBERON_0002166 .
obo:UBERON_0009536 a rdfs:Class ;
rdfs:label "vascular element of left lung" ;
rdfs:comment "A vascular plexus that is part of a left lung." ;
rdfs:subClassOf obo:UBERON_0000102 , obo:UBERON_0005629 .
obo:UBERON_0000485 a rdfs:Class ;
rdfs:label "simple columnar epithelium" ;
rdfs:comment "Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0012274 .
obo:PHIPO_0001323 a rdfs:Class ;
rdfs:label "sensitive to flumorph"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to flumorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0003120 a rdfs:Class ;
rdfs:label "pharyngeal arch artery 3" ;
rdfs:comment "The vessels formed within the third pair of branchial arches in embryogenesis." ;
rdfs:subClassOf obo:UBERON_0004363 .
obo:UBERON_0022248 a rdfs:Class ;
rdfs:label "cerebral nerve fasciculus" ;
rdfs:subClassOf obo:UBERON_0001019 , obo:UBERON_0005838 .
obo:CHEBI_36563 a rdfs:Class ;
rdfs:label "zinc group coordination entity" ;
rdfs:subClassOf obo:CHEBI_33240 , obo:CHEBI_33673 .
obo:UBERON_0014531 a rdfs:Class ;
rdfs:label "white matter lamina of diencephalon" ;
rdfs:subClassOf obo:UBERON_0014530 .
obo:PHIPO_0000675 a rdfs:Class ;
rdfs:label "resistance to itraconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to itraconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0060434 a rdfs:Class ;
rdfs:label "bronchus morphogenesis" ;
rdfs:comment "The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 , obo:GO_0035239 .
obo:CL_4307100 a rdfs:Class ;
rdfs:label "NFOL NN_2 Rgs16 newly formed oligodendrocyte (Mmus)" ;
rdfs:comment "A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Rgs16 (Mmus), Rhbdl2 (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Rgs16, Rhbdl2. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5280 NFOL NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301612 .
obo:GO_0014805 a rdfs:Class ;
rdfs:label "smooth muscle adaptation" ;
rdfs:comment "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." ;
rdfs:subClassOf obo:GO_0043500 .
obo:GO_0007049 a rdfs:Class ;
rdfs:label "cell cycle" ;
rdfs:comment "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." ;
rdfs:subClassOf obo:GO_0009987 .
obo:UBERON_0002019 a rdfs:Class ;
rdfs:label "accessory XI nerve" ;
rdfs:comment "A cranial nerve that originates from neurons in the medulla and in the cervical spinal cord." ;
rdfs:subClassOf obo:UBERON_0001021 , obo:UBERON_0035642 .
obo:PHIPO_0000070 a rdfs:Class ;
rdfs:label "altered in pigment accumulation in sexual spore"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of coloring matter in a sexual spore cell is altered." ;
rdfs:subClassOf obo:PHIPO_0000285 .
obo:UBERON_0000045 a rdfs:Class ;
rdfs:label "ganglion" ;
rdfs:comment "A biological tissue mass, most commonly a mass of nerve cell bodies." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:CL_0007009 a rdfs:Class ;
rdfs:label "prechondroblast" ;
rdfs:comment "Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells." ;
rdfs:subClassOf obo:CL_0011026 .
obo:CHEBI_23765 a rdfs:Class ;
rdfs:label "quinolone" ;
rdfs:subClassOf obo:CHEBI_26513 .
obo:GO_0099014 a rdfs:Class ;
rdfs:label "neuronal dense core vesicle organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0061109 .
obo:CL_0002352 a rdfs:Class ;
rdfs:label "gestational hematopoietic stem cell" ;
rdfs:comment "A hematopoietic stem cell that exists during embryogenesis." ;
rdfs:subClassOf obo:CL_0000037 .
obo:GO_0044703 a rdfs:Class ;
rdfs:label "multi-organism reproductive process" ;
rdfs:comment "A biological process that directly contributes to the process of producing new individuals, involving another organism." ;
rdfs:subClassOf obo:GO_0022414 .
obo:UBERON_0007473 a rdfs:Class ;
rdfs:label "lumen of epithelial sac" ;
rdfs:comment "The space within an epithelial sphere." ;
rdfs:subClassOf obo:UBERON_0000464 , obo:UBERON_0012467 .
obo:PHIPO_0000111 a rdfs:Class ;
rdfs:label "delayed pathogen penetration across the barrier"@en ;
rdfs:comment "A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration begins later than normal when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000024 .
obo:GO_1903905 a rdfs:Class ;
rdfs:label "positive regulation of establishment of T cell polarity" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity." ;
rdfs:subClassOf obo:GO_0050870 , obo:GO_0065007 , obo:GO_1903903 .
obo:UBERON_0003915 a rdfs:Class ;
rdfs:label "endothelial tube" ;
rdfs:comment "Any endothelium that has the quality of being cylindrical [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0003914 .
obo:CHEBI_36829 a rdfs:Class ;
rdfs:label "polyatomic monoanion" ;
rdfs:subClassOf obo:CHEBI_33273 , obo:CHEBI_36830 .
obo:PHIPO_0001231 a rdfs:Class ;
rdfs:label "host defense-induced RNA present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the host RNA usually present during infection is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001263 .
obo:PATO_0000587 a rdfs:Class ;
rdfs:label "decreased size" ;
rdfs:comment "A size quality which is relatively low." ;
rdfs:subClassOf obo:PATO_0000117 , obo:PATO_0002303 .
obo:CHEBI_73080 a rdfs:Class ;
rdfs:label "hemiaminal" ;
rdfs:comment "Any organic amino compound that has an amino group and a hydroxy group attached to the same carbon atom. Hemiaminals are intermediates in the formation of imines by addition of an amine to an aldehyde or ketone; those derived from primary amines are particularly unstable." ;
rdfs:subClassOf obo:CHEBI_33822 , obo:CHEBI_50047 .
obo:PHIPO_0000147 a rdfs:Class ;
rdfs:label "abolished DNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000145 .
obo:GO_0170044 a rdfs:Class ;
rdfs:label "non-proteinogenic amino acid catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of non-proteinogenic amino acids." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0046395 , obo:GO_0170041 .
obo:UBERON_0015212 a rdfs:Class ;
rdfs:label "lateral structure" ;
rdfs:comment "Any structure that is placed on one side of the left-right axis of a bilaterian." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0003163 a rdfs:Class ;
rdfs:label "sinoatrial node development" ;
rdfs:comment "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node." ;
rdfs:subClassOf obo:GO_0003228 , obo:GO_0048856 .
obo:GO_0034352 a rdfs:Class ;
rdfs:label "positive regulation of glial cell apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process." ;
rdfs:subClassOf obo:GO_0034350 , obo:GO_0043065 , obo:GO_0065007 .
obo:PHIPO_0001271 a rdfs:Class ;
rdfs:label "presence of pathogen sexual spores within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host in which the frequency of occurrence of sexual spores is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000443 .
obo:GO_0006950 a rdfs:Class ;
rdfs:label "response to stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0050896 .
obo:PHIPO_0000378 a rdfs:Class ;
rdfs:label "sensitive to carboxin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to carboxin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0011863 a rdfs:Class ;
rdfs:label "bone collagen fibril" ;
rdfs:comment "The connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity." ;
rdfs:subClassOf obo:UBERON_0011860 .
obo:PR_000016004 a rdfs:Class ;
rdfs:label "tachykinin-3" ;
rdfs:comment "A protein that is a translation product of the human TAC3 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_45367 a rdfs:Class ;
rdfs:label "rifabutin" ;
rdfs:subClassOf obo:CHEBI_26580 .
obo:UBERON_0014776 a rdfs:Class ;
rdfs:label "midbrain neuromere" ;
rdfs:comment "A neuromere that is part of the presumptive midbrain." ;
rdfs:subClassOf obo:UBERON_0004731 .
obo:GO_0003219 a rdfs:Class ;
rdfs:label "cardiac right ventricle formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts." ;
rdfs:subClassOf obo:GO_0003211 , obo:GO_0048646 .
obo:CL_4307114 a rdfs:Class ;
rdfs:label "ABC NN_1 Dapl1 arachnoid barrier cell (Mmus)" ;
rdfs:comment "A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc47a1 (Mmus), Dapl1 (Mmus). It is distinguished from other ABC NN cells by expression of Dapl1. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5294 ABC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301616 .
obo:CL_0000153 a rdfs:Class ;
rdfs:label "glycosaminoglycan secreting cell" ;
rdfs:comment "A cell that secretes glycosaminoglycans." ;
rdfs:subClassOf obo:CL_0000327 , obo:CL_0000447 .
obo:PHIPO_0001188 a rdfs:Class ;
rdfs:label "obsolete gene-for-gene interaction phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the outcome of a gene-for-gene relationship in plant pathogen interactions. The gene-for-gene hypothesis follows that for each gene controlling resistance (R) in the host there is a corresponding gene controlling avirulence (avr) in the pathogen." .
obo:CHEBI_64290 a rdfs:Class ;
rdfs:label "erythromycin cation" ;
rdfs:comment "An organic cation obtained by protonation of any erythromycin." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:GO_0099172 a rdfs:Class ;
rdfs:label "presynapse organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0016043 .
obo:GO_0098645 a rdfs:Class ;
rdfs:label "complex of network-forming collagens" ;
rdfs:comment "A supramolecular complex that consists of collagen triple helices associated to form a network." ;
rdfs:subClassOf obo:GO_0098644 .
obo:CL_0002454 a rdfs:Class ;
rdfs:label "CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell" ;
rdfs:comment "CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8-alpha-negative and is CD205-positive." ;
rdfs:subClassOf obo:CL_0002465 .
obo:GO_0003348 a rdfs:Class ;
rdfs:label "cardiac endothelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0035051 , obo:GO_0045446 .
obo:CL_2000022 a rdfs:Class ;
rdfs:label "cardiac septum cell" ;
rdfs:comment "Any native cell that is part of a cardiac septum." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0002494 .
obo:UBERON_0002318 a rdfs:Class ;
rdfs:label "white matter of spinal cord" ;
rdfs:comment "The regions of the spinal cord that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites." ;
rdfs:subClassOf obo:UBERON_0002316 .
obo:PHIPO_0000351 a rdfs:Class ;
rdfs:label "obsolete pathogen is able to penetrate host" ;
rdfs:comment "A pathogen growth with host phenotype in which the pathogen is able to penetrate the host." .
obo:CHEBI_59905 a rdfs:Class .
obo:PR_000001408 a rdfs:Class ;
rdfs:label "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1" ;
rdfs:comment "An ADP-ribosyl cyclase that is a translation product of the human CD38 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001281 .
obo:GO_0030854 a rdfs:Class ;
rdfs:label "positive regulation of granulocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of granulocyte differentiation." ;
rdfs:subClassOf obo:GO_0002763 , obo:GO_0030852 , obo:GO_0065007 .
obo:PATO_0000467 a rdfs:Class ;
rdfs:label "present" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's existence." ;
rdfs:subClassOf obo:PATO_0000070 .
obo:GO_2000181 a rdfs:Class ;
rdfs:label "negative regulation of blood vessel morphogenesis" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0065007 , obo:GO_1901343 .
obo:GO_0043470 a rdfs:Class ;
rdfs:label "regulation of carbohydrate catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates." ;
rdfs:subClassOf obo:GO_0006109 , obo:GO_0009894 , obo:GO_0065007 .
obo:UBERON_0009471 a rdfs:Class ;
rdfs:label "dorsum of tongue" ;
rdfs:comment "The superior surface of the tongue divided by the sulcus terminalis into an anterior two-thirds, the presulcal part (pars presulcalis). and a posterior one-third, the postsulcal part (pars postsulcalis)." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:UBERON_0007271 a rdfs:Class ;
rdfs:label "appendage musculature" ;
rdfs:comment "Any collection of muscles that is part of an appendage." ;
rdfs:subClassOf obo:UBERON_0001015 .
obo:PATO_0045047 a rdfs:Class ;
rdfs:label "normal resistance to" ;
rdfs:comment "A resistance to a stimulus which is relatively normal or average" ;
rdfs:subClassOf obo:PATO_0001178 , obo:PATO_0045001 .
obo:CHEBI_24834 a rdfs:Class ;
rdfs:label "inorganic anion" ;
rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_36914 .
obo:GO_0033028 a rdfs:Class ;
rdfs:label "myeloid cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." ;
rdfs:subClassOf obo:GO_0006915 .
obo:CHEBI_45373 a rdfs:Class ;
rdfs:label "sulfanilamide" ;
rdfs:comment "A sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position." ;
rdfs:subClassOf obo:CHEBI_48975 , obo:CHEBI_87228 .
obo:CL_0000644 a rdfs:Class ;
rdfs:label "Bergmann glial cell" ;
rdfs:comment "Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses." ;
rdfs:subClassOf obo:CL_0002603 .
obo:CHEBI_7489 a rdfs:Class ;
rdfs:label "neamine" ;
rdfs:comment "2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-α-D-glucosaminyl group." ;
rdfs:subClassOf obo:CHEBI_47779 , obo:CHEBI_53628 .
obo:GO_0021545 a rdfs:Class ;
rdfs:label "cranial nerve development" ;
rdfs:comment "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." ;
rdfs:subClassOf obo:GO_0021675 , obo:GO_0048856 .
obo:IAO_0000102 a rdfs:Class ;
rdfs:label "data about an ontology part"@en ;
rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
rdfs:subClassOf obo:IAO_0000027 .
obo:CL_0002362 a rdfs:Class ;
rdfs:label "cerebellar granule cell precursor" ;
rdfs:comment "A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and HNK1-positive." ;
rdfs:subClassOf obo:CL_0000031 , obo:CL_0002319 .
obo:PATO_0001400 a rdfs:Class ;
rdfs:label "unipotent" ;
rdfs:comment "A cellular potency that is the capacity to produce only one differentiated cell type." ;
rdfs:subClassOf obo:PATO_0001397 .
obo:GO_0120229 a rdfs:Class ;
rdfs:label "protein localization to motile cilium" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a motile cilium." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0061512 .
obo:GO_0033043 a rdfs:Class ;
rdfs:label "regulation of organelle organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:CL_2000063 a rdfs:Class ;
rdfs:label "ovarian fibroblast" ;
rdfs:comment "Any fibroblast that is part of a female gonad." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0002132 .
obo:CHEBI_61689 a rdfs:Class ;
rdfs:label "amino cyclitol" ;
rdfs:comment "Any cyclitol having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups." ;
rdfs:subClassOf obo:CHEBI_23451 .
obo:GO_0055007 a rdfs:Class ;
rdfs:label "cardiac muscle cell differentiation" ;
rdfs:comment "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0035051 , obo:GO_0051146 .
obo:UBERON_0000092 a rdfs:Class ;
rdfs:label "post-embryonic stage" ;
rdfs:comment "Stage succeeding embryo, including mature structure." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:GO_0030050 a rdfs:Class ;
rdfs:label "vesicle transport along actin filament" ;
rdfs:comment "Movement of a vesicle along an actin filament, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0030048 , obo:GO_0046907 , obo:GO_0099515 , obo:GO_0099518 .
obo:GO_0050807 a rdfs:Class ;
rdfs:label "regulation of synapse organization" ;
rdfs:comment "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0045987 a rdfs:Class ;
rdfs:label "positive regulation of smooth muscle contraction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction." ;
rdfs:subClassOf obo:GO_0006940 , obo:GO_0045933 , obo:GO_0065007 .
obo:PHIPO_0000252 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction RNA localization" ;
rdfs:comment "A pathogen host interaction phenotype in which the localization of an RNA in a cell is abnormal. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." .
obo:UBERON_0003478 a rdfs:Class ;
rdfs:label "vein of lower lip" ;
rdfs:comment "The inferior labial vein is the vein receiving blood from the lower lip." ;
rdfs:subClassOf obo:UBERON_0001638 , obo:UBERON_0013136 .
obo:UBERON_0034721 a rdfs:Class ;
rdfs:label "pharyngeal taste bud" ;
rdfs:comment "A taste bud that is located in the pharynx." ;
rdfs:subClassOf obo:UBERON_0001727 , obo:UBERON_0013765 .
obo:CL_4310085 a rdfs:Class ;
rdfs:label "LAMP5-LHX6 GABA Lamp5 Lhx6 neuron (Primate)" ;
rdfs:comment "A Lamp5 Lhx6 neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:LAMP5-LHX6 GABA." ;
rdfs:subClassOf obo:CL_4042013 .
obo:GO_0050975 a rdfs:Class ;
rdfs:label "sensory perception of touch" ;
rdfs:comment "The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)." ;
rdfs:subClassOf obo:GO_0050954 .
obo:PHIPO_0001097 a rdfs:Class ;
rdfs:label "resistance to cell wall stress"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to a cell wall stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die)." ;
rdfs:subClassOf obo:PHIPO_0001096 .
obo:GO_0140103 a rdfs:Class ;
rdfs:label "catalytic activity, acting on a glycoprotein" ;
rdfs:comment "Catalysis of a biochemical reaction in which one of the substrates is a glycoprotein." ;
rdfs:subClassOf obo:GO_0003824 , obo:GO_0140096 .
obo:PR_000050216 a rdfs:Class ;
rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45R" ;
rdfs:comment "A receptor-type tyrosine-protein phosphatase C that is a translation product of a transcript that minimally includes the region encoded by the variable exon 4(A)." ;
rdfs:subClassOf obo:PR_000001006 .
obo:UBERON_0003389 a rdfs:Class ;
rdfs:label "mesothelium of diaphragm" ;
rdfs:comment "A mesothelium that is part of a diaphragm [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001136 , obo:UBERON_0004807 .
obo:GO_0001525 a rdfs:Class ;
rdfs:label "angiogenesis" ;
rdfs:comment "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels." ;
rdfs:subClassOf obo:GO_0048646 .
obo:UBERON_0006347 a rdfs:Class ;
rdfs:label "communicating artery" ;
rdfs:comment "An artery that connects two larger arteries." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:UBERON_0036656 a rdfs:Class ;
rdfs:label "wall of third ventricle" ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0036661 .
obo:UBERON_0003831 a rdfs:Class ;
rdfs:label "respiratory system muscle" ;
rdfs:comment "Any muscle organ that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001630 .
obo:PHIPO_0000686 a rdfs:Class ;
rdfs:label "resistance to caspofungin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to caspofungin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_17698 a rdfs:Class ;
rdfs:label "chloramphenicol" ;
rdfs:comment "An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions." ;
rdfs:subClassOf obo:CHEBI_23824 , obo:CHEBI_35716 , obo:CHEBI_36683 , obo:CHEBI_37622 .
obo:GO_0051078 a rdfs:Class ;
rdfs:label "meiotic nuclear membrane disassembly" ;
rdfs:comment "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs." ;
rdfs:subClassOf obo:GO_0051081 , obo:GO_1903046 .
obo:GO_0003203 a rdfs:Class ;
rdfs:label "endocardial cushion morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0072132 .
obo:CL_0000121 a rdfs:Class ;
rdfs:label "Purkinje cell" ;
rdfs:comment "An inhibitory neuron and the sole output neuron of the cerebellar cortex, the Purkinje cell's soma is located between the granular and molecular layers of the cerebellum. It is one of the largest neural cells in the mammalian brain, ranging from 50 to 80 micrometres in diameter. Purkinje cells have planar, fan-shaped dendrites that branch extensively with little overlap. This cell type receives synaptic input from parallel fibres, which modulate high-frequency spike activity known as \"simple spikes,\" and climbing fibres, which modulate infrequent calcium spike activity known as \"complex spikes\". Purkinje cells are involved in motor coordination, particularly in correcting movements in progress." ;
rdfs:subClassOf obo:CL_0000617 , obo:CL_1001611 .
obo:GO_0015464 a rdfs:Class ;
rdfs:label "acetylcholine receptor activity" ;
rdfs:comment "Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0004888 , obo:GO_0038023 , obo:GO_0098960 .
obo:PHIPO_0001318 a rdfs:Class ;
rdfs:label "normal growth on metalaxyl"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to metalaxyl (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PHIPO_0001044 a rdfs:Class ;
rdfs:label "obsolete protein absent in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of protein measured in a pathogen or host cell is too low to detect. Total protein or a specific protein may be affected." .
obo:CHEBI_35117 a rdfs:Class ;
rdfs:label "manganese coordination entity" ;
rdfs:subClassOf obo:CHEBI_25154 , obo:CHEBI_33861 .
obo:CHEBI_37142 a rdfs:Class ;
rdfs:label "organoiodine compound" ;
rdfs:comment "An organoiodine compound is a compound containing at least one carbon-iodine bond." ;
rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_24860 .
obo:GO_0099082 a rdfs:Class ;
rdfs:label "retrograde trans-synaptic signaling by neuropeptide" ;
rdfs:comment "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide." ;
rdfs:subClassOf obo:GO_0098917 , obo:GO_0099537 , obo:GO_0099540 .
obo:UBERON_0003891 a rdfs:Class ;
rdfs:label "stroma" ;
rdfs:comment "Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:GO_0021619 a rdfs:Class ;
rdfs:label "hypoglossal nerve maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." ;
rdfs:subClassOf obo:GO_0021605 , obo:GO_0021700 .
obo:CL_0000327 a rdfs:Class ;
rdfs:label "extracellular matrix secreting cell" ;
rdfs:subClassOf obo:CL_0000499 .
obo:PHIPO_0001459 a rdfs:Class ;
rdfs:label "unaffected susceptibility to pathogen"@en ;
rdfs:comment "A quality of an organism in which its proneness to infection, colonization, or disease following exposure to a pathogen is comparable to that of a reference or wild-type organism under equivalent conditions." ;
rdfs:subClassOf obo:PHIPO_0001456 .
obo:PATO_0001997 a rdfs:Class ;
rdfs:label "decreased amount" ;
rdfs:comment "An amount which is relatively low." ;
rdfs:subClassOf obo:PATO_0000070 , obo:PATO_0000467 , obo:PATO_0002301 .
obo:PHIPO_0000518 a rdfs:Class ;
rdfs:label "lipid droplets present in normal numbers"@en ;
rdfs:comment "A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain the same number of lipid droplets as normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000159 .
obo:CHEBI_35610 a rdfs:Class ;
rdfs:label "antineoplastic agent" ;
rdfs:comment "A substance that inhibits or prevents the proliferation of neoplasms." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:UBERON_0009652 a rdfs:Class ;
rdfs:label "bronchus basement membrane" ;
rdfs:comment "A basement membrane that is part of a bronchus." ;
rdfs:subClassOf obo:UBERON_0005769 , obo:UBERON_0015329 .
obo:CHEBI_90710 a rdfs:Class ;
rdfs:label "receptor modulator" ;
rdfs:comment "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0141188 a rdfs:Class ;
rdfs:label "nucleic acid catabolic process" ;
rdfs:comment "The cellular DNA metabolic process resulting in the breakdown of a nucleic acid." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0009057 , obo:GO_0034655 , obo:GO_0090304 .
obo:GO_1902512 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic DNA fragmentation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902510 , obo:GO_1903626 .
obo:GO_1903942 a rdfs:Class ;
rdfs:label "positive regulation of respiratory gaseous exchange" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange." ;
rdfs:subClassOf obo:GO_0043576 , obo:GO_0051240 , obo:GO_0065007 .
obo:UBERON_0001458 a rdfs:Class ;
rdfs:label "skin of lip" ;
rdfs:comment "A zone of skin that is part of a lip [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_1000021 .
obo:GO_0070828 a rdfs:Class ;
rdfs:label "heterochromatin organization" ;
rdfs:comment "Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin." ;
rdfs:subClassOf obo:GO_0006325 , obo:GO_0016043 .
obo:GO_0032939 a rdfs:Class ;
rdfs:label "positive regulation of translation in response to oxidative stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0032056 , obo:GO_0065007 .
obo:CHEBI_38295 a rdfs:Class ;
rdfs:label "azabicycloalkane" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 .
obo:GO_0002371 a rdfs:Class ;
rdfs:label "dendritic cell cytokine production" ;
rdfs:comment "Any process that contributes to cytokine production by a dendritic cell." ;
rdfs:subClassOf obo:GO_0001816 , obo:GO_0002367 , obo:GO_0002443 .
obo:GO_0001960 a rdfs:Class ;
rdfs:label "negative regulation of cytokine-mediated signaling pathway" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway." ;
rdfs:subClassOf obo:GO_0001959 , obo:GO_0009968 , obo:GO_0060761 , obo:GO_0065007 .
obo:GO_0032378 a rdfs:Class ;
rdfs:label "negative regulation of intracellular lipid transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells." ;
rdfs:subClassOf obo:GO_0032369 , obo:GO_0032377 , obo:GO_0032387 , obo:GO_0065007 .
obo:GO_0071709 a rdfs:Class ;
rdfs:label "membrane assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a membrane." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0061024 .
obo:GO_0003133 a rdfs:Class ;
rdfs:label "endodermal-mesodermal cell signaling" ;
rdfs:comment "Any process that mediates the transfer of information from endodermal cells to mesodermal cells." ;
rdfs:subClassOf obo:GO_0007267 .
obo:PR_P06332 a rdfs:Class ;
rdfs:label "T-cell surface glycoprotein CD4 (mouse)" ;
rdfs:comment "A CD4 molecule that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001004 , obo:PR_000029032 .
obo:UBERON_0006601 a rdfs:Class ;
rdfs:label "presumptive ectoderm" ;
rdfs:comment "Presumptive structure of the blastula that will develop into ectoderm." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:CHEBI_26708 a rdfs:Class ;
rdfs:label "sodium atom" ;
rdfs:subClassOf obo:CHEBI_22314 .
obo:PHIPO_0001397 a rdfs:Class ;
rdfs:label "sensitive to cell wall stress"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to a cell wall stress. Typically, individuals or populations are deemed sensitive to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die)." ;
rdfs:subClassOf obo:PHIPO_0001098 .
obo:GO_0022009 a rdfs:Class ;
rdfs:label "central nervous system vasculogenesis" ;
rdfs:comment "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier." ;
rdfs:subClassOf obo:GO_0001570 .
obo:CL_4310122 a rdfs:Class ;
rdfs:label "STR SST-ADARB2 GABA sst GABAergic interneuron (Primate)" ;
rdfs:comment "A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-ADARB2 GABA." ;
rdfs:subClassOf obo:CL_4023017 .
obo:CHEBI_29340 a rdfs:Class ;
rdfs:label "hydridonitrate(2-)" ;
rdfs:comment "A divalent inorganic anion resulting from the removal of two protons from ammonia." ;
rdfs:subClassOf obo:CHEBI_35106 , obo:CHEBI_79388 .
obo:GO_0002679 a rdfs:Class ;
rdfs:label "respiratory burst involved in defense response" ;
rdfs:comment "A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0002252 , obo:GO_0045730 .
obo:UBERON_0036303 a rdfs:Class ;
rdfs:label "vasculature of central nervous system" ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0036302 .
obo:UBERON_0009644 a rdfs:Class ;
rdfs:label "trachea non-cartilage connective tissue" ;
rdfs:subClassOf obo:UBERON_0003571 .
obo:CHEBI_57971 a rdfs:Class ;
rdfs:label "hygromycin B(3+)" ;
rdfs:comment "An ammonium ion that is the trication of hygromycin B arising from protonation of the three amino groups; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35274 .
obo:GO_0010613 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle hypertrophy" ;
rdfs:comment "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." ;
rdfs:subClassOf obo:GO_0010611 , obo:GO_0014742 , obo:GO_0065007 .
obo:CHEBI_23480 a rdfs:Class ;
rdfs:label "cyclohexanols" ;
rdfs:comment "An alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:PHIPO_0000441 a rdfs:Class ;
rdfs:label "abnormal pathogen reproductive phenotype within host"@en ;
rdfs:comment "A pathogen host interaction phenotype where the pathogen reproductive process within the host is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000439 .
obo:PHIPO_0000340 a rdfs:Class ;
rdfs:label "abolished pathogen cell to cell migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally within the host organism is abolished (pathogen migration was present within the host and is now absent)." ;
rdfs:subClassOf obo:PHIPO_0000334 .
obo:GO_0005577 a rdfs:Class ;
rdfs:label "fibrinogen complex" ;
rdfs:comment "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds." ;
rdfs:subClassOf obo:GO_0140392 .
obo:CHEBI_192486 a rdfs:Class ;
rdfs:label "ciprofloxacin(1+)" ;
rdfs:comment "A secondary ammonium ion that is the conjugate acid of ciprofloxacin resulting from the protonation of the NH group; major species at acidic pH." ;
rdfs:subClassOf obo:CHEBI_137419 .
obo:GO_0043931 a rdfs:Class ;
rdfs:label "ossification involved in bone maturation" ;
rdfs:comment "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state." ;
rdfs:subClassOf obo:GO_0001503 .
obo:CHEBI_36566 a rdfs:Class ;
rdfs:label "zinc coordination entity" ;
rdfs:subClassOf obo:CHEBI_27364 , obo:CHEBI_36563 .
obo:UBERON_0001082 a rdfs:Class ;
rdfs:label "epicardium of ventricle" ;
rdfs:comment "An epicardial layer that lines a cardiac ventricle." ;
rdfs:subClassOf obo:UBERON_0002348 .
obo:GO_0060631 a rdfs:Class ;
rdfs:label "regulation of meiosis I" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ;
rdfs:subClassOf obo:GO_0040020 , obo:GO_0065007 .
obo:PHIPO_0001148 a rdfs:Class ;
rdfs:label "unaltered reactive oxygen species production"@en ;
rdfs:comment "A single species metabolic cellular process phenotype in which the formation of reactive oxygen species (any molecules or ions formed by the incomplete one-electron reduction of oxygen) is unaltered.(GO:1903409)" ;
rdfs:subClassOf obo:PHIPO_0001147 .
obo:GO_0090493 a rdfs:Class ;
rdfs:label "catecholamine uptake" ;
rdfs:comment "The directed movement of catecholamine into a cell." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015850 , obo:GO_0071705 .
obo:CL_4052002 a rdfs:Class ;
rdfs:label "syncytial cell" ;
rdfs:comment "A multinucleate cell formed by the fusion of multiple uninuclear cells through plasma membrane fusion. This process leads to a single large cell containing multiple nuclei within a shared cytoplasm." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000228 .
obo:GO_0002036 a rdfs:Class ;
rdfs:label "regulation of L-glutamate import across plasma membrane" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of L-glutamate import into a cell." ;
rdfs:subClassOf obo:GO_0010958 , obo:GO_0032890 , obo:GO_0065007 .
obo:PHIPO_0000613 a rdfs:Class ;
rdfs:label "resistance to epoxyconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to epoxyconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0001723 a rdfs:Class ;
rdfs:label "tongue" ;
rdfs:comment "A muscular organ in the floor of the mouth." ;
rdfs:subClassOf obo:UBERON_0000020 , obo:UBERON_0013765 .
obo:GO_0048284 a rdfs:Class ;
rdfs:label "organelle fusion" ;
rdfs:comment "The creation of a single organelle from two or more organelles." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0009987 .
obo:CHEBI_46774 a rdfs:Class ;
rdfs:label "polyether" ;
rdfs:comment "Any ether that contains more than one ether linkage." ;
rdfs:subClassOf obo:CHEBI_25698 .
obo:GO_1905755 a rdfs:Class ;
rdfs:label "protein localization to cytoplasmic microtubule" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0035372 .
obo:GO_0051081 a rdfs:Class ;
rdfs:label "nuclear membrane disassembly" ;
rdfs:comment "The controlled breakdown of the nuclear membranes, for example during cellular division." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0030397 , obo:GO_0071763 .
obo:RO_0002577 a rdfs:Class ;
rdfs:label "system" ;
rdfs:comment "A material entity consisting of multiple components that are causally integrated." ;
rdfs:subClassOf obo:BFO_0000040 .
obo:UBERON_0003038 a rdfs:Class ;
rdfs:label "thoracic spinal cord" ;
rdfs:comment "The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0005844 .
obo:PHIPO_0001108 a rdfs:Class ;
rdfs:label "pathogen host interaction pH phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the pH in a pathogen or host cell or cellular component." ;
rdfs:subClassOf obo:PHIPO_0000510 .
obo:GO_0014013 a rdfs:Class ;
rdfs:label "regulation of gliogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia." ;
rdfs:subClassOf obo:GO_0050767 , obo:GO_0065007 .
obo:UBERON_0004061 a rdfs:Class ;
rdfs:label "neural tube mantle layer" ;
rdfs:comment "The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer." ;
rdfs:subClassOf obo:UBERON_0005291 , obo:UBERON_0034707 .
obo:UBERON_0003489 a rdfs:Class ;
rdfs:label "respiratory system capillary endothelium" ;
rdfs:comment "An endothelium of capillary that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001915 , obo:UBERON_0004702 .
obo:GO_0031128 a rdfs:Class ;
rdfs:label "developmental induction" ;
rdfs:comment "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." ;
rdfs:subClassOf obo:GO_0032502 .
obo:GO_0007338 a rdfs:Class ;
rdfs:label "single fertilization" ;
rdfs:comment "The union of male and female gametes to form a zygote." ;
rdfs:subClassOf obo:GO_0009566 .
obo:GO_0004977 a rdfs:Class ;
rdfs:label "melanocortin receptor activity" ;
rdfs:comment "Combining with melanocortin to initiate a change in cell activity." ;
rdfs:subClassOf obo:GO_0008528 .
obo:GO_0006405 a rdfs:Class ;
rdfs:label "RNA export from nucleus" ;
rdfs:comment "The directed movement of RNA from the nucleus to the cytoplasm." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0050658 , obo:GO_0051168 .
obo:UBERON_0007288 a rdfs:Class ;
rdfs:label "presumptive forebrain midbrain boundary" ;
rdfs:comment "A presumptive structure that has the potential to develop into a forebrain-midbrain boundary." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:PATO_0002422 a rdfs:Class ;
rdfs:label "acinar" ;
rdfs:comment "Pertaining to the individual parts making up an aggregate fruit like a many-lobed \"berry,\" such as a raspberry." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:UBERON_0004225 a rdfs:Class ;
rdfs:label "respiratory system smooth muscle" ;
rdfs:comment "A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 .
obo:PHIPO_0000793 a rdfs:Class ;
rdfs:label "sensitive to anidulafungin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to anidulafungin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0002350 a rdfs:Class ;
rdfs:label "conducting system of heart" ;
rdfs:comment "The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO]." ;
rdfs:subClassOf obo:UBERON_0004493 , obo:UBERON_0010131 .
obo:GO_0003231 a rdfs:Class ;
rdfs:label "cardiac ventricle development" ;
rdfs:comment "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." ;
rdfs:subClassOf obo:GO_0003205 , obo:GO_0048856 .
obo:CL_0002078 a rdfs:Class ;
rdfs:label "meso-epithelial cell" ;
rdfs:comment "Epithelial cell derived from mesoderm or mesenchyme." ;
rdfs:subClassOf obo:CL_0000066 .
obo:GO_0098666 a rdfs:Class ;
rdfs:label "G protein-coupled serotonin receptor complex" ;
rdfs:comment "A protein complex that is capable of G protein-coupled serotonin receptor activity." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0043235 .
obo:CHEBI_35875 a rdfs:Class ;
rdfs:label "imidazopyrimidine" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_33833 , obo:CHEBI_38101 .
obo:UBERON_0002307 a rdfs:Class ;
rdfs:label "choroid plexus of lateral ventricle" ;
rdfs:comment "Part of choroid plexus contained in the lateral ventricle." ;
rdfs:subClassOf obo:UBERON_0001886 .
obo:CHEBI_50012 a rdfs:Class ;
rdfs:label "4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonate" ;
rdfs:comment "An arenesulfonate arising from deprotonation of the sulfo groups of 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonic acid." ;
rdfs:subClassOf obo:CHEBI_22713 .
obo:PHIPO_0000561 a rdfs:Class ;
rdfs:label "resistance to tylosin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tylosin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0006939 a rdfs:Class ;
rdfs:label "smooth muscle contraction" ;
rdfs:comment "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." ;
rdfs:subClassOf obo:GO_0006936 .
obo:UBERON_0002385 a rdfs:Class ;
rdfs:label "muscle tissue" ;
rdfs:comment "Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]." ;
rdfs:subClassOf obo:UBERON_0000479 , obo:UBERON_0004120 .
obo:UBERON_0036215 a rdfs:Class ;
rdfs:label "anatomical surface region" ;
rdfs:comment "Material anatomical entity that forms the outermost boundary of an anatomical structure." ;
rdfs:subClassOf obo:UBERON_0000001 .
obo:GO_0065010 a rdfs:Class ;
rdfs:label "extracellular membrane-bounded organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." ;
rdfs:subClassOf obo:GO_0043227 , obo:GO_0043230 .
obo:GO_0002824 a rdfs:Class ;
rdfs:label "positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." ;
rdfs:subClassOf obo:GO_0002821 , obo:GO_0002822 , obo:GO_0065007 .
obo:UBERON_0009032 a rdfs:Class ;
rdfs:label "right pulmonary vein" ;
rdfs:comment "Vein that drains right lung and returns blood to the heart." ;
rdfs:subClassOf obo:UBERON_0002016 .
obo:GO_0070341 a rdfs:Class ;
rdfs:label "fat cell proliferation" ;
rdfs:comment "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat." ;
rdfs:subClassOf obo:GO_0008283 .
obo:GO_0043555 a rdfs:Class ;
rdfs:label "regulation of translation in response to stress" ;
rdfs:comment "Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0065007 .
obo:CHEBI_24860 a rdfs:Class ;
rdfs:label "iodine molecular entity" ;
rdfs:subClassOf obo:CHEBI_24471 .
obo:UBERON_0003291 a rdfs:Class ;
rdfs:label "meninx of hindbrain" ;
rdfs:comment "A meninx that is part of a hindbrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002360 , obo:UBERON_0003547 .
obo:GO_0030154 a rdfs:Class ;
rdfs:label "cell differentiation" ;
rdfs:comment "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." ;
rdfs:subClassOf obo:GO_0048869 .
obo:UBERON_0004880 a rdfs:Class ;
rdfs:label "chordamesoderm" ;
rdfs:comment "The central region of trunk mesoderm. This tissue forms the notochord." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0099569 a rdfs:Class ;
rdfs:label "presynaptic cytoskeleton" ;
rdfs:comment "The portion of the cytoskeleton contained within the presynapse." ;
rdfs:subClassOf obo:GO_0005856 .
obo:UBERON_0001421 a rdfs:Class ;
rdfs:label "pectoral girdle region" ;
rdfs:comment "An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions." ;
rdfs:subClassOf obo:UBERON_0007823 , obo:UBERON_0015212 .
obo:GO_0010830 a rdfs:Class ;
rdfs:label "regulation of myotube differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ;
rdfs:subClassOf obo:GO_0051153 , obo:GO_0065007 .
a rdfs:Class ;
rdfs:label "VIP" ;
rdfs:subClassOf obo:SO_0000704 .
obo:PHIPO_0000158 a rdfs:Class ;
rdfs:label "binding phenotype"@en ;
rdfs:comment "A single species phenotype that affects the binding of a gene product to another substance. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000411 .
obo:CHEBI_38106 a rdfs:Class ;
rdfs:label "organosulfur heterocyclic compound" ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33261 .
obo:GO_0030425 a rdfs:Class ;
rdfs:label "dendrite" ;
rdfs:comment "A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body." ;
rdfs:subClassOf obo:GO_0043005 .
obo:CL_0010011 a rdfs:Class ;
rdfs:label "cerebral cortex GABAergic interneuron" ;
rdfs:comment "A GABAergic interneuron whose soma is located in the cerebral cortex." ;
rdfs:subClassOf obo:CL_0008031 , obo:CL_0011005 .
obo:CHEBI_39142 a rdfs:Class ;
rdfs:label "Bronsted base" ;
rdfs:comment "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." ;
rdfs:subClassOf obo:CHEBI_15339 , obo:CHEBI_22695 .
obo:GO_1905149 a rdfs:Class ;
rdfs:label "positive regulation of smooth muscle hypertrophy" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy." ;
rdfs:subClassOf obo:GO_0014742 , obo:GO_0014744 , obo:GO_0065007 , obo:GO_1905147 .
obo:UBERON_0035403 a rdfs:Class ;
rdfs:label "hypophysial artery" ;
rdfs:comment "An artery that supplies the pituitary gland." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:CL_0002092 a rdfs:Class ;
rdfs:label "bone marrow cell" ;
rdfs:comment "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." ;
rdfs:subClassOf obo:CL_0001035 .
obo:UBERON_0003611 a rdfs:Class ;
rdfs:label "respiratory system elastic tissue" ;
rdfs:comment "An elastic tissue that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002521 , obo:UBERON_0003570 .
obo:CL_4052017 a rdfs:Class ;
rdfs:label "choroid plexus capillary endothelial cell" ;
rdfs:comment "A capillary endothelial cell that is part of the choroid plexus, characterized by its fenestrated nature with 60 to 80 nm fenestrations and lack of tight junctions. This fenestrated structure allows for the rapid delivery of water and other components, aiding in the production of cerebrospinal fluid (CSF)." ;
rdfs:subClassOf obo:CL_0000666 , obo:CL_0002144 , obo:CL_2000044 .
obo:UBERON_0000161 a rdfs:Class ;
rdfs:label "orifice" ;
rdfs:comment "Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]." ;
rdfs:subClassOf obo:UBERON_0004111 .
obo:UBERON_0003920 a rdfs:Class ;
rdfs:label "venous blood vessel" ;
rdfs:comment "A blood vessel that carries blood from the capillaries toward the heart." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:GO_0007033 a rdfs:Class ;
rdfs:label "vacuole organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0016043 .
obo:GO_0048847 a rdfs:Class ;
rdfs:label "adenohypophysis formation" ;
rdfs:comment "The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PATO_0000057 a rdfs:Class ;
rdfs:label "occurrence" ;
rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence." ;
rdfs:subClassOf obo:PATO_0002323 .
obo:CL_0000222 a rdfs:Class ;
rdfs:label "mesodermal cell" ;
rdfs:comment "A cell of the middle germ layer of the embryo." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0002321 .
obo:GO_2000282 a rdfs:Class ;
rdfs:label "regulation of amino acid biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process." ;
rdfs:subClassOf obo:GO_0006521 , obo:GO_0009889 , obo:GO_0065007 .
obo:CHEBI_50699 a rdfs:Class ;
rdfs:label "oligosaccharide" ;
rdfs:comment "A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues." ;
rdfs:subClassOf obo:CHEBI_16646 , obo:CHEBI_167559 .
obo:GO_1903706 a rdfs:Class ;
rdfs:label "regulation of hemopoiesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of hemopoiesis." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0060284 , obo:GO_0065007 , obo:GO_2000026 .
obo:PHIPO_0000598 a rdfs:Class ;
rdfs:label "resistance to pyrimethanil"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to pyrimethanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0002932 a rdfs:Class ;
rdfs:label "tendon sheath development" ;
rdfs:comment "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0061448 .
obo:GO_0051223 a rdfs:Class ;
rdfs:label "regulation of protein transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051049 , obo:GO_0065007 , obo:GO_0070201 .
obo:UBERON_0004874 a rdfs:Class ;
rdfs:label "somatopleure" ;
rdfs:comment "A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:PHIPO_0000303 a rdfs:Class ;
rdfs:label "abnormal dissemination of sexual spore"@en ;
rdfs:comment "A single species phenotype where the dispersal of sexual spores is abnormal (FAO:0000017)." ;
rdfs:subClassOf obo:PHIPO_0000043 .
obo:GO_0016053 a rdfs:Class ;
rdfs:label "organic acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage." ;
rdfs:subClassOf obo:GO_0006082 , obo:GO_0009058 , obo:GO_0044283 .
obo:GO_2001222 a rdfs:Class ;
rdfs:label "regulation of neuron migration" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuron migration." ;
rdfs:subClassOf obo:GO_0030334 , obo:GO_0065007 .
obo:UBERON_0002118 a rdfs:Class ;
rdfs:label "right ovary" ;
rdfs:comment "An ovary that is part of a right side of organism [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000992 , obo:UBERON_0015212 .
obo:GO_1901881 a rdfs:Class ;
rdfs:label "positive regulation of protein depolymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein depolymerization." ;
rdfs:subClassOf obo:GO_0043243 , obo:GO_0065007 , obo:GO_1901879 .
obo:CHEBI_231553 a rdfs:Class ;
rdfs:label "levofloxacin(1-)" ;
rdfs:comment "An oxo monocarboxylic acid anion that is the conjugate base of levofloxacin resulting from the deprotonation of the carboxy group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35902 .
obo:UBERON_0016458 a rdfs:Class ;
rdfs:label "esophageal hiatus" ;
rdfs:comment "A hole in the diaphragm through which the esophagus passes." ;
rdfs:subClassOf obo:UBERON_0000161 .
obo:GO_2000380 a rdfs:Class ;
rdfs:label "regulation of mesoderm development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mesoderm development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_1903426 a rdfs:Class ;
rdfs:label "regulation of reactive oxygen species biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0065007 , obo:GO_2000377 .
obo:CHEBI_29013 a rdfs:Class ;
rdfs:label "fusidic acid" ;
rdfs:comment "A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum." ;
rdfs:subClassOf obo:CHEBI_19129 , obo:CHEBI_26761 , obo:CHEBI_35915 , obo:CHEBI_36835 , obo:CHEBI_47891 , obo:CHEBI_79020 .
obo:PR_000029968 a rdfs:Class ;
rdfs:label "somatotropin hormone family member" ;
rdfs:comment "A protein that is a standalone version of the Hormone_1 domain (Pfam:PF00103). In the immature form, the domain is preceded by a signal peptide." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PHIPO_0000263 a rdfs:Class ;
rdfs:label "abnormal nuclear transport"@en ;
rdfs:comment "A single organism cellular process phenotype in which nuclear transport is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000257 , obo:PHIPO_0000929 .
obo:PHIPO_0000804 a rdfs:Class ;
rdfs:label "sensitive to strobilurin A"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to strobilurin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0002974 a rdfs:Class ;
rdfs:label "molecular layer of cerebellar cortex" ;
rdfs:comment "The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." ;
rdfs:subClassOf obo:UBERON_0004130 .
obo:UBERON_0006909 a rdfs:Class ;
rdfs:label "lumen of digestive tract" ;
rdfs:comment "An anatomical space that surrounded_by a digestive tract." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0003300 a rdfs:Class ;
rdfs:label "cardiac muscle hypertrophy" ;
rdfs:comment "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division." ;
rdfs:subClassOf obo:GO_0014897 .
obo:UBERON_0001005 a rdfs:Class ;
rdfs:label "respiratory airway" ;
rdfs:comment "An airway through which respiratory air passes in organisms." ;
rdfs:subClassOf obo:UBERON_0003103 , obo:UBERON_0004111 .
obo:CHEBI_33257 a rdfs:Class ;
rdfs:label "secondary amide" ;
rdfs:comment "A derivative of two oxoacids RkE(=O)l(OH)m (l ≠ 0) in which two acyl groups are attached to the amino or substituted amino group." ;
rdfs:subClassOf obo:CHEBI_32988 .
obo:CHEBI_4998 a rdfs:Class ;
rdfs:label "fenarimol" ;
rdfs:comment "A racemate comprising equimolar amounts of (R)- and (S)-fenarimol. A sterol demethylation inhibitor, it is used as a fungicide for the treatment of blackspot, mildew and rust in tomatoes, peppers and melons, but is not approved for use within the European Union." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87207 .
obo:PHIPO_0000277 a rdfs:Class ;
rdfs:label "obsolete abnormal filamentous growth" .
obo:GO_0099515 a rdfs:Class ;
rdfs:label "actin filament-based transport" ;
rdfs:comment "The transport of organelles or other particles from one location in the cell to another along actin filaments." ;
rdfs:subClassOf obo:GO_0030705 , obo:GO_0046907 .
obo:GO_0045663 a rdfs:Class ;
rdfs:label "positive regulation of myoblast differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0045661 , obo:GO_0065007 .
obo:PHIPO_0000288 a rdfs:Class ;
rdfs:label "decreased cellular pigment accumulation"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of coloring matter in a cell is decreased." ;
rdfs:subClassOf obo:PHIPO_0000285 , obo:PHIPO_0000929 .
obo:PR_Q9D387 a rdfs:Class ;
rdfs:label "lysosome-associated membrane glycoprotein 5 (mouse)" ;
rdfs:comment "A lysosome-associated membrane glycoprotein 5 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000029032 , obo:PR_000032148 .
obo:GO_0010614 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle hypertrophy" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." ;
rdfs:subClassOf obo:GO_0010611 , obo:GO_0014741 , obo:GO_0065007 .
obo:CL_0000056 a rdfs:Class ;
rdfs:label "myoblast" ;
rdfs:comment "A cell that is committed to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair." ;
rdfs:subClassOf obo:CL_0000680 .
obo:PHIPO_0001003 a rdfs:Class ;
rdfs:label "normal formation of extra-invasive hyphal membrane"@en ;
rdfs:comment "A pathogen host interaction phenotype where the morphology of the host extra-invasive hyphal membrane (GO:0085039) during pathogen invasion is normal (indistinguishable from wild type). This relates to the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0001005 .
obo:UBERON_0014477 a rdfs:Class ;
rdfs:label "thoracic skeleton" ;
rdfs:comment "Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:CHEBI_77884 a rdfs:Class ;
rdfs:label "EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor" ;
rdfs:comment "An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14α-demethylase)." ;
rdfs:subClassOf obo:CHEBI_76841 , obo:CHEBI_83734 .
obo:PHIPO_0000944 a rdfs:Class ;
rdfs:label "altered level of substance in cell"@en ;
rdfs:comment "A single species cell phenotype in which the amount of a specific substance measured in a cell differs from normal." ;
rdfs:subClassOf obo:PHIPO_0000404 .
obo:CHEBI_25741 a rdfs:Class ;
rdfs:label "oxide" ;
rdfs:comment "An oxide is a chemical compound of oxygen with other chemical elements." ;
rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_37577 .
obo:UBERON_0002063 a rdfs:Class ;
rdfs:label "sinus venosus" ;
rdfs:comment "The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0004151 .
obo:PHIPO_0000872 a rdfs:Class ;
rdfs:label "sensitive to copper"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to copper. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0101025 a rdfs:Class ;
rdfs:label "nuclear membrane biogenesis" ;
rdfs:comment "The process in which a nuclear membrane is synthesized, aggregates, and bonds together." ;
rdfs:subClassOf obo:GO_0044085 , obo:GO_0044091 .
obo:GO_0006997 a rdfs:Class ;
rdfs:label "nucleus organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0016043 .
obo:PHIPO_0000081 a rdfs:Class ;
rdfs:label "abnormal asexual spore size"@en ;
rdfs:comment "A reproductive morphology phenotype where the size of the asexual spore is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000127 .
obo:CHEBI_59635 a rdfs:Class ;
rdfs:label "organophosphonate oxoanion" ;
rdfs:comment "An organic phosphonic acid derivative in which one or more oxygen atoms of the phosphonate group(s) has been deprotonated." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_36360 .
obo:GO_1902338 a rdfs:Class ;
rdfs:label "negative regulation of apoptotic process involved in morphogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904746 .
obo:PHIPO_0001372 a rdfs:Class ;
rdfs:label "normal growth on pyrimorph" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrimorph (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PHIPO_0000753 a rdfs:Class ;
rdfs:label "sensitive to ceftriaxone"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ceftriaxone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000788 a rdfs:Class ;
rdfs:label "sensitive to fosfomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fosfomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0003380 a rdfs:Class ;
rdfs:label "establishment or maintenance of cytoskeleton polarity involved in gastrulation" ;
rdfs:comment "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation." ;
rdfs:subClassOf obo:GO_0003371 , obo:GO_0030952 .
obo:CHEBI_51374 a rdfs:Class ;
rdfs:label "GABA agent" ;
rdfs:comment "A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems." ;
rdfs:subClassOf obo:CHEBI_35942 .
obo:PHIPO_0001019 a rdfs:Class ;
rdfs:label "decreased rate of asexual spore germination"@en ;
rdfs:comment "A cellular process phenotype in which the rate, or speed, of asexual spore germination is decreased." ;
rdfs:subClassOf obo:PHIPO_0000929 , obo:PHIPO_0001018 .
obo:GO_0044092 a rdfs:Class ;
rdfs:label "negative regulation of molecular function" ;
rdfs:comment "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0065009 .
obo:GO_0034391 a rdfs:Class ;
rdfs:label "regulation of smooth muscle cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process." ;
rdfs:subClassOf obo:GO_0010660 , obo:GO_0065007 .
obo:CHEBI_35604 a rdfs:Class ;
rdfs:label "carbon oxoanion" ;
rdfs:comment "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOyn− for some integers x, y and n." ;
rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_35406 , obo:CHEBI_36963 .
obo:UBERON_0003852 a rdfs:Class ;
rdfs:label "rhombencephalon neural crest" ;
rdfs:comment "A neural crest that has_potential_to_developmentally_contribute_to a hindbrain." ;
rdfs:subClassOf obo:UBERON_0002342 , obo:UBERON_0003099 .
obo:GO_1905192 a rdfs:Class ;
rdfs:label "regulation of chloroplast fission" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of chloroplast fission." ;
rdfs:subClassOf obo:GO_0033043 , obo:GO_0065007 .
obo:GO_0010958 a rdfs:Class ;
rdfs:label "regulation of amino acid import across plasma membrane" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of amino acid import into a cell." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903789 .
obo:PATO_0000068 a rdfs:Class ;
rdfs:label "qualitative" ;
rdfs:comment "A quality of an entity that is descriptive or observational, typically not represented numerically." ;
rdfs:subClassOf obo:PATO_0000001 .
obo:UBERON_0001897 a rdfs:Class ;
rdfs:label "dorsal plus ventral thalamus" ;
rdfs:comment "Subcortical brain region consisting of paired gray matter bodies in the dorsal diencephalon and forming part of the lateral wall of the third ventricle of the brain. The thalamus represents the major portion of the diencephalon and is commonly divided into cellular aggregates known as nuclear groups.(MeSH). The dorsal topographic division of the interbrain. The macrodissected adult human thalamus was clearly illustrated by Vesalius in 1543 and the term as defined here was introduced by His in 1893. It includes the traditional epithalamus, dorsal thalamus, and ventral thalamus of Herrick (1910, pp. 494, 498). Also see Kuhlenbeck (1927, Ch. 9) and Jones (1985, p. 87)." ;
rdfs:subClassOf obo:UBERON_0002616 , obo:UBERON_0015212 .
obo:CL_0002421 a rdfs:Class ;
rdfs:label "nucleated reticulocyte" ;
rdfs:comment "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles." ;
rdfs:subClassOf obo:CL_0000558 , obo:CL_0002242 .
obo:PHIPO_0000126 a rdfs:Class ;
rdfs:label "premature pathogen penetration across the barrier"@en ;
rdfs:comment "A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration begins sooner than normal when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000024 .
obo:PHIPO_0000214 a rdfs:Class ;
rdfs:label "increased pathogen host protein-protein interaction"@en ;
rdfs:comment "A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs to a greater extent than normal." ;
rdfs:subClassOf obo:PHIPO_0001106 .
obo:CHEBI_59668 a rdfs:Class ;
rdfs:label "nikkomycin" ;
rdfs:comment "A class of nucleoside-peptide antibiotics which inhibit fungal chitin biosynthesis by inhibiting chitin synthase. Generally consist of a heterocyclic moiety (usually a nucleobase), an amino hexuronic acid and an amino acid containing a pyridine ring." ;
rdfs:subClassOf obo:CHEBI_36988 .
obo:CHEBI_48001 a rdfs:Class ;
rdfs:label "protein synthesis inhibitor" ;
rdfs:comment "A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein." ;
rdfs:subClassOf obo:CHEBI_76932 .
obo:GO_0048522 a rdfs:Class ;
rdfs:label "positive regulation of cellular process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0051252 a rdfs:Class ;
rdfs:label "regulation of RNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." ;
rdfs:subClassOf obo:GO_0019219 , obo:GO_0060255 , obo:GO_0065007 .
obo:GO_0003278 a rdfs:Class ;
rdfs:label "apoptotic process involved in heart morphogenesis" ;
rdfs:comment "Any apoptotic process that contributes to the shaping of the heart." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0060561 .
obo:UBERON_0036288 a rdfs:Class ;
rdfs:label "anterior wall of left ventricle" ;
rdfs:subClassOf obo:UBERON_0004784 , obo:UBERON_0036285 .
obo:CL_0001066 a rdfs:Class ;
rdfs:label "erythroid progenitor cell, mammalian" ;
rdfs:comment "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative)." ;
rdfs:subClassOf obo:CL_0000038 .
obo:GO_0075052 a rdfs:Class .
obo:UBERON_0007524 a rdfs:Class ;
rdfs:label "dense mesenchyme tissue" ;
rdfs:comment "Mesenchyme with little extracellular matrix." ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:GO_0002009 a rdfs:Class ;
rdfs:label "morphogenesis of an epithelium" ;
rdfs:comment "The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048729 .
a rdfs:Class ;
rdfs:label "LINC00298" ;
rdfs:subClassOf obo:SO_0000704 .
obo:GO_0032528 a rdfs:Class ;
rdfs:label "microvillus organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0120036 .
obo:UBERON_0011156 a rdfs:Class ;
rdfs:label "facial skeleton" ;
rdfs:comment "Subdivision of skull that consists of the facial bones." ;
rdfs:subClassOf obo:UBERON_0010313 , obo:UBERON_0011158 .
obo:UBERON_0010256 a rdfs:Class ;
rdfs:label "4th arch mesenchyme from neural crest" ;
rdfs:comment "Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005691 , obo:UBERON_0010258 , obo:UBERON_0010359 .
obo:CL_4307044 a rdfs:Class ;
rdfs:label "Astro-TE NN_3 Cxcl5 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Cxcl5 (Mmus), Ddn (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Cxcl5, Kif5a. These cells are located in the Hippocampal region, Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5224 Astro-TE NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301593 .
obo:UBERON_0004800 a rdfs:Class ;
rdfs:label "bronchus basal lamina" ;
rdfs:comment "A basal lamina that is part of a bronchus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000482 , obo:UBERON_0004799 .
obo:CHEBI_77718 a rdfs:Class ;
rdfs:label "carboxamidinium ion" ;
rdfs:comment "Any iminium ion resulting from the protonation of a carboxamidine." ;
rdfs:subClassOf obo:CHEBI_35286 .
obo:CL_4307094 a rdfs:Class ;
rdfs:label "COP NN_1 C1ql1 committed oligodendrocyte precursor (Mmus)" ;
rdfs:comment "A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bgn (Mmus), Gstp1 (Mmus), C1ql1 (Mmus). It is distinguished from other COP NN_1 cells by expression of C1ql1, Gstp1. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5274 COP NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301611 .
obo:GO_0051033 a rdfs:Class ;
rdfs:label "RNA transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 , obo:GO_0051032 .
obo:PHIPO_0001364 a rdfs:Class ;
rdfs:label "normal growth on isopyrazam" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to isopyrazam (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PR_P08508 a rdfs:Class ;
rdfs:label "low affinity immunoglobulin gamma Fc region receptor III (mouse)" ;
rdfs:comment "A low affinity immunoglobulin gamma Fc region receptor III that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001483 , obo:PR_000029032 .
obo:GO_0046885 a rdfs:Class ;
rdfs:label "regulation of hormone biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0032350 , obo:GO_0065007 .
obo:GO_0009308 a rdfs:Class ;
rdfs:label "amine metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0035082 a rdfs:Class ;
rdfs:label "axoneme assembly" ;
rdfs:comment "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." ;
rdfs:subClassOf obo:GO_0001578 , obo:GO_0022607 .
obo:GO_1903010 a rdfs:Class ;
rdfs:label "regulation of bone development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of bone development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000026 .
obo:GO_0044346 a rdfs:Class ;
rdfs:label "fibroblast apoptotic process" ;
rdfs:comment "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." ;
rdfs:subClassOf obo:GO_0006915 .
obo:GO_0061881 a rdfs:Class ;
rdfs:label "positive regulation of anterograde axonal transport of mitochondrion" ;
rdfs:comment "Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0061880 , obo:GO_0065007 .
obo:PHIPO_0001176 a rdfs:Class ;
rdfs:label "effector-mediated immune suppression phenotype"@en ;
rdfs:comment "A phenotype dependent on an interaction between a pathogen effector and a host process in order for the pathogen to suppress the host immune system. An effector is an entity derived from a pathogenic or non-pathogenic species that either activates or suppresses host defenses or other host responses." ;
rdfs:subClassOf obo:PHIPO_0000280 .
obo:PHIPO_0000347 a rdfs:Class ;
rdfs:label "pathogen host interaction molecular function phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype that affects a molecular function such as binding or catalytic activity." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:CL_1001581 a rdfs:Class ;
rdfs:label "lateral ventricle glial cell" ;
rdfs:comment "Glial cell of lateral ventricle." ;
rdfs:subClassOf obo:CL_0000125 .
obo:GO_0045682 a rdfs:Class ;
rdfs:label "regulation of epidermis development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of epidermis development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_1900409 a rdfs:Class ;
rdfs:label "positive regulation of cellular response to oxidative stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress." ;
rdfs:subClassOf obo:GO_0048522 , obo:GO_0065007 , obo:GO_1900407 , obo:GO_1902884 .
obo:CHEBI_18154 a rdfs:Class ;
rdfs:label "polysaccharide" ;
rdfs:comment "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." ;
rdfs:subClassOf obo:CHEBI_16646 , obo:CHEBI_167559 , obo:CHEBI_33694 .
obo:CHEBI_6827 a rdfs:Class ;
rdfs:label "methicillin" ;
rdfs:comment "A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 2,6-dimethoxybenzoyl group." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_88187 .
obo:GO_0035904 a rdfs:Class ;
rdfs:label "aorta development" ;
rdfs:comment "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060840 .
obo:UBERON_0004798 a rdfs:Class ;
rdfs:label "respiratory system basal lamina" ;
rdfs:comment "A basal lamina that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000482 .
obo:GO_0005759 a rdfs:Class ;
rdfs:label "mitochondrial matrix" ;
rdfs:comment "The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation." ;
rdfs:subClassOf obo:GO_0070013 .
obo:GO_0043934 a rdfs:Class ;
rdfs:label "sporulation" ;
rdfs:comment "The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction." ;
rdfs:subClassOf obo:GO_0032502 .
obo:GO_0048854 a rdfs:Class ;
rdfs:label "brain morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:GO_0016020 a rdfs:Class ;
rdfs:label "membrane" ;
rdfs:comment "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0007492 a rdfs:Class ;
rdfs:label "endoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." ;
rdfs:subClassOf obo:GO_0009888 , obo:GO_0048856 .
obo:GO_0061559 a rdfs:Class ;
rdfs:label "cranial ganglion morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of a cranial ganglion is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0061552 .
obo:PHIPO_0000466 a rdfs:Class ;
rdfs:label "obsolete host necrotic cell death by pathogen induced hypersensitive response" ;
rdfs:comment "A phenotype that affects the immune system process of host necrotic cell death by pathogen induced hypersensitive response. Pathogen induced hypersensitive response is the rapid, localized death of plant cells in response to invasion by a pathogen (GO:0009626)." .
obo:CL_0000211 a rdfs:Class ;
rdfs:label "electrically active cell" ;
rdfs:comment "A cell whose function is determined by the generation or the reception of an electric signal." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0001700 a rdfs:Class ;
rdfs:label "embryonic development via the syncytial blastoderm" ;
rdfs:comment "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0009792 .
obo:UBERON_0000479 a rdfs:Class ;
rdfs:label "tissue" ;
rdfs:comment "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:CHEBI_51121 a rdfs:Class ;
rdfs:label "fluorescent dye" ;
rdfs:subClassOf obo:CHEBI_37958 .
obo:CL_4301591 a rdfs:Class ;
rdfs:label "Astro-TE NN_1 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Camk2a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1161 Astro-TE NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300359 .
obo:CL_0002132 a rdfs:Class ;
rdfs:label "stromal cell of ovary" ;
rdfs:comment "A stomal cell of the ovary" ;
rdfs:subClassOf obo:CL_0000499 .
obo:CL_4023059 a rdfs:Class ;
rdfs:label "committed oligodendrocyte precursor" ;
rdfs:comment "An oligodendrocyte precursor cell that is committed to differentiate." ;
rdfs:subClassOf obo:CL_0000123 .
obo:CL_4072001 a rdfs:Class ;
rdfs:label "newly formed oligodendrocyte"@en ;
rdfs:comment "A post-mitotic oligodendrocyte that has exited the cell cycle and begun early stage differentiation. The cell begins to acquire oligodendrocyte-like characteristics but has not yet initiated myelination. In mice, NFOL is marked by the expression of Tcf7l2 and Cemip2 (also known as Tmem2), among other early myelin-related genes. These markers highlight cells transitioning from a precursor to a more differentiated, pre-myelinating state." ;
rdfs:subClassOf obo:CL_0000123 , obo:CL_0000128 .
obo:CL_4030049 a rdfs:Class ;
rdfs:label "striosomal D2 medium spiny neuron" ;
rdfs:comment "A DRD2-expressing medium spiny neuron that is part of a striosome of dorsal striatum." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_4023029 .
obo:CHEBI_30096 a rdfs:Class ;
rdfs:label "diazene" ;
rdfs:subClassOf obo:CHEBI_35106 .
obo:GO_0060143 a rdfs:Class ;
rdfs:label "positive regulation of syncytium formation by plasma membrane fusion" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0060142 , obo:GO_0065007 .
obo:GO_1905278 a rdfs:Class ;
rdfs:label "positive regulation of epithelial tube formation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of epithelial tube formation." ;
rdfs:subClassOf obo:GO_0051240 , obo:GO_0065007 , obo:GO_1905276 , obo:GO_1905332 .
obo:GO_0055018 a rdfs:Class ;
rdfs:label "regulation of cardiac muscle fiber development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development." ;
rdfs:subClassOf obo:GO_0060284 , obo:GO_0065007 , obo:GO_2000725 .
obo:CHEBI_81923 a rdfs:Class ;
rdfs:label "flutriafol" ;
rdfs:comment "A racemate comprising an equimolar mixture of (R)- and (S)-flutriafol. A systemic fungicide, it is used to control fungal diseases in cereal crops." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87067 , obo:CHEBI_87100 .
obo:GO_0098690 a rdfs:Class ;
rdfs:label "glycinergic synapse" ;
rdfs:comment "A synapse that uses glycine as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0045202 .
obo:GO_1902473 a rdfs:Class ;
rdfs:label "regulation of protein localization to synapse" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to synapse." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_0015800 a rdfs:Class ;
rdfs:label "acidic amino acid transport" ;
rdfs:comment "The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006865 .
a rdfs:Class ;
rdfs:label "Striatum ventral region" ;
rdfs:subClassOf , obo:UBERON_0005403 .
obo:PR_000002062 a rdfs:Class ;
rdfs:label "macrophage colony-stimulating factor 1 receptor" ;
rdfs:comment "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human CSF1R gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001810 .
obo:PATO_0002094 a rdfs:Class ;
rdfs:label "basophilic" ;
rdfs:comment "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions." ;
rdfs:subClassOf obo:PATO_0070045 .
obo:UBERON_0002257 a rdfs:Class ;
rdfs:label "ventral horn of spinal cord" ;
rdfs:comment "The ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]." ;
rdfs:subClassOf obo:UBERON_0015212 , obo:UBERON_0016550 .
obo:GO_0030187 a rdfs:Class ;
rdfs:label "melatonin biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine)." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0030186 , obo:GO_0042435 , obo:GO_0042446 .
obo:UBERON_0003236 a rdfs:Class ;
rdfs:label "epithelium of lower jaw" ;
rdfs:comment "An epithelium that is part of a lower jaw [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0035037 .
obo:GO_0048583 a rdfs:Class ;
rdfs:label "regulation of response to stimulus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:CHEBI_33247 a rdfs:Class ;
rdfs:label "organic group" ;
rdfs:comment "Any substituent group or skeleton containing carbon." ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:GO_2001204 a rdfs:Class ;
rdfs:label "regulation of osteoclast development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of osteoclast development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903706 .
obo:UBERON_0009611 a rdfs:Class ;
rdfs:label "midbrain neural plate" ;
rdfs:comment "A neural plate that develops_from a presumptive midbrain." ;
rdfs:subClassOf obo:UBERON_0003075 .
obo:CHEBI_37416 a rdfs:Class ;
rdfs:label "EC 2.7.7.6 (RNA polymerase) inhibitor" ;
rdfs:comment "An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6)." ;
rdfs:subClassOf obo:CHEBI_76815 .
obo:GO_0034330 a rdfs:Class ;
rdfs:label "cell junction organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." ;
rdfs:subClassOf obo:GO_0016043 .
obo:CHEBI_51269 a rdfs:Class ;
rdfs:label "acenes" ;
rdfs:comment "Polycyclic aromatic hydrocarbons consisting of fused benzene rings in a rectilinear arrangement and their substitution derivatives." ;
rdfs:subClassOf obo:CHEBI_33836 .
obo:GO_0060249 a rdfs:Class ;
rdfs:label "anatomical structure homeostasis" ;
rdfs:comment "A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ;
rdfs:subClassOf obo:GO_0048871 .
obo:CHEBI_25355 a rdfs:Class ;
rdfs:label "mitochondrial respiratory-chain inhibitor" ;
rdfs:subClassOf obo:CHEBI_38497 .
obo:UBERON_0008780 a rdfs:Class ;
rdfs:label "inner cell mass derived epiblast" ;
rdfs:comment "An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers." ;
rdfs:subClassOf obo:UBERON_0002532 .
obo:CHEBI_39219 a rdfs:Class ;
rdfs:label "avermectin acaricide" ;
rdfs:subClassOf obo:CHEBI_39218 , obo:CHEBI_39220 .
obo:CHEBI_176497 a rdfs:Class ;
rdfs:label "geroprotector" ;
rdfs:comment "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan." ;
rdfs:subClassOf obo:CHEBI_50267 .
