PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:OHMI_0000907 a rdfs:Class ;
  rdfs:label "expansion of Fusobacteria in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Fusobacteria up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:BFO_0000062 a rdf:Property ;
  rdfs:label "preceded by"@en ;
  rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002086 .

obo:OHMI_0000467 a rdf:Property ;
  rdfs:label "has microbe population size altered in diseased host"@en ;
  rdfs:comment "A subproperty of the 'has participant' object property that has the domain of host-microbiome interaction and range of a microbe where the population of the microbe has size altered in a disease host organism" ;
  rdfs:domain obo:OHMI_0000001 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OHMI_0000423 a rdf:Property ;
  rdfs:label "has microbe expanded in diseased host"@en ;
  rdfs:comment "an object property that represents the relation between a host-microbiome interaction and a microbe where the population of the microbe is expanded in a diseased host compared to a healthy host control." ;
  rdfs:domain obo:OHMI_0000001 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:OHMI_0000467 .

obo:BFO_0000063 a rdf:Property ;
  rdfs:label "precedes"@en ;
  rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:label "part of"@en ;
  rdfs:comment "a core relation that holds between a part and its whole"@en ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections> , <http://ontologydesignpatterns.org/wiki/Submissions:PartOf> , <http://www.obofoundry.org/ro/#OBO_REL:part_of> , <https://wiki.geneontology.org/Part_of> ;
  rdfs:range obo:BFO_0000003 , obo:BFO_0000004 , obo:BFO_0000031 , obo:BFO_0000019 , obo:BFO_0000017 , obo:BFO_0000020 , obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002091 a rdf:Property ;
  rdfs:label "starts during"@en ;
  rdfs:comment "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:BFO_0000066 a rdf:Property ;
  rdfs:label "occurs in"@en ;
  rdfs:comment "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:seeAlso <https://wiki.geneontology.org/Occurs_in> ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000004 .

obo:RO_0002501 a rdf:Property ;
  rdfs:label "causal relation between processes" ;
  rdfs:comment "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:OHMI_0000377 a rdf:Property ;
  rdfs:label "has microbe depleted in diseased host"@en ;
  rdfs:comment "an object property that represents the relation between a host-microbiome interaction and a microbe where the population of the microbe is depleted in a diseased host compared to a healthy host control." ;
  rdfs:domain obo:OHMI_0000001 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:OHMI_0000467 .

obo:RO_0002233 a rdf:Property ;
  rdfs:label "has input"@en ;
  rdfs:comment "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Has_input> ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002211 a rdf:Property ;
  rdfs:label "regulates"@en ;
  rdfs:comment "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_HOM0000000 a rdf:Property ;
  rdfs:label "in similarity relationship with" ;
  rdfs:comment "Relation between biological objects that resemble or are related to each other sufficiently to warrant a comparison." ;
  rdfs:seeAlso obo:HOM_0000000 ;
  rdfs:range obo:BFO_0000003 , obo:BFO_0000002 .

obo:RO_0002018 a rdf:Property ;
  rdfs:label "has component process" ;
  rdfs:comment "w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002180 .

obo:BFO_0000055 a rdf:Property ;
  rdfs:label "realizes"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process"@en ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000017 .

obo:RO_0002214 a rdf:Property ;
  rdfs:label "has prototype"@en ;
  rdfs:comment "x has prototype y if and only if x is an instance of C and y is a prototypical instance of C. For example, every instance of heart, both normal and abnormal is related by the has prototype relation to some instance of a \"canonical\" heart, which participates in blood circulation." ;
  rdfs:range obo:BFO_0000015 , obo:BFO_0000002 .

obo:RO_0000057 a rdf:Property ;
  rdfs:label "has participant"@en ;
  rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 .

obo:RO_0002222 a rdf:Property ;
  rdfs:label "temporally related to"@en ;
  rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 .

obo:RO_0002334 a rdf:Property ;
  rdfs:label "regulated by"@en ;
  rdfs:comment "inverse of regulates" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002427 .

obo:RO_0002414 a rdf:Property ;
  rdfs:label "transitively provides input for"@en ;
  rdfs:comment "transitive form of directly_provides_input_for" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0004047 .

obo:OBI_0000094 a rdfs:Class ;
  rdfs:label "material processing"@en ;
  rdfs:comment "A planned process which results in physical changes in a specified input material"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000417 a rdf:Property ;
  rdfs:label "achieves_planned_objective" ;
  rdfs:comment "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:IAO_0000005 .

obo:OBI_0000299 a rdf:Property ;
  rdfs:label "has_specified_output"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000040 , obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OBI_0000293 a rdf:Property ;
  rdfs:label "has_specified_input"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000040 , obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OHMI_0000383 a rdfs:Class ;
  rdfs:label "depletion of L. rhamnosus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Lactobacillus rhamnosus is decreased." ;
  rdfs:subClassOf obo:OHMI_0000379 .

obo:OHMI_0000510 a rdfs:Class ;
  rdfs:label "expansion of Atopobium in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Atopobium up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OGG_0000000002 a rdfs:Class ;
  rdfs:label "gene"@en ;
  rdfs:comment "A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. " ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:RO_0003000 a rdf:Property ;
  rdfs:label "produces"@en ;
  rdfs:comment "a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 .

obo:RO_0001000 a rdf:Property ;
  rdfs:label "derives from"@en ;
  rdfs:comment "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000004 .

obo:RO_0000087 a rdf:Property ;
  rdfs:label "has role"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000023 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000085 a rdf:Property ;
  rdfs:label "has function"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000034 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000091 a rdf:Property ;
  rdfs:label "has disposition"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000016 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000056 a rdf:Property ;
  rdfs:label "participates in"@en ;
  rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 .

obo:RO_0002434 a rdf:Property ;
  rdfs:label "interacts with" ;
  rdfs:comment "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/interaction-relations/> ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 .

obo:RO_0001025 a rdf:Property ;
  rdfs:label "located in"@en ;
  rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
  rdfs:seeAlso <https://wiki.geneontology.org/Located_in> ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002437 a rdf:Property ;
  rdfs:label "biotically interacts with" ;
  rdfs:comment "An interaction relationship in which at least one of the partners is an organism and the other is either an organism or an abiotic entity with which the organism interacts." ;
  rdfs:seeAlso <http://dx.doi.org/10.1016/j.ecoinf.2014.08.005> , <http://eol.org/schema/terms/interactsWith> ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002434 , obo:RO_0002321 .

obo:RO_0003001 a rdf:Property ;
  rdfs:label "produced by"@en ;
  rdfs:comment "a produced_by b iff some process that occurs_in b has_output a." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 .

obo:OHMI_0000865 a rdfs:Class ;
  rdfs:label "depletion of Ruminococcus in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Ruminococcus down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_1234680 a rdfs:Class ;
  rdfs:label "Streptococcus rubneri" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:RO_0002574 a rdf:Property ;
  rdfs:label "participates in a biotic-biotic interaction with" ;
  rdfs:seeAlso <http://dx.doi.org/10.1016/j.ecoinf.2014.08.005> ;
  rdfs:domain obo:COB_0000022 ;
  rdfs:range obo:COB_0000022 ;
  rdfs:subPropertyOf obo:RO_0002437 .

obo:RO_0020105 a rdf:Property ;
  rdfs:label "is anatomical entity" ;
  rdfs:comment "This property only applies to anatomical entities." ;
  rdfs:domain obo:UBERON_0001062 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002200 a rdf:Property ;
  rdfs:label "has phenotype"@en ;
  rdfs:comment "A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype)." ;
  rdfs:range obo:UPHENO_0001001 ;
  rdfs:subPropertyOf obo:RO_0016001 .

obo:RO_0000086 a rdf:Property ;
  rdfs:label "has quality"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000019 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:OHMI_0000265 a rdfs:Class ;
  rdfs:label "depletion of Prevotellaceae in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an decrease of Prevotellaceae in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000255 .

obo:OBI_0001331 a rdfs:Class ;
  rdfs:label "transcription profiling identification objective"@en ;
  rdfs:comment "A molecular feature identification objective that aims to characterize the abundance of transcripts"@en ;
  rdfs:subClassOf obo:OBI_0000131 .

obo:OBI_0001938 a rdf:Property ;
  rdfs:label "has value specification" ;
  rdfs:comment "A relation between an information content entity and a value specification that specifies its value." ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range obo:OBI_0001933 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000136 a rdf:Property ;
  rdfs:label "is about"@en ;
  rdfs:comment "is_about is a (currently) primitive relation that relates an information artifact to an entity."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0000833 a rdf:Property ;
  rdfs:label "objective_achieved_by" ;
  rdfs:comment "This relation obtains between a a objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:domain obo:IAO_0000005 ;
  rdfs:range obo:OBI_0000011 .

obo:RO_0000058 a rdf:Property ;
  rdfs:label "is concretized as"@en ;
  rdfs:comment "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants."@en ;
  rdfs:domain obo:BFO_0000031 ;
  rdfs:range obo:BFO_0000020 .

obo:OHMI_0000785 a rdfs:Class ;
  rdfs:label "depletion of Blautia obeum in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Blautia obeum down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000224 a rdfs:Class ;
  rdfs:label "expansion of Rikenellaceae in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of Rikenellaceae in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000099 .

obo:NCBITaxon_1591 a rdfs:Class ;
  rdfs:label "Lactobacillus sp." ;
  rdfs:subClassOf obo:NCBITaxon_1578 .

obo:OHMI_0000059 a rdf:Property ;
  rdfs:label "microbe susceptibly expanded in gut of human with disease"@en ;
  rdfs:comment "An object property that represents the susceptible increase (compared to healthy control) of the population of a microbe in the gut of a human with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000056 .

obo:PCO_0000019 a rdfs:Class ;
  rdfs:label "community species diversity"@en ;
  rdfs:comment "The number of different species that are represented in a given community, weighted by their abundance. Community species diversity can be calculated in different ways, but consists of two components: species richness and species evenness."@en ;
  rdfs:subClassOf obo:PCO_0000004 .

obo:RO_0000059 a rdf:Property ;
  rdfs:label "concretizes"@en ;
  rdfs:comment "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ;
  rdfs:domain obo:BFO_0000020 ;
  rdfs:range obo:BFO_0000031 .

obo:OHMI_0000235 a rdfs:Class ;
  rdfs:label "depletion of Pseudomonas sp. in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity microbiome interaction that shows an decrease of Pseudomonas sp. in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:NCBITaxon_117571 a rdfs:Class ;
  rdfs:label "Euteleostomi" ;
  rdfs:subClassOf obo:NCBITaxon_7742 .

obo:NCBITaxon_140626 a rdfs:Class ;
  rdfs:label "Lachnobacterium bovis" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000774 a rdfs:Class ;
  rdfs:label "expansion of Verrucomicrobia in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Verrucomicrobia up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_2767887 a rdfs:Class ;
  rdfs:label "Ligilactobacillus" ;
  rdfs:subClassOf obo:NCBITaxon_33958 .

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:BFO_0000054 a rdf:Property ;
  rdfs:label "realized in"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000017 ;
  rdfs:range obo:BFO_0000015 , obo:OBI_1110021 , obo:OBI_0000070 .

obo:RO_0000079 a rdf:Property ;
  rdfs:label "function of"@en ;
  rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000034 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:OHMI_0000097 a rdfs:Class ;
  rdfs:label "depletion of Clostridiales in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity microbiome interaction that shows an decrease of Clostridiales in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:OHMI_0000254 a rdfs:Class ;
  rdfs:label "expansion of Desulfovibrionaceae in arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Desulfovibrionaceae in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:OHMI_0000522 a rdfs:Class ;
  rdfs:label "expansion of Aerococcaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Aerococcaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_186822 a rdfs:Class ;
  rdfs:label "Paenibacillaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1385 .

obo:NCBITaxon_315405 a rdfs:Class ;
  rdfs:label "Streptococcus gallolyticus" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity"@en ;
  rdfs:comment "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:UBERON_0001988 a rdfs:Class ;
  rdfs:label "feces" ;
  rdfs:comment "Portion of semisolid bodily waste discharged through the anus[MW,modified]" ;
  rdfs:subClassOf obo:UBERON_0000174 .

obo:OHMI_0000041 a rdfs:Class ;
  rdfs:label "depletion of Sutterella wadsworthensis in RA human gut"@en ;
  rdfs:comment "RA human-gut microbiome interaction that shows an decrease of Sutterella wadsworthensis in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000897 a rdfs:Class ;
  rdfs:label "expansion of Olsenella in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Olsenella up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000006 a rdfs:Class ;
  rdfs:label "fungal microbiome"@en ;
  rdfs:comment "A microbiome that includes a collective population of fungal microorganisms." ;
  rdfs:subClassOf obo:OHMI_0000003 .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has part"@en ;
  rdfs:comment "a core relation that holds between a whole and its part"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:NCBITaxon_207244 a rdfs:Class ;
  rdfs:label "Anaerostipes" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000521 a rdfs:Class ;
  rdfs:label "expansion of Streptococcus in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Streptococcus up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:UBERON_0000465 a rdfs:Class ;
  rdfs:label "material anatomical entity" ;
  rdfs:comment "Anatomical entity that has mass." ;
  rdfs:subClassOf obo:UBERON_0001062 .

obo:NCBITaxon_1769710 a rdfs:Class ;
  rdfs:label "Sellimonas" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_71275 a rdfs:Class ;
  rdfs:label "rosids" ;
  rdfs:subClassOf obo:NCBITaxon_1437201 .

obo:OHMI_0000854 a rdfs:Class ;
  rdfs:label "expansion of Porphyromonadaceae in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Porphyromonadaceae up-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:OHMI_0000092 a rdfs:Class ;
  rdfs:label "depletion of Haemophilus spp. in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity microbiome interaction that shows an decrease of Haemophilus sp  in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000084 .

obo:NCBITaxon_1064535 a rdfs:Class ;
  rdfs:label "Megasphaera elsdenii DSM 20460" ;
  rdfs:subClassOf obo:NCBITaxon_906 .

obo:NCBITaxon_644652 a rdfs:Class ;
  rdfs:label "Gordonibacter" ;
  rdfs:subClassOf obo:NCBITaxon_1643826 .

obo:OHMI_0000809 a rdfs:Class ;
  rdfs:label "depletion of Enterobacter in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Enterobacter down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000414 a rdfs:Class ;
  rdfs:label "expansion of H. pylori in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Helicobacter pylori is increased." ;
  rdfs:subClassOf obo:OHMI_0000411 .

obo:NCBITaxon_39491 a rdfs:Class ;
  rdfs:label "Agathobacter rectalis" ;
  rdfs:subClassOf obo:NCBITaxon_1766253 .

obo:OHMI_0000030 a rdfs:Class ;
  rdfs:label "patient with RA having decreased gut microbial diversity"@en ;
  rdfs:comment "An association of human gut microbiota with rheumatoid arthritis (RA) that shows a patient with RV  exhibits decreased gut microbial diversity" ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000198 a rdfs:Class ;
  rdfs:label "expansion of Lachnospiraceae in SLE  mouse gut"@en ;
  rdfs:comment "An association of musculus gut microbiota with system lupus erythematosus(SLE) that shows an expansion of Lachnospiraceae in musculus with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000197 .

obo:IAO_0000009 a rdfs:Class ;
  rdfs:label "datum label"@en ;
  rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OHMI_0000860 a rdfs:Class ;
  rdfs:label "depletion of Bacteroides fragilis in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Bacteroides fragilis down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000430 a rdfs:Class ;
  rdfs:label "depletion of Subdoligranulum sp. 60_17 in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Subdoligranulum sp. 60_17 is decreased." ;
  rdfs:subClassOf obo:OHMI_0000378 .

obo:OHMI_0000667 a rdfs:Class ;
  rdfs:label "COPD stable"@en ;
  rdfs:comment "A process quality in which the CODP disease is in its stable stage." ;
  rdfs:subClassOf obo:OHMI_0000665 .

obo:DOID_0080355 a rdfs:Class ;
  rdfs:label "hepatobiliary system cancer"@en ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the hepatobiliary system" ;
  rdfs:subClassOf obo:DOID_3119 .

obo:OHMI_0000306 a rdf:Property ;
  rdfs:label "disease in host with susceptibly expanded microbe"@en ;
  rdfs:comment "An object property that represents a disease in a host where the host has susceptibly increased population of a microbe. This is a shortcut relation where the domain is disease, and the range is a microbe." ;
  rdfs:domain obo:DOID_4 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OHMI_0000339 a rdf:Property ;
  rdfs:label "disease in host with susceptibly depleted microbe"@en ;
  rdfs:comment "An object property that represents a disease in a host where the host has susceptibly decreased population of a microbe. This is a shortcut relation where the domain is disease, and the range is a microbe." ;
  rdfs:domain obo:DOID_4 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:NCBITaxon_156973 a rdfs:Class ;
  rdfs:label "Dysgonomonas" ;
  rdfs:subClassOf obo:NCBITaxon_171549 .

obo:OHMI_0000470 a rdfs:Class ;
  rdfs:label "microbial genome"@en ;
  rdfs:comment "A genome from a microbe" ;
  rdfs:subClassOf obo:OGG_0000000001 .

obo:OHMI_0000455 a rdfs:Class ;
  rdfs:label "expansion of F. nucleatum subsp. polymorphum in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacterium nucleatum subsp. polymorphum is increased." ;
  rdfs:subClassOf obo:OHMI_0000289 .

obo:DOID_13189 a rdfs:Class ;
  rdfs:label "gout" ;
  rdfs:comment "An arthritis that has_material_basis_in uric acid crystal deposits located_in joint." ;
  rdfs:subClassOf obo:DOID_848 .

obo:OBI_1110093 a rdfs:Class ;
  rdfs:label "disposition to infect an organism"@en ;
  rdfs:comment "Is a role borne by an agent, and realized when in contact with or inside another organism in which it is capable of replicating and causing disease"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:OHMI_0000532 a rdfs:Class ;
  rdfs:label "expansion of Centipeda in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Centipeda up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000118 a rdfs:Class ;
  rdfs:label "expansion of Porphyromonadaceae in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Porphyromonadaceae in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000117 .

obo:OHMI_0000917 a rdfs:Class ;
  rdfs:label "expansion of Akkermansia in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Akkermansia up-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000213 a rdfs:Class ;
  rdfs:label "depletion of Clostridiales in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an decrease of Clostridiales in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000212 .

obo:NCBITaxon_165779 a rdfs:Class ;
  rdfs:label "Anaerococcus" ;
  rdfs:subClassOf obo:NCBITaxon_1570339 .

obo:OHMI_0000246 a rdfs:Class ;
  rdfs:label "expansion of Anaerolineae in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Anaerolineae in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000245 .

obo:OHMI_0000372 a rdfs:Class ;
  rdfs:label "expansion of Porphyromonas in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Porphyromonas is increased." ;
  rdfs:subClassOf obo:OHMI_0000305 .

obo:NCBITaxon_52228 a rdfs:Class ;
  rdfs:label "Hallella" ;
  rdfs:subClassOf obo:NCBITaxon_171552 .

obo:OHMI_0000441 a rdfs:Class ;
  rdfs:label "expansion of B.obeum in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Blautia obeum is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:OHMI_0000208 a rdfs:Class ;
  rdfs:label "expansion of Alistipes in SLE  mouse gut"@en ;
  rdfs:comment "An association of musculus gut microbiota with system lupus erythematosus(SLE) that shows an expansion of Alistipes in musculus with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000197 .

obo:OHMI_0000243 a rdfs:Class ;
  rdfs:label "expansion of Selenomonas in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity  microbiome interaction that shows an expansion of Selenomonas in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:OHMI_0000511 a rdfs:Class ;
  rdfs:label "expansion of Cryptobacterium in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Cryptobacterium up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000466 a rdfs:Class ;
  rdfs:label "microbial species diversity"@en ;
  rdfs:comment "A community species diversity that exists in a microbiome ecosystem where different microbial species are found." ;
  rdfs:subClassOf obo:PCO_0000019 .

obo:OHMI_0000879 a rdfs:Class ;
  rdfs:label "depletion of Lachnospiraceae in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Lachnospiraceae down-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_128827 a rdfs:Class ;
  rdfs:label "Erysipelotrichaceae" ;
  rdfs:subClassOf obo:NCBITaxon_526525 .

obo:IAO_8000014 a rdfs:Class ;
  rdfs:label "generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OHMI_0000816 a rdfs:Class ;
  rdfs:label "depletion of Barnesiella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Barnesiella down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000115 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidetes in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of rare taxa,Bacteroidetes in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:OHMI_0000079 a rdfs:Class ;
  rdfs:label "depletion of Porphyromonas in RA human respiratory airway"@en ;
  rdfs:comment "RA human respiratory airway microbiome interaction that shows an decrease of Porphyromonas in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000078 .

obo:OBI_0000880 a rdfs:Class ;
  rdfs:label "RNA extract" ;
  rdfs:comment "an extract which is the output of an extraction process in which RNA molecules are isolated from a specimen." ;
  rdfs:subClassOf obo:OBI_0001010 .

obo:OBI_0000312 a rdf:Property ;
  rdfs:label "is_specified_output_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:OBI_0000011 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:OBI_0000643 a rdf:Property ;
  rdfs:label "has grain" ;
  rdfs:comment "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car." ;
  rdfs:range <https://w3id.org/linkml/Any> , obo:CL_0000010 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:NCBITaxon_912 a rdfs:Class ;
  rdfs:label "Nitrobacter hamburgensis" ;
  rdfs:subClassOf obo:NCBITaxon_356 .

obo:NCBITaxon_813 a rdfs:Class ;
  rdfs:label "Chlamydia trachomatis"@en ;
  rdfs:subClassOf obo:NCBITaxon_810 .

obo:OBI_0000832 a rdfs:Class ;
  rdfs:label "measurement device" ;
  rdfs:comment "A device in which a measure function inheres." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:IAO_0000416 a rdfs:Class ;
  rdfs:label "time measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measuring a temporal interval"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_0000413 a rdf:Property ;
  rdfs:label "is duration of"@en ;
  rdfs:comment "relates a process to a time-measurement-datum that represents the duration of the process"@en ;
  rdfs:domain obo:IAO_0000416 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000039 a rdf:Property ;
  rdfs:label "has measurement unit label"@en ;
  rdfs:range obo:UO_0000003 , obo:IAO_0000003 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000004 a rdf:Property ;
  rdfs:label "has measurement value"@en ;
  rdfs:domain obo:IAO_0000032 ;
  rdfs:range xsd:double .

obo:NCBITaxon_86331 a rdfs:Class ;
  rdfs:label "Mogibacterium" ;
  rdfs:subClassOf obo:NCBITaxon_543314 .

obo:NCBITaxon_4932 a rdfs:Class ;
  rdfs:label "Saccharomyces cerevisiae" ;
  rdfs:subClassOf obo:NCBITaxon_4892 .

obo:NCBITaxon_102106 a rdfs:Class ;
  rdfs:label "Collinsella" ;
  rdfs:subClassOf obo:NCBITaxon_84107 .

obo:NCBITaxon_289201 a rdfs:Class ;
  rdfs:label "Pontibacillus" ;
  rdfs:subClassOf obo:NCBITaxon_186817 .

obo:NCBITaxon_119045 a rdfs:Class ;
  rdfs:label "Methylobacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_356 .

obo:OBI_0001933 a rdfs:Class ;
  rdfs:label "value specification" ;
  rdfs:comment "An information content entity that specifies a value within a classification scheme or on a quantitative scale." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002135 a rdf:Property ;
  rdfs:label "has specified value"@en ;
  rdfs:comment "A relation between a value specification and a literal." ;
  rdfs:domain obo:OBI_0001933 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0001937 a rdf:Property ;
  rdfs:label "has specified numeric value" ;
  rdfs:comment "A relation between a value specification and a number that quantifies it." ;
  rdfs:domain obo:OBI_0001933 ;
  rdfs:range <http://www.w3.org/2002/07/owl#real> ;
  rdfs:subPropertyOf obo:OBI_0002135 .

obo:NCBITaxon_76859 a rdfs:Class ;
  rdfs:label "Fusobacterium animalis" ;
  rdfs:subClassOf obo:NCBITaxon_848 .

obo:OHMI_0000560 a rdfs:Class ;
  rdfs:label "expansion of Tannerella in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Tannerella up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_6239 a rdfs:Class ;
  rdfs:label "Caenorhabditis elegans" ;
  rdfs:subClassOf obo:NCBITaxon_1206794 .

obo:OHMI_0000928 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacterium in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Faecalibacterium down-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:NCBITaxon_946234 a rdfs:Class ;
  rdfs:label "Flavonifractor" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:OHMI_0000249 a rdfs:Class ;
  rdfs:label "expansion of Corynebacteriales in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Corynebacteriales in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:OHMI_0000107 a rdfs:Class ;
  rdfs:label "expansion of Klebsiella pneumoniae in AS human oral cavity"@en ;
  rdfs:comment "an AS human oral cavity  microbiome interaction that shows an expansion of Klebsiella pneumoniae in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000106 .

obo:OHMI_0000066 a rdfs:Class ;
  rdfs:label "expansion of Collinsella aerofaciens in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Collinsella aerofaciens in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000085 .

obo:OHMI_0000425 a rdfs:Class ;
  rdfs:label "depletion of Bacteroides fragilis in RA human gut compared to fibromyalgia patients"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Bacteroides fragilis in patients with RA compared with fibromyalgia patients." ;
  rdfs:subClassOf obo:OHMI_0000418 .

obo:OHMI_0000023 a rdfs:Class ;
  rdfs:label "human gut microbiome interaction in Crohn's disease"@en ;
  rdfs:comment "A human-gut microbiome interaction that is associated with Crohn's disease." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:NCBITaxon_216816 a rdfs:Class ;
  rdfs:label "Bifidobacterium longum" ;
  rdfs:subClassOf obo:NCBITaxon_1678 .

obo:NCBITaxon_147537 a rdfs:Class ;
  rdfs:label "Saccharomycotina" ;
  rdfs:subClassOf obo:NCBITaxon_716545 .

obo:UBERON_0000167 a rdfs:Class ;
  rdfs:label "oral cavity" ;
  rdfs:comment "Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present)" ;
  rdfs:subClassOf obo:UBERON_0001062 .

obo:NCBITaxon_34104 a rdfs:Class ;
  rdfs:label "Streptobacillus" ;
  rdfs:subClassOf obo:NCBITaxon_1129771 .

obo:NCBITaxon_28131 a rdfs:Class ;
  rdfs:label "Prevotella intermedia" ;
  rdfs:subClassOf obo:NCBITaxon_838 .

obo:OHMI_0000350 a rdf:Property ;
  rdfs:label "microbe susceptibly expanded in oral cavity of human with disease"@en ;
  rdfs:comment "An object property that represents the susceptible increase (compared to healthy control) of the population of a microbe in the oral cavity of a human with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000056 .

obo:OHMI_0000272 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted in gut of human with disease"@en ;
  rdfs:comment "An object property that represents the susceptible decrease (compared to healthy control) of the population of a microbe in the gut of a human with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000232 .

obo:OHMI_0000304 a rdf:Property ;
  rdfs:label "microbe susceptibly expanded in gut of rat with disease"@en ;
  rdfs:comment "An object property that represents the susceptible increase (compared to healthy control) of the population of a microbe in the gut of a rat with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000301 .

obo:OHMI_0000347 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted in respiratory airway of human with disease"@en ;
  rdfs:comment "An object property that represents the susceptible decrease (compared to healthy control) of the population of a microbe in the respiratory airway of a human with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000232 .

obo:OHMI_0000696 a rdfs:Class ;
  rdfs:label "expansion of Flavonifractor plautii ATCC29863 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Flavonifractor plautii ATCC29863 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000656 a rdfs:Class ;
  rdfs:label "depletion of Parabacteroides goldsteinii in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Parabacteroides goldsteinii down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:NCBITaxon_1685 a rdfs:Class ;
  rdfs:label "Bifidobacterium breve" ;
  rdfs:subClassOf obo:NCBITaxon_1678 .

obo:IAO_8000003 a rdfs:Class ;
  rdfs:label "main release ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be the primary release product and the one consumed by the majority of tools."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:NCBITaxon_165179 a rdfs:Class ;
  rdfs:label "Segatella copri" ;
  rdfs:subClassOf obo:NCBITaxon_2974251 .

obo:OHMI_0000359 a rdf:Property ;
  rdfs:label "microbe susceptibly expanded in gut of mouse with disease"@en ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000358 .

obo:OHMI_0000501 a rdfs:Class ;
  rdfs:label "expansion of Haemophilus in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Haemophilus up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000293 a rdfs:Class ;
  rdfs:label "expansion of Filifactor in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Filifactor is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:OBI_0001573 a rdfs:Class ;
  rdfs:label "DNA sequence data" ;
  rdfs:comment "A sequence data item that is about the primary structure of DNA" ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:NCBITaxon_846 a rdfs:Class ;
  rdfs:label "Oxalobacter" ;
  rdfs:subClassOf obo:NCBITaxon_80840 .

obo:OHMI_0000789 a rdfs:Class ;
  rdfs:label "depletion of Phocaeicola coprocola in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Phocaeicola coprocola down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000045 a rdfs:Class ;
  rdfs:label "expansion of Eggerthella lenta in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Eggerthella lenta in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000222 .

obo:OHMI_0000280 a rdfs:Class ;
  rdfs:label "reactive arthritis rat-gut microbiome interaction"@en ;
  rdfs:comment "A rattus gut-microbiome interaction that is associated with reactive arthritis'." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:OHMI_0000260 a rdfs:Class ;
  rdfs:label "expansion of Enterococcus in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Enterococcus in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000258 .

obo:COB_0000022 a rdfs:Class ;
  rdfs:label "organism"@en ;
  rdfs:comment "A material entity that is a maximal functionally integrated unit that develops from a program encoded in a genome"@en ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:NCBITaxon_1382 a rdfs:Class ;
  rdfs:label "Lancefieldella parvula" ;
  rdfs:subClassOf obo:NCBITaxon_1643824 .

obo:NCBITaxon_497 a rdfs:Class ;
  rdfs:label "Psychrobacter" ;
  rdfs:subClassOf obo:NCBITaxon_468 .

obo:NCBITaxon_629 a rdfs:Class ;
  rdfs:label "Yersinia"@en ;
  rdfs:subClassOf obo:NCBITaxon_1903411 .

obo:OHMI_0000469 a rdfs:Class ;
  rdfs:label "relative abundance of microbe in host"@en ;
  rdfs:comment "A relative species abundance that refers to the microbial species abundance in a host ecosystem" ;
  rdfs:subClassOf obo:OHMI_0000468 .

obo:NCBITaxon_661182 a rdfs:Class ;
  rdfs:label "Perlucidibaca" ;
  rdfs:subClassOf obo:NCBITaxon_72274 .

obo:OHMI_0000178 a rdfs:Class ;
  rdfs:label "expansion of Prevotella in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of Prevotella in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:OHMI_0000034 a rdfs:Class ;
  rdfs:label "depletion of Klebsiella pneumoniae in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Klebsiella pneumoniae in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:NCBITaxon_548 a rdfs:Class ;
  rdfs:label "Klebsiella aerogenes" ;
  rdfs:subClassOf obo:NCBITaxon_570 .

obo:NCBITaxon_727 a rdfs:Class ;
  rdfs:label "Haemophilus influenzae" ;
  rdfs:subClassOf obo:NCBITaxon_724 .

obo:OHMI_0000354 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted in oral cavity of human with disease"@en ;
  rdfs:comment "An object property that represents the susceptible decrease (compared to healthy control) of the population of a microbe in the oral cavity of a human with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000232 .

obo:OHMI_0000678 a rdfs:Class ;
  rdfs:label "expansion of Acinetobacter sp. in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Acinetobacter sp. up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000683 a rdfs:Class ;
  rdfs:label "expansion of Trueperella pyogenes in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Trueperella pyogenes up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000279 a rdfs:Class ;
  rdfs:label "expansion of Yersinia in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Yersinia in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000255 .

obo:OHMI_0000639 a rdfs:Class ;
  rdfs:label "expansion of Haemophilus in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Haemophilus up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000790 a rdfs:Class ;
  rdfs:label "depletion of Blautia wexlerae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Blautia wexlerae down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_693746 a rdfs:Class ;
  rdfs:label "Oscillibacter valericigenes Sjm18-20" ;
  rdfs:subClassOf obo:NCBITaxon_459786 .

obo:NCBITaxon_49546 a rdfs:Class ;
  rdfs:label "Flavobacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_976 .

obo:HP_0000118 a rdfs:Class ;
  rdfs:label "Phenotypic abnormality" ;
  rdfs:comment "A phenotypic abnormality." ;
  rdfs:subClassOf obo:UPHENO_0001002 .

obo:OHMI_0000633 a rdfs:Class ;
  rdfs:label "depletion of Proteobacteria in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Proteobacteria down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:NCBITaxon_358742 a rdfs:Class ;
  rdfs:label "Enterocloster aldenensis" ;
  rdfs:subClassOf obo:NCBITaxon_2719313 .

obo:OHMI_0000458 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides sp. in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Bacteroides sp in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000051 .

obo:NCBITaxon_1723384 a rdfs:Class ;
  rdfs:label "Fenollaria timonensis" ;
  rdfs:subClassOf obo:NCBITaxon_1686313 .

obo:NCBITaxon_1716 a rdfs:Class ;
  rdfs:label "Corynebacterium" ;
  rdfs:subClassOf obo:NCBITaxon_1653 .

obo:OHMI_0000200 a rdfs:Class ;
  rdfs:label "expansion of Clostridiales in SLE  mouse gut"@en ;
  rdfs:comment "An association of musculus gut microbiota with system lupus erythematosus(SLE) that shows an expansion of Clostridiales in musculus with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000197 .

obo:NCBITaxon_95818 a rdfs:Class ;
  rdfs:label "Candidatus Saccharimonadota" ;
  rdfs:subClassOf obo:NCBITaxon_2 .

obo:OHMI_0000629 a rdfs:Class ;
  rdfs:label "depletion of Eikenella in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Eikenella down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:DOID_6196 a rdfs:Class ;
  rdfs:label "reactive arthritis"@en ;
  rdfs:comment "An arthritis that is an autoimmune disease which develops due to an infection located elsewhere in the body. [database_cross_reference: url:http://emedicine.medscape.com/article/331347-overview][database_cross_reference: url:http://en.wikipedia.org/wiki/Reactive_arthritis]" ;
  rdfs:subClassOf obo:DOID_848 .

obo:NCBITaxon_1579 a rdfs:Class ;
  rdfs:label "Lactobacillus acidophilus" ;
  rdfs:subClassOf obo:NCBITaxon_1578 .

obo:OHMI_0000748 a rdfs:Class ;
  rdfs:label "expansion of Leptonema in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Leptonema up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000499 a rdfs:Class ;
  rdfs:label "bacterial change in lung of exacerbation COPD patient compared to stable COPD"@en ;
  rdfs:comment "COPD human respiratory airway  microbiome interaction that shows an change of bacteria in patients with exacerbation COPD compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000489 .

obo:NCBITaxon_1905344 a rdfs:Class ;
  rdfs:label "Ruthenibacterium" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:NCBITaxon_150120 a rdfs:Class ;
  rdfs:label "Shewanella livingstonensis" ;
  rdfs:subClassOf obo:NCBITaxon_135622 .

obo:NCBITaxon_1206794 a rdfs:Class ;
  rdfs:label "Ecdysozoa" ;
  rdfs:subClassOf obo:NCBITaxon_33213 .

obo:NCBITaxon_1357 a rdfs:Class ;
  rdfs:label "Lactococcus" ;
  rdfs:subClassOf obo:NCBITaxon_1300 .

obo:OHMI_0000395 a rdfs:Class ;
  rdfs:label "expansion of Escherichia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Escherichia is increased." ;
  rdfs:subClassOf obo:OHMI_0000349 .

obo:NCBITaxon_314146 a rdfs:Class ;
  rdfs:label "Euarchontoglires" ;
  rdfs:subClassOf obo:NCBITaxon_40674 .

obo:OHMI_0000142 a rdfs:Class ;
  rdfs:label "depletion of Coprococcus catus in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Coprococcus catus in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000127 .

obo:DOID_4606 a rdfs:Class ;
  rdfs:label "bile duct cancer" ;
  rdfs:comment "A biliary tract cancer that is located_in the bile duct." ;
  rdfs:subClassOf obo:DOID_0080355 , obo:DOID_3118 .

obo:OHMI_0000537 a rdfs:Class ;
  rdfs:label "expansion of Eubacteriaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Eubacteriaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000778 a rdfs:Class ;
  rdfs:label "depletion of Enterocloster clostridioformis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Enterocloster clostridioformis down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000578 a rdfs:Class ;
  rdfs:label "depletion of Clostridium  in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Clostridium  down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_86731 a rdfs:Class ;
  rdfs:label "Magnolia globosa" ;
  rdfs:subClassOf obo:NCBITaxon_1437183 .

obo:NCBITaxon_1776391 a rdfs:Class ;
  rdfs:label "Romboutsia timonensis" ;
  rdfs:subClassOf obo:NCBITaxon_186804 .

obo:NCBITaxon_87265 a rdfs:Class ;
  rdfs:label "Umbilicariaceae" ;
  rdfs:subClassOf obo:NCBITaxon_716546 .

obo:NCBITaxon_990719 a rdfs:Class ;
  rdfs:label "Christensenellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_186801 .

obo:NCBITaxon_360807 a rdfs:Class ;
  rdfs:label "Roseburia inulinivorans" ;
  rdfs:subClassOf obo:NCBITaxon_841 .

obo:OHMI_0000892 a rdfs:Class ;
  rdfs:label "expansion of Desulfovibrio in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Desulfovibrio up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000672 a rdfs:Class ;
  rdfs:label "MDD human gut microbiome interaction" ;
  rdfs:comment "Human gut microbiome interaction where a person has Major Depressive Disorder (MDD)." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:BFO_0000006 a rdfs:Class ;
  rdfs:label "spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:OHMI_0000194 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides fragilis in arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Bacteroides fragilis in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000192 .

obo:OHMI_0000802 a rdfs:Class ;
  rdfs:label "depletion of Nannocystis sp. in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Nannocystis sp. down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:IAO_8000000 a rdfs:Class ;
  rdfs:label "ontology module"@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:OHMI_0000689 a rdfs:Class ;
  rdfs:label "expansion of Vibrio scophthalmi in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Vibrio scophthalmi up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000779 a rdfs:Class ;
  rdfs:label "depletion of Lactobacillus sp. in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Lactobacillus sp. down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:PATO_0001018 a rdfs:Class ;
  rdfs:label "physical quality" ;
  rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OHMI_0000336 a rdfs:Class ;
  rdfs:label "depletion of Prevotellaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Prevotellaceae is decreased." ;
  rdfs:subClassOf obo:OHMI_0000360 .

obo:IAO_8000018 a rdfs:Class ;
  rdfs:label "obo basic subset ontology module"@en ;
  rdfs:comment """A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.

Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).

