PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:RO_0000059 a rdf:Property ;
  rdfs:label "concretizes"@en ;
  rdfs:comment "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ;
  rdfs:domain obo:BFO_0000020 ;
  rdfs:range obo:BFO_0000031 .

obo:RO_0000056 a rdf:Property ;
  rdfs:label "participates_in" ;
  rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 .

obo:RO_0002506 a rdf:Property ;
  rdfs:label "causal relation between entities" ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:BFO_0000054 a rdf:Property ;
  rdfs:label "realized in"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000017 ;
  rdfs:range obo:BFO_0000015 .

obo:RO_0002566 a rdf:Property ;
  rdfs:label "causally influences" ;
  rdfs:comment "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0002506 .

obo:RO_0000079 a rdf:Property ;
  rdfs:label "function of"@en ;
  rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000034 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:label "part_of" ;
  rdfs:comment "a core relation that holds between a part and its whole"@en ;
  rdfs:seeAlso <http://www.obofoundry.org/ro/#OBO_REL:part_of> ;
  rdfs:range obo:BFO_0000017 , obo:BFO_0000031 , obo:BFO_0000004 , obo:BFO_0000019 , obo:BFO_0000020 , obo:BFO_0000003 , obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:PDRO_0010039 a rdfs:Class ;
  rdfs:label "state of consciousness condition"@en , "condition indiquant un état de concience"@fr ;
  rdfs:comment "a condition  that is true if and only if an individual is in some specific state of consciousness."@en , "Une condition qui est vraie si et seulement si un individu est dans un certain état de conscience."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:OBI_0001938 a rdf:Property ;
  rdfs:label "has value specification" ;
  rdfs:comment "A relation between an information content entity and a value specification that specifies its value." ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range obo:OBI_0001933 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000136 a rdf:Property ;
  rdfs:label "is about"@en ;
  rdfs:comment "is_about is a (currently) primitive relation that relates an information artifact to an entity."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OMIABIS_0000048 a rdf:Property ;
  rdfs:label "is owned by"@en ;
  rdfs:comment "a is owned by b if b has complete power over a. All rights and obligations of ownership are grounded in this (primitive) relation. The claims and obligations of ownership can be partially transferred to a third party by the owner, b."@en ;
  rdfs:range xsd:string .

obo:RO_0000058 a rdf:Property ;
  rdfs:label "is concretized as"@en ;
  rdfs:comment "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants."@en ;
  rdfs:domain obo:BFO_0000031 ;
  rdfs:range obo:BFO_0000020 .

obo:PDRO_0010022 a rdfs:Class ;
  rdfs:label "drug administration specification"@en , "spécification d’administration de médicament"@fr ;
  rdfs:comment """A drug administration description that specifies a drug administration prescribed or reported by an healthcare provider.

It specifies:
- The drug product
- The posology

It may also specify a starting drug administration condition"""@en , """Une entité informationnelle directive indiquant l'administration d'un médicament.

Elle indique :
- le médicament.
- le(s) condition(s) de distribution du médicament.
- la quantité de médicament à distribuer.
- le(s) condition(s) de début d'administration du médicament.
- le(s) condition(s) de continuation d'administration du médicament
- le(s) condition(s) d'administration d'une dose
- comment administrer une dose, ce qui inclut:
-- Toute préparation du médicament requise avant l'administration.
-- La dose à administrer.
-- Le mode d'administration
-- Toute particularité dans la manière d'administrer le médicament."""@fr ;
  rdfs:subClassOf obo:PDRO_0000323 .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has part" ;
  rdfs:comment "a core relation that holds between a whole and its part"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:PDRO_0010018 a rdfs:Class ;
  rdfs:label "treatment objective specification"@en , "spécification d'objectif de traitement"@fr ;
  rdfs:comment "A health care objective specification that specifies a treatment."@en , "Une spécification d'objectif de santé de traitement."@fr ;
  rdfs:subClassOf obo:PDRO_0010010 .

obo:OBI_0000833 a rdf:Property ;
  rdfs:label "objective_achieved_by" ;
  rdfs:comment "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:domain obo:IAO_0000005 ;
  rdfs:range obo:OBI_0000011 .

obo:OMIABIS_0001025 a rdfs:Class ;
  rdfs:label "survey plan specification"@en ;
  rdfs:comment "A plan specification that is realized by  process of gathering information (e.g. by asking questions)."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:IAO_0000009 a rdfs:Class ;
  rdfs:label "datum label"@en ;
  rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OPMI_0000095 a rdfs:Class ;
  rdfs:label "person first name"@en ;
  rdfs:subClassOf obo:OPMI_0000094 .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity"@en ;
  rdfs:comment "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:UBERON_0000465 a rdfs:Class ;
  rdfs:label "material anatomical entity" ;
  rdfs:comment "Anatomical entity that has mass." ;
  rdfs:subClassOf obo:BFO_0000040 , obo:UBERON_0001062 .

obo:RO_0002450 a rdf:Property ;
  rdfs:label "directly positively regulates activity of" ;
  rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.""" ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002448 .

obo:RO_0002449 a rdf:Property ;
  rdfs:label "directly negatively regulates activity of" ;
  rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.""" ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002448 .

obo:RO_0002448 a rdf:Property ;
  rdfs:label "directly regulates activity of" ;
  rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.

A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.""" ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0011002 , obo:RO_0002436 .

obo:RO_0020105 a rdf:Property ;
  rdfs:label "is anatomical entity" ;
  rdfs:comment "This property only applies to anatomical entities." ;
  rdfs:domain obo:UBERON_0001062 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0011002 a rdf:Property ;
  rdfs:label "regulates activity of" ;
  rdfs:comment "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002566 .

obo:RO_0000087 a rdf:Property ;
  rdfs:label "has role" ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000023 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000085 a rdf:Property ;
  rdfs:label "has function"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000034 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002595 a rdf:Property ;
  rdfs:label "causal relation between material entity and a process" ;
  rdfs:comment "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0000091 a rdf:Property ;
  rdfs:label "has disposition"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000016 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002434 a rdf:Property ;
  rdfs:label "interacts with" ;
  rdfs:comment "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 .

obo:RO_0002215 a rdf:Property ;
  rdfs:label "capable of"@en ;
  rdfs:comment "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002216 .

obo:PDRO_0010032 a rdfs:Class ;
  rdfs:label "substance quantity value specification"@en , "spécification de quantité de substance"@fr ;
  rdfs:comment "A scalar value specification that specifies the quantity of an element or compound with uniform disposition."@en , "Une spécification de valeur scalaire qui spécifie la quantité d'un élément ou d'un composé avec une disposition uniforme."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:OBI_0002135 a rdf:Property ;
  rdfs:label "has specified value"@en ;
  rdfs:comment "A relation between a value specification and a literal." ;
  rdfs:domain obo:OBI_0001933 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0001927 a rdf:Property ;
  rdfs:label "specifies value of" ;
  rdfs:comment "A relation between a value specification and an entity which the specification is about." ;
  rdfs:domain obo:OBI_0001933 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:OBI_0001937 a rdf:Property ;
  rdfs:label "has specified numeric value" ;
  rdfs:comment "A relation between a value specification and a number that quantifies it." ;
  rdfs:domain obo:OBI_0001933 ;
  rdfs:range <http://www.w3.org/2002/07/owl#real> ;
  rdfs:subPropertyOf obo:OBI_0002135 .

obo:IAO_0000039 a rdf:Property ;
  rdfs:label "has measurement unit label"@en ;
  rdfs:range obo:IAO_0000003 , obo:UO_0000002 , obo:UO_0000095 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:PDRO_0000050 a rdfs:Class ;
  rdfs:label "day of the week"@en , "jour de la semaine"@fr ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:BFO_0000145 a rdfs:Class ;
  rdfs:label "relational quality"@en ;
  rdfs:comment "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:PDRO_0010037 a rdfs:Class ;
  rdfs:label "dose administration count specification"@en , "spécification de nombre d'administrations de doses"@fr ;
  rdfs:comment "A scalar value specification that specifies a number of dose administrations."@en , "Une spécification de valeur scalaire qui indique un nombre d'administrations de doses."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:OBI_0001933 a rdfs:Class ;
  rdfs:label "value specification" ;
  rdfs:comment "An information content entity that specifies a value within a classification scheme or on a quantitative scale." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PDRO_0000146 a rdfs:Class ;
  rdfs:label "maximum dosage condition"@en , "condition de dosage maximal"@fr ;
  rdfs:comment "A dosing condition that is true if and only if the amount of drug product administered to a patient has not exceeded a certain amount per unit of time."@en , "Une condition de dosage qui est vraie si et seulement si la quantité de médicament administrée à un patient n’excède pas une certaine quantité par unité de temps."@fr ;
  rdfs:subClassOf obo:PDRO_0000147 .

obo:PDRO_0010030 a rdfs:Class ;
  rdfs:label "dose administration frequency specification"@en , "spécification de fréquence d'administration de dose"@fr ;
  rdfs:comment "A value specification of the frequency of a dose administration."@en , """Une spécification de valeur de fréquence indiquant la fréquence d'un processus d'administration de dose.
Elle a une unité de la forme \"administrations de dose par unité de temps\"."""@fr ;
  rdfs:subClassOf obo:PDRO_0010004 .

obo:PDRO_0000034 a rdfs:Class ;
  rdfs:label "initial rate of administration specification"@en , "spécification de débit initial d'administration de dose"@fr ;
  rdfs:comment "An information content entity that specifies the initial rate at which a dose should be administered."@en , "Une entité de contenu informationnel qui spécifie le taux initial auquel une dose doit être administrée."@fr ;
  rdfs:subClassOf obo:PDRO_0000112 .

obo:PATO_0001405 a rdfs:Class ;
  rdfs:label "anucleate" ;
  rdfs:comment "A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus." ;
  rdfs:subClassOf obo:PATO_0001404 .

obo:PDRO_0000124 a rdfs:Class ;
  rdfs:label "active ingredient quantification specification"@en , "spécification de quantité d’ingrédient actif dans une dose"@fr ;
  rdfs:comment "A dose quantification specification that quantifies a dose by referring to the quantity of active ingredient administered in a dose administration."@en , "Une spécification de quantification de dose spécifiant une quantité d’ingrédient actif à administrer lors d’une administration de dose."@fr ;
  rdfs:subClassOf obo:PDRO_0000123 .

obo:IAO_0000302 a rdfs:Class ;
  rdfs:label "author identification"@en ;
  rdfs:comment "A textual entity intended to identify a particular author"@en ;
  rdfs:subClassOf obo:IAO_0000590 .

obo:PDRO_0010046 a rdfs:Class ;
  rdfs:label "number of dispensings condition"@en , "condition indiquant un nombre de distributions passées"@fr ;
  rdfs:comment "A condition describing the number of dispensings that have occurred as directed by a certain prescription."@en , "Une condition d'une prescription décrivant un nombre de distributions passées."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:COB_0000022 a rdfs:Class ;
  rdfs:label "organism" ;
  rdfs:comment "A material entity that is a maximal functionally integrated unit that develops from a program encoded in a genome" ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:UO_0000006 a rdfs:Class ;
  rdfs:label "substance unit" ;
  rdfs:comment "\"A unit which is a standardised quantity of an element or compound with uniform composition.\" [Wikipedia:Wikipedia]" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:OMRSE_00000024 a rdfs:Class ;
  rdfs:label "role in human social processes"@en ;
  rdfs:comment "A role inhering in an entity realized by social interactions in human society."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:RO_0000052 a rdf:Property ;
  rdfs:label "inheres in"@en ;
  rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
  rdfs:range <https://w3id.org/linkml/Any> , obo:NCBITaxon_9606 , obo:BFO_0000040 , obo:OBI_0000245 ;
  rdfs:subPropertyOf obo:RO_0002314 .

obo:PDRO_0000019 a rdfs:Class ;
  rdfs:label "temporal instant specification"@en , "spécification d'instant temporel"@fr ;
  rdfs:comment "A value specification that specifies a temporal instant."@en , "Une spécification de valeur qui spécifie un instant temporel."@fr ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:BFO_0000030 a rdfs:Class ;
  rdfs:label "object"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:PDRO_0000190 a rdfs:Class ;
  rdfs:label "dose administration specification"@en , "spécification d'administration de dose"@fr ;
  rdfs:comment "An action specification that describes a dose administration."@en , "Une spécification d'action qui décrit une administration de dose médicamenteuse."@fr ;
  rdfs:subClassOf obo:IAO_0000007 .

obo:PDRO_0000053 a rdfs:Class ;
  rdfs:label "drug active ingredient specification"@en , "spécification d’ingrédient actif de médicament"@fr ;
  rdfs:comment "An information content entity that specifies an active ingredient in a drug product."@en , "Une entité de contenu informationnel qui spécifie un ingrédient actif d’un médicament prescrit."@fr ;
  rdfs:subClassOf obo:PDRO_0000009 .

obo:PDRO_0000323 a rdfs:Class ;
  rdfs:label "drug administration description"@en ;
  rdfs:comment "An action specification that describe the administration of a drug, wether it is prescribed or reported by a healthcare provider or self reported by the individual taking said drug."@en ;
  rdfs:subClassOf obo:IAO_0000007 .

obo:BFO_0000182 a rdfs:Class ;
  rdfs:label "history"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:BFO_0000062 a rdf:Property ;
  rdfs:label "preceded by"@en ;
  rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002086 .