obo:UBERON_0006003 a rdfs:Class ;
rdfs:label "integumentary adnexa" ;
rdfs:comment "Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:CHEBI_83146 a rdfs:Class ;
rdfs:label "Daphnia tenebrosa metabolite" ;
rdfs:comment "A Daphnia metabolite produced by the species Daphnia tenebrosa." ;
rdfs:subClassOf obo:CHEBI_83057 .
obo:PHIPO_0001294 a rdfs:Class ;
rdfs:label "inhibition of pathogen polygalacturonase by host present"@en ;
rdfs:comment "A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen polygalacturonase is present." ;
rdfs:subClassOf obo:PHIPO_0000347 .
obo:GO_1905690 a rdfs:Class ;
rdfs:label "nucleus disassembly" ;
rdfs:comment "The disaggregation of a nucleus into its constituent components." ;
rdfs:subClassOf obo:GO_0006997 , obo:GO_0022411 , obo:GO_1903008 .
obo:GO_0045939 a rdfs:Class ;
rdfs:label "negative regulation of steroid metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids." ;
rdfs:subClassOf obo:GO_0019218 , obo:GO_0045833 , obo:GO_0065007 .
obo:GO_0016594 a rdfs:Class ;
rdfs:label "glycine binding" ;
rdfs:comment "Binding to glycine, aminoethanoic acid." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0016597 , obo:GO_0031406 , obo:GO_0043169 .
obo:GO_0010463 a rdfs:Class ;
rdfs:label "mesenchymal cell proliferation" ;
rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ;
rdfs:subClassOf obo:GO_0008283 .
obo:GO_0021679 a rdfs:Class ;
rdfs:label "cerebellar molecular layer development" ;
rdfs:comment "The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_26607 a rdfs:Class ;
rdfs:label "saturated fatty acid" ;
rdfs:comment "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:CL_0000667 a rdfs:Class ;
rdfs:label "collagen secreting cell" ;
rdfs:comment "An extracellular matrix secreting cell that secretes collagen." ;
rdfs:subClassOf obo:CL_0000327 .
obo:GO_7770058 a rdfs:Class ;
rdfs:label "mitochondrial protein import pathway" ;
rdfs:comment "The import of proteins from the cytosol to their final destination in the mitochondria." ;
rdfs:subClassOf obo:GO_0006839 .
obo:UBERON_0014636 a rdfs:Class ;
rdfs:label "thoracic spinal cord gray matter" ;
rdfs:comment "A gray matter of spinal cord that is part of a thoracic spinal cord." ;
rdfs:subClassOf obo:UBERON_0002315 .
obo:CHEBI_38632 a rdfs:Class ;
rdfs:label "membrane transport modulator" ;
rdfs:comment "Any agent that affects the transport of molecular entities across a biological membrane." ;
rdfs:subClassOf obo:CHEBI_52208 .
obo:CHEBI_18367 a rdfs:Class ;
rdfs:label "phosphate(3-)" ;
rdfs:comment "A phosphate ion that is the conjugate base of hydrogenphosphate." ;
rdfs:subClassOf obo:CHEBI_35780 , obo:CHEBI_79387 .
obo:UBERON_0006136 a rdfs:Class ;
rdfs:label "unmyelinated nerve fiber" ;
rdfs:subClassOf obo:UBERON_0006134 .
obo:GO_0051656 a rdfs:Class ;
rdfs:label "establishment of organelle localization" ;
rdfs:comment "The directed movement of an organelle to a specific location." ;
rdfs:subClassOf obo:GO_0051234 , obo:GO_0051640 .
obo:GO_0140115 a rdfs:Class ;
rdfs:label "export across plasma membrane" ;
rdfs:comment "The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0055085 , obo:GO_0140352 .
obo:PHIPO_0000775 a rdfs:Class ;
rdfs:label "sensitive to flucytosine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to flucytosine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0050673 a rdfs:Class ;
rdfs:label "epithelial cell proliferation" ;
rdfs:comment "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances." ;
rdfs:subClassOf obo:GO_0008283 .
obo:GO_0110023 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle myoblast proliferation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0110022 , obo:GO_2000818 .
obo:PHIPO_0001033 a rdfs:Class ;
rdfs:label "pyocyanin absent from cell"@en ;
rdfs:comment "A single species cell phenotype in which the amount of pyocyanin measured in a cell is too low to detect." ;
rdfs:subClassOf obo:PHIPO_0001034 .
obo:PHIPO_0001329 a rdfs:Class ;
rdfs:label "normal growth on fluazinam"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to fluazinam (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:UBERON_0004549 a rdfs:Class ;
rdfs:label "right eye" ;
rdfs:comment "An eye that is part of a right side of organism [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000970 , obo:UBERON_0015212 .
obo:UBERON_0005287 a rdfs:Class ;
rdfs:label "tela choroidea of fourth ventricle" ;
rdfs:comment "Tela chorioidea that lines the fourth ventricle[ZFA]. The tela chorioidea of the fourth ventricle is the name applied to the triangular fold of pia mater which is carried upward between the cerebellum and the medulla oblongata. It consists of two layers, which are continuous with each other in front, and are more or less adherent throughout: The posterior layer covers the antero-inferior surface of the cerebellum. The anterior layer is applied to the structures which form the lower part of the roof of the ventricle, and is continuous inferiorly with the pia mater on the inferior peduncles and closed part of the medulla[WP]." ;
rdfs:subClassOf obo:UBERON_0005283 .
obo:UBERON_0009662 a rdfs:Class ;
rdfs:label "hindbrain nucleus" ;
rdfs:comment "Nucleus located within the hindbrain." ;
rdfs:subClassOf obo:UBERON_0002308 .
obo:NCBITaxon_314147 a rdfs:Class ;
rdfs:label "Glires" ;
rdfs:subClassOf obo:NCBITaxon_314146 .
obo:UBERON_0010230 a rdfs:Class ;
rdfs:label "eyeball of camera-type eye" ;
rdfs:comment "The core globe-shaped component of the camera-type eye." ;
rdfs:subClassOf obo:UBERON_0000020 .
obo:CL_4310133 a rdfs:Class ;
rdfs:label "STRd D2 StrioMat Hybrid MSN indirect pathway medium spiny neuron (Primate)" ;
rdfs:comment "A indirect pathway medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 StrioMat Hybrid MSN." ;
rdfs:subClassOf obo:CL_4310059 .
obo:GO_0021768 a rdfs:Class ;
rdfs:label "nucleus accumbens development" ;
rdfs:comment "The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048857 .
obo:CHEBI_46629 a rdfs:Class ;
rdfs:label "oxo group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:CHEBI_50406 a rdfs:Class ;
rdfs:label "probe" ;
rdfs:comment "A role played by a molecular entity used to study the microscopic environment." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:CL_0002590 a rdfs:Class ;
rdfs:label "smooth muscle cell of the brain vasculature" ;
rdfs:comment "A vascular associated smooth muscle cell of the brain vasculature." ;
rdfs:subClassOf obo:CL_0000359 , obo:CL_0002319 .
obo:PHIPO_0001379 a rdfs:Class ;
rdfs:label "sensitive to tacrolimus" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tacrolimus. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0001429 a rdfs:Class ;
rdfs:label "normal growth on fluconazole"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to fluconazole (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0051216 a rdfs:Class ;
rdfs:label "cartilage development" ;
rdfs:comment "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:CHEBI_24869 a rdfs:Class ;
rdfs:label "ionophore" ;
rdfs:comment "A compound which can carry specific ions through membranes of cells or organelles." ;
rdfs:subClassOf obo:CHEBI_38632 .
obo:GO_0060497 a rdfs:Class ;
rdfs:label "mesenchymal-endodermal cell signaling" ;
rdfs:comment "Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell." ;
rdfs:subClassOf obo:GO_0007267 .
obo:CHEBI_59755 a rdfs:Class ;
rdfs:label "alpha-amino fatty acid" ;
rdfs:comment "A fatty acid with an amino substituent at position C-2." ;
rdfs:subClassOf obo:CHEBI_59650 , obo:CHEBI_83925 .
obo:CL_4310114 a rdfs:Class ;
rdfs:label "SN SEMA5A GABA GABAergic interneuron (Primate)" ;
rdfs:comment "A GABAergic interneuron of the Primates brain. These cells are located in the striatum, subthalamic nucleus, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN SEMA5A GABA." ;
rdfs:subClassOf obo:CL_0011005 , obo:CL_4310056 .
obo:CHEBI_145790 a rdfs:Class ;
rdfs:label "mupirocin(1-)" ;
rdfs:comment "A monocarboxylic acid anion that is the conjugate base of mupirocin obtained by the deprotonation of the carboxy group; major microspecies at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:CHEBI_58954 a rdfs:Class ;
rdfs:label "straight-chain saturated fatty acid anion" ;
rdfs:comment "Any saturated fatty acid anion lacking a carbon side-chain." ;
rdfs:subClassOf obo:CHEBI_58953 .
obo:GO_0031022 a rdfs:Class ;
rdfs:label "nuclear migration along microfilament" ;
rdfs:comment "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0007097 , obo:GO_0030048 , obo:GO_0099515 .
obo:CHEBI_76789 a rdfs:Class ;
rdfs:label "EC 2.4.1.* (hexosyltransferase) inhibitor" ;
rdfs:comment "An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any hexosyltransferase (EC 2.4.1.*)." ;
rdfs:subClassOf obo:CHEBI_76662 .
obo:CL_0020004 a rdfs:Class ;
rdfs:label "internal globus pallidus shell projection neuron" ;
rdfs:comment "A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi), in the peripheral 'shell' region. In mice and primates, it expresses somatostatin and shows dual expression of GABAergic and glutamatergic markers, enabling co-release of GABA and glutamate (Wallace et al., 2017). It projects primarily to the lateral habenula (Parent & De Bellefeuille, 1982; Wallace et al., 2017), forming the limbic/aversive output stream of the GPi." ;
rdfs:subClassOf obo:CL_0000617 , obo:CL_0012001 .
obo:CHEBI_25105 a rdfs:Class ;
rdfs:label "macrolide antibiotic" ;
rdfs:comment "A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity." ;
rdfs:subClassOf obo:CHEBI_25106 .
obo:UBERON_0009842 a rdfs:Class ;
rdfs:label "glandular acinus" ;
rdfs:comment "The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form." ;
rdfs:subClassOf obo:UBERON_0034922 .
obo:UBERON_0001068 a rdfs:Class ;
rdfs:label "skin of back" ;
rdfs:comment "A zone of skin that is part of a back [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0001085 .
obo:UBERON_0004852 a rdfs:Class ;
rdfs:label "cardiovascular system endothelium" ;
rdfs:comment "An endothelium that is part of the cardiovascular system." ;
rdfs:subClassOf obo:UBERON_0001986 .
obo:GO_0061548 a rdfs:Class ;
rdfs:label "ganglion development" ;
rdfs:comment "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0009888 , obo:GO_0048856 .
obo:GO_0014733 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle adaptation" ;
rdfs:comment "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." ;
rdfs:subClassOf obo:GO_0043502 , obo:GO_0065007 .
obo:GO_0033032 a rdfs:Class ;
rdfs:label "regulation of myeloid cell apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0065007 .
obo:GO_1902035 a rdfs:Class ;
rdfs:label "positive regulation of hematopoietic stem cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902033 , obo:GO_2000648 .
obo:UBERON_2005260 a rdfs:Class ;
rdfs:label "fenestrated capillary" ;
rdfs:comment "Capillary that has pores in the endothelial cells (60-80 nm in diameter) that are spanned by a diaphragm of radially oriented fibrils and allow small molecules and limited amounts of protein to diffuse." ;
rdfs:subClassOf obo:UBERON_0001982 , obo:UBERON_0004638 .
obo:CHEBI_43968 a rdfs:Class ;
rdfs:label "meropenem" ;
rdfs:comment "A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively." ;
rdfs:subClassOf obo:CHEBI_16385 , obo:CHEBI_46634 , obo:CHEBI_46770 , obo:CHEBI_79020 .
obo:UBERON_0001071 a rdfs:Class ;
rdfs:label "superficial cervical artery" ;
rdfs:comment "It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery." ;
rdfs:subClassOf obo:UBERON_0012320 .
obo:CHEBI_76731 a rdfs:Class ;
rdfs:label "EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor" ;
rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*)." ;
rdfs:subClassOf obo:CHEBI_76725 .
obo:CL_0000515 a rdfs:Class ;
rdfs:label "skeletal muscle myoblast" ;
rdfs:comment "A myoblast that differentiates into skeletal muscle fibers." ;
rdfs:subClassOf obo:CL_0000056 .
obo:UBERON_0003497 a rdfs:Class ;
rdfs:label "abdomen blood vessel" ;
rdfs:comment "A blood vessel that is part of an abdomen [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003835 .
obo:PHIPO_0000316 a rdfs:Class ;
rdfs:label "obsolete decreased effector of virulence activation of host defense" ;
rdfs:comment "The pathogen effector entity has a decreased ability to activate host defense." .
obo:UBERON_0004141 a rdfs:Class ;
rdfs:label "heart tube" ;
rdfs:comment "An epithelial tube that will give rise to the mature heart." ;
rdfs:subClassOf obo:UBERON_0003914 , obo:UBERON_0005291 , obo:UBERON_0012275 .
obo:UBERON_0003472 a rdfs:Class ;
rdfs:label "cerebellar artery" ;
rdfs:comment "An artery that supplies blood to the cerebellum." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0003496 .
obo:GO_0032288 a rdfs:Class ;
rdfs:label "myelin assembly" ;
rdfs:comment "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system." ;
rdfs:subClassOf obo:GO_0010927 , obo:GO_0022607 .
obo:UBERON_0004668 a rdfs:Class ;
rdfs:label "fourth ventricle aperture" ;
rdfs:comment "One of: the 4th ventricle median or lateral apertures." ;
rdfs:subClassOf obo:UBERON_0000161 .
obo:CL_4307050 a rdfs:Class ;
rdfs:label "Astro-TE NN_5 Adamts18 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Adamts18 (Mmus), Crym (Mmus). It is distinguished from other Astro-TE NN_5 cells by expression of Adamts18. These cells are located in the Lateral septal complex, Striatum dorsal region, brain , in or close to the regions: Nucleus accumbens, Caudoputamen, lateral ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5230 Astro-TE NN_5." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301595 .
obo:CHEBI_50750 a rdfs:Class ;
rdfs:label "EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor" ;
rdfs:comment "A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands." ;
rdfs:subClassOf obo:CHEBI_70727 .
obo:CHEBI_27933 a rdfs:Class ;
rdfs:label "beta-lactam antibiotic" ;
rdfs:comment "An organonitrogen heterocyclic antibiotic that contains a β-lactam ring." ;
rdfs:subClassOf obo:CHEBI_25558 , obo:CHEBI_35627 .
obo:UBERON_0001731 a rdfs:Class ;
rdfs:label "cavity of pharynx" ;
rdfs:comment "An anatomical space that is enclosed by a pharynx." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0050432 a rdfs:Class ;
rdfs:label "catecholamine secretion" ;
rdfs:comment "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ;
rdfs:subClassOf obo:GO_0015850 , obo:GO_0032940 , obo:GO_0046903 , obo:GO_0071705 .
obo:GO_0098858 a rdfs:Class ;
rdfs:label "actin-based cell projection" ;
rdfs:comment "A cell projection supported by an assembly of actin filaments, and which lacks microtubules." ;
rdfs:subClassOf obo:GO_0120025 .
obo:CHEBI_76932 a rdfs:Class ;
rdfs:label "pathway inhibitor" ;
rdfs:comment "An enzyme inhibitor that interferes with one or more steps in a metabolic pathway." ;
rdfs:subClassOf obo:CHEBI_23924 .
obo:GO_0003220 a rdfs:Class ;
rdfs:label "left ventricular cardiac muscle tissue morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0055010 .
obo:GO_0000960 a rdfs:Class ;
rdfs:label "regulation of mitochondrial RNA catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0051252 , obo:GO_0065007 .
obo:GO_0002263 a rdfs:Class ;
rdfs:label "cell activation involved in immune response" ;
rdfs:comment "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0002252 .
obo:UBERON_0000947 a rdfs:Class ;
rdfs:label "aorta" ;
rdfs:comment "The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation." ;
rdfs:subClassOf obo:UBERON_0003509 , obo:UBERON_0003519 , obo:UBERON_0013768 .
obo:UBERON_0005688 a rdfs:Class ;
rdfs:label "lens vesicle cavity" ;
rdfs:comment "An anatomical cavity that is part of a lens vesicle." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:CHEBI_33535 a rdfs:Class ;
rdfs:label "sulfur hydride" ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_36902 .
obo:GO_0048713 a rdfs:Class ;
rdfs:label "regulation of oligodendrocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation." ;
rdfs:subClassOf obo:GO_0045685 , obo:GO_0065007 .
obo:UBERON_0016888 a rdfs:Class ;
rdfs:label "transitional anatomical structure" ;
rdfs:comment "An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development." ;
rdfs:subClassOf obo:UBERON_0005423 .
obo:PHIPO_0001119 a rdfs:Class ;
rdfs:label "abnormal protein phosphorylation"@en ;
rdfs:comment "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal." ;
rdfs:subClassOf obo:PHIPO_0001118 .
obo:CL_1001567 a rdfs:Class ;
rdfs:label "lung endothelial cell" ;
rdfs:comment "Any endothelial cell of vascular tree that is part of some lung." ;
rdfs:subClassOf obo:CL_0002139 .
obo:UBERON_0002363 a rdfs:Class ;
rdfs:label "dura mater" ;
rdfs:comment "Thick, fibrous meningeal covering surrounding the brain and spinal cord. It is the outermost of the three meningeal coverings. It consists of two layers: the periosteal dura linking the inner surface of the skull and the meningeal dura that lies above the arachnoid dural membrane. The meningeal layer draws away from the periosteal layer and certain locations to form the dural reflections." ;
rdfs:subClassOf obo:UBERON_0002360 .
obo:CHEBI_33287 a rdfs:Class ;
rdfs:label "fertilizer" ;
rdfs:comment "A fertilizer is any substance that is added to soil or water to assist the growth of plants." ;
rdfs:subClassOf obo:CHEBI_33286 .
obo:PHIPO_0000391 a rdfs:Class ;
rdfs:label "sensitive to carbendazim"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to carbendazim. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0011566 a rdfs:Class ;
rdfs:label "lumen of esophagus" ;
rdfs:comment "An anatomical cavity that is part of a esophagus." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0030936 a rdfs:Class ;
rdfs:label "transmembrane collagen trimer" ;
rdfs:comment "Any collagen trimer that passes through a lipid bilayer membrane." ;
rdfs:subClassOf obo:GO_0005581 , obo:GO_0098797 .
obo:NCBITaxon_1 a rdfs:Class ;
rdfs:label "root" ;
rdfs:subClassOf obo:COB_0000022 , obo:OBI_0100026 .
obo:CHEBI_59650 a rdfs:Class ;
rdfs:label "amino fatty acid" ;
rdfs:comment "A fatty acid containing at least one amino substituent." ;
rdfs:subClassOf obo:CHEBI_32952 , obo:CHEBI_33709 , obo:CHEBI_60690 .
obo:GO_0046545 a rdfs:Class ;
rdfs:label "development of primary female sexual characteristics" ;
rdfs:comment "The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion." ;
rdfs:subClassOf obo:GO_0045137 .
obo:CL_0009000 a rdfs:Class ;
rdfs:label "sensory neuron of spinal nerve" ;
rdfs:comment "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord." ;
rdfs:subClassOf obo:CL_0000101 , obo:CL_3000004 .
obo:UBERON_0007213 a rdfs:Class ;
rdfs:label "mesenchyme derived from head neural crest" ;
rdfs:comment "Mesenchyme that develops_from a cranial neural crest." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005253 .
obo:PHIPO_0001159 a rdfs:Class ;
rdfs:label "pathogen tissue to tissue migration within host phenotype"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype which affects the directional tissue to tissue movement of the pathogen within the host organism (GO:0044001)." ;
rdfs:subClassOf obo:PHIPO_0000332 .
obo:UBERON_0002536 a rdfs:Class ;
rdfs:label "arthropod sensillum" ;
rdfs:comment "Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt]." ;
rdfs:subClassOf obo:UBERON_0000020 .
obo:UBERON_0001985 a rdfs:Class ;
rdfs:label "corneal endothelium" ;
rdfs:comment "A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0010313 , obo:UBERON_0010371 , obo:UBERON_0015808 .
obo:GO_0007162 a rdfs:Class ;
rdfs:label "negative regulation of cell adhesion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." ;
rdfs:subClassOf obo:GO_0030155 , obo:GO_0048523 , obo:GO_0065007 .
obo:CHEBI_8489 a rdfs:Class ;
rdfs:label "propiconazole" ;
rdfs:comment "The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds." ;
rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_59779 , obo:CHEBI_87067 , obo:CHEBI_87100 .
obo:UBERON_0003604 a rdfs:Class ;
rdfs:label "trachea cartilage" ;
rdfs:comment "The ring-shaped cartilaginous structures that support the trachea." ;
rdfs:subClassOf obo:UBERON_0003603 , obo:UBERON_0007844 .
obo:GO_0010667 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle cell apoptotic process" ;
rdfs:comment "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." ;
rdfs:subClassOf obo:GO_0010664 , obo:GO_0010665 , obo:GO_0065007 .
obo:UBERON_0000456 a rdfs:Class ;
rdfs:label "secretion of exocrine gland" ;
rdfs:comment "A portion of organism substance that is produced by exocrine glands." ;
rdfs:subClassOf obo:UBERON_0000463 .
obo:UBERON_0004644 a rdfs:Class ;
rdfs:label "fourth ventricle ependyma" ;
rdfs:comment "An ependyma that is part of a fourth ventricle [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0004670 , obo:UBERON_0005357 .
obo:GO_0086027 a rdfs:Class ;
rdfs:label "AV node cell to bundle of His cell signaling" ;
rdfs:comment "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte." ;
rdfs:subClassOf obo:GO_0086067 .
obo:PHIPO_0000010 a rdfs:Class ;
rdfs:label "loss of pathogenicity" ;
rdfs:comment "A phenotype where the ability of a pathogen, to produce an infectious disease in another organism is abolished (pathogenicity was present and is now absent)." ;
rdfs:subClassOf obo:PHIPO_0000006 .
obo:PHIPO_0001058 a rdfs:Class ;
rdfs:label "normal rugose unicellular colony shape"@en ;
rdfs:comment "A single species phenotype where the shape of a colony of unicellular individuals is as rugose (wrinkled; corrugated) as normal (indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001057 .
obo:CHEBI_39173 a rdfs:Class ;
rdfs:label "chloropyridine" ;
rdfs:comment "Compounds containing a pyridine nucleus substituted with one or more chlorine atoms." ;
rdfs:subClassOf obo:CHEBI_26421 , obo:CHEBI_36683 .
a rdfs:Class ;
rdfs:label "CHGA" ;
rdfs:subClassOf obo:SO_0000704 .
obo:GO_2000669 a rdfs:Class ;
rdfs:label "negative regulation of dendritic cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000107 , obo:GO_2000668 .
obo:GO_0014037 a rdfs:Class ;
rdfs:label "Schwann cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function." ;
rdfs:subClassOf obo:GO_0010001 , obo:GO_0030154 .
obo:GO_0099547 a rdfs:Class ;
rdfs:label "regulation of translation at synapse, modulating synaptic transmission" ;
rdfs:comment "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." ;
rdfs:subClassOf obo:GO_0050804 , obo:GO_0065007 , obo:GO_0140243 .
obo:PR_000001945 a rdfs:Class ;
rdfs:label "transferrin receptor protein 1" ;
rdfs:comment "A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0060979 a rdfs:Class ;
rdfs:label "vasculogenesis involved in coronary vascular morphogenesis" ;
rdfs:comment "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes." ;
rdfs:subClassOf obo:GO_0001570 .
obo:PATO_0000001 a rdfs:Class ;
rdfs:label "quality" ;
rdfs:comment "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" ;
rdfs:subClassOf obo:BFO_0000020 .
obo:PHIPO_0001418 a rdfs:Class ;
rdfs:label "sensitive to penflufen" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to penflufen. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0030667 a rdfs:Class ;
rdfs:label "secretory granule membrane" ;
rdfs:comment "The lipid bilayer surrounding a secretory granule." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0030659 , obo:GO_0098588 .
obo:PHIPO_0001440 a rdfs:Class ;
rdfs:label "increased number of nuclei in asexual spore"@en ;
rdfs:comment "A single species phenotype where the frequency of occurrence of nuclei within an asexual spore is increased." ;
rdfs:subClassOf obo:PHIPO_0000127 .
obo:UBERON_0004872 a rdfs:Class ;
rdfs:label "splanchnic layer of lateral plate mesoderm" ;
rdfs:comment "Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0070664 a rdfs:Class ;
rdfs:label "negative regulation of leukocyte proliferation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0065007 , obo:GO_0070663 .
obo:PHIPO_0000050 a rdfs:Class ;
rdfs:label "decreased number of sexual spores"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of sexual spores is decreased." ;
rdfs:subClassOf obo:PHIPO_0000073 .
obo:CHEBI_36962 a rdfs:Class ;
rdfs:label "organochalcogen compound" ;
rdfs:comment "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_33304 .
obo:PR_000007479 a rdfs:Class ;
rdfs:label "fibroblast growth factor 1" ;
rdfs:comment "A protein that is a translation product of the human FGF1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_4520 a rdfs:Class ;
rdfs:label "diethofencarb" ;
rdfs:comment "A carbamate ester that is the isopropyl ester of (3,4-diethoxyphenyl)carbamic acid. A fungicide with strong activity against Botrytis cinerea and benzimidazole-resistant strains of Botryis spp." ;
rdfs:subClassOf obo:CHEBI_35618 , obo:CHEBI_87066 .
obo:PHIPO_0000815 a rdfs:Class ;
rdfs:label "sensitive to penicillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to penicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0042130 a rdfs:Class ;
rdfs:label "negative regulation of T cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of T cell proliferation." ;
rdfs:subClassOf obo:GO_0042129 , obo:GO_0050672 , obo:GO_0050868 , obo:GO_0065007 .
obo:GO_0021705 a rdfs:Class ;
rdfs:label "locus ceruleus formation" ;
rdfs:comment "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CHEBI_51270 a rdfs:Class ;
rdfs:label "tetracenes" ;
rdfs:comment "Compounds containing a tetracene skeleton." ;
rdfs:subClassOf obo:CHEBI_51269 .
obo:CHEBI_51811 a rdfs:Class ;
rdfs:label "ticarcillin(2-)" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:UBERON_0006207 a rdfs:Class ;
rdfs:label "aortico-pulmonary spiral septum" ;
rdfs:comment "The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development. The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from contractile, hemodynamic, and extracellular matrix interactions." ;
rdfs:subClassOf obo:UBERON_0002099 , obo:UBERON_0004142 .
obo:UBERON_0034714 a rdfs:Class ;
rdfs:label "epiphyseal tract" ;
rdfs:comment "A cranial nerve fiber tract that innervates the parietal eye." ;
rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0034713 .
obo:PHIPO_0001312 a rdfs:Class ;
rdfs:label "normal growth on zoxamide"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to zoxamide (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0051240 a rdfs:Class ;
rdfs:label "positive regulation of multicellular organismal process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ;
rdfs:subClassOf obo:GO_0048518 , obo:GO_0051239 , obo:GO_0065007 .
obo:UBERON_0004297 a rdfs:Class ;
rdfs:label "respiratory system blood vessel smooth muscle" ;
rdfs:comment "A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004225 , obo:UBERON_0004237 .
obo:CL_4307103 a rdfs:Class ;
rdfs:label "MFOL NN_3 Il23a myelin-forming oligodendrocyte (Mmus)" ;
rdfs:comment "A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Ppp1r14a (Mmus), Mroh3 (Mmus). It is distinguished from other MFOL NN_3 cells by expression of Il23a, Ppp1r14a. These cells are located in the Midbrain, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5283 MFOL NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301613 .
obo:PHIPO_0000305 a rdfs:Class ;
rdfs:label "obsolete effector of pathogenicity phenotype" ;
rdfs:comment "(Required for successful infection of the host species). The ability of an organism to activate or suppress host defenses to enable infectious disease. (Irrespective of the host genotype)." .
obo:GO_0032057 a rdfs:Class ;
rdfs:label "negative regulation of translational initiation in response to stress" ;
rdfs:comment "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0045947 , obo:GO_0065007 .
obo:GO_0048486 a rdfs:Class ;
rdfs:label "parasympathetic nervous system development" ;
rdfs:comment "The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:CHEBI_39146 a rdfs:Class ;
rdfs:label "trichostatin" ;
rdfs:subClassOf obo:CHEBI_49319 .
obo:PATO_0000136 a rdfs:Class ;
rdfs:label "closure" ;
rdfs:comment "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:GO_0048708 a rdfs:Class ;
rdfs:label "astrocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function." ;
rdfs:subClassOf obo:GO_0010001 , obo:GO_0030154 .
obo:GO_0022412 a rdfs:Class ;
rdfs:label "cellular process involved in reproduction in multicellular organism" ;
rdfs:comment "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0048609 .
obo:PHIPO_0000367 a rdfs:Class ;
rdfs:label "premature pathogen growth within host"@en ;
rdfs:comment "A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host begins sooner than normal." ;
rdfs:subClassOf obo:PHIPO_0000954 .
obo:CHEBI_33836 a rdfs:Class ;
rdfs:label "benzenoid aromatic compound" ;
rdfs:subClassOf obo:CHEBI_33598 , obo:CHEBI_33659 .
obo:GO_1905315 a rdfs:Class ;
rdfs:label "cell proliferation involved in endocardial cushion morphogenesis" ;
rdfs:comment "Any cell proliferation that is involved in endocardial cushion morphogenesis." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0061323 .
obo:CL_0008061 a rdfs:Class ;
rdfs:label "GABA-Chol neuron" ;
rdfs:comment "A neuron that releases both gamma-aminobutyric acid and acetylcholine as vesicular neurotransmitters. Examples include some types of striatal interneuron." ;
rdfs:subClassOf obo:CL_0000108 , obo:CL_0000540 , obo:CL_0000617 .
obo:UBERON_0001804 a rdfs:Class ;
rdfs:label "capsule of lens" ;
rdfs:comment "The elastic, clear, membrane-like structure, that is outer most layer of the lens." ;
rdfs:subClassOf obo:UBERON_0000476 , obo:UBERON_0005764 .
obo:CL_4310088 a rdfs:Class ;
rdfs:label "BF SKOR1 Glut glutamatergic neuron of the basal ganglia (Primate)" ;
rdfs:comment "A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:BF SKOR1 Glut." ;
rdfs:subClassOf obo:CL_0000700 , obo:CL_4042040 .
obo:CHEBI_133833 a rdfs:Class ;
rdfs:label "benznidazole" ;
rdfs:comment "A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitroimidazol-1-yl)acetic acid with the aromatic amino group of benzylamine. Used for treatment of Chagas disease." ;
rdfs:subClassOf obo:CHEBI_24780 , obo:CHEBI_29347 , obo:CHEBI_35716 .
obo:CHEBI_25555 a rdfs:Class ;
rdfs:label "nitrogen atom" ;
rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33300 .
obo:GO_1905155 a rdfs:Class ;
rdfs:label "positive regulation of membrane invagination" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of membrane invagination." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1905153 .
obo:CHEBI_33672 a rdfs:Class ;
rdfs:label "heterobicyclic compound" ;
rdfs:comment "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." ;
rdfs:subClassOf obo:CHEBI_33636 , obo:CHEBI_5686 .
obo:CL_1000457 a rdfs:Class ;
rdfs:label "mesothelial cell of visceral peritoneum" ;
rdfs:comment "A mesothelial cell that is part of the visceral peritoneum." ;
rdfs:subClassOf obo:CL_0000077 , obo:CL_1000490 .
obo:UBERON_0006670 a rdfs:Class ;
rdfs:label "central tendon of diaphragm" ;
rdfs:comment "The three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers." ;
rdfs:subClassOf obo:UBERON_0000043 , obo:UBERON_0003570 , obo:UBERON_0003837 .
obo:CL_0000147 a rdfs:Class ;
rdfs:label "pigment cell" ;
rdfs:comment "A pigment cell is a cell that contains pigment granules." ;
rdfs:subClassOf obo:CL_0000325 .
obo:GO_0034629 a rdfs:Class .
obo:GO_0061971 a rdfs:Class ;
rdfs:label "replacement bone morphogenesis" ;
rdfs:comment "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone." ;
rdfs:subClassOf obo:GO_0060349 .
obo:PATO_0070010 a rdfs:Class ;
rdfs:label "stellate morphology" ;
rdfs:comment "A cell morphology that inheres in neurons that have dendritic processes radiating from the cell body forming a star-like shape." ;
rdfs:subClassOf obo:PATO_0070026 .
obo:GO_0071874 a rdfs:Class ;
rdfs:label "cellular response to norepinephrine stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_0071870 , obo:GO_0071873 .
obo:PHIPO_0000769 a rdfs:Class ;
rdfs:label "sensitive to gatifloxacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to gatifloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0071692 a rdfs:Class ;
rdfs:label "protein localization to extracellular region" ;
rdfs:comment "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033036 .
obo:CHEBI_39456 a rdfs:Class ;
rdfs:label "antiglaucoma drug" ;
rdfs:comment "Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye." ;
rdfs:subClassOf obo:CHEBI_66981 .
obo:GO_0009101 a rdfs:Class ;
rdfs:label "glycoprotein biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0009059 , obo:GO_0009100 , obo:GO_1901137 .
obo:CHEBI_84002 a rdfs:Class ;
rdfs:label "1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one" ;
rdfs:comment "A member of the class of triazoles that is 1-hydroxy-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one in which the hydroxyl hydrogen is replaced by a 4-chlorophenyl group." ;
rdfs:subClassOf obo:CHEBI_141498 , obo:CHEBI_17087 , obo:CHEBI_35618 , obo:CHEBI_35727 , obo:CHEBI_83403 .
obo:CHEBI_46077 a rdfs:Class ;
rdfs:label "4H-1,2,4-triazole" ;
rdfs:subClassOf obo:CHEBI_35560 .
obo:GO_1903779 a rdfs:Class ;
rdfs:label "regulation of cardiac conduction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiac conduction." ;
rdfs:subClassOf obo:GO_0008016 , obo:GO_0065007 .
obo:PR_000013246 a rdfs:Class ;
rdfs:label "prolactin" ;
rdfs:comment "A somatotropin hormone family member that is a translation product of the human PRL gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000029968 .
obo:GO_0045296 a rdfs:Class ;
rdfs:label "cadherin binding" ;
rdfs:comment "Binding to cadherin, a type I membrane protein involved in cell adhesion." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0050839 .
obo:GO_0019825 a rdfs:Class ;
rdfs:label "oxygen binding" ;
rdfs:comment "Binding to oxygen (O2)." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0036094 .
obo:GO_0046907 a rdfs:Class ;
rdfs:label "intracellular transport" ;
rdfs:comment "The directed movement of substances within a cell." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0051641 , obo:GO_0051649 .
obo:CL_4307055 a rdfs:Class ;
rdfs:label "Astro-OLF NN_3 Ecrg4 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C230072F16Rik (Mmus), Dipk1c (Mmus), Ecrg4 (Mmus). It is distinguished from other Astro-OLF NN_3 cells by expression of Ecrg4. These cells are located in the Olfactory areas , in or close to the regions: Main olfactory bulb, granule layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5235 Astro-OLF NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301598 .
obo:GO_0140572 a rdfs:Class ;
rdfs:label "vacuole fission" ;
rdfs:comment "The division of a vacuole within a cell to form two or more separate vacuoles." ;
rdfs:subClassOf obo:GO_0048285 .
obo:CHEBI_50471 a rdfs:Class ;
rdfs:label "primary arylamine" ;
rdfs:comment "A primary amine formally derived from ammonia by replacing one hydrogen atom by an aryl group. R-NH2 where R is an aryl group." ;
rdfs:subClassOf obo:CHEBI_32877 , obo:CHEBI_33860 .
obo:GO_0009890 a rdfs:Class ;
rdfs:label "negative regulation of biosynthetic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0009892 , obo:GO_0065007 .
obo:CHEBI_22563 a rdfs:Class ;
rdfs:label "anion" ;
rdfs:comment "A monoatomic or polyatomic species having one or more elementary charges of the electron." ;
rdfs:subClassOf obo:CHEBI_24870 .
obo:PHIPO_0000358 a rdfs:Class ;
rdfs:label "obsolete non-functional pathogen penetration structure in contact with host" ;
rdfs:comment "A pathogen growth with host phenotype in which the pathogen forms a non-functional specialized penetration structure." .
obo:CHEBI_81781 a rdfs:Class ;
rdfs:label "tebuconazole" ;
rdfs:comment "A racemate composed of equimolar amounts of (R)- and (S)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87067 , obo:CHEBI_87100 .
obo:GO_0046620 a rdfs:Class ;
rdfs:label "regulation of organ growth" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." ;
rdfs:subClassOf obo:GO_0048638 , obo:GO_0051239 , obo:GO_0065007 .
obo:GO_0030574 a rdfs:Class ;
rdfs:label "collagen catabolic process" ;
rdfs:comment "The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0032963 .
obo:CL_0002605 a rdfs:Class ;
rdfs:label "astrocyte of the cerebral cortex" ;
rdfs:comment "A transcriptomically distinct astrocyte that is found in the cerebral cortex." ;
rdfs:subClassOf obo:CL_0000127 , obo:CL_0012000 , obo:CL_1001579 .
obo:GO_0085029 a rdfs:Class ;
rdfs:label "extracellular matrix assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of the extracellular matrix." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0030198 .
obo:GO_1905903 a rdfs:Class ;
rdfs:label "negative regulation of mesoderm formation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905902 , obo:GO_2000381 .
obo:CHEBI_9937 a rdfs:Class .
obo:GO_0003073 a rdfs:Class ;
rdfs:label "regulation of systemic arterial blood pressure" ;
rdfs:comment "The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure." ;
rdfs:subClassOf obo:GO_0008217 .
obo:CHEBI_26004 a rdfs:Class ;
rdfs:label "phenylpropanoid" ;
rdfs:comment "Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin." ;
rdfs:subClassOf obo:CHEBI_33659 .
obo:PHIPO_0000396 a rdfs:Class ;
rdfs:label "sensitive to azoxystrobin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to azoxystrobin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000804 .
obo:GO_0031117 a rdfs:Class ;
rdfs:label "positive regulation of microtubule depolymerization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." ;
rdfs:subClassOf obo:GO_0031112 , obo:GO_0031114 , obo:GO_0065007 , obo:GO_1901881 , obo:GO_1902905 .
obo:GO_2000242 a rdfs:Class ;
rdfs:label "negative regulation of reproductive process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0065007 , obo:GO_2000241 .
obo:GO_0061650 a rdfs:Class ;
rdfs:label "ubiquitin-like protein conjugating enzyme activity" ;
rdfs:comment "Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another molecule, usually another protein, via the reaction X-SCP + Y = Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue." ;
rdfs:subClassOf obo:GO_0019787 .
obo:GO_1903980 a rdfs:Class ;
rdfs:label "positive regulation of microglial cell activation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of microglial cell activation." ;
rdfs:subClassOf obo:GO_0043032 , obo:GO_0065007 , obo:GO_0150078 , obo:GO_1903978 .
obo:GO_0002833 a rdfs:Class ;
rdfs:label "positive regulation of response to biotic stimulus" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." ;
rdfs:subClassOf obo:GO_0002831 , obo:GO_0048584 , obo:GO_0065007 .
obo:PHIPO_0000950 a rdfs:Class ;
rdfs:label "obsolete pathogen spore germination on host phenotype" ;
rdfs:comment "Note: to add asexual/sexual etc" .
obo:GO_0071169 a rdfs:Class ;
rdfs:label "establishment of protein localization to chromatin" ;
rdfs:comment "The directed movement of a protein to a part of a chromosome that is organized into chromatin." ;
rdfs:subClassOf obo:GO_0045184 , obo:GO_0070199 , obo:GO_0071168 .
obo:GO_0032590 a rdfs:Class ;
rdfs:label "dendrite membrane" ;
rdfs:comment "The portion of the plasma membrane surrounding a dendrite." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0032589 .
obo:UBERON_0001178 a rdfs:Class ;
rdfs:label "visceral peritoneum" ;
rdfs:comment "The inner layer of peritoneum that is wrapped around organs located inside the intraperitoneal space." ;
rdfs:subClassOf obo:UBERON_0022350 .
obo:CHEBI_46850 a rdfs:Class ;
rdfs:label "organoammonium salt" ;
rdfs:subClassOf obo:CHEBI_35276 .
obo:GO_1903539 a rdfs:Class ;
rdfs:label "protein localization to postsynaptic membrane" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0062237 , obo:GO_0072657 , obo:GO_1990778 .
obo:UBERON_0002458 a rdfs:Class ;
rdfs:label "spinal artery" ;
rdfs:comment "Arteries that supply the spinal cord." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0004573 .
obo:PR_000001785 a rdfs:Class ;
rdfs:label "prominin" ;
rdfs:comment "A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0097104 a rdfs:Class ;
rdfs:label "postsynaptic membrane assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft)." ;
rdfs:subClassOf obo:GO_0001941 , obo:GO_0009987 , obo:GO_0071709 .
obo:GO_0009416 a rdfs:Class ;
rdfs:label "response to light stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." ;
rdfs:subClassOf obo:GO_0009314 , obo:GO_0050896 .
obo:CHEBI_38503 a rdfs:Class ;
rdfs:label "EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor" ;
rdfs:comment "A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H+-translocating), EC 1.6.5.3." ;
rdfs:subClassOf obo:CHEBI_38497 , obo:CHEBI_76866 .
obo:GO_0060501 a rdfs:Class ;
rdfs:label "positive regulation of epithelial cell proliferation involved in lung morphogenesis" ;
rdfs:comment "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape." ;
rdfs:subClassOf obo:GO_0050679 , obo:GO_0065007 , obo:GO_2000794 .
obo:GO_0150102 a rdfs:Class ;
rdfs:label "negative regulation of monocyte activation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation." ;
rdfs:subClassOf obo:GO_0002695 , obo:GO_0065007 .
obo:CHEBI_29103 a rdfs:Class ;
rdfs:label "potassium(1+)" ;
rdfs:comment "A monoatomic monocation obtained from potassium." ;
rdfs:subClassOf obo:CHEBI_25414 , obo:CHEBI_33504 , obo:CHEBI_37247 , obo:CHEBI_60242 .
obo:UBERON_0008229 a rdfs:Class ;
rdfs:label "craniocervical region musculature" ;
rdfs:comment "Musculature system of the pharyngeal and head regions." ;
rdfs:subClassOf obo:UBERON_0001015 .
obo:GO_2000107 a rdfs:Class ;
rdfs:label "negative regulation of leukocyte apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process." ;
rdfs:subClassOf obo:GO_0043066 , obo:GO_0065007 , obo:GO_2000106 .
obo:GO_0006022 a rdfs:Class ;
rdfs:label "aminoglycan metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0043170 , obo:GO_1901135 .
obo:PHIPO_0000602 a rdfs:Class ;
rdfs:label "resistance to ethionamide"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ethionamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000809 a rdfs:Class ;
rdfs:label "sensitive to florfenicol"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to florfenicol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0050767 a rdfs:Class ;
rdfs:label "regulation of neurogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." ;
rdfs:subClassOf obo:GO_0051960 , obo:GO_0060284 , obo:GO_0065007 .
obo:UBERON_0005282 a rdfs:Class ;
rdfs:label "ventricular system of brain" ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:PHIPO_0000477 a rdfs:Class ;
rdfs:label "presence of pathogen necrotrophic effector-mediated host programmed cell death"@en ;
rdfs:comment "A phenotype where the process of a necrotrophic pathogen effector activating the host immune system to trigger programmed cell death is present." ;
rdfs:subClassOf obo:PHIPO_0000280 , obo:PHIPO_0000480 .
obo:UBERON_0004857 a rdfs:Class ;
rdfs:label "skeletal muscle connective tissue" ;
rdfs:comment "A connective tissue that surrounds a skeletal muscle tissue." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:UBERON_0002168 a rdfs:Class ;
rdfs:label "left lung" ;
rdfs:comment "Lung which consists of the left upper lobe and left lower lobe.[FMA]." ;
rdfs:subClassOf obo:UBERON_0002048 .
obo:UBERON_0006761 a rdfs:Class ;
rdfs:label "corneo-scleral junction" ;
rdfs:comment "The edge of the cornea where it joins the sclera; the limbus is a common site for the occurrence of corneal epithelial neoplasm." ;
rdfs:subClassOf obo:UBERON_0007651 .
obo:PHIPO_0001328 a rdfs:Class ;
rdfs:label "normal growth on myclobutanil"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to myclobutanil (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0048660 a rdfs:Class ;
rdfs:label "regulation of smooth muscle cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:GO_0043171 a rdfs:Class ;
rdfs:label "peptide catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." ;
rdfs:subClassOf obo:GO_0006518 , obo:GO_0009056 .
obo:CHEBI_25944 a rdfs:Class ;
rdfs:label "pesticide" ;
rdfs:comment "Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_0030448 a rdfs:Class ;
rdfs:label "hyphal growth" ;
rdfs:comment "Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls." ;
rdfs:subClassOf obo:GO_0030447 .
obo:CL_0002613 a rdfs:Class ;
rdfs:label "striatum neuron" ;
rdfs:comment "A neuron of the striatum." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_0012001 .
obo:GO_0099145 a rdfs:Class ;
rdfs:label "regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane." ;
rdfs:subClassOf obo:GO_0017157 , obo:GO_0051223 , obo:GO_0065007 , obo:GO_0065008 , obo:GO_1902683 , obo:GO_1904375 , obo:GO_1905475 .
obo:UBERON_0008907 a rdfs:Class ;
rdfs:label "dermal bone" ;
rdfs:comment "Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0004756 , obo:UBERON_0007842 .
obo:GO_0086067 a rdfs:Class ;
rdfs:label "AV node cell to bundle of His cell communication" ;
rdfs:comment "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0086065 .
obo:PHIPO_0000337 a rdfs:Class ;
rdfs:label "obsolete extracellular growth phenotype" .
obo:GO_0060231 a rdfs:Class ;
rdfs:label "mesenchymal to epithelial transition" ;
rdfs:comment "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030855 .
obo:UBERON_0034713 a rdfs:Class ;
rdfs:label "cranial neuron projection bundle" ;
rdfs:comment "Any of the cranial nerves, or their central nervous system analogs (the optic tract, the epiphyseal tract). These analogs are not true nerves, and are instead evaginated sensory afferents emanating from the brain." ;
rdfs:subClassOf obo:UBERON_0000122 , obo:UBERON_0015212 .
obo:GO_0019093 a rdfs:Class ;
rdfs:label "mitochondrial RNA localization" ;
rdfs:comment "Any process in which mitochondrial RNA is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0006403 .
obo:UBERON_0019204 a rdfs:Class ;
rdfs:label "skin epithelium" ;
rdfs:comment "Any region of epithelium that is part of a skin region." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0060946 a rdfs:Class ;
rdfs:label "cardiac blood vessel endothelial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels." ;
rdfs:subClassOf obo:GO_0003348 , obo:GO_0030154 , obo:GO_0060837 .
obo:GO_0030072 a rdfs:Class ;
rdfs:label "peptide hormone secretion" ;
rdfs:comment "The regulated release of a peptide hormone from a cell." ;
rdfs:subClassOf obo:GO_0002790 , obo:GO_0046879 , obo:GO_0046903 .
obo:CHEBI_59644 a rdfs:Class ;
rdfs:label "oxo fatty acid" ;
rdfs:comment "Any fatty acid containing at least one aldehydic or ketonic group in addition to the carboxylic acid group." ;
rdfs:subClassOf obo:CHEBI_25754 , obo:CHEBI_35366 .
obo:GO_0031646 a rdfs:Class ;
rdfs:label "positive regulation of nervous system process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." ;
rdfs:subClassOf obo:GO_0031644 , obo:GO_0051240 , obo:GO_0065007 .
obo:CL_0002540 a rdfs:Class ;
rdfs:label "mesenchymal stem cell of the bone marrow" ;
rdfs:comment "A mesenchymal stem cell that is part of the bone marrow." ;
rdfs:subClassOf obo:CL_0000134 , obo:CL_0002092 .
obo:PHIPO_0000550 a rdfs:Class ;
rdfs:label "resistance to ampicillin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ampicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:CL_4307083 a rdfs:Class ;
rdfs:label "hypendemal cell (Mmus)" ;
rdfs:comment "A hypendymal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Sspo (Mmus), Wfdc2 (Mmus). It is distinguished from other Astro-Epen cells by expression of Sspo, Wfdc2. These cells are located in the Midbrain, brain , in or close to the regions: third ventricle, posterior commissure, Subcommissural organ . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5263 Hypendymal NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4023181 .
obo:UBERON_0004923 a rdfs:Class ;
rdfs:label "organ component layer" ;
rdfs:comment "A part of a wall of an organ that forms a layer." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:CHEBI_33661 a rdfs:Class ;
rdfs:label "monocyclic compound" ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:UBERON_0002345 a rdfs:Class ;
rdfs:label "descending thoracic aorta" ;
rdfs:comment "The part of the aorta that extends from the arch of the aorta to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest." ;
rdfs:subClassOf obo:UBERON_0013522 .
obo:CHEBI_76898 a rdfs:Class ;
rdfs:label "EC 1.14.14.1 (unspecific monooxygenase) inhibitor" ;
rdfs:comment "An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1)." ;
rdfs:subClassOf obo:CHEBI_76838 .
obo:UBERON_0003408 a rdfs:Class ;
rdfs:label "gland of digestive tract" ;
rdfs:comment "A gland that is part of a digestive tract [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002530 , obo:UBERON_0013765 .
obo:CHEBI_71392 a rdfs:Class ;
rdfs:label "tetracycline(1-)" ;
rdfs:comment "An organic anion that is the conjugate base of tetracycline zwitterion obtained by deprotonation of the two enolic hydroxy groups and protonation of the tertiary amino group." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:CL_4310109 a rdfs:Class ;
rdfs:label "SN-VTR CALB1 Dopa substantia nigra dopaminergic neuron (Primate)" ;
rdfs:comment "A substantia nigra dopaminergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR CALB1 Dopa." ;
rdfs:subClassOf obo:CL_4042025 .
obo:PHIPO_0000635 a rdfs:Class ;
rdfs:label "resistance to closantel"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to closantel. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0030902 a rdfs:Class ;
rdfs:label "hindbrain development" ;
rdfs:comment "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0031967 a rdfs:Class ;
rdfs:label "organelle envelope" ;
rdfs:comment "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0001751 a rdfs:Class ;
rdfs:label "compound eye photoreceptor cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell." ;
rdfs:subClassOf obo:GO_0001754 , obo:GO_0030154 .
obo:GO_0097402 a rdfs:Class ;
rdfs:label "neuroblast migration" ;
rdfs:comment "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron." ;
rdfs:subClassOf obo:GO_0016477 .
obo:GO_0061184 a rdfs:Class ;
rdfs:label "positive regulation of dermatome development" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." ;
rdfs:subClassOf obo:GO_0040019 , obo:GO_0061183 , obo:GO_0065007 .
obo:CL_0011012 a rdfs:Class ;
rdfs:label "neural crest cell" ;
rdfs:comment "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." ;
rdfs:subClassOf obo:CL_0000048 , obo:CL_0002321 .
obo:UBERON_0004236 a rdfs:Class ;
rdfs:label "arteriole smooth muscle" ;
rdfs:comment "A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004237 , obo:UBERON_0004695 .
obo:CHEBI_53658 a rdfs:Class ;
rdfs:label "ceftriaxone(1-)" ;
rdfs:comment "A cephalosporin carboxylis acid anion having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups, formed by proton loss from the carboxy group of ceftriaxone." ;
rdfs:subClassOf obo:CHEBI_52440 .
obo:NCBITaxon_9347 a rdfs:Class ;
rdfs:label "Eutheria" ;
rdfs:subClassOf obo:NCBITaxon_32525 .
obo:UBERON_0011272 a rdfs:Class ;
rdfs:label "embryonic skin basal layer" ;
rdfs:subClassOf obo:UBERON_0000490 .
obo:GO_0014053 a rdfs:Class ;
rdfs:label "negative regulation of gamma-aminobutyric acid secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." ;
rdfs:subClassOf obo:GO_0014052 , obo:GO_0032891 , obo:GO_0051048 , obo:GO_0051956 , obo:GO_0065007 .
obo:CL_4300028 a rdfs:Class ;
rdfs:label "cerebellar GABAergic neuron (Mmus)" ;
rdfs:comment "A cerebellar neuron of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:28 CB GABA." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000617 , obo:CL_1001611 .
obo:GO_0044090 a rdfs:Class ;
rdfs:label "positive regulation of vacuole organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0044088 , obo:GO_0065007 .
a rdfs:Class ;
rdfs:label "Nucleus raphe pontis" ;
rdfs:subClassOf , obo:UBERON_0002047 .
obo:CHEBI_83732 a rdfs:Class ;
rdfs:label "3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione" ;
rdfs:comment "A member of the class of oxazolidinones that is 5-ethenyl-5-methyl-2,4-oxazolidinedione in which the imide hydrogen is replaced by a 3,5-dichlorophenyl group." ;
rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_35356 , obo:CHEBI_55374 , obo:CHEBI_78840 .
obo:CHEBI_83291 a rdfs:Class ;
rdfs:label "1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine" ;
rdfs:comment "A member of the class of piperidines that is N-isobutylpiperidine in which a hydrogen of one of the methyl groups is replaced by a p-tert-butylphenyl group." ;
rdfs:subClassOf obo:CHEBI_26151 , obo:CHEBI_32876 .
obo:CHEBI_38218 a rdfs:Class ;
rdfs:label "isophthalonitrile" ;
rdfs:subClassOf obo:CHEBI_18379 .
obo:GO_0061148 a rdfs:Class ;
rdfs:label "extracellular matrix organization involved in endocardium development" ;
rdfs:comment "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ;
rdfs:subClassOf obo:GO_0030198 .
obo:GO_0003159 a rdfs:Class ;
rdfs:label "morphogenesis of an endothelium" ;
rdfs:comment "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." ;
rdfs:subClassOf obo:GO_0002009 , obo:GO_0009653 .
obo:GO_1905477 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to membrane" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to membrane." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903829 , obo:GO_1905475 .
obo:GO_0099003 a rdfs:Class ;
rdfs:label "vesicle-mediated transport in synapse" ;
rdfs:comment "Any vesicle-mediated transport that occurs in a synapse." ;
rdfs:subClassOf obo:GO_0016192 .
obo:CHEBI_29214 a rdfs:Class ;
rdfs:label "sulfonic acid" ;
rdfs:subClassOf obo:CHEBI_33402 .
obo:GO_1901715 a rdfs:Class ;
rdfs:label "regulation of GABA catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process." ;
rdfs:subClassOf obo:GO_0006521 , obo:GO_0009894 , obo:GO_0062012 , obo:GO_0065007 .
obo:GO_0002320 a rdfs:Class ;
rdfs:label "lymphoid progenitor cell differentiation" ;
rdfs:comment "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages." ;
rdfs:subClassOf obo:GO_0002244 , obo:GO_0030154 .
obo:GO_0045769 a rdfs:Class ;
rdfs:label "negative regulation of asymmetric cell division" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." ;
rdfs:subClassOf obo:GO_0009786 , obo:GO_0051782 , obo:GO_0065007 .
obo:CHEBI_77747 a rdfs:Class ;
rdfs:label "EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitor" ;
rdfs:comment "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of phospholipid-translocating ATPase (EC 3.6.3.1)." ;
rdfs:subClassOf obo:CHEBI_76895 .
obo:CHEBI_33246 a rdfs:Class ;
rdfs:label "inorganic group" ;
rdfs:comment "Any substituent group which does not contain carbon." ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:GO_0007589 a rdfs:Class ;
rdfs:label "body fluid secretion" ;
rdfs:comment "The controlled release of a fluid by a cell or tissue in an animal." ;
rdfs:subClassOf obo:GO_0046903 , obo:GO_0050878 .
obo:GO_0042073 a rdfs:Class ;
rdfs:label "intraciliary transport" ;
rdfs:comment "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0010970 , obo:GO_0031503 .
obo:UBERON_0004118 a rdfs:Class ;
rdfs:label "vasculature of iris" ;
rdfs:comment "A vasculature that is part of a iris [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0002203 .
obo:UBERON_0014399 a rdfs:Class ;
rdfs:label "sinusoidal space" ;
rdfs:comment "An anatomical space that is enclosed by a sinusoid." ;
rdfs:subClassOf obo:UBERON_0000464 , obo:UBERON_0010161 .
obo:GO_1990182 a rdfs:Class ;
rdfs:label "exosomal secretion" ;
rdfs:comment "The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." ;
rdfs:subClassOf obo:GO_0006887 , obo:GO_0051650 .
obo:GO_1905277 a rdfs:Class ;
rdfs:label "negative regulation of epithelial tube formation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation." ;
rdfs:subClassOf obo:GO_0051241 , obo:GO_0065007 , obo:GO_1905276 , obo:GO_1905331 .
obo:UBERON_0002315 a rdfs:Class ;
rdfs:label "gray matter of spinal cord" ;
rdfs:comment "The ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue." ;
rdfs:subClassOf obo:UBERON_0002020 .
obo:CHEBI_9448 a rdfs:Class ;
rdfs:label "terbinafine" ;
rdfs:comment "A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections." ;
rdfs:subClassOf obo:CHEBI_25477 , obo:CHEBI_32876 , obo:CHEBI_59831 , obo:CHEBI_87127 .
obo:UBERON_0003073 a rdfs:Class ;
rdfs:label "lens placode" ;
rdfs:comment "A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]." ;
rdfs:subClassOf obo:UBERON_0002546 , obo:UBERON_0005085 , obo:UBERON_0006598 , obo:UBERON_0011814 .
a rdfs:Class ;
rdfs:label "Cortical subplate" ;
rdfs:subClassOf , obo:UBERON_0004035 .
obo:UBERON_0000114 a rdfs:Class ;
rdfs:label "lung connective tissue" ;
rdfs:comment "The connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003580 , obo:UBERON_0003837 , obo:UBERON_0004120 .
obo:CHEBI_194135 a rdfs:Class ;
rdfs:label "9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid" ;
rdfs:comment "An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively." ;
rdfs:subClassOf obo:CHEBI_37143 , obo:CHEBI_46848 , obo:CHEBI_46920 , obo:CHEBI_47881 , obo:CHEBI_53665 .
obo:PHIPO_0000587 a rdfs:Class ;
rdfs:label "resistance to vinclozolin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to vinclozolin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000887 a rdfs:Class ;
rdfs:label "sensitive to ethambutol"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ethambutol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0021892 a rdfs:Class ;
rdfs:label "cerebral cortex GABAergic interneuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex." ;
rdfs:subClassOf obo:GO_0021895 , obo:GO_0030154 , obo:GO_0097154 .
obo:CHEBI_35681 a rdfs:Class ;
rdfs:label "secondary alcohol" ;
rdfs:comment "A secondary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:GO_0015187 a rdfs:Class ;
rdfs:label "glycine transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid." ;
rdfs:subClassOf obo:GO_0015175 , obo:GO_0022857 , obo:GO_0046943 .
obo:GO_0021954 a rdfs:Class ;
rdfs:label "central nervous system neuron development" ;
rdfs:comment "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." ;
rdfs:subClassOf obo:GO_0048468 , obo:GO_0048666 .
obo:UBERON_0003102 a rdfs:Class ;
rdfs:label "surface structure" ;
rdfs:comment "Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0045652 a rdfs:Class ;
rdfs:label "regulation of megakaryocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation." ;
rdfs:subClassOf obo:GO_0045637 , obo:GO_0065007 .
obo:GO_1903664 a rdfs:Class ;
rdfs:label "regulation of asexual reproduction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of asexual reproduction." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000241 .
obo:CHEBI_8273 a rdfs:Class ;
rdfs:label "plumbagin" ;
rdfs:comment "A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively." ;
rdfs:subClassOf obo:CHEBI_132157 , obo:CHEBI_33853 .
obo:GO_0043586 a rdfs:Class ;
rdfs:label "tongue development" ;
rdfs:comment "The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech." ;
rdfs:subClassOf obo:GO_0007423 , obo:GO_0048856 .
obo:GO_0040020 a rdfs:Class ;
rdfs:label "regulation of meiotic nuclear division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0051445 , obo:GO_0051783 , obo:GO_0065007 .
obo:CL_4307030 a rdfs:Class ;
rdfs:label "Astro-NT NN_1 Nuf2 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Sfrp5 (Mmus), Cldn10 (Mmus), Riiad1 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Nuf2, Shroom3. These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5210 Astro-NT NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301589 .
obo:GO_0120275 a rdfs:Class ;
rdfs:label "cerebral blood circulation" ;
rdfs:comment "The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products." ;
rdfs:subClassOf obo:GO_0008015 .
obo:CL_1001610 a rdfs:Class ;
rdfs:label "bone marrow hematopoietic cell" ;
rdfs:comment "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes." ;
rdfs:subClassOf obo:CL_0000988 , obo:CL_0002092 .
obo:GO_0070050 a rdfs:Class ;
rdfs:label "neuron cellular homeostasis" ;
rdfs:comment "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state." ;
rdfs:subClassOf obo:GO_0019725 .
obo:GO_0061194 a rdfs:Class ;
rdfs:label "taste bud morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0090596 .
obo:PHIPO_0000266 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction protein transport" ;
rdfs:comment "A pathogen host interaction (cellular process??) phenotype in which protein transport is abnormal." .
obo:PHIPO_0001199 a rdfs:Class ;
rdfs:label "disease absent"@en ;
rdfs:comment "A pathogen host interaction phenotype where disease is absent." ;
rdfs:subClassOf obo:PHIPO_0001198 .
obo:GO_0022031 a rdfs:Class ;
rdfs:label "telencephalon astrocyte cell migration" ;
rdfs:comment "The orderly movement of an astrocyte cell through the telencephalon." ;
rdfs:subClassOf obo:GO_0022030 , obo:GO_0043615 .
obo:CHEBI_22314 a rdfs:Class ;
rdfs:label "alkali metal atom" ;
rdfs:subClassOf obo:CHEBI_33318 , obo:CHEBI_33521 , obo:CHEBI_33559 .
obo:PHIPO_0000747 a rdfs:Class ;
rdfs:label "sensitive to brassinin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to brassinin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CL_0000691 a rdfs:Class ;
rdfs:label "stellate interneuron" ;
rdfs:comment "Any interneuron that has characteristic some stellate morphology." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_0000122 .
obo:PHIPO_0001239 a rdfs:Class ;
rdfs:label "pathogen inhibition of host defense induced alkalization"@en ;
rdfs:comment "A pathogen host interaction phenotype where the host induced pH increase in response to pathogen colonization is inhibited." ;
rdfs:subClassOf obo:PHIPO_0001108 .
obo:UBERON_0035818 a rdfs:Class ;
rdfs:label "visceral fat" ;
rdfs:comment "Any fat deposit surrounding a visceral organ." ;
rdfs:subClassOf obo:UBERON_0001013 .
obo:CHEBI_35868 a rdfs:Class ;
rdfs:label "hydroxy monocarboxylic acid" ;
rdfs:comment "Any monocarboxylic acid which also contains a separate (alcoholic or phenolic) hydroxy substituent." ;
rdfs:subClassOf obo:CHEBI_24669 , obo:CHEBI_25384 .
obo:GO_0048646 a rdfs:Class ;
rdfs:label "anatomical structure formation involved in morphogenesis" ;
rdfs:comment "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ;
rdfs:subClassOf obo:GO_0032502 .
obo:PHIPO_0000028 a rdfs:Class ;
rdfs:label "normal formation of pathogen penetration structure" ;
rdfs:comment "A single species pathogen growth phenotype in which the formation of the pathogen penetration structure is normal (i.e same as wild-type) when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000160 .
obo:CL_0000596 a rdfs:Class ;
rdfs:label "sexual spore" ;
rdfs:comment "A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature." ;
rdfs:subClassOf obo:CL_0002369 .
obo:PATO_0001905 a rdfs:Class ;
rdfs:label "has normal numbers of parts of type" ;
rdfs:comment "The bearer of this quality has_part = n, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part." ;
rdfs:subClassOf obo:PATO_0001555 .
obo:PR_000001107 a rdfs:Class ;
rdfs:label "D(1)-like dopamine receptor" ;
rdfs:comment "A dopamine receptor that is a product of the DRD1 or DRD5 gene. The active form binds dopamine and its activity is mediated by G proteins that cause activation of adenylate cyclase." ;
rdfs:subClassOf obo:PR_000044633 .
obo:CHEBI_77315 a rdfs:Class ;
rdfs:label "spectinomycin(2+)" ;
rdfs:comment "An organic cation obtained by protonation of the secondary amino groups of spectinomycin." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:PHIPO_0001407 a rdfs:Class ;
rdfs:label "normal growth on dimethomorph" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to dimethomorph (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:UBERON_0003842 a rdfs:Class ;
rdfs:label "neural tube lumen" ;
rdfs:comment "An anatomical space that surrounded_by a neural tube." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:UBERON_0016548 a rdfs:Class ;
rdfs:label "central nervous system gray matter layer" ;
rdfs:comment "A layer of of the central nervous system that is part of gray matter." ;
rdfs:subClassOf obo:UBERON_0022303 .
obo:GO_0002369 a rdfs:Class ;
rdfs:label "T cell cytokine production" ;
rdfs:comment "Any process that contributes to cytokine production by a T cell." ;
rdfs:subClassOf obo:GO_0001816 , obo:GO_0002367 , obo:GO_0002456 .
obo:PHIPO_0000798 a rdfs:Class ;
rdfs:label "sensitive to fenarimol"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenarimol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_23132 a rdfs:Class ;
rdfs:label "chlorobenzenes" ;
rdfs:comment "Any organochlorine compound containing a benzene ring which is substituted by one or more chlorines." ;
rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_36683 .
obo:GO_0002791 a rdfs:Class ;
rdfs:label "regulation of peptide secretion" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of peptide secretion." ;
rdfs:subClassOf obo:GO_0051046 , obo:GO_0065007 , obo:GO_0090087 .
obo:CHEBI_139492 a rdfs:Class ;
rdfs:label "sensitiser" ;
rdfs:comment "A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound." ;
rdfs:subClassOf obo:CHEBI_52209 .
obo:CHEBI_22153 a rdfs:Class ;
rdfs:label "acaricide" ;
rdfs:comment "A substance used to destroy pests of the subclass Acari (mites and ticks)." ;
rdfs:subClassOf obo:CHEBI_25944 .
obo:CHEBI_36976 a rdfs:Class ;
rdfs:label "nucleotide" ;
rdfs:comment "A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid." ;
rdfs:subClassOf obo:CHEBI_25608 .
obo:CHEBI_38179 a rdfs:Class ;
rdfs:label "monocyclic heteroarene" ;
rdfs:subClassOf obo:CHEBI_33833 .
obo:UBERON_0005496 a rdfs:Class ;
rdfs:label "neural tube lateral wall" ;
rdfs:comment "Portion of tissue on the side of the lumen of the neural tube." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0001767 a rdfs:Class ;
rdfs:label "establishment of lymphocyte polarity" ;
rdfs:comment "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell." ;
rdfs:subClassOf obo:GO_0030010 .
obo:CHEBI_16733 a rdfs:Class ;
rdfs:label "D-alpha-amino acid" ;
rdfs:subClassOf obo:CHEBI_83925 .
obo:CHEBI_35497 a rdfs:Class ;
rdfs:label "androgen antagonist" ;
rdfs:comment "A compound which inhibits or antagonises the biosynthesis or actions of androgens." ;
rdfs:subClassOf obo:CHEBI_49020 .
obo:CHEBI_27027 a rdfs:Class ;
rdfs:label "micronutrient" ;
rdfs:comment "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." ;
rdfs:subClassOf obo:CHEBI_33284 .
obo:CHEBI_2955 a rdfs:Class ;
rdfs:label "azithromycin" ;
rdfs:comment "A macrolide antibiotic useful for the treatment of bacterial infections." ;
rdfs:subClassOf obo:CHEBI_25105 , obo:CHEBI_28963 .
obo:CL_0000006 a rdfs:Class ;
rdfs:label "neuronal receptor cell" ;
rdfs:comment "Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception." ;
rdfs:subClassOf obo:CL_0000101 , obo:CL_0000197 , obo:CL_0000540 .
obo:UBERON_0004022 a rdfs:Class ;
rdfs:label "germinal neuroepithelium" ;
rdfs:comment "The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells." ;
rdfs:subClassOf obo:UBERON_0005291 , obo:UBERON_0034706 .
obo:CHEBI_36916 a rdfs:Class ;
rdfs:label "cation" ;
rdfs:comment "A monoatomic or polyatomic species having one or more elementary charges of the proton." ;
rdfs:subClassOf obo:CHEBI_24870 .
obo:CL_0000862 a rdfs:Class ;
rdfs:label "suppressor macrophage" ;
rdfs:comment "A macrophage that suppresses immune responses." ;
rdfs:subClassOf obo:CL_0000861 .
obo:CHEBI_22907 a rdfs:Class ;
rdfs:label "bleomycin" ;
rdfs:comment "A glycopeptide produced by the bacterium Streptomyces verticillus. The term, 'bleomycin' refers to a family of structurally related compounds. When used as an anti-cancer agent, the chemotherapeutical forms are primarily bleomycin A2 and B2." ;
rdfs:subClassOf obo:CHEBI_23089 , obo:CHEBI_24396 .
obo:PHIPO_0000296 a rdfs:Class ;
rdfs:label "obsolete normal dissemination of pathogen asexual product" .
obo:GO_0045940 a rdfs:Class ;
rdfs:label "positive regulation of steroid metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids." ;
rdfs:subClassOf obo:GO_0019218 , obo:GO_0045834 , obo:GO_0065007 .
obo:GO_0051969 a rdfs:Class ;
rdfs:label "regulation of transmission of nerve impulse" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0031644 , obo:GO_0065007 .