An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports"""@en ;
  rdfs:seeAlso <http://owlcollab.github.io/oboformat/doc/obo-syntax.html#6.2> ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:OHMI_0000932 a rdfs:Class ;
  rdfs:label "depletion of Firmicutes in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Firmicutes down-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:NCBITaxon_862965 a rdfs:Class ;
  rdfs:label "Haemophilus parainfluenzae T3T1" ;
  rdfs:subClassOf obo:NCBITaxon_729 .

obo:NCBITaxon_33035 a rdfs:Class ;
  rdfs:label "Blautia producta" ;
  rdfs:subClassOf obo:NCBITaxon_572511 .

obo:OHMI_0000453 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted (compared to fibromyalgia patients) in gut of human with disease"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OHMI_0000589 a rdfs:Class ;
  rdfs:label "expansion of Pseudomonas in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Pseudomonas up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000048 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium dentium in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Bifidobacterium dentium in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000085 .

obo:OHMI_0000756 a rdfs:Class ;
  rdfs:label "expansion of Lachnoanaerobaculum in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Lachnoanaerobaculum up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:DOID_305 a rdfs:Class ;
  rdfs:label "carcinoma" ;
  rdfs:comment "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." ;
  rdfs:subClassOf obo:DOID_162 .

obo:NCBITaxon_1839 a rdfs:Class ;
  rdfs:label "Nocardioides" ;
  rdfs:subClassOf obo:NCBITaxon_85009 .

obo:OHMI_0000012 a rdfs:Class ;
  rdfs:label "interaction between microbiome and adaptive immune system"@en ;
  rdfs:comment "A interaction between microbiome and host immune system where the immune system is the host adaptive immune system" ;
  rdfs:subClassOf obo:OHMI_0000011 .

obo:OHMI_0000618 a rdfs:Class ;
  rdfs:label "expansion of Balneimonas  in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Balneimonas  up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000219 a rdfs:Class ;
  rdfs:label "expansion of Micrococcus in RA human respiratory airway"@en ;
  rdfs:comment "RA human respiratory airway  microbiome interaction that shows an expansion of Micrococcus in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000078 .

obo:NCBITaxon_1417852 a rdfs:Class ;
  rdfs:label "Flintibacter butyricus" ;
  rdfs:subClassOf obo:NCBITaxon_538999 .

obo:NCBITaxon_1506553 a rdfs:Class ;
  rdfs:label "Lachnoclostridium" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OBI_0666667 a rdfs:Class ;
  rdfs:label "nucleic acid extraction"@en ;
  rdfs:comment "a material separation to recover the nucleic acid fraction of an input material"@en ;
  rdfs:subClassOf obo:OBI_0302884 .

obo:NCBITaxon_1305 a rdfs:Class ;
  rdfs:label "Streptococcus sanguinis"@en ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:OBI_0000047 a rdfs:Class ;
  rdfs:label "processed material"@en ;
  rdfs:comment "Is a material entity that is created or changed during material processing."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCBITaxon_1686313 a rdfs:Class ;
  rdfs:label "Fenollaria" ;
  rdfs:subClassOf obo:NCBITaxon_538999 .

obo:OHMI_0000435 a rdfs:Class ;
  rdfs:label "expansion of S. dysenteriae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Shigella dysenteriae is increased." ;
  rdfs:subClassOf obo:OHMI_0000402 .

obo:PCO_0000010 a rdfs:Class ;
  rdfs:label "community species richness"@en ;
  rdfs:comment "The number of different species represented in an ecological community."@en ;
  rdfs:subClassOf obo:PCO_0000004 .

obo:OHMI_0000406 a rdfs:Class ;
  rdfs:label "expansion of Clostridia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Clostridia is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000506 a rdfs:Class ;
  rdfs:label "expansion of Pseudomonas aeruginosa in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Pseudomonas aeruginosa up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_265570 a rdfs:Class ;
  rdfs:label "Sulfurovum" ;
  rdfs:subClassOf obo:NCBITaxon_213849 .

obo:OHMI_0000548 a rdfs:Class ;
  rdfs:label "expansion of Aeromonadales in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Aeromonadales up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000189 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillus acidophilus in arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Lactobacillus acidophilus in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000191 .

obo:OHMI_0000924 a rdfs:Class ;
  rdfs:label "depletion of Bifidobacterium animalis in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium animalis down-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000297 a rdfs:Class ;
  rdfs:label "expansion of Streptobacillus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Streptobacillus is increased." ;
  rdfs:subClassOf obo:OHMI_0000285 .

obo:OHMI_0000369 a rdfs:Class ;
  rdfs:label "expansion of Peptostreptococcaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Peptostreptococcaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:OHMI_0000796 a rdfs:Class ;
  rdfs:label "depletion of Clostridium sp. CAG:510 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Clostridium sp. CAG:510 down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_1872650 a rdfs:Class ;
  rdfs:label "Atopobium sp." ;
  rdfs:subClassOf obo:NCBITaxon_1380 .

obo:OHMI_0000737 a rdfs:Class ;
  rdfs:label "expansion of Dysosmobacter in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Dysosmobacter up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_469 a rdfs:Class ;
  rdfs:label "Acinetobacter" ;
  rdfs:subClassOf obo:NCBITaxon_468 .

obo:OHMI_0000913 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacterium in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Faecalibacterium down-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000446 a rdfs:Class ;
  rdfs:label "expansion of E. faecalis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Enterococcus faecalis is increased." ;
  rdfs:subClassOf obo:OHMI_0000399 .

obo:NCBITaxon_1224 a rdfs:Class ;
  rdfs:label "Pseudomonadota" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:NCBITaxon_33024 a rdfs:Class ;
  rdfs:label "Phascolarctobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_909930 .

obo:NCBITaxon_29547 a rdfs:Class ;
  rdfs:label "Campylobacterota" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:UBERON_0000059 a rdfs:Class ;
  rdfs:label "large intestine" ;
  rdfs:comment "A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]." ;
  rdfs:subClassOf obo:UBERON_0004921 , obo:UBERON_0013765 .

obo:NCBITaxon_562 a rdfs:Class ;
  rdfs:label "Escherichia coli" ;
  rdfs:subClassOf obo:NCBITaxon_561 .

obo:OHMI_0000131 a rdfs:Class ;
  rdfs:label "expansion of E. coli ETEC TW03439 in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Escherichia coli ETEC TW03439 in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:OHMI_0000309 a rdfs:Class ;
  rdfs:label "depletion of Serratia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Serratia is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_1653 a rdfs:Class ;
  rdfs:label "Corynebacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_85007 .

obo:OHMI_0000716 a rdfs:Class ;
  rdfs:label "expansion of Flintibacter butyricus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Flintibacter butyricus up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000644 a rdfs:Class ;
  rdfs:label "expansion of Desulfovibrionaceae in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Desulfovibrionaceae up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000569 a rdfs:Class ;
  rdfs:label "depletion of Bacteroidetes in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Bacteroidetes down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_28136 a rdfs:Class ;
  rdfs:label "Prevotella oulorum"@en ;
  rdfs:subClassOf obo:NCBITaxon_838 .

obo:OHMI_0000148 a rdfs:Class ;
  rdfs:label "depletion of Robinsoniella in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Robinsoniella in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000127 .

obo:OBI_0302884 a rdfs:Class ;
  rdfs:label "extraction"@en ;
  rdfs:comment "A material separation in which a desired component of an input material is separated from the remainder" ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:OHMI_0000191 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillus in arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Lactobacillus in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:OHMI_0000574 a rdfs:Class ;
  rdfs:label "depletion of Modestobacter in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Modestobacter down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_1437183 a rdfs:Class ;
  rdfs:label "Mesangiospermae" ;
  rdfs:subClassOf obo:NCBITaxon_33090 .

obo:NCBITaxon_310297 a rdfs:Class ;
  rdfs:label "Phocaeicola plebeius" ;
  rdfs:subClassOf obo:NCBITaxon_909656 .

obo:OHMI_0000001 a rdfs:Class ;
  rdfs:label "host-microbiome interaction"@en ;
  rdfs:comment "A biological interaction between a microbiome and its host" ;
  rdfs:subClassOf obo:INO_0000002 .

obo:OHMI_0000634 a rdfs:Class ;
  rdfs:label "depletion of Haemophilus parahaemolyticus in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Haemophilus parahaemolyticus down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000305 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidales in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroidales is increased." ;
  rdfs:subClassOf obo:OHMI_0000397 .

obo:OHMI_0000417 a rdfs:Class ;
  rdfs:label "expansion of P. anaerobius in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Peptostreptococcus anaerobius is increased." ;
  rdfs:subClassOf obo:OHMI_0000288 .

obo:UO_0000003 a rdfs:Class ;
  rdfs:label "time unit" ;
  rdfs:comment "A unit which is a standard measure of the dimension in which events occur in sequence." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:OHMI_0000081 a rdfs:Class ;
  rdfs:label "depletion of Pseudobutyrivibrio in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows a depletion of Pseudobutyrivibrio in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000053 .

obo:NCBITaxon_753642 a rdfs:Class ;
  rdfs:label "Escherichia coli NC101" ;
  rdfs:subClassOf obo:NCBITaxon_562 .

obo:OHMI_0000179 a rdfs:Class ;
  rdfs:label "expansion of Leptotrichia sp. in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of Leptotrichia sp. in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:NCBITaxon_2879119 a rdfs:Class ;
  rdfs:label "Arsenophonus apicola" ;
  rdfs:subClassOf obo:NCBITaxon_1903414 .

obo:OHMI_0000003 a rdfs:Class ;
  rdfs:label "microbiome"@en ;
  rdfs:comment "A biome that consists of a collection of microorganisms (i.e., microbiota) and the surrounding environment where the microorganisms reside." ;
  rdfs:subClassOf obo:ENVO_00000428 .

obo:OBI_0000968 a rdfs:Class ;
  rdfs:label "device" ;
  rdfs:comment "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OHMI_0000558 a rdfs:Class ;
  rdfs:label "expansion of Campylobacter in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Campylobacter up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_239759 a rdfs:Class ;
  rdfs:label "Alistipes" ;
  rdfs:subClassOf obo:NCBITaxon_171550 .

obo:OHMI_0000820 a rdfs:Class ;
  rdfs:label "depletion of Weissella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Weissella down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000346 a rdfs:Class ;
  rdfs:label "depletion of Lachnospiraceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Lachnospiraceae is decreased." ;
  rdfs:subClassOf obo:OHMI_0000356 .

obo:OHMI_0000881 a rdfs:Class ;
  rdfs:label "depletion of Firmicutes in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Firmicutes down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_1897022 a rdfs:Class ;
  rdfs:label "Subdoligranulum sp. 60_17" ;
  rdfs:subClassOf obo:NCBITaxon_292632 .

obo:IAO_8000010 a rdfs:Class ;
  rdfs:label "exclusion subset ontology module"@en ;
  rdfs:comment "A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:NCBITaxon_1434006 a rdfs:Class ;
  rdfs:label "Fretibacterium" ;
  rdfs:subClassOf obo:NCBITaxon_649776 .

obo:OHMI_0000174 a rdfs:Class ;
  rdfs:label "depletion of Neisseria sp. in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of Neisseria sp. in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:OHMI_0000870 a rdfs:Class ;
  rdfs:label "depletion of Hydrogenoanaerobacterium in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Hydrogenoanaerobacterium down-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_158847 a rdfs:Class ;
  rdfs:label "Megamonas hypermegale" ;
  rdfs:subClassOf obo:NCBITaxon_158846 .

obo:OHMI_0000677 a rdfs:Class ;
  rdfs:label "bacterial change in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "MDD human gut microbiome interaction that shows an change of bacteria in adolescent patients with MDD compared to healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000672 .

obo:OHMI_0000391 a rdfs:Class ;
  rdfs:label "depletion of S. thermophilus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Streptococcus thermophilus is decreased." ;
  rdfs:subClassOf obo:OHMI_0000394 .

obo:NCBITaxon_59201 a rdfs:Class ;
  rdfs:label "Salmonella enterica subsp. enterica" ;
  rdfs:subClassOf obo:NCBITaxon_28901 .

obo:OHMI_0000731 a rdfs:Class ;
  rdfs:label "expansion of Odoribacter in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Odoribacter up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_32025 a rdfs:Class ;
  rdfs:label "Helicobacter hepaticus" ;
  rdfs:subClassOf obo:NCBITaxon_209 .

obo:OHMI_0000727 a rdfs:Class ;
  rdfs:label "expansion of Coriobacterium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Coriobacterium up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_851 a rdfs:Class ;
  rdfs:label "Fusobacterium nucleatum" ;
  rdfs:subClassOf obo:NCBITaxon_848 .

obo:OHMI_0000533 a rdfs:Class ;
  rdfs:label "expansion of Lachnospiraceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Lachnospiraceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000747 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000894 a rdfs:Class ;
  rdfs:label "expansion of Actinomyces in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Actinomyces up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_1920173 a rdfs:Class ;
  rdfs:label "Paraglaciecola sp." ;
  rdfs:subClassOf obo:NCBITaxon_135622 .

obo:OHMI_0000488 a rdfs:Class ;
  rdfs:label "human-stomach microbiome interaction"@en ;
  rdfs:comment "A human gut-microbiome interaction where the gut is specifically stomach." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:NCBITaxon_544 a rdfs:Class ;
  rdfs:label "Citrobacter" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:NCBITaxon_1783272 a rdfs:Class ;
  rdfs:label "Bacillati" ;
  rdfs:subClassOf obo:NCBITaxon_2 .

obo:NCBITaxon_84108 a rdfs:Class ;
  rdfs:label "Slackia" ;
  rdfs:subClassOf obo:NCBITaxon_1643826 .

obo:OHMI_0000585 a rdfs:Class ;
  rdfs:label "expansion of Ehrlichia in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Ehrlichia up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000120 a rdfs:Class ;
  rdfs:label "expansion of Negativicutes in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Negativicutes in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:NCBITaxon_186827 a rdfs:Class ;
  rdfs:label "Aerococcaceae" ;
  rdfs:subClassOf obo:NCBITaxon_186826 .

obo:NCBITaxon_1622 a rdfs:Class ;
  rdfs:label "Ligilactobacillus murinus" ;
  rdfs:subClassOf obo:NCBITaxon_2767887 .

obo:OHMI_0000283 a rdfs:Class ;
  rdfs:label "expansion of S. moorei in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Solobacterium moorei is increased." ;
  rdfs:subClassOf obo:OHMI_0000295 .

obo:OBI_0600036 a rdfs:Class ;
  rdfs:label "establishing cell culture" ;
  rdfs:comment "a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line)." ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OHMI_0000185 a rdfs:Class ;
  rdfs:label "expansion of Propionibacterium acnes 17B in arthritis  rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Propionibacterium acnes 17B in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:NCBITaxon_2742598 a rdfs:Class ;
  rdfs:label "Limosilactobacillus" ;
  rdfs:subClassOf obo:NCBITaxon_33958 .

obo:DOID_77 a rdfs:Class ;
  rdfs:label "gastrointestinal system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in the gastrointestinal tract." ;
  rdfs:subClassOf obo:DOID_7 .

obo:OHMI_0000655 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacterium in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Faecalibacterium down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OBI_0001108 a rdfs:Class ;
  rdfs:label "nucleic acid sequencer" ;
  rdfs:comment "An device that is used to determine the order of nucleotides in nucleic acid sequences." ;
  rdfs:subClassOf obo:OBI_0000832 .

obo:OHMI_0000736 a rdfs:Class ;
  rdfs:label "expansion of Sellimonas in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Sellimonas up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000327 a rdfs:Class ;
  rdfs:label "expansion of Acidaminobacter in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Acidaminobacter is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:NCBITaxon_28112 a rdfs:Class ;
  rdfs:label "Tannerella forsythia" ;
  rdfs:subClassOf obo:NCBITaxon_195950 .

obo:OHMI_0000645 a rdfs:Class ;
  rdfs:label "expansion of Fusobacteriaceae in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Fusobacteriaceae up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000324 a rdfs:Class ;
  rdfs:label "depletion of D. invisus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Dialister invisus is decreased." ;
  rdfs:subClassOf obo:OHMI_0000356 .

obo:DOID_7148 a rdfs:Class ;
  rdfs:label "rheumatoid arthritis" ;
  rdfs:comment "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint." ;
  rdfs:subClassOf obo:DOID_848 .

obo:NCBITaxon_553372 a rdfs:Class ;
  rdfs:label "Asaccharobacter" ;
  rdfs:subClassOf obo:NCBITaxon_1643826 .

obo:OHMI_0000752 a rdfs:Class ;
  rdfs:label "expansion of Olsenella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Olsenella up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OBI_0000453 a rdfs:Class ;
  rdfs:label "measure function"@en ;
  rdfs:comment "Measure function is a function that is borne by a processed material  and realized in a process in which information about some entity is expressed relative to some reference."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:NCBITaxon_33039 a rdfs:Class ;
  rdfs:label "[Ruminococcus] torques" ;
  rdfs:subClassOf obo:NCBITaxon_2316020 .

obo:OHMI_0000477 a rdfs:Class ;
  rdfs:label "host microbiome restoration by antibiotics"@en ;
  rdfs:comment "host microbiome restoration by an antibiotics treatment" ;
  rdfs:subClassOf obo:OHMI_0000475 .

obo:NCBITaxon_39488 a rdfs:Class ;
  rdfs:label "Anaerobutyricum hallii" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_1301 a rdfs:Class ;
  rdfs:label "Streptococcus" ;
  rdfs:subClassOf obo:NCBITaxon_1300 .

obo:NCBITaxon_5481 a rdfs:Class ;
  rdfs:label "Diutina rugosa" ;
  rdfs:subClassOf obo:NCBITaxon_766764 .

obo:OHMI_0000666 a rdfs:Class ;
  rdfs:label "disease exacerbation"@en ;
  rdfs:comment "A process quality in which a disease is in its stage of execerbation." ;
  rdfs:subClassOf obo:PATO_0001236 .

obo:OHMI_0000724 a rdfs:Class ;
  rdfs:label "expansion of Ruminococcus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Ruminococcus up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000544 a rdfs:Class ;
  rdfs:label "expansion of Fusobacteriaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Fusobacteriaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000439 a rdfs:Class ;
  rdfs:label "expansion of Pseudomonas in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Pseudomonas is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:NCBITaxon_526525 a rdfs:Class ;
  rdfs:label "Erysipelotrichales" ;
  rdfs:subClassOf obo:NCBITaxon_1239 .

obo:NCBITaxon_41297 a rdfs:Class ;
  rdfs:label "Sphingomonadaceae" ;
  rdfs:subClassOf obo:NCBITaxon_28211 .

obo:NCBITaxon_218538 a rdfs:Class ;
  rdfs:label "Dialister invisus" ;
  rdfs:subClassOf obo:NCBITaxon_39948 .

obo:NCBITaxon_544448 a rdfs:Class ;
  rdfs:label "Mycoplasmatota" ;
  rdfs:subClassOf obo:NCBITaxon_1783272 .

obo:NCBITaxon_411475 a rdfs:Class ;
  rdfs:label "Flavonifractor plautii ATCC 29863" ;
  rdfs:subClassOf obo:NCBITaxon_946234 .

obo:OHMI_0000014 a rdfs:Class ;
  rdfs:label "microbiome in human respiratory system"@en ;
  rdfs:comment "a human microbiome that is located in a human lung" ;
  rdfs:subClassOf obo:OHMI_0000002 .

obo:OHMI_0000276 a rdfs:Class ;
  rdfs:label "expansion of P. micra in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Parvimonas micra is increased." ;
  rdfs:subClassOf obo:OHMI_0000287 .

obo:OHMI_0000713 a rdfs:Class ;
  rdfs:label "expansion of Ruminococcus torques in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Ruminococcus torques up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_970 a rdfs:Class ;
  rdfs:label "Selenomonas" ;
  rdfs:subClassOf obo:NCBITaxon_1843491 .

obo:OBI_0000684 a rdfs:Class ;
  rdfs:label "specimen collection objective" ;
  rdfs:comment "A objective specification to obtain a material entity for potential use as an input during an investigation." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:NCBITaxon_10407 a rdfs:Class ;
  rdfs:label "Hepatitis B virus" ;
  rdfs:subClassOf obo:NCBITaxon_2732514 .

obo:OHMI_0000702 a rdfs:Class ;
  rdfs:label "expansion of Eubacterium rectale ATCC 33656 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Eubacterium rectale ATCC 33656 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000767 a rdfs:Class ;
  rdfs:label "expansion of Flavobacteriaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Flavobacteriaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_1720294 a rdfs:Class ;
  rdfs:label "Eisenbergiella massiliensis" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_204516 a rdfs:Class ;
  rdfs:label "Phocaeicola massiliensis" ;
  rdfs:subClassOf obo:NCBITaxon_909656 .

obo:OHMI_0000650 a rdfs:Class ;
  rdfs:label "depletion of Bacteroidetes in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Bacteroidetes down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000570 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Prevotella down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000210 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidia in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an expansion of Bacteroidia in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000113 .

obo:OHMI_0000268 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an decrease of Prevotella stercorea in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000265 .

obo:OHMI_0000554 a rdfs:Class ;
  rdfs:label "expansion of Desulfobulbus in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Desulfobulbus up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000805 a rdfs:Class ;
  rdfs:label "depletion of Gordonia insulae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Gordonia insulae down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_68766 a rdfs:Class ;
  rdfs:label "Fusobacterium sp." ;
  rdfs:subClassOf obo:NCBITaxon_848 .

obo:OHMI_0000850 a rdfs:Class ;
  rdfs:label "expansion of Eggerthella in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Eggerthella up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_283168 a rdfs:Class ;
  rdfs:label "Odoribacter" ;
  rdfs:subClassOf obo:NCBITaxon_1853231 .

obo:NCBITaxon_1743 a rdfs:Class ;
  rdfs:label "Propionibacterium" ;
  rdfs:subClassOf obo:NCBITaxon_31957 .

obo:NCBITaxon_9031 a rdfs:Class ;
  rdfs:label "Gallus gallus" ;
  rdfs:subClassOf obo:NCBITaxon_32524 .

obo:NCBITaxon_84163 a rdfs:Class ;
  rdfs:label "Cryptobacterium curtum" ;
  rdfs:subClassOf obo:NCBITaxon_84162 .

obo:OHMI_0000693 a rdfs:Class ;
  rdfs:label "expansion of Phocaeicola dorei in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Phocaeicola dorei up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000129 a rdfs:Class ;
  rdfs:label "expansion of Erysipelatoclostridium in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Erysipelatoclostridium in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:IDO_0000586 a rdfs:Class ;
  rdfs:label "infection"@en ;
  rdfs:comment "A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OHMI_0000757 a rdfs:Class ;
  rdfs:label "expansion of Lachnoclostridium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Lachnoclostridium up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_482 a rdfs:Class ;
  rdfs:label "Neisseria" ;
  rdfs:subClassOf obo:NCBITaxon_481 .

obo:NCBITaxon_29465 a rdfs:Class ;
  rdfs:label "Veillonella" ;
  rdfs:subClassOf obo:NCBITaxon_31977 .

obo:PCO_0000076 a rdfs:Class ;
  rdfs:label "gamma diversity"@en ;
  rdfs:comment "A community species diversity that is the total species diversity in a landscape. The area or landscape of interest may be of very different sizes in different situations, but it should encompass multiple sites or habitats as measured by alpha diversity." ;
  rdfs:subClassOf obo:PCO_0000019 .

obo:UBERON_0001062 a rdfs:Class ;
  rdfs:label "anatomical entity" ;
  rdfs:comment "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OHMI_0000903 a rdfs:Class ;
  rdfs:label "expansion of Coriobacteriaceae in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Coriobacteriaceae up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_46205 a rdfs:Class ;
  rdfs:label "Pseudobutyrivibrio" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:PATO_0001241 a rdfs:Class ;
  rdfs:label "physical object quality" ;
  rdfs:comment "A quality which inheres in a continuant." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OHMI_0000910 a rdfs:Class ;
  rdfs:label "depletion of Roseburia homini in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Roseburia homini down-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_2093857 a rdfs:Class ;
  rdfs:label "Dysosmobacter welbionis" ;
  rdfs:subClassOf obo:NCBITaxon_2591381 .

obo:NCBITaxon_80864 a rdfs:Class ;
  rdfs:label "Comamonadaceae" ;
  rdfs:subClassOf obo:NCBITaxon_80840 .

obo:OHMI_0000861 a rdfs:Class ;
  rdfs:label "depletion of Phocaeicola plebeius in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Phocaeicola plebeius down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000601 a rdfs:Class ;
  rdfs:label "depletion of Dialister in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Dialister down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000742 a rdfs:Class ;
  rdfs:label "expansion of Peptostreptococcus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Peptostreptococcus up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000831 a rdfs:Class ;
  rdfs:label "depletion of Hyphomicrobiales in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Hyphomicrobiales down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_46123 a rdfs:Class ;
  rdfs:label "Abiotrophia" ;
  rdfs:subClassOf obo:NCBITaxon_186827 .

obo:NCBITaxon_610130 a rdfs:Class ;
  rdfs:label "[Clostridium] saccharolyticum WM1" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_28052 a rdfs:Class ;
  rdfs:label "Lachnospira pectinoschiza" ;
  rdfs:subClassOf obo:NCBITaxon_28050 .

obo:OHMI_0000221 a rdfs:Class ;
  rdfs:label "expansion of Natronobacillus in diarrheal patient gut"@en ;
  rdfs:comment "a diarrheal patient-gut microbiome interaction that shows an increase of Prevotella in patients in the gut of human diarrheal patient compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000067 .

obo:OHMI_0000688 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium sp. in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium sp. up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000051 a rdfs:Class ;
  rdfs:label "segregation of Prevotella or Bacteroides dominance in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows high Prevotella or high Bacteroides relative abundance, but rarely a high relative abundance of both." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:NCBITaxon_830 a rdfs:Class ;
  rdfs:label "Butyrivibrio" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000565 a rdfs:Class ;
  rdfs:label "expansion of Firmicutes in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Firmicutes up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000137 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides caccae in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Bacteroides caccae in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000116 .

obo:NCBITaxon_3082720 a rdfs:Class ;
  rdfs:label "Peptostreptococcales" ;
  rdfs:subClassOf obo:NCBITaxon_186801 .

obo:PCO_0000080 a rdfs:Class ;
  rdfs:label "plant density of an ecological community"@en ;
  rdfs:comment "The density of plants in an ecological community (multiple species), often measured as the number of plants per area." ;
  rdfs:subClassOf obo:PCO_0000004 , obo:PCO_0000077 .

obo:NCBITaxon_358743 a rdfs:Class ;
  rdfs:label "Enterocloster citroniae" ;
  rdfs:subClassOf obo:NCBITaxon_2719313 .

obo:OHMI_0000410 a rdfs:Class ;
  rdfs:label "expansion of Proteobacteria in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction whereProteobacteria is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:PCO_0000004 a rdfs:Class ;
  rdfs:label "quality of an ecological community"@en ;
  rdfs:comment "A quality that inheres in a community."@en ;
  rdfs:subClassOf obo:PATO_0002003 .

obo:NCBITaxon_155615 a rdfs:Class ;
  rdfs:label "Fusobacterium vincentii" ;
  rdfs:subClassOf obo:NCBITaxon_848 .

obo:OHMI_0000036 a rdfs:Class ;
  rdfs:label "human oral cavity microbiome interaction"@en ;
  rdfs:comment "An interaction between human and oral microbiome." ;
  rdfs:subClassOf obo:OHMI_0000019 .

obo:OHMI_0000624 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Prevotella down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000086 a rdfs:Class ;
  rdfs:label "depletion of Cardiobacterium in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity microbiome interaction that shows an decrease of Cardiobacterium in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:OHMI_0000180 a rdfs:Class ;
  rdfs:label "expansion of Tannerella forsythia in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of rare taxa,Tannerella forsythia in patients with RA compared with healthy controls" ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:OHMI_0000581 a rdfs:Class ;
  rdfs:label "depletion of Acidaminococcaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Acidaminococcaceae down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_46255 a rdfs:Class ;
  rdfs:label "Weissella" ;
  rdfs:subClassOf obo:NCBITaxon_33958 .

obo:OHMI_0000900 a rdfs:Class ;
  rdfs:label "expansion of Enterobacteriaceae in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Enterobacteriaceae up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000025 a rdfs:Class ;
  rdfs:label "human gut microbiome and Clostridium difficile interaction"@en ;
  rdfs:comment "A human-gut microbiome interaction that involves in Clostridium difficile" ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:NCBITaxon_2157 a rdfs:Class ;
  rdfs:label "Archaea" ;
  rdfs:subClassOf obo:COB_0000022 .

obo:OBI_1110021 a rdfs:Class ;
  rdfs:label "infection process"@en ;
  rdfs:comment "the detrimental process in which an infectious agent colonizes or replicates in a host environment"@en ;
  rdfs:subClassOf obo:OBI_1110122 .

obo:OHMI_0000421 a rdfs:Class ;
  rdfs:label "expansion of Selenomonas in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Selenomonas is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000768 a rdfs:Class ;
  rdfs:label "expansion of Rikenellaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Rikenellaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000164 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidetes in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an expansion of Bacteroidetes in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000122 .

obo:OHMI_0000842 a rdfs:Class ;
  rdfs:label "expansion of Acetanaerobacterium in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Acetanaerobacterium up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:BFO_0000141 a rdfs:Class ;
  rdfs:label "immaterial entity"@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:UBERON_0001088 a rdfs:Class ;
  rdfs:label "urine" ;
  rdfs:comment "Excretion that is the output of a kidney" ;
  rdfs:subClassOf obo:UBERON_0000174 .

obo:OHMI_0000201 a rdfs:Class ;
  rdfs:label "expansion of Streptococcaceae in SLE  mouse gut"@en ;
  rdfs:comment "An association of musculus gut microbiota with system lupus erythematosus(SLE) that shows an expansion of Streptococcaceae in musculus with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000197 .

obo:DOID_3083 a rdfs:Class ;
  rdfs:label "chronic obstructive pulmonary disease" ;
  rdfs:subClassOf obo:DOID_7 .

obo:OHMI_0000451 a rdfs:Class ;
  rdfs:label "expansion of S. gallolyticus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Streptococcus gallolyticus is increased." ;
  rdfs:subClassOf obo:OHMI_0000367 .

obo:OHMI_0000238 a rdfs:Class ;
  rdfs:label "depletion of Streptococcus sanguinis in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity microbiome interaction that shows an decrease of Streptococcus sanguinis in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:NCBITaxon_51160 a rdfs:Class ;
  rdfs:label "Treponema maltophilum"@en ;
  rdfs:subClassOf obo:NCBITaxon_157 .

obo:OHMI_0000075 a rdfs:Class ;
  rdfs:label "depletion of Porphyromonas in RA human gut compared to fibromyalgia patients"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Porphyromonas in patients with RA compared to fibromyalgia patients" ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000492 a rdfs:Class ;
  rdfs:label "bacterial change in lung of COPD patient compared to healthy human"@en ;
  rdfs:comment "COPD human respiratory airway microbiome interaction that shows an change of bacteria in patients with COPD compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000489 .

obo:OHMI_0000875 a rdfs:Class ;
  rdfs:label "depletion of Enterorhabdus in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Enterorhabdus down-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:DOID_219 a rdfs:Class ;
  rdfs:label "colon cancer" ;
  rdfs:comment "A large intestine cancer that is located_in the colon." ;
  rdfs:subClassOf obo:DOID_5672 .

obo:OHMI_0000705 a rdfs:Class ;
  rdfs:label "expansion of Oscillibacter valericigenes sjm18-20 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Oscillibacter valericigenes sjm18-20 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_1649459 a rdfs:Class ;
  rdfs:label "Hungatella" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000212 a rdfs:Class ;
  rdfs:label "depletion of Clostridia in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an decrease of Vibrio  in patients with SLEcompared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000112 .

obo:NCBITaxon_577309 a rdfs:Class ;
  rdfs:label "Paraprevotella" ;
  rdfs:subClassOf obo:NCBITaxon_171552 .

obo:NCBITaxon_85031 a rdfs:Class ;
  rdfs:label "Nakamurellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1760 .

obo:OHMI_0000062 a rdfs:Class ;
  rdfs:label "depletion of Shigella in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Shigella is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000292 a rdfs:Class ;
  rdfs:label "expansion of Leptotrichia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Leptotrichia is increased." ;
  rdfs:subClassOf obo:OHMI_0000285 .

obo:NCBITaxon_367928 a rdfs:Class ;
  rdfs:label "Bifidobacterium adolescentis ATCC 15703" ;
  rdfs:subClassOf obo:NCBITaxon_1678 .

obo:OHMI_0000543 a rdfs:Class ;
  rdfs:label "expansion of Leptotrichia in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Leptotrichia up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000921 a rdfs:Class ;
  rdfs:label "expansion of Lawsonibacter in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Lawsonibacter up-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000287 a rdfs:Class ;
  rdfs:label "expansion of Parvimonas in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Parvimonas is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:CL_0000010 a rdfs:Class ;
  rdfs:label "cultured cell" ;
  rdfs:comment "A cell in vitro that is or has been maintained or propagated as part of a cell culture." ;
  rdfs:subClassOf obo:CL_0000578 .

obo:OHMI_0000361 a rdfs:Class ;
  rdfs:label "depletion of Rikenellaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Rikenellaceae is decreased." ;
  rdfs:subClassOf obo:OHMI_0000360 .

obo:OHMI_0000763 a rdfs:Class ;
  rdfs:label "expansion of Streptococcaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Streptococcaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000593 a rdfs:Class ;
  rdfs:label "depletion of Clostridia in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Clostridia down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_137 a rdfs:Class ;
  rdfs:label "Spirochaetaceae" ;
  rdfs:subClassOf obo:NCBITaxon_136 .

obo:NCBITaxon_909932 a rdfs:Class ;
  rdfs:label "Negativicutes" ;
  rdfs:subClassOf obo:NCBITaxon_1239 .

obo:NCBITaxon_3384194 a rdfs:Class ;
  rdfs:label "Thermotogati" ;
  rdfs:subClassOf obo:NCBITaxon_2 .

obo:NCBITaxon_841 a rdfs:Class ;
  rdfs:label "Roseburia" ;
  rdfs:subClassOf obo:NCBITaxon_186803 , obo:OHMI_0000671 .

obo:NCBITaxon_817 a rdfs:Class ;
  rdfs:label "Bacteroides fragilis" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:OHMI_0000153 a rdfs:Class ;
  rdfs:label "depletion of Akkermansia in PsA human gut"@en ;
  rdfs:comment "a PsA human-gut microbiome interaction that shows an decrease of Akkermansia in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000156 .

obo:IAO_8000007 a rdfs:Class ;
  rdfs:label "curation subset ontology module"@en ;
  rdfs:comment "A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OHMI_0000257 a rdfs:Class ;
  rdfs:label "expansion of Enterobacteriaceae  in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Enterobacteriaceae in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000255 .

obo:OHMI_0000505 a rdfs:Class ;
  rdfs:label "expansion of Streptococcus pneumoniae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Streptococcus pneumoniae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_46506 a rdfs:Class ;
  rdfs:label "Bacteroides stercoris" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:GO_0010467 a rdfs:Class ;
  rdfs:label "gene expression" ;
  rdfs:comment "The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:OHMI_0000613 a rdfs:Class ;
  rdfs:label "expansion of Haemophilus in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Haemophilus up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000159 a rdfs:Class ;
  rdfs:label "expansion of Streptococcus in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an expansion of Streptococcus in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000163 .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity"@en ;
  rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:OHMI_0000661 a rdfs:Class ;
  rdfs:label "depletion of Gemella in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Gemella down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000462 a rdfs:Class ;
  rdfs:label "invisible to unaided eye"@en ;
  rdfs:comment "A physical object quality that is inhered in a material entity that is too small to be viewed by the unaided eye." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OHMI_0000886 a rdfs:Class ;
  rdfs:label "expansion of Campylobacter in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Campylobacter up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000091 a rdfs:Class ;
  rdfs:label "expansion of Prevotella copri in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Prevotella copri in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000038 .

obo:CMO_0001531 a rdfs:Class ;
  rdfs:label "blood immunoglobulin measurement" ;
  rdfs:comment "Any measurement related to immunoglobulins, any of several classes of proteins produced by plasma cells and lymphocytes which play essential roles in the immune system, for example, attaching to foreign substances in an effort to destroy them, in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." ;
  rdfs:subClassOf obo:CMO_0000000 .

obo:NCBITaxon_1496 a rdfs:Class ;
  rdfs:label "Clostridioides difficile" ;
  rdfs:subClassOf obo:NCBITaxon_186804 .

obo:OHMI_0000371 a rdfs:Class ;
  rdfs:label "expansion of Pasteurellaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Pasteurellaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:NCBITaxon_464821 a rdfs:Class ;
  rdfs:label "coliform bacterium 3-80" ;
  rdfs:subClassOf obo:NCBITaxon_2 .

obo:OHMI_0000087 a rdfs:Class ;
  rdfs:label "depletion of Eikenella in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity microbiome interaction that shows an decrease of Eikenella in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:NCBITaxon_1308 a rdfs:Class ;
  rdfs:label "Streptococcus thermophilus" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:OHMI_0000134 a rdfs:Class ;
  rdfs:label "expansion of Paraprevotella in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Paraprevotella in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000117 .

obo:OHMI_0000704 a rdfs:Class ;
  rdfs:label "expansion of Clostridium saccharolyticum wm1 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Clostridium saccharolyticum wm1 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000561 a rdfs:Class ;
  rdfs:label "expansion of Prevotella in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Prevotella up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OBI_0000747 a rdfs:Class ;
  rdfs:label "material sample" ;
  rdfs:comment "A material entity that has the material sample role" ;
  rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0100051 .

obo:UBERON_0010000 a rdfs:Class ;
  rdfs:label "multicellular anatomical structure" ;
  rdfs:comment "An anatomical structure that has more than one cell as a part." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:OBI_0000070 a rdfs:Class ;
  rdfs:label "assay"@en ;
  rdfs:comment "A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OHMI_0000186 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillus casei in arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Lactobacillus casei in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:OHMI_0000227 a rdfs:Class ;
  rdfs:label "expansion of Campylobacter in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of Campylobacter in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000099 .

obo:OHMI_0000719 a rdfs:Class ;
  rdfs:label "expansion of Christensenella timonensis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Christensenella timonensis up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000108 a rdfs:Class ;
  rdfs:label "expansion of Prevotella intermedia in AS human oral cavity"@en ;
  rdfs:comment "an AS human oral cavity  microbiome interaction that shows an expansion of Prevotella intermedia in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000106 .

obo:OHMI_0000697 a rdfs:Class ;
  rdfs:label "expansion of Dysosmobacter welbionis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Dysosmobacter welbionis up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OBI_0000275 a rdfs:Class ;
  rdfs:label "analyte role"@en ;
  rdfs:comment "A measurand role borne by a molecular entity or an atom and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role."@en ;
  rdfs:subClassOf obo:OBI_0002444 .

obo:RO_0000081 a rdf:Property ;
  rdfs:label "role of"@en ;
  rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:NCBITaxon_1643824 a rdfs:Class ;
  rdfs:label "Atopobiaceae" ;
  rdfs:subClassOf obo:NCBITaxon_84999 .

obo:NCBITaxon_10090 a rdfs:Class ;
  rdfs:label "Mus musculus" ;
  rdfs:subClassOf obo:NCBITaxon_39107 .

obo:OHMI_0000773 a rdfs:Class ;
  rdfs:label "expansion of Pseudomonadales in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Pseudomonadales up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OBI_0000973 a rdfs:Class ;
  rdfs:label "sequence data"@en ;
  rdfs:comment """A measurement datum that representing the primary structure of a macromolecule(it's sequence) sometimes associated with an indicator of confidence of that measurement.
""" ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OHMI_0000171 a rdfs:Class ;
  rdfs:label "expansion of Porphyromonas gingivalis in AS human oral cavity"@en ;
  rdfs:comment "an AS human oral cavity  microbiome interaction that shows an expansion of Porphyromonas gingivalis in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000106 .

obo:NCBITaxon_1485 a rdfs:Class ;
  rdfs:label "Clostridium" ;
  rdfs:subClassOf obo:NCBITaxon_31979 .

obo:OHMI_0000366 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroidaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000305 .

obo:OHMI_0000328 a rdfs:Class ;
  rdfs:label "expansion of Phascolarctobacterium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Phascolarctobacterium is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000399 a rdfs:Class ;
  rdfs:label "expansion of Enterococcaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Enterococcaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_2624479 a rdfs:Class ;
  rdfs:label "unclassified Eubacterium (in: firmicutes)" ;
  rdfs:subClassOf obo:NCBITaxon_1730 .

obo:NCBITaxon_1350 a rdfs:Class ;
  rdfs:label "Enterococcus" ;
  rdfs:subClassOf obo:NCBITaxon_81852 .

obo:NCBITaxon_447020 a rdfs:Class ;
  rdfs:label "Adlercreutzia" ;
  rdfs:subClassOf obo:NCBITaxon_1643826 .

obo:OHMI_0000759 a rdfs:Class ;
  rdfs:label "expansion of Ruthenibacterium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Ruthenibacterium up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000480 a rdfs:Class ;
  rdfs:label "differentially enriched microbial marker for disease"@en ;
  rdfs:comment "A microbe that is differentially enriched in a microbiome host and can serve as a marker for a disease" ;
  rdfs:subClassOf obo:OHMI_0000460 .

obo:NCBITaxon_41200 a rdfs:Class ;
  rdfs:label "Bifidobacterium sp." ;
  rdfs:subClassOf obo:NCBITaxon_1678 .

obo:NCBITaxon_1678 a rdfs:Class ;
  rdfs:label "Bifidobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_31953 , obo:OHMI_0000671 .

obo:NCBITaxon_363265 a rdfs:Class ;
  rdfs:label "Leyella stercorea" ;
  rdfs:subClassOf obo:NCBITaxon_171552 .

obo:OHMI_0000550 a rdfs:Class ;
  rdfs:label "expansion of Aeromonas in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Aeromonas up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_32257 a rdfs:Class ;
  rdfs:label "Kingella <b-proteobacteria>" ;
  rdfs:subClassOf obo:NCBITaxon_481 .

obo:NCBITaxon_214856 a rdfs:Class ;
  rdfs:label "Alistipes finegoldii" ;
  rdfs:subClassOf obo:NCBITaxon_239759 .