obo:BFO_0000063 a rdf:Property ;
  rdfs:label "precedes"@en ;
  rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002501 a rdf:Property ;
  rdfs:label "causal relation between processes" ;
  rdfs:comment "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0019000 a rdf:Property ;
  rdfs:label "regulates characteristic" ;
  rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:PATO_0000001 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0002233 a rdf:Property ;
  rdfs:label "has input"@en ;
  rdfs:comment "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002211 a rdf:Property ;
  rdfs:label "regulates"@en ;
  rdfs:comment "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0002018 a rdf:Property ;
  rdfs:label "has component process" ;
  rdfs:comment "w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002180 .

obo:BFO_0000055 a rdf:Property ;
  rdfs:label "realizes"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000017 .

obo:RO_0000057 a rdf:Property ;
  rdfs:label "has participant"@en ;
  rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 .

obo:RO_0002222 a rdf:Property ;
  rdfs:label "temporally related to"@en ;
  rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 .

obo:RO_0002334 a rdf:Property ;
  rdfs:label "regulated by"@en ;
  rdfs:comment "inverse of regulates" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002427 .

obo:PDRO_0000071 a rdfs:Class ;
  rdfs:label "time elapsed since previous dose condition"@en , "condition indiquant le temps écoulé depuis une précédente administration de dose"@fr ;
  rdfs:comment "a condition describing the time elapsed since the previous dose administration of some drug administration."@en , "une condition de temps écoulé depuis la dernière administration de dose d'une certaine administration de médicament."@fr ;
  rdfs:subClassOf obo:PDRO_0010053 .

obo:PDRO_0000008 a rdfs:Class ;
  rdfs:label "prescribed site of drug administration specification"@en , "spécification de site d’administration de médicament prescrit"@fr ;
  rdfs:comment "A site of drug administration specification that is part of a drug administration specification in a drug prescription."@en , "Une spécification de site d’administration de médicament dans une spécification d'administration de médicament faisant partie d'une prescription de médicament."@fr ;
  rdfs:subClassOf obo:PDRO_0000094 .

obo:PATO_0001018 a rdfs:Class ;
  rdfs:label "physical quality" ;
  rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:PDRO_0000317 a rdfs:Class ;
  rdfs:label "drug prescription validity period specification"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000219 a rdf:Property ;
  rdfs:label "denotes"@en ;
  rdfs:comment "denotes is a primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically"@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:PATO_0000117 a rdfs:Class ;
  rdfs:label "size" ;
  rdfs:comment "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." ;
  rdfs:subClassOf obo:PATO_0000051 .

obo:OMRSE_00000102 a rdfs:Class ;
  rdfs:label "health care facility"@en ;
  rdfs:subClassOf obo:OMRSE_00000062 .

obo:RO_0000053 a rdf:Property ;
  rdfs:label "has characteristic"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000020 .

obo:OMRSE_00000068 a rdf:Property ;
  rdfs:label "is administered by"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000006 a rdfs:Class ;
  rdfs:label "spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:PDRO_0000312 a rdfs:Class ;
  rdfs:label "drug product proprietary label"@en ;
  rdfs:subClassOf obo:PDRO_0000009 .

obo:PDRO_0010053 a rdfs:Class ;
  rdfs:label "time elapsed since dose condition"@en , "condition indiquant le temps écoulé depuis une administration de dose"@fr ;
  rdfs:comment "a condition describing the time elapsed since a dose administration."@en , "Une condition décrivant le temps écoulé depuis une administration de dose."@fr ;
  rdfs:subClassOf obo:PDRO_0010041 .

obo:PDRO_0000060 a rdfs:Class ;
  rdfs:label "drug product specification"@en , "Spécification de produit médicamenteux"@fr ;
  rdfs:comment "An drug product characterization specifying a class of drug product."@en , "Une entité de contenu informationelle qui spécifie une classe de médicament prévu pour être administré."@fr ;
  rdfs:subClassOf obo:PDRO_0000324 .

obo:PATO_0001396 a rdfs:Class ;
  rdfs:label "cellular quality" ;
  rdfs:comment "A monadic quality of continuant that exists at the cellular level of organisation." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:PDRO_0000194 a rdfs:Class ;
  rdfs:label "pharmacist drug dispensing specification"@en ;
  rdfs:comment "A drug dispensing specification that is part of a pharmacist information system and specifies how much of a given drug product has been dispensed to a patient."@en ;
  rdfs:subClassOf obo:PDRO_0000096 .

obo:PDRO_0010019 a rdfs:Class ;
  rdfs:label "prophylaxis objective specification"@en , "spécification d'objectif prophylactique"@fr ;
  rdfs:comment "A health care objective specification that specifies a prophylaxis."@en , "Une spécification d'objectif de santé prophylactique."@fr ;
  rdfs:subClassOf obo:PDRO_0010010 .

obo:UO_0000003 a rdfs:Class ;
  rdfs:label "time unit" ;
  rdfs:comment "\"A unit which is a standard measure of the dimension in which events occur in sequence.\" [Wikipedia:Wikipedia]" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:PDRO_0010042 a rdfs:Class ;
  rdfs:label "number of doses per unit time condition"@en , "condition décrivant le nombre de doses par unité de temps"@fr ;
  rdfs:comment "a condition describing the number of dose administrations that have occurred over a given duration of time."@en , "une condition décrivant le nombre d'administration de doses qui se sont produites pendant une certaine durée de temps."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:OBI_0000576 a rdfs:Class ;
  rdfs:label "scattered molecular aggregate"@en ;
  rdfs:comment "a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000643 a rdf:Property ;
  rdfs:label "has grain" ;
  rdfs:comment "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car." ;
  rdfs:range obo:CHEBI_23367 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:PDRO_0000029 a rdfs:Class ;
  rdfs:label "drug strength per mass unit item"@en , "élément d'information de force médicamenteuse par unité de masse"@fr ;
  rdfs:comment "A drug strength item where the unit quantity is the mass of the drug product."@en , "Un élément d'information de force médicamenteuse où l'unité de quantité de médicament est une unité de masse."@fr ;
  rdfs:subClassOf obo:PDRO_0000026 .

obo:HADO_0000008 a rdfs:Class ;
  rdfs:label "patient"@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:OMIABIS_0000009 a rdf:Property ;
  rdfs:label "administrates"@en ;
  rdfs:comment "a administrates b if c owns b and some rights and obligations grounded in the owning relation regarding b are transferred  from c to a."@en ;
  rdfs:range xsd:string .

obo:OMIABIS_0000008 a rdf:Property ;
  rdfs:label "owns"@en ;
  rdfs:range xsd:string .

obo:PDRO_0000097 a rdfs:Class ;
  rdfs:label "Drug Identification Number"@en , "Numéro d’identification d’un médicament"@fr ;
  rdfs:comment """A Drug Identification Number (DIN) is a computer-generated eight digit number assigned by Health Canada to a drug product prior to being marketed in Canada. It uniquely identifies all drug products sold in a dosage form in Canada and is located on the label of prescription and over-the-counter drug products that have been evaluated and authorized for sale in Canada.

A DIN uniquely identifies the following product characteristics: manufacturer; product name; active ingredient(s); strength(s) of active ingredient(s); pharmaceutical form; route of administration."""@en , """Le numéro d'identification d'une drogue (DIN) est un numéro de huit chiffres généré par un ordinateur qui est attribué par Santé Canada avant d'être commercialisé au Canada. Le DIN est unique et sert a identifier tous les médicaments vendus dans une forme posologique. Il est inscrit sur l'étiquette d'un médicament de prescription ou d'un médicament sans ordonnance qui ont été évalués et approuvés pour la vente au Canada.

Un DIN énumère les caractéristiques du produit: fabricant, nom du produit, ingrédient(s), la force de l'ingrédient médicinal, la forme posologique et la voie d'administration."""@fr ;
  rdfs:subClassOf obo:IAO_0000577 .

obo:PDRO_0000151 a rdfs:Class ;
  rdfs:label "drug dispensing count specification"@en , "spécification de nombre de distributions de médicaments"@fr ;
  rdfs:comment "A scalar value specification that specifies a number of dispensing processes."@en , "Une spécification de valeur scalaire qui indique un nombre de distributions de médicaments."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:PDRO_0000082 a rdfs:Class ;
  rdfs:label "less than some number of doses have occurred condition"@en , "condition de nombre d’administration de doses maximum"@fr ;
  rdfs:comment "A number of doses in drug administration condition  that is true if and only if less than some number of dose administrations have occurred."@en , "Une condition de nombre de doses d’administration de médicament qui est vraie si et seulement si moins d’un certain nombre d’administration de doses ont été effectuées."@fr ;
  rdfs:subClassOf obo:PDRO_0000078 .

obo:PDRO_0010041 a rdfs:Class ;
  rdfs:label "time elapsed condition"@en , "condition de temps écoulé"@fr ;
  rdfs:comment "a condition describing the amount of time that has elapsed since an event."@en , "une condition décrivant le temps écoulé depuis un évènement."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:BFO_0000029 a rdfs:Class ;
  rdfs:label "site"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:PDRO_0000001 a rdfs:Class ;
  rdfs:label "health care prescription"@en , "prescription de santé"@fr ;
  rdfs:comment "A document authored by a health care provider that specifies how to realize some health care process for a particular patient."@en , "Un document créé par un fournisseur de soin indiquant comment réaliser une partie d'un processus de santé pour un patient particulier."@fr ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:HADO_0000004 a rdfs:Class ;
  rdfs:label "health insurance identifier"@en ;
  rdfs:comment "An individual organism identifier that is used to identify a beneficiary of some health insurance."@en ;
  rdfs:subClassOf obo:OBI_0001141 .

obo:PDRO_0000093 a rdfs:Class ;
  rdfs:label "after some surgery condition"@en , "condition de fin de chirurgie"@fr ;
  rdfs:comment "A condition that is true if and only if some surgery has ended."@en , "Une condition qui est vraie si et seulement si une certaine intervention chirurgicale est finie."@fr ;
  rdfs:subClassOf obo:PDRO_0000090 .

obo:PDRO_0000012 a rdfs:Class ;
  rdfs:label "drug treatment"@en , "traitement médicamenteux"@fr ;
  rdfs:comment "A treatment composed of one or more dose administrations."@en , "Un traitement composé d'une ou plusieurs administrations de doses."@fr ;
  rdfs:subClassOf obo:OGMS_0000090 .

obo:OBI_0000417 a rdf:Property ;
  rdfs:label "achieves_planned_objective" ;
  rdfs:comment "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:IAO_0000005 .

obo:OBI_0000293 a rdf:Property ;
  rdfs:label "has_specified_input"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OBI_0000299 a rdf:Property ;
  rdfs:label "has_specified_output"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:PDRO_0000027 a rdfs:Class ;
  rdfs:label "drug strength per discrete dose form item"@en , "élément d'information de force médicamenteuse par forme discrète"@fr ;
  rdfs:comment "A drug strength item where the unit quantity is a discrete solid dose form."@en , "Un élément d'information de force médicamenteuse où l'unité de quantité de médicament est une forme de dose médicamenteuse solide et discrète."@fr ;
  rdfs:subClassOf obo:PDRO_0000026 .

obo:BFO_0000038 a rdfs:Class ;
  rdfs:label "one-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:IAO_0000314 a rdfs:Class ;
  rdfs:label "document part"@en ;
  rdfs:comment "an information content entity that is part of a document"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000684 a rdfs:Class ;
  rdfs:label "specimen collection objective" ;
  rdfs:comment "A objective specification to obtain a material entity for potential use as an input during an investigation." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:PDRO_0010052 a rdfs:Class ;
  rdfs:label "equal to total dosage condition"@en , "condition de dosage total égal à une certaine quantité"@fr ;
  rdfs:comment "A total dosage condition  that is true if and only if the total dosage administered is equal to a specified amount."@en , "une condition de dosage total où le dosage total administré est égal à une certaine quantité."@fr ;
  rdfs:subClassOf obo:PDRO_0010049 .

obo:PDRO_0010004 a rdfs:Class ;
  rdfs:label "frequency value specification"@en , "spécification de valeur de fréquence"@fr ;
  rdfs:comment "A scalar value specification that specifies the frequency of a process."@en , "Une spécification de valeur scalaire indiquant la fréquence d'un processus."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:PDRO_0000120 a rdfs:Class ;
  rdfs:label "excipient aggregate"@en , "aggrégat d'excipient"@fr ;
  rdfs:comment "scattered molecular aggregate with the role of excipient."@en , "Un aggrégat de molécule dispersée ayant le rôle d'excipient."@fr ;
  rdfs:subClassOf obo:OBI_0000576 .

obo:PDRO_0000306 a rdfs:Class ;
  rdfs:label "drug administration cessation condition"@en , "condition d'arrêt d’administration de médicament"@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:PDRO_0010008 a rdfs:Class ;
  rdfs:label "prescribed drug administration"@en , "administration de médicament"@fr ;
  rdfs:comment "A process in which the administration of a drug product as prescribed is hypothesized to achieve some health care objective."@en , "Un processus pendant lequel une ou plusieurs administrations de dose est supposée remplir un certain objectif de santé."@fr ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OPMI_0000102 a rdfs:Class ;
  rdfs:label "maiden name"@en ;
  rdfs:comment "A woman's surname before marriage" ;
  rdfs:subClassOf obo:OPMI_0000096 .

obo:PDRO_0000020 a rdfs:Class ;
  rdfs:label "route of administration specification"@en , "spécification de voie d'administration"@fr ;
  rdfs:comment "An information content entity that specifies the route(s) of administration of a drug product."@en , "Une entité informationnelle indiquant la ou les voies d'administration d'un médicament."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PDRO_9876003 a rdfs:Class ;
  rdfs:label "active ingredient aggregate biological activity"@en , "activité biologique d'un aggrégat d'ingrédient actif"@fr ;
  rdfs:comment "A quality inhering in an active ingredient aggregate by virtue of the magnitude of a standardized biological effect of that active ingredient."@en , "Une qualité inhérent dans un aggrégat d'ingrédient actif en vertu d'une magnitude d'effet biologique standardisé de cet ingrédient actif."@fr ;
  rdfs:subClassOf obo:BFO_0000019 .