obo:CHEBI_22645 a rdfs:Class ;
rdfs:label "arenecarboxamide" ;
rdfs:comment "A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system." ;
rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_62733 .
obo:CHEBI_33694 a rdfs:Class ;
rdfs:label "biomacromolecule" ;
rdfs:comment "A macromolecule formed by a living organism." ;
rdfs:subClassOf obo:CHEBI_33839 , obo:CHEBI_50860 .
obo:PHIPO_0001306 a rdfs:Class ;
rdfs:label "sensitive to salt stress"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to a salt stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide." ;
rdfs:subClassOf obo:PHIPO_0001303 .
obo:GO_0060840 a rdfs:Class ;
rdfs:label "artery development" ;
rdfs:comment "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed." ;
rdfs:subClassOf obo:GO_0001568 , obo:GO_0048856 .
obo:CHEBI_30488 a rdfs:Class ;
rdfs:label "sulfonium" ;
rdfs:subClassOf obo:CHEBI_26830 , obo:CHEBI_33535 , obo:CHEBI_50313 .
obo:CL_0000039 a rdfs:Class ;
rdfs:label "germ line cell" ;
rdfs:comment "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0014856 a rdfs:Class ;
rdfs:label "skeletal muscle cell proliferation" ;
rdfs:comment "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0014855 .
obo:GO_0033046 a rdfs:Class ;
rdfs:label "negative regulation of sister chromatid segregation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." ;
rdfs:subClassOf obo:GO_0033045 , obo:GO_0051985 , obo:GO_0065007 , obo:GO_2001251 .
obo:CL_2000030 a rdfs:Class ;
rdfs:label "hypothalamus cell" ;
rdfs:comment "Any native cell that is part of a hypothalamus." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0002319 .
obo:UBERON_0005662 a rdfs:Class ;
rdfs:label "4th arch ectoderm" ;
rdfs:comment "An ectoderm that is part of a pharyngeal arch 4." ;
rdfs:subClassOf obo:UBERON_0000924 .
obo:GO_0009450 a rdfs:Class ;
rdfs:label "GABA catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA)." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0009063 , obo:GO_0170044 .
obo:GO_2001036 a rdfs:Class ;
rdfs:label "negative regulation of tongue muscle cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902810 , obo:GO_2001035 .
obo:PHIPO_0001137 a rdfs:Class ;
rdfs:label "increased number of hyphal septa"@en ;
rdfs:comment "An individual organism cellular process phenotype in which the number of septa produced during hyphae formation is increased." ;
rdfs:subClassOf obo:PHIPO_0000415 , obo:PHIPO_0000929 .
obo:GO_0001938 a rdfs:Class ;
rdfs:label "positive regulation of endothelial cell proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of endothelial cell proliferation." ;
rdfs:subClassOf obo:GO_0001936 , obo:GO_0050679 , obo:GO_0065007 .
obo:GO_1904074 a rdfs:Class ;
rdfs:label "negative regulation of trophectodermal cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0065007 , obo:GO_1904073 .
obo:CHEBI_51026 a rdfs:Class ;
rdfs:label "macrocycle" ;
rdfs:comment "A cyclic compound containing nine or more atoms as part of the cyclic system." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:UBERON_0003413 a rdfs:Class ;
rdfs:label "pectoral appendage bud mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a pectoral appendage bud." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0010329 .
obo:CHEBI_24669 a rdfs:Class ;
rdfs:label "hydroxy carboxylic acid" ;
rdfs:comment "Any carboxylic acid with at least one hydroxy group." ;
rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_33822 .
obo:GO_0045596 a rdfs:Class ;
rdfs:label "negative regulation of cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0048523 , obo:GO_0051093 , obo:GO_0065007 .
obo:PHIPO_0001358 a rdfs:Class ;
rdfs:label "normal growth on fluopyram" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to fluopyram (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0021983 a rdfs:Class ;
rdfs:label "pituitary gland development" ;
rdfs:comment "The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands." ;
rdfs:subClassOf obo:GO_0048732 , obo:GO_0048856 .
obo:UBERON_0013765 a rdfs:Class ;
rdfs:label "digestive system element" ;
rdfs:comment "Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:GO_0042401 a rdfs:Class ;
rdfs:label "biogenic amine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ;
rdfs:subClassOf obo:GO_0006576 , obo:GO_0009309 .
obo:GO_0002886 a rdfs:Class ;
rdfs:label "regulation of myeloid leukocyte mediated immunity" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity." ;
rdfs:subClassOf obo:GO_0002703 , obo:GO_0065007 .
obo:PHIPO_0001279 a rdfs:Class ;
rdfs:label "abolished peptidase activity"@en ;
rdfs:comment "A single species molecular function phenotype in which a peptidase activity is absent." ;
rdfs:subClassOf obo:PHIPO_0000435 .
obo:CL_2000067 a rdfs:Class ;
rdfs:label "cardiac atrium fibroblast" ;
rdfs:comment "Any fibroblast that is part of a cardiac atrium." ;
rdfs:subClassOf obo:CL_0000057 , obo:CL_0002548 .
obo:CL_0000125 a rdfs:Class ;
rdfs:label "glial cell" ;
rdfs:comment "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." ;
rdfs:subClassOf obo:CL_0000095 .
obo:GO_0009994 a rdfs:Class ;
rdfs:label "oocyte differentiation" ;
rdfs:comment "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0030154 .
obo:CHEBI_24870 a rdfs:Class ;
rdfs:label "ion" ;
rdfs:comment "A molecular entity having a net electric charge." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:CL_4301596 a rdfs:Class ;
rdfs:label "Astro-OLF NN_1 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Prss23 (Mmus), Igfbp2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1166 Astro-OLF NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300360 .
obo:GO_0090068 a rdfs:Class ;
rdfs:label "positive regulation of cell cycle process" ;
rdfs:comment "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0045787 , obo:GO_0065007 .
obo:GO_0140241 a rdfs:Class ;
rdfs:label "translation at synapse" ;
rdfs:comment "Translation that occurs at the synapse." ;
rdfs:subClassOf obo:GO_0006412 .
obo:PHIPO_0000736 a rdfs:Class ;
rdfs:label "sensitive to benznidazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to benznidazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_61120 a rdfs:Class ;
rdfs:label "nucleobase-containing molecular entity" ;
rdfs:comment "Any compound that has a nucleobase as a part." ;
rdfs:subClassOf obo:CHEBI_33833 , obo:CHEBI_51143 .
obo:GO_0140249 a rdfs:Class ;
rdfs:label "protein catabolic process at postsynapse" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0140246 .
obo:UBERON_0010321 a rdfs:Class ;
rdfs:label "skeletal element of eye region" ;
rdfs:comment "A skeletal element that is part of a orbital region." ;
rdfs:subClassOf obo:UBERON_0004765 , obo:UBERON_0010313 .
obo:GO_0005903 a rdfs:Class ;
rdfs:label "brush border" ;
rdfs:comment "The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell." ;
rdfs:subClassOf obo:GO_0098862 .
obo:PHIPO_0001040 a rdfs:Class ;
rdfs:label "obsolete decreased level of a substance in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is lower than normal." .
obo:CHEBI_63944 a rdfs:Class ;
rdfs:label "macrocyclic lactone" ;
rdfs:comment "Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule." ;
rdfs:subClassOf obo:CHEBI_25000 , obo:CHEBI_51026 .
obo:GO_1904146 a rdfs:Class ;
rdfs:label "positive regulation of meiotic cell cycle process involved in oocyte maturation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." ;
rdfs:subClassOf obo:GO_0051446 , obo:GO_0065007 , obo:GO_0090068 , obo:GO_1903538 .
obo:GO_0051153 a rdfs:Class ;
rdfs:label "regulation of striated muscle cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051147 , obo:GO_0065007 .
obo:GO_1902905 a rdfs:Class ;
rdfs:label "positive regulation of supramolecular fiber organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1902903 .
obo:GO_0010761 a rdfs:Class ;
rdfs:label "fibroblast migration" ;
rdfs:comment "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." ;
rdfs:subClassOf obo:GO_0001667 , obo:GO_0016477 .
obo:PHIPO_0000043 a rdfs:Class ;
rdfs:label "abnormal reproduction phenotype"@en ;
rdfs:comment "A single species phenotype where reproduction is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000161 .
obo:GO_0001402 a rdfs:Class ;
rdfs:label "signal transduction involved in filamentous growth" ;
rdfs:comment "Relaying of environmental signals promoting filamentous growth." ;
rdfs:subClassOf obo:GO_0007165 .
a rdfs:Class ;
rdfs:label "Midbrain, sensory related" ;
rdfs:subClassOf obo:BFO_0000004 .
obo:CL_0000099 a rdfs:Class ;
rdfs:label "interneuron" ;
rdfs:comment "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." ;
rdfs:subClassOf obo:CL_2000029 .
obo:PHIPO_0000591 a rdfs:Class ;
rdfs:label "resistance to alexidine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to alexidine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0034489 a rdfs:Class ;
rdfs:label "neutral amino acid transmembrane export from vacuole" ;
rdfs:comment "The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane." ;
rdfs:subClassOf obo:GO_0015804 , obo:GO_0032974 .
obo:GO_0036504 a rdfs:Class ;
rdfs:label "Golgi membrane fusion" ;
rdfs:comment "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane." ;
rdfs:subClassOf obo:GO_0061025 , obo:GO_0090174 .
obo:UBERON_0006314 a rdfs:Class ;
rdfs:label "bodily fluid" ;
rdfs:comment "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." ;
rdfs:subClassOf obo:UBERON_0000463 .
obo:GO_0051251 a rdfs:Class ;
rdfs:label "positive regulation of lymphocyte activation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." ;
rdfs:subClassOf obo:GO_0002696 , obo:GO_0051249 , obo:GO_0065007 .
obo:UBERON_0034995 a rdfs:Class ;
rdfs:label "jaw mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a developing jaw [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:UBERON_0012475 a rdfs:Class ;
rdfs:label "skeleton of pectoral complex" ;
rdfs:comment "The collection of all skeletal elements in a pectoral complex - i.e. the combination of free limb or fin plus pectoral girdle." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:UBERON_0004521 a rdfs:Class ;
rdfs:label "vasculature of muscle organ" ;
rdfs:comment "A vasculature that is part of a muscle organ [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0006876 .
obo:CHEBI_131605 a rdfs:Class ;
rdfs:label "dicarboxylic acid monoester(1-)" ;
rdfs:comment "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a dicarboxylic acid monoester." ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:PHIPO_0000657 a rdfs:Class ;
rdfs:label "resistance to sulbactam"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to sulbactam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0097476 a rdfs:Class ;
rdfs:label "spinal cord motor neuron migration" ;
rdfs:comment "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0097475 .
obo:GO_0051932 a rdfs:Class ;
rdfs:label "synaptic transmission, GABAergic" ;
rdfs:comment "The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ;
rdfs:subClassOf obo:GO_0007268 .
obo:UBERON_0003055 a rdfs:Class ;
rdfs:label "periderm" ;
rdfs:comment "The outermost layer (or layers, depending on the species) of embryonic skin, essential for the development of the epidermis and establishment of the barrier functions. The periderm derives from the outer layer of the ectoderm." ;
rdfs:subClassOf obo:UBERON_0000487 , obo:UBERON_0007376 , obo:UBERON_3000961 .
obo:GO_0060042 a rdfs:Class ;
rdfs:label "retina morphogenesis in camera-type eye" ;
rdfs:comment "The process in which the anatomical structure of the retina is generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_50864 a rdfs:Class ;
rdfs:label "insulin-sensitizing drug" ;
rdfs:comment "An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma)." ;
rdfs:subClassOf obo:CHEBI_35526 , obo:CHEBI_48705 , obo:CHEBI_70781 .
obo:GO_0032229 a rdfs:Class ;
rdfs:label "negative regulation of synaptic transmission, GABAergic" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ;
rdfs:subClassOf obo:GO_0032228 , obo:GO_0050805 , obo:GO_0065007 .
obo:PHIPO_0000977 a rdfs:Class ;
rdfs:label "sensitive to sodium dodecyl sulfate"@en ;
rdfs:comment "A phenotype in which a population of a single-species shows increased sensitivity to sodium dodecyl sulfate (SDS), manifested as an affect on the extent of population growth. (CHEBI:8984)." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0011585 a rdfs:Class ;
rdfs:label "cell condensation" ;
rdfs:comment "Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995)." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:CHEBI_60039 a rdfs:Class ;
rdfs:label "L-proline zwitterion" ;
rdfs:comment "The zwitterion formed from L-proline by proton transfer from the carboxy group to the ring nitrogen. It is the predominant species at physiological pH." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:UBERON_0006757 a rdfs:Class ;
rdfs:label "lateral lingual swelling" ;
rdfs:comment "During the third week there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings (or distal tongue bud) which rise from the inner surface of the mandibular arch and meet in the middle line." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_1901888 a rdfs:Class ;
rdfs:label "regulation of cell junction assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell junction assembly." ;
rdfs:subClassOf obo:GO_0044087 , obo:GO_0051128 , obo:GO_0065007 .
obo:PHIPO_0000572 a rdfs:Class ;
rdfs:label "resistance to bleomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to bleomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0000108 a rdfs:Class ;
rdfs:label "delayed timing of penetration structure formation"@en ;
rdfs:comment "A single species pathogen growth phenotype in which formation of pathogen specialized penetration structure begins later than normal when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000032 .
obo:PHIPO_0000507 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction" .
obo:CHEBI_33659 a rdfs:Class ;
rdfs:label "organic aromatic compound" ;
rdfs:subClassOf obo:CHEBI_33655 , obo:CHEBI_33832 .
obo:GO_0008227 a rdfs:Class ;
rdfs:label "G protein-coupled amine receptor activity" ;
rdfs:comment "Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." ;
rdfs:subClassOf obo:GO_0004930 .
obo:GO_0055008 a rdfs:Class ;
rdfs:label "cardiac muscle tissue morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of cardiac muscle tissue are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060415 .
obo:UBERON_0002165 a rdfs:Class ;
rdfs:label "endocardium" ;
rdfs:comment "The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]." ;
rdfs:subClassOf obo:UBERON_0002523 , obo:UBERON_0004120 , obo:UBERON_0005983 .
obo:CHEBI_35819 a rdfs:Class ;
rdfs:label "branched-chain fatty acid" ;
rdfs:comment "Any fatty acid in which the parent hydrocarbon chain has one or more alkyl substituents; a common component in animal and bacterial lipids. The fatty acyl chain is usually saturated and the substituent a methyl group; however, unsaturated BCFAs are found in marine animals, and branches other than methyl are found in microbial lipids." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:CHEBI_51751 a rdfs:Class ;
rdfs:label "enamide" ;
rdfs:comment "An α,β-unsaturated carboxylic acid amide of general formula R1R2C=CR3‒C(=O)NR4R5 in which the amide C=O function is conjugated to a C=C double bond at the α,β position." ;
rdfs:subClassOf obo:CHEBI_51750 , obo:CHEBI_78840 .
obo:PHIPO_0000564 a rdfs:Class ;
rdfs:label "resistance to mecillinam"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to mecillinam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000692 .
obo:GO_1901653 a rdfs:Class ;
rdfs:label "cellular response to peptide" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_1901652 .
obo:CL_0011001 a rdfs:Class ;
rdfs:label "spinal cord motor neuron" ;
rdfs:comment "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." ;
rdfs:subClassOf obo:CL_0000100 , obo:CL_2000029 .
obo:PHIPO_0000314 a rdfs:Class ;
rdfs:label "obsolete normal effector of virulence suppression of host defense" ;
rdfs:comment "The host defenses suppressed by the pathogen are unaltered compared to the wild type interaction" .
obo:CHEBI_35427 a rdfs:Class ;
rdfs:label "ortho-fused polycyclic hydrocarbon" ;
rdfs:subClassOf obo:CHEBI_33637 .
obo:CHEBI_13643 a rdfs:Class ;
rdfs:label "glycol" ;
rdfs:comment "A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent." ;
rdfs:subClassOf obo:CHEBI_23824 .
obo:UBERON_0002402 a rdfs:Class ;
rdfs:label "pleural cavity" ;
rdfs:comment "The fluid-filled cavity that lies between the visceral and parietal pleurae." ;
rdfs:subClassOf obo:UBERON_0002553 , obo:UBERON_0035809 .
obo:GO_0031109 a rdfs:Class ;
rdfs:label "microtubule polymerization or depolymerization" ;
rdfs:comment "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." ;
rdfs:subClassOf obo:GO_0000226 .
obo:GO_0010657 a rdfs:Class ;
rdfs:label "muscle cell apoptotic process" ;
rdfs:comment "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle." ;
rdfs:subClassOf obo:GO_0006915 .
obo:GO_0019752 a rdfs:Class ;
rdfs:label "carboxylic acid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0043436 .
obo:GO_0002685 a rdfs:Class ;
rdfs:label "regulation of leukocyte migration" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of leukocyte migration." ;
rdfs:subClassOf obo:GO_0002682 , obo:GO_0030334 , obo:GO_0065007 .
obo:CHEBI_37206 a rdfs:Class ;
rdfs:label "hexol" ;
rdfs:comment "A polyol that contains 6 hydroxy groups." ;
rdfs:subClassOf obo:CHEBI_26191 .
obo:GO_0021757 a rdfs:Class ;
rdfs:label "caudate nucleus development" ;
rdfs:comment "The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0048857 .
obo:CHEBI_23697 a rdfs:Class ;
rdfs:label "dichlorobenzene" ;
rdfs:comment "Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions." ;
rdfs:subClassOf obo:CHEBI_23132 .
obo:CHEBI_64272 a rdfs:Class ;
rdfs:label "tunicamycin D2" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 15-methylhexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:CHEBI_33847 a rdfs:Class ;
rdfs:label "monocyclic arene" ;
rdfs:comment "A monocyclic aromatic hydrocarbon." ;
rdfs:subClassOf obo:CHEBI_33658 .
obo:CHEBI_34608 a rdfs:Class ;
rdfs:label "captan" ;
rdfs:comment "A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops." ;
rdfs:subClassOf obo:CHEBI_24897 , obo:CHEBI_33261 , obo:CHEBI_36683 , obo:CHEBI_87198 .
obo:CL_4307037 a rdfs:Class ;
rdfs:label "Astro-NT NN_2 Gm30524 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), A330076C08Rik (Mmus), Fbln5 (Mmus), Mdga2 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Gm30524. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Ventral cochlear nucleus, arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5217 Astro-NT NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301590 .
obo:GO_1905080 a rdfs:Class ;
rdfs:label "negative regulation of cerebellar neuron development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0045665 , obo:GO_0065007 , obo:GO_1905079 .
obo:GO_0046668 a rdfs:Class ;
rdfs:label "regulation of retinal cell programmed cell death" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina." ;
rdfs:subClassOf obo:GO_0043067 , obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0051962 a rdfs:Class ;
rdfs:label "positive regulation of nervous system development" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0051960 , obo:GO_0065007 .
obo:GO_0006914 a rdfs:Class ;
rdfs:label "autophagy" ;
rdfs:comment "The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0061919 .
obo:GO_0034067 a rdfs:Class ;
rdfs:label "protein localization to Golgi apparatus" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0033365 .
obo:GO_0016042 a rdfs:Class ;
rdfs:label "lipid catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." ;
rdfs:subClassOf obo:GO_0006629 , obo:GO_0009056 .
obo:GO_0021549 a rdfs:Class ;
rdfs:label "cerebellum development" ;
rdfs:comment "The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_1904376 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to cell periphery" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903828 , obo:GO_1904375 .
obo:UBERON_0002193 a rdfs:Class ;
rdfs:label "hemolymphoid system" ;
rdfs:comment "Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:GO_2000197 a rdfs:Class ;
rdfs:label "regulation of ribonucleoprotein complex localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization." ;
rdfs:subClassOf obo:GO_0060341 , obo:GO_0065007 .
obo:CHEBI_17544 a rdfs:Class ;
rdfs:label "hydrogencarbonate" ;
rdfs:comment "The carbon oxoanion resulting from the removal of a proton from carbonic acid." ;
rdfs:subClassOf obo:CHEBI_35604 .
obo:CL_4023026 a rdfs:Class ;
rdfs:label "direct pathway medium spiny neuron" ;
rdfs:comment "A GABAergic medium spiny neuron located in the striatum that gives rise to the direct basal ganglia pathway. It projects directly to the GPi and SNr, where it inhibits tonically active GABAergic output neurons to disinhibit thalamic and brainstem motor targets (Gerfen. 2023). In mice and humans, this cell selectively expresses the D1 dopamine receptor (DRD1), which couples to stimulatory G-proteins (Gs/Gαolf) to increase cAMP and activate PKA-dependent signaling cascades (Gerfen et al., 1990; Kebabian & Calne, 1979). Functionally, activation of this cell promotes selected motor actions by disinhibiting thalamic and midbrain motor centers (Mink, 1996; Cui et al., 2013)." ;
rdfs:subClassOf obo:CL_1001474 .
obo:CHEBI_37153 a rdfs:Class ;
rdfs:label "EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor" ;
rdfs:comment "Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16)." ;
rdfs:subClassOf obo:CHEBI_76775 .
obo:PHIPO_0000966 a rdfs:Class ;
rdfs:label "pathogen penetration structure present"@en ;
rdfs:comment "A single species pathogen growth phenotype in which the pathogen specialized host penetration structure is present when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000028 .
obo:GO_0015695 a rdfs:Class ;
rdfs:label "organic cation transport" ;
rdfs:comment "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." ;
rdfs:subClassOf obo:GO_0006810 .
obo:GO_0098588 a rdfs:Class ;
rdfs:label "bounding membrane of organelle" ;
rdfs:comment "The lipid bilayer that forms the outer-most layer of an organelle." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031090 .
obo:GO_0021853 a rdfs:Class ;
rdfs:label "cerebral cortex GABAergic interneuron migration" ;
rdfs:comment "The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0021830 , obo:GO_1904936 .
obo:PATO_0000516 a rdfs:Class ;
rdfs:label "sensitive toward" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's having sensitivity toward an external stimulus." ;
rdfs:subClassOf obo:PATO_0000085 .
obo:GO_0043001 a rdfs:Class ;
rdfs:label "Golgi to plasma membrane protein transport" ;
rdfs:comment "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. Golgi to plasma membrane transport precedes exocytosis." ;
rdfs:subClassOf obo:GO_0006893 , obo:GO_0015031 , obo:GO_0061951 .
obo:CHEBI_23377 a rdfs:Class ;
rdfs:label "copper molecular entity" ;
rdfs:subClassOf obo:CHEBI_33745 .
obo:GO_0086016 a rdfs:Class ;
rdfs:label "AV node cell action potential" ;
rdfs:comment "An action potential that occurs in an atrioventricular node cardiac muscle cell." ;
rdfs:subClassOf obo:GO_0001508 , obo:GO_0086001 .
obo:GO_0010648 a rdfs:Class ;
rdfs:label "negative regulation of cell communication" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0048523 , obo:GO_0065007 .
obo:GO_0031974 a rdfs:Class ;
rdfs:label "membrane-enclosed lumen" ;
rdfs:comment "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." ;
rdfs:subClassOf obo:GO_0110165 .
obo:UBERON_0004242 a rdfs:Class ;
rdfs:label "bronchus smooth muscle" ;
rdfs:comment "A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004233 .
obo:CHEBI_33582 a rdfs:Class ;
rdfs:label "carbon group molecular entity" ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:GO_0002709 a rdfs:Class ;
rdfs:label "regulation of T cell mediated immunity" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of T cell mediated immunity." ;
rdfs:subClassOf obo:GO_0002706 , obo:GO_0002822 , obo:GO_0065007 .
obo:CL_0000081 a rdfs:Class ;
rdfs:label "blood cell" ;
rdfs:comment "A cell found predominately in the blood." ;
rdfs:subClassOf obo:CL_0000988 .
obo:CHEBI_33653 a rdfs:Class ;
rdfs:label "aliphatic compound" ;
rdfs:comment "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds." ;
rdfs:subClassOf obo:CHEBI_50860 .
obo:UBERON_0000488 a rdfs:Class ;
rdfs:label "atypical epithelium" ;
rdfs:comment "Epithelium that consists of epithelial cells not arranged in one ore more layers." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0021686 a rdfs:Class ;
rdfs:label "cerebellar granular layer maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:UBERON_0003066 a rdfs:Class ;
rdfs:label "pharyngeal arch 2" ;
rdfs:comment "The second pharyngeal arch will form the hyoid apparatus. The cranial neural crest cells that populate the second pharyngeal arch emerge primarily from rhombomere 4 and will form skeletal elements." ;
rdfs:subClassOf obo:UBERON_0002539 .
obo:CHEBI_47880 a rdfs:Class ;
rdfs:label "steroid ester" ;
rdfs:subClassOf obo:CHEBI_35341 , obo:CHEBI_35701 .
obo:UBERON_0014614 a rdfs:Class ;
rdfs:label "cervical spinal cord white matter" ;
rdfs:comment "A white matter of spinal cord that is part of a cervical spinal cord." ;
rdfs:subClassOf obo:UBERON_0002318 .
obo:UBERON_0001886 a rdfs:Class ;
rdfs:label "choroid plexus" ;
rdfs:comment "A network formed by blood vessels and the tela choroidea which secretes CSF into the ventricular spaces." ;
rdfs:subClassOf obo:UBERON_0003947 , obo:UBERON_0005629 , obo:UBERON_0006876 , obo:UBERON_0036303 .
obo:CHEBI_72768 a rdfs:Class ;
rdfs:label "aryl hydrocarbon receptor agonist" ;
rdfs:comment "An agonist that binds to and activates aryl hydrocarbon receptors (AhRs)." ;
rdfs:subClassOf obo:CHEBI_48705 .
obo:GO_0043254 a rdfs:Class ;
rdfs:label "regulation of protein-containing complex assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein complex assembly." ;
rdfs:subClassOf obo:GO_0044087 , obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0003160 a rdfs:Class ;
rdfs:label "endocardium morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_2000791 a rdfs:Class ;
rdfs:label "negative regulation of mesenchymal cell proliferation involved in lung development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_0072201 .
obo:GO_0021534 a rdfs:Class ;
rdfs:label "cell proliferation in hindbrain" ;
rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0061351 .
obo:UBERON_0005366 a rdfs:Class ;
rdfs:label "olfactory lobe" ;
rdfs:comment "The lobe at the anterior part of each cerebral hemisphere, responsible for olfactory functions." ;
rdfs:subClassOf obo:UBERON_0016526 .
obo:CHEBI_51061 a rdfs:Class ;
rdfs:label "hormone receptor modulator" ;
rdfs:comment "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." ;
rdfs:subClassOf obo:CHEBI_90710 .
obo:CHEBI_24848 a rdfs:Class ;
rdfs:label "inositol" ;
rdfs:comment "Any cyclohexane-1,2,3,4,5,6-hexol." ;
rdfs:subClassOf obo:CHEBI_23451 , obo:CHEBI_37206 .
obo:GO_0010002 a rdfs:Class ;
rdfs:label "cardioblast differentiation" ;
rdfs:comment "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0035051 , obo:GO_0048863 .
obo:UBERON_0003080 a rdfs:Class ;
rdfs:label "anterior neural tube" ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0072666 a rdfs:Class ;
rdfs:label "establishment of protein localization to vacuole" ;
rdfs:comment "The directed movement of a protein to a specific location in a vacuole." ;
rdfs:subClassOf obo:GO_0045184 , obo:GO_0072594 , obo:GO_0072665 .
obo:PHIPO_0000235 a rdfs:Class ;
rdfs:label "localization phenotype"@en ;
rdfs:comment "A single species phenotype that affects the localization of a structure or substance in a cell." ;
rdfs:subClassOf obo:PHIPO_0000034 .
obo:GO_0010605 a rdfs:Class ;
rdfs:label "negative regulation of macromolecule metabolic process" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009892 , obo:GO_0060255 , obo:GO_0065007 .
obo:GO_0060428 a rdfs:Class ;
rdfs:label "lung epithelium development" ;
rdfs:comment "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060429 .
obo:GO_0030595 a rdfs:Class ;
rdfs:label "leukocyte chemotaxis" ;
rdfs:comment "The movement of a leukocyte in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0050900 , obo:GO_0060326 .
obo:GO_0046889 a rdfs:Class ;
rdfs:label "positive regulation of lipid biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ;
rdfs:subClassOf obo:GO_0009891 , obo:GO_0045834 , obo:GO_0046890 , obo:GO_0065007 .
obo:PHIPO_0000203 a rdfs:Class ;
rdfs:label "obsolete increased aerial height of filamentous colony affecting colony shape" ;
rdfs:comment "A single species hyphal colony shape phenotype where the aerial height of the filamentous colony is increased." .
obo:GO_0030048 a rdfs:Class ;
rdfs:label "actin filament-based movement" ;
rdfs:comment "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." ;
rdfs:subClassOf obo:GO_0030029 .
obo:UBERON_0008823 a rdfs:Class ;
rdfs:label "neural tube derived brain" ;
rdfs:comment "A brain that develops_from a neural tube." ;
rdfs:subClassOf obo:UBERON_0000489 , obo:UBERON_0000955 .
obo:GO_0022030 a rdfs:Class ;
rdfs:label "telencephalon glial cell migration" ;
rdfs:comment "The orderly movement of glial cells through the telencephalon." ;
rdfs:subClassOf obo:GO_0008347 , obo:GO_0022029 .
obo:UBERON_0009712 a rdfs:Class ;
rdfs:label "endocardium of right ventricle" ;
rdfs:comment "Any endocardium that is part of the right ventricle of the heart." ;
rdfs:subClassOf obo:UBERON_0001081 .
obo:UBERON_0015238 a rdfs:Class ;
rdfs:label "pineal complex" ;
rdfs:comment "A cluster in the epithalamus that consists of the pineal body and any associated structures, such as the parapineal gland or the parietal organ. The complex is poorly developed in mammals." ;
rdfs:subClassOf obo:UBERON_0000477 .
obo:UBERON_0036264 a rdfs:Class ;
rdfs:label "zygomaticotemporal nerve" ;
rdfs:comment "The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit." ;
rdfs:subClassOf obo:UBERON_0011779 .
obo:GO_0002070 a rdfs:Class ;
rdfs:label "epithelial cell maturation" ;
rdfs:comment "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0048469 .
obo:GO_0099519 a rdfs:Class ;
rdfs:label "dense core granule cytoskeletal transport" ;
rdfs:comment "The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments." ;
rdfs:subClassOf obo:GO_0046907 , obo:GO_0099518 , obo:GO_1901950 .
obo:GO_0120192 a rdfs:Class ;
rdfs:label "tight junction assembly" ;
rdfs:comment "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." ;
rdfs:subClassOf obo:GO_0007043 , obo:GO_0022607 , obo:GO_0120193 .
obo:UBERON_0011777 a rdfs:Class ;
rdfs:label "nucleus of spinal cord" ;
rdfs:comment "A neural nucleus that is part of the spinal cord." ;
rdfs:subClassOf obo:UBERON_0000125 .
obo:GO_1902683 a rdfs:Class ;
rdfs:label "regulation of receptor localization to synapse" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of receptor localization to synapse." ;
rdfs:subClassOf obo:GO_0032879 , obo:GO_0065007 .
obo:GO_0042175 a rdfs:Class ;
rdfs:label "nuclear outer membrane-endoplasmic reticulum membrane network" ;
rdfs:comment "The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane." ;
rdfs:subClassOf obo:GO_0016020 .
obo:GO_0099156 a rdfs:Class ;
rdfs:label "cell-cell signaling via exosome" ;
rdfs:comment "Cell-cell signaling in which the ligand is carried between cells by an exosome." ;
rdfs:subClassOf obo:GO_0007267 .
obo:GO_0010470 a rdfs:Class ;
rdfs:label "regulation of gastrulation" ;
rdfs:comment "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0045995 , obo:GO_0065007 .
obo:PHIPO_0000025 a rdfs:Class ;
rdfs:label "obsolete normal mating phenotype prior to penetration" ;
rdfs:comment "Is this a bit too specific? should this be with sexual reproduction? eg ustilago and rust fungus MU agrees REMOVE from penetration" .
obo:CL_4042040 a rdfs:Class ;
rdfs:label "glutamatergic neuron of the basal ganglia"@en ;
rdfs:comment "A glutametergic neuron with its soma located in a basal ganglia. This neuron type is involved in motor control, decision making and learning." ;
rdfs:subClassOf obo:CL_0000679 , obo:CL_2000029 .
obo:GO_1905207 a rdfs:Class ;
rdfs:label "regulation of cardiocyte differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardiocyte differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:UBERON_0002530 a rdfs:Class ;
rdfs:label "gland" ;
rdfs:comment "An organ that functions as a secretory or excretory organ." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:PR_P32648 a rdfs:Class ;
rdfs:label "VIP peptides (mouse)" ;
rdfs:comment "A VIP peptides that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000017299 , obo:PR_000029032 .
obo:PHIPO_0001386 a rdfs:Class ;
rdfs:label "sensitive to phenamacril" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to phenamacril. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0010759 a rdfs:Class ;
rdfs:label "positive regulation of macrophage chemotaxis" ;
rdfs:comment "Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0002690 , obo:GO_0010758 , obo:GO_0065007 , obo:GO_0071622 , obo:GO_1905523 .
obo:GO_0120305 a rdfs:Class ;
rdfs:label "regulation of pigmentation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:CHEBI_24676 a rdfs:Class ;
rdfs:label "hydroxybenzoic acid" ;
rdfs:comment "Any benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring." ;
rdfs:subClassOf obo:CHEBI_22723 , obo:CHEBI_33853 .
obo:CHEBI_63409 a rdfs:Class ;
rdfs:label "pentose derivative" ;
rdfs:comment "A monosaccharide derivative that is formally obtained from a pentose." ;
rdfs:subClassOf obo:CHEBI_63367 .
obo:CHEBI_35363 a rdfs:Class ;
rdfs:label "carbohydrazide" ;
rdfs:comment "A hydrazide consisting of hydrazine carrying one or more carboacyl groups." ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_35362 .
obo:GO_0045649 a rdfs:Class ;
rdfs:label "regulation of macrophage differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of macrophage differentiation." ;
rdfs:subClassOf obo:GO_0002761 , obo:GO_0065007 .
obo:GO_0001756 a rdfs:Class ;
rdfs:label "somitogenesis" ;
rdfs:comment "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." ;
rdfs:subClassOf obo:GO_0009952 , obo:GO_0035282 , obo:GO_0048646 .
obo:GO_0007268 a rdfs:Class ;
rdfs:label "chemical synaptic transmission" ;
rdfs:comment "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ;
rdfs:subClassOf obo:GO_0098916 .
obo:GO_2001035 a rdfs:Class ;
rdfs:label "regulation of tongue muscle cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902809 .
obo:UBERON_0009616 a rdfs:Class ;
rdfs:label "presumptive midbrain" ;
rdfs:comment "A presumptive structure that has the potential to develop into a midbrain." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:UBERON_0000153 a rdfs:Class ;
rdfs:label "anterior region of body" ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:CHEBI_39430 a rdfs:Class ;
rdfs:label "dioxolane" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 .
obo:GO_0002275 a rdfs:Class ;
rdfs:label "myeloid cell activation involved in immune response" ;
rdfs:comment "A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0002274 , obo:GO_0002366 .
obo:UBERON_0005983 a rdfs:Class ;
rdfs:label "heart layer" ;
rdfs:comment "The laminar structure of the heart." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:GO_0021903 a rdfs:Class ;
rdfs:label "rostrocaudal neural tube patterning" ;
rdfs:comment "The process in which the neural tube is divided into specific regions along the rostrocaudal axis." ;
rdfs:subClassOf obo:GO_0009952 .
obo:GO_0060935 a rdfs:Class ;
rdfs:label "cardiac fibroblast cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0035051 .
obo:CHEBI_39214 a rdfs:Class ;
rdfs:label "abamectin" ;
rdfs:comment "Mixture of 80% avermectin B1a and 20% avermectin B1b." ;
rdfs:subClassOf obo:CHEBI_39213 , obo:CHEBI_39219 , obo:CHEBI_60004 .
obo:GO_1904115 a rdfs:Class ;
rdfs:label "axon cytoplasm" ;
rdfs:comment "Any cytoplasm that is part of a axon." ;
rdfs:subClassOf obo:GO_0005737 , obo:GO_0120111 .
obo:GO_0070130 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial translation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ;
rdfs:subClassOf obo:GO_0017148 , obo:GO_0065007 , obo:GO_0070129 .
obo:GO_0061515 a rdfs:Class ;
rdfs:label "myeloid cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0030097 , obo:GO_0048468 .
obo:UBERON_0036654 a rdfs:Class ;
rdfs:label "wall of lateral ventricle" ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0036661 .
a rdfs:Class ;
rdfs:label "choroid plexus" ;
rdfs:subClassOf , obo:UBERON_0001886 , obo:UBERON_0002200 , obo:UBERON_0002307 .
obo:CHEBI_61293 a rdfs:Class ;
rdfs:label "adenyl nucleotide" ;
rdfs:comment "A nucleotide having adenine as the base." ;
rdfs:subClassOf obo:CHEBI_26395 .
obo:CHEBI_32588 a rdfs:Class ;
rdfs:label "potassium chloride" ;
rdfs:comment "A metal chloride salt with a K(+) counterion." ;
rdfs:subClassOf obo:CHEBI_190303 , obo:CHEBI_36093 , obo:CHEBI_50860 .
obo:GO_0002062 a rdfs:Class ;
rdfs:label "chondrocyte differentiation" ;
rdfs:comment "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0005739 a rdfs:Class ;
rdfs:label "mitochondrion" ;
rdfs:comment "A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." ;
rdfs:subClassOf obo:GO_0043231 .
obo:PHIPO_0000927 a rdfs:Class ;
rdfs:label "host defense-induced reactive oxygen species present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host reactive oxygen species (ROS) often associated with an oxidative burst response during infection is present." ;
rdfs:subClassOf obo:PHIPO_0000924 .
obo:UBERON_0004478 a rdfs:Class ;
rdfs:label "musculature of larynx" ;
rdfs:comment "The collection of muscles that are part of the larynx." ;
rdfs:subClassOf obo:UBERON_0001015 .
obo:GO_0070851 a rdfs:Class ;
rdfs:label "growth factor receptor binding" ;
rdfs:comment "Binding to a growth factor receptor." ;
rdfs:subClassOf obo:GO_0005102 .
obo:CL_0000226 a rdfs:Class ;
rdfs:label "single nucleate cell" ;
rdfs:comment "A cell with a single nucleus." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 , obo:CL_0002242 .
obo:CHEBI_47891 a rdfs:Class ;
rdfs:label "steroid acid" ;
rdfs:comment "Any steroid substituted by at least one carboxy group." ;
rdfs:subClassOf obo:CHEBI_35341 , obo:CHEBI_64709 .
obo:CHEBI_87034 a rdfs:Class ;
rdfs:label "aromatic fungicide" ;
rdfs:comment "An organic aromatic compound that has been used as a fungicide." ;
rdfs:subClassOf obo:CHEBI_33659 .
obo:PHIPO_0000154 a rdfs:Class ;
rdfs:label "abolished RNA binding"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which RNA binding by a gene product does not occur, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000152 .
obo:CHEBI_15734 a rdfs:Class ;
rdfs:label "primary alcohol" ;
rdfs:comment "A primary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." ;
rdfs:subClassOf obo:CHEBI_30879 .
obo:CHEBI_33434 a rdfs:Class ;
rdfs:label "elemental halogen" ;
rdfs:subClassOf obo:CHEBI_33259 .
obo:GO_0014902 a rdfs:Class ;
rdfs:label "myotube differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0051146 .
obo:GO_0021675 a rdfs:Class ;
rdfs:label "nerve development" ;
rdfs:comment "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:CHEBI_7025 a rdfs:Class ;
rdfs:label "mupirocin" ;
rdfs:comment "An α,β-unsaturated ester resulting from the formal condensation of the alcoholic hydroxy group of 9-hydroxynonanoic acid with the carboxy group of (2E)-4-[(2S)-tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoic acid in which the tetrahydropyranyl ring is substituted at positions 3 and 4 by hydroxy groups and at position 5 by a {(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl group. Originally isolated from the Gram-negative bacterium Pseudomonas fluorescens, it is used as a topical antibiotic for the treatment of Gram-positive bacterial infections." ;
rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_27136 , obo:CHEBI_32955 , obo:CHEBI_35681 , obo:CHEBI_46942 , obo:CHEBI_51737 .
obo:GO_0051234 a rdfs:Class ;
rdfs:label "establishment of localization" ;
rdfs:comment "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." ;
rdfs:subClassOf obo:GO_0051179 .
obo:GO_0001777 a rdfs:Class ;
rdfs:label "T cell homeostatic proliferation" ;
rdfs:comment "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0042098 .
obo:CHEBI_35983 a rdfs:Class ;
rdfs:label "7-oxo monocarboxylic acid" ;
rdfs:subClassOf obo:CHEBI_35871 .
obo:GO_0071555 a rdfs:Class ;
rdfs:label "cell wall organization" ;
rdfs:comment "A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis." ;
rdfs:subClassOf obo:GO_0045229 , obo:GO_0071554 .
obo:CHEBI_59672 a rdfs:Class ;
rdfs:label "EC 2.4.1.16 (chitin synthase) inhibitor" ;
rdfs:comment "A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16)." ;
rdfs:subClassOf obo:CHEBI_76789 .
obo:CHEBI_39208 a rdfs:Class ;
rdfs:label "antibiotic insecticide" ;
rdfs:subClassOf obo:CHEBI_24852 , obo:CHEBI_39215 .
obo:CHEBI_63598 a rdfs:Class ;
rdfs:label "levofloxacin" ;
rdfs:comment "An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase." ;
rdfs:subClassOf obo:CHEBI_194135 , obo:CHEBI_26513 , obo:CHEBI_86324 , obo:CHEBI_87211 .
obo:UBERON_0010136 a rdfs:Class ;
rdfs:label "epithelial sheet" ;
rdfs:comment "An epithelial sheet is a flat surface consisting of closely packed epithelial cells." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0051623 a rdfs:Class ;
rdfs:label "positive regulation of norepinephrine uptake" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell." ;
rdfs:subClassOf obo:GO_0051050 , obo:GO_0051621 , obo:GO_0065007 .
obo:GO_0045638 a rdfs:Class ;
rdfs:label "negative regulation of myeloid cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0045637 , obo:GO_0065007 .
obo:PATO_0070025 a rdfs:Class ;
rdfs:label "unipolar neuron morphology" ;
rdfs:comment "A cell morphology that inheres in neurons with only one process, a neurite, that extends from the cell body. The neurite then branches to form dendritic and axonal processes." ;
rdfs:subClassOf obo:PATO_0010006 .
obo:GO_0048468 a rdfs:Class ;
rdfs:label "cell development" ;
rdfs:comment "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." ;
rdfs:subClassOf obo:GO_0008150 , obo:GO_0048856 , obo:GO_0048869 .
obo:PHIPO_0001347 a rdfs:Class ;
rdfs:label "normal growth on bitertanol" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to bitertanol (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0006900 a rdfs:Class ;
rdfs:label "vesicle budding from membrane" ;
rdfs:comment "The evagination of a membrane, resulting in formation of a vesicle." ;
rdfs:subClassOf obo:GO_0016050 , obo:GO_0061024 .
obo:UBERON_0014402 a rdfs:Class ;
rdfs:label "sex-specific anatomical structure" ;
rdfs:comment "A part of the body present only in a specific gender." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0099738 a rdfs:Class ;
rdfs:label "cell cortex region" ;
rdfs:comment "The complete extent of cell cortex that underlies some some region of the plasma membrane." ;
rdfs:subClassOf obo:GO_0005938 , obo:GO_0099568 .
obo:GO_0060350 a rdfs:Class ;
rdfs:label "endochondral bone morphogenesis" ;
rdfs:comment "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone." ;
rdfs:subClassOf obo:GO_0060349 .
obo:PHIPO_0000876 a rdfs:Class ;
rdfs:label "sensitive to furazolidone"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to furazolidone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000271 a rdfs:Class ;
rdfs:label "normal protein localization to nucleus"@en ;
rdfs:comment "A single organism phenotype in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type)(GO:0034504)." ;
rdfs:subClassOf obo:PHIPO_0000269 .
obo:UBERON_0001774 a rdfs:Class ;
rdfs:label "skeletal muscle of trunk" ;
rdfs:comment "A skeletal muscle organ that is part of the trunk region." ;
rdfs:subClassOf obo:UBERON_0005177 , obo:UBERON_0014892 .
obo:GO_0019221 a rdfs:Class ;
rdfs:label "cytokine-mediated signaling pathway" ;
rdfs:comment "The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription." ;
rdfs:subClassOf obo:GO_0007166 .
obo:CHEBI_87230 a rdfs:Class ;
rdfs:label "nitrofuran antibiotic" ;
rdfs:comment "A member of the class of furans in which the furan ring is substituted by a nitro group and which also has significant antibiotic properties." ;
rdfs:subClassOf obo:CHEBI_24129 , obo:CHEBI_25558 , obo:CHEBI_25807 , obo:CHEBI_35716 .
obo:CHEBI_29337 a rdfs:Class ;
rdfs:label "azanide" ;
rdfs:subClassOf obo:CHEBI_35106 , obo:CHEBI_79389 .
obo:CHEBI_64996 a rdfs:Class ;
rdfs:label "EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor" ;
rdfs:comment "A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33)." ;
rdfs:subClassOf obo:CHEBI_35856 .
obo:PHIPO_0001260 a rdfs:Class ;
rdfs:label "host cell viable with pathogen"@en ;
rdfs:comment "A host cell viability phenotype where the host cell survives in the presence of the pathogen." ;
rdfs:subClassOf obo:PHIPO_0001259 .
obo:UBERON_0003558 a rdfs:Class ;
rdfs:label "diencephalon arachnoid mater" ;
rdfs:comment "An arachnoid mater that is part of a diencephalon [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002362 , obo:UBERON_0003290 , obo:UBERON_0003556 .
obo:GO_0110141 a rdfs:Class ;
rdfs:label "L-glutamate import into mitochondrion" ;
rdfs:comment "The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0010496 , obo:GO_0015813 .
obo:GO_0120262 a rdfs:Class ;
rdfs:label "negative regulation of heterochromatin organization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120261 , obo:GO_1905268 .
obo:UBERON_0002514 a rdfs:Class ;
rdfs:label "intramembranous bone" ;
rdfs:comment "Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." ;
rdfs:subClassOf obo:UBERON_0001474 .
obo:UBERON_0007647 a rdfs:Class ;
rdfs:label "ectomeninx" ;
rdfs:comment "The outermost layer of the mesenchymal capsule that surrounds the developing brain, of mixed paraxial mesoderm and neural crest origin. The ectomeninx forms the dura mater (both inner layer and outer chondrogenic layer)." ;
rdfs:subClassOf obo:UBERON_0007645 .
obo:GO_0045184 a rdfs:Class ;
rdfs:label "establishment of protein localization" ;
rdfs:comment "The directed movement of a protein to a specific location." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0051234 .
obo:GO_0003214 a rdfs:Class ;
rdfs:label "cardiac left ventricle morphogenesis" ;
rdfs:comment "The process in which the left cardiac ventricle is generated and organized." ;
rdfs:subClassOf obo:GO_0003208 , obo:GO_0009653 .
obo:CL_4307111 a rdfs:Class ;
rdfs:label "OEC NN_1 A330076C08Rik olfactory ensheathing cell (Mmus)" ;
rdfs:comment "A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Mybpc1 (Mmus), Syk (Mmus). It is distinguished from other OEC cells by expression of A330076C08Rik. These cells are located in the Olfactory areas, brain , in or close to the regions: olfactory nerve layer of main olfactory bulb, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5291 OEC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301615 .
obo:CHEBI_59647 a rdfs:Class ;
rdfs:label "EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor" ;
rdfs:comment "An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of serine palmitoyltransferase (EC 2.3.1.50)." ;
rdfs:subClassOf obo:CHEBI_76878 .
obo:GO_0048858 a rdfs:Class ;
rdfs:label "cell projection morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a cell projection are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0030030 .
obo:PR_P06800 a rdfs:Class ;
rdfs:label "receptor-type tyrosine-protein phosphatase C (mouse)" ;
rdfs:comment "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001006 , obo:PR_000029032 .
obo:GO_0005923 a rdfs:Class ;
rdfs:label "bicellular tight junction" ;
rdfs:comment "An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes." ;
rdfs:subClassOf obo:GO_0070160 .
a rdfs:Class ;
rdfs:label "Olfactory tubercle" ;
rdfs:subClassOf , obo:UBERON_0001883 .
obo:CHEBI_59163 a rdfs:Class ;
rdfs:label "biomarker" ;
rdfs:comment "A substance used as an indicator of a biological state." ;
rdfs:subClassOf obo:CHEBI_47867 .
obo:PR_000002112 a rdfs:Class ;
rdfs:label "vascular endothelial growth factor receptor 2" ;
rdfs:comment "A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001971 .
obo:GO_0010549 a rdfs:Class ;
rdfs:label "regulation of membrane disassembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of membrane disassembly." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0009582 a rdfs:Class ;
rdfs:label "detection of abiotic stimulus" ;
rdfs:comment "The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0009628 , obo:GO_0051606 .
obo:GO_0000791 a rdfs:Class ;
rdfs:label "euchromatin" ;
rdfs:comment "A dispersed and relatively uncompacted form of chromatin that is in a transcription-competent conformation." ;
rdfs:subClassOf obo:GO_0000785 .
obo:CL_0000209 a rdfs:Class ;
rdfs:label "taste receptor cell" ;
rdfs:comment "A specialized cell involved in gustatory sensory perception." ;
rdfs:subClassOf obo:CL_0000098 , obo:CL_0000206 , obo:CL_0002076 .
obo:GO_0048731 a rdfs:Class ;
rdfs:label "system development" ;
rdfs:comment "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0048020 a rdfs:Class ;
rdfs:label "CCR chemokine receptor binding" ;
rdfs:comment "Binding to a CCR chemokine receptor." ;
rdfs:subClassOf obo:GO_0042379 .
obo:GO_1904028 a rdfs:Class ;
rdfs:label "positive regulation of collagen fibril organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of collagen fibril organization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903055 , obo:GO_1904026 .
obo:CHEBI_50906 a rdfs:Class ;
rdfs:label "role" ;
rdfs:comment "A role is particular behaviour which a material entity may exhibit." .
obo:CHEBI_32964 a rdfs:Class ;
rdfs:label "ornithinate" ;
rdfs:subClassOf obo:CHEBI_33558 .
obo:GO_0061526 a rdfs:Class ;
rdfs:label "acetylcholine secretion" ;
rdfs:comment "The regulated release of acetylcholine by a cell." ;
rdfs:subClassOf obo:GO_0015870 , obo:GO_0023061 , obo:GO_0046903 .
obo:CHEBI_52064 a rdfs:Class ;
rdfs:label "methicillin(1-)" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:CHEBI_36756 a rdfs:Class ;
rdfs:label "farnesane" ;
rdfs:comment "A sesquiterpene that is dodecane substituted by methyl groups at positions 2, 6 and 10." ;
rdfs:subClassOf obo:CHEBI_18310 , obo:CHEBI_35189 .
obo:GO_0099075 a rdfs:Class ;
rdfs:label "mitochondrion-derived vesicle mediated transport" ;
rdfs:comment "Vesicle-mediated transport of cargo from the mitochondrion by a mitochondrion-derived vesicle." ;
rdfs:subClassOf obo:GO_0016192 .
obo:UBERON_0003836 a rdfs:Class ;
rdfs:label "abdominal segment skin" ;
rdfs:comment "A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0001085 .
obo:GO_1901552 a rdfs:Class ;
rdfs:label "positive regulation of endothelial cell development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endothelial cell development." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0065007 , obo:GO_1901550 .
obo:UBERON_0003494 a rdfs:Class ;
rdfs:label "respiratory system venule" ;
rdfs:comment "A venule that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001979 , obo:UBERON_0003504 .
obo:PATO_0002304 a rdfs:Class ;
rdfs:label "increased process quality" ;
rdfs:comment "A quality of a process that has a value that is increased compared to normal or average." ;
rdfs:subClassOf obo:PATO_0001236 , obo:PATO_0002300 .
obo:GO_0048341 a rdfs:Class ;
rdfs:label "paraxial mesoderm formation" ;
rdfs:comment "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0001707 , obo:GO_0048646 .
obo:GO_0014016 a rdfs:Class ;
rdfs:label "neuroblast differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0090316 a rdfs:Class ;
rdfs:label "positive regulation of intracellular protein transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." ;
rdfs:subClassOf obo:GO_0032388 , obo:GO_0033157 , obo:GO_0051222 , obo:GO_0065007 .
a rdfs:Class ;
rdfs:label "Medulla, motor related" ;
rdfs:subClassOf obo:BFO_0000004 .
obo:GO_0019226 a rdfs:Class ;
rdfs:label "transmission of nerve impulse" ;
rdfs:comment "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." ;
rdfs:subClassOf obo:GO_0050877 .
obo:GO_0071711 a rdfs:Class ;
rdfs:label "basement membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0030198 .
obo:UBERON_0009196 a rdfs:Class ;
rdfs:label "indifferent external genitalia" ;
rdfs:subClassOf obo:UBERON_0004176 .
obo:GO_2000171 a rdfs:Class ;
rdfs:label "negative regulation of dendrite development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development." ;
rdfs:subClassOf obo:GO_0010977 , obo:GO_0050773 , obo:GO_0051093 , obo:GO_0065007 .
obo:PHIPO_0001220 a rdfs:Class ;
rdfs:label "physical quality phenotype"@en ;
rdfs:comment "A phenotype that affects any physical object quality, such as morphology, number, location, etc., of an individual, tissue, cell, or cellular component." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:UBERON_0002149 a rdfs:Class ;
rdfs:label "superior salivatory nucleus" ;
rdfs:comment "Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703)." ;
rdfs:subClassOf obo:UBERON_0000126 , obo:UBERON_0004121 , obo:UBERON_0004133 , obo:UBERON_0007635 .
obo:PHIPO_0000290 a rdfs:Class ;
rdfs:label "obsolete colour present" .
obo:GO_0097212 a rdfs:Class ;
rdfs:label "lysosomal membrane organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0061024 .
obo:UBERON_0005206 a rdfs:Class ;
rdfs:label "choroid plexus stroma" ;
rdfs:comment "Stromal matrix surrounding blood vessels within the choroid plexus." ;
rdfs:subClassOf obo:UBERON_0003891 .
obo:CL_0000092 a rdfs:Class ;
rdfs:label "osteoclast" ;
rdfs:comment "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive." ;
rdfs:subClassOf obo:CL_0000518 , obo:CL_0000766 , obo:CL_0001035 .
obo:UBERON_8480074 a rdfs:Class ;
rdfs:label "skin of gonad" ;
rdfs:comment "A zone of skin part of some gonad." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0005156 .
obo:CL_4310129 a rdfs:Class ;
rdfs:label "STRd D1 Matrix MSN matrix D1 medium spiny neuron (Primate)" ;
rdfs:comment "A matrix D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D1 Matrix MSN." ;
rdfs:subClassOf obo:CL_4030043 , obo:CL_4310058 .
obo:GO_1905921 a rdfs:Class ;
rdfs:label "regulation of acetylcholine biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0060408 , obo:GO_0065007 .
obo:GO_0120033 a rdfs:Class ;
rdfs:label "negative regulation of plasma membrane bounded cell projection assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly." ;
rdfs:subClassOf obo:GO_0031345 , obo:GO_0065007 , obo:GO_0120032 .
obo:PATO_0002039 a rdfs:Class ;
rdfs:label "biconcave" ;
rdfs:comment "A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces." ;
rdfs:subClassOf obo:PATO_0001857 .
obo:GO_0095500 a rdfs:Class ;
rdfs:label "acetylcholine receptor signaling pathway" ;
rdfs:comment "The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands." ;
rdfs:subClassOf obo:GO_0007165 , obo:GO_0098926 .
obo:GO_0051983 a rdfs:Class ;
rdfs:label "regulation of chromosome segregation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ;
rdfs:subClassOf obo:GO_0010564 , obo:GO_0065007 .
obo:CHEBI_27955 a rdfs:Class ;
rdfs:label "streptamine" ;
rdfs:comment "An amino cyclitol consisting of scyllo-inositol with the hydroxy groups at positions 1 and 3 replaced by unsubstituted amino groups." ;
rdfs:subClassOf obo:CHEBI_61689 .
obo:GO_0071869 a rdfs:Class ;
rdfs:label "response to catecholamine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_0071867 , obo:GO_1901700 .
obo:PATO_0001404 a rdfs:Class ;
rdfs:label "nucleate quality" ;
rdfs:comment "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei." ;
rdfs:subClassOf obo:PATO_0001396 .
obo:GO_0051336 a rdfs:Class ;
rdfs:label "regulation of hydrolase activity" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." ;
rdfs:subClassOf obo:GO_0050790 , obo:GO_0065007 .
obo:PATO_0015006 a rdfs:Class ;
rdfs:label "polymeric" ;
rdfs:comment "A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:GO_0032963 a rdfs:Class ;
rdfs:label "collagen metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." ;
rdfs:subClassOf obo:GO_0008152 .
obo:CHEBI_23870 a rdfs:Class ;
rdfs:label "dodecyl group" ;
rdfs:subClassOf obo:CHEBI_22323 .
obo:CHEBI_76775 a rdfs:Class ;
rdfs:label "EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor" ;
rdfs:comment "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*)." ;
rdfs:subClassOf obo:CHEBI_76760 .
obo:CHEBI_83370 a rdfs:Class ;
rdfs:label "2,6-dimethyl-4-tetradecylmorpholine" ;
rdfs:comment "A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a tetradecyl group. The configuration at positions 2 and 6 is unknown or unspecified." ;
rdfs:subClassOf obo:CHEBI_38785 , obo:CHEBI_50996 .
obo:GO_0002578 a rdfs:Class ;
rdfs:label "negative regulation of antigen processing and presentation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002577 , obo:GO_0002683 , obo:GO_0065007 .
obo:PR_O54990 a rdfs:Class ;
rdfs:label "prominin-1 (mouse)" ;
rdfs:comment "A prominin-1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001786 , obo:PR_000029032 .
obo:CHEBI_60071 a rdfs:Class ;
rdfs:label "ertapenem(1-)" ;
rdfs:comment "The mono-anion resulting from the removal of a proton from one of the carboxyic acid groups of ertapenem." ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:GO_0000226 a rdfs:Class ;
rdfs:label "microtubule cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." ;
rdfs:subClassOf obo:GO_0007010 , obo:GO_0007017 , obo:GO_0016043 .
obo:UBERON_0035550 a rdfs:Class ;
rdfs:label "superficial vein" ;
rdfs:comment "Any of the veins carrying deoxygenated blood from the subcutaneous tissue layers." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:CL_4310144 a rdfs:Class ;
rdfs:label "VTR-HTH Glut glutamatergic neuron of the basal ganglia (Primate)" ;
rdfs:comment "A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the striatum, subthalamic nucleus, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:VTR-HTH Glut." ;
rdfs:subClassOf obo:CL_0000700 , obo:CL_4042040 .
obo:CL_4307106 a rdfs:Class ;
rdfs:label "MOL NN_4 Art3 mature myelinating oligodendrocyte (Mmus)" ;
rdfs:comment "A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Klk6 (Mmus), Dlc1 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Art3. These cells are located in the Medulla, Pons, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5286 MOL NN_4." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301614 .
obo:GO_0044237 a rdfs:Class ;
rdfs:label "obsolete cellular metabolic process" ;
rdfs:comment "OBSOLETE. The chemical reactions and pathways by which individual cells transform chemical substances." .
obo:PHIPO_0000988 a rdfs:Class ;
rdfs:label "obsolete altered protein level in a pathogen host interaction" ;
rdfs:comment "A cell phenotype in which the amount of protein measured in a pathogen or host cell differs from normal. Total protein or a specific protein may be affected." .
obo:PHIPO_0000676 a rdfs:Class ;
rdfs:label "resistance to nitrofurantoin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to nitrofurantoin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0032224 a rdfs:Class ;
rdfs:label "positive regulation of synaptic transmission, cholinergic" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ;
rdfs:subClassOf obo:GO_0032222 , obo:GO_0050806 , obo:GO_0065007 .
obo:CHEBI_38127 a rdfs:Class ;
rdfs:label "thiocarbamic ester" ;
rdfs:comment "Any organonitrogen compound with formula RS-C(=X)NH2 where X = O (monothiocarbamic esters) or S (dithiocarbamic esters), or their N-substituted derivatives." ;
rdfs:subClassOf obo:CHEBI_26959 , obo:CHEBI_35352 .
obo:GO_1901534 a rdfs:Class ;
rdfs:label "positive regulation of hematopoietic progenitor cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation." ;
rdfs:subClassOf obo:GO_0045597 , obo:GO_0065007 , obo:GO_1901532 .
obo:GO_0010894 a rdfs:Class ;
rdfs:label "negative regulation of steroid biosynthetic process" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ;
rdfs:subClassOf obo:GO_0045939 , obo:GO_0050810 , obo:GO_0051055 , obo:GO_0065007 .
obo:GO_0002730 a rdfs:Class ;
rdfs:label "regulation of dendritic cell cytokine production" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production." ;
rdfs:subClassOf obo:GO_0002703 , obo:GO_0002718 , obo:GO_0065007 .
obo:UBERON_0016855 a rdfs:Class ;
rdfs:label "ventral part of optic cup" ;
rdfs:comment "The ventral region of the optic cup that gives rise to the ventral part of the retina." ;
rdfs:subClassOf obo:UBERON_0000481 .
obo:GO_0050968 a rdfs:Class ;
rdfs:label "detection of chemical stimulus involved in sensory perception of pain" ;
rdfs:comment "The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0009593 , obo:GO_0050907 .
obo:UBERON_0010047 a rdfs:Class ;
rdfs:label "oral gland" ;
rdfs:comment "Gland of the epithelium lining the oral cavity. The most common are the salivary glands." ;
rdfs:subClassOf obo:UBERON_0002365 , obo:UBERON_0002530 , obo:UBERON_0003408 .
obo:GO_0016202 a rdfs:Class ;
rdfs:label "regulation of striated muscle tissue development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of striated muscle development." ;
rdfs:subClassOf obo:GO_0048634 , obo:GO_0065007 , obo:GO_1901861 .
obo:UBERON_0002329 a rdfs:Class ;
rdfs:label "somite" ;
rdfs:comment "Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm." ;
rdfs:subClassOf obo:UBERON_0005423 , obo:UBERON_0007503 .
obo:UBERON_0008886 a rdfs:Class ;
rdfs:label "pulmonary vascular system" ;
rdfs:comment "The part of the cardiovascular system consisting of all pulmonary arteries and all pulmonary veins." ;
rdfs:subClassOf obo:UBERON_0007798 .
obo:UBERON_0001769 a rdfs:Class ;
rdfs:label "iris" ;
rdfs:comment "The adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0004121 .
obo:CHEBI_18310 a rdfs:Class ;
rdfs:label "alkane" ;
rdfs:comment "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms." ;
rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_33653 .
obo:PR_P09581 a rdfs:Class ;
rdfs:label "macrophage colony-stimulating factor 1 receptor (mouse)" ;
rdfs:comment "A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000002062 , obo:PR_000029032 .
obo:GO_0044058 a rdfs:Class ;
rdfs:label "regulation of digestive system process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0044057 , obo:GO_0065007 .
obo:PR_000001968 a rdfs:Class ;
rdfs:label "tyrosine-protein phosphatase non-receptor type substrate 1" ;
rdfs:comment "A SIRP/SHPS-1 family protein that is a translation product of the human SIRPA gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:PR_000001832 .
obo:UBERON_0012082 a rdfs:Class ;
rdfs:label "bronchial lumen" ;
rdfs:comment "An anatomical cavity that is part of a bronchus." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:GO_0042462 a rdfs:Class ;
rdfs:label "eye photoreceptor cell development" ;
rdfs:comment "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0042461 .
obo:UBERON_0034933 a rdfs:Class ;
rdfs:label "layer of smooth muscle tissue" ;
rdfs:comment "Any organ component layer that consists of smooth muscle tissue." ;
rdfs:subClassOf obo:UBERON_0004923 , obo:UBERON_0018260 .
obo:UBERON_0004833 a rdfs:Class ;
rdfs:label "lip skeletal muscle" ;
rdfs:comment "A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001134 .
obo:UBERON_0003308 a rdfs:Class ;
rdfs:label "floor plate of telencephalon" ;
rdfs:comment "A floor plate that is part of a telencephalon [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0002616 , obo:UBERON_0003306 .
obo:CHEBI_79314 a rdfs:Class ;
rdfs:label "flame retardant" ;
rdfs:comment "Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:CHEBI_48422 a rdfs:Class ;
rdfs:label "angiogenesis inhibitor" ;
rdfs:comment "An agent and endogenous substances that antagonize or inhibit the development of new blood vessels." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:UBERON_0010364 a rdfs:Class ;
rdfs:label "dermal skeleton" ;
rdfs:comment "Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements." ;
rdfs:subClassOf obo:UBERON_0010912 .
obo:CHEBI_161680 a rdfs:Class ;
rdfs:label "aztreonam" ;
rdfs:comment "A synthetic monocyclic β-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking." ;
rdfs:subClassOf obo:CHEBI_50695 , obo:CHEBI_88225 .
obo:GO_0099571 a rdfs:Class ;
rdfs:label "postsynaptic cytoskeleton" ;
rdfs:comment "The portion of the cytoskeleton contained within the postsynapse." ;
rdfs:subClassOf obo:GO_0005856 .
obo:UBERON_0004664 a rdfs:Class ;
rdfs:label "aorta tunica adventitia" ;
rdfs:comment "The outermost layer of the aorta wall, containing connective tissue and collagen and elastic fibers." ;
rdfs:subClassOf obo:UBERON_0005734 .
obo:GO_0061982 a rdfs:Class ;
rdfs:label "meiosis I cell cycle process" ;
rdfs:comment "A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs." ;
rdfs:subClassOf obo:GO_1903046 .
obo:GO_1905322 a rdfs:Class ;
rdfs:label "positive regulation of mesenchymal stem cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration." ;
rdfs:subClassOf obo:GO_0030335 , obo:GO_0065007 , obo:GO_1905320 .
obo:CHEBI_64130 a rdfs:Class ;
rdfs:label "pyrazinoindole" ;
rdfs:comment "An organic heterotricyclic compound comprising a pyrazine ring fused to an indole ring system." ;
rdfs:subClassOf obo:CHEBI_38101 .
obo:GO_0004930 a rdfs:Class ;
rdfs:label "G protein-coupled receptor activity" ;
rdfs:comment "Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." ;
rdfs:subClassOf obo:GO_0004888 .
obo:UBERON_0004756 a rdfs:Class ;
rdfs:label "dermal skeletal element" ;
rdfs:comment "Dermis-derived entity that is made of skeletal tissue." ;
rdfs:subClassOf obo:UBERON_0004765 .
obo:PHIPO_0000929 a rdfs:Class ;
rdfs:label "abnormal cellular process"@en ;
rdfs:comment "A phenotype in which a specific cellular process is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000930 .
obo:PHIPO_0000583 a rdfs:Class ;
rdfs:label "resistance to antimycin A"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to antimycin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0007811 a rdfs:Class ;
rdfs:label "craniocervical region" ;
rdfs:comment "The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae." ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:UBERON_0010314 a rdfs:Class ;
rdfs:label "structure with developmental contribution from neural crest" ;
rdfs:comment "An anatomical structure that has some part that develops from the neural crest." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:UBERON_0001785 a rdfs:Class ;
rdfs:label "cranial nerve" ;
rdfs:comment "Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord." ;
rdfs:subClassOf obo:UBERON_0001021 , obo:UBERON_0011779 , obo:UBERON_0034713 .
obo:CL_0000439 a rdfs:Class ;
rdfs:label "prolactin secreting cell" ;
rdfs:comment "A peptide hormone cell that secretes prolactin." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000154 , obo:CL_0000167 .
obo:UBERON_0011595 a rdfs:Class ;
rdfs:label "jaw region" ;
rdfs:comment "A subdivision of the head that corresponds to the jaw skeleton, containing both soft tissue, skeleton and teeth (when present). The jaw region is divided into upper and lower regions." ;
rdfs:subClassOf obo:UBERON_0000475 , obo:UBERON_0010314 .
obo:GO_0110116 a rdfs:Class ;
rdfs:label "regulation of compound eye photoreceptor cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation." ;
rdfs:subClassOf obo:GO_0046532 , obo:GO_0065007 .
obo:PHIPO_0001200 a rdfs:Class ;
rdfs:label "disease present"@en ;
rdfs:comment "A pathogen host interaction phenotype where disease is present." ;
rdfs:subClassOf obo:PHIPO_0001198 .
obo:GO_0036072 a rdfs:Class ;
rdfs:label "direct ossification" ;
rdfs:comment "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues." ;
rdfs:subClassOf obo:GO_0001503 .
obo:UBERON_0004145 a rdfs:Class ;
rdfs:label "outflow tract" ;
rdfs:comment "The outflow tract is the portion of the heart through which blood flows into the arteries." ;
rdfs:subClassOf obo:UBERON_0004111 .
obo:NCBITaxon_28009 a rdfs:Class ;
rdfs:label "Choanoflagellata" ;
rdfs:subClassOf obo:NCBITaxon_33154 .
obo:GO_0016482 a rdfs:Class ;
rdfs:label "cytosolic transport" ;
rdfs:comment "The directed movement of substances or organelles within the cytosol." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0046907 .
obo:GO_0061537 a rdfs:Class ;
rdfs:label "glycine secretion, neurotransmission" ;
rdfs:comment "The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0007269 , obo:GO_0061536 .
obo:PR_P61148 a rdfs:Class ;
rdfs:label "fibroblast growth factor 1 (mouse)" ;
rdfs:comment "A fibroblast growth factor 1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000007479 , obo:PR_000029032 .