obo:OHMI_0000878 a rdfs:Class ;
  rdfs:label "depletion of Prevotellaceae in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Prevotellaceae down-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_481 a rdfs:Class ;
  rdfs:label "Neisseriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_28216 .

obo:ENVO_00000428 a rdfs:Class ;
  rdfs:label "biome" ;
  rdfs:comment "A biome is an ecosystem to which resident ecological communities have evolved adaptations." ;
  rdfs:subClassOf obo:ENVO_01001110 .

obo:OHMI_0000116 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Bacteroides in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000119 .

obo:OHMI_0000495 a rdfs:Class ;
  rdfs:label "bacterial change in sputum of COPD patient compared to healthy human"@en ;
  rdfs:comment "A COPD human oral microbiome interaction that shows bacterial change in sputum of COPD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000494 .

obo:NCBITaxon_943 a rdfs:Class ;
  rdfs:label "Ehrlichia" ;
  rdfs:subClassOf obo:NCBITaxon_28211 .

obo:NCBITaxon_4892 a rdfs:Class ;
  rdfs:label "Saccharomycetales" ;
  rdfs:subClassOf obo:NCBITaxon_147537 .

obo:OHMI_0000216 a rdfs:Class ;
  rdfs:label "depletion of Burkholderia in RA human respiratory airway"@en ;
  rdfs:comment "RA human respiratory airway microbiome interaction that shows an decrease of Burkholderia in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000078 .

obo:OHMI_0000040 a rdfs:Class ;
  rdfs:label "depletion of Veillonella in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Veillonellain in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:NCBITaxon_39950 a rdfs:Class ;
  rdfs:label "Dialister pneumosintes" ;
  rdfs:subClassOf obo:NCBITaxon_39948 .

obo:OHMI_0000520 a rdfs:Class ;
  rdfs:label "expansion of Streptococcaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Streptococcaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_85006 a rdfs:Class ;
  rdfs:label "Micrococcales" ;
  rdfs:subClassOf obo:NCBITaxon_1760 .

obo:NCBITaxon_10114 a rdfs:Class ;
  rdfs:label "Rattus" ;
  rdfs:subClassOf obo:NCBITaxon_39107 .

obo:IAO_8000017 a rdfs:Class ;
  rdfs:label "ontology module subsetted by expressivity"@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:NCBITaxon__28115 a rdfs:Class ;
  rdfs:label "Porphyromonas macacae"@en ;
  rdfs:subClassOf obo:NCBITaxon_836 .

obo:PCO_0000074 a rdfs:Class ;
  rdfs:label "alpha diversity"@en ;
  rdfs:comment "A community species diversity that is the mean species diversity at a site or within a specific habitat." ;
  rdfs:subClassOf obo:PCO_0000019 .

obo:OHMI_0000431 a rdfs:Class ;
  rdfs:label "expansion of M. avium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Mycobacterium avium is increased." ;
  rdfs:subClassOf obo:OHMI_0000405 .

obo:OHMI_0000145 a rdfs:Class ;
  rdfs:label "depletion of Ruminococcus sp. in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Ruminococcus sp. in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000128 .

obo:NCBITaxon_72274 a rdfs:Class ;
  rdfs:label "Pseudomonadales" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OHMI_0000749 a rdfs:Class ;
  rdfs:label "expansion of Eggerthella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Eggerthella up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000896 a rdfs:Class ;
  rdfs:label "expansion of Eggerthella in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Eggerthella up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:CL_0000000 a rdfs:Class ;
  rdfs:label "cell" ;
  rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OHMI_0000623 a rdfs:Class ;
  rdfs:label "expansion of Aeromonadaceae in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Aeromonadaceae up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000889 a rdfs:Class ;
  rdfs:label "expansion of Parabacteroides in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Parabacteroides up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000076 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in RA human gut compared to fibromyalgia patients"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Prevotella  in patients with RA compared to fibromyalgia patients" ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000069 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillus salivarius in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of Lactobacillus salivarius in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:IAO_8000002 a rdfs:Class ;
  rdfs:label "editors ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OHMI_0000893 a rdfs:Class ;
  rdfs:label "expansion of Atopobium in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Atopobium up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_85009 a rdfs:Class ;
  rdfs:label "Propionibacteriales" ;
  rdfs:subClassOf obo:NCBITaxon_1760 .

obo:NCBITaxon_55194 a rdfs:Class ;
  rdfs:label "Malassezia furfur" ;
  rdfs:subClassOf obo:NCBITaxon_55193 .

obo:NCBITaxon_89152 a rdfs:Class ;
  rdfs:label "Peptacetobacter hiranonis" ;
  rdfs:subClassOf obo:NCBITaxon_186804 .

obo:OHMI_0000333 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroides is increased." ;
  rdfs:subClassOf obo:OHMI_0000366 .

obo:NCBITaxon_115543 a rdfs:Class ;
  rdfs:label "Parasporobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000547 a rdfs:Class ;
  rdfs:label "expansion of Kingella in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Kingella up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000365 a rdfs:Class ;
  rdfs:label "expansion of Providencia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Providencia is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:OHMI_0000784 a rdfs:Class ;
  rdfs:label "depletion of Eubacterium xylanophilum in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Eubacterium xylanophilum down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000126 a rdfs:Class ;
  rdfs:label "depletion of Eubacterium ventriosum in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Eubacterium ventriosum is decreased." ;
  rdfs:subClassOf obo:OHMI_0000311 .

obo:OHMI_0000344 a rdfs:Class ;
  rdfs:label "human-urine microbiome interaction"@en ;
  rdfs:comment "An interaction between human and urine microbiome." ;
  rdfs:subClassOf obo:OHMI_0000019 .

obo:OHMI_0000442 a rdfs:Class ;
  rdfs:label "expansion of C. adipataccumulans in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Catenisphaera adipataccumulans is increased." ;
  rdfs:subClassOf obo:OHMI_0000374 .

obo:OHMI_0000472 a rdfs:Class ;
  rdfs:label "obsolete beta diversity"@en ;
  rdfs:comment "the ratio between regional and local species diversity" .

obo:NCBITaxon_33870 a rdfs:Class ;
  rdfs:label "Coriobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_84107 .

obo:OHMI_0000195 a rdfs:Class ;
  rdfs:label "mouse-microbiome interaction"@en ;
  rdfs:comment "A host-microbiome interaction where the host is musculus." ;
  rdfs:subClassOf obo:OHMI_0000001 .

obo:OHMI_0000429 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides sp. in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroides sp. is increased." ;
  rdfs:subClassOf obo:OHMI_0000333 .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role"@en ;
  rdfs:comment "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:NCBITaxon_995019 a rdfs:Class ;
  rdfs:label "Sutterellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_80840 .

obo:OHMI_0000236 a rdfs:Class ;
  rdfs:label "depletion of Treponema maltophilum in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity microbiome interaction that shows an decrease of Treponema maltophilum in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:PATO_0002003 a rdfs:Class ;
  rdfs:label "population quality" ;
  rdfs:comment "A quality that inheres in an entire population or part of a population." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OHMI_0000832 a rdfs:Class ;
  rdfs:label "depletion of Mollicutes in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Mollicutes down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000402 a rdfs:Class ;
  rdfs:label "expansion of Shigella in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Shigella is increased." ;
  rdfs:subClassOf obo:OHMI_0000349 .

obo:OHMI_0000902 a rdfs:Class ;
  rdfs:label "expansion of Campylobacteraceae in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Campylobacteraceae up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_28050 a rdfs:Class ;
  rdfs:label "Lachnospira" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_84999 a rdfs:Class ;
  rdfs:label "Coriobacteriales" ;
  rdfs:subClassOf obo:NCBITaxon_84998 .

obo:NCBITaxon_65402 a rdfs:Class ;
  rdfs:label "Acidaminobacter" ;
  rdfs:subClassOf obo:NCBITaxon_3082720 .

obo:NCBITaxon_186806 a rdfs:Class ;
  rdfs:label "Eubacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_186802 .

obo:NCBITaxon_622 a rdfs:Class ;
  rdfs:label "Shigella dysenteriae" ;
  rdfs:subClassOf obo:NCBITaxon_620 .

obo:OHMI_0000047 a rdfs:Class ;
  rdfs:label "rat-microbiome interaction"@en ;
  rdfs:comment "A host-microbiome interaction where the host is rattus." ;
  rdfs:subClassOf obo:OHMI_0000001 .

obo:NCBITaxon_158 a rdfs:Class ;
  rdfs:label "Treponema denticola"@en ;
  rdfs:subClassOf obo:NCBITaxon_157 .

obo:OHMI_0000640 a rdfs:Class ;
  rdfs:label "expansion of Moraxella in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Moraxella up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:NCBITaxon_1392389 a rdfs:Class ;
  rdfs:label "Intestinimonas" ;
  rdfs:subClassOf obo:NCBITaxon_538999 .

obo:OHMI_0000011 a rdfs:Class ;
  rdfs:label "interaction between microbiome and host immune system"@en ;
  rdfs:comment "A host-microbiome interaction where the microbiome interacts with the host immune system" ;
  rdfs:subClassOf obo:OHMI_0000001 .

obo:OHMI_0000715 a rdfs:Class ;
  rdfs:label "expansion of Enterocloster citroniae  in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Enterocloster citroniae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000434 a rdfs:Class ;
  rdfs:label "expansion of H. ducreyi in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where [Haemophilus] ducreyi is increased." ;
  rdfs:subClassOf obo:OHMI_0000371 .

obo:OHMI_0000428 a rdfs:Class ;
  rdfs:label "expansion of Clostridium sp. cp01.19 in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Clostridium sp. cp01.19 is increased." ;
  rdfs:subClassOf obo:OHMI_0000302 .

obo:GO_0008150 a rdfs:Class ;
  rdfs:label "biological_process" ;
  rdfs:comment "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OHMI_0000821 a rdfs:Class ;
  rdfs:label "depletion of Dorea in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Dorea down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000203 a rdfs:Class ;
  rdfs:label "arthritis mouse-gut microbiome interaction" ;
  rdfs:comment "A musculus gut-microbiome interaction that is associated with arthritis" ;
  rdfs:subClassOf obo:OHMI_0000196 .

obo:OBI_0000838 a rdfs:Class ;
  rdfs:label "material maintenance" ;
  rdfs:comment "a process with that achieves the objective to maintain some or all of the characteristics of an input material over time" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OHMI_0000298 a rdfs:Class ;
  rdfs:label "expansion of Moniliophthora in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Moniliophthora is increased." ;
  rdfs:subClassOf obo:OHMI_0000286 .

obo:NCBITaxon_246198 a rdfs:Class ;
  rdfs:label "Prevotella intermedia 17" ;
  rdfs:subClassOf obo:NCBITaxon_28131 .

obo:OHMI_0000810 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Prevotella down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_85025 a rdfs:Class ;
  rdfs:label "Nocardiaceae" ;
  rdfs:subClassOf obo:NCBITaxon_85007 .

obo:OHMI_0000808 a rdfs:Class ;
  rdfs:label "depletion of Haemophilus parainfluenzae T3T1 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Haemophilus parainfluenzae T3T1 down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000175 a rdfs:Class ;
  rdfs:label "expansion of Paraprevotella in AS  rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with ankylosing spondylitis(AS) that shows an expansion of Paraprevotella in rattus with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000110 .

obo:PATO_0001019 a rdfs:Class ;
  rdfs:label "mass density" ;
  rdfs:comment "A physical quality which inheres in a bearer by virtue of some influence is exerted by the bearer's mass per unit size." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:NCBITaxon_13687 a rdfs:Class ;
  rdfs:label "Sphingomonas" ;
  rdfs:subClassOf obo:NCBITaxon_41297 .

obo:OHMI_0000407 a rdfs:Class ;
  rdfs:label "expansion of C. Portiera in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Candidatus Portiera is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:OHMI_0000231 a rdfs:Class ;
  rdfs:label "expansion of Atopobium sp. in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of rare taxa,Atopobium sp. in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:OHMI_0000777 a rdfs:Class ;
  rdfs:label "expansion of Lentisphaerota in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Lentisphaerota up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_5140 a rdfs:Class ;
  rdfs:label "Neurospora" ;
  rdfs:subClassOf obo:NCBITaxon_716546 .

obo:OHMI_0000735 a rdfs:Class ;
  rdfs:label "expansion of Intestinimonas in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Intestinimonas up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000720 a rdfs:Class ;
  rdfs:label "expansion of Escherichia in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Escherichia up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_8353 a rdfs:Class ;
  rdfs:label "Xenopus <genus>" ;
  rdfs:subClassOf obo:NCBITaxon_8342 .

obo:OHMI_0000643 a rdfs:Class ;
  rdfs:label "expansion of Streptococcus in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Streptococcus up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OBI_0001271 a rdfs:Class ;
  rdfs:label "RNA-seq assay" ;
  rdfs:comment "An transcription profiling assay that determines an RNA sequence by analyzing the transcibed regions of the genome and or to quantitate transcript abundance." ;
  rdfs:subClassOf obo:OBI_0000424 , obo:OBI_0600047 .

obo:NCBITaxon_539 a rdfs:Class ;
  rdfs:label "Eikenella corrodens" ;
  rdfs:subClassOf obo:NCBITaxon_538 .

obo:OHMI_0000163 a rdfs:Class ;
  rdfs:label "expansion of Firmicutes in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an expansion of Firmicutes in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000122 .

obo:NCBITaxon_84521 a rdfs:Class ;
  rdfs:label "Dolosicoccus paucivorans" ;
  rdfs:subClassOf obo:NCBITaxon_186827 .

obo:OBI_0000131 a rdfs:Class ;
  rdfs:label "molecular feature identification objective"@en ;
  rdfs:comment "Molecular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features of a biological system, e.g. expression profiling, copy number of molecular components, epigenetic modifications."@en ;
  rdfs:subClassOf obo:OBI_0000015 .

obo:DOID_10155 a rdfs:Class ;
  rdfs:label "intestinal cancer" ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the intestine." ;
  rdfs:subClassOf obo:DOID_3119 , obo:DOID_5295 .

obo:NCBITaxon_2717 a rdfs:Class ;
  rdfs:label "Cardiobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OBI_0600014 a rdfs:Class ;
  rdfs:label "material component separation"@en ;
  rdfs:comment "a material processing in which components of an input material become segregated in space"@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:DOID_10534 a rdfs:Class ;
  rdfs:label "stomach cancer" ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the stomach." ;
  rdfs:subClassOf obo:DOID_3119 .

obo:OHMI_0000083 a rdfs:Class ;
  rdfs:label "RA human oral cavity microbiome interaction"@en ;
  rdfs:comment "A human oral cavity microbiome interaction that is associated with rheumatoid arthritis (RA)." ;
  rdfs:subClassOf obo:OHMI_0000036 .

obo:IAO_8000013 a rdfs:Class ;
  rdfs:label "reasoned ontology module"@en ;
  rdfs:comment "An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/reason> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:NCBITaxon_838 a rdfs:Class ;
  rdfs:label "Prevotella" ;
  rdfs:subClassOf obo:NCBITaxon_171552 .

obo:NCBITaxon_90370 a rdfs:Class ;
  rdfs:label "Salmonella enterica subsp. enterica serovar Typhi" ;
  rdfs:subClassOf obo:NCBITaxon_59201 .

obo:OHMI_0000382 a rdfs:Class ;
  rdfs:label "depletion of Blautia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Blautia is decreased." ;
  rdfs:subClassOf obo:OHMI_0000346 .

obo:OHMI_0000673 a rdfs:Class ;
  rdfs:label "bacterial change in gut of MDD patient compared to healthy human" ;
  rdfs:comment "MDD human gut microbiome interaction that shows an change of bacteria in patients with MDD compared to healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000672 .

obo:OHMI_0000072 a rdfs:Class ;
  rdfs:label "expansion of Prevotella in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an expansion of Prevotella in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000211 .

obo:OHMI_0000815 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacterium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Faecalibacterium down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_74426 a rdfs:Class ;
  rdfs:label "Collinsella aerofaciens" ;
  rdfs:subClassOf obo:NCBITaxon_102106 .

obo:OBI_0001051 a rdfs:Class ;
  rdfs:label "DNA extract" ;
  rdfs:comment "The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas." ;
  rdfs:subClassOf obo:OBI_0001010 .

obo:OHMI_0000130 a rdfs:Class ;
  rdfs:label "expansion of Escherichia coli EPEC 32/73 in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Escherichia coli EPEC32/73 in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:PCO_0000077 a rdfs:Class ;
  rdfs:label "plant density"@en ;
  rdfs:subClassOf obo:PATO_0001019 .

obo:UBERON_0004921 a rdfs:Class ;
  rdfs:label "subdivision of digestive tract" ;
  rdfs:comment "A proximal-distal subdivision of the digestive tract." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:NCBITaxon_404402 a rdfs:Class ;
  rdfs:label "Howardella" ;
  rdfs:subClassOf obo:NCBITaxon_538999 .

obo:OHMI_0000708 a rdfs:Class ;
  rdfs:label "expansion of Escherichia coli in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Escherichia coli up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000459 a rdfs:Class ;
  rdfs:label "expansion of Lachnospiraceae bacterium in RA human gut"@en ;
  rdfs:comment "A RA human-gut microbiome interaction where Lachnospiraceae bacterium is increased." ;
  rdfs:subClassOf obo:OHMI_0000070 .

obo:NCBITaxon_109326 a rdfs:Class ;
  rdfs:label "Anaerovorax" ;
  rdfs:subClassOf obo:NCBITaxon_543314 .

obo:NCBITaxon_1570339 a rdfs:Class ;
  rdfs:label "Peptoniphilaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1239 .

obo:OHMI_0000307 a rdfs:Class ;
  rdfs:label "depletion of Cronobacter in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Cronobacter is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:INO_0000002 a rdfs:Class ;
  rdfs:label "interaction" ;
  rdfs:comment "Interaction is a processual entity that has two or more participants (i.e., interactors) that have an effect upon one another. "@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:DRON_00000005 a rdfs:Class ;
  rdfs:label "drug product"@en ;
  rdfs:comment "a material entity (1) containing at least one scattered molecular aggregate as part that is the bearer of an active ingredient role and (2) that is itself the bearer of a clinical drug role"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0000165 a rdfs:Class ;
  rdfs:label "mouth" ;
  rdfs:comment "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/issues/661> ;
  rdfs:subClassOf obo:UBERON_0004921 .

obo:NCBITaxon_1385 a rdfs:Class ;
  rdfs:label "Bacillales" ;
  rdfs:subClassOf obo:NCBITaxon_91061 .

obo:OHMI_0000247 a rdfs:Class ;
  rdfs:label "expansion of Anaerolineales in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Anaerolineales in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:OHMI_0000592 a rdfs:Class ;
  rdfs:label "depletion of Actinobacteria in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Actinobacteria down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000445 a rdfs:Class ;
  rdfs:label "expansion of C. rodentium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Citrobacter rodentium is increased." ;
  rdfs:subClassOf obo:OHMI_0000349 .

obo:OHMI_0000405 a rdfs:Class ;
  rdfs:label "expansion of Mycobacterium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Mycobacterium is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_40545 a rdfs:Class ;
  rdfs:label "Sutterella wadsworthensis" ;
  rdfs:subClassOf obo:NCBITaxon_40544 .

obo:OHMI_0000418 a rdfs:Class ;
  rdfs:label "depletion of Bacteroides in RA human gut compared to fibromyalgia patients"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Bacteroides in patients with RA compared with fibromyalgia patients." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:NCBITaxon_2810281 a rdfs:Class ;
  rdfs:label "Turicibacteraceae" ;
  rdfs:subClassOf obo:NCBITaxon_526525 .

obo:OHMI_0000738 a rdfs:Class ;
  rdfs:label "expansion of Pseudomonas in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Pseudomonas up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000300 a rdfs:Class ;
  rdfs:label "expansion of Collinsella in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Collinsella is increased." ;
  rdfs:subClassOf obo:OHMI_0000376 .

obo:NCBITaxon_2732514 a rdfs:Class ;
  rdfs:label "Revtraviricetes" ;
  rdfs:subClassOf obo:NCBITaxon_2559587 .

obo:NCBITaxon_5476 a rdfs:Class ;
  rdfs:label "Candida albicans" ;
  rdfs:subClassOf obo:NCBITaxon_5475 .

obo:OHMI_0000320 a rdfs:Class ;
  rdfs:label "depletion of L. bovis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Lachnobacterium bovis is decreased." ;
  rdfs:subClassOf obo:OHMI_0000346 .

obo:NCBITaxon_186817 a rdfs:Class ;
  rdfs:label "Bacillaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1385 .

obo:OHMI_0000725 a rdfs:Class ;
  rdfs:label "expansion of Deinococcus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Deinococcus up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000141 a rdfs:Class ;
  rdfs:label "expansion of Acetanaerobacterium in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of rare taxa,Acetanaerobacterium in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity"@en ;
  rdfs:comment "A generically dependent continuant that is about some thing."@en ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:OHMI_0000022 a rdfs:Class ;
  rdfs:label "human gut microbiome interaction in bowel syndrome"@en ;
  rdfs:comment "A human-gut microbiome interaction that is associated with bowel syndrome." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:OHMI_0000067 a rdfs:Class ;
  rdfs:label "diarrheal patient-gut microbiome interaction"@en ;
  rdfs:comment "A human gut-microbiome interaction that is associated with the diarrhea disease" ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:NCBITaxon_470 a rdfs:Class ;
  rdfs:label "Acinetobacter baumannii" ;
  rdfs:subClassOf obo:NCBITaxon_469 .

obo:OHMI_0000659 a rdfs:Class ;
  rdfs:label "depletion of Propionibacterium in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Propionibacterium down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:NCBITaxon_8342 a rdfs:Class ;
  rdfs:label "Anura" ;
  rdfs:subClassOf obo:NCBITaxon_32523 .

obo:OHMI_0000119 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidaceae in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Bacteroidaceae in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000117 .

obo:OHMI_0000124 a rdfs:Class ;
  rdfs:label "depletion of Photobacterium in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Photobacterium in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000123 .

obo:NCBITaxon_2559587 a rdfs:Class ;
  rdfs:label "Riboviria" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:NCBITaxon_3085642 a rdfs:Class ;
  rdfs:label "Butyricicoccaceae" ;
  rdfs:subClassOf obo:NCBITaxon_186802 .

obo:OHMI_0000152 a rdfs:Class ;
  rdfs:label "PsA human-gut microbiome interaction"@en ;
  rdfs:comment "A human gut-microbiome interaction that is associated with  juvenile psoriatic arthritis(PsA)." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:UBERON_0000064 a rdfs:Class ;
  rdfs:label "organ part" ;
  rdfs:comment "A multicellular structure that is a part of an organ." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:NCBITaxon_1313 a rdfs:Class ;
  rdfs:label "Streptococcus pneumoniae" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:OHMI_0000726 a rdfs:Class ;
  rdfs:label "expansion of Enterococcus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Enterococcus up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_472977 a rdfs:Class ;
  rdfs:label "Natronobacillus" ;
  rdfs:subClassOf obo:NCBITaxon_186817 .

obo:OBI_0000725 a rdfs:Class ;
  rdfs:label "host role" ;
  rdfs:comment "host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role" ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OHMI_0000199 a rdfs:Class ;
  rdfs:label "expansion of Ruminococcaceae in SLE  mouse gut"@en ;
  rdfs:comment "An association of musculus gut microbiota with system lupus erythematosus(SLE) that shows an expansion of Ruminococcaceae in musculus with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000200 .

obo:PATO_0001995 a rdfs:Class ;
  rdfs:label "organismal quality" ;
  rdfs:comment "A quality that inheres in an entire organism or part of an organism." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OBI_0000740 a rdfs:Class ;
  rdfs:label "material sample role" ;
  rdfs:comment "A material sample role is a specimen role borne by a material entity that is the output of a material sampling process." ;
  rdfs:subClassOf obo:OBI_0000112 .

obo:OBI_0001912 a rdfs:Class ;
  rdfs:label "cell freezing medium"@en ;
  rdfs:comment "A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles. " ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OHMI_0000536 a rdfs:Class ;
  rdfs:label "expansion of Butyrivibrio in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Butyrivibrio up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_7742 a rdfs:Class ;
  rdfs:label "Vertebrata <vertebrates>" ;
  rdfs:subClassOf obo:NCBITaxon_33213 .

obo:OHMI_0000205 a rdfs:Class ;
  rdfs:label "Actinobacteria<class> depletion in arthritis mouse gut"@en ;
  rdfs:comment "An association of musculus gut microbiota with arthritis  that shows a depleted quantity of Actinobacteria<class> in musculus with arthritis compared with healty controls." ;
  rdfs:subClassOf obo:OHMI_0000203 .

obo:NCBITaxon_197562 a rdfs:Class ;
  rdfs:label "Pancrustacea" ;
  rdfs:subClassOf obo:NCBITaxon_1206794 .

obo:OHMI_0000906 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidetes in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroidetes up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:ENVO_00010483 a rdfs:Class ;
  rdfs:label "environmental material" ;
  rdfs:comment "A portion of environmental material is a fiat object which forms the medium or part of the medium of an environmental system." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OHMI_0000242 a rdfs:Class ;
  rdfs:label "expansion of Fusobacterium in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity  microbiome interaction that shows an expansion of Fusobacterium  in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:OHMI_0000826 a rdfs:Class ;
  rdfs:label "depletion of Lachnospiraceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Lachnospiraceae down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_1766253 a rdfs:Class ;
  rdfs:label "Agathobacter" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000788 a rdfs:Class ;
  rdfs:label "depletion of Phocaeicola plebeius in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Phocaeicola plebeius down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:DOID_7147 a rdfs:Class ;
  rdfs:label "ankylosing spondylitis" ;
  rdfs:comment "A bone inflammation disease that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage." ;
  rdfs:subClassOf obo:DOID_1575 , obo:DOID_3342 .

obo:IAO_8000006 a rdfs:Class ;
  rdfs:label "subset ontology module"@en ;
  rdfs:comment "An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/filter> , <http://www.geneontology.org/page/go-slim-and-subset-guide> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:NCBITaxon_649776 a rdfs:Class ;
  rdfs:label "Synergistales" ;
  rdfs:subClassOf obo:NCBITaxon_3384194 .

obo:OHMI_0000632 a rdfs:Class ;
  rdfs:label "depletion of Firmicutes in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Firmicutes down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000316 a rdfs:Class ;
  rdfs:label "depletion of B.intestinalis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroides intestinalis is decreased." ;
  rdfs:subClassOf obo:OHMI_0000352 .

obo:OHMI_0000113 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidetes in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an expansion of Bacteroidetes in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000053 .

obo:OHMI_0000799 a rdfs:Class ;
  rdfs:label "depletion of Eubacterium sp. CAG:202 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Eubacterium sp. CAG:202 down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_538999 a rdfs:Class ;
  rdfs:label "Eubacteriales incertae sedis" ;
  rdfs:subClassOf obo:NCBITaxon_186802 .

obo:UBERON_0000477 a rdfs:Class ;
  rdfs:label "anatomical cluster" ;
  rdfs:comment "Anatomical group that has its parts adjacent to one another." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:GO_0051704 a rdfs:Class ;
  rdfs:label "multi-organism process" ;
  rdfs:comment "A biological process which involves another organism of the same or different species." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:OHMI_0000058 a rdfs:Class ;
  rdfs:label "depletion of Citrobacter in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Citrobacter is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000557 a rdfs:Class ;
  rdfs:label "expansion of Campylobacteriaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Campylobacteriaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_91994 a rdfs:Class ;
  rdfs:label "unclassified Staphylococcus" ;
  rdfs:subClassOf obo:NCBITaxon_1279 .

obo:NCBITaxon_1847 a rdfs:Class ;
  rdfs:label "Pseudonocardia"@en ;
  rdfs:subClassOf obo:NCBITaxon_2070 .

obo:OHMI_0000348 a rdf:Property ;
  rdfs:label "microbe susceptibly expanded in respiratory airway of human with disease"@en ;
  rdfs:comment "An object property that represents the susceptible increase (compared to healthy control) of the population of a microbe in the respiratory airway of a human with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000056 .

obo:OHMI_0000167 a rdfs:Class ;
  rdfs:label "expansion of Candida albicans in PsA human oral cavity"@en ;
  rdfs:comment "An association of human oral cavity microbiota with psoriatic arthritis(PsA) that shows an expansion of Candida albicans in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000166 .

obo:OHMI_0000573 a rdfs:Class ;
  rdfs:label "depletion of Nakamurellaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Nakamurellaceae down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_172042 a rdfs:Class ;
  rdfs:label "Rothia aeria" ;
  rdfs:subClassOf obo:NCBITaxon_32207 .

obo:OHMI_0000326 a rdfs:Class ;
  rdfs:label "depletion of M. hypermegale in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Megamonas hypermegale is decreased." ;
  rdfs:subClassOf obo:OHMI_0000356 .

obo:DOID_0050686 a rdfs:Class ;
  rdfs:label "organ system cancer" ;
  rdfs:comment "A cancer that is classified based on the organ it starts in." ;
  rdfs:subClassOf obo:DOID_162 .

obo:OHMI_0000438 a rdfs:Class ;
  rdfs:label "depletion of Bifidobacterium bifidum in RA human gut compared to fibromyalgia patients"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Bifidobacterium bifidum in patients with RA compared with fibromyalgia patients." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000687 a rdfs:Class ;
  rdfs:label "expansion of Bilophila wadsworthia in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bilophila wadsworthia up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000424 a rdfs:Class ;
  rdfs:label "expansion of P. stomatis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Peptostreptococcus stomatis is increased." ;
  rdfs:subClassOf obo:OHMI_0000288 .

obo:NCBITaxon_2115 a rdfs:Class ;
  rdfs:label "Mycoplasmopsis fermentans" ;
  rdfs:subClassOf obo:NCBITaxon_544448 .

obo:NCBITaxon_31977 a rdfs:Class ;
  rdfs:label "Veillonellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_909932 .

obo:OHMI_0000343 a rdfs:Class ;
  rdfs:label "expansion of B. xylanisolvens in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroides xylanisolvens is increased." ;
  rdfs:subClassOf obo:OHMI_0000333 .

obo:OHMI_0000746 a rdfs:Class ;
  rdfs:label "expansion of Actinomyces in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Actinomyces up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000264 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides plebeius in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Bacteroides plebeius in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000256 .

obo:NCBITaxon_183710 a rdfs:Class ;
  rdfs:label "Deinococcaceae" ;
  rdfs:subClassOf obo:NCBITaxon_3384194 .

obo:OHMI_0000394 a rdfs:Class ;
  rdfs:label "depletion of Streptococcus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Streptococcus is decreased." ;
  rdfs:subClassOf obo:OHMI_0000356 .

obo:BFO_0000001 a rdfs:Class ;
  rdfs:label "entity"@en .

obo:OHMI_0000804 a rdfs:Class ;
  rdfs:label "depletion of Bacteroidaceae bacterium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroidaceae bacterium down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000730 a rdfs:Class ;
  rdfs:label "expansion of Alistipes in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Alistipes up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000539 a rdfs:Class ;
  rdfs:label "expansion of Anaerosporobacter in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Anaerosporobacter up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000275 a rdfs:Class ;
  rdfs:label "depletion of Coprococcus in PsA human gut"@en ;
  rdfs:comment "a PsA human-gut microbiome interaction that shows an decrease of Coprococcus in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000152 .

obo:NCBITaxon_28135 a rdfs:Class ;
  rdfs:label "Segatella oris" ;
  rdfs:subClassOf obo:NCBITaxon_2974251 .

obo:OHMI_0000654 a rdfs:Class ;
  rdfs:label "depletion of Bifidobacterium in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:NCBITaxon_9606 a rdfs:Class ;
  rdfs:label "Homo sapiens" ;
  rdfs:subClassOf obo:NCBITaxon_314146 .

obo:OHMI_0000037 a rdfs:Class ;
  rdfs:label "expansion of Gordonibacter pamelaeae in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Gordonibacter pamelaeae in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000085 .

obo:OHMI_0000489 a rdfs:Class ;
  rdfs:label "COPD human respiratory airway microbiome interaction"@en ;
  rdfs:comment "A human respiratory airway microbiome interaction where he human is diseased with Chronic obstructive pulmonary disease (COPD)" ;
  rdfs:subClassOf obo:OHMI_0000077 .

obo:OHMI_0000849 a rdfs:Class ;
  rdfs:label "expansion of Megasphaera in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Megasphaera up-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:OHMI_0000579 a rdfs:Class ;
  rdfs:label "depletion of Citrobacter in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Citrobacter down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_203691 a rdfs:Class ;
  rdfs:label "Spirochaetota" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:OHMI_0000766 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Lactobacillaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000204 a rdfs:Class ;
  rdfs:label "expansion of Prevotella copri in arthritis mouse gut"@en ;
  rdfs:comment "An association of musuculus gut microbiota with arthritis that shows an expansion of Prevotella copri in musuculus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000203 .

obo:OHMI_0000149 a rdfs:Class ;
  rdfs:label "depletion of Dialister in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Dialister in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:OHMI_0000427 a rdfs:Class ;
  rdfs:label "expansion of D. paucivorans in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Dolosicoccus paucivorans is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_1962667 a rdfs:Class ;
  rdfs:label "Nannocystis sp." ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:OBI_0002444 a rdfs:Class ;
  rdfs:label "measurand role"@en ;
  rdfs:comment "A role borne by a material entity and realized in an assay which achieves the objective to measure the magnitude/concentration/amount of the measurand in the entity bearing evaluant role." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:NCBITaxon_590 a rdfs:Class ;
  rdfs:label "Salmonella" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:OHMI_0000478 a rdfs:Class ;
  rdfs:label "host microbiome restoration by microbiota transplantation"@en ;
  rdfs:comment "host microbiome restoration through the transplantation of a microbiota into the host" ;
  rdfs:subClassOf obo:OHMI_0000475 .

obo:UBERON_0004908 a rdfs:Class ;
  rdfs:label "upper digestive tract" ;
  rdfs:comment "The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum." ;
  rdfs:subClassOf obo:UBERON_0004921 .

obo:NCBITaxon_459786 a rdfs:Class ;
  rdfs:label "Oscillibacter" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:CMO_0002102 a rdfs:Class ;
  rdfs:label "serum immunoglobulin G level" ;
  rdfs:comment "The amount in a specified sample of serum of one or more types of immunoglobulin G (IgG), the most abundant class of antibodies found in blood serum and lymph. IgG antibodies are active against bacteria, fungi, viruses, and foreign particles, and trigger action of the complement system." ;
  rdfs:subClassOf obo:CMO_0001276 .

obo:NCBITaxon_186801 a rdfs:Class ;
  rdfs:label "Clostridia" ;
  rdfs:subClassOf obo:NCBITaxon_1239 .

obo:OHMI_0000637 a rdfs:Class ;
  rdfs:label "expansion of Proteobacteria in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Proteobacteria up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:NCBITaxon_76777 a rdfs:Class ;
  rdfs:label "Malassezia sympodialis" ;
  rdfs:subClassOf obo:NCBITaxon_55193 .

obo:OHMI_0000838 a rdfs:Class ;
  rdfs:label "expansion of Bilophila in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Bilophila up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_5204 a rdfs:Class ;
  rdfs:label "Basidiomycota" ;
  rdfs:subClassOf obo:NCBITaxon_451864 .

obo:NCBITaxon_28901 a rdfs:Class ;
  rdfs:label "Salmonella enterica" ;
  rdfs:subClassOf obo:NCBITaxon_590 .

obo:OHMI_0000146 a rdfs:Class ;
  rdfs:label "depletion of Odoribacter in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Odoribacter in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:NCBITaxon_203491 a rdfs:Class ;
  rdfs:label "Fusobacteriales" ;
  rdfs:subClassOf obo:NCBITaxon_32066 .

obo:OHMI_0000922 a rdfs:Class ;
  rdfs:label "expansion of Eggerthellaceae in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Eggerthellaceae up-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:NCBITaxon_1378 a rdfs:Class ;
  rdfs:label "Gemella" ;
  rdfs:subClassOf obo:NCBITaxon_1385 .

obo:OHMI_0000684 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides eggerthii in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroides eggerthii up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000819 a rdfs:Class ;
  rdfs:label "depletion of Sutterella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Sutterella down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:ENVO_01000739 a rdfs:Class ;
  rdfs:label "habitat"@en ;
  rdfs:comment "An environmental system which can sustain and allow the growth of an ecological population." ;
  rdfs:subClassOf obo:ENVO_01001110 .

obo:OHMI_0000029 a rdfs:Class ;
  rdfs:label "RA human-gut microbiome interaction"@en ;
  rdfs:comment "A human gut-microbiome interaction that is associated with rheumatoid arthritis (RA)." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:NCBITaxon_33090 a rdfs:Class ;
  rdfs:label "Viridiplantae" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:BFO_0000004 a rdfs:Class ;
  rdfs:label "independent continuant"@en ;
  rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:OHMI_0000157 a rdfs:Class ;
  rdfs:label "depletion of Parabacteroides in PsA human gut"@en ;
  rdfs:comment "a PsA human-gut microbiome interaction that shows an decrease of Parabacteroides in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000152 .

obo:OHMI_0000190 a rdfs:Class ;
  rdfs:label "expansion of E. coli in arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Escherichia coli in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:OHMI_0000015 a rdfs:Class ;
  rdfs:label "microbiome in human oral"@en ;
  rdfs:comment "a human microbiome that is located in a human oral system" ;
  rdfs:subClassOf obo:OHMI_0000002 .

obo:NCBITaxon_33033 a rdfs:Class ;
  rdfs:label "Parvimonas micra" ;
  rdfs:subClassOf obo:NCBITaxon_543311 .

obo:OHMI_0000332 a rdfs:Class ;
  rdfs:label "depletion of Anoxybacillus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Anoxybacillus is decreased." ;
  rdfs:subClassOf obo:OHMI_0000356 .

obo:MONDO_0019437 a rdfs:Class ;
  rdfs:label "enthesitis-related juvenile idiopathic arthritis" ;
  rdfs:comment "Enthesitis-related juvenile idiopathic arthritis is a subtype of juvenile idiopathic arthritis that is characterized by both arthritis and inflammation of an enthesitis site (the point at which a ligament, tendon, or joint capsule attaches to the bone). Signs and symptoms generally develop in late childhood or early adolescence and include pain, tenderness, and swelling in joints and at the enthesis. The knee and the back of the ankle (at the Achilles tendon) are the most commonly affected parts of the body. The underlying cause of enthesitis-related juvenile idiopathic arthritis is currently unknown (idiopathic). It is very rare for more than one member of a family to have juvenile arthritis; however, research suggests that having a family member with juvenile arthritis or any autoimmune disease may increase the risk of having juvenile arthritis, in general. Treatment usually involves different types of medications to help manage symptoms and/or physical therapy ." ;
  rdfs:seeAlso <https://rarediseases.info.nih.gov/diseases/10969/enthesitis-related-juvenile-idiopathic-arthritis> ;
  rdfs:subClassOf obo:DOID_676 .

obo:OHMI_0000004 a rdfs:Class ;
  rdfs:label "mouse microbiome"@en ;
  rdfs:comment "A microbiome located in a mouse body" ;
  rdfs:subClassOf obo:OHMI_0000003 .

obo:OHMI_0000063 a rdfs:Class ;
  rdfs:label "expansion of Prevotella intermedia in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of rare taxa,Prevotella intermedia in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000178 .

obo:NCBITaxon_543311 a rdfs:Class ;
  rdfs:label "Parvimonas" ;
  rdfs:subClassOf obo:NCBITaxon_1570339 .

obo:OHMI_0000596 a rdfs:Class ;
  rdfs:label "depletion of Epsilonproteobacteria in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Epsilonproteobacteria down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:IAO_8000011 a rdfs:Class ;
  rdfs:label "external import ontology module"@en ;
  rdfs:comment "An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach."@en ;
  rdfs:subClassOf obo:IAO_8000005 .

obo:OHMI_0000871 a rdfs:Class ;
  rdfs:label "depletion of Gordonibacter in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Gordonibacter down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_116085 a rdfs:Class ;
  rdfs:label "Coprococcus catus" ;
  rdfs:subClassOf obo:NCBITaxon_33042 .

obo:NCBITaxon_1129771 a rdfs:Class ;
  rdfs:label "Leptotrichiaceae" ;
  rdfs:subClassOf obo:NCBITaxon_203491 .

obo:OBI_0000424 a rdfs:Class ;
  rdfs:label "transcription profiling assay" ;
  rdfs:comment "An assay that determines gene expression and transcription activity using ribonucleic acids collected from a material entity." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OHMI_0000291 a rdfs:Class ;
  rdfs:label "expansion of Malassezia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Malassezia is increased." ;
  rdfs:subClassOf obo:OHMI_0000286 .