<http://www.w3.org/2003/11/swrl#Variable> a rdfs:Class .

obo:PDRO_0000059 a rdfs:Class ;
  rdfs:label "exactly some time elapsed since previous dose condition"@en , "condition sur le temps exactement écoulé depuis une précédente administration de dose"@fr ;
  rdfs:comment "A time elapsed since previous dose condition that is true if and only if the time having elapsed is equal to some duration."@en , "Une condition sur le temps écoulé depuis une dose antérieure qui est vraie si et seulement si le temps écoulé est égal à une certaine durée."@fr ;
  rdfs:subClassOf obo:PDRO_0000071 .

obo:PDRO_0000005 a rdfs:Class ;
  rdfs:label "document creation time identification"@en , "identification de l'instant de création d'un document"@fr ;
  rdfs:comment "A textual entity that denotes the time of document creation."@en , "Une entité textuelle indiquant l'instant de création d'un document."@fr ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UBERON_0001062 a rdfs:Class ;
  rdfs:label "anatomical entity" ;
  rdfs:comment "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:PATO_0001241 a rdfs:Class ;
  rdfs:label "physical object quality" ;
  rdfs:comment "A quality which inheres in a continuant." ;
  rdfs:subClassOf obo:BFO_0000019 , obo:PATO_0000001 .

obo:DRON_00000031 a rdfs:Class ;
  rdfs:label "drug administration"@en , "administration de médicament"@fr ;
  rdfs:comment "a treatment that has as participants an extended organism and a drug product and that results in part of the drug product being located in the extended organism."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OMRSE_00000172 a rdfs:Class ;
  rdfs:label "health care function"@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:BFO_0000141 a rdfs:Class ;
  rdfs:label "immaterial entity"@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:PDRO_0000320 a rdfs:Class ;
  rdfs:label "dosing frequency specification"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PDRO_0000056 a rdfs:Class ;
  rdfs:label "current time is after some instant condition"@en , "condition situant la période actuelle après un instant"@fr ;
  rdfs:comment "A condition that is true if and only if the current time is after some instant."@en , "Une condition qui est vraie si et seulement si l’instant présent est postérieur à un instant donné."@fr ;
  rdfs:subClassOf obo:PDRO_0000072 .

obo:PDRO_0000037 a rdfs:Class ;
  rdfs:label "non-generic drug product proprietary label"@en , "nom propriétaire d'un médicament non-générique"@fr ;
  rdfs:comment "A drug product name given to a non-generic drug product by the pharmaceutical company that produces it."@en , "Un nom de médicament non-générique donné par l'entreprise pharmaceutique qui le produit."@fr ;
  rdfs:subClassOf obo:PDRO_0000312 .

obo:IAO_0000028 a rdfs:Class ;
  rdfs:label "symbol"@en ;
  rdfs:comment "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000011 a rdfs:Class ;
  rdfs:label "spatiotemporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity"@en ;
  rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:OMIABIS_0001035 a rdfs:Class ;
  rdfs:label "survey execution"@en ;
  rdfs:comment "A planned process that realizes the concretization of a survey to generate an output(survey data.)"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:PATO_0000918 a rdfs:Class ;
  rdfs:label "volume" ;
  rdfs:comment "A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies." ;
  rdfs:subClassOf obo:PATO_0001710 .

obo:PDRO_0000128 a rdfs:Class ;
  rdfs:label "starting drug administration condition"@en , "condition de début d’administration de médicament"@fr ;
  rdfs:comment "A condition whose truthfulness is a prerequisite for starting a drug administration."@en , "Une condition dont la véracité est un prérequis pour commencer une administration de médicament."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:PDRO_0000009 a rdfs:Class ;
  rdfs:label "drug product characteristic specification"@en , "caractérisation de médicament prescrit"@fr ;
  rdfs:comment "An information content entity that specifies one or several characteristics of a drug product."@en , "Une entité de contenu informationnel qui spécifie une caractéristique d’un médicament prescrit."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMRSE_00000050 a rdfs:Class ;
  rdfs:label "Homo sapiens role"@en ;
  rdfs:subClassOf obo:OMRSE_00000049 .

obo:PDRO_0000191 a rdfs:Class ;
  rdfs:label "prescription drug administration specification"@en ;
  rdfs:comment "A drug administration specification that is part of a drug prescription."@en ;
  rdfs:subClassOf obo:PDRO_0010022 .

obo:UO_0000095 a rdfs:Class ;
  rdfs:label "volume unit" ;
  rdfs:comment "\"A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas.\" [NIST:NIST]" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:PDRO_0000324 a rdfs:Class ;
  rdfs:label "drug product characterization"@en ;
  rdfs:comment "An information content entity specifying a drug product, wether by its name, class, family or context of its intake."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PDRO_0000308 a rdfs:Class ;
  rdfs:label "complete drug administration specification"@en ;
  rdfs:comment """WIP An action specification that specifies a drug administration.

It specifies:
- The drug product
- The posology

It may also specify a starting drug administration condition""" ;
  rdfs:subClassOf obo:PDRO_0010022 .

obo:PDRO_0000088 a rdfs:Class ;
  rdfs:label "pharmacist role"@en , "rôle de pharmacien"@fr ;
  rdfs:comment "A health care provider role where the service provided is that of identification, preparation, dispensing and monitoring of pharmaceutical drugs."@en , "Un role de prestataire de soin qui fournit un service d'identification, de préparation, de distribution et de contrôle de médicaments."@fr ;
  rdfs:subClassOf obo:OMRSE_00000012 .

obo:PDRO_0000044 a rdfs:Class ;
  rdfs:label "drug product name"@en , "nom de médicament"@fr ;
  rdfs:comment "A textual entity denoting a class of drug product, that has as parts a drug product label, and typically a dose form specification and a drug strength specification."@en , "Une entité textuelle qui fait référence à un type de médicament."@fr ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000577 a rdfs:Class ;
  rdfs:label "centrally registered identifier symbol"@en ;
  rdfs:comment "A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:PDRO_0000313 a rdfs:Class ;
  rdfs:label "Anatomical Therapeutic Chemical code"@en ;
  rdfs:subClassOf obo:IAO_0000577 .

obo:BFO_0000027 a rdfs:Class ;
  rdfs:label "object aggregate"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000100 a rdfs:Class ;
  rdfs:label "data set"@en ;
  rdfs:comment "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OGMS_0000039 a rdfs:Class ;
  rdfs:label "configuration" ;
  rdfs:comment "A quality which is an spatial arrangement or distribution of a(n) independent continuant(s) across a Three Dimensional Region."@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:PDRO_0033203 a rdfs:Class ;
  rdfs:label "INN name"@en , "nom INN"@fr ;
  rdfs:comment "An active ingredient name that is an International Nonproprietary Name."@en , "Un nom d'ingrédient actif qui est un International Nonproprietary Name."@fr ;
  rdfs:subClassOf obo:PDRO_0040002 .

obo:PDRO_0000117 a rdfs:Class ;
  rdfs:label "dose range specification"@en , "spécification d’intervalle de dose"@fr ;
  rdfs:comment "An information content entity that specifies the minimum and maximum quantities of drug product or active ingredient in a dose administration."@en , "Une entité de contenu informationnel qui spécifie les quantités minimum et maximum de médicament ou d’ingrédient actif dans une administration de dose."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role"@en ;
  rdfs:comment "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:PDRO_0000316 a rdfs:Class ;
  rdfs:label "drug prescription ending validity temporal specification"@en ;
  rdfs:subClassOf obo:PDRO_0000311 .

obo:PDRO_0040002 a rdfs:Class ;
  rdfs:label "active ingredient name"@en , "nom d'ingrédient actif"@fr ;
  rdfs:comment "A textual entity that allows the identification of an active ingredient."@en , "Une entité textuelle qui permet l'identification d'un ingrédient actif."@fr ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PDRO_0010051 a rdfs:Class ;
  rdfs:label "greater than total dosage condition"@en , "condition de dosage total supérieur à une certaine quantité"@fr ;
  rdfs:comment "A total dosage condition that is true if and only if the total dosage administered is greater than a specified amount."@en , "une condition de dosage total où le dosage total administré est supérieur à une certaine quantité."@fr ;
  rdfs:subClassOf obo:PDRO_0010049 .

obo:PDRO_0000139 a rdfs:Class ;
  rdfs:label "minimum dosing interval condition"@en , "condition d’intervalle de dosage minimum"@fr ;
  rdfs:comment "A dosing condition that is true if and only if the amount of time that has elapsed since the previous dose is greater than some duration."@en , "Une condition de dosage qui est vraie si et seulement si le temps écoulé depuis la précédente dose est supérieur à une certaine valeur."@fr ;
  rdfs:subClassOf obo:PDRO_0000147 .

obo:GO_0003674 a rdfs:Class ;
  rdfs:label "molecular_function" ;
  rdfs:comment "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:PDRO_0010040 a rdfs:Class ;
  rdfs:label "current time condition"@en , "condition sur le temps présent"@fr ;
  rdfs:comment "A condition that describes the current time period relative to some other time period."@en , "Une condition situant la période actuelle relativement à une autre période."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:OMRSE_00000061 a rdfs:Class ;
  rdfs:label "architectural structure"@en ;
  rdfs:comment "A material entity that is a human made strcuture with firm connection between its foundation and the ground."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:PDRO_0010036 a rdfs:Class ;
  rdfs:label "pharmacological unit"@en , "unité pharmacologique"@fr ;
  rdfs:comment "A measurement unit label for the amount of a substance based on a specified biological activity or effect of that substance."@en , "Un label d'unité de mesure pour la quantité de substance fondé sur une activité biologique spécifiée ou sur un effet de cette substance."@fr ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:DRON_00000005 a rdfs:Class ;
  rdfs:label "clinical drug product"@en ;
  rdfs:comment "A drug product that is bearer of a clinical drug role."@en ;
  rdfs:subClassOf obo:BFO_0000040 , obo:DRON_00000074 .

obo:OPMI_0000096 a rdfs:Class ;
  rdfs:label "person last name"@en ;
  rdfs:subClassOf obo:OPMI_0000094 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity"@en ;
  rdfs:comment "A generically dependent continuant that is about some thing."@en ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:PDRO_0000200 a rdfs:Class ;
  rdfs:label "drug administration cessation prescription item"@en ;
  rdfs:comment "A drug prescription item that specifies the cessation of the administration of a drug."@en ;
  rdfs:subClassOf obo:PDRO_0000195 .

obo:OPMI_0000100 a rdfs:Class ;
  rdfs:label "birth name"@en ;
  rdfs:comment "A person name that is given at birth" ;
  rdfs:subClassOf obo:OPMI_0000094 .

obo:PDRO_0010080 a rdfs:Class ;
  rdfs:label "route of administration category specification"@en , "spécification de la catégorie de la voie d'administration"@fr ;
  rdfs:comment "A category value specification that specifies one route of administration from a standardized list of possible routes."@en , "Une spécification de valeur catégorique qui spécifie une voie d'administration."@fr ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:PDRO_0012001 a rdfs:Class ;
  rdfs:label "non-generic drug product"@en , "médicament non-générique"@fr ;
  rdfs:comment "A drug product that is not a generic drug product."@en , "Un médicament qui n’est pas un médicament générique."@fr ;
  rdfs:subClassOf obo:DRON_00000074 .

obo:OMRSE_00000027 a rdfs:Class ;
  rdfs:label "organization health care role"@en ;
  rdfs:comment "An organization social role that is realized by a health care process."@en ;
  rdfs:subClassOf obo:OMRSE_00000025 .

obo:BFO_0000001 a rdfs:Class ;
  rdfs:label "entity"@en .

obo:PDRO_0000123 a rdfs:Class ;
  rdfs:label "dose quantification specification"@en , "spécification de quantification de dose"@fr ;
  rdfs:comment "An information content entity that specifies how a dose is quantified in a dose administration."@en , "Une entité de contenu informationnel qui quantifie une dose dans une administration de dose."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:NCBITaxon_9606 a rdfs:Class ;
  rdfs:label "Homo sapiens" ;
  rdfs:subClassOf obo:COB_0000022 .

obo:PDRO_0000103 a rdfs:Class ;
  rdfs:label "prescribed dosing specification"@en , "spécification de dosage prescrit"@fr ;
  rdfs:comment "A directive information entity that directs the dosing in a drug administration."@en , "Une entité informationnelle directive qui dirige le dosage d’une administration de médicament."@fr ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:PDRO_0000072 a rdfs:Class ;
  rdfs:label "present time instant condition"@en , "condition sur l’instant présent"@fr ;
  rdfs:comment "A current time condition where the current time is described in relation to a temporal instant."@en , "une condition sur la période actuelle situant la période actuelle relativement à un instant donné."@fr ;
  rdfs:subClassOf obo:PDRO_0010040 .

obo:PDRO_0000092 a rdfs:Class ;
  rdfs:label "after some dose administration condition"@en , "condition de fin d’administration de dose"@fr ;
  rdfs:comment "A condition that is true if and only if some dose administration has ended."@en , "Une condition qui est vraie si et seulement une certaine administration de dose est finie."@fr ;
  rdfs:subClassOf obo:PDRO_0000090 .