obo:GO_0048821 a rdfs:Class ;
rdfs:label "erythrocyte development" ;
rdfs:comment "The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0061515 .
obo:PR_000001094 a rdfs:Class ;
rdfs:label "rhodopsin-like G-protein coupled receptor" ;
rdfs:comment "A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions." ;
rdfs:subClassOf obo:PR_000030035 .
obo:CHEBI_30879 a rdfs:Class ;
rdfs:label "alcohol" ;
rdfs:comment "A compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom." ;
rdfs:subClassOf obo:CHEBI_33822 .
obo:GO_0070345 a rdfs:Class ;
rdfs:label "negative regulation of fat cell proliferation" ;
rdfs:comment "Any process that stops or decreases the rate or extent of fat cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0065007 , obo:GO_0070344 .
obo:GO_0043231 a rdfs:Class ;
rdfs:label "intracellular membrane-bounded organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0043227 , obo:GO_0043229 .
obo:PHIPO_0000282 a rdfs:Class ;
rdfs:label "obsolete abnormal stature" .
obo:CL_4300370 a rdfs:Class ;
rdfs:label "VLMC NN vascular leptomeningeal cell (Mmus)" ;
rdfs:comment "A vascular leptomeningeal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Slc6a13 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:330 VLMC NN." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4023051 .
obo:CHEBI_33579 a rdfs:Class ;
rdfs:label "main group molecular entity" ;
rdfs:comment "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:CL_0008059 a rdfs:Class ;
rdfs:label "GABA-Gly neuron" ;
rdfs:comment "A neuron that releases both gamma-aminobutyric acid and glycine as vesicular neurotransmitters. Examples include types of amacrine cell and types of cerebellar inhibitory neurons." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_0000617 , obo:CL_1001509 .
obo:UBERON_0004265 a rdfs:Class ;
rdfs:label "outflow tract myocardium" ;
rdfs:comment "A myocardium that is part of a outflow tract [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002349 .
obo:GO_0055025 a rdfs:Class ;
rdfs:label "positive regulation of cardiac muscle tissue development" ;
rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development." ;
rdfs:subClassOf obo:GO_0045844 , obo:GO_0055024 , obo:GO_0065007 .
obo:PHIPO_0000182 a rdfs:Class ;
rdfs:label "absence of host-defense induced lesion by host hypersensitive response"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense, is absent." ;
rdfs:subClassOf obo:PHIPO_0000481 .
obo:CHEBI_38012 a rdfs:Class ;
rdfs:label "aminoglycoside sulfate salt" ;
rdfs:subClassOf obo:CHEBI_37852 .
obo:GO_0042997 a rdfs:Class ;
rdfs:label "negative regulation of Golgi to plasma membrane protein transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." ;
rdfs:subClassOf obo:GO_0042996 , obo:GO_0051224 , obo:GO_0065007 , obo:GO_1903077 .
obo:PHIPO_0000173 a rdfs:Class ;
rdfs:label "abolished filamentous growth on host surface"@en ;
rdfs:comment "A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is abolished (it was present and is now absent)." ;
rdfs:subClassOf obo:PHIPO_0000350 .
obo:CL_4307066 a rdfs:Class ;
rdfs:label "Tanycyte NN_2 Mroh5 alpha1-tanycyte (Mmus)" ;
rdfs:comment "A alpha1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ccdc170 (Mmus), Nkx2-4 (Mmus), Dock8 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Mroh5. These cells are located in the Hypothalamus, brain , in or close to the regions: Periventricular hypothalamic nucleus, intermediate part, third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5246 Tanycyte NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4042017 , obo:CL_4301603 .
obo:GO_0045686 a rdfs:Class ;
rdfs:label "negative regulation of glial cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation." ;
rdfs:subClassOf obo:GO_0014014 , obo:GO_0045685 , obo:GO_0065007 .
obo:UBERON_0006984 a rdfs:Class ;
rdfs:label "anatomical surface" ;
rdfs:comment "A two dimensional anatomical structure that is the boundary between an anatomical structure and an anatomical substance, an anatomical space or the organism's environment. Examples include the surface of your skin, the surface of the lining of your gut; the surface of the endothelium of you aorta that is in contact with blood.n." ;
rdfs:subClassOf obo:UBERON_0010199 .
obo:GO_1904749 a rdfs:Class ;
rdfs:label "regulation of protein localization to nucleolus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to nucleolus." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900180 .
obo:BFO_0000003 a rdfs:Class ;
rdfs:label "occurrent"@en ;
rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
rdfs:subClassOf obo:BFO_0000001 .
obo:PATO_0070046 a rdfs:Class ;
rdfs:label "neutrophillic" ;
rdfs:comment "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain." ;
rdfs:subClassOf obo:PATO_0070045 .
obo:CHEBI_38582 a rdfs:Class ;
rdfs:label "difluorobenzene" ;
rdfs:comment "Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying two fluorine atoms." ;
rdfs:subClassOf obo:CHEBI_35496 .
obo:UBERON_0002203 a rdfs:Class ;
rdfs:label "vasculature of eye" ;
rdfs:comment "Vasculature that is part of the eye region." ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0002200 , obo:UBERON_0006876 .
obo:GO_0014048 a rdfs:Class ;
rdfs:label "regulation of glutamate secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the controlled release of glutamate." ;
rdfs:subClassOf obo:GO_0032890 , obo:GO_0051955 , obo:GO_0065007 , obo:GO_1903530 .
obo:PHIPO_0000575 a rdfs:Class ;
rdfs:label "resistance to micafungin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to micafungin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_33250 a rdfs:Class ;
rdfs:label "atom" ;
rdfs:comment "A chemical entity constituting the smallest component of an element having the chemical properties of the element." ;
rdfs:subClassOf obo:CHEBI_24431 .
obo:GO_0061560 a rdfs:Class ;
rdfs:label "cranial ganglion formation" ;
rdfs:comment "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0048646 , obo:GO_0061554 .
obo:NCBITaxon_50557 a rdfs:Class ;
rdfs:label "Insecta" ;
rdfs:subClassOf obo:NCBITaxon_6960 .
obo:UBERON_0003084 a rdfs:Class ;
rdfs:label "heart primordium" ;
rdfs:comment "Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone." ;
rdfs:subClassOf obo:UBERON_0001048 .
obo:PR_P50114 a rdfs:Class ;
rdfs:label "protein S100-B (mouse)" ;
rdfs:comment "A protein S100-B that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000014419 , obo:PR_000029032 .
obo:GO_0003371 a rdfs:Class ;
rdfs:label "establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration" ;
rdfs:comment "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell." ;
rdfs:subClassOf obo:GO_0030952 .
obo:UBERON_0001835 a rdfs:Class ;
rdfs:label "lower lip" ;
rdfs:comment "Lip that covers the lower portion of the mouth.[TAO]." ;
rdfs:subClassOf obo:UBERON_0001833 .
obo:CL_0002573 a rdfs:Class ;
rdfs:label "Schwann cell" ;
rdfs:comment "A glial cell that myelinates or ensheathes axons in the peripheral nervous system." ;
rdfs:subClassOf obo:CL_0000125 .
obo:PHIPO_0000439 a rdfs:Class ;
rdfs:label "pathogen reproductive phenotype within host"@en ;
rdfs:comment "A pathogen host interaction phenotype which affects the pathogen reproductive process within the host. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003)." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:CL_4301589 a rdfs:Class ;
rdfs:label "Astro-NT NN_1 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Lhfpl3 (Mmus), Gria1 (Mmus), Hopx (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1159 Astro-NT NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300358 .
obo:CHEBI_23213 a rdfs:Class ;
rdfs:label "choline ester" ;
rdfs:subClassOf obo:CHEBI_35701 .
obo:CHEBI_41609 a rdfs:Class ;
rdfs:label "carbonate" ;
rdfs:subClassOf obo:CHEBI_35604 .
obo:GO_0031727 a rdfs:Class ;
rdfs:label "CCR2 chemokine receptor binding" ;
rdfs:comment "Binding to a CCR2 chemokine receptor." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0048020 .
obo:CHEBI_30089 a rdfs:Class ;
rdfs:label "acetate" ;
rdfs:comment "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:CHEBI_9242 a rdfs:Class ;
rdfs:label "spiroxamine" ;
rdfs:comment "The spiroketal resulting from the formal condensation of 4-tert-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powdery mildew in the production of cereals, bananas and grapes." ;
rdfs:subClassOf obo:CHEBI_39430 , obo:CHEBI_50996 , obo:CHEBI_72600 .
obo:UBERON_0001875 a rdfs:Class ;
rdfs:label "globus pallidus" ;
rdfs:comment "Subcortical nucleus, functionally part of the basal ganglia, which consists of two segments the external (or lateral) and internal (or medial) separated by the medial medullary lamina in primates. In rodents, The globus pallidus lateral is separated from the medial segment by the fibers of the internal capsule/cerebral peduncle." ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0009663 .
obo:RO_0002225 a rdf:Property ;
rdfs:label "develops from part of"@en ;
rdfs:comment "x develops from part of y if and only if there exists some z such that x develops from z and z is part of y" ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000004 ;
rdfs:subPropertyOf obo:RO_0002202 .
obo:GO_0002719 a rdfs:Class ;
rdfs:label "negative regulation of cytokine production involved in immune response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response." ;
rdfs:subClassOf obo:GO_0001818 , obo:GO_0002701 , obo:GO_0002718 , obo:GO_0065007 .
obo:CL_4307091 a rdfs:Class ;
rdfs:label "OPC NN_2 oligodendrocyte precursor cell (Mmus)" ;
rdfs:comment "A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Cenpf (Mmus), Cenpa (Mmus). It is distinguished from other OPC NN cells by expression of Cenpa. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5271 OPC NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300366 .
obo:CHEBI_33709 a rdfs:Class ;
rdfs:label "amino acid" ;
rdfs:comment "A carboxylic acid containing one or more amino groups." ;
rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_50047 .
obo:PHIPO_0001369 a rdfs:Class ;
rdfs:label "increased rate of hyphae formation"@en ;
rdfs:comment "An individual organism growth phenotype in which the rate, or speed, of hyphae formation is increased." ;
rdfs:subClassOf obo:PHIPO_0001234 .
obo:UBERON_0014794 a rdfs:Class ;
rdfs:label "pectoral appendage muscle" ;
rdfs:comment "Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin)." ;
rdfs:subClassOf obo:UBERON_0010891 , obo:UBERON_0014892 .
obo:GO_0051645 a rdfs:Class ;
rdfs:label "Golgi localization" ;
rdfs:comment "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051640 .
obo:GO_0032941 a rdfs:Class ;
rdfs:label "secretion by tissue" ;
rdfs:comment "The controlled release of a substance by a tissue." ;
rdfs:subClassOf obo:GO_0032501 , obo:GO_0046903 .
obo:GO_0051701 a rdfs:Class ;
rdfs:label "biological process involved in interaction with host" ;
rdfs:comment "An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism." ;
rdfs:subClassOf obo:GO_0044403 .
obo:CL_0009004 a rdfs:Class ;
rdfs:label "retinal cell" ;
rdfs:comment "Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." ;
rdfs:subClassOf obo:CL_0002319 .
obo:UBERON_0002400 a rdfs:Class ;
rdfs:label "parietal pleura" ;
rdfs:comment "The outer serous membrane of the pulmonary pleural." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:GO_0005740 a rdfs:Class ;
rdfs:label "mitochondrial envelope" ;
rdfs:comment "The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space." ;
rdfs:subClassOf obo:GO_0031967 .
obo:CHEBI_26649 a rdfs:Class ;
rdfs:label "serine derivative" ;
rdfs:comment "An amino acid derivative resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of serine by a heteroatom. The definition normally excludes peptides containing serine residues." ;
rdfs:subClassOf obo:CHEBI_83821 .
obo:GO_0014009 a rdfs:Class ;
rdfs:label "glial cell proliferation" ;
rdfs:comment "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others." ;
rdfs:subClassOf obo:GO_0008283 .
obo:GO_0032975 a rdfs:Class ;
rdfs:label "amino acid transmembrane import into vacuole" ;
rdfs:comment "The directed movement of amino acids into the vacuole across the vacuolar membrane." ;
rdfs:subClassOf obo:GO_0003333 , obo:GO_0010496 , obo:GO_0034486 , obo:GO_0055085 .
obo:GO_1905632 a rdfs:Class ;
rdfs:label "protein localization to euchromatin" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, a location within an euchromatin." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0071168 .
obo:UBERON_0036285 a rdfs:Class ;
rdfs:label "wall of left ventricle" ;
rdfs:comment "Wall of ventricle which is continuous with the wall of aorta." ;
rdfs:subClassOf obo:UBERON_0004784 .
obo:PATO_0000694 a rdfs:Class ;
rdfs:label "premature" ;
rdfs:comment "A quality of a process which starts earlier than the natural start time or the reference process." ;
rdfs:subClassOf obo:PATO_0002325 .
obo:GO_0140250 a rdfs:Class ;
rdfs:label "regulation protein catabolic process at synapse" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0065007 .
obo:UBERON_0003937 a rdfs:Class ;
rdfs:label "reproductive gland" ;
rdfs:comment "Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction." ;
rdfs:subClassOf obo:UBERON_0002530 , obo:UBERON_0005156 .
obo:GO_0031346 a rdfs:Class ;
rdfs:label "positive regulation of cell projection organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ;
rdfs:subClassOf obo:GO_0031344 , obo:GO_0051130 , obo:GO_0065007 .
obo:GO_0021783 a rdfs:Class ;
rdfs:label "preganglionic parasympathetic fiber development" ;
rdfs:comment "The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:GO_0140097 a rdfs:Class ;
rdfs:label "catalytic activity, acting on DNA" ;
rdfs:comment "Catalytic activity that acts to modify DNA." ;
rdfs:subClassOf obo:GO_0003824 , obo:GO_0140640 .
obo:GO_0072597 a rdfs:Class ;
rdfs:label "maintenance of protein location in chloroplast" ;
rdfs:comment "Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0045185 , obo:GO_0072595 .
obo:GO_2001233 a rdfs:Class ;
rdfs:label "regulation of apoptotic signaling pathway" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway." ;
rdfs:subClassOf obo:GO_0009966 , obo:GO_0042981 , obo:GO_0065007 .
obo:UBERON_0011676 a rdfs:Class ;
rdfs:label "subdivision of organism along main body axis" ;
rdfs:comment "A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column." ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:GO_0007076 a rdfs:Class ;
rdfs:label "mitotic chromosome condensation" ;
rdfs:comment "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." ;
rdfs:subClassOf obo:GO_0030261 , obo:GO_1903047 .
obo:UBERON_0018674 a rdfs:Class ;
rdfs:label "heart vasculature" ;
rdfs:comment "An interconnected tubular multi-tissue structure that contains fluid that is actively transported around the heart." ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0002201 , obo:UBERON_0006876 .
obo:UBERON_0006598 a rdfs:Class ;
rdfs:label "presumptive structure" ;
rdfs:comment "Portion of embryonic tissue determined by fate mapping to become a structure." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005423 .
obo:GO_0014895 a rdfs:Class ;
rdfs:label "smooth muscle hypertrophy" ;
rdfs:comment "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy." ;
rdfs:subClassOf obo:GO_0014805 , obo:GO_0014896 .
obo:GO_0035262 a rdfs:Class ;
rdfs:label "gonad morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0009653 , obo:GO_0009887 .
obo:CL_0000837 a rdfs:Class ;
rdfs:label "hematopoietic multipotent progenitor cell" ;
rdfs:comment "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0000988 , obo:CL_0008001 .
obo:CHEBI_35473 a rdfs:Class ;
rdfs:label "tranquilizing drug" ;
rdfs:comment "A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour." ;
rdfs:subClassOf obo:CHEBI_35471 , obo:CHEBI_35488 .
obo:GO_0045671 a rdfs:Class ;
rdfs:label "negative regulation of osteoclast differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation." ;
rdfs:subClassOf obo:GO_0002762 , obo:GO_0045670 , obo:GO_0065007 .
obo:PHIPO_0000938 a rdfs:Class ;
rdfs:label "vegetative cell lysis"@en ;
rdfs:comment "An single species phenotype in which a vegetative cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost." ;
rdfs:subClassOf obo:PHIPO_0000936 .
obo:UBERON_0004456 a rdfs:Class ;
rdfs:label "entire sense organ system" ;
rdfs:comment "Sum of all sensory systems in an organism." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:PHIPO_0000992 a rdfs:Class ;
rdfs:label "increased expression of a host defense-related protein involved in a pathogen interaction"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host defense-related protein usually present during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0000991 .
obo:CHEBI_38497 a rdfs:Class ;
rdfs:label "respiratory-chain inhibitor" ;
rdfs:subClassOf obo:CHEBI_38496 .
obo:GO_1901201 a rdfs:Class ;
rdfs:label "regulation of extracellular matrix assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of extracellular matrix assembly." ;
rdfs:subClassOf obo:GO_0044087 , obo:GO_0065007 , obo:GO_1903053 .
obo:CHEBI_50994 a rdfs:Class ;
rdfs:label "primary amino compound" ;
rdfs:comment "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:GO_0015698 a rdfs:Class ;
rdfs:label "inorganic anion transport" ;
rdfs:comment "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." ;
rdfs:subClassOf obo:GO_0006810 .
obo:CHEBI_86323 a rdfs:Class ;
rdfs:label "conazole antifungal agent" ;
rdfs:comment "A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function." ;
rdfs:subClassOf obo:CHEBI_68452 .
obo:GO_0007605 a rdfs:Class ;
rdfs:label "sensory perception of sound" ;
rdfs:comment "The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound." ;
rdfs:subClassOf obo:GO_0050954 .
obo:CHEBI_22944 a rdfs:Class ;
rdfs:label "butanediols" ;
rdfs:comment "A diol that is a butanediol or a derivative of a butanediol." ;
rdfs:subClassOf obo:CHEBI_23824 .
obo:GO_0099577 a rdfs:Class ;
rdfs:label "regulation of translation at presynapse, modulating synaptic transmission" ;
rdfs:comment "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0099171 , obo:GO_0099547 , obo:GO_0140244 .
obo:CL_0000680 a rdfs:Class ;
rdfs:label "muscle precursor cell" ;
rdfs:comment "A non-terminally differentiated cell that is capable of developing into a muscle cell." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0011026 , obo:CL_0011115 .
obo:PR_Q9CXM0 a rdfs:Class ;
rdfs:label "chondrolectin (mouse)" ;
rdfs:comment "A chondrolectin that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000005444 , obo:PR_000029032 .
obo:GO_0051055 a rdfs:Class ;
rdfs:label "negative regulation of lipid biosynthetic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0045833 , obo:GO_0046890 , obo:GO_0065007 .
obo:GO_2000383 a rdfs:Class ;
rdfs:label "regulation of ectoderm development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of ectoderm development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0001819 a rdfs:Class ;
rdfs:label "positive regulation of cytokine production" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of production of a cytokine." ;
rdfs:subClassOf obo:GO_0001817 , obo:GO_0010628 , obo:GO_0051240 , obo:GO_0065007 .
obo:CHEBI_23007 a rdfs:Class ;
rdfs:label "carbohydrate-containing antibiotic" ;
rdfs:comment "Any carbohydrate derivative that exhibits antibiotic activity." ;
rdfs:subClassOf obo:CHEBI_63299 .
obo:GO_0007134 a rdfs:Class ;
rdfs:label "meiotic telophase I" ;
rdfs:comment "The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." ;
rdfs:subClassOf obo:GO_0051326 , obo:GO_0098764 .
obo:GO_0097048 a rdfs:Class ;
rdfs:label "dendritic cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0071887 .
obo:GO_0007018 a rdfs:Class ;
rdfs:label "microtubule-based movement" ;
rdfs:comment "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." ;
rdfs:subClassOf obo:GO_0007017 .
obo:OGMS_0000045 a rdfs:Class ;
rdfs:label "disorder" ;
rdfs:comment "A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease."@en ;
rdfs:subClassOf obo:BFO_0000040 .
obo:CHEBI_25529 a rdfs:Class ;
rdfs:label "pyridinecarboxamide" ;
rdfs:comment "A member of the class of pyridines that is a substituted pyridine in which at least one of the substituents is a carboxamide or N-substituted caraboxamide group." ;
rdfs:subClassOf obo:CHEBI_26421 , obo:CHEBI_37622 .
obo:UBERON_0001016 a rdfs:Class ;
rdfs:label "nervous system" ;
rdfs:comment "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." ;
rdfs:subClassOf obo:UBERON_0000467 .
obo:GO_0060952 a rdfs:Class ;
rdfs:label "cardiac glial cell development" ;
rdfs:comment "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell." ;
rdfs:subClassOf obo:GO_0021782 , obo:GO_0048468 , obo:GO_0055006 .
obo:CHEBI_10023 a rdfs:Class ;
rdfs:label "voriconazole" ;
rdfs:comment "A triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp. It is an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4." ;
rdfs:subClassOf obo:CHEBI_26878 , obo:CHEBI_38582 , obo:CHEBI_38976 , obo:CHEBI_39447 , obo:CHEBI_87071 , obo:CHEBI_87101 .
obo:PATO_0001547 a rdfs:Class ;
rdfs:label "quality of a gas" ;
rdfs:comment "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape." ;
rdfs:subClassOf obo:PATO_0002198 .
obo:GO_0045989 a rdfs:Class ;
rdfs:label "positive regulation of striated muscle contraction" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of striated muscle contraction." ;
rdfs:subClassOf obo:GO_0006942 , obo:GO_0045933 , obo:GO_0065007 .
obo:PHIPO_0001290 a rdfs:Class ;
rdfs:label "normal growth on azoxystrobin"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to azoxystrobin (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_16991 a rdfs:Class .
obo:CHEBI_16313 a rdfs:Class ;
rdfs:label "D-proline" ;
rdfs:comment "The D-enantiomer of proline." ;
rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_26271 .
obo:GO_0050941 a rdfs:Class ;
rdfs:label "negative regulation of pigment cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0048086 , obo:GO_0050932 , obo:GO_0065007 .
obo:GO_0032277 a rdfs:Class ;
rdfs:label "negative regulation of gonadotropin secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin." ;
rdfs:subClassOf obo:GO_0032276 , obo:GO_0046888 , obo:GO_0051241 , obo:GO_0065007 .
obo:UBERON_0016522 a rdfs:Class ;
rdfs:label "cavity of right atrium" ;
rdfs:comment "Luminal space of the right atrium of the heart." ;
rdfs:subClassOf obo:UBERON_0002553 , obo:UBERON_0035763 .
obo:GO_0060412 a rdfs:Class ;
rdfs:label "ventricular septum morphogenesis" ;
rdfs:comment "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060411 .
obo:CHEBI_23089 a rdfs:Class ;
rdfs:label "chelate-forming peptide" ;
rdfs:subClassOf obo:CHEBI_25903 .
obo:CHEBI_72587 a rdfs:Class .
obo:CL_4310130 a rdfs:Class ;
rdfs:label "STRd D1 Striosome MSN striosomal D1 medium spiny neuron (Primate)" ;
rdfs:comment "A striosomal D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D1 Striosome MSN." ;
rdfs:subClassOf obo:CL_4030048 , obo:CL_4310058 .
obo:GO_2000175 a rdfs:Class ;
rdfs:label "negative regulation of pro-T cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation." ;
rdfs:subClassOf obo:GO_0045581 , obo:GO_0065007 , obo:GO_1905457 , obo:GO_2000174 .
obo:UBERON_0013156 a rdfs:Class ;
rdfs:label "1st arch mandibular endoderm" ;
rdfs:subClassOf obo:UBERON_0003258 , obo:UBERON_0005291 .
obo:GO_0072384 a rdfs:Class ;
rdfs:label "organelle transport along microtubule" ;
rdfs:comment "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." ;
rdfs:subClassOf obo:GO_0010970 , obo:GO_0046907 , obo:GO_0051656 .
obo:CL_0000526 a rdfs:Class ;
rdfs:label "afferent neuron" ;
rdfs:comment "A neuron which conveys sensory information centrally from the periphery." ;
rdfs:subClassOf obo:CL_0000540 .
obo:UBERON_0006331 a rdfs:Class ;
rdfs:label "brainstem nucleus" ;
rdfs:comment "A nucleus of brain that is part of a brainstem." ;
rdfs:subClassOf obo:UBERON_0002308 .
obo:GO_0140318 a rdfs:Class ;
rdfs:label "protein transporter activity" ;
rdfs:comment "Directly binding to a specific protein and delivering it to a specific cellular location." ;
rdfs:subClassOf obo:GO_0005215 .
obo:GO_0019953 a rdfs:Class ;
rdfs:label "sexual reproduction" ;
rdfs:comment "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." ;
rdfs:subClassOf obo:GO_0022414 .
obo:CHEBI_17234 a rdfs:Class ;
rdfs:label "glucose" ;
rdfs:comment "An aldohexose used as a source of energy and metabolic intermediate." ;
rdfs:subClassOf obo:CHEBI_33917 .
obo:GO_0043362 a rdfs:Class ;
rdfs:label "nucleate erythrocyte maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0043249 .
obo:CHEBI_48854 a rdfs:Class ;
rdfs:label "sulfurous acid" ;
rdfs:subClassOf obo:CHEBI_33402 .
obo:PHIPO_0001301 a rdfs:Class ;
rdfs:label "resistance to pyrrolnitrin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to pyrrolnitrin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_4023057 a rdfs:Class ;
rdfs:label "cerebellar inhibitory GABAergic interneuron" ;
rdfs:comment "A GABAergic interneuron whose soma is located in the cerebellar cortex." ;
rdfs:subClassOf obo:CL_0011005 , obo:CL_1001611 .
obo:UBERON_0013685 a rdfs:Class ;
rdfs:label "foramen of skull" ;
rdfs:comment "Anatomical space that is an opening in a bone of the skull." ;
rdfs:subClassOf obo:UBERON_0005744 .
obo:GO_0005737 a rdfs:Class ;
rdfs:label "cytoplasm" ;
rdfs:comment "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0006893 a rdfs:Class ;
rdfs:label "Golgi to plasma membrane transport" ;
rdfs:comment "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. Golgi to plasma membrane transport precedes exocytosis." ;
rdfs:subClassOf obo:GO_0006892 , obo:GO_0016192 , obo:GO_0098876 .
obo:UBERON_0010303 a rdfs:Class ;
rdfs:label "extraembryonic epithelium" ;
rdfs:comment "An epithelium that is part of a extraembryonic structure." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0005292 .
obo:GO_0071953 a rdfs:Class ;
rdfs:label "elastic fiber" ;
rdfs:comment "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." ;
rdfs:subClassOf obo:GO_0099512 .
obo:UBERON_0010498 a rdfs:Class ;
rdfs:label "pseudostratified columnar epithelium" ;
rdfs:comment "A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels." ;
rdfs:subClassOf obo:UBERON_0000485 .
obo:GO_0007308 a rdfs:Class ;
rdfs:label "oocyte construction" ;
rdfs:comment "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0032502 , obo:GO_0048469 .
obo:PHIPO_0000171 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host interaction RNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." .
obo:GO_0007027 a rdfs:Class ;
rdfs:label "negative regulation of axonemal microtubule depolymerization" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." ;
rdfs:subClassOf obo:GO_0007026 , obo:GO_0010937 , obo:GO_0031345 , obo:GO_0065007 , obo:GO_0120035 .
obo:CHEBI_52090 a rdfs:Class ;
rdfs:label "methoxide" ;
rdfs:comment "An organic anion that is the conjugate base of methanol." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:CL_0000287 a rdfs:Class ;
rdfs:label "eye photoreceptor cell" ;
rdfs:comment "Any photoreceptor cell that is part of some eye." ;
rdfs:subClassOf obo:CL_0000006 , obo:CL_0000210 .
obo:GO_0009507 a rdfs:Class ;
rdfs:label "chloroplast" ;
rdfs:comment "A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma." ;
rdfs:subClassOf obo:GO_0009536 .
obo:PHIPO_0000646 a rdfs:Class ;
rdfs:label "resistance to fenhexamid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fenhexamid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0030886 a rdfs:Class ;
rdfs:label "negative regulation of myeloid dendritic cell activation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation." ;
rdfs:subClassOf obo:GO_0002695 , obo:GO_0030885 , obo:GO_0065007 .
obo:PHIPO_0000697 a rdfs:Class ;
rdfs:label "resistance to fosfomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fosfomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:NCBITaxon_33213 a rdfs:Class ;
rdfs:label "Bilateria" ;
rdfs:subClassOf obo:NCBITaxon_6072 .
a rdfs:Class ;
rdfs:label "Cerebrum" ;
rdfs:subClassOf , obo:UBERON_0001893 .
obo:UBERON_0019293 a rdfs:Class ;
rdfs:label "white matter of pontine tegmentum" ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0019292 .
obo:GO_0005277 a rdfs:Class ;
rdfs:label "acetylcholine transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." ;
rdfs:subClassOf obo:GO_0005326 , obo:GO_0022857 , obo:GO_1901375 .
obo:GO_1904777 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to cell cortex" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904376 , obo:GO_1904776 .
obo:GO_1904375 a rdfs:Class ;
rdfs:label "regulation of protein localization to cell periphery" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to cell periphery." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:PHIPO_0000326 a rdfs:Class ;
rdfs:label "obsolete loss of effector of pathogenicity suppression of host defense" ;
rdfs:comment "The pathogen effector entity has lost the ability to suppress host defense." .
obo:UBERON_0004716 a rdfs:Class ;
rdfs:label "conceptus" ;
rdfs:comment "The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:CL_0000352 a rdfs:Class ;
rdfs:label "epiblast cell" ;
rdfs:comment "A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation." ;
rdfs:subClassOf obo:CL_0000052 .
obo:GO_0001956 a rdfs:Class ;
rdfs:label "positive regulation of neurotransmitter secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." ;
rdfs:subClassOf obo:GO_0046928 , obo:GO_0050806 , obo:GO_0051590 , obo:GO_0065007 , obo:GO_1903532 .
obo:GO_1903729 a rdfs:Class ;
rdfs:label "regulation of plasma membrane organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of plasma membrane organization." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:CHEBI_59835 a rdfs:Class ;
rdfs:label "hydroxy fatty acid anion" ;
rdfs:comment "The conjugate base of any hydroxy fatty acid, formed by deprotonation of the carboxylic acid moiety." ;
rdfs:subClassOf obo:CHEBI_28868 , obo:CHEBI_36059 .
obo:UBERON_0003932 a rdfs:Class ;
rdfs:label "cartilage element of chondrocranium" ;
rdfs:comment "A cartilage element of chondrocranium. Example: neurocranial trabecula." ;
rdfs:subClassOf obo:UBERON_0003933 , obo:UBERON_0007844 .
obo:GO_0021884 a rdfs:Class ;
rdfs:label "forebrain neuron development" ;
rdfs:comment "The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0021954 , obo:GO_0048468 .
obo:UBERON_0014542 a rdfs:Class ;
rdfs:label "cervical division of cord spinal central canal" ;
rdfs:comment "Part of central canal contained within the cervical spinal cord. It is continuous caudally with the thoracic spinal cord central canal and rostrally with the fourth ventricle of the brain via the obex." ;
rdfs:subClassOf obo:UBERON_0014538 .
obo:CHEBI_24852 a rdfs:Class ;
rdfs:label "insecticide" ;
rdfs:comment "Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects." ;
rdfs:subClassOf obo:CHEBI_25944 .
obo:CHEBI_9763 a rdfs:Class ;
rdfs:label "trovafloxacin" ;
rdfs:comment "A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 6-amino-3-azabicyclo[3.1.0]hex-3-yl substituents at positions 1, 6 and 7 respectively. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure." ;
rdfs:subClassOf obo:CHEBI_23765 , obo:CHEBI_25384 , obo:CHEBI_33709 , obo:CHEBI_38295 , obo:CHEBI_38582 , obo:CHEBI_50994 , obo:CHEBI_50996 , obo:CHEBI_73537 , obo:CHEBI_86324 , obo:CHEBI_87211 .
obo:GO_0061050 a rdfs:Class ;
rdfs:label "regulation of cell growth involved in cardiac muscle cell development" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." ;
rdfs:subClassOf obo:GO_0001558 , obo:GO_0055021 , obo:GO_0065007 .
obo:GO_0061080 a rdfs:Class ;
rdfs:label "right horn of sinus venosus development" ;
rdfs:comment "The progression of the right horn of the sinus venosus from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_1905807 a rdfs:Class ;
rdfs:label "negative regulation of synapse pruning" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905806 , obo:GO_1905809 .
obo:CHEBI_35820 a rdfs:Class ;
rdfs:label "antiprotozoal drug" ;
rdfs:comment "Any antimicrobial drug which is used to treat or prevent protozoal infections." ;
rdfs:subClassOf obo:CHEBI_35442 , obo:CHEBI_36043 .
obo:GO_0070161 a rdfs:Class ;
rdfs:label "anchoring junction" ;
rdfs:comment "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." ;
rdfs:subClassOf obo:GO_0030054 .
obo:PATO_0002124 a rdfs:Class ;
rdfs:label "laminar" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:GO_0034769 a rdfs:Class ;
rdfs:label "basement membrane disassembly" ;
rdfs:comment "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0022617 , obo:GO_0071711 .
obo:PHIPO_0001336 a rdfs:Class ;
rdfs:label "sensitive to myclobutanil"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to myclobutanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PATO_0002007 a rdfs:Class ;
rdfs:label "convex 3-D shape" ;
rdfs:comment "A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave." ;
rdfs:subClassOf obo:PATO_0002266 .
obo:CHEBI_52549 a rdfs:Class ;
rdfs:label "sordarin" ;
rdfs:comment "An antifungal metabolite of Sordaria araneosa that inhibits protein synthesis. It has a tetracyclic diterpene glycoside structure." ;
rdfs:subClassOf obo:CHEBI_24400 , obo:CHEBI_52557 , obo:CHEBI_63367 .
obo:GO_1902275 a rdfs:Class ;
rdfs:label "regulation of chromatin organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of chromatin organization." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0071888 a rdfs:Class ;
rdfs:label "macrophage apoptotic process" ;
rdfs:comment "Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0006925 , obo:GO_0033028 , obo:GO_0071887 .
obo:GO_2000726 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051154 , obo:GO_0065007 , obo:GO_1905208 , obo:GO_2000725 .
obo:GO_1905144 a rdfs:Class ;
rdfs:label "response to acetylcholine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_1901698 , obo:GO_1901700 .
obo:GO_0046534 a rdfs:Class ;
rdfs:label "positive regulation of photoreceptor cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0045666 , obo:GO_0046532 , obo:GO_0051240 , obo:GO_0065007 .
obo:GO_0061140 a rdfs:Class ;
rdfs:label "lung secretory cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0060487 .
obo:GO_0001704 a rdfs:Class ;
rdfs:label "formation of primary germ layer" ;
rdfs:comment "The formation of the ectoderm, mesoderm and endoderm during gastrulation." ;
rdfs:subClassOf obo:GO_0048646 .
a rdfs:Class ;
rdfs:label "Cerebellum" ;
rdfs:subClassOf , obo:UBERON_0002037 .
obo:CHEBI_52209 a rdfs:Class ;
rdfs:label "aetiopathogenetic role" ;
rdfs:comment "A role played by the molecular entity or part thereof which causes the development of a pathological process." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_50780 a rdfs:Class ;
rdfs:label "appetite regulator" ;
rdfs:comment "An agent which regulates the physiologic mechanisms that control the appetite and food intake." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:PHIPO_0000333 a rdfs:Class ;
rdfs:label "pathogen cell to cell migration within host phenotype"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype which affects the directional movement of the pathogen within the host organism (GO:0044001)." ;
rdfs:subClassOf obo:PHIPO_0000332 .
obo:GO_0071696 a rdfs:Class ;
rdfs:label "ectodermal placode development" ;
rdfs:comment "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." ;
rdfs:subClassOf obo:GO_0048856 .
obo:PHIPO_0000665 a rdfs:Class ;
rdfs:label "resistance to ofloxacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0034925 a rdfs:Class ;
rdfs:label "anatomical collection" ;
rdfs:comment "A collection of anatomical structures that are alike in terms of their morphology or developmental origin." ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:GO_0010496 a rdfs:Class ;
rdfs:label "intercellular transport" ;
rdfs:comment "The movement of substances between cells." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 .
obo:GO_2000737 a rdfs:Class ;
rdfs:label "negative regulation of stem cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation." ;
rdfs:subClassOf obo:GO_0045596 , obo:GO_0065007 , obo:GO_2000736 .
obo:GO_0097454 a rdfs:Class ;
rdfs:label "Schwann cell microvillus" ;
rdfs:comment "Small finger-like extension of a Schwann cell that contacts the nodal membrane." ;
rdfs:subClassOf obo:GO_0005902 , obo:GO_0097386 .
obo:UBERON_0005020 a rdfs:Class ;
rdfs:label "mucosa of tongue" ;
rdfs:comment "A mucosa that is part of a tongue [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0003729 .
obo:CHEBI_140190 a rdfs:Class ;
rdfs:label "calcium-dependent antibiotics" ;
rdfs:comment "Any antimicrobial agent whose activity is dependent on the presence of calcium ions." ;
rdfs:subClassOf obo:CHEBI_33281 .
obo:GO_0006935 a rdfs:Class ;
rdfs:label "chemotaxis" ;
rdfs:comment "The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ;
rdfs:subClassOf obo:GO_0042330 .
obo:CL_4307026 a rdfs:Class ;
rdfs:label "Bergmann glial cell (Mmus)" ;
rdfs:comment "A Bergmann glial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr37l1 (Mmus), Ctxn3 (Mmus). It is distinguished from other Astro-Epen cells by expression of Gpr37l1, Ctxn3. These cells are located in the Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5206 Bergmann NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000644 .
obo:UBERON_0036351 a rdfs:Class ;
rdfs:label "wall of brachiocephalic artery" ;
rdfs:subClassOf obo:UBERON_0000060 , obo:UBERON_0000415 .
obo:GO_0021593 a rdfs:Class ;
rdfs:label "rhombomere morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CL_0002663 a rdfs:Class ;
rdfs:label "myocardial endocrine cell of atrium" ;
rdfs:comment "A myocardial endocrine cell that is part of the atrium." ;
rdfs:subClassOf obo:CL_0002074 .
obo:PHIPO_0001120 a rdfs:Class ;
rdfs:label "decreased protein phosphorylation"@en ;
rdfs:comment "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." ;
rdfs:subClassOf obo:PHIPO_0001119 .
obo:GO_0007399 a rdfs:Class ;
rdfs:label "nervous system development" ;
rdfs:comment "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:PHIPO_0000036 a rdfs:Class ;
rdfs:label "abnormal lipid droplet morphology" ;
rdfs:comment "A single organism phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of lipid droplets is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000478 .
obo:GO_0003044 a rdfs:Class ;
rdfs:label "regulation of systemic arterial blood pressure mediated by a chemical signal" ;
rdfs:comment "The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine." ;
rdfs:subClassOf obo:GO_0003073 .
obo:GO_0050879 a rdfs:Class ;
rdfs:label "multicellular organismal movement" ;
rdfs:comment "Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism." ;
rdfs:subClassOf obo:GO_0032501 .
obo:PHIPO_0000176 a rdfs:Class ;
rdfs:label "obsolete increased pathogen host interaction RNA binding" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is increased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." .
obo:GO_2000405 a rdfs:Class ;
rdfs:label "negative regulation of T cell migration" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000402 , obo:GO_2000404 .
obo:GO_0009449 a rdfs:Class ;
rdfs:label "GABA biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." ;
rdfs:subClassOf obo:GO_0008652 , obo:GO_0009058 , obo:GO_0170043 .
obo:CHEBI_22715 a rdfs:Class ;
rdfs:label "benzimidazoles" ;
rdfs:comment "An organic heterocyclic compound containing a benzene ring fused to an imidazole ring." ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 .
obo:GO_0002376 a rdfs:Class ;
rdfs:label "immune system process" ;
rdfs:comment "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CHEBI_149553 a rdfs:Class ;
rdfs:label "anticoronaviral agent" ;
rdfs:comment "Any antiviral agent which inhibits the activity of coronaviruses." ;
rdfs:subClassOf obo:CHEBI_22587 .
obo:CL_0008031 a rdfs:Class ;
rdfs:label "cortical interneuron"@en ;
rdfs:comment "An interneuron that has its soma located in the cerebral cortex." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_0010012 .
obo:CHEBI_33702 a rdfs:Class ;
rdfs:label "polyatomic cation" ;
rdfs:comment "A cation consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_36358 , obo:CHEBI_36916 .
obo:CHEBI_59517 a rdfs:Class ;
rdfs:label "DNA synthesis inhibitor" ;
rdfs:comment "Any substance that inhibits the synthesis of DNA." ;
rdfs:subClassOf obo:CHEBI_76932 .
obo:PR_Q61616 a rdfs:Class ;
rdfs:label "D(1A) dopamine receptor (mouse)" ;
rdfs:comment "A D(1A) dopamine receptor that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001175 , obo:PR_000029032 .
obo:CHEBI_35692 a rdfs:Class ;
rdfs:label "dicarboxylic acid" ;
rdfs:comment "Any carboxylic acid containing two carboxy groups." ;
rdfs:subClassOf obo:CHEBI_131927 , obo:CHEBI_33575 .
obo:GO_2001017 a rdfs:Class ;
rdfs:label "regulation of retrograde axon cargo transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of retrograde axon cargo transport." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0060632 , obo:GO_0065007 .
obo:PHIPO_0000009 a rdfs:Class ;
rdfs:label "gain of pathogenicity" ;
rdfs:comment "A phenotype where the ability of a pathogen, to produce an infectious disease in another organism is obtained (pathogenicity was absent and is now present)." ;
rdfs:subClassOf obo:PHIPO_0000006 .
obo:PHIPO_0000758 a rdfs:Class ;
rdfs:label "sensitive to cefpodoxime proxetil"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefpodoxime proxetil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0150098 a rdfs:Class ;
rdfs:label "glial cell-neuron signaling" ;
rdfs:comment "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum." ;
rdfs:subClassOf obo:GO_0007267 .
obo:GO_1904116 a rdfs:Class ;
rdfs:label "response to vasopressin" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus." ;
rdfs:subClassOf obo:GO_0043434 , obo:GO_0050896 .
obo:GO_0003272 a rdfs:Class ;
rdfs:label "endocardial cushion formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ;
rdfs:subClassOf obo:GO_0048646 .
obo:CHEBI_130181 a rdfs:Class ;
rdfs:label "calmodulin antagonist" ;
rdfs:comment "An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin." ;
rdfs:subClassOf obo:CHEBI_48706 .
obo:UBERON_0024045 a rdfs:Class ;
rdfs:label "white matter of the cerebellar cortex" ;
rdfs:comment "White matter that lies deep to the granular cell layer of the cerebellar cortex. It contains afferents to the cerebellar cortex and axons that run between the cerebellar cortex and the deep cerebellar nuclei." ;
rdfs:subClassOf obo:UBERON_0002316 , obo:UBERON_0019291 .
obo:GO_0014744 a rdfs:Class ;
rdfs:label "positive regulation of muscle adaptation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of muscle adaptation." ;
rdfs:subClassOf obo:GO_0043502 , obo:GO_0048584 , obo:GO_0051240 , obo:GO_0065007 .
obo:CHEBI_76790 a rdfs:Class ;
rdfs:label "EC 2.4.2.* (pentosyltransferase) inhibitor" ;
rdfs:comment "An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any pentosyltransferase (EC 2.4.2.*)." ;
rdfs:subClassOf obo:CHEBI_76662 .
obo:GO_0030858 a rdfs:Class ;
rdfs:label "positive regulation of epithelial cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." ;
rdfs:subClassOf obo:GO_0030856 , obo:GO_0045597 , obo:GO_0065007 .
obo:PHIPO_0000224 a rdfs:Class ;
rdfs:label "obsolete altered colour of host lesion with pathogen" .
obo:CHEBI_86327 a rdfs:Class ;
rdfs:label "antifungal drug" ;
rdfs:comment "Any antifungal agent used to prevent or treat fungal infections in humans or animals." ;
rdfs:subClassOf obo:CHEBI_35441 , obo:CHEBI_35718 .
obo:UBERON_0007289 a rdfs:Class ;
rdfs:label "presumptive rhombomere 1" ;
rdfs:comment "A presumptive structure that has the potential to develop into a rhombomere 1." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_0099537 a rdfs:Class ;
rdfs:label "trans-synaptic signaling" ;
rdfs:comment "Cell-cell signaling in either direction across the synaptic cleft." ;
rdfs:subClassOf obo:GO_0099536 .
obo:GO_1905073 a rdfs:Class ;
rdfs:label "regulation of tight junction disassembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of tight junction disassembly." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:UBERON_0011892 a rdfs:Class ;
rdfs:label "anterior uvea" ;
rdfs:comment "Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris." ;
rdfs:subClassOf obo:UBERON_0000481 , obo:UBERON_0010314 .
obo:GO_0061061 a rdfs:Class ;
rdfs:label "muscle structure development" ;
rdfs:comment "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_1905899 a rdfs:Class ;
rdfs:label "regulation of smooth muscle tissue development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of smooth muscle tissue development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901861 .
obo:PHIPO_0000394 a rdfs:Class ;
rdfs:label "sensitive to naftifine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to naftifine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0014057 a rdfs:Class ;
rdfs:label "positive regulation of acetylcholine secretion, neurotransmission" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine." ;
rdfs:subClassOf obo:GO_0001956 , obo:GO_0014056 , obo:GO_0032224 , obo:GO_0051954 , obo:GO_0065007 .
obo:PHIPO_0001145 a rdfs:Class ;
rdfs:label "effector-mediated suppression of host effector triggered immunity present"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion initially induced by the host activating its own hypersensitive response in defense, is subsequently suppressed by a pathogen effector." ;
rdfs:subClassOf obo:PHIPO_0000182 , obo:PHIPO_0001176 .
obo:CL_0002328 a rdfs:Class ;
rdfs:label "bronchial epithelial cell" ;
rdfs:comment "An epithelial cell of the bronchus." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002202 .
obo:PR_000014841 a rdfs:Class ;
rdfs:label "sonic hedgehog protein" ;
rdfs:comment "A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PHIPO_0001375 a rdfs:Class ;
rdfs:label "decreased number of resting structures"@en ;
rdfs:comment "A single species phenotype where the frequency of occurrence of resting structures is decreased." ;
rdfs:subClassOf obo:PHIPO_0001221 .
obo:PHIPO_0000764 a rdfs:Class ;
rdfs:label "sensitive to kanamycin A"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to kanamycin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_36820 a rdfs:Class ;
rdfs:label "ring assembly" ;
rdfs:comment "Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved." ;
rdfs:subClassOf obo:CHEBI_33595 .
obo:CHEBI_71365 a rdfs:Class ;
rdfs:label "rifampicin zwitterion" ;
rdfs:comment "A zwitterion obtained by transfer of a proton from the 5-hydroxy group to the tertiary amino group of rifampicin; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_27369 .
obo:UBERON_0001136 a rdfs:Class ;
rdfs:label "mesothelium" ;
rdfs:comment "Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri)." ;
rdfs:subClassOf obo:UBERON_0000487 , obo:UBERON_0012275 .
obo:UBERON_0011820 a rdfs:Class ;
rdfs:label "atrioventricular region" ;
rdfs:comment "An anatomical junction that divides and overlaps with and atrium and a ventricle in the heart." ;
rdfs:subClassOf obo:UBERON_0007651 .
obo:CHEBI_51454 a rdfs:Class ;
rdfs:label "cyclopropanes" ;
rdfs:comment "Cyclopropane and its derivatives formed by substitution." ;
rdfs:subClassOf obo:CHEBI_33598 .
obo:PR_000018263 a rdfs:Class ;
rdfs:label "amino acid chain" ;
rdfs:comment "An organic amino compound that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds." ;
rdfs:subClassOf obo:CHEBI_50047 , obo:COB_0000013 .
obo:CHEBI_38716 a rdfs:Class ;
rdfs:label "carboxylic acid dianion" ;
rdfs:comment "Any dianion containing at least one carboxy group." ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:PHIPO_0001317 a rdfs:Class ;
rdfs:label "sensitive to cymoxanil"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cymoxanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PR_000014419 a rdfs:Class ;
rdfs:label "protein S100-B" ;
rdfs:comment "A protein that is a translation product of the human S100B gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0007771 a rdfs:Class ;
rdfs:label "epidermis gland" ;
rdfs:comment "A gland that is part of a epidermis." ;
rdfs:subClassOf obo:UBERON_0002419 , obo:UBERON_0002530 .
obo:PHIPO_0000529 a rdfs:Class ;
rdfs:label "resistance to virginiamycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to virginiamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1902863 a rdfs:Class ;
rdfs:label "regulation of embryonic camera-type eye development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of embryonic camera-type eye development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:PHIPO_0000362 a rdfs:Class ;
rdfs:label "premature pathogen penetration into host"@en ;
rdfs:comment "A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism begins sooner than normal." ;
rdfs:subClassOf obo:PHIPO_0000331 .
obo:CHEBI_7507 a rdfs:Class ;
rdfs:label "neomycin" ;
rdfs:comment "A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections." ;
rdfs:subClassOf obo:CHEBI_22479 , obo:CHEBI_22507 .
obo:PHIPO_0000143 a rdfs:Class ;
rdfs:label "DNA binding phenotype"@en ;
rdfs:comment "A single organism phenotype that affects DNA binding. The affected gene product may be encoded by the mutated gene, or by a different gene." ;
rdfs:subClassOf obo:PHIPO_0000158 .
obo:GO_1902020 a rdfs:Class ;
rdfs:label "negative regulation of cilium-dependent cell motility" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902019 , obo:GO_2000146 .
obo:CHEBI_23004 a rdfs:Class ;
rdfs:label "carbamoyl group" ;
rdfs:comment "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." ;
rdfs:subClassOf obo:CHEBI_27207 .
obo:UBERON_0002349 a rdfs:Class ;
rdfs:label "myocardium" ;
rdfs:comment "The middle layer of the heart, comprised mainly of striated cardiac muscle fibers." ;
rdfs:subClassOf obo:UBERON_0005983 , obo:UBERON_0018260 .
obo:GO_0051904 a rdfs:Class ;
rdfs:label "pigment granule transport" ;
rdfs:comment "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0051875 , obo:GO_0051905 .
obo:CL_2000029 a rdfs:Class ;
rdfs:label "central nervous system neuron" ;
rdfs:comment "Any neuron that is part of a central nervous system." ;
rdfs:subClassOf obo:CL_0000540 .
obo:GO_0015774 a rdfs:Class ;
rdfs:label "polysaccharide transport" ;
rdfs:comment "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0008643 .
obo:CHEBI_33340 a rdfs:Class ;
rdfs:label "zinc group element atom" ;
rdfs:subClassOf obo:CHEBI_33561 .
obo:GO_0003016 a rdfs:Class ;
rdfs:label "respiratory system process" ;
rdfs:comment "A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange." ;
rdfs:subClassOf obo:GO_0003008 .
obo:CL_0000779 a rdfs:Class ;
rdfs:label "multinuclear osteoclast" ;
rdfs:comment "A specialized multinuclear osteoclast, forming a syncytium through the fusion of mononuclear precursor cells, associated with the absorption and removal of bone." ;
rdfs:subClassOf obo:CL_0000092 , obo:CL_0000783 , obo:CL_4052002 .
obo:CHEBI_76760 a rdfs:Class ;
rdfs:label "EC 3.1.* (ester hydrolase) inhibitor" ;
rdfs:comment "A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*)." ;
rdfs:subClassOf obo:CHEBI_76759 .
obo:GO_0045601 a rdfs:Class ;
rdfs:label "regulation of endothelial cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of endothelial cell differentiation." ;
rdfs:subClassOf obo:GO_0030856 , obo:GO_0065007 .
obo:CL_4023111 a rdfs:Class ;
rdfs:label "cerebral cortex pyramidal neuron" ;
rdfs:comment "A pyramidal neuron with soma located in the cerebral cortex." ;
rdfs:subClassOf obo:CL_0000598 , obo:CL_0010012 .
obo:GO_0048859 a rdfs:Class ;
rdfs:label "formation of anatomical boundary" ;
rdfs:comment "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PHIPO_0000096 a rdfs:Class ;
rdfs:label "abnormal meiosis II"@en ;
rdfs:comment "A reproductive process phenotype in which the second meiotic nuclear division is abnormal (GO:0007135)." ;
rdfs:subClassOf obo:PHIPO_0000981 .
obo:CL_4301578 a rdfs:Class ;
rdfs:label "cerebellar Golgi cell (Mmus)" ;
rdfs:comment "A cerebellar Golgi cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Zfp385c (Mmus), Tfap2b (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1148 CBX Golgi Gly-Gaba_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000119 , obo:CL_4300028 .
obo:RO_0002360 a rdf:Property ;
rdfs:label "has dendrite location"@en ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:GO_0150032 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to lysosome" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to lysosome." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0150031 , obo:GO_1903829 .
obo:PHIPO_0001105 a rdfs:Class ;
rdfs:label "gliotoxin absent from cell"@en ;
rdfs:comment "A single species cell phenotype in which the amount of gliotoxin measured in a cell is too low to detect." ;
rdfs:subClassOf obo:PHIPO_0001034 .
obo:CL_0002209 a rdfs:Class ;
rdfs:label "intermediate epitheliocyte" ;
rdfs:comment "An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells." ;
rdfs:subClassOf obo:CL_0002202 .
obo:GO_0035418 a rdfs:Class ;
rdfs:label "protein localization to synapse" ;
rdfs:comment "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_1902414 .
obo:CL_1001602 a rdfs:Class ;
rdfs:label "cerebral cortex endothelial cell" ;
rdfs:comment "A distinct endothelial cell forming the walls of the capillaries within the cerebral cortex." ;
rdfs:subClassOf obo:CL_0000115 , obo:CL_0002319 .
obo:CHEBI_64912 a rdfs:Class ;
rdfs:label "antimycobacterial drug" ;
rdfs:comment "A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy." ;
rdfs:subClassOf obo:CHEBI_36047 .
obo:GO_0097473 a rdfs:Class ;
rdfs:label "retinal rod cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0051402 , obo:GO_1990009 .
obo:GO_2000196 a rdfs:Class ;
rdfs:label "positive regulation of female gonad development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of female gonad development." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905941 , obo:GO_2000194 .
obo:CHEBI_24531 a rdfs:Class ;
rdfs:label "heterocyclic antibiotic" ;
rdfs:subClassOf obo:CHEBI_24532 .
obo:GO_0007423 a rdfs:Class ;
rdfs:label "sensory organ development" ;
rdfs:comment "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:PR_000001083 a rdfs:Class ;
rdfs:label "CD2 molecule" ;
rdfs:comment "A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_0010701 a rdfs:Class ;
rdfs:label "positive regulation of norepinephrine secretion" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine." ;
rdfs:subClassOf obo:GO_0014061 , obo:GO_0033605 , obo:GO_0065007 .
obo:GO_1901032 a rdfs:Class ;
rdfs:label "negative regulation of response to reactive oxygen species" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901031 , obo:GO_1902883 .
obo:GO_1902680 a rdfs:Class ;
rdfs:label "positive regulation of RNA biosynthetic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010557 , obo:GO_0051254 , obo:GO_0065007 , obo:GO_2001141 .
obo:PHIPO_0000057 a rdfs:Class ;
rdfs:label "normal number of sexual spores"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of sexual spores is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0000079 .
obo:PHIPO_0000406 a rdfs:Class ;
rdfs:label "nucleus absent"@en ;
rdfs:comment "A single organism phenotype in which the nucleus is absent." ;
rdfs:subClassOf obo:PHIPO_0000934 .
obo:UBERON_0000464 a rdfs:Class ;
rdfs:label "anatomical space" ;
rdfs:comment "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." ;
rdfs:subClassOf obo:UBERON_0000466 .
obo:GO_0140657 a rdfs:Class ;
rdfs:label "ATP-dependent activity" ;
rdfs:comment "A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient." ;
rdfs:subClassOf obo:GO_0003674 .
obo:GO_0044145 a rdfs:Class ;
rdfs:label "modulation of formation of structure involved in a symbiotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:GO_0006546 a rdfs:Class ;
rdfs:label "glycine catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of glycine." ;
rdfs:subClassOf obo:GO_0006544 , obo:GO_0009056 , obo:GO_0009063 , obo:GO_0170040 .
obo:GO_0010647 a rdfs:Class ;
rdfs:label "positive regulation of cell communication" ;
rdfs:comment "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0010646 , obo:GO_0048522 , obo:GO_0065007 .
obo:CHEBI_50748 a rdfs:Class ;
rdfs:label "antipsoriatic" ;
rdfs:comment "A drug used to treat psoriasis." ;
rdfs:subClassOf obo:CHEBI_50177 .
obo:PHIPO_0001131 a rdfs:Class ;
rdfs:label "increased number of host side shoots during pathogen colonization"@en ;
rdfs:comment "A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in an increased number of side shoots produced by the host organism." ;
rdfs:subClassOf obo:PHIPO_0001006 .
obo:GO_0050795 a rdfs:Class ;
rdfs:label "regulation of behavior" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0065007 .
obo:UBERON_0009569 a rdfs:Class ;
rdfs:label "subdivision of trunk" ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:UBERON_0035037 a rdfs:Class ;
rdfs:label "jaw epithelium" ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003929 .
obo:PHIPO_0000837 a rdfs:Class ;
rdfs:label "sensitive to rifabutin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to rifabutin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_65001 a rdfs:Class ;
rdfs:label "EC 3.1.1.3 (triacylglycerol lipase) inhibitor" ;
rdfs:comment "Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3)." ;
rdfs:subClassOf obo:CHEBI_76773 .
obo:GO_0060459 a rdfs:Class ;
rdfs:label "left lung development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect." ;
rdfs:subClassOf obo:GO_0030324 , obo:GO_0048856 .
obo:GO_0002286 a rdfs:Class ;
rdfs:label "T cell activation involved in immune response" ;
rdfs:comment "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0002285 , obo:GO_0042110 .
obo:UBERON_0000031 a rdfs:Class ;
rdfs:label "lamina propria of trachea" ;
rdfs:comment "A lamina propria that is part of a respiratory airway." ;
rdfs:subClassOf obo:UBERON_0000030 , obo:UBERON_0004779 .
obo:PHIPO_0000119 a rdfs:Class ;
rdfs:label "delayed timing of pathogen growth after penetration of the barrier"@en ;
rdfs:comment "A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay begins later than normal." ;
rdfs:subClassOf obo:PHIPO_0000031 .
obo:GO_0005126 a rdfs:Class ;
rdfs:label "cytokine receptor binding" ;
rdfs:comment "Binding to a cytokine receptor." ;
rdfs:subClassOf obo:GO_0005102 .
obo:GO_0033002 a rdfs:Class ;
rdfs:label "muscle cell proliferation" ;
rdfs:comment "The expansion of a muscle cell population by cell division." ;
rdfs:subClassOf obo:GO_0008283 .
obo:GO_0098982 a rdfs:Class ;
rdfs:label "GABA-ergic synapse" ;
rdfs:comment "A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory." ;
rdfs:subClassOf obo:GO_0045202 .
obo:GO_0010001 a rdfs:Class ;
rdfs:label "glial cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0008090 a rdfs:Class ;
rdfs:label "retrograde axonal transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0098930 .
obo:GO_0060089 a rdfs:Class ;
rdfs:label "molecular transducer activity" ;
rdfs:comment "A compound molecular function in which an effector function is controlled by one or more regulatory components." ;
rdfs:subClassOf obo:GO_0003674 .
obo:UBERON_0005460 a rdfs:Class ;
rdfs:label "left vitelline vein" ;
rdfs:comment "A vitelline vein that is in the left side of a multicellular organism." ;
rdfs:subClassOf obo:UBERON_0005487 , obo:UBERON_0015212 .
obo:PATO_0001873 a rdfs:Class ;
rdfs:label "cylindrical" ;
rdfs:comment "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section." ;
rdfs:subClassOf obo:PATO_0002007 .
obo:CHEBI_47985 a rdfs:Class ;
rdfs:label "enol ether" ;
rdfs:comment "Ethers ROR' where R has a double bond adjacent to the oxygen of the ether linkage." ;
rdfs:subClassOf obo:CHEBI_25698 , obo:CHEBI_78840 .
obo:CHEBI_75282 a rdfs:Class ;
rdfs:label "ergosterol biosynthesis inhibitor" ;
rdfs:comment "Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol." ;
rdfs:subClassOf obo:CHEBI_83317 .
obo:GO_0002704 a rdfs:Class ;
rdfs:label "negative regulation of leukocyte mediated immunity" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity." ;
rdfs:subClassOf obo:GO_0002698 , obo:GO_0002703 , obo:GO_0065007 .
obo:CHEBI_24837 a rdfs:Class ;
rdfs:label "inorganic peroxide" ;
rdfs:comment "Compounds of structure ROOR' in which R and R' are inorganic groups." ;
rdfs:subClassOf obo:CHEBI_24836 , obo:CHEBI_25940 .
obo:CL_4307029 a rdfs:Class ;
rdfs:label "Astro-NT NN_1 Slc36a2 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Slc36a2 (Mmus), Sfrp5 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Slc36a2, Sfrp5. These cells are located in the Midbrain, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5209 Astro-NT NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301589 .
obo:CHEBI_86482 a rdfs:Class ;
rdfs:label "strobilurin antifungal agent" ;
rdfs:comment "Any antibiotic antifungal agents whose structure is based on the antifungal agents originally isolated from the fungus Strobilurus tenacellus." ;
rdfs:subClassOf obo:CHEBI_86478 .
obo:GO_0042427 a rdfs:Class ;
rdfs:label "serotonin biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0042428 , obo:GO_0042435 , obo:GO_0046189 , obo:GO_1901162 .
obo:GO_0002522 a rdfs:Class ;
rdfs:label "leukocyte migration involved in immune response" ;
rdfs:comment "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response." ;
rdfs:subClassOf obo:GO_0002252 , obo:GO_0050900 .
obo:PR_P26952 a rdfs:Class ;
rdfs:label "interleukin-3 receptor subunit alpha (mouse)" ;
rdfs:comment "An interleukin-3 receptor class 2 alpha chain that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001865 , obo:PR_000029032 .
obo:PHIPO_0001235 a rdfs:Class ;
rdfs:label "host defense-related RNA involved in a pathogen interaction present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the host defense-related RNA usually present during infection is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001231 .
obo:GO_0140151 a rdfs:Class ;
rdfs:label "solid phase of interstitial matrix" ;
rdfs:comment "The solid compartment of the interstitial matrix, including interstitial collagens such as fibrillar and fibril-associated collagens and non-collagenous glycoproteins like fibronectin and elastin." ;
rdfs:subClassOf obo:GO_0030312 .
obo:CL_1000456 a rdfs:Class ;
rdfs:label "mesothelial cell of parietal peritoneum" ;
rdfs:comment "A mesothelial cell that is part of the parietal peritoneum." ;
rdfs:subClassOf obo:CL_0000077 , obo:CL_1000490 .
obo:PHIPO_0000078 a rdfs:Class ;
rdfs:label "abnormal asexual sporulation"@en ;
rdfs:comment "A reproductive phenotype where the process of asexual sporulation, the formation of spores derived from the products of an asexual cell division, is abnormal (GO:0030436)." ;
rdfs:subClassOf obo:PHIPO_0000047 .
obo:CHEBI_73336 a rdfs:Class ;
rdfs:label "vulnerary" ;
rdfs:comment "A drug used in treating and healing of wounds." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:UBERON_0007135 a rdfs:Class ;
rdfs:label "neural keel" ;
rdfs:comment "An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section." ;
rdfs:subClassOf obo:UBERON_0016879 .
obo:GO_2000495 a rdfs:Class ;
rdfs:label "regulation of cell proliferation involved in compound eye morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:UBERON_0011823 a rdfs:Class ;
rdfs:label "dense connective tissue" ;
rdfs:comment "Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets." ;
rdfs:subClassOf obo:UBERON_0002384 .
obo:CL_0002312 a rdfs:Class ;
rdfs:label "somatotroph" ;
rdfs:comment "An acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin." ;
rdfs:subClassOf obo:CL_0000295 , obo:CL_0000638 .
obo:CHEBI_72544 a rdfs:Class ;
rdfs:label "flavonoids" ;
rdfs:comment "Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them." ;
rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_50860 .
obo:UBERON_0009713 a rdfs:Class ;
rdfs:label "endocardium of left ventricle" ;
rdfs:comment "Any endocardium that is part of the left ventricle of the heart." ;
rdfs:subClassOf obo:UBERON_0001081 .
obo:CHEBI_404903 a rdfs:Class ;
rdfs:label "ertapenem" ;
rdfs:comment "Meropenem in which the one of the two methyl groups attached to the amide nitrogen is replaced by hydrogen while the other is replaced by a 3-carboxyphenyl group. The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract." ;
rdfs:subClassOf obo:CHEBI_46634 , obo:CHEBI_46770 .
obo:GO_0035981 a rdfs:Class ;
rdfs:label "tongue muscle cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0098528 .
obo:GO_0043043 a rdfs:Class ;
rdfs:label "peptide biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." ;
rdfs:subClassOf obo:GO_0006518 , obo:GO_0009058 .
obo:GO_2000831 a rdfs:Class ;
rdfs:label "regulation of steroid hormone secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of steroid hormone secretion." ;
rdfs:subClassOf obo:GO_0032368 , obo:GO_0044060 , obo:GO_0046883 , obo:GO_0065007 .
obo:PHIPO_0000928 a rdfs:Class ;
rdfs:label "host defense-induced reactive oxygen species absent"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host reactive oxygen species (ROS) often associated with an oxidative burst response during infection is absent or at a level too low to detect." ;
rdfs:subClassOf obo:PHIPO_0000924 .
obo:CHEBI_84264 a rdfs:Class ;
rdfs:label "EC 3.5.1.19 (nicotinamidase) inhibitor" ;
rdfs:comment "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19)." ;
rdfs:subClassOf obo:CHEBI_76807 .
obo:GO_0009755 a rdfs:Class ;
rdfs:label "hormone-mediated signaling pathway" ;
rdfs:comment "The series of molecular signals mediated by the detection of a hormone." ;
rdfs:subClassOf obo:GO_0007165 .
obo:GO_0010624 a rdfs:Class ;
rdfs:label "regulation of Schwann cell proliferation" ;
rdfs:comment "Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." ;
rdfs:subClassOf obo:GO_0060251 , obo:GO_0065007 .
a rdfs:Class ;
rdfs:label "Interbrain" ;
rdfs:subClassOf , obo:UBERON_0001894 .
obo:GO_0033605 a rdfs:Class ;
rdfs:label "positive regulation of catecholamine secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine." ;
rdfs:subClassOf obo:GO_0050433 , obo:GO_0051954 , obo:GO_0065007 , obo:GO_1903532 .
obo:PHIPO_0000968 a rdfs:Class ;
rdfs:label "absent pathogen growth after penetration of the barrier"@en ;
rdfs:comment "A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is absent." ;
rdfs:subClassOf obo:PHIPO_0000027 .
obo:UBERON_0002523 a rdfs:Class ;
rdfs:label "tunica intima" ;
rdfs:comment "The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:GO_0010937 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic microtubule depolymerization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." ;
rdfs:subClassOf obo:GO_0031114 , obo:GO_0065007 .
obo:PHIPO_0001133 a rdfs:Class ;
rdfs:label "increased cellular melanin accumulation"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of melanin in a cell is increased." ;
rdfs:subClassOf obo:PHIPO_0000287 .
obo:GO_1905879 a rdfs:Class ;
rdfs:label "regulation of oogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of oogenesis." ;
rdfs:subClassOf obo:GO_0051239 , obo:GO_0060284 , obo:GO_0065007 , obo:GO_2000241 .
obo:CHEBI_59107 a rdfs:Class ;
rdfs:label "EC 3.4.24.* (metalloendopeptidase) inhibitor" ;
rdfs:comment "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*)." ;
rdfs:subClassOf obo:CHEBI_37670 .
obo:UBERON_0010125 a rdfs:Class ;
rdfs:label "future superior salivatory nucleus" ;
rdfs:comment "A gray matter that has the potential to develop into a superior salivatory nucleus." ;
rdfs:subClassOf obo:UBERON_0002020 .
obo:GO_2000528 a rdfs:Class ;
rdfs:label "negative regulation of myeloid dendritic cell chemotaxis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000509 , obo:GO_2000527 .
obo:CHEBI_39474 a rdfs:Class ;
rdfs:label "polyazaalkane" ;
rdfs:comment "Any azaalkane in which two or more carbons in the chain are replaced by nitrogen." ;
rdfs:subClassOf obo:CHEBI_46686 , obo:CHEBI_88061 .
obo:CHEBI_33637 a rdfs:Class ;
rdfs:label "ortho-fused compound" ;
rdfs:comment "A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms." ;
rdfs:subClassOf obo:CHEBI_35293 .
obo:GO_0040017 a rdfs:Class ;
rdfs:label "positive regulation of locomotion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." ;
rdfs:subClassOf obo:GO_0040012 , obo:GO_0048518 , obo:GO_0065007 .
obo:CHEBI_76830 a rdfs:Class ;
rdfs:label "EC 5.99.1.* (miscellaneous isomerase) inhibitor" ;
rdfs:comment "An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class." ;
rdfs:subClassOf obo:CHEBI_76697 .
obo:GO_0048642 a rdfs:Class ;
rdfs:label "negative regulation of skeletal muscle tissue development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development." ;
rdfs:subClassOf obo:GO_0045843 , obo:GO_0048641 , obo:GO_0065007 .
obo:PHIPO_0000961 a rdfs:Class ;
rdfs:label "obsolete cell morphology phenotype" ;
rdfs:comment "A single species phenotype that affects the morphology of a cell." .
obo:GO_0033326 a rdfs:Class ;
rdfs:label "cerebrospinal fluid secretion" ;
rdfs:comment "The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces." ;
rdfs:subClassOf obo:GO_0007589 , obo:GO_0032941 .