obo:NCBITaxon_767031 a rdfs:Class ;
  rdfs:label "Prevotella denticola F0289" ;
  rdfs:subClassOf obo:NCBITaxon_838 .

obo:NCBITaxon_170 a rdfs:Class ;
  rdfs:label "Leptospiraceae" ;
  rdfs:subClassOf obo:NCBITaxon_203692 .

obo:NCBITaxon_40324 a rdfs:Class ;
  rdfs:label "Stenotrophomonas maltophilia" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OHMI_0000795 a rdfs:Class ;
  rdfs:label "depletion of Clostridium sp. CAG:217 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Clostridium sp. CAG:217 down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:IAO_0000007 a rdfs:Class ;
  rdfs:label "action specification"@en ;
  rdfs:comment "a directive information entity that describes an action the bearer will take"@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:NCBITaxon_766165 a rdfs:Class ;
  rdfs:label "Escherichia coli EPEC 32/73" ;
  rdfs:subClassOf obo:NCBITaxon_562 .

obo:OHMI_0000156 a rdfs:Class ;
  rdfs:label "depletion of Verrucomicrobia in PsA human gut"@en ;
  rdfs:comment "a PsA human-gut microbiome interaction that shows an decrease of Verrucomicrobia in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000152 .

obo:OHMI_0000568 a rdfs:Class ;
  rdfs:label "expansion of Pseudomonas in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Pseudomonas up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OBI_0000744 a rdfs:Class ;
  rdfs:label "material sampling process" ;
  rdfs:comment "A specimen gathering process with the objective to obtain a specimen that is representative of the input material entity" ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:OHMI_0000168 a rdfs:Class ;
  rdfs:label "depletion of Malassezia restricta in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an decrease of Malassezia restricta in patients with  PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000122 .

obo:OHMI_0000504 a rdfs:Class ;
  rdfs:label "expansion of Staphylococcus aureus in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Staphylococcus aureus up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_171550 a rdfs:Class ;
  rdfs:label "Rikenellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_171549 .

obo:OHMI_0000315 a rdfs:Class ;
  rdfs:label "depletion of B. finegoldii in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroides finegoldii is decreased." ;
  rdfs:subClassOf obo:OHMI_0000352 .

obo:NCBITaxon_1437201 a rdfs:Class ;
  rdfs:label "Pentapetalae" ;
  rdfs:subClassOf obo:NCBITaxon_1437183 .

obo:NCBITaxon_971 a rdfs:Class ;
  rdfs:label "Selenomonas ruminantium" ;
  rdfs:subClassOf obo:NCBITaxon_970 .

obo:OHMI_0000449 a rdfs:Class ;
  rdfs:label "expansion of C.hylemonae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where [Clostridium] hylemonae is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:NCBITaxon_328813 a rdfs:Class ;
  rdfs:label "Alistipes onderdonkii" ;
  rdfs:subClassOf obo:NCBITaxon_239759 .

obo:NCBITaxon_72294 a rdfs:Class ;
  rdfs:label "Campylobacteraceae" ;
  rdfs:subClassOf obo:NCBITaxon_213849 .

obo:OHMI_0000095 a rdfs:Class ;
  rdfs:label "rat gut microbiome interaction"@en ;
  rdfs:comment "An interaction between rattus and gut microbiome." ;
  rdfs:subClassOf obo:OHMI_0000047 .

obo:OHMI_0000584 a rdfs:Class ;
  rdfs:label "expansion of Actinobacillus in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Actinobacillus up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_740 a rdfs:Class ;
  rdfs:label "Haemophilus sp."@en ;
  rdfs:subClassOf obo:NCBITaxon_724 .

obo:NCBITaxon_4896 a rdfs:Class ;
  rdfs:label "Schizosaccharomyces pombe" ;
  rdfs:subClassOf obo:NCBITaxon_4890 , obo:OHMI_0000460 .

obo:NCBITaxon_39107 a rdfs:Class ;
  rdfs:label "Murinae" ;
  rdfs:subClassOf obo:NCBITaxon_9989 .

obo:NCBITaxon_375288 a rdfs:Class ;
  rdfs:label "Parabacteroides" ;
  rdfs:subClassOf obo:NCBITaxon_2005525 .

obo:NCBITaxon_33877 a rdfs:Class ;
  rdfs:label "Agromyces" ;
  rdfs:subClassOf obo:NCBITaxon_85023 .

obo:NCBITaxon_1017 a rdfs:Class ;
  rdfs:label "Capnocytophaga gingivalis"@en ;
  rdfs:subClassOf obo:NCBITaxon_1016 .

obo:OBI_0001479 a rdfs:Class ;
  rdfs:label "specimen from organism"@en ;
  rdfs:comment "A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm)." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:NCBITaxon_561 a rdfs:Class ;
  rdfs:label "Escherichia" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:OHMI_0000071 a rdfs:Class ;
  rdfs:label "expansion of Clostridium perfringens in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Clostridium perfringens in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000070 .

obo:OBI_0000423 a rdfs:Class ;
  rdfs:label "extract"@en ;
  rdfs:comment "an extract is a material entity which results from an extraction process"@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:NCBITaxon_408139 a rdfs:Class ;
  rdfs:label "Leptospira kmetyi" ;
  rdfs:subClassOf obo:NCBITaxon_170 .

obo:GO_0044419 a rdfs:Class ;
  rdfs:label "interspecies interaction between organisms" ;
  rdfs:comment "Any process in which an organism has an effect on an organism of a different species." ;
  rdfs:subClassOf obo:GO_0051704 .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process"@en ;
  rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OHMI_0000714 a rdfs:Class ;
  rdfs:label "expansion of Pseudoflavonifractor capillosus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Pseudoflavonifractor capillosus up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000416 a rdfs:Class ;
  rdfs:label "expansion of F. nucleatum in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacterium nucleatum is increased." ;
  rdfs:subClassOf obo:OHMI_0000289 .

obo:NCBITaxon_186650 a rdfs:Class ;
  rdfs:label "Microvirga" ;
  rdfs:subClassOf obo:NCBITaxon_119045 .

obo:OHMI_0000755 a rdfs:Class ;
  rdfs:label "expansion of Parvimonas in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Parvimonas up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000312 a rdfs:Class ;
  rdfs:label "depletion of Anaerovorax in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Anaerovorax is decreased." ;
  rdfs:subClassOf obo:OHMI_0000356 .

obo:NCBITaxon_1717 a rdfs:Class ;
  rdfs:label "Corynebacterium diphtheriae" ;
  rdfs:subClassOf obo:NCBITaxon_1716 .

obo:NCBITaxon_81852 a rdfs:Class ;
  rdfs:label "Enterococcaceae" ;
  rdfs:subClassOf obo:NCBITaxon_186826 .

obo:OHMI_0000676 a rdfs:Class ;
  rdfs:label "bacterial change in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "MDD human gut microbiome interaction that shows an change of bacteria in female patients with MDD compared to healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000672 .

obo:NCBITaxon_33154 a rdfs:Class ;
  rdfs:label "Opisthokonta" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:OHMI_0000882 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides caccae in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroides caccae up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000741 a rdfs:Class ;
  rdfs:label "expansion of Megasphaera in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Megasphaera up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000286 a rdfs:Class ;
  rdfs:label "expansion of Basidiomycota in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Basidiomycota is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_91061 a rdfs:Class ;
  rdfs:label "Bacilli" ;
  rdfs:subClassOf obo:NCBITaxon_1239 .

obo:NCBITaxon_119060 a rdfs:Class ;
  rdfs:label "Burkholderiaceae" ;
  rdfs:subClassOf obo:NCBITaxon_80840 .

obo:OHMI_0000665 a rdfs:Class ;
  rdfs:label "disease stable"@en ;
  rdfs:comment "A process quality in which a disease is in its stable stage." ;
  rdfs:subClassOf obo:PATO_0001236 .

obo:OHMI_0000253 a rdfs:Class ;
  rdfs:label "expansion of Selenomonadales in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Selenomonadales in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000120 .

obo:PCO_0000064 a rdfs:Class ;
  rdfs:label "inverse Simpson diversity index"@en ;
  rdfs:comment "A community species diversity metric that is quantified via the following formula: the sum of squared proportion of species i relative to the total number of species (pi)." ;
  rdfs:subClassOf obo:PCO_0000019 .

obo:NCBITaxon_729 a rdfs:Class ;
  rdfs:label "Haemophilus parainfluenzae" ;
  rdfs:subClassOf obo:NCBITaxon_724 .

obo:OHMI_0000271 a rdfs:Class ;
  rdfs:label "depletion of [Clostridium] clostridioforme in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an decrease of [Clostridium] clostridioforme in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000270 .

obo:OHMI_0000413 a rdfs:Class ;
  rdfs:label "depletion of Blautia coccoides in RA human gut compared to fibromyalgia patients"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Blautia coccoides in patients with RA compared with fibromyalgia patients." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000703 a rdfs:Class ;
  rdfs:label "expansion of Prevotella melaninogenica ATCC25845 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Prevotella melaninogenica ATCC25845 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000762 a rdfs:Class ;
  rdfs:label "expansion of Enterobacteriaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Enterobacteriaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000026 a rdfs:Class ;
  rdfs:label "antibiotics reducing colonization resistance against C. difficile in human gut"@en ;
  rdfs:comment "A human-gut microbiome interaction where antibiotics have significant and long-lasting effects on the intestinal microbiota and consequently reduce colonization resistance against Clostridium difficile." ;
  rdfs:subClassOf obo:OHMI_0000025 .

obo:OHMI_0000123 a rdfs:Class ;
  rdfs:label "depletion of Vibrionaceae in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Vibrionaceae in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:OHMI_0000514 a rdfs:Class ;
  rdfs:label "expansion of Micrococcaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Micrococcaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OBI_0000079 a rdfs:Class ;
  rdfs:label "culture medium"@en ;
  rdfs:comment "a processed material that provides the needed nourishment for microorganisms or cells grown in vitro." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OHMI_0000864 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Prevotella down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000602 a rdfs:Class ;
  rdfs:label "depletion of Slackia in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Slackia down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000387 a rdfs:Class ;
  rdfs:label "expansion of L. bacterium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Lachnospiraceae bacterium is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:OHMI_0000104 a rdfs:Class ;
  rdfs:label "expansion of Veillonellaceae in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of rare taxa,Veillonellaceae in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000099 .

obo:OHMI_0000220 a rdfs:Class ;
  rdfs:label "expansion of Methylobacterium in RA human respiratory airway"@en ;
  rdfs:comment "RA human respiratory airway  microbiome interaction that shows an expansion of Methylobacterium in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000078 .

obo:OHMI_0000258 a rdfs:Class ;
  rdfs:label "expansion of Enterococcaceae in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Enterococcaceae in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000255 .

obo:OHMI_0000927 a rdfs:Class ;
  rdfs:label "depletion of Solobacterium in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Solobacterium down-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:NCBITaxon_357276 a rdfs:Class ;
  rdfs:label "Phocaeicola dorei" ;
  rdfs:subClassOf obo:NCBITaxon_909656 .

obo:OHMI_0000398 a rdfs:Class ;
  rdfs:label "expansion of S. equinus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Streptococcus equinus is increased." ;
  rdfs:subClassOf obo:OHMI_0000367 .

obo:OHMI_0000135 a rdfs:Class ;
  rdfs:label "expansion of Anaerotruncus in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Anaerotruncus in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:UBERON_0000945 a rdfs:Class ;
  rdfs:label "stomach" ;
  rdfs:comment "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." ;
  rdfs:subClassOf obo:UBERON_0004921 , obo:UBERON_0013765 .

obo:OHMI_0000420 a rdfs:Class ;
  rdfs:label "expansion of P. gingivalis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Porphyromonas gingivalis is increased." ;
  rdfs:subClassOf obo:OHMI_0000372 .

obo:NCBITaxon_302911 a rdfs:Class ;
  rdfs:label "Bifidobacterium animalis subsp. lactis" ;
  rdfs:subClassOf obo:NCBITaxon_28025 .

obo:NCBITaxon_88138 a rdfs:Class ;
  rdfs:label "Modestobacter" ;
  rdfs:subClassOf obo:NCBITaxon_85030 .

obo:DOID_162 a rdfs:Class ;
  rdfs:label "cancer" ;
  rdfs:comment "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis." ;
  rdfs:subClassOf obo:DOID_4 .

obo:NCBITaxon_150247 a rdfs:Class ;
  rdfs:label "Anoxybacillus" ;
  rdfs:subClassOf obo:NCBITaxon_1385 .

obo:NCBITaxon_726 a rdfs:Class ;
  rdfs:label "Haemophilus haemolyticus" ;
  rdfs:subClassOf obo:NCBITaxon_724 .

obo:OHMI_0000648 a rdfs:Class ;
  rdfs:label "expansion of Rothia in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Rothia up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000007 a rdfs:Class ;
  rdfs:label "viral microbiome"@en ;
  rdfs:comment "A microbiome that includes a collective population of virus" ;
  rdfs:subClassOf obo:OHMI_0000003 .

obo:OHMI_0000044 a rdfs:Class ;
  rdfs:label "expansion of B. fragilis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where B. fragilis is increased." ;
  rdfs:subClassOf obo:OHMI_0000333 .

obo:UBERON_0000014 a rdfs:Class ;
  rdfs:label "zone of skin" ;
  rdfs:comment "Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OHMI_0000355 a rdfs:Class ;
  rdfs:label "expansion of unclassified Proteobacteria in diarrheal patient gut"@en ;
  rdfs:comment "a diarrheal patient-gut microbiome interaction that shows an increase of unclassified Proteobacteria in patients in the gut of human diarrheal patient compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000067 .

obo:OHMI_0000450 a rdfs:Class ;
  rdfs:label "expansion of Acidovorax in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Acidovorax is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:OHMI_0000911 a rdfs:Class ;
  rdfs:label "depletion of Roseburia inulinivorans in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Roseburia inulinivorans down-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_286 a rdfs:Class ;
  rdfs:label "Pseudomonas" ;
  rdfs:subClassOf obo:NCBITaxon_72274 .

obo:OHMI_0000491 a rdfs:Class ;
  rdfs:label "COPD human gut microbiome interaction"@en ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:CHEBI_23367 a rdfs:Class ;
  rdfs:label "molecular entity" ;
  rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:DOID_3119 a rdfs:Class ;
  rdfs:label "gastrointestinal system cancer" ;
  rdfs:comment "An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system." ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_77 .

obo:OHMI_0000094 a rdfs:Class ;
  rdfs:label "expansion of Veillonella in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of Veillonella in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:OHMI_0000874 a rdfs:Class ;
  rdfs:label "depletion of Dorea in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Dorea down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_85030 a rdfs:Class ;
  rdfs:label "Geodermatophilaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1760 .

obo:NCBITaxon_712 a rdfs:Class ;
  rdfs:label "Pasteurellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OHMI_0000484 a rdfs:Class ;
  rdfs:label "microbiome-immune-cancer interaction"@en ;
  rdfs:comment "An interaction between microbiome and host immune system that is associated with cancer" ;
  rdfs:subClassOf obo:OHMI_0000011 , obo:OHMI_0000483 .

obo:OBI_1110122 a rdfs:Class ;
  rdfs:label "pathologic process"@en ;
  rdfs:comment "abnormal, harmful processes caused by or associated with a disease"@en ;
  rdfs:subClassOf obo:GO_0008150 .

obo:NCBITaxon_213849 a rdfs:Class ;
  rdfs:label "Campylobacterales" ;
  rdfs:subClassOf obo:NCBITaxon_29547 .

obo:OHMI_0000553 a rdfs:Class ;
  rdfs:label "expansion of Desulfobulbaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Desulfobulbaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_716546 a rdfs:Class ;
  rdfs:label "leotiomyceta" ;
  rdfs:subClassOf obo:NCBITaxon_716545 .

obo:OHMI_0000509 a rdfs:Class ;
  rdfs:label "expansion of Coriobacteriaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Coriobacteriaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000269 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacterium prausnitzii in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an decrease of Faecalibacterium prausnitzii in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000098 , obo:OHMI_0000255 .

obo:OHMI_0000525 a rdfs:Class ;
  rdfs:label "expansion of Erysipelotrichaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Erysipelotrichaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000542 a rdfs:Class ;
  rdfs:label "expansion of Leptotrichiaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Leptotrichiaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000531 a rdfs:Class ;
  rdfs:label "expansion of Selenomonas in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Selenomonas up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_816 a rdfs:Class ;
  rdfs:label "Bacteroides" ;
  rdfs:subClassOf obo:NCBITaxon_815 .

obo:OHMI_0000323 a rdfs:Class ;
  rdfs:label "depletion of R.albus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Ruminococcus albus is decreased." ;
  rdfs:subClassOf obo:OHMI_0000392 .

obo:NCBITaxon_2420509 a rdfs:Class ;
  rdfs:label "Gordonia insulae" ;
  rdfs:subClassOf obo:NCBITaxon_85007 .

obo:NCBITaxon_84112 a rdfs:Class ;
  rdfs:label "Eggerthella lenta" ;
  rdfs:subClassOf obo:NCBITaxon_84111 .

obo:OHMI_0000138 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides sp in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Bacteroides sp in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000116 .

obo:NCBITaxon_28111 a rdfs:Class ;
  rdfs:label "Bacteroides eggerthii" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:OHMI_0000282 a rdfs:Class ;
  rdfs:label "expansion of Salmonella in reactive arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with reactive arthritis that shows an expansion of Salmonella in rattus with reactive arthritis compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000280 .

obo:OHMI_0000519 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillales in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Lactobacillales up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000127 a rdfs:Class ;
  rdfs:label "depletion of Lachnospiraceae in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Lachnospiraceae  in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:OBI_0000073 a rdfs:Class ;
  rdfs:label "sample preparation for assay"@en ;
  rdfs:comment "A sample_preparation_for_assay is a protocol_application including material_enrollments and biomaterial_transformations. definition_source: OBI."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:CMO_0000000 a rdfs:Class ;
  rdfs:label "clinical measurement" ;
  rdfs:comment "A quantitative or qualitative value which is the result of an act of assessing a morphological or physiological state or property in a single individual or sample or a group of individuals or samples, based on direct observation or experimental manipulation." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OHMI_0000101 a rdfs:Class ;
  rdfs:label "expansion of Lachnospiraceae in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of Lachnospiraceae in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000099 .

obo:OHMI_0000473 a rdfs:Class ;
  rdfs:label "obsolete gamma diversity"@en ;
  rdfs:comment "the total species diversity in a landscape" .

obo:OHMI_0000360 a rdfs:Class ;
  rdfs:label "depletion of Bacteroidales in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroidales is decreased." ;
  rdfs:subClassOf obo:OHMI_0000357 .

obo:OHMI_0000827 a rdfs:Class ;
  rdfs:label "depletion of Ruminococcaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Ruminococcaceae down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_136 a rdfs:Class ;
  rdfs:label "Spirochaetales" ;
  rdfs:subClassOf obo:NCBITaxon_203692 .

obo:NCBITaxon_102148 a rdfs:Class ;
  rdfs:label "Solobacterium moorei" ;
  rdfs:subClassOf obo:NCBITaxon_123375 .

obo:OHMI_0000564 a rdfs:Class ;
  rdfs:label "expansion of Haemophilus hemolyticus in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Haemophilus hemolyticus up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000318 a rdfs:Class ;
  rdfs:label "depletion of P. oris in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Prevotella oris is decreased." ;
  rdfs:subClassOf obo:OHMI_0000336 .

obo:OHMI_0000052 a rdfs:Class ;
  rdfs:label "decreased organism quantity compared with fibromyalgia patients"@en ;
  rdfs:comment "A quality with a depleted quantity of a type of organism (e.g., bacteria inside human gut) compared with a patient control with the fibromyalgia (FM) disease." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:NCBITaxon_2591381 a rdfs:Class ;
  rdfs:label "Dysosmobacter" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:OHMI_0000500 a rdfs:Class ;
  rdfs:label "expansion of Proteobacteria in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Proteobacteria up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000853 a rdfs:Class ;
  rdfs:label "expansion of Rikenellaceae in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Rikenellaceae up-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:OHMI_0000098 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacterium in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Faecalibacterium  in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:NCBITaxon_210 a rdfs:Class ;
  rdfs:label "Helicobacter pylori" ;
  rdfs:subClassOf obo:NCBITaxon_209 .

obo:OHMI_0000033 a rdfs:Class ;
  rdfs:label "descreased microbiome organism diversity"@en ;
  rdfs:comment "A quality with an decreased microbiome organism dirversity in a host microbiome environment (e.g., gut)." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OHMI_0000112 a rdfs:Class ;
  rdfs:label "depletion of Firmicutes in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an decrease of Firmicutes in patients with SLEcompared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000053 .

obo:OHMI_0000612 a rdfs:Class ;
  rdfs:label "expansion of Acinetobacter in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Acinetobacter up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:NCBITaxon_165696 a rdfs:Class ;
  rdfs:label "Novosphingobium" ;
  rdfs:subClassOf obo:NCBITaxon_41297 .

obo:OHMI_0000651 a rdfs:Class ;
  rdfs:label "depletion of Firmicutes in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Firmicutes down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000607 a rdfs:Class ;
  rdfs:label "depletion of Megasphaera in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Megasphaera down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_909656 a rdfs:Class ;
  rdfs:label "Phocaeicola" ;
  rdfs:subClassOf obo:NCBITaxon_815 .

obo:OHMI_0000885 a rdfs:Class ;
  rdfs:label "expansion of Barnesiella intestinihominis in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Barnesiella intestinihominis up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000691 a rdfs:Class ;
  rdfs:label "expansion of Rhodococcus pyridinivorans in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Rhodococcus pyridinivorans up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000580 a rdfs:Class ;
  rdfs:label "depletion of Prevotellaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Prevotellaceae down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000662 a rdfs:Class ;
  rdfs:label "depletion of Neisseria in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Neisseria down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000916 a rdfs:Class ;
  rdfs:label "depletion of Firmicutes in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Firmicutes down-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000461 a rdfs:Class ;
  rdfs:label "dysbiosis"@en ;
  rdfs:comment "An abnormal phenotype that has a microbial imbalance or maladaption on or inside the body." ;
  rdfs:subClassOf obo:UPHENO_0001002 .

obo:IAO_0000104 a rdfs:Class ;
  rdfs:label "plan specification"@en ;
  rdfs:comment "A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:NCBITaxon_577310 a rdfs:Class ;
  rdfs:label "Parasutterella" ;
  rdfs:subClassOf obo:NCBITaxon_995019 .

obo:OHMI_0000692 a rdfs:Class ;
  rdfs:label "expansion of Phocaeicola massiliensis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Phocaeicola massiliensis up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_40520 a rdfs:Class ;
  rdfs:label "Blautia obeum" ;
  rdfs:subClassOf obo:NCBITaxon_572511 .

obo:NCBITaxon_135622 a rdfs:Class ;
  rdfs:label "Alteromonadales" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OBI_0600024 a rdfs:Class ;
  rdfs:label "maintaining cell culture"@en ;
  rdfs:comment "a protocol application in which cells are kept alive in a defined environment outside of an organism.  part of cell_culturing"@en ;
  rdfs:subClassOf obo:OBI_0000838 .

obo:OHMI_0000388 a rdfs:Class ;
  rdfs:label "expansion of E. coli NC101 in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Escherichia coli NC101 is increased." ;
  rdfs:subClassOf obo:OHMI_0000395 .

obo:OHMI_0000791 a rdfs:Class ;
  rdfs:label "depletion of Megamonas funiformis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Megamonas funiformis down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000239 a rdfs:Class ;
  rdfs:label "depletion of Haemophilus parainfluenzae in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity  microbiome interaction that shows a  depletion of Haemophilus parainfluenzae in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:NCBITaxon_1661 a rdfs:Class ;
  rdfs:label "Trueperella pyogenes" ;
  rdfs:subClassOf obo:NCBITaxon_2049 .

obo:OHMI_0000751 a rdfs:Class ;
  rdfs:label "expansion of Bulleidia in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bulleidia up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_574697 a rdfs:Class ;
  rdfs:label "Butyricimonas" ;
  rdfs:subClassOf obo:NCBITaxon_1853231 .

obo:OHMI_0000843 a rdfs:Class ;
  rdfs:label "expansion of Odoribacter in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Odoribacter up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:UBERON_0001007 a rdfs:Class ;
  rdfs:label "digestive system" ;
  rdfs:comment "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:HP_0001513 a rdfs:Class ;
  rdfs:label "Obesity" ;
  rdfs:comment "Accumulation of substantial excess body fat." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:OHMI_0000018 a rdfs:Class ;
  rdfs:label "microbiome in human urogenital system"@en ;
  rdfs:comment "a human microbiome that is located in a human urogenital system" ;
  rdfs:subClassOf obo:OHMI_0000002 .

obo:OHMI_0000780 a rdfs:Class ;
  rdfs:label "depletion of Amycolatopsis sp. in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Amycolatopsis sp. down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000376 a rdfs:Class ;
  rdfs:label "expansion of Coriobacteriaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Coriobacteriaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000080 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in RA human respiratory airway"@en ;
  rdfs:comment "RA human respiratory airway microbiome interaction that shows an decrease of Prevotella in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000078 .

obo:NCBITaxon_216572 a rdfs:Class ;
  rdfs:label "Oscillospiraceae" ;
  rdfs:subClassOf obo:NCBITaxon_186802 .

obo:OHMI_0000150 a rdfs:Class ;
  rdfs:label "depletion of Alistipes in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Alistipes in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:NCBITaxon_1016 a rdfs:Class ;
  rdfs:label "Capnocytophaga" ;
  rdfs:subClassOf obo:NCBITaxon_49546 .

obo:OHMI_0000739 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroides up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000494 a rdfs:Class ;
  rdfs:label "COPD human oral microbiome interaction"@en ;
  rdfs:comment "A human oral cavity microbiome interaction where he human is diseased with Chronic obstructive pulmonary disease (COPD)" ;
  rdfs:subClassOf obo:OHMI_0000036 .

obo:NCBITaxon_5475 a rdfs:Class ;
  rdfs:label "Candida" ;
  rdfs:subClassOf obo:NCBITaxon_766764 .

obo:BFO_0000002 a rdfs:Class ;
  rdfs:label "continuant"@en ;
  rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:NCBITaxon_2048137 a rdfs:Class ;
  rdfs:label "Agathobaculum" ;
  rdfs:subClassOf obo:NCBITaxon_3085642 .

obo:OHMI_0000109 a rdfs:Class ;
  rdfs:label "expansion of Tannerella forsythia in AS human oral cavity"@en ;
  rdfs:comment "an AS human oral cavity  microbiome interaction that shows an expansion of rare taxa,Tannerella forsythia in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000106 .

obo:OHMI_0000386 a rdfs:Class ;
  rdfs:label "expansion of A. putredinis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Alistipes putredinis is increased." ;
  rdfs:subClassOf obo:OHMI_0000341 .

obo:OHMI_0000811 a rdfs:Class ;
  rdfs:label "depletion of Thauera in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Thauera down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_437897 a rdfs:Class ;
  rdfs:label "Megamonas funiformis" ;
  rdfs:subClassOf obo:NCBITaxon_158846 .

obo:OHMI_0000329 a rdfs:Class ;
  rdfs:label "expansion of C.farmeri in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Citrobacter farmeri is increased." ;
  rdfs:subClassOf obo:OHMI_0000349 .

obo:OHMI_0000664 a rdfs:Class ;
  rdfs:label "patient"@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:OHMI_0000162 a rdfs:Class ;
  rdfs:label "depletion of Proteobacteria in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an decrease of Proteobacteria in patients with  PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000122 .

obo:OHMI_0000844 a rdfs:Class ;
  rdfs:label "expansion of Parabacteroides in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Parabacteroides up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000103 a rdfs:Class ;
  rdfs:label "expansion of Prevotellaceae in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of Prevotellaceae in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000099 .

obo:OHMI_0000562 a rdfs:Class ;
  rdfs:label "expansion of Hallella in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Hallella up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_44259 a rdfs:Class ;
  rdfs:label "Filifactor" ;
  rdfs:subClassOf obo:NCBITaxon_3082720 .

obo:NCBITaxon_305911 a rdfs:Class ;
  rdfs:label "Clostridium sp. cp01.19" ;
  rdfs:subClassOf obo:NCBITaxon_2614128 .

obo:OBI_0000011 a rdfs:Class ;
  rdfs:label "planned process"@en ;
  rdfs:comment "A processual entity that realizes a plan which is the concretization of a plan specification."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0001931 a rdfs:Class ;
  rdfs:label "scalar value specification" ;
  rdfs:comment "A value specification that consists of two parts: a numeral and a unit label" ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:NCBITaxon_1582 a rdfs:Class ;
  rdfs:label "Lacticaseibacillus casei" ;
  rdfs:subClassOf obo:NCBITaxon_2759736 .

obo:NCBITaxon_84162 a rdfs:Class ;
  rdfs:label "Cryptobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_1643826 .

obo:NCBITaxon_1164882 a rdfs:Class ;
  rdfs:label "Lachnoanaerobaculum" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_39486 a rdfs:Class ;
  rdfs:label "Dorea formicigenerans" ;
  rdfs:subClassOf obo:NCBITaxon_189330 .

obo:OHMI_0000586 a rdfs:Class ;
  rdfs:label "expansion of Sphingomonas in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Sphingomonas up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:IAO_0000033 a rdfs:Class ;
  rdfs:label "directive information entity"@en ;
  rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OHMI_0000590 a rdfs:Class ;
  rdfs:label "expansion of Moraxella in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Moraxella up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_84998 a rdfs:Class ;
  rdfs:label "Coriobacteriia" ;
  rdfs:subClassOf obo:NCBITaxon_201174 .

obo:NCBITaxon_53460 a rdfs:Class ;
  rdfs:label "Nakamurella" ;
  rdfs:subClassOf obo:NCBITaxon_85031 .

obo:NCBITaxon_538 a rdfs:Class ;
  rdfs:label "Eikenella" ;
  rdfs:subClassOf obo:NCBITaxon_481 .

obo:NCBITaxon_1219642 a rdfs:Class ;
  rdfs:label "Solobacterium sp. S4-A19" ;
  rdfs:subClassOf obo:NCBITaxon_123375 .

obo:OBI_0000953 a rdfs:Class ;
  rdfs:label "processed specimen" ;
  rdfs:comment "A specimen that has been intentionally physically modified." ;
  rdfs:subClassOf obo:OBI_0000047 , obo:OBI_0100051 .

obo:OHMI_0000183 a rdfs:Class ;
  rdfs:label "arthritis rat-gut microbiome interaction" ;
  rdfs:comment "A rattus gut-microbiome interaction that is associated with arthritis." ;
  rdfs:subClassOf obo:OHMI_0000095 .

obo:OHMI_0000433 a rdfs:Class ;
  rdfs:label "expansion of A. actinomycetemcomitans in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Aggregatibacter actinomycetemcomitans is increased." ;
  rdfs:subClassOf obo:OHMI_0000371 .

obo:DOID_5517 a rdfs:Class ;
  rdfs:label "stomach carcinoma" ;
  rdfs:comment "A stomach cancer that is located_in the stomach." ;
  rdfs:subClassOf obo:DOID_10534 , obo:DOID_305 .

obo:NCBITaxon_1150298 a rdfs:Class ;
  rdfs:label "Fusicatenibacter saccharivorans" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_976 a rdfs:Class ;
  rdfs:label "Bacteroidota" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 , obo:OHMI_0000671 .

obo:OHMI_0000611 a rdfs:Class ;
  rdfs:label "expansion of Prevotella in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Prevotella up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000888 a rdfs:Class ;
  rdfs:label "expansion of Anaerotruncus in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Anaerotruncus up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000334 a rdfs:Class ;
  rdfs:label "expansion of Odoribacter in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Odoribacter is increased." ;
  rdfs:subClassOf obo:OHMI_0000305 .

obo:OHMI_0000546 a rdfs:Class ;
  rdfs:label "expansion of Balneimonas (Microvirga） in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Balneimonas (Microvirga） up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000088 a rdfs:Class ;
  rdfs:label "depletion of Kingella in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of Kingella in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:OHMI_0000572 a rdfs:Class ;
  rdfs:label "depletion of Geodermatophilaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Geodermatophilaceae down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000133 a rdfs:Class ;
  rdfs:label "expansion of Parasporobacterium in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Parasporobacterium in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:NCBITaxon_77020 a rdfs:Class ;
  rdfs:label "Malassezia pachydermatis" ;
  rdfs:subClassOf obo:NCBITaxon_55193 .

obo:OHMI_0000733 a rdfs:Class ;
  rdfs:label "expansion of Rothia in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Rothia up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000172 a rdfs:Class ;
  rdfs:label "depletion of Lactobacillus in SLE  mouse gut"@en ;
  rdfs:comment "An association of musculus gut microbiota with system lupus erythematosus(SLE) that shows a depletion of Lactobacillus in musculus with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000197 .

obo:NCBITaxon_657 a rdfs:Class ;
  rdfs:label "Photobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_641 .

obo:OHMI_0000345 a rdfs:Class ;
  rdfs:label "RA human-urine microbiome interaction"@en ;
  rdfs:comment "A human urine-microbiome interaction that is associated with rheumatoid arthritis (RA)." ;
  rdfs:subClassOf obo:OHMI_0000344 .

obo:NCBITaxon_33882 a rdfs:Class ;
  rdfs:label "Microbacterium" ;
  rdfs:subClassOf obo:NCBITaxon_85023 .

obo:OHMI_0000551 a rdfs:Class ;
  rdfs:label "expansion of Serratia in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Serratia up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_872 a rdfs:Class ;
  rdfs:label "Desulfovibrio" ;
  rdfs:subClassOf obo:NCBITaxon_194924 .

obo:NCBITaxon_157 a rdfs:Class ;
  rdfs:label "Treponema" ;
  rdfs:subClassOf obo:NCBITaxon_136 .

obo:UBERON_0000061 a rdfs:Class ;
  rdfs:label "anatomical structure" ;
  rdfs:comment "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:DOID_409 a rdfs:Class ;
  rdfs:label "liver disease" ;
  rdfs:subClassOf obo:DOID_28 , obo:DOID_3118 .

obo:OHMI_0000833 a rdfs:Class ;
  rdfs:label "depletion of Planctomycetes in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Planctomycetes down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_480 a rdfs:Class ;
  rdfs:label "Moraxella catarrhalis" ;
  rdfs:subClassOf obo:NCBITaxon_475 .

obo:OHMI_0000352 a rdfs:Class ;
  rdfs:label "'depletion of Bacteroides in colorectal cancer human gut'"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroides is decreased." ;
  rdfs:subClassOf obo:OHMI_0000360 .

obo:OHMI_0000901 a rdfs:Class ;
  rdfs:label "expansion of Corynebacteriaceae in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Corynebacteriaceae up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_29523 a rdfs:Class ;
  rdfs:label "Bacteroides sp." ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:OHMI_0000401 a rdfs:Class ;
  rdfs:label "expansion of Salmonella in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Salmonella is increased." ;
  rdfs:subClassOf obo:OHMI_0000349 .

obo:NCBITaxon_171549 a rdfs:Class ;
  rdfs:label "Bacteroidales" ;
  rdfs:subClassOf obo:NCBITaxon_200643 .

obo:OHMI_0000085 a rdfs:Class ;
  rdfs:label "expansion of Actinobacteria<phylum> in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Actinobacteria<phylum> in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000744 a rdfs:Class ;
  rdfs:label "expansion of Gemella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Gemella up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000807 a rdfs:Class ;
  rdfs:label "depletion of Bacteroidetes helcogenes in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroidetes helcogenes down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000144 a rdfs:Class ;
  rdfs:label "depletion of Oscillibacter in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Oscillibacter in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000128 .

obo:NCBITaxon_7227 a rdfs:Class ;
  rdfs:label "Drosophila melanogaster" ;
  rdfs:subClassOf obo:NCBITaxon_197562 .

obo:OHMI_0000228 a rdfs:Class ;
  rdfs:label "expansion of Eubacterium in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an expansion of Eubacterium in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000053 .

obo:OHMI_0000622 a rdfs:Class ;
  rdfs:label "expansion of Aeromonadales in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Aeromonadales up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:CMO_0002104 a rdfs:Class ;
  rdfs:label "serum immunoglobulin M level" ;
  rdfs:comment "The amount in a specified sample of serum of one or more types of immunoglobulin M (IgM), one of the five classes of antibodies produced by the body. IgM is found in circulating body fluids and is the first class of antibodies to appear in response to an initial exposure to an antigen." ;
  rdfs:subClassOf obo:CMO_0001276 .

obo:DOID_0060032 a rdfs:Class ;
  rdfs:label "autoimmune disease of musculoskeletal system" ;
  rdfs:comment "An autoimmune hypersensitivity disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the musculoskeletal system." ;
  rdfs:subClassOf obo:DOID_17 , obo:DOID_417 .

obo:OHMI_0000535 a rdfs:Class ;
  rdfs:label "expansion of Oribacterium in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Oribacterium up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_853 a rdfs:Class ;
  rdfs:label "Faecalibacterium prausnitzii" ;
  rdfs:subClassOf obo:NCBITaxon_216851 .

obo:OHMI_0000139 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides xylanisolvens XB1A in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Bacteroides xylanisolvens XB1A in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000116 .

obo:OHMI_0000032 a rdfs:Class ;
  rdfs:label "increased organism quantity compared with healthy control"@en ;
  rdfs:comment "A quality with an increased quantity of a type of organism (e.g., bacteria inside human gut) compared with control." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:NCBITaxon_12721 a rdfs:Class ;
  rdfs:label "Human immunodeficiency virus" ;
  rdfs:subClassOf obo:NCBITaxon_2732514 .

obo:NCBITaxon_451864 a rdfs:Class ;
  rdfs:label "Dikarya" ;
  rdfs:subClassOf obo:NCBITaxon_4751 .

obo:NCBITaxon_35832 a rdfs:Class ;
  rdfs:label "Bilophila" ;
  rdfs:subClassOf obo:NCBITaxon_194924 .

obo:NCBITaxon_118747 a rdfs:Class ;
  rdfs:label "Bulleidia" ;
  rdfs:subClassOf obo:NCBITaxon_128827 .

obo:NCBITaxon_735 a rdfs:Class ;
  rdfs:label "Haemophilus parahaemolyticus" ;
  rdfs:subClassOf obo:NCBITaxon_724 .

obo:NCBITaxon_1816678 a rdfs:Class ;
  rdfs:label "Christensenella timonensis" ;
  rdfs:subClassOf obo:NCBITaxon_990719 .

obo:OHMI_0000721 a rdfs:Class ;
  rdfs:label "expansion of Klebsiella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Klebsiella up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000161 a rdfs:Class ;
  rdfs:label "depletion of Actinobacteria <phylum> in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an decrease of Actinobacteria <phylum> in patients with  PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000122 .

obo:NCBITaxon_418240 a rdfs:Class ;
  rdfs:label "Blautia wexlerae" ;
  rdfs:subClassOf obo:NCBITaxon_572511 .

obo:OHMI_0000353 a rdfs:Class ;
  rdfs:label "depletion of Clostridiales in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Clostridiales is decreased." ;
  rdfs:subClassOf obo:OHMI_0000356 .

obo:OHMI_0000822 a rdfs:Class ;
  rdfs:label "depletion of Butyricicoccus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Butyricicoccus down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_283 a rdfs:Class ;
  rdfs:label "Comamonas" ;
  rdfs:subClassOf obo:NCBITaxon_80864 .

obo:NCBITaxon_292628 a rdfs:Class ;
  rdfs:label "Anaerolineaceae"@en ;
  rdfs:subClassOf obo:NCBITaxon_292629 .

obo:NCBITaxon_47678 a rdfs:Class ;
  rdfs:label "Bacteroides caccae" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:NCBITaxon_1351 a rdfs:Class ;
  rdfs:label "Enterococcus faecalis" ;
  rdfs:subClassOf obo:NCBITaxon_1350 .

obo:PCO_0000075 a rdfs:Class ;
  rdfs:label "beta diversity"@en ;
  rdfs:comment "A community species diversity that is the ratio between regional and local species diversity." ;
  rdfs:subClassOf obo:PCO_0000019 .

obo:OHMI_0000575 a rdfs:Class ;
  rdfs:label "depletion of Humicoccus in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Humicoccus down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000616 a rdfs:Class ;
  rdfs:label "expansion of Pontibacillus in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Pontibacillus up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:NCBITaxon_76857 a rdfs:Class ;
  rdfs:label "Fusobacterium polymorphum" ;
  rdfs:subClassOf obo:NCBITaxon_848 .

obo:OHMI_0000475 a rdfs:Class ;
  rdfs:label "host microbiome restoration by treatment"@en ;
  rdfs:comment "A host microbiome restoration that is due to a treatment" ;
  rdfs:subClassOf obo:OHMI_0000474 .