obo:PDRO_0010031 a rdfs:Class ;
  rdfs:label "pharmacological unit value specification"@en , "spécification de valeur d'unité pharmacologique"@fr ;
  rdfs:comment "A scalar value specification that specifies the value of an active ingredient aggregate biological activity."@en , "Une spécification de valeur scalaire qui indique la valeur d'activité biologique d'un aggrégat d'ingrédient actif."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:PDRO_0000055 a rdfs:Class ;
  rdfs:label "current time is before some instant condition"@en , "condition de borne supérieure sur l’instant présent"@fr ;
  rdfs:comment "A condition that is true if and only if the current time is before some instant."@en , "Une condition qui est vraie si et seulement si l’instant présent est antérieur à un instant donné."@fr ;
  rdfs:subClassOf obo:PDRO_0000072 .

obo:PDRO_0000112 a rdfs:Class ;
  rdfs:label "rate of administration specification"@en , "spécification de taux d’administration"@fr ;
  rdfs:comment "An information content entity specifying a rate of a drug administration."@en , "Une entité de contenu informationnel spécifiant un taux d’administration de médicament."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000026 a rdfs:Class ;
  rdfs:label "one-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:DRON_00000001 a rdfs:Class ;
  rdfs:label "clinical drug role"@en ;
  rdfs:comment "A role of a material entity to prevent, diagnose, treat, or study disease and/or its effects."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OGMS_0000024 a rdfs:Class ;
  rdfs:label "sign" ;
  rdfs:comment "A quality of a patient, a material entity that is part of a patient, or a processual entity that a patient participates in, any one of which is observed in a physical examination and is deemed by the clinician to be of clinical significance."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:IAO_0000007 a rdfs:Class ;
  rdfs:label "action specification"@en ;
  rdfs:comment "a directive information entity that describes an action the bearer will take"@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:PATO_0000051 a rdfs:Class ;
  rdfs:label "morphology" ;
  rdfs:comment "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:PDRO_0000096 a rdfs:Class ;
  rdfs:label "drug dispensing specification"@en , "spécification de distribution de médicament"@fr ;
  rdfs:comment "An action specification that specifies the dispensing of a drug product."@en ;
  rdfs:subClassOf obo:IAO_0000007 .

obo:PDRO_0000004 a rdfs:Class ;
  rdfs:label "active ingredient aggregate mass"@en , "masse d'aggrégat d'ingrédient actif"@fr ;
  rdfs:comment "The mass of an active ingredient aggregate."@en , "La masse d'un aggrégat d'ingrédient actif."@fr ;
  rdfs:subClassOf obo:PATO_0000125 .

obo:BFO_0000004 a rdfs:Class ;
  rdfs:label "independent continuant"@en ;
  rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:PDRO_0000199 a rdfs:Class ;
  rdfs:label "drug administration modification prescription item"@en ;
  rdfs:comment "A drug administration prescription item that specifies the modification of the administration of a drug product."@en ;
  rdfs:subClassOf obo:PDRO_0000196 .

obo:BFO_0000146 a rdfs:Class ;
  rdfs:label "two-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:PDRO_0000066 a rdfs:Class ;
  rdfs:label "day of the week category specification"@en , "spécification de catégorie de jour de la semaine"@fr ;
  rdfs:comment "A category value specification that specifies one day of the week."@en , "Une spécification de valeur catégorique qui spécifie un jour de la semaine."@fr ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:UO_0000105 a rdfs:Class ;
  rdfs:label "frequency unit" ;
  rdfs:comment "\"A unit which is a standard measure of the number of repetitive actions in a particular time.\" [NIST:NIST]" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:PDRO_0000061 a rdfs:Class ;
  rdfs:label "time of the day"@en , "moment de la journée"@fr ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process"@en ;
  rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:PDRO_0010035 a rdfs:Class ;
  rdfs:label "active ingredient molar value specification"@en , "spécification de valeur molaire d'ingrédient actif"@fr ;
  rdfs:comment "A substance value specification where the substance is an active ingredient aggregate."@en , "Une spécification de quantité de substance où la substance est un aggrégat d'ingrédient actif."@fr ;
  rdfs:subClassOf obo:PDRO_0010032 .

obo:PDRO_0000011 a rdfs:Class ;
  rdfs:label "drug product information item"@en , "élément d'information sur un médicament"@fr ;
  rdfs:comment "A data item that is about a drug product."@en , "Un élément de données qui fournit une information sur un médicament."@fr ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMRSE_00000023 a rdfs:Class ;
  rdfs:label "collection of humans"@en ;
  rdfs:comment "An object aggregate all of whose components are human beings."@en ;
  rdfs:subClassOf obo:OMRSE_00000022 .

obo:OBI_0001929 a rdfs:Class ;
  rdfs:label "mass value specification" ;
  rdfs:comment "A value specification that specifies the mass of some thing." ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:PDRO_0000305 a rdfs:Class ;
  rdfs:label "drug administration modification condition"@en , "condition de modification d’administration de médicament"@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:PDRO_0000000 a rdfs:Class ;
  rdfs:label "time elapsed since dispensing condition"@en , "condition indiquant le temps écoulé depuis une distribution"@fr ;
  rdfs:comment "a condition describing the time elapsed since a drug dispensing process."@en , "une condition de temps écoulé depuis une distribution de médicaments."@fr ;
  rdfs:subClassOf obo:PDRO_0010041 .

obo:PDRO_0000195 a rdfs:Class ;
  rdfs:label "drug prescription item"@en ;
  rdfs:comment "A directive information entity that is a part of a drug prescription and specifies some action(s) related to one or several drugs. It is intended to direct some actions to be performed by a patient and some pharmacist(s). It may also specify a healthcare objective."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:PDRO_0020006 a rdfs:Class ;
  rdfs:label "generic drug product"@en , "médicament générique"@fr ;
  rdfs:comment "A drug product that was approved and commercialized after the patent for that drug product expired."@en , "Une médicament qui a été approuvé et commercialisé après l'expiration du brevet correspondant."@fr ;
  rdfs:subClassOf obo:DRON_00000074 .

obo:PDRO_0000026 a rdfs:Class ;
  rdfs:label "drug strength item"@en , "élément d'information de force médicamenteuse"@fr ;
  rdfs:comment "A drug product information item that is about one or more magnitudes of biological activity, masses or quantities of active ingredient aggregate per unit quantity of a drug product."@en , "Un élément d'information sur un médicament à propos de une ou plusieurs magnitudes d'activité biologique, masses ou quantités d'aggrégat d'ingrédient actif par unité de médicament."@fr ;
  rdfs:subClassOf obo:PDRO_0000011 .

obo:PDRO_0010025 a rdfs:Class ;
  rdfs:label "drug product mass value specification"@en , "spécification de valeur de masse de médicament"@fr ;
  rdfs:comment "A mass value specification that specifies the mass of a drug product."@en , "Une spécification de valeur de masse qui indique la masse d'un médicament."@fr ;
  rdfs:subClassOf obo:OBI_0001929 .

obo:BFO_0000009 a rdfs:Class ;
  rdfs:label "two-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:PDRO_0000127 a rdfs:Class ;
  rdfs:label "continuing drug administration condition"@en , "condition de continuation d’administration de médicament"@fr ;
  rdfs:comment "A condition whose truthfulness is a prerequisite for continuing a drug administration."@en , "Une condition dont la véracité est un pré-requis pour continuer une administration de médicament."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:BFO_0000028 a rdfs:Class ;
  rdfs:label "three-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:OBI_0001930 a rdfs:Class ;
  rdfs:label "categorical value specification" ;
  rdfs:comment "A value specification that is specifies one category out of a fixed number of nominal categories" ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:CHEBI_23367 a rdfs:Class ;
  rdfs:label "molecular entity" ;
  rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ;
  rdfs:subClassOf obo:BFO_0000030 , obo:CHEBI_24431 .

obo:OBI_0002139 a rdfs:Class ;
  rdfs:label "volume value specification"@en , "spécification de valeur de volume"@fr ;
  rdfs:comment "A value specification that specifies the volume of some thing." ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:PDRO_0010010 a rdfs:Class ;
  rdfs:label "health care objective specification"@en , "spécification d'objectif de santé"@fr ;
  rdfs:comment "An objective specification that specifies the objective of a health care process."@en , "Une spécification d'objectif d'un processus de soin ou d'une de ses parties."@fr ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:BFO_0000142 a rdfs:Class ;
  rdfs:label "one-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:PDRO_0010043 a rdfs:Class ;
  rdfs:label "less than some number of doses per unit time condition"@en , "condition indiquant que le nombre de doses par unité de temps est inférieur à"@fr ;
  rdfs:comment "A number of doses condition  that is true if and only if the number of dose administrations having occurred is less than a specified number."@en , "une condition décrivant le nombre de doses par unité de temps comme étant inférieur à un certain nombre d'administration de doses."@fr ;
  rdfs:subClassOf obo:PDRO_0010042 .

obo:OMRSE_00000012 a rdfs:Class ;
  rdfs:label "health care provider role"@en ;
  rdfs:comment "A human health care role inhering in an organization or human being that is realized by a process of providing health care services to an organism."@en ;
  rdfs:subClassOf obo:OMRSE_00000010 .

obo:PDRO_0010048 a rdfs:Class ;
  rdfs:label "less than some number of dispensings condition"@en , "condition indiquant qu'un nombre de distributions passées est plus petit qu'un certain nombre"@fr ;
  rdfs:comment "A number of dispensings condition that is true if and only if the number of dispensings having occurred is less than a specified number."@en , "Un condition de nombre de distributions indiquant qu'un nombre de distributions passées est plus petit qu'un certain nombre."@fr ;
  rdfs:subClassOf obo:PDRO_0010046 .

obo:PDRO_0000022 a rdfs:Class ;
  rdfs:label "drug strength specification"@en , "spécification de force médicamenteuse"@fr ;
  rdfs:comment "An information content entity that specifies the strength of a drug product."@en , "Une entité de contenu informationnel qui spécifie la force d’un médicament prescrit."@fr ;
  rdfs:subClassOf obo:PDRO_0000009 .

obo:CHEBI_24431 a rdfs:Class ;
  rdfs:label "chemical entity" ;
  rdfs:comment "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000104 a rdfs:Class ;
  rdfs:label "plan specification"@en ;
  rdfs:comment "A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:PDRO_0000100 a rdfs:Class ;
  rdfs:label "drug dispensing process"@en , "processus de distribution de médicament"@fr ;
  rdfs:comment "A planned process in which a health care provider or person who is part of a health care organization provides a determinate quantity of a particular drug product for use in a particular patient."@en , "Un processus planifié pendant lequel un professionnel de santé ou une personne faisant partie d'une organisation de santé fournit une quantité déterminée d'un médicament particulier à destination d'un patient particulier."@fr ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OMRSE_00000010 a rdfs:Class ;
  rdfs:label "human health care role"@en ;
  rdfs:comment "A role in human social processes that is realized by health care processes such as seeking or providing treatment for disease and injury, diagnosing disease and injury, or undergoing diagnosis. "@en ;
  rdfs:subClassOf obo:OMRSE_00000024 .

obo:BFO_0000008 a rdfs:Class ;
  rdfs:label "temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:PDRO_0000078 a rdfs:Class ;
  rdfs:label "number of doses in drug administration condition"@en , "condition de nombre d’administration de doses"@fr ;
  rdfs:comment "A condition involving the number of doses administered in some drug administration."@en , "Une condition faisant intervenir le nombre de doses administrées dans une administration de médicament."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:PDRO_0000197 a rdfs:Class ;
  rdfs:label "drug administration initiation precription item"@en ;
  rdfs:comment "A drug administration prescription item that specifies the initiation of the administration of a drug."@en ;
  rdfs:subClassOf obo:PDRO_0000196 .

obo:OMRSE_00000049 a rdfs:Class ;
  rdfs:label "organism role"@en ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:IAO_0000033 a rdfs:Class ;
  rdfs:label "directive information entity"@en ;
  rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PDRO_0000058 a rdfs:Class ;
  rdfs:label "greater than some time elapsed since previous dose condition"@en , "condition sur le temps minimal écoulé depuis une précédente administration de dose"@fr ;
  rdfs:comment "A time elapsed since previous dose condition  that is true if and only if the time having elapsed is greater than some duration."@en , "Une condition sur le temps écoulé depuis une dose antérieure qui est vraie si et seulement si le temps écoulé est plus grand qu’une certaine durée."@fr ;
  rdfs:subClassOf obo:PDRO_0000071 .

obo:PATO_0001710 a rdfs:Class ;
  rdfs:label "3-D extent" ;
  rdfs:comment "A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions." ;
  rdfs:subClassOf obo:PATO_0000117 .

obo:PDRO_0010050 a rdfs:Class ;
  rdfs:label "less than or equal to total dosage condition"@en , "condition de dosage total inférieur ou égal à une certaine quantité"@fr ;
  rdfs:comment "A total dosage condition that is true if and only if the total dosage administered is less or equal to a specified amount."@en , "une condition de dosage total où le dosage total administré est inférieur ou égal à une certaine quantité."@fr ;
  rdfs:subClassOf obo:PDRO_0010049 .

obo:PDRO_0000115 a rdfs:Class ;
  rdfs:label "mass per time unit"@en , "unité de masse par unité de temps"@fr ;
  rdfs:comment "A measurement unit label of mass per time."@en , "Une unité de mesure de masse par temps."@fr ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:OBI_0000011 a rdfs:Class ;
  rdfs:label "planned process"@en ;
  rdfs:comment "A processual entity that realizes a plan which is the concretization of a plan specification."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:PDRO_0000051 a rdfs:Class ;
  rdfs:label "drug dose form specification"@en , "spécification de forme de dose médicamenteuse"@fr ;
  rdfs:comment "An information content entity that specifies the dose form of a drug product."@en , "Une entité de contenu informationnelle qui spécifie la forme de dose d’un médicament prescrit."@fr ;
  rdfs:subClassOf obo:PDRO_0000009 .