obo:GO_0140272 a rdfs:Class ;
rdfs:label "exogenous protein binding" ;
rdfs:comment "Binding to a protein or protein complex from a different species, for example a pathogen molecule binding to a host protein." ;
rdfs:subClassOf obo:GO_0005515 .
obo:CHEBI_24913 a rdfs:Class ;
rdfs:label "isoprenoid" ;
rdfs:comment "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives." ;
rdfs:subClassOf obo:CHEBI_18059 .
obo:UBERON_0010259 a rdfs:Class ;
rdfs:label "1st arch mesenchyme from neural crest" ;
rdfs:comment "Mesenchyme that develops_from a neural crest and is part of a 1st arch mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0010042 , obo:UBERON_0010258 , obo:UBERON_0010359 .
obo:GO_0051246 a rdfs:Class ;
rdfs:label "regulation of protein metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." ;
rdfs:subClassOf obo:GO_0060255 , obo:GO_0065007 , obo:GO_0080090 .
obo:CHEBI_8232 a rdfs:Class ;
rdfs:label "piperacillin" ;
rdfs:comment "A penicillin in which the substituent at position 6 of the penam ring is a 2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido group." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_88187 .
obo:PHIPO_0000523 a rdfs:Class ;
rdfs:label "resistance to sordarin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to sordarin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_64766 a rdfs:Class ;
rdfs:label "cationic group" ;
rdfs:comment "A group that carries an overall positive charge." ;
rdfs:subClassOf obo:CHEBI_24433 .
obo:NCBITaxon_197563 a rdfs:Class ;
rdfs:label "Mandibulata" ;
rdfs:subClassOf obo:NCBITaxon_6656 .
obo:CHEBI_32868 a rdfs:Class ;
rdfs:label "D-prolinium" ;
rdfs:comment "An optically active form of prolinium having D-configuration." ;
rdfs:subClassOf obo:CHEBI_32872 .
a rdfs:Class ;
rdfs:label "Striatum" ;
rdfs:subClassOf , obo:UBERON_0002435 .
obo:GO_0050709 a rdfs:Class ;
rdfs:label "negative regulation of protein secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." ;
rdfs:subClassOf obo:GO_0050708 , obo:GO_0051224 , obo:GO_0065007 , obo:GO_1903531 .
obo:GO_0098972 a rdfs:Class ;
rdfs:label "anterograde dendritic transport of mitochondrion" ;
rdfs:comment "The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0098937 , obo:GO_0098939 .
obo:PHIPO_0001402 a rdfs:Class ;
rdfs:label "resistance to mandipropamid" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to mandipropamid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0055059 a rdfs:Class ;
rdfs:label "asymmetric neuroblast division" ;
rdfs:comment "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." ;
rdfs:subClassOf obo:GO_0008356 , obo:GO_0045165 , obo:GO_0055057 .
obo:UBERON_0022288 a rdfs:Class ;
rdfs:label "surface of eyeball" ;
rdfs:subClassOf obo:UBERON_0036215 .
obo:GO_0021860 a rdfs:Class ;
rdfs:label "pyramidal neuron development" ;
rdfs:comment "The progression of a pyramidal neuron from its initial formation to its mature state." ;
rdfs:subClassOf obo:GO_0021884 , obo:GO_0032502 .
obo:CL_1000412 a rdfs:Class ;
rdfs:label "endothelial cell of arteriole" ;
rdfs:comment "An endothelial cell that is part of the arteriole." ;
rdfs:subClassOf obo:CL_0000071 , obo:CL_0000115 .
obo:PHIPO_0000842 a rdfs:Class ;
rdfs:label "sensitive to piperacillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to piperacillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:GO_0062012 a rdfs:Class ;
rdfs:label "regulation of small molecule metabolic process" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:GO_1903522 a rdfs:Class ;
rdfs:label "regulation of blood circulation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of blood circulation." ;
rdfs:subClassOf obo:GO_0044057 , obo:GO_0065007 .
obo:PATO_0001300 a rdfs:Class ;
rdfs:label "optical quality" ;
rdfs:comment "An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light." ;
rdfs:subClassOf obo:PATO_0070060 .
obo:UBERON_0000377 a rdfs:Class ;
rdfs:label "maxillary nerve" ;
rdfs:comment "The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses." ;
rdfs:subClassOf obo:UBERON_0011779 .
obo:CL_0020009 a rdfs:Class ;
rdfs:label "prototypic neuron" ;
rdfs:comment "A GABAergic neuron located in the external globus pallidus (GPe) that constitutes approximately two-thirds of all GPe neurons (Mallet et al., 2012, Dodson et al., 2015). Derived from the medial ganglionic eminence, this cell selectively expresses Nkx2-1, with roughly two-thirds co-expressing parvalbumin (PV) and one-third lacking it in mice (Mallet et al., 2012; Dodson et al., 2015)." ;
rdfs:subClassOf obo:CL_0000617 , obo:CL_0012001 .
obo:GO_0003682 a rdfs:Class ;
rdfs:label "chromatin binding" ;
rdfs:comment "Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." ;
rdfs:subClassOf obo:GO_0005488 .
obo:CHEBI_22702 a rdfs:Class ;
rdfs:label "benzamides" ;
rdfs:subClassOf obo:CHEBI_22645 .
obo:PHIPO_0001123 a rdfs:Class ;
rdfs:label "viable population"@en ;
rdfs:comment "An organism population phenotype in which some organisms in the population are viable." ;
rdfs:subClassOf obo:PHIPO_0000514 .
obo:UBERON_0004883 a rdfs:Class ;
rdfs:label "lung mesenchyme" ;
rdfs:comment "The mass of tissue made up of mesenchymal cells in the lung." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0004120 .
obo:CHEBI_35276 a rdfs:Class ;
rdfs:label "ammonium compound" ;
rdfs:comment "Compounds (NH4+)Y− and derivatives, in which one or more of the hydrogens bonded to nitrogen have been replaced with univalent groups." ;
rdfs:subClassOf obo:CHEBI_51143 .
obo:CL_0000007 a rdfs:Class ;
rdfs:label "early embryonic cell (metazoa)" ;
rdfs:comment "A cell found in the embryo before the formation of all the germ layers is complete." ;
rdfs:subClassOf obo:CL_0002321 .
obo:PATO_0002052 a rdfs:Class ;
rdfs:label "decreased occurrence" ;
rdfs:comment "An occurrence which is relatively low." ;
rdfs:subClassOf obo:PATO_0000057 , obo:PATO_0002302 .
obo:CL_0008009 a rdfs:Class ;
rdfs:label "transversely striated visceral muscle cell"@en ;
rdfs:comment "A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods." ;
rdfs:subClassOf obo:CL_0008007 , obo:CL_0008008 .
obo:GO_0050678 a rdfs:Class ;
rdfs:label "regulation of epithelial cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of epithelial cell proliferation." ;
rdfs:subClassOf obo:GO_0042127 , obo:GO_0065007 .
obo:PHIPO_0000067 a rdfs:Class ;
rdfs:label "asexual spores decreased in size"@en ;
rdfs:comment "A reproductive morphology phenotype where the size of the asexual spore is decreased." ;
rdfs:subClassOf obo:PHIPO_0000081 .
obo:CHEBI_52132 a rdfs:Class ;
rdfs:label "oxacillin(1-)" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:CHEBI_26776 a rdfs:Class ;
rdfs:label "stilbenoid" ;
rdfs:comment "Any olefinic compound characterised by a 1,2-diphenylethylene backbone." ;
rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_78840 .
obo:GO_0060047 a rdfs:Class ;
rdfs:label "heart contraction" ;
rdfs:comment "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body." ;
rdfs:subClassOf obo:GO_0003015 .
obo:CHEBI_73913 a rdfs:Class ;
rdfs:label "antifolate" ;
rdfs:comment "An antimetabolite that impairs the action of folic acids" ;
rdfs:subClassOf obo:CHEBI_35221 .
obo:GO_1900180 a rdfs:Class ;
rdfs:label "regulation of protein localization to nucleus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of protein localization to nucleus." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0065007 .
obo:GO_0051782 a rdfs:Class ;
rdfs:label "negative regulation of cell division" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0051302 , obo:GO_0065007 .
obo:PHIPO_0001183 a rdfs:Class ;
rdfs:label "obsolete host resistance to pathogen phenotype" ;
rdfs:comment "A phenotype that is relevant to host resistance to a given pathogen." .
obo:UBERON_0002240 a rdfs:Class ;
rdfs:label "spinal cord" ;
rdfs:comment "Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO)." ;
rdfs:subClassOf obo:UBERON_0000489 , obo:UBERON_0004121 , obo:UBERON_0005174 , obo:UBERON_0010314 .
obo:PHIPO_0001142 a rdfs:Class ;
rdfs:label "normal pathogen protein localization to host chloroplast"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the localization of a pathogen protein to the host chloroplast is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001175 .
obo:UBERON_0001869 a rdfs:Class ;
rdfs:label "cerebral hemisphere" ;
rdfs:comment "One of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter.[FMA]." ;
rdfs:subClassOf obo:UBERON_0000064 , obo:UBERON_0015212 .
obo:UBERON_0012193 a rdfs:Class ;
rdfs:label "phrenic vein" ;
rdfs:comment "The veins that run parallel to the phrenic arteries which include the two superior and two inferior phrenic veins." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:GO_1902017 a rdfs:Class ;
rdfs:label "regulation of cilium assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cilium assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0120032 , obo:GO_1902115 .
obo:GO_0021895 a rdfs:Class ;
rdfs:label "cerebral cortex neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex." ;
rdfs:subClassOf obo:GO_0021879 , obo:GO_0030154 .
obo:CHEBI_22160 a rdfs:Class ;
rdfs:label "acetamides" ;
rdfs:comment "Compounds with the general formula RNHC(=O)CH3." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:CHEBI_45081 a rdfs:Class ;
rdfs:label "pentamidine" ;
rdfs:comment "A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease." ;
rdfs:subClassOf obo:CHEBI_35359 , obo:CHEBI_35618 , obo:CHEBI_46786 .
obo:CL_4033018 a rdfs:Class ;
rdfs:label "lung megakaryocyte" ;
rdfs:comment "A megakaryocyte that is resident in the lung connective tissue." ;
rdfs:subClassOf obo:CL_0000556 , obo:CL_0002320 .
obo:GO_0051235 a rdfs:Class ;
rdfs:label "maintenance of location" ;
rdfs:comment "Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0051179 .
a rdfs:Class ;
rdfs:label "Hindbrain" ;
rdfs:subClassOf , obo:UBERON_0002028 .
obo:PHIPO_0000782 a rdfs:Class ;
rdfs:label "sensitive to nifurtimox"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to nifurtimox. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0000391 a rdfs:Class ;
rdfs:label "leptomeninx" ;
rdfs:comment "Pia mater or arachnoid mater." ;
rdfs:subClassOf obo:UBERON_0002360 .
obo:PATO_0002051 a rdfs:Class ;
rdfs:label "increased occurrence" ;
rdfs:comment "An occurrence which is relatively high." ;
rdfs:subClassOf obo:PATO_0000057 , obo:PATO_0002304 .
obo:CHEBI_71645 a rdfs:Class ;
rdfs:label "type A lantibiotic" ;
rdfs:comment "Any lantibiotic which has which has a long, flexible structure." ;
rdfs:subClassOf obo:CHEBI_71644 .
obo:PHIPO_0000864 a rdfs:Class ;
rdfs:label "sensitive to netilmicin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to netilmicin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0032970 a rdfs:Class ;
rdfs:label "regulation of actin filament-based process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0071675 a rdfs:Class ;
rdfs:label "regulation of mononuclear cell migration" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." ;
rdfs:subClassOf obo:GO_0002685 , obo:GO_0065007 .
obo:CL_0000638 a rdfs:Class ;
rdfs:label "acidophil cell of pars distalis of adenohypophysis" ;
rdfs:comment "An acidophilic chromophil cell that of the anterior pituitary gland." ;
rdfs:subClassOf obo:CL_0000637 .
obo:GO_0009059 a rdfs:Class ;
rdfs:label "macromolecule biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0043170 .
obo:PHIPO_0001361 a rdfs:Class ;
rdfs:label "normal growth on kresoxim-methyl" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to kresoxim-methyl (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:PATO_0045073 a rdfs:Class ;
rdfs:label "normal process quality" ;
rdfs:comment "A quality of a process that has a value that is normal or average." ;
rdfs:subClassOf obo:PATO_0001236 .
obo:PR_Q61549 a rdfs:Class ;
rdfs:label "adhesion G protein-coupled receptor E1 (mouse)" ;
rdfs:comment "An adhesion G protein-coupled receptor E1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001813 , obo:PR_000029032 .
obo:CHEBI_59769 a rdfs:Class ;
rdfs:label "acetal" ;
rdfs:comment "An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' ≠ H). Mixed acetals have R'' and R''' groups which differ." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:GO_2001198 a rdfs:Class ;
rdfs:label "regulation of dendritic cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dendritic cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902105 .
obo:UBERON_0000005 a rdfs:Class ;
rdfs:label "chemosensory organ" ;
rdfs:subClassOf obo:UBERON_0000020 .
obo:GO_0015031 a rdfs:Class ;
rdfs:label "protein transport" ;
rdfs:comment "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0045184 , obo:GO_0071705 .
obo:GO_0051961 a rdfs:Class ;
rdfs:label "negative regulation of nervous system development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0051960 , obo:GO_0065007 .
obo:GO_1901860 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial DNA metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process." ;
rdfs:subClassOf obo:GO_0010638 , obo:GO_0010821 , obo:GO_0051054 , obo:GO_0065007 , obo:GO_1901858 .
obo:GO_1903537 a rdfs:Class ;
rdfs:label "meiotic cell cycle process involved in oocyte maturation" ;
rdfs:comment "Any meiotic cell cycle process that is involved in oocyte maturation." ;
rdfs:subClassOf obo:GO_1903046 .
obo:CHEBI_39418 a rdfs:Class ;
rdfs:label "straight-chain saturated fatty acid" ;
rdfs:comment "Any saturated fatty acid lacking a side-chain." ;
rdfs:subClassOf obo:CHEBI_26607 , obo:CHEBI_59202 .
obo:GO_0080171 a rdfs:Class ;
rdfs:label "lytic vacuole organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole." ;
rdfs:subClassOf obo:GO_0007033 , obo:GO_0016043 .
obo:CL_0000114 a rdfs:Class ;
rdfs:label "surface ectodermal cell" ;
rdfs:comment "An ectodermal cell that is part of the external ectoderm, forming the outermost layer of the developing embryo. It is characterized by its polarized nature, with distinct apical and basal surfaces (Ferrante Jr., Reinke, & Stanley, 1995). Surface ectodermal cell gives rise to the epidermis, hair follicles, nails, sensory organs, and specialized structures like the apical ectodermal ridge crucial for limb development (Skoufa et al., 2024)." ;
rdfs:subClassOf obo:CL_0000221 .
obo:GO_1905084 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial translational elongation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation." ;
rdfs:subClassOf obo:GO_0045901 , obo:GO_0065007 , obo:GO_1905082 .
obo:CHEBI_52211 a rdfs:Class ;
rdfs:label "physiological role" ;
rdfs:comment "A biological role relating to the normal mechanisms and their interactions within a living system." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:GO_1904738 a rdfs:Class ;
rdfs:label "vascular associated smooth muscle cell migration" ;
rdfs:comment "The orderly movement of a vascular associated smooth muscle cell from one site to another." ;
rdfs:subClassOf obo:GO_0014909 , obo:GO_0016477 .
obo:UBERON_0010313 a rdfs:Class ;
rdfs:label "neural crest-derived structure" ;
rdfs:comment "An anatomical structure that develops from the neural crest." ;
rdfs:subClassOf obo:UBERON_0000061 , obo:UBERON_0004121 , obo:UBERON_0010314 .
obo:UBERON_0004253 a rdfs:Class ;
rdfs:label "skin muscle" ;
rdfs:comment "Any muscle organ that is part of a skin of body [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001630 .
obo:GO_0140245 a rdfs:Class ;
rdfs:label "regulation of translation at postsynapse" ;
rdfs:comment "Any process that regulates translation occurring at the postsynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0140243 .
obo:PHIPO_0001052 a rdfs:Class ;
rdfs:label "hyper-smooth unicellular colony shape"@en ;
rdfs:comment "A single species colony shape phenotype where the colony is smoother than normal." ;
rdfs:subClassOf obo:PHIPO_0001051 .
obo:GO_0043085 a rdfs:Class ;
rdfs:label "positive regulation of catalytic activity" ;
rdfs:comment "Any process that activates or increases the activity of an enzyme." ;
rdfs:subClassOf obo:GO_0044093 , obo:GO_0050790 , obo:GO_0065007 .
obo:GO_0044565 a rdfs:Class ;
rdfs:label "dendritic cell proliferation" ;
rdfs:comment "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0032943 .
obo:CHEBI_52498 a rdfs:Class ;
rdfs:label "zineb" ;
rdfs:comment "A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU." ;
rdfs:subClassOf obo:CHEBI_33839 , obo:CHEBI_36566 , obo:CHEBI_83060 .
obo:CHEBI_35366 a rdfs:Class ;
rdfs:label "fatty acid" ;
rdfs:comment "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids." ;
rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_25384 .
obo:CHEBI_747204 a rdfs:Class ;
rdfs:label "reference compound" ;
rdfs:comment "Any well-characterized compound that serves as a standard for the identification, quantification, calibration, or quality control of substances in scientific analysis." ;
rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_51086 .
obo:UBERON_0003565 a rdfs:Class ;
rdfs:label "hindbrain dura mater" ;
rdfs:comment "A dura mater that is part of a hindbrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002092 , obo:UBERON_0002363 , obo:UBERON_0003291 .
obo:GO_0007409 a rdfs:Class ;
rdfs:label "axonogenesis" ;
rdfs:comment "De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048812 .
obo:GO_0022618 a rdfs:Class ;
rdfs:label "protein-RNA complex assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0065003 , obo:GO_0071826 .
obo:GO_1990849 a rdfs:Class ;
rdfs:label "vacuolar localization" ;
rdfs:comment "Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell." ;
rdfs:subClassOf obo:GO_0051179 , obo:GO_0051640 .
obo:CHEBI_28864 a rdfs:Class ;
rdfs:label "tobramycin" ;
rdfs:comment "A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring." ;
rdfs:subClassOf obo:CHEBI_22479 , obo:CHEBI_61689 .
obo:GO_0014075 a rdfs:Class ;
rdfs:label "response to amine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." ;
rdfs:subClassOf obo:GO_0050896 , obo:GO_1901698 .
obo:UBERON_0005362 a rdfs:Class ;
rdfs:label "vagus X ganglion" ;
rdfs:comment "The group of sensory neuron cell bodies associated with the vagus nerve." ;
rdfs:subClassOf obo:UBERON_0000045 , obo:UBERON_0009127 .
obo:GO_1905485 a rdfs:Class ;
rdfs:label "positive regulation of motor neuron migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of motor neuron migration." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905483 , obo:GO_2001224 .
obo:COB_0000013 a rdfs:Class .
obo:UBERON_0010337 a rdfs:Class ;
rdfs:label "mandibular process mesenchyme from head mesenchyme" ;
rdfs:comment "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0006904 , obo:UBERON_0006905 .
obo:UBERON_0003128 a rdfs:Class ;
rdfs:label "cranium" ;
rdfs:comment "Upper portion of the skull that excludes the mandible (when present in the organism)." ;
rdfs:subClassOf obo:UBERON_0000075 .
obo:CHEBI_71181 a rdfs:Class ;
rdfs:label "Sir2 inhibitor" ;
rdfs:comment "An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2." ;
rdfs:subClassOf obo:CHEBI_61115 .
obo:GO_0031347 a rdfs:Class ;
rdfs:label "regulation of defense response" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a defense response." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080134 .
obo:GO_0031453 a rdfs:Class ;
rdfs:label "positive regulation of heterochromatin formation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of heterochromatin formation." ;
rdfs:subClassOf obo:GO_0031445 , obo:GO_0044089 , obo:GO_0065007 , obo:GO_0120263 .
obo:UBERON_0011216 a rdfs:Class ;
rdfs:label "organ system subdivision" ;
rdfs:comment "A subdivision of an anatomical system." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:GO_2000026 a rdfs:Class ;
rdfs:label "regulation of multicellular organismal development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of multicellular organismal development." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0051239 , obo:GO_0065007 .
obo:PHIPO_0000582 a rdfs:Class ;
rdfs:label "resistance to cefuroxime"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cefuroxime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0002020 a rdfs:Class ;
rdfs:label "gray matter" ;
rdfs:comment "A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons." ;
rdfs:subClassOf obo:UBERON_0011215 .
obo:GO_0045605 a rdfs:Class ;
rdfs:label "negative regulation of epidermal cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation." ;
rdfs:subClassOf obo:GO_0030857 , obo:GO_0045604 , obo:GO_0045683 , obo:GO_0065007 .
obo:GO_0021682 a rdfs:Class ;
rdfs:label "nerve maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:CHEBI_26130 a rdfs:Class ;
rdfs:label "biological pigment" ;
rdfs:comment "An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light." ;
rdfs:subClassOf obo:CHEBI_52208 .
obo:UBERON_0014538 a rdfs:Class ;
rdfs:label "subdivision of spinal cord central canal" ;
rdfs:comment "A subdivision of the central canal of the spinal cord along its anterior-posterior axis. This is typically subdivided into cervical, thoracic, lumbar and sacral segments." ;
rdfs:subClassOf obo:UBERON_0004111 .
obo:UBERON_0012418 a rdfs:Class ;
rdfs:label "respiratory system venous smooth muscle" ;
rdfs:comment "A smooth muscle tissue that is part of a respiratory system venous blood vessel." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004696 .
obo:UBERON_0036073 a rdfs:Class ;
rdfs:label "respiratory primordium mesenchyme" ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:PHIPO_0000654 a rdfs:Class ;
rdfs:label "resistance to valinomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to valinomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0061552 a rdfs:Class ;
rdfs:label "ganglion morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of ganglion are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048729 .
obo:GO_0051459 a rdfs:Class ;
rdfs:label "regulation of corticotropin secretion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell." ;
rdfs:subClassOf obo:GO_0044060 , obo:GO_0065007 , obo:GO_0090276 .
obo:GO_0070831 a rdfs:Class ;
rdfs:label "basement membrane assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0071711 , obo:GO_0085029 .
obo:CL_0002595 a rdfs:Class ;
rdfs:label "smooth muscle cell of the subclavian artery" ;
rdfs:comment "A smooth muscle cell of the subclavian artery." ;
rdfs:subClassOf obo:CL_0000359 , obo:CL_0019018 .
obo:CL_4301580 a rdfs:Class ;
rdfs:label "CBX MLI Megf11 Gaba_2 molecular layer interneuron (Mmus)" ;
rdfs:comment "A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Pvalb (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1150 CBX MLI Megf11 Gaba_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300351 .
obo:GO_0048729 a rdfs:Class ;
rdfs:label "tissue morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a tissue are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0014859 a rdfs:Class ;
rdfs:label "negative regulation of skeletal muscle cell proliferation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0014857 , obo:GO_0065007 .
obo:CHEBI_39317 a rdfs:Class ;
rdfs:label "growth regulator" ;
rdfs:comment "Any chemical substance that inhibits the life-cycle of an organism." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_33697 a rdfs:Class ;
rdfs:label "ribonucleic acid" ;
rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." ;
rdfs:subClassOf obo:CHEBI_33696 .
obo:UBERON_0002197 a rdfs:Class ;
rdfs:label "median eminence of neurohypophysis" ;
rdfs:comment "Elevation on the ventral surface of the brain located at the zone of attachment between the hypothalamic floor and the hypophysis (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed., 2005, pg. 446)." ;
rdfs:subClassOf obo:UBERON_0003296 , obo:UBERON_0003937 , obo:UBERON_0010134 .
obo:UBERON_0000964 a rdfs:Class ;
rdfs:label "cornea" ;
rdfs:comment "The transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure." ;
rdfs:subClassOf obo:UBERON_0010000 , obo:UBERON_0010313 .
obo:CHEBI_18254 a rdfs:Class ;
rdfs:label "ribonucleoside" ;
rdfs:comment "Any nucleoside where the sugar component is D-ribose." ;
rdfs:subClassOf obo:CHEBI_33838 , obo:CHEBI_47019 .
obo:GO_2000248 a rdfs:Class ;
rdfs:label "negative regulation of establishment or maintenance of neuroblast polarity" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity." ;
rdfs:subClassOf obo:GO_0010454 , obo:GO_0032878 , obo:GO_0045769 , obo:GO_0065007 .
obo:UBERON_0005317 a rdfs:Class ;
rdfs:label "pulmonary artery endothelium" ;
rdfs:comment "An pulmonary artery endothelium is an epithelium that lines the pulmonary artery[GO]." ;
rdfs:subClassOf obo:UBERON_0001917 , obo:UBERON_0001986 .
obo:PHIPO_0000029 a rdfs:Class ;
rdfs:label "obsolete abnormal mating phenotype prior to penetration" ;
rdfs:comment "Is this a bit too specific? should this be with reproduction?" .
obo:GO_0002066 a rdfs:Class ;
rdfs:label "columnar/cuboidal epithelial cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ;
rdfs:subClassOf obo:GO_0002064 , obo:GO_0032502 .
obo:CL_1000362 a rdfs:Class ;
rdfs:label "transitional myocyte of interventricular septum" ;
rdfs:comment "A transitional myocyte that is part of the interventricular septum." ;
rdfs:subClassOf obo:CL_0002073 , obo:CL_2000022 .
obo:GO_0010938 a rdfs:Class ;
rdfs:label "cytoplasmic microtubule depolymerization" ;
rdfs:comment "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." ;
rdfs:subClassOf obo:GO_0007019 , obo:GO_0031122 .
obo:GO_0010717 a rdfs:Class ;
rdfs:label "regulation of epithelial to mesenchymal transition" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:GO_0022607 a rdfs:Class ;
rdfs:label "cellular component assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a cellular component." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0016043 .
obo:GO_0140820 a rdfs:Class ;
rdfs:label "cytosol to Golgi apparatus transport" ;
rdfs:comment "The directed movement of substances from the cytosol into the Golgi apparatus of a cell." ;
rdfs:subClassOf obo:GO_0010496 , obo:GO_0055085 .
obo:PHIPO_0000294 a rdfs:Class ;
rdfs:label "obsolete normal organism morphology phenotype" .
obo:PHIPO_0000641 a rdfs:Class ;
rdfs:label "resistance to cefaclor"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cefaclor. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_60979 a rdfs:Class ;
rdfs:label "alpha-glucoside" ;
rdfs:comment "A glucoside in which the anomeric carbon of the glycosidic bond is in an α configuration" ;
rdfs:subClassOf obo:CHEBI_24278 .
obo:UBERON_0014610 a rdfs:Class ;
rdfs:label "thoracic spinal cord ventral horn" ;
rdfs:comment "A ventral horn of spinal cord that is part of a thoracic spinal cord." ;
rdfs:subClassOf obo:UBERON_0002257 .
obo:GO_1902986 a rdfs:Class ;
rdfs:label "regulation of lysine biosynthetic process via aminoadipic acid" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid." ;
rdfs:subClassOf obo:GO_0062012 , obo:GO_0065007 , obo:GO_2000282 .
obo:GO_1901609 a rdfs:Class ;
rdfs:label "negative regulation of vesicle transport along microtubule" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0065007 , obo:GO_1901608 .
obo:CL_4301579 a rdfs:Class ;
rdfs:label "CBX MLI Megf11 Gaba_1 molecular layer interneuron (Mmus)" ;
rdfs:comment "A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dnah11 (Mmus), Sla (Mmus), Gldc (Mmus), Sdk2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1149 CBX MLI Megf11 Gaba_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300351 .
obo:GO_1901628 a rdfs:Class ;
rdfs:label "positive regulation of postsynaptic membrane organization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization." ;
rdfs:subClassOf obo:GO_0051130 , obo:GO_0065007 , obo:GO_1901626 .
obo:GO_0050896 a rdfs:Class ;
rdfs:label "response to stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." ;
rdfs:subClassOf obo:GO_0008150 .
obo:GO_0031045 a rdfs:Class ;
rdfs:label "dense core granule" ;
rdfs:comment "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted." ;
rdfs:subClassOf obo:GO_0030141 .
obo:UBERON_0003218 a rdfs:Class ;
rdfs:label "ovary septum" ;
rdfs:comment "Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]." ;
rdfs:subClassOf obo:UBERON_0003037 .
obo:GO_1902679 a rdfs:Class ;
rdfs:label "negative regulation of RNA biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010558 , obo:GO_0051253 , obo:GO_0065007 , obo:GO_2001141 .
obo:GO_0072089 a rdfs:Class ;
rdfs:label "stem cell proliferation" ;
rdfs:comment "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ;
rdfs:subClassOf obo:GO_0008283 .
obo:CHEBI_3892 a rdfs:Class .
obo:GO_0140029 a rdfs:Class ;
rdfs:label "exocytic process" ;
rdfs:comment "The cellular processes that contribute to exocytosis." ;
rdfs:subClassOf obo:GO_0009987 .
obo:PHIPO_0000112 a rdfs:Class ;
rdfs:label "obsolete non-functional penetration structure present" .
obo:GO_0043005 a rdfs:Class ;
rdfs:label "neuron projection" ;
rdfs:comment "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." ;
rdfs:subClassOf obo:GO_0120025 .
obo:GO_0070446 a rdfs:Class ;
rdfs:label "negative regulation of oligodendrocyte progenitor proliferation" ;
rdfs:comment "Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation." ;
rdfs:subClassOf obo:GO_0014014 , obo:GO_0065007 , obo:GO_0070445 , obo:GO_2000178 .
obo:PHIPO_0001064 a rdfs:Class ;
rdfs:label "normal RNA level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of RNA measured in a cell is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." ;
rdfs:subClassOf obo:PHIPO_0001038 .
obo:CL_0001027 a rdfs:Class ;
rdfs:label "CD7-negative lymphoid progenitor cell" ;
rdfs:comment "CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative." ;
rdfs:subClassOf obo:CL_0000051 , obo:CL_0001012 .
obo:UBERON_0009145 a rdfs:Class ;
rdfs:label "pharyngeal region of foregut" ;
rdfs:subClassOf obo:UBERON_0005423 .
obo:GO_0170033 a rdfs:Class ;
rdfs:label "L-amino acid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving an L-amino acid." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_1901605 .
obo:PHIPO_0000248 a rdfs:Class ;
rdfs:label "abolished protein localization to nucleus"@en ;
rdfs:comment "A single organism phenotype in which the localization of a protein to the nucleus is abolished (GO:0034504)." ;
rdfs:subClassOf obo:PHIPO_0000245 .
obo:CHEBI_36622 a rdfs:Class ;
rdfs:label "benzimidazole" ;
rdfs:comment "A mancude organic heterobicyclic parent that is a heterocyclic organic compound comprising fused benzene and imidazole rings." ;
rdfs:subClassOf obo:CHEBI_22715 , obo:CHEBI_35570 .
obo:GO_0002725 a rdfs:Class ;
rdfs:label "negative regulation of T cell cytokine production" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production." ;
rdfs:subClassOf obo:GO_0002710 , obo:GO_0002719 , obo:GO_0002724 , obo:GO_0065007 .
obo:CHEBI_27026 a rdfs:Class ;
rdfs:label "toxin" ;
rdfs:comment "Poisonous substance produced by a biological organism such as a microbe, animal or plant." ;
rdfs:subClassOf obo:CHEBI_25212 , obo:CHEBI_64909 .
obo:UBERON_0005157 a rdfs:Class ;
rdfs:label "epithelial fold" ;
rdfs:comment "An epithelial sheet bent on a linear axis." ;
rdfs:subClassOf obo:UBERON_0000483 .
obo:GO_0098749 a rdfs:Class ;
rdfs:label "cerebellar neuron development" ;
rdfs:comment "The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0021954 , obo:GO_0032502 .
obo:GO_0098908 a rdfs:Class ;
rdfs:label "regulation of neuronal action potential" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0051969 , obo:GO_0098900 .
obo:CHEBI_76663 a rdfs:Class ;
rdfs:label "EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor" ;
rdfs:comment "A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*)." ;
rdfs:subClassOf obo:CHEBI_76834 .
obo:UBERON_0001087 a rdfs:Class ;
rdfs:label "pleural fluid" ;
rdfs:comment "Transudate contained in the pleural cavity." ;
rdfs:subClassOf obo:UBERON_0007779 , obo:UBERON_0036244 .
obo:GO_2000795 a rdfs:Class ;
rdfs:label "negative regulation of epithelial cell proliferation involved in lung morphogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." ;
rdfs:subClassOf obo:GO_0050680 , obo:GO_0065007 , obo:GO_2000794 .
obo:UBERON_0002422 a rdfs:Class ;
rdfs:label "fourth ventricle" ;
rdfs:comment "Part of the ventricular system of the brain, forming a single large irregularly shaped cavity located on the midline of the rhombencephalon, between the medulla, pons and the isthmus ventrally and the cerebellum dorsally. It is continuous with the cerebral aqueduct anteriorally and the central canal of the spinal cord posteriorly. It communicates with the subarachnoid space through its lateral and median apertures." ;
rdfs:subClassOf obo:UBERON_0004086 .
obo:GO_1990049 a rdfs:Class ;
rdfs:label "retrograde neuronal dense core vesicle transport" ;
rdfs:comment "The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0008090 , obo:GO_0047496 , obo:GO_0099519 .
obo:CHEBI_18946 a rdfs:Class ;
rdfs:label "delta-lactone" ;
rdfs:comment "A lactone having a six-membered lactone ring." ;
rdfs:subClassOf obo:CHEBI_25000 .
obo:GO_0006906 a rdfs:Class ;
rdfs:label "vesicle fusion" ;
rdfs:comment "Fusion of the membrane of a transport vesicle with its target membrane." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0016050 , obo:GO_0090174 .
obo:GO_0048066 a rdfs:Class ;
rdfs:label "developmental pigmentation" ;
rdfs:comment "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." ;
rdfs:subClassOf obo:GO_0043473 .
obo:CHEBI_49319 a rdfs:Class ;
rdfs:label "carbocyclic antibiotic" ;
rdfs:subClassOf obo:CHEBI_33598 .
obo:UBERON_0003099 a rdfs:Class ;
rdfs:label "cranial neural crest" ;
rdfs:comment "Neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage." ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:UBERON_0003269 a rdfs:Class ;
rdfs:label "skeletal muscle tissue of eye" ;
rdfs:comment "A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001134 .
obo:PHIPO_0001092 a rdfs:Class ;
rdfs:label "increased chitin level in asexual spore"@en ;
rdfs:comment "A single species cell phenotype in which the amount of chitin measured in the spore is higher than normal" ;
rdfs:subClassOf obo:PHIPO_0001036 , obo:PHIPO_0001094 .
obo:GO_0014041 a rdfs:Class ;
rdfs:label "regulation of neuron maturation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." ;
rdfs:subClassOf obo:GO_0045664 , obo:GO_0065007 , obo:GO_1903429 .
obo:PHIPO_0000231 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction toxin biosynthetic process phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." .
obo:GO_1905563 a rdfs:Class ;
rdfs:label "negative regulation of vascular endothelial cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation." ;
rdfs:subClassOf obo:GO_0001937 , obo:GO_0065007 , obo:GO_1905562 .
obo:UBERON_0014371 a rdfs:Class ;
rdfs:label "future telencephalon" ;
rdfs:comment "Embryonic structure that gives rise to the telencephalon." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:CL_0000035 a rdfs:Class ;
rdfs:label "single fate stem cell" ;
rdfs:comment "A stem cell that self-renews as well as give rise to a single mature cell type." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000723 .
obo:UBERON_0008946 a rdfs:Class ;
rdfs:label "lung parenchyma" ;
rdfs:comment "A parenchyma that is part of a lung." ;
rdfs:subClassOf obo:UBERON_0000353 .
obo:GO_0042268 a rdfs:Class ;
rdfs:label "regulation of cytolysis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:GO_0048814 a rdfs:Class ;
rdfs:label "regulation of dendrite morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dendrite morphogenesis." ;
rdfs:subClassOf obo:GO_0022603 , obo:GO_0050773 , obo:GO_0065007 .
obo:CHEBI_87200 a rdfs:Class ;
rdfs:label "dicarboximide antifungal agent" ;
rdfs:comment "A compound that has significant antifungal properties whose structure contains a dicarboximide moiety." ;
rdfs:subClassOf obo:CHEBI_35356 .
obo:UBERON_0002558 a rdfs:Class ;
rdfs:label "organ cavity" ;
rdfs:subClassOf obo:UBERON_0002553 .
obo:GO_0060322 a rdfs:Class ;
rdfs:label "head development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0004120 a rdfs:Class ;
rdfs:label "mesoderm-derived structure" ;
rdfs:comment "An anatomical structure that develops (entirely or partially) from the mesoderm." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:CHEBI_747325 a rdfs:Class ;
rdfs:label "additive" ;
rdfs:comment "a role for a chemical additive to a mixture" ;
rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_51086 .
obo:PHIPO_0000741 a rdfs:Class ;
rdfs:label "sensitive to difenoconazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to difenoconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0006833 a rdfs:Class ;
rdfs:label "lumen of trachea" ;
rdfs:comment "An anatomical space that surrounded_by a trachea." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:PHIPO_0000417 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction pathogen carbohydrate binding phenotype" .
obo:CHEBI_67079 a rdfs:Class ;
rdfs:label "anti-inflammatory agent" ;
rdfs:comment "Any compound that has anti-inflammatory effects." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_0070134 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial translational initiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." ;
rdfs:subClassOf obo:GO_0045948 , obo:GO_0065007 , obo:GO_0070131 , obo:GO_0070132 .
obo:CL_0010008 a rdfs:Class ;
rdfs:label "cardiac endothelial cell" ;
rdfs:comment "Any endothelial cell that is part of some heart." ;
rdfs:subClassOf obo:CL_0000115 , obo:CL_0002494 .
obo:UBERON_0002476 a rdfs:Class ;
rdfs:label "lateral globus pallidus" ;
rdfs:comment "The more lateral of the two segments of the globus pallidus, abutting the putamen." ;
rdfs:subClassOf obo:UBERON_0005401 .
obo:PHIPO_0001224 a rdfs:Class ;
rdfs:label "increased chitin hydrolysis present"@en ;
rdfs:comment "A single species metabolic cellular process phenotype, in which the occurrence of a pathogen effector preventing the hydrolysis of chitin by chitinases is decreased (chitin hydrolysis is increased)." ;
rdfs:subClassOf obo:PHIPO_0001225 .
obo:UBERON_8600004 a rdfs:Class ;
rdfs:label "visceral muscle tissue" ;
rdfs:comment "A muscle tissue that is associated with soft internal organs (viscera)." ;
rdfs:subClassOf obo:UBERON_0002385 .
obo:CHEBI_29700 a rdfs:Class ;
rdfs:label "tylactone" ;
rdfs:comment "A 16-membererd macrolide that is the aglycone of the antibiotic 5-O-β-D-mycaminosyltylactone." ;
rdfs:subClassOf obo:CHEBI_23824 , obo:CHEBI_25106 , obo:CHEBI_51689 .
obo:GO_0090026 a rdfs:Class ;
rdfs:label "positive regulation of monocyte chemotaxis" ;
rdfs:comment "Any process that increases the frequency, rate, or extent of monocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0002690 , obo:GO_0065007 , obo:GO_0071677 , obo:GO_0090025 .
obo:GO_0010818 a rdfs:Class ;
rdfs:label "T cell chemotaxis" ;
rdfs:comment "The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0048247 , obo:GO_0072678 .
obo:GO_0051716 a rdfs:Class ;
rdfs:label "cellular response to stimulus" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0050896 .
obo:CL_4301585 a rdfs:Class ;
rdfs:label "CB Granule Glut_2 cerebellar granule cell (Mmus)" ;
rdfs:comment "A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Gap43 (Mmus), Rab37 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1155 CB Granule Glut_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300354 .
obo:PR_P51683 a rdfs:Class ;
rdfs:label "C-C chemokine receptor type 2 (mouse)" ;
rdfs:comment "A C-C chemokine receptor type 2 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001199 , obo:PR_000029032 .
obo:GO_0036211 a rdfs:Class ;
rdfs:label "protein modification process" ;
rdfs:comment "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." ;
rdfs:subClassOf obo:GO_0019538 , obo:GO_0043412 .
obo:CHEBI_63951 a rdfs:Class ;
rdfs:label "estrogen receptor agonist" ;
rdfs:comment "An agonist at the estrogen receptor." ;
rdfs:subClassOf obo:CHEBI_48705 .
obo:GO_0060252 a rdfs:Class ;
rdfs:label "positive regulation of glial cell proliferation" ;
rdfs:comment "Any process that activates or increases the rate or extent of glial cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0014015 , obo:GO_0060251 , obo:GO_0065007 .
obo:CHEBI_35312 a rdfs:Class ;
rdfs:label "pentoside" ;
rdfs:subClassOf obo:CHEBI_24400 .
obo:GO_1903566 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to cilium" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to cilium." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903564 , obo:GO_1903829 .
obo:UBERON_0036146 a rdfs:Class ;
rdfs:label "cardiopharyngeal field" ;
rdfs:comment "An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0004120 , obo:UBERON_0005291 , obo:UBERON_0007688 .
obo:CHEBI_38101 a rdfs:Class ;
rdfs:label "organonitrogen heterocyclic compound" ;
rdfs:comment "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_35352 .
obo:GO_0010760 a rdfs:Class ;
rdfs:label "negative regulation of macrophage chemotaxis" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0002689 , obo:GO_0010758 , obo:GO_0065007 , obo:GO_1905522 .
obo:GO_0002720 a rdfs:Class ;
rdfs:label "positive regulation of cytokine production involved in immune response" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response." ;
rdfs:subClassOf obo:GO_0001819 , obo:GO_0002702 , obo:GO_0002718 , obo:GO_0065007 .
obo:UBERON_0000119 a rdfs:Class ;
rdfs:label "cell layer" ;
rdfs:comment "Portion of tissue, that consists of single layer of cells connected to each other by cell junctions. Examples: layer of glial cells; epithelium." ;
rdfs:subClassOf obo:UBERON_0000957 .
obo:GO_0048631 a rdfs:Class ;
rdfs:label "regulation of skeletal muscle tissue growth" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of skeletal muscle growth." ;
rdfs:subClassOf obo:GO_0048638 , obo:GO_0065007 .
obo:GO_0002763 a rdfs:Class ;
rdfs:label "positive regulation of myeloid leukocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation." ;
rdfs:subClassOf obo:GO_0002761 , obo:GO_0045639 , obo:GO_0065007 , obo:GO_1902107 .
obo:PHIPO_0001264 a rdfs:Class ;
rdfs:label "host physiological process affected by pathogen phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which a pathogen effects a change in the physiological processes of its host organism." ;
rdfs:subClassOf obo:PHIPO_0001173 .
obo:UBERON_8600123 a rdfs:Class ;
rdfs:label "lower airway ganglion" ;
rdfs:comment "A parasympathetic ganglion that is located within the airway walls of the lower respiratory tract. This ganglion is responsible for controlling the constriction of the airway by stimulating smooth muscle contraction in the lower respiratory tract to regulate airflow." ;
rdfs:subClassOf obo:UBERON_0001808 .
obo:UBERON_0004670 a rdfs:Class ;
rdfs:label "ependyma" ;
rdfs:comment "The thin epithelium-like membrane composed of ependymal cells that lines the ventricular system of the brain and the spinal cord." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0007601 , obo:UBERON_0010371 .
obo:GO_0004536 a rdfs:Class ;
rdfs:label "DNA nuclease activity" ;
rdfs:comment "Catalysis of the cleavage of ester linkages within deoxyribonucleic acid." ;
rdfs:subClassOf obo:GO_0004518 , obo:GO_0140097 .
obo:GO_0002696 a rdfs:Class ;
rdfs:label "positive regulation of leukocyte activation" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." ;
rdfs:subClassOf obo:GO_0002684 , obo:GO_0002694 , obo:GO_0050867 , obo:GO_0065007 .
obo:CHEBI_35720 a rdfs:Class ;
rdfs:label "enrofloxacin" ;
rdfs:comment "A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid substituted by an oxo group at position 4, a fluoro group at position 6, a cyclopropyl group at position 1 and a 4-ethylpiperazin-1-yl group at position 7. It is a veterinary antibacterial agent used for the treatment of pets." ;
rdfs:subClassOf obo:CHEBI_23765 , obo:CHEBI_26512 , obo:CHEBI_37143 , obo:CHEBI_46845 , obo:CHEBI_46848 , obo:CHEBI_51454 .
obo:PR_000001865 a rdfs:Class ;
rdfs:label "interleukin-3 receptor class 2 alpha chain" ;
rdfs:comment "A protein that is a translation product of the human IL3RA gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_22601 a rdfs:Class ;
rdfs:label "arabinoside" ;
rdfs:subClassOf obo:CHEBI_35312 .
obo:GO_2000647 a rdfs:Class ;
rdfs:label "negative regulation of stem cell proliferation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation." ;
rdfs:subClassOf obo:GO_0008285 , obo:GO_0065007 , obo:GO_0072091 .
obo:GO_0001773 a rdfs:Class ;
rdfs:label "myeloid dendritic cell activation" ;
rdfs:comment "The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0002274 .
obo:GO_0008092 a rdfs:Class ;
rdfs:label "cytoskeletal protein binding" ;
rdfs:comment "Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton)." ;
rdfs:subClassOf obo:GO_0005515 .
obo:UBERON_0036253 a rdfs:Class ;
rdfs:label "orifice of skull" ;
rdfs:subClassOf obo:UBERON_0000161 .
obo:GO_0021582 a rdfs:Class ;
rdfs:label "medulla oblongata maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:GO_0021618 a rdfs:Class ;
rdfs:label "hypoglossal nerve morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0021602 .
obo:PHIPO_0001413 a rdfs:Class ;
rdfs:label "normal growth on dalfopristin" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to dalfopristin (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_71644 a rdfs:Class ;
rdfs:label "lantibiotic" ;
rdfs:comment "A class of peptide antibiotic characterised by the presence of the rare thioether amino acids lanthionine or methyllanthionine, as well as the unsaturated amino acids dehydroalanine and 2-aminoisobutyric acid. In contrast to classical peptide antibiotics, lantibiotics are synthesised from precursor genes using the ribosomal pathway and the characteristic rare amino acids are introduced by posttranslational modification procedues into the lantibiotic precursor peptides ('prepeptides'). Lantibiotics are subdivided into two types: type A have long, flexible structures, while type B have rigid, globular structures." ;
rdfs:subClassOf obo:CHEBI_15841 , obo:CHEBI_25903 .
obo:GO_0043388 a rdfs:Class ;
rdfs:label "positive regulation of DNA binding" ;
rdfs:comment "Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)." ;
rdfs:subClassOf obo:GO_0051099 , obo:GO_0051101 , obo:GO_0065007 .
obo:GO_0000262 a rdfs:Class ;
rdfs:label "mitochondrial chromosome" ;
rdfs:comment "A chromosome found in the mitochondrion of a eukaryotic cell." ;
rdfs:subClassOf obo:GO_0005694 .
obo:GO_1901953 a rdfs:Class ;
rdfs:label "positive regulation of anterograde dense core granule transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1901610 , obo:GO_1901951 , obo:GO_1904811 .
obo:GO_0170039 a rdfs:Class ;
rdfs:label "proteinogenic amino acid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein." ;
rdfs:subClassOf obo:GO_0006520 , obo:GO_0008152 , obo:GO_0019752 .
obo:GO_0043031 a rdfs:Class ;
rdfs:label "negative regulation of macrophage activation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation." ;
rdfs:subClassOf obo:GO_0002695 , obo:GO_0043030 , obo:GO_0065007 .
obo:PHIPO_0000255 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction transport phenotype" ;
rdfs:comment "A pathogen host interaction (cell process???) phenotype that affects a transport process." .
obo:GO_0036179 a rdfs:Class ;
rdfs:label "osteoclast maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0048469 .
obo:PATO_0000141 a rdfs:Class ;
rdfs:label "structure" ;
rdfs:comment "A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:GO_1903180 a rdfs:Class ;
rdfs:label "negative regulation of dopamine biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0045963 , obo:GO_0065007 , obo:GO_1903179 .
obo:UBERON_0007005 a rdfs:Class ;
rdfs:label "cardiogenic splanchnic mesoderm" ;
rdfs:comment "The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]." ;
rdfs:subClassOf obo:UBERON_0005291 .
obo:CL_4300353 a rdfs:Class ;
rdfs:label "Purkinje cell (Mmus)" ;
rdfs:comment "A Purkinje cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pcp2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:313 CBX Purkinje Gaba." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000121 , obo:CL_4300028 .
obo:CHEBI_17489 a rdfs:Class ;
rdfs:label "3',5'-cyclic AMP" ;
rdfs:comment "A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase." ;
rdfs:subClassOf obo:CHEBI_19834 , obo:CHEBI_61296 .
obo:CL_0000681 a rdfs:Class ;
rdfs:label "radial glial cell" ;
rdfs:comment "A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration." ;
rdfs:subClassOf obo:CL_0000125 .
obo:GO_1903018 a rdfs:Class ;
rdfs:label "regulation of glycoprotein metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process." ;
rdfs:subClassOf obo:GO_0051246 , obo:GO_0065007 .
obo:CHEBI_76206 a rdfs:Class ;
rdfs:label "xenobiotic metabolite" ;
rdfs:comment "Any metabolite produced by metabolism of a xenobiotic compound." ;
rdfs:subClassOf obo:CHEBI_25212 .
obo:CHEBI_17089 a rdfs:Class .
obo:CL_4307069 a rdfs:Class ;
rdfs:label "beta1-tancyte (Mmus)" ;
rdfs:comment "A beta1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Frzb (Mmus), Foxd2os (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Col25a1, C230072F16Rik. These cells are located in the Hypothalamus, brain , in or close to the regions: third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5249 Tanycyte NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4042019 , obo:CL_4301603 .
obo:CHEBI_33570 a rdfs:Class ;
rdfs:label "benzenediols" ;
rdfs:subClassOf obo:CHEBI_33853 .
obo:GO_1901859 a rdfs:Class ;
rdfs:label "negative regulation of mitochondrial DNA metabolic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process." ;
rdfs:subClassOf obo:GO_0051053 , obo:GO_0065007 , obo:GO_1901858 .
obo:GO_0001826 a rdfs:Class ;
rdfs:label "inner cell mass cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_2000691 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle cell myoblast differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation." ;
rdfs:subClassOf obo:GO_0045662 , obo:GO_0051892 , obo:GO_0065007 , obo:GO_2000690 .
obo:CHEBI_9986 a rdfs:Class ;
rdfs:label "vinclozolin" ;
rdfs:comment "A racemate comprising equimolar amounts of (R)- and (S)-vinclozolin. A fungicide used mainly on oilseed rape, vines, fruit and vegetables to control Botrytis, Sclerotinia and Monilia spp." ;
rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87197 .
obo:GO_0002440 a rdfs:Class ;
rdfs:label "production of molecular mediator of immune response" ;
rdfs:comment "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0010467 .
obo:GO_0044848 a rdfs:Class ;
rdfs:label "biological phase" ;
rdfs:comment "A distinct period or stage in a biological process or cycle." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CL_0000362 a rdfs:Class ;
rdfs:label "epidermal cell" ;
rdfs:comment "An epithelial cell of the integument (the outer layer of an organism)." ;
rdfs:subClassOf obo:CL_0000066 , obo:CL_0002159 .
obo:PHIPO_0000571 a rdfs:Class ;
rdfs:label "resistance to leptomycin B"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to leptomycin B. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0001739 a rdfs:Class ;
rdfs:label "sex chromatin" ;
rdfs:comment "Chromatin that is part of a sex chromosome." ;
rdfs:subClassOf obo:GO_0000792 .
obo:PHIPO_0001408 a rdfs:Class ;
rdfs:label "resistance to iprovalicarb" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to iprovalicarb. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0002735 a rdfs:Class ;
rdfs:label "positive regulation of myeloid dendritic cell cytokine production" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production." ;
rdfs:subClassOf obo:GO_0002732 , obo:GO_0002733 , obo:GO_0002888 , obo:GO_0061081 , obo:GO_0065007 .
obo:UBERON_0010046 a rdfs:Class ;
rdfs:label "entire pharyngeal arch associated mesenchyme" ;
rdfs:comment "The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells." ;
rdfs:subClassOf obo:UBERON_0005291 , obo:UBERON_0007524 .
obo:PR_000001003 a rdfs:Class ;
rdfs:label "CD34 molecule" ;
rdfs:comment "A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CHEBI_23239 a rdfs:Class ;
rdfs:label "chromopeptide" ;
rdfs:subClassOf obo:CHEBI_25903 .
obo:GO_0060684 a rdfs:Class ;
rdfs:label "epithelial-mesenchymal cell signaling" ;
rdfs:comment "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted." ;
rdfs:subClassOf obo:GO_0007267 .
obo:UBERON_0004711 a rdfs:Class ;
rdfs:label "jugular vein" ;
rdfs:comment "The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:PHIPO_0000826 a rdfs:Class ;
rdfs:label "sensitive to ticarcillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ticarcillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:UBERON_0003258 a rdfs:Class ;
rdfs:label "endoderm of foregut" ;
rdfs:comment "An endoderm that is part of a foregut [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0005911 , obo:UBERON_0015833 .
obo:PHIPO_0000979 a rdfs:Class ;
rdfs:label "sensitive to dithiothreitol"@en ;
rdfs:comment "A phenotype in which a population of a single-species shows increased sensitivity to 1,4-dithiothreitol (DTT), manifested as an affect on the extent of population growth. (CHEBI:18320)." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PATO_0000963 a rdfs:Class ;
rdfs:label "opaque" ;
rdfs:comment "A optical quality inhering in a bearer by virtue of the bearer's not being clear; not transmitting or reflecting light or radiant energy." ;
rdfs:subClassOf obo:PATO_0000957 .
obo:CHEBI_32544 a rdfs:Class ;
rdfs:label "nicotinate" ;
rdfs:comment "A pyridinemonocarboxylate that is the conjugate base of nicotinic acid, arising from deprotonation of the carboxy group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_176839 , obo:CHEBI_38181 .
obo:CHEBI_50658 a rdfs:Class ;
rdfs:label "ampicillin(1-)" ;
rdfs:subClassOf obo:CHEBI_51356 .
obo:UBERON_0009584 a rdfs:Class ;
rdfs:label "1st arch mandibular mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a 1st arch mandibular component." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0010042 .
obo:UBERON_0002012 a rdfs:Class ;
rdfs:label "pulmonary artery" ;
rdfs:comment "An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.." ;
rdfs:subClassOf obo:UBERON_0001637 , obo:UBERON_0013768 .
obo:GO_0005811 a rdfs:Class ;
rdfs:label "lipid droplet" ;
rdfs:comment "An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins." ;
rdfs:subClassOf obo:GO_0043232 .
obo:GO_0040008 a rdfs:Class ;
rdfs:label "regulation of growth" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:PHIPO_0000939 a rdfs:Class ;
rdfs:label "asexual spore lysis absent"@en ;
rdfs:comment "An single species phenotype in which an asexual spore does not lyse, i.e. the plasma membrane ruptures and cytoplasm is lost." ;
rdfs:subClassOf obo:PHIPO_0000936 .
obo:CHEBI_38164 a rdfs:Class ;
rdfs:label "organic heteropentacyclic compound" ;
rdfs:subClassOf obo:CHEBI_38166 .
obo:PHIPO_0000151 a rdfs:Class ;
rdfs:label "abnormal multiple protein binding to DNA"@en ;
rdfs:comment "A single organism (molecular function??) phenotype in which the binding of two or more proteins to DNA is abnormal. The proteins may bind simultaneously or sequentially, but both or all would normally be present together on DNA at some time. One affected gene product may be encoded by the mutated gene, or all may be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000145 .
obo:UBERON_0002093 a rdfs:Class ;
rdfs:label "spinal dura mater" ;
rdfs:comment "A dura mater that is part of a spinal cord [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002363 , obo:UBERON_0003292 .
obo:GO_0031410 a rdfs:Class ;
rdfs:label "cytoplasmic vesicle" ;
rdfs:comment "A vesicle found in the cytoplasm of a cell." ;
rdfs:subClassOf obo:GO_0031982 , obo:GO_0097708 .
obo:CHEBI_136622 a rdfs:Class ;
rdfs:label "aci-nitro compound" ;
rdfs:comment "Organonitrogen compounds that have the general structure R1(R2)C=N(O)OH (R1,R2 = H, organyl). They are tautomers of C-nitro compounds." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:CL_4301574 a rdfs:Class ;
rdfs:label "CB PLI Gly-Gaba_1 Purkinje layer interneuron (Mmus)" ;
rdfs:comment "A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Hmga2 (Mmus), Afap1l2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1144 CB PLI Gly-Gaba_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300349 .
obo:GO_1903038 a rdfs:Class ;
rdfs:label "negative regulation of leukocyte cell-cell adhesion" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion." ;
rdfs:subClassOf obo:GO_0022408 , obo:GO_0065007 , obo:GO_1903037 .
obo:UBERON_0003697 a rdfs:Class ;
rdfs:label "abdominal wall" ;
rdfs:comment "The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles." ;
rdfs:subClassOf obo:UBERON_0000060 .
obo:PATO_0002254 a rdfs:Class ;
rdfs:label "flattened" ;
rdfs:comment "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." ;
rdfs:subClassOf obo:PATO_0001591 .
obo:CL_0000040 a rdfs:Class ;
rdfs:label "monoblast" ;
rdfs:comment "A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus." ;
rdfs:subClassOf obo:CL_0000763 , obo:CL_0002194 .
obo:GO_0098723 a rdfs:Class ;
rdfs:label "skeletal muscle myofibril" ;
rdfs:comment "A myofibril of a skeletal muscle fiber." ;
rdfs:subClassOf obo:GO_0030016 .
obo:UBERON_0005865 a rdfs:Class ;
rdfs:label "pre-muscle condensation" ;
rdfs:subClassOf obo:UBERON_0005856 .
obo:PHIPO_0000285 a rdfs:Class ;
rdfs:label "abnormal cellular pigment accumulation"@en ;
rdfs:comment "A single species individual organism phenotype where the accumulation of coloring matter in a cell is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000284 .
obo:GO_0050658 a rdfs:Class ;
rdfs:label "RNA transport" ;
rdfs:comment "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0050657 , obo:GO_0051236 .
obo:CL_4310058 a rdfs:Class ;
rdfs:label "STR D1 MSN direct pathway medium spiny neuron (Primate)" ;
rdfs:comment "A direct pathway medium spiny neuron of the Primates brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Subclass:STR D1 MSN." ;
rdfs:subClassOf obo:CL_4023026 .
obo:PHIPO_0000880 a rdfs:Class ;
rdfs:label "sensitive to sulfisoxazole"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulfisoxazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_75929 a rdfs:Class ;
rdfs:label "D-cycloserine(1+)" ;
rdfs:comment "An organic cation that is the conjugate acid of D-cycloserine, obtained by protonation of the amino group." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:PR_Q62351 a rdfs:Class ;
rdfs:label "transferrin receptor protein 1 (mouse)" ;
rdfs:comment "A transferrin receptor protein 1 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001945 , obo:PR_000029032 .
obo:CHEBI_25213 a rdfs:Class ;
rdfs:label "metal cation" ;
rdfs:subClassOf obo:CHEBI_23906 , obo:CHEBI_36915 .
obo:PHIPO_0000389 a rdfs:Class ;
rdfs:label "resistance to iprodione"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to iprodione. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0004733 a rdfs:Class ;
rdfs:label "segmental subdivision of hindbrain" ;
rdfs:comment "An organ subunit that is part of a hindbrain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000063 , obo:UBERON_0004732 .
obo:PHIPO_0001289 a rdfs:Class ;
rdfs:label "sensitive to tolnaftate"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to tolnaftate. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0036242 a rdfs:Class ;
rdfs:label "post-embryonic notochord" ;
rdfs:comment "A notochord that has persisted beyond the embryonic stage." ;
rdfs:subClassOf obo:UBERON_0002328 .
obo:GO_0061056 a rdfs:Class ;
rdfs:label "sclerotome development" ;
rdfs:comment "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060485 .
obo:GO_0006629 a rdfs:Class ;
rdfs:label "lipid metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0044238 .
obo:GO_0044207 a rdfs:Class ;
rdfs:label "translation initiation ternary complex" ;
rdfs:comment "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." ;
rdfs:subClassOf obo:GO_1990904 .
obo:CL_0000351 a rdfs:Class ;
rdfs:label "trophoblast cell" ;
rdfs:comment "An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development." ;
rdfs:subClassOf obo:CL_0000349 .
obo:GO_1905430 a rdfs:Class ;
rdfs:label "cellular response to glycine" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_0071230 , obo:GO_1901699 , obo:GO_1901701 , obo:GO_1905429 .
obo:GO_0038161 a rdfs:Class ;
rdfs:label "prolactin signaling pathway" ;
rdfs:comment "The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription." ;
rdfs:subClassOf obo:GO_0009755 , obo:GO_0019221 .
obo:GO_0010771 a rdfs:Class ;
rdfs:label "negative regulation of cell morphogenesis" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0022604 , obo:GO_0065007 .
obo:PR_000025796 a rdfs:Class ;
rdfs:label "integrin alpha" ;
rdfs:comment "A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:GO_1904705 a rdfs:Class ;
rdfs:label "regulation of vascular associated smooth muscle cell proliferation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation." ;
rdfs:subClassOf obo:GO_0048660 , obo:GO_0065007 .
obo:GO_0010764 a rdfs:Class ;
rdfs:label "negative regulation of fibroblast migration" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." ;
rdfs:subClassOf obo:GO_0010762 , obo:GO_0030336 , obo:GO_0065007 .
obo:CHEBI_63247 a rdfs:Class ;
rdfs:label "reducing agent" ;
rdfs:comment "The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:CHEBI_2580 a rdfs:Class ;
rdfs:label "unsaturated fatty acid anion" ;
rdfs:comment "Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:PHIPO_0001204 a rdfs:Class ;
rdfs:label "decreased extent of host-defense induced lesion by host hypersensitive response"@en ;
rdfs:comment "A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense to a lesser extent than normal." ;
rdfs:subClassOf obo:PHIPO_0000192 , obo:PHIPO_0000985 .
obo:GO_0140053 a rdfs:Class ;
rdfs:label "mitochondrial gene expression" ;
rdfs:comment "The process of transcribing and translating the mitochondrial genome (mtDNA) to produce at least a subset of oxidative phosphorylation (OXPHOS) proteins, 2 rRNAs, and mitochondrial tRNAs, which are critical for ATP production. Protein maturation is included when required to form an active form of a product from an inactive precursor form." ;
rdfs:subClassOf obo:GO_0010467 .
obo:CHEBI_76764 a rdfs:Class ;
rdfs:label "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor" ;
rdfs:comment "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." ;
rdfs:subClassOf obo:CHEBI_76759 .
obo:GO_0140353 a rdfs:Class ;
rdfs:label "lipid export from cell" ;
rdfs:comment "The directed movement of a lipid from a cell, into the extracellular region." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0006869 , obo:GO_0140352 .
obo:GO_0003208 a rdfs:Class ;
rdfs:label "cardiac ventricle morphogenesis" ;
rdfs:comment "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." ;
rdfs:subClassOf obo:GO_0003206 , obo:GO_0009653 .
obo:CHEBI_59698 a rdfs:Class ;
rdfs:label "phosphoric acids" ;
rdfs:comment "Compounds containing one or more phosphoric acid units." ;
rdfs:subClassOf obo:CHEBI_33457 .
obo:CHEBI_23888 a rdfs:Class ;
rdfs:label "drug" ;
rdfs:comment "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." ;
rdfs:subClassOf obo:CHEBI_52217 .
obo:CHEBI_37577 a rdfs:Class ;
rdfs:label "heteroatomic molecular entity" ;
rdfs:comment "A molecular entity consisting of two or more chemical elements." ;
rdfs:subClassOf obo:CHEBI_36357 .
obo:GO_0050806 a rdfs:Class ;
rdfs:label "positive regulation of synaptic transmission" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." ;
rdfs:subClassOf obo:GO_0010647 , obo:GO_0023056 , obo:GO_0050804 , obo:GO_0065007 .
obo:GO_0043242 a rdfs:Class ;
rdfs:label "negative regulation of protein-containing complex disassembly" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ;
rdfs:subClassOf obo:GO_0043244 , obo:GO_0051129 , obo:GO_0065007 .
obo:UBERON_0010359 a rdfs:Class ;
rdfs:label "pharyngeal arch mesenchyme from neural crest" ;
rdfs:comment "Mesenchyme that develops_from a neural crest and is part of a entire pharyngeal arch associated mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0005291 , obo:UBERON_0014387 .
obo:GO_0003676 a rdfs:Class ;
rdfs:label "nucleic acid binding" ;
rdfs:comment "Binding to a nucleic acid." ;
rdfs:subClassOf obo:GO_0005488 .
obo:CHEBI_87195 a rdfs:Class ;
rdfs:label "dicarboximide fungicide" ;
rdfs:comment "Any dicarboximide antifungal agent used as a fungicide." ;
rdfs:subClassOf obo:CHEBI_87200 .
obo:CL_0000077 a rdfs:Class ;
rdfs:label "mesothelial cell" ;
rdfs:comment "A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement." ;
rdfs:subClassOf obo:CL_0000076 , obo:CL_0002078 .
obo:CL_4040004 a rdfs:Class ;
rdfs:label "mesenchymal stem cell of orbital adipose tissue" ;
rdfs:comment "Any mesenchymal stem cell of adipose tissue that is part of an orbital region." ;
rdfs:subClassOf obo:CL_0002570 .
obo:CL_2000080 a rdfs:Class ;
rdfs:label "mesenchymal stem cell of abdominal adipose tissue" ;
rdfs:comment "Any mesenchymal stem cell of adipose tissue that is part of an abdomen." ;
rdfs:subClassOf obo:CL_0002570 .
obo:GO_0051667 a rdfs:Class ;
rdfs:label "establishment of plastid localization" ;
rdfs:comment "The directed movement of a plastid to a specific location in the cell." ;
rdfs:subClassOf obo:GO_0051234 , obo:GO_0051644 , obo:GO_0051649 , obo:GO_0051656 .
obo:CHEBI_50160 a rdfs:Class ;
rdfs:label "steroid acid anion" ;
rdfs:comment "Any anion formed by loss of a proton from a steroid acid." ;
rdfs:subClassOf obo:CHEBI_29067 .
obo:GO_0060427 a rdfs:Class ;
rdfs:label "lung connective tissue development" ;
rdfs:comment "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0061448 .
obo:UBERON_8600006 a rdfs:Class ;
rdfs:label "visceral striated muscle tissue" ;
rdfs:comment "A striated muscle tissue that is associated with soft internal organs (viscera)." ;
rdfs:subClassOf obo:UBERON_0002036 , obo:UBERON_8600004 .
obo:PHIPO_0001331 a rdfs:Class ;
rdfs:label "normal growth on procymidone"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to procymidone (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_1905312 a rdfs:Class ;
rdfs:label "positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." ;
rdfs:subClassOf obo:GO_0030335 , obo:GO_0065007 , obo:GO_1905310 .
obo:PHIPO_0000196 a rdfs:Class ;
rdfs:label "normal aerial height of filament"@en ;
rdfs:comment "An individual organism growth phenotype in which the aerial height of hyphae is normal (indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001210 .
obo:UBERON_0001027 a rdfs:Class ;
rdfs:label "sensory nerve" ;
rdfs:comment "A nerve that transmits from sensory receptors on the surface of the body to the central nervous system." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:GO_0003236 a rdfs:Class ;
rdfs:label "sinus venosus morphogenesis" ;
rdfs:comment "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." ;
rdfs:subClassOf obo:GO_0003206 , obo:GO_0009653 .
obo:GO_1904956 a rdfs:Class ;
rdfs:label "regulation of midbrain dopaminergic neuron differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904338 .
obo:CHEBI_28098 a rdfs:Class ;
rdfs:label "kanamycin B" ;
rdfs:subClassOf obo:CHEBI_24951 , obo:CHEBI_61689 .
obo:CHEBI_83761 a rdfs:Class ;
rdfs:label "(2R,3S)-epoxiconazole" ;
rdfs:comment "The (2R,3S)-stereoisomer of 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole." ;
rdfs:subClassOf obo:CHEBI_83758 .
obo:UBERON_0003509 a rdfs:Class ;
rdfs:label "arterial blood vessel" ;
rdfs:comment "A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:GO_0007028 a rdfs:Class ;
rdfs:label "cytoplasm organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." ;
rdfs:subClassOf obo:GO_0016043 .
obo:CHEBI_77054 a rdfs:Class ;
rdfs:label "N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide" ;
rdfs:comment "An aromatic amide resulting from the formal condensation of the carboxy group of 3,5-diiodosalicylic acid with the amino group of aniline substituted at positions 2, 4, and 5 by methyl, (4-chlorophenyl)(cyano)methyl, and methyl groups respectively." ;
rdfs:subClassOf obo:CHEBI_18379 , obo:CHEBI_29347 , obo:CHEBI_33853 , obo:CHEBI_37142 , obo:CHEBI_62733 , obo:CHEBI_83403 .
obo:CHEBI_61007 a rdfs:Class ;
rdfs:label "amino fatty acid anion" ;
rdfs:comment "A nitrogen-containing fatty acid anion arising from deprotonation of the carboxy group of any amino fatty acid." ;
rdfs:subClassOf obo:CHEBI_37022 , obo:CHEBI_61008 .
obo:GO_0010455 a rdfs:Class ;
rdfs:label "positive regulation of cell fate commitment" ;
rdfs:comment "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ;
rdfs:subClassOf obo:GO_0010453 , obo:GO_0045597 , obo:GO_0065007 .