obo:HP_0002028 a rdfs:Class ;
  rdfs:label "Chronic diarrhea" ;
  rdfs:comment "The presence of chronic diarrhea, which is usually taken to mean diarrhea that has persisted for over 4 weeks." ;
  rdfs:subClassOf obo:HP_0002014 .

obo:NCBITaxon_657309 a rdfs:Class ;
  rdfs:label "Bacteroides xylanisolvens XB1A" ;
  rdfs:subClassOf obo:NCBITaxon_371601 .

obo:CL_0000578 a rdfs:Class ;
  rdfs:label "experimentally modified cell in vitro" ;
  rdfs:comment "A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure." ;
  rdfs:subClassOf obo:CL_0000000 , obo:OBI_0000047 .

obo:OHMI_0000840 a rdfs:Class ;
  rdfs:label "expansion of Akkermansia in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Akkermansia up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000206 a rdfs:Class ;
  rdfs:label "Bacteroides depletion in arthritis mouse gut"@en ;
  rdfs:comment "An association of musculus gut microbiota with arthritis  that shows a depleted quantity of Bacteroides in musculus with arthritis compared with healty controls." ;
  rdfs:subClassOf obo:OHMI_0000203 .

obo:OHMI_0000241 a rdfs:Class ;
  rdfs:label "expansion of Fretibacterium fastidiosum in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity  microbiome interaction that shows an expansion of Fretibacterium fastidiosum in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:NCBITaxon_3702 a rdfs:Class ;
  rdfs:label "Arabidopsis thaliana" ;
  rdfs:subClassOf obo:NCBITaxon_71275 .

obo:NCBITaxon_906 a rdfs:Class ;
  rdfs:label "Megasphaera" ;
  rdfs:subClassOf obo:NCBITaxon_31977 .

obo:OHMI_0000468 a rdfs:Class ;
  rdfs:label "relative species abundance"@en ;
  rdfs:comment "A quality of ecological community that refers to how common or rare a species is relative to other species in a defined location or community" ;
  rdfs:subClassOf obo:PCO_0000004 .

obo:OHMI_0000877 a rdfs:Class ;
  rdfs:label "depletion of Erysipelotrichaceae in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Erysipelotrichaceae down-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_1903411 a rdfs:Class ;
  rdfs:label "Yersiniaceae" ;
  rdfs:subClassOf obo:NCBITaxon_91347 .

obo:OHMI_0000890 a rdfs:Class ;
  rdfs:label "expansion of Barnesiella in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Barnesiella up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000608 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Prevotella down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000166 a rdfs:Class ;
  rdfs:label "PsA human oral cavity microbiome interaction"@en ;
  rdfs:comment "A human oral cavity microbiome interaction that is associated with  psoriatic arthritis (PsA)." ;
  rdfs:subClassOf obo:OHMI_0000036 .

obo:UBERON_0000160 a rdfs:Class ;
  rdfs:label "intestine" ;
  rdfs:comment "Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine." ;
  rdfs:subClassOf obo:UBERON_0004921 .

obo:NCBITaxon_194924 a rdfs:Class ;
  rdfs:label "Desulfovibrionaceae" ;
  rdfs:subClassOf obo:NCBITaxon_200940 .

obo:OBI_0000441 a rdfs:Class ;
  rdfs:label "assay objective"@en ;
  rdfs:comment "an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)"@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:NCBITaxon_810 a rdfs:Class ;
  rdfs:label "Chlamydia" ;
  rdfs:subClassOf obo:NCBITaxon_1783257 .

obo:UBERON_0002048 a rdfs:Class ;
  rdfs:label "lung" ;
  rdfs:comment "Respiration organ that develops as an outpocketing of the esophagus." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/issues/701> ;
  rdfs:subClassOf obo:UBERON_0000062 .

obo:NCBITaxon_2005525 a rdfs:Class ;
  rdfs:label "Tannerellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_171549 .

obo:NCBITaxon_1598 a rdfs:Class ;
  rdfs:label "Limosilactobacillus reuteri" ;
  rdfs:subClassOf obo:NCBITaxon_2742598 .

obo:OHMI_0000114 a rdfs:Class ;
  rdfs:label "gout human-gut microbiome interaction"@en ;
  rdfs:comment "A human gut-microbiome interaction that is associated with gout." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:OHMI_0000217 a rdfs:Class ;
  rdfs:label "depletion of Actynomyces in RA human respiratory airway"@en ;
  rdfs:comment "RA human respiratory airway microbiome interaction that shows an decrease of Actynomyces in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000078 .

obo:OHMI_0000010 a rdfs:Class ;
  rdfs:label "fungal microbiome of lung"@en ;
  rdfs:comment "A fungal microbiome that is located in a lung of a host organism" ;
  rdfs:subClassOf obo:OHMI_0000006 .

obo:OHMI_0000321 a rdfs:Class ;
  rdfs:label "depletion of L.pectinoschiza in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Lachnospira pectinoschiza is decreased." ;
  rdfs:subClassOf obo:OHMI_0000346 .

obo:OHMI_0000021 a rdfs:Class ;
  rdfs:label "human-gut microbiome interaction"@en ;
  rdfs:comment "An interaction between human and gut microbiome." ;
  rdfs:subClassOf obo:OHMI_0000019 .

obo:NCBITaxon_1763 a rdfs:Class ;
  rdfs:label "Mycobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_85007 .

obo:NCBITaxon_106588 a rdfs:Class ;
  rdfs:label "Pseudoflavonifractor capillosus" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:OHMI_0000068 a rdfs:Class ;
  rdfs:label "expansion of Klebsiella in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an expansion of Klebsiella in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000053 .

obo:PR_000000001 a rdfs:Class ;
  rdfs:label "protein" ;
  rdfs:comment "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA." ;
  rdfs:subClassOf obo:CHEBI_16670 .

obo:OHMI_0000187 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillus fermentum in arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Lactobacillus fermentum in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:NCBITaxon_1263 a rdfs:Class ;
  rdfs:label "Ruminococcus" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:NCBITaxon_1261 a rdfs:Class ;
  rdfs:label "Peptostreptococcus anaerobius" ;
  rdfs:subClassOf obo:NCBITaxon_1257 .

obo:NCBITaxon_448465 a rdfs:Class ;
  rdfs:label "Eleutherodactylus lentus" ;
  rdfs:subClassOf obo:NCBITaxon_8342 .

obo:OHMI_0000299 a rdfs:Class ;
  rdfs:label "expansion of Slackia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Slackia is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_28117 a rdfs:Class ;
  rdfs:label "Alistipes putredinis" ;
  rdfs:subClassOf obo:NCBITaxon_239759 .

obo:NCBITaxon_292625 a rdfs:Class ;
  rdfs:label "Anaerolineae"@en ;
  rdfs:subClassOf obo:NCBITaxon_200795 .

obo:OGMS_0000031 a rdfs:Class ;
  rdfs:label "disease" ;
  rdfs:comment "A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:OHMI_0000698 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium longum in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium longum up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OBI_0000671 a rdfs:Class ;
  rdfs:label "sample from organism" ;
  rdfs:comment "a material obtained from an organism in order to be a representative of the whole" ;
  rdfs:subClassOf obo:OBI_0000747 , obo:OBI_0001479 .

obo:OHMI_0000151 a rdfs:Class ;
  rdfs:label "depletion of Propionibacterium acnes 17B in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an decrease of Propionibacterium acnes 17B in patients with  PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000161 .

obo:OHMI_0000658 a rdfs:Class ;
  rdfs:label "depletion of Clostridium in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Clostridium down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000077 a rdfs:Class ;
  rdfs:label "human respiratory airway microbiome interaction"@en ;
  rdfs:comment "An interaction between human and respiratory airway microbiome." ;
  rdfs:subClassOf obo:OHMI_0000019 .

obo:OHMI_0000919 a rdfs:Class ;
  rdfs:label "expansion of Parasutterella in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Parasutterella up-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000370 a rdfs:Class ;
  rdfs:label "expansion of Veillonellaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Veillonellaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000230 a rdfs:Class ;
  rdfs:label "expansion of Rhodococcus in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an expansion of Rhodococcus in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000053 .

obo:OHMI_0000248 a rdfs:Class ;
  rdfs:label "expansion of Anaerolineaceae in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Anaerolineaceae in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000247 .

obo:OHMI_0000869 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacterium in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Faecalibacterium down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000680 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides thetaiotaomicron in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroides thetaiotaomicron up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_67824 a rdfs:Class ;
  rdfs:label "Citrobacter farmeri" ;
  rdfs:subClassOf obo:NCBITaxon_544 .

obo:NCBITaxon_55193 a rdfs:Class ;
  rdfs:label "Malassezia" ;
  rdfs:subClassOf obo:NCBITaxon_5204 , obo:OHMI_0000460 .

obo:DOID_684 a rdfs:Class ;
  rdfs:label "hepatocellular carcinoma" ;
  rdfs:comment "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes." ;
  rdfs:subClassOf obo:DOID_686 .

obo:OHMI_0000591 a rdfs:Class ;
  rdfs:label "expansion of Haemophilus influenzae in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Haemophilus influenzae up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:DOID_0050589 a rdfs:Class ;
  rdfs:label "inflammatory bowel disease" ;
  rdfs:comment "An intestinal disease characterized by inflammation located_in all parts of digestive tract." ;
  rdfs:subClassOf obo:DOID_5295 .

obo:NCBITaxon_397864 a rdfs:Class ;
  rdfs:label "Barnesiella" ;
  rdfs:subClassOf obo:NCBITaxon_2005519 .

obo:NCBITaxon_265975 a rdfs:Class ;
  rdfs:label "Oribacterium" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000251 a rdfs:Class ;
  rdfs:label "expansion of Rhodococcus in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Rhodococcus in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000250 .

obo:OHMI_0000310 a rdfs:Class ;
  rdfs:label "depletion of Salmonella enterica subsp. enterica in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Salmonella enterica subsp. enterica is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:CHEBI_16670 a rdfs:Class ;
  rdfs:label "peptide" ;
  rdfs:comment "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ;
  rdfs:subClassOf obo:CHEBI_33839 .

obo:OHMI_0000381 a rdfs:Class ;
  rdfs:label "depletion of F. prausnitzii in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Faecalibacterium prausnitzii is decreased." ;
  rdfs:subClassOf obo:OHMI_0000378 .

obo:NCBITaxon_35783 a rdfs:Class ;
  rdfs:label "Enterococcus sp." ;
  rdfs:subClassOf obo:NCBITaxon_1350 .

obo:NCBITaxon_837 a rdfs:Class ;
  rdfs:label "Porphyromonas gingivalis" ;
  rdfs:subClassOf obo:NCBITaxon_836 .

obo:NCBITaxon_235572 a rdfs:Class ;
  rdfs:label "Candidatus Portiera" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OHMI_0000419 a rdfs:Class ;
  rdfs:label "expansion of F. hwasookii in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacterium hwasookii is increased." ;
  rdfs:subClassOf obo:OHMI_0000289 .

obo:DOID_3342 a rdfs:Class ;
  rdfs:label "bone inflammation disease" ;
  rdfs:comment "A bone disease that results_in inflammation of the located_in bone." ;
  rdfs:subClassOf obo:DOID_65 .

obo:BFO_0000019 a rdfs:Class ;
  rdfs:label "quality"@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:OHMI_0000140 a rdfs:Class ;
  rdfs:label "expansion of Holdemania in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Holdemania in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:NCBITaxon_103816 a rdfs:Class ;
  rdfs:label "Rhodococcus pyridinivorans" ;
  rdfs:subClassOf obo:NCBITaxon_1827 .

obo:PATO_0001236 a rdfs:Class ;
  rdfs:label "process quality" ;
  rdfs:comment "A quality which inheres in an process." ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:NCBITaxon_258514 a rdfs:Class ;
  rdfs:label "Acetanaerobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:NCBITaxon_579 a rdfs:Class ;
  rdfs:label "Kluyvera" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:NCBITaxon_4751 a rdfs:Class ;
  rdfs:label "Fungi" ;
  rdfs:subClassOf obo:NCBITaxon_33154 .

obo:NCBITaxon_158846 a rdfs:Class ;
  rdfs:label "Megamonas" ;
  rdfs:subClassOf obo:NCBITaxon_1843491 .

obo:OBI_0001619 a rdfs:Class ;
  rdfs:label "specimen collection time measurement datum"@en ;
  rdfs:comment "A time measurement datum that is the measure of the time when the specimens are collected."@en ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OHMI_0000262 a rdfs:Class ;
  rdfs:label "expansion of Prevotella in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Prevotella in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000038 , obo:OHMI_0000051 , obo:OHMI_0000255 .

obo:NCBITaxon_484 a rdfs:Class ;
  rdfs:label "Neisseria flavescens" ;
  rdfs:subClassOf obo:NCBITaxon_482 .

obo:PCO_0000078 a rdfs:Class ;
  rdfs:label "seedling density"@en ;
  rdfs:comment "The density of seedlings in an ecological community or population, often measured as the number of seedlings per area." ;
  rdfs:subClassOf obo:PCO_0000077 .

obo:PATO_0000011 a rdfs:Class ;
  rdfs:label "age" ;
  rdfs:comment "A time quality inhering in a bearer by virtue of how long the bearer has existed." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:OHMI_0000237 a rdfs:Class ;
  rdfs:label "depletion of Capnocytophaga gingivalis in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity microbiome interaction that shows an decrease of Capnocytophaga gingivalis  in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:OHMI_0000760 a rdfs:Class ;
  rdfs:label "expansion of Thomasclavelia in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Thomasclavelia up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_172900 a rdfs:Class ;
  rdfs:label "Victivallis" ;
  rdfs:subClassOf obo:NCBITaxon_256845 .

obo:NCBITaxon_1380 a rdfs:Class ;
  rdfs:label "Atopobium" ;
  rdfs:subClassOf obo:NCBITaxon_1643824 .

obo:OHMI_0000337 a rdfs:Class ;
  rdfs:label "depletion of Porphyromonadaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Porphyromonadaceae is decreased." ;
  rdfs:subClassOf obo:OHMI_0000360 .

obo:NCBITaxon_821 a rdfs:Class ;
  rdfs:label "Phocaeicola vulgatus" ;
  rdfs:subClassOf obo:NCBITaxon_909656 .

obo:OHMI_0000867 a rdfs:Class ;
  rdfs:label "depletion of Victivallis in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Victivallis down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_1182749 a rdfs:Class ;
  rdfs:label "Cutibacterium acnes 17B" ;
  rdfs:subClassOf obo:NCBITaxon_31957 .

obo:OHMI_0000627 a rdfs:Class ;
  rdfs:label "depletion of Moraxellaceae in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Moraxellaceae down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000710 a rdfs:Class ;
  rdfs:label "expansion of Selenomonas ruminantium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Selenomonas ruminantium up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000858 a rdfs:Class ;
  rdfs:label "expansion of Pseudomonadota in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Pseudomonadota up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000507 a rdfs:Class ;
  rdfs:label "expansion of Neisseriaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Neisseriaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000125 a rdfs:Class ;
  rdfs:label "depletion of Vibrio in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Vibrio  in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000123 .

obo:CMO_0001276 a rdfs:Class ;
  rdfs:label "serum immunoglobulin measurement" ;
  rdfs:comment "Any measurement related to immunoglobulin, any of several classes of proteins produced by plasma cells and lymphocytes which play essential roles in the immune system, for example, attaching to foreign substances in an effort to destroy them, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." ;
  rdfs:subClassOf obo:CMO_0001531 .

obo:OHMI_0000776 a rdfs:Class ;
  rdfs:label "expansion of Spirochaetota in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Spirochaetota up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000176 a rdfs:Class ;
  rdfs:label "expansion of Prevotella in AS  rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with ankylosing spondylitis(AS) that shows an expansion of Prevotella in rattus with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000110 .

obo:OHMI_0000408 a rdfs:Class ;
  rdfs:label "expansion of P. mirabilis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Proteus mirabilis is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:NCBITaxon_1314 a rdfs:Class ;
  rdfs:label "Streptococcus pyogenes" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:OHMI_0000057 a rdfs:Class ;
  rdfs:label "expansion of Fusobacterium sp. in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacterium sp. is increased." ;
  rdfs:subClassOf obo:OHMI_0000289 .

obo:OHMI_0000090 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in diarrheal patient gut"@en ;
  rdfs:comment "a diarrheal patient-gut microbiome interaction that shows an decrease of Prevotella in patients in the gut of human diarrheal patient compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000067 .

obo:OHMI_0000567 a rdfs:Class ;
  rdfs:label "expansion of Burkholderia in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Burkholderia up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_328812 a rdfs:Class ;
  rdfs:label "Parabacteroides goldsteinii" ;
  rdfs:subClassOf obo:NCBITaxon_375288 .

obo:OHMI_0000457 a rdfs:Class ;
  rdfs:label "expansion of F. nucleatum subsp. animalis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacterium nucleatum subsp. animalis is increased." ;
  rdfs:subClassOf obo:OHMI_0000289 .

obo:NCBITaxon_61170 a rdfs:Class ;
  rdfs:label "Holdemania" ;
  rdfs:subClassOf obo:NCBITaxon_128827 .

obo:BFO_0000035 a rdfs:Class ;
  rdfs:label "process boundary"@en ;
  rdfs:comment "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:NCBITaxon_1689 a rdfs:Class ;
  rdfs:label "Bifidobacterium dentium" ;
  rdfs:subClassOf obo:NCBITaxon_1678 .

obo:OHMI_0000527 a rdfs:Class ;
  rdfs:label "expansion of Solobacterium in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Solobacterium up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_1720 a rdfs:Class ;
  rdfs:label "Corynebacterium sp." ;
  rdfs:subClassOf obo:NCBITaxon_1716 .

obo:NCBITaxon_32523 a rdfs:Class ;
  rdfs:label "Tetrapoda" ;
  rdfs:subClassOf obo:NCBITaxon_117571 .

obo:OHMI_0000158 a rdfs:Class ;
  rdfs:label "depletion of Coprobacillus in PsA human gut"@en ;
  rdfs:comment "a PsA human-gut microbiome interaction that shows an decrease of Coprobacillus in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000152 .

obo:OHMI_0000873 a rdfs:Class ;
  rdfs:label "depletion of Sutterella in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Sutterella down-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_213121 a rdfs:Class ;
  rdfs:label "Desulfobulbaceae" ;
  rdfs:subClassOf obo:NCBITaxon_200940 .

obo:OHMI_0000331 a rdfs:Class ;
  rdfs:label "expansion of Roseburia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Roseburia is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:OHMI_0000923 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidetes in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroidetes up-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000225 a rdfs:Class ;
  rdfs:label "expansion of Porphyromonas macacae in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of Porphyromonas macacae in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000099 .

obo:OHMI_0000290 a rdfs:Class ;
  rdfs:label "expansion of Beggiatoa in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Beggiatoa is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:DOID_2914 a rdfs:Class ;
  rdfs:label "immune system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in the immune system." ;
  rdfs:subClassOf obo:DOID_7 .

obo:PCO_0000023 a rdfs:Class ;
  rdfs:label "community species evenness"@en ;
  rdfs:comment "A quality of an ecological community that reflects how close in abundance all species in a community are."@en ;
  rdfs:subClassOf obo:PCO_0000004 .

obo:NCBITaxon_32066 a rdfs:Class ;
  rdfs:label "Fusobacteriota" ;
  rdfs:subClassOf obo:NCBITaxon_2 .

obo:DOID_1793 a rdfs:Class ;
  rdfs:label "pancreatic cancer" ;
  rdfs:comment "An endocrine gland cancer located_in the pancreas." ;
  rdfs:subClassOf obo:DOID_170 .

obo:NCBITaxon_9989 a rdfs:Class ;
  rdfs:label "Rodentia" ;
  rdfs:subClassOf obo:NCBITaxon_314146 .

obo:OHMI_0000464 a rdfs:Class ;
  rdfs:label "pH value"@en ;
  rdfs:comment "A measurement datum that is a logarithmic scale used to specify the acidity or basicity of an aqueous solution. It is the negative of the base 10 logarithm of the activity of the hydrogen ion. At 25 °C, solutions with a pH less than 7 are acidic and solutions with a pH greater than 7 are basic." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OHMI_0000027 a rdfs:Class ;
  rdfs:label "restoring human gut microbiome resistance to C. difficile infection by fecal microbiota transplantation"@en ;
  rdfs:comment "A human-gut microbiome interaction where a fecal microbiota transplantation is used to restore a human gut microbiome to a state resistant to Clostridium difficile infection." ;
  rdfs:subClassOf obo:OHMI_0000025 .

obo:OHMI_0000647 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidaceae in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Bacteroidaceae up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:NCBITaxon_44689 a rdfs:Class ;
  rdfs:label "Dictyostelium discoideum" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:OHMI_0000707 a rdfs:Class ;
  rdfs:label "expansion of Megasphaera elsdenii DSM20460 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Megasphaera elsdenii DSM20460 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000479 a rdfs:Class ;
  rdfs:label "differentially enriched microbial marker for dysbiosis"@en ;
  rdfs:comment "A microbe that is differentially enriched in a microbiome host and can serve as a marker for a dysbiosis" ;
  rdfs:subClassOf obo:OHMI_0000460 .

obo:OHMI_0000793 a rdfs:Class ;
  rdfs:label "depletion of Fusicatenibacter saccharivorans in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Fusicatenibacter saccharivorans down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000754 a rdfs:Class ;
  rdfs:label "expansion of Oscillibacter in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Oscillibacter up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_2049 a rdfs:Class ;
  rdfs:label "Actinomycetaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1760 .

obo:OHMI_0000073 a rdfs:Class ;
  rdfs:label "depletion of Dialister in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows a depletion of Dialister in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000053 .

obo:NCBITaxon_2810280 a rdfs:Class ;
  rdfs:label "Coprobacillaceae" ;
  rdfs:subClassOf obo:NCBITaxon_526525 .

obo:OHMI_0000070 a rdfs:Class ;
  rdfs:label "expansion of Clostridia in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Clostridia in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000122 a rdfs:Class ;
  rdfs:label "PsA human zone of skin microbiome interaction"@en ;
  rdfs:comment "A human  skin microbiome interaction that is associated with  psoriatic arthritis (PsA)." ;
  rdfs:subClassOf obo:OHMI_0000121 .

obo:NCBITaxon_186802 a rdfs:Class ;
  rdfs:label "Eubacteriales" ;
  rdfs:subClassOf obo:NCBITaxon_186801 .

obo:NCBITaxon_713 a rdfs:Class ;
  rdfs:label "Actinobacillus" ;
  rdfs:subClassOf obo:NCBITaxon_712 .

obo:NCBITaxon_201174 a rdfs:Class ;
  rdfs:label "Actinomycetota" ;
  rdfs:subClassOf obo:NCBITaxon_1783272 .

obo:NCBITaxon_329854 a rdfs:Class ;
  rdfs:label "Bacteroides intestinalis" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:OHMI_0000294 a rdfs:Class ;
  rdfs:label "expansion of Crenothrix in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Crenothrix is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:OHMI_0000285 a rdfs:Class ;
  rdfs:label "expansion of Fusobacteria in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacteria is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000765 a rdfs:Class ;
  rdfs:label "expansion of Veillonellaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Veillonellaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_341694 a rdfs:Class ;
  rdfs:label "Peptostreptococcus stomatis" ;
  rdfs:subClassOf obo:NCBITaxon_1257 .

obo:OHMI_0000595 a rdfs:Class ;
  rdfs:label "depletion of Bacteroidia in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Bacteroidia down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000868 a rdfs:Class ;
  rdfs:label "depletion of Anaerostipes in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Anaerostipes down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000064 a rdfs:Class ;
  rdfs:label "expansion of Porphyromonas gingivalis in RA human oral cavity"@en ;
  rdfs:comment "a  RA human oral cavity  microbiome interaction that shows an expansion of Porphyromonas gingivalis in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:PCO_0000063 a rdfs:Class ;
  rdfs:label "Simpson diversity index"@en ;
  rdfs:comment "A community species diversity metric that is quantified via the following formula: the reciprocal of the sum of squared proportion of species i relative to the total number of species (pi)." ;
  rdfs:subClassOf obo:PCO_0000019 .

obo:NCBITaxon_31969 a rdfs:Class ;
  rdfs:label "Mollicutes" ;
  rdfs:subClassOf obo:NCBITaxon_544448 .

obo:OHMI_0000274 a rdfs:Class ;
  rdfs:label "expansion of Akkermansia muciniphila in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Akkermansia muciniphila in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000255 .

obo:OHMI_0000930 a rdfs:Class ;
  rdfs:label "depletion of Hungatella in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Hungatella down-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000155 a rdfs:Class ;
  rdfs:label "depletion of Pseudobutyrivibrio in PsA human gut"@en ;
  rdfs:comment "a PsA human-gut microbiome interaction that shows an decrease of Pseudobutyrivibrio in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000152 .

obo:OHMI_0000448 a rdfs:Class ;
  rdfs:label "expansion of C. hiranonis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where [Clostridium] hiranonis  is increased." ;
  rdfs:subClassOf obo:OHMI_0000369 .

obo:OHMI_0000374 a rdfs:Class ;
  rdfs:label "expansion of Erysipelotrichaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Erysipelotrichaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_306 a rdfs:Class ;
  rdfs:label "Pseudomonas sp." ;
  rdfs:subClassOf obo:NCBITaxon_286 .

obo:IAO_8000016 a rdfs:Class ;
  rdfs:label "taxonomic bridge ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000004 .

obo:OHMI_0000606 a rdfs:Class ;
  rdfs:label "depletion of Bulleidia in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Bulleidia down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000792 a rdfs:Class ;
  rdfs:label "depletion of Anaerostipes hadrus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Anaerostipes hadrus down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:DOID_9008 a rdfs:Class ;
  rdfs:label "psoriatic arthritis" ;
  rdfs:comment "A syndrome that occurs in humans with psoriasis who also experience symptoms similar to arthritis." ;
  rdfs:subClassOf obo:DOID_848 .

obo:NCBITaxon_84642 a rdfs:Class ;
  rdfs:label "Aeromonadaceae" ;
  rdfs:subClassOf obo:NCBITaxon_135624 .

obo:NCBITaxon_543314 a rdfs:Class ;
  rdfs:label "Anaerovoracaceae" ;
  rdfs:subClassOf obo:NCBITaxon_3082720 .

obo:NCBITaxon_100883 a rdfs:Class ;
  rdfs:label "Coprobacillus" ;
  rdfs:subClassOf obo:NCBITaxon_2810280 .

obo:OHMI_0000729 a rdfs:Class ;
  rdfs:label "expansion of Enterobacterales in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Enterobacterales up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_820 a rdfs:Class ;
  rdfs:label "Bacteroides uniformis" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:CHEBI_33696 a rdfs:Class ;
  rdfs:label "nucleic acid" ;
  rdfs:comment "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ;
  rdfs:subClassOf obo:CHEBI_33839 .

obo:OHMI_0000909 a rdfs:Class ;
  rdfs:label "depletion of Agathobacter rectalis in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Agathobacter rectalis down-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:IAO_8000001 a rdfs:Class ;
  rdfs:label "base ontology module"@en ;
  rdfs:comment "An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies."@en ;
  rdfs:seeAlso <https://github.com/INCATools/ontology-starter-kit/issues/50> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OHMI_0000787 a rdfs:Class ;
  rdfs:label "depletion of Shewanella livingstonensis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Shewanella livingstonensis down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_848 a rdfs:Class ;
  rdfs:label "Fusobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_203492 .

obo:NCBITaxon_90371 a rdfs:Class ;
  rdfs:label "Salmonella enterica subsp. enterica serovar Typhimurium" ;
  rdfs:subClassOf obo:NCBITaxon_59201 .

obo:NCBITaxon_28211 a rdfs:Class ;
  rdfs:label "Alphaproteobacteria" ;
  rdfs:subClassOf obo:NCBITaxon_1224 .

obo:DOID_9074 a rdfs:Class ;
  rdfs:label "systemic lupus erythematosus" ;
  rdfs:comment "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart." ;
  rdfs:subClassOf obo:DOID_1575 .

obo:NCBITaxon_2070 a rdfs:Class ;
  rdfs:label "Pseudonocardiaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1760 .

obo:OHMI_0000385 a rdfs:Class ;
  rdfs:label "expansion of Proteus mirabilis in RA human urine"@en ;
  rdfs:comment "a RA human-urine microbiome interaction that shows an expansion of Proteus mirabilis in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000345 .

obo:OHMI_0000695 a rdfs:Class ;
  rdfs:label "expansion of Leptospira kmetyi in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Leptospira kmetyi up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:CHEBI_33839 a rdfs:Class ;
  rdfs:label "macromolecule" ;
  rdfs:comment "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OHMI_0000912 a rdfs:Class ;
  rdfs:label "depletion of Sutterella in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Sutterella down-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:IAO_8000012 a rdfs:Class ;
  rdfs:label "species subset ontology module"@en ;
  rdfs:comment "A subset ontology that is crafted to either include or exclude a taxonomic grouping of species."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OHMI_0000636 a rdfs:Class ;
  rdfs:label "GOLD Stage 3"@en ;
  rdfs:comment "GOLD Stage 3 (Severe) COPD indicates a significant limitation in lung function, with between 30% and 49% of the predicted value. Patients typically experience worsening shortness of breath, frequent exacerbations (flare-ups), and reduced exercise tolerance, requiring targeted treatment such as pulmonary rehabilitation and inhaled medications." ;
  rdfs:subClassOf obo:OHMI_0000490 .

obo:NCBITaxon_67825 a rdfs:Class ;
  rdfs:label "Citrobacter rodentium" ;
  rdfs:subClassOf obo:NCBITaxon_544 .

obo:OHMI_0000456 a rdfs:Class ;
  rdfs:label "expansion of F. nucleatum subsp. vincentii in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacterium nucleatum subsp. vincentii is increased." ;
  rdfs:subClassOf obo:OHMI_0000289 .

obo:BFO_0000020 a rdfs:Class ;
  rdfs:label "specifically dependent continuant"@en ;
  rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:NCBITaxon_3025755 a rdfs:Class ;
  rdfs:label "Thomasclavelia" ;
  rdfs:subClassOf obo:NCBITaxon_2810280 .

obo:OHMI_0000517 a rdfs:Class ;
  rdfs:label "expansion of Actinomyces in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Actinomyces up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000863 a rdfs:Class ;
  rdfs:label "depletion of Bacteroides in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroides down-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:OHMI_0000603 a rdfs:Class ;
  rdfs:label "depletion of Mogibacterium in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Mogibacterium down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_186824 a rdfs:Class ;
  rdfs:label "Thermoactinomycetaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1385 .

obo:OHMI_0000597 a rdfs:Class ;
  rdfs:label "depletion of Moraxella  in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Moraxella  down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_724 a rdfs:Class ;
  rdfs:label "Haemophilus" ;
  rdfs:subClassOf obo:NCBITaxon_712 .

obo:UPHENO_0001001 a rdfs:Class ;
  rdfs:label "phenotype"@en ;
  rdfs:subClassOf obo:BFO_0000019 , obo:PATO_0000001 .

obo:OBI_0001137 a rdfs:Class ;
  rdfs:label "protein sequencer" ;
  rdfs:comment "An device that is used to determine the order of amino acids in protein sequences." ;
  rdfs:subClassOf obo:OBI_0000832 .

obo:OHMI_0000053 a rdfs:Class ;
  rdfs:label "SLE human-gut microbiome interaction"@en ;
  rdfs:comment "A human gut-microbiome interaction that is associated with systemic lupus erythematosus (SLE)." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:OHMI_0000263 a rdfs:Class ;
  rdfs:label "expansion of Badula fragilis in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Badula fragilis in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000255 .

obo:OHMI_0000856 a rdfs:Class ;
  rdfs:label "expansion of Acidaminococcaceae in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Acidaminococcaceae up-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_84111 a rdfs:Class ;
  rdfs:label "Eggerthella" ;
  rdfs:subClassOf obo:NCBITaxon_1643826 .

obo:UBERON_0000174 a rdfs:Class ;
  rdfs:label "excreta" ;
  rdfs:comment "A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity" ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OHMI_0000528 a rdfs:Class ;
  rdfs:label "expansion of Veillonellaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Veillonellaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_28216 a rdfs:Class ;
  rdfs:label "Betaproteobacteria" ;
  rdfs:subClassOf obo:NCBITaxon_1224 .

obo:DOID_17 a rdfs:Class ;
  rdfs:label "musculoskeletal system disease" ;
  rdfs:comment "A disease of anatomical entity that occurs in the muscular and/or skeletal system." ;
  rdfs:subClassOf obo:DOID_7 .

obo:OHMI_0000675 a rdfs:Class ;
  rdfs:label "bacterial change in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "MDD human gut microbiome interaction that shows an change of bacteria in patients with active-phase MDD compared to healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000672 .

obo:PCO_0000082 a rdfs:Class ;
  rdfs:label "seedling density of an ecological community"@en ;
  rdfs:comment "The density of seedlings in an ecological community (multiple species), often measured as the number of plants per area." ;
  rdfs:subClassOf obo:PCO_0000004 , obo:PCO_0000078 .

obo:OHMI_0000393 a rdfs:Class ;
  rdfs:label "depletion of Bifidobacterium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bifidobacterium is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_2719313 a rdfs:Class ;
  rdfs:label "Enterocloster" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_580596 a rdfs:Class ;
  rdfs:label "Butyricicoccus" ;
  rdfs:subClassOf obo:NCBITaxon_3085642 .

obo:OHMI_0000169 a rdfs:Class ;
  rdfs:label "depletion of Malassezia sympodialis in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an decrease of Malassezia sympodialis in patients with  PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000122 .

obo:NCBITaxon_239935 a rdfs:Class ;
  rdfs:label "Akkermansia muciniphila" ;
  rdfs:subClassOf obo:NCBITaxon_239934 .

obo:PATO_0000047 a rdfs:Class ;
  rdfs:label "biological sex" ;
  rdfs:comment "An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:NCBITaxon_2614128 a rdfs:Class ;
  rdfs:label "unclassified Clostridium" ;
  rdfs:subClassOf obo:NCBITaxon_1485 .

obo:NCBITaxon_1982626 a rdfs:Class ;
  rdfs:label "Faecalibacillus intestinalis" ;
  rdfs:subClassOf obo:NCBITaxon_2810280 .

obo:OBI_0002117 a rdfs:Class ;
  rdfs:label "whole genome sequencing assay" ;
  rdfs:comment "A DNA sequencing assay that intends to provide information about the sequence of an entire genome of an organism." ;
  rdfs:subClassOf obo:OBI_0000626 .

obo:DOID_3118 a rdfs:Class ;
  rdfs:label "hepatobiliary disease" ;
  rdfs:comment "A gastrointestinal system disease that is located_in the liver and/or biliary tract." ;
  rdfs:subClassOf obo:DOID_77 .

obo:NCBITaxon_2759 a rdfs:Class ;
  rdfs:label "Eukaryota" ;
  rdfs:subClassOf obo:COB_0000022 .

obo:OHMI_0000857 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidota in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Bacteroidota up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_171551 a rdfs:Class ;
  rdfs:label "Porphyromonadaceae" ;
  rdfs:subClassOf obo:NCBITaxon_171549 .

obo:OHMI_0000038 a rdfs:Class ;
  rdfs:label "expansion of Prevotellaceae in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Prevotellaceae in patients with  chronic RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:NCBITaxon_29347 a rdfs:Class ;
  rdfs:label "[Clostridium] scindens" ;
  rdfs:subClassOf obo:NCBITaxon_1506553 .

obo:OHMI_0000686 a rdfs:Class ;
  rdfs:label "expansion of Phascolarctobacterium faecium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Phascolarctobacterium faecium up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000084 a rdfs:Class ;
  rdfs:label "depletion of Haemophilus in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity microbiome interaction that shows an decrease of Haemophilus in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:NCBITaxon_80840 a rdfs:Class ;
  rdfs:label "Burkholderiales" ;
  rdfs:subClassOf obo:NCBITaxon_28216 .

obo:OHMI_0000322 a rdfs:Class ;
  rdfs:label "depletion of P.ruminis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Pseudobutyrivibrio ruminis is decreased." ;
  rdfs:subClassOf obo:OHMI_0000346 .

obo:OHMI_0000615 a rdfs:Class ;
  rdfs:label "expansion of Nocardioides in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Nocardioides up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000490 a rdfs:Class ;
  rdfs:label "severity of COPD"@en ;
  rdfs:comment "Severity provided by the Global Initiative for Chronic Obstructive Lung Disease (“GOLD”) for indicating different severity levels of COPD." ;
  rdfs:subClassOf obo:PATO_0001236 .

obo:OHMI_0000513 a rdfs:Class ;
  rdfs:label "expansion of Nocardioides in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Nocardioides up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000781 a rdfs:Class ;
  rdfs:label "depletion of Dorea formicigenerans in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Dorea formicigenerans down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000818 a rdfs:Class ;
  rdfs:label "depletion of Lachnospira in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Lachnospira down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000437 a rdfs:Class ;
  rdfs:label "expansion of S. enterica in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Salmonella enterica is increased." ;
  rdfs:subClassOf obo:OHMI_0000401 .

obo:OHMI_0000330 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides fragilis in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Bacteroides fragilis in patients with RA compared with healthy controls. Bacteroides fragilis is a rare cause of septic arthritis." ;
  rdfs:subClassOf obo:OHMI_0000074 .

obo:OHMI_0000503 a rdfs:Class ;
  rdfs:label "expansion of Haemophilus parainfluenzae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Haemophilus parainfluenzae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000782 a rdfs:Class ;
  rdfs:label "depletion of Anaerobutyricum hallii in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Anaerobutyricum hallii down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000341 a rdfs:Class ;
  rdfs:label "expansion of Alistipes in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where ParaAlistipes is increased." ;
  rdfs:subClassOf obo:OHMI_0000305 .

obo:OHMI_0000829 a rdfs:Class ;
  rdfs:label "depletion of Barnesiellaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Barnesiellaceae down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000800 a rdfs:Class ;
  rdfs:label "depletion of Romboutsia timonensis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Romboutsia timonensis down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_1269 a rdfs:Class ;
  rdfs:label "Micrococcus"@en ;
  rdfs:subClassOf obo:NCBITaxon_1268 .

obo:NCBITaxon_570 a rdfs:Class ;
  rdfs:label "Klebsiella" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:OHMI_0000670 a rdfs:Class ;
  rdfs:label "bacterial change in sputum of severe COPD patient compared to mild-moderate COPD"@en ;
  rdfs:comment "A COPD human oral microbiome interaction that shows bacterial change in sputum of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:subClassOf obo:OHMI_0000494 .

obo:DOID_7 a rdfs:Class ;
  rdfs:label "disease of anatomical entity" ;
  rdfs:comment "A disease that manifests in a defined anatomical structure." ;
  rdfs:subClassOf obo:DOID_4 .

obo:OHMI_0000196 a rdfs:Class ;
  rdfs:label "mouse gut microbiome interaction"@en ;
  rdfs:comment "An interaction between musculus and gut microbiome." ;
  rdfs:subClassOf obo:OHMI_0000195 .

obo:OHMI_0000182 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides vulgatus in AS  rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with ankylosing spondylitis(AS) that shows an expansion of Bacteroides vulgatus in rattus with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000110 .

obo:NCBITaxon_32045 a rdfs:Class ;
  rdfs:label "Pseudomonadota incertae sedis" ;
  rdfs:subClassOf obo:NCBITaxon_1224 .

obo:OHMI_0000197 a rdfs:Class ;
  rdfs:label "SLE mouse-gut microbiome interaction" ;
  rdfs:comment "A musculus gut-microbiome interaction that is associated with system lupus erythematosus(SLE)." ;
  rdfs:subClassOf obo:OHMI_0000196 .

obo:NCBITaxon_1624 a rdfs:Class ;
  rdfs:label "Ligilactobacillus salivarius" ;
  rdfs:subClassOf obo:NCBITaxon_2767887 .

obo:OHMI_0000147 a rdfs:Class ;
  rdfs:label "depletion of Subdoligranulum in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Subdoligranulum in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000128 .

obo:NCBITaxon_716545 a rdfs:Class ;
  rdfs:label "saccharomyceta" ;
  rdfs:subClassOf obo:NCBITaxon_4890 , obo:OHMI_0000460 .

obo:OHMI_0000375 a rdfs:Class ;
  rdfs:label "expansion of Prevotellaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Prevotellaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000305 .

obo:OHMI_0000281 a rdfs:Class ;
  rdfs:label "expansion of Yersinia in reactive arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with reactive arthritis that shows an expansion of Yersinia in rattus with juvenile rheumatoid arthritis compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000280 .