obo:OBI_0001931 a rdfs:Class ;
  rdfs:label "scalar value specification" ;
  rdfs:comment "A value specification that consists of two parts: a numeral and a unit label" ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:PDRO_0000319 a rdfs:Class ;
  rdfs:label "health care prescription identifier"@en ;
  rdfs:subClassOf obo:IAO_0000577 .

obo:PDRO_0000021 a rdfs:Class ;
  rdfs:label "active ingredient mass value specification"@en , "spécification de valeur de masse d'ingrédient actif"@fr ;
  rdfs:comment "A mass value specification that specifies the mass of an active ingredient aggegate."@en , "Une spécification de valeur de masse indiquant la masse d'un aggrégat d'ingrédient actif."@fr ;
  rdfs:subClassOf obo:OBI_0001929 .

obo:BFO_0000002 a rdfs:Class ;
  rdfs:label "continuant"@en ;
  rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:PDRO_0000318 a rdfs:Class ;
  rdfs:label "drug prescription starting validity temporal specification"@en ;
  rdfs:subClassOf obo:PDRO_0000310 .

obo:PDRO_0000202 a rdfs:Class ;
  rdfs:label "pharmacist record item"@en ;
  rdfs:comment "A directive information entity that is a part of a pharmacist report and that specifies some action(s) related to one or several drugs. It is typically intended to direct some actions to be performed by a patient and pharmacist(s)."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OMRSE_00000033 a rdfs:Class ;
  rdfs:label "aggregate of organizations"@en ;
  rdfs:comment "An object aggregate that is not itself an organization and whose members are only organizations that have some feature in common"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OMRSE_00000020 a rdf:Property ;
  rdfs:label "is-aggregate-of" ;
  rdfs:comment """We anticipate BFO 2.0 including and defining this relation.  When it does, we will obsolete this property and declare it equivalent to the BFO 2.0 relation.
"""@en ;
  rdfs:range obo:OBI_0000245 .

obo:PDRO_0000126 a rdfs:Class ;
  rdfs:label "active ingredient mass delivery rate value specification"@en , "spécification de taux d’administration de masse d’ingrédient actif"@fr ;
  rdfs:comment "A value specification specifying the value of an active ingredient mass delivery rate."@en , "Une spécification de valeur spécifiant la valeur du taux d’administration de masse d’ingrédient actif."@fr ;
  rdfs:subClassOf obo:PDRO_0000121 .

obo:PDRO_0000160 a rdfs:Class ;
  rdfs:label "initial drug dispensing process"@en , "processus de distribution de médicament initiale"@fr ;
  rdfs:comment "A drug dispensing process that is the first time the patient is being provided with a particular drug following a particular prescription."@en , "Un processus de distribution de médicament tel que ce médicament n'a jamais été fourni au patient auparavant sur la base de cette prescription particulière."@fr ;
  rdfs:subClassOf obo:PDRO_0000100 .

obo:GO_0016301 a rdfs:Class ;
  rdfs:label "kinase activity" ;
  rdfs:comment "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ;
  rdfs:subClassOf obo:GO_0003674 .

obo:PDRO_0010024 a rdfs:Class ;
  rdfs:label "drug product volume value specification"@en , "spécification de valeur de volume de médicament"@fr ;
  rdfs:comment "A volume value specification where the volume specified is that of a drug product."@en , "Une spécification de valeur de volume indiquant le volume d'un médicament."@fr ;
  rdfs:subClassOf obo:OBI_0002139 .

obo:PDRO_0010034 a rdfs:Class ;
  rdfs:label "drug product volumetric flow rate value specification"@en , "spécification de valeur de rythme de médicament"@fr ;
  rdfs:comment "A rate value specification that specifies the rate at which a drug product is administered during a dose administration."@en , "Une spécification de valeur de rythme qui indique le rythme auquel un médicament est administré pendant une administration de dose."@fr ;
  rdfs:subClassOf obo:PDRO_0010033 .

obo:PDRO_0000040 a rdfs:Class ;
  rdfs:label "presence of sign condition"@en , "condition indiquant la présence d'un signe"@fr ;
  rdfs:comment "a condition  that is true if and only if some sign is present in an individual."@en , "Une condition qui est vraie si et seulement si un certain signe est présent chez un individu."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:PDRO_0000080 a rdfs:Class ;
  rdfs:label "drug selection"@en , "sélection de médicament"@fr ;
  rdfs:comment "A process where a health care provider physically selects a particular drug product as specified in a drug product specification."@en , "Un processus dans lequel un fournisseur de soin sélectionne physiquement un médicament particulier comme indiqué sur une spécification de médicament."@fr ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:PDRO_0000028 a rdfs:Class ;
  rdfs:label "drug strength per volume unit item"@en , "élément d'information de force médicamenteuse par unité de volume"@fr ;
  rdfs:comment "A drug strength item where the unit quantity is a unit of volume."@en , "Un élément d'information de force médicamenteuse où l'unité de quantité de médicament est une unité de volume."@fr ;
  rdfs:subClassOf obo:PDRO_0000026 .

obo:PDRO_0000315 a rdfs:Class ;
  rdfs:label "drug dispensing starting validity temporal specification"@en ;
  rdfs:subClassOf obo:PDRO_0000310 .

obo:PDRO_0000321 a rdfs:Class ;
  rdfs:label "specification of a part of a drug prescription validity period"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PDRO_0000192 a rdfs:Class ;
  rdfs:label "pharmacist dispensing drug administration specification"@en ;
  rdfs:comment "A drug administration specification written by a pharmacist on the basis of a drug administration specification written by a prescriber."@en ;
  rdfs:subClassOf obo:PDRO_0010022 .

obo:PDRO_0000084 a rdfs:Class ;
  rdfs:label "greater than some time elapsed since the previous dispensing condition"@en , "condition de temps minimum passé depuis une distribution de médicament"@fr ;
  rdfs:comment "a condition  that is true if and only if the time elapsed since some dispensing is greater than some duration."@en , "Une condition qui est vraie si et seulement si le temps écoulé depuis une certaine distribution est plus grand qu’une certaine durée."@fr ;
  rdfs:subClassOf obo:PDRO_0000000 .

obo:PDRO_0000036 a rdfs:Class ;
  rdfs:label "drug active ingredient item"@en , "élément d'information d'ingrédient médicamenteux"@fr ;
  rdfs:comment "A drug product information item that is about an active ingredient in a drug product."@en , "Un élément d'information sur un médicament dénotant un de ses ingrédients."@fr ;
  rdfs:subClassOf obo:PDRO_0000011 .

obo:PDRO_0000003 a rdfs:Class ;
  rdfs:label "patient identification"@en , "identification d'un patient"@fr ;
  rdfs:comment "A written name denoting a particular patient."@en , "Un nom écrit faisant référence à un patient particulier."@fr ;
  rdfs:subClassOf obo:IAO_0000590 .

obo:BFO_0000019 a rdfs:Class ;
  rdfs:label "quality"@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:OPMI_0000097 a rdfs:Class ;
  rdfs:label "person middle name"@en ;
  rdfs:subClassOf obo:OPMI_0000094 .

obo:PDRO_0000062 a rdfs:Class ;
  rdfs:label "month of the year"@en , "mois de l'année"@fr ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:BFO_0000035 a rdfs:Class ;
  rdfs:label "process boundary"@en ;
  rdfs:comment "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:PDRO_0000193 a rdfs:Class ;
  rdfs:label "prescription drug dispensing specification"@en ;
  rdfs:comment "A drug dispensing specification that is part of a prescription and authorizes the dispensing of a drug product under certain conditions, and usually specifies how much of the drug is to be dispensed at a time and how many times in total."@en ;
  rdfs:subClassOf obo:PDRO_0000096 .

obo:OMIABIS_0000060 a rdfs:Class ;
  rdfs:label "survey data"@en ;
  rdfs:comment "A data set that contains the outcome of a survey."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000312 a rdf:Property ;
  rdfs:label "is_specified_output_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:OMIABIS_0001035 ;
  rdfs:subPropertyOf obo:RO_0000056 .

<http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> a rdfs:Class .

obo:OGMS_0000103 a rdfs:Class ;
  rdfs:label "disease prophylaxis" ;
  rdfs:comment "A planned process whose completion is hypothesized by a health care provider to reduce the risk of developing a disorder or the signs and symptoms of a disorder."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:PDRO_0000201 a rdfs:Class ;
  rdfs:label "pharmacist record"@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:PDRO_0000074 a rdfs:Class ;
  rdfs:label "pharmacy facility"@en , "établissement de pharmacologie"@fr ;
  rdfs:comment "A health care facility whose function is to store, prepare, dispense, and monitor the usage of pharmaceutical drugs among patients in a given area or encountered in a given health care provider organization."@en , "Un établissement de santé qui a pour fonction d'entreposer, préparer, distribuer et surveiller l'utilisation des médicaments parmi les patients d'une zone géographique donnée ou suivis dans une organisation de soin donnée."@fr ;
  rdfs:subClassOf obo:OMRSE_00000102 .

obo:PDRO_0000310 a rdfs:Class ;
  rdfs:label "starting validity temporal specification"@en , "spécification de début de période de validité"@fr ;
  rdfs:comment "A textual entity that denotes the starting time of a validity period." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PDRO_0000091 a rdfs:Class ;
  rdfs:label "after some drug administration condition"@en , "condition de fin d’administration de médicament"@fr ;
  rdfs:comment "A condition that is true  if and only if some drug administration has ended."@en , "Une condition qui est vraie si et seulement si une certaine administration de médicament est finie."@fr ;
  rdfs:subClassOf obo:PDRO_0000090 .

obo:PDRO_0000325 a rdfs:Class ;
  rdfs:label "reported drug administration description"@en ;
  rdfs:comment "A drug administration description that describes the administration of a drug self reported by the individual taking the drug."@en ;
  rdfs:subClassOf obo:PDRO_0000323 .

obo:DRON_00000074 a rdfs:Class ;
  rdfs:label "drug product"@en ;
  rdfs:comment "A material entity that (1) contains at least one scattered molecular aggregate as part and (2) is intended, when administered to an organism, to produce some therapeutic and/or psychoactive effect."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:PDRO_0010044 a rdfs:Class ;
  rdfs:label "greater than some number of doses per unit time condition"@en , "condition indiquant que le nombre de doses par unité de temps est supérieur à"@fr ;
  rdfs:comment "A number of doses condition  that is true if and only if the number of dose administrations having occurred is greater than a specified number."@en , "une condition décrivant le nombre de doses par unité de temps comme étant supérieur à un certain nombre d'administration de doses."@fr ;
  rdfs:subClassOf obo:PDRO_0010042 .

obo:BFO_0000020 a rdfs:Class ;
  rdfs:label "specifically dependent continuant"@en ;
  rdfs:comment "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:PDRO_0000070 a rdfs:Class ;
  rdfs:label "time elapsed since first dose condition"@en , "condition indiquant le temps écoulé depuis une première administration de dose"@fr ;
  rdfs:comment "a condition describing the time elapsed since the first dose administration of some drug administration."@en , "une condition de temps écoulé depuis la première administration de dose d'une certaine administration de médicament."@fr ;
  rdfs:subClassOf obo:PDRO_0010053 .

obo:IAO_0000578 a rdfs:Class ;
  rdfs:label "centrally registered identifier"@en ;
  rdfs:comment "An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PDRO_0000099 a rdfs:Class ;
  rdfs:label "metered dose administration count value specification"@en , "spécification de nombre de prise de dose"@fr ;
  rdfs:comment "A scalar value specification that specifies a number of metered dose administrations."@en , "Une spécification de valeur scalaire spécifiant le nombre d’administration de doses mesurées."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:HADO_0000006 a rdfs:Class ;
  rdfs:label "medical record identifier"@en ;
  rdfs:comment "A CRID symbol that is sufficent to look up a patient file in a medical record registry."@en ;
  rdfs:subClassOf obo:IAO_0000577 .

obo:PDRO_9876001 a rdfs:Class ;
  rdfs:label "administration dose form"@en , "forme de la dose d'administration"@fr ;
  rdfs:comment "The configuration of a drug product just before it is administered."@en , "La configuration d'un médicament juste avant qu'il soit administré."@fr ;
  rdfs:subClassOf obo:OGMS_0000039 .

obo:PDRO_0000077 a rdfs:Class ;
  rdfs:label "excipient name"@en , "nom d’excipient"@fr ;
  rdfs:comment "A textual entity that allows the identification of an excipient."@en , "Une entité textuelle qui permet l'identification d'un excipient."@fr ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PDRO_0000304 a rdfs:Class ;
  rdfs:label "pharmacist drug administration specification instruction"@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OGMS_0000020 a rdfs:Class ;
  rdfs:label "symptom" ;
  rdfs:comment "A quality of a patient that is observed by the patient or a processual entity experienced by the patient, either of which is hypothesized by the patient to be a realization of a disease."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:PDRO_0000314 a rdfs:Class ;
  rdfs:label "drug dispensing ending validity temporal specification"@en ;
  rdfs:subClassOf obo:PDRO_0000311 .

obo:PDRO_0000054 a rdfs:Class ;
  rdfs:label "generic drug product proprietary label"@en , "nom propriétaire d'un médicament générique"@fr ;
  rdfs:comment "A drug product name given to a generic drug product by the pharmaceutical company that produces it."@en , "Un nom de médicament générique donné par l'entreprise pharmaceutique qui le produit."@fr ;
  rdfs:subClassOf obo:PDRO_0000312 .