obo:UBERON_0005690 a rdfs:Class ;
rdfs:label "3rd arch mesenchyme" ;
rdfs:comment "Mesenchyme that is part of a pharyngeal arch 3." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0009494 .
obo:UBERON_0010528 a rdfs:Class ;
rdfs:label "pneumatic cavity of bone" ;
rdfs:subClassOf obo:UBERON_0010527 .
obo:GO_0023019 a rdfs:Class ;
rdfs:label "signal transduction involved in regulation of gene expression" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." ;
rdfs:subClassOf obo:GO_0007165 .
obo:GO_0051630 a rdfs:Class ;
rdfs:label "acetylcholine uptake" ;
rdfs:comment "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0015870 .
obo:GO_0060897 a rdfs:Class ;
rdfs:label "neural plate regionalization" ;
rdfs:comment "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." ;
rdfs:subClassOf obo:GO_0003002 , obo:GO_0060896 .
obo:UBERON_0001190 a rdfs:Class ;
rdfs:label "ovarian artery" ;
rdfs:comment "An artery that supplies an ovary." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:PHIPO_0001112 a rdfs:Class ;
rdfs:label "obsolete normal pH within a pathogen host interaction" ;
rdfs:comment "A pathogen host interaction phenotype where the pH in a pathogen or host cell or cellular component is normal." .
obo:GO_0046826 a rdfs:Class ;
rdfs:label "negative regulation of protein export from nucleus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0046823 , obo:GO_0046825 , obo:GO_0051457 , obo:GO_0065007 , obo:GO_0090317 .
obo:UBERON_0001616 a rdfs:Class ;
rdfs:label "maxillary artery" ;
rdfs:comment "An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:CL_0000521 a rdfs:Class ;
rdfs:label "fungal cell" ;
rdfs:comment "Any cell that in taxon some Fungi." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000255 .
obo:GO_0098916 a rdfs:Class ;
rdfs:label "anterograde trans-synaptic signaling" ;
rdfs:comment "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." ;
rdfs:subClassOf obo:GO_0099537 .
obo:PHIPO_0001350 a rdfs:Class ;
rdfs:label "normal growth on pyrifenox" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrifenox (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:CHEBI_50312 a rdfs:Class ;
rdfs:label "onium compound" ;
rdfs:subClassOf obo:CHEBI_37577 .
obo:UBERON_0005250 a rdfs:Class ;
rdfs:label "stomatodeum gland" ;
rdfs:comment "A gland that is part of a stomodeum." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:GO_0065007 a rdfs:Class ;
rdfs:label "biological regulation" ;
rdfs:comment "Any process that modulates a measurable attribute of any biological process, quality or function." ;
rdfs:subClassOf obo:GO_0008150 .
obo:CHEBI_23217 a rdfs:Class ;
rdfs:label "cholines" ;
rdfs:comment "A quaternary ammonium ion based on the choline ion and its substituted derivatives thereof." ;
rdfs:subClassOf obo:CHEBI_35267 .
obo:GO_0032879 a rdfs:Class ;
rdfs:label "regulation of localization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:UBERON_0003528 a rdfs:Class ;
rdfs:label "brain gray matter" ;
rdfs:comment "A gray matter that is part of a brain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002020 .
obo:UBERON_0022318 a rdfs:Class ;
rdfs:label "olfactory cortex layer 2" ;
rdfs:comment "Middle layer of olfactory cortex lying deep to layer 1 and superficial to layer 3, characterized by a compact layer of cell bodies. It can be divided into a superficial part and a deep part." ;
rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0022303 .
obo:CL_4310100 a rdfs:Class ;
rdfs:label "GPe-NDB-SI LHX6-LHX8-GBX1 GABA GABAergic interneuron (Primate)" ;
rdfs:comment "A GABAergic interneuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe-NDB-SI LHX6-LHX8-GBX1 GABA." ;
rdfs:subClassOf obo:CL_0011005 .
obo:CHEBI_34998 a rdfs:Class ;
rdfs:label "teicoplanin A2-5" ;
rdfs:comment "A teicoplanin A2 that has 9-methyldecanoyl as the variable N-acyl group." ;
rdfs:subClassOf obo:CHEBI_34994 .
obo:UBERON_0004495 a rdfs:Class ;
rdfs:label "skeletal muscle tissue of diaphragm" ;
rdfs:comment "A portion of skeletal muscle tissue that is part of a diaphragm [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001134 , obo:UBERON_0003898 , obo:UBERON_0004830 .
obo:CHEBI_37175 a rdfs:Class ;
rdfs:label "organic hydride" ;
rdfs:subClassOf obo:CHEBI_33692 .
obo:PHIPO_0000046 a rdfs:Class ;
rdfs:label "normal sexual reproduction"@en ;
rdfs:comment "A single species phenotype where the sexual reproduction process in which new individuals are produced by combining the genetic material of two gametes, which may come from two organisms or from a single organism is normal (indistinguishable from wild type) (GO:0019953)." ;
rdfs:subClassOf obo:PHIPO_0000044 .
obo:GO_0030397 a rdfs:Class ;
rdfs:label "membrane disassembly" ;
rdfs:comment "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." ;
rdfs:subClassOf obo:GO_0022411 , obo:GO_0061024 .
obo:GO_0014005 a rdfs:Class ;
rdfs:label "microglia development" ;
rdfs:comment "The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0021782 , obo:GO_0032502 , obo:GO_0061515 .
obo:GO_0030218 a rdfs:Class ;
rdfs:label "erythrocyte differentiation" ;
rdfs:comment "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte." ;
rdfs:subClassOf obo:GO_0030099 , obo:GO_0030154 .
obo:UBERON_0001041 a rdfs:Class ;
rdfs:label "foregut" ;
rdfs:comment "Anterior subdivision of a digestive tract." ;
rdfs:subClassOf obo:UBERON_0004921 .
obo:CL_0000066 a rdfs:Class ;
rdfs:label "epithelial cell" ;
rdfs:comment "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." ;
rdfs:subClassOf obo:CL_0000255 .
obo:PHIPO_0001163 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction reproductive phenotype" ;
rdfs:comment "A pathogen host interaction phenotype which affects either the pathogen or host reproductive process. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003)." .
obo:GO_0065002 a rdfs:Class ;
rdfs:label "intracellular protein transmembrane transport" ;
rdfs:comment "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0006886 , obo:GO_0055085 , obo:GO_0071806 .
obo:GO_0002087 a rdfs:Class ;
rdfs:label "regulation of respiratory gaseous exchange by nervous system process" ;
rdfs:comment "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates." ;
rdfs:subClassOf obo:GO_0044065 , obo:GO_0050877 .
obo:CHEBI_60334 a rdfs:Class ;
rdfs:label "peptide anion" ;
rdfs:comment "An anion formed by deprotonation of at least one peptide carboxy group." ;
rdfs:subClassOf obo:CHEBI_25696 .
obo:CHEBI_50248 a rdfs:Class ;
rdfs:label "hematologic agent" ;
rdfs:comment "Drug that acts on blood and blood-forming organs and those that affect the hemostatic system." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:UBERON_0003297 a rdfs:Class ;
rdfs:label "gland of integumental system" ;
rdfs:comment "A gland that is part of a integumental system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:CHEBI_5280 a rdfs:Class ;
rdfs:label "gatifloxacin" ;
rdfs:comment "A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes." ;
rdfs:subClassOf obo:CHEBI_23765 , obo:CHEBI_26512 , obo:CHEBI_37143 , obo:CHEBI_46848 , obo:CHEBI_60911 , obo:CHEBI_86324 .
obo:PATO_0002487 a rdfs:Class ;
rdfs:label "single organismal process quality" ;
rdfs:comment "A quality inhering in a process by virtue of that process having exactly one organism as a participant." ;
rdfs:subClassOf obo:PATO_0001236 .
obo:GO_0051649 a rdfs:Class ;
rdfs:label "establishment of localization in cell" ;
rdfs:comment "Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." ;
rdfs:subClassOf obo:GO_0051234 .
obo:CHEBI_76807 a rdfs:Class ;
rdfs:label "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor" ;
rdfs:comment "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." ;
rdfs:subClassOf obo:CHEBI_76764 .
obo:GO_0051249 a rdfs:Class ;
rdfs:label "regulation of lymphocyte activation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of lymphocyte activation." ;
rdfs:subClassOf obo:GO_0002694 , obo:GO_0065007 .
obo:UBERON_0004778 a rdfs:Class ;
rdfs:label "larynx submucosa" ;
rdfs:comment "A submucosa that is part of a larynx [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000009 , obo:UBERON_0004777 .
obo:GO_0051099 a rdfs:Class ;
rdfs:label "positive regulation of binding" ;
rdfs:comment "Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf obo:GO_0044093 , obo:GO_0051098 , obo:GO_0065007 .
obo:CHEBI_8434 a rdfs:Class ;
rdfs:label "prochloraz" ;
rdfs:comment "A member of the class of ureas that is 1H-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables." ;
rdfs:subClassOf obo:CHEBI_27096 , obo:CHEBI_35618 , obo:CHEBI_47857 , obo:CHEBI_60600 , obo:CHEBI_87067 , obo:CHEBI_87068 .
obo:CHEBI_39221 a rdfs:Class ;
rdfs:label "macrolide pesticide" ;
rdfs:subClassOf obo:CHEBI_25105 .
obo:GO_2000458 a rdfs:Class ;
rdfs:label "regulation of astrocyte chemotaxis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of astrocyte chemotaxis." ;
rdfs:subClassOf obo:GO_0050920 , obo:GO_0065007 , obo:GO_1903975 .
obo:UBERON_0001515 a rdfs:Class ;
rdfs:label "thoracic aorta" ;
rdfs:comment "The part of the aorta that extends from the origin at the heart to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest." ;
rdfs:subClassOf obo:UBERON_0005800 .
obo:UBERON_0004119 a rdfs:Class ;
rdfs:label "endoderm-derived structure" ;
rdfs:comment "An anatomical structure that develops (entirely or partially) from the endoderm." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:UBERON_0005056 a rdfs:Class ;
rdfs:label "external female genitalia" ;
rdfs:comment "An external genitalia that is part of a female reproductive system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003134 , obo:UBERON_0004176 .
obo:PHIPO_0001246 a rdfs:Class ;
rdfs:label "host PAMP-triggered immunity activated by pathogen present"@en ;
rdfs:comment "A phenotype where the process of pathogen-associated molecular pattern (PAMPs) or microbe-associated molecular pattern (MAMPs), activate the host PAMP-triggered immunity (PTI) innate immune system to trigger host defense responses such as reactive oxygen species (ROS) and callose deposition is present. (PAMPs and MAMPs are conserved structures among microbial species, eg chitin and lipopolysaccharide (LPS))." ;
rdfs:subClassOf obo:PHIPO_0001167 .
obo:CHEBI_32846 a rdfs:Class ;
rdfs:label "serinium" ;
rdfs:comment "An α-amino-acid cation that is the conjugate acid of serine." ;
rdfs:subClassOf obo:CHEBI_33719 .
obo:CHEBI_35350 a rdfs:Class ;
rdfs:label "hydroxy steroid" ;
rdfs:subClassOf obo:CHEBI_33822 , obo:CHEBI_35341 .
obo:GO_0045177 a rdfs:Class ;
rdfs:label "apical part of cell" ;
rdfs:comment "The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_1903848 a rdfs:Class ;
rdfs:label "negative regulation of aorta morphogenesis" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903847 , obo:GO_1905652 .
obo:GO_0051276 a rdfs:Class ;
rdfs:label "chromosome organization" ;
rdfs:comment "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0016043 .
obo:GO_0050863 a rdfs:Class ;
rdfs:label "regulation of T cell activation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of T cell activation." ;
rdfs:subClassOf obo:GO_0051249 , obo:GO_0065007 .
obo:CL_4042001 a rdfs:Class ;
rdfs:label "TAC3-positive striatal interneuron"@en ;
rdfs:comment "A GABAergic interneuron that has its soma located in the striatum and that has an enriched expression of the genes TAC3 and LHX6." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_0011005 .
a rdfs:Class ;
rdfs:label "Cerebellar cortex, Purkinje layer" ;
rdfs:subClassOf , obo:UBERON_0002979 .
obo:GO_0060467 a rdfs:Class ;
rdfs:label "negative regulation of fertilization" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0080154 , obo:GO_2000242 .
obo:UBERON_0003382 a rdfs:Class ;
rdfs:label "cardiac muscle of left ventricle" ;
rdfs:comment "A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001133 , obo:UBERON_0018649 .
obo:CL_4307133 a rdfs:Class ;
rdfs:label "BAM NN_1 Mrc1 border associated macrophage (Mmus)" ;
rdfs:comment "A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Pf4 (Mmus). It is distinguished from other BAM NN cells by expression of Mrc1, Pf4. These cells are located in the Medulla, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5313 BAM NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301625 .
obo:UBERON_0002079 a rdfs:Class ;
rdfs:label "left cardiac atrium" ;
rdfs:comment "A cardiac atrium that is in the left side of the heart. It receives oxygenated blood from the pulmonary veins, In mammals this is pumped into the left ventricle, via the Mitral valve." ;
rdfs:subClassOf obo:UBERON_0002081 , obo:UBERON_0035553 .
obo:UBERON_1000021 a rdfs:Class ;
rdfs:label "skin of face" ;
rdfs:comment "A zone of skin that is part of the face." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0001084 .
obo:GO_0061344 a rdfs:Class ;
rdfs:label "regulation of cell adhesion involved in heart morphogenesis" ;
rdfs:comment "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart." ;
rdfs:subClassOf obo:GO_0030155 , obo:GO_0065007 .
obo:UBERON_0005902 a rdfs:Class ;
rdfs:label "occipital region" ;
rdfs:comment "Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles." ;
rdfs:subClassOf obo:UBERON_0034921 .
obo:UBERON_0014704 a rdfs:Class ;
rdfs:label "pleuroperitoneal canal lumen" ;
rdfs:comment "An anatomical space that is enclosed by a pleuroperitoneal canal." ;
rdfs:subClassOf obo:UBERON_0000464 .
obo:CHEBI_26888 a rdfs:Class ;
rdfs:label "tetrachlorobenzene" ;
rdfs:comment "Any member of the class of chlorobenzenes carrying four chloro groups at unspecified positions." ;
rdfs:subClassOf obo:CHEBI_23132 .
obo:PHIPO_0000632 a rdfs:Class ;
rdfs:label "resistance to hydrogen peroxide"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to hydrogen peroxide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001342 a rdfs:Class ;
rdfs:label "resistance to triflumizole" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to triflumizole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0004178 a rdfs:Class ;
rdfs:label "aorta smooth muscle tissue" ;
rdfs:comment "The nonstriated, involuntary muscle tissue located in the wall of the aorta." ;
rdfs:subClassOf obo:UBERON_0001135 , obo:UBERON_0004237 , obo:UBERON_0004695 .
obo:PHIPO_0000428 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host interaction pathogen carbohydrate binding phenotype" .
obo:GO_2000272 a rdfs:Class ;
rdfs:label "negative regulation of signaling receptor activity" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity." ;
rdfs:subClassOf obo:GO_0010469 , obo:GO_0044092 , obo:GO_0065007 .
obo:GO_0045822 a rdfs:Class ;
rdfs:label "negative regulation of heart contraction" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction." ;
rdfs:subClassOf obo:GO_0008016 , obo:GO_0065007 , obo:GO_1903523 .
obo:CHEBI_60242 a rdfs:Class ;
rdfs:label "monovalent inorganic cation" ;
rdfs:comment "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." ;
rdfs:subClassOf obo:CHEBI_36915 .
obo:CHEBI_25442 a rdfs:Class ;
rdfs:label "mycotoxin" ;
rdfs:comment "Poisonous substance produced by fungi." ;
rdfs:subClassOf obo:CHEBI_27026 , obo:CHEBI_76946 .
obo:CHEBI_36343 a rdfs:Class ;
rdfs:label "composite particle" ;
rdfs:comment "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." ;
rdfs:subClassOf obo:CHEBI_36342 .
obo:GO_0046672 a rdfs:Class ;
rdfs:label "positive regulation of compound eye retinal cell programmed cell death" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." ;
rdfs:subClassOf obo:GO_0046669 , obo:GO_0046670 , obo:GO_0065007 .
obo:GO_1903115 a rdfs:Class ;
rdfs:label "regulation of actin filament-based movement" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of actin filament-based movement." ;
rdfs:subClassOf obo:GO_0032970 , obo:GO_0065007 .
obo:GO_0046394 a rdfs:Class ;
rdfs:label "carboxylic acid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0016053 , obo:GO_0019752 .
obo:PHIPO_0001286 a rdfs:Class ;
rdfs:label "presence of pathogen protein host DNA interaction"@en ;
rdfs:comment "A molecular function phenotype in which the binding of one pathogen protein to host DNA is present." ;
rdfs:subClassOf obo:PHIPO_0000164 .
obo:GO_0001885 a rdfs:Class ;
rdfs:label "endothelial cell development" ;
rdfs:comment "The progression of an endothelial cell over time, from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0002064 , obo:GO_0032502 .
obo:CHEBI_38597 a rdfs:Class ;
rdfs:label "triazole" ;
rdfs:subClassOf obo:CHEBI_35555 , obo:CHEBI_35727 .
obo:CHEBI_59871 a rdfs:Class ;
rdfs:label "D-alpha-amino acid zwitterion" ;
rdfs:comment "Zwitterionic form of a D-α-amino acid having an anionic carboxy group and a protonated amino group." ;
rdfs:subClassOf obo:CHEBI_35238 .
obo:GO_1905385 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to presynapse" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903828 , obo:GO_1905384 .
obo:UBERON_0001703 a rdfs:Class ;
rdfs:label "neurocranium" ;
rdfs:comment "Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof." ;
rdfs:subClassOf obo:UBERON_0011158 .
obo:CHEBI_77102 a rdfs:Class ;
rdfs:label "EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor" ;
rdfs:comment "An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using a quinone or related compound as acceptor (EC 1.3.5.*)." ;
rdfs:subClassOf obo:CHEBI_76729 .
obo:UBERON_0010056 a rdfs:Class ;
rdfs:label "future tongue" ;
rdfs:comment "A compound organ that has the potential to develop into a tongue." ;
rdfs:subClassOf obo:UBERON_0003103 , obo:UBERON_0005423 , obo:UBERON_0013765 .
obo:GO_0005775 a rdfs:Class ;
rdfs:label "vacuolar lumen" ;
rdfs:comment "The volume enclosed within the vacuolar membrane." ;
rdfs:subClassOf obo:GO_0031974 , obo:GO_0070013 .
obo:GO_0016331 a rdfs:Class ;
rdfs:label "morphogenesis of embryonic epithelium" ;
rdfs:comment "The process in which the anatomical structures of embryonic epithelia are generated and organized." ;
rdfs:subClassOf obo:GO_0002009 , obo:GO_0048598 .
obo:CHEBI_64641 a rdfs:Class ;
rdfs:label "divalent inorganic cation" ;
rdfs:comment "An inorganic cation with a valency of two." ;
rdfs:subClassOf obo:CHEBI_36915 .
obo:CHEBI_75616 a rdfs:Class ;
rdfs:label "gentamicin C(5+)" ;
rdfs:comment "An organic cation obtained by protonation of the five amino groups of any gentamicin C." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:UBERON_0005421 a rdfs:Class ;
rdfs:label "pectoral appendage apical ectodermal ridge" ;
rdfs:comment "An apical ectodermal ridge that is part of a pectoral appendage bud." ;
rdfs:subClassOf obo:UBERON_0004356 .
obo:CL_4072102 a rdfs:Class ;
rdfs:label "Purkinje layer interneuron" ;
rdfs:comment "A type of GABAergic interneuron residing in the Purkinje cell layer of the cerebellar cortex." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_4023057 .
obo:CHEBI_84186 a rdfs:Class ;
rdfs:label "L-proline derivative" ;
rdfs:comment "A proteinogenic amino acid derivative resulting from reaction of L-proline at the amino group or the carboxy group, or from the replacement of any hydrogen of L-proline by a heteroatom." ;
rdfs:subClassOf obo:CHEBI_26273 , obo:CHEBI_83811 .
obo:GO_0051051 a rdfs:Class ;
rdfs:label "negative regulation of transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0051049 , obo:GO_0065007 .
obo:PHIPO_0000869 a rdfs:Class ;
rdfs:label "sensitive to D-cycloserine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to D-cycloserine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1902652 a rdfs:Class ;
rdfs:label "secondary alcohol metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving secondary alcohol." ;
rdfs:subClassOf obo:GO_0006066 .
obo:GO_0014058 a rdfs:Class ;
rdfs:label "negative regulation of acetylcholine secretion, neurotransmission" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine." ;
rdfs:subClassOf obo:GO_0014056 , obo:GO_0032223 , obo:GO_0046929 , obo:GO_0051953 , obo:GO_0065007 .
obo:GO_0043589 a rdfs:Class ;
rdfs:label "skin morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0009887 .
obo:GO_0001508 a rdfs:Class ;
rdfs:label "action potential" ;
rdfs:comment "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities." ;
rdfs:subClassOf obo:GO_0042391 .
obo:GO_0090063 a rdfs:Class ;
rdfs:label "positive regulation of microtubule nucleation" ;
rdfs:comment "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." ;
rdfs:subClassOf obo:GO_0010968 , obo:GO_0031116 , obo:GO_0065007 .
obo:PHIPO_0000084 a rdfs:Class ;
rdfs:label "obsolete increased asexual spore motility" .
obo:GO_0002548 a rdfs:Class ;
rdfs:label "monocyte chemotaxis" ;
rdfs:comment "The movement of a monocyte in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0006935 , obo:GO_0030595 , obo:GO_0071674 , obo:GO_0097529 .
obo:GO_0032989 a rdfs:Class ;
rdfs:label "cellular anatomical entity morphogenesis" ;
rdfs:comment "The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system." ;
rdfs:subClassOf obo:GO_0016043 .
obo:GO_0001976 a rdfs:Class ;
rdfs:label "nervous system process involved in regulation of systemic arterial blood pressure" ;
rdfs:comment "The regulation of blood pressure mediated by detection of stimuli and a neurological response." ;
rdfs:subClassOf obo:GO_0050877 .
obo:UBERON_0034921 a rdfs:Class ;
rdfs:label "multi organ part structure" ;
rdfs:comment "An multicellular anatomical structure that has subparts of multiple organs as a part." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:GO_0007275 a rdfs:Class ;
rdfs:label "multicellular organism development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ;
rdfs:subClassOf obo:GO_0032501 , obo:GO_0048856 .
obo:GO_1900248 a rdfs:Class ;
rdfs:label "negative regulation of cytoplasmic translational elongation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation." ;
rdfs:subClassOf obo:GO_0045900 , obo:GO_0065007 , obo:GO_1900247 , obo:GO_2000766 .
obo:GO_1902867 a rdfs:Class ;
rdfs:label "negative regulation of retina development in camera-type eye" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1902866 .
obo:GO_0043065 a rdfs:Class ;
rdfs:label "positive regulation of apoptotic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." ;
rdfs:subClassOf obo:GO_0042981 , obo:GO_0043068 , obo:GO_0065007 .
obo:GO_0001558 a rdfs:Class ;
rdfs:label "regulation of cell growth" ;
rdfs:comment "Any process that modulates the frequency, rate, extent or direction of cell growth." ;
rdfs:subClassOf obo:GO_0040008 , obo:GO_0051128 , obo:GO_0065007 .
obo:PR_000016043 a rdfs:Class ;
rdfs:label "T-cell acute lymphocytic leukemia protein 1" ;
rdfs:comment "A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0022361 a rdfs:Class ;
rdfs:label "lung field" ;
rdfs:comment "A specific region of the foregut into the area in which the lung will develop." ;
rdfs:subClassOf obo:UBERON_0007688 .
obo:GO_0030031 a rdfs:Class ;
rdfs:label "cell projection assembly" ;
rdfs:comment "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0030030 .
obo:PHIPO_0000006 a rdfs:Class ;
rdfs:label "pathogenicity phenotype" ;
rdfs:comment "A phenotype that is relevant to pathogenicity. Pathogenicity is the ability of an organism, a pathogen, to produce an infectious disease in another organism" ;
rdfs:subClassOf obo:PHIPO_0001179 .
obo:CHEBI_16704 a rdfs:Class ;
rdfs:label "uridine" ;
rdfs:comment "A ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a β‒N1-glycosidic bond." ;
rdfs:subClassOf obo:CHEBI_27242 .
obo:CL_4310148 a rdfs:Class ;
rdfs:label "OB FRMD7 GABA GABAergic neuron (Primate)" ;
rdfs:comment "A GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB FRMD7 GABA." ;
rdfs:subClassOf obo:CL_0000617 .
obo:UBERON_0001892 a rdfs:Class ;
rdfs:label "rhombomere" ;
rdfs:comment "A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure.[WP]." ;
rdfs:subClassOf obo:UBERON_0004731 .
obo:CHEBI_33300 a rdfs:Class ;
rdfs:label "pnictogen" ;
rdfs:comment "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." ;
rdfs:subClassOf obo:CHEBI_33560 .
obo:UBERON_0002049 a rdfs:Class ;
rdfs:label "vasculature" ;
rdfs:comment "An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face." ;
rdfs:subClassOf obo:UBERON_0000477 .
obo:CL_4310111 a rdfs:Class ;
rdfs:label "SN-VTR GAD2 Dopa dopaminergic neuron (Primate)" ;
rdfs:comment "A dopaminergic neuron of the Primates brain. These cells are located in the striatum, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR GAD2 Dopa." ;
rdfs:subClassOf obo:CL_4042025 .
obo:GO_0034308 a rdfs:Class ;
rdfs:label "primary alcohol metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." ;
rdfs:subClassOf obo:GO_0006066 .
obo:GO_0044238 a rdfs:Class ;
rdfs:label "primary metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ;
rdfs:subClassOf obo:GO_0008152 .
obo:UBERON_0013160 a rdfs:Class ;
rdfs:label "epithalamus ventricular layer" ;
rdfs:subClassOf obo:UBERON_0004060 .
obo:GO_0003156 a rdfs:Class ;
rdfs:label "regulation of animal organ formation" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000027 .
obo:GO_0002731 a rdfs:Class ;
rdfs:label "negative regulation of dendritic cell cytokine production" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production." ;
rdfs:subClassOf obo:GO_0002704 , obo:GO_0002719 , obo:GO_0002730 , obo:GO_0065007 .
obo:PHIPO_0000998 a rdfs:Class ;
rdfs:label "pathogen morphology phenotype during colonization of host"@en ;
rdfs:comment "A pathogen host interaction phenotype which affects the pathogen morphology during host colonization. This relates to the pathogen colonization of the body, tissues, or cells of the host organism." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:CL_1000478 a rdfs:Class ;
rdfs:label "transitional myocyte of sinoatrial node" ;
rdfs:comment "A transitional myocyte that is part of the sinoatrial node." ;
rdfs:subClassOf obo:CL_0002073 , obo:CL_1000409 .
obo:UBERON_0016526 a rdfs:Class ;
rdfs:label "lobe of cerebral hemisphere" ;
rdfs:comment "Subdivision of telencephalon which is one of a number of subdivisions of each hemisphere separated by both real landmarks (sulci and fissures) and arbitrary boundaries[FMA,modified]." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:CL_0001059 a rdfs:Class ;
rdfs:label "common myeloid progenitor, CD34-positive" ;
rdfs:comment "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1." ;
rdfs:subClassOf obo:CL_0000049 , obo:CL_0011026 .
obo:CL_0000313 a rdfs:Class ;
rdfs:label "serous secreting cell" ;
rdfs:comment "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." ;
rdfs:subClassOf obo:CL_0000159 .
obo:CL_4307005 a rdfs:Class ;
rdfs:label "CB PLI GABA Ly6d Purkinje layer interneuron" ;
rdfs:comment "A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ly6d (Mmus), Kit (Mmus). It is distinguished from other CB PLI Gly-Gaba cells by expression of Ly6d. It is GABAergic (inferred from expression of Gad1, Gad2, Slc32a1). These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae, Interposed nucleus, Nodulus (X) . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5185 CB PLI Gly-Gaba_4." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300349 .
obo:GO_0060281 a rdfs:Class ;
rdfs:label "regulation of oocyte development" ;
rdfs:comment "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905879 .
obo:PHIPO_0001025 a rdfs:Class ;
rdfs:label "altered protein level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of protein measured in a cell differs from normal. Total protein or a specific protein may be affected." ;
rdfs:subClassOf obo:PHIPO_0000944 .
obo:GO_1904206 a rdfs:Class ;
rdfs:label "positive regulation of skeletal muscle hypertrophy" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy." ;
rdfs:subClassOf obo:GO_0014742 , obo:GO_0014744 , obo:GO_0065007 , obo:GO_1904204 .
obo:GO_0002068 a rdfs:Class ;
rdfs:label "glandular epithelial cell development" ;
rdfs:comment "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." ;
rdfs:subClassOf obo:GO_0002066 , obo:GO_0032502 .
obo:GO_0003149 a rdfs:Class ;
rdfs:label "membranous septum morphogenesis" ;
rdfs:comment "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0048143 a rdfs:Class ;
rdfs:label "astrocyte activation" ;
rdfs:comment "A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0061900 .
obo:PHIPO_0001071 a rdfs:Class ;
rdfs:label "obsolete viable host organism with pathogen" ;
rdfs:comment "A pathogen host interaction organism viability phenotype where a host organism is viable in the presence of a pathogen." .
obo:CL_0000573 a rdfs:Class ;
rdfs:label "retinal cone cell" ;
rdfs:comment "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." ;
rdfs:subClassOf obo:CL_0010009 .
obo:PHIPO_0001305 a rdfs:Class ;
rdfs:label "resistance to non-ionic osmotic stress"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to a non-ionic osmotic stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide." ;
rdfs:subClassOf obo:PHIPO_0001302 .
obo:PHIPO_0001030 a rdfs:Class ;
rdfs:label "altered cellular toxin level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of toxin measured in a cell differs from normal." ;
rdfs:subClassOf obo:PHIPO_0000944 .
obo:GO_0005172 a rdfs:Class ;
rdfs:label "vascular endothelial growth factor receptor binding" ;
rdfs:comment "Binding to a vascular endothelial growth factor receptor." ;
rdfs:subClassOf obo:GO_0005126 , obo:GO_0005488 , obo:GO_0070851 .
obo:GO_0005764 a rdfs:Class ;
rdfs:label "lysosome" ;
rdfs:comment "A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions." ;
rdfs:subClassOf obo:GO_0000323 .
obo:UBERON_0034729 a rdfs:Class ;
rdfs:label "sympathetic nerve" ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:GO_0060429 a rdfs:Class ;
rdfs:label "epithelium development" ;
rdfs:comment "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." ;
rdfs:subClassOf obo:GO_0009888 , obo:GO_0048856 .
obo:GO_0001503 a rdfs:Class ;
rdfs:label "ossification" ;
rdfs:comment "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance." ;
rdfs:subClassOf obo:GO_0032501 .
obo:GO_0045165 a rdfs:Class ;
rdfs:label "cell fate commitment" ;
rdfs:comment "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." ;
rdfs:subClassOf obo:GO_0048869 .
obo:CHEBI_83294 a rdfs:Class ;
rdfs:label "(S)-fenpropidin" ;
rdfs:comment "A 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine that has S configuration." ;
rdfs:subClassOf obo:CHEBI_83291 .
obo:GO_0050907 a rdfs:Class ;
rdfs:label "detection of chemical stimulus involved in sensory perception" ;
rdfs:comment "The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception." ;
rdfs:subClassOf obo:GO_0009593 , obo:GO_0050906 .
obo:GO_0055019 a rdfs:Class ;
rdfs:label "negative regulation of cardiac muscle fiber development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." ;
rdfs:subClassOf obo:GO_0010721 , obo:GO_0051154 , obo:GO_0055018 , obo:GO_0065007 .
obo:UBERON_0008115 a rdfs:Class ;
rdfs:label "surface of cartilage" ;
rdfs:comment "An anatomical surface that is part of a cartilage element." ;
rdfs:subClassOf obo:UBERON_0036215 .
obo:GO_0051100 a rdfs:Class ;
rdfs:label "negative regulation of binding" ;
rdfs:comment "Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf obo:GO_0044092 , obo:GO_0051098 , obo:GO_0065007 .
obo:GO_0051224 a rdfs:Class ;
rdfs:label "negative regulation of protein transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051051 , obo:GO_0051223 , obo:GO_0065007 , obo:GO_1904950 .
obo:GO_0006996 a rdfs:Class ;
rdfs:label "organelle organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0016043 .
obo:GO_0021592 a rdfs:Class ;
rdfs:label "fourth ventricle development" ;
rdfs:comment "The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0021523 a rdfs:Class ;
rdfs:label "somatic motor neuron differentiation" ;
rdfs:comment "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0021522 , obo:GO_0030154 .
obo:CHEBI_26588 a rdfs:Class ;
rdfs:label "1,3,5-triazines" ;
rdfs:comment "Any compound with a 1,3,5-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 3 and 5 of the core benzene ring structure." ;
rdfs:subClassOf obo:CHEBI_38102 .
obo:GO_0090071 a rdfs:Class ;
rdfs:label "negative regulation of ribosome biogenesis" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0065007 , obo:GO_0090069 .
obo:PHIPO_0000760 a rdfs:Class ;
rdfs:label "sensitive to gentamicin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to gentamicin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_9997 a rdfs:Class ;
rdfs:label "pristinamycin IIA" ;
rdfs:comment "A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus." ;
rdfs:subClassOf obo:CHEBI_140325 , obo:CHEBI_140326 , obo:CHEBI_23763 , obo:CHEBI_24995 , obo:CHEBI_25105 , obo:CHEBI_35681 , obo:CHEBI_3992 , obo:CHEBI_46812 , obo:CHEBI_51751 .
obo:PHIPO_0001424 a rdfs:Class ;
rdfs:label "sensitive to imazalil" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to imazalil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0021982 a rdfs:Class ;
rdfs:label "pineal gland development" ;
rdfs:comment "The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms." ;
rdfs:subClassOf obo:GO_0048732 , obo:GO_0048856 .
obo:GO_0022409 a rdfs:Class ;
rdfs:label "positive regulation of cell-cell adhesion" ;
rdfs:comment "Any process that activates or increases the rate or extent of cell adhesion to another cell." ;
rdfs:subClassOf obo:GO_0022407 , obo:GO_0045785 , obo:GO_0065007 .
obo:GO_0061900 a rdfs:Class ;
rdfs:label "glial cell activation" ;
rdfs:comment "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 .
obo:GO_0036194 a rdfs:Class ;
rdfs:label "muscle cell projection" ;
rdfs:comment "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." ;
rdfs:subClassOf obo:GO_0120025 .
obo:CL_1000467 a rdfs:Class ;
rdfs:label "chromaffin cell of left ovary" ;
rdfs:comment "A chromaffin cell that is part of the left ovary." ;
rdfs:subClassOf obo:CL_0000166 , obo:CL_1000465 .
obo:UBERON_0002082 a rdfs:Class ;
rdfs:label "cardiac ventricle" ;
rdfs:comment "Cardiac chamber through which blood leaves the heart." ;
rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0004151 .
obo:GO_0006942 a rdfs:Class ;
rdfs:label "regulation of striated muscle contraction" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of striated muscle contraction." ;
rdfs:subClassOf obo:GO_0006937 , obo:GO_0065007 .
obo:GO_0046530 a rdfs:Class ;
rdfs:label "photoreceptor cell differentiation" ;
rdfs:comment "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030182 .
obo:CL_4030051 a rdfs:Class ;
rdfs:label "nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron" ;
rdfs:comment "A DRD1-expressing medium spiny neuron that is part of a nucleus accumbens shell or olfactory tubercle." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_1001474 .
obo:GO_2000473 a rdfs:Class ;
rdfs:label "positive regulation of hematopoietic stem cell migration" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration." ;
rdfs:subClassOf obo:GO_0030335 , obo:GO_0065007 , obo:GO_2000471 .
obo:GO_0050770 a rdfs:Class ;
rdfs:label "regulation of axonogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron." ;
rdfs:subClassOf obo:GO_0010975 , obo:GO_0022603 , obo:GO_0065007 .
obo:UBERON_0011108 a rdfs:Class ;
rdfs:label "synovial joint of pectoral girdle" ;
rdfs:comment "A synovial joint that is part of a pectoral girdle region." ;
rdfs:subClassOf obo:UBERON_0002217 , obo:UBERON_0008114 .
obo:PHIPO_0000140 a rdfs:Class ;
rdfs:label "decreased duration of protein-protein interaction"@en ;
rdfs:comment "A single species molecular function phenotype in which the binding of one protein to another occurs for a shorter time than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000133 .
obo:GO_0072594 a rdfs:Class ;
rdfs:label "establishment of protein localization to organelle" ;
rdfs:comment "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." ;
rdfs:subClassOf obo:GO_0033365 , obo:GO_0045184 .
obo:GO_0031507 a rdfs:Class ;
rdfs:label "heterochromatin formation" ;
rdfs:comment "An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation." ;
rdfs:subClassOf obo:GO_0006325 , obo:GO_0022607 , obo:GO_0045814 , obo:GO_0070828 .
obo:UBERON_0001555 a rdfs:Class ;
rdfs:label "digestive tract" ;
rdfs:comment "A tube extending from the mouth to the anus." ;
rdfs:subClassOf obo:UBERON_0000025 .
obo:CHEBI_16134 a rdfs:Class ;
rdfs:label "ammonia" ;
rdfs:comment "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." ;
rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_35107 , obo:CHEBI_37176 .
obo:GO_0061048 a rdfs:Class ;
rdfs:label "negative regulation of branching involved in lung morphogenesis" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." ;
rdfs:subClassOf obo:GO_0051241 , obo:GO_0061046 , obo:GO_0065007 , obo:GO_1905331 .
obo:PHIPO_0000165 a rdfs:Class ;
rdfs:label "obsolete abnormal host lesion formation with pathogen" .
obo:GO_2000179 a rdfs:Class ;
rdfs:label "positive regulation of neural precursor cell proliferation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation." ;
rdfs:subClassOf obo:GO_0008284 , obo:GO_0065007 , obo:GO_2000177 .
obo:CL_0000622 a rdfs:Class ;
rdfs:label "acinar cell" ;
rdfs:comment "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus)." ;
rdfs:subClassOf obo:CL_0000150 , obo:CL_0000154 .
obo:UBERON_0003316 a rdfs:Class ;
rdfs:label "mesenchyme of yolk sac" ;
rdfs:comment "The portion of the yolk sac that is derived from mesoderm and consists of mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0010333 .
obo:GO_0010556 a rdfs:Class ;
rdfs:label "regulation of macromolecule biosynthetic process" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0060255 , obo:GO_0065007 .
obo:PHIPO_0000621 a rdfs:Class ;
rdfs:label "resistance to gatifloxacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to gatifloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0005594 a rdfs:Class ;
rdfs:label "head somite" ;
rdfs:comment "Somite located in the head region, caudal to the otic vesicle." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0002329 , obo:UBERON_0005291 .
obo:PHIPO_0001213 a rdfs:Class ;
rdfs:label "abolished hyphal growth"@en ;
rdfs:comment "An individual organism growth phenotype in which the growth of hyphae is abolished (it was present and is now absent)." ;
rdfs:subClassOf obo:PHIPO_0001212 .
obo:GO_0009893 a rdfs:Class ;
rdfs:label "positive regulation of metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0048522 , obo:GO_0065007 .
obo:CHEBI_600103 a rdfs:Class ;
rdfs:label "daptomycin" ;
rdfs:comment "A polypeptide comprising N-decanoyltryptophan, asparagine, aspartic acid, threonine, glycine, ornithine, aspartic acid, D-alanine, aspartic acid, glycine, D-serine, threo-3-methylglutamic acid and 3-anthraniloylalanine (also known as kynurinine) coupled in sequence and lactonised by condensation of the carboxylic acid group of the 3-anthraniloylalanine with the alcohol group of the threonine residue." ;
rdfs:subClassOf obo:CHEBI_24533 , obo:CHEBI_25061 , obo:CHEBI_25106 .
obo:UBERON_0011214 a rdfs:Class ;
rdfs:label "nucleus of midbrain tectum" ;
rdfs:comment "A neural nucleus that is part of a midbrain tectum." ;
rdfs:subClassOf obo:UBERON_0000125 , obo:UBERON_0009661 .
obo:UBERON_0004700 a rdfs:Class ;
rdfs:label "arterial system endothelium" ;
rdfs:comment "An endothelium that is part of an arterial system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0004852 .
obo:UBERON_0002037 a rdfs:Class ;
rdfs:label "cerebellum" ;
rdfs:comment "Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]." ;
rdfs:subClassOf obo:UBERON_0002616 .
obo:GO_0004553 a rdfs:Class ;
rdfs:label "hydrolase activity, hydrolyzing O-glycosyl compounds" ;
rdfs:comment "Catalysis of the hydrolysis of any O-glycosyl bond." ;
rdfs:subClassOf obo:GO_0016798 .
obo:PHIPO_0001383 a rdfs:Class ;
rdfs:label "sensitive to fenpiclonil" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenpiclonil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0005290 a rdfs:Class ;
rdfs:label "myelencephalon" ;
rdfs:comment "The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]." ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0004733 .
obo:PHIPO_0001249 a rdfs:Class ;
rdfs:label "chitin hydrolysis absent"@en ;
rdfs:comment "A single species metabolic cellular process phenotype, in which a pathogen effector prevents the hydrolysis of chitin by chitinases." ;
rdfs:subClassOf obo:PHIPO_0001147 .
obo:GO_0060759 a rdfs:Class ;
rdfs:label "regulation of response to cytokine stimulus" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 .
obo:CHEBI_24586 a rdfs:Class ;
rdfs:label "hexosamine" ;
rdfs:comment "Any 6-carbon amino monosaccharide with at least one alcoholic hydroxy group replaced by an amino group." ;
rdfs:subClassOf obo:CHEBI_60926 .
obo:GO_0006979 a rdfs:Class ;
rdfs:label "response to oxidative stress" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0006950 .
obo:CHEBI_35479 a rdfs:Class ;
rdfs:label "alkali metal salt" ;
rdfs:subClassOf obo:CHEBI_24866 , obo:CHEBI_33296 .
obo:UBERON_0004215 a rdfs:Class ;
rdfs:label "back nerve" ;
rdfs:comment "A nerve that is part of a back [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:CHEBI_27208 a rdfs:Class ;
rdfs:label "unsaturated fatty acid" ;
rdfs:comment "Any fatty acid containing at least one C=C or C≡C bond." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:CHEBI_59831 a rdfs:Class ;
rdfs:label "enyne" ;
rdfs:comment "An acetylenic and an olefinic compound containing a carbon chain that contains a carbon-carbon double bond and a carbon-carbon triple bond." ;
rdfs:subClassOf obo:CHEBI_73474 , obo:CHEBI_78840 .
obo:CHEBI_71321 a rdfs:Class ;
rdfs:label "fusidate" ;
rdfs:comment "A steroid acid anion that is the conjugate base of fusidic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_50160 .
obo:GO_0043009 a rdfs:Class ;
rdfs:label "chordate embryonic development" ;
rdfs:comment "The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching." ;
rdfs:subClassOf obo:GO_0009792 .
obo:GO_0061189 a rdfs:Class ;
rdfs:label "positive regulation of sclerotome development" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0061190 , obo:GO_0065007 .
obo:PHIPO_0000630 a rdfs:Class ;
rdfs:label "resistance to oligomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to oligomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0060786 a rdfs:Class ;
rdfs:label "regulation of cell differentiation involved in tissue homeostasis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue." ;
rdfs:subClassOf obo:GO_0045595 .
obo:CHEBI_83734 a rdfs:Class ;
rdfs:label "sterol demethylation inhibitor" ;
rdfs:comment "A sterol biosynthesis inhibitor that acts by inhibiting the C14 demethylation step within fungal steroid biosynthesis." ;
rdfs:subClassOf obo:CHEBI_35718 , obo:CHEBI_83317 .
obo:UBERON_0001779 a rdfs:Class ;
rdfs:label "iris stroma" ;
rdfs:comment "The delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae." ;
rdfs:subClassOf obo:UBERON_0003891 .
obo:GO_0014912 a rdfs:Class ;
rdfs:label "negative regulation of smooth muscle cell migration" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration." ;
rdfs:subClassOf obo:GO_0014910 , obo:GO_0030336 , obo:GO_0065007 .
obo:GO_0034764 a rdfs:Class ;
rdfs:label "positive regulation of transmembrane transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0034762 , obo:GO_0048522 , obo:GO_0051050 , obo:GO_0065007 .
obo:PHIPO_0000132 a rdfs:Class ;
rdfs:label "protein-protein interaction phenotype"@en ;
rdfs:comment "A single species phenotype that affects the binding of one protein to another. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000158 .
obo:PR_000001898 a rdfs:Class ;
rdfs:label "neprilysin" ;
rdfs:comment "A protein that is a translation product of the human MME gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:PHIPO_0000017 a rdfs:Class ;
rdfs:label "abnormal single species phenotype" ;
rdfs:comment "A single organism phenotype which is abnormal (i.e. different than wild-type)." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:CLM_1000074 a rdfs:Class ;
rdfs:label "NS forest marker set of lamp5 GABAergic interneuron (Human neocortex)." ;
rdfs:subClassOf obo:SO_0001260 .
obo:GO_0005587 a rdfs:Class ;
rdfs:label "collagen type IV trimer" ;
rdfs:comment "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes." ;
rdfs:subClassOf obo:GO_0098642 .
obo:GO_0071229 a rdfs:Class ;
rdfs:label "cellular response to acid chemical" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." ;
rdfs:subClassOf obo:GO_0001101 , obo:GO_0070887 .
obo:CHEBI_87012 a rdfs:Class ;
rdfs:label "amide antifungal agent" ;
rdfs:comment "A compound that has significant antifungal properties whose structure contains an amide moiety." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:GO_0051938 a rdfs:Class ;
rdfs:label "L-glutamate import" ;
rdfs:comment "The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0006835 , obo:GO_0015800 , obo:GO_0015807 .
obo:CHEBI_7451 a rdfs:Class ;
rdfs:label "naftifine" ;
rdfs:comment "A tertiary amine in which the nitrogen is substituted by methyl, α-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections." ;
rdfs:subClassOf obo:CHEBI_25477 , obo:CHEBI_32876 , obo:CHEBI_87127 .
obo:UBERON_0039857 a rdfs:Class ;
rdfs:label "left ovarian vein" ;
rdfs:comment "Ovarian vein, each instance of which is a tributary of some left renal vein that drains the left pampiniform plexus of some broad ligament." ;
rdfs:subClassOf obo:UBERON_0001145 .
obo:BFO_0000031 a rdfs:Class ;
rdfs:label "generically dependent continuant"@en ;
rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:UBERON_0001651 a rdfs:Class ;
rdfs:label "right pulmonary artery" ;
rdfs:comment "The pulmonary artery that supplies the right lung." ;
rdfs:subClassOf obo:UBERON_0001637 .
obo:PHIPO_0000497 a rdfs:Class ;
rdfs:label "normal toxin biosynthetic process"@en ;
rdfs:comment "A single organism phenotype in which the toxin biosynthetic process is normal (i.e. same as the wild type)." ;
rdfs:subClassOf obo:PHIPO_0000403 , obo:PHIPO_0000496 .
obo:GO_0032290 a rdfs:Class ;
rdfs:label "peripheral nervous system myelin formation" ;
rdfs:comment "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system." ;
rdfs:subClassOf obo:GO_0032288 .
obo:GO_0030264 a rdfs:Class ;
rdfs:label "nuclear fragmentation involved in apoptotic nuclear change" ;
rdfs:comment "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA." ;
rdfs:subClassOf obo:GO_0071763 .
obo:GO_0010712 a rdfs:Class ;
rdfs:label "regulation of collagen metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0065007 .
obo:PHIPO_0001130 a rdfs:Class ;
rdfs:label "stunted host growth during pathogen colonization"@en ;
rdfs:comment "A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in a decreased size of the host organism." ;
rdfs:subClassOf obo:PHIPO_0001006 .
obo:GO_2000287 a rdfs:Class ;
rdfs:label "positive regulation of myotome development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of myotome development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0065007 , obo:GO_2000290 .
obo:CL_0000136 a rdfs:Class ;
rdfs:label "adipocyte" ;
rdfs:comment "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." ;
rdfs:subClassOf obo:CL_0000325 , obo:CL_0002320 .
obo:CL_1000311 a rdfs:Class ;
rdfs:label "adipocyte of epicardial fat of left ventricle" ;
rdfs:comment "An adipocyte that is part of the epicardial fat of left ventricle." ;
rdfs:subClassOf obo:CL_1000309 .
obo:GO_0048103 a rdfs:Class ;
rdfs:label "somatic stem cell division" ;
rdfs:comment "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line." ;
rdfs:subClassOf obo:GO_0017145 , obo:GO_0051301 .
obo:GO_0010635 a rdfs:Class ;
rdfs:label "regulation of mitochondrial fusion" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment." ;
rdfs:subClassOf obo:GO_0010821 , obo:GO_0022603 , obo:GO_0065007 .
obo:GO_0042423 a rdfs:Class ;
rdfs:label "catecholamine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ;
rdfs:subClassOf obo:GO_0006584 , obo:GO_0009058 , obo:GO_0009713 , obo:GO_0042401 .
obo:UBERON_0001532 a rdfs:Class ;
rdfs:label "internal carotid artery" ;
rdfs:comment "A terminal branch of the left or right common carotid artery which supplies oxygenated blood to the brain and eyes[MP]." ;
rdfs:subClassOf obo:UBERON_0003496 , obo:UBERON_0005396 .
obo:UBERON_0018251 a rdfs:Class ;
rdfs:label "meningeal vein" ;
rdfs:comment "One of the veins draining a meninix." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:GO_0002213 a rdfs:Class ;
rdfs:label "defense response to insect" ;
rdfs:comment "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism." ;
rdfs:subClassOf obo:GO_0006952 , obo:GO_0051707 .
obo:CHEBI_50733 a rdfs:Class ;
rdfs:label "nutraceutical" ;
rdfs:comment "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:PHIPO_0001101 a rdfs:Class ;
rdfs:label "absence of pathogen asexual sporulation structures within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host where the pathogen asexual sporulation structures are absent." ;
rdfs:subClassOf obo:PHIPO_0000469 .
obo:GO_1905127 a rdfs:Class ;
rdfs:label "negative regulation of axo-dendritic protein transport" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0090317 , obo:GO_1905126 .
obo:GO_0009310 a rdfs:Class ;
rdfs:label "amine catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0009308 .
obo:GO_0044297 a rdfs:Class ;
rdfs:label "cell body" ;
rdfs:comment "The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0005938 a rdfs:Class ;
rdfs:label "cell cortex" ;
rdfs:comment "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." ;
rdfs:subClassOf obo:GO_0005737 .
obo:GO_0016887 a rdfs:Class ;
rdfs:label "ATP hydrolysis activity" ;
rdfs:comment "Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient." ;
rdfs:subClassOf obo:GO_0017111 .
obo:CHEBI_35570 a rdfs:Class ;
rdfs:label "mancude organic heterobicyclic parent" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_35571 .
obo:PHIPO_0000101 a rdfs:Class ;
rdfs:label "obsolete decreased motility" .
obo:GO_0045948 a rdfs:Class ;
rdfs:label "positive regulation of translational initiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translational initiation." ;
rdfs:subClassOf obo:GO_0006446 , obo:GO_0045727 , obo:GO_0065007 .
obo:CHEBI_22727 a rdfs:Class ;
rdfs:label "benzopyran" ;
rdfs:subClassOf obo:CHEBI_38104 , obo:CHEBI_38166 .
obo:CHEBI_28079 a rdfs:Class ;
rdfs:label "beta-L-arabinoside" ;
rdfs:subClassOf obo:CHEBI_22601 .
obo:CL_0002620 a rdfs:Class ;
rdfs:label "skin fibroblast" ;
rdfs:comment "A fibroblast of skin." ;
rdfs:subClassOf obo:CL_0000057 .
obo:CHEBI_38304 a rdfs:Class ;
rdfs:label "diazolidine" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 .
obo:UBERON_0019263 a rdfs:Class ;
rdfs:label "gray matter of hindbrain" ;
rdfs:subClassOf obo:UBERON_0002020 , obo:UBERON_0003528 .
obo:GO_0010758 a rdfs:Class ;
rdfs:label "regulation of macrophage chemotaxis" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0002688 , obo:GO_0065007 , obo:GO_1905521 .
obo:GO_1903179 a rdfs:Class ;
rdfs:label "regulation of dopamine biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dopamine biosynthetic process." ;
rdfs:subClassOf obo:GO_0009889 , obo:GO_0042053 , obo:GO_0065007 .
obo:CL_0002085 a rdfs:Class ;
rdfs:label "tanycyte" ;
rdfs:comment "A specialized elongated ventricular ependymal cell with one or more processes that extend into the brain parenchyma or associated blood vessels where they contact blood vessel endothelial cells and/or neurons. These cells are found in the ventricles and circumventricular organs of the brain. They are involved in hormonal regulation, gatekeeping molecules between the bloodstream and cerebrospinal fluid, metabolic sensing, and regulating food intake." ;
rdfs:subClassOf obo:CL_0000065 .
obo:GO_0098957 a rdfs:Class ;
rdfs:label "anterograde axonal transport of mitochondrion" ;
rdfs:comment "The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0008089 , obo:GO_0019896 .
obo:PHIPO_0001198 a rdfs:Class ;
rdfs:label "outcome of interaction phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype that affects the disease outcome of a pathogen host interaction." ;
rdfs:subClassOf obo:PHIPO_0000001 .
obo:CL_0000670 a rdfs:Class ;
rdfs:label "primordial germ cell" ;
rdfs:comment "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." ;
rdfs:subClassOf obo:CL_0000039 , obo:CL_0000219 .
obo:GO_0023026 a rdfs:Class ;
rdfs:label "MHC class II protein complex binding" ;
rdfs:comment "Binding to a class II major histocompatibility complex." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0023023 .
obo:GO_0005774 a rdfs:Class ;
rdfs:label "vacuolar membrane" ;
rdfs:comment "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0098588 .
obo:CHEBI_9321 a rdfs:Class ;
rdfs:label "sulbactam" ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_25865 .
obo:PHIPO_0000777 a rdfs:Class ;
rdfs:label "sensitive to oxytetracycline"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to oxytetracycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0042461 a rdfs:Class ;
rdfs:label "photoreceptor cell development" ;
rdfs:comment "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048666 .
obo:GO_0060020 a rdfs:Class ;
rdfs:label "Bergmann glial cell differentiation" ;
rdfs:comment "The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0048708 .
obo:UBERON_0014452 a rdfs:Class ;
rdfs:label "gustatory epithelium of tongue" ;
rdfs:comment "A gustatory epithelium that is part of a tongue." ;
rdfs:subClassOf obo:UBERON_0002926 , obo:UBERON_0003357 .
obo:CHEBI_86420 a rdfs:Class ;
rdfs:label "imidazole antifungal agent" ;
rdfs:comment "A compound that has significant antifungal properties whose structure contains an imidazole moiety." ;
rdfs:subClassOf obo:CHEBI_24780 .
obo:UBERON_0004276 a rdfs:Class ;
rdfs:label "fourth ventricle choroid plexus epithelium" ;
rdfs:comment "A choroid plexus epithelium that is part of a fourth ventricle [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003911 .
obo:UBERON_0007124 a rdfs:Class ;
rdfs:label "pharyngeal pouch 3" ;
rdfs:comment "A pharyngeal pouch that between pharyngeal arches 3 and 4." ;
rdfs:subClassOf obo:UBERON_0004117 .
a rdfs:Class ;
rdfs:label "Midbrain" ;
rdfs:subClassOf , obo:UBERON_0001891 .
obo:UBERON_0000091 a rdfs:Class ;
rdfs:label "bilaminar disc" ;
rdfs:comment "A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:PHIPO_0000220 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction metabolic process phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that affects the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." .
obo:UBERON_0009889 a rdfs:Class ;
rdfs:label "secondary heart field" ;
rdfs:comment "A specific region of the lateral mesoderm that will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract)." ;
rdfs:subClassOf obo:UBERON_0002050 , obo:UBERON_0005291 , obo:UBERON_0007688 .
obo:GO_0030029 a rdfs:Class ;
rdfs:label "actin filament-based process" ;
rdfs:comment "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0021563 a rdfs:Class ;
rdfs:label "glossopharyngeal nerve development" ;
rdfs:comment "Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." ;
rdfs:subClassOf obo:GO_0021545 , obo:GO_0048856 .
obo:UBERON_0007245 a rdfs:Class ;
rdfs:label "nuclear complex of neuraxis" ;
rdfs:comment "Gray matter of the central nervous system which is a collection of clustered nuclei." ;
rdfs:subClassOf obo:UBERON_0002020 .
obo:CHEBI_600520 a rdfs:Class ;
rdfs:label "micafungin" ;
rdfs:comment "A cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-β-D-glucan, an integral component of the fungal cell wall. It is used as the sodium salt for the treatment of invasive candidiasis, and of aspergillosis in patients who are intolerant of other therapy." ;
rdfs:subClassOf obo:CHEBI_57248 , obo:CHEBI_87113 .
obo:IDO_0000450 a rdfs:Class ;
rdfs:label "pathogenic disposition"@en ;
rdfs:comment "A disposition to initiate processes that result in a disorder."@en ;
rdfs:subClassOf obo:BFO_0000016 .
obo:RO_0000052 a rdf:Property ;
rdfs:label "inheres in"@en ;
rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0002314 .
obo:GO_0009665 a rdfs:Class ;
rdfs:label "plastid inheritance" ;
rdfs:comment "The partitioning of plastids between daughter cells at cell division." ;
rdfs:subClassOf obo:GO_0009657 , obo:GO_0048308 .
obo:CHEBI_39157 a rdfs:Class ;
rdfs:label "trichostatic acid" ;
rdfs:subClassOf obo:CHEBI_35983 , obo:CHEBI_79020 .
obo:PHIPO_0000737 a rdfs:Class ;
rdfs:label "sensitive to cyclosporine A"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to cyclosporine A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1903077 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to plasma membrane" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903076 , obo:GO_1904376 , obo:GO_1905476 .
obo:GO_0070233 a rdfs:Class ;
rdfs:label "negative regulation of T cell apoptotic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070229 , obo:GO_0070232 .
obo:UBERON_0000108 a rdfs:Class ;
rdfs:label "blastula stage" ;
rdfs:comment "An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:PHIPO_0000603 a rdfs:Class ;
rdfs:label "resistance to doxycycline"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to doxycycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1903054 a rdfs:Class ;
rdfs:label "negative regulation of extracellular matrix organization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1903053 .
obo:GO_0008502 a rdfs:Class ;
rdfs:label "melatonin receptor activity" ;
rdfs:comment "Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin." ;
rdfs:subClassOf obo:GO_0004930 , obo:GO_0038023 .
obo:PATO_0002062 a rdfs:Class ;
rdfs:label "physical quality of a process" ;
rdfs:subClassOf obo:PATO_0001236 .
obo:PHIPO_0001275 a rdfs:Class ;
rdfs:label "presence of viable pathogen sexual spores within host"@en ;
rdfs:comment "A pathogen reproductive phenotype within host in which the viability of sexual spores is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001271 .
obo:PHIPO_0001216 a rdfs:Class ;
rdfs:label "nutrient phenotype"@en ;
rdfs:comment "A growth phenotype which describes the change or absence of change of individuals or populations (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:GO_0010658 a rdfs:Class ;
rdfs:label "striated muscle cell apoptotic process" ;
rdfs:comment "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations." ;
rdfs:subClassOf obo:GO_0006915 , obo:GO_0010657 .
obo:GO_0007343 a rdfs:Class ;
rdfs:label "egg activation" ;
rdfs:comment "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm." ;
rdfs:subClassOf obo:GO_0001775 .
obo:PHIPO_0001047 a rdfs:Class ;
rdfs:label "pathogen toxin within host absent"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the pathogen produced toxin usually present during infection is absent or at a level too low to detect." ;
rdfs:subClassOf obo:PHIPO_0001045 .
obo:PR_000064867 a rdfs:Class ;
rdfs:label "protein-containing molecular entity" ;
rdfs:comment "A molecular entity that minimally consists of a protein." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:GO_0061037 a rdfs:Class ;
rdfs:label "negative regulation of cartilage development" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0061035 , obo:GO_0065007 .
obo:CHEBI_69136 a rdfs:Class ;
rdfs:label "latrunculin A" ;
rdfs:comment "A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes." ;
rdfs:subClassOf obo:CHEBI_25106 , obo:CHEBI_46733 , obo:CHEBI_48891 , obo:CHEBI_59780 .
obo:GO_2000835 a rdfs:Class ;
rdfs:label "negative regulation of androgen secretion" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_2000832 , obo:GO_2000834 .
obo:GO_0022402 a rdfs:Class ;
rdfs:label "cell cycle process" ;
rdfs:comment "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." ;
rdfs:subClassOf obo:GO_0009987 .
obo:GO_0051890 a rdfs:Class ;
rdfs:label "regulation of cardioblast differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1905207 , obo:GO_2000736 .
obo:UBERON_0009576 a rdfs:Class ;
rdfs:label "medulla oblongata sulcus limitans" ;
rdfs:comment "A sulcus limitans of neural tube that is part of a future medulla oblongata." ;
rdfs:subClassOf obo:UBERON_0005478 .
obo:CHEBI_33366 a rdfs:Class ;
rdfs:label "copper group element atom" ;
rdfs:subClassOf obo:CHEBI_33561 .
a rdfs:Class ;
rdfs:comment "An unconstrained type or object" .
obo:CHEBI_13941 a rdfs:Class ;
rdfs:label "carbamate" ;
rdfs:subClassOf obo:CHEBI_37022 .
obo:GO_1905503 a rdfs:Class ;
rdfs:label "regulation of motile cilium assembly" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of motile cilium assembly." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902017 .
obo:GO_0060440 a rdfs:Class ;
rdfs:label "trachea formation" ;
rdfs:comment "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches." ;
rdfs:subClassOf obo:GO_0048645 , obo:GO_0048646 .
obo:GO_0007416 a rdfs:Class ;
rdfs:label "synapse assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0034329 , obo:GO_0050808 .
obo:GO_1901192 a rdfs:Class ;
rdfs:label "positive regulation of formation of translation initiation ternary complex" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex." ;
rdfs:subClassOf obo:GO_0031334 , obo:GO_0065007 , obo:GO_1901190 .
obo:GO_1904950 a rdfs:Class ;
rdfs:label "negative regulation of establishment of protein localization" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_0070201 , obo:GO_1903828 .
obo:CL_0000255 a rdfs:Class ;
rdfs:label "eukaryotic cell" ;
rdfs:comment "Any cell that in taxon some Eukaryota." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0032974 a rdfs:Class ;
rdfs:label "amino acid transmembrane export from vacuole" ;
rdfs:comment "The directed movement of amino acids out of the vacuole, across the vacuolar membrane." ;
rdfs:subClassOf obo:GO_0003333 , obo:GO_0010496 , obo:GO_0034486 , obo:GO_0055085 .
obo:GO_0032938 a rdfs:Class ;
rdfs:label "negative regulation of translation in response to oxidative stress" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ;
rdfs:subClassOf obo:GO_0032057 , obo:GO_0043556 , obo:GO_0043558 , obo:GO_0065007 .
obo:PATO_0000462 a rdfs:Class ;
rdfs:label "absent" ;
rdfs:comment "A quality denoting the lack of an entity." ;
rdfs:subClassOf obo:PATO_0000070 .
obo:GO_0060096 a rdfs:Class ;
rdfs:label "serotonin secretion, neurotransmission" ;
rdfs:comment "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0001820 , obo:GO_0007269 .
obo:PHIPO_0001166 a rdfs:Class ;
rdfs:label "absence of host seed development induced by pathogen"@en ;
rdfs:comment "A host reproductive phenotype with pathogen where the process of host seed development is absent (GO:0048316)." ;
rdfs:subClassOf obo:PHIPO_0001165 .
obo:GO_0071971 a rdfs:Class ;
rdfs:label "extracellular exosome assembly" ;
rdfs:comment "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm." ;
rdfs:subClassOf obo:GO_0016050 , obo:GO_0022607 , obo:GO_0070925 .
obo:CHEBI_77981 a rdfs:Class ;
rdfs:label "vancomycin aglycone(1-)" ;
rdfs:comment "A peptide anion that is the conjugate base of vancomycin aglycone and the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." ;
rdfs:subClassOf obo:CHEBI_50525 , obo:CHEBI_60334 .
obo:PHIPO_0000820 a rdfs:Class ;
rdfs:label "sensitive to abamectin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to abamectin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0021614 a rdfs:Class ;
rdfs:label "glossopharyngeal nerve maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." ;
rdfs:subClassOf obo:GO_0021605 , obo:GO_0021700 .
obo:PHIPO_0000628 a rdfs:Class ;
rdfs:label "resistance to resveratrol"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to resveratrol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_47956 a rdfs:Class ;
rdfs:label "thiocarboxamide" ;
rdfs:comment "Any primary amide having its amide oxygen replaced by sulfur." ;
rdfs:subClassOf obo:CHEBI_33256 .
obo:GO_0080135 a rdfs:Class ;
rdfs:label "regulation of cellular response to stress" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 , obo:GO_0080134 .
obo:UBERON_0004864 a rdfs:Class ;
rdfs:label "vasculature of retina" ;
rdfs:comment "A vasculature that is part of a retina [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002049 , obo:UBERON_0002203 , obo:UBERON_0036302 .
obo:GO_0098876 a rdfs:Class ;
rdfs:label "vesicle-mediated transport to the plasma membrane" ;
rdfs:comment "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0016192 , obo:GO_0051668 .
obo:CHEBI_83709 a rdfs:Class ;
rdfs:label "(S)-flutriafol" ;
rdfs:subClassOf obo:CHEBI_83707 .
obo:PR_P37237 a rdfs:Class ;
rdfs:label "fibroblast growth factor 8 (mouse)" ;
rdfs:comment "A fibroblast growth factor 8 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000007499 , obo:PR_000029032 .
obo:GO_0021852 a rdfs:Class ;
rdfs:label "pyramidal neuron migration to cerebral cortex" ;
rdfs:comment "The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0021801 , obo:GO_0140650 .
obo:GO_0003209 a rdfs:Class ;
rdfs:label "cardiac atrium morphogenesis" ;
rdfs:comment "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." ;
rdfs:subClassOf obo:GO_0003206 , obo:GO_0009653 .
obo:CL_1000490 a rdfs:Class ;
rdfs:label "mesothelial cell of peritoneum" ;
rdfs:comment "A mesothelial cell that is part of the peritoneum." ;
rdfs:subClassOf obo:CL_0000077 .
obo:PHIPO_0000374 a rdfs:Class ;
rdfs:label "increased size of pathogen penetration structure when near host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the size of pathogen penetration stuctures near the host are increased." ;
rdfs:subClassOf obo:PHIPO_0000369 .
obo:UBERON_0002291 a rdfs:Class ;
rdfs:label "central canal of spinal cord" ;
rdfs:comment "Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord." ;
rdfs:subClassOf obo:UBERON_0004111 , obo:UBERON_0004121 .
obo:PHIPO_0000612 a rdfs:Class ;
rdfs:label "resistance to tunicamycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tunicamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_350546 a rdfs:Class .
obo:GO_0000045 a rdfs:Class ;
rdfs:label "autophagosome assembly" ;
rdfs:comment "The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm." ;
rdfs:subClassOf obo:GO_0070925 , obo:GO_1905037 .
obo:CHEBI_38298 a rdfs:Class ;
rdfs:label "benzodioxoles" ;
rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38104 .
obo:CL_0000108 a rdfs:Class ;
rdfs:label "cholinergic neuron" ;
rdfs:comment "A neuron that uses acetylcholine as a vesicular neurotransmitter." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000540 .
obo:CL_0000029 a rdfs:Class ;
rdfs:label "neural crest derived neuron" ;
rdfs:comment "Any neuron that develops from some migratory neural crest cell." ;
rdfs:subClassOf obo:CL_0000540 .
obo:PHIPO_0001327 a rdfs:Class ;
rdfs:label "normal growth on iprodione"@en ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to iprodione (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0003148 a rdfs:Class ;
rdfs:label "outflow tract septum morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060411 .
obo:UBERON_2001457 a rdfs:Class ;
rdfs:label "postcranial axial cartilage" ;
rdfs:comment "Cartilage which is part of the axial skeleton." ;
rdfs:subClassOf obo:UBERON_0007844 .
obo:GO_0008299 a rdfs:Class ;
rdfs:label "isoprenoid biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." ;
rdfs:subClassOf obo:GO_0006720 , obo:GO_0008610 .
obo:GO_0140238 a rdfs:Class ;
rdfs:label "presynaptic endocytosis" ;
rdfs:comment "A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." ;
rdfs:subClassOf obo:GO_0006897 , obo:GO_0051649 , obo:GO_0099003 .
obo:CL_0000995 a rdfs:Class ;
rdfs:label "CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor" ;
rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1100000)(PMID:19243617)." ;
rdfs:subClassOf obo:CL_0001060 , obo:CL_0011026 .
obo:GO_0045763 a rdfs:Class ;
rdfs:label "negative regulation of amino acid metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." ;
rdfs:subClassOf obo:GO_0006521 , obo:GO_0009892 , obo:GO_0065007 .
obo:GO_1905232 a rdfs:Class ;
rdfs:label "cellular response to L-glutamate" ;
rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus." ;
rdfs:subClassOf obo:GO_0070887 , obo:GO_0071230 , obo:GO_1901699 , obo:GO_1901701 , obo:GO_1902065 .
obo:GO_0016070 a rdfs:Class ;
rdfs:label "RNA metabolic process" ;
rdfs:comment "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0090304 .
obo:PHIPO_0000162 a rdfs:Class ;
rdfs:label "unicellular population growth phenotype"@en ;
rdfs:comment "A single species population growth phenotype that affects the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction)." ;
rdfs:subClassOf obo:PHIPO_0000509 .