obo:OHMI_0000621 a rdfs:Class ;
  rdfs:label "expansion of Desulfobacterales in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Desulfobacterales up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:NCBITaxon_89153 a rdfs:Class ;
  rdfs:label "[Clostridium] hylemonae" ;
  rdfs:subClassOf obo:NCBITaxon_1506553 .

obo:OHMI_0000102 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidaceae in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of Bacteroidaceae in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000099 .

obo:OBI_0100060 a rdfs:Class ;
  rdfs:label "cultured cell population" ;
  rdfs:comment "A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:NCBITaxon_1853231 a rdfs:Class ;
  rdfs:label "Odoribacteraceae" ;
  rdfs:subClassOf obo:NCBITaxon_171549 .

obo:NCBITaxon_195950 a rdfs:Class ;
  rdfs:label "Tannerella" ;
  rdfs:subClassOf obo:NCBITaxon_2005525 .

obo:OHMI_0000342 a rdfs:Class ;
  rdfs:label "expansion of B. ovatus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroides ovatus is increased." ;
  rdfs:subClassOf obo:OHMI_0000333 .

obo:OHMI_0000926 a rdfs:Class ;
  rdfs:label "depletion of Dialister in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Dialister down-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000105 a rdfs:Class ;
  rdfs:label "expansion of Klebsiella pneumoniae in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of Klebsiella pneumoniae in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000099 .

obo:OHMI_0000610 a rdfs:Class ;
  rdfs:label "depletion of Firmicutes in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Firmicutes down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000259 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Bacteroides in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000256 .

obo:NCBITaxon_6668 a rdfs:Class ;
  rdfs:label "Daphnia" ;
  rdfs:subClassOf obo:NCBITaxon_197562 .

obo:OHMI_0000240 a rdfs:Class ;
  rdfs:label "expansion of Prevotella oulorum in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity  microbiome interaction that shows an expansion of Prevotella oulorum in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000111 .

obo:OHMI_0000378 a rdfs:Class ;
  rdfs:label "depletion of Ruminococcaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Ruminococcaceae is decreased." ;
  rdfs:subClassOf obo:OHMI_0000353 .

obo:OHMI_0000270 a rdfs:Class ;
  rdfs:label "depletion of Lachnospiraceae in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an decrease of Lachnospiraceae in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000255 .

obo:OHMI_0000798 a rdfs:Class ;
  rdfs:label "depletion of Eubacterium sp. CAG:156 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Eubacterium sp. CAG:156 down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_815 a rdfs:Class ;
  rdfs:label "Bacteroidaceae" ;
  rdfs:subClassOf obo:NCBITaxon_171549 .

obo:OHMI_0000770 a rdfs:Class ;
  rdfs:label "expansion of Deinococcaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Deinococcaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_333367 a rdfs:Class ;
  rdfs:label "Enterocloster asparagiformis" ;
  rdfs:subClassOf obo:NCBITaxon_2719313 .

obo:NCBITaxon_909930 a rdfs:Class ;
  rdfs:label "Acidaminococcaceae" ;
  rdfs:subClassOf obo:NCBITaxon_909932 .

obo:OHMI_0000111 a rdfs:Class ;
  rdfs:label "expansion of Prevotella  in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity  microbiome interaction that shows an expansion of Prevotella in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:NCBITaxon_221102 a rdfs:Class ;
  rdfs:label "Moniliophthora" ;
  rdfs:subClassOf obo:NCBITaxon_5204 , obo:OHMI_0000460 .

obo:OHMI_0000653 a rdfs:Class ;
  rdfs:label "depletion of Veillonella in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Veillonella down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000460 a rdfs:Class ;
  rdfs:label "microbe"@en ;
  rdfs:comment "An organism or virus or viron that is too small to be viewed by the unaided eye." ;
  rdfs:subClassOf obo:COB_0000022 .

obo:OHMI_0000367 a rdfs:Class ;
  rdfs:label "expansion of Streptococcaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Streptococcaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000690 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides stercoris in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroides stercoris up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000734 a rdfs:Class ;
  rdfs:label "expansion of Flavonifractor in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Flavonifractor up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000524 a rdfs:Class ;
  rdfs:label "expansion of Erysipelotrichales in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Erysipelotrichales up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000631 a rdfs:Class ;
  rdfs:label "depletion of Actinobacillus in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Actinobacillus down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:NCBITaxon_3052230 a rdfs:Class ;
  rdfs:label "Hepacivirus hominis" ;
  rdfs:subClassOf obo:NCBITaxon_2559587 .

obo:NCBITaxon_714 a rdfs:Class ;
  rdfs:label "Aggregatibacter actinomycetemcomitans" ;
  rdfs:subClassOf obo:NCBITaxon_416916 .

obo:DOID_28 a rdfs:Class ;
  rdfs:label "endocrine system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body." ;
  rdfs:subClassOf obo:DOID_7 .

obo:OHMI_0000483 a rdfs:Class ;
  rdfs:label "microbiome-cancer interaction"@en ;
  rdfs:comment "An host-microbiome interaction that is associated with cancer" ;
  rdfs:subClassOf obo:OHMI_0000001 .

obo:NCBITaxon_133925 a rdfs:Class ;
  rdfs:label "Olsenella" ;
  rdfs:subClassOf obo:NCBITaxon_1643824 .

obo:OHMI_0000718 a rdfs:Class ;
  rdfs:label "expansion of Fenollaria timonensis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Fenollaria timonensis up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000100 a rdfs:Class ;
  rdfs:label "expansion of Ruminococcaceae in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of Ruminococcaceae in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000099 .

obo:OHMI_0000745 a rdfs:Class ;
  rdfs:label "expansion of Atopobium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Atopobium up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000899 a rdfs:Class ;
  rdfs:label "expansion of Gordonibacter in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Gordonibacter up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000099 a rdfs:Class ;
  rdfs:label "AS human-gut microbiome interaction"@en ;
  rdfs:comment "A human gut-microbiome interaction that is associated with ankylosing spondylitis (AS)." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:OHMI_0000096 a rdfs:Class ;
  rdfs:label "expansion of Escherichia coli in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Escherichia coli in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000681 a rdfs:Class ;
  rdfs:label "expansion of Phocaeicola vulgatus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Phocaeicola vulgatus up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000008 a rdfs:Class ;
  rdfs:label "fungal microbiome of skin"@en ;
  rdfs:comment "A fungal microbiome that is located in the skin of a host organism" ;
  rdfs:subClassOf obo:OHMI_0000006 .

obo:OBI_0400103 a rdfs:Class ;
  rdfs:label "DNA sequencer"@en ;
  rdfs:comment "A DNA sequencer is an instrument that determines the order of deoxynucleotides in deoxyribonucleic acid sequences."@en ;
  rdfs:subClassOf obo:OBI_0000832 .

obo:OHMI_0000043 a rdfs:Class ;
  rdfs:label "expansion of [Clostridium] asparagiforme in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of [Clostridium] asparagiforme in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000070 .

obo:NCBITaxon_39496 a rdfs:Class ;
  rdfs:label "Eubacterium ventriosum" ;
  rdfs:subClassOf obo:NCBITaxon_1730 .

obo:OHMI_0000389 a rdfs:Class ;
  rdfs:label "expansion of B. wadsworthia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bilophila wadsworthia is increased." ;
  rdfs:subClassOf obo:OHMI_0000396 .

obo:OHMI_0000905 a rdfs:Class ;
  rdfs:label "expansion of Tannerellaceae in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Tannerellaceae up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:IAO_8000005 a rdfs:Class ;
  rdfs:label "import ontology module"@en ;
  rdfs:comment "A subset ontology module that is intended to be imported from another ontology."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/extract> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OHMI_0000356 a rdfs:Class ;
  rdfs:label "depletion of Firmicutes in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Firmicutes is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:DOID_676 a rdfs:Class ;
  rdfs:label "juvenile rheumatoid arthritis" ;
  rdfs:comment "A rheumatoid arthritis that involves an autoimmune disease onset in children under 16 which attacks the healthy cells and tissue of located_in joint." ;
  rdfs:subClassOf obo:DOID_7148 .

obo:IAO_0000003 a rdfs:Class ;
  rdfs:label "measurement unit label"@en ;
  rdfs:comment "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:UBERON_0004907 a rdfs:Class ;
  rdfs:label "lower digestive tract" ;
  rdfs:comment "The region of the digestive tract extending from the beginning of the intestines to the anus[GO - gut definition]." ;
  rdfs:subClassOf obo:UBERON_0004921 .

obo:NCBITaxon_338188 a rdfs:Class ;
  rdfs:label "Bacteroides finegoldii" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:OHMI_0000311 a rdfs:Class ;
  rdfs:label "depletion of Eubacteriaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Eubacteriaceae is decreased." ;
  rdfs:subClassOf obo:OHMI_0000353 .

obo:IAO_0000109 a rdfs:Class ;
  rdfs:label "measurement datum"@en ;
  rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OHMI_0000019 a rdfs:Class ;
  rdfs:label "human-microbiome interaction"@en ;
  rdfs:comment "A host-microbiome interaction where the host is human" ;
  rdfs:subClassOf obo:OHMI_0000001 .

obo:NCBITaxon_292632 a rdfs:Class ;
  rdfs:label "Subdoligranulum" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:OHMI_0000740 a rdfs:Class ;
  rdfs:label "expansion of Oxalobacter in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Oxalobacter up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000837 a rdfs:Class ;
  rdfs:label "expansion of Streptococcus in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Streptococcus up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000136 a rdfs:Class ;
  rdfs:label "expansion of Pseudobutyrivibrio in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Pseudobutyrivibrio in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:OHMI_0000397 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidetes in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroidetes is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000852 a rdfs:Class ;
  rdfs:label "expansion of Enterobacteriaceae in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Enterobacteriaceae up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_730 a rdfs:Class ;
  rdfs:label "[Haemophilus] ducreyi" ;
  rdfs:subClassOf obo:NCBITaxon_724 .

obo:OHMI_0000771 a rdfs:Class ;
  rdfs:label "expansion of Paenibacillaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Paenibacillaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000540 a rdfs:Class ;
  rdfs:label "expansion of Peptostreptococcus in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Peptostreptococcus up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_586 a rdfs:Class ;
  rdfs:label "Providencia" ;
  rdfs:subClassOf obo:NCBITaxon_1903414 .

obo:NCBITaxon_33958 a rdfs:Class ;
  rdfs:label "Lactobacillaceae" ;
  rdfs:subClassOf obo:NCBITaxon_186826 .

obo:OHMI_0000412 a rdfs:Class ;
  rdfs:label "depletion of R. hominis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Roseburia hominis is decreased." ;
  rdfs:subClassOf obo:OHMI_0000346 .

obo:NCBITaxon_186803 a rdfs:Class ;
  rdfs:label "Lachnospiraceae" ;
  rdfs:subClassOf obo:NCBITaxon_186801 .

obo:OHMI_0000626 a rdfs:Class ;
  rdfs:label "depletion of Bacteroidetes in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Bacteroidetes down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000583 a rdfs:Class ;
  rdfs:label "expansion of Perlucidibaca in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Perlucidibaca up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_203692 a rdfs:Class ;
  rdfs:label "Spirochaetia" ;
  rdfs:subClassOf obo:NCBITaxon_203691 .

obo:OHMI_0000317 a rdfs:Class ;
  rdfs:label "depletion of P.copri in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Prevotella copri is decreased." ;
  rdfs:subClassOf obo:OHMI_0000336 .

obo:NCBITaxon_200795 a rdfs:Class ;
  rdfs:label "Chloroflexi"@en ;
  rdfs:subClassOf obo:NCBITaxon_1783272 .

obo:OHMI_0000642 a rdfs:Class ;
  rdfs:label "expansion of Enterobacteriaceae in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Enterobacteriaceae up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OBI_0000806 a rdfs:Class ;
  rdfs:label "material maintenance objective" ;
  rdfs:comment "An objective specification maintains some or all of the qualities of a material over time." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OHMI_0000848 a rdfs:Class ;
  rdfs:label "expansion of Flavonifractor in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Flavonifractor up-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_78535 a rdfs:Class ;
  rdfs:label "Streptococcus viridans" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:NCBITaxon_1578 a rdfs:Class ;
  rdfs:label "Lactobacillus" ;
  rdfs:subClassOf obo:NCBITaxon_33958 , obo:OHMI_0000671 .

obo:NCBITaxon_1239 a rdfs:Class ;
  rdfs:label "Bacillota" ;
  rdfs:subClassOf obo:NCBITaxon_1783272 .

obo:IAO_0000102 a rdfs:Class ;
  rdfs:label "data about an ontology part"@en ;
  rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_8000004 a rdfs:Class ;
  rdfs:label "bridge ontology module"@en ;
  rdfs:comment "An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/inter-anatomy-ontology-bridge-ontologies> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OHMI_0000054 a rdfs:Class ;
  rdfs:label "colorectal cancer human-gut microbiome interaction"@en ;
  rdfs:comment "A human-gut microbiome interaction that is associated with colorectal cancer." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:NCBITaxon_697899 a rdfs:Class ;
  rdfs:label "Escherichia coli ETEC TW03439" ;
  rdfs:subClassOf obo:NCBITaxon_562 .

obo:NCBITaxon_46206 a rdfs:Class ;
  rdfs:label "Pseudobutyrivibrio ruminis" ;
  rdfs:subClassOf obo:NCBITaxon_46205 .

obo:OHMI_0000193 a rdfs:Class ;
  rdfs:label "Lachnospiraceae depletion in arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis  that shows a depleted quantity of Lachnospiraceae in rattus with arthritis compared with healty controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:NCBITaxon_1903414 a rdfs:Class ;
  rdfs:label "Morganellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_91347 .

obo:NCBITaxon_1262884 a rdfs:Class ;
  rdfs:label "Eubacterium sp. CAG:202" ;
  rdfs:subClassOf obo:NCBITaxon_2624479 .

obo:NCBITaxon_41978 a rdfs:Class ;
  rdfs:label "Ruminococcus sp." ;
  rdfs:subClassOf obo:NCBITaxon_1263 .

obo:OHMI_0000065 a rdfs:Class ;
  rdfs:label "expansion of Proteus mirabilis in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Proteus mirabilis in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000024 a rdfs:Class ;
  rdfs:label "colon cancer human-gut microbiome interaction"@en ;
  rdfs:comment "A human-gut microbiome interaction that is associated with colon cancer." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:NCBITaxon_203492 a rdfs:Class ;
  rdfs:label "Fusobacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_203491 .

obo:OHMI_0000859 a rdfs:Class ;
  rdfs:label "expansion of Actinomycetota in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Actinomycetota up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:CMO_0002095 a rdfs:Class ;
  rdfs:label "serum immunoglobulin A level" ;
  rdfs:comment "The amount in a specified sample of serum of one or more types of immunoglobulin A (IgA), one of the most prevalent of the five classes of antibodies produced by the body. IgA is found in all secretions of the body and is the major antibody in the tears, saliva, and mucous membranes lining the intestines and bronchi, constituting an important factor in mucosal immunity." ;
  rdfs:subClassOf obo:CMO_0001276 .

obo:OHMI_0000657 a rdfs:Class ;
  rdfs:label "depletion of Lachnospiraceae in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Lachnospiraceae down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000117 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidales in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Bacteroidales in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000115 .

obo:OHMI_0000245 a rdfs:Class ;
  rdfs:label "expansion of Chloroflexi in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Chloroflexi in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:NCBITaxon_1279 a rdfs:Class ;
  rdfs:label "Staphylococcus" ;
  rdfs:subClassOf obo:NCBITaxon_1385 .

obo:OHMI_0000835 a rdfs:Class ;
  rdfs:label "expansion of Porphyromonas in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Porphyromonas up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000403 a rdfs:Class ;
  rdfs:label "depletion of B. animalis subsp. lactis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bifidobacterium animalis subsp. lactis is decreased." ;
  rdfs:subClassOf obo:OHMI_0000390 .

obo:OHMI_0000471 a rdfs:Class ;
  rdfs:label "obsolete alpha diversity"@en ;
  rdfs:comment "the mean species diversity in sites or habitats at a local scale" .

obo:NCBITaxon_642 a rdfs:Class ;
  rdfs:label "Aeromonas" ;
  rdfs:subClassOf obo:NCBITaxon_84642 .

obo:NCBITaxon_1613 a rdfs:Class ;
  rdfs:label "Limosilactobacillus fermentum" ;
  rdfs:subClassOf obo:NCBITaxon_2742598 .

obo:RO_0002577 a rdfs:Class ;
  rdfs:label "system" ;
  rdfs:comment "A material entity consisting of multiple components that are causally integrated." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OHMI_0000443 a rdfs:Class ;
  rdfs:label "expansion of Microbacterium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Microbacterium is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_588605 a rdfs:Class ;
  rdfs:label "Robinsoniella" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000841 a rdfs:Class ;
  rdfs:label "expansion of Anaerotruncus in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Anaerotruncus up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000207 a rdfs:Class ;
  rdfs:label "expansion of Dialister in AS human gut"@en ;
  rdfs:comment "an AS human-gut microbiome interaction that shows an expansion of Dialister in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000104 .

obo:OHMI_0000244 a rdfs:Class ;
  rdfs:label "expansion of Treponema in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity  microbiome interaction that shows an expansion of Treponema in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:OHMI_0000454 a rdfs:Class ;
  rdfs:label "expansion of F. nucleatum subsp. nucleatum in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacterium nucleatum subsp. nucleatum is increased." ;
  rdfs:subClassOf obo:OHMI_0000416 .

obo:NCBITaxon_189330 a rdfs:Class ;
  rdfs:label "Dorea" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000828 a rdfs:Class ;
  rdfs:label "depletion of Christensenellaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Christensenellaceae down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000465 a rdfs:Class ;
  rdfs:label "DMARD"@en ;
  rdfs:comment "A drug product that has its ability to alter the progression of a rheumatic disease." ;
  rdfs:subClassOf obo:DRON_00000005 .

obo:OHMI_0000234 a rdfs:Class ;
  rdfs:label "depletion of Prevotella pleuritidis in SLE human oral cavity"@en ;
  rdfs:comment "a SLE human oral cavity microbiome interaction that shows an decrease of Prevotella pleuritidis in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000082 .

obo:OHMI_0000016 a rdfs:Class ;
  rdfs:label "microbiome in human gastrointestinal system"@en ;
  rdfs:comment "a human microbiome that is located in a human gastrointestinal system" ;
  rdfs:subClassOf obo:OHMI_0000002 .

obo:DOID_4 a rdfs:Class ;
  rdfs:label "disease" ;
  rdfs:comment "A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism." ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:UBERON_0001005 a rdfs:Class ;
  rdfs:label "respiratory airway" ;
  rdfs:comment "An airway through which respiratory air passes in organisms." ;
  rdfs:subClassOf obo:UBERON_0000062 .

obo:NCBITaxon_216851 a rdfs:Class ;
  rdfs:label "Faecalibacterium" ;
  rdfs:subClassOf obo:NCBITaxon_216572 , obo:OHMI_0000671 .

obo:NCBITaxon_1583098 a rdfs:Class ;
  rdfs:label "Fusobacterium hwasookii" ;
  rdfs:subClassOf obo:NCBITaxon_848 .

obo:NCBITaxon_117563 a rdfs:Class ;
  rdfs:label "Granulicatella" ;
  rdfs:subClassOf obo:NCBITaxon_186826 .

obo:OHMI_0000255 a rdfs:Class ;
  rdfs:label "ERA human-gut microbiome interaction"@en ;
  rdfs:comment "A human gut-microbiome interaction that is associated with  juvenile rheumatoid arthritis (ERA)." ;
  rdfs:subClassOf obo:OHMI_0000021 .

obo:DOID_1575 a rdfs:Class ;
  rdfs:label "rheumatic disease" ;
  rdfs:comment "An autoimmune hypersensitivity disease that involves inflammation or pain in the muscles, joints, or fibrous tissue." ;
  rdfs:subClassOf obo:DOID_0060032 , obo:DOID_65 .

obo:NCBITaxon_31957 a rdfs:Class ;
  rdfs:label "Propionibacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_85009 .

obo:NCBITaxon_40544 a rdfs:Class ;
  rdfs:label "Sutterella" ;
  rdfs:subClassOf obo:NCBITaxon_995019 .

obo:OHMI_0000440 a rdfs:Class ;
  rdfs:label "expansion of Acinetobacter in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Acinetobacter is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:NCBITaxon_82202 a rdfs:Class ;
  rdfs:label "Centipeda <firmicutes>" ;
  rdfs:subClassOf obo:NCBITaxon_1843491 .

obo:IAO_8000009 a rdfs:Class ;
  rdfs:label "single layer subset ontology module"@en ;
  rdfs:comment "A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OHMI_0000351 a rdfs:Class ;
  rdfs:label "depletion of L. acidophilus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Lactobacillus acidophilus is decreased." ;
  rdfs:subClassOf obo:OHMI_0000379 .

obo:OHMI_0000400 a rdfs:Class ;
  rdfs:label "expansion of Campylobacter in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Campylobacter is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_256845 a rdfs:Class ;
  rdfs:label "Lentisphaerota" ;
  rdfs:subClassOf obo:NCBITaxon_1783257 .

obo:OHMI_0000915 a rdfs:Class ;
  rdfs:label "depletion of Pyramidobacter in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Pyramidobacter down-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000830 a rdfs:Class ;
  rdfs:label "depletion of Turicibacteraceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Turicibacteraceae down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_1280 a rdfs:Class ;
  rdfs:label "Staphylococcus aureus" ;
  rdfs:subClassOf obo:NCBITaxon_1279 .

obo:OHMI_0000229 a rdfs:Class ;
  rdfs:label "expansion of Flavonifractor in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an expansion of Flavonifractor in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000053 .

obo:OHMI_0000160 a rdfs:Class ;
  rdfs:label "depletion of Propionibacterium in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an decrease of Propionibacterium in patients with  PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000161 .

obo:PATO_0000001 a rdfs:Class ;
  rdfs:label "quality" ;
  rdfs:comment "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:OHMI_0000426 a rdfs:Class ;
  rdfs:label "expansion of Solobacterium sp. S4-A19 in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Solobacterium sp. S4-A19 is increased." ;
  rdfs:subClassOf obo:OHMI_0000295 .

obo:DOID_5295 a rdfs:Class ;
  rdfs:label "intestinal disease" ;
  rdfs:comment "A gastrointestinal system disease that is located_in the intestine." ;
  rdfs:subClassOf obo:DOID_77 .

obo:NCBITaxon_2974251 a rdfs:Class ;
  rdfs:label "Segatella" ;
  rdfs:subClassOf obo:NCBITaxon_171552 .

obo:NCBITaxon_200670 a rdfs:Class ;
  rdfs:label "Crenothrix" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:NCBITaxon_162289 a rdfs:Class ;
  rdfs:label "Peptoniphilus" ;
  rdfs:subClassOf obo:NCBITaxon_1570339 .

obo:OHMI_0000078 a rdfs:Class ;
  rdfs:label "RA human respiratory airway microbiome interaction"@en ;
  rdfs:comment "A human respiratory airway microbiome interaction that is associated with rheumatoid arthritis (RA)." ;
  rdfs:subClassOf obo:OHMI_0000077 .

obo:OBI_0000626 a rdfs:Class ;
  rdfs:label "DNA sequencing assay" ;
  rdfs:comment "A sequencing assay which determines information on the sequence of a DNA molecule." ;
  rdfs:subClassOf obo:OBI_0600047 .

obo:OHMI_0000817 a rdfs:Class ;
  rdfs:label "depletion of Paraprevotella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Paraprevotella down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000523 a rdfs:Class ;
  rdfs:label "expansion of Abiotrophia in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Abiotrophia up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000432 a rdfs:Class ;
  rdfs:label "expansion of E. coli B in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Escherichia coli B is increased." ;
  rdfs:subClassOf obo:OHMI_0000395 .

obo:OHMI_0000628 a rdfs:Class ;
  rdfs:label "depletion of Oribacterium in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Oribacterium down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:NCBITaxon_893 a rdfs:Class ;
  rdfs:label "Desulfobulbus" ;
  rdfs:subClassOf obo:NCBITaxon_213121 .

obo:OHMI_0000319 a rdfs:Class ;
  rdfs:label "depletion of D.formicigenerans in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Dorea formicigenerans is decreased." ;
  rdfs:subClassOf obo:OHMI_0000346 .

obo:OHMI_0000296 a rdfs:Class ;
  rdfs:label "expansion of Sulfurovum in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Sulfurovum is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000823 a rdfs:Class ;
  rdfs:label "depletion of Agathobacter in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Agathobacter down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000846 a rdfs:Class ;
  rdfs:label "expansion of Butyricimonas in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Butyricimonas up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000415 a rdfs:Class ;
  rdfs:label "expansion of H. hepaticus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Helicobacter hepaticus is increased." ;
  rdfs:subClassOf obo:OHMI_0000411 .

obo:OHMI_0000266 a rdfs:Class ;
  rdfs:label "depletion of Prevotella copri in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an decrease of Prevotella copri  in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000265 .

obo:DOID_5041 a rdfs:Class ;
  rdfs:label "esophageal cancer" ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the esophagus." ;
  rdfs:subClassOf obo:DOID_3119 .

obo:OHMI_0000233 a rdfs:Class ;
  rdfs:label "expansion of Eggerthella in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an expansion of Eggerthella in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000053 .

obo:OBI_0000015 a rdfs:Class ;
  rdfs:label "biological feature identification objective"@en ;
  rdfs:comment "Biological_feature_identification_objective is an objective role carried out by the proposition defining the aim of a study designed to examine or characterize a particular biological feature."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:NCBITaxon_192066 a rdfs:Class ;
  rdfs:label "Neisseria sp." ;
  rdfs:subClassOf obo:NCBITaxon_482 .

obo:NCBITaxon_186804 a rdfs:Class ;
  rdfs:label "Peptostreptococcaceae" ;
  rdfs:subClassOf obo:NCBITaxon_3082720 .

obo:NCBITaxon_487174 a rdfs:Class ;
  rdfs:label "Barnesiella intestinihominis" ;
  rdfs:subClassOf obo:NCBITaxon_397864 .

obo:OHMI_0000508 a rdfs:Class ;
  rdfs:label "expansion of Coribacteriales in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Coribacteriales up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:ENVO_01000254 a rdfs:Class ;
  rdfs:label "environmental system" ;
  rdfs:comment "A system which has the disposition to environ one or more material entities." ;
  rdfs:subClassOf obo:RO_0002577 .

obo:NCBITaxon_123375 a rdfs:Class ;
  rdfs:label "Solobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_128827 .

obo:OHMI_0000223 a rdfs:Class ;
  rdfs:label "expansion of Treponema denticola in AS human oral cavity"@en ;
  rdfs:comment "an AS human oral cavity  microbiome interaction that shows an expansion of rare taxa,Treponema denticola in patients with AS compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000106 .

obo:OHMI_0000482 a rdfs:Class ;
  rdfs:label "microbiome-gut-brain interaction"@en ;
  rdfs:comment "An host-microbiome interaction that involves the interaction between enteric microbiota on the host and the host brain (esp. the central nervous system), which often leads to a specific nervous phenotype" ;
  rdfs:subClassOf obo:OHMI_0000001 .

obo:NCBITaxon_1268 a rdfs:Class ;
  rdfs:label "Micrococcaceae" ;
  rdfs:subClassOf obo:NCBITaxon_85006 .

obo:OHMI_0000013 a rdfs:Class ;
  rdfs:label "microbiome in human lung"@en ;
  rdfs:comment "a human microbiome that is located in a human respiratory system" ;
  rdfs:subClassOf obo:OHMI_0000014 .

obo:OBI_0001902 a rdfs:Class ;
  rdfs:label "sample preparation for sequencing assay"@en ;
  rdfs:comment "A sample preparation for assay that preparation of nucleic acids for a sequencing assay" ;
  rdfs:subClassOf obo:OBI_0000073 .

obo:SO_0000001 a rdfs:Class ;
  rdfs:label "region" ;
  rdfs:comment "A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids." ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:OHMI_0000617 a rdfs:Class ;
  rdfs:label "expansion of Clostridium  in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Clostridium  up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000563 a rdfs:Class ;
  rdfs:label "expansion of Capnocytophaga in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Capnocytophaga up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_1298 a rdfs:Class ;
  rdfs:label "Deinococcus" ;
  rdfs:subClassOf obo:NCBITaxon_183710 .

obo:OHMI_0000042 a rdfs:Class ;
  rdfs:label "depletion of Megamonas hypermegale in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Megamonas hypermegale in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000005 a rdfs:Class ;
  rdfs:label "bacterial microbiome"@en ;
  rdfs:comment "A microbiome that includes a collective population of bacterial organisms." ;
  rdfs:subClassOf obo:OHMI_0000003 .

obo:OHMI_0000600 a rdfs:Class ;
  rdfs:label "depletion of Cardiobacteria in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Cardiobacteria down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_649756 a rdfs:Class ;
  rdfs:label "Anaerostipes hadrus" ;
  rdfs:subClassOf obo:NCBITaxon_207244 .

obo:IAO_0000032 a rdfs:Class ;
  rdfs:label "scalar measurement datum"@en ;
  rdfs:comment "a scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OHMI_0000587 a rdfs:Class ;
  rdfs:label "expansion of Comamonas in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Comamonas up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_4890 a rdfs:Class ;
  rdfs:label "Ascomycota" ;
  rdfs:subClassOf obo:NCBITaxon_451864 .

obo:OHMI_0000020 a rdfs:Class ;
  rdfs:label "human gut microbiome"@en ;
  rdfs:comment "A microbiome located in a human gut." ;
  rdfs:subClassOf obo:OHMI_0000016 .

obo:OHMI_0000498 a rdfs:Class ;
  rdfs:label "GOLD Stage 1"@en ;
  rdfs:comment "GOLD Stage 1 (Mild) is the initial stage of Chronic Obstructive Pulmonary Disease (COPD), characterized by mild airflow limitation with an (Forced Expiratory Volume in 1 second) 80% of the predicted value. While lung function is only slightly reduced, patients may experience chronic cough, sputum production, or occasional breathlessness." ;
  rdfs:subClassOf obo:OHMI_0000490 .

obo:NCBITaxon_1764 a rdfs:Class ;
  rdfs:label "Mycobacterium avium" ;
  rdfs:subClassOf obo:NCBITaxon_1763 .

obo:NCBITaxon_33025 a rdfs:Class ;
  rdfs:label "Phascolarctobacterium faecium" ;
  rdfs:subClassOf obo:NCBITaxon_33024 .

obo:OHMI_0000668 a rdfs:Class ;
  rdfs:label "COPD execerbation"@en ;
  rdfs:comment "A process quality in which the CODP disease is in its stage of execerbation." ;
  rdfs:subClassOf obo:OHMI_0000666 .

obo:NCBITaxon_1827 a rdfs:Class ;
  rdfs:label "Rhodococcus <high G+C Gram-positive bacteria>" ;
  rdfs:subClassOf obo:NCBITaxon_85025 .

obo:OHMI_0000638 a rdfs:Class ;
  rdfs:label "expansion of Actinobacteria in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Actinobacteria up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OBI_0001010 a rdfs:Class ;
  rdfs:label "nucleic acid extract" ;
  rdfs:comment "An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen." ;
  rdfs:subClassOf obo:OBI_0000423 , obo:OBI_0000953 .

obo:OHMI_0000261 a rdfs:Class ;
  rdfs:label "expansion of Klebsiella in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Klebsiella in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000257 .

obo:NCBITaxon_135624 a rdfs:Class ;
  rdfs:label "Aeromonadales" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OHMI_0000761 a rdfs:Class ;
  rdfs:label "expansion of Psychrobacter in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Psychrobacter up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000338 a rdfs:Class ;
  rdfs:label "depletion of Clostridiaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Clostridiaceae is decreased." ;
  rdfs:subClassOf obo:OHMI_0000353 .

obo:OHMI_0000526 a rdfs:Class ;
  rdfs:label "expansion of Bulleidia in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Bulleidia up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:ENVO_01001110 a rdfs:Class ;
  rdfs:label "ecosystem"@en ;
  rdfs:comment "An environmental system which includes both living and non-living components." ;
  rdfs:subClassOf obo:ENVO_01000254 .

obo:NCBITaxon_47715 a rdfs:Class ;
  rdfs:label "Lacticaseibacillus rhamnosus" ;
  rdfs:subClassOf obo:NCBITaxon_2759736 .

obo:NCBITaxon_1262880 a rdfs:Class ;
  rdfs:label "Eubacterium sp. CAG:156" ;
  rdfs:subClassOf obo:NCBITaxon_2624479 .

obo:OHMI_0000750 a rdfs:Class ;
  rdfs:label "expansion of Granulicatella in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Granulicatella up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000604 a rdfs:Class ;
  rdfs:label "depletion of Treponema in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Treponema down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_553174 a rdfs:Class ;
  rdfs:label "Prevotella melaninogenica ATCC 25845" ;
  rdfs:subClassOf obo:NCBITaxon_838 .

obo:NCBITaxon_1531 a rdfs:Class ;
  rdfs:label "Enterocloster clostridioformis" ;
  rdfs:subClassOf obo:NCBITaxon_2719313 .

obo:OHMI_0000362 a rdfs:Class ;
  rdfs:label "depletion of B. uniformis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroides uniformis is decreased." ;
  rdfs:subClassOf obo:OHMI_0000352 .

obo:OHMI_0000709 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides uniformis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroides uniformis up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:UBERON_0013765 a rdfs:Class ;
  rdfs:label "digestive system element" ;
  rdfs:comment "Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements." ;
  rdfs:subClassOf obo:UBERON_0000062 .

obo:OHMI_0000538 a rdfs:Class ;
  rdfs:label "expansion of Eubacterium in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Eubacterium up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000887 a rdfs:Class ;
  rdfs:label "expansion of Alistipes in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Alistipes up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_301301 a rdfs:Class ;
  rdfs:label "Roseburia hominis" ;
  rdfs:subClassOf obo:NCBITaxon_841 .

obo:OHMI_0000335 a rdfs:Class ;
  rdfs:label "expansion of A. muciniphila in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Akkermansia muciniphila is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000289 a rdfs:Class ;
  rdfs:label "expansion of Fusobacterium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacterium is increased." ;
  rdfs:subClassOf obo:OHMI_0000368 .

obo:OHMI_0000566 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillus in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Lactobacillus up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_1262828 a rdfs:Class ;
  rdfs:label "Clostridium sp. CAG:62" ;
  rdfs:subClassOf obo:NCBITaxon_2614128 .

obo:OHMI_0000918 a rdfs:Class ;
  rdfs:label "expansion of Barnesiella in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Barnesiella up-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000485 a rdfs:Class ;
  rdfs:label "host"@en ;
  rdfs:comment "An organism that has 'host role', i.e., a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism." ;
  rdfs:subClassOf obo:COB_0000022 .

obo:OHMI_0000839 a rdfs:Class ;
  rdfs:label "expansion of Alistipes in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Alistipes up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_413496 a rdfs:Class ;
  rdfs:label "Cronobacter" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:NCBITaxon_32207 a rdfs:Class ;
  rdfs:label "Rothia <high G+C Gram-positive bacteria>" ;
  rdfs:subClassOf obo:NCBITaxon_1268 .

obo:IAO_8000019 a rdfs:Class ;
  rdfs:label "ontology module subsetted by OWL profile"@en ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:NCBITaxon_572511 a rdfs:Class ;
  rdfs:label "Blautia" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000035 a rdfs:Class ;
  rdfs:label "decreased organism quantity compared with healthy controls"@en ;
  rdfs:comment "A quality with a depleted quantity of a type of organism (e.g., bacteria inside human gut) compared with control." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OHMI_0000549 a rdfs:Class ;
  rdfs:label "expansion of Aeromonadaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Aeromonadaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000250 a rdfs:Class ;
  rdfs:label "expansion of Nocardiaceae in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Nocardiaceae in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000249 .

obo:OBI_0000112 a rdfs:Class ;
  rdfs:label "specimen role"@en ;
  rdfs:comment "a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OHMI_0000278 a rdfs:Class ;
  rdfs:label "expansion of Malassezia furfur in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an expansion of Malassezia furfur in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000122 .

obo:NCBITaxon_2172004 a rdfs:Class ;
  rdfs:label "Lawsonibacter" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:OHMI_0000908 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacterium prausnitzii in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Faecalibacterium prausnitzii down-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000845 a rdfs:Class ;
  rdfs:label "expansion of Oscillibacter in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Oscillibacter up-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_1262816 a rdfs:Class ;
  rdfs:label "Clostridium sp. CAG:510" ;
  rdfs:subClassOf obo:NCBITaxon_2614128 .

obo:NCBITaxon_10116 a rdfs:Class ;
  rdfs:label "Rattus norvegicus" ;
  rdfs:subClassOf obo:NCBITaxon_10114 .

obo:NCBITaxon_1663 a rdfs:Class ;
  rdfs:label "Arthrobacter" ;
  rdfs:subClassOf obo:NCBITaxon_1268 .

obo:OHMI_0000824 a rdfs:Class ;
  rdfs:label "depletion of Clostridiaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Clostridiaceae down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_43996 a rdfs:Class ;
  rdfs:label "Catonella" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_662 a rdfs:Class ;
  rdfs:label "Vibrio" ;
  rdfs:subClassOf obo:NCBITaxon_641 .

obo:NCBITaxon_1783257 a rdfs:Class ;
  rdfs:label "PVC group" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:NCBITaxon_12916 a rdfs:Class ;
  rdfs:label "Acidovorax" ;
  rdfs:subClassOf obo:NCBITaxon_80864 .

obo:DOID_417 a rdfs:Class ;
  rdfs:label "autoimmune hypersensitivity disease" ;
  rdfs:comment "An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues." ;
  rdfs:subClassOf obo:DOID_2914 .

obo:OHMI_0000834 a rdfs:Class ;
  rdfs:label "depletion of Mycoplasmatota in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Mycoplasmatota down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000302 a rdfs:Class ;
  rdfs:label "expansion of Clostridiaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Clostridiaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:OHMI_0000884 a rdfs:Class ;
  rdfs:label "expansion of Alistipes onderdonkii in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Alistipes onderdonkii up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_76856 a rdfs:Class ;
  rdfs:label "Fusobacterium nucleatum subsp. nucleatum" ;
  rdfs:subClassOf obo:NCBITaxon_851 .

obo:OBI_0666666 a rdfs:Class ;
  rdfs:label "RNA extraction"@en ;
  rdfs:comment "A RNA extraction is a nucleic acid extraction where the desired output material is RNA"@en ;
  rdfs:subClassOf obo:OBI_0666667 .

obo:OHMI_0000649 a rdfs:Class ;
  rdfs:label "expansion of Klebsiella in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Klebsiella up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000474 a rdfs:Class ;
  rdfs:label "host microbiome restoration"@en ;
  rdfs:comment "A biological process that leads to the restoration of microbial community in a host organism" ;
  rdfs:subClassOf obo:GO_0008150 .

obo:NCBITaxon_33057 a rdfs:Class ;
  rdfs:label "Thauera" ;
  rdfs:subClassOf obo:NCBITaxon_28216 .

obo:NCBITaxon_7955 a rdfs:Class ;
  rdfs:label "Danio rerio" ;
  rdfs:subClassOf obo:NCBITaxon_117571 .

obo:OBI_0600047 a rdfs:Class ;
  rdfs:label "sequencing assay" ;
  rdfs:comment "An assay the uses chemical or biochemical means to infer the sequence of a biomaterial" ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:NCBITaxon_31979 a rdfs:Class ;
  rdfs:label "Clostridiaceae" ;
  rdfs:subClassOf obo:NCBITaxon_186802 .

obo:NCBITaxon_37632 a rdfs:Class ;
  rdfs:label "Amycolatopsis sp." ;
  rdfs:subClassOf obo:NCBITaxon_2070 .

obo:NCBITaxon_287 a rdfs:Class ;
  rdfs:label "Pseudomonas aeruginosa" ;
  rdfs:subClassOf obo:NCBITaxon_286 .

obo:NCBITaxon_104608 a rdfs:Class ;
  rdfs:label "Leptotrichia sp." ;
  rdfs:subClassOf obo:NCBITaxon_32067 .

obo:NCBITaxon_620 a rdfs:Class ;
  rdfs:label "Shigella" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:OHMI_0000813 a rdfs:Class ;
  rdfs:label "depletion of Pseudobutyrivibrio in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Pseudobutyrivibrio down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000106 a rdfs:Class ;
  rdfs:label "AS human oral cavity microbiome interaction"@en ;
  rdfs:comment "A human oral cavity microbiome interaction that is associated with  ankylosing spondylitis (AS)." ;
  rdfs:subClassOf obo:OHMI_0000036 .