obo:PDRO_0000039 a rdfs:Class ;
  rdfs:label "dose administration"@en , "administration de dose"@fr ;
  rdfs:comment "A process that has as participants an extended organism and a drug product and that results in a specified portion of the drug product (a single dose) being located in the extended organism."@en , "Un processus ayant comme participants un organisme étendu et un médicament, à l'issue de laquelle une certaine dose du médicament est localisée dans l'organisme étendu."@fr ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0000245 a rdfs:Class ;
  rdfs:label "organization"@en ;
  rdfs:comment "An organization is a continuant entity which can play roles,  has members, and has a set of organization rules.  Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OMRSE_00000048 a rdfs:Class ;
  rdfs:label "material entity role"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OMRSE_00000051 a rdfs:Class ;
  rdfs:label "organization role"@en ;
  rdfs:subClassOf obo:BFO_0000023 , obo:OMRSE_00000048 .

obo:OMRSE_00000062 a rdfs:Class ;
  rdfs:label "facility"@en ;
  rdfs:comment "An architectural structure that bears some function."@en ;
  rdfs:subClassOf obo:OMRSE_00000061 .

obo:PDRO_0000122 a rdfs:Class ;
  rdfs:label "drug renewal process"@en , "processus de renouvellement de médicament"@fr ;
  rdfs:comment "A drug dispensing process that follows an initial drug dispensing process, such that both processes are specified in the same drug prescription."@en , "Un processus de distribution de médicament qui suit un processus de distribution initial, lorsque les deux processus sont indiqués dans la même prescription médicale."@fr ;
  rdfs:subClassOf obo:PDRO_0000100 .

obo:IAO_0000003 a rdfs:Class ;
  rdfs:label "measurement unit label"@en ;
  rdfs:comment "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:PDRO_0000307 a rdfs:Class ;
  rdfs:label "drug dispensing validity period specification"@en , "spécification de la période de validité de la distribution d'un médicament"@fr ;
  rdfs:comment "An 'information content entity' that specifies the validity period of a drug dispensing specification."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000109 a rdfs:Class ;
  rdfs:label "measurement datum"@en ;
  rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMRSE_00000015 a rdfs:Class ;
  rdfs:label "health care provider organization role"@en ;
  rdfs:comment "A role that inheres in an organization and that is realized by the providing of services in a health care encounter."@en ;
  rdfs:subClassOf obo:OMRSE_00000027 .

obo:PDRO_0010020 a rdfs:Class ;
  rdfs:label "diagnostic objective specification"@en , "spécification d'objectif diagnostique"@fr ;
  rdfs:comment "A health care objective specification specifying a diagnostic objective."@en , "Une spécification d'objectif de santé diagnostique."@fr ;
  rdfs:subClassOf obo:PDRO_0010010 .

obo:OPMI_0000324 a rdfs:Class ;
  rdfs:label "person first and last name"@en ;
  rdfs:comment "A person name that includes both the first and last name" ;
  rdfs:subClassOf obo:OPMI_0000094 .

obo:PDRO_0000109 a rdfs:Class ;
  rdfs:label "portion of drug product"@en , "portion de médicament"@fr ;
  rdfs:comment "A material entity that is a proper part of a drug product, with a similar composition as the drug product."@en , "Une entité matérielle qui est une partie propre d’un médicament, avec une composition similaire à celle du médicament."@fr ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:PDRO_0010038 a rdfs:Class ;
  rdfs:label "presence of symptom condition"@en , "condition indiquant la présence d'un symptôme"@fr ;
  rdfs:comment "A condition that is true if and only if some symptom is present in an individual."@en , "Une condition qui est vraie si et seulement si un certain symptôme est présent chez un individu."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:OBI_0001141 a rdfs:Class ;
  rdfs:label "individual organism identifier"@en ;
  rdfs:comment "a CRID symbol used to distinguish one individual organism from another."@en ;
  rdfs:subClassOf obo:IAO_0000577 .

obo:OMRSE_00000022 a rdfs:Class ;
  rdfs:label "aggregate of objectual organisms"@en ;
  rdfs:comment "An object aggregate of objectual organisms."@en ;
  rdfs:subClassOf obo:BFO_0000027 .

obo:PDRO_0000043 a rdfs:Class ;
  rdfs:label "less than some time elapsed since previous dose condition"@en , "condition sur le temps maximal écoulé depuis une précédente administration de dose"@fr ;
  rdfs:comment "A time elapsed since previous dose condition  that is true if and only if the time having elapsed is less than some duration."@en , "Une condition sur le temps écoulé depuis une dose antérieure qui est vraie si et seulement si le temps écoulé est plus petit qu’une certaine durée."@fr ;
  rdfs:subClassOf obo:PDRO_0000071 .

obo:PDRO_0010017 a rdfs:Class ;
  rdfs:label "drug dispensing amount specification"@en , "spécification de la quantité de médicament à distribuer"@fr ;
  rdfs:comment "An information content entity that describes the amount of a drug product to dispense in a single drug dispensing process."@en , "Une entité informationnelle qui indique la quantité de médicament à distribuer pendant un processus de distribution unique."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000102 a rdfs:Class ;
  rdfs:label "data about an ontology part"@en ;
  rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:PDRO_0010049 a rdfs:Class ;
  rdfs:label "total dosage condition"@en , "condition de dosage total"@fr ;
  rdfs:comment "a condition describing the amount of drug product or active ingredient that has been administered in a given duration of time."@en , "une condition décrivant la quantité de médicament ou d'ingrédient actif qui a été administrée pendant une certaine période de temps."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:PDRO_0000198 a rdfs:Class ;
  rdfs:label "drug administration continuation prescription item"@en ;
  rdfs:comment "A drug administration prescription item that specifies the continuation of the administration of a drug whose initiation was specified by a former drug prescription. The drug administration specification contained in the continuation prescription item is synonymous with the drug administration specification contained in the initiation prescription item of this former drug prescription."@en ;
  rdfs:subClassOf obo:PDRO_0000196 .

obo:PDRO_0000007 a rdfs:Class ;
  rdfs:label "drug administration and dispensing specification"@en , "spécification de distribution et d’administration de médicament"@fr ;
  rdfs:comment "A directive information entity that is composed by a drug administration specification and a drug dispensing specification."@en , "Une entité informationnelle directive qui est composée par une spécification d’administration de médicament et une spécification de distribution de médicament."@fr ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OMIABIS_0001026 a rdfs:Class ;
  rdfs:label "medical record"@en ;
  rdfs:comment "A document that contains information representing health-relevant qualities of a patient written in a chronological manner and that is primarily used for patient care in a clinical setting."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:PATO_0000001 a rdfs:Class ;
  rdfs:label "quality" ;
  rdfs:comment "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:PDRO_0000083 a rdfs:Class ;
  rdfs:label "greater than some number of doses have occurred condition"@en , "condition de nombre d’administration de doses minimum"@fr ;
  rdfs:comment "A number of doses in drug administration condition that is true if and only if more than some number of dose administrations have occurred."@en , "Une condition de nombre de doses d’administration de médicament qui est vraie si et seulement si plus d’un certain nombre d’administration de doses ont été effectuées."@fr ;
  rdfs:subClassOf obo:PDRO_0000078 .

obo:PDRO_0000125 a rdfs:Class ;
  rdfs:label "drug product quantification specification"@en , "spécification de quantité de médicament dans une dose"@fr ;
  rdfs:comment "A dose quantification specification that specifies the quantity of drug product administered in a dose administration."@en , "Une spécification de quantification de dose spécifiant la quantité de médicament administrée lors d’une administration de dose."@fr ;
  rdfs:subClassOf obo:PDRO_0000123 .

obo:OBI_0000093 a rdfs:Class ;
  rdfs:label "patient role"@en ;
  rdfs:comment "a role which inheres in a person and is realized by the process of being under the care of a physician or health care provider"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OPMI_0000094 a rdfs:Class ;
  rdfs:label "person name"@en ;
  rdfs:comment "A name of a person, which can have different types" ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PDRO_0000079 a rdfs:Class ;
  rdfs:label "exactly some number of doses in drug administration condition"@en , "condition de nombre exact d’administration de doses"@fr ;
  rdfs:comment "A number of doses in drug administration condition that is true if and only if exactly some number of dose administrations have occurred."@en , "Une condition de nombre de doses d’administration de médicament qui est vraie si et seulement si exactement un certain nombre d’administration de doses ont été effectuées."@fr ;
  rdfs:subClassOf obo:PDRO_0000078 .

obo:BFO_0000148 a rdfs:Class ;
  rdfs:label "zero-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:PDRO_0000203 a rdfs:Class ;
  rdfs:label "pharmacist drug dispensing record"@en ;
  rdfs:comment "A data item that is part of a pharmacist information system and specifies how much of a given drug product has been dispensed to a patient."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:PDRO_0000147 a rdfs:Class ;
  rdfs:label "dosing condition"@en , "condition de dosage"@fr ;
  rdfs:comment "A condition whose truthfulness is a prerequisite for the instruction of taking of a dose."@en , "Une condition dont la véracité est un prérequis pour une instruction de prise d’une dose."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:OBI_0000112 a rdfs:Class ;
  rdfs:label "specimen role"@en ;
  rdfs:comment "a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:PDRO_1000009 a rdfs:Class ;
  rdfs:label "drug preparation"@en , "préparation de médicament"@fr ;
  rdfs:comment "A process in which a drug product is modified in order to render it more suitable for patient administration."@en , "Un processus dans lequel un médicament est modifié de manière à le rendre plus approprié pour une administration au patient."@fr ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:PDRO_0000119 a rdfs:Class ;
  rdfs:label "active ingredient aggregate"@en , "aggrégat d'ingrédient actif"@fr ;
  rdfs:comment "A scattered molecular aggregate with the role of active ingredient."@en , "Un aggrégat de molécule dispersée avec le rôle d'ingrédient actif."@fr ;
  rdfs:subClassOf obo:OBI_0000576 .

obo:PATO_0001404 a rdfs:Class ;
  rdfs:label "nucleate quality" ;
  rdfs:comment "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei." ;
  rdfs:subClassOf obo:PATO_0001396 .

obo:PDRO_0010033 a rdfs:Class ;
  rdfs:label "volumetric flow rate value specification"@en , "spécification de valeur de rythme"@fr ;
  rdfs:comment "A scalar value specification whose unit label is a volumetric rate unit."@en , "Une spécification de valeur scalaire dont l'unité est une unité de rythme."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:OMRSE_00000025 a rdfs:Class ;
  rdfs:label "organization social role"@en ;
  rdfs:comment "A role in human social processes that inheres in an organization."@en ;
  rdfs:subClassOf obo:OMRSE_00000024 .

obo:OGMS_0000097 a rdfs:Class ;
  rdfs:label "health care encounter" ;
  rdfs:comment "A temporally-connected health care process that has as participants an organization or person realizing the health care provider role and a person realizing the patient role.  The health care provider role and patient are realized during the health care encounter"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:PATO_0000125 a rdfs:Class ;
  rdfs:label "mass" ;
  rdfs:comment "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:IAO_0000300 a rdfs:Class ;
  rdfs:label "textual entity"@en ;
  rdfs:comment "A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000003 a rdfs:Class ;
  rdfs:label "occurrent"@en ;
  rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:UO_0000270 a rdfs:Class ;
  rdfs:label "volumetric flow rate unit" ;
  rdfs:comment "\"A unit which is a standard measure of the volume of fluid which passes through a given surface per unit time .\" [Wikipedia:Wikipedia]" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:PDRO_0010028 a rdfs:Class ;
  rdfs:label "statement"@en , "énoncé"@fr ;
  rdfs:comment "An information content entity that describes some relationships between some entities and is intended to be evaluated as true or false."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:PDRO_0000121 a rdfs:Class ;
  rdfs:label "mass per time value specification"@en , "spécification de valeur de masse par unité de temps"@fr ;
  rdfs:comment "A scalar value specification that specifies a mass per time value specification."@en , "Une spécification de valeur scalaire qui spécifie une valeur de masse par unité de temps."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:PDRO_0000114 a rdfs:Class ;
  rdfs:label "site of administration category specification"@en , "spécification du site d'administration"@fr ;
  rdfs:comment "A category value specification that specifies one site of administration from a standardized list of possible sites."@en , "Une spécification de valeur catégorique qui spécifie le site d'administration."@fr ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:PDRO_0000052 a rdfs:Class ;
  rdfs:label "drug excipient specification"@en , "spécification d’excipient de médicament"@fr ;
  rdfs:comment "An information content entity that specifies an excipient of a drug product."@en , "Une entité de contenu informationnel qui spécifie un excipient d’un médicament prescrit."@fr ;
  rdfs:subClassOf obo:PDRO_0000009 .

obo:IAO_0000590 a rdfs:Class ;
  rdfs:label "written name"@en ;
  rdfs:comment "A textual entity that denotes a particular in reality."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PDRO_0000094 a rdfs:Class ;
  rdfs:label "site of drug administration specification"@en , "spécification de site d’administration de médicament"@fr ;
  rdfs:comment "An information content entity that specifies an anatomical entity which should be in contact with the drug product being administered during a dose administration."@en , "Une entité de contenu informationnel spécifiant une entité anatomique qui doit entrer en contact avec le médicament administré pendant une administration de dose."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000018 a rdfs:Class ;
  rdfs:label "zero-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:PDRO_0000102 a rdfs:Class ;
  rdfs:label "drug perfusion specification"@en , "spécification de taux de perfusion de médicament"@fr ;
  rdfs:comment "An action specification that instructs how the rate at which a dose is administered should be changed based on certain conditions in order to maintain a certain equilibrium or targeted effect."@en , "Une spécification d’action qui indique comment le taux auquel une dose est administrée doit être changé, sur la base de certaines conditions afin de maintenir un certain équilibre ou effet visé."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PDRO_0000108 a rdfs:Class ;
  rdfs:label "dose of drug product"@en , "dose de médicament"@fr ;
  rdfs:comment "The portion of a drug product that an organism is exposed to."@en , "Une portion de médicament à laquelle un organisme est exposé."@fr ;
  rdfs:subClassOf obo:PDRO_0000109 .