obo:GO_0031268 a rdfs:Class ;
rdfs:label "pseudopodium organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0120036 .
obo:UBERON_0006240 a rdfs:Class ;
rdfs:label "future forebrain" ;
rdfs:comment "A presumptive structure that has the potential to develop into a forebrain." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:PHIPO_0001152 a rdfs:Class ;
rdfs:label "increased host membrane blebbing during pathogen invasion"@en ;
rdfs:comment "A pathogen host interaction phenotype where the morphology of the host plasma membrane has increased blebbing during pathogen invasion." ;
rdfs:subClassOf obo:PHIPO_0001006 .
obo:GO_0002252 a rdfs:Class ;
rdfs:label "immune effector process" ;
rdfs:comment "Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation." ;
rdfs:subClassOf obo:GO_0002376 .
obo:GO_0050868 a rdfs:Class ;
rdfs:label "negative regulation of T cell activation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation." ;
rdfs:subClassOf obo:GO_0050863 , obo:GO_0051250 , obo:GO_0065007 , obo:GO_1903038 .
obo:GO_1904680 a rdfs:Class ;
rdfs:label "peptide transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of a peptide from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0005215 , obo:GO_0022857 .
obo:CHEBI_35881 a rdfs:Class ;
rdfs:label "pnictogen hydride" ;
rdfs:subClassOf obo:CHEBI_33242 , obo:CHEBI_33302 .
obo:CHEBI_32863 a rdfs:Class ;
rdfs:label "secondary amine" ;
rdfs:comment "A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups." ;
rdfs:subClassOf obo:CHEBI_32952 , obo:CHEBI_50995 .
obo:UBERON_0003117 a rdfs:Class ;
rdfs:label "pharyngeal arch 6" ;
rdfs:comment "The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles." ;
rdfs:subClassOf obo:UBERON_0002539 .
obo:GO_0030036 a rdfs:Class ;
rdfs:label "actin cytoskeleton organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ;
rdfs:subClassOf obo:GO_0007010 , obo:GO_0016043 , obo:GO_0030029 .
obo:UBERON_0005092 a rdfs:Class ;
rdfs:label "right horn of sinus venosus" ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0005576 a rdfs:Class ;
rdfs:label "extracellular region" ;
rdfs:comment "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_75772 a rdfs:Class ;
rdfs:label "Saccharomyces cerevisiae metabolite" ;
rdfs:comment "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae )." ;
rdfs:subClassOf obo:CHEBI_76946 .
obo:CHEBI_33232 a rdfs:Class ;
rdfs:label "application" ;
rdfs:comment "Intended use of the molecular entity or part thereof by humans." ;
rdfs:subClassOf obo:CHEBI_50906 .
obo:PHIPO_0001446 a rdfs:Class ;
rdfs:label "reduced hyphal branching"@en ;
rdfs:comment "A single species cell morphology phenotype in which fungal hyphae form a decreased number of branches." ;
rdfs:subClassOf obo:PHIPO_0001427 .
obo:CHEBI_38180 a rdfs:Class ;
rdfs:label "polycyclic heteroarene" ;
rdfs:subClassOf obo:CHEBI_33833 .
obo:CL_4307088 a rdfs:Class ;
rdfs:label "OPC NN_1 Mms22l oligodendrocyte precursor cell (Mmus)" ;
rdfs:comment "A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Mms22l (Mmus), Top2a (Mmus). It is distinguished from other OPC NN_1 cells by expression of Mms22l, Foxg1, Top2a. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5268 OPC NN_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4300366 .
obo:UBERON_0034724 a rdfs:Class ;
rdfs:label "esophageal taste bud" ;
rdfs:comment "A taste bud that is located in the esophagus." ;
rdfs:subClassOf obo:UBERON_0001727 , obo:UBERON_0013765 .
obo:UBERON_0014637 a rdfs:Class ;
rdfs:label "thoracic spinal cord white matter" ;
rdfs:comment "A white matter of spinal cord that is part of a thoracic spinal cord." ;
rdfs:subClassOf obo:UBERON_0002318 .
obo:GO_0048313 a rdfs:Class ;
rdfs:label "Golgi inheritance" ;
rdfs:comment "The partitioning of Golgi apparatus between daughter cells at cell division." ;
rdfs:subClassOf obo:GO_0007030 , obo:GO_0048308 .
obo:GO_0150079 a rdfs:Class ;
rdfs:label "negative regulation of neuroinflammatory response" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response." ;
rdfs:subClassOf obo:GO_0050728 , obo:GO_0065007 , obo:GO_0150077 .
obo:CHEBI_33832 a rdfs:Class ;
rdfs:label "organic cyclic compound" ;
rdfs:comment "Any organic molecule that consists of atoms connected in the form of a ring." ;
rdfs:subClassOf obo:CHEBI_33595 , obo:CHEBI_72695 .
obo:GO_0048370 a rdfs:Class ;
rdfs:label "lateral mesoderm formation" ;
rdfs:comment "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ;
rdfs:subClassOf obo:GO_0001707 , obo:GO_0048646 .
obo:PATO_0001397 a rdfs:Class ;
rdfs:label "cellular potency" ;
rdfs:comment "A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types." ;
rdfs:subClassOf obo:PATO_0001396 .
obo:CHEBI_29036 a rdfs:Class ;
rdfs:label "copper(2+)" ;
rdfs:comment "An ion of copper carrying a double positive charge." ;
rdfs:subClassOf obo:CHEBI_23378 , obo:CHEBI_30412 , obo:CHEBI_60240 .
obo:GO_1903569 a rdfs:Class ;
rdfs:label "positive regulation of protein localization to ciliary membrane" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1903566 , obo:GO_1903567 , obo:GO_1904377 , obo:GO_1905477 .
obo:GO_0005640 a rdfs:Class ;
rdfs:label "nuclear outer membrane" ;
rdfs:comment "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031965 , obo:GO_0031968 .
obo:GO_0002408 a rdfs:Class ;
rdfs:label "myeloid dendritic cell chemotaxis" ;
rdfs:comment "The movement of a myeloid dendritic cell in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0002407 , obo:GO_0006935 , obo:GO_0097529 .
obo:CHEBI_31577 a rdfs:Class ;
rdfs:label "ethylenediamine derivative" ;
rdfs:comment "Any organic amino compound that is a derivative of ethylenediamine." ;
rdfs:subClassOf obo:CHEBI_50047 .
obo:GO_0099524 a rdfs:Class ;
rdfs:label "postsynaptic cytosol" ;
rdfs:comment "The region of the cytosol consisting of all cytosol that is part of the postsynapse." ;
rdfs:subClassOf obo:GO_0005829 .
obo:GO_0061181 a rdfs:Class ;
rdfs:label "regulation of chondrocyte development" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." ;
rdfs:subClassOf obo:GO_0032330 , obo:GO_0060284 , obo:GO_0065007 .
obo:UBERON_0007267 a rdfs:Class ;
rdfs:label "trachea pre-cartilage rings" ;
rdfs:comment "A pre-cartilage condensation that is part of a trachea." ;
rdfs:subClassOf obo:UBERON_0005866 , obo:UBERON_0009505 .
obo:PHIPO_0000643 a rdfs:Class ;
rdfs:label "resistance to imipenem"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to imipenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000693 .
obo:PATO_0000402 a rdfs:Class ;
rdfs:label "branched" ;
rdfs:comment "A branchiness quality inhering in a bearer by virtue of the bearer's having branches." ;
rdfs:subClassOf obo:PATO_0002009 .
obo:PHIPO_0000014 a rdfs:Class ;
rdfs:label "increased virulence" ;
rdfs:comment "A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is increased (i.e. more symptoms than normal)." ;
rdfs:subClassOf obo:PHIPO_0000011 .
obo:PHIPO_0000338 a rdfs:Class ;
rdfs:label "increased pathogen cell to cell migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is increased compared to normal." ;
rdfs:subClassOf obo:PHIPO_0000334 .
obo:GO_0002702 a rdfs:Class ;
rdfs:label "positive regulation of production of molecular mediator of immune response" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response." ;
rdfs:subClassOf obo:GO_0002699 , obo:GO_0002700 , obo:GO_0010628 , obo:GO_0065007 .
obo:UBERON_0006535 a rdfs:Class ;
rdfs:label "skin secretion" ;
rdfs:comment "A portion of organism substance that secreted_by a zone of skin." ;
rdfs:subClassOf obo:UBERON_0000463 .
obo:GO_0048251 a rdfs:Class ;
rdfs:label "elastic fiber assembly" ;
rdfs:comment "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0085029 , obo:GO_0097435 .
obo:CHEBI_18282 a rdfs:Class ;
rdfs:label "nucleobase" ;
rdfs:comment "That part of DNA or RNA that may be involved in pairing." ;
rdfs:subClassOf obo:CHEBI_38101 .
a rdfs:Class ;
rdfs:label "Globus pallidus, external segment" ;
rdfs:subClassOf , obo:UBERON_0002476 .
obo:PHIPO_0000219 a rdfs:Class ;
rdfs:label "decreased level of pathogen deoxynivalenol within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen produced deoxynivalenol usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001045 .
obo:GO_0055123 a rdfs:Class ;
rdfs:label "digestive system development" ;
rdfs:comment "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:PHIPO_0000372 a rdfs:Class ;
rdfs:label "decreased size of pathogen penetration structure when near host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the size of pathogen penetration stuctures near the host are decreased." ;
rdfs:subClassOf obo:PHIPO_0000369 .
obo:UBERON_0013232 a rdfs:Class ;
rdfs:label "serous acinus" ;
rdfs:comment "The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells." ;
rdfs:subClassOf obo:UBERON_0009842 , obo:UBERON_0011858 .
obo:GO_0040014 a rdfs:Class ;
rdfs:label "regulation of multicellular organism growth" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." ;
rdfs:subClassOf obo:GO_0048638 , obo:GO_0051239 , obo:GO_0065007 .
obo:PHIPO_0001227 a rdfs:Class ;
rdfs:label "increased level of host defense-induced reducing sugar in apoplast"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host produced reducing sugars usually present in the apoplast during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:GO_0061458 a rdfs:Class ;
rdfs:label "reproductive system development" ;
rdfs:comment "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:GO_0042416 a rdfs:Class ;
rdfs:label "dopamine biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0042417 , obo:GO_0042423 .
obo:GO_0046832 a rdfs:Class ;
rdfs:label "negative regulation of RNA export from nucleus" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm." ;
rdfs:subClassOf obo:GO_0032240 , obo:GO_0046823 , obo:GO_0046831 , obo:GO_0065007 .
obo:PHIPO_0000860 a rdfs:Class ;
rdfs:label "sensitive to ertapenem"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ertapenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000819 .
obo:PHIPO_0000073 a rdfs:Class ;
rdfs:label "abnormal number of sexual spores"@en ;
rdfs:comment "A population phenotype in which the frequency of occurrence of sexual spores is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000077 .
obo:UBERON_0000001 a rdfs:Class ;
rdfs:label "gross anatomical part" ;
rdfs:comment "Anatomical structure that is part of a multicellular organism and is at the gross anatomical level, e.g. above the level of a cell. Included are portions of organism substances such as blood, multi-cell-part structures such as axon tracts, acellular anatomical structures such as hair, and organism subdivisions such as head. Excluded is the whole organism and more granular parts of the organism, such as atoms, molecules, macromolecular complexes and cells." ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:CHEBI_43176 a rdfs:Class ;
rdfs:label "hydroxy group" ;
rdfs:subClassOf obo:CHEBI_33246 .
obo:PHIPO_0001060 a rdfs:Class ;
rdfs:label "altered RNA level"@en ;
rdfs:comment "A single species cell phenotype in which the amount of RNA measured in a cell differs from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." ;
rdfs:subClassOf obo:PHIPO_0000944 .
obo:CHEBI_86478 a rdfs:Class ;
rdfs:label "antibiotic antifungal agent" ;
rdfs:comment "Heteroorganic entities that are microbial metabolites (or compounds derived from them) which have significant antifungal properties." ;
rdfs:subClassOf obo:CHEBI_33285 .
obo:GO_0003006 a rdfs:Class ;
rdfs:label "developmental process involved in reproduction" ;
rdfs:comment "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring." ;
rdfs:subClassOf obo:GO_0022414 , obo:GO_0032502 .
obo:UBERON_0003603 a rdfs:Class ;
rdfs:label "lower respiratory tract cartilage" ;
rdfs:comment "A cartilage that is part of a lower respiratory tract [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0003406 , obo:UBERON_0007844 .
obo:CHEBI_50297 a rdfs:Class ;
rdfs:label "canonical nucleotide residue" ;
rdfs:subClassOf obo:CHEBI_50319 .
obo:GO_0003315 a rdfs:Class ;
rdfs:label "heart rudiment formation" ;
rdfs:comment "The developmental process pertaining to the initial formation of the heart rudiment." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0045930 a rdfs:Class ;
rdfs:label "negative regulation of mitotic cell cycle" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." ;
rdfs:subClassOf obo:GO_0007346 , obo:GO_0045786 , obo:GO_0065007 .
obo:PR_Q9QXH4 a rdfs:Class ;
rdfs:label "integrin alpha-X (mouse)" ;
rdfs:comment "An integrin alpha-X that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001013 , obo:PR_000029032 .
obo:PHIPO_0000755 a rdfs:Class ;
rdfs:label "sensitive to amikacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to amikacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1990009 a rdfs:Class ;
rdfs:label "retinal cell apoptotic process" ;
rdfs:comment "Any apoptotic process in a retinal cell." ;
rdfs:subClassOf obo:GO_0006915 .
obo:CHEBI_26666 a rdfs:Class ;
rdfs:label "short-chain fatty acid" ;
rdfs:comment "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." ;
rdfs:subClassOf obo:CHEBI_35366 .
obo:PHIPO_0000260 a rdfs:Class ;
rdfs:label "obsolete normal pathogen host interaction protein transport" ;
rdfs:comment "A pathogen host interaction (cellular process??) phenotype in which protein transport is normal (i.e. indistinguishable from wild type)." .
obo:CHEBI_35489 a rdfs:Class ;
rdfs:label "organic disulfide" ;
rdfs:comment "Compounds of structure RSSR in which R and R' are organic groups." ;
rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_48343 .
obo:NCBITaxon_6960 a rdfs:Class ;
rdfs:label "Hexapoda" ;
rdfs:subClassOf obo:NCBITaxon_3701030 .
obo:PHIPO_0001008 a rdfs:Class ;
rdfs:label "abnormal transport during vegetative growth"@en ;
rdfs:comment "A phenotype in which a specific transport process is abnormal in the vegetative growth phase of the life cycle." ;
rdfs:subClassOf obo:PHIPO_0000257 .
obo:CHEBI_64245 a rdfs:Class ;
rdfs:label "tunicamycin A1" ;
rdfs:comment "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 12-methyltridec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ;
rdfs:subClassOf obo:CHEBI_33838 .
obo:GO_0097154 a rdfs:Class ;
rdfs:label "GABAergic neuron differentiation" ;
rdfs:comment "The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030182 .
obo:CHEBI_65256 a rdfs:Class ;
rdfs:label "antimicrobial food preservative" ;
rdfs:comment "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." ;
rdfs:subClassOf obo:CHEBI_33281 , obo:CHEBI_65255 .
obo:GO_0043032 a rdfs:Class ;
rdfs:label "positive regulation of macrophage activation" ;
rdfs:comment "Any process that stimulates, induces or increases the rate of macrophage activation." ;
rdfs:subClassOf obo:GO_0002696 , obo:GO_0043030 , obo:GO_0065007 .
obo:CHEBI_35507 a rdfs:Class ;
rdfs:label "natural product fundamental parent" ;
rdfs:subClassOf obo:CHEBI_33245 .
obo:GO_0002792 a rdfs:Class ;
rdfs:label "negative regulation of peptide secretion" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion." ;
rdfs:subClassOf obo:GO_0002791 , obo:GO_0051048 , obo:GO_0065007 .
obo:GO_0043176 a rdfs:Class ;
rdfs:label "amine binding" ;
rdfs:comment "Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group." ;
rdfs:subClassOf obo:GO_0005488 .
obo:PHIPO_0001175 a rdfs:Class ;
rdfs:label "normal pathogen protein localization within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the localization of a pathogen protein in a host cell is normal." ;
rdfs:subClassOf obo:PHIPO_0000236 .
obo:GO_0032964 a rdfs:Class ;
rdfs:label "collagen biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0032963 .
obo:CL_4300358 a rdfs:Class ;
rdfs:label "subcortical astrocyte (Mmus)" ;
rdfs:comment "A transcriptomically defined type of astrocyte located predominantly in the ventral and posterior subcortical areas. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Cd38 (Mmus), Agt (Mmus), Itih3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:318 Astro-NT NN." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000127 .
obo:PHIPO_0000652 a rdfs:Class ;
rdfs:label "resistance to rapamycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to rapamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0007000 a rdfs:Class ;
rdfs:label "nucleolus organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." ;
rdfs:subClassOf obo:GO_0006997 , obo:GO_0016043 .
obo:GO_0048288 a rdfs:Class ;
rdfs:label "nuclear membrane fusion involved in karyogamy" ;
rdfs:comment "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei." ;
rdfs:subClassOf obo:GO_0000740 .
obo:GO_0007005 a rdfs:Class ;
rdfs:label "mitochondrion organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components." ;
rdfs:subClassOf obo:GO_0006996 , obo:GO_0016043 .
obo:GO_0007271 a rdfs:Class ;
rdfs:label "synaptic transmission, cholinergic" ;
rdfs:comment "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ;
rdfs:subClassOf obo:GO_0007268 .
obo:UBERON_0013149 a rdfs:Class ;
rdfs:label "hindbrain vesicle" ;
rdfs:comment "gives rise of 4th ventricle" ;
rdfs:subClassOf obo:UBERON_0013150 .
obo:GO_0072132 a rdfs:Class ;
rdfs:label "mesenchyme morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048729 .
a rdfs:Class ;
rdfs:label "TAGLN" ;
rdfs:subClassOf obo:SO_0000704 .
obo:UBERON_0002031 a rdfs:Class ;
rdfs:label "epithelium of bronchus" ;
rdfs:comment "An epithelium that is part of a bronchus [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0008397 .
obo:GO_0090138 a rdfs:Class ;
rdfs:label "regulation of actin cytoskeleton organization by cell-cell adhesion" ;
rdfs:comment "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ;
rdfs:subClassOf obo:GO_0032956 , obo:GO_0098609 .
obo:UBERON_0000489 a rdfs:Class ;
rdfs:label "cavitated compound organ" ;
rdfs:comment "Compound organ that contains one or more macroscopic anatomical spaces." ;
rdfs:subClassOf obo:UBERON_0003103 .
obo:CL_0000165 a rdfs:Class ;
rdfs:label "neuroendocrine cell" ;
rdfs:comment "A neuron that is capable of some hormone secretion in response to neuronal signals." ;
rdfs:subClassOf obo:CL_0000163 , obo:CL_0000527 , obo:CL_0000540 , obo:CL_0000710 , obo:CL_1100001 .
obo:CHEBI_29534 a rdfs:Class ;
rdfs:label "avermectin B1a" ;
rdfs:subClassOf obo:CHEBI_50344 .
obo:GO_0021953 a rdfs:Class ;
rdfs:label "central nervous system neuron differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0030182 .
obo:UBERON_0010032 a rdfs:Class ;
rdfs:label "anterior part of tongue" ;
rdfs:comment "The portion of the tongue in front of the terminal sulcus. At the apex, thin and narrow, it is directed forward against the lingual surfaces of the lower incisor teeth. It is derived primarily from the first pharyngeal arch." ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:UBERON_0007142 a rdfs:Class ;
rdfs:label "left internal carotid artery" ;
rdfs:comment "An internal carotid artery that branching_part_of a left common carotid artery plus branches." ;
rdfs:subClassOf obo:UBERON_0001532 .
obo:GO_0061557 a rdfs:Class ;
rdfs:label "trigeminal ganglion maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0061558 , obo:GO_0071695 .
obo:UBERON_0010339 a rdfs:Class ;
rdfs:label "1st arch mandibular mesenchyme from head mesenchyme" ;
rdfs:comment "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0009584 , obo:UBERON_0010341 .
obo:GO_0098633 a rdfs:Class ;
rdfs:label "collagen fibril binding" ;
rdfs:comment "Binding to a collagen fibril." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0050840 .
obo:CHEBI_24396 a rdfs:Class ;
rdfs:label "glycopeptide" ;
rdfs:comment "Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide." ;
rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_63299 .
obo:UBERON_6000004 a rdfs:Class ;
rdfs:label "panarthropod head" ;
rdfs:subClassOf obo:UBERON_0000033 .
obo:GO_0003275 a rdfs:Class ;
rdfs:label "apoptotic process involved in outflow tract morphogenesis" ;
rdfs:comment "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries." ;
rdfs:subClassOf obo:GO_0003278 , obo:GO_0006915 .
obo:CHEBI_17996 a rdfs:Class ;
rdfs:label "chloride" ;
rdfs:comment "A halide anion formed when chlorine picks up an electron to form an an anion." ;
rdfs:subClassOf obo:CHEBI_16042 , obo:CHEBI_33432 .
obo:GO_1903011 a rdfs:Class ;
rdfs:label "negative regulation of bone development" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of bone development." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 , obo:GO_1903010 .
obo:CHEBI_33261 a rdfs:Class ;
rdfs:label "organosulfur compound" ;
rdfs:comment "An organosulfur compound is a compound containing at least one carbon-sulfur bond." ;
rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_36962 .
obo:CHEBI_25477 a rdfs:Class ;
rdfs:label "naphthalenes" ;
rdfs:comment "Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings." ;
rdfs:subClassOf obo:CHEBI_33836 , obo:CHEBI_36785 .
obo:CHEBI_50344 a rdfs:Class ;
rdfs:label "avermectin" ;
rdfs:comment "Any of the macrolides obtained as fermentation products from the bacterium Streptomyces avermitilis and consisting of a 16-membered macrocyclic backbone that is fused both benzofuran and spiroketal functions and contains a disaccharide substituent. They have significant anthelmintic and insecticidal properties." ;
rdfs:subClassOf obo:CHEBI_25106 , obo:CHEBI_59779 .
obo:CHEBI_16914 a rdfs:Class ;
rdfs:label "salicylic acid" ;
rdfs:comment "A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves." ;
rdfs:subClassOf obo:CHEBI_25389 .
obo:CHEBI_87071 a rdfs:Class ;
rdfs:label "conazole antifungal drug" ;
rdfs:comment "Any conazole antifungal agent that has been used for the treatment of fungal infections in animals or humans." ;
rdfs:subClassOf obo:CHEBI_86323 .
obo:GO_0098935 a rdfs:Class ;
rdfs:label "dendritic transport" ;
rdfs:comment "The directed movement of organelles or molecules along microtubules in dendrites." ;
rdfs:subClassOf obo:GO_0008088 , obo:GO_0046907 .
obo:PHIPO_0001267 a rdfs:Class ;
rdfs:label "level of pathogen produced RNA within host phenotype"@en ;
rdfs:comment "A pathogen host interaction phenotype, which affects the level of pathogen produced RNA during host infection." ;
rdfs:subClassOf obo:PHIPO_0001197 .
obo:GO_0030198 a rdfs:Class ;
rdfs:label "extracellular matrix organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_0043062 , obo:GO_0045229 .
obo:GO_0060958 a rdfs:Class ;
rdfs:label "endocardial cell development" ;
rdfs:comment "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." ;
rdfs:subClassOf obo:GO_0001885 , obo:GO_0048856 , obo:GO_0055006 .
obo:PATO_0001162 a rdfs:Class ;
rdfs:label "increased concentration" ;
rdfs:comment "A concentration which is higher relative to the normal or average." ;
rdfs:subClassOf obo:PATO_0000470 , obo:PATO_0001159 , obo:PATO_0002305 .
obo:CHEBI_26400 a rdfs:Class ;
rdfs:label "purine ribonucleotide" ;
rdfs:comment "Any ribonucleotide that has a purine nucleobase." ;
rdfs:subClassOf obo:CHEBI_26395 , obo:CHEBI_26561 .
obo:UBERON_0000076 a rdfs:Class ;
rdfs:label "external ectoderm" ;
rdfs:comment "The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm." ;
rdfs:subClassOf obo:UBERON_0000490 , obo:UBERON_0005291 .
obo:CL_4023161 a rdfs:Class ;
rdfs:label "unipolar brush cell" ;
rdfs:comment "An excitatory glutamatergic interneuron found in the granular layer of the cerebellar cortex and also in the granule cell domain of the cochlear nucleus. Unipolar brush cells have a round or oval cell body with usually a single short dendrite that ends in a brush-like tuft of short dendrites unique to them known as dendrioles." ;
rdfs:subClassOf obo:CL_0000099 , obo:CL_0000679 .
obo:UBERON_0001918 a rdfs:Class ;
rdfs:label "endothelium of venule" ;
rdfs:comment "An endothelium that is part of a venule [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0004701 , obo:UBERON_0008339 .
obo:GO_0085030 a rdfs:Class ;
rdfs:label "mutualism" ;
rdfs:comment "An interaction between two organisms living together in more or less intimate association in a relationship in which both organisms benefit from each other." ;
rdfs:subClassOf obo:GO_0044403 .
obo:UBERON_0001649 a rdfs:Class ;
rdfs:label "glossopharyngeal nerve" ;
rdfs:comment "Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult)." ;
rdfs:subClassOf obo:UBERON_0001785 .
obo:PHIPO_0001187 a rdfs:Class ;
rdfs:label "obsolete functional host resistance gene absent" ;
rdfs:comment "A phenotype where ability of a host to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene, is absent." .
obo:UBERON_0012430 a rdfs:Class ;
rdfs:label "tunica fibrosa of eyeball" ;
rdfs:comment "The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth." ;
rdfs:subClassOf obo:UBERON_0004923 , obo:UBERON_0010314 .
obo:PHIPO_0000032 a rdfs:Class ;
rdfs:label "abnormal formation of pathogen penetration structure" ;
rdfs:comment "A single species pathogen growth phenotype in which the formation of the pathogen penetration structure is abnormal (i.e different than wild-type) when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000160 .
obo:PHIPO_0000363 a rdfs:Class ;
rdfs:label "absence of pathogen growth within host"@en ;
rdfs:comment "A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is absent." ;
rdfs:subClassOf obo:PHIPO_0000951 .
obo:GO_1900125 a rdfs:Class ;
rdfs:label "regulation of hyaluronan biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process." ;
rdfs:subClassOf obo:GO_0032885 , obo:GO_0065007 .
obo:CHEBI_35106 a rdfs:Class ;
rdfs:label "nitrogen hydride" ;
rdfs:subClassOf obo:CHEBI_35881 , obo:CHEBI_51143 .
obo:CHEBI_26167 a rdfs:Class ;
rdfs:label "polar amino acid" ;
rdfs:comment "Any amino acid whose side chain is capable of forming one or more hydrogen bonds." ;
rdfs:subClassOf obo:CHEBI_33709 .
obo:UBERON_0003580 a rdfs:Class ;
rdfs:label "lower respiratory tract connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0003570 .
obo:GO_0060535 a rdfs:Class ;
rdfs:label "trachea cartilage morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of cartilage in the trachea are generated and organized." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0060536 .
obo:CHEBI_33693 a rdfs:Class ;
rdfs:label "oxygen hydride" ;
rdfs:subClassOf obo:CHEBI_36902 .
obo:GO_1903119 a rdfs:Class ;
rdfs:label "protein localization to actin cytoskeleton" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton." ;
rdfs:subClassOf obo:GO_0008104 , obo:GO_0044380 .
obo:CL_4023121 a rdfs:Class ;
rdfs:label "sst chodl GABAergic interneuron" ;
rdfs:comment "A transcriptomically distinct sst GABAergic interneuron that also expresses Chodl. These neurons are rare and correspond to the only known interneurons with long-range projection." ;
rdfs:subClassOf obo:CL_4023017 .
obo:GO_1900006 a rdfs:Class ;
rdfs:label "positive regulation of dendrite development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dendrite development." ;
rdfs:subClassOf obo:GO_0010976 , obo:GO_0050773 , obo:GO_0051094 , obo:GO_0065007 .
obo:GO_0022603 a rdfs:Class ;
rdfs:label "regulation of anatomical structure morphogenesis" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:CL_4042023 a rdfs:Class ;
rdfs:label "striatal pthlh-expressing interneuron"@en ;
rdfs:comment "A GABAergic interneuron expressing PTHLH and PVALB that has its soma in a striatum. This GABAergic interneuron type presents a spatial expression gradient of PVALB in the mouse striatum." ;
rdfs:subClassOf obo:CL_0002613 , obo:CL_0011005 .
obo:CL_0019002 a rdfs:Class ;
rdfs:label "tracheobronchial chondrocyte"@en ;
rdfs:comment "Any chondrocyte that is part of the tracheobronchial tree." ;
rdfs:subClassOf obo:CL_0000138 .
obo:PHIPO_0000244 a rdfs:Class ;
rdfs:label "abnormal protein localization to nucleus"@en ;
rdfs:comment "A single organism phenotype in which the localization of a protein to the nucleus is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000239 .
obo:GO_0031641 a rdfs:Class ;
rdfs:label "regulation of myelination" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0051960 , obo:GO_0065007 .
obo:UBERON_0001980 a rdfs:Class ;
rdfs:label "arteriole" ;
rdfs:comment "The smallest division of the artery located between the muscular arteries and the capillaries[GO]." ;
rdfs:subClassOf obo:UBERON_0001981 , obo:UBERON_0003509 , obo:UBERON_8410081 .
obo:CHEBI_26561 a rdfs:Class ;
rdfs:label "ribonucleotide" ;
rdfs:subClassOf obo:CHEBI_26562 , obo:CHEBI_36976 .
obo:UBERON_0005882 a rdfs:Class ;
rdfs:label "neural tube alar plate" ;
rdfs:comment "The mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses." ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_1903829 a rdfs:Class ;
rdfs:label "positive regulation of protein localization" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of a protein localization." ;
rdfs:subClassOf obo:GO_0032880 , obo:GO_0048522 , obo:GO_0065007 .
obo:PHIPO_0000891 a rdfs:Class ;
rdfs:label "sensitive to hygromycin B"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to hygromycin B. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0006449 a rdfs:Class ;
rdfs:label "regulation of translational termination" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of translational termination." ;
rdfs:subClassOf obo:GO_0006417 , obo:GO_0043244 , obo:GO_0065007 .
obo:UBERON_0001678 a rdfs:Class ;
rdfs:label "temporal bone" ;
rdfs:comment "The large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous." ;
rdfs:subClassOf obo:UBERON_0008193 .
obo:GO_0044114 a rdfs:Class ;
rdfs:label "development of symbiont in host" ;
rdfs:comment "The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction." ;
rdfs:subClassOf obo:GO_0044111 .
obo:PHIPO_0001353 a rdfs:Class ;
rdfs:label "resistance to prothioconazole" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to prothioconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1903020 a rdfs:Class ;
rdfs:label "positive regulation of glycoprotein metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process." ;
rdfs:subClassOf obo:GO_0051247 , obo:GO_0065007 , obo:GO_1903018 .
obo:GO_0005575 a rdfs:Class ;
rdfs:label "cellular_component" ;
rdfs:comment "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." ;
rdfs:subClassOf obo:BFO_0000040 .
obo:UBERON_0005672 a rdfs:Class ;
rdfs:label "right lung endothelium" ;
rdfs:comment "An endothelium that is part of a right lung." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0003364 .
obo:UBERON_0003975 a rdfs:Class ;
rdfs:label "internal female genitalia" ;
rdfs:comment "The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina." ;
rdfs:subClassOf obo:UBERON_0003134 , obo:UBERON_0004175 .
obo:PHIPO_0000116 a rdfs:Class ;
rdfs:label "abolished pathogen growth after penetration of the barrier"@en ;
rdfs:comment "A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is abolished." ;
rdfs:subClassOf obo:PHIPO_0000031 .
obo:PHIPO_0000831 a rdfs:Class ;
rdfs:label "sensitive to triadimefon"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to triadimefon. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0007530 a rdfs:Class ;
rdfs:label "migrating mesenchyme population" ;
rdfs:comment "Mesenchymal cells that are migrating." ;
rdfs:subClassOf obo:UBERON_0003104 .
obo:UBERON_0008876 a rdfs:Class ;
rdfs:label "hypodermis skeletal muscle layer" ;
rdfs:comment "Any skeletal muscle organ in the hypodermis / superficial fascia." ;
rdfs:subClassOf obo:UBERON_0004253 , obo:UBERON_0014892 .
obo:CHEBI_37527 a rdfs:Class ;
rdfs:label "acid" ;
rdfs:comment "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:PHIPO_0000744 a rdfs:Class ;
rdfs:label "sensitive to virginiamycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to virginiamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PR_P13379 a rdfs:Class ;
rdfs:label "T-cell surface glycoprotein CD5 (mouse)" ;
rdfs:comment "A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001839 , obo:PR_000029032 .
obo:UBERON_0007823 a rdfs:Class ;
rdfs:label "appendage girdle region" ;
rdfs:comment "An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc)." ;
rdfs:subClassOf obo:UBERON_0000475 .
obo:GO_0007113 a rdfs:Class ;
rdfs:label "endomitotic cell cycle" ;
rdfs:comment "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell." ;
rdfs:subClassOf obo:GO_0000278 .
obo:GO_0006954 a rdfs:Class ;
rdfs:label "inflammatory response" ;
rdfs:comment "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." ;
rdfs:subClassOf obo:GO_0006952 .
obo:UBERON_0006283 a rdfs:Class ;
rdfs:label "future cardiac ventricle" ;
rdfs:comment "Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:PHIPO_0000704 a rdfs:Class ;
rdfs:label "resistance to lincomycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to lincomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0005720 a rdfs:Class ;
rdfs:label "hindbrain venous system" ;
rdfs:comment "A venous system that is part of a hindbrain." ;
rdfs:subClassOf obo:UBERON_0004582 .
obo:GO_0021761 a rdfs:Class ;
rdfs:label "limbic system development" ;
rdfs:comment "The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:CHEBI_38532 a rdfs:Class ;
rdfs:label "hydrazone" ;
rdfs:comment "Compounds having the structure R2C=NNR2, formally derived from aldehydes or ketones by replacing =O by =NNH2 (or substituted analogues)." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:UBERON_0034944 a rdfs:Class ;
rdfs:label "zone of organ" ;
rdfs:subClassOf obo:UBERON_0000064 .
obo:CHEBI_87204 a rdfs:Class ;
rdfs:label "pyrimidine antifungal agent" ;
rdfs:comment "A member of the class of pyrimidines that has significant antifungal properties." ;
rdfs:subClassOf obo:CHEBI_39447 .
obo:GO_0014002 a rdfs:Class ;
rdfs:label "astrocyte development" ;
rdfs:comment "The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function." ;
rdfs:subClassOf obo:GO_0021782 , obo:GO_0032502 .
obo:UBERON_0006218 a rdfs:Class ;
rdfs:label "common atrial chamber" ;
rdfs:subClassOf obo:UBERON_0002050 .
obo:GO_0098796 a rdfs:Class ;
rdfs:label "membrane protein complex" ;
rdfs:comment "Any protein complex that is part of a membrane." ;
rdfs:subClassOf obo:GO_0032991 .
obo:GO_0055003 a rdfs:Class ;
rdfs:label "cardiac myofibril assembly" ;
rdfs:comment "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0030239 .
obo:GO_2000766 a rdfs:Class ;
rdfs:label "negative regulation of cytoplasmic translation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation." ;
rdfs:subClassOf obo:GO_0017148 , obo:GO_0065007 , obo:GO_2000765 .
obo:GO_2001018 a rdfs:Class ;
rdfs:label "negative regulation of retrograde axon cargo transport" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport." ;
rdfs:subClassOf obo:GO_0032387 , obo:GO_0065007 , obo:GO_2001017 .
obo:GO_0035240 a rdfs:Class ;
rdfs:label "dopamine binding" ;
rdfs:comment "Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0043169 , obo:GO_1901338 .
obo:CL_4304384 a rdfs:Class ;
rdfs:label "hypothalamic gonadotropin-releasing hormone neuron (Mmus)" ;
rdfs:comment "A hypothalamic gonadotropin-releasing hormone neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gnrh1 (Mmus). It is glutamatergic (inferred from expression of Gad1, Slc17a6, Gad2). These cells are located in the Hypothalamus, Olfactory areas, Pallidum, brain , in or close to the regions: Lateral septal nucleus, rostral (rostroventral) part, Medial septal nucleus, Diagonal band nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:2564 HY Gnrh1 Glut_1." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000679 , obo:CL_0011111 .
obo:UBERON_0036553 a rdfs:Class ;
rdfs:label "wall of synovial tendon sheath" ;
rdfs:subClassOf obo:UBERON_0000042 , obo:UBERON_0000060 .
obo:GO_0021794 a rdfs:Class ;
rdfs:label "thalamus development" ;
rdfs:comment "The process in which the thalamus changes over time, from its initial formation to its mature state." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0048880 a rdfs:Class ;
rdfs:label "sensory system development" ;
rdfs:comment "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." ;
rdfs:subClassOf obo:GO_0048731 , obo:GO_0048856 .
obo:CHEBI_48359 a rdfs:Class ;
rdfs:label "protophilic solvent" ;
rdfs:comment "Solvent that is capable of acting as a hydron (proton) acceptor." ;
rdfs:subClassOf obo:CHEBI_39142 , obo:CHEBI_48354 .
obo:GO_1900451 a rdfs:Class ;
rdfs:label "positive regulation of glutamate receptor signaling pathway" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway." ;
rdfs:subClassOf obo:GO_0009967 , obo:GO_0065007 , obo:GO_1900449 .
obo:GO_1903335 a rdfs:Class ;
rdfs:label "regulation of vacuolar transport" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vacuolar transport." ;
rdfs:subClassOf obo:GO_0032386 , obo:GO_0065007 .
obo:CHEBI_35356 a rdfs:Class ;
rdfs:label "dicarboximide" ;
rdfs:comment "An imide in which the two acyl substituents on nitrogen are carboacyl groups." ;
rdfs:subClassOf obo:CHEBI_24782 .
obo:GO_1901211 a rdfs:Class ;
rdfs:label "negative regulation of cardiac chamber formation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation." ;
rdfs:subClassOf obo:GO_0051093 , obo:GO_0065007 , obo:GO_1901210 .
obo:GO_0009527 a rdfs:Class ;
rdfs:label "plastid outer membrane" ;
rdfs:comment "The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope." ;
rdfs:subClassOf obo:GO_0016020 , obo:GO_0031968 , obo:GO_0042170 .
obo:CHEBI_19129 a rdfs:Class ;
rdfs:label "11alpha-hydroxy steroid" ;
rdfs:subClassOf obo:CHEBI_36841 .
obo:GO_0170040 a rdfs:Class ;
rdfs:label "proteinogenic amino acid catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0046395 , obo:GO_0170039 .
obo:UBERON_0003585 a rdfs:Class ;
rdfs:label "dermis connective tissue" ;
rdfs:comment "A portion of connective tissue that is part of a dermis [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002384 , obo:UBERON_0010313 .
obo:CHEBI_24079 a rdfs:Class ;
rdfs:label "formamides" ;
rdfs:comment "Amides with the general formula R1R2NCHO (R1 and R2 can be H)." ;
rdfs:subClassOf obo:CHEBI_37622 .
obo:UBERON_0004698 a rdfs:Class ;
rdfs:label "vena cava endothelium" ;
rdfs:comment "An endothelium that is part of a vena cava [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001919 , obo:UBERON_0001986 .
obo:GO_0097084 a rdfs:Class ;
rdfs:label "vascular associated smooth muscle cell development" ;
rdfs:comment "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0055001 .
obo:CHEBI_26835 a rdfs:Class ;
rdfs:label "sulfur molecular entity" ;
rdfs:subClassOf obo:CHEBI_33304 .
obo:UBERON_0000328 a rdfs:Class ;
rdfs:label "gut wall" ;
rdfs:comment "The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity)." ;
rdfs:subClassOf obo:UBERON_0000060 .
obo:GO_0048754 a rdfs:Class ;
rdfs:label "branching morphogenesis of an epithelial tube" ;
rdfs:comment "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder." ;
rdfs:subClassOf obo:GO_0001763 , obo:GO_0035239 , obo:GO_0061138 .
obo:GO_0010482 a rdfs:Class ;
rdfs:label "regulation of epidermal cell division" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis." ;
rdfs:subClassOf obo:GO_0051302 , obo:GO_0065007 .
obo:PHIPO_0000592 a rdfs:Class ;
rdfs:label "resistance to fludioxonil"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to fludioxonil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0060974 a rdfs:Class ;
rdfs:label "cell migration involved in heart formation" ;
rdfs:comment "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells." ;
rdfs:subClassOf obo:GO_0016477 , obo:GO_0060973 .
obo:PATO_0001555 a rdfs:Class ;
rdfs:label "has number of" ;
rdfs:comment "The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts." ;
rdfs:subClassOf obo:PATO_0000070 .
obo:GO_0002618 a rdfs:Class ;
rdfs:label "positive regulation of macrophage antigen processing and presentation" ;
rdfs:comment "Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002579 , obo:GO_0002616 , obo:GO_0065007 .
obo:GO_0045037 a rdfs:Class ;
rdfs:label "protein import into chloroplast stroma" ;
rdfs:comment "The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import." ;
rdfs:subClassOf obo:GO_0055085 , obo:GO_0071806 , obo:GO_0072596 .
obo:UBERON_0004924 a rdfs:Class ;
rdfs:label "submucosa of pharynx" ;
rdfs:comment "The tissue underlying the tunica mucosa of the pharynx." ;
rdfs:subClassOf obo:UBERON_0000009 , obo:UBERON_0004777 , obo:UBERON_0018257 .
obo:GO_1900017 a rdfs:Class ;
rdfs:label "positive regulation of cytokine production involved in inflammatory response" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response." ;
rdfs:subClassOf obo:GO_0001819 , obo:GO_0065007 , obo:GO_1900015 .
obo:GO_0002469 a rdfs:Class ;
rdfs:label "myeloid dendritic cell antigen processing and presentation" ;
rdfs:comment "The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." ;
rdfs:subClassOf obo:GO_0002468 , obo:GO_0019882 .
obo:PHIPO_0000668 a rdfs:Class ;
rdfs:label "resistance to cefoxitin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cefoxitin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_30256 a rdfs:Class ;
rdfs:label "thiocarbonyl group" ;
rdfs:subClassOf obo:CHEBI_51422 .
obo:CHEBI_87066 a rdfs:Class ;
rdfs:label "carbanilate fungicide" ;
rdfs:comment "Any carbamate fungicide that has a phenyl or substituted-phenyl group attached to the nitrogen of the carbamate group." ;
rdfs:subClassOf obo:CHEBI_87061 .
obo:UBERON_0004258 a rdfs:Class ;
rdfs:label "back blood vessel" ;
rdfs:comment "A blood vessel that is part of a back [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:UBERON_0010227 a rdfs:Class ;
rdfs:label "future cardiac atrium" ;
rdfs:comment "Multi-tissue structure that is part of the heart tube and will become the cardiac atrium." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_1902684 a rdfs:Class ;
rdfs:label "negative regulation of receptor localization to synapse" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0065007 , obo:GO_1902683 .
obo:GO_1902903 a rdfs:Class ;
rdfs:label "regulation of supramolecular fiber organization" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." ;
rdfs:subClassOf obo:GO_0051128 , obo:GO_0065007 .
obo:GO_0014023 a rdfs:Class ;
rdfs:label "neural rod formation" ;
rdfs:comment "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts." ;
rdfs:subClassOf obo:GO_0048646 .
obo:PATO_0002001 a rdfs:Class ;
rdfs:label "has fewer parts of type" ;
rdfs:comment "The bearer of this quality has_part < n AND has_part > 0 of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly." ;
rdfs:subClassOf obo:PATO_0001997 , obo:PATO_0001999 , obo:PATO_0002303 .
obo:GO_0021586 a rdfs:Class ;
rdfs:label "pons maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:CHEBI_24068 a rdfs:Class ;
rdfs:label "fluoroamino acid" ;
rdfs:comment "An organofluorine compound that consists of an amino acid substituted by a fluoro group." ;
rdfs:subClassOf obo:CHEBI_24470 , obo:CHEBI_37143 .
obo:GO_0044743 a rdfs:Class ;
rdfs:label "protein transmembrane import into intracellular organelle" ;
rdfs:comment "The directed movement of proteins into an intracellular organelle, across a membrane." ;
rdfs:subClassOf obo:GO_0010496 , obo:GO_0046907 , obo:GO_0065002 , obo:GO_0072594 .
obo:CHEBI_36338 a rdfs:Class ;
rdfs:label "lepton" ;
rdfs:comment "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." ;
rdfs:subClassOf obo:CHEBI_33233 , obo:CHEBI_36340 .
obo:UBERON_0004348 a rdfs:Class ;
rdfs:label "optic eminence" ;
rdfs:comment "The embryonic structure that gives rise to the corneal ectoderm." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:CHEBI_23116 a rdfs:Class ;
rdfs:label "chlorine atom" ;
rdfs:subClassOf obo:CHEBI_24473 .
obo:PHIPO_0000343 a rdfs:Class ;
rdfs:label "delayed pathogen cell to cell migration within host"@en ;
rdfs:comment "A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism happens later than normal." ;
rdfs:subClassOf obo:PHIPO_0000334 .
obo:GO_1905553 a rdfs:Class ;
rdfs:label "regulation of blood vessel branching" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of blood vessel branching." ;
rdfs:subClassOf obo:GO_0045765 , obo:GO_0060688 , obo:GO_0065007 , obo:GO_1905330 .
obo:CHEBI_35186 a rdfs:Class ;
rdfs:label "terpene" ;
rdfs:comment "A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]." ;
rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_24913 .
obo:CHEBI_70868 a rdfs:Class ;
rdfs:label "antileishmanial agent" ;
rdfs:comment "An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania." ;
rdfs:subClassOf obo:CHEBI_35820 .
obo:PHIPO_0000698 a rdfs:Class ;
rdfs:label "resistance to trichostatin A"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to trichostatin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_1904989 a rdfs:Class ;
rdfs:label "positive regulation of endothelial cell activation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of endothelial cell activation." ;
rdfs:subClassOf obo:GO_0050867 , obo:GO_0065007 , obo:GO_1904987 .
obo:CL_0000119 a rdfs:Class ;
rdfs:label "cerebellar Golgi cell" ;
rdfs:comment "Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004." ;
rdfs:subClassOf obo:CL_4023057 .
obo:UBERON_0011642 a rdfs:Class ;
rdfs:label "oral epithelium from ectoderm" ;
rdfs:comment "An epithelium that develops_from a ectoderm and is part of a oral epithelium." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0000490 , obo:UBERON_0002424 , obo:UBERON_0010371 .
obo:GO_0016241 a rdfs:Class ;
rdfs:label "regulation of macroautophagy" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of macroautophagy." ;
rdfs:subClassOf obo:GO_0010506 , obo:GO_0065007 .
obo:CHEBI_59285 a rdfs:Class ;
rdfs:label "EC 1.14.13.132 (squalene monooxygenase) inhibitor" ;
rdfs:comment "An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132)." ;
rdfs:subClassOf obo:CHEBI_76841 .
obo:UBERON_0000475 a rdfs:Class ;
rdfs:label "organism subdivision" ;
rdfs:comment "Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:UBERON_0001584 a rdfs:Class ;
rdfs:label "left subclavian artery" ;
rdfs:comment "The subclavian artery that supplies the left pectoral appendage." ;
rdfs:subClassOf obo:UBERON_0001533 , obo:UBERON_0015212 .
obo:CHEBI_25728 a rdfs:Class ;
rdfs:label "osmolyte" ;
rdfs:comment "A solute used by a cell under water stress to maintain cell volume." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:GO_0060039 a rdfs:Class ;
rdfs:label "pericardium development" ;
rdfs:comment "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery." ;
rdfs:subClassOf obo:GO_0048856 , obo:GO_0060429 .
obo:CHEBI_23019 a rdfs:Class ;
rdfs:label "carbonyl group" ;
rdfs:subClassOf obo:CHEBI_51422 .
obo:CHEBI_50103 a rdfs:Class ;
rdfs:label "excitatory amino acid agonist" ;
rdfs:comment "An agent that binds to and activates excitatory amino acid receptors." ;
rdfs:subClassOf obo:CHEBI_35942 .
obo:GO_0021846 a rdfs:Class ;
rdfs:label "cell proliferation in forebrain" ;
rdfs:comment "The creation of greater cell numbers in the forebrain due to cell division of progenitor cells." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0061351 .
obo:UBERON_0006567 a rdfs:Class ;
rdfs:label "right ventricle myocardium" ;
rdfs:comment "A myocardium that is part of a right ventricle of a heart." ;
rdfs:subClassOf obo:UBERON_0001083 .
obo:PHIPO_0000797 a rdfs:Class ;
rdfs:label "sensitive to caspofungin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to caspofungin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1904750 a rdfs:Class ;
rdfs:label "negative regulation of protein localization to nucleolus" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1900181 , obo:GO_1904749 .
obo:UBERON_0000073 a rdfs:Class ;
rdfs:label "regional part of nervous system" ;
rdfs:comment "Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS." ;
rdfs:subClassOf obo:UBERON_0000481 .
obo:GO_0070977 a rdfs:Class ;
rdfs:label "bone maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0048799 .
obo:GO_0048635 a rdfs:Class ;
rdfs:label "negative regulation of muscle organ development" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." ;
rdfs:subClassOf obo:GO_0048634 , obo:GO_0051093 , obo:GO_0051241 , obo:GO_0065007 .
obo:PR_Q61391 a rdfs:Class ;
rdfs:label "neprilysin (mouse)" ;
rdfs:comment "A neprilysin that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000001898 , obo:PR_000029032 .
obo:UBERON_0010252 a rdfs:Class ;
rdfs:label "1st arch mandibular mesenchyme from neural crest" ;
rdfs:comment "Mesenchyme that develops_from a neural crest and is part of a 1st arch mandibular mesenchyme." ;
rdfs:subClassOf obo:UBERON_0003104 , obo:UBERON_0009584 , obo:UBERON_0010259 .
obo:CHEBI_35627 a rdfs:Class ;
rdfs:label "beta-lactam" ;
rdfs:comment "A lactam in which the amide bond is contained within a four-membered ring, which includes the amide nitrogen and the carbonyl carbon." ;
rdfs:subClassOf obo:CHEBI_24995 .
obo:CHEBI_51086 a rdfs:Class ;
rdfs:label "chemical role" ;
rdfs:comment "A role played by the molecular entity or part thereof within a chemical context." ;
rdfs:subClassOf obo:CHEBI_50906 .
obo:CHEBI_26078 a rdfs:Class ;
rdfs:label "phosphoric acid" ;
rdfs:comment "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." ;
rdfs:subClassOf obo:CHEBI_59698 .
obo:UBERON_0000925 a rdfs:Class ;
rdfs:label "endoderm" ;
rdfs:comment "Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut." ;
rdfs:subClassOf obo:UBERON_0000923 .
obo:PHIPO_0000299 a rdfs:Class ;
rdfs:label "obsolete abnormal dissemination of pathogen sexual product" .
obo:GO_1905305 a rdfs:Class ;
rdfs:label "negative regulation of cardiac myofibril assembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly." ;
rdfs:subClassOf obo:GO_0051494 , obo:GO_0065007 , obo:GO_1902116 , obo:GO_1902904 , obo:GO_1905304 , obo:GO_2000726 .
obo:GO_1904935 a rdfs:Class ;
rdfs:label "positive regulation of cell proliferation in midbrain" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1904933 , obo:GO_2000179 .
obo:CL_1001568 a rdfs:Class ;
rdfs:label "pulmonary artery endothelial cell" ;
rdfs:comment "Any endothelial cell of vascular tree that is part of some pulmonary artery." ;
rdfs:subClassOf obo:CL_0002139 , obo:CL_1000413 .
obo:GO_0021537 a rdfs:Class ;
rdfs:label "telencephalon development" ;
rdfs:comment "The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived." ;
rdfs:subClassOf obo:GO_0048856 .
obo:PATO_0002318 a rdfs:Class ;
rdfs:label "superelliptic" ;
rdfs:comment "A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt" ;
rdfs:subClassOf obo:PATO_0002006 .
obo:PHIPO_0001141 a rdfs:Class ;
rdfs:label "obsolete host effector triggered immunity signaling induced hypersensitive response activated by pathogen" ;
rdfs:comment "A cell signaling pathway phenotype where the host effector-triggered immunity signaling pathway is induced by a pathogen to activate a plant hypersensitive response and induce necrosis." .
obo:CHEBI_77736 a rdfs:Class ;
rdfs:label "(S)-verapamil" ;
rdfs:comment "A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has S configuration." ;
rdfs:subClassOf obo:CHEBI_77733 .
obo:UBERON_0035552 a rdfs:Class ;
rdfs:label "deep vein" ;
rdfs:comment "A blood vessel carrying deoxygenated blood far beneath the skin usually accompanying an artery." ;
rdfs:subClassOf obo:UBERON_0001638 .
obo:GO_0042420 a rdfs:Class ;
rdfs:label "dopamine catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0042417 , obo:GO_0042424 .
obo:CHEBI_35605 a rdfs:Class ;
rdfs:label "carbon oxoacid" ;
rdfs:subClassOf obo:CHEBI_24833 , obo:CHEBI_36963 .
obo:PHIPO_0001086 a rdfs:Class ;
rdfs:label "abnormal cellular component assembly"@en ;
rdfs:comment "A single species cellular process phenotype in which any process of cellular component assembly at the cellular level is abnormal." ;
rdfs:subClassOf obo:PHIPO_0000400 .
obo:UBERON_0007241 a rdfs:Class ;
rdfs:label "tunica adventitia of vein" ;
rdfs:comment "A tunica adventitia that is part of a vein." ;
rdfs:subClassOf obo:UBERON_0005734 .
obo:CHEBI_35622 a rdfs:Class ;
rdfs:label "thiazolidines" ;
rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 , obo:CHEBI_38106 .
obo:PHIPO_0000726 a rdfs:Class ;
rdfs:label "sensitive to chloramphenicol"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to chloramphenicol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CL_0000163 a rdfs:Class ;
rdfs:label "endocrine cell" ;
rdfs:comment "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0000151 , obo:CL_0000255 .
obo:PATO_0001987 a rdfs:Class ;
rdfs:label "saccular" ;
rdfs:comment "A structural quality inhering in a bearer by virtue of the bearer's having a three dimensional cavity with a narrow or no opening, and often containing an anatomical substance." ;
rdfs:subClassOf obo:PATO_0002014 .
obo:GO_0045582 a rdfs:Class ;
rdfs:label "positive regulation of T cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of T cell differentiation." ;
rdfs:subClassOf obo:GO_0045580 , obo:GO_0045621 , obo:GO_0050870 , obo:GO_0065007 .
obo:CHEBI_25491 a rdfs:Class ;
rdfs:label "nematicide" ;
rdfs:comment "A substance used to destroy pests of the phylum Nematoda (roundworms)." ;
rdfs:subClassOf obo:CHEBI_25944 .
obo:PATO_0001708 a rdfs:Class ;
rdfs:label "1-D extent" ;
rdfs:comment "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension." ;
rdfs:subClassOf obo:PATO_0000117 .
obo:PHIPO_0001242 a rdfs:Class ;
rdfs:label "pathogen binding of chitin with host present"@en ;
rdfs:comment "A molecular function phenotype in which the binding of chitin or chitin fragments by the pathogen during host colonization is present." ;
rdfs:subClassOf obo:PHIPO_0000164 .
obo:GO_0060126 a rdfs:Class ;
rdfs:label "somatotropin secreting cell differentiation" ;
rdfs:comment "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin." ;
rdfs:subClassOf obo:GO_0030154 .
obo:GO_0061074 a rdfs:Class ;
rdfs:label "regulation of neural retina development" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." ;
rdfs:subClassOf obo:GO_0050793 , obo:GO_0065007 .
obo:PHIPO_0000955 a rdfs:Class ;
rdfs:label "abolished formation of pathogen penetration structure when near host"@en ;
rdfs:comment "A pathogen growth with host phenotype in which the ability of the pathogen to form a specialized penetration structure is abolished." ;
rdfs:subClassOf obo:PHIPO_0000369 .
obo:UBERON_0005283 a rdfs:Class ;
rdfs:label "tela choroidea" ;
rdfs:comment "A structure found in the walls of the ventricles of the brain, consisting of part of the meninges (pia mater in mammals) plus ependyma[cjm]." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:UBERON_0007277 a rdfs:Class ;
rdfs:label "presumptive hindbrain" ;
rdfs:comment "The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:PHIPO_0000327 a rdfs:Class ;
rdfs:label "resistance to cyproconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cypronazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0003547 a rdfs:Class ;
rdfs:label "brain meninx" ;
rdfs:comment "A meninx that is part of a brain [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002360 .
obo:PATO_0000573 a rdfs:Class ;
rdfs:label "increased length" ;
rdfs:comment "A length quality which is relatively large." ;
rdfs:subClassOf obo:PATO_0000122 , obo:PATO_0000586 .
obo:GO_0005829 a rdfs:Class ;
rdfs:label "cytosol" ;
rdfs:comment "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0000959 a rdfs:Class ;
rdfs:label "mitochondrial RNA metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ;
rdfs:subClassOf obo:GO_0016070 .
obo:PHIPO_0000512 a rdfs:Class ;
rdfs:label "obsolete pathogen host interaction host tissue phenotype" ;
rdfs:comment "A pathogen host interaction phenotype that is observed at the level of a host tissue (eg leaf, inflorescence, ear or kidney)." .
obo:CHEBI_46416 a rdfs:Class ;
rdfs:label "virginiamycin S1" ;
rdfs:comment "A cyclodepsipeptide that is N-(3-hydroxypicolinoyl)-L-threonyl-D-α-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine in which the carboxy group of the 2-phenylglycine moiety has undergone formal intramolecular condensation with the hydroxy group of the N-(3-hydroxypicolinoyl)-L-threonyl to give the corresponding 19-membered ring lactone. It is one of the two major components of the antibacterial drug virginiamycin, produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others." ;
rdfs:subClassOf obo:CHEBI_25105 , obo:CHEBI_35213 .
obo:PHIPO_0000136 a rdfs:Class ;
rdfs:label "decreased protein-protein interaction"@en ;
rdfs:comment "A single species molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." ;
rdfs:subClassOf obo:PHIPO_0000133 .
obo:PHIPO_0000385 a rdfs:Class ;
rdfs:label "resistance to oxolinic acid"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to oxolinic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_50185 a rdfs:Class ;
rdfs:label "fatty acid synthesis inhibitor" ;
rdfs:comment "Any pathway inhibitor that inhibits the synthesis of fatty acids." ;
rdfs:subClassOf obo:CHEBI_76932 .
obo:PHIPO_0000894 a rdfs:Class ;
rdfs:label "sensitive to prochloraz"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to prochloraz. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0070482 a rdfs:Class ;
rdfs:label "response to oxygen levels" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." ;
rdfs:subClassOf obo:GO_0009628 .
obo:UBERON_0005742 a rdfs:Class ;
rdfs:label "adventitia" ;
rdfs:comment "An outermost connective tissue covering of an organ, vessel, or other structure[WP]." ;
rdfs:subClassOf obo:UBERON_0004923 .
obo:CL_0000746 a rdfs:Class ;
rdfs:label "cardiac muscle cell" ;
rdfs:comment "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." ;
rdfs:subClassOf obo:CL_0000187 , obo:CL_0000737 , obo:CL_0002494 .
obo:UBERON_0004247 a rdfs:Class ;
rdfs:label "bone of dorsum" ;
rdfs:comment "A bone that is part of the dorsal region of an animal." ;
rdfs:subClassOf obo:UBERON_0001474 , obo:UBERON_0005174 .
obo:PHIPO_0001454 a rdfs:Class ;
rdfs:label "increased protein phosphorylation"@en ;
rdfs:comment "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a higher extent than normal." ;
rdfs:subClassOf obo:PHIPO_0001119 .
obo:GO_0006259 a rdfs:Class ;
rdfs:label "DNA metabolic process" ;
rdfs:comment "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides." ;
rdfs:subClassOf obo:GO_0008152 , obo:GO_0090304 .
obo:GO_0099546 a rdfs:Class ;
rdfs:label "protein catabolic process, modulating synaptic transmission" ;
rdfs:comment "Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0140246 .
obo:PHIPO_0000730 a rdfs:Class ;
rdfs:label "sensitive to sulfadimethoxine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulfadimethoxine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_4167 a rdfs:Class ;
rdfs:label "D-glucopyranose" ;
rdfs:comment "A glucopyranose having D-configuration." ;
rdfs:subClassOf obo:CHEBI_17634 , obo:CHEBI_37661 .
obo:CHEBI_59780 a rdfs:Class ;
rdfs:label "cyclic hemiketal" ;
rdfs:comment "A hemiacetal having the structure R2C(OH)OR (R ≠ H), derived from a ketone by formal addition of an alcohol to the carbonyl group. The term 'cyclic hemiketals', once abandoned by IUPAC, has been reinstated as a subclass of hemiacetals." ;
rdfs:subClassOf obo:CHEBI_38131 , obo:CHEBI_59772 .
obo:GO_0090150 a rdfs:Class ;
rdfs:label "establishment of protein localization to membrane" ;
rdfs:comment "The directed movement of a protein to a specific location in a membrane." ;
rdfs:subClassOf obo:GO_0045184 , obo:GO_0072657 .
obo:PHIPO_0000805 a rdfs:Class ;
rdfs:label "sensitive to colistin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to colistin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_33743 a rdfs:Class ;
rdfs:label "manganese group molecular entity" ;
rdfs:subClassOf obo:CHEBI_33676 .
obo:PR_000032533 a rdfs:Class ;
rdfs:label "LIM/homeobox protein Lhx6" ;
rdfs:comment "A protein that is a translation product of the human LHX6 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:UBERON_0020358 a rdfs:Class ;
rdfs:label "accessory XI nerve nucleus" ;
rdfs:comment "The spinal accessory nucleus lies within the cervical spinal cord (C1-C5) in the ventral horn. The nucleus ambiguus is classically said to provide the 'cranial component' of the accessory nerve. However, the very existence of this cranial component has been recently questioned and seen as contributing exclusively to the vagus nerve. The terminology continues to be used in describing both human anatomy, and that of other animals." ;
rdfs:subClassOf obo:UBERON_0000126 , obo:UBERON_0007635 .
obo:GO_0043228 a rdfs:Class ;
rdfs:label "membraneless organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." ;
rdfs:subClassOf obo:GO_0043226 .
obo:GO_1905770 a rdfs:Class ;
rdfs:label "regulation of mesodermal cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of mesodermal cell differentiation." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:PHIPO_0000663 a rdfs:Class ;
rdfs:label "resistance to difenoconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to difenoconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001014 a rdfs:Class ;
rdfs:label "increased level of host defense-induced callose deposition"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of host produced callose deposition usually present during infection is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0001196 .
obo:NCBITaxon_40674 a rdfs:Class ;
rdfs:label "Mammalia" ;
rdfs:subClassOf obo:NCBITaxon_32524 .
obo:GO_0061081 a rdfs:Class ;
rdfs:label "positive regulation of myeloid leukocyte cytokine production involved in immune response" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response." ;
rdfs:subClassOf obo:GO_0002720 , obo:GO_0065007 .
obo:CHEBI_48975 a rdfs:Class ;
rdfs:label "substituted aniline" ;
rdfs:subClassOf obo:CHEBI_22562 .
obo:CHEBI_53657 a rdfs:Class ;
rdfs:label "cefazolin(1-)" ;
rdfs:comment "A cephalosporin carboxylic acid anion having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups, formed by proton loss from the carboxy group of cefazolin." ;
rdfs:subClassOf obo:CHEBI_52440 .
obo:CHEBI_51447 a rdfs:Class ;
rdfs:label "organic univalent group" ;
rdfs:subClassOf obo:CHEBI_33247 .
obo:GO_1900141 a rdfs:Class ;
rdfs:label "regulation of oligodendrocyte apoptotic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process." ;
rdfs:subClassOf obo:GO_0034350 , obo:GO_0065007 .
obo:GO_2001200 a rdfs:Class ;
rdfs:label "positive regulation of dendritic cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902107 , obo:GO_2001198 .
obo:GO_2000279 a rdfs:Class ;
rdfs:label "negative regulation of DNA biosynthetic process" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process." ;
rdfs:subClassOf obo:GO_0010558 , obo:GO_0051053 , obo:GO_0065007 , obo:GO_2000278 .
obo:CHEBI_43474 a rdfs:Class ;
rdfs:label "hydrogenphosphate" ;
rdfs:comment "A phosphate ion that is the conjugate base of dihydrogenphosphate." ;
rdfs:subClassOf obo:CHEBI_35780 , obo:CHEBI_79388 .
obo:PHIPO_0000845 a rdfs:Class ;
rdfs:label "sensitive to meropenem"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to meropenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000819 .
obo:PHIPO_0001069 a rdfs:Class ;
rdfs:label "death of host organism with pathogen"@en ;
rdfs:comment "A host organism viability phenotype where the host organism death is accelerated by the pathogen." ;
rdfs:subClassOf obo:PHIPO_0001070 .
obo:PHIPO_0000560 a rdfs:Class ;
rdfs:label "resistance to clindamycin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to clindamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0007214 a rdfs:Class ;
rdfs:label "gamma-aminobutyric acid signaling pathway" ;
rdfs:comment "The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell." ;
rdfs:subClassOf obo:GO_0007267 .
obo:CHEBI_33671 a rdfs:Class ;
rdfs:label "heteropolycyclic compound" ;
rdfs:comment "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." ;
rdfs:subClassOf obo:CHEBI_33635 , obo:CHEBI_5686 .
obo:UBERON_0035118 a rdfs:Class ;
rdfs:label "material entity in digestive tract" ;
rdfs:comment "Any material entity that is located in the digestive tract. This includes undigested food and liquid as well as unexcreted waste products. It also includes other entities such as ingested stones used to aid digestion. Any microbial cells or cell populations are also included." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:CHEBI_58950 a rdfs:Class ;
rdfs:label "very long-chain fatty acid anion" ;
rdfs:comment "Any fatty acid anion with a chain length greater than C22." ;
rdfs:subClassOf obo:CHEBI_28868 .
obo:PHIPO_0000003 a rdfs:Class ;
rdfs:label "tissue phenotype" ;
rdfs:comment "A single organism phenotype that is observed at the level of a tissue (eg leaf, inflorescence, ear or kidney)." ;
rdfs:subClassOf obo:PHIPO_0000402 .
obo:UBERON_0000085 a rdfs:Class ;
rdfs:label "morula" ;
rdfs:comment "A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum." ;
rdfs:subClassOf obo:UBERON_0000922 .
obo:CHEBI_38500 a rdfs:Class ;
rdfs:label "EC 1.9.3.1 (cytochrome c oxidase) inhibitor" ;
rdfs:comment "An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1)." ;
rdfs:subClassOf obo:CHEBI_25355 , obo:CHEBI_76870 .
obo:PHIPO_0000208 a rdfs:Class ;
rdfs:label "obsolete decreased duration of pathogen host protein-protein interaction" ;
rdfs:comment "A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs for a shorter time than normal." .
obo:PHIPO_0000980 a rdfs:Class ;
rdfs:label "normal sexual spore morphology"@en ;
rdfs:comment "A reproductive phenotype where the morphology of the sexual spore is normal (FAO:0000017). The product of meiosis." ;
rdfs:subClassOf obo:PHIPO_0000046 .
obo:PHIPO_0001394 a rdfs:Class ;
rdfs:label "resistance to trifloxystrobin" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to trifloxystrobin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0043039 a rdfs:Class ;
rdfs:label "tRNA aminoacylation" ;
rdfs:comment "The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules." ;
rdfs:subClassOf obo:GO_0006399 , obo:GO_0043038 .
obo:GO_0002724 a rdfs:Class ;
rdfs:label "regulation of T cell cytokine production" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of T cell cytokine production." ;
rdfs:subClassOf obo:GO_0002709 , obo:GO_0002718 , obo:GO_0065007 .
obo:CHEBI_63534 a rdfs:Class .
obo:GO_0014064 a rdfs:Class ;
rdfs:label "positive regulation of serotonin secretion" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin." ;
rdfs:subClassOf obo:GO_0014062 , obo:GO_0043270 , obo:GO_0065007 , obo:GO_1903532 .
obo:GO_0042613 a rdfs:Class ;
rdfs:label "MHC class II protein complex" ;
rdfs:comment "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen." ;
rdfs:subClassOf obo:GO_0042611 .
obo:GO_0002444 a rdfs:Class ;
rdfs:label "myeloid leukocyte mediated immunity" ;
rdfs:comment "Any process involved in the carrying out of an immune response by a myeloid leukocyte." ;
rdfs:subClassOf obo:GO_0002376 , obo:GO_0002443 .
obo:CL_4307047 a rdfs:Class ;
rdfs:label "Astro-TE NN_3 Crym astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Crym (Mmus), Grin2c (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Crym, Gabbr2. These cells are located in the Striatum dorsal region, Striatum ventral region , in or close to the regions: Nucleus accumbens, Caudoputamen . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5227 Astro-TE NN_3." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301593 .
obo:GO_0098644 a rdfs:Class ;
rdfs:label "complex of collagen trimers" ;
rdfs:comment "A complex of collagen trimers such as a fibril or collagen network." ;
rdfs:subClassOf obo:GO_0099080 .
obo:PHIPO_0001282 a rdfs:Class ;
rdfs:label "absence of host protein phosphorylation with pathogen"@en ;
rdfs:comment "A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, does not occur during pathogen infection (GO:0006468 protein phosphorylation)." ;
rdfs:subClassOf obo:PHIPO_0001247 .
obo:UBERON_0001638 a rdfs:Class ;
rdfs:label "vein" ;
rdfs:comment "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." ;
rdfs:subClassOf obo:UBERON_0003920 .