obo:OHMI_0000555 a rdfs:Class ;
  rdfs:label "expansion of e-proteobacteria in lung of COPD patient compared to healthy human" ;
  rdfs:comment "e-proteobacteria up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000188 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillus murinus in arthritis  rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Lactobacillus murinus in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:OHMI_0000349 a rdfs:Class ;
  rdfs:label "expansion of Enterobacteriaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Enterobacteriaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000410 .

obo:NCBITaxon_200643 a rdfs:Class ;
  rdfs:label "Bacteroidia" ;
  rdfs:subClassOf obo:NCBITaxon_976 .

obo:OHMI_0000368 a rdfs:Class ;
  rdfs:label "expansion of Fusobacteriaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Fusobacteriaceae is increased." ;
  rdfs:subClassOf obo:OHMI_0000285 .

obo:NCBITaxon_1264 a rdfs:Class ;
  rdfs:label "Ruminococcus albus" ;
  rdfs:subClassOf obo:NCBITaxon_1263 .

obo:OHMI_0000812 a rdfs:Class ;
  rdfs:label "depletion of Dialister in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Dialister down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000396 a rdfs:Class ;
  rdfs:label "expansion of Bilophila in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bilophila is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000093 a rdfs:Class ;
  rdfs:label "expansion of Cryptobacterium curtum in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity microbiome interaction that shows an increase of Cryptobacterium curtum in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:NCBITaxon_596767 a rdfs:Class ;
  rdfs:label "Hydrogenoanaerobacterium" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:BFO_0000003 a rdfs:Class ;
  rdfs:label "occurrent"@en ;
  rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:CHEBI_33250 a rdfs:Class ;
  rdfs:label "atom" ;
  rdfs:comment "A chemical entity constituting the smallest component of an element having the chemical properties of the element." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OHMI_0000699 a rdfs:Class ;
  rdfs:label "expansion of Prevotella intermedia 17 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Prevotella intermedia 17 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_28116 a rdfs:Class ;
  rdfs:label "Bacteroides ovatus" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:OHMI_0000929 a rdfs:Class ;
  rdfs:label "depletion of Collinsella in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Collinsella down-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000515 a rdfs:Class ;
  rdfs:label "expansion of Rothia in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Rothia up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000177 a rdfs:Class ;
  rdfs:label "expansion of Actinomyces in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of Actinomyces in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:NCBITaxon_836 a rdfs:Class ;
  rdfs:label "Porphyromonas" ;
  rdfs:subClassOf obo:NCBITaxon_171551 .

obo:GO_0051701 a rdfs:Class ;
  rdfs:label "interaction with host" ;
  rdfs:comment "An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism." ;
  rdfs:subClassOf obo:GO_0044419 .

obo:NCBITaxon_468 a rdfs:Class ;
  rdfs:label "Moraxellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OHMI_0000577 a rdfs:Class ;
  rdfs:label "depletion of Thermoactinomyces in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Thermoactinomyces down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_547 a rdfs:Class ;
  rdfs:label "Enterobacter" ;
  rdfs:subClassOf obo:NCBITaxon_543 .

obo:DOID_170 a rdfs:Class ;
  rdfs:label "endocrine gland cancer" ;
  rdfs:comment "An organ system cancer located_in endocrine system that is characterized by uncontrolled cellular proliferation of the hormone producing glands of the endocrine system." ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_28 .

obo:NCBITaxon_292629 a rdfs:Class ;
  rdfs:label "Anaerolineales" ;
  rdfs:subClassOf obo:NCBITaxon_1783272 .

obo:OHMI_0000409 a rdfs:Class ;
  rdfs:label "expansion of K. pneumoniae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Klebsiella pneumoniae is increased." ;
  rdfs:subClassOf obo:OHMI_0000349 .

obo:CHEBI_16991 a rdfs:Class ;
  rdfs:label "deoxyribonucleic acid" ;
  rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." ;
  rdfs:subClassOf obo:CHEBI_33696 .

obo:OBI_0600012 a rdfs:Class ;
  rdfs:label "environmental material collection process"@en ;
  rdfs:comment "environmental_material_collection is an acquisition where an object is taken from an environment and put into a storage container. Roles include, environment, thing collected, container, acquirer."@en ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:OHMI_0000380 a rdfs:Class ;
  rdfs:label "depletion of B. longum in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bifidobacterium longum is decreased." ;
  rdfs:subClassOf obo:OHMI_0000393 .

obo:OHMI_0000089 a rdfs:Class ;
  rdfs:label "depletion of Rothia aeria in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity  microbiome interaction that shows an expansion of Rothia aeria in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:NCBITaxon_33213 a rdfs:Class ;
  rdfs:label "Bilateria" ;
  rdfs:subClassOf obo:NCBITaxon_33154 .

obo:NCBITaxon_371601 a rdfs:Class ;
  rdfs:label "Bacteroides xylanisolvens" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:OHMI_0000891 a rdfs:Class ;
  rdfs:label "expansion of Flavonifractor in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Flavonifractor up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000046 a rdfs:Class ;
  rdfs:label "decreased organism quantity in acute disease patient compared with chronic disease control"@en ;
  rdfs:comment "A quality with a depleted quantity of a type of organism (e.g., bacteria inside human gut) in a patient with an acute disease compared with a patient control with the same disease but at a chronic stage." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OHMI_0000497 a rdfs:Class ;
  rdfs:label "bacterial change in sputum of exacerbation COPD patient compared to stable COPD"@en ;
  rdfs:comment "A COPD human oral microbiome interaction that shows bacterial change in sputum of exacerbation COPD patient compared to stable COPD. Here the stable COPD means the ...." ;
  rdfs:subClassOf obo:OHMI_0000494 .

obo:NCBITaxon_244127 a rdfs:Class ;
  rdfs:label "Anaerotruncus" ;
  rdfs:subClassOf obo:NCBITaxon_216572 .

obo:OHMI_0000588 a rdfs:Class ;
  rdfs:label "expansion of Enterobacteriaceae in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Enterobacteriaceae up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000357 a rdfs:Class ;
  rdfs:label "depletion of Bacteroidetes in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bacteroidetes is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000876 a rdfs:Class ;
  rdfs:label "depletion of Pyramidobacter in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Pyramidobacter down-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:OHMI_0000706 a rdfs:Class ;
  rdfs:label "expansion of Prevotella denticola F0289 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Prevotella denticola F0289 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:IAO_8000015 a rdfs:Class ;
  rdfs:label "template generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated from a template specification and fillers for slots in that template."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/template> , <https://github.com/dosumis/dead_simple_owl_design_patterns/> , <https://doi.org/10.1186/s13326-017-0126-0> ;
  rdfs:subClassOf obo:IAO_8000014 .

obo:OHMI_0000049 a rdfs:Class ;
  rdfs:label "expansion of Lactobacillus sp in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Lactobacillus sp in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000803 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacillus intestinalis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Faecalibacillus intestinalis down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000552 a rdfs:Class ;
  rdfs:label "expansion of Desulfobacterales in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Desulfobacterales up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000679 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides fragilis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroides fragilis up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000512 a rdfs:Class ;
  rdfs:label "expansion of Olsenella in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Olsenella up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_909929 a rdfs:Class ;
  rdfs:label "Selenomonadales"@en ;
  rdfs:subClassOf obo:NCBITaxon_909932 .

obo:NCBITaxon_28025 a rdfs:Class ;
  rdfs:label "Bifidobacterium animalis" ;
  rdfs:subClassOf obo:NCBITaxon_1678 .

obo:OHMI_0000576 a rdfs:Class ;
  rdfs:label "depletion of Thermoactinomycetaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Thermoactinomycetaceae down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000218 a rdfs:Class ;
  rdfs:label "expansion of Pseudonocardia in RA human respiratory airway"@en ;
  rdfs:comment "RA human respiratory airway  microbiome interaction that shows an expansion of Pseudonocardia in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000078 .

obo:OHMI_0000825 a rdfs:Class ;
  rdfs:label "depletion of Prevotellaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Prevotellaceae down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000598 a rdfs:Class ;
  rdfs:label "depletion of Campylobacter in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Campylobacter down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000674 a rdfs:Class ;
  rdfs:label "bacterial change in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "MDD human gut microbiome interaction that shows an change of bacteria in patients with active-phase MDD compared to those with remission-phase MDD." ;
  rdfs:subClassOf obo:OHMI_0000672 .

obo:OHMI_0000110 a rdfs:Class ;
  rdfs:label "AS rat-gut microbiome interaction" ;
  rdfs:comment "A rattus gut-microbiome interaction that is associated with ankylosing spondylitis (AS)." ;
  rdfs:subClassOf obo:OHMI_0000095 .

obo:OHMI_0000883 a rdfs:Class ;
  rdfs:label "expansion of Alistipes finegoldii in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Alistipes finegoldii up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000914 a rdfs:Class ;
  rdfs:label "depletion of Howardella in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Howardella down-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_197 a rdfs:Class ;
  rdfs:label "Campylobacter jejuni" ;
  rdfs:subClassOf obo:NCBITaxon_194 .

obo:NCBITaxon_1730 a rdfs:Class ;
  rdfs:label "Eubacterium" ;
  rdfs:subClassOf obo:NCBITaxon_186806 .

obo:OHMI_0000314 a rdfs:Class ;
  rdfs:label "depletion of Microbacterium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Microbacterium is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_349741 a rdfs:Class ;
  rdfs:label "Akkermansia muciniphila ATCC BAA-835" ;
  rdfs:subClassOf obo:NCBITaxon_239935 .

obo:OHMI_0000518 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000545 a rdfs:Class ;
  rdfs:label "expansion of Fusobacterium in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Fusobacterium up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000931 a rdfs:Class ;
  rdfs:label "depletion of Agathobaculum in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Agathobaculum down-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000711 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium breve in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium breve up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000880 a rdfs:Class ;
  rdfs:label "depletion of Ruminococcaceae in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Ruminococcaceae down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_85004 a rdfs:Class ;
  rdfs:label "Bifidobacteriales" ;
  rdfs:subClassOf obo:NCBITaxon_1760 .

obo:OHMI_0000379 a rdfs:Class ;
  rdfs:label "depletion of Lactobacillaceae in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Lactobacillaceae is decreased." ;
  rdfs:subClassOf obo:OHMI_0000356 .

obo:NCBITaxon_472 a rdfs:Class ;
  rdfs:label "Acinetobacter sp." ;
  rdfs:subClassOf obo:NCBITaxon_469 .

obo:OHMI_0000143 a rdfs:Class ;
  rdfs:label "depletion of Faecalibacterium prausnitzii in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Faecalibacterium prausnitzii in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000128 .

obo:NCBITaxon_766764 a rdfs:Class ;
  rdfs:label "Debaryomycetaceae" ;
  rdfs:subClassOf obo:NCBITaxon_147537 .

obo:NCBITaxon_1354003 a rdfs:Class ;
  rdfs:label "Escherichia coli #1/H766" ;
  rdfs:subClassOf obo:NCBITaxon_562 .

obo:OHMI_0000836 a rdfs:Class ;
  rdfs:label "expansion of Phascolarctobacterium in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Phascolarctobacterium up-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_1760 a rdfs:Class ;
  rdfs:label "Actinomycetes" ;
  rdfs:subClassOf obo:NCBITaxon_201174 .

obo:HP_0002014 a rdfs:Class ;
  rdfs:label "Diarrhea" ;
  rdfs:comment "Abnormally increased frequency of loose or watery bowel movements." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:OHMI_0000534 a rdfs:Class ;
  rdfs:label "expansion of Catonella in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Catonella up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000605 a rdfs:Class ;
  rdfs:label "depletion of Aggregatibacter in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Aggregatibacter down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_239934 a rdfs:Class ;
  rdfs:label "Akkermansia" ;
  rdfs:subClassOf obo:NCBITaxon_74201 , obo:OHMI_0000671 .

obo:OHMI_0000625 a rdfs:Class ;
  rdfs:label "depletion of Veillonella in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Veillonella down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OBI_0100051 a rdfs:Class ;
  rdfs:label "specimen"@en ;
  rdfs:comment "A material entity that has the specimen role."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCBITaxon_209 a rdfs:Class ;
  rdfs:label "Helicobacter" ;
  rdfs:subClassOf obo:NCBITaxon_213849 .

obo:NCBITaxon_171552 a rdfs:Class ;
  rdfs:label "Prevotellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_171549 .

obo:OHMI_0000851 a rdfs:Class ;
  rdfs:label "expansion of Peptoniphilus in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Peptoniphilus up-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:DOID_3571 a rdfs:Class ;
  rdfs:label "liver cancer" ;
  rdfs:comment "A hepatobiliary system cancer that is located_in the liver." ;
  rdfs:subClassOf obo:DOID_0080355 , obo:DOID_170 , obo:DOID_409 .

obo:OHMI_0000614 a rdfs:Class ;
  rdfs:label "expansion of Proteobacteria in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Proteobacteria up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000814 a rdfs:Class ;
  rdfs:label "depletion of Anaerostipes in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Anaerostipes down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_2759736 a rdfs:Class ;
  rdfs:label "Lacticaseibacillus" ;
  rdfs:subClassOf obo:NCBITaxon_33958 .

obo:CHEBI_33697 a rdfs:Class ;
  rdfs:label "ribonucleic acid" ;
  rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." ;
  rdfs:subClassOf obo:CHEBI_33696 .

obo:OHMI_0000801 a rdfs:Class ;
  rdfs:label "depletion of Paraglaciecola sp. in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Paraglaciecola sp. down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_1335 a rdfs:Class ;
  rdfs:label "Streptococcus equinus" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:OHMI_0000325 a rdfs:Class ;
  rdfs:label "depletion of D. pneumosintes in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Dialister pneumosintes is decreased." ;
  rdfs:subClassOf obo:OHMI_0000356 .

obo:NCBITaxon_573 a rdfs:Class ;
  rdfs:label "Klebsiella pneumoniae" ;
  rdfs:subClassOf obo:NCBITaxon_570 .

obo:NCBITaxon_39948 a rdfs:Class ;
  rdfs:label "Dialister" ;
  rdfs:subClassOf obo:NCBITaxon_31977 .

obo:OHMI_0000904 a rdfs:Class ;
  rdfs:label "expansion of Burkholderiaceae in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Burkholderiaceae up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:NCBITaxon_508215 a rdfs:Class ;
  rdfs:label "Rothia <eudicots>" ;
  rdfs:subClassOf obo:NCBITaxon_71275 .

obo:OHMI_0000694 a rdfs:Class ;
  rdfs:label "expansion of Enterocloster aldensis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Enterocloster aldensis up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000192 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidaceae in arthritis rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Bacteroidaceae in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:NCBITaxon_1236 a rdfs:Class ;
  rdfs:label "Gammaproteobacteria" ;
  rdfs:subClassOf obo:NCBITaxon_1224 .

obo:OHMI_0000753 a rdfs:Class ;
  rdfs:label "expansion of Adlercreutzia in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Adlercreutzia up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000794 a rdfs:Class ;
  rdfs:label "depletion of Streptococcus rubneri in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Streptococcus rubneri down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000215 a rdfs:Class ;
  rdfs:label "depletion of Treponema in RA human respiratory airway"@en ;
  rdfs:comment "RA human respiratory airway microbiome interaction that shows an decrease of Treponema in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000078 .

obo:OBI_0000456 a rdfs:Class ;
  rdfs:label "material transformation objective"@en ;
  rdfs:comment "an objective specifiction that creates an specific output object from input materials."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OHMI_0000308 a rdfs:Class ;
  rdfs:label "depletion of Kluyvera in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Kluyvera is decreased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OBI_0600005 a rdfs:Class ;
  rdfs:label "collecting specimen from organism"@en ;
  rdfs:comment "a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation"@en ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:PCO_0000000 a rdfs:Class ;
  rdfs:label "collection of organisms"@en ;
  rdfs:comment "A material entity that consists of two or more organisms, viruses, or viroids."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCBITaxon_1300 a rdfs:Class ;
  rdfs:label "Streptococcaceae" ;
  rdfs:subClassOf obo:NCBITaxon_186826 .

obo:OHMI_0000620 a rdfs:Class ;
  rdfs:label "expansion of Desulfobulbaceae in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Desulfobulbaceae up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:DOID_13250 a rdfs:Class ;
  rdfs:label "diarrhea" ;
  rdfs:comment "A gastrointestinal system disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea: secretory diarrhea, osmotic diarrhea, motility-related diarrhea, and inflammatory diarrhea." ;
  rdfs:subClassOf obo:DOID_77 .

obo:OHMI_0000786 a rdfs:Class ;
  rdfs:label "depletion of Fusobacterium sp. in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Fusobacterium sp. down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000082 a rdfs:Class ;
  rdfs:label "SLE human oral cavity microbiome interaction"@en ;
  rdfs:comment "A human oral cavity microbiome interaction that is associated with  systemic lupus erythematosus  (SLE)." ;
  rdfs:subClassOf obo:OHMI_0000036 .

obo:UPHENO_0001002 a rdfs:Class ;
  rdfs:label "abnormal phenotype"@en ;
  rdfs:subClassOf obo:UPHENO_0001001 .

obo:OHMI_0000295 a rdfs:Class ;
  rdfs:label "expansion of Solobacterium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Solobacterium is increased." ;
  rdfs:subClassOf obo:OHMI_0000374 .

obo:NCBITaxon_407 a rdfs:Class ;
  rdfs:label "Methylobacterium"@en ;
  rdfs:subClassOf obo:NCBITaxon_119045 .

obo:NCBITaxon_46228 a rdfs:Class ;
  rdfs:label "[Ruminococcus] lactaris" ;
  rdfs:subClassOf obo:NCBITaxon_2316020 .

obo:NCBITaxon_580024 a rdfs:Class ;
  rdfs:label "Enterorhabdus" ;
  rdfs:subClassOf obo:NCBITaxon_1643826 .

obo:NCBITaxon_1502 a rdfs:Class ;
  rdfs:label "Clostridium perfringens" ;
  rdfs:subClassOf obo:NCBITaxon_1485 .

obo:OHMI_0000516 a rdfs:Class ;
  rdfs:label "expansion of Actinomycetaceae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Actinomycetaceae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_32205 a rdfs:Class ;
  rdfs:label "Leptonema <spirochetes>" ;
  rdfs:subClassOf obo:NCBITaxon_170 .

obo:NCBITaxon_1088106 a rdfs:Class ;
  rdfs:label "Badula fragilis" ;
  rdfs:subClassOf obo:NCBITaxon_1437201 .

obo:OHMI_0000685 a rdfs:Class ;
  rdfs:label "expansion of Bacteroides ovatus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bacteroides ovatus up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:DOID_65 a rdfs:Class ;
  rdfs:label "connective tissue disease" ;
  rdfs:comment "A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage." ;
  rdfs:subClassOf obo:DOID_17 .

obo:OBI_0000257 a rdfs:Class ;
  rdfs:label "DNA extraction"@en ;
  rdfs:comment "A DNA extraction is a nucleic acid extraction where the desired output material is DNA."@en ;
  rdfs:subClassOf obo:OBI_0666667 .

obo:OHMI_0000226 a rdfs:Class ;
  rdfs:label "Rikenellaceae depletion in AS rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with ankylosing spondylitis(AS) that shows a depleted quantity of Rikenellaceae in rattus with AS compared with healty controls." ;
  rdfs:subClassOf obo:OHMI_0000110 .

obo:OHMI_0000806 a rdfs:Class ;
  rdfs:label "depletion of Arsenophonus apicola in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Arsenophonus apicola down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:PCO_0000062 a rdfs:Class ;
  rdfs:label "Shannon diversity index"@en ;
  rdfs:comment "A community species diversity metric that accounts for both the abundance and evenness of the species present quantified via the following formula: the negative sum of, the product of the proportion of species i relative to the total number of species (pi) multiplied by the natural logarithm of this proportion (ln pi)." ;
  rdfs:subClassOf obo:PCO_0000019 .

obo:OHMI_0000496 a rdfs:Class ;
  rdfs:label "bacterial change in gut of COPD patient compared to healthy human"@en ;
  rdfs:subClassOf obo:OHMI_0000491 .

obo:NCBITaxon_85023 a rdfs:Class ;
  rdfs:label "Microbacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_85006 .

obo:OHMI_0000764 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacteriaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bifidobacteriaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_36470 a rdfs:Class ;
  rdfs:label "Streptococcus sp. 'group A'" ;
  rdfs:subClassOf obo:NCBITaxon_1301 .

obo:OHMI_0000559 a rdfs:Class ;
  rdfs:label "expansion of Dysgonomonas in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Dysgonomonas up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:DOID_9256 a rdfs:Class ;
  rdfs:label "colorectal cancer" ;
  rdfs:comment "A large intestine cancer that is located_in the colon and/or located_in the rectum." ;
  rdfs:subClassOf obo:DOID_5672 .

obo:OHMI_0000173 a rdfs:Class ;
  rdfs:label "depletion of Aggregatibacter in RA human oral cavity"@en ;
  rdfs:comment "a RA human oral cavity microbiome interaction that shows an decrease of Aggregatibacter in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000083 .

obo:OHMI_0000529 a rdfs:Class ;
  rdfs:label "expansion of Dialister in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Dialister up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000273 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Bifidobacterium in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000085 , obo:OHMI_0000255 .

obo:OHMI_0000392 a rdfs:Class ;
  rdfs:label "depletion of Ruminococcus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Ruminococcus is decreased." ;
  rdfs:subClassOf obo:OHMI_0000378 .

obo:OHMI_0000925 a rdfs:Class ;
  rdfs:label "depletion of Haemophilus in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Haemophilus down-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:OHMI_0000775 a rdfs:Class ;
  rdfs:label "expansion of Actinomycetota in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Actinomycetota up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_2212467 a rdfs:Class ;
  rdfs:label "Bacteroidaceae bacterium" ;
  rdfs:subClassOf obo:NCBITaxon_815 .

obo:NCBITaxon_543 a rdfs:Class ;
  rdfs:label "Enterobacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_91347 .

obo:OHMI_0000373 a rdfs:Class ;
  rdfs:label "expansion of Mogibacterium in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Mogibacterium is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:OHMI_0000256 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidaceae in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Bacteroidaceae in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000255 .

obo:NCBITaxon_74201 a rdfs:Class ;
  rdfs:label "Verrucomicrobiota" ;
  rdfs:subClassOf obo:NCBITaxon_1783257 .

obo:OHMI_0000039 a rdfs:Class ;
  rdfs:label "depletion of Bifidobacterium bifidum in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Bifidobacterium bifidum in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000722 a rdfs:Class ;
  rdfs:label "expansion of Fusobacterium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Fusobacterium up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000772 a rdfs:Class ;
  rdfs:label "expansion of Tannerellaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Tannerellaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_475 a rdfs:Class ;
  rdfs:label "Moraxella" ;
  rdfs:subClassOf obo:NCBITaxon_468 .

obo:NCBITaxon_45658 a rdfs:Class ;
  rdfs:label "Vibrio scophthalmi" ;
  rdfs:subClassOf obo:NCBITaxon_662 .

obo:OHMI_0000895 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000701 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium adolescentis ATCC 15703 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium adolescentis ATCC 15703 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000847 a rdfs:Class ;
  rdfs:label "expansion of Parasutterella in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Parasutterella up-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_584 a rdfs:Class ;
  rdfs:label "Proteus mirabilis" ;
  rdfs:subClassOf obo:NCBITaxon_1903414 .

obo:NCBITaxon_2023 a rdfs:Class ;
  rdfs:label "Thermoactinomyces" ;
  rdfs:subClassOf obo:NCBITaxon_186824 .

obo:OHMI_0000609 a rdfs:Class ;
  rdfs:label "depletion of Veillonella in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Veillonella down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000121 a rdfs:Class ;
  rdfs:label "human skin microbiome interaction"@en ;
  rdfs:comment "An interaction between human and zone of skin microbiome." ;
  rdfs:subClassOf obo:OHMI_0000019 .

obo:NCBITaxon_1021 a rdfs:Class ;
  rdfs:label "Beggiatoa" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:NCBITaxon_638847 a rdfs:Class ;
  rdfs:label "Pyramidobacter" ;
  rdfs:subClassOf obo:NCBITaxon_649776 .

obo:OHMI_0000862 a rdfs:Class ;
  rdfs:label "depletion of Klebsiella in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Klebsiella down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:OHMI_0000920 a rdfs:Class ;
  rdfs:label "expansion of Intestinimonas in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:comment "Intestinimonas up-regulated in gut of adolescent MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000677 .

obo:DOID_848 a rdfs:Class ;
  rdfs:label "arthritis" ;
  rdfs:comment "A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located_in joint and/or redness located_in skin over the joint." ;
  rdfs:subClassOf obo:DOID_1575 , obo:DOID_3342 .

obo:NCBITaxon_32067 a rdfs:Class ;
  rdfs:label "Leptotrichia" ;
  rdfs:subClassOf obo:NCBITaxon_1129771 .

obo:OHMI_0000384 a rdfs:Class ;
  rdfs:label "'depletion of L. reuteri in colorectal cancer human gut'"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Lactobacillus reuteri is decreased." ;
  rdfs:subClassOf obo:OHMI_0000379 .

obo:OHMI_0000646 a rdfs:Class ;
  rdfs:label "expansion of Prevotellaceae in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Prevotellaceae up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:OHMI_0000028 a rdfs:Class ;
  rdfs:label "Clostridioides difficile infection" ;
  rdfs:comment "An infection process that is caused by Clostridioides difficile."@en ;
  rdfs:subClassOf obo:OBI_1110021 .

obo:OHMI_0000872 a rdfs:Class ;
  rdfs:label "depletion of Lactococcus in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Lactococcus down-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:OHMI_0000493 a rdfs:Class ;
  rdfs:label "bacterial change in lung of severe COPD patient compared to mild-moderate COPD"@en ;
  rdfs:comment "COPD human respiratory airway  microbiome interaction that shows an change of bacteria in patients with severe COPD compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000489 .

obo:OBI_0001508 a rdfs:Class ;
  rdfs:label "sampling time measurement datum"@en ;
  rdfs:comment "A time measurement datum when an observation is made or a sample is taken from a material as measured from some reference point." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OHMI_0000002 a rdfs:Class ;
  rdfs:label "human microbiome"@en ;
  rdfs:comment "A microbiome located in a human body" ;
  rdfs:subClassOf obo:OHMI_0000003 .

obo:NCBITaxon_310298 a rdfs:Class ;
  rdfs:label "Phocaeicola coprocola" ;
  rdfs:subClassOf obo:NCBITaxon_909656 .

obo:OHMI_0000556 a rdfs:Class ;
  rdfs:label "expansion of Campylobacteriales in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Campylobacteriales up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000619 a rdfs:Class ;
  rdfs:label "expansion of Aeromonas in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Aeromonas up-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:BFO_0000031 a rdfs:Class ;
  rdfs:label "generically dependent continuant"@en ;
  rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:OHMI_0000132 a rdfs:Class ;
  rdfs:label "expansion of Barnesiella in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an expansion of Barnesiella in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000117 .

obo:OBI_0000067 a rdfs:Class ;
  rdfs:label "evaluant role"@en ;
  rdfs:comment "a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:RO_0000052 a rdf:Property ;
  rdfs:label "characteristic of"@en ;
  rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002314 .

obo:IAO_8000020 a rdfs:Class ;
  rdfs:label "EL++ ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000019 .

obo:OHMI_0000635 a rdfs:Class ;
  rdfs:label "GOLD Stage 2"@en ;
  rdfs:comment "GOLD Stage 2 (or Grade 2) represents Moderate COPD, defined by a post-bronchodilator (Forced Expiratory Volume in 1 second) between 50% and 79% of the predicted value, indicating a moderate limitation in airflow. Patients often experience worsening shortness of breath, increased coughing, and mucus production, making it a common point for seeking medical advice." ;
  rdfs:subClassOf obo:OHMI_0000490 .

obo:NCBITaxon_471189 a rdfs:Class ;
  rdfs:label "Gordonibacter pamelaeae" ;
  rdfs:subClassOf obo:NCBITaxon_644652 .

obo:OHMI_0000184 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium in arthritis  rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Bifidobacterium in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:NCBITaxon_700500 a rdfs:Class ;
  rdfs:label "Catenisphaera adipataccumulans" ;
  rdfs:subClassOf obo:NCBITaxon_128827 .

obo:NCBITaxon_1853550 a rdfs:Class ;
  rdfs:label "[Candida] sp." ;
  rdfs:subClassOf obo:NCBITaxon_4892 .

obo:NCBITaxon_1257 a rdfs:Class ;
  rdfs:label "Peptostreptococcus" ;
  rdfs:subClassOf obo:NCBITaxon_186804 .

obo:NCBITaxon_1654 a rdfs:Class ;
  rdfs:label "Actinomyces" ;
  rdfs:subClassOf obo:NCBITaxon_2049 .

obo:OHMI_0000728 a rdfs:Class ;
  rdfs:label "expansion of Slackia in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Slackia up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_1898203 a rdfs:Class ;
  rdfs:label "Lachnospiraceae bacterium" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000463 a rdfs:Class ;
  rdfs:label "microbiota"@en ;
  rdfs:comment "A collection of microbial organisms that reside in a particular environment." ;
  rdfs:subClassOf obo:PCO_0000000 .

obo:RO_0002351 a rdf:Property ;
  rdfs:label "has member"@en ;
  rdfs:comment "has member is a mereological relation between a collection and an item." ;
  rdfs:range obo:OHMI_0000460 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OHMI_0000769 a rdfs:Class ;
  rdfs:label "expansion of Porphyromonadaceae in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Porphyromonadaceae up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OBI_0000659 a rdfs:Class ;
  rdfs:label "specimen collection process" ;
  rdfs:comment "A planned process with the objective of collecting a specimen." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OHMI_0000599 a rdfs:Class ;
  rdfs:label "depletion of Spirochaetota in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Spirochaetota down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000630 a rdfs:Class ;
  rdfs:label "depletion of Moraxella in lung of severe COPD patient compared to mild-moderate COPD" ;
  rdfs:comment "Moraxella down-regulated in the lung of severe COPD patient compared to mild-moderate COPD." ;
  rdfs:subClassOf obo:OHMI_0000493 .

obo:OHMI_0000444 a rdfs:Class ;
  rdfs:label "expansion of Anoxybacillus in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Anoxybacillus is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000723 a rdfs:Class ;
  rdfs:label "expansion of Gammaproteobacteria in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Gammaproteobacteria up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_356 a rdfs:Class ;
  rdfs:label "Hyphomicrobiales" ;
  rdfs:subClassOf obo:NCBITaxon_28211 .

obo:OHMI_0000390 a rdfs:Class ;
  rdfs:label "depletion of B. animalis in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Bifidobacterium animalis is decreased." ;
  rdfs:subClassOf obo:OHMI_0000393 .

obo:OHMI_0000660 a rdfs:Class ;
  rdfs:label "depletion of Lactobacillus in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Lactobacillus down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:OHMI_0000594 a rdfs:Class ;
  rdfs:label "depletion of Bacilli in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Bacilli down-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:NCBITaxon_3379134 a rdfs:Class ;
  rdfs:label "Pseudomonadati" ;
  rdfs:subClassOf obo:NCBITaxon_2 .

obo:NCBITaxon_194 a rdfs:Class ;
  rdfs:label "Campylobacter" ;
  rdfs:subClassOf obo:NCBITaxon_72294 .

obo:UBERON_0002108 a rdfs:Class ;
  rdfs:label "small intestine" ;
  rdfs:comment "Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]." ;
  rdfs:subClassOf obo:UBERON_0004921 , obo:UBERON_0013765 .

obo:OHMI_0000050 a rdfs:Class ;
  rdfs:label "expansion of Ruminococcus lactaris in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Ruminococcus lactaris in patients with  chronic RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000070 .

obo:OHMI_0000898 a rdfs:Class ;
  rdfs:label "expansion of Asaccharobacter in gut of female MDD patient compared to healthy human" ;
  rdfs:comment "Asaccharobacter up-regulated in gut of female MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000676 .

obo:OHMI_0000797 a rdfs:Class ;
  rdfs:label "depletion of Clostridium sp. CAG:62 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Clostridium sp. CAG:62 down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_35833 a rdfs:Class ;
  rdfs:label "Bilophila wadsworthia" ;
  rdfs:subClassOf obo:NCBITaxon_35832 .

obo:NCBITaxon_630 a rdfs:Class ;
  rdfs:label "Yersinia enterocolitica" ;
  rdfs:subClassOf obo:NCBITaxon_1903411 .

obo:OHMI_0000017 a rdfs:Class ;
  rdfs:label "microbiome in human cutaneous system"@en ;
  rdfs:comment "a human microbiome that is located in a human cutaneous system" ;
  rdfs:subClassOf obo:OHMI_0000002 .

obo:IAO_0000005 a rdfs:Class ;
  rdfs:label "objective specification"@en ;
  rdfs:comment "a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OHMI_0000855 a rdfs:Class ;
  rdfs:label "expansion of Fusobacteriaceae in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:comment "Fusobacteriaceae up-regulated in gut of active-phase MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000675 .

obo:NCBITaxon_2005519 a rdfs:Class ;
  rdfs:label "Barnesiellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_171549 .

obo:OHMI_0000154 a rdfs:Class ;
  rdfs:label "depletion of Ruminococcus in PsA human gut"@en ;
  rdfs:comment "a PsA human-gut microbiome interaction that shows an decrease of Ruminococcus in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000152 .

obo:NCBITaxon_818 a rdfs:Class ;
  rdfs:label "Bacteroides thetaiotaomicron" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:NCBITaxon_91347 a rdfs:Class ;
  rdfs:label "Enterobacterales" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:OBI_0000811 a rdfs:Class ;
  rdfs:label "primary structure of DNA macromolecule" ;
  rdfs:comment "a quality of a DNA molecule that inheres in its bearer due to the order of its DNA nucleotide residues." ;
  rdfs:subClassOf obo:SO_0000001 .

obo:OHMI_0000502 a rdfs:Class ;
  rdfs:label "expansion of Haemophilus influenzae in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Haemophilus influenzae up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:IAO_8000008 a rdfs:Class ;
  rdfs:label "analysis subset ontology module"@en ;
  rdfs:comment "An ontology module that is intended for usage in analysis or discovery applications."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:NCBITaxon_1681 a rdfs:Class ;
  rdfs:label "Bifidobacterium bifidum" ;
  rdfs:subClassOf obo:NCBITaxon_1678 .

obo:OHMI_0000447 a rdfs:Class ;
  rdfs:label "expansion of C. scindens in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where [Clostridium] scindens is increased." ;
  rdfs:subClassOf obo:OHMI_0000406 .

obo:NCBITaxon_85007 a rdfs:Class ;
  rdfs:label "Mycobacteriales" ;
  rdfs:subClassOf obo:NCBITaxon_1760 .

obo:CHEBI_26666 a rdfs:Class ;
  rdfs:label "short-chain fatty acid"@en ;
  rdfs:comment "An aliphatic monocarboxylic acid with a chain length of less than C<small><sub>6</sub></small>. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OHMI_0000582 a rdfs:Class ;
  rdfs:label "expansion of Acinetobacter in lung of exacerbation COPD patient compared to stable COPD" ;
  rdfs:comment "Acinetobacter up-regulated in the lung of exacerbation COPD patient compared to stable COPD." ;
  rdfs:subClassOf obo:OHMI_0000499 .

obo:OHMI_0000541 a rdfs:Class ;
  rdfs:label "expansion of Parvimonas in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Parvimonas up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:NCBITaxon_1262779 a rdfs:Class ;
  rdfs:label "Clostridium sp. CAG:217" ;
  rdfs:subClassOf obo:NCBITaxon_2614128 .

obo:NCBITaxon_84107 a rdfs:Class ;
  rdfs:label "Coriobacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_84999 .

obo:OHMI_0000404 a rdfs:Class ;
  rdfs:label "expansion of Chlamydia in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Chlamydia is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:NCBITaxon_31953 a rdfs:Class ;
  rdfs:label "Bifidobacteriaceae" ;
  rdfs:subClassOf obo:NCBITaxon_85004 .

obo:OHMI_0000530 a rdfs:Class ;
  rdfs:label "expansion of Veillonella in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Veillonella up-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:DOID_5672 a rdfs:Class ;
  rdfs:label "large intestine cancer" ;
  rdfs:comment "An intestinal cancer that effects the long, tube-like organ that is connected to the small intestine at one end and the anus at the other." ;
  rdfs:subClassOf obo:DOID_10155 .

obo:OHMI_0000128 a rdfs:Class ;
  rdfs:label "depletion of Ruminococcaceae in gout human gut"@en ;
  rdfs:comment "a Gout human-gut microbiome interaction that shows an decrease of Ruminococcaceae in patients with gout compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000114 .

obo:NCBITaxon_200940 a rdfs:Class ;
  rdfs:label "Thermodesulfobacteriota" ;
  rdfs:subClassOf obo:NCBITaxon_3379134 .

obo:NCBITaxon_186826 a rdfs:Class ;
  rdfs:label "Lactobacillales" ;
  rdfs:subClassOf obo:NCBITaxon_91061 .

obo:OHMI_0000712 a rdfs:Class ;
  rdfs:label "expansion of Bifidobacterium dentium in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Bifidobacterium dentium up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_33042 a rdfs:Class ;
  rdfs:label "Coprococcus" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000700 a rdfs:Class ;
  rdfs:label "expansion of Akkermansia muciniphila ATCC BAA-835 in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Akkermansia muciniphila ATCC BAA-835 up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OGG_0000000001 a rdfs:Class ;
  rdfs:label "genome"@en ;
  rdfs:comment "A genome is a material entity that represents the entirety of an organism's hereditary information. The genome includes both the genes and the non-coding sequences of the DNA and RNA." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OHMI_0000758 a rdfs:Class ;
  rdfs:label "expansion of Fenollaria in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Fenollaria up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000061 a rdfs:Class ;
  rdfs:label "expansion of Porphyromonas gingivalis in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Porphyromonas gingivalis in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000211 a rdfs:Class ;
  rdfs:label "expansion of Bacteroidales in SLE human gut"@en ;
  rdfs:comment "a SLE human-gut microbiome interaction that shows an expansion of Bacteroidales in patients with SLE compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000210 .

obo:OHMI_0000743 a rdfs:Class ;
  rdfs:label "expansion of Streptococcus in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Streptococcus up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:NCBITaxon_2316020 a rdfs:Class ;
  rdfs:label "Mediterraneibacter" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:OHMI_0000663 a rdfs:Class ;
  rdfs:label "GOLD Stage 4"@en ;
  rdfs:comment "GOLD Stage 4 represents very severe, end-stage COPD, characterized by lung function (FEV1) less than 30% of predicted capacity. It involves chronic, debilitating breathing difficulties, frequent flare-ups, and often requires long-term oxygen therapy. Management focuses on improving quality of life, using medications, pulmonary rehab, and potentially lung-volume reduction surgery." ;
  rdfs:subClassOf obo:OHMI_0000490 .

obo:OHMI_0000288 a rdfs:Class ;
  rdfs:label "expansion of Peptostreptococcusi in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Peptostreptococcus is increased." ;
  rdfs:subClassOf obo:OHMI_0000369 .

obo:OHMI_0000717 a rdfs:Class ;
  rdfs:label "expansion of Eisenbergiella massiliensis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Eisenbergiella massiliensis up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000783 a rdfs:Class ;
  rdfs:label "depletion of Eubacterium ventriosum in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Eubacterium ventriosum down-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000222 a rdfs:Class ;
  rdfs:label "expansion of Eggerthella in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an expansion of Eggerthella in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000085 .

obo:OHMI_0000170 a rdfs:Class ;
  rdfs:label "depletion of Malassezia pachydermatis in PsA human skin"@en ;
  rdfs:comment "a PsA human skin microbiome interaction that shows an decrease of Malassezia pachydermatis in patients with  PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000122 .

obo:NCBITaxon_203682 a rdfs:Class ;
  rdfs:label "Planctomycetota" ;
  rdfs:subClassOf obo:NCBITaxon_1783257 .

obo:OHMI_0000732 a rdfs:Class ;
  rdfs:label "expansion of Parabacteroides in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Parabacteroides up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000411 a rdfs:Class ;
  rdfs:label "expansion of Helicobacter in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Helicobacter is increased." ;
  rdfs:subClassOf obo:OHMI_0000054 .

obo:OHMI_0000641 a rdfs:Class ;
  rdfs:label "expansion of Pseudomonas in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Pseudomonas up-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:NCBITaxon_416916 a rdfs:Class ;
  rdfs:label "Aggregatibacter" ;
  rdfs:subClassOf obo:NCBITaxon_712 .

obo:NCBITaxon_1643826 a rdfs:Class ;
  rdfs:label "Eggerthellaceae" ;
  rdfs:subClassOf obo:NCBITaxon_84998 .