obo:PDRO_0000311 a rdfs:Class ;
  rdfs:label "ending validity temporal specification"@en , "spécification de fin de période de validité"@fr ;
  rdfs:comment "A textual entity that denotes the ending time of a validity period." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:DRON_00000028 a rdfs:Class ;
  rdfs:label "active ingredient"@en ;
  rdfs:comment "A role of a scattered molecular aggregate that is part of a drug product that is realized by (1) administration of the drug to an organism followed by (2) some change in the structure or functioning of some part of the organism."@en ;
  rdfs:subClassOf obo:DRON_00000030 .

obo:PDRO_0000038 a rdfs:Class ;
  rdfs:label "drug dose form item"@en , "élément d'information de forme médicamenteuse"@fr ;
  rdfs:comment "A drug product information item that is about a dose form of a drug product."@en , "Un élément d'information sur un médicament concernant sa forme (par exemple pilule orale, crème topique, liquide intraveineux, liquide oral)."@fr ;
  rdfs:subClassOf obo:PDRO_0000011 .

obo:OBI_0100051 a rdfs:Class ;
  rdfs:label "specimen"@en ;
  rdfs:comment "A material entity that has the specimen role."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:DRON_00000029 a rdfs:Class ;
  rdfs:label "excipient"@en ;
  rdfs:comment "A role of a scattered molecular aggregate in aiding the manufacture, prolonging the shelf life, or ensuring proper administration of a drug product."@en ;
  rdfs:subClassOf obo:DRON_00000030 .

obo:BFO_0000140 a rdfs:Class ;
  rdfs:label "continuant fiat boundary"@en ;
  rdfs:comment "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:PDRO_0000002 a rdfs:Class ;
  rdfs:label "prescriber identification"@en , "identification de prescripteur"@fr ;
  rdfs:comment "An author identification where the author is a particular health care provider and the document authored is a prescription."@en , "Une identification d'auteur où l'auteur est un fournisseur de soins particulier et le document en question est une prescription."@fr ;
  rdfs:subClassOf obo:IAO_0000590 .

obo:UO_0000002 a rdfs:Class ;
  rdfs:label "mass unit" ;
  rdfs:comment "\"A unit which is a standard measure of the amount of matter/energy of a physical object.\" [Wikipedia:Wikipedia]" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:PDRO_0000024 a rdfs:Class ;
  rdfs:label "drug prescription"@en , "prescription de médicaments"@fr ;
  rdfs:comment "A health care prescription specifying the initiation, modification or cessation of a drug administration."@en , "Une ordonnance indiquant une initiation, modification ou arrêt de l'administration de médicaments."@fr ;
  rdfs:subClassOf obo:PDRO_0000001 .

obo:PDRO_0010007 a rdfs:Class ;
  rdfs:label "drug prophylaxis"@en , "prophylaxie médicamenteuse"@fr ;
  rdfs:comment "A prophylaxis composed of one or more dose administrations."@en , "Une prophylaxie composée d'une ou plusieurs administrations de doses."@fr ;
  rdfs:subClassOf obo:OGMS_0000103 .

obo:PDRO_0000110 a rdfs:Class ;
  rdfs:label "supervising prescriber identification"@en , "identification de prescripteur superviseur"@fr ;
  rdfs:comment "A written name referring to a supervising prescriber."@en , "Un nom faisant référence à un prescripteur supervisant."@fr ;
  rdfs:subClassOf obo:PDRO_0000002 .

obo:PDRO_0000322 a rdfs:Class ;
  rdfs:label "drug prescription validity period"@en ;
  rdfs:subClassOf obo:BFO_0000038 .

obo:PDRO_0000090 a rdfs:Class ;
  rdfs:label "after some process condition"@en , "condition de fin de processus"@fr ;
  rdfs:comment "A condition that is true if and only if some process has ended."@en , "Une condition qui est vraie si et seulement si un certain processus est fini."@fr ;
  rdfs:subClassOf obo:PDRO_0000129 .

obo:BFO_0000031 a rdfs:Class ;
  rdfs:label "generically dependent continuant"@en ;
  rdfs:comment "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:IAO_0000579 a rdfs:Class ;
  rdfs:label "centrally registered identifier registry"@en ;
  rdfs:comment "A CRID registry is a dataset of CRID records, each consisting of a CRID symbol and additional information which was recorded in the dataset through a assigning a centrally registered identifier process."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:PDRO_0000196 a rdfs:Class ;
  rdfs:label "drug administration prescription item"@en ;
  rdfs:comment "A drug prescription item that specifies the administration of a drug. It gives pharmacists the permission to dispense a given drug product to a patient."@en ;
  rdfs:subClassOf obo:PDRO_0000195 .

obo:PDRO_0000150 a rdfs:Class ;
  rdfs:label "drug dispensing frequency specification"@en , "spécification de fréquence de distribution de médicament"@fr ;
  rdfs:comment "A value specification that specifies the frequency of a drug dispensing."@en , """Une spécification de valeur de fréquence indiquant la fréquence d'un processus de distribution de médicament.
Elle a une unité de la forme \"distribution de médicament par unité de temps\"."""@fr ;
  rdfs:subClassOf obo:PDRO_0010004 .

obo:BFO_0000147 a rdfs:Class ;
  rdfs:label "zero-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:BFO_0000144 a rdfs:Class ;
  rdfs:label "process profile"@en ;
  rdfs:comment "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:PDRO_0010045 a rdfs:Class ;
  rdfs:label "exactly some number of doses per unit time condition"@en , "condition indiquant que le nombre de doses par unité de temps est égal à"@fr ;
  rdfs:comment "A number of doses condition  that is true if and only if a specified number of dose administrations have occurred."@en , "une condition décrivant le nombre de doses par unité de temps comme étant égal à un certain nombre d'administration de doses."@fr ;
  rdfs:subClassOf obo:PDRO_0010042 .

obo:PDRO_0010029 a rdfs:Class ;
  rdfs:label "temporal duration specification"@en , "spécification de durée temporelle"@fr ;
  rdfs:comment "A scalar value specification that specifies a duration of time."@en , "Une spécification de valeur scalaire qui indique une durée de temps."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:PDRO_0010023 a rdfs:Class ;
  rdfs:label "drug product object count specification"@en , "spécification de nombre de médicaments"@fr ;
  rdfs:comment "A scalar value specification that specifies an amount of drug product objects."@en , "Une spécification de valeur scalaire qui indique un nombre de médicaments."@fr ;
  rdfs:subClassOf obo:OBI_0001931 .

obo:PDRO_0000068 a rdfs:Class ;
  rdfs:label "drug excipient item"@en , "élément d'information d'excipient médicamenteuse"@fr ;
  rdfs:comment "A drug product information item that is about one excipient in a drug product."@en , "Un élément d'information sur un médicament dénotant un de ses excipients."@fr ;
  rdfs:subClassOf obo:PDRO_0000011 .

obo:PDRO_0000030 a rdfs:Class ;
  rdfs:label "duration of administration specification"@en , "spécification de durée d'administration de dose"@fr ;
  rdfs:comment "An information content entity that specifies the duration during which a dose should be administered continuously."@en , "Une entité de contenu informationnel qui spécifie la durée pendant laquelle une dose doit être administrée de manière continue."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000005 a rdfs:Class ;
  rdfs:label "objective specification"@en ;
  rdfs:comment "a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0000659 a rdfs:Class ;
  rdfs:label "specimen collection process" ;
  rdfs:comment "A planned process with the objective of collecting a specimen." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:PDRO_0000006 a rdfs:Class ;
  rdfs:label "health care prescription time identification"@en , "identification du temps de création d'une prescription médicale"@fr ;
  rdfs:comment "A document creation time identification where the document is a prescription."@en , "Une identification de l'instant de création d'un document qui est une prescription médicale."@fr ;
  rdfs:subClassOf obo:PDRO_0000005 .

obo:PDRO_0000057 a rdfs:Class ;
  rdfs:label "current time is approximately some instant condition"@en , "condition affirmant que l'instant présent est approximativement un instant donné"@fr ;
  rdfs:comment "A condition which is true if and only if the current time is approximately some instant."@en , "Une condition qui est vraie si et seulement si l’instant présent est approximativement un instant donné."@fr ;
  rdfs:subClassOf obo:PDRO_0000072 .

obo:OBI_0000969 a rdfs:Class ;
  rdfs:label "dose specification" ;
  rdfs:comment "a directive information entity that describes the dose that will be administered to a target" ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0002076 a rdfs:Class ;
  rdfs:label "collection of specimens"@en ;
  rdfs:comment "A material entity that has two or more specimens as its parts."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:RO_0002351 a rdf:Property ;
  rdfs:label "has member"@en ;
  rdfs:comment "has member is a mereological relation between a collection and an item." ;
  rdfs:range obo:OBI_0100051 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:PDRO_0000129 a rdfs:Class ;
  rdfs:label "condition"@en , "condition"@fr ;
  rdfs:comment "An information content entity that describes some relationships between some entities and whose truthfullness is a prerequisite for something."@en , "Une entité de contenu informationnel qui décrit des relations entre certaines entités et dont la véracité est un prérequis pour quelque chose."@fr ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OGMS_0000090 a rdfs:Class ;
  rdfs:label "treatment" ;
  rdfs:comment "A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate the signs and symptoms of a disorder or pathological process"@en ;
  rdfs:subClassOf obo:COB_0000035 , obo:OBI_0000011 .

obo:IAO_0000310 a rdfs:Class ;
  rdfs:label "document"@en ;
  rdfs:comment "A collection of information content entities intended to be understood together as a whole"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:COB_0000035 a rdfs:Class ;
  rdfs:label "completely executed planned process"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OPMI_0000098 a rdfs:Class ;
  rdfs:label "person full name"@en ;
  rdfs:subClassOf obo:OPMI_0000094 .

obo:PDRO_9876002 a rdfs:Class ;
  rdfs:label "drug product dose form"@en , "forme de dose médicamenteuse"@fr ;
  rdfs:comment "The configuration of a drug product at the end of a pharmaceutical production process."@en , "La configuration d'un médicament à la fin d'un processus de production pharmaceutique."@fr ;
  rdfs:subClassOf obo:OGMS_0000039 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data entity"@en ;
  rdfs:comment "a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:DRON_00000030 a rdfs:Class ;
  rdfs:label "role of scattered molecular aggregate"@en ;
  rdfs:comment "A role borne by a scattered molecular aggregate and realized by its grains participating in one or more processes."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:BFO_0000024 a rdfs:Class ;
  rdfs:label "fiat object part"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

<http://protege.stanford.edu/plugins/owl/protege#defaultLanguage> a rdf:Property ;
  rdfs:range xsd:string .

obo:BFO_0000075 a rdf:Property ;
  rdfs:label "is aggregate of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000179 a rdf:Property ;
  rdfs:label "BFO OWL specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ;
  rdfs:range xsd:string .

obo:BFO_0000180 a rdf:Property ;
  rdfs:label "BFO CLIF specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ;
  rdfs:range xsd:string .

obo:IAO_0000111 a rdf:Property ;
  rdfs:label "editor preferred term"@en ;
  rdfs:range xsd:string .

obo:IAO_0000112 a rdf:Property ;
  rdfs:label "example of usage"@en ;
  rdfs:range xsd:string .

obo:IAO_0000114 a rdf:Property ;
  rdfs:label "has curation status"@en ;
  rdfs:range xsd:string .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "definition" ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "editor note"@en ;
  rdfs:range xsd:string .

obo:IAO_0000117 a rdf:Property ;
  rdfs:label "term editor"@en ;
  rdfs:range xsd:string .

obo:IAO_0000118 a rdf:Property ;
  rdfs:label "alternative term"@en ;
  rdfs:range xsd:string .

obo:IAO_0000119 a rdf:Property ;
  rdfs:label "definition source"@en ;
  rdfs:range xsd:string .

obo:IAO_0000142 a rdf:Property ;
  rdfs:label "mentions"@en ;
  rdfs:comment "An information artifact IA mentions an entity E exactly when it has a component/part that denotes E"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000231 a rdf:Property ;
  rdfs:range xsd:string .

obo:IAO_0000232 a rdf:Property ;
  rdfs:label "curator note"@en ;
  rdfs:range xsd:string .

obo:IAO_0000233 a rdf:Property ;
  rdfs:range xsd:string .

obo:IAO_0000234 a rdf:Property ;
  rdfs:range xsd:string .

obo:IAO_0000412 a rdf:Property ;
  rdfs:label "imported from"@en ;
  rdfs:range xsd:string .

obo:IAO_0000589 a rdf:Property ;
  rdfs:range xsd:string .

obo:IAO_0000600 a rdf:Property ;
  rdfs:label "elucidation"@en ;
  rdfs:range xsd:string .

obo:IAO_0000601 a rdf:Property ;
  rdfs:label "has associated axiom(nl)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000602 a rdf:Property ;
  rdfs:label "has associated axiom(fol)"@en ;
  rdfs:range xsd:string .

obo:IAO_0010000 a rdf:Property ;
  rdfs:label "has axiom label"@en ;
  rdfs:range xsd:string .