obo:PHIPO_0000054 a rdfs:Class ;
rdfs:label "premature asexual sporulation"@en ;
rdfs:comment "A reproductive phenotype in which the occurrence of asexual spore formation happens sooner than normal." ;
rdfs:subClassOf obo:PHIPO_0000078 .
obo:GO_0048087 a rdfs:Class ;
rdfs:label "positive regulation of developmental pigmentation" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ;
rdfs:subClassOf obo:GO_0048070 , obo:GO_0048518 , obo:GO_0065007 .
obo:CHEBI_87211 a rdfs:Class ;
rdfs:label "fluoroquinolone antibiotic" ;
rdfs:comment "An organonitrogen heterocyclic antibiotic containing a quinolone (or quinolone-like) moiety and which have a fluorine atom attached to the central ring system." ;
rdfs:subClassOf obo:CHEBI_25558 , obo:CHEBI_37143 .
obo:GO_1905074 a rdfs:Class ;
rdfs:label "negative regulation of tight junction disassembly" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1905073 .
obo:GO_0030903 a rdfs:Class ;
rdfs:label "notochord development" ;
rdfs:comment "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." ;
rdfs:subClassOf obo:GO_0048568 , obo:GO_0048856 .
obo:GO_0042078 a rdfs:Class ;
rdfs:label "germ-line stem cell division" ;
rdfs:comment "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." ;
rdfs:subClassOf obo:GO_0017145 , obo:GO_0051301 .
obo:GO_1902495 a rdfs:Class ;
rdfs:label "transmembrane transporter complex" ;
rdfs:comment "A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0032991 , obo:GO_0098796 , obo:GO_1990351 .
obo:PHIPO_0000766 a rdfs:Class ;
rdfs:label "sensitive to pentamidine"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to pentamidine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:IAO_0000027 a rdfs:Class ;
rdfs:label "data entity"@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:GO_0002282 a rdfs:Class ;
rdfs:label "microglial cell activation involved in immune response" ;
rdfs:comment "The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." ;
rdfs:subClassOf obo:GO_0001774 , obo:GO_0002281 .
obo:UBERON_0035237 a rdfs:Class ;
rdfs:label "branch of internal carotid artery" ;
rdfs:subClassOf obo:UBERON_0005396 .
obo:GO_1901503 a rdfs:Class ;
rdfs:label "ether biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of ether." ;
rdfs:subClassOf obo:GO_0009058 .
obo:UBERON_0005153 a rdfs:Class ;
rdfs:label "epithelial bud" ;
rdfs:comment "A bud is a protrusion that forms from an epithelial sheet by localized folding." ;
rdfs:subClassOf obo:UBERON_0005157 .
obo:PHIPO_0000983 a rdfs:Class ;
rdfs:label "abnormal meiotic cell cycle"@en ;
rdfs:comment "A reproductive process phenotype in which a cell does not proceed normally through a meiotic cell cycle (GO:0051321)." ;
rdfs:subClassOf obo:PHIPO_0000048 , obo:PHIPO_0000929 .
obo:GO_0007147 a rdfs:Class ;
rdfs:label "female meiosis II" ;
rdfs:comment "The cell cycle process in which the second meiotic division occurs in the female germline." ;
rdfs:subClassOf obo:GO_0007135 , obo:GO_0007143 .
obo:UBERON_0009015 a rdfs:Class ;
rdfs:label "upper back skin" ;
rdfs:comment "A zone of skin that is part of a dorsal thoracic segment of trunk." ;
rdfs:subClassOf obo:UBERON_0000014 , obo:UBERON_0001068 , obo:UBERON_0001418 .
obo:PHIPO_0001036 a rdfs:Class ;
rdfs:label "increased level of substance in cell"@en ;
rdfs:comment "A single species cell phenotype in which the amount of a specific substance measured in a cell is higher than normal." ;
rdfs:subClassOf obo:PHIPO_0000944 .
obo:GO_1903328 a rdfs:Class ;
rdfs:label "positive regulation of tRNA metabolic process" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of tRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051254 , obo:GO_0065007 , obo:GO_1903326 .
obo:GO_0010468 a rdfs:Class ;
rdfs:label "regulation of gene expression" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ;
rdfs:subClassOf obo:GO_0010556 , obo:GO_0065007 .
obo:CHEBI_64047 a rdfs:Class ;
rdfs:label "food additive" ;
rdfs:comment "Any substance which is added to food to preserve or enhance its flavour and/or appearance." ;
rdfs:subClassOf obo:CHEBI_747325 , obo:CHEBI_78295 .
obo:GO_0033241 a rdfs:Class ;
rdfs:label "regulation of amine catabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ;
rdfs:subClassOf obo:GO_0009894 , obo:GO_0033238 , obo:GO_0065007 .
obo:GO_1903296 a rdfs:Class ;
rdfs:label "positive regulation of glutamate secretion, neurotransmission" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter." ;
rdfs:subClassOf obo:GO_0001956 , obo:GO_0014049 , obo:GO_0051968 , obo:GO_0065007 , obo:GO_1903294 .
obo:CL_0000782 a rdfs:Class ;
rdfs:label "myeloid dendritic cell" ;
rdfs:comment "A dendritic cell of the myeloid lineage." ;
rdfs:subClassOf obo:CL_0000766 , obo:CL_0000990 .
obo:GO_0014855 a rdfs:Class ;
rdfs:label "striated muscle cell proliferation" ;
rdfs:comment "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." ;
rdfs:subClassOf obo:GO_0008283 , obo:GO_0033002 .
obo:UBERON_0034709 a rdfs:Class ;
rdfs:label "hindbrain marginal layer" ;
rdfs:subClassOf obo:UBERON_0004062 , obo:UBERON_0011215 .
obo:GO_0051261 a rdfs:Class ;
rdfs:label "protein depolymerization" ;
rdfs:comment "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." ;
rdfs:subClassOf obo:GO_0032984 .
obo:PHIPO_0001155 a rdfs:Class ;
rdfs:label "decreased level of pathogen reactive oxygen species production within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen produced reactive oxygen species (ROS) usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001197 .
obo:GO_1905881 a rdfs:Class ;
rdfs:label "positive regulation of oogenesis" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of oogenesis." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1905879 , obo:GO_2000243 .
obo:PR_P55099 a rdfs:Class ;
rdfs:label "tachykinin-3 (mouse)" ;
rdfs:comment "A tachykinin-3 that is encoded in the genome of mouse." ;
rdfs:subClassOf obo:PR_000016004 , obo:PR_000029032 .
obo:PHIPO_0000771 a rdfs:Class ;
rdfs:label "sensitive to ampicillin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to ampicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000815 .
obo:CHEBI_64909 a rdfs:Class ;
rdfs:label "poison" ;
rdfs:comment "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHEBI_87228 a rdfs:Class ;
rdfs:label "sulfonamide antibiotic" ;
rdfs:comment "A class of sulfonamides whose members generally have bacteriostatic antibiotic properties." ;
rdfs:subClassOf obo:CHEBI_35358 .
obo:UBERON_0002085 a rdfs:Class ;
rdfs:label "interatrial septum" ;
rdfs:comment "A cardiac septum that divides the left and right atria of the heart." ;
rdfs:subClassOf obo:UBERON_0002099 .
obo:CHEBI_22507 a rdfs:Class ;
rdfs:label "aminoglycoside antibiotic" ;
rdfs:subClassOf obo:CHEBI_23007 , obo:CHEBI_47779 .
obo:PHIPO_0000185 a rdfs:Class ;
rdfs:label "obsolete abnormal pathogen host interaction multiple protein binding to DNA" ;
rdfs:comment "A pathogen host interaction (molecular function??) phenotype in which the binding of two or more proteins to DNA is abnormal. The proteins may bind simultaneously or sequentially, but both or all would normally be present together on DNA at some time. One affected gene product may be encoded by the mutated gene, or all may be encoded by different genes." .
obo:UBERON_0010092 a rdfs:Class ;
rdfs:label "future metencephalon" ;
rdfs:comment "A developing anatomical structure that has the potential to develop into a metencephalon." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_0032101 a rdfs:Class ;
rdfs:label "regulation of response to external stimulus" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a response to an external stimulus." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 .
obo:UBERON_0002119 a rdfs:Class ;
rdfs:label "left ovary" ;
rdfs:comment "An ovary that is part of a left side of organism [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000992 , obo:UBERON_0015212 .
obo:GO_1900925 a rdfs:Class ;
rdfs:label "positive regulation of glycine import across plasma membrane" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of glycine import." ;
rdfs:subClassOf obo:GO_0032892 , obo:GO_0034764 , obo:GO_0051957 , obo:GO_0065007 , obo:GO_1900923 .
obo:GO_0001677 a rdfs:Class ;
rdfs:label "formation of translation initiation ternary complex" ;
rdfs:comment "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0022618 .
obo:UBERON_0034710 a rdfs:Class ;
rdfs:label "spinal cord ventricular layer" ;
rdfs:subClassOf obo:UBERON_0004060 .
obo:CL_1001582 a rdfs:Class ;
rdfs:label "lateral ventricle neuron" ;
rdfs:comment "Neuron of lateral ventricle." ;
rdfs:subClassOf obo:CL_0000540 , obo:CL_0012001 .
obo:CL_4310104 a rdfs:Class ;
rdfs:label "OT D1 ICj Islands of Calleja granule cell (Primate)" ;
rdfs:comment "A Islands of Calleja granule cell of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OT D1 ICj." ;
rdfs:subClassOf obo:CL_4030053 .
obo:GO_0016746 a rdfs:Class ;
rdfs:label "acyltransferase activity" ;
rdfs:comment "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor)." ;
rdfs:subClassOf obo:GO_0016740 .
obo:GO_0001841 a rdfs:Class ;
rdfs:label "neural tube formation" ;
rdfs:comment "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." ;
rdfs:subClassOf obo:GO_0001838 , obo:GO_0048646 .
obo:GO_0098545 a rdfs:Class ;
rdfs:label "maintenance of protein complex location in cytoplasm" ;
rdfs:comment "Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0051651 , obo:GO_0098544 .
obo:GO_0071624 a rdfs:Class ;
rdfs:label "positive regulation of granulocyte chemotaxis" ;
rdfs:comment "Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus." ;
rdfs:subClassOf obo:GO_0002690 , obo:GO_0065007 , obo:GO_0071622 .
obo:UBERON_0010052 a rdfs:Class ;
rdfs:label "mucosa of dorsum of tongue" ;
rdfs:comment "A mucosa that is part of a dorsum of tongue." ;
rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0005020 .
obo:GO_0060284 a rdfs:Class ;
rdfs:label "regulation of cell development" ;
rdfs:comment "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ;
rdfs:subClassOf obo:GO_0045595 , obo:GO_0065007 .
obo:UBERON_0004293 a rdfs:Class ;
rdfs:label "parasympathetic nerve" ;
rdfs:comment "A nerve that is part of a parasympathetic nervous system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001021 .
obo:GO_0035107 a rdfs:Class ;
rdfs:label "appendage morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." ;
rdfs:subClassOf obo:GO_0009653 .
obo:CHEBI_60783 a rdfs:Class ;
rdfs:label "nucleoside analogue" ;
rdfs:comment "An analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells." ;
rdfs:subClassOf obo:CHEBI_21731 .
obo:CHEBI_36360 a rdfs:Class ;
rdfs:label "phosphorus oxoacids and derivatives" ;
rdfs:subClassOf obo:CHEBI_26082 .
obo:PHIPO_0000309 a rdfs:Class ;
rdfs:label "obsolete normal effector of pathogenicity suppression of host defense" ;
rdfs:comment "The host defenses suppressed by the pathogen are unaltered compared to the wild type interaction" .
a rdfs:Class ;
rdfs:label "Subcommissural organ" ;
rdfs:subClassOf , obo:UBERON_0002139 .
obo:GO_0002581 a rdfs:Class ;
rdfs:label "negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." ;
rdfs:subClassOf obo:GO_0002578 , obo:GO_0002580 , obo:GO_0065007 .
obo:UBERON_0004849 a rdfs:Class ;
rdfs:label "respiratory system venous endothelium" ;
rdfs:comment "An endothelium of vein that is part of a respiratory system [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001919 , obo:UBERON_0004702 .
obo:GO_0170055 a rdfs:Class ;
rdfs:label "lipid transmembrane transporter activity" ;
rdfs:comment "Enables the transfer of a lipid from one side of a membrane to the other." ;
rdfs:subClassOf obo:GO_0022857 .
obo:PHIPO_0000383 a rdfs:Class ;
rdfs:label "resistance to carbendazim"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to carbendazim. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:UBERON_0002407 a rdfs:Class ;
rdfs:label "pericardium" ;
rdfs:comment "The combination of pericardial sac (a double-walled sac containing the heart and the roots of the great vessels) plus fibrous pericardium." ;
rdfs:subClassOf obo:UBERON_0000481 .
obo:UBERON_0004088 a rdfs:Class ;
rdfs:label "orbital region" ;
rdfs:comment "The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present." ;
rdfs:subClassOf obo:UBERON_0001444 .
obo:CHEBI_24654 a rdfs:Class ;
rdfs:label "hydroxy fatty acid" ;
rdfs:comment "Any fatty acid carrying one or more hydroxy substituents." ;
rdfs:subClassOf obo:CHEBI_35366 , obo:CHEBI_35868 .
obo:PHIPO_0001435 a rdfs:Class ;
rdfs:label "normal growth on cyprodinil" ;
rdfs:comment "A growth phenotype which describes the absence of change of individuals or populations after exposure to cyprodinil (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001308 .
obo:GO_0097427 a rdfs:Class ;
rdfs:label "microtubule bundle" ;
rdfs:comment "An arrangement of closely apposed microtubules running parallel to each other." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0002831 a rdfs:Class ;
rdfs:label "regulation of response to biotic stimulus" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." ;
rdfs:subClassOf obo:GO_0048583 , obo:GO_0065007 .
obo:CHEBI_76861 a rdfs:Class ;
rdfs:label "EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor" ;
rdfs:comment "An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*)." ;
rdfs:subClassOf obo:CHEBI_76730 .
obo:GO_0002607 a rdfs:Class ;
rdfs:label "regulation of myeloid dendritic cell antigen processing and presentation" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation." ;
rdfs:subClassOf obo:GO_0002604 , obo:GO_0065007 .
obo:UBERON_0001969 a rdfs:Class ;
rdfs:label "blood plasma" ;
rdfs:comment "The liquid component of blood, in which erythrocytes are suspended." ;
rdfs:subClassOf obo:UBERON_0000179 , obo:UBERON_0000463 .
obo:GO_0006066 a rdfs:Class ;
rdfs:label "alcohol metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." ;
rdfs:subClassOf obo:GO_0044281 .
obo:GO_0009593 a rdfs:Class ;
rdfs:label "detection of chemical stimulus" ;
rdfs:comment "The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0051606 .
obo:GO_2000979 a rdfs:Class ;
rdfs:label "positive regulation of forebrain neuron differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation." ;
rdfs:subClassOf obo:GO_0045666 , obo:GO_0065007 , obo:GO_2000977 .
obo:UBERON_0003561 a rdfs:Class ;
rdfs:label "forebrain dura mater" ;
rdfs:comment "A dura mater that is part of a forebrain." ;
rdfs:subClassOf obo:UBERON_0002092 , obo:UBERON_0002363 , obo:UBERON_0003548 .
obo:CL_0000850 a rdfs:Class ;
rdfs:label "serotonergic neuron" ;
rdfs:comment "A neuron that releases serotonin as a neurotransmitter." ;
rdfs:subClassOf obo:CL_0000458 , obo:CL_0000540 .
obo:CHEBI_38186 a rdfs:Class ;
rdfs:label "isonicotinate" ;
rdfs:comment "A pyridinemonocarboxylate resulting from the deprotonation of the carboxy group of isonicotinic acid." ;
rdfs:subClassOf obo:CHEBI_38181 .
obo:CHEBI_87113 a rdfs:Class ;
rdfs:label "antibiotic antifungal drug" ;
rdfs:comment "Any antibiotic antifungal agent used to treat fungal infections in humans or animals." ;
rdfs:subClassOf obo:CHEBI_86478 .
obo:CHEBI_34994 a rdfs:Class ;
rdfs:label "teicoplanin A2" ;
rdfs:comment "Any of the glycopeptides whose structure consists of teicoplanin A3-1 in which the hydroxy group of the di(aryloxy)-substituted phenol moiety has been converted to the corresponding 2-acylamino-2-deoxy-β-D-glucoside. Members of the class differ only in the nature of the acyl group." ;
rdfs:subClassOf obo:CHEBI_22160 , obo:CHEBI_24396 , obo:CHEBI_26195 , obo:CHEBI_35618 , obo:CHEBI_51026 , obo:CHEBI_83403 .
obo:PHIPO_0001316 a rdfs:Class ;
rdfs:label "resistance to cymoxanil"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to cymoxanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_2000145 a rdfs:Class ;
rdfs:label "regulation of cell motility" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell motility." ;
rdfs:subClassOf obo:GO_0040012 , obo:GO_0050794 , obo:GO_0065007 .
obo:UBERON_0029005 a rdfs:Class ;
rdfs:label "striosomal part of putamen" ;
rdfs:subClassOf obo:UBERON_0027371 .
obo:CHEBI_38773 a rdfs:Class ;
rdfs:label "quinolinemonocarboxylate" ;
rdfs:comment "A monocarboxylic acid anion that is the monoanion obtained by the deprotonation of the carboxy group attached to the quinoline skeleton" ;
rdfs:subClassOf obo:CHEBI_35757 .
obo:GO_0060581 a rdfs:Class ;
rdfs:label "cell fate commitment involved in pattern specification" ;
rdfs:comment "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type." ;
rdfs:subClassOf obo:GO_0045165 .
obo:GO_0007293 a rdfs:Class ;
rdfs:label "germarium-derived egg chamber formation" ;
rdfs:comment "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0003006 , obo:GO_0048646 .
obo:GO_0002504 a rdfs:Class ;
rdfs:label "antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ;
rdfs:comment "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex." ;
rdfs:subClassOf obo:GO_0019882 .
obo:UBERON_0003825 a rdfs:Class ;
rdfs:label "nerve of abdominal segment" ;
rdfs:comment "A nerve that is part of an abdominal segment of trunk [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001021 , obo:UBERON_0003439 .
obo:PHIPO_0001194 a rdfs:Class ;
rdfs:label "inhibition of pathogen chorismate mutase by host absent"@en ;
rdfs:comment "A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen chorismate mutase is absent." ;
rdfs:subClassOf obo:PHIPO_0000347 .
obo:GO_0021575 a rdfs:Class ;
rdfs:label "hindbrain morphogenesis" ;
rdfs:comment "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." ;
rdfs:subClassOf obo:GO_0009653 .
obo:GO_0061076 a rdfs:Class ;
rdfs:label "negative regulation of neural retina development" ;
rdfs:comment "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." ;
rdfs:subClassOf obo:GO_0061074 , obo:GO_0065007 , obo:GO_1902867 .
obo:GO_0036484 a rdfs:Class ;
rdfs:label "trunk neural crest cell migration" ;
rdfs:comment "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo." ;
rdfs:subClassOf obo:GO_0001755 , obo:GO_0016477 .
obo:UBERON_0004816 a rdfs:Class ;
rdfs:label "larynx epithelium" ;
rdfs:comment "An epithelium that is part of a larynx [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004802 .
obo:UBERON_0007282 a rdfs:Class ;
rdfs:label "presumptive segmental plate" ;
rdfs:comment "A presumptive structure that has the potential to develop into a presomitic mesoderm." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_0021701 a rdfs:Class ;
rdfs:label "cerebellar Golgi cell differentiation" ;
rdfs:comment "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." ;
rdfs:subClassOf obo:GO_0021533 , obo:GO_0021953 , obo:GO_0030154 , obo:GO_0097154 .
obo:UBERON_0007278 a rdfs:Class ;
rdfs:label "presumptive sinus venosus" ;
rdfs:comment "Portion of tissue that is part of the heart tube and will become the sinus venosus." ;
rdfs:subClassOf obo:UBERON_0006598 .
obo:GO_0050773 a rdfs:Class ;
rdfs:label "regulation of dendrite development" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of dendrite development." ;
rdfs:subClassOf obo:GO_0010975 , obo:GO_0050793 , obo:GO_0065007 .
obo:GO_0006033 a rdfs:Class ;
rdfs:label "chitin localization" ;
rdfs:comment "A process in which chitin is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0033037 .
obo:CHEBI_65069 a rdfs:Class ;
rdfs:label "2-deoxystreptamine(2+)" ;
rdfs:comment "An organic cation obtained by protonation of the two free amino groups of 2-deoxystreptamine; major species at pH 7.3." ;
rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 .
obo:PHIPO_0001153 a rdfs:Class ;
rdfs:label "hyphal hyper branching"@en ;
rdfs:comment "A single species cell morphology phenotype in which fungal hyphae form an increased number of branches." ;
rdfs:subClassOf obo:PHIPO_0001427 .
obo:GO_0001666 a rdfs:Class ;
rdfs:label "response to hypoxia" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." ;
rdfs:subClassOf obo:GO_0006950 , obo:GO_0036293 .
obo:GO_0051589 a rdfs:Class ;
rdfs:label "negative regulation of neurotransmitter transport" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0051051 , obo:GO_0051588 , obo:GO_0065007 .
obo:GO_0001837 a rdfs:Class ;
rdfs:label "epithelial to mesenchymal transition" ;
rdfs:comment "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." ;
rdfs:subClassOf obo:GO_0030154 , obo:GO_0048762 .
obo:PHIPO_0000315 a rdfs:Class ;
rdfs:label "obsolete abnormal effector of virulence activation of host defense" ;
rdfs:comment "The pathogen has the ability to cause infectious disease dependent upon the gene for gene relationship between the pathogen and host genotype and this is altered compared to the wildtype interaction. This may result in disease (virulence) or no disease (avirulence)." .
obo:CHEBI_65023 a rdfs:Class ;
rdfs:label "anti-asthmatic agent" ;
rdfs:comment "Any compound that has anti-asthmatic effects." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:UBERON_0005966 a rdfs:Class ;
rdfs:label "outflow part of left atrium" ;
rdfs:comment "An outflow tract of atrium that is part of a left atrium." ;
rdfs:subClassOf obo:UBERON_0005946 .
obo:CHEBI_146295 a rdfs:Class ;
rdfs:label "pyranobenzodioxin" ;
rdfs:comment "Any organic heterotricyclic compound whose core skeleton consists of a benzodioxin ring that is ortho-fused to a pyran ring." ;
rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38104 .
obo:UBERON_0000012 a rdfs:Class ;
rdfs:label "somatic nervous system" ;
rdfs:comment "Part of peripheral nervous system that includes the somatic parts of the cranial and spinal nerves and their ganglia and the peripheral sensory receptors." ;
rdfs:subClassOf obo:UBERON_0011216 .
obo:GO_0048848 a rdfs:Class ;
rdfs:label "neurohypophysis morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0022612 .
obo:GO_0042436 a rdfs:Class ;
rdfs:label "indole-containing compound catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0042430 .
obo:GO_0060124 a rdfs:Class ;
rdfs:label "positive regulation of growth hormone secretion" ;
rdfs:comment "Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell." ;
rdfs:subClassOf obo:GO_0060123 , obo:GO_0065007 , obo:GO_0090277 .
obo:CHEBI_33676 a rdfs:Class ;
rdfs:label "d-block molecular entity" ;
rdfs:comment "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element." ;
rdfs:subClassOf obo:CHEBI_33497 .
obo:CL_0000339 a rdfs:Class ;
rdfs:label "glioblast (sensu Vertebrata)" ;
rdfs:comment "An early neural cell developing from the early ependymal cell of the neural tube." ;
rdfs:subClassOf obo:CL_0000030 , obo:CL_0000123 .
obo:PHIPO_0001115 a rdfs:Class ;
rdfs:label "decreased phosphopantetheinyl transferase activity"@en ;
rdfs:comment "A single species molecular function phenotype in which the observed rate of phosphopantetheinyl transferase activity is decreased." ;
rdfs:subClassOf obo:PHIPO_0000436 .
obo:GO_0090299 a rdfs:Class ;
rdfs:label "regulation of neural crest formation" ;
rdfs:comment "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." ;
rdfs:subClassOf obo:GO_0010717 , obo:GO_0022603 , obo:GO_0065007 .
obo:UBERON_0005564 a rdfs:Class ;
rdfs:label "gonad primordium" ;
rdfs:comment "Portion of tissue that gives rise to the immature gonad." ;
rdfs:subClassOf obo:UBERON_0001048 .
obo:GO_1905154 a rdfs:Class ;
rdfs:label "negative regulation of membrane invagination" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination." ;
rdfs:subClassOf obo:GO_0051129 , obo:GO_0065007 , obo:GO_1905153 .
obo:PR_000001289 a rdfs:Class ;
rdfs:label "membrane-spanning 4-domains subfamily A member 1" ;
rdfs:comment "A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof." ;
rdfs:subClassOf obo:CHEBI_36080 , obo:PR_000000001 .
obo:CL_0000559 a rdfs:Class ;
rdfs:label "promonocyte" ;
rdfs:comment "A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules." ;
rdfs:subClassOf obo:CL_0000763 , obo:CL_0002194 .
obo:GO_0030917 a rdfs:Class ;
rdfs:label "midbrain-hindbrain boundary development" ;
rdfs:comment "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages." ;
rdfs:subClassOf obo:GO_0048856 .
obo:GO_0021694 a rdfs:Class ;
rdfs:label "cerebellar Purkinje cell layer formation" ;
rdfs:comment "The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." ;
rdfs:subClassOf obo:GO_0048646 .
obo:GO_0009626 a rdfs:Class ;
rdfs:label "plant-type hypersensitive response" ;
rdfs:comment "The rapid, localized death of plant cells in response to invasion by a pathogen." ;
rdfs:subClassOf obo:GO_0033554 , obo:GO_0034050 , obo:GO_0045087 .
obo:GO_0010646 a rdfs:Class ;
rdfs:label "regulation of cell communication" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:PHIPO_0000121 a rdfs:Class ;
rdfs:label "abnormal asexual reproductive structure development"@en ;
rdfs:comment "A single species phenotype where the asexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is abnormal (GO:0048608)." ;
rdfs:subClassOf obo:PHIPO_0000043 .
obo:CL_4310115 a rdfs:Class ;
rdfs:label "SN SOX6 Dopa substantia nigra dopaminergic neuron (Primate)" ;
rdfs:comment "A substantia nigra dopaminergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN SOX6 Dopa." ;
rdfs:subClassOf obo:CL_4042025 .
obo:GO_0010664 a rdfs:Class ;
rdfs:label "negative regulation of striated muscle cell apoptotic process" ;
rdfs:comment "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." ;
rdfs:subClassOf obo:GO_0010656 , obo:GO_0010662 , obo:GO_0065007 .
obo:GO_0046649 a rdfs:Class ;
rdfs:label "lymphocyte activation" ;
rdfs:comment "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor." ;
rdfs:subClassOf obo:GO_0001775 , obo:GO_0045321 .
obo:GO_1905293 a rdfs:Class ;
rdfs:label "negative regulation of neural crest cell differentiation" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation." ;
rdfs:subClassOf obo:GO_0051241 , obo:GO_0065007 , obo:GO_1905292 , obo:GO_2000737 .
obo:GO_0120224 a rdfs:Class ;
rdfs:label "larynx development" ;
rdfs:comment "The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." ;
rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 .
obo:CL_0011019 a rdfs:Class ;
rdfs:label "mesothelial cell of epicardium" ;
rdfs:comment "A mesothelial cell that is part of the epicardium." ;
rdfs:subClassOf obo:CL_0000077 , obo:CL_0002494 .
obo:GO_1905063 a rdfs:Class ;
rdfs:label "regulation of vascular associated smooth muscle cell differentiation" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation." ;
rdfs:subClassOf obo:GO_0051150 , obo:GO_0065007 .
obo:CHEBI_48360 a rdfs:Class ;
rdfs:label "amphiprotic solvent" ;
rdfs:comment "Self-ionizing solvent possessing both characteristics of Brønsted acids and bases." ;
rdfs:subClassOf obo:CHEBI_48356 , obo:CHEBI_48359 .
obo:GO_0097435 a rdfs:Class ;
rdfs:label "supramolecular fiber organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." ;
rdfs:subClassOf obo:GO_0016043 .
obo:CL_2000004 a rdfs:Class ;
rdfs:label "pituitary gland cell" ;
rdfs:comment "Any cell that is part of a pituitary gland." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_0002319 .
obo:GO_0021590 a rdfs:Class ;
rdfs:label "cerebellum maturation" ;
rdfs:comment "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills." ;
rdfs:subClassOf obo:GO_0021700 , obo:GO_0071695 .
obo:UBERON_0001916 a rdfs:Class ;
rdfs:label "endothelium of arteriole" ;
rdfs:comment "An endothelium that is part of an arteriole [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0001986 , obo:UBERON_0004700 , obo:UBERON_0008339 .
obo:GO_1990497 a rdfs:Class ;
rdfs:label "regulation of cytoplasmic translation in response to stress" ;
rdfs:comment "Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
rdfs:subClassOf obo:GO_0043555 , obo:GO_0065007 , obo:GO_2000765 .
obo:PATO_0045084 a rdfs:Class ;
rdfs:label "normal duration" ;
rdfs:comment "A duration quality of a process which is relatively normal." ;
rdfs:subClassOf obo:PATO_0001309 , obo:PATO_0045073 .
obo:UBERON_0009663 a rdfs:Class ;
rdfs:label "telencephalic nucleus" ;
rdfs:comment "A nucleus of brain that is part of a telencephalon." ;
rdfs:subClassOf obo:UBERON_0002308 .
obo:CHEBI_79093 a rdfs:Class ;
rdfs:label "EC 1.11.2.2 (myeloperoxidase) inhibitor" ;
rdfs:comment "An EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor that interferes with the action of myeloperoxidase (EC 1.11.2.2)." ;
rdfs:subClassOf obo:CHEBI_79092 .
obo:PHIPO_0000021 a rdfs:Class ;
rdfs:label "increased sensitivity to chemical" ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to a specific chemical. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0001218 .
obo:GO_0045581 a rdfs:Class ;
rdfs:label "negative regulation of T cell differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation." ;
rdfs:subClassOf obo:GO_0045580 , obo:GO_0045620 , obo:GO_0050868 , obo:GO_0065007 .
obo:GO_1990778 a rdfs:Class ;
rdfs:label "protein localization to cell periphery" ;
rdfs:comment "A process in which a protein is transported to, or maintained in, the cell periphery." ;
rdfs:subClassOf obo:GO_0008104 .
obo:UBERON_0004906 a rdfs:Class ;
rdfs:label "ectodermal part of digestive tract" ;
rdfs:comment "A portion of the gut that is derived from ectoderm." ;
rdfs:subClassOf obo:UBERON_0004121 , obo:UBERON_0004921 .
obo:CHEBI_26208 a rdfs:Class ;
rdfs:label "polyunsaturated fatty acid" ;
rdfs:comment "Any fatty acid containing more than one double bond. Acids in this group are reported to have cardioprotective effects; and levels are lowered in chronic fatigue syndrome." ;
rdfs:subClassOf obo:CHEBI_27208 .
obo:UBERON_0005389 a rdfs:Class ;
rdfs:label "transparent eye structure" ;
rdfs:comment "A transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:GO_0010636 a rdfs:Class ;
rdfs:label "positive regulation of mitochondrial fusion" ;
rdfs:comment "Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment." ;
rdfs:subClassOf obo:GO_0010635 , obo:GO_0010638 , obo:GO_0051094 , obo:GO_0065007 .
obo:GO_0048743 a rdfs:Class ;
rdfs:label "positive regulation of skeletal muscle fiber development" ;
rdfs:comment "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." ;
rdfs:subClassOf obo:GO_0010720 , obo:GO_0048643 , obo:GO_0048742 , obo:GO_0051155 , obo:GO_0065007 .
obo:CHEBI_35175 a rdfs:Class ;
rdfs:label "sulfate salt" ;
rdfs:subClassOf obo:CHEBI_24866 , obo:CHEBI_26820 .
obo:CHEBI_35780 a rdfs:Class ;
rdfs:label "phosphate ion" ;
rdfs:comment "A phosphorus oxoanion that is the conjugate base of phosphoric acid." ;
rdfs:subClassOf obo:CHEBI_33461 .
obo:NCBITaxon_32524 a rdfs:Class ;
rdfs:label "Amniota" ;
rdfs:subClassOf obo:NCBITaxon_32523 .
obo:CHEBI_29259 a rdfs:Class ;
rdfs:label "hydrogenphosphite" ;
rdfs:comment "A divalent inorganic anion resulting from the removal of a proton from two of the hydroxy groups of phosphorous acid." ;
rdfs:subClassOf obo:CHEBI_26045 , obo:CHEBI_79388 .
obo:UBERON_0007635 a rdfs:Class ;
rdfs:label "nucleus of medulla oblongata" ;
rdfs:comment "A neural nucleus that is part of a medulla oblongata." ;
rdfs:subClassOf obo:UBERON_0000125 , obo:UBERON_0006331 , obo:UBERON_0009662 .
obo:PHIPO_0000757 a rdfs:Class ;
rdfs:label "sensitive to fenhexamid"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenhexamid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:UBERON_0000179 a rdfs:Class ;
rdfs:label "haemolymphatic fluid" ;
rdfs:comment "Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs." ;
rdfs:subClassOf obo:UBERON_0000463 , obo:UBERON_0006314 .
obo:CHEBI_46848 a rdfs:Class ;
rdfs:label "N-arylpiperazine" ;
rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_33860 , obo:CHEBI_50996 .
obo:PATO_0001374 a rdfs:Class ;
rdfs:label "ploidy" ;
rdfs:comment "A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism." ;
rdfs:subClassOf obo:PATO_0001396 .
obo:CL_0000666 a rdfs:Class ;
rdfs:label "fenestrated endothelial cell" ;
rdfs:comment "An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues." ;
rdfs:subClassOf obo:CL_0000115 .
obo:GO_0002820 a rdfs:Class ;
rdfs:label "negative regulation of adaptive immune response" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response." ;
rdfs:subClassOf obo:GO_0002819 , obo:GO_0050777 , obo:GO_0065007 .
obo:GO_0090300 a rdfs:Class ;
rdfs:label "positive regulation of neural crest formation" ;
rdfs:comment "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." ;
rdfs:subClassOf obo:GO_0010718 , obo:GO_0065007 , obo:GO_0090299 .
obo:GO_0033504 a rdfs:Class ;
rdfs:label "floor plate development" ;
rdfs:comment "The progression of the floor plate over time from its initial formation until its mature state." ;
rdfs:subClassOf obo:GO_0048856 .
obo:UBERON_0007692 a rdfs:Class ;
rdfs:label "nucleus of thalamus" ;
rdfs:comment "A nucleus of brain that is part of a thalamus." ;
rdfs:subClassOf obo:UBERON_0002308 , obo:UBERON_0006569 .
obo:CHEBI_28866 a rdfs:Class ;
rdfs:label "tetracosanoic acid" ;
rdfs:comment "A C24 straight-chain saturated fatty acid." ;
rdfs:subClassOf obo:CHEBI_27283 , obo:CHEBI_39418 .
obo:UBERON_0001881 a rdfs:Class ;
rdfs:label "island of Calleja" ;
rdfs:comment "One of the seven small groups of granule cells in the polymorph layer of the olfactory tubercle and one large group, the insula magna, which lies along the border between septum, nucleus accumbens and nucleus of the diagonal band." ;
rdfs:subClassOf obo:UBERON_0009663 .
obo:UBERON_0001768 a rdfs:Class ;
rdfs:label "uvea" ;
rdfs:comment "The pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]." ;
rdfs:subClassOf obo:UBERON_0004923 , obo:UBERON_0010314 .
obo:UBERON_0003563 a rdfs:Class ;
rdfs:label "telencephalon dura mater" ;
rdfs:comment "A dura mater that is part of a telencephalon [Automatically generated definition]." ;
rdfs:subClassOf obo:UBERON_0002363 , obo:UBERON_0003289 , obo:UBERON_0003561 .
obo:GO_0048601 a rdfs:Class ;
rdfs:label "oocyte morphogenesis" ;
rdfs:comment "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte." ;
rdfs:subClassOf obo:GO_0000902 , obo:GO_0003006 , obo:GO_0009653 .
obo:UBERON_0004365 a rdfs:Class ;
rdfs:label "vitelline blood vessel" ;
rdfs:comment "Blood vessel that is connected to the yolk sac." ;
rdfs:subClassOf obo:UBERON_0001981 .
obo:GO_0032892 a rdfs:Class ;
rdfs:label "positive regulation of organic acid transport" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ;
rdfs:subClassOf obo:GO_0032890 , obo:GO_0051050 , obo:GO_0065007 .
obo:UBERON_0002435 a rdfs:Class ;
rdfs:label "striatum" ;
rdfs:comment "A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.[GO]." ;
rdfs:subClassOf obo:UBERON_0011300 .
obo:UBERON_0004185 a rdfs:Class ;
rdfs:label "endodermal part of digestive tract" ;
rdfs:comment "A portions of the gut that is derived from endoderm." ;
rdfs:subClassOf obo:UBERON_0004119 , obo:UBERON_0004921 .
obo:GO_0045786 a rdfs:Class ;
rdfs:label "negative regulation of cell cycle" ;
rdfs:comment "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." ;
rdfs:subClassOf obo:GO_0048523 , obo:GO_0051726 , obo:GO_0065007 .
obo:GO_0043177 a rdfs:Class ;
rdfs:label "organic acid binding" ;
rdfs:comment "Binding to an organic acid, any acidic compound containing carbon in covalent linkage." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0036094 .
obo:UBERON_0000065 a rdfs:Class ;
rdfs:label "respiratory tract" ;
rdfs:comment "Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts." ;
rdfs:subClassOf obo:UBERON_0001005 .
obo:UBERON_0014621 a rdfs:Class ;
rdfs:label "cervical spinal cord ventral horn" ;
rdfs:comment "A ventral horn of spinal cord that is part of a cervical spinal cord." ;
rdfs:subClassOf obo:UBERON_0002257 .
obo:GO_1905294 a rdfs:Class ;
rdfs:label "positive regulation of neural crest cell differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation." ;
rdfs:subClassOf obo:GO_0051240 , obo:GO_0065007 , obo:GO_1905292 , obo:GO_2000738 .
obo:UBERON_0000062 a rdfs:Class ;
rdfs:label "organ" ;
rdfs:comment "Anatomical structure that performs a specific function or group of functions [WP]." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:UBERON_0019267 a rdfs:Class ;
rdfs:label "gray matter of midbrain" ;
rdfs:subClassOf obo:UBERON_0002020 , obo:UBERON_0003528 .
obo:GO_0042173 a rdfs:Class ;
rdfs:label "regulation of sporulation resulting in formation of a cellular spore" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of spore formation." ;
rdfs:subClassOf obo:GO_0043937 , obo:GO_0065007 .
obo:PHIPO_0000995 a rdfs:Class ;
rdfs:label "decreased level of pathogen RNA within host"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the level of pathogen RNA usually present during infection is lower than normal." ;
rdfs:subClassOf obo:PHIPO_0001267 .
obo:PHIPO_0000501 a rdfs:Class ;
rdfs:label "obsolete increased level of deoxynivalenol" ;
rdfs:comment "A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is higher than normal." .
obo:CL_2000073 a rdfs:Class ;
rdfs:label "migratory cardiac neural crest cell" ;
rdfs:comment "Any migratory neural crest cell that is part of a cardiac neural crest." ;
rdfs:subClassOf obo:CL_0000333 .
obo:GO_0048339 a rdfs:Class ;
rdfs:label "paraxial mesoderm development" ;
rdfs:comment "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube." ;
rdfs:subClassOf obo:GO_0007498 , obo:GO_0048856 , obo:GO_0060485 .
obo:GO_0051684 a rdfs:Class ;
rdfs:label "maintenance of Golgi location" ;
rdfs:comment "Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere." ;
rdfs:subClassOf obo:GO_0051645 , obo:GO_0051651 , obo:GO_0051657 .
obo:GO_1904179 a rdfs:Class ;
rdfs:label "positive regulation of adipose tissue development" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of adipose tissue development." ;
rdfs:subClassOf obo:GO_0051094 , obo:GO_0051240 , obo:GO_0065007 , obo:GO_1904177 .
obo:CL_1000479 a rdfs:Class ;
rdfs:label "Purkinje myocyte of atrioventricular node" ;
rdfs:comment "A Purkinje myocyte that is part of the atrioventricular node." ;
rdfs:subClassOf obo:CL_0002068 , obo:CL_1000410 .
obo:GO_0001745 a rdfs:Class ;
rdfs:label "compound eye morphogenesis" ;
rdfs:comment "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster." ;
rdfs:subClassOf obo:GO_0009653 , obo:GO_0048592 .
obo:GO_0071697 a rdfs:Class ;
rdfs:label "ectodermal placode morphogenesis" ;
rdfs:comment "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." ;
rdfs:subClassOf obo:GO_0009653 .
obo:PHIPO_0000903 a rdfs:Class ;
rdfs:label "sensitive to nikkomycin Z"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to nikkomycin Z. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:CHEBI_24867 a rdfs:Class ;
rdfs:label "monoatomic ion" ;
rdfs:subClassOf obo:CHEBI_24870 , obo:CHEBI_33238 .
obo:PHIPO_0000274 a rdfs:Class ;
rdfs:label "increased asexual spore germination frequency" ;
rdfs:comment "A population phenotype in which the frequency of occurrence of asexual spore germination is increased." ;
rdfs:subClassOf obo:PHIPO_0000509 , obo:PHIPO_0000929 .
obo:PHIPO_0000639 a rdfs:Class ;
rdfs:label "resistance to quinupristin-dalfopristin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to quinupristin-dalfopristin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:PHIPO_0001430 a rdfs:Class ;
rdfs:label "resistance to ipconazole" ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to ipconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0045216 a rdfs:Class ;
rdfs:label "cell-cell junction organization" ;
rdfs:comment "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells." ;
rdfs:subClassOf obo:GO_0034330 .
obo:GO_0019778 a rdfs:Class ;
rdfs:label "Atg12 activating enzyme activity" ;
rdfs:comment "Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond." ;
rdfs:subClassOf obo:GO_0008641 .
obo:PHIPO_0001126 a rdfs:Class ;
rdfs:label "decreased growth on palmitic acid carbon source"@en ;
rdfs:comment "A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing palmitic acid as the carbon source." ;
rdfs:subClassOf obo:PHIPO_0001216 .
obo:CL_4307034 a rdfs:Class ;
rdfs:label "Astro-NT NN_2 Fzd2 astrocyte (Mmus)" ;
rdfs:comment "A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Sfrp5 (Mmus), Gria2 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Fzd2, Gria2, Ttll3. These cells are located in the Midbrain, Thalamus, Pons , in or close to the regions: Midbrain reticular nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5214 Astro-NT NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301590 .
obo:GO_1901162 a rdfs:Class ;
rdfs:label "primary amino compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of primary amino compound." ;
rdfs:subClassOf obo:GO_0009058 .
obo:PHIPO_0001253 a rdfs:Class ;
rdfs:label "host immune system inflammatory response activated by pathogen present"@en ;
rdfs:comment "A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection is present. (GO:0006954 inflammatory response)." ;
rdfs:subClassOf obo:PHIPO_0001167 .
obo:CHEBI_83986 a rdfs:Class ;
rdfs:label "ethylenebis(dithiocarbamic acid)" ;
rdfs:comment "A dithiocarbamic acid resulting from the formal addition of a molecule of carbon disulfide to each amino group of ethylenediamine." ;
rdfs:subClassOf obo:CHEBI_78787 .
obo:CHEBI_48589 a rdfs:Class ;
rdfs:label "piperidones" ;
rdfs:subClassOf obo:CHEBI_26151 , obo:CHEBI_36963 .
obo:PHIPO_0001256 a rdfs:Class ;
rdfs:label "host defense-related protein involved in a pathogen interaction present"@en ;
rdfs:comment "A pathogen host interaction phenotype, in which the host defense-related protein usually present during infection is normal (i.e. indistinguishable from wild type)." ;
rdfs:subClassOf obo:PHIPO_0001251 .
obo:GO_0002181 a rdfs:Class ;
rdfs:label "cytoplasmic translation" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein." ;
rdfs:subClassOf obo:GO_0006412 .
obo:GO_0009314 a rdfs:Class ;
rdfs:label "response to radiation" ;
rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." ;
rdfs:subClassOf obo:GO_0009628 .
obo:GO_0046189 a rdfs:Class ;
rdfs:label "phenol-containing compound biosynthetic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ;
rdfs:subClassOf obo:GO_0009058 , obo:GO_0018958 .
obo:PHIPO_0001075 a rdfs:Class ;
rdfs:label "auxotrophic growth"@en ;
rdfs:comment "A growth phenotype which describes an individual or a population of organisms which requires a particular organic compound, which is not required by a wild-type for its growth. Auxotrophy usually results from a cell's inability to synthesize the compound." ;
rdfs:subClassOf obo:PHIPO_0001216 .
obo:CHEBI_52646 a rdfs:Class ;
rdfs:label "leptomycin B" ;
rdfs:comment "A leptomycin having a (2E,10E,12E,16Z,18E)-double bond configuration as well as an ethyl substituent at position 17." ;
rdfs:subClassOf obo:CHEBI_140345 , obo:CHEBI_52651 .
obo:GO_0042447 a rdfs:Class ;
rdfs:label "hormone catabolic process" ;
rdfs:comment "The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." ;
rdfs:subClassOf obo:GO_0009056 , obo:GO_0042445 .
obo:PHIPO_0000883 a rdfs:Class ;
rdfs:label "sensitive to levofloxacin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to levofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_0045656 a rdfs:Class ;
rdfs:label "negative regulation of monocyte differentiation" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation." ;
rdfs:subClassOf obo:GO_0002762 , obo:GO_0045655 , obo:GO_0065007 .
obo:CL_0000152 a rdfs:Class ;
rdfs:label "exocrine cell" ;
rdfs:comment "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct." ;
rdfs:subClassOf obo:CL_0000151 , obo:CL_0000255 .
obo:UBERON_0003077 a rdfs:Class ;
rdfs:label "paraxial mesoderm" ;
rdfs:comment "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]." ;
rdfs:subClassOf obo:UBERON_0005291 , obo:UBERON_0007524 , obo:UBERON_0015212 .
obo:PHIPO_0001441 a rdfs:Class ;
rdfs:label "abnormal mycotoxin biosythesis"@en ;
rdfs:comment "A single organism phenotype in which an abnormal amount of mycotoxin is produced." ;
rdfs:subClassOf obo:PHIPO_0001442 .
obo:UBERON_0007844 a rdfs:Class ;
rdfs:label "cartilage element" ;
rdfs:comment "Skeletal element that is composed of cartilage tissue and may be permanent or transient." ;
rdfs:subClassOf obo:UBERON_0004765 .
obo:GO_0010927 a rdfs:Class ;
rdfs:label "cellular component assembly involved in morphogenesis" ;
rdfs:comment "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." ;
rdfs:subClassOf obo:GO_0022607 , obo:GO_0048646 .
obo:UBERON_0004146 a rdfs:Class ;
rdfs:label "His-Purkinje system" ;
rdfs:comment "The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." ;
rdfs:subClassOf obo:UBERON_0010131 , obo:UBERON_0018649 .
obo:PHIPO_0000949 a rdfs:Class ;
rdfs:label "pathogen entry into host phenotype"@en ;
rdfs:comment "A pathogen colonization of host phenotype which affects the penetration of the pathogen into the body, tissues, or cells of the host organism (GO:0044409)." ;
rdfs:subClassOf obo:PHIPO_0000332 .
obo:GO_0032886 a rdfs:Class ;
rdfs:label "regulation of microtubule-based process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." ;
rdfs:subClassOf obo:GO_0050794 , obo:GO_0065007 .
obo:CL_0000838 a rdfs:Class ;
rdfs:label "lymphoid lineage restricted progenitor cell" ;
rdfs:comment "A progenitor cell restricted to the lymphoid lineage." ;
rdfs:subClassOf obo:CL_0002031 , obo:CL_0011026 .
obo:CHEBI_25903 a rdfs:Class ;
rdfs:label "peptide antibiotic" ;
rdfs:comment "A chemically diverse class of peptides that exhibit antimicrobial properties." ;
rdfs:subClassOf obo:CHEBI_16670 .
obo:GO_0030887 a rdfs:Class ;
rdfs:label "positive regulation of myeloid dendritic cell activation" ;
rdfs:comment "Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation." ;
rdfs:subClassOf obo:GO_0002696 , obo:GO_0030885 , obo:GO_0065007 .
obo:CHEBI_38337 a rdfs:Class ;
rdfs:label "pyrimidone" ;
rdfs:comment "A pyrimidine carrying one or more oxo substituents." ;
rdfs:subClassOf obo:CHEBI_39447 .
obo:PHIPO_0000972 a rdfs:Class ;
rdfs:label "abolished protein localization to autophagosome"@en ;
rdfs:comment "A single organism phenotype in which a protein does not localize to, and is therefore absent from the autophagosome (GO:0005776)." ;
rdfs:subClassOf obo:PHIPO_0000245 , obo:PHIPO_0000973 .
obo:GO_0050908 a rdfs:Class ;
rdfs:label "detection of light stimulus involved in visual perception" ;
rdfs:comment "The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal." ;
rdfs:subClassOf obo:GO_0009583 , obo:GO_0050962 .
obo:GO_0030097 a rdfs:Class ;
rdfs:label "hemopoiesis" ;
rdfs:comment "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." ;
rdfs:subClassOf obo:GO_0032502 , obo:GO_0048468 .
obo:PHIPO_0000816 a rdfs:Class ;
rdfs:label "sensitive to prothionamide"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to prothionamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:GO_1902107 a rdfs:Class ;
rdfs:label "positive regulation of leukocyte differentiation" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of leukocyte differentiation." ;
rdfs:subClassOf obo:GO_0065007 , obo:GO_1902105 , obo:GO_1903708 .
obo:GO_0010625 a rdfs:Class ;
rdfs:label "positive regulation of Schwann cell proliferation" ;
rdfs:comment "Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." ;
rdfs:subClassOf obo:GO_0010624 , obo:GO_0060252 , obo:GO_0065007 .
obo:CHEBI_474053 a rdfs:Class ;
rdfs:label "cefazolin" ;
rdfs:comment "A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively." ;
rdfs:subClassOf obo:CHEBI_23066 , obo:CHEBI_35689 , obo:CHEBI_38099 , obo:CHEBI_88225 .
obo:CHEBI_35554 a rdfs:Class ;
rdfs:label "cardiovascular drug" ;
rdfs:comment "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." ;
rdfs:subClassOf obo:CHEBI_23888 .
obo:GO_0051241 a rdfs:Class ;
rdfs:label "negative regulation of multicellular organismal process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ;
rdfs:subClassOf obo:GO_0048519 , obo:GO_0051239 , obo:GO_0065007 .
obo:CHEBI_25248 a rdfs:Class ;
rdfs:label "methyl ester" ;
rdfs:comment "Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol." ;
rdfs:subClassOf obo:CHEBI_33308 .
obo:PHIPO_0000853 a rdfs:Class ;
rdfs:label "sensitive to capreomycin"@en ;
rdfs:comment "A growth phenotype which describes the sensitivity of individuals or populations after exposure to capreomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000021 .
obo:PHIPO_0000105 a rdfs:Class ;
rdfs:label "decreased size of penetration structure"@en ;
rdfs:comment "A single species pathogen growth phenotype in which the size of pathogen penetration stuctures are decreased when assessed for penetration ability on a given experimental substance/membrane." ;
rdfs:subClassOf obo:PHIPO_0000032 .
obo:GO_0008017 a rdfs:Class ;
rdfs:label "microtubule binding" ;
rdfs:comment "Binding to a microtubule, a filament composed of tubulin monomers." ;
rdfs:subClassOf obo:GO_0005488 , obo:GO_0015631 .
obo:GO_0051641 a rdfs:Class ;
rdfs:label "cellular localization" ;
rdfs:comment "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0051179 .
obo:PHIPO_0000679 a rdfs:Class ;
rdfs:label "resistance to tebuconazole"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to tebuconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:GO_0002682 a rdfs:Class ;
rdfs:label "regulation of immune system process" ;
rdfs:comment "Any process that modulates the frequency, rate, or extent of an immune system process." ;
rdfs:subClassOf obo:GO_0050789 , obo:GO_0065007 .
obo:PHIPO_0000664 a rdfs:Class ;
rdfs:label "resistance to spiroxamine"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to spiroxamine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CHEBI_33304 a rdfs:Class ;
rdfs:label "chalcogen molecular entity" ;
rdfs:comment "Any p-block molecular entity containing a chalcogen." ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:GO_0032056 a rdfs:Class ;
rdfs:label "positive regulation of translation in response to stress" ;
rdfs:comment "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress." ;
rdfs:subClassOf obo:GO_0043555 , obo:GO_0045727 , obo:GO_0065007 .
obo:CHEBI_77318 a rdfs:Class ;
rdfs:label "pregnane X receptor agonist" ;
rdfs:comment "An agonist that selectively binds to and activates a pregnane X receptor." ;
rdfs:subClassOf obo:CHEBI_48705 .
obo:PHIPO_0000411 a rdfs:Class ;
rdfs:label "molecular function phenotype"@en ;
rdfs:comment "A phenotype that affects a molecular function such as binding or catalytic activity." ;
rdfs:subClassOf obo:PHIPO_0000002 .
obo:GO_1900366 a rdfs:Class ;
rdfs:label "negative regulation of defense response to insect" ;
rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect." ;
rdfs:subClassOf obo:GO_0002832 , obo:GO_0031348 , obo:GO_0032102 , obo:GO_0065007 , obo:GO_2000068 .
obo:PHIPO_0000601 a rdfs:Class ;
rdfs:label "resistance to amikacin"@en ;
rdfs:comment "A growth phenotype which describes the resistance of individuals or populations after exposure to amikacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow." ;
rdfs:subClassOf obo:PHIPO_0000022 .
obo:CL_4307099 a rdfs:Class ;
rdfs:label "NFOL NN_2 Dbx2 newly formed oligodendrocyte (Mmus)" ;
rdfs:comment "A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Dbx2 (Mmus), Rassf10 (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Dbx2, Rassf10. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5279 NFOL NN_2." ;
rdfs:subClassOf obo:CL_0000000 , obo:CL_4301612 .
obo:CL_0017503 a rdfs:Class ;
rdfs:label "basophilic cytoplasm" ;
rdfs:comment "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions." ;
rdfs:subClassOf obo:GO_0005737 .
obo:CL_0000024 a rdfs:Class ;
rdfs:label "oogonial cell" ;
rdfs:comment "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." ;
rdfs:subClassOf obo:CL_0000021 .
obo:UBERON_0002424 a rdfs:Class ;
rdfs:label "oral epithelium" ;
rdfs:comment "An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues." ;
rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0003350 , obo:UBERON_0003929 .
obo:CHEBI_55374 a rdfs:Class ;
rdfs:label "oxazolidinone" ;
rdfs:comment "An oxazolidine containing one or more oxo groups." ;
rdfs:subClassOf obo:CHEBI_38329 .
obo:GO_0007585 a rdfs:Class ;
rdfs:label "respiratory gaseous exchange by respiratory system" ;
rdfs:comment "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." ;
rdfs:subClassOf obo:GO_0032501 .
obo:BSPO_0000097 a rdf:Property ;
rdfs:range .
obo:BSPO_0000100 a rdf:Property ;
rdfs:range .
obo:IAO_0000115 a rdf:Property ;
rdfs:label "textual definition" ;
rdfs:comment "The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
rdfs:range xsd:string .
obo:IAO_0100001 a rdf:Property ;
rdfs:label "term replaced by" ;
rdfs:comment "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
rdfs:range xsd:string .
obo:IDO_0000660 a rdf:Property ;
rdfs:label "results_in"@en ;
rdfs:range .
obo:PHIPO_0000304 a rdf:Property ;
rdfs:label "qualifier"@en ;
rdfs:comment "Used in FYPO as described in PATO best practices; placeholder relation to indicate normality/abnormality. which namespace? do we need all 3 triplicated again?" ;
rdfs:range .
obo:RO_0000080 a rdf:Property ;
rdfs:label "quality of"@en ;
rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:RO_0000081 a rdf:Property ;
rdfs:label "role of"@en ;
rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:RO_0000092 a rdf:Property ;
rdfs:label "disposition of"@en ;
rdfs:comment "inverse of has disposition" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:RO_0002000 a rdf:Property ;
rdfs:label "2D boundary of"@en ;
rdfs:comment "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002323 .
obo:RO_0002006 a rdf:Property ;
rdfs:label "has synaptic terminal of"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0002013 a rdf:Property ;
rdfs:label "has regulatory component activity" ;
rdfs:comment "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 , obo:RO_0002017 .
obo:RO_0002014 a rdf:Property ;
rdfs:label "has negative regulatory component activity" ;
rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002335 , obo:RO_0002013 .
obo:RO_0002015 a rdf:Property ;
rdfs:label "has positive regulatory component activity" ;
rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002336 , obo:RO_0002013 .
obo:RO_0002017 a rdf:Property ;
rdfs:label "has component activity" ;
rdfs:comment "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002018 .
obo:RO_0002021 a rdf:Property ;
rdfs:label "occurs across" ;
rdfs:comment "A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002479 .
obo:RO_0002022 a rdf:Property ;
rdfs:label "directly regulated by" ;
rdfs:comment "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 .
obo:RO_0002023 a rdf:Property ;
rdfs:label "directly negatively regulated by" ;
rdfs:comment "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002022 .
obo:RO_0002024 a rdf:Property ;
rdfs:label "directly positively regulated by" ;
rdfs:comment "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002022 .
obo:RO_0002025 a rdf:Property ;
rdfs:label "has effector activity" ;
rdfs:comment "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002017 .
obo:RO_0002081 a rdf:Property ;
rdfs:label "before or simultaneous with"@en ;
rdfs:comment "Primitive instance level timing relation between events" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002222 .
obo:RO_0002086 a rdf:Property ;
rdfs:label "ends after"@en ;
rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002222 .
obo:RO_0002090 a rdf:Property ;
rdfs:label "immediately precedes"@en ;
rdfs:comment "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:BFO_0000063 .
obo:RO_0002163 a rdf:Property ;
rdfs:label "spatially disjoint from" ;
rdfs:comment "A is spatially_disjoint_from B if and only if they have no parts in common" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002323 .
obo:RO_0002178 a rdf:Property ;
rdfs:label "supplies"@en ;
rdfs:comment "Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002170 .
obo:RO_0002179 a rdf:Property ;
rdfs:label "drains"@en ;
rdfs:comment "Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002170 .
obo:RO_0002210 a rdf:Property ;
rdfs:label "directly develops into"@en ;
rdfs:comment "inverse of directly develops from" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002203 .
obo:RO_0002234 a rdf:Property ;
rdfs:label "has output"@en ;
rdfs:comment "p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000057 .
obo:RO_0002253 a rdf:Property ;
rdfs:label "has connecting branch" ;
rdfs:comment "inverse of connecting branch of" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002375 .
obo:RO_0002255 a rdf:Property ;
rdfs:label "developmentally contributes to"@en ;
rdfs:comment "inverse of has developmental contribution from" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002385 , obo:RO_0002286 .
obo:RO_0002257 a rdf:Property ;
rdfs:label "developmentally induces"@en ;
rdfs:comment "Inverse of developmentally induced by"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002386 , obo:RO_0002286 .
obo:RO_0002259 a rdf:Property ;
rdfs:range xsd:string .
obo:RO_0002263 a rdf:Property ;
rdfs:label "acts upstream of" ;
rdfs:comment "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002264 .
obo:RO_0002264 a rdf:Property ;
rdfs:label "acts upstream of or within" ;
rdfs:comment "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002500 .
obo:RO_0002286 a rdf:Property ;
rdfs:label "developmentally succeeded by"@en ;
rdfs:comment "Inverse of developmentally preceded by" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002384 .
obo:RO_0002287 a rdf:Property ;
rdfs:label "part of developmental precursor of"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002286 .
obo:RO_0002304 a rdf:Property ;
rdfs:label "causally upstream of, positive effect" ;
rdfs:comment "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004047 , obo:RO_0002411 .
obo:RO_0002305 a rdf:Property ;
rdfs:label "causally upstream of, negative effect" ;
rdfs:comment "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004046 , obo:RO_0002411 .
obo:RO_0002314 a rdf:Property ;
rdfs:label "characteristic of part of"@en ;
rdfs:comment "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002502 .
obo:RO_0002320 a rdf:Property ;
rdfs:label "evolutionarily related to"@en ;
rdfs:comment "A relationship that holds via some environmental process" ;
rdfs:range .
obo:RO_0002323 a rdf:Property ;
rdfs:label "mereotopologically related to"@en ;
rdfs:comment "A mereological relationship or a topological relationship" ;
rdfs:range .
obo:RO_0002324 a rdf:Property ;
rdfs:label "developmentally related to"@en ;
rdfs:comment "A relationship that holds between entities participating in some developmental process (GO:0032502)" ;
rdfs:range .
obo:RO_0002327 a rdf:Property ;
rdfs:label "enables"@en ;
rdfs:comment "c enables p iff c is capable of p and c acts to execute p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002215 .
obo:RO_0002329 a rdf:Property ;
rdfs:label "part of structure that is capable of"@en ;
rdfs:comment "this relation holds between c and p when c is part of some c', and c' is capable of p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 .
obo:RO_0002331 a rdf:Property ;
rdfs:label "involved in"@en ;
rdfs:comment "c involved_in p if and only if c enables some process p', and p' is part of p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0000056 .
obo:RO_0002333 a rdf:Property ;
rdfs:label "enabled by"@en ;
rdfs:comment "inverse of enables" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000057 .
obo:RO_0002335 a rdf:Property ;
rdfs:label "negatively regulated by"@en ;
rdfs:comment "inverse of negatively regulates" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 .
obo:RO_0002336 a rdf:Property ;
rdfs:label "positively regulated by"@en ;
rdfs:comment "inverse of positively regulates" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 .
obo:RO_0002350 a rdf:Property ;
rdfs:label "member of"@en ;
rdfs:comment "is member of is a mereological relation between a item and a collection." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:BFO_0000050 .
obo:RO_0002352 a rdf:Property ;
rdfs:label "input of"@en ;
rdfs:comment "inverse of has input" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .
obo:RO_0002354 a rdf:Property ;
rdfs:label "formed as result of"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002353 .
obo:RO_0002379 a rdf:Property ;
rdfs:label "spatially coextensive with"@en ;
rdfs:comment "x spatially_coextensive_with y if and inly if x and y have the same location" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0002386 a rdf:Property ;
rdfs:label "has potential to developmentally induce"@en ;
rdfs:comment "x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002384 .
obo:RO_0002388 a rdf:Property ;
rdfs:label "has potential to directly develop into"@en ;
rdfs:comment "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002387 .
obo:RO_0002404 a rdf:Property ;
rdfs:label "causally downstream of"@en ;
rdfs:comment "inverse of upstream of" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002427 , obo:BFO_0000062 .
obo:RO_0002405 a rdf:Property ;
rdfs:label "immediately causally downstream of"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002404 , obo:RO_0002087 .
obo:RO_0002407 a rdf:Property ;
rdfs:label "indirectly positively regulates"@en ;
rdfs:comment "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002213 .
obo:RO_0002409 a rdf:Property ;
rdfs:label "indirectly negatively regulates"@en ;
rdfs:comment "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002212 .
obo:RO_0002410 a rdf:Property ;
rdfs:label "causally related to"@en ;
rdfs:comment "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." ;
rdfs:range .
obo:RO_0002411 a rdf:Property ;
rdfs:label "causally upstream of"@en ;
rdfs:comment "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000063 .
obo:RO_0002412 a rdf:Property ;
rdfs:label "immediately causally upstream of"@en ;
rdfs:comment "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002411 , obo:RO_0002090 .
obo:RO_0002413 a rdf:Property ;
rdfs:label "provides input for"@en ;
rdfs:comment "p provides input for q iff p is immediately causally upstream of q, and there exists some c such that p has_output c and q has_input c." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002414 , obo:RO_0002412 .
obo:RO_0002418 a rdf:Property ;
rdfs:label "causally upstream of or within" ;
rdfs:comment "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002501 .
obo:RO_0002427 a rdf:Property ;
rdfs:label "causally downstream of or within" ;
rdfs:comment "inverse of causally upstream of or within" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002501 .
obo:RO_0002428 a rdf:Property ;
rdfs:label "involved in regulation of" ;
rdfs:comment "c involved in regulation of p if c is involved in some p' and p' regulates some p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0002263 .
obo:RO_0002429 a rdf:Property ;
rdfs:label "involved in positive regulation of" ;
rdfs:comment "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002428 .
obo:RO_0002430 a rdf:Property ;
rdfs:label "involved in negative regulation of" ;
rdfs:comment "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002428 .
obo:RO_0002431 a rdf:Property ;
rdfs:label "involved in or involved in regulation of" ;
rdfs:comment "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0002500 , obo:RO_0002264 .
obo:RO_0002432 a rdf:Property ;
rdfs:label "is active in" ;
rdfs:comment "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0002131 .
obo:RO_0002436 a rdf:Property ;
rdfs:label "molecularly interacts with" ;
rdfs:comment "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002434 .
obo:RO_0002447 a rdf:Property ;
rdfs:label "phosphorylates" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002436 .
obo:RO_0002464 a rdf:Property ;
rdfs:label "helper property (not for use in curation)" ;
rdfs:range .
obo:RO_0002481 a rdf:Property ;
rdfs:label "is kinase activity" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002564 .
obo:RO_0002485 a rdf:Property ;
rdfs:label "receives input from" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002170 .
obo:RO_0002486 a rdf:Property ;
rdfs:label "sends output to" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002170 .
obo:RO_0002490 a rdf:Property ;
rdfs:label "existence overlaps" ;
rdfs:comment "x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002487 .
obo:RO_0002500 a rdf:Property ;
rdfs:label "causal agent in process" ;
rdfs:comment "A relationship between a material entity and a process where the material entity has some causal role that influences the process" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002595 .
obo:RO_0002502 a rdf:Property ;
rdfs:label "depends on" ;
rdfs:range .
obo:RO_0002503 a rdf:Property ;
rdfs:label "towards" ;
rdfs:comment "q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002502 .
obo:RO_0002559 a rdf:Property ;
rdfs:label "causally influenced by" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002506 .
obo:RO_0002563 a rdf:Property ;
rdfs:label "interaction relation helper property" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002464 .
obo:RO_0002564 a rdf:Property ;
rdfs:label "molecular interaction relation helper property" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002563 .
obo:RO_0002569 a rdf:Property ;
rdfs:label "has branching part" ;
rdfs:comment "inverse of branching part of" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002375 , obo:BFO_0000051 .
obo:RO_0002571 a rdf:Property ;
rdfs:label "lumen of" ;
rdfs:comment "x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull." ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:BFO_0000050 .
obo:RO_0002578 a rdf:Property ;
rdfs:label "directly regulates" ;
rdfs:comment "p directly regulates q iff p is immediately causally upstream of q and p regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002412 , obo:RO_0002211 .
obo:RO_0002584 a rdf:Property ;
rdfs:label "has part structure that is capable of" ;
rdfs:comment "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002595 , obo:RO_0002328 .
obo:RO_0002586 a rdf:Property ;
rdfs:label "results in breakdown of" ;
rdfs:comment "p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002233 .
obo:RO_0002597 a rdf:Property ;
rdfs:label "capable of negatively regulating" ;
rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002596 .
obo:RO_0002598 a rdf:Property ;
rdfs:label "capable of positively regulating" ;
rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002596 .
obo:RO_0002629 a rdf:Property ;
rdfs:label "directly positively regulates" ;
rdfs:comment "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002213 .
obo:RO_0002630 a rdf:Property ;
rdfs:label "directly negatively regulates" ;
rdfs:comment "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002212 .
obo:RO_0004031 a rdf:Property ;
rdfs:label "enables subfunction" ;
rdfs:comment "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 .
obo:RO_0004032 a rdf:Property ;
rdfs:label "acts upstream of or within, positive effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002264 .
obo:RO_0004033 a rdf:Property ;
rdfs:label "acts upstream of or within, negative effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002264 .
obo:RO_0004034 a rdf:Property ;
rdfs:label "acts upstream of, positive effect" ;
rdfs:comment "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004032 , obo:RO_0002263 .
obo:RO_0004035 a rdf:Property ;
rdfs:label "acts upstream of, negative effect" ;
rdfs:comment "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004033 , obo:RO_0002263 .
obo:RO_0004046 a rdf:Property ;
rdfs:label "causally upstream of or within, negative effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002418 .
obo:RO_0004047 a rdf:Property ;
rdfs:label "causally upstream of or within, positive effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002418 .
obo:RO_0012011 a rdf:Property ;
rdfs:label "indirectly causally upstream of"@en ;
rdfs:comment "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002411 .
obo:RO_0012012 a rdf:Property ;
rdfs:label "indirectly regulates"@en ;
rdfs:comment "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0012011 , obo:RO_0002211 .
obo:RO_0015002 a rdf:Property ;
rdfs:label "exemplar data of" ;
rdfs:range .
obo:RO_0015003 a rdf:Property ;
rdfs:label "subcluster of" ;
rdfs:comment "A relation between a group and another group it is part of but does not fully constitute." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:BFO_0000050 .
obo:RO_0017001 a rdf:Property ;
rdfs:label "device utilizes material"@en ;
rdfs:comment "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." ;
rdfs:range .
obo:RO_0019001 a rdf:Property ;
rdfs:label "positively regulates characteristic" ;
rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0019000 .
obo:RO_0019002 a rdf:Property ;
rdfs:label "negatively regulates characteristic" ;
rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0019000 .
obo:RO_0040036 a rdf:Property ;
rdfs:label "results in changes to anatomical or cellular structure" ;
rdfs:comment "p has anatomical participant c iff p has participant c, and c is an anatomical entity" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000057 .