obo:UBERON_0000062 a rdfs:Class ;
  rdfs:label "organ" ;
  rdfs:comment "Anatomical structure that performs a specific function or group of functions [WP]." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:OBI_0000086 a rdfs:Class ;
  rdfs:label "reagent role"@en ;
  rdfs:comment "A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:DOID_686 a rdfs:Class ;
  rdfs:label "liver carcinoma" ;
  rdfs:comment "A liver cancer that has_material_basis_in epithelial cells." ;
  rdfs:subClassOf obo:DOID_305 , obo:DOID_3571 .

obo:OHMI_0000422 a rdfs:Class ;
  rdfs:label "expansion of Prevotella in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Prevotella is increased." ;
  rdfs:subClassOf obo:OHMI_0000375 .

obo:OHMI_0000436 a rdfs:Class ;
  rdfs:label "expansion of Campylobacter jejuni in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Campylobacter jejuni is increased." ;
  rdfs:subClassOf obo:OHMI_0000400 .

obo:NCBITaxon_40674 a rdfs:Class ;
  rdfs:label "Mammalia" ;
  rdfs:subClassOf obo:NCBITaxon_32524 .

obo:NCBITaxon_515619 a rdfs:Class ;
  rdfs:label "Agathobacter rectalis ATCC 33656" ;
  rdfs:subClassOf obo:NCBITaxon_39491 .

obo:OHMI_0000277 a rdfs:Class ;
  rdfs:label "expansion of Diutina rugosa in PsA human gut"@en ;
  rdfs:comment "a PsA human-gut microbiome interaction that shows an expansion of Diutina rugosa in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000152 .

obo:NCBITaxon_10239 a rdfs:Class ;
  rdfs:label "Viruses" ;
  rdfs:subClassOf obo:OHMI_0000460 .

obo:NCBITaxon_1843491 a rdfs:Class ;
  rdfs:label "Selenomonadaceae" ;
  rdfs:subClassOf obo:NCBITaxon_909932 .

obo:OHMI_0000652 a rdfs:Class ;
  rdfs:label "depletion of Prevotella in gut of COPD patient compared to healthy human" ;
  rdfs:comment "Prevotella down-regulated in the gut of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000496 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data entity"@en ;
  rdfs:comment "a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:NCBITaxon_290053 a rdfs:Class ;
  rdfs:label "Bacteroides helcogenes" ;
  rdfs:subClassOf obo:NCBITaxon_816 .

obo:NCBITaxon_613 a rdfs:Class ;
  rdfs:label "Serratia <enterobacteria>" ;
  rdfs:subClassOf obo:NCBITaxon_1903411 .

obo:OHMI_0000340 a rdfs:Class ;
  rdfs:label "expansion of Parabacteroides in colorectal cancer human gut"@en ;
  rdfs:comment "A colorectal cancer human-gut microbiome interaction where Parabacteroides is increased." ;
  rdfs:subClassOf obo:OHMI_0000305 .

obo:OHMI_0000181 a rdfs:Class ;
  rdfs:label "Akkermansia muciniphila depletion in AS rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with ankylosing spondylitis(AS) that shows a depleted quantity of Akkermansia muciniphila in rattus with AS compared with healty controls." ;
  rdfs:subClassOf obo:OHMI_0000110 .

obo:OHMI_0000165 a rdfs:Class ;
  rdfs:label "expansion of Candida albicans in PsA human gut"@en ;
  rdfs:comment "a PsA human-gut microbiome interaction that shows an expansion of Candida albicans in patients with PsA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000152 .

obo:NCBITaxon_2 a rdfs:Class ;
  rdfs:label "Bacteria" ;
  rdfs:subClassOf obo:OHMI_0000460 .

obo:NCBITaxon_651822 a rdfs:Class ;
  rdfs:label "Fretibacterium fastidiosum"@en ;
  rdfs:subClassOf obo:NCBITaxon_1434006 .

obo:OHMI_0000202 a rdfs:Class ;
  rdfs:label "expansion of Streptococcus pyogenes in arthritis  rat gut"@en ;
  rdfs:comment "An association of rattus gut microbiota with arthritis that shows an expansion of Streptococcus pyogenes in rattus with arthritis  compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000183 .

obo:OHMI_0000682 a rdfs:Class ;
  rdfs:label "expansion of Nitrobacter hamburgensis in gut of MDD patient compared to healthy human" ;
  rdfs:comment "Nitrobacter hamburgensis up-regulated in gut of MDD patient compared to healthy human" ;
  rdfs:subClassOf obo:OHMI_0000673 .

obo:OHMI_0000009 a rdfs:Class ;
  rdfs:label "fungal microbiome of mucosal site"@en ;
  rdfs:comment "A fungal microbiome that is located in a mucosal site of a host organism (e.g., urogenital tract, oral cavity, and gastrointestinal tract)" ;
  rdfs:subClassOf obo:OHMI_0000006 .

obo:NCBITaxon_32008 a rdfs:Class ;
  rdfs:label "Burkholderia" ;
  rdfs:subClassOf obo:NCBITaxon_119060 .

obo:NCBITaxon_39497 a rdfs:Class ;
  rdfs:label "Eubacterium xylanophilum" ;
  rdfs:subClassOf obo:NCBITaxon_1730 .

obo:NCBITaxon_653683 a rdfs:Class ;
  rdfs:label "Anaerosporobacter" ;
  rdfs:subClassOf obo:NCBITaxon_186803 .

obo:NCBITaxon_37762 a rdfs:Class ;
  rdfs:label "Escherichia coli B" ;
  rdfs:subClassOf obo:NCBITaxon_562 .

obo:OHMI_0000074 a rdfs:Class ;
  rdfs:label "depletion of Bacteroides in RA human gut"@en ;
  rdfs:comment "a RA human-gut microbiome interaction that shows an decrease of Bacteroides in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:OHMI_0000452 a rdfs:Class ;
  rdfs:label "depletion of Haemophilus spp. in RA human gut"@en ;
  rdfs:comment "a RA human gut microbiome interaction that shows an decrease of Haemophilus sp  in patients with RA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000029 .

obo:NCBITaxon_32524 a rdfs:Class ;
  rdfs:label "Amniota" ;
  rdfs:subClassOf obo:NCBITaxon_32523 .

obo:OHMI_0000571 a rdfs:Class ;
  rdfs:label "depletion of Arthrobacter in lung of COPD patient compared to healthy human" ;
  rdfs:comment "Arthrobacter down-regulated in the lung of COPD patient compared to healthy human." ;
  rdfs:subClassOf obo:OHMI_0000492 .

obo:OHMI_0000476 a rdfs:Class ;
  rdfs:label "host microbiome restoration by DMARD"@en ;
  rdfs:comment "host microbiome restoration by a DMARD treatment" ;
  rdfs:subClassOf obo:OHMI_0000475 .

obo:NCBITaxon_76775 a rdfs:Class ;
  rdfs:label "Malassezia restricta" ;
  rdfs:subClassOf obo:NCBITaxon_55193 .

obo:OHMI_0000671 a rdfs:Class ;
  rdfs:label "SCFA-producing bacteria"@en ;
  rdfs:subClassOf obo:NCBITaxon_2 .

obo:NCBITaxon_407975 a rdfs:Class ;
  rdfs:label "Prevotella pleuritidis"@en ;
  rdfs:subClassOf obo:NCBITaxon_838 .

obo:OHMI_0000267 a rdfs:Class ;
  rdfs:label "expansion of Salmonella in ERA human gut"@en ;
  rdfs:comment "an ERA human-gut microbiome interaction that shows an expansion of Salmonella in patients with ERA compared with healthy controls." ;
  rdfs:subClassOf obo:OHMI_0000257 .

obo:OHMI_0000866 a rdfs:Class ;
  rdfs:label "depletion of Dialister in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:comment "Dialister down-regulated in gut of active-phase MDD patient compared to remission-phase MDD patient" ;
  rdfs:subClassOf obo:OHMI_0000674 .

obo:NCBITaxon_641 a rdfs:Class ;
  rdfs:label "Vibrionaceae" ;
  rdfs:subClassOf obo:NCBITaxon_1236 .

obo:NCBITaxon_213118 a rdfs:Class ;
  rdfs:label "Desulfobacterales" ;
  rdfs:subClassOf obo:NCBITaxon_200940 .

obo:BFO_0000060 a rdf:Property ;
  rdfs:label "obsolete preceded by"@en ;
  rdfs:comment """accidentally included in BFO 1.2 proposal
        - should have been BFO_0000062"""@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000067 a rdf:Property ;
  rdfs:label "contains process"@en ;
  rdfs:comment "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000179 a rdf:Property ;
  rdfs:label "BFO OWL specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ;
  rdfs:range xsd:string .

obo:BFO_0000180 a rdf:Property ;
  rdfs:label "BFO CLIF specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ;
  rdfs:range xsd:string .

obo:IAO_0000111 a rdf:Property ;
  rdfs:label "editor preferred term" ;
  rdfs:comment "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000112 a rdf:Property ;
  rdfs:label "example of usage"@en ;
  rdfs:comment "A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold."@en ;
  rdfs:range xsd:string .

obo:IAO_0000113 a rdf:Property ;
  rdfs:label "in branch"@en ;
  rdfs:comment "An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet."@en ;
  rdfs:range xsd:string .

obo:IAO_0000114 a rdf:Property ;
  rdfs:label "has curation status"@en ;
  rdfs:range xsd:string .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "definition" ;
  rdfs:comment "The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "editor note" ;
  rdfs:comment "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ;
  rdfs:range xsd:string .

obo:IAO_0000117 a rdf:Property ;
  rdfs:label "term editor" ;
  rdfs:comment "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ;
  rdfs:range xsd:string .

obo:IAO_0000118 a rdf:Property ;
  rdfs:label "alternative label"@en ;
  rdfs:comment "A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like."@en ;
  rdfs:range xsd:string .

obo:IAO_0000119 a rdf:Property ;
  rdfs:label "definition source"@en ;
  rdfs:comment "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ;
  rdfs:range xsd:string .

obo:IAO_0000231 a rdf:Property ;
  rdfs:label "has obsolescence reason"@en ;
  rdfs:comment "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ;
  rdfs:range xsd:string .

obo:IAO_0000232 a rdf:Property ;
  rdfs:label "curator note"@en ;
  rdfs:comment "An administrative note of use for a curator but of no use for a user"@en ;
  rdfs:range xsd:string .

obo:IAO_0000233 a rdf:Property ;
  rdfs:label "term tracker item"@en ;
  rdfs:comment "An IRI or similar locator for a request or discussion of an ontology term." ;
  rdfs:range xsd:anyURI .

obo:IAO_0000234 a rdf:Property ;
  rdfs:label "ontology term requester"@en ;
  rdfs:comment "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition."@en ;
  rdfs:range xsd:string .

obo:IAO_0000411 a rdf:Property ;
  rdfs:label "is denotator type"@en ;
  rdfs:comment "Relates an class defined in an ontology, to the type of it's denotator"@en ;
  rdfs:range xsd:string .

obo:IAO_0000412 a rdf:Property ;
  rdfs:label "imported from"@en ;
  rdfs:comment "For external terms/classes, the ontology from which the term was imported"@en ;
  rdfs:range xsd:string .

obo:IAO_0000424 a rdf:Property ;
  rdfs:label "expand expression to"@en ;
  rdfs:comment "A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en ;
  rdfs:range xsd:string .

obo:IAO_0000425 a rdf:Property ;
  rdfs:label "expand assertion to"@en ;
  rdfs:comment "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en ;
  rdfs:range xsd:string .

obo:IAO_0000426 a rdf:Property ;
  rdfs:label "first order logic expression"@en ;
  rdfs:range xsd:string .

obo:IAO_0000427 a rdf:Property ;
  rdfs:label "antisymmetric property"@en ;
  rdfs:comment "Use boolean value xsd:true to indicate that the property is an antisymmetric property"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OMO_0001001 .

obo:IAO_0000589 a rdf:Property ;
  rdfs:label "OBO foundry unique label"@en ;
  rdfs:comment "An alternative name for a class or property which is unique across the OBO Foundry."@en ;
  rdfs:range xsd:string .

obo:IAO_0000596 a rdf:Property ;
  rdfs:label "has ID digit count"@en ;
  rdfs:comment "Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix\" annotation property value concatenated with an integer in the id range (left padded with \"0\"s to make this many digits)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000597 a rdf:Property ;
  rdfs:label "has ID range allocated to"@en ;
  rdfs:comment "Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms"@en ;
  rdfs:range xsd:string .

obo:IAO_0000598 a rdf:Property ;
  rdfs:label "has ID policy for"@en ;
  rdfs:comment "Relating an ontology used to record id policy to the ontology namespace whose policy it manages"@en ;
  rdfs:range xsd:string .

obo:IAO_0000599 a rdf:Property ;
  rdfs:label "has ID prefix"@en ;
  rdfs:comment "Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with \"0\"s to make this many digits) to construct an ID for a term being created."@en ;
  rdfs:range xsd:string .

obo:IAO_0000600 a rdf:Property ;
  rdfs:label "elucidation"@en ;
  rdfs:range xsd:string .

obo:IAO_0000601 a rdf:Property ;
  rdfs:label "has associated axiom(nl)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000602 a rdf:Property ;
  rdfs:label "has associated axiom(fol)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000603 a rdf:Property ;
  rdfs:label "is allocated id range"@en ;
  rdfs:comment "Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. \"IAO_0020000-IAO_0020999\""@en ;
  rdfs:range xsd:string .

obo:IAO_0000700 a rdf:Property ;
  rdfs:label "has ontology root term"@en ;
  rdfs:comment "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ;
  rdfs:range xsd:string .

obo:IAO_0006011 a rdf:Property ;
  rdfs:label "may be identical to"@en ;
  rdfs:comment "A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged."@en ;
  rdfs:range xsd:string .

obo:IAO_0006012 a rdf:Property ;
  rdfs:label "scheduled for obsoletion on or after"@en ;
  rdfs:comment "Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date."@en ;
  rdfs:range xsd:dateTime .

obo:IAO_0010000 a rdf:Property ;
  rdfs:label "has axiom label"@en ;
  rdfs:range xsd:string .

obo:IAO_0100001 a rdf:Property ;
  rdfs:label "term replaced by"@en ;
  rdfs:comment "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
  rdfs:range xsd:string .

obo:INO_0000006 a rdf:Property ;
  rdfs:label "has literature mining keywords"@en ;
  rdfs:comment "an annotation property that lists keyword(s) useful for literature tagging and retrieval of sentences containing the type (or kind) of entity (e.g., interaction) as shown by the ontology term label and definition. " ;
  rdfs:range xsd:string .

obo:OBI_0000295 a rdf:Property ;
  rdfs:label "is_specified_input_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:range obo:OBI_0000011 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:OBI_0001847 a rdf:Property ;
  rdfs:label "ISA alternative term"@en ;
  rdfs:comment "An alternative term used by the ISA tools project (http://isa-tools.org)." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:OBI_0001886 a rdf:Property ;
  rdfs:label "NIAID GSCID-BRC alternative term"@en ;
  rdfs:comment "An alternative term used by the National Institute of Allergy and Infectious Diseases (NIAID) Genomic Sequencing Centers for Infectious Diseases (GSCID) and Bioinformatics Resource Centers (BRC)." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:OBI_9991118 a rdf:Property ;
  rdfs:label "IEDB alternative term" ;
  rdfs:comment "An alternative term used by the IEDB." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:OHMI_0000031 a rdf:Property ;
  rdfs:label "evidence publication"@en ;
  rdfs:comment "An annotation property that represents a publication that includes the evidence of the presence of a class type." ;
  rdfs:range xsd:string .

obo:OHMI_0000055 a rdf:Property ;
  rdfs:label "microbe susceptibly expanded in host with disease"@en ;
  rdfs:comment "An object property that represents the susceptible increase (compared to healthy control) of the population of a microbe in a host with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000313 .

obo:OHMI_0000056 a rdf:Property ;
  rdfs:label "microbe susceptibly expanded in human with disease"@en ;
  rdfs:comment "An object property that represents the susceptible increase (compared to healthy control) of the population of a microbe in a human with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000055 .

obo:OHMI_0000060 a rdf:Property ;
  rdfs:label "obsolete has disease" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OHMI_0000209 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted in host with disease"@en ;
  rdfs:comment "An object property that represents the susceptible decrease (compared to healthy control) of the population of a microbe in a host with a specific disease. The susceptibility is usually derived from peer-reviewed studies. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 ;
  rdfs:subPropertyOf obo:OHMI_0000313 .

obo:OHMI_0000214 a rdf:Property ;
  rdfs:label "microbial population phenotype in host"@en ;
  rdfs:comment "this is a shortcut object property that represents the phenotype that exists in a microbial population inside a host." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OHMI_0000232 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted in human with disease"@en ;
  rdfs:comment "An object property that represents the susceptible decrease (compared to healthy control) of the population of a microbe in a human with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000209 .

obo:OHMI_0000252 a rdf:Property ;
  rdfs:label "obsolete has phenotype" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OHMI_0000284 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted in rat with disease"@en ;
  rdfs:comment "An object property that represents the susceptible decrease (compared to healthy control) of the population of a microbe in a rat with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000209 .

obo:OHMI_0000301 a rdf:Property ;
  rdfs:label "microbe susceptibly expanded in rat with disease"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000055 .

obo:OHMI_0000303 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted in gut of rat with disease"@en ;
  rdfs:comment "An object property that represents the susceptible decrease (compared to healthy control) of the population of a microbe in the gut of a rat with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000284 .

obo:OHMI_0000313 a rdf:Property ;
  rdfs:label "microbe susceptibly changed in host with disease"@en ;
  rdfs:comment "An object property that represents the susceptible change (compared to healthy control) of the population of a microbe in a host with a specific disease. This is a shortcut relation where the domain is microbe, and the range is a disease." ;
  rdfs:range obo:DOID_4 .

obo:OHMI_0000358 a rdf:Property ;
  rdfs:label "microbe susceptibly expanded in mouse with disease"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000055 .

obo:OHMI_0000363 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted in mouse with disease"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000209 .

obo:OHMI_0000364 a rdf:Property ;
  rdfs:label "microbe susceptibly depleted in gut of mouse with disease"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000363 .

obo:OHMI_0000481 a rdf:Property ;
  rdfs:label "obsolete has host" ;
  rdfs:comment "an object subproperty of 'has participant' in which the participant is a host organism." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OHMI_0000486 a rdf:Property ;
  rdfs:label "has microbe expanded compared to gastritis"@en ;
  rdfs:comment "an object property that represents the relation between a host-microbiome interaction and a microbe where the population of the microbe is expanded in a diseased host compared to a host with gastritis." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000467 .

obo:OHMI_0000487 a rdf:Property ;
  rdfs:label "has microbe expanded compared to superficial gastritis"@en ;
  rdfs:comment "an object property that represents the relation between a host-microbiome interaction and a microbe where the population of the microbe is expanded in a diseased host compared to a host with superficial gastritis." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OHMI_0000486 .

obo:OMO_0001001 a rdf:Property ;
  rdfs:label "logical characteristic of object property" ;
  rdfs:comment "This is an annotation used on an object property to indicate a logical characterstic beyond what is possible in OWL." ;
  rdfs:range xsd:string .

obo:OMO_0002000 a rdf:Property ;
  rdfs:label "defined by construct" ;
  rdfs:comment "Links an annotation property to a SPARQL CONSTRUCT query which is meant to provide semantics for a shortcut relation." ;
  rdfs:range xsd:string .

obo:OMO_0002001 a rdf:Property ;
  rdfs:label "preferred label for community" ;
  rdfs:comment "A provenance property that denotes a synonym to be the preferred one for a specific community." ;
  rdfs:range xsd:string .

obo:OMO_0003000 a rdf:Property ;
  rdfs:label "abbreviation" ;
  rdfs:comment "A synonym type for describing abbreviations or initialisms" ;
  rdfs:range xsd:string .

obo:OMO_0003001 a rdf:Property ;
  rdfs:label "ambiguous synonym" ;
  rdfs:comment "A synonym type for describing ambiguous synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003002 a rdf:Property ;
  rdfs:label "dubious synonym" ;
  rdfs:comment "A synonym type for describing dubious synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003003 a rdf:Property ;
  rdfs:label "layperson synonym" ;
  rdfs:comment "A synonym type for describing layperson or colloquial synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003004 a rdf:Property ;
  rdfs:label "plural form" ;
  rdfs:comment "A synonym type for describing pluralization synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003005 a rdf:Property ;
  rdfs:label "UK spelling synonym" ;
  rdfs:comment "A synonym type for describing UK spelling variants" ;
  rdfs:range xsd:string .

obo:OMO_0003006 a rdf:Property ;
  rdfs:label "misspelling" ;
  rdfs:comment "A synonym type for common misspellings" ;
  rdfs:range xsd:string .

obo:OMO_0003007 a rdf:Property ;
  rdfs:label "misnomer" ;
  rdfs:comment "A synonym type for misnomers, i.e., a synonym that is not technically correct but is commonly used anyway" ;
  rdfs:range xsd:string .

obo:OMO_0003008 a rdf:Property ;
  rdfs:label "previous name" ;
  rdfs:comment "A synonym type for names that have been used as primary labels in the past." ;
  rdfs:range xsd:string .

obo:OMO_0003009 a rdf:Property ;
  rdfs:label "legal name" ;
  rdfs:comment "A synonym type for the legal entity name" ;
  rdfs:range xsd:string .

obo:OMO_0003010 a rdf:Property ;
  rdfs:label "International Nonproprietary Name" ;
  rdfs:comment "The International Nonproprietary Name (INN) is a standardize name for a pharmaceutical drug or active ingredient issued by the World Health Organization (WHO) meant to address the issues with country- or language-specific brand names. These are issued in several languages, including English, Latin, French, Russian, Spanish, Arabic, and Chinese." ;
  rdfs:range xsd:string .

obo:OMO_0003011 a rdf:Property ;
  rdfs:label "latin term" ;
  rdfs:comment "A synonym type for describing Latin term synonyms." ;
  rdfs:range xsd:string .

obo:OMO_0003012 a rdf:Property ;
  rdfs:label "acronym" ;
  rdfs:comment "A synonym type for describing abbreviations that are a part of the full name's words, such as initialisms or alphabetisms." ;
  rdfs:range xsd:string .

obo:OMO_0003014 a rdf:Property ;
  rdfs:label "has ontology hierarchical property" ;
  rdfs:comment "Relates an ontology to predicates/properties that should be used by user interfaces to render the hierarchical structure of the ontology. Typically, this is rdfs:subClassOf, but in ontologies that are partonomies, this might also include BFO:0000050 (part of). Tools like OLS can use predicates annotated with this property for rendering the ontology class hierarchy. There can be more than one hierarchical property. In the absence of any, it should be assumed that it is rdfs:subClassOf." ;
  rdfs:range xsd:string .

obo:OMO_0004000 a rdf:Property ;
  rdfs:label "has symbol" ;
  rdfs:comment "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity." ;
  rdfs:range xsd:string .

obo:RO_0000053 a rdf:Property ;
  rdfs:label "has characteristic"@en ;
  rdfs:comment "Inverse of characteristic_of"@en ;
  rdfs:range obo:BFO_0000020 .

obo:RO_0000092 a rdf:Property ;
  rdfs:label "disposition of"@en ;
  rdfs:comment "inverse of has disposition" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0001001 a rdf:Property ;
  rdfs:label "derives into"@en ;
  rdfs:comment "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001900 a rdf:Property ;
  rdfs:label "temporal interpretation" ;
  rdfs:comment "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0002017 a rdf:Property ;
  rdfs:label "has component activity" ;
  rdfs:comment "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002018 .

obo:RO_0002025 a rdf:Property ;
  rdfs:label "has effector activity" ;
  rdfs:comment "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002017 .

obo:RO_0002081 a rdf:Property ;
  rdfs:label "before or simultaneous with"@en ;
  rdfs:comment "Primitive instance level timing relation between events" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002082 a rdf:Property ;
  rdfs:label "simultaneous with"@en ;
  rdfs:comment "x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002081 .

obo:RO_0002083 a rdf:Property ;
  rdfs:label "before"@en ;
  rdfs:comment "t1 before t2 iff:=  t1 before_or_simulataneous_with t2  and not (t1 simultaeous_with t2)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002081 .

obo:RO_0002084 a rdf:Property ;
  rdfs:label "during which ends"@en ;
  rdfs:comment "Previously had ID  http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point.  No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line.  Official ID now chosen from DOS ID range." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002085 a rdf:Property ;
  rdfs:label "encompasses"@en ;
  rdfs:comment "Previously had ID  http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point.  No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line.  Official ID now chosen from DOS ID range." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002088 .

obo:RO_0002086 a rdf:Property ;
  rdfs:label "ends after"@en ;
  rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002087 a rdf:Property ;
  rdfs:label "immediately preceded by"@en ;
  rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000062 .

obo:RO_0002088 a rdf:Property ;
  rdfs:label "during which starts"@en ;
  rdfs:comment "Previously had ID  http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point.  No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line.  Official ID now chosen from DOS ID range." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002089 a rdf:Property ;
  rdfs:label "starts before"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002090 a rdf:Property ;
  rdfs:label "immediately precedes"@en ;
  rdfs:comment "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000063 .

obo:RO_0002092 a rdf:Property ;
  rdfs:label "happens during"@en ;
  rdfs:comment "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))"@en ;
  rdfs:seeAlso <https://wiki.geneontology.org/Happens_during> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002093 , obo:RO_0002091 .

obo:RO_0002093 a rdf:Property ;
  rdfs:label "ends during"@en ;
  rdfs:comment "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). "@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002131 a rdf:Property ;
  rdfs:label "overlaps"@en ;
  rdfs:comment "x overlaps y if and only if there exists some z such that x has part z and z part of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0002172 a rdf:Property ;
  rdfs:label "taxonomic class assertion"@en ;
  rdfs:comment "An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002420 .

obo:RO_0002175 a rdf:Property ;
  rdfs:label "present in taxon"@en ;
  rdfs:comment "S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S" ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002172 .

obo:RO_0002180 a rdf:Property ;
  rdfs:label "has component"@en ;
  rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Submissions:Componency> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002201 a rdf:Property ;
  rdfs:label "phenotype of"@en ;
  rdfs:comment "inverse of has phenotype" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002212 a rdf:Property ;
  rdfs:label "negatively regulates"@en ;
  rdfs:comment "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002305 , obo:RO_0002211 .

obo:RO_0002213 a rdf:Property ;
  rdfs:label "positively regulates"@en ;
  rdfs:comment "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002304 , obo:RO_0002211 .

obo:RO_0002223 a rdf:Property ;
  rdfs:label "starts"@en ;
  rdfs:comment "inverse of starts with" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000050 .

obo:RO_0002224 a rdf:Property ;
  rdfs:label "starts with"@en ;
  rdfs:comment "x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000051 .

obo:RO_0002229 a rdf:Property ;
  rdfs:label "ends"@en ;
  rdfs:comment "inverse of ends with" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000050 .

obo:RO_0002230 a rdf:Property ;
  rdfs:label "ends with"@en ;
  rdfs:comment "x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000051 .

obo:RO_0002234 a rdf:Property ;
  rdfs:label "has output"@en ;
  rdfs:comment "p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Has_output> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002304 a rdf:Property ;
  rdfs:label "causally upstream of, positive effect" ;
  rdfs:comment "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Causally_upstream_of,_positive_effect> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004047 , obo:RO_0002411 .

obo:RO_0002305 a rdf:Property ;
  rdfs:label "causally upstream of, negative effect" ;
  rdfs:comment "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Causally_upstream_of,_negative_effect> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004046 , obo:RO_0002411 .

obo:RO_0002314 a rdf:Property ;
  rdfs:label "characteristic of part of"@en ;
  rdfs:comment "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/reflexivity/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002502 .

obo:RO_0002321 a rdf:Property ;
  rdfs:label "ecologically related to"@en ;
  rdfs:comment "A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002323 a rdf:Property ;
  rdfs:label "mereotopologically related to"@en ;
  rdfs:comment "A mereological relationship or a topological relationship" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002328 a rdf:Property ;
  rdfs:label "functionally related to"@en ;
  rdfs:comment "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002335 a rdf:Property ;
  rdfs:label "negatively regulated by"@en ;
  rdfs:comment "inverse of negatively regulates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002336 a rdf:Property ;
  rdfs:label "positively regulated by"@en ;
  rdfs:comment "inverse of positively regulates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002352 a rdf:Property ;
  rdfs:label "input of"@en ;
  rdfs:comment "inverse of has input" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .

obo:RO_0002353 a rdf:Property ;
  rdfs:label "output of"@en ;
  rdfs:comment "inverse of has output" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .

obo:RO_0002404 a rdf:Property ;
  rdfs:label "causally downstream of"@en ;
  rdfs:comment "inverse of upstream of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002427 , obo:BFO_0000062 .

obo:RO_0002405 a rdf:Property ;
  rdfs:label "immediately causally downstream of"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002404 , obo:RO_0002087 .

obo:RO_0002407 a rdf:Property ;
  rdfs:label "indirectly positively regulates"@en ;
  rdfs:comment "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Indirectly_positively_regulates> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002213 .

obo:RO_0002409 a rdf:Property ;
  rdfs:label "indirectly negatively regulates"@en ;
  rdfs:comment "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Indirectly_negatively_regulates> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002212 .

obo:RO_0002410 a rdf:Property ;
  rdfs:label "causally related to"@en ;
  rdfs:comment "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002411 a rdf:Property ;
  rdfs:label "causally upstream of"@en ;
  rdfs:comment "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000063 .

obo:RO_0002412 a rdf:Property ;
  rdfs:label "immediately causally upstream of"@en ;
  rdfs:comment "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 , obo:RO_0002090 .

obo:RO_0002413 a rdf:Property ;
  rdfs:label "provides input for"@en ;
  rdfs:comment "p provides input for q iff p is immediately causally upstream of q, and there exists some c such that p has_output c and q has_input c." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Provides_input_for> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002414 , obo:RO_0002412 .

obo:RO_0002416 a rdf:Property ;
  rdfs:label "logical macro assertion"@en ;
  rdfs:comment "An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/shortcut-relations/> ;
  rdfs:range xsd:string .

obo:RO_0002418 a rdf:Property ;
  rdfs:label "causally upstream of or within" ;
  rdfs:comment "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002420 a rdf:Property ;
  rdfs:label "logical macro assertion on a class"@en ;
  rdfs:comment "A logical macro assertion whose domain is an IRI for a class" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002416 .

obo:RO_0002421 a rdf:Property ;
  rdfs:label "logical macro assertion on a property"@en ;
  rdfs:comment "A logical macro assertion whose domain is an IRI for a property" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002416 .

obo:RO_0002422 a rdf:Property ;
  rdfs:label "logical macro assertion on an object property"@en ;
  rdfs:comment "Used to annotate object properties to describe a logical meta-property or characteristic of the object property." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002421 .

obo:RO_0002423 a rdf:Property ;
  rdfs:label "logical macro assertion on an annotation property"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002421 .

obo:RO_0002427 a rdf:Property ;
  rdfs:label "causally downstream of or within" ;
  rdfs:comment "inverse of causally upstream of or within" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002440 a rdf:Property ;
  rdfs:label "symbiotically interacts with" ;
  rdfs:comment "A biotic interaction in which the two organisms live together in more or less intimate association." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002574 .

obo:RO_0002454 a rdf:Property ;
  rdfs:label "has host" ;
  rdfs:comment "X 'has host' y if and only if: x is an organism, y is an organism, and x can live on the surface of or within the body of y" ;
  rdfs:seeAlso <http://eol.org/schema/terms/hasHost> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002440 .

obo:RO_0002461 a rdf:Property ;
  rdfs:label "partner in" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0002464 a rdf:Property ;
  rdfs:label "helper property (not for use in curation)" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002465 a rdf:Property ;
  rdfs:label "is symbiosis" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002563 .

obo:RO_0002502 a rdf:Property ;
  rdfs:label "depends on" ;
  rdfs:seeAlso obo:BFO_0000169 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002563 a rdf:Property ;
  rdfs:label "interaction relation helper property" ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29> , <http://purl.obolibrary.org/obo/ro/docs/interaction-relations/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002464 .

obo:RO_0002575 a rdf:Property ;
  rdfs:label "is direct form of" ;
  rdfs:comment "relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y" ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/direct-and-indirect-relations/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0002578 a rdf:Property ;
  rdfs:label "directly regulates" ;
  rdfs:comment "p directly regulates q iff p is immediately causally upstream of q and p regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002412 , obo:RO_0002211 .

obo:RO_0002579 a rdf:Property ;
  rdfs:label "is indirect form of" ;
  rdfs:comment "relation p is the indirect form of relation q iff p is a subPropertyOf q, and there exists some p' such that p' is the direct form of q, p' o p' -> p, and forall x,y : x q y -> either (1) x p y or (2) x p' y" ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/direct-and-indirect-relations/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0002629 a rdf:Property ;
  rdfs:label "directly positively regulates" ;
  rdfs:comment "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Directly_positively_regulates> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002213 .

obo:RO_0002630 a rdf:Property ;
  rdfs:label "directly negatively regulates" ;
  rdfs:comment "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Directly_negatively_regulates> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002212 .

obo:RO_0004046 a rdf:Property ;
  rdfs:label "causally upstream of or within, negative effect" ;
  rdfs:seeAlso <https://wiki.geneontology.org/Causally_upstream_of_or_within,_negative_effect> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 .

obo:RO_0004047 a rdf:Property ;
  rdfs:label "causally upstream of or within, positive effect" ;
  rdfs:seeAlso <https://wiki.geneontology.org/Causally_upstream_of_or_within,_positive_effect> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 .

obo:RO_0004048 a rdf:Property ;
  rdfs:label "is directional form of" ;
  rdfs:comment "Used to annotate object properties representing a causal relationship where the value indicates a direction. Should be \"+\", \"-\" or \"0\"" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0004049 a rdf:Property ;
  rdfs:label "is positive form of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004048 .

obo:RO_0004050 a rdf:Property ;
  rdfs:label "is negative form of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004048 .

obo:RO_0012009 a rdf:Property ;
  rdfs:label "constitutively upstream of"@en ;
  rdfs:comment "p is constitutively upstream of q iff p is causally upstream of q, p is required for execution of q or a part of q, and the execution of p is approximately constant." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Constitutively_upstream_of> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002304 .

obo:RO_0012010 a rdf:Property ;
  rdfs:label "removes input for"@en ;
  rdfs:comment "p removes input for q iff p is causally upstream of q, there exists some c such that p has_input c and q has_input c, p reduces the levels of c, and c is rate limiting for execution of q." ;
  rdfs:seeAlso <https://wiki.geneontology.org/Removes_input_for> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002305 .

obo:RO_0012011 a rdf:Property ;
  rdfs:label "indirectly causally upstream of"@en ;
  rdfs:comment "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0012012 a rdf:Property ;
  rdfs:label "indirectly regulates"@en ;
  rdfs:comment "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0012011 , obo:RO_0002211 .

obo:RO_0016001 a rdf:Property ;
  rdfs:label "has phenotype or disease" ;
  rdfs:seeAlso <https://github.com/oborel/obo-relations/issues/478> ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0016002 a rdf:Property ;
  rdfs:label "has disease" ;
  rdfs:comment "A relationship that holds between an organism and a disease. Here a disease is construed broadly as a disposition to undergo pathological processes that exists in an organism because of one or more disorders in that organism." ;
  rdfs:seeAlso <https://github.com/oborel/obo-relations/issues/478> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0016001 .

obo:RO_0040042 a rdf:Property ;
  rdfs:label "is homeomorphic for" ;
  rdfs:comment "R is homemorphic for C iff (1) there exists some x,y such that x R y, and x and y instantiate C and (2) for all x, if x is an instance of C, and there exists some y some such that x R y, then it follows that y is an instance of C." ;
  rdfs:seeAlso <https://github.com/oborel/obo-relations/issues/164> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:UBPROP_0000001 a rdf:Property ;
  rdfs:label "external_definition" ;
  rdfs:comment "An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class." ;
  rdfs:range xsd:string .

obo:UBPROP_0000003 a rdf:Property ;
  rdfs:label "homology_notes" ;
  rdfs:comment "Notes on the homology status of this class." ;
  rdfs:range xsd:string .

obo:UBPROP_0000007 a rdf:Property ;
  rdfs:label "has_relational_adjective" ;
  rdfs:range xsd:string .

obo:UBPROP_0000008 a rdf:Property ;
  rdfs:label "taxon_notes" ;
  rdfs:comment "Notes on the how instances of this class vary across species." ;
  rdfs:range xsd:string .

obo:UBPROP_0000011 a rdf:Property ;
  rdfs:label "development_notes" ;
  rdfs:comment "Notes on the ontogenic development of instances of this class." ;
  rdfs:range xsd:string .

obo:UBPROP_0000012 a rdf:Property ;
  rdfs:label "external_ontology_notes" ;
  rdfs:comment "Notes on how similar or equivalent classes are represented in other ontologies." ;
  rdfs:range xsd:string .

<http://xmlns.com/foaf/0.1/depicted_by> a rdf:Property ;
  rdfs:label "depicted by" ;
  rdfs:range xsd:string .

<http://www.w3.org/2002/07/owl#real> a rdfs:Datatype .

obo:IAO_0000078 a rdfs:Class ;
  rdfs:label "curation status specification"@en ;
  rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000002 a obo:IAO_0000078 ;
  rdfs:label "example to be eventually removed"@en .

obo:IAO_0000120 a obo:IAO_0000078 ;
  rdfs:label "metadata complete"@en ;
  rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en .

obo:IAO_0000121 a obo:IAO_0000078 ;
  rdfs:label "organizational term"@en ;
  rdfs:comment "term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en .

obo:IAO_0000122 a obo:IAO_0000078 ;
  rdfs:label "ready for release"@en ;
  rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en .

obo:IAO_0000123 a obo:IAO_0000078 ;
  rdfs:label "metadata incomplete"@en ;
  rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en .

obo:IAO_0000124 a obo:IAO_0000078 ;
  rdfs:label "uncurated"@en ;
  rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en .

obo:IAO_0000125 a obo:IAO_0000078 ;
  rdfs:label "pending final vetting"@en ;
  rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en .

obo:IAO_0000423 a obo:IAO_0000078 ;
  rdfs:label "to be replaced with external ontology term"@en ;
  rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en .

obo:IAO_0000428 a obo:IAO_0000078 ;
  rdfs:label "requires discussion"@en ;
  rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .

obo:IAO_0000225 a rdfs:Class ;
  rdfs:label "obsolescence reason specification"@en ;
  rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000103 a obo:IAO_0000225 ;
  rdfs:label "failed exploratory term"@en ;
  rdfs:comment "The term was initially used in an attempt to structure part of the ontology, but in retrospect failed to do a good job."@en .

obo:IAO_0000226 a obo:IAO_0000225 ;
  rdfs:label "placeholder removed"@en ;
  rdfs:comment "The term was created to temporarily stand in for a semantic purpose, but is no longer needed, typically due to another permanent term being defined."@en .

obo:IAO_0000227 a obo:IAO_0000225 ;
  rdfs:label "terms merged"@en ;
  rdfs:comment "The term has been combined with one or more other terms to create a more encompassing (merged) term."@en .

obo:IAO_0000228 a obo:IAO_0000225 ;
  rdfs:label "term imported"@en ;
  rdfs:comment "The term has been replaced by a term imported from another ontology."@en .

obo:IAO_0000229 a obo:IAO_0000225 ;
  rdfs:label "term split"@en ;
  rdfs:comment "The term has been split into two or more new terms."@en .

obo:OMO_0001000 a obo:IAO_0000225 ;
  rdfs:label "out of scope" ;
  rdfs:comment "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en .

obo:IAO_0000409 a rdfs:Class ;
  rdfs:label "denotator type"@en ;
  rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000410 a obo:IAO_0000409 ;
  rdfs:label "universal"@en .

obo:IAO_0000420 a obo:IAO_0000409 ;
  rdfs:label "defined class"@en ;
  rdfs:comment "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en .

obo:IAO_0000421 a obo:IAO_0000409 ;
  rdfs:label "named class expression"@en ;
  rdfs:comment "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en .

obo:OBI_0000639 a rdfs:Class ;
  rdfs:label "material separation objective" ;
  rdfs:comment "is an objective to transform a material entity into spatially separated components." ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:OBI_0000678 a obo:OBI_0000639 ;
  rdfs:label "portioning objective" ;
  rdfs:comment "A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material." .

obo:OBI_0000681 a obo:OBI_0000639 ;
  rdfs:label "separation into different composition objective" ;
  rdfs:comment "A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities)." .