obo:OBI_0000295 a rdf:Property ;
  rdfs:label "is_specified_input_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:range obo:OBI_0000011 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:PDRO_0000133 a rdf:Property ;
  rdfs:label "has minimum range value"@en , "a valeur minimale de gamme"@fr ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:PDRO_0000134 a rdf:Property ;
  rdfs:label "has maximum range value"@en , "a valeur maximale de gamme"@fr ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000080 a rdf:Property ;
  rdfs:label "quality of"@en ;
  rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000081 a rdf:Property ;
  rdfs:label "role of"@en ;
  rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000086 a rdf:Property ;
  rdfs:label "has quality"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000019 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000092 a rdf:Property ;
  rdfs:label "disposition of"@en ;
  rdfs:comment "inverse of has disposition" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0001900 a rdf:Property ;
  rdfs:range xsd:string .

obo:RO_0002013 a rdf:Property ;
  rdfs:label "has regulatory component activity" ;
  rdfs:comment "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 , obo:RO_0002017 .

obo:RO_0002014 a rdf:Property ;
  rdfs:label "has negative regulatory component activity" ;
  rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002335 , obo:RO_0002013 .

obo:RO_0002015 a rdf:Property ;
  rdfs:label "has positive regulatory component activity" ;
  rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002336 , obo:RO_0002013 .

obo:RO_0002017 a rdf:Property ;
  rdfs:label "has component activity" ;
  rdfs:comment "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002018 .

obo:RO_0002022 a rdf:Property ;
  rdfs:label "directly regulated by" ;
  rdfs:comment "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002023 a rdf:Property ;
  rdfs:label "directly negatively regulated by" ;
  rdfs:comment "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002022 .

obo:RO_0002024 a rdf:Property ;
  rdfs:label "directly positively regulated by" ;
  rdfs:comment "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002022 .

obo:RO_0002025 a rdf:Property ;
  rdfs:label "has effector activity" ;
  rdfs:comment "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002017 .

obo:RO_0002086 a rdf:Property ;
  rdfs:label "ends after"@en ;
  rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002087 a rdf:Property ;
  rdfs:label "immediately preceded by"@en ;
  rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000062 .

obo:RO_0002090 a rdf:Property ;
  rdfs:label "immediately precedes"@en ;
  rdfs:comment "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000063 .

obo:RO_0002131 a rdf:Property ;
  rdfs:label "location of" ;
  rdfs:comment "x overlaps y if and only if there exists some z such that x has part z and z part of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0002180 a rdf:Property ;
  rdfs:label "has_component" ;
  rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002212 a rdf:Property ;
  rdfs:label "negatively regulates"@en ;
  rdfs:comment "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002305 , obo:RO_0002211 .

obo:RO_0002213 a rdf:Property ;
  rdfs:label "positively regulates"@en ;
  rdfs:comment "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002304 , obo:RO_0002211 .

obo:RO_0002216 a rdf:Property ;
  rdfs:label "capable of part of"@en ;
  rdfs:comment "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002500 , obo:RO_0002328 .

obo:RO_0002263 a rdf:Property ;
  rdfs:label "acts upstream of" ;
  rdfs:comment "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002264 .

obo:RO_0002264 a rdf:Property ;
  rdfs:label "acts upstream of or within" ;
  rdfs:comment "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002500 .

obo:RO_0002304 a rdf:Property ;
  rdfs:label "causally upstream of, positive effect" ;
  rdfs:comment "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004047 , obo:RO_0002411 .

obo:RO_0002305 a rdf:Property ;
  rdfs:label "causally upstream of, negative effect" ;
  rdfs:comment "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004046 , obo:RO_0002411 .

obo:RO_0002314 a rdf:Property ;
  rdfs:label "characteristic of part of"@en ;
  rdfs:comment "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002502 .

obo:RO_0002323 a rdf:Property ;
  rdfs:label "mereotopologically related to"@en ;
  rdfs:comment "A mereological relationship or a topological relationship" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002327 a rdf:Property ;
  rdfs:label "enables"@en ;
  rdfs:comment "c enables p iff c is capable of p and c acts to execute p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002215 .

obo:RO_0002328 a rdf:Property ;
  rdfs:label "functionally related to"@en ;
  rdfs:comment "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002331 a rdf:Property ;
  rdfs:label "involved in"@en ;
  rdfs:comment "c involved_in p if and only if c enables some process p', and p' is part of p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0000056 .

obo:RO_0002333 a rdf:Property ;
  rdfs:label "enabled by"@en ;
  rdfs:comment "inverse of enables" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000057 .

obo:RO_0002335 a rdf:Property ;
  rdfs:label "negatively regulated by"@en ;
  rdfs:comment "inverse of negatively regulates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002336 a rdf:Property ;
  rdfs:label "positively regulated by"@en ;
  rdfs:comment "inverse of positively regulates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002350 a rdf:Property ;
  rdfs:label "member of"@en ;
  rdfs:comment "is member of is a mereological relation between a item and a collection." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002352 a rdf:Property ;
  rdfs:label "input of"@en ;
  rdfs:comment "inverse of has input" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .

obo:RO_0002404 a rdf:Property ;
  rdfs:label "causally downstream of"@en ;
  rdfs:comment "inverse of upstream of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002427 , obo:BFO_0000062 .

obo:RO_0002405 a rdf:Property ;
  rdfs:label "immediately causally downstream of"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002404 , obo:RO_0002087 .

obo:RO_0002407 a rdf:Property ;
  rdfs:label "indirectly positively regulates"@en ;
  rdfs:comment "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002213 .

obo:RO_0002409 a rdf:Property ;
  rdfs:label "indirectly negatively regulates"@en ;
  rdfs:comment "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002212 .

obo:RO_0002410 a rdf:Property ;
  rdfs:label "causally related to"@en ;
  rdfs:comment "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002411 a rdf:Property ;
  rdfs:label "causally upstream of"@en ;
  rdfs:comment "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000063 .

obo:RO_0002412 a rdf:Property ;
  rdfs:label "immediately causally upstream of"@en ;
  rdfs:comment "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 , obo:RO_0002090 .

obo:RO_0002418 a rdf:Property ;
  rdfs:label "causally upstream of or within" ;
  rdfs:comment "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002427 a rdf:Property ;
  rdfs:label "causally downstream of or within" ;
  rdfs:comment "inverse of causally upstream of or within" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002428 a rdf:Property ;
  rdfs:label "involved in regulation of" ;
  rdfs:comment "c involved in regulation of p if c is involved in some p' and p' regulates some p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0002263 .

obo:RO_0002429 a rdf:Property ;
  rdfs:label "involved in positive regulation of" ;
  rdfs:comment "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002428 .

obo:RO_0002430 a rdf:Property ;
  rdfs:label "involved in negative regulation of" ;
  rdfs:comment "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002428 .

obo:RO_0002431 a rdf:Property ;
  rdfs:label "involved in or involved in regulation of" ;
  rdfs:comment "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0002500 , obo:RO_0002264 .

obo:RO_0002436 a rdf:Property ;
  rdfs:label "molecularly interacts with" ;
  rdfs:comment "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002434 .

obo:RO_0002447 a rdf:Property ;
  rdfs:label "phosphorylates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002436 .

obo:RO_0002464 a rdf:Property ;
  rdfs:label "helper property (not for use in curation)" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002481 a rdf:Property ;
  rdfs:label "is kinase activity" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002564 .

obo:RO_0002500 a rdf:Property ;
  rdfs:label "causal agent in process" ;
  rdfs:comment "A relationship between a material entity and a process where the material entity has some causal role that influences the process" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002595 .

obo:RO_0002502 a rdf:Property ;
  rdfs:label "depends on" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002559 a rdf:Property ;
  rdfs:label "causally influenced by" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002506 .

obo:RO_0002563 a rdf:Property ;
  rdfs:label "interaction relation helper property" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002464 .

obo:RO_0002564 a rdf:Property ;
  rdfs:label "molecular interaction relation helper property" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002563 .

obo:RO_0002578 a rdf:Property ;
  rdfs:label "directly regulates" ;
  rdfs:comment "p directly regulates q iff p is immediately causally upstream of q and p regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002412 , obo:RO_0002211 .

obo:RO_0002584 a rdf:Property ;
  rdfs:label "has part structure that is capable of" ;
  rdfs:comment "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002595 , obo:RO_0002328 .

obo:RO_0002596 a rdf:Property ;
  rdfs:label "capable of regulating" ;
  rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002500 .

obo:RO_0002597 a rdf:Property ;
  rdfs:label "capable of negatively regulating" ;
  rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002596 .

obo:RO_0002598 a rdf:Property ;
  rdfs:label "capable of positively regulating" ;
  rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002596 .

obo:RO_0002608 a rdf:Property ;
  rdfs:label "process has causal agent" ;
  rdfs:comment "Inverse of 'causal agent in process'" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0002629 a rdf:Property ;
  rdfs:label "directly positively regulates" ;
  rdfs:comment "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002213 .

obo:RO_0002630 a rdf:Property ;
  rdfs:label "directly negatively regulates" ;
  rdfs:comment "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002212 .

obo:RO_0004031 a rdf:Property ;
  rdfs:label "enables subfunction" ;
  rdfs:comment "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 .

obo:RO_0004032 a rdf:Property ;
  rdfs:label "acts upstream of or within, positive effect" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002264 .

obo:RO_0004033 a rdf:Property ;
  rdfs:label "acts upstream of or within, negative effect" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002264 .

obo:RO_0004034 a rdf:Property ;
  rdfs:label "acts upstream of, positive effect" ;
  rdfs:comment "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004032 , obo:RO_0002263 .

obo:RO_0004035 a rdf:Property ;
  rdfs:label "acts upstream of, negative effect" ;
  rdfs:comment "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004033 , obo:RO_0002263 .

obo:RO_0004046 a rdf:Property ;
  rdfs:label "causally upstream of or within, negative effect" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 .

obo:RO_0004047 a rdf:Property ;
  rdfs:label "causally upstream of or within, positive effect" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 .

obo:RO_0012011 a rdf:Property ;
  rdfs:label "indirectly causally upstream of"@en ;
  rdfs:comment "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0012012 a rdf:Property ;
  rdfs:label "indirectly regulates"@en ;
  rdfs:comment "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0012011 , obo:RO_0002211 .

obo:RO_0017001 a rdf:Property ;
  rdfs:label "device utilizes material"@en ;
  rdfs:comment "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0019001 a rdf:Property ;
  rdfs:label "positively regulates characteristic" ;
  rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0019000 .

obo:RO_0019002 a rdf:Property ;
  rdfs:label "negatively regulates characteristic" ;
  rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0019000 .

<http://xmlns.com/foaf/0.1/homepage> a rdf:Property ;
  rdfs:range xsd:string .

<http://www.w3.org/2002/07/owl#real> a rdfs:Datatype .

obo:IAO_0000078 a rdfs:Class ;
  rdfs:label "curation status specification"@en ;
  rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000002 a obo:IAO_0000078 ;
  rdfs:label "example to be eventually removed"@en .

obo:IAO_0000120 a obo:IAO_0000078 ;
  rdfs:label "metadata complete"@en ;
  rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en .

obo:IAO_0000121 a obo:IAO_0000078 ;
  rdfs:label "organizational term"@en ;
  rdfs:comment "The term was created to ease viewing/sorting terms for development purposes, but will not be included in a release."@en .

obo:IAO_0000122 a obo:IAO_0000078 ;
  rdfs:label "ready for release"@en ;
  rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en .

obo:IAO_0000123 a obo:IAO_0000078 ;
  rdfs:label "metadata incomplete"@en ;
  rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en .

obo:IAO_0000124 a obo:IAO_0000078 ;
  rdfs:label "uncurated"@en ;
  rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en .

obo:IAO_0000125 a obo:IAO_0000078 ;
  rdfs:label "pending final vetting"@en ;
  rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en .

obo:IAO_0000423 a obo:IAO_0000078 ;
  rdfs:label "to be replaced with external ontology term"@en ;
  rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en .

obo:IAO_0000428 a obo:IAO_0000078 ;
  rdfs:label "requires discussion"@en ;
  rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .

obo:IAO_0000225 a rdfs:Class ;
  rdfs:label "obsolescence reason specification"@en ;
  rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000103 a obo:IAO_0000225 ;
  rdfs:label "failed exploratory term"@en ;
  rdfs:comment "The term was initially used in an attempt to structure part of the ontology, but in retrospect failed to do a good job."@en .

obo:IAO_0000226 a obo:IAO_0000225 ;
  rdfs:label "placeholder removed"@en ;
  rdfs:comment "The term was created to temporarily stand in for a semantic purpose, but is no longer needed, typically due to another permanent term being defined."@en .

obo:IAO_0000227 a obo:IAO_0000225 ;
  rdfs:label "terms merged"@en ;
  rdfs:comment "The term has been combined with one or more other terms to create a more encompassing (merged) term."@en .

obo:IAO_0000228 a obo:IAO_0000225 ;
  rdfs:label "term imported"@en ;
  rdfs:comment "The term has been replaced by a term imported from another ontology."@en .

obo:IAO_0000229 a obo:IAO_0000225 ;
  rdfs:label "term split"@en ;
  rdfs:comment "The term has been split into two or more new terms."@en .

obo:OMO_0001000 a obo:IAO_0000225 ;
  rdfs:label "out of scope" ;
  rdfs:comment "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en .

obo:IAO_0000409 a rdfs:Class ;
  rdfs:label "denotator type"@en ;
  rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000410 a obo:IAO_0000409 ;
  rdfs:label "universal"@en .

obo:IAO_0000420 a obo:IAO_0000409 ;
  rdfs:label "defined class"@en ;
  rdfs:comment "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en .

obo:IAO_0000421 a obo:IAO_0000409 ;
  rdfs:label "named class expression"@en ;
  rdfs:comment "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en .
